# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Esterase_phd PF10503.9 OEU05644.1 - 0.00055 19.5 1.5 0.0013 18.3 1.5 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OEU05644.1 - 0.00076 19.0 0.4 0.062 12.8 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OEU05644.1 - 0.0012 18.7 0.2 0.002 17.9 0.2 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OEU05644.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 OEU05644.1 - 0.081 11.8 0.1 0.12 11.3 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme CtnDOT_TraJ PF07863.11 OEU05644.1 - 0.085 13.5 0.0 0.29 11.8 0.0 1.9 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Esterase PF00756.20 OEU05644.1 - 0.17 11.5 0.7 0.24 11.0 0.7 1.4 1 1 0 1 1 1 0 Putative esterase BUD22 PF09073.10 OEU05646.1 - 1e-15 58.1 18.9 1.3e-15 57.7 18.9 1.1 1 0 0 1 1 1 1 BUD22 rve PF00665.26 OEU05649.1 - 0.0051 17.0 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Pyrid_oxidase_2 PF13883.6 OEU05652.1 - 1.6e-15 57.5 0.0 2.6e-15 56.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CLASP_N PF12348.8 OEU05653.1 - 1.5e-11 44.3 0.0 3.3e-11 43.2 0.0 1.4 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 OEU05653.1 - 2.6e-08 33.4 0.9 1 9.8 0.0 4.7 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 OEU05653.1 - 0.021 14.9 0.4 8.6 6.4 0.2 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 XPG_N PF00752.17 OEU05654.1 - 5.8e-19 68.5 0.2 1.1e-17 64.4 0.0 2.9 2 1 0 2 2 2 1 XPG N-terminal domain PGA2 PF07543.12 OEU05654.1 - 8.3 6.4 29.4 0.065 13.2 13.9 3.4 3 1 0 3 3 3 0 Protein trafficking PGA2 ShK PF01549.24 OEU05656.1 - 0.0076 16.8 9.2 0.0076 16.8 9.2 6.8 5 4 0 5 5 5 2 ShK domain-like Glyco_hydro81C PF17652.1 OEU05663.1 - 5.7e-69 233.0 4.6 1e-68 232.2 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OEU05663.1 - 4.6e-27 95.0 2.1 1e-13 51.2 0.1 3.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain LPP20 PF02169.16 OEU05663.1 - 0.088 13.2 2.6 1.1 9.6 0.0 3.2 3 0 0 3 3 3 0 LPP20 lipoprotein COX1 PF00115.20 OEU05664.1 - 1.1e-17 64.0 3.9 1.3e-17 63.9 3.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I zf-MYND PF01753.18 OEU05665.1 - 8.5e-06 25.8 17.5 1.4e-05 25.1 17.5 1.4 1 0 0 1 1 1 1 MYND finger PDZ_6 PF17820.1 OEU05666.1 - 6.6e-08 32.3 0.1 1.2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU05666.1 - 1.3e-06 28.6 0.2 4.9e-06 26.8 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OEU05666.1 - 5e-06 26.8 0.3 1.3e-05 25.4 0.3 1.7 1 0 0 1 1 1 1 PDZ domain FlxA PF14282.6 OEU05666.1 - 3.1 7.8 9.5 0.74 9.8 0.1 2.8 3 0 0 3 3 3 0 FlxA-like protein RVT_3 PF13456.6 OEU05667.1 - 0.0004 20.2 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like HDC PF02329.16 OEU05668.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain TENA_THI-4 PF03070.16 OEU05670.1 - 0.00025 20.9 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 TENA/THI-4/PQQC family TPR_2 PF07719.17 OEU05671.1 - 0.013 15.6 2.0 2.5 8.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU05671.1 - 0.014 15.7 4.8 2.5 8.4 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU05671.1 - 0.29 11.4 2.0 1 9.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU05671.1 - 4.8 7.2 5.2 27 4.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ArsP_2 PF11449.8 OEU05672.1 - 0.05 12.8 0.8 0.14 11.4 0.7 1.5 1 1 0 1 1 1 0 Putative, 10TM heavy-metal exporter DUF5036 PF16439.5 OEU05674.1 - 0.061 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5036) LAP1C PF05609.12 OEU05677.1 - 1.5 7.9 5.4 4.1 6.4 5.4 1.6 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ammonium_transp PF00909.21 OEU05680.1 - 1.9e-16 59.8 4.3 2.2e-16 59.6 4.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_GPL PF05926.11 OEU05681.1 - 0.018 15.0 2.5 0.55 10.2 1.0 2.5 2 0 0 2 2 2 0 Phage head completion protein (GPL) LytTR PF04397.15 OEU05681.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 LytTr DNA-binding domain Tir_receptor_C PF07489.11 OEU05682.1 - 0.053 13.5 4.5 0.083 12.9 4.5 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Nup84_Nup100 PF04121.13 OEU05683.1 - 7.1e-15 54.2 0.3 1e-14 53.6 0.3 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 BT1 PF03092.16 OEU05684.1 - 3.8e-85 286.1 11.6 1.6e-50 171.9 1.0 3.1 1 1 1 2 2 2 2 BT1 family MFS_1_like PF12832.7 OEU05684.1 - 6.2e-06 25.3 6.2 1.1e-05 24.6 6.2 1.3 1 0 0 1 1 1 1 MFS_1 like family PUCC PF03209.15 OEU05684.1 - 2.3e-05 23.6 0.7 0.00017 20.7 0.1 2.2 2 0 0 2 2 2 1 PUCC protein adh_short PF00106.25 OEU05685.1 - 1.2e-23 83.6 0.2 3.6e-14 52.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU05685.1 - 6e-13 48.9 0.2 1.3e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU05685.1 - 0.0084 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OEU05685.1 - 0.032 14.1 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding LSM PF01423.22 OEU05687.1 - 3.3e-14 52.3 0.0 7.1e-14 51.3 0.0 1.5 2 0 0 2 2 2 1 LSM domain VPS13_C PF16909.5 OEU05688.1 - 3.4e-41 141.0 0.2 1.1e-34 119.7 0.0 2.6 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OEU05688.1 - 4.2e-10 39.8 0.0 2.2e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Yae1_N PF09811.9 OEU05689.1 - 0.0029 17.3 32.0 5.9 6.7 0.9 10.1 5 5 5 10 10 10 6 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU05689.1 - 5.2 7.2 60.7 0.12 12.3 19.7 5.4 4 3 1 5 5 5 0 Glycine zipper ATPase-cat_bd PF12156.8 OEU05690.1 - 3.9 8.3 9.6 13 6.6 0.1 3.5 4 0 0 4 4 4 0 Putative metal-binding domain of cation transport ATPase Sulfatase PF00884.23 OEU05691.1 - 2.2e-26 93.0 5.0 3.6e-26 92.3 5.0 1.3 1 0 0 1 1 1 1 Sulfatase IMUP PF15761.5 OEU05691.1 - 0.00091 19.9 6.1 0.15 12.7 1.4 2.3 2 0 0 2 2 2 2 Immortalisation up-regulated protein Dicty_REP PF05086.12 OEU05691.1 - 0.015 13.3 0.4 0.018 13.1 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4976 PF16347.5 OEU05691.1 - 1.8 8.9 6.5 0.27 11.5 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) DUF3439 PF11921.8 OEU05692.1 - 0.16 11.9 7.4 0.25 11.3 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cwf_Cwc_15 PF04889.12 OEU05692.1 - 1.5 8.5 8.0 2.4 7.8 8.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 OEU05692.1 - 2.7 7.3 9.3 3.1 7.2 9.3 1.1 1 0 0 1 1 1 0 SDA1 DDE_Tnp_1 PF01609.21 OEU05694.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain rve PF00665.26 OEU05694.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain CSD PF00313.22 OEU05695.1 - 4.6e-06 26.4 3.7 2.4e-05 24.1 3.7 2.1 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU05695.1 - 0.0036 17.0 1.0 0.035 13.8 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain DUF1983 PF09327.11 OEU05695.1 - 0.14 12.3 1.5 1.8 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1983) RRM_1 PF00076.22 OEU05696.1 - 0.052 13.4 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OEU05698.1 - 2.1e-37 126.8 0.2 2.6e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU05698.1 - 9.8e-06 25.2 0.1 0.0033 17.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OEU05698.1 - 0.00022 20.9 1.1 0.64 9.7 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 OEU05698.1 - 0.00025 21.1 0.0 0.00069 19.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif Rrn6 PF10214.9 OEU05698.1 - 0.41 9.1 4.2 0.51 8.8 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Totivirus_coat PF05518.11 OEU05698.1 - 6.8 4.6 7.1 8.5 4.3 7.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein HA PF03457.14 OEU05699.1 - 1e-57 192.3 5.5 2.6e-19 69.3 0.3 3.1 3 0 0 3 3 3 3 Helicase associated domain Helicase_IV_N PF12462.8 OEU05699.1 - 0.14 12.1 4.0 0.2 11.6 0.6 2.5 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF5624 PF18538.1 OEU05699.1 - 2 8.5 6.0 7.7 6.6 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5624) UBX PF00789.20 OEU05700.1 - 1.1e-12 48.0 0.0 2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain zf-RING_2 PF13639.6 OEU05700.1 - 3.1e-10 40.2 12.8 5.1e-10 39.5 12.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU05700.1 - 6.3e-05 23.2 12.5 0.00016 21.9 12.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU05700.1 - 0.00014 21.8 5.2 0.00014 21.8 5.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU05700.1 - 0.00031 20.5 13.0 0.00069 19.4 13.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU05700.1 - 0.00093 19.0 9.8 0.0015 18.4 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU05700.1 - 0.002 17.9 12.0 0.0032 17.3 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU05700.1 - 0.0037 17.0 8.4 0.0037 17.0 8.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 OEU05700.1 - 0.015 15.2 11.9 0.026 14.5 11.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OEU05700.1 - 0.019 15.0 9.4 0.045 13.8 9.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OEU05700.1 - 0.044 13.6 12.9 0.16 11.9 12.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU05700.1 - 0.046 13.4 10.2 0.1 12.2 10.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SMG1_N PF17229.2 OEU05700.1 - 0.047 14.4 0.3 0.1 13.3 0.3 1.5 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal Ncstrn_small PF18266.1 OEU05700.1 - 0.057 13.4 1.0 0.12 12.4 0.1 2.0 3 0 0 3 3 3 0 Nicastrin small lobe RINGv PF12906.7 OEU05700.1 - 0.3 11.2 9.2 0.66 10.1 9.2 1.6 1 1 0 1 1 1 0 RING-variant domain Rad50_zn_hook PF04423.14 OEU05700.1 - 0.4 10.5 4.6 1 9.2 0.2 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 OEU05700.1 - 0.83 9.9 10.2 3.3 8.0 10.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Nop14 PF04147.12 OEU05701.1 - 4.5 5.4 20.5 6.7 4.8 20.5 1.2 1 0 0 1 1 1 0 Nop14-like family HA PF03457.14 OEU05702.1 - 3.2e-56 187.5 1.5 2.9e-20 72.3 0.1 3.0 3 0 0 3 3 3 3 Helicase associated domain Methyltransf_22 PF13383.6 OEU05702.1 - 0.029 13.9 3.7 0.28 10.7 0.1 2.8 2 1 1 3 3 3 0 Methyltransferase domain DUF3974 PF13120.6 OEU05702.1 - 0.15 12.2 3.5 1.1 9.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3974) DUF1908 PF08926.11 OEU05703.1 - 1.3 8.0 6.0 0.085 11.9 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) SAC3_GANP PF03399.16 OEU05704.1 - 2.3e-47 161.8 0.0 3.7e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family RRM_1 PF00076.22 OEU05705.1 - 3.9e-09 36.2 0.0 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 OEU05706.1 - 1.6e-07 31.3 0.4 7.1e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain TFIIA PF03153.13 OEU05706.1 - 0.12 12.4 8.9 0.15 12.0 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TM_helix PF05552.12 OEU05706.1 - 0.17 11.9 4.6 0.67 10.0 2.5 2.1 2 0 0 2 2 2 0 Conserved TM helix DUF1479 PF07350.12 OEU05707.1 - 4.5e-09 35.6 0.7 4.4e-07 29.0 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 OEU05707.1 - 0.0011 19.2 0.1 0.84 9.8 0.1 2.6 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Nop14 PF04147.12 OEU05707.1 - 0.14 10.3 1.8 0.17 10.1 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4366 PF14283.6 OEU05707.1 - 4.3 7.4 10.3 2.3 8.2 2.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) HA PF03457.14 OEU05708.1 - 9.2e-32 109.2 6.5 9.7e-17 61.1 0.6 2.1 2 0 0 2 2 2 2 Helicase associated domain DUF1803 PF08820.10 OEU05708.1 - 0.00085 19.3 0.3 0.63 10.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1803) IGR PF09597.10 OEU05708.1 - 0.026 14.6 0.8 0.088 12.9 0.8 2.0 1 0 0 1 1 1 0 IGR protein motif DUF1987 PF09345.10 OEU05708.1 - 0.056 13.1 0.8 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) FmdE PF02663.14 OEU05708.1 - 0.068 13.2 1.3 2.5 8.2 0.1 2.1 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF4834 PF16118.5 OEU05711.1 - 1.6 9.7 19.1 4.2 8.4 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF572 PF04502.13 OEU05712.1 - 0.85 9.2 13.3 2.1 7.9 7.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) rve PF00665.26 OEU05713.1 - 1.7e-05 25.0 0.0 0.00036 20.7 0.0 2.4 1 1 1 2 2 2 2 Integrase core domain Retrotran_gag_2 PF14223.6 OEU05714.1 - 0.0086 15.7 5.6 0.058 13.1 0.1 2.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type MnmE_helical PF12631.7 OEU05714.1 - 0.038 14.1 1.3 0.077 13.2 1.3 1.5 1 0 0 1 1 1 0 MnmE helical domain BLOC1_2 PF10046.9 OEU05714.1 - 0.15 12.4 6.3 0.31 11.4 1.3 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PriC PF07445.12 OEU05714.1 - 0.77 9.7 8.2 0.44 10.5 1.9 2.4 1 1 0 2 2 2 0 Primosomal replication protein priC MscS_porin PF12795.7 OEU05714.1 - 1.3 8.5 13.4 0.15 11.6 7.4 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain eIF3_N PF09440.10 OEU05714.1 - 4.9 7.6 9.6 18 5.8 2.6 2.7 2 2 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF1664 PF07889.12 OEU05714.1 - 5.6 7.0 7.1 1.9 8.5 2.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HA PF03457.14 OEU05715.1 - 3e-21 75.5 1.8 3.3e-11 43.3 0.2 2.2 2 0 0 2 2 2 2 Helicase associated domain DUF493 PF04359.14 OEU05716.1 - 3.9e-10 40.2 0.1 9e-10 39.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF493) PBP1_TM PF14812.6 OEU05716.1 - 6.6 7.2 8.0 2.1 8.8 4.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5613 PF18467.1 OEU05717.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5613) Herpes_UL56 PF04534.12 OEU05718.1 - 0.027 14.0 0.4 0.043 13.3 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Bd3614-deam PF14439.6 OEU05718.1 - 3.2 7.8 8.6 17 5.5 0.1 4.1 3 1 1 4 4 4 0 Bd3614-like deaminase DDE_Tnp_1_7 PF13843.6 OEU05719.1 - 6.2e-12 45.5 0.0 9.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Csm1_N PF18504.1 OEU05720.1 - 0.013 15.8 7.0 0.013 15.8 7.0 4.8 1 1 6 7 7 7 0 Csm1 N-terminal domain PI-PLC-X PF00388.19 OEU05720.1 - 5 6.7 10.3 83 2.7 0.0 2.9 2 1 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Macoilin PF09726.9 OEU05720.1 - 6.8 5.1 36.2 9.5 4.6 36.2 1.1 1 0 0 1 1 1 0 Macoilin family PI_PP_I PF18363.1 OEU05720.1 - 8.7 6.6 11.1 12 6.2 1.2 2.8 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DDE_1 PF03184.19 OEU05721.1 - 1.6e-06 27.9 0.2 4.1e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease SMYLE_N PF18615.1 OEU05722.1 - 4.6 6.7 17.3 6.8 6.1 8.6 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain KH_1 PF00013.29 OEU05723.1 - 3.5e-42 142.1 15.1 4.5e-15 55.2 0.3 3.7 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OEU05723.1 - 2.5e-13 49.7 3.7 5.2e-05 23.0 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OEU05723.1 - 3.8e-08 33.0 7.0 0.0037 17.0 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OEU05723.1 - 0.016 15.3 5.6 0.8 9.8 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain SUIM_assoc PF16619.5 OEU05724.1 - 1 9.4 8.3 2.4 8.3 8.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DDE_Tnp_1 PF01609.21 OEU05726.1 - 0.00021 21.0 0.0 0.00068 19.3 0.0 1.8 1 0 0 1 1 1 1 Transposase DDE domain rve PF00665.26 OEU05726.1 - 0.024 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Retrotran_gag_2 PF14223.6 OEU05728.1 - 0.01 15.5 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_27 PF13463.6 OEU05729.1 - 1e-05 25.9 0.0 0.00056 20.4 0.0 2.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain FF PF01846.19 OEU05729.1 - 0.014 15.5 2.0 0.042 14.0 1.3 2.3 2 0 0 2 2 2 0 FF domain Homoserine_dh PF00742.19 OEU05729.1 - 0.016 15.2 0.3 0.032 14.1 0.3 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase DUF4065 PF13274.6 OEU05729.1 - 0.099 13.5 0.6 0.099 13.5 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) RRM_1 PF00076.22 OEU05730.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU05730.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HALZ PF02183.18 OEU05731.1 - 0.00055 20.1 16.1 0.024 14.8 1.8 3.4 3 0 0 3 3 3 2 Homeobox associated leucine zipper TSC22 PF01166.18 OEU05731.1 - 0.0045 17.3 7.3 0.039 14.3 1.1 2.9 1 1 1 2 2 2 2 TSC-22/dip/bun family YabA PF06156.13 OEU05731.1 - 0.0083 16.7 16.3 0.29 11.8 3.6 2.9 1 1 2 3 3 3 2 Initiation control protein YabA Glycoprot_B_PH1 PF17416.2 OEU05731.1 - 0.075 12.7 1.3 0.098 12.3 0.5 1.7 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B Macoilin PF09726.9 OEU05731.1 - 0.086 11.4 13.6 0.12 10.9 13.6 1.2 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 OEU05731.1 - 0.1 10.5 7.2 0.12 10.2 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 OEU05731.1 - 0.25 11.2 11.8 1.4 8.8 1.7 2.9 1 1 1 2 2 2 0 Septum formation initiator MtrG PF04210.13 OEU05733.1 - 2.1 8.2 8.4 6 6.8 0.3 4.1 3 2 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DDE_Tnp_4 PF13359.6 OEU05734.1 - 0.00033 20.4 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2433 PF10360.9 OEU05734.1 - 0.05 13.7 0.1 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) DUF5385 PF17359.2 OEU05736.1 - 0.019 14.6 0.1 0.019 14.6 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5385) CDC45 PF02724.14 OEU05736.1 - 0.024 13.0 9.1 0.017 13.5 3.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.11 OEU05736.1 - 8.7 4.3 11.6 0.49 8.4 0.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen FSIP2 PF15783.5 OEU05737.1 - 0.22 9.4 0.0 0.29 9.0 0.0 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 EamA PF00892.20 OEU05738.1 - 0.0004 20.6 3.9 0.0004 20.6 3.9 3.8 3 1 0 3 3 3 1 EamA-like transporter family DUF4834 PF16118.5 OEU05738.1 - 2.7 9.0 13.5 2.3 9.2 3.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) RXT2_N PF08595.11 OEU05740.1 - 0.0093 16.0 2.5 0.0093 16.0 2.5 2.4 3 0 0 3 3 3 1 RXT2-like, N-terminal DUF1517 PF07466.11 OEU05742.1 - 0.027 14.6 0.1 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) rve PF00665.26 OEU05742.1 - 0.043 14.0 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 Integrase core domain Orthoreo_P10 PF07204.11 OEU05747.1 - 0.0023 17.8 0.3 0.004 17.1 0.3 1.3 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 OEU05747.1 - 0.0047 17.8 0.3 0.082 13.8 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain EVC2_like PF12297.8 OEU05747.1 - 0.011 14.5 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Shisa PF13908.6 OEU05747.1 - 0.011 16.0 2.3 0.011 16.0 2.3 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SARAF PF06682.12 OEU05747.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ETRAMP PF09716.10 OEU05747.1 - 0.096 12.8 0.0 0.096 12.8 0.0 2.6 2 1 0 2 2 1 0 Malarial early transcribed membrane protein (ETRAMP) Tweety PF04906.13 OEU05747.1 - 0.14 10.8 1.2 0.2 10.3 1.2 1.2 1 0 0 1 1 1 0 Tweety FAM176 PF14851.6 OEU05747.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.4 2 1 0 2 2 1 0 FAM176 family LRR19-TM PF15176.6 OEU05747.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.3 2 1 0 2 2 1 0 Leucine-rich repeat family 19 TM domain TMEM52 PF14979.6 OEU05747.1 - 1 9.3 6.6 2.1 8.3 6.6 1.4 1 0 0 1 1 1 0 Transmembrane 52 DUF2208 PF09973.9 OEU05747.1 - 2.4 7.7 3.3 49 3.4 4.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) CDC45 PF02724.14 OEU05747.1 - 7.6 4.7 9.1 4.5 5.5 7.9 1.2 1 1 0 1 1 1 0 CDC45-like protein Asp_protease_2 PF13650.6 OEU05750.1 - 0.0013 19.3 0.0 0.0039 17.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OEU05750.1 - 0.0092 16.5 0.1 0.048 14.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease SUIM_assoc PF16619.5 OEU05752.1 - 0.017 15.1 1.5 0.017 15.1 1.5 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_8 PF13833.6 OEU05752.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Sfi1_C PF10638.9 OEU05753.1 - 0.0046 17.7 0.9 0.016 16.0 0.1 2.4 2 0 0 2 2 2 1 Spindle body associated protein C-terminus DUF2229 PF09989.9 OEU05753.1 - 0.16 11.6 0.2 0.3 10.7 0.2 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) HTH_Tnp_Tc3_2 PF01498.18 OEU05756.1 - 0.11 12.8 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Transposase PhyH PF05721.13 OEU05757.1 - 9.4e-11 42.4 0.0 2.9e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3791 PF12668.7 OEU05757.1 - 0.041 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF285 PF03382.14 OEU05758.1 - 9.7e-173 564.4 67.3 1.5e-37 128.0 4.2 5.3 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 OEU05758.1 - 8.7e-05 22.3 0.6 20 5.1 0.1 5.5 3 1 2 5 5 5 1 DrrA phosphatidylinositol 4-phosphate binding domain DUF1729 PF08354.10 OEU05758.1 - 0.0018 17.3 1.8 5 5.9 0.0 4.0 3 2 1 4 4 4 2 Domain of unknown function (DUF1729) PT PF04886.12 OEU05761.1 - 0.64 9.6 62.0 1.5 8.4 36.8 4.7 4 1 0 4 4 4 0 PT repeat Rep-A_N PF04057.12 OEU05762.1 - 4.6e-09 36.2 0.8 7.7e-09 35.5 0.8 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.9 OEU05762.1 - 0.0059 16.6 0.1 0.022 14.8 0.1 1.9 1 1 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD AAA_lid_7 PF17867.1 OEU05762.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Midasin AAA lid domain DUF3677 PF12432.8 OEU05763.1 - 0.48 10.8 2.8 49 4.3 0.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3677) zf-C2H2_4 PF13894.6 OEU05763.1 - 3.5 8.7 8.1 1.1 10.2 1.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_C48 PF02902.19 OEU05768.1 - 1.7e-11 44.4 0.7 6.2e-11 42.5 0.7 2.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 OEU05768.1 - 0.063 13.7 0.1 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 MULE transposase domain zf-CCHC PF00098.23 OEU05768.1 - 8.3 6.7 14.0 1.4 9.1 8.7 2.6 2 0 0 2 2 2 0 Zinc knuckle Atrophin-1 PF03154.15 OEU05769.1 - 1.1 7.4 5.1 1.3 7.3 5.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family NOA36 PF06524.12 OEU05769.1 - 1.5 8.1 13.1 2 7.7 13.1 1.2 1 0 0 1 1 1 0 NOA36 protein PT PF04886.12 OEU05770.1 - 2.5e-09 36.5 76.8 0.068 12.7 23.5 4.7 1 1 1 2 2 2 1 PT repeat DUF4820 PF16091.5 OEU05772.1 - 0.27 10.6 4.7 0.4 10.0 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NAD_binding_10 PF13460.6 OEU05773.1 - 9.2e-10 38.7 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OEU05773.1 - 2.9e-05 24.5 0.0 5.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OEU05773.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU05773.1 - 0.011 14.9 0.0 0.035 13.2 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 OEU05773.1 - 0.025 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OEU05773.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OEU05773.1 - 0.043 13.9 0.0 0.081 13.1 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 OEU05773.1 - 0.069 13.7 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OEU05773.1 - 0.083 11.9 0.5 0.43 9.5 0.5 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4064 PF13273.6 OEU05774.1 - 0.0054 17.0 1.0 0.0079 16.5 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Mucin PF01456.17 OEU05774.1 - 0.0087 16.1 4.3 0.0087 16.1 4.3 2.1 2 0 0 2 2 2 2 Mucin-like glycoprotein BAT2_N PF07001.11 OEU05774.1 - 0.079 13.4 2.7 0.3 11.5 0.4 2.1 2 0 0 2 2 2 0 BAT2 N-terminus Candida_ALS PF05792.13 OEU05774.1 - 4.1 8.1 41.5 1.2 9.8 22.8 2.8 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) SSP160 PF06933.11 OEU05774.1 - 5.9 5.0 26.9 0.74 7.9 6.5 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF4512 PF14975.6 OEU05774.1 - 6.4 7.6 10.3 2.5 8.9 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DDE_Tnp_1_7 PF13843.6 OEU05776.1 - 5.9e-18 65.3 0.1 8.7e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 STELLO PF03385.17 OEU05777.1 - 1.6e-08 33.8 0.0 2.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases Glyco_tranf_2_4 PF13704.6 OEU05777.1 - 2.1e-05 25.0 0.0 5.9e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 SLAIN PF15301.6 OEU05778.1 - 0.0085 15.4 1.8 0.0085 15.4 1.8 2.1 2 0 0 2 2 2 1 SLAIN motif-containing family BHD_2 PF10404.9 OEU05779.1 - 0.19 12.7 3.1 0.79 10.7 0.0 3.1 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 2 Gastrin PF00918.17 OEU05781.1 - 2.5 9.1 6.3 13 6.8 1.6 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Uso1_p115_C PF04871.13 OEU05781.1 - 2.6 8.4 18.1 0.14 12.5 7.7 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PTPlike_phytase PF14566.6 OEU05781.1 - 7.3 6.7 10.5 0.62 10.2 3.6 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Macoilin PF09726.9 OEU05783.1 - 0.76 8.3 15.4 0.91 8.0 15.4 1.2 1 0 0 1 1 1 0 Macoilin family Dirigent PF03018.14 OEU05784.1 - 0.0077 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Dirigent-like protein OB_NTP_bind PF07717.16 OEU05785.1 - 5e-20 71.6 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OEU05785.1 - 2.4e-18 66.4 0.0 6.7e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OEU05785.1 - 2.4e-16 60.1 0.0 6.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU05785.1 - 2.5e-06 27.4 0.2 4.8e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OEU05785.1 - 0.016 15.6 0.1 0.037 14.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OEU05785.1 - 0.017 14.6 0.4 0.037 13.5 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 OEU05785.1 - 0.042 14.1 1.1 1.1 9.5 2.4 2.6 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 OEU05785.1 - 0.091 12.7 0.2 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 OEU05785.1 - 0.11 12.5 1.2 1.5 8.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OEU05785.1 - 0.11 13.0 0.1 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Cullin_Nedd8 PF10557.9 OEU05785.1 - 0.17 11.9 3.0 0.19 11.8 0.1 2.5 3 0 0 3 3 3 0 Cullin protein neddylation domain ResIII PF04851.15 OEU05785.1 - 0.2 11.6 1.5 3.1 7.8 0.4 3.2 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit 2_5_RNA_ligase2 PF13563.6 OEU05786.1 - 9e-08 32.2 0.0 3.4e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Ribosomal_60s PF00428.19 OEU05788.1 - 0.071 13.7 1.9 0.27 11.9 1.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRM_1 PF00076.22 OEU05789.1 - 1.5e-16 60.0 0.0 1.7e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3464 PF11947.8 OEU05790.1 - 0.049 13.4 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CRA PF06589.11 OEU05791.1 - 0.024 14.7 2.0 0.024 14.7 2.0 1.7 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) NARP1 PF12569.8 OEU05791.1 - 0.84 8.5 5.8 1.1 8.1 5.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Band_3_cyto PF07565.13 OEU05792.1 - 0.097 12.5 1.7 0.13 12.1 1.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF5101 PF17031.5 OEU05792.1 - 0.49 10.5 3.5 4.9 7.3 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5101) MtN3_slv PF03083.16 OEU05793.1 - 5.6e-27 93.6 9.4 7.5e-18 64.4 2.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Menin PF05053.13 OEU05793.1 - 0.0047 15.4 2.0 0.0065 14.9 2.0 1.3 1 0 0 1 1 1 1 Menin RIFIN PF02009.16 OEU05793.1 - 0.23 11.3 2.1 0.36 10.7 2.1 1.2 1 0 0 1 1 1 0 Rifin NINJA_B PF16136.5 OEU05793.1 - 1.3 9.4 6.3 2.2 8.7 6.3 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal SR-25 PF10500.9 OEU05793.1 - 2.1 7.9 5.5 4.5 6.8 5.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fasciclin PF02469.22 OEU05795.1 - 8.4e-10 39.0 0.6 8.4e-10 39.0 0.6 2.9 3 2 0 3 3 3 1 Fasciclin domain PseudoU_synth_2 PF00849.22 OEU05797.1 - 1.3e-25 90.3 0.0 2.8e-25 89.3 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_2 PF00849.22 OEU05799.1 - 7.1e-15 55.4 0.1 1.4e-14 54.5 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OEU05799.1 - 1.5e-06 27.8 0.2 4.9e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 S4 domain AMP-binding PF00501.28 OEU05801.1 - 1.3e-92 310.6 0.0 1.8e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PQ-loop PF04193.14 OEU05802.1 - 1.2e-33 114.6 16.3 1.9e-18 66.0 2.5 3.7 4 0 0 4 4 4 2 PQ loop repeat Rrp15p PF07890.12 OEU05803.1 - 8.4e-24 84.4 4.2 8.4e-24 84.4 4.2 2.8 3 1 0 3 3 3 1 Rrp15p zf-C3HC4 PF00097.25 OEU05804.1 - 6.2e-09 35.6 8.2 1.2e-08 34.6 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU05804.1 - 1.3e-07 31.8 8.7 2.3e-07 31.0 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU05804.1 - 2.1e-07 30.7 8.3 2.1e-07 30.7 8.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU05804.1 - 3.1e-07 30.3 1.9 3.1e-07 30.3 1.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU05804.1 - 9.2e-07 28.9 3.5 2.5e-06 27.5 3.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OEU05804.1 - 1.6e-06 27.8 11.1 1e-05 25.2 11.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU05804.1 - 1.8e-05 24.6 9.0 1.8e-05 24.6 9.0 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OEU05804.1 - 6.6e-05 22.7 4.6 0.00014 21.6 4.6 1.6 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OEU05804.1 - 8.2e-05 22.4 7.1 0.00028 20.7 7.1 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_PP31 PF05311.11 OEU05804.1 - 0.0005 19.6 5.5 0.00058 19.4 5.5 1.1 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) Baculo_IE-1 PF05290.11 OEU05804.1 - 0.0042 17.0 0.8 0.0057 16.6 0.8 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Nucleo_P87 PF07267.11 OEU05804.1 - 0.014 14.2 5.9 0.019 13.8 5.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-Nse PF11789.8 OEU05804.1 - 0.019 14.8 2.4 0.036 13.9 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OEU05804.1 - 0.067 13.0 5.8 0.18 11.6 5.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OEU05804.1 - 0.095 12.5 2.7 0.41 10.4 2.8 2.0 1 1 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 OEU05804.1 - 0.1 12.9 9.0 0.37 11.1 9.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain UPF0547 PF10571.9 OEU05804.1 - 0.13 12.4 1.1 0.13 12.4 1.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 OEU05804.1 - 0.18 12.0 5.3 5.5 7.2 1.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_10 PF16685.5 OEU05804.1 - 0.61 10.3 10.2 0.41 10.8 7.9 2.0 2 1 0 2 2 2 0 zinc RING finger of MSL2 HA PF03457.14 OEU05805.1 - 2.7e-58 194.2 4.7 5.6e-20 71.4 0.2 3.1 3 0 0 3 3 3 3 Helicase associated domain IstB_IS21_ATP PF08483.11 OEU05805.1 - 0.0058 16.5 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding N-terminal TRADD_N PF09034.10 OEU05805.1 - 0.057 13.5 0.0 4.9 7.2 0.0 2.9 3 0 0 3 3 3 0 TRADD, N-terminal domain Peptidase_M15_4 PF13539.6 OEU05805.1 - 0.078 13.5 1.4 3.5 8.2 0.0 3.0 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase PKcGMP_CC PF16808.5 OEU05805.1 - 0.25 11.3 6.4 0.36 10.7 0.5 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase C1-set PF07654.15 OEU05805.1 - 0.28 11.6 2.7 19 5.7 0.1 2.8 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Phage_lysozyme2 PF18013.1 OEU05805.1 - 2.8 7.9 12.8 1.1e+04 -3.7 12.8 3.1 1 1 0 1 1 1 0 Phage tail lysozyme IR1-M PF12185.8 OEU05807.1 - 0.042 13.8 0.9 0.067 13.1 0.9 1.3 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DDE_Tnp_1_7 PF13843.6 OEU05808.1 - 9.7e-17 61.3 0.1 1.7e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 Transposase IS4 C2 PF00168.30 OEU05809.1 - 8.7e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Reticulon PF02453.17 OEU05809.1 - 0.039 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Reticulon HemY_N PF07219.13 OEU05809.1 - 0.064 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus DUF3494 PF11999.8 OEU05810.1 - 1.6e-54 184.7 17.1 1.9e-54 184.5 17.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Arg_decarb_HB PF17810.1 OEU05810.1 - 0.22 11.8 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain Sortilin-Vps10 PF15902.5 OEU05811.1 - 4e-06 25.9 0.0 0.00055 18.8 0.0 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 OEU05811.1 - 0.0002 20.8 1.1 0.01 15.2 0.1 3.0 2 1 1 3 3 3 1 BNR repeat-like domain DUF1256 PF06866.11 OEU05811.1 - 0.00068 19.1 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1256) BNR PF02012.20 OEU05811.1 - 0.00088 18.9 21.5 0.45 10.7 0.4 5.4 4 0 0 4 4 4 3 BNR/Asp-box repeat DUF4185 PF13810.6 OEU05811.1 - 0.0089 15.3 1.1 13 4.9 0.3 3.8 2 1 0 3 3 3 2 Domain of unknown function (DUF4185) BNR_3 PF13859.6 OEU05811.1 - 0.014 14.7 0.4 10 5.3 0.0 3.2 2 1 1 3 3 3 0 BNR repeat-like domain BNR_6 PF15899.5 OEU05811.1 - 0.048 13.7 0.1 0.048 13.7 0.1 4.2 4 0 0 4 4 4 0 BNR-Asp box repeat AUX_IAA PF02309.16 OEU05812.1 - 0.088 12.6 0.1 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 AUX/IAA family WHIM1 PF15612.6 OEU05813.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 US6 PF17616.2 OEU05813.1 - 0.12 12.3 1.1 0.24 11.4 1.1 1.4 1 0 0 1 1 1 0 Viral unique short region 6 Mitofilin PF09731.9 OEU05816.1 - 1e-32 113.8 1.4 1.2e-32 113.6 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein WHEP-TRS PF00458.20 OEU05816.1 - 0.0031 17.6 3.3 1.2 9.3 0.5 2.4 2 0 0 2 2 2 2 WHEP-TRS domain YCII PF03795.14 OEU05817.1 - 0.04 14.3 0.0 0.046 14.1 0.0 1.1 1 0 0 1 1 1 0 YCII-related domain CCDC53 PF10152.9 OEU05819.1 - 0.078 13.4 0.1 0.25 11.8 0.1 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Med21 PF11221.8 OEU05819.1 - 0.1 12.8 1.2 2 8.7 0.1 2.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Caleosin PF05042.13 OEU05819.1 - 0.11 12.5 0.1 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein Spectrin PF00435.21 OEU05819.1 - 1.4 9.4 5.7 5.6 7.5 0.1 4.1 3 1 0 4 4 4 0 Spectrin repeat CLZ PF16526.5 OEU05819.1 - 3.4 8.1 5.5 35 4.9 0.0 3.9 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 OEU05819.1 - 5.3 7.4 8.4 13 6.1 0.4 4.1 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MTHFR_C PF12225.8 OEU05820.1 - 0.54 9.9 3.6 0.62 9.7 2.0 1.9 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Zn_clus PF00172.18 OEU05820.1 - 2.4 8.3 6.1 5.4 7.2 6.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 OEU05822.1 - 0.0072 16.6 4.2 0.0072 16.6 4.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU05822.1 - 0.059 13.2 3.5 0.12 12.3 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OEU05823.1 - 3.7e-18 65.8 0.0 4.2e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain OxoDH_E1alpha_N PF12573.8 OEU05824.1 - 0.1 12.4 0.4 0.27 11.0 0.4 1.7 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF2873 PF11395.8 OEU05825.1 - 8.4 6.3 8.9 12 5.8 8.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2873) zf-RVT PF13966.6 OEU05826.1 - 5.8e-05 23.7 1.1 5.8e-05 23.7 1.1 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF3319 PF11782.8 OEU05826.1 - 0.012 15.6 0.3 0.039 13.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) RVT_1 PF00078.27 OEU05827.1 - 0.00034 20.2 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Seryl_tRNA_N PF02403.22 OEU05828.1 - 0.012 15.9 13.0 0.22 11.8 0.4 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 OEU05828.1 - 0.018 15.1 2.9 0.018 15.1 2.9 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT20 PF14931.6 OEU05828.1 - 0.023 14.9 7.1 0.39 10.9 0.6 2.6 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF745 PF05335.13 OEU05828.1 - 0.23 11.2 11.3 0.24 11.1 6.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DivIC PF04977.15 OEU05828.1 - 0.37 10.6 0.1 0.37 10.6 0.1 4.2 4 1 1 5 5 5 0 Septum formation initiator DUF1664 PF07889.12 OEU05828.1 - 0.59 10.2 6.2 6.1 6.9 0.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 OEU05828.1 - 0.91 10.3 5.7 2.9 8.7 0.1 3.1 1 1 2 3 3 3 0 Occludin homology domain DUF948 PF06103.11 OEU05828.1 - 1.6 9.0 5.6 7.5 6.9 0.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) SURF2 PF05477.11 OEU05828.1 - 5 6.7 11.7 1.6 8.4 4.1 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) zf-RVT PF13966.6 OEU05829.1 - 0.00016 22.3 0.7 0.00016 22.3 0.7 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 OEU05829.1 - 0.0027 17.9 0.0 0.0085 16.3 0.0 1.8 1 0 0 1 1 1 1 RNase H DUF3319 PF11782.8 OEU05829.1 - 0.043 13.8 0.3 0.13 12.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) RVT_1 PF00078.27 OEU05830.1 - 0.00023 20.7 0.1 0.0035 16.9 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) USP8_interact PF08941.10 OEU05830.1 - 3.5 7.4 8.1 12 5.6 8.1 2.0 1 0 0 1 1 1 0 USP8 interacting Dus PF01207.17 OEU05835.1 - 1.9e-47 161.9 0.0 2.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Glu_synthase PF01645.17 OEU05836.1 - 5.7e-11 42.2 0.2 5.7e-11 42.2 0.2 1.0 1 0 0 1 1 1 1 Conserved region in glutamate synthase SQS_PSY PF00494.19 OEU05837.1 - 6.1e-34 117.7 0.0 9.8e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase SH3_5 PF08460.10 OEU05838.1 - 0.075 13.1 0.2 1.5 9.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain SWM_repeat PF13753.6 OEU05838.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative flagellar system-associated repeat PAF-AH_p_II PF03403.13 OEU05839.1 - 3.5e-16 58.7 4.9 4.2e-06 25.5 0.0 3.5 3 1 1 4 4 4 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OEU05839.1 - 1.1e-05 24.4 0.4 6.2e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF676 PF05057.14 OEU05839.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 OEU05839.1 - 0.012 15.3 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OEU05839.1 - 0.023 14.6 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 OEU05839.1 - 0.068 12.4 0.9 1.3 8.3 0.6 2.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 IL1_propep PF02394.16 OEU05839.1 - 0.088 13.7 1.6 0.33 11.9 1.6 2.0 1 0 0 1 1 1 0 Interleukin-1 propeptide Chlorophyllase PF07224.11 OEU05839.1 - 0.093 11.7 0.6 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_6 PF12697.7 OEU05839.1 - 0.1 13.2 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 OEU05839.1 - 0.15 12.1 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain DUF3439 PF11921.8 OEU05839.1 - 9.7 6.2 9.3 32 4.5 9.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Adeno_PV PF03910.13 OEU05840.1 - 0.0066 15.2 12.2 0.23 10.1 4.6 2.3 2 0 0 2 2 2 2 Adenovirus minor core protein PV TFIIF_alpha PF05793.12 OEU05840.1 - 0.026 13.1 32.2 0.041 12.5 32.2 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.9 OEU05840.1 - 0.13 11.8 36.1 0.3 10.7 15.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3807 PF12720.7 OEU05840.1 - 0.14 12.4 29.8 1.1 9.5 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) AP3D1 PF06375.11 OEU05840.1 - 1.2 9.4 37.7 3 8.1 20.0 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SUI1 PF01253.22 OEU05841.1 - 2.4e-06 28.0 0.0 5.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Med6 PF04934.14 OEU05841.1 - 0.0013 18.5 0.2 0.0035 17.1 0.1 1.7 2 0 0 2 2 2 1 MED6 mediator sub complex component DUF4266 PF14086.6 OEU05842.1 - 0.018 16.0 0.9 0.018 16.0 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4266) FYDLN_acid PF09538.10 OEU05842.1 - 0.86 10.3 8.3 1.1 9.9 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2457 PF10446.9 OEU05842.1 - 1.2 8.2 7.6 1.3 8.0 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fasciclin PF02469.22 OEU05843.1 - 3.4e-21 75.8 0.0 3.8e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain DUF4993 PF16384.5 OEU05843.1 - 0.18 10.8 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Fasciclin PF02469.22 OEU05844.1 - 6.5e-28 97.5 0.0 7.4e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 OEU05845.1 - 2.9e-56 189.2 1.2 7.4e-28 97.3 0.2 2.0 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 OEU05846.1 - 3.5e-27 95.1 0.0 4e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 OEU05847.1 - 6.1e-59 197.8 1.1 1.6e-29 102.7 0.5 2.1 2 0 0 2 2 2 2 Fasciclin domain Phage-scaffold PF09306.10 OEU05848.1 - 0.021 14.2 0.7 0.027 13.9 0.7 1.3 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein DUF4274 PF14096.6 OEU05848.1 - 0.038 14.0 0.6 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) AAA_34 PF13872.6 OEU05850.1 - 8.8e-68 228.4 0.0 4.5e-67 226.1 0.0 2.0 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 OEU05850.1 - 1.4e-12 47.9 0.0 4.3e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue Glyco_tranf_2_4 PF13704.6 OEU05851.1 - 0.00014 22.3 3.5 0.007 16.9 3.4 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 2 Methyltransf_12 PF08242.12 OEU05851.1 - 0.012 16.4 0.9 0.16 12.7 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain ECSIT_C PF14784.6 OEU05851.1 - 2.6 8.4 7.1 1.5 9.1 0.1 2.8 2 1 0 2 2 2 0 C-terminal domain of the ECSIT protein BNR_3 PF13859.6 OEU05854.1 - 0.18 11.1 5.8 0.04 13.2 0.9 2.1 2 1 0 2 2 2 0 BNR repeat-like domain FMN_red PF03358.15 OEU05855.1 - 2e-24 86.1 0.0 4.7e-24 84.9 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase CarS-like PF01864.17 OEU05855.1 - 0.23 11.4 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 CDP-archaeol synthase AreA_N PF07573.11 OEU05856.1 - 0.14 12.8 1.4 0.68 10.6 0.4 2.5 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus DUF572 PF04502.13 OEU05856.1 - 3.8 7.0 18.8 1 8.9 6.8 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF572) YL1 PF05764.13 OEU05857.1 - 1.8 8.6 11.0 0.64 10.1 0.5 2.3 2 0 0 2 2 2 0 YL1 nuclear protein AF-4 PF05110.13 OEU05859.1 - 0.13 10.4 9.1 0.13 10.4 9.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 OEU05860.1 - 0.64 8.2 4.6 0.71 8.1 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Amidohydro_1 PF01979.20 OEU05861.1 - 2.9e-48 164.9 1.9 3.3e-48 164.8 1.9 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OEU05861.1 - 1.6e-13 50.9 0.6 1e-09 38.4 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family Pterin_bind PF00809.22 OEU05861.1 - 0.055 13.1 0.5 0.083 12.6 0.5 1.3 1 0 0 1 1 1 0 Pterin binding enzyme DUF3819 PF12842.7 OEU05862.1 - 9.7e-37 126.1 2.0 1.1e-36 126.0 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Dioxygenase_C PF00775.21 OEU05863.1 - 7.8e-13 48.3 0.7 2.6e-11 43.3 0.7 2.1 1 1 0 1 1 1 1 Dioxygenase VKG_Carbox PF05090.14 OEU05865.1 - 1.3e-10 40.7 14.5 1.9e-10 40.2 14.5 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase UAF_Rrn10 PF05234.11 OEU05866.1 - 0.38 11.0 0.9 3.3 8.0 0.0 2.8 3 1 1 4 4 4 0 UAF complex subunit Rrn10 DUF4460 PF14687.6 OEU05868.1 - 0.092 12.8 1.6 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) CpXC PF14353.6 OEU05871.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 CpXC protein SR-25 PF10500.9 OEU05871.1 - 0.55 9.8 7.1 0.32 10.6 2.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 OEU05871.1 - 2 7.1 4.1 2.5 6.8 4.1 1.1 1 0 0 1 1 1 0 Presenilin DUF5633 PF18656.1 OEU05874.1 - 0.0033 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5633) DUF4235 PF14019.6 OEU05875.1 - 0.011 15.7 0.3 0.022 14.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Antimicrobial_1 PF08018.11 OEU05875.1 - 8.9 6.6 5.8 6.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide UPF0524 PF15823.5 OEU05876.1 - 0.21 11.0 5.8 0.59 9.5 5.8 1.9 1 1 0 1 1 1 0 UPF0524 of C3orf70 DUF3810 PF12725.7 OEU05877.1 - 0.1 11.9 0.3 0.18 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ARF7EP_C PF14949.6 OEU05882.1 - 0.024 15.3 0.7 0.024 15.3 0.7 5.6 4 2 1 5 5 5 0 ARF7 effector protein C-terminus Spore_coat_CotO PF14153.6 OEU05882.1 - 3.9 7.3 46.7 0.035 14.0 7.6 3.9 4 0 0 4 4 4 0 Spore coat protein CotO CPBP PF02517.16 OEU05883.1 - 5.4e-09 36.3 0.7 2e-08 34.5 0.7 2.0 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease B_lectin PF01453.24 OEU05883.1 - 0.16 12.6 5.0 1.2 9.7 0.2 3.5 3 0 0 3 3 3 0 D-mannose binding lectin Cytochrom_B562 PF07361.11 OEU05884.1 - 0.016 15.9 0.3 1.3 9.7 0.0 2.9 3 0 0 3 3 3 0 Cytochrome b562 DUF4834 PF16118.5 OEU05884.1 - 0.27 12.2 2.5 1.7 9.7 2.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF365 PF04033.12 OEU05885.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Methyltransf_24 PF13578.6 OEU05886.1 - 0.011 16.7 0.0 0.031 15.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Cation_ATPase PF13246.6 OEU05887.1 - 3.8e-06 26.9 0.0 2.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OEU05887.1 - 4.4e-06 27.1 0.3 4.2e-05 23.9 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 OEU05887.1 - 0.00016 21.3 0.5 0.00035 20.2 0.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 OEU05887.1 - 0.015 14.8 0.7 0.1 12.1 0.0 2.5 2 1 0 2 2 2 0 E1-E2 ATPase SpoIIP PF07454.11 OEU05888.1 - 0.00026 20.6 3.4 0.00026 20.6 3.4 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) UPF0565 PF10561.9 OEU05888.1 - 0.0007 18.9 3.2 0.00072 18.9 3.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 DDHD PF02862.17 OEU05888.1 - 0.001 19.3 4.9 0.001 19.3 4.9 1.0 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 OEU05888.1 - 0.0027 17.8 23.8 0.003 17.6 23.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 OEU05888.1 - 0.003 17.4 3.7 0.0031 17.4 3.7 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain EPL1 PF10513.9 OEU05888.1 - 0.0032 17.9 6.9 0.0036 17.7 6.9 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like CobT PF06213.12 OEU05888.1 - 0.0041 16.6 8.7 0.0044 16.5 8.7 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CD20 PF04103.15 OEU05888.1 - 0.0054 16.8 0.2 0.008 16.3 0.2 1.3 1 0 0 1 1 1 1 CD20-like family PPL5 PF18168.1 OEU05888.1 - 0.0055 16.0 1.9 0.0059 15.9 1.9 1.1 1 0 0 1 1 1 1 Prim-pol family 5 RskA PF10099.9 OEU05888.1 - 0.0056 17.0 2.8 0.0064 16.8 2.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Connexin PF00029.19 OEU05888.1 - 0.0078 16.0 4.0 0.0091 15.8 4.0 1.2 1 0 0 1 1 1 1 Connexin DUF913 PF06025.12 OEU05888.1 - 0.009 15.0 1.2 0.0093 15.0 1.2 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 OEU05888.1 - 0.0091 15.4 6.0 0.011 15.1 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) Androgen_recep PF02166.16 OEU05888.1 - 0.0093 14.9 20.4 0.011 14.6 20.4 1.3 1 0 0 1 1 1 1 Androgen receptor Folliculin PF11704.8 OEU05888.1 - 0.0099 15.8 3.5 0.011 15.7 3.5 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2126 PF09899.9 OEU05888.1 - 0.011 13.8 1.8 0.011 13.9 1.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) AIF_C PF14721.6 OEU05888.1 - 0.012 16.0 3.7 0.015 15.7 3.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIP5K PF01504.18 OEU05888.1 - 0.013 14.8 2.9 0.013 14.7 2.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Podoplanin PF05808.11 OEU05888.1 - 0.015 15.4 0.2 0.025 14.7 0.2 1.3 1 0 0 1 1 1 0 Podoplanin Rxt3 PF08642.10 OEU05888.1 - 0.016 16.0 1.5 0.019 15.7 1.5 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Ureide_permease PF07168.11 OEU05888.1 - 0.017 13.9 1.4 0.018 13.8 1.4 1.1 1 0 0 1 1 1 0 Ureide permease V_ATPase_I PF01496.19 OEU05888.1 - 0.02 12.8 7.3 0.022 12.7 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 OEU05888.1 - 0.023 14.4 2.5 0.029 14.0 2.5 1.2 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.16 OEU05888.1 - 0.024 14.7 2.8 0.022 14.8 2.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pannexin_like PF12534.8 OEU05888.1 - 0.025 13.7 4.4 0.026 13.6 4.4 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF5568 PF17724.1 OEU05888.1 - 0.026 14.3 3.8 0.03 14.1 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5568) Med15 PF09606.10 OEU05888.1 - 0.028 13.1 21.9 0.031 13.0 21.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GOLD_2 PF13897.6 OEU05888.1 - 0.029 14.9 0.1 0.035 14.6 0.1 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking TRM13 PF05206.14 OEU05888.1 - 0.035 13.6 10.0 0.041 13.4 10.0 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 SLC12 PF03522.15 OEU05888.1 - 0.035 13.1 7.4 0.036 13.1 7.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4228 PF14009.6 OEU05888.1 - 0.037 14.4 2.1 0.039 14.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Spt20 PF12090.8 OEU05888.1 - 0.044 13.4 38.1 0.063 12.9 38.1 1.2 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 OEU05888.1 - 0.047 14.3 14.5 0.058 14.1 14.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.6 OEU05888.1 - 0.055 13.5 6.7 0.073 13.1 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A G0-G1_switch_2 PF15103.6 OEU05888.1 - 0.058 13.8 6.7 0.097 13.1 6.7 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 FHIPEP PF00771.20 OEU05888.1 - 0.062 11.8 5.1 0.072 11.6 5.1 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2722 PF10846.8 OEU05888.1 - 0.073 12.0 26.8 0.086 11.8 26.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 OEU05888.1 - 0.1 11.6 14.6 0.11 11.5 14.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 OEU05888.1 - 0.11 10.5 8.9 0.13 10.4 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3408 PF11888.8 OEU05888.1 - 0.11 12.6 9.8 0.14 12.3 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Velvet PF11754.8 OEU05888.1 - 0.11 12.4 9.1 0.12 12.2 9.1 1.1 1 0 0 1 1 1 0 Velvet factor Serinc PF03348.15 OEU05888.1 - 0.11 11.3 7.0 0.15 10.9 7.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paf1 PF03985.13 OEU05888.1 - 0.13 11.2 9.3 0.15 11.0 9.3 1.0 1 0 0 1 1 1 0 Paf1 O-antigen_lig PF13425.6 OEU05888.1 - 0.14 10.9 1.2 0.16 10.7 1.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pex26 PF07163.12 OEU05888.1 - 0.15 11.4 8.0 0.17 11.2 8.0 1.1 1 0 0 1 1 1 0 Pex26 protein DUF4199 PF13858.6 OEU05888.1 - 0.15 12.4 0.7 0.16 12.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Otopetrin PF03189.13 OEU05888.1 - 0.16 10.8 3.2 0.16 10.7 3.2 1.1 1 0 0 1 1 1 0 Otopetrin EMC3_TMCO1 PF01956.16 OEU05888.1 - 0.16 11.7 5.2 0.18 11.5 5.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4834 PF16118.5 OEU05888.1 - 0.17 12.8 13.7 0.29 12.1 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) YABBY PF04690.13 OEU05888.1 - 0.19 12.3 9.6 0.24 11.9 9.6 1.1 1 0 0 1 1 1 0 YABBY protein Presenilin PF01080.17 OEU05888.1 - 0.19 10.4 12.7 0.24 10.1 12.7 1.1 1 0 0 1 1 1 0 Presenilin PepSY_TM PF03929.16 OEU05888.1 - 0.21 11.2 2.6 0.23 11.1 2.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM region SID-1_RNA_chan PF13965.6 OEU05888.1 - 0.21 9.9 2.5 0.25 9.7 2.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HCO3_cotransp PF00955.21 OEU05888.1 - 0.24 10.2 1.6 0.23 10.2 1.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF3371 PF11851.8 OEU05888.1 - 0.24 12.5 10.6 0.31 12.2 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF775 PF05603.12 OEU05888.1 - 0.24 10.9 14.3 0.32 10.5 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF3405 PF11885.8 OEU05888.1 - 0.24 9.9 9.4 0.28 9.7 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) RR_TM4-6 PF06459.12 OEU05888.1 - 0.27 11.0 11.0 0.32 10.8 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 API5 PF05918.11 OEU05888.1 - 0.29 9.9 13.8 0.35 9.6 13.8 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ABC2_membrane_2 PF12679.7 OEU05888.1 - 0.32 10.2 1.3 0.35 10.1 1.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.14 OEU05888.1 - 0.32 10.9 13.9 0.37 10.7 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Plasmodium_Vir PF05795.11 OEU05888.1 - 0.39 10.1 5.9 0.41 10.0 5.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LIM_bind PF01803.16 OEU05888.1 - 0.4 10.2 10.0 0.48 9.9 10.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein CPSF100_C PF13299.6 OEU05888.1 - 0.41 10.8 10.1 0.51 10.5 10.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 OEU05888.1 - 0.44 9.5 7.0 0.5 9.4 7.0 1.1 1 0 0 1 1 1 0 CLN3 protein Ocular_alb PF02101.15 OEU05888.1 - 0.44 9.4 2.8 0.52 9.2 2.8 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein TMEM51 PF15345.6 OEU05888.1 - 0.46 10.3 9.3 0.53 10.1 9.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mem_trans PF03547.18 OEU05888.1 - 0.51 8.7 1.9 0.59 8.5 1.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.10 OEU05888.1 - 0.6 8.7 10.1 0.69 8.5 10.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EIIBC-GUT_N PF03612.14 OEU05888.1 - 0.72 9.6 11.9 0.89 9.3 11.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Hid1 PF12722.7 OEU05888.1 - 0.77 7.8 9.3 0.86 7.6 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CSG2 PF16965.5 OEU05888.1 - 0.92 8.4 5.3 1.1 8.1 5.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 OEU05888.1 - 0.92 8.3 7.8 1.1 8.0 7.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TERB2 PF15101.6 OEU05888.1 - 0.96 9.5 17.4 1.3 9.1 17.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 OEU05888.1 - 1 7.5 18.4 1.2 7.3 18.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec62 PF03839.16 OEU05888.1 - 1.3 8.5 10.0 1.7 8.1 10.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 OATP PF03137.20 OEU05888.1 - 1.3 7.2 5.0 1.5 7.0 5.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CBP_BcsG PF11658.8 OEU05888.1 - 1.4 7.2 8.9 1.6 7.0 8.9 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Kei1 PF08552.11 OEU05888.1 - 1.4 8.8 8.8 0.2 11.5 5.5 1.4 2 0 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 NEMP PF10225.9 OEU05888.1 - 1.5 8.4 4.8 1.9 8.1 4.8 1.2 1 0 0 1 1 1 0 NEMP family TMEM208_SND2 PF05620.11 OEU05888.1 - 1.6 8.5 8.7 2.7 7.7 8.7 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 GREB1 PF15782.5 OEU05888.1 - 1.7 5.7 11.1 1.8 5.6 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Folate_carrier PF01770.18 OEU05888.1 - 1.7 7.3 6.8 2.1 7.0 6.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier Baculo_PP31 PF05311.11 OEU05888.1 - 2 7.8 12.6 2.4 7.6 12.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DivIC PF04977.15 OEU05888.1 - 2.1 8.2 17.5 3.6 7.4 17.5 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF2367 PF10164.9 OEU05888.1 - 2.1 8.9 6.0 3.2 8.3 6.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Ctr PF04145.15 OEU05888.1 - 2.4 8.8 6.5 3.2 8.4 6.5 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Membralin PF09746.9 OEU05888.1 - 2.5 7.0 6.5 2.9 6.8 6.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF5349 PF17298.2 OEU05888.1 - 2.8 7.6 16.0 2.9 7.5 16.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Tim54 PF11711.8 OEU05888.1 - 3.3 6.4 12.3 3.9 6.2 12.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1980 PF09323.10 OEU05888.1 - 3.8 7.4 8.9 5.7 6.8 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RNA_pol_Rbc25 PF08292.12 OEU05888.1 - 3.9 7.7 9.7 5.4 7.3 9.7 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 MMR1 PF08505.10 OEU05888.1 - 4.3 7.5 16.6 5.3 7.2 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UPF0560 PF10577.9 OEU05888.1 - 5.8 5.3 18.3 6.6 5.1 18.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NST1 PF13945.6 OEU05888.1 - 6.7 6.8 22.7 9.4 6.3 22.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4770 PF15994.5 OEU05888.1 - 8.3 6.6 14.9 13 6.0 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF3464 PF11947.8 OEU05888.1 - 8.4 6.1 12.8 12 5.6 12.8 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-RING_5 PF14634.6 OEU05891.1 - 0.0027 17.6 10.8 0.0063 16.5 10.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU05891.1 - 0.094 12.6 13.3 0.35 10.8 13.3 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU05891.1 - 0.4 11.1 14.2 0.11 12.8 10.5 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 OEU05891.1 - 0.55 10.1 8.2 1 9.3 6.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU05891.1 - 0.83 9.6 11.6 2 8.3 11.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU05891.1 - 4 7.4 15.8 0.43 10.5 10.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 IQ PF00612.27 OEU05892.1 - 9.7e-17 59.1 19.5 0.002 17.8 0.3 7.6 7 0 0 7 7 7 7 IQ calmodulin-binding motif YL1 PF05764.13 OEU05892.1 - 0.0045 17.1 11.3 0.0045 17.1 11.3 4.4 3 1 0 3 3 3 1 YL1 nuclear protein Rbsn PF11464.8 OEU05892.1 - 1.7 8.4 17.8 33 4.3 0.2 5.7 5 0 0 5 5 5 0 Rabenosyn Rab binding domain Peptidase_C48 PF02902.19 OEU05893.1 - 2.1e-15 57.2 0.2 6.5e-15 55.5 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Bestrophin PF01062.21 OEU05894.1 - 2.7e-18 66.4 0.9 5.5e-18 65.4 0.9 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Usp PF00582.26 OEU05895.1 - 0.53 10.8 4.5 7.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Universal stress protein family Ytca PF17090.5 OEU05896.1 - 7.4 7.2 9.5 73 4.0 6.8 2.8 2 0 0 2 2 2 0 Uncharacterised protein family FGAR-AT_N PF18076.1 OEU05900.1 - 2.9e-14 53.0 0.0 4.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal DED PF01335.21 OEU05900.1 - 0.14 12.5 1.9 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 Death effector domain DUF1178 PF06676.11 OEU05902.1 - 0.16 12.3 0.5 0.46 10.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF4407 PF14362.6 OEU05902.1 - 4.8 6.5 5.9 7.8 5.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSF_DNA-bind PF00447.17 OEU05904.1 - 1.8e-18 66.9 0.1 1.9e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Sporozoite_P67 PF05642.11 OEU05906.1 - 0.009 14.2 0.8 0.011 13.8 0.8 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF3439 PF11921.8 OEU05906.1 - 0.16 11.9 2.9 0.25 11.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) E1_UFD PF09358.10 OEU05906.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold domain CENP-T_C PF15511.6 OEU05907.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU05907.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OEU05907.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OEU05907.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU05907.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OEU05907.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OEU05907.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OEU05907.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 OEU05908.1 - 3.5e-20 71.4 2.2 5.7e-20 70.8 2.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OEU05908.1 - 2.6e-11 44.0 0.0 3e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OEU05908.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRM_1 PF00076.22 OEU05909.1 - 9e-17 60.7 0.1 1.5e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2559 PF10832.8 OEU05909.1 - 0.048 13.7 0.6 0.086 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) RRM_7 PF16367.5 OEU05909.1 - 0.087 12.9 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif PAS_6 PF08348.11 OEU05914.1 - 0.0031 17.3 1.1 0.012 15.5 0.8 2.1 2 0 0 2 2 2 1 YheO-like PAS domain SelR PF01641.18 OEU05915.1 - 4.9e-10 39.5 0.0 6.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 SelR domain Ank_2 PF12796.7 OEU05917.1 - 1.4e-06 28.8 1.3 0.00028 21.4 0.0 3.4 1 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU05917.1 - 2.5e-06 27.4 0.2 0.0015 18.8 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OEU05917.1 - 3.4e-05 24.0 0.1 0.0062 16.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU05917.1 - 5.1e-05 23.7 0.1 0.027 15.0 0.0 3.8 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU05917.1 - 0.0032 17.8 0.0 0.098 13.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat VAR1 PF05316.12 OEU05917.1 - 0.02 13.9 0.2 0.02 13.9 0.2 1.7 2 1 0 2 2 2 0 Mitochondrial ribosomal protein (VAR1) Bd3614-deam PF14439.6 OEU05917.1 - 0.053 13.6 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase Mei5_like PF17021.5 OEU05918.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.0 1 1 1 2 2 2 0 Putative double-strand recombination repair-like E1_UFD PF09358.10 OEU05919.1 - 0.034 14.9 2.5 3.1 8.6 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin fold domain ABC2_membrane_3 PF12698.7 OEU05919.1 - 0.5 9.4 1.8 1.1 8.3 1.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein YHS PF04945.13 OEU05921.1 - 0.0056 16.8 0.0 7.7 6.7 0.0 3.0 2 0 0 2 2 2 2 YHS domain PerB PF06590.11 OEU05921.1 - 0.0099 16.4 0.1 9.9 6.7 0.0 2.6 2 0 0 2 2 2 2 PerB protein ApbA PF02558.16 OEU05921.1 - 0.021 14.5 1.0 7.6 6.2 0.1 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Big_11 PF18200.1 OEU05921.1 - 0.075 13.0 0.7 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain Dishevelled PF02377.15 OEU05921.1 - 0.18 12.2 6.4 7.2 7.0 0.6 2.7 2 0 0 2 2 2 0 Dishevelled specific domain Homeobox_KN PF05920.11 OEU05921.1 - 0.34 10.9 2.9 19 5.3 0.2 2.8 2 0 0 2 2 2 0 Homeobox KN domain Abhydrolase_5 PF12695.7 OEU05922.1 - 2e-08 34.2 0.6 0.00062 19.6 0.0 4.0 4 0 0 4 4 4 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OEU05922.1 - 0.0002 20.3 0.0 0.0005 19.1 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 OEU05922.1 - 0.00029 20.5 0.3 0.006 16.2 0.0 2.6 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 OEU05922.1 - 0.0011 19.2 0.0 2 8.5 0.0 3.2 2 1 0 3 3 3 2 Thioesterase domain Hydrolase_4 PF12146.8 OEU05922.1 - 0.0017 17.6 0.0 4.3 6.5 0.0 3.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OEU05922.1 - 0.007 15.4 0.1 0.024 13.6 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 OEU05922.1 - 0.13 10.7 0.0 0.13 10.7 0.0 2.7 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF2228 PF10228.9 OEU05922.1 - 0.16 11.7 3.2 3.6 7.3 3.5 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) Peroxin-13_N PF04088.13 OEU05922.1 - 0.36 11.1 3.8 0.36 11.1 0.8 2.4 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF4349 PF14257.6 OEU05923.1 - 0.04 13.4 1.4 0.071 12.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PRP1_N PF06424.12 OEU05923.1 - 1.3 9.4 10.3 2.3 8.6 10.3 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Macoilin PF09726.9 OEU05923.1 - 3.9 5.9 10.3 6.6 5.2 10.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF4661 PF15576.6 OEU05923.1 - 9.9 6.0 7.6 15 5.4 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PI-PLC-X PF00388.19 OEU05924.1 - 1.3e-26 92.9 0.0 2.7e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OEU05924.1 - 3.2e-19 69.4 0.1 5.7e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OEU05924.1 - 4.3e-10 39.8 0.0 2.3e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 C2 domain GDP_Man_Dehyd PF16363.5 OEU05926.1 - 9.2e-46 156.8 0.1 2.6e-45 155.3 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU05926.1 - 1.2e-34 119.9 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OEU05926.1 - 8.8e-06 25.1 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OEU05926.1 - 2.7e-05 23.5 0.2 0.0051 16.0 0.1 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU05926.1 - 0.00012 21.4 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Complex1_LYR PF05347.15 OEU05927.1 - 5.5e-10 39.2 0.2 1.1e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OEU05927.1 - 5.3e-05 23.9 0.2 0.00012 22.8 0.2 1.6 1 0 0 1 1 1 1 Complex1_LYR-like VASP_tetra PF08776.11 OEU05927.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain NOA36 PF06524.12 OEU05927.1 - 0.28 10.5 3.9 0.42 9.9 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.9 OEU05927.1 - 0.77 8.2 12.6 0.99 7.9 12.6 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OEU05927.1 - 3 6.5 5.3 3.1 6.5 5.3 1.2 1 0 0 1 1 1 0 Presenilin DUF2802 PF10975.8 OEU05928.1 - 7.5 6.8 11.4 13 6.0 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) YL1 PF05764.13 OEU05929.1 - 0.13 12.4 3.0 0.21 11.7 3.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Tic22 PF04278.12 OEU05930.1 - 3e-12 46.5 0.0 2.9e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Tic22-like family CAF1 PF04857.20 OEU05931.1 - 1.4e-16 60.6 0.6 2.2e-07 30.4 0.0 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease DUF1474 PF07342.11 OEU05931.1 - 0.024 15.2 0.0 0.084 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) RNase_H_2 PF13482.6 OEU05931.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily Thioredoxin PF00085.20 OEU05932.1 - 1e-21 76.8 0.2 2.1e-21 75.8 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin ERGIC_N PF13850.6 OEU05932.1 - 2.9e-18 66.0 0.8 9.6e-18 64.3 0.8 2.0 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 OEU05932.1 - 1e-12 48.4 0.5 2.6e-12 47.1 0.5 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter OST3_OST6 PF04756.13 OEU05932.1 - 0.0011 18.4 0.5 0.0022 17.4 0.1 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OEU05932.1 - 0.0072 16.6 0.0 0.029 14.7 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU05932.1 - 0.009 16.5 0.4 0.045 14.2 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain TPR_1 PF00515.28 OEU05933.1 - 7.4e-05 22.4 8.4 0.29 11.0 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU05933.1 - 0.0014 18.6 10.6 6.3 7.2 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU05933.1 - 0.0086 16.3 15.9 0.45 10.8 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU05933.1 - 0.92 9.9 8.2 7.5 7.0 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU05933.1 - 4.5 8.3 6.2 40 5.4 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat HA PF03457.14 OEU05934.1 - 1.4e-36 124.6 2.2 1.8e-20 73.0 0.4 2.0 2 0 0 2 2 2 2 Helicase associated domain Mhr1 PF12829.7 OEU05934.1 - 0.018 15.1 0.5 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination C_LFY_FLO PF17538.2 OEU05934.1 - 0.028 13.9 0.5 0.059 12.9 0.5 1.6 1 1 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula His_Phos_1 PF00300.22 OEU05935.1 - 1.4e-32 113.0 0.2 1.6e-18 67.1 0.0 3.0 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) SUIM_assoc PF16619.5 OEU05935.1 - 0.046 13.8 0.0 0.046 13.8 0.0 2.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DDE_Tnp_1_7 PF13843.6 OEU05936.1 - 2.9e-17 63.0 0.0 4.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 lci PF12197.8 OEU05937.1 - 0.017 14.9 79.3 0.12 12.2 1.1 10.9 5 1 6 11 11 11 0 Bacillus cereus group antimicrobial protein Rep_fac-A_3 PF08661.11 OEU05939.1 - 7.1e-06 26.3 0.0 2.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Replication factor A protein 3 FKS1_dom1 PF14288.6 OEU05939.1 - 0.07 13.5 0.4 0.11 12.9 0.4 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Hydrolase_4 PF12146.8 OEU05940.1 - 3.6e-13 49.3 0.1 2.8e-12 46.4 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU05940.1 - 1.2e-05 25.1 0.0 0.012 15.3 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 OEU05940.1 - 0.00014 21.4 0.4 0.049 13.0 0.1 2.4 2 0 0 2 2 2 2 Serine carboxypeptidase Abhydrolase_3 PF07859.13 OEU05940.1 - 0.00066 19.6 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU05940.1 - 0.0082 16.8 0.0 0.014 16.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 OEU05940.1 - 0.012 15.6 1.3 0.023 14.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 OEU05940.1 - 0.015 15.1 0.1 0.047 13.6 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Mntp PF02659.15 OEU05940.1 - 0.017 14.9 0.8 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 Putative manganese efflux pump Peptidase_S9 PF00326.21 OEU05940.1 - 0.04 13.4 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family SUIM_assoc PF16619.5 OEU05940.1 - 0.053 13.6 6.3 1.1 9.3 0.5 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DLH PF01738.18 OEU05940.1 - 0.063 12.8 0.4 1.2 8.6 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family HSF_DNA-bind PF00447.17 OEU05941.1 - 1.4e-10 41.6 0.4 1.8e-10 41.3 0.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1647 PF07801.11 OEU05941.1 - 0.047 13.4 1.2 0.066 13.0 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) DUF2262 PF10020.9 OEU05941.1 - 0.072 13.5 0.2 0.082 13.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) PTR2 PF00854.21 OEU05942.1 - 1.5e-11 43.8 19.1 2.2e-07 30.1 7.4 2.2 1 1 0 2 2 2 2 POT family APG9 PF04109.16 OEU05942.1 - 0.0043 16.1 0.2 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 Autophagy protein Apg9 Ank_2 PF12796.7 OEU05943.1 - 0.14 12.8 0.1 33 5.2 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) HA PF03457.14 OEU05944.1 - 1.9e-35 121.0 3.2 4e-17 62.3 0.3 2.0 2 0 0 2 2 2 2 Helicase associated domain CoaE PF01121.20 OEU05945.1 - 1.5e-24 86.7 2.8 2.1e-21 76.4 2.8 2.8 1 1 0 1 1 1 1 Dephospho-CoA kinase LMBR1 PF04791.16 OEU05945.1 - 0.0055 15.7 0.1 0.0067 15.4 0.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Dynamin_N PF00350.23 OEU05945.1 - 0.021 14.9 0.2 0.034 14.2 0.2 1.3 1 0 0 1 1 1 0 Dynamin family GCP_C_terminal PF04130.13 OEU05946.1 - 0.14 11.6 1.4 6.6 6.1 0.0 2.2 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal RasGAP PF00616.19 OEU05947.1 - 0.011 15.5 0.4 0.011 15.5 0.4 1.8 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Gemini_AL2 PF01440.16 OEU05947.1 - 4.2 7.8 9.5 0.78 10.2 4.0 2.3 1 1 1 2 2 2 0 Geminivirus AL2 protein Pex14_N PF04695.13 OEU05950.1 - 0.018 15.7 0.2 0.018 15.7 0.2 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRC2_HTH_1 PF18118.1 OEU05950.1 - 0.06 14.1 0.8 0.12 13.2 0.8 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Bul1_N PF04425.12 OEU05950.1 - 0.24 10.1 6.0 0.36 9.5 6.0 1.2 1 0 0 1 1 1 0 Bul1 N terminus DUF3446 PF11928.8 OEU05950.1 - 0.53 10.6 16.2 0.095 13.0 8.8 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Coilin_N PF15862.5 OEU05950.1 - 4.5 7.1 8.0 8.8 6.1 8.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus SR-25 PF10500.9 OEU05950.1 - 6 6.4 19.9 0.069 12.8 12.2 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RGP PF03214.13 OEU05952.1 - 0.039 13.1 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Gp_dh_C PF02800.20 OEU05954.1 - 6.9e-66 220.7 0.0 1.1e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU05954.1 - 7.7e-29 100.0 0.0 1.6e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Alpha_kinase PF02816.18 OEU05955.1 - 1.9e-24 86.8 0.1 2.2e-24 86.6 0.1 1.0 1 0 0 1 1 1 1 Alpha-kinase family sCache_2 PF17200.4 OEU05955.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Single Cache domain 2 LRR_6 PF13516.6 OEU05956.1 - 5.9e-09 35.3 23.7 0.017 15.1 0.1 7.1 7 0 0 7 7 7 4 Leucine Rich repeat CHAT PF12770.7 OEU05956.1 - 2.6e-05 23.8 0.0 5.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 CHAT domain LRR_8 PF13855.6 OEU05956.1 - 4.8e-05 23.0 17.4 0.04 13.7 0.1 6.1 3 1 2 5 5 5 3 Leucine rich repeat Macro PF01661.21 OEU05956.1 - 0.0058 16.7 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 Macro domain AAA_16 PF13191.6 OEU05956.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 OEU05956.1 - 0.079 12.1 0.0 0.23 10.6 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain LRR_4 PF12799.7 OEU05956.1 - 0.13 12.7 14.6 1 9.9 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU05956.1 - 0.53 11.0 14.6 12 7.0 0.7 6.1 5 0 0 5 5 5 0 Leucine Rich Repeat HMMR_N PF15905.5 OEU05958.1 - 0.0035 16.9 3.1 0.0041 16.6 2.5 1.3 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 OEU05958.1 - 0.0088 15.9 4.0 0.8 9.6 0.1 3.3 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3450 PF11932.8 OEU05958.1 - 0.032 13.5 2.7 0.084 12.2 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF722 PF05263.11 OEU05958.1 - 0.092 13.0 2.0 6.3 7.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF722) AAA_13 PF13166.6 OEU05958.1 - 0.8 8.3 5.2 0.72 8.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain PT PF04886.12 OEU05959.1 - 2e-13 49.6 61.8 9.9e-05 21.8 10.8 4.2 1 1 2 3 3 3 2 PT repeat MSSP PF03940.13 OEU05959.1 - 1.8 8.2 10.9 1.6e+03 -1.2 10.9 3.2 1 1 0 1 1 1 0 Male specific sperm protein PT PF04886.12 OEU05960.1 - 8e-11 41.3 47.0 0.00014 21.3 11.2 3.8 1 1 3 4 4 4 4 PT repeat PT PF04886.12 OEU05961.1 - 2.1e-09 36.7 56.6 1.8e+04 -25.1 56.6 5.1 1 1 0 1 1 1 0 PT repeat DUF285 PF03382.14 OEU05962.1 - 8.7e-73 241.8 35.9 7.3e-40 135.5 15.7 2.3 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Phage_tail_2 PF06199.11 OEU05962.1 - 0.0034 17.5 4.9 1.1 9.3 0.2 3.2 1 1 1 3 3 3 2 Phage tail tube protein Fimbrial_K88 PF02432.15 OEU05962.1 - 0.014 15.3 3.0 5.2 7.0 0.1 3.9 1 1 4 5 5 5 0 Fimbrial, major and minor subunit Acyl-CoA_ox_N PF14749.6 OEU05962.1 - 0.028 15.0 0.0 26 5.4 0.0 3.0 1 1 2 3 3 3 0 Acyl-coenzyme A oxidase N-terminal Cir_N PF10197.9 OEU05962.1 - 1.1 9.5 4.3 1.2e+02 3.0 0.3 3.7 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR SEP PF08059.13 OEU05963.1 - 5.1e-21 75.0 0.0 7.5e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OEU05963.1 - 0.023 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 UBX domain RRM_1 PF00076.22 OEU05965.1 - 1.7e-05 24.6 0.0 9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 OEU05965.1 - 0.00014 21.8 1.9 0.0085 16.1 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU05965.1 - 0.00049 20.3 0.1 0.0029 17.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU05965.1 - 0.0017 18.1 3.0 0.0095 15.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU05965.1 - 0.063 13.4 0.0 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU05965.1 - 0.096 13.0 3.3 0.75 10.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2538 PF10804.8 OEU05965.1 - 0.13 12.0 1.3 0.39 10.5 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) TPR_6 PF13174.6 OEU05965.1 - 0.19 12.5 0.8 2.7 8.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Connexin PF00029.19 OEU05966.1 - 0.0016 18.2 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 Connexin E7 PF00527.18 OEU05966.1 - 0.005 17.0 2.2 0.01 16.0 2.2 1.5 1 0 0 1 1 1 1 E7 protein, Early protein Orf78 PF06024.12 OEU05966.1 - 0.01 16.1 5.1 0.048 14.0 5.1 2.1 1 1 0 1 1 1 0 Orf78 (ac78) MFMR_assoc PF16596.5 OEU05966.1 - 0.012 16.1 0.1 0.012 16.1 0.1 1.4 2 0 0 2 2 2 0 Disordered region downstream of MFMR FemAB PF02388.16 OEU05966.1 - 0.013 14.4 0.9 0.018 14.0 0.9 1.1 1 0 0 1 1 1 0 FemAB family Goodbye PF17109.5 OEU05966.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain PBP1_TM PF14812.6 OEU05966.1 - 0.084 13.2 3.9 0.19 12.1 3.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal V_ATPase_I PF01496.19 OEU05966.1 - 0.2 9.5 3.0 0.27 9.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 OEU05966.1 - 0.56 8.9 2.3 0.6 8.8 2.3 1.3 1 0 0 1 1 1 0 Presenilin DUF5349 PF17298.2 OEU05966.1 - 8.9 6.0 10.9 0.58 9.9 6.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5349) ArfGap PF01412.18 OEU05967.1 - 9.3e-32 109.6 0.0 1.1e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 OEU05967.1 - 0.017 15.0 1.4 0.16 11.9 0.1 2.4 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger VSP PF03302.13 OEU05967.1 - 0.11 11.4 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Phage_connector PF05352.12 OEU05968.1 - 0.0083 15.6 1.8 0.014 14.8 1.8 1.3 1 0 0 1 1 1 1 Phage Connector (GP10) DUF501 PF04417.12 OEU05968.1 - 0.086 12.6 6.7 0.067 13.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF501) TFIIA PF03153.13 OEU05968.1 - 0.28 11.1 17.3 0.35 10.8 17.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sacchrp_dh_C PF16653.5 OEU05968.1 - 1.7 8.7 6.0 0.42 10.7 2.4 1.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain DDE_Tnp_1_7 PF13843.6 OEU05969.1 - 1e-22 80.9 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 zf-B_box PF00643.24 OEU05969.1 - 0.0034 17.5 5.1 0.0095 16.1 5.1 1.7 1 0 0 1 1 1 1 B-box zinc finger PHD_2 PF13831.6 OEU05969.1 - 0.15 11.7 3.2 0.45 10.1 3.2 1.8 1 0 0 1 1 1 0 PHD-finger IBR PF01485.21 OEU05969.1 - 3.1 8.1 8.0 0.64 10.3 3.4 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain HMG_box PF00505.19 OEU05971.1 - 1.5e-08 34.9 1.6 1.6e-08 34.8 1.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU05971.1 - 2.5e-05 24.8 1.5 2.7e-05 24.7 1.5 1.1 1 0 0 1 1 1 1 HMG-box domain DUF3742 PF12553.8 OEU05971.1 - 0.15 12.2 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) TMEM171 PF15471.6 OEU05972.1 - 0.0048 15.9 2.3 0.0048 15.9 2.3 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 HMG_box PF00505.19 OEU05972.1 - 0.007 16.8 0.2 0.007 16.8 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box YABBY PF04690.13 OEU05972.1 - 0.06 13.9 1.7 0.066 13.8 1.7 1.0 1 0 0 1 1 1 0 YABBY protein RCDG1 PF15725.5 OEU05972.1 - 0.092 13.2 1.8 0.1 13.0 1.8 1.1 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Yae1_N PF09811.9 OEU05973.1 - 4.5e-08 32.7 52.9 0.58 9.9 0.7 12.0 4 2 7 11 11 11 7 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU05973.1 - 0.0014 18.6 37.7 17 5.5 6.8 6.8 1 1 2 3 3 3 1 Glycine zipper Rick_17kDa_Anti PF05433.15 OEU05973.1 - 0.008 16.0 1.1 0.008 16.0 1.1 7.5 3 2 5 8 8 8 4 Glycine zipper 2TM domain OpcA PF07239.11 OEU05973.1 - 0.11 12.1 1.9 55 3.3 0.0 4.2 2 2 2 5 5 5 0 Outer membrane protein OpcA Gly-zipper_OmpA PF13436.6 OEU05973.1 - 0.2 11.5 31.8 1.5 8.6 1.3 7.0 2 2 3 5 5 5 0 Glycine-zipper domain DUF1290 PF06947.12 OEU05973.1 - 2.1 8.5 8.5 31 4.7 0.3 5.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1290) MccV PF17508.2 OEU05973.1 - 2.5 8.7 6.3 60 4.3 0.3 4.1 1 1 3 5 5 5 0 Microcin V bacteriocin DUF2052 PF09747.9 OEU05975.1 - 0.0036 17.5 6.1 0.0036 17.5 6.1 2.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) PGPGW PF09656.10 OEU05975.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Coiled-coil_56 PF09813.9 OEU05975.1 - 0.039 14.0 0.3 0.13 12.3 0.3 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 NSP2-B_epitope PF14757.6 OEU05975.1 - 6.4 6.4 10.4 1.3 8.7 5.5 2.1 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Myb_DNA-binding PF00249.31 OEU05976.1 - 5.9e-32 109.6 11.0 4.8e-18 65.1 0.9 2.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU05976.1 - 2.7e-27 94.8 8.7 7.7e-19 67.7 0.4 2.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU05976.1 - 1.2e-06 28.3 0.1 0.011 15.6 0.1 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OEU05976.1 - 0.0055 16.7 0.0 2.7 8.1 0.0 2.2 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OEU05976.1 - 0.0061 16.7 0.3 0.2 11.9 0.0 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 DUF3494 PF11999.8 OEU05977.1 - 6.6e-57 192.5 15.4 7.8e-57 192.3 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) LRR_adjacent PF08191.11 OEU05977.1 - 0.076 13.2 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 LRR adjacent BCHF PF07284.11 OEU05977.1 - 0.11 12.6 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF3494 PF11999.8 OEU05978.1 - 7.4e-45 153.1 12.4 1e-44 152.7 12.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Bactofilin PF04519.13 OEU05978.1 - 0.025 14.9 0.2 0.11 12.8 0.1 2.1 2 0 0 2 2 2 0 Polymer-forming cytoskeletal SNF2_N PF00176.23 OEU05979.1 - 9.4e-46 156.1 0.0 4.8e-44 150.5 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 OEU05979.1 - 3.1e-10 39.8 5.0 5.1e-05 23.1 0.4 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OEU05979.1 - 0.0023 17.9 0.0 0.0023 17.9 0.0 4.0 4 1 0 4 4 4 2 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU05979.1 - 0.0057 16.4 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3295 PF11702.8 OEU05980.1 - 0.018 14.4 1.8 0.028 13.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) NPF PF16601.5 OEU05981.1 - 1.6 9.2 14.4 1.4 9.4 8.1 2.4 1 1 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif RasGAP_C PF03836.15 OEU05982.1 - 0.0037 17.4 1.7 0.0037 17.4 1.7 2.0 1 1 1 2 2 2 1 RasGAP C-terminus COG5 PF10392.9 OEU05982.1 - 0.018 15.2 1.0 2.2 8.5 0.4 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Cnl2_NKP2 PF09447.10 OEU05982.1 - 0.033 14.4 1.3 1.7 8.8 0.4 2.4 1 1 1 2 2 2 0 Cnl2/NKP2 family protein Mei5_like PF17021.5 OEU05982.1 - 0.034 14.2 0.1 0.034 14.2 0.1 2.2 1 1 1 2 2 2 0 Putative double-strand recombination repair-like DUF4419 PF14388.6 OEU05982.1 - 0.045 13.2 0.2 0.067 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) ACD PF16671.5 OEU05982.1 - 0.073 11.4 0.5 0.098 11.0 0.5 1.1 1 0 0 1 1 1 0 Actin cross-linking domain GT-D PF08759.11 OEU05982.1 - 0.083 12.6 1.4 0.15 11.7 1.4 1.5 1 1 0 1 1 1 0 Glycosyltransferase GT-D fold DUF4407 PF14362.6 OEU05983.1 - 0.0062 15.9 1.4 0.0073 15.7 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF3037 PF11236.8 OEU05983.1 - 0.032 14.6 0.4 0.048 14.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Mei5_like PF17021.5 OEU05983.1 - 0.053 13.6 0.2 0.053 13.6 0.2 2.4 1 1 1 2 2 2 0 Putative double-strand recombination repair-like PIN_8 PF18476.1 OEU05983.1 - 0.072 12.9 5.5 0.084 12.7 5.5 1.1 1 0 0 1 1 1 0 PIN like domain PIN_12 PF16289.5 OEU05983.1 - 0.087 13.3 4.3 0.11 13.0 4.3 1.1 1 0 0 1 1 1 0 PIN domain zf-CHC2 PF01807.20 OEU05985.1 - 2.4e-18 65.7 0.2 5.3e-17 61.4 0.2 2.0 1 1 0 1 1 1 1 CHC2 zinc finger LTP_2 PF14368.6 OEU05985.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Probable lipid transfer HTH_34 PF13601.6 OEU05988.1 - 0.083 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain RRM_1 PF00076.22 OEU05993.1 - 5.1e-26 90.3 1.9 1.5e-13 50.3 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU05993.1 - 2.9e-07 30.5 0.5 2.5e-06 27.5 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OEU05993.1 - 0.0021 18.0 0.2 0.88 9.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 OEU05993.1 - 0.067 13.0 0.0 3.4 7.4 0.0 2.3 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Phytochelatin PF05023.14 OEU05993.1 - 0.077 12.2 0.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Phytochelatin synthase DUF4651 PF15513.6 OEU05993.1 - 0.12 12.2 0.2 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) PhetRS_B1 PF18262.1 OEU05993.1 - 0.16 12.2 0.0 4.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Sugar_tr PF00083.24 OEU05995.1 - 7.9e-21 74.4 15.7 3.8e-10 39.2 9.0 3.4 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OEU05995.1 - 1.1e-16 60.8 14.5 1.8e-06 27.2 2.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF599 PF04654.12 OEU05995.1 - 0.0017 17.8 0.8 0.038 13.4 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF599 CENP-B_dimeris PF09026.10 OEU05995.1 - 0.022 15.1 0.5 0.022 15.1 0.5 3.8 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Peptidase_M56 PF05569.11 OEU05995.1 - 0.04 13.1 0.0 0.13 11.4 0.0 1.8 1 0 0 1 1 1 0 BlaR1 peptidase M56 DHHC PF01529.20 OEU05995.1 - 0.076 13.1 0.0 0.076 13.1 0.0 5.1 2 2 3 6 6 5 0 DHHC palmitoyltransferase ETRAMP PF09716.10 OEU05995.1 - 0.14 12.2 9.5 9.6 6.4 0.1 5.1 5 0 0 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) Cwf_Cwc_15 PF04889.12 OEU05995.1 - 0.69 9.6 12.3 1.4 8.6 3.3 3.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Conotoxin PF02950.17 OEU05995.1 - 0.8 10.8 4.3 49 5.0 0.1 4.0 4 0 0 4 4 3 0 Conotoxin FAM176 PF14851.6 OEU05995.1 - 1.4 8.6 6.5 3.7 7.2 1.2 3.7 3 1 0 3 3 3 0 FAM176 family DUF2407_C PF13373.6 OEU05995.1 - 3.9 7.7 7.7 9.4 6.4 0.0 3.9 3 1 1 4 4 4 0 DUF2407 C-terminal domain Baculo_11_kDa PF06143.11 OEU05995.1 - 5.4 6.7 9.7 0.23 11.0 0.3 3.3 4 0 0 4 4 4 0 Baculovirus 11 kDa family DUF2722 PF10846.8 OEU05995.1 - 5.6 5.8 15.9 0.77 8.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RVT_2 PF07727.14 OEU05996.1 - 0.0059 16.3 0.0 0.0064 16.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peripla_BP_2 PF01497.18 OEU05997.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Mucin PF01456.17 OEU05998.1 - 0.0088 16.0 14.8 0.012 15.6 14.8 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein FSA_C PF10479.9 OEU05998.1 - 2.1 6.4 8.0 2.4 6.2 8.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF285 PF03382.14 OEU05999.1 - 1.8e-60 202.0 30.1 1e-34 118.9 12.6 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF1329 PF07044.11 OEU05999.1 - 0.015 14.6 0.4 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) DUF1266 PF06889.11 OEU05999.1 - 0.016 15.3 0.2 0.17 11.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1266) PT PF04886.12 OEU06000.1 - 3.9e-09 35.9 58.3 1 9.0 13.3 4.6 1 1 1 2 2 2 1 PT repeat Herpes_gE PF02480.16 OEU06001.1 - 0.11 11.2 0.7 0.17 10.6 0.7 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RsfS PF02410.15 OEU06002.1 - 1.4e-10 41.4 0.0 1e-09 38.7 0.0 2.4 2 1 0 2 2 2 1 Ribosomal silencing factor during starvation DUF4843 PF16132.5 OEU06002.1 - 0.41 10.2 1.8 0.42 10.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Dirigent PF03018.14 OEU06004.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 Dirigent-like protein Sulfotransfer_3 PF13469.6 OEU06005.1 - 0.022 15.2 0.2 0.05 14.0 0.2 1.7 1 0 0 1 1 1 0 Sulfotransferase family HDC PF02329.16 OEU06005.1 - 0.034 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain Stealth_CR4 PF17103.5 OEU06005.1 - 0.052 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Mucin PF01456.17 OEU06005.1 - 6.4 6.8 13.4 7.4 6.6 2.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Sulfotransfer_2 PF03567.14 OEU06006.1 - 1.2e-06 28.6 1.6 0.00056 19.9 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family DUF1053 PF06327.14 OEU06006.1 - 3.6 8.2 6.6 0.89 10.2 2.0 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) DNA_pol_B_N PF18094.1 OEU06007.1 - 0.027 15.0 1.5 0.031 14.8 1.5 1.3 1 1 0 1 1 1 0 DNA polymerase beta N-terminal domain Peroxin-13_N PF04088.13 OEU06007.1 - 0.05 13.9 0.1 0.22 11.8 0.1 1.8 1 1 1 2 2 2 0 Peroxin 13, N-terminal region O-ag_pol_Wzy PF14296.6 OEU06007.1 - 0.057 12.1 0.3 0.068 11.8 0.3 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF872 PF05915.12 OEU06007.1 - 0.1 12.8 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Orf78 PF06024.12 OEU06007.1 - 0.13 12.5 2.8 0.35 11.2 0.6 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Porph_ging PF09697.10 OEU06007.1 - 0.34 11.5 2.4 0.83 10.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) ABC_tran PF00005.27 OEU06008.1 - 1.8e-19 70.6 0.1 2.5e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU06008.1 - 0.012 15.4 1.0 2.2 8.0 0.2 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Csc2 PF18320.1 OEU06008.1 - 0.027 13.4 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Csc2 Crispr SMC_N PF02463.19 OEU06008.1 - 0.08 12.4 0.5 0.3 10.5 0.5 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 OEU06008.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Amino_oxidase PF01593.24 OEU06010.1 - 2e-06 27.4 0.0 3.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase BRF1 PF07741.13 OEU06011.1 - 0.017 15.5 1.1 0.017 15.5 1.1 4.0 4 1 0 4 4 4 0 Brf1-like TBP-binding domain Mis12 PF05859.12 OEU06011.1 - 0.037 14.1 7.5 0.31 11.1 7.5 2.6 1 1 0 1 1 1 0 Mis12 protein Fungal_TACC PF12709.7 OEU06011.1 - 0.052 14.0 1.6 0.052 14.0 1.6 3.4 5 0 0 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins KCT2 PF17818.1 OEU06013.1 - 9.1 6.4 12.3 1.5 8.9 4.0 2.2 1 1 0 2 2 2 0 Keratinocyte-associated gene product Fea1 PF07692.11 OEU06014.1 - 2.7e-05 23.4 0.1 2.8e-05 23.4 0.1 1.0 1 0 0 1 1 1 1 Low iron-inducible periplasmic protein DUF2208 PF09973.9 OEU06015.1 - 0.68 9.5 4.3 0.32 10.6 0.3 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF3149 PF11346.8 OEU06015.1 - 4.8 6.9 8.0 12 5.6 1.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) zf-MYND PF01753.18 OEU06016.1 - 1.3e-08 34.8 14.4 2.4e-08 33.9 14.4 1.4 1 0 0 1 1 1 1 MYND finger Sel1 PF08238.12 OEU06016.1 - 0.011 16.4 0.0 0.11 13.3 0.0 2.5 3 0 0 3 3 3 0 Sel1 repeat NDC10_II PF16787.5 OEU06016.1 - 0.14 11.2 0.4 0.2 10.7 0.4 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF4385 PF14328.6 OEU06017.1 - 0.3 11.1 6.5 7.9 6.5 6.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4385) Secretin_N_2 PF07655.13 OEU06017.1 - 2.6 8.6 31.3 1.5 9.4 11.4 3.7 3 0 0 3 3 3 0 Secretin N-terminal domain DUF3664 PF12406.8 OEU06021.1 - 0.4 11.3 6.0 0.089 13.4 2.0 1.8 1 1 0 2 2 2 0 Surface protein ILVD_EDD PF00920.21 OEU06022.1 - 1.1e-202 674.3 0.0 1.3e-202 674.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family ClpS PF02617.17 OEU06024.1 - 1.1e-14 54.0 0.0 2.2e-14 53.0 0.0 1.5 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS TMEM154 PF15102.6 OEU06028.1 - 3.7e-05 23.7 0.0 3.7e-05 23.7 0.0 3.6 3 0 0 3 3 3 1 TMEM154 protein family LST1 PF05083.13 OEU06028.1 - 0.024 14.9 1.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 0 LST-1 protein LSR PF05624.14 OEU06028.1 - 0.075 13.0 5.0 0.14 12.1 5.0 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) EphA2_TM PF14575.6 OEU06028.1 - 0.11 13.4 7.6 0.3 12.0 3.2 3.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 OEU06028.1 - 0.13 11.0 0.0 0.13 11.0 0.0 2.6 3 1 1 4 4 4 0 Alphaherpesvirus glycoprotein E Shisa PF13908.6 OEU06028.1 - 1.7 8.9 8.5 0.44 10.7 1.3 3.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Tmemb_9 PF05434.11 OEU06028.1 - 3.6 7.5 0.0 3.6 7.5 0.0 2.9 3 0 0 3 3 3 0 TMEM9 Nop14 PF04147.12 OEU06028.1 - 7.5 4.6 18.6 13 3.8 18.6 1.4 1 0 0 1 1 1 0 Nop14-like family LAGLIDADG_2 PF03161.13 OEU06029.1 - 0.039 14.0 0.2 11 6.0 0.1 2.3 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family PAP2 PF01569.21 OEU06030.1 - 1.1e-19 70.6 0.1 2e-19 69.7 0.1 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OEU06030.1 - 1.2e-05 25.1 0.2 0.08 12.6 0.5 2.1 2 0 0 2 2 2 2 PAP2 superfamily 7tm_1 PF00001.21 OEU06030.1 - 0.0031 16.9 0.0 0.0037 16.6 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5349 PF17298.2 OEU06030.1 - 0.01 15.6 11.6 0.013 15.3 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Orf78 PF06024.12 OEU06030.1 - 0.012 15.9 1.5 0.012 15.9 1.5 1.9 1 1 1 2 2 2 0 Orf78 (ac78) PAP2_C PF14360.6 OEU06030.1 - 0.016 15.7 3.1 0.86 10.2 0.3 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF4834 PF16118.5 OEU06030.1 - 0.028 15.4 0.3 0.028 15.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Menin PF05053.13 OEU06030.1 - 0.62 8.3 3.2 0.69 8.2 3.2 1.2 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 OEU06030.1 - 6.9 7.3 15.7 0.14 12.7 6.5 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain LRR_4 PF12799.7 OEU06031.1 - 9.4e-12 45.0 14.2 0.0058 17.0 0.9 4.8 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU06031.1 - 3.7e-06 26.6 9.5 0.0071 16.1 0.3 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OEU06031.1 - 0.002 18.0 0.8 16 5.9 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich repeat DUF2373 PF10180.9 OEU06031.1 - 0.45 10.4 1.4 34 4.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) LRR_1 PF00560.33 OEU06031.1 - 5.4 8.0 7.3 1.4e+02 3.6 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat TIP41 PF04176.13 OEU06032.1 - 1.4e-24 86.5 0.1 1.5e-24 86.4 0.1 1.0 1 0 0 1 1 1 1 TIP41-like family zf-RVT PF13966.6 OEU06033.1 - 0.025 15.3 1.6 0.082 13.6 1.6 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Mei5_like PF17021.5 OEU06033.1 - 0.07 13.2 3.3 0.14 12.2 0.1 3.1 2 1 1 3 3 3 0 Putative double-strand recombination repair-like Ferritin PF00210.24 OEU06036.1 - 0.04 13.8 0.2 0.04 13.8 0.2 1.9 2 0 0 2 2 2 0 Ferritin-like domain Phasin_2 PF09361.10 OEU06037.1 - 0.0024 18.1 9.4 0.0037 17.5 9.4 1.3 1 0 0 1 1 1 1 Phasin protein ATP-synt_B PF00430.18 OEU06037.1 - 0.0039 17.3 9.8 0.0054 16.8 9.8 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Perilipin PF03036.16 OEU06037.1 - 0.0045 16.1 10.7 0.01 14.9 10.6 1.6 1 1 1 2 2 2 1 Perilipin family Mitofilin PF09731.9 OEU06037.1 - 0.01 14.7 8.1 0.012 14.5 8.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 OEU06037.1 - 0.015 15.9 11.9 0.055 14.1 11.9 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 OEU06037.1 - 0.12 12.9 13.5 19 5.9 13.5 2.4 1 1 0 1 1 1 0 YtxH-like protein SpoIIIAH PF12685.7 OEU06037.1 - 0.12 12.1 15.1 0.15 11.8 15.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein HisKA_3 PF07730.13 OEU06037.1 - 0.37 11.3 5.7 1e+02 3.5 5.7 2.9 1 1 0 1 1 1 0 Histidine kinase DUF3292 PF11696.8 OEU06037.1 - 3.1 6.1 10.4 3.9 5.7 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Chlorosome_CsmC PF11098.8 OEU06037.1 - 5.5 7.0 24.0 2.2 8.2 15.9 2.2 1 1 1 2 2 2 0 Chlorosome envelope protein C ISG65-75 PF11727.8 OEU06037.1 - 5.8 6.1 17.9 7.1 5.8 12.0 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1542 PF07564.11 OEU06037.1 - 8 6.7 22.6 8.1 6.6 20.8 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) BTB PF00651.31 OEU06039.1 - 0.00042 20.5 0.3 0.00075 19.7 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain Pilosulin PF17499.2 OEU06040.1 - 1.4 9.1 8.7 4.3e+02 1.2 8.5 3.4 1 1 0 1 1 1 0 Ant venom peptides PT PF04886.12 OEU06041.1 - 1.9e-05 24.1 55.6 0.001 18.5 22.4 3.0 2 0 0 2 2 2 2 PT repeat Sugar_tr PF00083.24 OEU06042.1 - 8.5e-08 31.5 1.5 8.7e-08 31.5 1.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter UPF0225 PF17775.1 OEU06044.1 - 1.8e-12 47.9 2.3 7.9e-12 45.9 2.3 2.0 1 1 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 OEU06044.1 - 1.7 8.7 6.9 2.1 8.3 2.1 2.3 2 0 0 2 2 2 0 SEC-C motif BTB_2 PF02214.22 OEU06045.1 - 7.7e-14 51.8 0.0 1.5e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain DUF3402 PF11882.8 OEU06046.1 - 0.00083 18.6 7.8 0.0011 18.2 7.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) Viral_helicase1 PF01443.18 OEU06046.1 - 0.0018 18.0 1.6 0.0023 17.7 1.6 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase LRRC37AB_C PF14914.6 OEU06046.1 - 0.0036 17.2 1.1 0.0036 17.2 1.1 2.2 2 0 0 2 2 2 1 LRRC37A/B like protein 1 C-terminal domain EphA2_TM PF14575.6 OEU06046.1 - 0.017 16.0 0.1 0.052 14.4 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Internalin_N PF12354.8 OEU06046.1 - 0.026 14.6 0.6 0.043 13.9 0.6 1.4 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal SID-1_RNA_chan PF13965.6 OEU06046.1 - 0.028 12.8 5.4 0.035 12.5 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MSC PF09402.10 OEU06046.1 - 0.039 13.4 0.3 0.061 12.8 0.0 1.4 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF4574 PF15141.6 OEU06046.1 - 0.054 13.4 0.1 0.43 10.5 0.0 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF3139 PF11337.8 OEU06046.1 - 0.081 13.6 0.4 0.081 13.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Ctr PF04145.15 OEU06046.1 - 0.14 12.8 1.1 1.5 9.4 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Peptidase_S49_N PF08496.10 OEU06046.1 - 0.15 12.1 1.5 0.23 11.5 0.0 1.8 1 1 1 2 2 2 0 Peptidase family S49 N-terminal O-antigen_lig PF13425.6 OEU06046.1 - 0.23 10.2 8.3 0.051 12.4 5.1 1.5 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Shisa PF13908.6 OEU06046.1 - 0.28 11.4 7.5 0.59 10.3 7.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Serinc PF03348.15 OEU06046.1 - 0.35 9.7 3.7 0.44 9.4 3.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pilin_N PF07790.11 OEU06046.1 - 0.79 10.7 8.7 0.41 11.6 4.4 2.6 2 1 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Otopetrin PF03189.13 OEU06046.1 - 1.6 7.4 6.6 0.46 9.3 0.0 2.0 2 0 0 2 2 2 0 Otopetrin Sigma_reg_N PF13800.6 OEU06046.1 - 2.2 8.6 5.8 0.71 10.2 2.3 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CSG2 PF16965.5 OEU06046.1 - 2.9 6.7 8.3 0.28 10.1 0.2 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 OEU06046.1 - 3.9 6.2 10.4 0.041 12.7 0.4 1.9 1 1 0 2 2 2 0 HCO3- transporter family OAD_gamma PF04277.13 OEU06046.1 - 5 7.8 5.5 36 5.0 5.5 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Orf78 PF06024.12 OEU06046.1 - 6.9 7.0 22.1 0.21 11.9 6.6 2.7 1 1 0 2 2 2 0 Orf78 (ac78) CLN3 PF02487.17 OEU06046.1 - 7.1 5.6 5.4 1.1 8.2 0.6 1.7 1 1 1 2 2 2 0 CLN3 protein V_ATPase_I PF01496.19 OEU06046.1 - 8.2 4.2 8.8 0.21 9.5 1.3 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prenyltransf PF01255.19 OEU06047.1 - 5.5e-36 124.2 0.0 6e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DHHA2 PF02833.14 OEU06048.1 - 2e-21 76.7 0.2 3.7e-21 75.8 0.2 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 OEU06048.1 - 4.8e-11 42.8 0.4 1.3e-10 41.4 0.4 1.6 1 0 0 1 1 1 1 DHH family DUF4099 PF13351.6 OEU06048.1 - 0.093 13.0 0.1 1 9.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4099) CelTOS PF18659.1 OEU06048.1 - 0.22 12.0 2.1 2 8.9 0.3 2.7 2 1 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites YjeF_N PF03853.15 OEU06050.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Thioredoxin PF00085.20 OEU06051.1 - 2e-23 82.3 0.1 2.7e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OEU06051.1 - 1.8e-10 40.7 0.0 2.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OEU06051.1 - 5.4e-10 39.1 0.8 6.6e-10 38.8 0.8 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OEU06051.1 - 7.5e-08 32.8 0.2 1.2e-06 28.9 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU06051.1 - 1.6e-05 25.1 0.9 0.0031 17.8 0.0 2.8 1 1 2 3 3 3 1 Thioredoxin-like Glutaredoxin PF00462.24 OEU06051.1 - 0.00024 21.3 0.0 0.00092 19.4 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin DSBA PF01323.20 OEU06051.1 - 0.0014 18.5 0.1 0.88 9.3 0.1 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.6 OEU06051.1 - 0.0015 18.4 0.1 0.0026 17.6 0.1 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein DUF929 PF06053.11 OEU06051.1 - 0.0022 17.3 0.1 0.0028 17.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF929) DUF1947 PF09183.10 OEU06051.1 - 0.0041 17.4 0.3 0.014 15.7 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1947) Thioredoxin_7 PF13899.6 OEU06051.1 - 0.0054 16.9 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_5 PF13743.6 OEU06051.1 - 0.013 15.2 0.0 0.013 15.2 0.0 2.1 2 1 1 3 3 3 0 Thioredoxin YycH PF07435.11 OEU06051.1 - 0.016 14.2 0.8 0.021 13.8 0.8 1.1 1 0 0 1 1 1 0 YycH protein DUF836 PF05768.14 OEU06051.1 - 0.018 15.4 0.3 0.12 12.8 0.0 2.0 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.21 OEU06051.1 - 0.028 14.3 0.3 0.074 13.0 0.1 1.8 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 OEU06051.1 - 0.13 12.0 0.3 0.23 11.2 0.3 1.6 1 1 0 1 1 1 0 Redoxin CCDC53 PF10152.9 OEU06052.1 - 1.1e-40 139.5 86.0 4.8e-10 40.1 0.2 10.4 10 1 0 10 10 10 7 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 OEU06052.1 - 0.0037 17.3 4.7 0.0037 17.3 4.7 4.5 3 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2076) UBA_2 PF08587.11 OEU06052.1 - 0.08 13.1 8.2 45 4.3 0.2 5.3 5 0 0 5 5 5 0 Ubiquitin associated domain (UBA) MCRS_N PF13325.6 OEU06052.1 - 1.3 9.0 7.7 23 4.9 3.3 3.3 3 0 0 3 3 3 0 N-terminal region of micro-spherule protein SUIM_assoc PF16619.5 OEU06053.1 - 0.0036 17.3 7.1 1.4 9.0 0.1 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 XPG_I_2 PF12813.7 OEU06057.1 - 0.00077 19.0 0.3 0.00079 19.0 0.3 1.2 1 0 0 1 1 1 1 XPG domain containing Inhibitor_I48 PF10467.9 OEU06061.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Inhibitor_I48 PF10467.9 OEU06063.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin DUF2817 PF10994.8 OEU06066.1 - 1.7e-53 182.2 3.6 2.9e-44 151.9 3.2 3.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2817) NLRC4_HD PF17889.1 OEU06066.1 - 0.065 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 NLRC4 helical domain AstE_AspA PF04952.14 OEU06066.1 - 0.18 10.8 1.9 0.3 10.1 1.9 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family potato_inhibit PF00280.18 OEU06067.1 - 1.4e-06 28.9 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Potato inhibitor I family PSI PF01437.25 OEU06067.1 - 0.00025 21.5 6.9 0.00025 21.5 6.9 4.2 5 1 0 5 5 5 2 Plexin repeat PBP1_TM PF14812.6 OEU06067.1 - 6.9 7.1 8.6 1.2 9.6 0.4 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1275 PF06912.11 OEU06068.1 - 2.9e-11 43.7 1.7 4.2e-11 43.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sec62 PF03839.16 OEU06070.1 - 0.0033 17.0 2.4 0.004 16.7 2.4 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF4718 PF15842.5 OEU06070.1 - 0.03 14.1 4.3 0.046 13.5 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Zip PF02535.22 OEU06070.1 - 0.1 11.8 1.4 0.14 11.4 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmodium_Vir PF05795.11 OEU06070.1 - 0.2 11.1 4.0 0.24 10.8 4.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 OEU06070.1 - 0.4 9.7 3.9 0.42 9.6 3.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 OEU06070.1 - 0.52 8.4 4.5 0.6 8.2 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mitofilin PF09731.9 OEU06070.1 - 0.7 8.7 15.0 0.98 8.2 15.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Kei1 PF08552.11 OEU06070.1 - 0.99 9.3 8.3 2.8 7.8 8.3 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SAPS PF04499.15 OEU06070.1 - 2 7.1 6.9 2.3 6.9 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Orf78 PF06024.12 OEU06070.1 - 2.4 8.5 7.2 1.7e+02 2.5 7.2 2.2 1 1 0 1 1 1 0 Orf78 (ac78) NPR3 PF03666.13 OEU06070.1 - 2.6 6.7 8.2 3.1 6.5 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Acyl-CoA_dh_2 PF08028.11 OEU06070.1 - 8.4 6.7 9.6 0.62 10.3 4.9 1.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain zf-CDGSH PF09360.10 OEU06071.1 - 1.1e-08 35.2 0.1 2.1e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type MF_alpha_N PF05436.11 OEU06071.1 - 0.044 13.7 0.3 0.057 13.3 0.3 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Glyco_transf_41 PF13844.6 OEU06072.1 - 9.6e-09 34.2 0.1 1.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 41 Helicase_C_2 PF13307.6 OEU06072.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain CTP-dep_RFKase PF01982.16 OEU06072.1 - 0.1 12.7 0.1 9.4 6.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF120 Hist_deacetyl PF00850.19 OEU06077.1 - 2.9e-48 165.0 0.2 3.4e-48 164.7 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain zf-MYND PF01753.18 OEU06078.1 - 7.1e-06 26.0 16.0 1.3e-05 25.1 16.0 1.5 1 0 0 1 1 1 1 MYND finger HAD_2 PF13419.6 OEU06081.1 - 1.1e-14 54.9 0.0 2.8e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU06081.1 - 8.4e-09 36.0 0.0 8e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU06081.1 - 0.0015 19.0 0.1 0.0024 18.3 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sulfotransfer_2 PF03567.14 OEU06082.1 - 8.7e-11 42.2 0.1 1.8e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family JmjC PF02373.22 OEU06082.1 - 1.9e-05 25.1 0.5 0.00017 22.0 0.1 2.4 1 1 1 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 OEU06082.1 - 0.00048 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU06082.1 - 0.026 14.2 0.0 0.25 11.0 0.0 2.3 1 1 0 1 1 1 0 Cupin-like domain MHC_II_alpha PF00993.20 OEU06082.1 - 0.089 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Glucos_trans_II PF14264.6 OEU06082.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII PT PF04886.12 OEU06083.1 - 2.2e-16 59.1 55.7 1.8e+04 -8.2 54.9 3.9 1 1 0 1 1 1 0 PT repeat Methyltransf_23 PF13489.6 OEU06085.1 - 0.0006 19.7 0.0 0.0023 17.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU06085.1 - 0.0088 16.7 0.1 0.041 14.6 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF364 PF04016.12 OEU06085.1 - 0.0091 15.6 0.0 5 6.7 0.0 2.4 2 0 0 2 2 2 2 Putative heavy-metal chelation UPF0146 PF03686.13 OEU06085.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_12 PF08242.12 OEU06085.1 - 0.13 13.0 0.0 0.61 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 OEU06085.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain RRN3 PF05327.11 OEU06085.1 - 2.6 6.5 8.2 4.1 5.8 8.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tau95 PF09734.9 OEU06086.1 - 0.038 14.8 2.0 0.038 14.8 2.0 2.0 1 1 1 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain HYLS1_C PF15311.6 OEU06086.1 - 0.076 13.8 0.1 0.076 13.8 0.1 2.3 2 1 1 3 3 3 0 Hydrolethalus syndrome protein 1 C-terminus SAE2 PF08573.10 OEU06086.1 - 0.21 12.7 5.2 0.23 12.6 1.8 2.0 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2076 PF09849.9 OEU06086.1 - 1.6 8.7 10.6 1.1 9.3 6.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) FYDLN_acid PF09538.10 OEU06086.1 - 3.1 8.5 11.5 1.6 9.5 7.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PBP1_TM PF14812.6 OEU06086.1 - 3.5 8.1 9.7 0.62 10.5 5.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WRNPLPNID PF15017.6 OEU06086.1 - 3.9 8.4 10.8 1.7 9.6 6.6 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF4834 PF16118.5 OEU06086.1 - 5.5 8.0 10.6 4.8 8.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rotamase_3 PF13616.6 OEU06087.1 - 8.9e-12 45.6 0.1 9.2e-12 45.5 0.1 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OEU06087.1 - 7.1e-11 42.9 0.0 7.6e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU06087.1 - 0.037 14.9 0.0 0.037 14.9 0.0 1.0 1 0 0 1 1 1 0 PPIC-type PPIASE domain Mito_carr PF00153.27 OEU06088.1 - 2.3e-40 136.4 6.8 2.5e-17 62.6 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Cytochrome_cB PF11783.8 OEU06088.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial Rab5ip PF07019.12 OEU06088.1 - 1.3 9.7 4.5 1.3 9.7 0.9 2.7 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Ribonuc_L-PSP PF01042.21 OEU06089.1 - 1.2e-16 60.8 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP UvrD-helicase PF00580.21 OEU06090.1 - 2.7e-10 40.3 23.0 3.7e-10 39.8 0.1 3.8 3 1 1 4 4 4 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 OEU06090.1 - 8.7e-06 26.1 0.0 3.5e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OEU06090.1 - 6.6e-05 22.7 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Sigma54_activat PF00158.26 OEU06090.1 - 0.072 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Nucleotid_trans PF03407.16 OEU06091.1 - 2.7e-28 99.4 2.1 3.7e-28 99.0 2.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ThiP_synth PF10120.9 OEU06091.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine-phosphate synthase Nsp1_C PF05064.13 OEU06092.1 - 5.2e-15 55.3 0.1 2e-14 53.4 0.1 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region TSNAXIP1_N PF15739.5 OEU06092.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Laminin_II PF06009.12 OEU06092.1 - 0.48 10.4 2.2 9.7 6.2 0.2 2.4 1 1 1 2 2 2 0 Laminin Domain II ECH_1 PF00378.20 OEU06093.1 - 1.8e-76 256.8 0.2 2.1e-76 256.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU06093.1 - 1.2e-39 136.8 1.7 6.6e-35 121.2 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SLD5_C PF16922.5 OEU06095.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Peptidase_C65 PF10275.9 OEU06098.1 - 1.2e-46 159.2 0.0 1.7e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Thymidylat_synt PF00303.19 OEU06099.1 - 4.9e-114 380.0 0.0 6.6e-114 379.6 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 OEU06099.1 - 4.7e-26 91.4 0.0 7.7e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Dihydrofolate reductase TIG PF01833.24 OEU06099.1 - 0.043 13.9 0.3 0.1 12.7 0.3 1.6 1 1 0 1 1 1 0 IPT/TIG domain CENP-B_dimeris PF09026.10 OEU06099.1 - 0.043 14.2 1.8 0.22 11.9 2.4 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleotid_trans PF03407.16 OEU06100.1 - 2e-28 99.8 0.9 3.6e-28 99.0 0.9 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ATG22 PF11700.8 OEU06101.1 - 1.1e-14 53.9 32.1 2.6e-12 46.2 32.1 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OEU06101.1 - 9.5e-09 34.6 33.3 9.5e-09 34.6 33.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ATP-cone PF03477.16 OEU06102.1 - 0.19 12.3 2.5 0.62 10.7 0.2 2.6 3 0 0 3 3 3 0 ATP cone domain Myco_arth_vir_N PF09610.10 OEU06102.1 - 0.27 11.3 3.9 0.5 10.5 3.9 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) NAGPA PF09992.9 OEU06104.1 - 3.3e-25 89.2 5.0 2.8e-24 86.2 2.3 2.2 1 1 0 2 2 2 1 Phosphodiester glycosidase DUF3169 PF11368.8 OEU06104.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Macoilin PF09726.9 OEU06104.1 - 0.38 9.3 7.6 0.52 8.8 7.6 1.3 1 0 0 1 1 1 0 Macoilin family VEK-30 PF12107.8 OEU06105.1 - 0.066 13.1 2.2 0.14 12.1 2.2 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Leu_leader PF08054.11 OEU06105.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Leucine operon leader peptide HRDC PF00570.23 OEU06106.1 - 0.0051 16.8 2.6 0.006 16.5 0.1 2.4 3 0 0 3 3 3 1 HRDC domain Pox_Ag35 PF03286.14 OEU06106.1 - 2.1 8.1 11.4 0.29 10.9 6.7 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 OEU06108.1 - 0.86 9.1 13.5 1.2 8.6 13.5 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OEU06108.1 - 3.6 6.8 23.1 5.5 6.2 23.1 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OEU06108.1 - 6.3 4.8 23.2 7.7 4.5 23.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sec3_C PF09763.9 OEU06110.1 - 0.018 13.4 0.8 0.023 13.1 0.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 eIF3_N PF09440.10 OEU06110.1 - 0.073 13.5 1.8 0.11 13.0 1.8 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Methyltransf_10 PF05971.12 OEU06112.1 - 1.9e-83 280.3 0.0 2.5e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OEU06112.1 - 0.00068 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OEU06112.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OEU06112.1 - 0.15 12.7 0.0 2.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_7 PF03441.14 OEU06113.1 - 1.2e-55 188.1 1.8 2.4e-55 187.2 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OEU06113.1 - 3.5e-07 30.4 0.1 0.00088 19.3 0.0 3.6 3 0 0 3 3 3 2 DNA photolyase zf-RanBP PF00641.18 OEU06113.1 - 0.0037 16.6 1.8 0.0098 15.2 1.8 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Josephin PF02099.17 OEU06114.1 - 1.2e-36 126.3 0.0 1.4e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Josephin TRAUB PF08164.12 OEU06117.1 - 4.4e-22 78.4 1.1 6.6e-22 77.8 1.1 1.2 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal POX PF07526.11 OEU06117.1 - 0.097 13.2 0.2 0.12 12.9 0.2 1.2 1 0 0 1 1 1 0 Associated with HOX Transglut_core PF01841.19 OEU06118.1 - 5.3e-07 30.1 0.0 2.3e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily RCR PF12273.8 OEU06118.1 - 0.17 12.5 3.4 1.3 9.7 1.3 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Acetyltransf_1 PF00583.25 OEU06119.1 - 0.0082 16.4 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU06119.1 - 0.017 15.5 0.0 0.058 13.8 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fasciclin PF02469.22 OEU06120.1 - 7.8e-19 68.2 0.0 9.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DDE_Tnp_1_7 PF13843.6 OEU06121.1 - 2.3e-12 46.9 0.2 7.6e-12 45.2 0.2 1.8 1 1 0 1 1 1 1 Transposase IS4 AF-4 PF05110.13 OEU06122.1 - 0.02 13.0 20.2 0.024 12.8 20.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HATPase_c PF02518.26 OEU06123.1 - 2.4e-22 79.6 0.1 5.6e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OEU06123.1 - 4.4e-17 61.9 0.3 2.1e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GRIP PF01465.20 OEU06123.1 - 0.031 14.2 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 GRIP domain COP23 PF14218.6 OEU06123.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Metallophos PF00149.28 OEU06125.1 - 0.024 15.1 0.1 0.036 14.6 0.1 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase WW PF00397.26 OEU06126.1 - 8.7e-21 73.7 12.4 3.7e-11 42.9 1.5 2.3 2 0 0 2 2 2 2 WW domain DUF1631 PF07793.11 OEU06126.1 - 0.005 15.3 0.8 0.0059 15.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Pox_Ag35 PF03286.14 OEU06126.1 - 0.25 11.1 10.6 0.3 10.8 10.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 OEU06126.1 - 1.7 7.7 21.9 2.3 7.3 21.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 OEU06126.1 - 2.3 8.0 10.7 2.5 7.9 10.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Chloroa_b-bind PF00504.21 OEU06127.1 - 2.7e-20 73.5 0.0 4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein fragilysinNterm PF16376.5 OEU06128.1 - 0.036 13.8 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of fragilysin DUF4448 PF14610.6 OEU06128.1 - 0.069 12.9 0.7 0.082 12.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rtf2 PF04641.12 OEU06128.1 - 3.5 6.9 9.0 4.3 6.6 9.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger AP3D1 PF06375.11 OEU06128.1 - 4.2 7.6 8.6 1.6 9.0 5.9 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 TPR_2 PF07719.17 OEU06129.1 - 0.00065 19.6 0.2 0.03 14.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU06129.1 - 0.0078 16.0 4.0 0.65 9.9 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Miff PF05644.11 OEU06129.1 - 0.019 14.6 4.4 0.64 9.6 1.8 2.3 1 1 1 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff MAS20 PF02064.15 OEU06129.1 - 0.026 14.6 0.7 0.052 13.6 0.7 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor SID-1_RNA_chan PF13965.6 OEU06129.1 - 0.041 12.3 1.7 0.041 12.3 1.1 1.2 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 FAM176 PF14851.6 OEU06129.1 - 0.25 11.0 2.1 0.29 10.8 1.2 1.6 1 1 0 1 1 1 0 FAM176 family Presenilin PF01080.17 OEU06129.1 - 0.39 9.4 4.6 0.42 9.3 4.6 1.3 1 0 0 1 1 1 0 Presenilin DUF3552 PF12072.8 OEU06129.1 - 0.48 9.8 7.1 0.29 10.5 5.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Neur_chan_memb PF02932.16 OEU06129.1 - 0.56 10.2 3.3 0.84 9.6 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 OEU06129.1 - 0.56 9.4 2.6 0.65 9.2 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LCM PF04072.14 OEU06130.1 - 4.5e-12 46.3 0.0 1.1e-09 38.5 0.0 2.0 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase Ribosomal_S16 PF00886.19 OEU06131.1 - 1.1e-18 67.0 0.1 1.3e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 DUF2719 PF10891.8 OEU06133.1 - 0.13 12.1 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Cu-oxidase_2 PF07731.14 OEU06134.1 - 6.2e-38 129.6 11.7 1.3e-35 122.2 0.3 3.7 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OEU06134.1 - 3.1e-30 105.4 0.2 1.2e-29 103.5 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OEU06134.1 - 3.3e-29 101.3 9.2 8.6e-29 100.0 1.4 3.4 3 0 0 3 3 3 2 Multicopper oxidase Methyltransf_24 PF13578.6 OEU06135.1 - 3.8e-07 31.1 0.0 9.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Nop14 PF04147.12 OEU06143.1 - 6.3 4.9 11.1 7.6 4.6 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.25 OEU06144.1 - 4.2e-07 30.2 0.2 4.9e-05 23.5 0.1 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OEU06144.1 - 0.00025 21.1 0.0 0.0007 19.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU06144.1 - 0.0018 18.6 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OEU06144.1 - 0.0059 16.6 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.7 OEU06144.1 - 0.011 15.6 0.0 0.032 14.2 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU06144.1 - 0.13 12.3 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein AAA_21 PF13304.6 OEU06144.1 - 0.8 9.5 6.5 1.3 8.8 6.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_C14 PF00656.22 OEU06145.1 - 2.2e-43 149.0 1.3 4.3e-32 112.0 0.5 2.0 2 0 0 2 2 2 2 Caspase domain Dirigent PF03018.14 OEU06146.1 - 0.0092 15.8 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 Dirigent-like protein HA PF03457.14 OEU06147.1 - 8.7e-16 58.0 0.2 6.9e-15 55.1 0.2 2.4 2 0 0 2 2 2 1 Helicase associated domain Utp14 PF04615.13 OEU06147.1 - 1.3 7.5 34.7 2.2 6.8 34.7 1.2 1 0 0 1 1 1 0 Utp14 protein SRA1 PF07304.11 OEU06149.1 - 0.22 11.3 3.0 10 5.9 0.1 2.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Yae1_N PF09811.9 OEU06151.1 - 1.4e-05 24.7 78.5 0.27 11.0 0.1 16.9 8 5 6 14 14 14 12 Essential protein Yae1, N terminal ATG22 PF11700.8 OEU06152.1 - 1.1e-24 87.0 31.4 3.7e-23 81.9 31.4 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OEU06152.1 - 1.1e-09 37.7 30.2 1.1e-09 37.7 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 OEU06153.1 - 0.047 13.2 11.8 0.076 12.5 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Abhydrolase_9_N PF15420.6 OEU06153.1 - 0.96 9.4 6.4 0.49 10.4 2.4 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Rhomboid PF01694.22 OEU06153.1 - 4 7.4 17.3 0.075 13.0 5.1 3.2 2 1 1 3 3 3 0 Rhomboid family CPP1-like PF11833.8 OEU06153.1 - 6.3 6.4 6.3 5.9 6.5 1.1 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF872 PF05915.12 OEU06153.1 - 8.5 6.6 10.8 10 6.3 4.1 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TssN PF17555.2 OEU06153.1 - 8.9 5.6 19.2 0.91 8.8 2.2 3.3 1 1 0 3 3 3 0 Type VI secretion system, TssN HA PF03457.14 OEU06154.1 - 6.7e-50 167.3 3.6 1.5e-15 57.3 0.1 3.1 3 0 0 3 3 3 3 Helicase associated domain Ank_5 PF13857.6 OEU06155.1 - 0.0029 17.9 0.0 0.69 10.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU06155.1 - 0.051 14.2 0.0 0.27 11.9 0.0 2.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) LRR_4 PF12799.7 OEU06156.1 - 3.7e-06 27.2 18.8 0.038 14.4 2.4 5.5 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) Rota_NS6 PF04866.12 OEU06156.1 - 0.0033 17.6 1.7 4.2 7.6 0.4 3.3 3 0 0 3 3 3 2 Rotavirus non-structural protein 6 LRR_6 PF13516.6 OEU06156.1 - 0.02 14.9 2.3 4.9 7.5 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 OEU06156.1 - 0.028 13.9 5.1 0.15 11.6 1.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 OEU06156.1 - 0.13 12.0 12.6 0.26 11.1 0.2 4.4 5 2 0 5 5 5 0 Leucine rich repeat Bclt PF15318.6 OEU06158.1 - 0.57 10.0 4.9 4.2 7.1 0.0 2.8 2 1 1 3 3 3 0 Putative Bcl-2 like protein of testis DDE_Tnp_1_7 PF13843.6 OEU06161.1 - 0.00044 19.7 0.3 0.022 14.0 0.0 2.8 2 1 0 2 2 2 2 Transposase IS4 Cyto_heme_lyase PF01265.17 OEU06162.1 - 5.8e-52 177.1 8.6 8.4e-51 173.3 8.6 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF3768 PF12599.8 OEU06162.1 - 0.066 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) Pyr_redox_2 PF07992.14 OEU06165.1 - 1.6e-29 103.1 0.2 2.2e-29 102.6 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU06165.1 - 7.6e-11 42.4 0.1 1.4e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU06165.1 - 9.1e-10 38.8 0.1 3.1e-09 37.1 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 OEU06165.1 - 8.3e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU06165.1 - 5.5e-05 22.4 0.1 0.0024 17.1 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OEU06165.1 - 0.0026 18.2 0.5 0.0092 16.4 0.1 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OEU06165.1 - 0.0047 16.3 0.2 0.0098 15.2 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OEU06165.1 - 0.0066 16.3 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OEU06165.1 - 0.0072 15.6 0.8 0.012 14.8 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4392 PF14336.6 OEU06165.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) FAD_binding_2 PF00890.24 OEU06165.1 - 0.0099 15.0 2.3 0.19 10.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DFP PF04127.15 OEU06165.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Lycopene_cycl PF05834.12 OEU06165.1 - 0.015 14.3 0.7 0.023 13.8 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 OEU06165.1 - 0.05 13.8 0.4 0.17 12.1 0.4 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_transf_4 PF13439.6 OEU06165.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ThiF PF00899.21 OEU06165.1 - 0.19 11.1 1.5 0.3 10.4 0.4 1.9 1 1 1 2 2 2 0 ThiF family DAO PF01266.24 OEU06165.1 - 0.23 11.0 1.1 0.4 10.2 1.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase BTB_2 PF02214.22 OEU06166.1 - 1.2e-08 35.1 0.1 7.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Pyridoxal_deC PF00282.19 OEU06167.1 - 8.1e-46 156.4 0.0 8.9e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4461 PF14688.6 OEU06168.1 - 0.084 12.6 0.1 0.098 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) TTD PF12148.8 OEU06169.1 - 0.00094 19.1 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 Lig_chan PF00060.26 OEU06170.1 - 1.3e-08 34.8 0.1 1.3e-07 31.6 0.0 3.1 2 1 0 2 2 2 1 Ligand-gated ion channel DUF4692 PF15763.5 OEU06170.1 - 0.024 15.1 0.3 0.065 13.7 0.3 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF2381 PF09544.10 OEU06170.1 - 0.041 13.4 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DUF780 PF05611.11 OEU06171.1 - 0.024 15.4 1.7 0.07 13.9 1.7 1.8 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF3560 PF12083.8 OEU06171.1 - 2.2 8.4 13.3 0.14 12.3 5.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Tetraspanin PF00335.20 OEU06173.1 - 0.57 9.8 3.0 0.34 10.6 0.3 1.8 2 0 0 2 2 2 0 Tetraspanin family O-FucT PF10250.9 OEU06174.1 - 2.5e-06 27.4 0.1 7.4e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SpoIIIAH PF12685.7 OEU06174.1 - 0.018 14.9 2.6 0.018 14.9 2.6 3.5 2 2 1 3 3 3 0 SpoIIIAH-like protein GTP_EFTU PF00009.27 OEU06176.1 - 4.3e-26 91.6 2.2 5.2e-26 91.4 2.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OEU06176.1 - 0.00018 21.5 1.2 0.0027 17.8 1.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OEU06176.1 - 0.00035 20.1 0.5 0.011 15.2 0.5 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 OEU06176.1 - 0.0056 16.0 1.2 0.0093 15.3 1.2 1.3 1 1 0 1 1 1 1 Septin MobB PF03205.14 OEU06176.1 - 0.068 13.1 0.1 0.088 12.7 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRiA4_ORF3 PF07929.11 OEU06177.1 - 5.1e-13 49.1 0.0 8.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Ank_2 PF12796.7 OEU06178.1 - 1.5e-15 57.6 0.0 2.5e-08 34.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU06178.1 - 1.4e-13 50.7 0.1 0.00024 21.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OEU06178.1 - 4.7e-12 45.0 0.0 0.00076 19.7 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OEU06178.1 - 8.1e-11 42.0 0.1 0.0021 18.3 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU06178.1 - 6e-08 33.1 0.0 0.0091 16.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PEPcase PF00311.17 OEU06179.1 - 2.2e-38 131.9 0.0 3.2e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase DUF3965 PF13112.6 OEU06179.1 - 0.06 12.5 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3965) Fe_hyd_SSU PF02256.17 OEU06179.1 - 0.077 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Iron hydrogenase small subunit Fasciclin PF02469.22 OEU06180.1 - 2.1e-18 66.8 0.0 3.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain PPR_1 PF12854.7 OEU06181.1 - 1e-26 92.3 0.0 2e-05 24.2 0.0 7.3 6 2 0 6 6 6 6 PPR repeat PPR_2 PF13041.6 OEU06181.1 - 2.9e-20 72.2 4.8 4.6e-05 23.5 0.1 6.6 4 2 1 5 5 5 5 PPR repeat family PPR_3 PF13812.6 OEU06181.1 - 1.8e-16 59.9 0.2 0.00053 20.0 0.0 5.6 3 1 2 5 5 5 5 Pentatricopeptide repeat domain PPR PF01535.20 OEU06181.1 - 1.8e-14 52.9 6.7 0.0047 17.1 0.0 7.2 5 4 0 5 5 5 4 PPR repeat PPR_long PF17177.4 OEU06181.1 - 2.4e-05 23.8 0.8 0.0007 19.0 0.3 2.5 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP DUF3168 PF11367.8 OEU06181.1 - 0.0049 17.0 0.1 0.47 10.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3168) Wzy_C_2 PF11846.8 OEU06181.1 - 0.07 13.1 0.8 6.5 6.6 0.0 3.1 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal HisG_C PF08029.11 OEU06183.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 HisG, C-terminal domain Exostosin PF03016.15 OEU06187.1 - 3.2e-18 66.0 0.0 3.5e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Exostosin family Cystatin PF00031.21 OEU06189.1 - 2.6e-09 37.2 0.1 3.1e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 OEU06189.1 - 0.0022 18.3 0.3 0.0029 17.9 0.3 1.2 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor HMA PF00403.26 OEU06190.1 - 0.0027 18.1 0.7 0.0067 16.8 0.7 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain SKA2 PF16740.5 OEU06191.1 - 3.9e-07 29.8 1.7 1.1e-06 28.4 1.7 1.6 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Phage-scaffold PF09306.10 OEU06192.1 - 0.00081 18.8 1.5 0.0014 18.1 1.5 1.3 1 0 0 1 1 1 1 Bacteriophage, scaffolding protein Podoplanin PF05808.11 OEU06192.1 - 0.036 14.2 0.3 0.092 12.9 0.3 1.6 1 0 0 1 1 1 0 Podoplanin Nterm_IS4 PF13006.7 OEU06192.1 - 0.07 13.3 0.3 20 5.5 0.0 2.5 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal URO-D PF01208.17 OEU06195.1 - 4.4e-11 42.5 0.0 6.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) YnfE PF17452.2 OEU06195.1 - 0.0052 17.0 0.2 0.011 16.0 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized YnfE-like Hydrolase_3 PF08282.12 OEU06197.1 - 1.2e-38 133.4 0.0 2.4e-38 132.3 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OEU06197.1 - 2.6e-07 30.5 0.0 3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 OEU06197.1 - 0.00017 22.0 0.0 0.0011 19.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HisK_sensor PF18698.1 OEU06197.1 - 0.2 12.0 1.8 7.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Histidine kinase sensor domain zf-MYND PF01753.18 OEU06199.1 - 1.7e-06 28.0 17.9 1.7e-06 28.0 17.9 2.2 2 0 0 2 2 2 1 MYND finger FYVE PF01363.21 OEU06200.1 - 2.7e-17 62.7 7.2 2.8e-17 62.6 7.2 1.0 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 OEU06200.1 - 0.0044 17.3 6.9 0.0059 16.9 6.9 1.2 1 0 0 1 1 1 1 Ring finger domain FYVE_2 PF02318.16 OEU06200.1 - 0.0085 16.3 3.4 0.0085 16.3 3.4 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C2HC5 PF06221.13 OEU06200.1 - 0.25 11.4 8.5 1.2 9.2 2.8 2.1 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_4 PF13894.6 OEU06200.1 - 1.8 9.6 11.9 16 6.6 3.7 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Drc1-Sld2 PF11719.8 OEU06201.1 - 0.024 14.2 5.2 0.023 14.2 5.2 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein RRN3 PF05327.11 OEU06201.1 - 1.2 7.6 9.4 1.1 7.7 9.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_tran PF00005.27 OEU06203.1 - 4.3e-23 82.3 4.1 2.5e-14 53.9 0.1 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OEU06203.1 - 1.7e-07 31.3 2.9 0.03 14.1 0.5 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU06203.1 - 2.1e-05 24.0 7.7 0.00039 19.9 0.2 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU06203.1 - 6.8e-05 23.3 1.6 0.00027 21.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 OEU06203.1 - 0.00061 19.7 0.2 0.1 12.5 0.2 2.6 2 0 0 2 2 2 1 NTPase RsgA_GTPase PF03193.16 OEU06203.1 - 0.0007 19.5 2.1 0.0043 17.0 0.0 2.6 1 1 0 2 2 2 1 RsgA GTPase CCDC144C PF14915.6 OEU06203.1 - 0.002 17.3 6.6 0.0032 16.6 6.6 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region NACHT PF05729.12 OEU06203.1 - 0.0024 17.8 0.9 0.0097 15.8 0.9 2.1 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 OEU06203.1 - 0.0032 17.2 0.0 0.0087 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1515 PF07439.11 OEU06203.1 - 0.012 15.7 1.2 0.027 14.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) RuvB_N PF05496.12 OEU06203.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU06203.1 - 0.031 14.8 0.8 0.53 10.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 OEU06203.1 - 0.038 13.7 0.3 2.9 7.6 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein OmpH PF03938.14 OEU06203.1 - 0.04 14.2 6.6 0.13 12.6 7.2 1.5 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) AAA_14 PF13173.6 OEU06203.1 - 0.043 13.9 0.1 0.67 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OEU06203.1 - 0.055 13.5 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU06203.1 - 0.062 13.6 1.9 0.3 11.3 0.2 3.0 3 1 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OEU06203.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 OEU06203.1 - 0.067 13.0 7.4 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 OEU06203.1 - 0.088 12.4 4.6 0.14 11.7 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.23 OEU06203.1 - 0.094 12.8 0.8 0.46 10.6 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 OEU06203.1 - 0.1 13.0 3.9 0.24 11.8 0.3 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ax_dynein_light PF10211.9 OEU06203.1 - 0.23 11.4 7.7 0.37 10.7 7.7 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain RNA_helicase PF00910.22 OEU06203.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.8 4 0 0 4 4 2 0 RNA helicase CENP-H PF05837.12 OEU06203.1 - 0.32 11.4 11.8 1 9.8 11.8 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_23 PF13476.6 OEU06203.1 - 2.5 8.6 15.4 0.25 11.8 0.4 2.5 1 1 1 2 2 2 0 AAA domain SOAR PF16533.5 OEU06203.1 - 8 6.5 10.1 20 5.2 4.9 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region Methyltransf_16 PF10294.9 OEU06206.1 - 2.8e-18 66.2 3.8 1.7e-16 60.5 3.8 2.6 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OEU06206.1 - 7.9e-05 22.2 0.2 0.00019 20.9 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU06206.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF4469 PF14734.6 OEU06206.1 - 0.036 14.2 1.3 1.1 9.5 0.1 3.0 1 1 0 3 3 3 0 Domain of unknown function (DUF4469) with IG-like fold PH_4 PF15404.6 OEU06206.1 - 0.056 13.2 1.1 0.12 12.2 1.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SelP_N PF04592.14 OEU06206.1 - 0.4 10.0 6.5 0.95 8.8 3.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region BAP PF06639.11 OEU06206.1 - 0.69 10.3 4.9 1.8 9.0 0.4 2.9 2 1 1 3 3 3 0 Basal layer antifungal peptide (BAP) zf-MYND PF01753.18 OEU06207.1 - 1.4e-06 28.3 16.8 1.4e-06 28.3 15.4 1.8 2 0 0 2 2 2 1 MYND finger Peptidase_M16_M PF16187.5 OEU06209.1 - 2.1e-72 243.8 0.1 3.5e-72 243.0 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OEU06209.1 - 9.3e-40 136.0 0.0 3.3e-38 131.0 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU06209.1 - 1.3e-17 64.4 0.9 4.3e-13 49.7 0.2 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain CENP-B_dimeris PF09026.10 OEU06210.1 - 0.0071 16.7 0.4 0.011 16.1 0.4 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain FSAP_sig_propep PF03032.15 OEU06210.1 - 0.17 12.0 1.8 0.35 10.9 1.8 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide GCR1_C PF12550.8 OEU06211.1 - 4.2e-05 23.8 0.3 0.00028 21.1 0.0 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Peptidase_C10 PF01640.17 OEU06211.1 - 0.54 10.6 2.0 31 4.8 0.1 3.1 3 0 0 3 3 3 0 Peptidase C10 family DUF285 PF03382.14 OEU06212.1 - 9.7e-96 315.9 94.5 2.4e-22 78.9 13.7 5.3 1 1 4 5 5 5 5 Mycoplasma protein of unknown function, DUF285 FTH PF01827.27 OEU06212.1 - 0.065 13.0 4.7 1.4 8.7 0.2 2.8 2 1 1 3 3 3 0 FTH domain DUF2534 PF10749.9 OEU06212.1 - 1.2 9.3 3.4 27 5.0 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2534) FAM60A PF15396.6 OEU06213.1 - 0.35 10.8 6.5 0.52 10.3 6.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Phage_holin_2_4 PF16082.5 OEU06213.1 - 0.42 10.4 5.1 0.87 9.4 5.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like K_channel_TID PF07941.11 OEU06214.1 - 0.029 14.8 0.4 0.029 14.8 0.4 3.9 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain IFT20 PF14931.6 OEU06214.1 - 0.49 10.6 20.7 3.1 8.0 4.1 3.2 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 ZapB PF06005.12 OEU06214.1 - 7.4 7.1 18.3 2.1 8.9 3.0 3.7 3 0 0 3 3 3 0 Cell division protein ZapB Yae1_N PF09811.9 OEU06215.1 - 3.5e-09 36.2 55.8 0.068 12.9 1.7 12.8 6 5 5 11 11 11 10 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU06215.1 - 0.048 13.8 0.0 37 4.4 0.1 3.9 1 1 2 3 3 3 0 Outer membrane protein beta-barrel domain Squash PF00299.18 OEU06216.1 - 0.00085 19.3 1.6 0.00085 19.3 1.6 2.2 2 0 0 2 2 2 1 Squash family serine protease inhibitor Methyltransf_16 PF10294.9 OEU06219.1 - 3.2e-20 72.6 2.5 3.9e-15 56.0 0.7 2.5 2 1 0 2 2 2 2 Lysine methyltransferase Orthoreo_P17 PF07272.11 OEU06219.1 - 0.0076 16.3 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 Orthoreovirus P17 protein MTS PF05175.14 OEU06219.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 OEU06219.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4536 PF15055.6 OEU06219.1 - 0.04 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Methyltransf_12 PF08242.12 OEU06219.1 - 0.11 13.2 3.6 0.61 10.9 0.0 3.2 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 OEU06219.1 - 0.15 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GDPD PF03009.17 OEU06220.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Hydin_ADK PF17213.3 OEU06221.1 - 0.65 10.2 13.4 1 9.6 13.3 1.3 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Rgp1 PF08737.10 OEU06221.1 - 1.4 8.0 11.6 1.8 7.6 11.6 1.1 1 0 0 1 1 1 0 Rgp1 SOBP PF15279.6 OEU06221.1 - 1.9 9.1 8.4 2.2 8.8 8.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 OEU06221.1 - 4.7 4.2 10.8 5.5 4.0 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 OEU06221.1 - 6.1 5.0 14.2 7.1 4.8 14.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3818 PF12825.7 OEU06221.1 - 7.7 5.4 10.4 8.8 5.2 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) zf-MYND PF01753.18 OEU06222.1 - 3.6e-06 27.0 7.9 7.8e-06 25.9 7.9 1.6 1 0 0 1 1 1 1 MYND finger DUF3449 PF11931.8 OEU06222.1 - 0.0086 15.9 0.2 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Fasciclin PF02469.22 OEU06223.1 - 2e-16 60.4 4.1 2.7e-11 43.8 0.1 3.8 4 0 0 4 4 4 3 Fasciclin domain GCIP PF13324.6 OEU06223.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ank_5 PF13857.6 OEU06224.1 - 0.16 12.3 0.6 4.7 7.6 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) ubiquitin PF00240.23 OEU06226.1 - 2.6e-21 75.1 0.2 2.8e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU06226.1 - 9.7e-10 38.1 0.1 1e-09 38.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OEU06226.1 - 0.0014 19.0 0.2 0.0014 19.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU06226.1 - 0.0033 17.5 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU06226.1 - 0.0088 16.5 0.1 0.054 14.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU06226.1 - 0.063 13.2 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain adh_short PF00106.25 OEU06227.1 - 1.1e-11 44.6 3.8 4.3e-07 29.6 2.3 4.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OEU06227.1 - 0.0013 18.7 0.0 0.0033 17.3 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 OEU06227.1 - 0.0099 15.4 1.2 0.55 9.7 0.2 3.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OEU06227.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding MARVEL PF01284.23 OEU06227.1 - 0.18 11.9 4.7 0.15 12.1 1.7 2.4 2 1 0 2 2 2 0 Membrane-associating domain DUF4029 PF13221.6 OEU06227.1 - 4.1 8.1 8.9 2.6 8.8 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Ank_2 PF12796.7 OEU06228.1 - 0.028 15.0 0.0 3.4 8.3 0.0 2.6 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) DUF1129 PF06570.11 OEU06230.1 - 1.6 8.2 12.2 12 5.3 2.9 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) DUF1772 PF08592.11 OEU06230.1 - 1.9 8.8 5.7 17 5.7 4.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2873 PF11395.8 OEU06230.1 - 2 8.3 6.2 19 5.2 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) Pes-10 PF07149.11 OEU06230.1 - 6.8 5.6 6.6 9.9 5.1 6.6 1.2 1 0 0 1 1 1 0 Pes-10 WD40 PF00400.32 OEU06231.1 - 2.8e-08 34.3 6.8 4.5e-07 30.4 0.2 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU06231.1 - 3.7e-06 27.1 0.0 0.00013 22.2 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 OEU06231.1 - 0.045 13.3 0.0 0.23 11.0 0.0 2.1 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 OEU06231.1 - 0.08 11.9 0.0 0.59 9.0 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Retrotran_gag_2 PF14223.6 OEU06232.1 - 0.0038 16.9 3.7 0.0087 15.7 0.1 2.5 1 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4407 PF14362.6 OEU06232.1 - 1.3 8.3 6.2 2.2 7.5 5.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Vps55 PF04133.14 OEU06233.1 - 0.061 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DUF4834 PF16118.5 OEU06233.1 - 0.19 12.7 3.4 0.44 11.5 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 OEU06233.1 - 0.97 9.8 3.3 1.8 8.9 0.6 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 OEU06235.1 - 1.7 8.3 0.0 1.7 8.3 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Ank_2 PF12796.7 OEU06236.1 - 0.00014 22.4 0.1 0.075 13.6 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU06236.1 - 0.00025 21.5 0.0 1.4 9.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) eIF-3c_N PF05470.12 OEU06237.1 - 0.0099 14.2 4.1 0.013 13.9 4.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 OEU06237.1 - 0.017 13.4 3.7 0.019 13.2 3.7 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 OEU06237.1 - 0.023 14.3 3.1 0.031 13.9 3.1 1.2 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 OEU06237.1 - 0.2 10.2 5.1 0.24 9.9 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 OEU06237.1 - 0.33 9.2 6.0 0.36 9.1 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OEU06237.1 - 2.8 6.4 7.4 3.1 6.2 7.4 1.0 1 0 0 1 1 1 0 Macoilin family Sporozoite_P67 PF05642.11 OEU06237.1 - 2.9 5.9 6.2 3.2 5.7 6.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 OEU06237.1 - 3 7.1 10.7 3.8 6.7 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_2 PF12796.7 OEU06238.1 - 6.4e-05 23.5 0.0 0.54 10.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU06238.1 - 0.00024 21.6 0.0 1.3 9.7 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU06238.1 - 0.054 14.1 0.0 68 4.5 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat Acetyltransf_1 PF00583.25 OEU06239.1 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HA PF03457.14 OEU06241.1 - 3.6e-46 155.3 0.9 2.2e-16 59.9 0.1 3.1 3 0 0 3 3 3 3 Helicase associated domain Ribosomal_L6e_N PF03868.15 OEU06241.1 - 0.039 14.2 1.1 11 6.4 0.0 3.4 4 0 0 4 4 4 0 Ribosomal protein L6, N-terminal domain LRR_4 PF12799.7 OEU06246.1 - 0.056 13.9 6.8 3.7 8.1 0.3 4.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) PRKCSH-like PF12999.7 OEU06247.1 - 2.9e-05 24.0 0.4 4.5e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Internalin_N PF12354.8 OEU06247.1 - 0.068 13.3 0.2 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal AstB PF04996.12 OEU06247.1 - 0.19 10.4 0.6 0.23 10.1 0.6 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase zf-MYND PF01753.18 OEU06248.1 - 1.5e-05 25.0 15.8 2.9e-05 24.0 15.8 1.5 1 0 0 1 1 1 1 MYND finger SET PF00856.28 OEU06249.1 - 6.2e-15 56.0 0.2 6.2e-15 56.0 0.2 2.8 3 1 0 3 3 3 1 SET domain Cas_GSU0054 PF09609.10 OEU06249.1 - 0.092 11.4 0.4 0.17 10.5 0.4 1.4 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) P53_TAD PF08563.11 OEU06251.1 - 0.063 12.8 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P53 transactivation motif C2 PF00168.30 OEU06252.1 - 2.1e-17 63.3 0.0 1.4e-11 44.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain Otopetrin PF03189.13 OEU06256.1 - 0.00035 19.5 0.0 0.00053 18.9 0.0 1.3 1 0 0 1 1 1 1 Otopetrin DUF3575 PF12099.8 OEU06256.1 - 0.0013 18.0 0.1 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3575) OTU PF02338.19 OEU06257.1 - 4.1e-08 33.8 0.0 8.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OEU06257.1 - 0.00062 19.3 0.2 0.043 13.3 0.0 2.7 1 1 1 2 2 2 2 Peptidase C65 Otubain NUP50 PF08911.11 OEU06257.1 - 0.0076 16.9 0.6 0.0076 16.9 0.6 2.8 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) PE PF00934.20 OEU06257.1 - 0.29 11.5 20.4 1.5 9.2 11.0 2.7 2 0 0 2 2 2 0 PE family 2OG-FeII_Oxy_2 PF13532.6 OEU06259.1 - 2.8e-13 50.5 0.3 4.8e-13 49.7 0.3 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.14 OEU06259.1 - 4.5 5.5 12.7 5.7 5.1 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OEU06259.1 - 6.9 5.1 11.4 8.5 4.8 11.4 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OEU06259.1 - 7.4 5.2 7.8 9.8 4.8 7.8 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 OEU06259.1 - 9 4.5 9.8 13 4.0 9.8 1.1 1 0 0 1 1 1 0 Menin CENP-B_dimeris PF09026.10 OEU06260.1 - 0.034 14.5 10.8 2.1 8.8 0.1 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF2116 PF09889.9 OEU06260.1 - 0.34 10.9 1.3 0.55 10.3 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SUIM_assoc PF16619.5 OEU06260.1 - 1.1 9.3 9.9 0.55 10.3 1.1 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4611 PF15387.6 OEU06260.1 - 1.4 9.2 11.7 2.2 8.6 2.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Miga PF10265.9 OEU06260.1 - 2.8 6.8 15.9 0.81 8.6 4.9 2.2 2 0 0 2 2 2 0 Mitoguardin DUF5505 PF17610.2 OEU06261.1 - 3e-05 24.1 0.6 14 5.6 0.0 4.0 1 1 3 4 4 4 4 Family of unknown function (DUF5505) TSNR_N PF04705.12 OEU06261.1 - 0.1 12.7 0.0 2.6e+02 1.7 0.0 3.9 4 0 0 4 4 4 0 Thiostrepton-resistance methylase, N terminus Acetyltransf_1 PF00583.25 OEU06262.1 - 6.6e-06 26.3 0.0 0.047 13.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 OEU06262.1 - 0.0052 16.7 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 OEU06262.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU06262.1 - 0.042 13.8 0.0 0.36 10.8 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain HA PF03457.14 OEU06263.1 - 5.6e-58 193.1 2.7 5.4e-19 68.3 0.1 3.1 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU06263.1 - 0.0048 17.0 0.4 2 8.5 0.0 3.3 3 0 0 3 3 3 1 Transcriptional regulation of mitochondrial recombination MNR PF15718.5 OEU06267.1 - 0.016 13.4 0.3 0.018 13.3 0.3 1.0 1 0 0 1 1 1 0 Protein moonraker PK PF00224.21 OEU06268.1 - 4.7e-32 111.2 0.0 5.8e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain IMPDH PF00478.25 OEU06268.1 - 0.032 13.2 0.0 0.18 10.7 0.0 1.8 1 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Nucleoside_tran PF01733.18 OEU06269.1 - 7.6e-05 22.2 2.8 0.0046 16.4 1.4 2.3 1 1 1 2 2 2 2 Nucleoside transporter Peptidase_C1 PF00112.23 OEU06270.1 - 3.2e-07 30.7 0.0 4.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 OEU06271.1 - 5.3e-15 56.1 0.6 7.5e-15 55.6 0.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease zf-RING_2 PF13639.6 OEU06274.1 - 5.1e-10 39.5 5.6 5.9e-07 29.7 2.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 OEU06274.1 - 1.1e-07 31.8 2.1 2.6e-07 30.5 2.1 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU06274.1 - 3.5e-07 30.2 0.6 1.5e-05 25.0 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OEU06274.1 - 7e-07 29.4 7.0 3.1e-06 27.4 7.0 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU06274.1 - 1e-06 28.5 8.6 8.5e-06 25.5 3.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU06274.1 - 1.4e-06 28.0 4.4 8.7e-06 25.5 4.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU06274.1 - 7.2e-06 25.6 8.8 0.021 14.6 5.8 2.7 2 1 0 2 2 2 2 RING-like zinc finger zf-Nse PF11789.8 OEU06274.1 - 8e-05 22.4 0.7 8e-05 22.4 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 OEU06274.1 - 0.00013 21.5 2.3 0.00013 21.5 2.3 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OEU06274.1 - 0.0017 18.3 2.2 0.03 14.3 1.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 OEU06274.1 - 0.0039 17.2 1.9 0.02 14.9 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger RINGv PF12906.7 OEU06274.1 - 0.0057 16.8 1.1 0.0057 16.8 1.1 2.0 2 0 0 2 2 2 1 RING-variant domain FANCL_C PF11793.8 OEU06274.1 - 0.0072 16.5 4.1 0.034 14.3 4.1 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain RecR PF02132.15 OEU06274.1 - 0.095 12.3 1.1 0.21 11.2 1.1 1.5 1 0 0 1 1 1 0 RecR protein zf-C3HC4_3 PF13920.6 OEU06274.1 - 0.12 12.2 3.4 7.1 6.6 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU06274.1 - 0.15 12.2 6.3 0.57 10.4 0.7 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OEU06274.1 - 3.7 7.9 7.5 0.26 11.6 2.5 1.6 2 0 0 2 2 1 0 RING-like domain PBP1_TM PF14812.6 OEU06275.1 - 0.02 15.3 3.5 1.7 9.1 0.1 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med21 PF11221.8 OEU06275.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.2 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Orf78 PF06024.12 OEU06275.1 - 0.54 10.6 0.0 0.54 10.6 0.0 3.5 3 1 0 3 3 3 0 Orf78 (ac78) HAMP PF00672.25 OEU06276.1 - 0.011 16.1 0.0 0.042 14.2 0.0 2.1 1 1 0 1 1 1 0 HAMP domain TPR_12 PF13424.6 OEU06276.1 - 0.076 13.3 0.2 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ECSCR PF15820.5 OEU06276.1 - 2.5 8.0 5.6 5.1 7.0 0.3 3.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DDE_Tnp_1_7 PF13843.6 OEU06277.1 - 2.3e-17 63.4 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 RRM_1 PF00076.22 OEU06278.1 - 2.4e-14 52.9 0.1 3.6e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 OEU06278.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 OEU06278.1 - 0.016 15.2 0.1 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OEU06278.1 - 0.038 14.0 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif Exostosin PF03016.15 OEU06279.1 - 0.0011 18.3 0.0 0.019 14.2 0.0 2.1 1 1 1 2 2 2 2 Exostosin family MerR PF00376.23 OEU06279.1 - 0.024 14.4 0.1 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 MerR family regulatory protein HIT PF01230.23 OEU06280.1 - 1.3e-16 61.1 0.1 4.1e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 OEU06280.1 - 0.0015 19.0 0.6 0.0079 16.7 0.1 1.9 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HNH_2 PF13391.6 OEU06280.1 - 0.088 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 HNH endonuclease HA PF03457.14 OEU06281.1 - 3.8e-25 88.0 1.0 7.1e-12 45.5 0.2 2.3 2 0 0 2 2 2 2 Helicase associated domain DUF285 PF03382.14 OEU06282.1 - 4.7e-174 568.7 97.8 5.2e-33 113.4 7.6 6.8 1 1 6 7 7 7 7 Mycoplasma protein of unknown function, DUF285 F-box_4 PF15966.5 OEU06282.1 - 0.0052 16.7 16.4 21 5.0 0.1 8.6 2 2 9 12 12 12 2 F-box bPH_4 PF06713.11 OEU06282.1 - 0.07 13.2 0.0 5.2 7.2 0.0 3.5 3 0 0 3 3 3 0 Bacterial PH domain PNRC PF15365.6 OEU06282.1 - 0.62 10.0 9.5 58 3.7 0.2 4.8 4 0 0 4 4 4 0 Proline-rich nuclear receptor coactivator motif Rick_17kDa_Anti PF05433.15 OEU06283.1 - 0.0031 17.3 0.5 0.0031 17.3 0.5 4.5 3 2 1 4 4 4 1 Glycine zipper 2TM domain DDE_3 PF13358.6 OEU06285.1 - 0.05 13.4 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 DDE superfamily endonuclease Itfg2 PF15907.5 OEU06286.1 - 0.25 10.4 3.8 1.6 7.7 0.1 2.1 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 MGC-24 PF05283.11 OEU06286.1 - 0.92 10.0 3.9 0.9 10.0 0.5 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GCD14 PF08704.10 OEU06286.1 - 3.9 7.1 6.2 1 9.0 0.5 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Pkinase PF00069.25 OEU06287.1 - 1.9e-37 129.1 0.0 2.1e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU06287.1 - 1.2e-16 60.8 0.0 1.3e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU06287.1 - 6.1e-05 22.5 1.8 8.3e-05 22.0 1.8 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU06287.1 - 0.0024 16.7 0.2 0.003 16.4 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OEU06287.1 - 0.0037 16.9 1.0 0.006 16.2 1.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OEU06287.1 - 0.11 12.4 0.5 0.15 12.0 0.5 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PBP1_TM PF14812.6 OEU06288.1 - 0.0017 18.6 4.3 0.0017 18.6 4.3 3.3 2 1 1 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3464 PF11947.8 OEU06288.1 - 1.4 8.6 10.1 0.76 9.5 0.1 3.5 3 1 0 3 3 3 0 Photosynthesis affected mutant 68 Orf78 PF06024.12 OEU06288.1 - 3.5 8.0 0.0 3.5 8.0 0.0 3.8 4 1 0 4 4 4 0 Orf78 (ac78) SID-1_RNA_chan PF13965.6 OEU06288.1 - 4.2 5.7 5.4 1.4 7.2 1.1 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF5315 PF17242.2 OEU06289.1 - 0.11 12.4 2.0 31 4.5 0.0 3.4 4 0 0 4 4 4 0 Disordered region of unknown function (DUF5315) BRX_N PF13713.6 OEU06289.1 - 0.13 12.1 3.0 55 3.7 0.1 3.3 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain DUF2749 PF10907.8 OEU06289.1 - 0.2 11.8 2.5 55 4.0 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2749) Imm25 PF15564.6 OEU06290.1 - 0.051 13.5 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 25 DUF2615 PF11027.8 OEU06291.1 - 0.00025 21.1 0.1 0.79 9.9 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2615) Orf78 PF06024.12 OEU06291.1 - 0.0013 19.0 0.8 0.0013 19.0 0.8 1.6 2 0 0 2 2 1 1 Orf78 (ac78) Comm PF15957.5 OEU06291.1 - 0.0027 18.0 5.6 0.63 10.4 0.0 2.2 2 0 0 2 2 2 2 Commissureless SARAF PF06682.12 OEU06291.1 - 0.0067 16.1 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Cadherin_C_2 PF16492.5 OEU06291.1 - 0.0099 16.6 0.0 2.1 9.1 0.0 2.3 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal LRRC37AB_C PF14914.6 OEU06291.1 - 0.018 15.0 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CD34_antigen PF06365.12 OEU06291.1 - 0.024 14.2 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family MSP1a PF11670.8 OEU06291.1 - 0.045 13.0 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) SafA PF17073.5 OEU06291.1 - 0.047 13.7 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Two-component-system connector protein Shisa PF13908.6 OEU06291.1 - 0.048 13.9 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 OEU06291.1 - 0.058 13.2 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2417 PF10329.9 OEU06291.1 - 0.08 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Plasmodium_Vir PF05795.11 OEU06291.1 - 0.084 12.3 5.7 0.046 13.1 3.7 1.5 1 1 0 2 2 2 0 Plasmodium vivax Vir protein WBP-1 PF11669.8 OEU06291.1 - 0.11 13.1 0.0 3.1 8.5 0.0 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 Ion_trans PF00520.31 OEU06291.1 - 0.13 11.5 4.7 0.17 11.1 4.7 1.2 1 0 0 1 1 1 0 Ion transport protein DUF1189 PF06691.11 OEU06291.1 - 5.1 6.6 7.4 2.8 7.5 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) Sigma_reg_N PF13800.6 OEU06291.1 - 7.2 7.0 6.4 25 5.3 0.7 2.4 2 1 0 2 2 2 0 Sigma factor regulator N-terminal RusA PF05866.11 OEU06292.1 - 1.2e-08 35.6 0.2 1.2e-08 35.6 0.2 1.8 2 0 0 2 2 2 1 Endodeoxyribonuclease RusA DUF4556 PF15094.6 OEU06292.1 - 0.095 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Nse4_C PF08743.10 OEU06292.1 - 1.3 9.3 4.8 0.58 10.5 0.2 2.5 2 1 0 3 3 3 0 Nse4 C-terminal Lectin_N PF03954.14 OEU06293.1 - 0.002 17.9 0.8 1.6 8.4 0.1 2.7 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain SIT PF15330.6 OEU06293.1 - 0.0058 17.1 2.4 1.6 9.2 0.0 3.6 3 1 0 3 3 3 2 SHP2-interacting transmembrane adaptor protein, SIT Chordopox_A13L PF05961.11 OEU06293.1 - 0.036 14.3 0.1 0.34 11.2 0.1 2.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Zip PF02535.22 OEU06293.1 - 0.13 11.4 9.4 0.2 10.8 0.0 3.0 4 0 0 4 4 4 0 ZIP Zinc transporter ACP53EA PF06313.11 OEU06293.1 - 0.19 12.0 1.3 0.45 10.7 0.2 2.2 2 0 0 2 2 2 0 Drosophila ACP53EA protein RIFIN PF02009.16 OEU06293.1 - 5.4 6.8 9.3 1.1 9.1 0.2 3.5 4 0 0 4 4 4 0 Rifin Rax2 PF12768.7 OEU06294.1 - 0.035 13.6 4.6 0.093 12.2 0.4 2.8 2 1 0 3 3 3 0 Cortical protein marker for cell polarity Band_3_cyto PF07565.13 OEU06294.1 - 0.16 11.7 6.2 0.018 14.9 1.3 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CAP_N PF01213.19 OEU06297.1 - 0.082 12.4 0.6 0.085 12.3 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Androgen_recep PF02166.16 OEU06297.1 - 0.082 11.7 0.5 0.081 11.8 0.5 1.1 1 0 0 1 1 1 0 Androgen receptor HMG_box_2 PF09011.10 OEU06299.1 - 1.7e-08 34.9 2.7 1.7e-08 34.9 2.7 2.3 2 1 1 3 3 3 1 HMG-box domain HMG_box PF00505.19 OEU06299.1 - 2.2e-07 31.2 4.9 2.2e-07 31.2 4.9 2.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.6 OEU06299.1 - 0.0033 17.4 3.6 0.0043 17.0 3.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box 5 E1-E2_ATPase PF00122.20 OEU06300.1 - 8.3e-06 25.4 0.1 0.0056 16.2 0.0 3.2 3 0 0 3 3 3 2 E1-E2 ATPase DUF202 PF02656.15 OEU06300.1 - 0.036 14.5 1.8 0.19 12.2 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ERM PF00769.19 OEU06302.1 - 0.0055 16.5 20.4 0.0055 16.5 20.4 6.7 1 1 4 5 5 5 1 Ezrin/radixin/moesin family DUF3800 PF12686.7 OEU06302.1 - 0.028 15.1 0.1 5.1 7.7 0.1 4.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF3446 PF11928.8 OEU06302.1 - 0.058 13.7 5.8 0.23 11.8 5.8 2.0 1 0 0 1 1 1 0 Early growth response N-terminal domain EF-hand_7 PF13499.6 OEU06303.1 - 0.00027 21.3 1.7 0.093 13.2 0.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OEU06303.1 - 0.00091 19.0 1.0 0.2 11.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OEU06303.1 - 0.033 13.7 1.6 1.1 8.9 0.0 3.4 3 0 0 3 3 3 0 EF hand HA PF03457.14 OEU06304.1 - 1.1e-33 115.3 3.9 3.6e-17 62.5 0.3 2.0 2 0 0 2 2 2 2 Helicase associated domain ATP-synt_E_2 PF08112.11 OEU06304.1 - 7.9e-05 22.9 1.7 0.044 14.1 0.1 2.3 2 0 0 2 2 2 2 ATP synthase epsilon subunit WHEP-TRS PF00458.20 OEU06304.1 - 0.015 15.4 0.8 5 7.4 0.0 2.3 2 0 0 2 2 2 0 WHEP-TRS domain Bystin PF05291.11 OEU06304.1 - 0.082 12.2 6.4 0.12 11.7 0.7 2.1 1 1 1 2 2 2 0 Bystin DDE_Tnp_1_7 PF13843.6 OEU06306.1 - 3.8e-17 62.6 0.2 8.9e-17 61.4 0.2 1.6 1 1 0 1 1 1 1 Transposase IS4 SelP_N PF04592.14 OEU06307.1 - 0.014 14.8 6.6 0.026 13.9 6.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ELH PF02323.15 OEU06308.1 - 0.016 14.6 4.8 0.02 14.3 4.8 1.1 1 0 0 1 1 1 0 Egg-laying hormone precursor NOA36 PF06524.12 OEU06308.1 - 0.17 11.2 7.7 0.21 10.9 7.7 1.1 1 0 0 1 1 1 0 NOA36 protein CCDC32 PF14989.6 OEU06309.1 - 0.00085 19.3 0.3 0.0017 18.4 0.3 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing 32 P5-ATPase PF12409.8 OEU06309.1 - 0.018 15.2 0.5 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter Pterin_4a PF01329.19 OEU06311.1 - 4.7e-07 29.9 2.9 2.5e-06 27.6 0.9 2.3 2 1 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Wzt_C PF14524.6 OEU06314.1 - 0.048 13.7 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain Ribosomal_L25p PF01386.19 OEU06315.1 - 1.3e-09 38.5 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 OEU06315.1 - 4.3e-06 27.0 0.0 8.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain GCV_H PF01597.19 OEU06318.1 - 5.7e-44 148.9 0.0 6.8e-44 148.7 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OEU06318.1 - 9.8e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 OEU06318.1 - 0.00016 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 OEU06318.1 - 0.031 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Glyco_transf_92 PF01697.27 OEU06319.1 - 5.9e-10 39.2 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 92 SR-25 PF10500.9 OEU06322.1 - 1.5 8.4 24.4 0.028 14.0 16.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Iron_traffic PF04362.14 OEU06323.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking AMP-binding PF00501.28 OEU06324.1 - 3.4e-43 147.8 0.0 5.3e-43 147.2 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OEU06324.1 - 2.6e-16 59.3 1.4 6.3e-16 58.0 1.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF575 PF04746.12 OEU06326.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF575) ATP-synt PF00231.19 OEU06327.1 - 0.03 14.0 1.7 3.2 7.4 0.5 2.0 1 1 1 2 2 2 0 ATP synthase Syncollin PF15138.6 OEU06327.1 - 0.035 14.3 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Syncollin RGS PF00615.19 OEU06328.1 - 0.15 12.4 2.3 0.32 11.3 2.2 1.8 1 1 0 1 1 1 0 Regulator of G protein signaling domain DFF-C PF09033.10 OEU06328.1 - 0.5 10.2 3.9 0.15 12.0 1.0 1.6 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain FAD_binding_1 PF00667.20 OEU06330.1 - 0.044 13.3 0.2 0.07 12.7 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain Destabilase PF05497.12 OEU06331.1 - 0.12 12.7 0.2 0.15 12.4 0.2 1.2 1 0 0 1 1 1 0 Destabilase BKACE PF05853.12 OEU06332.1 - 0.038 13.3 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Ank_2 PF12796.7 OEU06334.1 - 0.011 16.3 0.3 0.55 10.9 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ferlin_C PF16165.5 OEU06334.1 - 8.2 6.4 9.6 1.4 8.9 5.2 2.0 2 0 0 2 2 2 0 Ferlin C-terminus PTPRCAP PF15713.5 OEU06334.1 - 8.3 6.7 9.9 5.9 7.2 4.7 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated UCR_Fe-S_N PF10399.9 OEU06335.1 - 0.057 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal zf-RVT PF13966.6 OEU06336.1 - 0.00037 21.1 4.1 0.0014 19.3 4.1 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase SelK_SelG PF10961.8 OEU06336.1 - 5.7 7.6 6.7 1.9e+02 2.7 7.5 3.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG TERB2 PF15101.6 OEU06337.1 - 0.0036 17.4 10.6 0.0049 17.0 10.6 1.3 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Tho2 PF11262.8 OEU06337.1 - 0.012 14.9 6.1 0.015 14.5 6.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NinG PF05766.12 OEU06337.1 - 0.012 15.6 9.7 0.019 14.9 9.7 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein CENP-B_dimeris PF09026.10 OEU06337.1 - 0.012 15.9 7.1 0.012 15.9 7.1 2.5 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Presenilin PF01080.17 OEU06337.1 - 0.037 12.8 7.8 0.042 12.6 7.8 1.1 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 OEU06337.1 - 0.047 12.4 18.3 0.079 11.6 18.3 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Band_3_cyto PF07565.13 OEU06337.1 - 0.051 13.4 2.8 0.056 13.2 2.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SDA1 PF05285.12 OEU06337.1 - 0.065 12.6 14.3 0.091 12.2 14.3 1.2 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 OEU06337.1 - 0.11 12.3 3.3 0.13 12.0 3.3 1.3 1 0 0 1 1 1 0 Connexin DUF4175 PF13779.6 OEU06337.1 - 0.12 10.3 17.0 0.13 10.2 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EIIBC-GUT_N PF03612.14 OEU06337.1 - 0.15 11.8 4.7 0.23 11.2 4.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_23 PF13476.6 OEU06337.1 - 0.16 12.5 14.5 0.25 11.8 14.5 1.4 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.6 OEU06337.1 - 0.21 11.4 10.8 0.12 12.2 8.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Spt5_N PF11942.8 OEU06337.1 - 0.24 12.4 18.8 0.45 11.5 18.8 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PepSY_TM PF03929.16 OEU06337.1 - 0.35 10.5 1.1 0.4 10.3 1.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Neur_chan_memb PF02932.16 OEU06337.1 - 0.36 10.8 4.5 0.42 10.6 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 OEU06337.1 - 0.4 10.0 8.1 0.45 9.8 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CSG2 PF16965.5 OEU06337.1 - 0.41 9.5 4.1 0.54 9.1 4.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator G0-G1_switch_2 PF15103.6 OEU06337.1 - 0.73 10.3 5.1 1.3 9.5 5.1 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Folate_carrier PF01770.18 OEU06337.1 - 0.77 8.4 2.1 0.9 8.2 2.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier CDC45 PF02724.14 OEU06337.1 - 0.84 7.8 15.8 1.1 7.4 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 OEU06337.1 - 0.87 8.6 3.8 1.1 8.3 3.8 1.1 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 OEU06337.1 - 0.91 9.4 3.1 1.2 9.0 3.1 1.2 1 0 0 1 1 1 0 N-glycosylation protein ALMT PF11744.8 OEU06337.1 - 1.1 8.0 5.7 1.2 7.9 5.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Slu7 PF11708.8 OEU06337.1 - 1.1 8.9 18.5 1.3 8.7 9.6 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor MDM10 PF12519.8 OEU06337.1 - 1.7 7.4 6.6 2.2 7.0 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SprA-related PF12118.8 OEU06337.1 - 1.8 7.6 18.5 2.6 7.1 18.5 1.3 1 0 0 1 1 1 0 SprA-related family Peptidase_S49_N PF08496.10 OEU06337.1 - 2.3 8.2 10.7 5.6 7.0 9.5 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ureide_permease PF07168.11 OEU06337.1 - 4.3 6.0 3.8 6.2 5.5 3.8 1.2 1 0 0 1 1 1 0 Ureide permease M_domain PF12938.7 OEU06337.1 - 4.7 6.9 33.0 6.3 6.5 33.0 1.2 1 0 0 1 1 1 0 M domain of GW182 Afi1 PF07792.12 OEU06337.1 - 4.9 7.6 18.4 8.4 6.9 9.1 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EMC3_TMCO1 PF01956.16 OEU06337.1 - 5.3 6.7 9.3 6.8 6.4 9.3 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Methyltransf_4 PF02390.17 OEU06338.1 - 2e-10 40.4 1.4 1.4e-08 34.4 0.3 3.3 2 2 0 2 2 2 2 Putative methyltransferase WD40 PF00400.32 OEU06339.1 - 0.032 15.1 2.8 0.59 11.1 0.3 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Retrotran_gag_2 PF14223.6 OEU06340.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Yae1_N PF09811.9 OEU06341.1 - 4.5e-11 42.3 62.2 0.36 10.6 2.9 13.0 2 2 7 9 9 9 8 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU06341.1 - 0.032 14.3 0.0 15 5.7 0.0 3.6 2 1 1 4 4 4 0 Outer membrane protein beta-barrel domain PagL PF09411.10 OEU06341.1 - 0.23 11.6 1.1 1.6e+02 2.4 0.0 4.0 2 1 2 4 4 4 0 Lipid A 3-O-deacylase (PagL) MspA PF09203.11 OEU06341.1 - 0.61 9.9 3.8 87 2.9 3.8 3.5 1 1 0 1 1 1 0 MspA Sulfotransfer_2 PF03567.14 OEU06342.1 - 1.5e-09 38.1 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4207 PF13904.6 OEU06343.1 - 0.54 9.9 27.8 0.88 9.2 27.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) U1snRNP70_N PF12220.8 OEU06343.1 - 3 8.6 18.1 0.039 14.6 6.4 2.5 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4637 PF15470.6 OEU06343.1 - 3.4 7.4 10.5 7.4 6.3 10.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) DTHCT PF08070.11 OEU06344.1 - 0.15 12.8 10.3 0.17 12.6 10.3 1.1 1 0 0 1 1 1 0 DTHCT (NUC029) region Pinin_SDK_N PF04697.13 OEU06344.1 - 0.27 11.9 6.3 1.2 9.8 6.3 1.9 1 1 0 1 1 1 0 pinin/SDK conserved region DUF3246 PF11596.8 OEU06344.1 - 1.2 8.5 15.1 2.4 7.5 15.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) S-antigen PF05756.11 OEU06344.1 - 4.3 7.8 9.0 8.4 6.8 1.2 2.1 2 0 0 2 2 2 0 S-antigen protein IMUP PF15761.5 OEU06345.1 - 0.055 14.2 1.0 0.055 14.2 1.0 3.4 3 0 0 3 3 3 0 Immortalisation up-regulated protein FG-GAP_2 PF14312.6 OEU06347.1 - 2.1e-19 69.5 23.9 0.0025 18.0 0.3 7.7 7 0 0 7 7 7 7 FG-GAP repeat DUF5122 PF17164.4 OEU06347.1 - 0.39 11.0 5.2 20 5.6 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller DUF3592 PF12158.8 OEU06349.1 - 0.048 13.7 1.3 0.064 13.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) CBM_25 PF03423.13 OEU06349.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Dsh_C PF12316.8 OEU06349.1 - 5.2 7.4 12.4 4.4 7.6 10.9 1.6 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Fijivirus_P9-2 PF06837.11 OEU06350.1 - 0.088 12.2 0.1 0.088 12.2 0.1 2.1 2 0 0 2 2 2 0 Fijivirus P9-2 protein TFB6 PF17110.5 OEU06350.1 - 0.34 10.7 8.8 0.072 12.8 0.7 2.7 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH GEN1_C PF18380.1 OEU06350.1 - 3 8.8 7.5 3.7 8.5 0.2 2.7 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain F-box PF00646.33 OEU06351.1 - 1.4e-05 24.9 0.0 4.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OEU06351.1 - 2.5e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OEU06351.1 - 0.0028 17.5 2.9 0.0062 16.4 0.1 2.7 2 1 1 3 3 3 1 F-box Trypan_PARP PF05887.11 OEU06353.1 - 0.18 11.8 5.0 0.95 9.4 2.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PAP2 PF01569.21 OEU06356.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 PAP2 superfamily ABC2_membrane_3 PF12698.7 OEU06356.1 - 0.17 11.0 9.1 0.012 14.8 2.8 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Serinc PF03348.15 OEU06356.1 - 0.45 9.4 6.9 14 4.5 6.9 2.2 1 1 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.15 OEU06356.1 - 2.2 8.9 8.2 0.7 10.5 3.1 2.5 2 1 0 2 2 2 0 Ctr copper transporter family Miga PF10265.9 OEU06356.1 - 5.5 5.8 13.1 9.3 5.1 13.1 1.4 1 1 0 1 1 1 0 Mitoguardin Exo_endo_phos PF03372.23 OEU06357.1 - 3.6e-08 33.2 0.2 1.2e-07 31.5 0.3 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RNF111_N PF15303.6 OEU06358.1 - 0.026 14.3 0.5 0.04 13.7 0.5 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Dirigent PF03018.14 OEU06359.1 - 0.024 14.5 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Dirigent-like protein Fasciclin PF02469.22 OEU06360.1 - 1e-68 229.5 0.0 7.2e-34 116.8 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain FLgD_tudor PF13861.6 OEU06360.1 - 0.0045 17.2 0.0 0.12 12.7 0.0 3.0 1 1 0 1 1 1 1 FlgD Tudor-like domain HTH_Tnp_IS1 PF12759.7 OEU06361.1 - 0.0038 16.8 10.2 2.1 8.0 0.0 7.9 9 0 0 9 9 9 3 InsA C-terminal domain PA-IIL PF07472.11 OEU06361.1 - 0.26 11.6 3.3 29 5.0 0.3 3.6 3 0 0 3 3 3 0 Fucose-binding lectin II (PA-IIL) Orf78 PF06024.12 OEU06363.1 - 0.2 12.0 0.2 0.2 12.0 0.2 4.0 4 1 1 5 5 5 0 Orf78 (ac78) DUF1125 PF06563.11 OEU06365.1 - 0.031 14.2 0.2 0.058 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1125) DUF4834 PF16118.5 OEU06366.1 - 0.0097 16.8 0.0 0.075 14.0 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) CCSMST1 PF15013.6 OEU06366.1 - 0.071 13.3 0.6 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 CCSMST1 family BTB_2 PF02214.22 OEU06368.1 - 1.5e-09 38.1 0.1 1.7e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain Hamartin PF04388.12 OEU06368.1 - 0.0034 16.2 12.7 0.0039 15.9 12.7 1.1 1 0 0 1 1 1 1 Hamartin protein RPA43_OB PF17875.1 OEU06368.1 - 0.087 13.4 2.7 0.19 12.3 2.7 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I NOA36 PF06524.12 OEU06368.1 - 0.35 10.2 6.6 0.68 9.2 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein SelP_N PF04592.14 OEU06369.1 - 0.043 13.2 9.1 0.061 12.7 9.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.16 OEU06369.1 - 0.37 10.1 4.0 0.44 9.9 4.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Anticodon_1 PF08264.13 OEU06370.1 - 0.00062 19.8 0.1 0.42 10.6 0.0 3.0 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA Dirigent PF03018.14 OEU06371.1 - 0.015 15.1 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Dirigent-like protein YojJ PF10372.9 OEU06372.1 - 0.0007 19.6 1.6 0.4 10.8 0.5 2.5 2 0 0 2 2 2 2 Bacterial membrane-spanning protein N-terminus Nairovirus_M PF07948.11 OEU06372.1 - 0.008 14.5 0.1 0.0098 14.2 0.1 1.1 1 0 0 1 1 1 1 Nairovirus M polyprotein-like Nipped-B_C PF12830.7 OEU06372.1 - 0.047 13.6 0.4 0.066 13.1 0.4 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus HIP1_clath_bdg PF16515.5 OEU06372.1 - 0.09 13.4 3.1 0.43 11.2 1.5 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 OEU06372.1 - 1 9.4 5.1 0.95 9.5 2.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4148 PF13663.6 OEU06373.1 - 0.026 14.7 2.2 0.074 13.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) CHASE3 PF05227.13 OEU06374.1 - 0.045 13.7 4.8 1 9.3 0.0 2.5 2 0 0 2 2 2 0 CHASE3 domain Clr2 PF10383.9 OEU06374.1 - 0.061 14.1 1.5 0.11 13.2 1.5 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DZR PF12773.7 OEU06374.1 - 0.12 12.4 1.8 0.28 11.2 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU06374.1 - 0.13 12.0 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S2 PF00318.20 OEU06374.1 - 2.4 7.3 6.8 0.12 11.5 0.4 2.2 3 0 0 3 3 3 0 Ribosomal protein S2 PFEMP PF03011.15 OEU06374.1 - 6.1 7.5 10.0 0.1 13.2 1.7 2.2 3 0 0 3 3 3 0 PFEMP DBL domain Y_phosphatase3 PF13350.6 OEU06375.1 - 1.8e-17 64.1 1.5 2.3e-16 60.5 1.5 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OEU06375.1 - 0.00089 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 OEU06375.1 - 0.0023 17.5 0.1 0.0051 16.4 0.1 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 OEU06375.1 - 0.0068 15.4 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PTase_Orf2 PF11468.8 OEU06377.1 - 0.094 12.1 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 Dirigent PF03018.14 OEU06378.1 - 0.014 15.2 0.2 0.03 14.1 0.2 1.5 1 0 0 1 1 1 0 Dirigent-like protein Peptidase_C14 PF00656.22 OEU06379.1 - 1.4e-54 185.6 0.8 2.3e-54 185.0 0.8 1.2 1 0 0 1 1 1 1 Caspase domain CRR7 PF12095.8 OEU06379.1 - 0.16 12.4 0.4 5.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF2704 PF10866.8 OEU06379.1 - 0.17 11.7 2.2 0.17 11.8 0.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2704) Tfb4 PF03850.14 OEU06379.1 - 0.2 11.1 2.0 0.24 10.9 0.6 1.7 2 0 0 2 2 2 0 Transcription factor Tfb4 PT PF04886.12 OEU06380.1 - 7e-12 44.7 50.0 27 4.4 50.0 3.0 1 1 0 1 1 1 1 PT repeat Glycoprotein_G PF00802.19 OEU06380.1 - 2.5 7.4 8.1 2.6 7.3 8.1 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Yae1_N PF09811.9 OEU06384.1 - 2.4e-15 55.9 52.9 0.045 13.5 0.4 14.8 3 3 11 14 14 14 12 Essential protein Yae1, N terminal Raftlin PF15250.6 OEU06386.1 - 0.11 11.2 16.2 0.14 10.9 16.2 1.1 1 0 0 1 1 1 0 Raftlin Ac76 PF05814.11 OEU06386.1 - 2 8.5 5.9 4.3 7.4 5.9 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) SR-25 PF10500.9 OEU06386.1 - 2.5 7.6 36.3 3.9 7.0 36.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF936 PF06075.12 OEU06386.1 - 3.4 6.5 19.2 3.5 6.4 19.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF1387 PF07139.11 OEU06386.1 - 5.5 6.6 28.2 6.6 6.4 28.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIF_alpha PF05793.12 OEU06386.1 - 8.4 4.9 34.4 10 4.5 34.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLC12 PF03522.15 OEU06386.1 - 9.4 5.1 21.4 13 4.7 21.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 zf-MYND PF01753.18 OEU06389.1 - 3.7e-05 23.7 16.2 0.00033 20.7 12.9 2.8 1 1 1 2 2 2 2 MYND finger DUF1908 PF08926.11 OEU06392.1 - 0.00087 18.5 2.3 0.00087 18.5 2.3 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1908) SET PF00856.28 OEU06392.1 - 0.0023 18.3 2.6 0.0023 18.3 2.6 3.6 3 2 0 3 3 3 1 SET domain Pinin_SDK_N PF04697.13 OEU06393.1 - 0.024 15.3 1.0 0.046 14.4 1.0 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region GREB1 PF15782.5 OEU06394.1 - 7.7 3.5 18.0 9 3.3 18.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4050 PF13259.6 OEU06395.1 - 1.2e-05 25.7 7.6 1.2e-05 25.7 7.6 3.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4050) DUF3494 PF11999.8 OEU06396.1 - 1.2e-59 201.5 17.6 1.4e-59 201.2 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Spond_N PF06468.13 OEU06397.1 - 9.1e-32 110.7 0.7 1.6e-31 109.9 0.7 1.3 1 0 0 1 1 1 1 Spondin_N DUF3124 PF11322.8 OEU06397.1 - 0.022 14.9 1.0 2.3 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3124) PepSY_2 PF13670.6 OEU06397.1 - 0.037 14.0 0.3 0.79 9.8 0.1 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain UPF0370 PF13980.6 OEU06397.1 - 0.071 13.1 4.7 0.12 12.4 2.9 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0370) SH3_2 PF07653.17 OEU06398.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Atrophin-1 PF03154.15 OEU06398.1 - 2.2 6.5 25.8 0.01 14.2 17.1 1.5 2 0 0 2 2 2 0 Atrophin-1 family BTB_2 PF02214.22 OEU06399.1 - 0.13 12.6 0.4 0.53 10.7 0.4 2.1 1 1 0 1 1 1 0 BTB/POZ domain FHIPEP PF00771.20 OEU06399.1 - 5 5.5 5.3 17 3.7 5.3 1.8 1 0 0 1 1 1 0 FHIPEP family UNC-79 PF14776.6 OEU06400.1 - 0.017 13.9 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 VitD-bind_III PF09164.10 OEU06400.1 - 0.078 13.0 0.7 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III PGG PF13962.6 OEU06402.1 - 0.1 12.4 3.2 0.62 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DnaJ PF00226.31 OEU06403.1 - 8e-16 57.9 0.5 2.1e-15 56.6 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain WW PF00397.26 OEU06403.1 - 2.9e-08 33.6 2.1 1e-07 31.9 2.1 2.0 1 0 0 1 1 1 1 WW domain CD225 PF04505.12 OEU06403.1 - 4.2e-06 26.8 0.0 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 2 Interferon-induced transmembrane protein Connexin PF00029.19 OEU06403.1 - 0.0073 16.1 2.9 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Connexin UPF0242 PF06785.11 OEU06403.1 - 0.92 9.6 0.0 0.92 9.6 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3464 PF11947.8 OEU06403.1 - 2.8 7.7 7.5 1.4e+02 2.2 0.0 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 EIIBC-GUT_N PF03612.14 OEU06403.1 - 3.5 7.3 6.8 24 4.6 0.0 2.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 OEU06403.1 - 8.3 5.3 7.9 21 4.0 0.0 2.4 2 0 0 2 2 2 0 CLN3 protein HA PF03457.14 OEU06404.1 - 1.8e-56 188.4 19.6 4.2e-19 68.7 2.0 4.1 4 0 0 4 4 4 4 Helicase associated domain Ribosomal_L7Ae PF01248.26 OEU06404.1 - 0.037 13.8 0.0 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CASP_C PF08172.12 OEU06404.1 - 0.099 12.0 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal Kelch_1 PF01344.25 OEU06404.1 - 1.2 8.8 2.9 7.7 6.2 0.0 3.2 4 0 0 4 4 4 0 Kelch motif AAA PF00004.29 OEU06406.1 - 6.4e-26 91.3 0.0 7.2e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU06406.1 - 0.00012 22.0 0.1 0.00045 20.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OEU06406.1 - 0.00021 21.8 0.0 0.00027 21.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OEU06406.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OEU06406.1 - 0.0042 17.1 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU06406.1 - 0.0047 17.1 0.0 0.0062 16.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OEU06406.1 - 0.0068 16.5 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OEU06406.1 - 0.0084 16.4 1.3 1.2 9.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OEU06406.1 - 0.0088 15.8 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OEU06406.1 - 0.0093 15.6 0.3 0.53 9.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU06406.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 OEU06406.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OEU06406.1 - 0.052 13.4 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OEU06406.1 - 0.058 13.3 0.0 0.085 12.8 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 OEU06406.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase SKI PF01202.22 OEU06406.1 - 0.062 13.4 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Cytidylate_kin2 PF13189.6 OEU06406.1 - 0.07 13.3 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_24 PF13479.6 OEU06406.1 - 0.11 12.2 0.1 0.31 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU06406.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.6 2 0 0 2 2 2 0 RNA helicase Fasciclin PF02469.22 OEU06408.1 - 0.02 15.1 0.5 0.02 15.1 0.5 1.6 2 0 0 2 2 2 0 Fasciclin domain OxoDH_E1alpha_N PF12573.8 OEU06410.1 - 0.12 12.1 0.2 0.29 10.9 0.2 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Phage_GPL PF05926.11 OEU06410.1 - 0.44 10.5 4.7 2 8.4 1.1 2.8 3 0 0 3 3 3 0 Phage head completion protein (GPL) Doppel PF11466.8 OEU06411.1 - 0.62 9.8 2.7 0.77 9.5 1.0 1.9 2 0 0 2 2 2 0 Prion-like protein Doppel DUF2079 PF09852.9 OEU06412.1 - 0.029 13.3 2.2 4 6.2 0.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) Mem_trans PF03547.18 OEU06413.1 - 5.6e-08 31.6 19.2 2.1e-06 26.4 6.4 3.1 2 1 0 2 2 2 2 Membrane transport protein PT PF04886.12 OEU06414.1 - 1.4e-10 40.5 79.9 3.1e-05 23.4 10.8 7.4 3 3 2 5 5 5 4 PT repeat Epimerase PF01370.21 OEU06415.1 - 1.3e-06 28.1 0.0 3e-05 23.6 0.0 2.1 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU06415.1 - 2.8e-06 27.0 0.0 4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU06415.1 - 0.00015 20.9 0.0 0.0073 15.3 0.0 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OEU06415.1 - 0.00041 19.6 0.0 0.047 12.9 0.0 2.7 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OEU06415.1 - 0.0038 17.2 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OEU06415.1 - 0.042 13.0 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2761 PF10959.8 OEU06415.1 - 0.051 13.6 0.4 1.1 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2761) NmrA PF05368.13 OEU06415.1 - 0.051 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Methyltransf_25 PF13649.6 OEU06418.1 - 6.4e-05 23.6 0.0 0.00027 21.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU06418.1 - 1.4 9.7 0.0 1.4 9.7 0.0 5.8 5 1 0 5 5 5 0 Methyltransferase domain cobW PF02492.19 OEU06419.1 - 2.3e-23 82.7 6.9 9.7e-18 64.4 0.9 3.2 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU06419.1 - 9.4e-09 35.1 0.0 0.00012 21.9 0.0 3.2 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OEU06419.1 - 0.0008 19.3 0.6 0.14 12.0 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 OEU06419.1 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 OEU06419.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 OEU06419.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OEU06419.1 - 0.03 14.6 0.0 0.093 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OEU06419.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU06419.1 - 0.17 12.2 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain U1snRNP70_N PF12220.8 OEU06419.1 - 0.56 10.9 6.5 3.9 8.2 0.6 2.9 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ank_4 PF13637.6 OEU06421.1 - 0.00081 19.9 0.0 0.34 11.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU06421.1 - 0.0022 18.3 0.0 0.054 13.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU06421.1 - 0.031 14.9 0.0 0.11 13.1 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) TFIIA PF03153.13 OEU06421.1 - 1.6 8.6 24.1 2.3 8.1 24.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cauli_AT PF03233.13 OEU06422.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Aphid transmission protein Mucin PF01456.17 OEU06424.1 - 0.42 10.6 15.3 0.63 10.0 15.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Baculo_p24 PF05073.12 OEU06424.1 - 0.7 9.6 4.3 0.26 11.0 0.5 1.9 2 0 0 2 2 2 0 Baculovirus P24 capsid protein SSP160 PF06933.11 OEU06424.1 - 4.2 5.4 13.7 6 4.9 13.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 OEU06424.1 - 7.2 6.6 12.2 16 5.5 12.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Fungus-induced PF10917.8 OEU06425.1 - 0.37 11.1 3.5 0.95 9.8 3.5 1.7 1 0 0 1 1 1 0 Fungus-induced protein NAM-associated PF14303.6 OEU06426.1 - 9.5e-05 23.2 0.6 0.00022 22.0 0.6 1.6 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Ank_2 PF12796.7 OEU06428.1 - 3.2e-11 43.7 0.7 6.6e-05 23.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU06428.1 - 3.3e-08 33.6 0.1 8.8e-05 22.7 0.0 4.5 2 1 2 4 4 4 1 Ankyrin repeats (many copies) DNA_pol_A_exo1 PF01612.20 OEU06428.1 - 7.1e-08 32.4 0.7 4.4e-06 26.5 0.0 3.1 3 0 0 3 3 3 1 3'-5' exonuclease Ank_4 PF13637.6 OEU06428.1 - 2.6e-07 31.0 0.0 1.4e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU06428.1 - 5.5e-05 23.2 0.0 0.043 14.4 0.0 4.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU06428.1 - 0.0055 17.1 0.0 0.061 13.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat DUF3683 PF12447.8 OEU06428.1 - 0.042 14.0 1.1 0.11 12.6 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) DUF2848 PF11010.8 OEU06428.1 - 0.048 13.3 1.9 0.049 13.2 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2848) TLD PF07534.16 OEU06429.1 - 8.2e-22 77.9 0.1 2.3e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 TLD Amino_oxidase PF01593.24 OEU06430.1 - 2e-12 47.2 0.0 8.9e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU06430.1 - 1.2e-09 38.3 0.1 3.3e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU06430.1 - 0.00024 20.4 0.1 0.0039 16.5 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU06430.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 OEU06430.1 - 0.00056 19.2 1.4 0.00099 18.4 0.0 2.0 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 OEU06430.1 - 0.002 17.8 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4263 PF14082.6 OEU06430.1 - 0.11 12.7 1.6 0.24 11.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) HI0933_like PF03486.14 OEU06430.1 - 0.15 10.7 0.1 14 4.2 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Ifi-6-16 PF06140.13 OEU06432.1 - 1.8e-17 63.0 35.8 3.5e-17 62.1 35.8 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family RicinB_lectin_2 PF14200.6 OEU06432.1 - 2.2e-05 25.1 1.5 0.061 14.1 0.4 3.3 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.13 OEU06432.1 - 0.00013 22.1 1.6 0.18 12.1 0.1 2.6 1 1 0 2 2 2 2 Fascin domain FGF PF00167.18 OEU06432.1 - 0.001 19.2 0.0 21 5.2 0.0 3.2 1 1 2 3 3 3 2 Fibroblast growth factor Sortilin-Vps10 PF15902.5 OEU06432.1 - 0.0019 17.1 1.6 0.0024 16.7 1.6 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, UPF0767 PF15990.5 OEU06432.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.4 1 0 0 1 1 1 0 UPF0767 family DUF5585 PF17823.1 OEU06432.1 - 4.8 6.0 9.9 6.5 5.6 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) RskA PF10099.9 OEU06433.1 - 0.96 9.7 0.0 0.96 9.7 0.0 9.0 2 2 2 4 4 4 0 Anti-sigma-K factor rskA Ank PF00023.30 OEU06434.1 - 0.00019 21.7 0.8 5.5 7.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OEU06434.1 - 0.003 17.8 1.8 42 4.6 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU06434.1 - 0.013 16.0 1.1 59 4.7 0.0 5.1 6 0 0 6 6 6 0 Ankyrin repeat MMR1 PF08505.10 OEU06435.1 - 0.0037 17.6 12.0 0.0037 17.6 12.0 2.2 2 0 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein RskA PF10099.9 OEU06435.1 - 0.015 15.6 0.7 0.061 13.6 0.8 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA EPL1 PF10513.9 OEU06435.1 - 0.043 14.2 13.0 0.055 13.9 8.0 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like YfhO PF09586.10 OEU06435.1 - 0.13 10.5 12.4 0.18 10.0 12.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Exonuc_VII_L PF02601.15 OEU06435.1 - 0.15 11.6 11.1 0.22 11.1 11.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 OEU06435.1 - 0.15 11.0 25.3 0.22 10.5 25.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GNAT_acetyltr_2 PF13718.6 OEU06435.1 - 0.22 10.9 7.2 0.37 10.2 6.4 1.7 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Spt20 PF12090.8 OEU06435.1 - 0.39 10.3 32.2 0.99 9.0 32.2 1.6 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 OEU06435.1 - 0.39 10.8 11.6 0.19 11.9 7.7 2.0 2 0 0 2 2 2 0 DDHD domain GBP_C PF02841.14 OEU06435.1 - 0.65 9.3 20.6 1.1 8.6 20.6 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Tim54 PF11711.8 OEU06435.1 - 1.6 7.4 11.4 2.8 6.6 11.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1764 PF08576.10 OEU06435.1 - 2.1 9.3 13.8 6.4 7.7 13.8 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_L6e PF01159.19 OEU06435.1 - 2.1 8.9 14.6 4.3 7.9 14.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L6e Connexin PF00029.19 OEU06435.1 - 3.1 7.5 8.0 5.2 6.7 8.0 1.3 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 OEU06435.1 - 6.3 7.1 21.5 16 5.8 21.5 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SET PF00856.28 OEU06436.1 - 1.5e-06 28.7 0.0 4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 SET domain Mcp5_PH PF12814.7 OEU06438.1 - 0.5 10.5 3.4 33 4.6 0.2 3.2 2 1 1 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PSI PF01437.25 OEU06438.1 - 1.5 9.4 25.4 0.96 10.0 2.4 3.4 2 1 1 3 3 3 0 Plexin repeat Sulfotransfer_3 PF13469.6 OEU06440.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family ABC_trans_N PF14510.6 OEU06441.1 - 0.1 13.2 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal DUF285 PF03382.14 OEU06442.1 - 3.1e-53 178.7 22.0 5.7e-28 97.1 6.1 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 PT PF04886.12 OEU06442.1 - 9.1e-05 21.9 16.3 0.00029 20.3 16.3 1.8 1 0 0 1 1 1 1 PT repeat DUF5527 PF17665.1 OEU06443.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) PAP_fibrillin PF04755.12 OEU06444.1 - 1.3e-05 25.3 0.1 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 2 PAP_fibrillin HSF_DNA-bind PF00447.17 OEU06445.1 - 4.2e-28 97.8 0.3 6.7e-28 97.2 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TBCC_N PF16752.5 OEU06445.1 - 0.056 13.9 1.9 0.075 13.5 0.1 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DnaJ_CXXCXGXG PF00684.19 OEU06446.1 - 3.2e-14 53.0 77.6 2.6e-05 24.5 7.3 7.2 2 2 7 9 9 8 7 DnaJ central domain zf-C3HC4_3 PF13920.6 OEU06446.1 - 1.7e-05 24.6 8.0 1.7e-05 24.6 8.0 6.9 3 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU06446.1 - 3e-05 24.2 9.1 3e-05 24.2 9.1 4.9 4 2 1 5 5 5 1 Ring finger domain Anti-TRAP PF15777.5 OEU06446.1 - 7.7e-05 22.6 1.7 7.7e-05 22.6 1.7 9.2 3 3 6 10 10 10 5 Tryptophan RNA-binding attenuator protein inhibitory protein zf-C3HC4_2 PF13923.6 OEU06446.1 - 0.00038 20.2 9.4 0.00038 20.2 9.4 5.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU06446.1 - 0.0069 16.2 10.4 0.0069 16.2 10.4 6.1 7 2 1 8 8 8 1 Zinc finger, C3HC4 type (RING finger) DUF932 PF06067.11 OEU06446.1 - 0.6 9.8 0.1 0.6 9.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF932) ABC_membrane PF00664.23 OEU06448.1 - 4.6e-52 177.3 28.3 6.5e-29 101.4 7.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU06448.1 - 4.9e-47 159.9 0.0 4.7e-27 95.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OEU06448.1 - 1.1e-10 41.4 4.8 0.00042 19.8 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU06448.1 - 1.5e-05 25.0 1.2 0.08 13.0 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 OEU06448.1 - 4.1e-05 23.6 1.3 0.49 10.2 0.0 3.9 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OEU06448.1 - 5.8e-05 23.5 0.0 0.31 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU06448.1 - 0.00021 21.0 3.2 0.12 12.2 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU06448.1 - 0.00049 20.0 2.6 0.066 13.1 1.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OEU06448.1 - 0.002 18.2 7.5 0.018 15.1 1.4 2.8 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.12 OEU06448.1 - 0.0027 17.0 0.2 0.36 10.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 OEU06448.1 - 0.0037 17.4 3.6 0.75 9.8 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain RNA_helicase PF00910.22 OEU06448.1 - 0.0057 17.0 0.3 1.3 9.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase T2SSE PF00437.20 OEU06448.1 - 0.0071 15.4 3.5 0.69 8.9 0.8 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein DEAD PF00270.29 OEU06448.1 - 0.0082 15.9 1.3 0.24 11.2 0.2 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 OEU06448.1 - 0.011 15.3 0.8 0.54 9.7 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 OEU06448.1 - 0.012 15.9 2.0 4.9 7.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OEU06448.1 - 0.014 15.6 0.1 8.4 6.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 OEU06448.1 - 0.017 14.7 0.8 0.52 9.9 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OEU06448.1 - 0.024 15.1 2.8 3.4 8.1 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OEU06448.1 - 0.031 14.7 0.0 11 6.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OEU06448.1 - 0.042 13.6 0.3 22 4.7 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OEU06448.1 - 0.043 13.7 0.2 0.92 9.4 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OEU06448.1 - 0.054 13.2 0.1 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0093 PF03653.13 OEU06448.1 - 0.099 12.9 4.4 0.22 11.7 4.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) NB-ARC PF00931.22 OEU06448.1 - 0.11 11.6 2.4 5.8 6.0 0.1 2.7 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 OEU06448.1 - 0.13 11.4 0.4 5.8 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 OEU06448.1 - 0.19 11.6 0.4 5.6 6.9 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_35 PF14516.6 OEU06448.1 - 0.2 10.5 0.0 0.44 9.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.18 OEU06448.1 - 0.41 10.0 3.5 11 5.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 OEU06448.1 - 0.46 9.7 2.1 2.8 7.1 0.0 2.3 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.6 OEU06448.1 - 0.59 9.8 3.7 3.4 7.3 0.2 2.4 3 0 0 3 3 2 0 AAA ATPase domain Glyco_tranf_2_4 PF13704.6 OEU06450.1 - 3.1e-10 40.4 0.5 8.9e-10 39.0 0.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 OEU06450.1 - 3e-08 33.7 2.5 6.1e-08 32.6 2.5 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Hexokinase_2 PF03727.16 OEU06451.1 - 0.028 13.8 0.2 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 Hexokinase Sigma70_ner PF04546.13 OEU06451.1 - 0.033 14.1 0.2 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Glyco_transf_8 PF01501.20 OEU06452.1 - 1.7e-07 31.0 2.1 4.6e-06 26.4 0.0 2.6 2 1 1 3 3 3 2 Glycosyl transferase family 8 TLD PF07534.16 OEU06453.1 - 1e-13 51.7 1.5 1.4e-13 51.2 0.2 1.8 2 0 0 2 2 2 1 TLD RAM PF15320.6 OEU06454.1 - 7.1 7.3 7.1 0.28 11.8 1.2 1.7 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Nuc_deoxyri_tr2 PF15891.5 OEU06457.1 - 7.2e-35 119.6 0.0 1.1e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like PT PF04886.12 OEU06458.1 - 4.6e-05 22.9 45.6 0.00025 20.5 16.0 12.8 5 3 4 9 9 9 6 PT repeat HATPase_c PF02518.26 OEU06459.1 - 2.9e-21 76.1 0.0 1.1e-20 74.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OEU06459.1 - 1.2e-07 31.9 0.0 4.7e-06 26.7 0.0 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OEU06459.1 - 9.7e-05 22.3 0.0 0.00034 20.6 0.0 2.0 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain LST1 PF05083.13 OEU06459.1 - 0.17 12.2 0.2 14 6.0 0.0 2.9 2 0 0 2 2 2 0 LST-1 protein DUF3772 PF12607.8 OEU06459.1 - 0.21 11.4 0.9 0.54 10.1 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) DUF3800 PF12686.7 OEU06461.1 - 0.06 14.0 0.2 0.11 13.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Bestrophin PF01062.21 OEU06462.1 - 2.1e-41 142.3 0.1 2.8e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Amidinotransf PF02274.17 OEU06463.1 - 6.8e-13 48.4 0.1 8.9e-12 44.7 0.2 2.0 2 0 0 2 2 2 1 Amidinotransferase Orn_DAP_Arg_deC PF00278.22 OEU06463.1 - 0.13 12.5 0.0 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Helicase_C_2 PF13307.6 OEU06464.1 - 4.7e-49 166.8 0.0 1.5e-48 165.2 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OEU06464.1 - 6.3e-34 117.1 0.7 1.3e-33 116.1 0.7 1.5 1 0 0 1 1 1 1 DEAD_2 Mito_fiss_reg PF05308.11 OEU06464.1 - 0.22 11.6 5.6 0.074 13.1 2.7 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator GFO_IDH_MocA PF01408.22 OEU06465.1 - 5.9e-10 40.0 0.0 1.4e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Kelch_4 PF13418.6 OEU06467.1 - 2.9e-30 104.0 5.2 2.6e-10 40.1 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 OEU06467.1 - 1.7e-28 98.0 3.0 6.6e-09 35.2 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 OEU06467.1 - 2.4e-23 81.6 9.8 4e-07 30.1 0.0 5.9 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OEU06467.1 - 9.2e-23 80.0 5.1 7.4e-06 26.1 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OEU06467.1 - 7.4e-20 70.1 10.7 4.4e-05 23.3 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OEU06467.1 - 3.6e-12 46.0 6.4 0.00013 21.9 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Mpv17_PMP22 PF04117.12 OEU06468.1 - 8.6e-15 54.7 2.9 1.7e-14 53.8 2.9 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family EP400_N PF15790.5 OEU06469.1 - 0.15 10.9 0.1 0.18 10.6 0.1 1.0 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Presenilin PF01080.17 OEU06471.1 - 0.09 11.5 15.2 0.11 11.3 15.2 1.0 1 0 0 1 1 1 0 Presenilin FAM222A PF15258.6 OEU06471.1 - 0.13 11.3 25.4 0.15 11.1 25.4 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Nop53 PF07767.11 OEU06471.1 - 1.1 8.6 35.6 1.3 8.4 35.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM176 PF14851.6 OEU06471.1 - 1.4 8.5 13.7 0.1 12.2 7.4 1.9 1 1 1 2 2 2 0 FAM176 family PfkB PF00294.24 OEU06471.1 - 1.5 8.0 3.8 1.9 7.7 3.8 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase AAA_11 PF13086.6 OEU06471.1 - 2.4 7.9 18.2 3.5 7.3 18.2 1.3 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 OEU06471.1 - 2.6 8.0 32.2 3.1 7.7 32.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 OEU06471.1 - 3.3 6.0 4.1 3.5 5.9 4.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Asp-B-Hydro_N PF05279.11 OEU06471.1 - 6.8 6.7 16.5 8.7 6.3 16.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.12 OEU06471.1 - 7.7 5.4 22.5 9.4 5.1 22.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DnaJ PF00226.31 OEU06474.1 - 1.9e-05 24.7 0.1 4.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Rib_hydrolayse PF02267.17 OEU06475.1 - 3.7e-07 29.8 0.4 0.0038 16.7 0.2 2.3 2 0 0 2 2 2 2 ADP-ribosyl cyclase PseudoU_synth_2 PF00849.22 OEU06476.1 - 1.3e-29 103.4 0.1 2.1e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF4879 PF16219.5 OEU06477.1 - 0.038 14.2 2.0 3.9 7.7 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4879) FAR1 PF03101.15 OEU06477.1 - 0.17 12.6 3.3 0.76 10.5 3.3 2.1 1 0 0 1 1 1 0 FAR1 DNA-binding domain Sporozoite_P67 PF05642.11 OEU06479.1 - 0.15 10.1 4.8 0.21 9.6 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.8 OEU06479.1 - 0.91 9.7 10.6 1.9 8.7 10.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 OEU06479.1 - 4.1 7.1 12.0 7.2 6.3 12.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-MYND PF01753.18 OEU06480.1 - 1.6e-09 37.7 16.2 1.6e-09 37.7 16.2 1.8 2 0 0 2 2 2 1 MYND finger T3RM_EcoP15I_C PF18273.1 OEU06480.1 - 0.013 15.8 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain RasGEF_N PF00618.20 OEU06480.1 - 0.081 13.2 0.1 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif zf-C6H2 PF15801.5 OEU06480.1 - 1.7 9.0 13.4 3.7 7.9 13.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CENP-F_leu_zip PF10473.9 OEU06481.1 - 0.00091 19.3 11.3 0.00091 19.3 11.3 4.7 1 1 2 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 OEU06481.1 - 0.021 14.9 6.0 0.021 14.9 6.0 4.9 1 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 OEU06481.1 - 0.045 13.6 56.6 0.088 12.6 17.6 3.8 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 OEU06481.1 - 0.81 9.9 50.8 2.9 8.1 19.3 3.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2461 PF09365.10 OEU06481.1 - 1.8 8.5 7.1 2.6 8.0 0.3 3.2 2 1 1 3 3 3 0 Conserved hypothetical protein (DUF2461) GAS PF13851.6 OEU06481.1 - 4 6.8 55.0 0.94 8.8 16.4 4.1 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OEU06481.1 - 5.1 5.9 54.2 0.53 9.1 15.9 3.9 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF745 PF05335.13 OEU06481.1 - 9 6.0 33.7 0.67 9.6 8.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Leu_zip PF15294.6 OEU06481.1 - 9 5.7 45.8 0.32 10.5 16.0 3.2 1 1 2 3 3 3 0 Leucine zipper Mpv17_PMP22 PF04117.12 OEU06482.1 - 9.6e-15 54.6 0.1 7.1e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family vMSA PF00695.19 OEU06483.1 - 0.00069 18.8 0.5 0.00069 18.8 0.5 1.4 2 0 0 2 2 2 1 Major surface antigen from hepadnavirus CD225 PF04505.12 OEU06483.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.3 3 1 1 4 4 4 0 Interferon-induced transmembrane protein GBP_C PF02841.14 OEU06484.1 - 0.089 12.2 10.3 0.69 9.3 2.8 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Macro PF01661.21 OEU06485.1 - 2.3e-07 30.9 0.2 0.012 15.6 0.0 3.0 2 1 0 2 2 2 2 Macro domain DUF4113 PF13438.6 OEU06485.1 - 0.026 14.6 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) CxC4 PF18717.1 OEU06486.1 - 0.0062 16.4 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases GWT1 PF06423.12 OEU06486.1 - 0.22 11.7 4.9 18 5.4 0.0 3.8 2 1 1 3 3 3 0 GWT1 HSF_DNA-bind PF00447.17 OEU06488.1 - 9.2e-28 96.7 1.1 2.3e-27 95.4 1.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4988 PF16378.5 OEU06488.1 - 0.0018 18.0 1.4 0.0039 16.9 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF2457 PF10446.9 OEU06488.1 - 0.45 9.6 18.5 0.41 9.7 12.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ax_dynein_light PF10211.9 OEU06488.1 - 0.53 10.2 7.3 0.16 11.9 2.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Syntaxin-6_N PF09177.11 OEU06488.1 - 3.5 8.2 8.3 4.3 8.0 1.7 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HWE_HK PF07536.14 OEU06488.1 - 9.9 6.9 7.8 2.6 8.8 0.6 2.8 3 0 0 3 3 3 0 HWE histidine kinase Tic110 PF16940.5 OEU06489.1 - 0.018 13.5 0.0 0.021 13.4 0.0 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter Dirigent PF03018.14 OEU06491.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Dirigent-like protein DNA_topoisoIV PF00521.20 OEU06492.1 - 3.2e-134 448.0 0.9 2.5e-115 385.8 0.0 2.2 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 OEU06492.1 - 4.5e-56 186.1 10.7 1.9e-11 43.2 0.1 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller NYD-SP28 PF14772.6 OEU06492.1 - 0.0025 17.8 0.6 0.0025 17.8 0.6 2.2 2 0 0 2 2 2 1 Sperm tail SR-25 PF10500.9 OEU06492.1 - 0.017 14.7 11.9 0.011 15.3 5.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FliT PF05400.13 OEU06492.1 - 0.1 13.4 0.5 0.36 11.7 0.5 1.9 1 0 0 1 1 1 0 Flagellar protein FliT Sugar_tr PF00083.24 OEU06493.1 - 4.5e-113 378.5 23.8 5.3e-113 378.3 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU06493.1 - 1.3e-30 106.5 36.3 4e-27 95.1 27.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUSP PF06337.12 OEU06494.1 - 0.058 14.0 0.7 1.7 9.3 0.1 2.4 1 1 1 2 2 2 0 DUSP domain p450 PF00067.22 OEU06496.1 - 2.9e-49 168.1 0.0 3.9e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_UBOX PF13445.6 OEU06497.1 - 5.1e-05 23.2 0.8 5.1e-05 23.2 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU06497.1 - 6.4e-05 22.7 1.7 0.0011 18.8 0.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU06497.1 - 9.2e-05 22.3 2.0 0.00057 19.8 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OEU06497.1 - 0.0016 18.7 6.3 0.0023 18.3 0.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU06497.1 - 0.012 15.4 4.5 0.026 14.4 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU06497.1 - 0.17 11.8 6.7 0.067 13.1 0.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU06497.1 - 0.26 11.2 8.8 42 4.1 5.0 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF1178 PF06676.11 OEU06497.1 - 0.69 10.3 0.0 0.69 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) Caskin-Pro-rich PF16907.5 OEU06497.1 - 6.2 7.4 14.6 0.8 10.3 2.5 3.3 3 0 0 3 3 3 0 Proline rich region of Caskin proteins PTR2 PF00854.21 OEU06498.1 - 3.9e-53 180.7 19.8 2.1e-51 175.0 19.8 2.1 1 1 0 1 1 1 1 POT family NIPSNAP PF07978.13 OEU06499.1 - 4.6e-12 46.0 0.0 6.5e-06 26.3 0.0 2.4 2 1 0 2 2 2 2 NIPSNAP DUF3446 PF11928.8 OEU06500.1 - 0.0042 17.4 5.8 0.75 10.1 0.8 2.6 2 0 0 2 2 2 2 Early growth response N-terminal domain SPX PF03105.19 OEU06500.1 - 0.85 9.5 11.6 0.34 10.8 7.8 1.8 2 0 0 2 2 2 0 SPX domain Serinc PF03348.15 OEU06500.1 - 8.9 5.1 6.7 21 3.9 0.2 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) HLH PF00010.26 OEU06501.1 - 0.0014 18.5 0.3 0.003 17.5 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_2 PF07719.17 OEU06502.1 - 0.23 11.7 4.3 0.081 13.1 1.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribul_P_3_epim PF00834.19 OEU06503.1 - 9.8e-63 211.1 0.0 1.4e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Lipase_GDSL PF00657.22 OEU06505.1 - 3.2e-06 27.2 0.0 4.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_4 PF01565.23 OEU06506.1 - 2.8e-11 43.3 2.4 2.1e-10 40.5 2.4 2.2 1 1 0 1 1 1 1 FAD binding domain DEAD PF00270.29 OEU06508.1 - 5.1e-39 133.8 0.2 1.5e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU06508.1 - 1.2e-22 80.4 0.8 1.8e-21 76.6 0.5 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU06508.1 - 0.0005 19.3 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OEU06508.1 - 0.0012 18.9 0.2 0.039 14.0 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 OEU06508.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain HLH PF00010.26 OEU06509.1 - 8.7e-05 22.4 0.0 0.00037 20.4 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF883 PF05957.13 OEU06509.1 - 0.14 12.8 0.1 0.14 12.8 0.1 3.4 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) APH PF01636.23 OEU06511.1 - 5e-06 26.6 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OEU06511.1 - 5.7e-06 25.8 0.0 9.6e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OEU06511.1 - 0.00029 20.5 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Nepo_coat_C PF03688.14 OEU06511.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Cyt-b5 PF00173.28 OEU06512.1 - 8.2e-13 48.3 0.1 1.2e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain S_2TMBeta PF18153.1 OEU06513.1 - 0.087 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain IQ PF00612.27 OEU06514.1 - 0.0068 16.1 3.9 0.39 10.6 0.8 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif Pkinase PF00069.25 OEU06515.1 - 3.6e-05 23.3 0.1 0.00013 21.4 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OEU06515.1 - 0.00095 19.7 0.1 0.0071 16.9 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ribonuc_2-5A PF06479.12 OEU06515.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease 2-5A Ank PF00023.30 OEU06515.1 - 0.23 12.0 1.6 3.1 8.4 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat PLA2G12 PF06951.11 OEU06516.1 - 0.00088 19.2 6.8 0.00088 19.2 6.8 2.5 2 0 0 2 2 2 1 Group XII secretory phospholipase A2 precursor (PLA2G12) RGCC PF15151.6 OEU06519.1 - 0.079 13.2 4.4 0.13 12.5 1.3 2.4 2 0 0 2 2 2 0 Response gene to complement 32 protein family MazG-like PF12643.7 OEU06521.1 - 0.0015 18.8 0.6 0.72 10.2 0.1 2.6 2 0 0 2 2 2 2 MazG-like family MazG PF03819.17 OEU06521.1 - 0.067 13.4 2.8 0.27 11.4 0.9 2.6 2 1 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain PUD1_2 PF18457.1 OEU06522.1 - 0.038 14.0 0.4 0.067 13.2 0.4 1.3 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 Sulfotransfer_4 PF17784.1 OEU06523.1 - 2.2e-35 122.5 0.1 4e-35 121.6 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Zip PF02535.22 OEU06524.1 - 1.4e-35 123.1 3.4 1.9e-35 122.7 3.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MNHE PF01899.16 OEU06524.1 - 7.9 6.2 7.4 1.6 8.5 1.5 2.5 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DpnI PF06044.12 OEU06527.1 - 0.0051 16.5 0.3 0.0099 15.5 0.3 1.5 1 0 0 1 1 1 1 Dam-replacing family CelTOS PF18659.1 OEU06527.1 - 0.2 12.1 1.3 1.2 9.5 0.2 2.5 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites HypA PF01155.19 OEU06527.1 - 1.1 9.3 6.1 1.9 8.5 0.2 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EcKinase PF02958.20 OEU06528.1 - 1.9e-08 34.0 1.7 0.0014 18.0 0.0 3.2 3 0 0 3 3 3 2 Ecdysteroid kinase APH PF01636.23 OEU06528.1 - 2.9e-05 24.1 0.1 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 OEU06528.1 - 0.0014 17.5 0.1 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) DUF1168 PF06658.12 OEU06529.1 - 1.6e-21 76.6 15.9 1.6e-21 76.6 15.9 3.2 2 2 0 2 2 2 1 Protein of unknown function (DUF1168) Init_tRNA_PT PF04179.12 OEU06532.1 - 2.8e-12 46.9 0.6 2.1e-07 31.2 0.0 3.1 3 0 0 3 3 3 2 Rit1 DUSP-like domain Rit1_C PF17184.4 OEU06532.1 - 7.2e-12 45.3 0.9 1.5e-11 44.3 0.2 1.8 1 1 1 2 2 2 1 Rit1 N-terminal domain DSPc PF00782.20 OEU06532.1 - 6.9e-08 32.4 0.0 6.9e-08 32.4 0.0 3.5 4 1 1 5 5 5 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OEU06532.1 - 0.0091 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Saf_2TM PF18303.1 OEU06533.1 - 5.3 6.6 8.0 0.55 9.8 0.2 2.6 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain SSF PF00474.17 OEU06534.1 - 1.2e-18 67.1 30.7 1.2e-18 67.1 30.7 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family NST1 PF13945.6 OEU06535.1 - 0.014 15.5 3.7 0.018 15.1 3.7 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator TPR_8 PF13181.6 OEU06537.1 - 0.022 15.0 0.1 0.066 13.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat BSP_II PF05432.11 OEU06538.1 - 0.00034 20.4 2.7 0.00045 20.0 2.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 OEU06538.1 - 0.00074 19.1 6.1 0.00074 19.1 6.1 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OEU06538.1 - 0.0015 17.0 5.3 0.0015 17.0 5.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 OEU06538.1 - 0.0015 17.1 5.0 0.0015 17.1 5.0 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2457 PF10446.9 OEU06538.1 - 0.0053 16.0 22.1 0.0069 15.6 22.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RRN3 PF05327.11 OEU06538.1 - 0.015 13.8 7.0 0.015 13.9 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OEU06538.1 - 0.019 13.2 13.9 0.022 13.0 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OEU06538.1 - 0.046 11.8 21.0 0.058 11.5 21.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 OEU06538.1 - 0.061 13.2 9.0 0.078 12.8 9.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PTPRCAP PF15713.5 OEU06538.1 - 0.071 13.4 6.0 0.11 12.8 6.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 OEU06538.1 - 0.088 12.1 7.4 0.098 12.0 7.4 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 OEU06538.1 - 0.13 11.6 23.8 0.18 11.1 23.8 1.1 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 OEU06538.1 - 0.33 11.0 13.0 0.49 10.5 13.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.11 OEU06538.1 - 0.38 10.3 12.7 0.43 10.1 12.7 1.1 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 OEU06538.1 - 0.43 9.9 8.8 0.55 9.6 8.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 OEU06538.1 - 0.71 10.1 19.1 1 9.6 19.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.16 OEU06538.1 - 3.3 6.8 6.0 4.3 6.5 6.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2076 PF09849.9 OEU06538.1 - 5.4 7.0 15.9 6.6 6.7 15.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4637 PF15470.6 OEU06538.1 - 7.7 6.2 9.7 12 5.6 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ste5_C PF12194.8 OEU06539.1 - 0.0085 16.1 0.6 0.011 15.7 0.6 1.1 1 0 0 1 1 1 1 Protein kinase Fus3-binding Fasciclin PF02469.22 OEU06541.1 - 8.3e-17 61.6 0.0 1.7e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Fasciclin domain CytB6-F_Fe-S PF08802.10 OEU06541.1 - 0.23 11.5 0.6 0.39 10.8 0.6 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit HA PF03457.14 OEU06542.1 - 6.5e-42 141.7 2.8 1.3e-20 73.4 0.3 2.1 2 0 0 2 2 2 2 Helicase associated domain GST_N_2 PF13409.6 OEU06544.1 - 5.3e-17 61.9 0.1 1.8e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU06544.1 - 8.2e-13 48.6 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU06544.1 - 6.2e-10 39.0 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU06544.1 - 4.3e-09 36.5 0.0 7.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU06544.1 - 4.3e-08 33.3 0.1 7.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OEU06544.1 - 8e-07 29.6 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU06544.1 - 5.5e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU06544.1 - 0.0071 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin CUE PF02845.16 OEU06545.1 - 8.8e-06 25.3 0.0 2.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 CUE domain Yae1_N PF09811.9 OEU06548.1 - 9.4e-12 44.4 50.5 0.036 13.8 3.6 12.3 3 2 6 9 9 9 8 Essential protein Yae1, N terminal DUF826 PF05696.11 OEU06548.1 - 0.11 12.6 0.4 53 4.0 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF826) DUF697 PF05128.12 OEU06548.1 - 0.91 9.2 12.0 0.75 9.5 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF697) MspA PF09203.11 OEU06548.1 - 1.7 8.5 6.8 11 5.9 1.0 3.3 1 1 1 2 2 2 0 MspA Glutaredoxin PF00462.24 OEU06550.1 - 2.2e-10 40.6 0.1 4.6e-10 39.6 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OEU06550.1 - 0.0029 18.0 0.2 0.0036 17.7 0.2 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU06550.1 - 0.003 17.3 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 OEU06550.1 - 0.0066 16.8 0.0 0.0078 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 OEU06550.1 - 0.0072 16.5 0.5 0.17 12.0 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 OEU06550.1 - 0.034 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Pol_alpha_B_N PF08418.10 OEU06550.1 - 0.064 13.2 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Thioredoxin_3 PF13192.6 OEU06550.1 - 0.072 13.2 0.1 0.35 10.9 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.6 OEU06550.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 OEU06550.1 - 0.14 11.9 1.7 0.25 11.1 0.3 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain IQ PF00612.27 OEU06551.1 - 2.7e-06 26.7 8.1 0.0037 16.9 1.2 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif E2F_CC-MB PF16421.5 OEU06551.1 - 8.3 6.8 10.5 0.71 10.3 0.3 3.2 3 1 0 3 3 3 0 E2F transcription factor CC-MB domain Fcf1 PF04900.12 OEU06552.1 - 0.0011 19.3 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Fcf1 HydF_tetramer PF18133.1 OEU06552.1 - 0.025 14.3 0.1 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Hydrogen maturase F tetramerization domain PT PF04886.12 OEU06553.1 - 4e-19 67.8 74.8 0.00016 21.2 9.8 6.6 1 1 2 3 3 3 2 PT repeat Yae1_N PF09811.9 OEU06554.1 - 5.1e-11 42.1 56.1 1.7 8.4 3.3 13.0 3 2 4 7 7 7 6 Essential protein Yae1, N terminal MspA PF09203.11 OEU06554.1 - 0.95 9.3 11.2 5.7e+03 -3.0 11.2 4.1 1 1 0 1 1 1 0 MspA DUF4691 PF15762.5 OEU06554.1 - 0.97 9.6 3.7 2.1e+02 2.0 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4691) LEM PF03020.15 OEU06554.1 - 9.1 5.9 12.0 20 4.8 0.1 5.7 5 0 0 5 5 5 0 LEM domain PT PF04886.12 OEU06555.1 - 4.9e-08 32.4 22.9 0.32 10.6 22.9 2.2 1 1 0 1 1 1 1 PT repeat LCE PF14672.6 OEU06557.1 - 0.0036 17.9 0.8 0.0036 17.9 0.8 1.7 2 0 0 2 2 2 1 Late cornified envelope Fasciclin PF02469.22 OEU06558.1 - 5.5e-07 29.9 0.0 1.2e-05 25.6 0.0 2.3 1 1 0 1 1 1 1 Fasciclin domain zf-MYND PF01753.18 OEU06559.1 - 3.9e-06 26.8 16.2 8.4e-06 25.8 16.2 1.6 1 0 0 1 1 1 1 MYND finger 1-cysPrx_C PF10417.9 OEU06559.1 - 0.16 11.8 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin FAM176 PF14851.6 OEU06559.1 - 2.8 7.6 5.2 85 2.8 0.0 2.5 2 0 0 2 2 2 0 FAM176 family SET PF00856.28 OEU06560.1 - 1.6e-06 28.6 0.0 0.025 15.0 0.0 3.7 2 2 0 2 2 2 2 SET domain CENP-B_dimeris PF09026.10 OEU06561.1 - 0.0082 16.5 0.3 0.0082 16.5 0.3 2.8 2 1 0 2 2 2 1 Centromere protein B dimerisation domain SDA1 PF05285.12 OEU06561.1 - 0.075 12.4 6.4 0.22 10.9 4.5 2.0 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 OEU06561.1 - 0.36 9.0 8.5 0.22 9.7 5.3 1.9 2 0 0 2 2 2 0 Nop14-like family Sigma70_ner PF04546.13 OEU06561.1 - 0.41 10.5 6.9 0.95 9.3 2.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2052 PF09747.9 OEU06561.1 - 0.51 10.4 9.1 0.1 12.7 2.4 2.1 1 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 OEU06561.1 - 3.9 6.7 12.9 7.8 5.7 12.9 1.5 1 1 0 1 1 1 0 BUD22 TFIIA PF03153.13 OEU06562.1 - 0.0075 16.3 8.9 0.012 15.7 8.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SRC-1 PF08832.10 OEU06562.1 - 0.064 14.3 0.5 0.064 14.3 0.5 2.7 3 0 0 3 3 3 0 Steroid receptor coactivator DUF5383 PF17355.2 OEU06562.1 - 3.2 8.1 6.4 3 8.2 0.0 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5383) CPSF100_C PF13299.6 OEU06562.1 - 4.7 7.4 11.6 2.5 8.2 0.5 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Ndc1_Nup PF09531.10 OEU06563.1 - 0.038 12.7 3.7 0.04 12.6 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup vATP-synt_E PF01991.18 OEU06563.1 - 0.039 13.3 1.2 0.083 12.3 0.4 1.8 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit PAP1 PF08601.10 OEU06563.1 - 0.51 10.0 13.9 0.7 9.6 13.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 EFG_C PF00679.24 OEU06566.1 - 0.11 12.5 0.1 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G C-terminus TFIIA_gamma_N PF02268.16 OEU06566.1 - 0.18 11.9 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF3494 PF11999.8 OEU06569.1 - 5.7e-56 189.5 16.3 7.6e-56 189.0 16.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) BUD22 PF09073.10 OEU06570.1 - 4.4 6.5 16.4 5.2 6.3 16.4 1.0 1 0 0 1 1 1 0 BUD22 Peptidase_C1 PF00112.23 OEU06571.1 - 9.9e-05 22.5 0.2 0.00018 21.7 0.0 1.6 2 0 0 2 2 2 1 Papain family cysteine protease HSF_DNA-bind PF00447.17 OEU06573.1 - 2.4e-09 37.7 1.5 5.9e-09 36.4 0.0 2.3 3 0 0 3 3 3 1 HSF-type DNA-binding DNA_pol_phi PF04931.13 OEU06573.1 - 0.029 12.5 0.0 0.029 12.5 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase phi BUD22 PF09073.10 OEU06573.1 - 0.047 13.0 8.4 0.07 12.5 8.4 1.2 1 0 0 1 1 1 0 BUD22 DUF285 PF03382.14 OEU06574.1 - 5.1e-30 103.7 9.9 4.9e-29 100.6 10.0 1.8 1 1 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 PT PF04886.12 OEU06574.1 - 0.0018 17.8 9.1 0.0033 16.9 9.1 1.4 1 0 0 1 1 1 1 PT repeat TFIIA PF03153.13 OEU06576.1 - 0.72 9.8 20.7 0.88 9.5 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit REV PF00424.18 OEU06578.1 - 0.16 12.0 2.8 0.62 10.1 2.8 1.9 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) SPT6_acidic PF14632.6 OEU06578.1 - 2.7 8.6 9.6 4.6 7.9 3.1 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DnaJ PF00226.31 OEU06579.1 - 6.3e-22 77.5 0.5 6.9e-22 77.3 0.5 1.0 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 OEU06580.1 - 0.055 13.5 14.3 0.07 13.1 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIT PF04212.18 OEU06580.1 - 0.18 11.9 3.5 0.42 10.7 0.2 3.0 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Presenilin PF01080.17 OEU06580.1 - 9.3 4.9 5.8 12 4.6 5.8 1.2 1 0 0 1 1 1 0 Presenilin Acyl_transf_3 PF01757.22 OEU06581.1 - 1.6e-13 50.5 4.5 1.6e-13 50.5 4.5 2.1 2 0 0 2 2 2 2 Acyltransferase family F-box-like PF12937.7 OEU06583.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU06583.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 OEU06584.1 - 0.00046 20.5 2.9 0.06 13.8 0.2 4.1 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 OEU06584.1 - 0.005 16.7 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OEU06584.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 OEU06584.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box PT PF04886.12 OEU06585.1 - 0.14 11.7 13.5 71 3.1 13.5 3.3 1 1 0 1 1 1 0 PT repeat Dirigent PF03018.14 OEU06586.1 - 0.14 12.0 0.4 0.29 10.9 0.4 1.5 1 0 0 1 1 1 0 Dirigent-like protein ImmE5 PF11480.8 OEU06587.1 - 6.6 7.3 8.0 0.99 9.9 3.1 2.2 1 1 1 2 2 2 0 Colicin-E5 Imm protein SDF PF00375.18 OEU06588.1 - 1.1e-17 64.1 6.3 1.3e-17 64.0 6.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Biotin_lipoyl PF00364.22 OEU06590.1 - 0.00043 20.1 0.0 0.00087 19.1 0.0 1.5 1 1 0 1 1 1 1 Biotin-requiring enzyme Orf78 PF06024.12 OEU06591.1 - 1.4 9.2 6.1 0.24 11.7 0.3 2.5 3 0 0 3 3 3 0 Orf78 (ac78) DnaJ PF00226.31 OEU06593.1 - 6.4e-08 32.6 0.0 8.7e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain bHLH-MYC_N PF14215.6 OEU06593.1 - 0.055 13.7 2.8 0.24 11.7 0.3 2.1 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Caldesmon PF02029.15 OEU06593.1 - 0.097 11.4 16.3 0.14 10.9 3.1 2.0 2 0 0 2 2 2 0 Caldesmon Pkinase PF00069.25 OEU06594.1 - 2e-28 99.5 0.0 2.4e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU06594.1 - 8.9e-25 87.4 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU06594.1 - 0.0022 17.4 0.0 0.01 15.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like AAA_6 PF12774.7 OEU06594.1 - 0.038 13.0 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region HTH_Tnp_Tc3_2 PF01498.18 OEU06596.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Transposase Yae1_N PF09811.9 OEU06598.1 - 2.2e-05 24.1 48.6 0.35 10.6 3.2 11.3 6 4 2 8 8 8 7 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU06598.1 - 0.042 14.0 0.0 12 5.9 0.0 3.3 1 1 2 3 3 3 0 Outer membrane protein beta-barrel domain MspA PF09203.11 OEU06598.1 - 2.1 8.2 3.8 1.2e+02 2.5 3.8 3.1 1 1 0 1 1 1 0 MspA AOX PF01786.17 OEU06599.1 - 1.3e-09 37.9 0.2 0.00076 19.1 0.1 2.5 2 1 0 2 2 2 2 Alternative oxidase Androgen_recep PF02166.16 OEU06599.1 - 0.39 9.5 4.1 5 5.9 0.2 2.4 2 0 0 2 2 2 0 Androgen receptor Serinc PF03348.15 OEU06599.1 - 5.7 5.8 8.1 1.4 7.7 3.7 2.1 1 1 2 3 3 3 0 Serine incorporator (Serinc) DUF285 PF03382.14 OEU06600.1 - 8.8e-61 203.0 39.1 5.7e-23 81.0 9.7 3.7 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 Phage_tail_2 PF06199.11 OEU06600.1 - 0.00012 22.1 3.3 0.12 12.5 0.1 4.2 2 2 3 5 5 5 2 Phage tail tube protein GATase_7 PF13537.6 OEU06600.1 - 0.18 11.7 2.9 25 4.8 0.0 3.5 3 1 1 4 4 4 0 Glutamine amidotransferase domain Metallophos_2 PF12850.7 OEU06601.1 - 2.5e-07 31.0 0.3 0.029 14.6 0.0 3.4 2 1 1 3 3 3 3 Calcineurin-like phosphoesterase superfamily domain DUF3335 PF11814.8 OEU06601.1 - 0.66 9.4 4.6 0.77 9.2 0.5 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family SDF PF00375.18 OEU06602.1 - 1.8e-81 274.2 34.1 7.5e-81 272.1 34.1 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family ATP-grasp_4 PF13535.6 OEU06603.1 - 8.6e-07 28.7 0.0 0.014 15.0 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 OEU06603.1 - 3.1e-05 24.1 0.0 6.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OEU06603.1 - 7e-05 22.7 0.0 0.057 13.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Lyase_N PF09092.11 OEU06603.1 - 0.16 11.8 0.0 8.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Lyase, N terminal HA PF03457.14 OEU06604.1 - 9.6e-31 105.9 7.8 1.5e-16 60.5 1.4 2.4 2 0 0 2 2 2 2 Helicase associated domain PhoH PF02562.16 OEU06604.1 - 0.0019 17.7 0.2 0.0044 16.5 0.2 1.6 1 0 0 1 1 1 1 PhoH-like protein MMR_HSR1 PF01926.23 OEU06604.1 - 0.0091 16.1 0.6 0.096 12.8 0.1 3.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase SRP54 PF00448.22 OEU06604.1 - 0.09 12.4 0.6 0.78 9.3 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MqsR_toxin PF15723.5 OEU06604.1 - 0.14 12.5 1.9 2 8.9 0.5 2.5 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA ApoLp-III PF07464.11 OEU06604.1 - 0.46 10.6 8.7 37 4.4 0.1 4.8 5 1 0 5 5 5 0 Apolipophorin-III precursor (apoLp-III) APG17 PF04108.12 OEU06604.1 - 0.57 9.2 9.9 1.6 7.8 2.5 2.9 2 2 0 2 2 2 0 Autophagy protein Apg17 Cnd1 PF12717.7 OEU06604.1 - 0.62 10.1 3.8 23 5.0 0.0 3.7 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HA PF03457.14 OEU06605.1 - 1.9e-32 111.4 2.2 4.3e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 Helicase associated domain NPAT_C PF15712.5 OEU06609.1 - 6.4 5.3 15.6 11 4.5 15.6 1.3 1 0 0 1 1 1 0 NPAT C terminus zf-C2H2 PF00096.26 OEU06613.1 - 0.0061 17.0 0.5 0.0061 17.0 0.5 8.2 8 1 1 9 9 9 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OEU06613.1 - 0.042 14.7 0.4 0.042 14.7 0.4 10.2 12 0 0 12 12 12 0 C2H2-type zinc finger PyrI_C PF02748.15 OEU06613.1 - 0.18 11.7 25.2 19 5.2 0.1 7.7 8 0 0 8 8 8 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C2 PF00168.30 OEU06614.1 - 1.4e-24 86.3 0.0 2.7e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain Glucan_synthase PF02364.15 OEU06614.1 - 0.11 10.7 1.2 0.17 10.0 1.2 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase component FAM217 PF15344.6 OEU06614.1 - 0.56 10.1 4.3 1.2 9.0 4.3 1.5 1 0 0 1 1 1 0 FAM217 family HA PF03457.14 OEU06615.1 - 2.4e-64 213.6 16.4 2.6e-16 59.7 1.2 4.0 4 0 0 4 4 4 4 Helicase associated domain ELL PF10390.9 OEU06615.1 - 4.7e-09 36.2 0.0 0.0018 17.9 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase II elongation factor ELL Ribosomal_L7Ae PF01248.26 OEU06615.1 - 0.00051 19.7 0.0 3.2 7.5 0.0 3.7 4 0 0 4 4 4 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3836 PF12930.7 OEU06615.1 - 0.029 14.1 4.1 3 7.6 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF3836) Get5_bdg PF16843.5 OEU06615.1 - 0.081 12.4 0.0 12 5.5 0.0 2.8 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein YhdB PF14148.6 OEU06615.1 - 0.8 9.8 3.6 41 4.4 0.1 3.2 3 0 0 3 3 3 0 YhdB-like protein TF_AP-2 PF03299.14 OEU06615.1 - 2.5 8.0 4.4 16 5.4 0.0 3.0 3 0 0 3 3 3 0 Transcription factor AP-2 COMPASS-Shg1 PF05205.12 OEU06615.1 - 4.7 8.0 7.6 61 4.4 0.3 3.3 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 Dehydrin PF00257.19 OEU06615.1 - 7.9 7.0 9.5 15 6.1 0.2 3.0 3 0 0 3 3 3 0 Dehydrin MFS_1 PF07690.16 OEU06616.1 - 1.3e-15 57.2 27.6 3.8e-09 35.9 7.2 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4491 PF14898.6 OEU06616.1 - 0.1 13.1 6.3 1.1 9.7 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) DNA_pol_A_exo1 PF01612.20 OEU06617.1 - 3.3e-08 33.5 0.0 1.5e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 3'-5' exonuclease Androgen_recep PF02166.16 OEU06617.1 - 4.8 5.9 6.1 2 7.2 2.1 2.4 2 0 0 2 2 2 0 Androgen receptor RNA_pol_Rpb2_7 PF04560.20 OEU06618.1 - 0.39 11.1 2.8 9.7 6.7 0.1 3.1 4 0 0 4 4 4 0 RNA polymerase Rpb2, domain 7 K_oxygenase PF13434.6 OEU06619.1 - 1.4e-10 40.8 0.0 2.8e-08 33.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OEU06619.1 - 0.00057 19.2 0.0 0.029 13.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU06619.1 - 0.12 12.4 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding TFIIA PF03153.13 OEU06620.1 - 0.31 11.0 57.8 0.058 13.4 10.0 3.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit G-patch PF01585.23 OEU06622.1 - 1.6e-09 37.5 3.0 5.7e-09 35.7 3.0 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OEU06622.1 - 1.2e-06 28.5 1.3 1.2e-06 28.5 1.3 3.3 3 0 0 3 3 3 1 G-patch domain DASH_Dad2 PF08654.10 OEU06622.1 - 0.0066 16.9 1.2 0.0066 16.9 1.2 2.4 1 1 1 2 2 2 1 DASH complex subunit Dad2 DUF4604 PF15377.6 OEU06622.1 - 0.01 16.3 27.6 0.056 13.9 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DTHCT PF08070.11 OEU06622.1 - 0.15 12.8 32.4 0.25 12.1 5.3 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region RNA_polI_A34 PF08208.11 OEU06622.1 - 0.19 11.8 34.7 0.14 12.2 8.8 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 OEU06622.1 - 0.2 11.2 32.0 0.017 14.8 7.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3915 PF13054.6 OEU06622.1 - 0.26 11.3 2.3 1.6 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) HA2 PF04408.23 OEU06622.1 - 0.28 11.5 6.3 2.8 8.3 1.4 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) Coilin_N PF15862.5 OEU06622.1 - 0.6 9.9 25.9 1.8 8.4 13.7 2.2 2 0 0 2 2 2 0 Coilin N-terminus RPN2_C PF18004.1 OEU06622.1 - 0.63 9.9 25.0 1.5 8.7 3.0 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1840 PF08895.11 OEU06622.1 - 1.3 9.4 10.6 4.3 7.7 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 OEU06622.1 - 1.6 8.4 8.9 8.2 6.1 0.3 2.2 2 0 0 2 2 2 0 FAM176 family Vfa1 PF08432.10 OEU06622.1 - 1.8 8.9 23.3 2 8.7 3.7 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GEN1_C PF18380.1 OEU06622.1 - 3.1 8.7 11.3 2.8 8.9 0.3 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Eapp_C PF10238.9 OEU06622.1 - 3.5 7.7 14.9 3.4 7.7 0.5 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein PRC2_HTH_1 PF18118.1 OEU06622.1 - 3.6 8.4 15.5 4.3 8.2 0.8 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain U1snRNP70_N PF12220.8 OEU06622.1 - 4 8.1 16.7 3 8.6 0.9 2.6 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ArAE_2_N PF10337.9 OEU06622.1 - 6.4 5.7 6.0 7.5 5.5 6.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal STAG PF08514.11 OEU06622.1 - 7.6 6.5 13.0 9.4 6.2 6.4 2.3 2 0 0 2 2 2 0 STAG domain Ribosomal_60s PF00428.19 OEU06622.1 - 7.7 7.2 14.6 3.7 8.2 5.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peroxin-13_N PF04088.13 OEU06622.1 - 8 6.7 6.9 5.6 7.2 1.9 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Med26_C PF15693.5 OEU06622.1 - 8.6 6.5 11.8 3.4 7.8 6.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal DUF3494 PF11999.8 OEU06623.1 - 8.1e-77 257.6 58.1 3.2e-25 89.0 15.5 5.3 3 3 0 3 3 3 3 Protein of unknown function (DUF3494) Baculo_11_kDa PF06143.11 OEU06623.1 - 8.9 6.0 9.3 16 5.2 9.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5316 PF17247.2 OEU06624.1 - 1.8 8.6 5.5 5.3 7.1 0.1 3.4 2 1 0 2 2 2 0 Family of unknown function (DUF5316) PhrC_PhrF PF11131.8 OEU06624.1 - 2.3 7.9 4.9 6.7 6.4 4.9 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling PPR_1 PF12854.7 OEU06625.1 - 4.3e-39 131.9 15.9 1.3e-05 24.7 0.0 11.3 11 0 0 11 11 11 9 PPR repeat PPR_2 PF13041.6 OEU06625.1 - 4.1e-36 123.0 23.8 1.5e-07 31.5 0.1 9.3 7 4 1 8 8 8 7 PPR repeat family PPR_3 PF13812.6 OEU06625.1 - 7.7e-27 93.2 18.7 1e-07 31.9 0.1 9.2 6 3 3 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.20 OEU06625.1 - 5.1e-22 76.5 28.5 1.4e-05 25.0 0.0 12.2 12 1 0 12 12 12 5 PPR repeat PPR_long PF17177.4 OEU06625.1 - 9.7e-10 38.2 3.2 0.014 14.7 0.0 5.4 2 2 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP PLAC8 PF04749.17 OEU06627.1 - 3.3e-15 56.9 20.9 4.7e-15 56.4 20.9 1.2 1 0 0 1 1 1 1 PLAC8 family DUF1129 PF06570.11 OEU06627.1 - 0.18 11.2 0.9 0.24 10.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Pyr_redox_2 PF07992.14 OEU06628.1 - 3.4e-39 134.8 0.0 7.9e-39 133.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OEU06628.1 - 3.1e-22 78.5 0.0 9.3e-22 76.9 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 OEU06628.1 - 1.5e-15 57.0 0.0 2.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 OEU06628.1 - 8.5e-13 48.4 6.1 1.8e-11 44.2 2.4 3.0 2 1 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 OEU06628.1 - 2.7e-12 46.4 0.0 6.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 OEU06628.1 - 3.2e-11 43.0 0.0 7.5e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OEU06628.1 - 3.4e-11 43.5 2.2 5.5e-11 42.9 0.3 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 OEU06628.1 - 2.6e-08 33.6 0.0 1.1e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain GIDA PF01134.22 OEU06628.1 - 0.0023 17.1 0.6 0.86 8.6 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OEU06628.1 - 0.034 13.4 0.2 0.069 12.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OEU06628.1 - 0.17 11.1 0.5 8.6 5.5 0.8 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU06628.1 - 0.72 8.9 3.1 16 4.5 0.7 2.4 2 0 0 2 2 2 0 FAD binding domain PUB PF09409.10 OEU06631.1 - 4.3e-08 33.0 0.7 8e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 PUB domain PDZ PF00595.24 OEU06631.1 - 0.00014 22.1 0.1 0.00039 20.7 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU06631.1 - 0.00053 20.2 0.1 0.0015 18.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU06631.1 - 0.0025 17.6 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Apolipoprotein PF01442.18 OEU06635.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lipl32 PF12103.8 OEU06636.1 - 0.061 13.0 0.4 0.1 12.3 0.4 1.4 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order WES_acyltransf PF03007.16 OEU06636.1 - 0.52 10.0 4.9 2.8 7.6 0.3 2.5 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain SAT PF16073.5 OEU06637.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Haem_degrading PF03928.14 OEU06637.1 - 0.026 14.6 0.8 0.035 14.1 0.6 1.4 1 1 0 1 1 1 0 Haem-degrading GLE1 PF07817.13 OEU06637.1 - 0.028 13.6 0.4 0.036 13.3 0.4 1.1 1 0 0 1 1 1 0 GLE1-like protein DUF2075 PF09848.9 OEU06637.1 - 0.03 13.6 0.8 0.037 13.3 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.7 OEU06639.1 - 8.9e-15 55.0 0.1 2.2e-12 47.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU06639.1 - 7e-13 48.8 0.4 9.2e-10 38.9 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU06639.1 - 1.3e-10 41.3 0.4 4e-07 30.2 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU06639.1 - 3.1e-09 36.9 0.1 0.00067 20.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OEU06639.1 - 3.6e-09 36.1 0.0 0.009 16.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OEU06641.1 - 2.9e-16 59.8 0.0 3.2e-13 50.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU06641.1 - 1.4e-12 47.6 1.3 1.7e-05 25.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU06641.1 - 9.4e-12 45.2 0.5 1.4e-08 35.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU06641.1 - 1.7e-10 40.2 0.0 4.5e-06 26.6 0.0 4.3 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU06641.1 - 3.8e-09 36.6 0.0 0.0024 18.3 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat DUF333 PF03891.15 OEU06642.1 - 0.0002 21.5 0.2 0.00032 20.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF333) DUF3439 PF11921.8 OEU06643.1 - 0.091 12.7 0.2 0.091 12.7 0.2 3.0 3 1 2 5 5 5 0 Domain of unknown function (DUF3439) PRC2_HTH_1 PF18118.1 OEU06643.1 - 7.9 7.3 11.5 0.56 11.0 0.6 3.5 4 1 0 4 4 4 0 Polycomb repressive complex 2 tri-helical domain Presenilin PF01080.17 OEU06644.1 - 0.02 13.7 17.7 0.025 13.4 4.2 2.2 2 0 0 2 2 2 0 Presenilin TPR_12 PF13424.6 OEU06644.1 - 0.024 14.9 2.3 1.4 9.2 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU06644.1 - 0.038 13.8 5.2 1.3 9.0 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU06644.1 - 0.043 13.9 0.6 2.3 8.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DDHD PF02862.17 OEU06644.1 - 0.057 13.6 16.0 0.08 13.1 2.2 2.3 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.14 OEU06644.1 - 0.45 8.7 20.4 0.033 12.5 4.3 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF913 PF06025.12 OEU06644.1 - 0.76 8.7 15.7 0.53 9.2 4.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) XAP5 PF04921.14 OEU06644.1 - 1.3 8.8 16.4 0.87 9.4 5.2 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator LAP1C PF05609.12 OEU06644.1 - 2.2 7.3 23.6 0.36 9.9 4.4 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 OEU06644.1 - 2.3 8.0 17.0 0.37 10.6 5.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TCP PF03634.13 OEU06644.1 - 9.7 6.7 33.0 4.1 8.0 11.7 2.6 2 0 0 2 2 2 0 TCP family transcription factor MSC PF09402.10 OEU06645.1 - 0.96 8.8 5.6 28 4.0 5.6 2.5 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Rsa3 PF14615.6 OEU06646.1 - 5.5e-05 22.6 0.6 0.00033 20.1 0.2 2.5 2 1 0 2 2 2 1 Ribosome-assembly protein 3 Calpain_inhib PF00748.19 OEU06647.1 - 0.046 14.2 8.8 0.11 13.0 8.8 1.6 1 0 0 1 1 1 0 Calpain inhibitor Macoilin PF09726.9 OEU06647.1 - 0.1 11.2 5.6 0.093 11.3 5.6 1.1 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 OEU06647.1 - 0.33 10.1 4.6 0.47 9.6 4.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RAP1 PF07218.11 OEU06647.1 - 1.3 7.2 17.9 1.6 6.9 17.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.12 OEU06647.1 - 1.6 7.0 23.5 2.4 6.5 23.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Apt1 PF10351.9 OEU06647.1 - 2.1 7.1 5.8 2.4 6.9 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Miga PF10265.9 OEU06647.1 - 2.1 7.2 7.3 2.4 7.0 7.3 1.1 1 0 0 1 1 1 0 Mitoguardin Kinesin_assoc PF16183.5 OEU06647.1 - 3.6 7.7 9.1 83 3.3 9.0 2.2 1 1 0 1 1 1 0 Kinesin-associated PBP1_TM PF14812.6 OEU06648.1 - 0.3 11.5 9.7 0.098 13.0 5.8 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OEU06648.1 - 1.8 6.8 6.9 2 6.6 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Secretin_N_2 PF07655.13 OEU06648.1 - 2.1 8.9 7.3 3.5 8.2 2.6 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CRAL_TRIO PF00650.20 OEU06649.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain DUF4972 PF16342.5 OEU06649.1 - 0.052 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) zf-MIZ PF02891.20 OEU06649.1 - 0.065 13.0 2.1 0.16 11.7 2.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger CLN3 PF02487.17 OEU06650.1 - 1.6e-07 30.8 1.2 3.5e-07 29.6 1.2 1.7 1 1 0 1 1 1 1 CLN3 protein Ig_GlcNase PF18368.1 OEU06653.1 - 0.06 13.5 0.1 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain CNDH2_C PF16858.5 OEU06654.1 - 0.0021 18.0 2.6 0.36 10.7 0.8 2.1 2 0 0 2 2 2 2 Condensin II complex subunit CAP-H2 or CNDH2, C-term CAC1F_C PF16885.5 OEU06654.1 - 3.3 7.3 16.6 0.074 12.7 7.3 2.0 1 1 1 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term CTNNB1_binding PF08347.11 OEU06654.1 - 3.4 7.8 13.0 0.78 9.9 4.7 2.2 2 0 0 2 2 2 0 N-terminal CTNNB1 binding HAD_2 PF13419.6 OEU06655.1 - 9.5e-19 68.1 0.0 4e-18 66.1 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU06655.1 - 1e-12 48.8 0.0 2.5e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU06655.1 - 0.0026 17.8 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OEU06655.1 - 0.0051 17.2 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1223 PF06764.11 OEU06655.1 - 0.0081 16.2 0.1 0.015 15.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1223) Resolvase PF00239.21 OEU06655.1 - 0.024 14.7 0.0 0.081 13.0 0.0 1.7 2 0 0 2 2 2 0 Resolvase, N terminal domain ATP_bind_3 PF01171.20 OEU06657.1 - 3.9e-20 72.4 6.4 2.5e-07 30.6 0.0 3.8 2 1 1 3 3 3 3 PP-loop family HGD-D PF06050.13 OEU06657.1 - 0.0082 15.9 0.4 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component RNase_HII PF01351.18 OEU06657.1 - 0.064 13.1 4.7 3.6 7.4 1.2 2.9 2 1 1 3 3 3 0 Ribonuclease HII Katanin_con80 PF13925.6 OEU06659.1 - 0.012 15.6 0.3 0.02 15.0 0.3 1.2 1 0 0 1 1 1 0 con80 domain of Katanin Tudor_FRX1 PF18336.1 OEU06660.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain OFeT_1 PF16955.5 OEU06661.1 - 0.025 14.3 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter Nif11 PF07862.11 OEU06661.1 - 0.16 12.3 0.0 1.1 9.7 0.0 2.1 1 1 0 1 1 1 0 Nif11 domain hNIFK_binding PF12196.8 OEU06661.1 - 0.4 10.2 1.8 1.1 8.8 1.8 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Ank_2 PF12796.7 OEU06663.1 - 7.6e-10 39.3 0.2 2.5e-06 28.0 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU06663.1 - 3.3e-08 33.6 0.3 0.00041 20.6 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU06663.1 - 1.8e-05 25.0 2.5 0.52 10.9 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OEU06663.1 - 9.9e-05 22.5 1.6 3.3 8.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OEU06663.1 - 0.00014 22.4 1.0 0.026 15.1 0.2 3.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Myosin_head PF00063.21 OEU06664.1 - 3.2e-210 699.8 0.0 4e-210 699.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 OEU06664.1 - 2.1e-05 23.9 34.5 0.049 13.4 1.2 5.6 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_16 PF13191.6 OEU06664.1 - 0.005 17.2 0.0 0.024 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF952 PF06108.12 OEU06664.1 - 0.052 13.6 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF952) T2SSE PF00437.20 OEU06664.1 - 0.096 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 OEU06664.1 - 0.11 12.6 0.2 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tom7 PF08038.12 OEU06664.1 - 0.18 11.5 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 TOM7 family RVT_1 PF00078.27 OEU06667.1 - 1.5e-05 24.6 0.0 4.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5490 PF17593.2 OEU06667.1 - 0.0097 15.9 0.0 0.038 14.0 0.0 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5490) ATP-synt_8 PF00895.20 OEU06667.1 - 0.036 14.5 0.6 0.17 12.4 0.6 2.3 1 0 0 1 1 1 0 ATP synthase protein 8 Exo_endo_phos PF03372.23 OEU06667.1 - 0.036 13.6 0.1 0.12 11.9 0.1 1.9 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF2730 PF10805.8 OEU06667.1 - 2.8 8.1 7.3 4 7.6 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) CENP-B_dimeris PF09026.10 OEU06668.1 - 0.0053 17.1 5.9 0.0062 16.9 5.9 1.1 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OEU06668.1 - 0.71 7.9 5.4 0.71 7.9 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 OEU06668.1 - 3 6.9 7.8 3.1 6.8 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CAF1-p150_C2 PF15539.6 OEU06669.1 - 0.017 14.6 0.2 0.017 14.6 0.2 2.4 1 1 1 3 3 3 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term YtxC PF08812.11 OEU06669.1 - 0.035 13.7 0.2 0.083 12.5 0.2 1.6 1 0 0 1 1 1 0 YtxC-like family NUP50 PF08911.11 OEU06669.1 - 2.3 8.9 8.4 0.17 12.6 1.7 2.6 2 1 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Macoilin PF09726.9 OEU06669.1 - 3.5 6.1 20.0 4.4 5.7 20.0 1.0 1 0 0 1 1 1 0 Macoilin family CDV3 PF15359.6 OEU06669.1 - 6 7.4 8.5 1.2 9.6 0.5 2.4 1 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 Pro_isomerase PF00160.21 OEU06670.1 - 1.8e-41 142.0 0.1 2.3e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GWT1 PF06423.12 OEU06671.1 - 3e-18 66.4 14.9 3e-18 66.4 14.9 4.0 3 2 1 4 4 4 1 GWT1 NodZ PF05830.11 OEU06671.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Lipase_3 PF01764.25 OEU06672.1 - 1.6e-24 86.4 0.0 2.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OEU06672.1 - 0.0084 16.7 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OEU06672.1 - 0.06 12.9 0.0 0.7 9.4 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PPV_E1_N PF00524.18 OEU06673.1 - 1 9.8 5.7 96 3.4 5.7 2.6 1 1 0 1 1 1 0 E1 Protein, N terminal domain DMSP_lyase PF16867.5 OEU06674.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF1857 PF08982.11 OEU06674.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Mito_carr PF00153.27 OEU06675.1 - 9.2e-20 70.4 8.7 1.1e-06 28.5 1.4 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Wap1 PF16997.5 OEU06676.1 - 0.027 13.6 0.1 0.062 12.5 0.1 1.6 1 0 0 1 1 1 0 Wap1 domain Na_H_antiporter PF03553.14 OEU06677.1 - 2.5e-39 135.3 25.0 5.6e-27 94.8 16.4 3.5 2 1 1 3 3 3 3 Na+/H+ antiporter family PAP_fibrillin PF04755.12 OEU06678.1 - 1.7e-07 31.4 0.7 3.5e-07 30.4 0.1 1.8 1 1 1 2 2 2 1 PAP_fibrillin Ribosomal_S9 PF00380.19 OEU06678.1 - 0.066 13.7 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Glyco_hydro_17 PF00332.18 OEU06679.1 - 2.8e-07 30.5 0.7 1.4e-05 24.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Mucin PF01456.17 OEU06679.1 - 0.0028 17.7 18.6 0.0028 17.7 18.6 5.0 4 1 0 4 4 4 2 Mucin-like glycoprotein DUF3824 PF12868.7 OEU06679.1 - 0.11 13.1 0.2 0.24 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3494 PF11999.8 OEU06680.1 - 3.1e-61 206.7 10.5 4.5e-61 206.1 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) ShK PF01549.24 OEU06680.1 - 0.47 11.0 4.0 0.88 10.2 4.0 1.5 1 0 0 1 1 1 0 ShK domain-like Peptidase_S49_N PF08496.10 OEU06680.1 - 1.5 8.9 4.0 2.3 8.3 4.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LRR_6 PF13516.6 OEU06682.1 - 2.1e-26 89.7 21.0 0.00025 20.9 0.3 8.7 8 0 0 8 8 8 7 Leucine Rich repeat LRR_4 PF12799.7 OEU06682.1 - 1.7e-07 31.4 19.2 0.29 11.6 0.3 6.7 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU06682.1 - 1.4e-05 24.8 18.9 0.13 12.0 0.7 6.8 4 3 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 OEU06682.1 - 2e-05 24.5 11.3 62 4.7 0.0 8.2 8 0 0 8 8 8 0 Leucine Rich Repeat Phage_sheath_1 PF04984.14 OEU06682.1 - 0.011 15.6 0.0 5.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Pentapeptide PF00805.22 OEU06682.1 - 2.3 7.9 6.7 9.3 6.0 0.8 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) CENP-B_dimeris PF09026.10 OEU06683.1 - 0.0034 17.7 7.3 0.0054 17.1 7.3 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain FAM176 PF14851.6 OEU06683.1 - 0.042 13.5 0.3 0.042 13.5 0.3 1.7 2 0 0 2 2 2 0 FAM176 family NYAP_N PF15439.6 OEU06683.1 - 0.49 9.5 4.0 4.1 6.5 1.5 2.0 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DNA_pol_phi PF04931.13 OEU06683.1 - 1.5 6.8 9.5 2.4 6.1 9.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 OEU06684.1 - 0.014 14.8 24.0 0.019 14.4 12.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CCDC53 PF10152.9 OEU06684.1 - 0.083 13.3 22.8 0.26 11.7 7.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AF-4 PF05110.13 OEU06684.1 - 0.16 10.0 36.6 0.019 13.1 11.4 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Spem1 PF15670.5 OEU06684.1 - 0.55 9.8 26.1 0.095 12.3 7.5 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 Suf PF05843.14 OEU06684.1 - 0.74 9.7 27.9 0.18 11.8 12.3 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RskA PF10099.9 OEU06684.1 - 1.5 9.1 11.7 0.43 10.9 0.2 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Velvet PF11754.8 OEU06684.1 - 2.2 8.2 25.0 0.43 10.5 9.2 2.2 2 0 0 2 2 2 0 Velvet factor Baculo_PP31 PF05311.11 OEU06684.1 - 2.2 7.7 21.3 2.8 7.3 5.1 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF3408 PF11888.8 OEU06684.1 - 2.3 8.4 23.8 4 7.6 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MecA PF05389.12 OEU06684.1 - 3.7 7.1 19.2 3.9 7.0 9.1 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Thg1C PF14413.6 OEU06684.1 - 7.9 6.7 18.9 9.8 6.4 7.8 2.6 2 0 0 2 2 2 0 Thg1 C terminal domain F-box_4 PF15966.5 OEU06685.1 - 0.0079 16.1 2.6 0.08 12.8 0.2 2.0 1 1 1 2 2 2 2 F-box FeoB_C PF07664.12 OEU06685.1 - 0.9 9.3 4.5 0.34 10.6 1.1 2.0 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus MRI PF15325.6 OEU06686.1 - 0.0053 17.8 3.8 0.0069 17.4 3.8 1.2 1 0 0 1 1 1 1 Modulator of retrovirus infection Dmrt1 PF12374.8 OEU06686.1 - 0.18 12.3 3.3 0.18 12.3 2.2 1.7 1 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 TipE PF16972.5 OEU06686.1 - 0.77 8.9 4.4 0.87 8.7 4.4 1.0 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE FAM193_C PF15914.5 OEU06687.1 - 0.064 13.0 1.3 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 FAM193 family C-terminal DUF4699 PF15770.5 OEU06687.1 - 5.5 6.7 17.9 0.25 11.1 12.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4699) Chloroa_b-bind PF00504.21 OEU06688.1 - 4.9e-38 131.2 0.8 5.1e-20 72.6 0.0 3.6 2 2 1 3 3 3 2 Chlorophyll A-B binding protein DUF3122 PF11320.8 OEU06691.1 - 0.023 14.8 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DUF2358 PF10184.9 OEU06692.1 - 0.00097 19.4 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SOUL PF04832.12 OEU06692.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein HC2 PF07382.11 OEU06695.1 - 0.0011 19.1 54.2 0.0016 18.6 54.2 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Misat_Tub_SegII PF10644.9 OEU06696.1 - 1.2e-05 25.5 7.0 3.9e-05 23.9 0.0 3.2 1 1 0 2 2 2 1 Misato Segment II tubulin-like domain CDC45 PF02724.14 OEU06696.1 - 1.7 6.9 9.2 2.2 6.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PH_11 PF15413.6 OEU06697.1 - 0.098 13.1 0.2 0.098 13.1 0.2 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain DDE_Tnp_1 PF01609.21 OEU06698.1 - 0.0004 20.1 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain O-FucT PF10250.9 OEU06699.1 - 6.8e-09 35.9 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DDE_1 PF03184.19 OEU06700.1 - 2e-23 82.9 0.0 3.9e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OEU06700.1 - 2.1e-05 24.4 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Nas2_N PF18265.1 OEU06701.1 - 1.1e-20 73.3 0.0 1.5e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain FAM184 PF15665.5 OEU06702.1 - 0.028 14.2 0.9 0.028 14.2 0.9 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Nup54 PF13874.6 OEU06702.1 - 0.12 12.4 2.9 0.12 12.4 0.9 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 CLZ PF16526.5 OEU06702.1 - 0.27 11.6 3.1 22 5.5 0.0 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UL42 PF17638.2 OEU06703.1 - 0.77 9.7 7.9 2.3 8.2 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 Smg4_UPF3 PF03467.15 OEU06706.1 - 1.3 9.1 4.6 0.27 11.3 0.6 1.9 3 0 0 3 3 3 0 Smg-4/UPF3 family Acetyltransf_1 PF00583.25 OEU06707.1 - 2.8e-12 46.9 0.0 4.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU06707.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU06707.1 - 2.5e-05 24.6 0.1 6.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU06707.1 - 0.0066 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 OEU06707.1 - 0.0075 16.9 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OEU06707.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Viral_P18 PF04521.13 OEU06707.1 - 0.033 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein FR47 PF08445.10 OEU06707.1 - 0.09 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein GST_N PF02798.20 OEU06708.1 - 0.068 13.5 0.1 0.47 10.8 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain Methyltransf_11 PF08241.12 OEU06709.1 - 1.5e-11 44.8 0.0 3.4e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU06709.1 - 8.4e-08 32.8 0.0 1.1e-06 29.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU06709.1 - 4.3e-05 23.4 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU06709.1 - 0.00035 20.0 0.0 0.00057 19.3 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU06709.1 - 0.00051 20.7 0.0 0.0012 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU06709.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OEU06709.1 - 0.065 11.8 0.0 0.09 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 OEU06709.1 - 0.079 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 OEU06709.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Topoisom_I_N PF02919.15 OEU06711.1 - 4.2e-11 42.8 1.3 5.6e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DDHD PF02862.17 OEU06711.1 - 0.23 11.6 4.5 0.31 11.2 4.5 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 OEU06711.1 - 0.38 10.5 9.0 0.47 10.2 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 OEU06711.1 - 0.5 8.9 19.3 0.57 8.7 19.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 OEU06711.1 - 0.77 8.5 12.1 0.81 8.5 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 OEU06711.1 - 1.2 7.3 8.2 1.5 7.1 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein LEA_1 PF03760.15 OEU06711.1 - 1.5 9.5 8.1 2.2 9.0 7.4 1.7 1 1 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Ndc1_Nup PF09531.10 OEU06711.1 - 2.3 6.8 8.2 2.6 6.7 8.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF908 PF06012.12 OEU06711.1 - 2.7 7.3 8.3 3 7.1 8.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 OEU06711.1 - 7.3 5.2 6.4 7.4 5.2 6.4 1.1 1 0 0 1 1 1 0 Presenilin POX PF07526.11 OEU06713.1 - 7 7.2 6.7 7.3 7.2 0.7 2.6 2 0 0 2 2 2 0 Associated with HOX Rap1_C PF11626.8 OEU06714.1 - 0.094 12.8 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Tubulin-binding PF00418.19 OEU06714.1 - 0.98 9.5 6.6 14 5.8 0.2 3.2 3 0 0 3 3 3 0 Tau and MAP protein, tubulin-binding repeat IMUP PF15761.5 OEU06715.1 - 0.18 12.5 8.4 0.4 11.4 5.6 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein CDK2AP PF09806.9 OEU06715.1 - 8.9 6.3 12.7 0.12 12.4 4.1 1.9 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein S-methyl_trans PF02574.16 OEU06716.1 - 2.8e-52 178.2 0.0 3.3e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Sirohm_synth_C PF14823.6 OEU06718.1 - 0.03 13.9 1.0 1.6 8.4 0.3 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF1168 PF06658.12 OEU06718.1 - 0.068 13.0 3.6 0.13 12.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) LRR_8 PF13855.6 OEU06719.1 - 8.8e-11 41.4 26.8 3.1e-05 23.6 3.0 5.6 3 1 3 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 OEU06719.1 - 1.7e-08 34.6 30.5 0.0056 17.1 2.5 6.8 3 3 4 8 8 8 5 Leucine Rich repeats (2 copies) SAM_Ste50p PF09235.10 OEU06719.1 - 0.00088 19.5 0.8 11 6.4 0.0 4.5 3 2 1 4 4 4 1 Ste50p, sterile alpha motif FNIP PF05725.12 OEU06719.1 - 0.002 18.2 4.6 4.2 7.6 0.0 4.8 4 2 1 5 5 5 2 FNIP Repeat LRR_1 PF00560.33 OEU06719.1 - 0.034 14.7 29.9 4.5 8.2 0.1 8.5 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 OEU06719.1 - 0.09 12.9 14.7 2 8.7 0.2 6.0 6 0 0 6 6 6 0 Leucine Rich repeat PHD PF00628.29 OEU06722.1 - 1.8e-05 24.5 5.9 3.2e-05 23.7 5.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OEU06722.1 - 5.9e-05 22.5 0.8 5.9e-05 22.5 0.8 1.9 3 0 0 3 3 3 1 PHD-finger Hid1 PF12722.7 OEU06722.1 - 0.0037 15.5 0.1 0.0037 15.5 0.1 1.4 2 0 0 2 2 2 1 High-temperature-induced dauer-formation protein C1_1 PF00130.22 OEU06722.1 - 0.0076 16.1 2.1 0.0076 16.1 2.1 1.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 OEU06722.1 - 0.012 15.9 3.3 0.012 15.9 3.3 1.8 2 0 0 2 2 2 0 C1 domain Sigma70_ner PF04546.13 OEU06722.1 - 0.015 15.2 3.5 0.72 9.7 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.6 OEU06722.1 - 0.015 15.5 0.6 0.015 15.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-PHD-like PF15446.6 OEU06722.1 - 0.02 14.5 1.0 0.02 14.5 1.0 1.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 OEU06722.1 - 0.025 14.6 6.1 0.11 12.6 6.1 2.2 1 1 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 OEU06722.1 - 0.093 13.1 6.0 0.16 12.3 6.0 1.4 1 0 0 1 1 1 0 Ring finger domain RNA_capsid PF03035.14 OEU06722.1 - 0.21 11.6 9.4 3.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein Zf_RING PF16744.5 OEU06722.1 - 0.26 11.4 7.8 13 6.0 7.8 2.6 1 1 0 1 1 1 0 KIAA1045 RING finger DnaJ_CXXCXGXG PF00684.19 OEU06722.1 - 0.81 10.1 7.0 0.2 12.0 0.7 2.4 2 0 0 2 2 2 0 DnaJ central domain PBP1_TM PF14812.6 OEU06722.1 - 1.8 9.0 7.2 1 9.8 1.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-RING_9 PF13901.6 OEU06722.1 - 3.3 7.7 8.2 0.66 9.9 3.7 2.1 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 OEU06722.1 - 4.8 7.6 8.9 0.15 12.4 2.8 1.6 2 0 0 2 2 1 0 RING-like domain APOBEC3 PF18771.1 OEU06724.1 - 0.065 13.4 3.8 0.79 9.8 0.6 3.3 3 0 0 3 3 3 0 APOBEC3 DDT PF02791.17 OEU06724.1 - 0.081 13.2 0.0 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 DDT domain Holin_BhlA PF10960.8 OEU06724.1 - 0.11 12.4 1.0 1.6 8.8 0.4 2.6 2 0 0 2 2 2 0 BhlA holin family MCR PF18509.1 OEU06724.1 - 6.9 6.4 9.8 0.86 9.2 0.5 3.3 3 0 0 3 3 3 0 Magnetochrome domain RibD_C PF01872.17 OEU06728.1 - 0.058 13.2 1.6 0.075 12.9 0.5 1.7 2 0 0 2 2 2 0 RibD C-terminal domain DUF4224 PF13986.6 OEU06728.1 - 0.07 13.0 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Ly49 PF08391.10 OEU06728.1 - 0.42 11.0 7.1 0.72 10.2 4.0 2.6 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region DUF1840 PF08895.11 OEU06728.1 - 0.56 10.6 4.4 20 5.5 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF1635 PF07795.11 OEU06728.1 - 1.2 8.9 12.7 0.1 12.4 7.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) MAP17 PF15807.5 OEU06728.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.1 4 0 0 4 4 4 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SPG4 PF17325.2 OEU06730.1 - 0.0055 17.8 1.7 0.0055 17.8 1.7 3.8 3 1 1 4 4 4 1 Stationary phase protein 4 Heliorhodopsin PF18761.1 OEU06731.1 - 0.0023 17.3 1.6 0.0028 17.0 1.6 1.0 1 0 0 1 1 1 1 Heliorhodopsin HV_small_capsid PF17086.5 OEU06731.1 - 0.062 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Small capsid protein of Herpesviridae DUF5345 PF17280.2 OEU06731.1 - 0.063 13.3 0.2 0.099 12.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) PIG-Y PF15159.6 OEU06731.1 - 0.2 12.6 3.3 0.37 11.7 3.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Glutaredoxin PF00462.24 OEU06732.1 - 1.2e-13 51.0 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 OEU06732.1 - 0.00034 20.6 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU06732.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU06732.1 - 0.0013 19.0 0.1 0.0059 16.9 0.1 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 OEU06732.1 - 0.012 15.7 0.0 0.16 12.1 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.21 OEU06732.1 - 0.03 14.2 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 OEU06732.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 OEU06732.1 - 0.17 12.1 0.1 0.2 11.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like zf-RVT PF13966.6 OEU06733.1 - 0.0026 18.4 1.1 0.0026 18.4 1.1 3.0 3 2 1 4 4 4 1 zinc-binding in reverse transcriptase DUF3037 PF11236.8 OEU06733.1 - 0.52 10.8 2.4 0.42 11.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) PGM_PMM_II PF02879.16 OEU06734.1 - 0.12 13.0 0.0 0.28 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Sel1 PF08238.12 OEU06735.1 - 0.037 14.7 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Sel1 repeat Myb_DNA-binding PF00249.31 OEU06736.1 - 3.7e-11 43.0 0.1 2.3e-10 40.5 0.1 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF5580 PF17743.1 OEU06736.1 - 0.16 10.5 8.3 0.19 10.3 1.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5580) RbsD_FucU PF05025.13 OEU06736.1 - 1.1 9.7 3.7 3.9 7.9 0.8 2.4 1 1 1 2 2 2 0 RbsD / FucU transport protein family LAP1C PF05609.12 OEU06736.1 - 1.7 7.7 13.3 2 7.4 3.8 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) E7 PF00527.18 OEU06736.1 - 1.9 8.7 4.7 4.5 7.5 4.7 1.6 1 0 0 1 1 1 0 E7 protein, Early protein DUF4637 PF15470.6 OEU06736.1 - 4.9 6.9 11.2 0.3 10.8 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) GREB1 PF15782.5 OEU06736.1 - 7.1 3.6 9.2 9.5 3.2 9.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4271 PF14093.6 OEU06737.1 - 0.0052 16.7 7.8 0.016 15.1 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4271) NPR3 PF03666.13 OEU06737.1 - 0.0068 15.3 0.4 0.011 14.5 0.4 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 TMEM100 PF16311.5 OEU06737.1 - 0.092 12.3 1.1 0.24 11.0 0.1 2.1 2 1 0 2 2 2 0 Transmembrane protein 100 TrbC PF04956.13 OEU06737.1 - 0.28 11.4 3.9 4.6 7.5 4.6 2.7 3 0 0 3 3 3 0 TrbC/VIRB2 family CN_hydrolase PF00795.22 OEU06739.1 - 1.4e-29 103.2 0.0 2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 OEU06739.1 - 4.2e-22 78.5 0.0 1.9e-17 63.2 0.0 3.5 1 1 0 1 1 1 1 NAD synthase Mrr_N PF14338.6 OEU06741.1 - 0.0088 16.1 0.1 0.33 11.1 0.0 3.0 4 0 0 4 4 4 1 Mrr N-terminal domain HTH_27 PF13463.6 OEU06741.1 - 0.036 14.5 0.0 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HA PF03457.14 OEU06742.1 - 1.5e-73 243.0 15.5 3.8e-14 52.8 0.1 7.5 7 1 0 7 7 7 7 Helicase associated domain GT-D PF08759.11 OEU06742.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.9 4 0 0 4 4 4 0 Glycosyltransferase GT-D fold SSF PF00474.17 OEU06744.1 - 1.6e-07 30.6 14.5 2.1e-07 30.2 14.5 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Vut_1 PF02592.15 OEU06744.1 - 0.91 9.8 11.9 0.23 11.8 3.6 2.4 1 1 1 2 2 2 0 Putative vitamin uptake transporter SURF1 PF02104.15 OEU06745.1 - 5.9e-25 88.5 0.0 9.5e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 SURF1 family DUF3439 PF11921.8 OEU06746.1 - 0.073 13.0 6.1 0.23 11.4 6.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3654 PF12376.8 OEU06746.1 - 0.12 12.6 0.4 12 6.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) HMA PF00403.26 OEU06747.1 - 0.018 15.5 1.5 12 6.5 0.0 3.2 3 0 0 3 3 3 0 Heavy-metal-associated domain Serglycin PF04360.12 OEU06747.1 - 0.024 14.6 4.1 0.053 13.5 4.1 1.6 1 0 0 1 1 1 0 Serglycin FtsX PF02687.21 OEU06749.1 - 0.67 10.5 6.7 4.9 7.7 3.8 2.8 1 1 1 2 2 2 0 FtsX-like permease family Ctr PF04145.15 OEU06750.1 - 0.0054 17.4 1.1 0.014 16.0 0.5 1.9 2 0 0 2 2 2 1 Ctr copper transporter family Serinc PF03348.15 OEU06750.1 - 0.01 14.8 1.1 0.13 11.1 1.0 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Apt1 PF10351.9 OEU06750.1 - 0.016 14.1 3.2 0.022 13.6 3.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2973 PF11189.8 OEU06750.1 - 0.026 14.6 5.3 8.1 6.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) NPR3 PF03666.13 OEU06750.1 - 0.038 12.8 3.2 0.061 12.1 3.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TMEM154 PF15102.6 OEU06750.1 - 0.13 12.1 6.5 0.72 9.7 6.5 2.3 1 1 0 1 1 1 0 TMEM154 protein family SR-25 PF10500.9 OEU06750.1 - 0.17 11.5 13.8 0.27 10.8 13.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pol_alpha_B_N PF08418.10 OEU06750.1 - 0.2 11.6 10.0 0.34 10.8 10.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ABC2_membrane_3 PF12698.7 OEU06750.1 - 0.43 9.6 6.6 0.74 8.9 4.5 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein PMT_4TMC PF16192.5 OEU06750.1 - 0.49 9.9 2.0 0.62 9.6 0.8 1.7 1 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Orf78 PF06024.12 OEU06750.1 - 1.4 9.2 13.0 5.6 7.3 9.3 3.3 2 1 0 2 2 2 0 Orf78 (ac78) DUF1681 PF07933.14 OEU06753.1 - 2.7e-14 53.1 0.1 9.4e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1681) Macoilin PF09726.9 OEU06753.1 - 0.34 9.4 7.6 0.41 9.1 7.6 1.1 1 0 0 1 1 1 0 Macoilin family NST1 PF13945.6 OEU06753.1 - 3.3 7.8 13.7 6.1 6.9 13.7 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.13 OEU06753.1 - 7.2 4.8 8.8 10 4.4 8.8 1.2 1 0 0 1 1 1 0 Menin PT PF04886.12 OEU06754.1 - 6.7e-10 38.3 51.6 0.009 15.5 13.7 3.4 1 1 1 2 2 2 2 PT repeat Ge1_WD40 PF16529.5 OEU06755.1 - 1.9e-07 30.4 0.0 1.2e-06 27.8 0.0 2.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SPATIAL PF15256.6 OEU06755.1 - 0.012 15.9 2.1 0.028 14.8 2.1 1.6 1 0 0 1 1 1 0 SPATIAL SseC PF04888.12 OEU06755.1 - 0.042 13.5 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Spt20 PF12090.8 OEU06755.1 - 1.2 8.7 9.1 2.6 7.6 9.1 1.5 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 OEU06755.1 - 1.7 9.6 7.6 4.4 8.3 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat SDP_N PF12278.8 OEU06755.1 - 5.5 7.1 8.1 13 5.9 8.1 1.5 1 0 0 1 1 1 0 Sex determination protein N terminal Ndc1_Nup PF09531.10 OEU06755.1 - 6.4 5.3 8.8 11 4.5 8.8 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5478 PF17572.2 OEU06758.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5478) CDC27 PF09507.10 OEU06759.1 - 0.0032 16.9 14.6 0.0039 16.6 14.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 FdhE PF04216.12 OEU06759.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation TAF1D PF15333.6 OEU06759.1 - 1.2 8.9 13.1 1.7 8.3 13.1 1.4 1 1 0 1 1 1 0 TATA box-binding protein-associated factor 1D SMYLE_N PF18615.1 OEU06759.1 - 4.2 6.8 9.2 5.1 6.6 9.2 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Caprin-1_C PF12287.8 OEU06759.1 - 8.4 6.4 14.4 9.6 6.3 14.4 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DDE_Tnp_1_7 PF13843.6 OEU06760.1 - 7.4e-18 65.0 0.1 1.9e-17 63.6 0.1 1.6 1 1 0 1 1 1 1 Transposase IS4 HA PF03457.14 OEU06762.1 - 7.3e-17 61.5 0.2 7.1e-10 39.1 0.3 2.4 2 1 0 2 2 2 2 Helicase associated domain ISAV_HA PF06215.11 OEU06762.1 - 0.005 16.0 0.4 0.0072 15.5 0.4 1.2 1 0 0 1 1 1 1 Infectious salmon anaemia virus haemagglutinin Lactococcin_972 PF09683.10 OEU06763.1 - 0.039 14.5 0.7 0.13 12.8 0.7 1.9 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) DUF3348 PF11828.8 OEU06764.1 - 0.00045 20.0 0.1 20 4.8 0.0 5.1 5 1 1 6 6 6 1 Protein of unknown function (DUF3348) Gly-zipper_Omp PF13488.6 OEU06764.1 - 0.00097 19.1 59.4 0.013 15.5 2.3 8.5 2 2 8 10 10 10 6 Glycine zipper Rick_17kDa_Anti PF05433.15 OEU06764.1 - 0.0049 16.7 5.4 0.0049 16.7 5.4 9.0 6 3 3 9 9 9 6 Glycine zipper 2TM domain MccV PF17508.2 OEU06764.1 - 1.2 9.7 12.0 10 6.8 0.0 5.7 5 2 1 7 7 7 0 Microcin V bacteriocin Gly-zipper_YMGG PF13441.6 OEU06764.1 - 5.7 6.8 49.5 0.21 11.4 2.8 8.0 6 3 0 6 6 6 0 YMGG-like Gly-zipper Amastin PF07344.11 OEU06766.1 - 0.00035 20.5 1.3 0.0021 17.9 0.0 2.4 1 1 1 2 2 2 1 Amastin surface glycoprotein Tim54 PF11711.8 OEU06766.1 - 0.016 14.0 0.2 0.026 13.3 0.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Macoilin PF09726.9 OEU06766.1 - 3.9 5.9 9.1 5.7 5.4 9.1 1.2 1 0 0 1 1 1 0 Macoilin family PT PF04886.12 OEU06767.1 - 3.9e-05 23.1 77.2 9.4e-05 21.9 27.4 3.5 2 1 1 3 3 3 2 PT repeat GCV_T PF01571.21 OEU06768.1 - 3e-74 249.6 0.0 3.8e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OEU06768.1 - 1.4e-15 56.9 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Hydrolase PF00702.26 OEU06769.1 - 7.6e-17 62.3 0.0 1.2e-16 61.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OEU06769.1 - 4.2e-06 26.7 2.9 0.00057 19.7 0.3 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Yae1_N PF09811.9 OEU06770.1 - 0.0083 15.8 36.8 15 5.4 0.4 9.6 6 3 2 8 8 8 6 Essential protein Yae1, N terminal PT PF04886.12 OEU06771.1 - 4.4e-11 42.1 167.9 0.014 14.9 16.0 12.6 6 3 4 10 10 10 7 PT repeat GST_N_3 PF13417.6 OEU06773.1 - 0.00033 21.0 0.0 0.00045 20.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU06773.1 - 0.00037 20.8 0.0 0.00052 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU06773.1 - 0.0033 17.7 0.0 0.0044 17.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain She9_MDM33 PF05546.11 OEU06774.1 - 1.9e-25 89.9 4.0 1.9e-25 89.9 4.0 1.7 2 0 0 2 2 2 1 She9 / Mdm33 family SQHop_cyclase_C PF13243.6 OEU06774.1 - 0.0063 15.6 0.1 0.0083 15.3 0.1 1.2 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Rad60-SLD PF11976.8 OEU06775.1 - 2.7e-14 52.7 0.0 3.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OEU06775.1 - 5.5e-07 29.3 0.0 7.6e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family CNTF PF01110.17 OEU06775.1 - 0.062 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor RRM_1 PF00076.22 OEU06776.1 - 0.0015 18.3 0.2 0.0052 16.6 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CUT PF02376.15 OEU06778.1 - 0.031 14.5 0.1 0.069 13.3 0.1 1.6 1 0 0 1 1 1 0 CUT domain HA PF03457.14 OEU06779.1 - 0.12 12.7 0.2 7.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Helicase associated domain GBP PF02263.19 OEU06780.1 - 1.5e-51 175.2 0.8 2e-51 174.8 0.8 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OEU06780.1 - 6.5e-05 22.5 0.3 6.5e-05 22.5 0.3 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain DUF3993 PF13158.6 OEU06780.1 - 0.038 14.2 0.8 0.22 11.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3993) DUF4145 PF13643.6 OEU06780.1 - 0.061 13.4 0.1 0.46 10.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) zf-trcl PF13451.6 OEU06781.1 - 2e-09 37.2 0.7 2e-09 37.2 0.7 3.4 4 0 0 4 4 4 2 Probable zinc-ribbon domain MacB_PCD PF12704.7 OEU06783.1 - 0.24 11.7 0.0 0.29 11.5 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain Aldolase_II PF00596.21 OEU06784.1 - 3.1e-31 108.8 0.0 7.4e-31 107.5 0.0 1.7 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.19 OEU06784.1 - 6e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PT PF04886.12 OEU06785.1 - 3e-05 23.5 10.5 0.0016 17.9 10.5 2.8 1 1 0 1 1 1 1 PT repeat FAD_syn PF06574.12 OEU06788.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase CTP_transf_like PF01467.26 OEU06788.1 - 0.01 16.1 0.0 0.035 14.3 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF1275 PF06912.11 OEU06788.1 - 0.23 11.3 2.8 0.35 10.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF3899 PF13038.6 OEU06788.1 - 3.5 8.2 0.0 3.5 8.2 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3899) DUF3082 PF11282.8 OEU06789.1 - 1e-17 64.2 4.5 1.4e-17 63.7 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) FAM176 PF14851.6 OEU06794.1 - 0.016 14.9 0.4 0.016 14.9 0.4 2.6 2 1 1 3 3 3 0 FAM176 family FPP PF05911.11 OEU06797.1 - 1.5 6.9 5.2 1.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1120 PF06551.12 OEU06798.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) F-box-like PF12937.7 OEU06799.1 - 0.03 14.2 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like DNA_pol_phi PF04931.13 OEU06800.1 - 0.8 7.7 5.9 0.97 7.5 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi COX4 PF02936.14 OEU06802.1 - 0.0048 16.9 1.4 1.4 8.9 0.0 2.6 2 1 1 3 3 3 2 Cytochrome c oxidase subunit IV zf-RING_2 PF13639.6 OEU06803.1 - 1.9e-13 50.5 7.3 2.1e-13 50.4 7.3 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU06803.1 - 4.6e-13 48.7 2.2 7.4e-13 48.0 2.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU06803.1 - 5.2e-11 42.2 6.8 6.3e-11 41.9 6.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU06803.1 - 2.1e-09 37.1 4.9 2.6e-09 36.8 4.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU06803.1 - 3.6e-08 33.6 10.4 3.7e-07 30.3 10.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU06803.1 - 2.4e-07 30.6 1.9 2.4e-07 30.6 1.9 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU06803.1 - 3.4e-06 26.9 4.9 4e-06 26.7 4.9 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU06803.1 - 3.7e-05 23.5 3.5 4.3e-05 23.3 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU06803.1 - 6.3e-05 23.0 5.3 9.8e-05 22.3 5.3 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OEU06803.1 - 0.0018 18.0 5.7 0.0024 17.6 5.7 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 OEU06803.1 - 0.0022 17.9 1.5 0.0022 17.9 1.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 OEU06803.1 - 0.0046 16.5 4.6 0.0072 15.9 4.6 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OEU06803.1 - 0.0054 16.6 5.4 0.0072 16.2 5.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OEU06803.1 - 0.011 15.9 6.9 0.057 13.6 6.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OEU06803.1 - 0.018 15.1 4.4 0.048 13.8 4.4 1.6 1 1 0 1 1 1 0 RING-variant domain zf-UDP PF14569.6 OEU06803.1 - 0.028 14.5 2.9 0.041 14.0 2.9 1.3 1 1 0 1 1 1 0 Zinc-binding RING-finger FANCL_C PF11793.8 OEU06803.1 - 0.031 14.4 8.4 0.9 9.8 8.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 OEU06803.1 - 0.035 14.0 5.8 0.061 13.2 5.8 1.5 1 1 0 1 1 1 0 PHD-finger Rad50_zn_hook PF04423.14 OEU06803.1 - 0.065 13.1 0.5 0.065 13.1 0.5 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif Zf_RING PF16744.5 OEU06803.1 - 0.081 13.1 2.4 0.13 12.4 2.4 1.4 1 1 0 1 1 1 0 KIAA1045 RING finger zf-Nse PF11789.8 OEU06803.1 - 0.13 12.1 2.6 0.16 11.8 2.6 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit MutS_III PF05192.18 OEU06805.1 - 2.4e-20 73.5 8.7 5.7e-20 72.3 8.7 1.7 1 0 0 1 1 1 1 MutS domain III Tombus_P33 PF08500.10 OEU06805.1 - 0.027 14.4 4.7 1.4 8.9 1.3 3.0 2 1 1 3 3 3 0 Tombusvirus p33 TFIIA PF03153.13 OEU06805.1 - 0.38 10.7 11.8 0.067 13.2 5.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1840 PF08895.11 OEU06805.1 - 7.5 6.9 7.7 4.1 7.8 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) EST1 PF10374.9 OEU06806.1 - 0.038 14.6 0.0 0.064 13.9 0.0 1.3 1 0 0 1 1 1 0 Telomerase activating protein Est1 PgaD PF13994.6 OEU06806.1 - 0.062 13.4 5.5 0.17 12.0 1.9 2.4 2 0 0 2 2 2 0 PgaD-like protein DUF4834 PF16118.5 OEU06806.1 - 0.91 10.5 7.0 4.9 8.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) PT PF04886.12 OEU06807.1 - 7.2e-07 28.6 18.3 0.012 15.2 18.3 2.6 1 1 0 1 1 1 1 PT repeat Neisseria_TspB PF05616.13 OEU06807.1 - 5.9 5.2 5.9 5.3 5.4 5.9 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SLC12 PF03522.15 OEU06808.1 - 3.3 6.7 6.1 6.1 5.7 6.1 1.5 1 0 0 1 1 1 0 Solute carrier family 12 DUF4748 PF15932.5 OEU06812.1 - 0.031 14.0 0.3 0.072 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Evr1_Alr PF04777.13 OEU06812.1 - 0.067 13.7 0.5 0.067 13.7 0.5 2.1 2 1 0 2 2 2 0 Erv1 / Alr family Tir_receptor_C PF07489.11 OEU06812.1 - 0.47 10.4 11.1 0.77 9.7 11.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Sigma70_ner PF04546.13 OEU06813.1 - 0.39 10.6 5.3 0.29 11.0 3.7 1.5 1 1 1 2 2 2 0 Sigma-70, non-essential region Vps62 PF06101.11 OEU06814.1 - 0.031 12.6 0.0 0.042 12.2 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 Imm5 PF14423.6 OEU06815.1 - 1.3 9.2 4.5 0.51 10.5 1.6 1.8 2 0 0 2 2 2 0 Immunity protein Imm5 ACPS PF01648.20 OEU06816.1 - 6.7e-11 42.3 0.2 2.1e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Thioredoxin PF00085.20 OEU06818.1 - 1.6e-23 82.7 0.2 2.4e-23 82.1 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU06818.1 - 1e-05 25.9 0.0 9.6e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU06818.1 - 3e-05 24.3 0.9 0.0017 18.6 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 OEU06818.1 - 9.6e-05 22.2 0.1 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OEU06818.1 - 0.0062 16.4 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU06818.1 - 0.0096 15.6 0.1 0.017 14.9 0.0 1.5 2 0 0 2 2 2 1 Redoxin Peptidase_M24 PF00557.24 OEU06818.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 Thioredoxin_7 PF13899.6 OEU06818.1 - 0.014 15.6 0.0 0.045 13.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like TraF PF13728.6 OEU06818.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HC2 PF07382.11 OEU06819.1 - 4.7 7.2 61.6 6.9 6.7 61.6 1.3 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ABC_membrane PF00664.23 OEU06820.1 - 8.2e-30 104.4 5.3 1.4e-29 103.6 5.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2892 PF11127.8 OEU06820.1 - 1.4 9.1 5.6 0.23 11.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF4191 PF13829.6 OEU06820.1 - 3.5 6.9 4.1 2.4 7.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF285 PF03382.14 OEU06822.1 - 7.1e-55 184.0 17.5 2.7e-29 101.4 8.9 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 RRM_1 PF00076.22 OEU06823.1 - 8.5e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OEU06823.1 - 0.0019 19.2 0.0 0.0026 18.8 0.0 1.2 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein DUF1866 PF08952.11 OEU06823.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Herpes_TAF50 PF03326.13 OEU06826.1 - 0.94 8.1 6.2 1.8 7.1 6.2 1.4 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Spc7 PF08317.11 OEU06829.1 - 0.002 17.1 14.1 0.082 11.8 4.6 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF713 PF05218.14 OEU06829.1 - 0.0058 16.4 3.1 0.029 14.1 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF713) FliJ PF02050.16 OEU06829.1 - 0.046 14.0 1.0 0.14 12.4 0.4 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Filament PF00038.21 OEU06829.1 - 0.049 13.2 13.3 0.3 10.6 3.6 2.8 1 1 0 2 2 2 0 Intermediate filament protein TMPIT PF07851.13 OEU06829.1 - 0.19 10.9 9.1 0.16 11.2 2.5 2.3 2 0 0 2 2 2 0 TMPIT-like protein Prefoldin_2 PF01920.20 OEU06829.1 - 0.29 11.1 11.1 0.38 10.7 2.7 3.6 1 1 2 3 3 3 0 Prefoldin subunit SlyX PF04102.12 OEU06829.1 - 0.37 11.4 2.5 0.68 10.6 0.4 2.5 2 0 0 2 2 2 0 SlyX GTP-bdg_M PF16360.5 OEU06829.1 - 0.38 11.4 2.8 5.4 7.7 0.3 3.4 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region DHR10 PF18595.1 OEU06829.1 - 0.42 10.7 13.2 3.6 7.7 1.7 3.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 OEU06829.1 - 0.45 10.8 12.7 6.6 7.0 4.9 2.8 1 1 1 2 2 2 0 Tho complex subunit 7 DUF5082 PF16888.5 OEU06829.1 - 0.73 10.1 13.0 60 3.9 1.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF641 PF04859.12 OEU06829.1 - 1.3 9.4 8.0 0.55 10.6 1.2 2.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 OEU06829.1 - 5.3 6.0 14.4 0.82 8.7 3.9 2.4 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 OEU06829.1 - 5.8 7.4 17.2 2 8.9 0.5 5.1 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 OEU06829.1 - 9.6 6.3 14.8 0.27 11.3 0.3 3.4 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SpoU_methylas_C PF12105.8 OEU06830.1 - 0.049 13.3 1.2 0.094 12.4 1.2 1.5 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal RRM_1 PF00076.22 OEU06831.1 - 8.8e-46 153.6 0.1 4.4e-19 68.1 0.1 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU06831.1 - 3.8e-06 26.5 0.1 0.0019 17.8 0.0 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OEU06831.1 - 0.0015 18.5 0.1 0.044 13.8 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OEU06831.1 - 0.003 17.7 0.0 2.3 8.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif NOP5NT PF08156.13 OEU06831.1 - 0.0049 17.2 1.0 5.1 7.6 0.1 3.1 3 0 0 3 3 3 2 NOP5NT (NUC127) domain Limkain-b1 PF11608.8 OEU06831.1 - 0.015 15.4 0.0 1.9 8.7 0.0 2.7 1 1 1 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 OEU06831.1 - 0.02 15.1 0.5 8.8 6.5 0.1 3.7 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 OEU06831.1 - 0.026 14.4 0.1 9.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif SH3_1 PF00018.28 OEU06835.1 - 0.16 11.6 0.5 3 7.5 0.1 2.4 2 0 0 2 2 2 0 SH3 domain DDE_Tnp_1_7 PF13843.6 OEU06836.1 - 6.3e-10 38.9 0.0 9.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 AAA PF00004.29 OEU06840.1 - 7e-90 298.3 0.0 3.5e-46 156.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU06840.1 - 3.5e-25 87.5 7.1 3.5e-12 45.9 0.1 3.5 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 OEU06840.1 - 5.8e-15 55.8 0.1 6.7e-09 36.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OEU06840.1 - 4.1e-14 53.3 2.2 8.6e-06 26.2 0.1 4.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 OEU06840.1 - 8.3e-14 51.8 0.0 2.6e-08 34.0 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU06840.1 - 1.3e-12 47.7 0.0 2e-05 24.4 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OEU06840.1 - 4.2e-10 39.9 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 OEU06840.1 - 5.5e-10 39.0 0.0 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OEU06840.1 - 1.8e-09 38.0 0.6 0.037 14.3 0.1 4.2 2 2 0 3 3 3 2 AAA domain AAA_14 PF13173.6 OEU06840.1 - 3e-08 33.8 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OEU06840.1 - 7.5e-08 33.0 0.0 0.011 16.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OEU06840.1 - 2.7e-07 31.2 0.1 0.0048 17.4 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RNA_helicase PF00910.22 OEU06840.1 - 3.1e-07 30.7 0.0 0.0088 16.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.26 OEU06840.1 - 4.2e-07 29.8 0.0 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OEU06840.1 - 4.8e-07 29.8 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 OEU06840.1 - 5.5e-07 29.5 0.2 0.021 14.5 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 OEU06840.1 - 6e-07 29.6 0.1 0.053 13.4 0.0 2.7 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_28 PF13521.6 OEU06840.1 - 1.4e-06 28.7 0.0 0.094 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 OEU06840.1 - 2.8e-06 26.9 0.5 1.4 8.2 0.0 3.4 2 1 1 3 3 3 2 KaiC TsaE PF02367.17 OEU06840.1 - 4.5e-06 26.7 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OEU06840.1 - 4.9e-06 26.1 0.2 0.0079 15.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OEU06840.1 - 1.1e-05 25.1 0.1 0.2 11.2 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 OEU06840.1 - 1.1e-05 25.4 0.3 0.21 11.5 0.0 3.3 3 1 0 3 3 3 2 NACHT domain AAA_25 PF13481.6 OEU06840.1 - 1.2e-05 25.0 2.3 0.94 9.0 0.0 3.5 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 OEU06840.1 - 3.5e-05 23.8 5.2 0.25 11.2 0.0 3.8 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea CDC48_2 PF02933.17 OEU06840.1 - 8.3e-05 22.3 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_24 PF13479.6 OEU06840.1 - 9e-05 22.3 0.0 0.69 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OEU06840.1 - 9.4e-05 21.8 0.0 0.28 10.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.6 OEU06840.1 - 9.5e-05 22.8 0.0 0.075 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OEU06840.1 - 0.00026 20.5 0.1 0.74 9.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 OEU06840.1 - 0.00042 20.5 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.10 OEU06840.1 - 0.00047 20.1 0.1 0.002 18.1 0.1 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Cytidylate_kin2 PF13189.6 OEU06840.1 - 0.00053 20.2 0.1 0.99 9.5 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase-like family DUF815 PF05673.13 OEU06840.1 - 0.00055 19.2 0.0 0.58 9.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 OEU06840.1 - 0.0006 19.0 0.3 0.052 12.6 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 OEU06840.1 - 0.00076 18.7 0.0 0.3 10.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.9 OEU06840.1 - 0.00082 19.1 0.0 2.3 7.9 0.0 2.8 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 OEU06840.1 - 0.00084 19.9 0.4 2.8 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain TMEM156 PF15106.6 OEU06840.1 - 0.003 17.0 0.2 0.0049 16.3 0.2 1.2 1 0 0 1 1 1 1 TMEM156 protein family AAA_29 PF13555.6 OEU06840.1 - 0.0035 17.1 0.0 0.52 10.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SKI PF01202.22 OEU06840.1 - 0.0043 17.2 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Bac_DnaA PF00308.18 OEU06840.1 - 0.0073 16.2 0.0 0.98 9.2 0.0 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 OEU06840.1 - 0.0085 15.9 0.7 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 OEU06840.1 - 0.0088 15.8 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_3 PF07726.11 OEU06840.1 - 0.0094 15.8 0.0 2.1 8.2 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IPT PF01745.16 OEU06840.1 - 0.023 14.1 0.3 2.7 7.3 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 OEU06840.1 - 0.032 14.0 0.3 5.8 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OEU06840.1 - 0.034 14.1 0.0 2.9 7.9 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Enolase_like_N PF18374.1 OEU06840.1 - 0.053 12.9 0.6 10 5.6 0.0 3.6 4 0 0 4 4 3 0 Enolase N-terminal domain-like NTPase_1 PF03266.15 OEU06840.1 - 0.075 12.9 3.0 5.1 7.0 0.1 3.7 3 1 2 5 5 4 0 NTPase AAA_6 PF12774.7 OEU06840.1 - 0.089 11.7 0.1 0.94 8.4 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region TniB PF05621.11 OEU06840.1 - 0.14 11.6 0.0 23 4.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 OEU06840.1 - 0.38 11.1 4.1 17 5.7 0.0 3.3 3 1 1 4 4 2 0 AAA domain FAM176 PF14851.6 OEU06840.1 - 0.68 9.6 4.3 1.2 8.8 4.3 1.4 1 0 0 1 1 1 0 FAM176 family DHQ_synthase PF01761.20 OEU06841.1 - 4.1e-105 350.7 0.0 5.3e-105 350.3 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OEU06841.1 - 1.6e-11 44.4 0.2 1.1e-10 41.6 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 OEU06841.1 - 6.4e-09 35.1 0.3 1.4e-08 33.9 0.3 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Endopep_inhib PF16800.5 OEU06841.1 - 0.058 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor DUF3134 PF11332.8 OEU06841.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Xan_ur_permease PF00860.20 OEU06842.1 - 1.4e-68 231.4 28.1 2.6e-48 164.6 9.2 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 OEU06842.1 - 2.2e-08 33.2 2.3 4.7e-08 32.2 2.3 1.5 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 OEU06842.1 - 0.00015 22.1 1.3 0.00015 22.1 1.3 3.1 2 1 1 3 3 3 1 Molybdate transporter of MFS superfamily DUF2157 PF09925.9 OEU06842.1 - 6.4 6.6 8.8 0.79 9.5 3.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Xan_ur_permease PF00860.20 OEU06843.1 - 1.4e-68 231.4 28.1 2.6e-48 164.6 9.2 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 OEU06843.1 - 2.2e-08 33.2 2.3 4.7e-08 32.2 2.3 1.5 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 OEU06843.1 - 0.00015 22.1 1.3 0.00015 22.1 1.3 3.1 2 1 1 3 3 3 1 Molybdate transporter of MFS superfamily DUF2157 PF09925.9 OEU06843.1 - 6.4 6.6 8.8 0.79 9.5 3.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) VASt PF16016.5 OEU06845.1 - 1.2e-10 42.0 0.1 4.8e-10 40.0 0.1 2.1 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF5611 PF18446.1 OEU06845.1 - 9 7.2 9.9 0.2 12.5 0.4 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5611) adh_short PF00106.25 OEU06848.1 - 1.4e-31 109.5 2.1 1.8e-17 63.4 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU06848.1 - 4.6e-21 75.5 0.2 4.1e-11 42.9 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU06848.1 - 1.5e-07 31.5 0.0 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF285 PF03382.14 OEU06849.1 - 1.2e-54 183.2 19.6 1.9e-37 127.7 11.5 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 FAM176 PF14851.6 OEU06851.1 - 0.0012 18.5 1.1 0.0012 18.5 1.1 1.7 2 0 0 2 2 2 1 FAM176 family FAM60A PF15396.6 OEU06851.1 - 0.12 12.3 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TFB6 PF17110.5 OEU06851.1 - 0.2 11.4 2.1 0.41 10.4 2.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TipE PF16972.5 OEU06851.1 - 0.54 9.4 5.4 0.65 9.1 5.4 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF2457 PF10446.9 OEU06851.1 - 2.7 7.0 16.4 3.5 6.7 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 OEU06851.1 - 3.2 8.2 14.5 5.7 7.4 14.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.16 OEU06851.1 - 3.3 6.8 6.7 0.25 10.5 0.9 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2076 PF09849.9 OEU06851.1 - 7.8 6.5 9.2 12 5.9 9.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRN3 PF05327.11 OEU06851.1 - 8 4.9 6.5 11 4.4 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDE_Tnp_1_7 PF13843.6 OEU06853.1 - 0.00042 19.7 0.1 0.00047 19.6 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF4333 PF14230.6 OEU06853.1 - 0.054 13.7 0.5 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4333) IFRD PF05004.13 OEU06854.1 - 0.063 12.4 3.3 0.11 11.6 3.3 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) AF-4 PF05110.13 OEU06854.1 - 1.4 6.9 9.6 1.7 6.7 9.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3494 PF11999.8 OEU06855.1 - 1.9e-34 119.2 12.2 6.6e-34 117.4 12.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) HYR PF02494.16 OEU06855.1 - 4.6e-08 33.3 2.5 1.3e-07 31.8 2.5 1.8 1 0 0 1 1 1 1 HYR domain RNA_capsid PF03035.14 OEU06856.1 - 0.7 9.9 4.2 0.59 10.1 2.4 1.7 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein FtsX PF02687.21 OEU06858.1 - 0.0024 18.3 2.5 0.0024 18.3 2.5 2.4 1 1 0 2 2 2 1 FtsX-like permease family Tetraspanin PF00335.20 OEU06858.1 - 0.01 15.6 9.5 0.015 15.1 9.5 1.2 1 0 0 1 1 1 0 Tetraspanin family TssN PF17555.2 OEU06858.1 - 0.018 14.4 2.5 0.026 13.9 2.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN Sm_multidrug_ex PF06695.11 OEU06858.1 - 0.095 13.3 0.9 0.095 13.3 0.9 2.5 2 1 1 3 3 3 0 Putative small multi-drug export protein ADP_ribosyl_GH PF03747.14 OEU06858.1 - 1.3 8.7 3.2 1.5 8.5 3.2 1.3 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4064 PF13273.6 OEU06858.1 - 3.6 7.9 16.5 0.37 11.1 8.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) PhyH PF05721.13 OEU06859.1 - 2.1e-11 44.5 0.8 6.1e-10 39.7 0.4 2.6 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Herpes_TAF50 PF03326.13 OEU06862.1 - 1.2 7.7 5.9 2.4 6.7 5.9 1.4 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4174 PF13778.6 OEU06863.1 - 0.085 13.3 1.4 0.19 12.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) BTB_2 PF02214.22 OEU06864.1 - 9e-18 64.4 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU06864.1 - 6.2e-05 23.1 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TENA_THI-4 PF03070.16 OEU06865.1 - 7.5e-28 97.8 0.7 9.7e-28 97.4 0.7 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PLAC8 PF04749.17 OEU06866.1 - 0.032 15.2 13.3 0.054 14.5 13.3 1.5 1 1 0 1 1 1 0 PLAC8 family Flavin_Reduct PF01613.18 OEU06867.1 - 1.6e-06 28.3 0.0 2.9e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 OEU06867.1 - 0.022 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF447) zf-MYND PF01753.18 OEU06870.1 - 1.9e-09 37.4 9.2 3.4e-09 36.7 9.2 1.4 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 OEU06870.1 - 2.6 8.5 9.1 1.2 9.5 6.7 1.7 2 0 0 2 2 2 0 Rhodanase C-terminal TLD PF07534.16 OEU06871.1 - 9.4e-13 48.6 6.7 2.6e-10 40.6 0.2 2.7 3 0 0 3 3 3 2 TLD TUSC2 PF15000.6 OEU06871.1 - 0.77 10.1 0.0 0.77 10.1 0.0 2.7 3 1 0 3 3 3 0 Tumour suppressor candidate 2 SET PF00856.28 OEU06873.1 - 1.7e-06 28.5 0.2 0.00012 22.5 0.0 3.3 2 1 0 2 2 2 1 SET domain TackOD1 PF18551.1 OEU06873.1 - 0.035 13.8 0.1 0.1 12.2 0.1 1.8 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 F-box-like PF12937.7 OEU06874.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like TMEM132D_N PF15705.5 OEU06874.1 - 0.12 12.2 0.0 0.47 10.3 0.0 1.9 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term DUF4502 PF14950.6 OEU06874.1 - 0.38 10.1 3.4 0.53 9.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) GEN1_C PF18380.1 OEU06874.1 - 2.2 9.2 5.1 2.4 9.1 3.7 1.7 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DNA_pol_phi PF04931.13 OEU06874.1 - 3.7 5.5 6.8 5.8 4.9 6.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi CN_hydrolase PF00795.22 OEU06877.1 - 5.7e-05 22.6 0.0 0.00019 20.8 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase PAS_9 PF13426.7 OEU06878.1 - 1e-15 57.8 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 OEU06878.1 - 0.00015 21.8 7.4 0.00025 21.0 7.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OEU06878.1 - 0.00034 20.6 8.7 0.00063 19.8 8.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 OEU06878.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OEU06878.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold IATP PF04568.12 OEU06878.1 - 0.089 13.2 1.8 0.22 12.0 1.8 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PAS_8 PF13188.7 OEU06878.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF3494 PF11999.8 OEU06879.1 - 1.3e-58 198.1 11.7 1.6e-58 197.8 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Pirin PF02678.16 OEU06880.1 - 2.5e-09 37.1 0.8 2.9e-06 27.2 0.8 3.0 1 1 0 1 1 1 1 Pirin Pirin_C PF05726.13 OEU06880.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Pirin C-terminal cupin domain GCFC PF07842.12 OEU06881.1 - 4.8e-08 32.9 7.7 3.9e-05 23.4 1.5 3.6 2 1 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 OEU06881.1 - 1.4e-05 25.4 10.4 1.4e-05 25.4 10.4 5.9 4 1 2 6 6 6 1 Tuftelin interacting protein N terminal Ion_trans_2 PF07885.16 OEU06882.1 - 2.2e-06 27.6 11.0 5.2e-06 26.3 11.0 1.7 1 1 0 1 1 1 1 Ion channel IRK_C PF17655.1 OEU06882.1 - 0.0013 18.3 0.0 0.48 10.0 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OEU06882.1 - 0.0047 16.7 9.2 0.034 14.0 9.2 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain zf-MYND PF01753.18 OEU06883.1 - 1.2e-06 28.5 9.9 1.2e-06 28.5 9.9 4.7 3 2 0 3 3 3 1 MYND finger CorA PF01544.18 OEU06885.1 - 0.00024 20.5 0.9 0.00024 20.5 0.9 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EF-hand_8 PF13833.6 OEU06885.1 - 0.011 15.6 2.3 0.1 12.5 2.3 2.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 OEU06885.1 - 0.046 14.2 1.4 0.15 12.5 1.2 1.9 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 OEU06885.1 - 0.09 12.4 0.2 0.37 10.5 0.2 2.1 1 0 0 1 1 1 0 EF hand DUF4834 PF16118.5 OEU06885.1 - 1.2 10.1 11.6 1.1 10.3 2.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 OEU06886.1 - 0.34 10.5 10.3 0.55 9.8 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein cobW PF02492.19 OEU06887.1 - 5.6e-43 146.6 1.0 7.7e-43 146.1 1.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU06887.1 - 3.6e-16 58.9 0.0 9.6e-16 57.5 0.0 1.8 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 OEU06887.1 - 0.0025 17.7 0.0 0.0065 16.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 OEU06887.1 - 0.0075 16.8 1.3 0.016 15.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OEU06887.1 - 0.02 14.6 0.4 0.058 13.1 0.1 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 OEU06887.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OEU06887.1 - 0.18 12.1 0.1 0.4 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF2470 PF10615.9 OEU06888.1 - 1.9e-10 41.2 0.2 1.1e-09 38.8 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2470) 7TM_GPCR_Srv PF10323.9 OEU06888.1 - 0.018 14.4 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv ETRAMP PF09716.10 OEU06888.1 - 0.25 11.4 3.3 0.9 9.6 3.3 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1699 PF08004.11 OEU06889.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Epimerase PF01370.21 OEU06890.1 - 3.9e-07 29.8 0.0 6.1e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OEU06890.1 - 3.7e-05 23.7 0.0 0.034 14.1 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OEU06890.1 - 0.0006 18.9 0.7 0.0023 17.0 0.7 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACT PF01842.25 OEU06890.1 - 0.001 18.8 0.1 0.0036 17.0 0.0 1.9 1 1 1 2 2 2 1 ACT domain GDP_Man_Dehyd PF16363.5 OEU06890.1 - 0.011 15.2 0.1 0.019 14.4 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OEU06890.1 - 0.032 13.8 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family AlaDh_PNT_C PF01262.21 OEU06890.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DXP_reductoisom PF02670.16 OEU06890.1 - 0.1 13.3 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Peptidase_S28 PF05577.12 OEU06892.1 - 4e-48 164.3 0.1 5.7e-48 163.8 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Fasciclin PF02469.22 OEU06893.1 - 2.5e-14 53.6 0.2 9.4e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Fasciclin domain Imm7 PF15585.6 OEU06893.1 - 0.02 15.2 1.3 0.048 13.9 1.3 1.6 1 0 0 1 1 1 0 Immunity protein 7 AAA_23 PF13476.6 OEU06893.1 - 0.03 14.8 3.1 0.053 14.0 3.1 1.4 1 0 0 1 1 1 0 AAA domain DAG_kinase_N PF14513.6 OEU06893.1 - 0.33 11.1 5.0 0.51 10.5 3.9 1.9 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus LCD1 PF09798.9 OEU06893.1 - 0.44 9.0 4.4 0.5 8.8 4.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein GrpE PF01025.19 OEU06893.1 - 0.44 10.2 9.0 0.68 9.6 9.0 1.3 1 0 0 1 1 1 0 GrpE DUF4407 PF14362.6 OEU06893.1 - 2.1 7.6 11.9 2.9 7.2 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCU PF04678.13 OEU06893.1 - 6.1 6.9 8.2 7.9 6.5 7.2 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter adh_short PF00106.25 OEU06894.1 - 6.9e-31 107.2 0.6 9.1e-31 106.8 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU06894.1 - 1.3e-18 67.4 0.1 1.8e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU06894.1 - 7.1e-16 58.6 0.5 1.2e-15 57.9 0.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU06894.1 - 0.0014 18.1 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OEU06894.1 - 0.19 11.5 1.4 11 5.9 0.2 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SURF4 PF02077.15 OEU06895.1 - 5.9e-19 68.7 14.6 3.5e-14 53.0 10.9 2.7 1 1 1 2 2 2 2 SURF4 family DoxX PF07681.12 OEU06895.1 - 0.00022 21.7 15.6 0.0013 19.2 5.6 2.7 2 0 0 2 2 2 2 DoxX TMEM101 PF15111.6 OEU06895.1 - 0.077 12.5 5.1 0.088 12.4 4.5 1.3 1 1 0 1 1 1 0 TMEM101 protein family NPF PF16601.5 OEU06896.1 - 0.0005 20.6 2.9 0.00067 20.2 2.9 1.2 1 0 0 1 1 1 1 Rabosyn-5 repeating NPF sequence-motif Copper-bind PF00127.20 OEU06897.1 - 5.8e-29 100.5 0.2 3.3e-28 98.0 0.1 2.0 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 OEU06897.1 - 8e-07 29.1 0.0 2.1e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Cupredoxin-like domain FOLN PF09289.10 OEU06897.1 - 0.084 13.1 1.9 0.085 13.1 0.2 1.9 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain Cofac_haem_bdg PF04187.13 OEU06898.1 - 2.1e-35 122.7 0.0 8.1e-35 120.8 0.0 1.8 1 1 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN FKBP_C PF00254.28 OEU06899.1 - 3.8e-07 30.3 0.0 1.1e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MaoC_dehydratas PF01575.19 OEU06899.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 2 0 0 2 2 2 0 MaoC like domain CRAL_TRIO PF00650.20 OEU06900.1 - 0.0055 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Mac PF12464.8 OEU06900.1 - 8.7 6.7 6.8 23 5.3 0.2 3.2 3 0 0 3 3 3 0 Maltose acetyltransferase DSPc PF00782.20 OEU06902.1 - 3.5e-11 43.1 0.1 6.7e-10 38.9 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain zf-PHD-like PF15446.6 OEU06902.1 - 0.082 12.5 0.2 0.24 11.0 0.2 1.8 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF2207 PF09972.9 OEU06903.1 - 0.022 13.6 0.0 0.023 13.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Oxidored_FMN PF00724.20 OEU06904.1 - 1.3e-58 198.9 0.0 2.8e-58 197.8 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 OEU06904.1 - 4.3e-13 49.1 0.0 7.2e-11 41.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU06904.1 - 0.0018 18.4 0.0 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU06904.1 - 0.017 15.7 0.1 11 6.7 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Voltage_CLC PF00654.20 OEU06905.1 - 3.9e-72 243.4 12.5 3.9e-72 243.4 12.5 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OEU06905.1 - 1.3e-13 51.1 0.5 1.2e-08 35.3 0.1 2.5 2 0 0 2 2 2 2 CBS domain SDA1 PF05285.12 OEU06905.1 - 0.48 9.8 10.2 0.71 9.2 10.2 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 OEU06906.1 - 1.7 9.1 6.9 2.1 8.8 6.2 1.5 1 1 0 1 1 1 0 Centromere protein B dimerisation domain HA PF03457.14 OEU06907.1 - 8.1e-28 96.6 0.7 1.7e-14 53.9 0.0 2.9 2 1 0 2 2 2 2 Helicase associated domain TT_ORF1 PF02956.14 OEU06908.1 - 0.0041 15.9 3.4 0.0041 15.9 3.4 1.7 2 0 0 2 2 2 1 TT viral orf 1 Shisa PF13908.6 OEU06908.1 - 0.0059 16.9 13.7 0.02 15.1 0.0 2.7 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator Claudin_2 PF13903.6 OEU06908.1 - 0.016 14.9 0.2 0.038 13.7 0.2 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Circo_capsid PF02443.15 OEU06908.1 - 0.49 9.9 8.0 0.84 9.2 8.0 1.3 1 0 0 1 1 1 0 Circovirus capsid protein ABC2_membrane_3 PF12698.7 OEU06908.1 - 0.7 8.9 4.8 0.93 8.5 0.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4551 PF15087.6 OEU06908.1 - 1.2 7.9 14.7 1.7 7.4 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 OEU06908.1 - 1.5 7.3 11.0 2.2 6.7 11.0 1.3 1 0 0 1 1 1 0 Macoilin family DUF4713 PF15831.5 OEU06908.1 - 3.3 8.2 14.2 5.7 7.5 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) CDC45 PF02724.14 OEU06908.1 - 4.6 5.4 10.5 6.9 4.8 10.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF5340 PF17275.2 OEU06909.1 - 0.43 10.7 6.5 13 6.0 0.8 4.0 2 0 0 2 2 2 0 Family of unknown function (DUF5340) DASH_Dam1 PF08653.10 OEU06909.1 - 0.46 10.3 2.6 1.7 8.5 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 SR-25 PF10500.9 OEU06910.1 - 0.21 11.2 9.7 7.3 6.1 6.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CNDH2_C PF16858.5 OEU06910.1 - 4 7.2 8.5 4.4 7.1 7.2 1.6 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Ureide_permease PF07168.11 OEU06911.1 - 3.8 6.2 6.7 0.16 10.7 0.4 1.7 2 0 0 2 2 2 0 Ureide permease Mito_fiss_reg PF05308.11 OEU06912.1 - 0.73 9.9 3.3 1.2 9.2 3.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SOG2 PF10428.9 OEU06912.1 - 3.3 6.8 11.0 4.3 6.4 11.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Polyketide_cyc2 PF10604.9 OEU06913.1 - 0.22 11.8 0.9 0.39 11.0 0.9 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport potato_inhibit PF00280.18 OEU06914.1 - 1.3e-13 51.4 0.0 3.9e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 Potato inhibitor I family DUF3899 PF13038.6 OEU06914.1 - 0.0021 18.5 0.8 0.0053 17.2 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3899) YL1 PF05764.13 OEU06914.1 - 0.0041 17.3 6.1 0.0057 16.8 6.0 1.3 1 1 0 1 1 1 1 YL1 nuclear protein DUF4366 PF14283.6 OEU06914.1 - 0.012 15.7 2.9 0.012 15.7 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF5383 PF17355.2 OEU06914.1 - 0.15 12.4 2.8 0.45 10.9 0.3 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5383) DUF2370 PF10176.9 OEU06914.1 - 1.9 8.1 6.4 0.63 9.7 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) Kinesin PF00225.23 OEU06917.1 - 2.2e-102 342.4 2.3 2.5e-102 342.2 2.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU06917.1 - 6.7e-27 94.3 0.8 1.3e-26 93.3 0.2 1.8 2 0 0 2 2 2 1 Microtubule binding AAA_7 PF12775.7 OEU06917.1 - 0.076 12.5 0.1 0.21 11.1 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OEU06917.1 - 0.15 12.5 0.1 0.35 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OEU06917.1 - 0.34 11.2 0.1 0.34 11.2 0.1 2.2 3 1 0 3 3 3 0 AAA domain SUZ PF12752.7 OEU06917.1 - 0.42 11.4 2.7 0.81 10.5 0.1 2.6 3 0 0 3 3 3 0 SUZ domain zf-MYND PF01753.18 OEU06918.1 - 0.00012 22.0 19.7 0.00012 22.0 19.7 2.0 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 OEU06918.1 - 0.084 13.2 18.1 0.2 12.0 18.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CbiC PF02570.15 OEU06918.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase AAA PF00004.29 OEU06919.1 - 3e-30 105.4 0.0 1.2e-29 103.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU06919.1 - 2.9e-05 24.1 0.2 0.0019 18.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU06919.1 - 3.9e-05 24.0 0.0 7.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OEU06919.1 - 0.00022 20.7 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 OEU06919.1 - 0.00022 21.4 0.0 0.00029 21.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 OEU06919.1 - 0.00023 20.9 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU06919.1 - 0.0065 16.9 0.6 0.019 15.3 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 OEU06919.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 KaiC RNA_helicase PF00910.22 OEU06919.1 - 0.0087 16.4 0.3 0.028 14.8 0.2 2.1 2 1 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 OEU06919.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OEU06919.1 - 0.013 15.0 0.2 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OEU06919.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OEU06919.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 OEU06919.1 - 0.026 15.0 0.0 0.032 14.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 OEU06919.1 - 0.042 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 OEU06919.1 - 0.079 12.7 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 OEU06919.1 - 0.13 11.8 0.0 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 OEU06919.1 - 0.13 11.7 0.0 8.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 OEU06919.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OEU06919.1 - 0.19 12.0 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sec1 PF00995.23 OEU06920.1 - 8.6e-75 253.1 0.0 9.6e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PNRC PF15365.6 OEU06921.1 - 6.9e-05 22.5 0.9 6.9e-05 22.5 0.9 3.1 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif Bromodomain PF00439.25 OEU06922.1 - 8.5e-12 45.0 0.0 2e-10 40.6 0.0 2.6 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 OEU06922.1 - 2.3e-06 27.4 9.5 8.6e-06 25.6 9.5 2.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OEU06922.1 - 0.00066 19.2 1.1 0.00066 19.2 1.1 1.9 2 0 0 2 2 2 1 PHD-finger HemY_N PF07219.13 OEU06923.1 - 0.053 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TPR_10 PF13374.6 OEU06923.1 - 0.081 12.8 0.9 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU06923.1 - 0.11 12.7 0.2 20 5.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU06923.1 - 0.16 12.2 0.4 22 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 OEU06924.1 - 2.3e-10 40.9 0.7 2.6e-10 40.8 0.7 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Cwf_Cwc_15 PF04889.12 OEU06925.1 - 0.27 10.9 5.4 0.35 10.6 5.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 OEU06925.1 - 0.68 8.0 5.5 0.71 7.9 5.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4258 PF14076.6 OEU06926.1 - 5.8e-07 29.8 0.1 1.1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) VWA_2 PF13519.6 OEU06926.1 - 0.00025 21.6 0.0 0.0007 20.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OEU06926.1 - 0.041 13.3 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Alpha_kinase PF02816.18 OEU06927.1 - 3.3e-12 46.9 1.1 8.8e-09 35.7 0.1 2.2 2 0 0 2 2 2 2 Alpha-kinase family PrmA PF06325.13 OEU06928.1 - 3.5e-09 36.5 0.1 6e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OEU06928.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU06928.1 - 2.1e-05 25.2 0.1 6.7e-05 23.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU06928.1 - 2.4e-05 24.1 0.0 7.2e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU06928.1 - 0.00011 22.8 0.1 0.00036 21.1 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 OEU06928.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 OEU06928.1 - 0.0025 18.8 0.0 0.0067 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OEU06928.1 - 0.0044 17.0 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OEU06928.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 OEU06928.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OEU06928.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase_6 PF13344.6 OEU06930.1 - 1.5e-12 47.5 0.0 4.7e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU06930.1 - 7.9e-07 29.1 0.0 2.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OEU06930.1 - 0.053 13.8 0.1 0.41 10.9 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MGS PF02142.22 OEU06931.1 - 0.0016 18.6 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Neur_chan_LBD PF02931.23 OEU06932.1 - 3.1e-17 62.7 0.0 5.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OEU06932.1 - 9.1e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L26 PF16906.5 OEU06933.1 - 3.9e-32 110.6 3.1 5e-32 110.2 3.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OEU06933.1 - 7.3e-06 25.7 0.9 1.4e-05 24.9 0.9 1.5 1 0 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.14 OEU06933.1 - 0.062 12.6 0.2 0.09 12.1 0.1 1.4 1 1 0 1 1 1 0 RNA methyltransferase DUF2120 PF09893.9 OEU06933.1 - 0.068 13.3 0.1 0.12 12.5 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Ribosomal_S3_C PF00189.20 OEU06934.1 - 4.1e-19 68.9 2.3 1.8e-18 66.8 2.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OEU06934.1 - 3.8e-11 42.6 0.1 7.1e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 KH domain Baculo_LEF-10 PF07206.11 OEU06934.1 - 2 8.7 3.4 40 4.5 0.0 2.4 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) RRM_1 PF00076.22 OEU06935.1 - 4.9e-19 67.9 0.0 5.3e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU06935.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5027 PF16430.5 OEU06935.1 - 0.093 12.5 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) 2OG-FeII_Oxy_3 PF13640.6 OEU06936.1 - 6.3e-16 59.1 0.0 9.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU06936.1 - 5e-08 33.5 0.0 8.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OEU06936.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CIA30 PF08547.12 OEU06937.1 - 1.4e-21 77.2 0.0 1.6e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) LRR_9 PF14580.6 OEU06938.1 - 0.0087 15.6 3.8 0.28 10.7 0.1 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OEU06938.1 - 6.4 6.6 11.3 2.6 7.9 0.7 3.9 3 1 0 3 3 3 0 Leucine rich repeat DUF2628 PF10947.8 OEU06940.1 - 3.7 8.0 7.7 2.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Claudin_2 PF13903.6 OEU06941.1 - 0.0068 16.2 5.2 0.012 15.4 5.2 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SPP PF06550.11 OEU06941.1 - 0.29 10.6 4.5 0.42 10.0 4.5 1.2 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease Ammonium_transp PF00909.21 OEU06941.1 - 0.36 9.5 10.6 0.029 13.1 5.5 1.6 1 1 1 2 2 2 0 Ammonium Transporter Family PP2C PF00481.21 OEU06942.1 - 3.4e-57 194.0 0.0 4.4e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Asp_protease_2 PF13650.6 OEU06943.1 - 0.0054 17.3 0.1 0.024 15.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Arg_decarbox_C PF17944.1 OEU06943.1 - 0.21 12.2 0.7 5.8 7.6 0.1 3.7 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension DZR PF12773.7 OEU06943.1 - 7.9 6.6 8.1 0.96 9.5 1.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon Asp_protease_2 PF13650.6 OEU06944.1 - 0.016 15.8 1.5 0.38 11.4 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease DUF3568 PF12092.8 OEU06944.1 - 0.064 13.3 0.3 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) gag-asp_proteas PF13975.6 OEU06944.1 - 0.099 13.2 0.0 0.8 10.3 0.0 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1980 PF09323.10 OEU06945.1 - 0.044 13.7 0.4 0.044 13.7 0.4 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1980) DUF641 PF04859.12 OEU06946.1 - 0.3 11.4 3.2 0.55 10.6 3.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HSP70 PF00012.20 OEU06949.1 - 4.1e-173 576.8 20.4 6.5e-164 546.4 8.5 3.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OEU06949.1 - 3.1e-20 72.3 1.5 1.1e-16 60.6 0.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 OEU06949.1 - 0.00044 20.0 0.0 0.0034 17.1 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Ppx-GppA PF02541.16 OEU06949.1 - 0.0011 18.5 0.5 0.0011 18.5 0.5 1.7 2 0 0 2 2 2 1 Ppx/GppA phosphatase family BcrAD_BadFG PF01869.20 OEU06949.1 - 0.0021 17.6 0.0 0.16 11.5 0.0 2.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PilM_2 PF11104.8 OEU06949.1 - 0.0025 16.9 0.1 0.23 10.4 0.0 2.3 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; FtsA PF14450.6 OEU06949.1 - 0.0035 17.8 2.1 0.77 10.2 0.1 3.2 4 0 0 4 4 4 1 Cell division protein FtsA baeRF_family10 PF18854.1 OEU06949.1 - 0.063 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Raco_middle PF17651.1 OEU06949.1 - 0.078 12.7 0.5 2.7 7.7 0.0 3.4 3 1 0 4 4 4 0 RACo middle region DDE_Tnp_IS1 PF03400.13 OEU06949.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase Ank_2 PF12796.7 OEU06951.1 - 7.2e-14 52.1 0.0 8.8e-12 45.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU06951.1 - 1.8e-10 40.9 0.0 0.00067 19.9 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU06951.1 - 7.6e-10 38.2 0.0 0.00013 22.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OEU06951.1 - 3.9e-09 36.9 0.1 4.2e-05 24.0 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU06951.1 - 3.1e-07 30.6 0.0 0.49 10.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat DUF5424 PF17462.2 OEU06951.1 - 0.0015 18.5 0.0 0.0049 16.8 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5424) Lin0512_fam PF09585.10 OEU06951.1 - 0.093 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) TPR_7 PF13176.6 OEU06953.1 - 0.003 17.5 2.6 3.5 7.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU06953.1 - 0.45 10.9 6.2 0.77 10.1 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU06953.1 - 0.57 10.5 9.3 5.1 7.5 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU06953.1 - 0.58 10.4 5.9 1 9.6 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat AAA_18 PF13238.6 OEU06955.1 - 0.037 14.6 0.3 0.27 11.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF2482 PF10655.9 OEU06957.1 - 0.049 14.1 0.1 0.12 12.9 0.1 1.7 1 1 1 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Glyco_transf_41 PF13844.6 OEU06958.1 - 3.7e-14 52.0 0.0 2.7e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 41 Totivirus_coat PF05518.11 OEU06959.1 - 0.12 10.4 0.5 0.15 10.1 0.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein UspA1_rep PF18792.1 OEU06960.1 - 2.9e-25 86.5 138.7 0.0037 17.6 2.1 16.3 17 0 0 17 17 17 13 Ubiquitous surface protein adhesin repeat DUF4361 PF14274.6 OEU06960.1 - 0.042 14.1 2.3 0.075 13.3 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) GP41 PF00517.17 OEU06960.1 - 0.22 11.4 4.3 0.31 10.9 4.3 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Med9 PF07544.13 OEU06960.1 - 1.4 9.0 9.4 2.5 8.2 9.4 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_Xtn PF12848.7 OEU06960.1 - 1.5 8.9 10.2 0.3 11.1 6.1 1.9 1 1 1 2 2 2 0 ABC transporter Nefa_Nip30_N PF10187.9 OEU06960.1 - 2.1 8.7 9.9 1.4 9.4 7.8 1.6 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DivIC PF04977.15 OEU06960.1 - 2.5 7.9 9.9 1.8 8.4 8.1 1.7 1 1 0 1 1 1 0 Septum formation initiator OST3_OST6 PF04756.13 OEU06962.1 - 0.19 11.0 0.4 1.3 8.3 0.1 2.3 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family DUF962 PF06127.11 OEU06963.1 - 4.7e-15 55.4 3.7 8.1e-15 54.7 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF962) R3H-assoc PF13902.6 OEU06964.1 - 0.037 14.4 0.6 0.067 13.6 0.6 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain HSF_DNA-bind PF00447.17 OEU06965.1 - 4.7e-19 68.8 0.0 4.7e-19 68.8 0.0 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding ABC_tran PF00005.27 OEU06966.1 - 3.1e-13 50.4 0.0 5.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU06966.1 - 2.3e-09 37.5 0.0 0.00059 19.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU06966.1 - 2e-05 24.1 0.3 0.15 11.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OEU06966.1 - 0.00017 21.2 0.1 0.00039 20.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU06966.1 - 0.0026 18.3 0.1 0.0045 17.5 0.1 1.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OEU06966.1 - 0.0051 16.9 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OEU06966.1 - 0.0067 16.8 0.0 0.0088 16.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OEU06966.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 OEU06966.1 - 0.012 15.6 0.2 0.044 13.7 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 OEU06966.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OEU06966.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 OEU06966.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OEU06966.1 - 0.026 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 OEU06966.1 - 0.026 13.9 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 OEU06966.1 - 0.029 14.8 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU06966.1 - 0.031 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU06966.1 - 0.034 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU06966.1 - 0.035 14.2 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OEU06966.1 - 0.043 14.1 0.4 0.1 12.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 OEU06966.1 - 0.054 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Zeta_toxin PF06414.12 OEU06966.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_8 PF12780.7 OEU06966.1 - 0.067 12.5 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 OEU06966.1 - 0.071 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 OEU06966.1 - 0.082 13.1 0.5 0.16 12.2 0.2 1.9 2 1 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 OEU06966.1 - 0.084 12.9 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OEU06966.1 - 0.1 13.0 0.1 0.25 11.8 0.0 1.7 2 0 0 2 2 1 0 RNA helicase MFS_1 PF07690.16 OEU06967.1 - 1.3e-24 86.8 32.3 1.3e-24 86.8 32.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-MYND PF01753.18 OEU06968.1 - 2.3e-07 30.8 15.1 5.1e-07 29.7 15.1 1.6 1 0 0 1 1 1 1 MYND finger Guanylate_cyc PF00211.20 OEU06969.1 - 2.4e-08 33.8 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain IL6 PF00489.17 OEU06970.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family UPF0121 PF03661.13 OEU06970.1 - 0.1 12.0 0.1 0.1 12.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Sulfotransfer_1 PF00685.27 OEU06971.1 - 1.6e-06 27.8 2.3 3.3e-05 23.5 2.3 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Paramyxo_ncap PF00973.19 OEU06971.1 - 0.81 8.5 8.5 1.6 7.5 8.5 1.5 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ysc84 PF04366.12 OEU06972.1 - 4.7e-29 100.7 0.1 1.2e-28 99.4 0.1 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF4113 PF13438.6 OEU06972.1 - 0.097 12.8 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) ThrE PF06738.12 OEU06973.1 - 7.1e-09 35.4 1.5 7.1e-09 35.4 1.5 2.3 2 0 0 2 2 2 1 Putative threonine/serine exporter DUF1179 PF06678.11 OEU06973.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) SIT PF15330.6 OEU06973.1 - 0.15 12.5 0.1 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT YibE_F PF07907.11 OEU06973.1 - 0.78 9.2 13.0 0.046 13.2 2.5 2.9 3 0 0 3 3 3 0 YibE/F-like protein LRR_4 PF12799.7 OEU06974.1 - 4.7e-21 74.5 20.6 3.9e-06 27.1 2.2 4.2 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU06974.1 - 5.8e-14 51.6 19.9 3.4e-06 26.7 3.4 3.2 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 OEU06974.1 - 4.1e-07 29.6 14.7 9.5 7.2 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat ATP-synt_ab PF00006.25 OEU06974.1 - 0.0048 16.6 0.0 2.8 7.5 0.0 2.8 1 1 2 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3338 PF11819.8 OEU06974.1 - 0.013 15.4 0.1 3.1 7.8 0.0 3.4 3 2 0 4 4 4 0 Domain of unknown function (DUF3338) JmjC PF02373.22 OEU06974.1 - 0.19 12.2 0.1 31 5.1 0.0 2.5 2 1 0 2 2 2 0 JmjC domain, hydroxylase LRR_2 PF07723.13 OEU06974.1 - 0.3 11.8 9.1 1.2e+02 3.6 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich Repeat Phage_holin_2_1 PF04971.12 OEU06974.1 - 0.33 11.0 4.9 0.86 9.7 0.0 3.5 4 0 0 4 4 4 0 Bacteriophage P21 holin S LRR_6 PF13516.6 OEU06974.1 - 0.37 10.9 27.4 20 5.5 0.2 6.5 7 0 0 7 7 7 0 Leucine Rich repeat Leader_Trp PF08255.11 OEU06974.1 - 0.85 9.7 7.1 74 3.7 0.2 4.1 3 0 0 3 3 3 0 Trp-operon Leader Peptide SPP PF06550.11 OEU06976.1 - 0.059 12.8 6.8 0.11 12.0 6.8 1.4 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease DUF3413 PF11893.8 OEU06976.1 - 1.7 7.7 11.3 1.5 8.0 8.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) NFACT-R_1 PF05670.13 OEU06978.1 - 1.8e-35 121.9 0.4 3.2e-35 121.1 0.4 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain ICA69 PF04629.14 OEU06978.1 - 0.44 10.8 10.3 0.47 10.7 9.2 1.4 1 1 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain TBK1_ULD PF18396.1 OEU06978.1 - 0.85 9.6 5.6 8.1 6.5 1.5 3.1 2 1 1 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain DUF4140 PF13600.6 OEU06978.1 - 1.6 9.2 5.7 3.8 8.0 5.7 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.16 OEU06978.1 - 1.9 7.3 4.7 2.1 7.2 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S49_N PF08496.10 OEU06978.1 - 8.2 6.5 11.7 18 5.4 11.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal 2OG-FeII_Oxy_3 PF13640.6 OEU06979.1 - 2.7e-09 37.8 1.3 4.2e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OEU06979.1 - 0.00077 19.8 0.2 0.17 12.3 0.0 3.0 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_4 PF13661.6 OEU06979.1 - 0.0033 18.0 0.3 0.16 12.6 0.0 2.8 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily EDR1 PF14381.6 OEU06979.1 - 0.068 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Pinin_SDK_N PF04697.13 OEU06979.1 - 0.51 11.0 3.2 2 9.0 3.2 2.1 1 0 0 1 1 1 0 pinin/SDK conserved region DUF572 PF04502.13 OEU06979.1 - 5.2 6.6 14.9 1.4 8.5 1.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4551 PF15087.6 OEU06980.1 - 0.86 8.4 11.2 1.1 8.0 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4114 PF13448.6 OEU06980.1 - 2.3 9.0 4.0 11 6.9 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4114) WD40 PF00400.32 OEU06981.1 - 1.1e-28 98.9 30.5 5.5e-06 27.0 0.3 10.6 10 1 0 10 10 10 7 WD domain, G-beta repeat Utp12 PF04003.12 OEU06981.1 - 3.3e-22 78.8 0.2 7.1e-22 77.7 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OEU06981.1 - 8.7e-21 74.0 0.1 0.053 13.8 0.0 8.4 4 3 4 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU06981.1 - 2e-06 27.0 0.1 1.8 7.4 0.0 4.9 3 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Utp13 PF08625.11 OEU06981.1 - 0.043 13.7 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain zf-RING_2 PF13639.6 OEU06982.1 - 1.1e-05 25.7 1.5 1.1e-05 25.7 1.5 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OEU06982.1 - 0.0016 18.1 4.0 0.0045 16.7 4.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 OEU06982.1 - 0.0018 18.4 1.3 0.0018 18.4 1.3 2.5 3 0 0 3 3 3 1 FANCL C-terminal domain SRTM1 PF15872.5 OEU06982.1 - 0.024 14.8 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 zf-C3HC4 PF00097.25 OEU06982.1 - 0.049 13.5 0.8 0.049 13.5 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU06982.1 - 0.05 13.6 0.4 0.05 13.6 0.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU06982.1 - 0.12 12.3 6.2 0.081 12.8 1.0 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 OEU06982.1 - 0.49 10.9 9.8 1.5 9.3 2.0 3.0 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 TIG PF01833.24 OEU06984.1 - 2e-06 27.8 0.0 2e-06 27.8 0.0 2.7 3 0 0 3 3 3 1 IPT/TIG domain AAA PF00004.29 OEU06984.1 - 3.9e-05 24.1 3.9 0.00053 20.4 1.2 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Med26 PF08711.11 OEU06984.1 - 9.6e-05 22.3 0.1 0.00023 21.1 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Rad17 PF03215.15 OEU06984.1 - 0.0003 20.8 1.3 0.031 14.2 0.2 2.6 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 OEU06984.1 - 0.0009 19.7 0.0 0.0035 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OEU06984.1 - 0.0081 16.7 0.3 0.043 14.4 0.3 2.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OEU06984.1 - 0.032 14.3 0.2 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OEU06984.1 - 0.043 14.1 1.4 0.081 13.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OEU06984.1 - 0.064 13.2 1.4 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OEU06984.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.5 3 0 0 3 3 3 0 AAA domain Complex1_51K PF01512.17 OEU06985.1 - 2.9e-49 166.8 0.0 5.2e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OEU06985.1 - 1.2e-29 102.2 0.1 2.4e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OEU06985.1 - 1.3e-09 37.7 0.0 4e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 SLBB domain ICEA PF05315.11 OEU06985.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 ICEA Protein DUF2207 PF09972.9 OEU06987.1 - 0.016 14.0 0.3 0.016 14.0 0.3 2.9 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) FKBP_C PF00254.28 OEU06988.1 - 2.7e-10 40.4 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase mTERF PF02536.14 OEU06989.1 - 9.8e-30 103.6 0.0 8.1e-16 57.8 0.0 3.5 2 2 1 3 3 3 3 mTERF DUF3246 PF11596.8 OEU06990.1 - 0.024 14.1 0.1 0.039 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MGDG_synth PF06925.11 OEU06991.1 - 1.4e-21 77.4 0.0 1.9e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 OEU06991.1 - 1.1e-11 45.1 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 OEU06991.1 - 0.00027 21.4 0.1 0.00052 20.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OEU06991.1 - 0.024 14.2 0.0 0.078 12.5 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 Exostosin PF03016.15 OEU06992.1 - 5.2e-15 55.4 6.2 1.6e-13 50.6 6.2 2.4 1 1 0 1 1 1 1 Exostosin family RRM_1 PF00076.22 OEU06993.1 - 5.5e-19 67.8 0.0 6.4e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OEU06993.1 - 0.00017 21.5 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 DbpA RNA binding domain Herpes_UL69 PF05459.12 OEU06993.1 - 0.23 10.8 0.0 0.25 10.7 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family VWA_3 PF13768.6 OEU06994.1 - 1.9e-16 60.4 0.0 1.2e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OEU06994.1 - 1.8e-12 47.9 0.0 3.2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OEU06994.1 - 1.6e-07 31.9 0.0 3.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OEU06994.1 - 0.02 14.3 0.0 0.22 10.9 0.0 2.2 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.8 OEU06994.1 - 0.023 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain vWA-TerF-like PF10138.9 OEU06994.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus S-AdoMet_synt_N PF00438.20 OEU06995.1 - 0.023 15.4 39.2 2.2 9.0 1.0 7.3 1 1 4 5 5 5 0 S-adenosylmethionine synthetase, N-terminal domain Yae1_N PF09811.9 OEU06995.1 - 0.091 12.5 6.3 1.1 9.1 0.0 5.3 7 1 0 7 7 7 0 Essential protein Yae1, N terminal CCDC117 PF15810.5 OEU06995.1 - 3.9 7.8 4.8 1e+02 3.1 0.1 3.7 1 1 5 6 6 6 0 Coiled-coil domain-containing protein 117 FtsJ PF01728.19 OEU06996.1 - 2.7e-07 30.9 0.0 7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase RRM_1 PF00076.22 OEU06996.1 - 1.8e-06 27.7 1.3 0.0011 18.7 0.3 3.6 2 2 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YtzH PF14165.6 OEU06999.1 - 0.56 10.6 14.2 0.12 12.8 0.5 3.2 2 1 1 3 3 3 0 YtzH-like protein DUF5542 PF17696.1 OEU06999.1 - 0.66 10.1 1.9 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5542) NCKAP5 PF15246.6 OEU06999.1 - 5.3 6.6 18.7 5.3 6.6 8.9 2.5 2 1 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Peripla_BP_4 PF13407.6 OEU07000.1 - 5.7e-13 49.0 0.0 9.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF4758 PF15950.5 OEU07000.1 - 1.9 8.9 6.9 0.41 11.0 2.0 2.3 2 1 0 2 2 2 0 Putative sperm flagellar membrane protein TMEM51 PF15345.6 OEU07001.1 - 0.074 12.9 0.0 0.074 12.9 0.0 3.5 4 0 0 4 4 4 0 Transmembrane protein 51 FAM176 PF14851.6 OEU07001.1 - 0.084 12.5 0.0 0.084 12.5 0.0 4.6 4 2 1 5 5 5 0 FAM176 family DUF4010 PF13194.6 OEU07001.1 - 9.6 5.8 9.3 6.1 6.5 7.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) PDDEXK_1 PF12705.7 OEU07003.1 - 1.2e-07 31.9 0.3 3.7e-05 23.8 0.1 2.1 1 1 1 2 2 2 2 PD-(D/E)XK nuclease superfamily PhyH PF05721.13 OEU07004.1 - 2.3e-12 47.6 0.0 9.7e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Prokineticin PF06607.11 OEU07007.1 - 0.16 12.3 2.4 0.18 12.1 1.1 1.7 1 1 1 2 2 2 0 Prokineticin Mago_nashi PF02792.14 OEU07007.1 - 0.16 12.1 1.7 0.29 11.2 1.7 1.4 1 0 0 1 1 1 0 Mago nashi protein DUF1351 PF07083.11 OEU07010.1 - 0.0077 16.0 2.1 0.0077 16.0 2.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1351) DUF2681 PF10883.8 OEU07010.1 - 0.56 10.6 6.3 1.6 9.2 6.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) MscS_TM PF12794.7 OEU07010.1 - 0.66 8.8 2.0 1 8.1 2.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FliD_N PF02465.18 OEU07011.1 - 4.1 8.2 15.6 1.4 9.7 4.8 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ferric_reduct PF01794.19 OEU07012.1 - 1.6e-06 28.3 9.5 4.4e-06 26.8 9.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OEU07012.1 - 3.6e-05 23.9 0.0 0.00027 21.1 0.0 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 OEU07012.1 - 0.025 15.2 0.0 0.14 12.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4176 PF13780.6 OEU07013.1 - 0.17 12.0 0.0 0.83 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) PMSR PF01625.21 OEU07016.1 - 9.4e-39 133.0 6.6 1.6e-20 73.8 0.6 2.4 1 1 1 2 2 2 2 Peptide methionine sulfoxide reductase Vsr PF03852.15 OEU07016.1 - 0.097 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr His_Phos_1 PF00300.22 OEU07017.1 - 7.2e-62 208.5 0.0 3.5e-26 92.1 0.0 4.2 3 1 0 4 4 4 4 Histidine phosphatase superfamily (branch 1) MqsR_toxin PF15723.5 OEU07018.1 - 0.062 13.7 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Tox-REase-3 PF15647.6 OEU07019.1 - 0.14 12.4 5.0 12 6.2 0.2 4.1 1 1 6 7 7 7 0 Restriction endonuclease fold toxin 3 DUF3659 PF12396.8 OEU07019.1 - 4.1 7.4 11.0 9.9 6.2 0.1 4.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3659) RNA_polI_A34 PF08208.11 OEU07020.1 - 0.025 14.7 9.8 0.032 14.3 9.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PPL5 PF18168.1 OEU07020.1 - 0.026 13.8 3.3 0.036 13.3 3.3 1.3 1 0 0 1 1 1 0 Prim-pol family 5 TerB_C PF15615.6 OEU07020.1 - 0.029 14.7 4.4 0.047 14.0 4.4 1.3 1 0 0 1 1 1 0 TerB-C domain CMS1 PF14617.6 OEU07020.1 - 0.034 13.5 8.5 0.057 12.7 8.5 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF637 PF04830.13 OEU07020.1 - 0.039 13.8 0.3 0.054 13.3 0.3 1.3 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) AIF_C PF14721.6 OEU07020.1 - 0.056 13.8 4.6 0.092 13.1 4.5 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term bMG10 PF17973.1 OEU07020.1 - 0.069 13.4 0.4 0.088 13.0 0.4 1.2 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain KRAB PF01352.27 OEU07020.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 KRAB box EIIBC-GUT_N PF03612.14 OEU07020.1 - 0.14 11.8 4.7 0.21 11.3 4.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Vfa1 PF08432.10 OEU07020.1 - 0.41 11.0 11.7 0.55 10.5 11.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.19 OEU07020.1 - 1.9 8.2 5.0 2.4 7.9 5.0 1.3 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 OEU07020.1 - 3.1 7.6 6.1 4.8 6.9 6.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Sec62 PF03839.16 OEU07020.1 - 8.3 5.9 12.0 11 5.4 12.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3494 PF11999.8 OEU07021.1 - 8.8e-33 113.7 8.0 9.9e-33 113.5 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DDE_Tnp_1_7 PF13843.6 OEU07024.1 - 9.1e-10 38.4 0.1 1.2e-07 31.4 0.1 2.3 2 0 0 2 2 2 2 Transposase IS4 zf-CCCH PF00642.24 OEU07025.1 - 2.7e-11 43.1 27.3 3e-08 33.4 4.0 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OEU07025.1 - 5.8e-09 35.5 21.0 2.2e-07 30.5 5.1 2.7 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OEU07025.1 - 1.2e-06 28.3 33.8 1.9e-05 24.6 7.1 3.5 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 OEU07025.1 - 3.8e-06 27.5 13.9 0.0007 20.3 0.4 3.1 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 OEU07025.1 - 0.0064 16.9 17.0 0.017 15.6 4.6 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger DUF2931 PF11153.8 OEU07025.1 - 0.038 13.7 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) zf-CCCH_3 PF15663.5 OEU07025.1 - 0.09 13.0 6.9 0.39 11.0 6.9 1.9 1 1 0 1 1 1 0 Zinc-finger containing family Spt5_N PF11942.8 OEU07025.1 - 0.63 11.1 12.8 0.61 11.1 4.5 3.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4789 PF16033.5 OEU07025.1 - 3.2 8.3 9.7 19 5.9 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4789) DUF3439 PF11921.8 OEU07026.1 - 0.11 12.5 5.4 0.14 12.2 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 OEU07026.1 - 0.26 11.2 14.5 0.32 11.0 14.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 OEU07026.1 - 0.71 7.8 1.2 0.66 7.9 1.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 OEU07026.1 - 5.5 5.0 8.1 6 4.9 8.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4834 PF16118.5 OEU07027.1 - 0.0038 18.1 0.9 0.052 14.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) BTB PF00651.31 OEU07028.1 - 5.4e-10 39.5 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain LapD_MoxY_N PF16448.5 OEU07029.1 - 0.39 10.6 2.8 9.5 6.1 0.1 2.3 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain ShK PF01549.24 OEU07030.1 - 1.7e-14 54.0 28.6 3e-07 30.8 6.4 3.3 2 1 1 3 3 3 3 ShK domain-like TFIIA PF03153.13 OEU07031.1 - 0.038 14.0 51.4 0.1 12.6 15.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RteC PF09357.10 OEU07032.1 - 0.018 14.7 0.1 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 RteC protein Apis_Csd PF11671.8 OEU07032.1 - 0.025 14.6 0.9 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein GreA_GreB PF01272.19 OEU07034.1 - 0.045 13.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term DUF3450 PF11932.8 OEU07034.1 - 0.15 11.3 4.7 0.28 10.4 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 OEU07034.1 - 0.59 10.8 2.1 3.7 8.2 2.1 2.4 2 0 0 2 2 2 0 SlyX A_deaminase PF00962.22 OEU07035.1 - 2.1e-16 60.1 0.0 3.6e-16 59.4 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase Trypsin_2 PF13365.6 OEU07036.1 - 6.6e-18 66.0 0.0 8.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pilin_N PF07790.11 OEU07039.1 - 0.14 13.0 0.3 0.43 11.5 0.1 1.9 1 1 1 2 2 2 0 Archaeal Type IV pilin, N-terminal MMR_HSR1_Xtn PF16897.5 OEU07040.1 - 1.7e-36 124.4 0.1 2.9e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OEU07040.1 - 2.6e-19 69.4 0.0 5.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OEU07040.1 - 8.4e-17 61.0 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OEU07040.1 - 4.2e-10 39.4 0.0 8.5e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU07040.1 - 0.00058 20.0 0.0 0.72 9.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 OEU07040.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 OEU07040.1 - 0.027 13.4 0.1 0.046 12.7 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 OEU07040.1 - 0.15 12.6 0.1 0.47 11.0 0.1 1.8 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 OEU07040.1 - 0.17 12.1 0.0 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MOSC PF03473.17 OEU07042.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain CENP-B_dimeris PF09026.10 OEU07042.1 - 0.013 15.9 4.6 0.013 15.9 4.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pro_isomerase PF00160.21 OEU07043.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phytochelatin PF05023.14 OEU07045.1 - 4.4e-08 32.6 1.1 3e-05 23.3 0.9 3.2 1 1 0 1 1 1 1 Phytochelatin synthase SR-25 PF10500.9 OEU07047.1 - 1.4 8.5 17.5 0.042 13.4 7.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.19 OEU07048.1 - 1.1e-21 77.5 0.0 1.7e-14 53.9 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 OEU07048.1 - 1.1e-07 31.2 0.1 1.5e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 OEU07048.1 - 0.092 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Secretin_N_2 PF07655.13 OEU07050.1 - 0.024 15.1 2.7 0.024 15.1 2.7 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain YlqD PF11068.8 OEU07050.1 - 0.2 12.0 2.5 0.43 10.9 1.9 1.8 2 0 0 2 2 2 0 YlqD protein Kelch_3 PF13415.6 OEU07052.1 - 1.6e-27 95.2 8.7 3.9e-08 33.4 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OEU07052.1 - 2.9e-19 68.6 7.5 2.1e-06 27.8 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OEU07052.1 - 4.2e-19 68.1 1.6 0.00022 21.1 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 OEU07052.1 - 2.2e-18 66.0 13.9 1.2e-05 25.2 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OEU07052.1 - 1e-12 47.5 5.2 0.0011 18.9 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OEU07052.1 - 9.3e-10 37.9 1.9 5.2e-05 22.8 0.1 4.6 5 0 0 5 5 5 2 Kelch motif RAG2 PF03089.14 OEU07052.1 - 0.046 12.7 0.0 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Recombination activating protein 2 Cyclin PF08613.11 OEU07053.1 - 0.045 14.1 0.5 0.073 13.4 0.5 1.3 1 0 0 1 1 1 0 Cyclin LMBR1 PF04791.16 OEU07053.1 - 0.54 9.1 1.8 0.68 8.8 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SSP160 PF06933.11 OEU07053.1 - 6.8 4.7 14.5 0.66 8.1 9.6 1.6 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Glycos_transf_1 PF00534.20 OEU07054.1 - 0.0034 16.9 0.1 0.1 12.1 0.0 2.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OEU07054.1 - 0.082 13.3 0.1 0.57 10.6 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 Aminotran_3 PF00202.21 OEU07055.1 - 7.6e-114 380.5 0.1 9.8e-114 380.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III RNase_T PF00929.24 OEU07057.1 - 2.2e-08 34.8 0.4 3.3e-07 31.0 0.4 2.5 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 OEU07057.1 - 0.023 14.7 0.2 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like Macoilin PF09726.9 OEU07058.1 - 1.7 7.1 34.7 2.3 6.7 34.7 1.3 1 0 0 1 1 1 0 Macoilin family Activator_LAG-3 PF11498.8 OEU07058.1 - 1.9 7.3 48.5 0.69 8.8 3.9 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 OmpH PF03938.14 OEU07058.1 - 5.9 7.2 43.5 0.68 10.3 4.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Paf1 PF03985.13 OEU07059.1 - 0.023 13.7 24.4 0.034 13.1 24.4 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 OEU07059.1 - 0.93 8.8 24.4 1.9 7.8 24.4 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OEU07059.1 - 2.8 6.1 18.5 4.6 5.4 18.5 1.5 1 0 0 1 1 1 0 CDC45-like protein Serinc PF03348.15 OEU07059.1 - 5.3 5.8 4.8 8.3 5.2 4.8 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ion_trans_2 PF07885.16 OEU07060.1 - 1.5e-31 108.2 22.1 2.6e-17 62.5 13.8 2.3 2 0 0 2 2 2 2 Ion channel EF-hand_5 PF13202.6 OEU07060.1 - 1.3e-07 30.8 1.3 0.0033 16.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OEU07060.1 - 5.9e-07 28.6 3.7 0.0061 16.0 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OEU07060.1 - 6.8e-07 29.6 1.3 0.024 15.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU07060.1 - 6.9e-07 28.7 2.4 0.016 15.1 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU07060.1 - 1.8e-05 24.5 2.6 0.01 15.7 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair Ion_trans PF00520.31 OEU07060.1 - 0.00062 19.1 14.7 0.011 15.0 9.8 2.5 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 OEU07060.1 - 0.0092 15.8 0.1 1.2 9.0 0.0 2.6 2 1 1 3 3 3 1 Ligand-gated ion channel UDPGP PF01704.18 OEU07061.1 - 6.9e-121 403.8 0.0 8.6e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 OEU07061.1 - 2.5e-24 85.6 0.0 4.2e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I LemA PF04011.12 OEU07061.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 LemA family DUF4834 PF16118.5 OEU07062.1 - 0.0011 19.9 2.8 0.0036 18.2 1.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) RtcR PF06956.11 OEU07062.1 - 0.12 11.8 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase HCO3_cotransp PF00955.21 OEU07062.1 - 0.3 9.9 3.5 0.52 9.1 3.5 1.3 1 0 0 1 1 1 0 HCO3- transporter family Presenilin PF01080.17 OEU07062.1 - 0.4 9.4 2.1 0.59 8.8 2.1 1.3 1 0 0 1 1 1 0 Presenilin Arf PF00025.21 OEU07063.1 - 1.8e-09 37.3 0.0 5.6e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 OEU07063.1 - 6.3e-05 22.3 0.0 8.7e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit CDC45 PF02724.14 OEU07063.1 - 0.14 10.5 1.3 0.15 10.3 1.3 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OEU07063.1 - 4.6 6.5 8.4 5.9 6.1 8.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2164 PF09932.9 OEU07064.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Rhodanese PF00581.20 OEU07065.1 - 1e-05 26.0 0.0 4.7e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain AAA_22 PF13401.6 OEU07065.1 - 0.12 12.6 0.0 0.92 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OEU07065.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 OEU07065.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Yae1_N PF09811.9 OEU07066.1 - 7.4e-10 38.4 50.4 2.1 8.1 0.3 13.2 2 2 7 9 9 9 7 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU07066.1 - 0.0031 17.7 0.5 11 6.1 0.0 3.6 2 2 0 2 2 2 2 Outer membrane protein beta-barrel domain Rick_17kDa_Anti PF05433.15 OEU07066.1 - 0.0045 16.8 68.1 0.055 13.4 10.1 8.1 2 2 6 8 8 8 3 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OEU07066.1 - 0.058 13.4 61.8 8.9 6.4 1.2 7.3 2 2 1 3 3 3 0 Glycine zipper DUF826 PF05696.11 OEU07066.1 - 0.62 10.2 3.5 44 4.2 0.3 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF826) DUF456 PF04306.13 OEU07066.1 - 5.3 7.3 39.6 1 9.6 6.3 5.0 1 1 3 4 4 4 0 Protein of unknown function (DUF456) DUF285 PF03382.14 OEU07067.1 - 7.6e-56 187.1 24.8 4.8e-31 107.0 8.7 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 NlpE_C PF17185.4 OEU07067.1 - 0.8 10.0 3.3 1.4 9.2 0.2 2.6 3 0 0 3 3 3 0 NlpE C-terminal OB domain DDE_Tnp_1_7 PF13843.6 OEU07068.1 - 1.6e-14 54.0 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 OEU07069.1 - 1.1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 TatD_DNase PF01026.21 OEU07069.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Inhibitor_I71 PF12628.7 OEU07070.1 - 0.27 11.1 11.3 0.037 13.9 3.8 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor GREB1 PF15782.5 OEU07070.1 - 2 5.4 19.5 2.5 5.1 19.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 OEU07070.1 - 4.9 6.9 9.7 6.4 6.5 9.7 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 OEU07072.1 - 0.041 11.0 0.0 0.052 10.7 0.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ac76 PF05814.11 OEU07072.1 - 0.21 11.6 2.8 0.21 11.6 0.7 2.0 1 1 1 2 2 2 0 Orf76 (Ac76) USP8_dimer PF08969.11 OEU07073.1 - 0.011 15.9 4.3 0.014 15.5 0.1 2.9 2 1 0 2 2 2 0 USP8 dimerisation domain RVT_2 PF07727.14 OEU07074.1 - 4.4e-06 26.5 0.0 6.1e-06 26.0 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnl2_NKP2 PF09447.10 OEU07076.1 - 0.017 15.2 1.0 1.2 9.3 0.3 2.3 1 1 1 2 2 2 0 Cnl2/NKP2 family protein Mei5_like PF17021.5 OEU07076.1 - 0.029 14.4 3.1 0.057 13.5 0.2 2.2 1 1 1 2 2 2 0 Putative double-strand recombination repair-like GT-D PF08759.11 OEU07076.1 - 0.056 13.1 0.7 0.083 12.6 0.7 1.3 1 1 0 1 1 1 0 Glycosyltransferase GT-D fold DUF2207 PF09972.9 OEU07077.1 - 0.03 13.1 0.2 0.12 11.1 0.0 2.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MARVEL PF01284.23 OEU07077.1 - 0.11 12.6 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Membrane-associating domain Rod_C PF10493.9 OEU07077.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Rough deal protein C-terminal region DUF4834 PF16118.5 OEU07077.1 - 0.2 12.6 4.6 7.6 7.6 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) ETRAMP PF09716.10 OEU07077.1 - 0.29 11.2 2.8 2.7 8.1 0.2 3.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 OEU07077.1 - 0.42 10.9 1.6 23 5.4 0.0 3.7 4 0 0 4 4 4 0 Orf78 (ac78) NPF PF16601.5 OEU07078.1 - 5.4 7.4 14.7 63 4.0 14.7 2.4 1 1 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif DPM3 PF08285.11 OEU07079.1 - 0.24 11.6 3.4 1 9.6 0.7 3.0 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Sulfate_transp PF00916.20 OEU07080.1 - 5.8e-20 71.4 7.5 7.2e-20 71.1 7.5 1.1 1 0 0 1 1 1 1 Sulfate permease family PMSR PF01625.21 OEU07081.1 - 4.9e-41 140.4 0.1 6.3e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3139 PF11337.8 OEU07081.1 - 0.17 12.5 1.6 0.32 11.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SHMT PF00464.19 OEU07082.1 - 5.1e-200 664.2 0.0 6.9e-200 663.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OEU07082.1 - 0.0075 15.6 0.0 0.019 14.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OEU07082.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family rve PF00665.26 OEU07083.1 - 0.0012 19.1 0.0 0.72 10.0 0.0 2.3 2 0 0 2 2 2 2 Integrase core domain TUDOR_5 PF18359.1 OEU07084.1 - 0.0025 17.5 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 LBR_tudor PF09465.10 OEU07084.1 - 0.039 13.8 0.5 0.065 13.0 0.5 1.3 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Ccdc124 PF06244.12 OEU07084.1 - 1 9.9 6.1 2 8.9 2.5 2.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 TPR_1 PF00515.28 OEU07085.1 - 1.2e-08 34.4 4.1 0.0013 18.4 1.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU07085.1 - 1.6e-06 27.8 6.5 0.01 15.9 1.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU07085.1 - 7.1e-05 23.0 0.7 0.43 10.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU07085.1 - 0.00041 20.2 1.0 1.1 9.5 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 OEU07085.1 - 0.0039 17.2 3.4 0.043 13.9 0.3 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Macoilin PF09726.9 OEU07085.1 - 0.015 13.9 15.6 0.019 13.5 15.6 1.1 1 0 0 1 1 1 0 Macoilin family TPR_8 PF13181.6 OEU07085.1 - 0.058 13.6 1.2 14 6.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Miga PF10265.9 OEU07085.1 - 0.16 10.9 6.4 0.2 10.6 6.4 1.2 1 0 0 1 1 1 0 Mitoguardin TPR_3 PF07720.12 OEU07085.1 - 1.2 9.2 6.6 1 9.4 1.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU07085.1 - 2.5 8.8 5.4 27 5.5 1.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5383 PF17355.2 OEU07086.1 - 0.0093 16.3 0.2 0.035 14.5 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5383) DUF916 PF06030.12 OEU07086.1 - 0.077 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) T4SS-DNA_transf PF02534.14 OEU07086.1 - 0.11 11.3 2.6 0.14 10.9 2.6 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer HSF_DNA-bind PF00447.17 OEU07088.1 - 9.7e-21 74.2 3.9 1.4e-10 41.6 0.0 3.0 3 0 0 3 3 3 2 HSF-type DNA-binding Pox_G9-A16 PF03003.16 OEU07088.1 - 3.3 7.4 12.5 0.27 11.0 5.9 2.5 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 RNA_pol_L_2 PF13656.6 OEU07090.1 - 5.5e-29 99.8 0.0 7.8e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OEU07090.1 - 1.6e-11 43.5 0.0 2.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cadherin_C_2 PF16492.5 OEU07091.1 - 0.05 14.3 0.2 0.077 13.8 0.2 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal FHA PF00498.26 OEU07092.1 - 2e-10 40.8 0.0 2.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OEU07092.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 OEU07094.1 - 3.9e-10 39.4 9.2 7.8e-10 38.5 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU07094.1 - 3.6e-06 26.7 10.0 8e-06 25.6 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-MYND PF01753.18 OEU07097.1 - 4.9e-06 26.5 17.5 7.9e-06 25.9 17.5 1.3 1 0 0 1 1 1 1 MYND finger Ldh_1_C PF02866.18 OEU07098.1 - 3.8e-43 147.3 0.0 7.3e-43 146.4 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OEU07098.1 - 6.7e-41 139.7 0.0 1.4e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OEU07098.1 - 0.029 13.7 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 OEU07098.1 - 0.037 13.0 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thioredoxin PF00085.20 OEU07099.1 - 9.4e-20 70.5 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU07099.1 - 5.6e-06 26.8 0.0 2.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU07099.1 - 8e-05 22.4 0.0 9.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OEU07099.1 - 0.0011 18.7 0.1 0.0022 17.7 0.1 1.5 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 OEU07099.1 - 0.0012 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OEU07099.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 OEU07099.1 - 0.0067 16.4 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE HSF_DNA-bind PF00447.17 OEU07100.1 - 1.5e-07 31.9 0.2 1.5e-07 31.9 0.2 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Sel1 PF08238.12 OEU07101.1 - 9.5e-06 26.1 2.5 0.03 15.0 0.1 3.5 3 0 0 3 3 3 2 Sel1 repeat PDZ_6 PF17820.1 OEU07102.1 - 0.017 14.9 0.1 5.9 6.8 0.1 2.4 2 0 0 2 2 2 0 PDZ domain Utp14 PF04615.13 OEU07102.1 - 0.09 11.3 31.3 0.12 10.9 2.7 2.1 2 0 0 2 2 2 0 Utp14 protein Peptidase_C58 PF03543.14 OEU07105.1 - 0.12 12.0 1.2 0.2 11.4 1.2 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen GP24_25 PF17388.2 OEU07105.1 - 0.23 11.4 0.8 11 6.0 0.2 2.4 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 CcdA PF07362.12 OEU07105.1 - 0.29 11.6 2.6 0.68 10.4 2.6 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Gly_transf_sug PF04488.15 OEU07109.1 - 7.1e-08 33.0 0.1 1.2e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU07109.1 - 0.00085 18.7 0.1 0.0038 16.6 0.0 1.8 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Sulfotransfer_2 PF03567.14 OEU07113.1 - 7.8e-05 22.7 0.0 7.8e-05 22.7 0.0 3.3 2 1 0 3 3 3 1 Sulfotransferase family BSD PF03909.17 OEU07114.1 - 0.0015 18.5 1.0 0.0061 16.5 0.1 2.6 2 0 0 2 2 2 1 BSD domain MspA PF09203.11 OEU07116.1 - 0.24 11.3 3.6 17 5.2 1.7 3.4 1 1 1 2 2 2 0 MspA Yae1_N PF09811.9 OEU07116.1 - 0.3 10.8 29.3 21 4.9 0.0 9.3 10 2 2 12 12 12 0 Essential protein Yae1, N terminal DUF4567 PF15131.6 OEU07116.1 - 0.62 10.2 12.9 11 6.1 0.1 5.5 3 2 4 7 7 7 0 Domain of unknown function (DUF4567) DUF4980 PF16352.5 OEU07118.1 - 0.038 14.0 0.2 0.082 12.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) BUD22 PF09073.10 OEU07119.1 - 0.0011 18.5 16.0 0.0011 18.5 16.0 1.6 2 0 0 2 2 2 1 BUD22 Chorion_2 PF03964.15 OEU07119.1 - 0.38 11.6 7.8 3.8 8.4 4.7 2.6 2 0 0 2 2 2 0 Chorion family 2 CSG2 PF16965.5 OEU07119.1 - 0.46 9.4 5.9 3.1 6.6 5.3 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Ribosomal_60s PF00428.19 OEU07119.1 - 8.7 7.0 10.0 2.1 9.0 3.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Trypan_PARP PF05887.11 OEU07122.1 - 0.064 13.2 6.1 0.023 14.7 2.5 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ABM PF03992.16 OEU07123.1 - 0.00023 21.2 0.0 0.0024 18.0 0.0 2.4 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase PTS_EIIA_1 PF00358.20 OEU07124.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SDA1 PF05285.12 OEU07125.1 - 0.00045 19.8 51.7 0.0012 18.4 32.7 2.2 2 0 0 2 2 2 2 SDA1 Zip PF02535.22 OEU07125.1 - 0.23 10.6 16.4 0.13 11.4 4.4 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Opi1 PF08618.10 OEU07125.1 - 0.35 10.1 2.4 0.55 9.4 2.4 1.3 1 0 0 1 1 1 0 Transcription factor Opi1 CDC45 PF02724.14 OEU07125.1 - 0.51 8.6 41.4 0.036 12.4 20.3 2.3 2 0 0 2 2 2 0 CDC45-like protein RR_TM4-6 PF06459.12 OEU07125.1 - 0.79 9.5 26.5 0.49 10.2 13.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 OEU07125.1 - 5.4 7.3 41.4 2.5 8.4 9.6 2.7 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 PNISR PF15996.5 OEU07125.1 - 7.7 6.7 32.2 0.74 10.1 15.8 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR LPMO_10 PF03067.15 OEU07126.1 - 1.5e-05 25.7 0.1 0.0001 23.0 0.1 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Colicin-DNase PF12639.7 OEU07127.1 - 8.3 7.3 7.5 13 6.7 2.2 2.0 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin BORCS8 PF10167.9 OEU07129.1 - 0.062 13.2 1.0 0.13 12.2 1.0 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 RTP PF02334.16 OEU07130.1 - 0.042 14.5 0.2 0.11 13.2 0.2 1.6 1 0 0 1 1 1 0 Replication terminator protein RGI_lyase PF18370.1 OEU07131.1 - 0.11 12.8 0.5 0.11 12.8 0.5 2.0 2 0 0 2 2 2 0 Rhamnogalacturonan I lyases beta-sheet domain Fasciclin PF02469.22 OEU07132.1 - 9.3e-17 61.4 0.0 1.6e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU07132.1 - 5.1e-05 24.0 0.4 0.00038 21.2 0.3 2.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading RNA_helicase PF00910.22 OEU07132.1 - 0.074 13.5 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase ABC_membrane_2 PF06472.15 OEU07132.1 - 0.21 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 DUF4926 PF16277.5 OEU07134.1 - 0.1 11.9 0.7 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) DUF2358 PF10184.9 OEU07135.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) ETRAMP PF09716.10 OEU07135.1 - 1.9 8.6 6.1 10 6.3 0.2 2.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) IBB PF01749.20 OEU07135.1 - 6.2 7.3 7.2 26 5.4 2.6 2.5 1 1 1 2 2 2 0 Importin beta binding domain Neur_chan_memb PF02932.16 OEU07136.1 - 1.8 8.6 4.6 2 8.4 4.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 OEU07136.1 - 9.4 4.9 8.1 11 4.7 8.1 1.1 1 0 0 1 1 1 0 Presenilin Reprolysin_3 PF13582.6 OEU07137.1 - 0.11 13.0 0.5 0.13 12.8 0.5 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like VIGSSK PF14773.6 OEU07140.1 - 0.19 11.8 2.5 0.39 10.9 0.3 2.2 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal TFIIA PF03153.13 OEU07141.1 - 0.0022 18.1 26.5 0.0022 18.1 26.5 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Fez1 PF06818.15 OEU07142.1 - 0.87 10.0 29.8 0.21 12.0 17.9 2.1 1 1 1 2 2 2 0 Fez1 TrbI_Ftype PF09677.10 OEU07142.1 - 1.6 9.1 5.1 0.33 11.3 0.5 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) IMD PF08397.11 OEU07142.1 - 6.1 6.1 17.2 0.61 9.4 12.0 1.9 1 1 1 2 2 2 0 IRSp53/MIM homology domain APG6_N PF17675.1 OEU07142.1 - 7.8 7.0 40.7 0.043 14.4 7.8 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF2316 PF10078.9 OEU07143.1 - 0.093 13.0 1.4 0.19 12.0 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF641 PF04859.12 OEU07143.1 - 0.12 12.7 8.5 0.2 12.0 8.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 OEU07143.1 - 0.17 11.0 8.8 0.23 10.5 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 OEU07143.1 - 2.6 8.4 13.9 3.4 8.0 13.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Myc_N PF01056.18 OEU07143.1 - 4.1 7.2 9.5 7.7 6.3 9.5 1.5 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 OEU07143.1 - 5 7.6 10.1 3.6 8.1 4.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PT PF04886.12 OEU07144.1 - 2.1 8.0 61.4 0.94 9.1 12.8 7.2 2 2 1 3 3 3 0 PT repeat BTB_2 PF02214.22 OEU07146.1 - 1.6e-07 31.6 0.0 5.2e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain SulA PF03846.14 OEU07147.1 - 0.058 13.3 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Cell division inhibitor SulA Capsid_NCLDV PF04451.12 OEU07147.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Asp_protease_2 PF13650.6 OEU07148.1 - 0.0091 16.6 0.0 0.026 15.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease DUF3825 PF12873.7 OEU07148.1 - 0.071 12.6 0.6 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3825) RIO1 PF01163.22 OEU07149.1 - 3e-05 23.7 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OEU07149.1 - 5.8e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OEU07149.1 - 0.022 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Beta-Casp PF10996.8 OEU07149.1 - 0.045 14.0 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Beta-Casp domain WaaY PF06176.11 OEU07149.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ABC1 PF03109.16 OEU07149.1 - 0.091 12.9 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC1 family PI3K_1B_p101 PF10486.9 OEU07149.1 - 0.11 10.3 3.3 0.16 9.7 3.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TctB PF07331.11 OEU07150.1 - 0.66 10.2 4.6 1.5 9.1 1.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Yae1_N PF09811.9 OEU07151.1 - 3e-07 30.0 39.1 2.2 8.1 0.2 11.4 4 3 7 11 11 11 7 Essential protein Yae1, N terminal MspA PF09203.11 OEU07151.1 - 1.2 8.9 9.5 1.6e+03 -1.2 9.5 3.7 1 1 0 1 1 1 0 MspA Rick_17kDa_Anti PF05433.15 OEU07151.1 - 1.5 8.8 40.3 2.3 8.2 1.3 7.0 3 2 5 8 8 8 0 Glycine zipper 2TM domain UPF0016 PF01169.19 OEU07151.1 - 4.4 7.7 16.5 20 5.6 0.2 5.3 1 1 3 5 5 5 0 Uncharacterized protein family UPF0016 DUF4567 PF15131.6 OEU07151.1 - 8 6.6 21.6 32 4.7 0.2 6.4 3 2 4 7 7 7 0 Domain of unknown function (DUF4567) COX6A PF02046.15 OEU07153.1 - 3.4e-07 30.7 0.3 6.9e-07 29.7 0.3 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF5613 PF18467.1 OEU07154.1 - 0.021 15.2 2.9 0.034 14.5 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) Macoilin PF09726.9 OEU07154.1 - 0.8 8.2 5.0 1 7.8 5.0 1.1 1 0 0 1 1 1 0 Macoilin family Transketolase_C PF02780.20 OEU07155.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain Pox_MCEL PF03291.16 OEU07155.1 - 0.053 12.6 3.6 0.046 12.8 1.9 1.6 2 0 0 2 2 2 0 mRNA capping enzyme Spt5_N PF11942.8 OEU07155.1 - 2.8 9.0 6.3 2.9 8.9 0.1 2.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal VWA_2 PF13519.6 OEU07156.1 - 1.7e-09 38.3 0.1 3.1e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5308 PF17233.2 OEU07156.1 - 0.024 14.9 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RXT2_N PF08595.11 OEU07156.1 - 0.27 11.3 18.9 0.023 14.7 9.9 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal V_ATPase_I PF01496.19 OEU07156.1 - 0.32 8.9 4.7 0.47 8.3 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BUD22 PF09073.10 OEU07156.1 - 1.1 8.5 19.5 0.11 11.8 14.8 1.6 2 0 0 2 2 2 0 BUD22 DNA_pol_phi PF04931.13 OEU07156.1 - 3.9 5.5 26.0 7.1 4.6 26.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 OEU07156.1 - 6.8 5.1 14.6 0.48 8.9 8.8 1.8 2 0 0 2 2 2 0 Utp14 protein Hemocyanin_C PF03723.14 OEU07158.1 - 0.019 14.3 0.0 4.3 6.6 0.0 2.1 1 1 1 2 2 2 0 Hemocyanin, ig-like domain SR-25 PF10500.9 OEU07158.1 - 0.74 9.4 8.8 1 8.9 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YcbB PF08664.10 OEU07159.1 - 0.058 13.5 4.7 0.077 13.0 0.2 2.3 1 1 0 2 2 2 0 YcbB domain IF2_N PF04760.15 OEU07159.1 - 0.1 12.4 1.7 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region FliJ PF02050.16 OEU07159.1 - 0.15 12.3 1.6 9.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein BLM10_N PF16547.5 OEU07159.1 - 6.8 7.1 7.3 5.1 7.5 2.0 2.7 2 1 1 3 3 3 0 Proteasome-substrate-size regulator, N-terminal DUF3494 PF11999.8 OEU07161.1 - 2.9e-49 167.5 16.1 3.3e-49 167.4 16.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) SNF2_N PF00176.23 OEU07162.1 - 4.5e-60 203.2 0.9 1.7e-59 201.3 0.9 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OEU07162.1 - 1e-11 45.2 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU07162.1 - 4.3e-07 29.9 0.0 6.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OEU07162.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.5 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 OEU07162.1 - 0.11 12.8 0.0 0.32 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain GIY-YIG PF01541.24 OEU07163.1 - 1.6e-12 47.5 0.1 8e-12 45.3 0.1 2.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain Acetyltransf_9 PF13527.7 OEU07164.1 - 3.8e-09 36.7 0.0 7.7e-08 32.5 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU07164.1 - 0.00018 21.4 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU07164.1 - 0.00036 20.8 0.0 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OEU07164.1 - 0.0012 18.7 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OEU07164.1 - 0.0035 17.7 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PulG PF11773.8 OEU07164.1 - 1.8 8.4 6.2 10 6.0 3.3 2.7 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin AGA2 PF17366.2 OEU07164.1 - 1.8 8.3 5.9 0.22 11.3 0.9 2.0 2 0 0 2 2 2 0 A-agglutinin-binding subunit Aga2 SUIM_assoc PF16619.5 OEU07164.1 - 6.5 6.9 23.5 0.11 12.6 9.1 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 BUD22 PF09073.10 OEU07165.1 - 0.56 9.5 12.3 0.64 9.3 12.3 1.0 1 0 0 1 1 1 0 BUD22 F-protein PF00469.20 OEU07165.1 - 0.92 9.1 4.6 2 7.9 4.6 1.6 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef Secretin_N_2 PF07655.13 OEU07165.1 - 3.8 8.1 14.4 4.7 7.8 6.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain PEPcase PF00311.17 OEU07166.1 - 2.3e-232 773.4 1.4 1.5e-217 724.5 0.3 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 OEU07166.1 - 0.00031 19.4 0.0 0.00051 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Adenylate_cycl PF01295.18 OEU07166.1 - 0.018 13.7 0.1 0.029 13.0 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I DUF677 PF05055.12 OEU07167.1 - 0.033 13.1 1.1 0.049 12.5 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF677) FA_FANCE PF11510.8 OEU07167.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE Tudor_FRX1 PF18336.1 OEU07168.1 - 0.037 13.9 0.3 4.7 7.2 0.1 3.0 3 0 0 3 3 3 0 Fragile X mental retardation Tudor domain Macoilin PF09726.9 OEU07168.1 - 5.4 5.4 12.0 6.2 5.2 8.2 2.1 2 0 0 2 2 2 0 Macoilin family Ank_4 PF13637.6 OEU07169.1 - 0.042 14.4 0.1 0.67 10.6 0.0 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SR-25 PF10500.9 OEU07172.1 - 5.2e-22 78.6 9.7 1.1e-21 77.6 0.3 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Roughex PF06020.11 OEU07172.1 - 0.26 10.3 6.2 0.35 9.9 6.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein FAO_M PF16350.5 OEU07173.1 - 0.032 14.6 0.9 11 6.4 0.0 2.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase central domain PRP3 PF08572.10 OEU07173.1 - 0.28 10.9 16.0 0.55 9.9 0.1 3.2 3 1 0 3 3 3 0 pre-mRNA processing factor 3 (PRP3) LRR_4 PF12799.7 OEU07174.1 - 7.4e-13 48.5 24.2 0.00023 21.4 2.5 5.5 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU07174.1 - 8e-12 44.8 15.6 3.2e-06 26.8 5.8 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 OEU07174.1 - 5.3e-07 29.3 17.1 9.3 7.2 0.0 7.8 7 1 0 7 7 7 5 Leucine Rich Repeat Notch PF00066.17 OEU07174.1 - 0.54 10.8 11.0 0.25 11.8 4.8 2.7 2 0 0 2 2 2 0 LNR domain EMC3_TMCO1 PF01956.16 OEU07175.1 - 0.00097 18.9 0.0 1 9.1 0.0 2.8 2 1 0 3 3 3 2 Integral membrane protein EMC3/TMCO1-like DUF2207 PF09972.9 OEU07175.1 - 0.016 14.0 0.1 0.016 14.0 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Macoilin PF09726.9 OEU07175.1 - 6.7 5.1 24.1 0.023 13.3 10.9 2.2 2 0 0 2 2 2 0 Macoilin family TFIIA PF03153.13 OEU07175.1 - 9.7 6.1 38.0 7 6.5 18.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 OEU07177.1 - 3e-05 23.6 0.6 0.024 14.1 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase Pkinase_Tyr PF07714.17 OEU07178.1 - 2.1e-13 50.2 0.9 1.1e-05 24.9 0.0 3.4 2 2 2 4 4 4 2 Protein tyrosine kinase Pkinase PF00069.25 OEU07178.1 - 1.2e-11 44.5 3.0 4.4e-08 32.8 0.2 3.5 2 2 1 3 3 3 2 Protein kinase domain SPATA3 PF15662.5 OEU07178.1 - 0.0076 16.9 4.4 0.0076 16.9 4.4 2.5 4 0 0 4 4 4 1 Spermatogenesis-associated protein 3 family Herpes_DNAp_acc PF04929.12 OEU07178.1 - 0.45 9.4 6.6 1 8.2 6.6 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2371 PF10177.9 OEU07179.1 - 0.0032 17.7 0.1 0.0047 17.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) Secretin_N_2 PF07655.13 OEU07179.1 - 0.0032 18.0 6.1 0.0032 18.0 6.1 2.2 2 0 0 2 2 2 1 Secretin N-terminal domain MMM1 PF10296.9 OEU07179.1 - 0.0074 15.4 0.6 0.0083 15.2 0.6 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF2749 PF10907.8 OEU07179.1 - 0.015 15.4 0.3 0.031 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF3328 PF11807.8 OEU07179.1 - 0.046 13.5 0.4 0.059 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Zn_peptidase PF04228.13 OEU07179.1 - 0.049 13.1 0.5 0.05 13.1 0.5 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase MID_MedPIWI PF18296.1 OEU07179.1 - 0.15 11.9 4.9 0.17 11.7 4.9 1.1 1 0 0 1 1 1 0 MID domain of medPIWI MPM1 PF17234.2 OEU07179.1 - 1 9.6 7.1 1.1 9.5 6.7 1.4 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SCIMP PF15050.6 OEU07179.1 - 9.3 6.7 8.5 33 4.9 8.5 2.0 1 1 0 1 1 1 0 SCIMP protein DUF285 PF03382.14 OEU07180.1 - 1.9e-89 295.5 65.7 1.7e-34 118.2 20.2 3.1 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 U5_2-snRNA_bdg PF10597.9 OEU07180.1 - 0.00011 22.3 11.5 0.82 9.7 0.2 4.3 1 1 3 4 4 4 3 U5-snRNA binding site 2 of PrP8 Csm2_III-A PF03750.13 OEU07180.1 - 0.0028 18.5 0.4 1.8 9.4 0.0 3.8 1 1 4 5 5 5 1 Csm2 Type III-A T2SSF PF00482.23 OEU07180.1 - 0.011 15.7 0.1 13 5.8 0.0 3.1 1 1 3 4 4 4 0 Type II secretion system (T2SS), protein F NopRA1 PF16201.5 OEU07180.1 - 0.015 14.8 4.5 3.3 7.2 0.1 3.0 2 1 1 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Toxin_YhaV PF11663.8 OEU07180.1 - 0.026 14.6 1.1 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Toxin with endonuclease activity, of toxin-antitoxin system Colicin_immun PF09204.10 OEU07180.1 - 0.042 14.4 7.3 2.1 9.0 0.4 2.9 1 1 1 3 3 3 0 Bacterial self-protective colicin-like immunity Prok_Ub PF14454.6 OEU07180.1 - 0.045 13.4 3.5 2.4 7.9 0.0 4.5 5 0 0 5 5 5 0 Prokaryotic Ubiquitin RraB PF06877.11 OEU07180.1 - 0.13 13.0 1.6 1.4e+02 3.2 0.0 4.4 3 2 1 5 5 5 0 Regulator of ribonuclease activity B Arm_vescicular PF18770.1 OEU07180.1 - 0.6 10.1 14.8 1.1e+02 2.8 0.0 7.7 9 0 0 9 9 9 0 Armadillo tether-repeat of vescicular transport factor Interferon PF00143.19 OEU07180.1 - 1.2 9.3 10.2 7.5 6.7 0.4 3.5 1 1 1 3 3 3 0 Interferon alpha/beta domain Yae1_N PF09811.9 OEU07181.1 - 8.6e-09 35.0 47.2 1.3 8.8 0.3 14.2 1 1 7 11 11 11 9 Essential protein Yae1, N terminal Rick_17kDa_Anti PF05433.15 OEU07181.1 - 2 8.4 45.7 1.7 8.6 11.8 8.4 4 3 6 10 10 10 0 Glycine zipper 2TM domain UQ_con PF00179.26 OEU07182.1 - 1.2e-10 41.2 0.2 2.8e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4_3 PF13920.6 OEU07182.1 - 1.1e-09 37.9 7.9 2.9e-09 36.6 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU07182.1 - 1.2e-09 37.8 10.3 1.2e-09 37.8 10.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU07182.1 - 3e-09 36.6 11.4 3e-09 36.6 11.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU07182.1 - 6.6e-08 32.4 8.9 1.3e-06 28.3 9.8 2.5 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OEU07182.1 - 8.8e-08 31.9 8.4 2.1e-07 30.7 8.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OEU07182.1 - 1.5e-07 31.7 10.5 1.5e-07 31.7 10.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OEU07182.1 - 2e-07 30.8 9.1 5.5e-07 29.4 9.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OEU07182.1 - 3.7e-05 23.5 4.6 0.00012 21.9 4.6 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OEU07182.1 - 0.00018 21.6 10.4 0.00048 20.2 10.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OEU07182.1 - 0.0024 18.1 5.7 0.0024 18.1 5.7 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OEU07182.1 - 0.0028 17.4 9.3 0.0044 16.8 6.8 2.6 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 OEU07182.1 - 0.0083 16.0 6.0 0.029 14.2 6.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OEU07182.1 - 0.0094 16.1 2.4 0.03 14.4 2.4 1.8 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-Nse PF11789.8 OEU07182.1 - 0.015 15.1 6.2 0.015 15.1 6.2 2.7 3 1 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit DUF641 PF04859.12 OEU07182.1 - 0.018 15.4 0.6 0.029 14.7 0.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-ANAPC11 PF12861.7 OEU07182.1 - 0.019 15.0 2.2 0.019 15.0 2.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PKcGMP_CC PF16808.5 OEU07182.1 - 0.14 12.1 1.4 0.3 11.0 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sina PF03145.16 OEU07182.1 - 0.49 10.3 7.1 3.9 7.4 5.6 2.3 1 1 1 2 2 2 0 Seven in absentia protein family ADK_lid PF05191.14 OEU07182.1 - 1.4 8.9 4.7 3.4 7.7 2.4 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_10 PF16685.5 OEU07182.1 - 1.9 8.7 8.7 2.4 8.3 7.1 2.0 2 0 0 2 2 1 0 zinc RING finger of MSL2 Glycos_trans_3N PF02885.17 OEU07183.1 - 0.078 12.8 0.4 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain zf-MYND PF01753.18 OEU07184.1 - 5.3e-05 23.2 11.8 5.3e-05 23.2 11.8 2.3 1 1 1 2 2 2 1 MYND finger Yae1_N PF09811.9 OEU07185.1 - 1.1e-06 28.2 69.8 8.6 6.2 0.1 16.3 4 3 6 10 10 10 1 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU07185.1 - 0.0075 16.4 0.0 6.8 6.8 0.0 4.4 1 1 2 3 3 3 1 Outer membrane protein beta-barrel domain MspA PF09203.11 OEU07185.1 - 0.16 11.8 12.1 3.9e+03 -2.5 12.1 4.8 1 1 0 1 1 1 0 MspA Rick_17kDa_Anti PF05433.15 OEU07185.1 - 1.2 9.1 62.3 0.081 12.8 4.9 7.9 4 2 4 8 8 8 0 Glycine zipper 2TM domain PT PF04886.12 OEU07186.1 - 1.2e-20 72.7 81.0 0.005 16.3 12.1 7.6 1 1 3 4 4 4 3 PT repeat PT PF04886.12 OEU07187.1 - 4.1e-07 29.4 33.3 0.00022 20.7 14.9 2.4 1 1 1 2 2 2 2 PT repeat FHA PF00498.26 OEU07189.1 - 3e-06 27.5 0.1 9.3e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 FHA domain YL1 PF05764.13 OEU07189.1 - 0.00017 21.8 2.9 0.00017 21.8 2.9 2.2 2 0 0 2 2 2 1 YL1 nuclear protein WBP-1 PF11669.8 OEU07189.1 - 0.053 14.2 0.1 0.28 11.8 0.0 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 Clathrin_propel PF01394.20 OEU07189.1 - 0.1 13.0 0.0 0.36 11.2 0.0 2.0 1 0 0 1 1 1 0 Clathrin propeller repeat DUF4611 PF15387.6 OEU07189.1 - 7.4 6.9 17.1 7.6 6.8 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF2379 PF09543.10 OEU07190.1 - 0.05 13.8 0.2 0.066 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Spem1 PF15670.5 OEU07192.1 - 5.8e-05 22.8 5.7 5.8e-05 22.8 5.7 1.7 2 0 0 2 2 2 1 Spermatid maturation protein 1 DUF2572 PF10833.8 OEU07192.1 - 0.95 9.2 7.1 2 8.1 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Miga PF10265.9 OEU07192.1 - 6.6 5.6 19.3 0.02 13.9 3.8 2.5 2 1 0 2 2 2 0 Mitoguardin MnmE_helical PF12631.7 OEU07194.1 - 0.0074 16.5 1.4 0.013 15.7 1.4 1.3 1 0 0 1 1 1 1 MnmE helical domain Retrotran_gag_2 PF14223.6 OEU07194.1 - 0.074 12.7 8.0 0.074 12.7 0.1 2.7 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type BLOC1_2 PF10046.9 OEU07194.1 - 0.075 13.3 7.1 0.25 11.7 2.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 eIF3_N PF09440.10 OEU07194.1 - 1.8 9.0 8.4 16 6.0 2.9 2.6 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain Med9 PF07544.13 OEU07194.1 - 2.7 8.1 6.3 23 5.1 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1104 PF06518.11 OEU07194.1 - 9.7 6.6 11.5 4.5 7.7 4.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) PPTA PF01239.22 OEU07197.1 - 0.00011 21.8 0.1 0.00011 21.8 0.1 3.1 4 0 0 4 4 4 1 Protein prenyltransferase alpha subunit repeat BTG PF07742.12 OEU07197.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 BTG family SCHIP-1 PF10148.9 OEU07197.1 - 0.18 11.4 6.4 0.11 12.1 2.3 2.4 1 1 1 2 2 2 0 Schwannomin-interacting protein 1 Dicty_REP PF05086.12 OEU07198.1 - 0.0014 16.8 12.7 0.0014 16.8 12.7 2.0 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein BSP_II PF05432.11 OEU07198.1 - 0.0021 17.8 21.3 0.0021 17.8 21.3 2.8 4 0 0 4 4 4 1 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.6 OEU07198.1 - 2.7 8.4 24.9 2.7 8.4 1.3 4.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Menin PF05053.13 OEU07198.1 - 5.2 5.3 10.1 0.34 9.2 3.8 1.9 2 0 0 2 2 2 0 Menin DUF507 PF04368.13 OEU07200.1 - 0.68 9.8 6.9 0.13 12.2 2.7 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF507) SLIDE PF09111.10 OEU07200.1 - 0.9 9.6 4.8 2.4 8.2 0.1 3.1 3 1 1 4 4 4 0 SLIDE Use1 PF09753.9 OEU07203.1 - 1.6e-10 41.1 9.0 1.6e-10 41.1 9.0 3.7 3 1 0 4 4 4 1 Membrane fusion protein Use1 Ank_2 PF12796.7 OEU07203.1 - 5.6e-08 33.3 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU07203.1 - 1.1e-07 32.2 0.1 2.9e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU07203.1 - 2.3e-06 27.8 0.0 6.7e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU07203.1 - 4.3e-05 23.8 0.0 8.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 OEU07203.1 - 0.00012 22.2 0.0 0.00053 20.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat DUF3439 PF11921.8 OEU07203.1 - 0.013 15.5 0.4 0.035 14.1 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SNARE PF05739.19 OEU07203.1 - 0.062 13.3 0.1 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 SNARE domain Mucin PF01456.17 OEU07203.1 - 1.9 8.5 13.4 0.041 13.9 3.3 2.8 3 0 0 3 3 3 0 Mucin-like glycoprotein SRP_SPB PF02978.19 OEU07205.1 - 0.045 14.4 0.4 0.12 13.0 0.2 1.7 1 1 1 2 2 2 0 Signal peptide binding domain DUF4070 PF13282.6 OEU07205.1 - 0.078 13.1 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) SR-25 PF10500.9 OEU07207.1 - 7 6.2 24.7 0.55 9.8 1.9 2.7 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein PRANC PF09372.10 OEU07208.1 - 2.3e-05 24.6 0.5 6.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 PRANC domain MMPL PF03176.15 OEU07208.1 - 0.048 12.6 0.2 0.059 12.3 0.2 1.1 1 0 0 1 1 1 0 MMPL family Methyltransf_32 PF13679.6 OEU07209.1 - 9.7e-08 32.1 5.3 9.7e-08 32.1 5.3 2.7 2 2 0 2 2 2 1 Methyltransferase domain Pro-rich PF15240.6 OEU07209.1 - 0.0068 16.7 2.7 0.021 15.1 2.7 1.8 1 0 0 1 1 1 1 Proline-rich Adaptin_binding PF10199.9 OEU07209.1 - 0.023 15.3 2.9 0.023 15.3 2.9 3.2 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RNA_pol_Rpc4 PF05132.14 OEU07209.1 - 0.4 11.1 8.4 3.1 8.2 3.0 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Serinc PF03348.15 OEU07209.1 - 2.2 7.1 9.5 0.08 11.9 2.5 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) Methyltransf_16 PF10294.9 OEU07212.1 - 5.3e-19 68.6 0.8 9.2e-19 67.8 0.8 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 OEU07212.1 - 0.00039 20.3 0.2 0.00059 19.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU07212.1 - 0.00051 19.5 0.8 0.00081 18.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU07212.1 - 0.007 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OEU07212.1 - 0.042 14.6 3.4 0.45 11.3 0.2 2.6 3 0 0 3 3 3 0 Methyltransferase domain Yae1_N PF09811.9 OEU07213.1 - 3.4e-13 49.0 69.1 0.058 13.1 0.6 14.8 5 3 7 12 12 12 11 Essential protein Yae1, N terminal MspA PF09203.11 OEU07213.1 - 4.7 7.0 6.8 1.3e+03 -1.0 6.8 3.7 1 1 0 1 1 1 0 MspA PT PF04886.12 OEU07214.1 - 1.6e-10 40.3 17.2 3.5e-05 23.2 9.4 2.4 1 1 1 2 2 2 2 PT repeat HA PF03457.14 OEU07216.1 - 4.7e-21 74.9 1.5 5.3e-21 74.7 1.5 1.0 1 0 0 1 1 1 1 Helicase associated domain HA PF03457.14 OEU07218.1 - 2.4e-50 168.7 5.3 9.1e-21 74.0 0.2 3.0 3 0 0 3 3 3 3 Helicase associated domain Ntox50 PF15542.6 OEU07218.1 - 0.0096 16.7 0.9 5.7 7.8 0.0 2.8 2 1 0 3 3 3 2 Bacterial toxin 50 DUF3836 PF12930.7 OEU07218.1 - 0.032 14.0 6.2 0.84 9.4 1.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF3836) PMR5N PF14416.6 OEU07218.1 - 0.042 14.2 0.6 30 5.0 0.0 3.7 4 0 0 4 4 4 0 PMR5 N terminal Domain Lig_C PF18330.1 OEU07218.1 - 0.14 12.2 0.2 4 7.4 0.1 2.0 2 0 0 2 2 2 0 Ligase Pab1020 C-terminal region PTPRCAP PF15713.5 OEU07219.1 - 0.035 14.4 1.7 0.035 14.4 1.7 3.1 4 0 0 4 4 4 0 Protein tyrosine phosphatase receptor type C-associated Pex14_N PF04695.13 OEU07219.1 - 0.22 12.2 14.3 0.046 14.4 6.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 OEU07219.1 - 1.2 8.1 16.1 0.024 13.8 8.1 1.9 2 0 0 2 2 2 0 Drosophila roughex protein SUIM_assoc PF16619.5 OEU07219.1 - 4.5 7.4 12.5 0.25 11.4 6.9 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CPSF100_C PF13299.6 OEU07219.1 - 5.6 7.1 6.2 2.7 8.1 0.9 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal 7TM_GPCR_Srab PF10292.9 OEU07220.1 - 0.18 10.7 1.4 0.32 9.9 1.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor SUIM_assoc PF16619.5 OEU07220.1 - 1.6 8.9 16.5 0.47 10.6 2.0 3.1 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 OEU07221.1 - 0.018 13.7 6.4 0.02 13.5 6.4 1.3 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OEU07221.1 - 0.1 12.2 10.5 0.15 11.6 10.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 OEU07221.1 - 1.4 7.1 14.7 1.9 6.6 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SCIMP PF15050.6 OEU07221.1 - 5.4 7.5 7.1 3.3 8.2 5.1 1.7 1 1 0 1 1 1 0 SCIMP protein FAM60A PF15396.6 OEU07221.1 - 9.9 6.1 8.7 0.92 9.5 3.9 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Ank_5 PF13857.6 OEU07222.1 - 0.00052 20.3 1.4 0.002 18.4 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU07222.1 - 0.0022 18.5 0.5 0.76 10.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU07222.1 - 0.012 16.1 0.2 0.66 10.7 0.1 3.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 OEU07222.1 - 0.023 15.3 0.1 0.12 12.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 OEU07222.1 - 0.086 13.3 0.6 0.39 11.2 0.2 2.3 2 0 0 2 2 2 0 Ankyrin repeat Thioredoxin_16 PF18569.1 OEU07225.1 - 0.09 12.9 0.2 0.5 10.5 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin-like domain LRR_4 PF12799.7 OEU07225.1 - 3.6 8.1 7.4 4.5 7.8 4.3 2.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Cyclin_N PF00134.23 OEU07227.1 - 1.3e-35 121.9 0.3 2.4e-35 121.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU07227.1 - 1.9e-18 66.7 0.4 3.1e-18 66.0 0.4 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF563 PF04577.14 OEU07228.1 - 1.2e-06 28.9 0.3 5.7e-05 23.4 0.0 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF563) Chloroa_b-bind PF00504.21 OEU07230.1 - 1.2e-42 146.2 0.0 1.6e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein BAT2_N PF07001.11 OEU07231.1 - 0.049 14.1 2.4 0.059 13.8 2.4 1.2 1 0 0 1 1 1 0 BAT2 N-terminus zf-MYND PF01753.18 OEU07232.1 - 4.4e-07 29.9 20.0 1.3e-06 28.4 20.0 1.8 1 0 0 1 1 1 1 MYND finger DnaJ PF00226.31 OEU07233.1 - 0.00045 20.3 0.1 0.00078 19.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Spermine_synth PF01564.17 OEU07234.1 - 2.9e-14 52.9 0.6 5.3e-14 52.1 0.6 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain SET PF00856.28 OEU07234.1 - 9.7e-09 35.8 0.1 1.2e-07 32.3 0.1 2.6 2 1 0 2 2 2 1 SET domain AdoMet_dc PF02675.15 OEU07234.1 - 4.3e-07 30.1 0.1 1.6e-06 28.3 0.1 2.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Methyltransf_12 PF08242.12 OEU07234.1 - 0.014 16.1 0.0 0.054 14.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OEU07234.1 - 0.11 13.1 0.1 0.62 10.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Dirigent PF03018.14 OEU07235.1 - 0.1 12.4 1.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Dirigent-like protein Ank_2 PF12796.7 OEU07236.1 - 2.5e-08 34.4 0.9 0.0014 19.2 0.2 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU07236.1 - 2.2e-06 28.1 1.2 0.0068 17.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DnaJ PF00226.31 OEU07236.1 - 9e-05 22.5 0.1 0.0009 19.3 0.0 2.6 2 0 0 2 2 2 1 DnaJ domain Ank_3 PF13606.6 OEU07236.1 - 0.00043 20.5 0.0 0.28 11.8 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OEU07236.1 - 0.00058 20.1 0.1 1.4 9.3 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) PBP1_TM PF14812.6 OEU07236.1 - 0.0007 19.9 27.4 0.0046 17.3 4.6 4.7 4 0 0 4 4 4 2 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 OEU07236.1 - 0.2 11.9 0.2 0.2 11.9 0.2 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) GEN1_C PF18380.1 OEU07236.1 - 0.93 10.4 0.0 0.93 10.4 0.0 4.5 5 0 0 5 5 5 0 Holliday junction resolvase Gen1 C-terminal domain Beta-lactamase PF00144.24 OEU07237.1 - 4.3e-09 36.1 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_1 PF00583.25 OEU07238.1 - 3.1e-06 27.4 0.0 0.00034 20.8 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU07238.1 - 0.00013 22.3 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU07238.1 - 0.00024 21.0 0.0 0.00059 19.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU07238.1 - 0.00092 19.1 0.0 0.11 12.5 0.0 2.5 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_15 PF17013.5 OEU07238.1 - 0.023 14.1 2.3 0.035 13.6 2.3 1.7 1 1 0 1 1 1 0 Putative acetyl-transferase Rhamno_transf PF11316.8 OEU07239.1 - 0.66 9.3 3.6 1.2 8.5 3.6 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase PseudoU_synth_2 PF00849.22 OEU07240.1 - 2.2e-16 60.3 0.5 1.2e-15 57.9 0.0 2.5 2 1 0 2 2 2 1 RNA pseudouridylate synthase Ago_N_1 PF18351.1 OEU07240.1 - 0.38 11.2 3.8 0.29 11.6 0.4 2.6 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain Amidoligase_2 PF12224.8 OEU07242.1 - 7.9e-21 74.9 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Pox_A22 PF04848.13 OEU07242.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A22 protein DUF629 PF04780.12 OEU07243.1 - 0.021 13.4 0.1 0.038 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Arm PF00514.23 OEU07243.1 - 0.088 12.9 0.1 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TPR_2 PF07719.17 OEU07244.1 - 0.0011 18.9 0.6 0.0025 17.8 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU07244.1 - 0.0042 16.8 0.5 0.0083 15.9 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU07244.1 - 0.0099 16.0 0.2 0.023 14.9 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU07244.1 - 0.032 14.2 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OEU07244.1 - 0.053 13.6 1.5 0.14 12.2 1.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Macoilin PF09726.9 OEU07244.1 - 0.053 12.1 16.4 0.057 12.0 16.4 1.1 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 OEU07244.1 - 0.1 12.5 4.3 0.21 11.5 4.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family BRF1 PF07741.13 OEU07244.1 - 0.79 10.1 10.6 2.1 8.7 2.4 2.4 1 1 1 2 2 2 0 Brf1-like TBP-binding domain PRKG1_interact PF15898.5 OEU07244.1 - 1 10.3 11.7 11 6.9 6.5 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4639 PF15479.6 OEU07244.1 - 1.2 8.0 7.6 1.4 7.8 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) SR-25 PF10500.9 OEU07244.1 - 1.2 8.7 28.6 4.8 6.7 28.2 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein MRI PF15325.6 OEU07244.1 - 4.3 8.5 7.9 2.9 9.0 3.5 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection TCP PF03634.13 OEU07244.1 - 9.1 6.8 19.7 4.6 7.8 12.8 2.1 2 0 0 2 2 2 0 TCP family transcription factor zf-MYND PF01753.18 OEU07249.1 - 3e-10 40.0 13.6 4.9e-10 39.3 13.6 1.4 1 0 0 1 1 1 1 MYND finger MinE PF03776.14 OEU07249.1 - 0.23 11.5 4.5 0.49 10.4 4.4 1.6 1 1 0 1 1 1 0 Septum formation topological specificity factor MinE SPT16 PF08644.11 OEU07249.1 - 1.6 8.9 7.4 3.1 7.9 7.4 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) zf-Mss51 PF13824.6 OEU07249.1 - 1.8 8.7 9.4 15 5.8 9.6 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CENP-P PF13096.6 OEU07250.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P UN_NPL4 PF11543.8 OEU07251.1 - 2.4e-05 24.7 0.1 0.013 16.0 0.0 2.9 2 0 0 2 2 2 2 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 OEU07251.1 - 0.031 14.0 2.0 4 7.3 0.0 3.7 3 1 0 3 3 3 0 Ubiquitin family BTB PF00651.31 OEU07252.1 - 3e-11 43.5 1.5 6.5e-10 39.2 0.1 2.4 1 1 1 2 2 2 1 BTB/POZ domain SAP PF02037.27 OEU07252.1 - 0.023 14.5 0.1 0.077 12.8 0.0 1.9 2 0 0 2 2 2 0 SAP domain HA PF03457.14 OEU07253.1 - 1.7e-55 185.2 1.2 6.9e-19 68.0 0.1 3.0 3 0 0 3 3 3 3 Helicase associated domain Ribosomal_L7Ae PF01248.26 OEU07253.1 - 0.0019 17.9 0.0 0.42 10.4 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Bystin PF05291.11 OEU07253.1 - 0.11 11.8 1.8 1 8.5 0.1 2.3 2 1 0 2 2 2 0 Bystin HA PF03457.14 OEU07254.1 - 5.1e-14 52.4 0.2 1.2e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain ESCRT-II PF05871.12 OEU07255.1 - 2.3e-40 138.1 0.1 2.8e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit OrgA_MxiK PF09482.10 OEU07255.1 - 0.076 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) HA PF03457.14 OEU07256.1 - 4.7e-38 129.3 0.1 1.7e-18 66.7 0.0 2.0 2 0 0 2 2 2 2 Helicase associated domain CreA PF05981.12 OEU07257.1 - 3.6e-30 104.6 0.0 4.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 CreA protein Dirigent PF03018.14 OEU07258.1 - 0.0092 15.8 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Dirigent-like protein Cu-oxidase_3 PF07732.15 OEU07259.1 - 6.2e-10 39.1 0.1 0.0015 18.6 0.0 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OEU07259.1 - 6.8e-07 29.1 1.6 0.094 12.5 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase DUF1459 PF07312.11 OEU07259.1 - 0.062 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) bMG5 PF17972.1 OEU07259.1 - 2.9 8.3 4.3 2.1 8.7 1.6 1.9 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG5 domain TAF4 PF05236.14 OEU07260.1 - 0.003 17.4 12.7 0.003 17.4 12.7 2.2 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF4569 PF15133.6 OEU07260.1 - 0.0084 15.9 10.9 0.0084 15.9 10.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4569) MDM1 PF15501.6 OEU07260.1 - 0.5 9.5 23.3 1.7 7.7 15.6 2.2 2 0 0 2 2 2 0 Nuclear protein MDM1 Caldesmon PF02029.15 OEU07260.1 - 1.5 7.5 29.0 3.6 6.2 28.7 1.9 1 1 0 1 1 1 0 Caldesmon VIT1 PF01988.19 OEU07260.1 - 6.5 6.6 5.3 58 3.5 6.6 1.8 2 0 0 2 2 2 0 VIT family DUF4578 PF15147.6 OEU07261.1 - 0.016 16.1 1.6 0.027 15.3 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) RPN13_C PF16550.5 OEU07261.1 - 0.2 11.9 4.4 0.21 11.7 3.3 1.6 2 0 0 2 2 2 0 UCH-binding domain DUF2798 PF11391.8 OEU07261.1 - 8 6.6 7.6 19 5.4 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Trs65 PF12735.7 OEU07262.1 - 0.0089 15.5 0.7 0.036 13.5 0.2 1.9 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 PIG-Y PF15159.6 OEU07262.1 - 0.86 10.6 5.5 0.16 12.9 0.5 2.6 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PLDc_2 PF13091.6 OEU07264.1 - 1.4e-12 47.7 0.0 4.2e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OEU07264.1 - 0.0028 17.8 7.9 0.25 11.6 0.0 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif RusA PF05866.11 OEU07265.1 - 3.6e-10 40.4 1.0 3.6e-10 40.4 1.0 2.2 2 0 0 2 2 2 1 Endodeoxyribonuclease RusA LRR_4 PF12799.7 OEU07266.1 - 1.1e-20 73.4 33.0 0.00023 21.5 2.5 6.7 4 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU07266.1 - 3e-19 68.5 34.8 8.7e-06 25.4 1.8 5.4 2 2 1 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 OEU07266.1 - 0.0018 18.6 31.0 40 5.3 0.1 11.2 12 0 0 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU07266.1 - 4 7.7 27.3 54 4.2 0.0 9.3 10 0 0 10 10 10 0 Leucine Rich repeat RtcR PF06956.11 OEU07267.1 - 0.096 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Acetyltransf_10 PF13673.7 OEU07268.1 - 8.1e-06 25.8 0.2 2.3e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU07268.1 - 0.00052 20.2 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU07268.1 - 0.017 15.6 0.3 0.033 14.6 0.3 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU07268.1 - 0.035 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein DUF4174 PF13778.6 OEU07269.1 - 0.048 14.1 0.1 0.49 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) DUF1292 PF06949.11 OEU07269.1 - 0.094 13.7 0.1 0.23 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) DUF1673 PF07895.11 OEU07270.1 - 1.3 8.7 6.2 7.8 6.1 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1673) Utp14 PF04615.13 OEU07271.1 - 9.5 4.6 37.0 0.18 10.3 30.2 1.5 2 0 0 2 2 2 0 Utp14 protein Methyltransf_16 PF10294.9 OEU07272.1 - 2.8e-14 53.2 0.1 5.7e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase zf-CCHC PF00098.23 OEU07272.1 - 3.4e-05 23.7 1.0 8.6e-05 22.4 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OEU07272.1 - 0.0018 18.2 0.2 0.0046 16.9 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.14 OEU07272.1 - 0.0069 16.1 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_5 PF14787.6 OEU07272.1 - 0.025 14.3 0.3 0.063 13.0 0.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 OEU07272.1 - 0.15 11.8 1.5 0.57 10.0 1.5 2.1 1 0 0 1 1 1 0 Zinc knuckle 3H PF02829.14 OEU07272.1 - 1.5 9.1 3.5 7.7 6.9 0.1 3.7 4 2 2 6 6 6 0 3H domain DUF285 PF03382.14 OEU07273.1 - 4.8e-82 271.7 35.4 7.6e-31 106.4 11.5 3.1 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 p450 PF00067.22 OEU07274.1 - 1.7e-25 89.7 0.0 2e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Apis_Csd PF11671.8 OEU07276.1 - 0.0027 17.7 0.9 0.0047 17.0 0.9 1.4 1 0 0 1 1 1 1 Complementary sex determiner protein HSF_DNA-bind PF00447.17 OEU07277.1 - 8.9e-16 58.3 0.1 9.9e-16 58.1 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding YadA_head PF05658.14 OEU07278.1 - 0.00011 22.5 0.4 0.00011 22.5 0.4 2.9 3 0 0 3 3 3 1 Head domain of trimeric autotransporter adhesin SnAC PF14619.6 OEU07279.1 - 1.8 9.2 6.8 1.9 9.1 0.3 3.0 2 1 1 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex zf-RING_2 PF13639.6 OEU07281.1 - 5.1e-08 33.1 2.8 1.1e-07 32.1 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU07281.1 - 5.9e-06 25.9 3.5 1.4e-05 24.7 2.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU07281.1 - 0.00059 19.7 5.0 0.00086 19.1 3.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OEU07281.1 - 0.00098 19.3 4.6 0.0024 18.0 4.6 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU07281.1 - 0.0016 18.4 4.5 0.0035 17.3 4.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OEU07281.1 - 0.0025 17.6 1.2 0.0025 17.6 1.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU07281.1 - 0.004 17.4 4.7 0.017 15.4 4.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 OEU07281.1 - 0.0044 16.9 5.1 0.059 13.3 1.2 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 OEU07281.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.29 OEU07281.1 - 0.047 13.6 3.5 0.16 11.9 3.5 2.0 1 1 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 OEU07281.1 - 0.15 12.1 3.6 1.1 9.3 3.7 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OEU07281.1 - 0.2 11.5 4.9 20 5.1 4.9 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain YfhO PF09586.10 OEU07281.1 - 0.3 9.3 4.2 0.39 8.9 4.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO zf-C3H2C3 PF17122.5 OEU07281.1 - 0.69 10.0 4.6 0.69 10.0 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger zf-HC5HC2H PF13771.6 OEU07281.1 - 0.89 9.9 7.6 1.5 9.2 6.0 2.2 2 1 0 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 OEU07281.1 - 2.7 7.9 9.0 19 5.2 9.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trypsin_2 PF13365.6 OEU07283.1 - 1.9e-08 35.3 0.0 9e-07 29.9 0.0 2.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OEU07283.1 - 0.00026 20.9 0.0 0.00095 19.0 0.0 1.9 2 0 0 2 2 2 1 Trypsin SDA1 PF05285.12 OEU07283.1 - 3 7.2 22.6 3 7.2 14.7 2.1 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 OEU07283.1 - 3.5 6.9 23.2 0.8 9.0 2.8 2.1 2 0 0 2 2 2 0 BUD22 DUF2457 PF10446.9 OEU07283.1 - 9.2 5.3 33.2 1.8 7.6 25.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF3494 PF11999.8 OEU07284.1 - 8.2e-59 198.7 17.3 1.1e-58 198.3 17.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF3993 PF13158.6 OEU07285.1 - 0.055 13.7 0.4 0.12 12.6 0.1 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3993) YL1 PF05764.13 OEU07285.1 - 0.12 12.4 24.2 0.16 12.1 24.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1045 PF06299.12 OEU07285.1 - 0.4 10.6 4.4 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) AAA_21 PF13304.6 OEU07285.1 - 0.86 9.3 5.5 1.1 9.0 5.5 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Yae1_N PF09811.9 OEU07286.1 - 0.036 13.8 31.9 8.2 6.2 0.2 9.6 4 2 5 9 9 9 0 Essential protein Yae1, N terminal DUF697 PF05128.12 OEU07286.1 - 2.4 7.8 4.9 17 5.1 0.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF697) Transgly_assoc PF04226.13 OEU07286.1 - 4.1 7.7 14.0 24 5.3 0.2 5.4 2 2 1 3 3 3 0 Transglycosylase associated protein GST_C_2 PF13410.6 OEU07287.1 - 2.3e-10 40.4 0.0 4.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU07287.1 - 2.6e-08 34.0 0.0 6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU07287.1 - 7.7e-08 32.4 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OEU07287.1 - 1.3e-06 29.0 0.0 5.9e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF5398 PF17376.2 OEU07287.1 - 0.11 13.1 0.0 0.42 11.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5398) GAGBD PF16828.5 OEU07287.1 - 0.14 12.2 1.8 0.81 9.8 0.2 2.5 2 1 0 2 2 2 0 GAG-binding domain on surface antigen BTB_2 PF02214.22 OEU07288.1 - 2.6e-08 34.1 0.2 4.5e-07 30.1 0.2 2.6 1 1 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU07288.1 - 0.0034 17.5 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF5595 PF18077.1 OEU07288.1 - 0.022 14.8 1.9 0.047 13.8 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) FAM60A PF15396.6 OEU07289.1 - 0.28 11.2 4.3 0.36 10.8 4.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Bromodomain PF00439.25 OEU07291.1 - 4.2e-10 39.6 0.0 4.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Bromodomain TPR_1 PF00515.28 OEU07292.1 - 3.5e-11 42.4 0.3 0.013 15.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat DnaJ PF00226.31 OEU07292.1 - 2.9e-09 36.9 4.2 3.7e-09 36.6 0.5 2.8 2 1 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 OEU07292.1 - 6.1e-08 32.2 6.3 0.07 13.3 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat ShK PF01549.24 OEU07292.1 - 1.1e-06 29.0 1.7 2.8e-06 27.8 1.7 1.7 1 0 0 1 1 1 1 ShK domain-like TPR_12 PF13424.6 OEU07292.1 - 3.7e-06 27.1 0.3 0.013 15.8 0.1 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU07292.1 - 1.6e-05 25.5 0.1 0.081 13.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU07292.1 - 0.0001 22.8 5.8 0.77 10.7 0.1 4.9 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU07292.1 - 0.0016 18.5 7.6 0.51 10.7 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU07292.1 - 0.0022 17.6 0.2 3.4 7.4 0.0 3.4 3 0 0 3 3 3 1 TPR repeat DUF2362 PF10154.9 OEU07292.1 - 0.0024 16.9 0.5 0.0046 16.0 0.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) TPR_6 PF13174.6 OEU07292.1 - 0.0026 18.3 3.9 7.1 7.5 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU07292.1 - 0.0027 18.2 5.8 9.7 6.8 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU07292.1 - 0.003 17.5 0.6 20 5.5 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2229 PF09989.9 OEU07292.1 - 0.1 12.2 2.7 0.49 10.0 0.6 2.5 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) HA PF03457.14 OEU07294.1 - 1.7e-96 316.5 21.9 1.6e-22 79.6 1.1 5.1 5 0 0 5 5 5 5 Helicase associated domain Antirestrict PF03230.13 OEU07294.1 - 3.3e-05 23.8 0.7 27 4.9 0.0 5.1 5 0 0 5 5 5 0 Antirestriction protein PMR5N PF14416.6 OEU07294.1 - 0.00038 20.7 1.8 29 5.1 0.0 5.3 5 0 0 5 5 5 0 PMR5 N terminal Domain Osteopontin PF00865.18 OEU07294.1 - 0.48 9.9 8.5 0.83 9.1 8.5 1.3 1 0 0 1 1 1 0 Osteopontin eIF3_N PF09440.10 OEU07294.1 - 0.9 10.0 3.5 7.7 7.0 0.1 3.1 3 1 0 3 3 3 0 eIF3 subunit 6 N terminal domain protein_MS5 PF04776.12 OEU07294.1 - 1.1 9.4 8.2 6.5 6.9 0.4 3.5 3 1 1 4 4 4 0 Protein MS5 PHINT_rpt PF14882.6 OEU07294.1 - 3.2 8.1 6.6 42 4.5 0.2 4.1 4 0 0 4 4 4 0 Phage-integrase repeat unit Cation_efflux PF01545.21 OEU07295.1 - 5.3e-41 140.6 10.0 8.1e-41 139.9 10.0 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OEU07295.1 - 0.00027 21.0 2.0 0.0005 20.1 0.2 2.3 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter PAT1 PF09770.9 OEU07296.1 - 0.49 8.6 31.1 0.21 9.8 26.5 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Rotamase PF00639.21 OEU07298.1 - 7.8e-16 58.8 0.0 1.3e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OEU07298.1 - 9.1e-14 52.0 0.0 1.2e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU07298.1 - 0.0024 18.7 0.0 0.0035 18.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain HA PF03457.14 OEU07299.1 - 3.3e-44 149.0 9.9 3.8e-17 62.4 0.4 3.6 4 0 0 4 4 4 3 Helicase associated domain NAD_binding_8 PF13450.6 OEU07302.1 - 6.3e-06 26.3 0.0 5.4e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU07302.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OEU07302.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU07302.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_4 PF08007.12 OEU07303.1 - 2.5e-27 96.2 0.0 3.3e-27 95.8 0.0 1.2 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU07303.1 - 0.00013 21.8 0.0 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.19 OEU07303.1 - 0.0053 16.7 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 OEU07303.1 - 0.066 12.9 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Cupin domain cNMP_binding PF00027.29 OEU07305.1 - 9.8e-17 60.8 0.0 1.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Bestrophin PF01062.21 OEU07305.1 - 9.3e-13 48.2 0.1 1.8e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aa_trans PF01490.18 OEU07306.1 - 1.1e-41 142.9 29.5 1.4e-41 142.6 29.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-met PF12874.7 OEU07308.1 - 5.8e-08 32.9 10.2 0.0026 18.1 1.1 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OEU07308.1 - 4.9e-07 29.6 8.1 7.7e-05 22.6 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OEU07308.1 - 8.4e-07 29.1 6.7 5.5e-05 23.4 0.5 4.5 6 0 0 6 6 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OEU07308.1 - 1e-06 28.8 10.5 0.019 15.4 1.0 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 OEU07308.1 - 8.2e-06 26.0 5.6 0.013 15.7 0.3 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OEU07308.1 - 9.1e-05 22.6 5.3 0.023 15.0 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OEU07308.1 - 0.00017 22.1 6.7 0.0036 18.0 0.6 4.5 6 0 0 6 6 3 2 C2H2-type zinc finger Stc1 PF12898.7 OEU07308.1 - 0.00078 19.9 2.7 0.00078 19.9 2.7 3.4 2 1 1 3 3 3 1 Stc1 domain zf_UBZ PF18439.1 OEU07308.1 - 0.0051 16.4 5.3 0.36 10.5 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OEU07308.1 - 0.0087 16.2 1.1 0.0087 16.2 1.1 3.9 4 1 0 4 4 4 1 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 OEU07308.1 - 0.017 14.7 5.0 0.39 10.4 0.2 2.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 OEU07308.1 - 0.02 14.6 1.0 0.02 14.6 1.0 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OEU07308.1 - 0.18 12.2 11.1 1.2 9.5 0.1 3.6 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 OEU07308.1 - 0.35 11.6 7.0 7.3 7.3 0.4 2.5 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 OEU07308.1 - 0.62 10.1 7.4 11 6.1 0.1 3.0 2 1 0 2 2 2 0 CpXC protein zf-C2H2_9 PF16293.5 OEU07308.1 - 0.65 9.9 4.0 17 5.3 0.3 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) HypA PF01155.19 OEU07308.1 - 1.1 9.3 10.6 0.36 10.9 1.1 3.1 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Evr1_Alr PF04777.13 OEU07308.1 - 1.3 9.6 6.5 4.2 7.9 0.3 2.8 3 0 0 3 3 3 0 Erv1 / Alr family zf-C2HC_2 PF13913.6 OEU07308.1 - 1.7 8.6 10.1 1.7 8.6 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Ribosomal_L29 PF00831.23 OEU07309.1 - 0.17 11.9 5.0 0.44 10.6 0.1 3.3 1 1 0 2 2 2 0 Ribosomal L29 protein TSC22 PF01166.18 OEU07309.1 - 0.61 10.4 5.5 0.57 10.5 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family TCR PF03638.15 OEU07310.1 - 1.7e-19 69.9 47.7 1.1e-09 38.4 27.1 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Gly_transf_sug PF04488.15 OEU07311.1 - 1.8e-10 41.3 0.5 4.2e-10 40.1 0.5 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU07311.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Aldo_ket_red PF00248.21 OEU07312.1 - 4.5e-71 239.4 0.0 5.7e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SASA PF03629.18 OEU07313.1 - 5.7e-14 52.3 0.2 4.4e-07 29.8 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase DUF4131 PF13567.6 OEU07313.1 - 0.1 12.3 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 OEU07314.1 - 2.2e-22 79.5 32.2 2.2e-22 79.5 32.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily SAP PF02037.27 OEU07315.1 - 9.9e-11 41.1 11.5 8.2e-06 25.4 1.1 2.6 3 0 0 3 3 3 2 SAP domain EVI2A PF05399.11 OEU07316.1 - 0.19 11.3 5.3 0.24 11.0 4.8 1.4 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Mito_fiss_reg PF05308.11 OEU07316.1 - 0.38 10.8 3.3 0.54 10.3 3.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CTP_transf_1 PF01148.20 OEU07317.1 - 4.6e-43 147.9 15.4 6.5e-43 147.4 15.4 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family MFS_1 PF07690.16 OEU07318.1 - 4.6e-31 108.0 23.9 5.3e-22 78.2 7.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU07318.1 - 0.00026 20.0 15.7 0.00026 20.0 15.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF5551 PF17705.1 OEU07318.1 - 0.07 12.8 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5551) DUF1823 PF08853.11 OEU07319.1 - 3.7e-40 136.6 1.0 4.3e-40 136.4 0.5 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1823) HA PF03457.14 OEU07320.1 - 2e-57 191.4 5.2 2.8e-19 69.2 0.4 3.3 3 0 0 3 3 3 3 Helicase associated domain PsaN PF05479.11 OEU07320.1 - 0.098 12.8 0.6 28 4.9 0.0 3.0 3 0 0 3 3 3 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Phage_lysozyme2 PF18013.1 OEU07320.1 - 0.2 11.7 5.7 0.32 11.0 4.8 2.0 1 1 0 1 1 1 0 Phage tail lysozyme YvbH_ext PF11724.8 OEU07320.1 - 0.39 11.1 5.6 27 5.2 0.0 4.2 5 0 0 5 5 5 0 YvbH-like oligomerisation region PMR5N PF14416.6 OEU07320.1 - 1.2 9.5 5.8 22 5.5 0.1 3.7 3 0 0 3 3 3 0 PMR5 N terminal Domain MADF_DNA_bdg PF10545.9 OEU07320.1 - 8.8 6.7 11.3 13 6.2 1.3 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_hydro_cc PF11790.8 OEU07321.1 - 4.8e-05 23.0 0.0 8.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PT PF04886.12 OEU07321.1 - 0.0063 16.0 20.5 0.1 12.1 20.5 2.5 1 1 0 1 1 1 1 PT repeat Peptidase_S49_N PF08496.10 OEU07323.1 - 6.2 6.9 9.0 15 5.6 0.8 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_M50 PF02163.22 OEU07325.1 - 8.3e-05 22.0 7.7 0.031 13.6 1.5 3.4 1 1 1 2 2 2 2 Peptidase family M50 Peptidase_U32_C PF16325.5 OEU07327.1 - 0.19 12.0 0.0 9.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain WSC PF01822.19 OEU07327.1 - 5.5 7.3 16.3 0.25 11.5 8.8 2.8 3 0 0 3 3 3 0 WSC domain MFS_1 PF07690.16 OEU07328.1 - 4.2e-28 98.3 32.1 4.2e-28 98.3 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU07328.1 - 8.4e-07 28.2 37.9 7.1e-05 21.8 37.2 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter FKBP_C PF00254.28 OEU07330.1 - 2.7e-18 66.0 0.0 3.3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Tho2 PF11262.8 OEU07331.1 - 4.7e-65 219.8 2.3 3.4e-64 216.9 0.0 2.4 1 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 OEU07331.1 - 3.8e-35 121.7 7.2 1.6e-18 66.7 0.5 4.0 5 0 0 5 5 5 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 OEU07331.1 - 1.2e-27 95.8 0.0 3.7e-27 94.2 0.0 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit ADP_ribosyl_GH PF03747.14 OEU07331.1 - 0.065 13.0 0.5 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Spectrin PF00435.21 OEU07331.1 - 2.4 8.7 8.5 0.23 12.0 0.7 2.7 2 0 0 2 2 2 0 Spectrin repeat PALP PF00291.25 OEU07332.1 - 3.4e-43 148.2 0.0 4.5e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme C2 PF00168.30 OEU07333.1 - 7.1e-29 100.1 0.0 7.7e-13 48.6 0.0 2.9 2 1 1 3 3 3 2 C2 domain DUF4637 PF15470.6 OEU07334.1 - 0.021 14.6 0.6 0.034 13.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ureide_permease PF07168.11 OEU07334.1 - 0.28 9.9 0.3 0.38 9.5 0.3 1.1 1 0 0 1 1 1 0 Ureide permease EVI2A PF05399.11 OEU07334.1 - 0.62 9.6 8.3 0.98 9.0 8.3 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) GREB1 PF15782.5 OEU07334.1 - 0.79 6.8 5.0 0.92 6.5 5.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Secretin_N_2 PF07655.13 OEU07334.1 - 2.1 9.0 17.2 12 6.5 0.1 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CDC45 PF02724.14 OEU07334.1 - 7.5 4.7 11.8 9.5 4.4 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Rad52_Rad22 PF04098.15 OEU07335.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein LicD PF04991.13 OEU07337.1 - 4.9e-16 59.6 1.4 2.3e-12 47.6 1.2 2.9 1 1 1 2 2 2 2 LicD family NAD_binding_1 PF00175.21 OEU07339.1 - 2.1e-23 83.0 0.0 3.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU07339.1 - 9.5e-14 51.6 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OEU07339.1 - 0.12 12.5 0.0 3.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Ferric reductase NAD binding domain EGF_2 PF07974.13 OEU07341.1 - 1e-11 44.9 105.8 0.00036 20.8 0.0 10.9 9 2 0 9 9 9 7 EGF-like domain EGF PF00008.27 OEU07341.1 - 8.2e-07 29.2 105.4 0.0097 16.2 0.5 11.8 11 0 0 11 11 11 11 EGF-like domain Mito_carr PF00153.27 OEU07342.1 - 1.3e-58 195.0 4.4 4e-20 71.5 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5038 PF16441.5 OEU07345.1 - 0.59 10.1 3.5 0.37 10.8 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5038) Nsp1_C PF05064.13 OEU07346.1 - 0.079 12.8 12.7 0.72 9.7 0.9 3.5 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF3947 PF13135.6 OEU07346.1 - 0.19 12.0 0.8 0.43 10.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) SpecificRecomb PF10136.9 OEU07346.1 - 2.6 6.2 5.4 4 5.6 5.4 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF262 PF03235.14 OEU07346.1 - 4.1 7.5 16.1 2.8 8.1 9.0 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF262 GIDA PF01134.22 OEU07347.1 - 0.085 11.9 2.4 0.1 11.7 2.4 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.25 OEU07348.1 - 3.8e-69 233.0 0.0 4.6e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU07348.1 - 1.7e-28 99.6 0.0 2.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OEU07348.1 - 9.3e-06 24.8 0.2 1.4e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OEU07348.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OEU07348.1 - 0.0086 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OEU07348.1 - 0.045 12.8 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OEU07348.1 - 0.051 12.9 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU07348.1 - 0.064 12.0 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase EamA PF00892.20 OEU07349.1 - 1.8e-12 47.6 23.6 1.3e-06 28.6 8.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OEU07349.1 - 0.0002 20.7 1.0 0.0002 20.7 1.0 2.2 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport PT PF04886.12 OEU07352.1 - 2.8e-28 97.2 437.8 0.0023 17.5 26.0 20.6 5 3 7 12 12 12 5 PT repeat Cupin_8 PF13621.6 OEU07353.1 - 0.0041 16.9 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Androgen_recep PF02166.16 OEU07353.1 - 3.4 6.4 9.6 0.22 10.3 0.1 2.2 2 0 0 2 2 2 0 Androgen receptor Thioredoxin PF00085.20 OEU07354.1 - 1.4e-12 47.5 0.3 2.4e-12 46.8 0.3 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU07354.1 - 8.5e-05 22.8 0.1 0.00023 21.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU07354.1 - 0.0013 18.6 0.1 0.0065 16.4 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family EutK_C PF16365.5 OEU07355.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Fasciclin PF02469.22 OEU07357.1 - 8.3e-36 123.0 0.0 9.6e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain DUF4342 PF14242.6 OEU07357.1 - 0.028 14.4 4.5 0.36 10.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Nucleotid_trans PF03407.16 OEU07358.1 - 1.4e-11 44.8 0.1 3.5e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF2207 PF09972.9 OEU07359.1 - 0.21 10.3 0.0 0.25 10.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 OEU07359.1 - 0.38 10.2 1.9 0.76 9.2 1.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SBBP PF06739.11 OEU07360.1 - 0.0059 16.6 0.2 0.0059 16.6 0.2 4.2 4 0 0 4 4 4 1 Beta-propeller repeat Kelch_6 PF13964.6 OEU07360.1 - 3.3 8.2 8.0 39 4.7 0.0 4.8 5 0 0 5 5 5 0 Kelch motif SBBP PF06739.11 OEU07361.1 - 0.0019 18.2 3.0 0.0019 18.2 3.0 9.6 10 0 0 10 10 10 4 Beta-propeller repeat Ala_racemase_C PF00842.21 OEU07361.1 - 0.054 13.3 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain EF-hand_1 PF00036.32 OEU07363.1 - 6.4e-18 62.9 6.1 4.3e-06 25.9 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 OEU07363.1 - 3.1e-17 61.2 5.6 1.2e-06 27.7 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OEU07363.1 - 4.8e-16 57.3 1.4 1.6e-05 24.4 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 OEU07363.1 - 8e-14 51.8 4.2 4.5e-10 39.8 1.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OEU07363.1 - 5.1e-07 29.4 5.4 0.0021 17.9 0.9 2.8 2 1 1 3 3 3 3 EF-hand domain pair Dockerin_1 PF00404.18 OEU07363.1 - 4.5e-05 23.6 2.2 0.067 13.4 0.9 2.9 2 1 1 3 3 3 3 Dockerin type I domain EF-hand_13 PF17958.1 OEU07363.1 - 0.0013 18.5 0.0 0.18 11.7 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU07363.1 - 0.0019 18.5 0.6 0.1 13.0 0.3 2.6 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Soc PF16855.5 OEU07363.1 - 0.046 14.2 0.0 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 Small outer capsid protein p25-alpha PF05517.12 OEU07363.1 - 0.07 13.3 0.4 0.36 11.0 0.4 1.9 1 1 0 1 1 1 0 p25-alpha Terminase_GpA PF05876.12 OEU07363.1 - 0.093 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) EF-hand_4 PF12763.7 OEU07363.1 - 0.13 12.3 2.1 9 6.3 0.1 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand PMBR PF09373.10 OEU07363.1 - 0.19 12.0 0.1 1.7 8.9 0.0 2.4 3 0 0 3 3 3 0 Pseudomurein-binding repeat Abhydrolase_1 PF00561.20 OEU07364.1 - 3.7e-06 26.8 0.0 9.8e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU07364.1 - 8.7e-05 21.9 0.3 0.00033 20.0 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU07364.1 - 0.015 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 OEU07364.1 - 0.02 14.3 0.1 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 OEU07364.1 - 0.067 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OEU07364.1 - 0.093 12.5 0.1 0.55 10.0 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family RuvB_C PF05491.13 OEU07365.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Rif1_N PF12231.8 OEU07365.1 - 0.12 11.3 0.0 0.66 8.9 0.0 2.0 2 1 0 2 2 2 0 Rap1-interacting factor 1 N terminal Pkinase PF00069.25 OEU07367.1 - 8.3e-23 81.1 0.0 1.3e-22 80.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU07367.1 - 8.9e-11 41.5 0.0 1.7e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 OEU07367.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PDZ_6 PF17820.1 OEU07368.1 - 1.8e-06 27.7 0.1 0.00094 19.0 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PGPGW PF09656.10 OEU07368.1 - 2.6e-05 23.6 1.1 5.2e-05 22.7 1.1 1.5 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) PDZ PF00595.24 OEU07368.1 - 7e-05 23.1 0.8 0.38 11.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OEU07368.1 - 0.1 12.9 0.3 0.69 10.3 0.1 2.2 2 0 0 2 2 2 0 PDZ domain Macoilin PF09726.9 OEU07368.1 - 0.51 8.8 17.9 0.051 12.1 4.4 2.1 2 0 0 2 2 2 0 Macoilin family FAM176 PF14851.6 OEU07368.1 - 0.59 9.8 3.9 0.75 9.5 0.1 2.8 3 0 0 3 3 3 0 FAM176 family DUF1635 PF07795.11 OEU07368.1 - 1.8 8.4 11.0 0.11 12.4 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Lin-8 PF03353.15 OEU07368.1 - 3.5 7.1 11.6 0.067 12.8 1.2 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF775 PF05603.12 OEU07368.1 - 5.9 6.4 8.7 1 8.9 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF775) ABC_tran PF00005.27 OEU07369.1 - 1.2e-44 152.2 0.3 1.3e-22 80.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OEU07369.1 - 1.5e-16 61.1 6.6 1.5e-06 28.2 0.1 4.4 4 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OEU07369.1 - 5.2e-13 48.8 4.6 5.2e-13 48.8 4.6 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 OEU07369.1 - 1.1e-12 47.8 0.0 0.00021 20.8 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OEU07369.1 - 1.9e-05 24.3 0.1 0.062 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OEU07369.1 - 3.7e-05 23.8 0.0 0.42 10.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 OEU07369.1 - 0.00029 20.8 0.3 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 OEU07369.1 - 0.00035 20.4 8.4 0.27 10.9 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 OEU07369.1 - 0.0013 19.3 14.7 0.5 10.8 0.0 3.8 3 1 1 4 4 4 2 AAA domain SbcCD_C PF13558.6 OEU07369.1 - 0.0014 18.9 0.1 0.09 13.0 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 OEU07369.1 - 0.0016 18.2 0.7 0.48 10.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OEU07369.1 - 0.0017 18.1 0.1 0.28 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OEU07369.1 - 0.0021 18.3 1.3 1.8 8.9 0.0 3.3 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 OEU07369.1 - 0.0029 17.5 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 OEU07369.1 - 0.003 17.8 0.6 0.83 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OEU07369.1 - 0.0038 17.6 0.4 2.6 8.4 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OEU07369.1 - 0.0046 17.4 0.0 5 7.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU07369.1 - 0.0048 16.5 0.0 1.7 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OEU07369.1 - 0.006 16.7 0.5 0.34 11.0 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 OEU07369.1 - 0.0079 16.6 0.2 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OEU07369.1 - 0.01 15.1 1.8 3.2 6.9 0.0 3.3 3 1 0 3 3 3 1 NB-ARC domain AAA_5 PF07728.14 OEU07369.1 - 0.047 13.7 0.3 11 6.1 0.2 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OEU07369.1 - 0.051 12.7 1.3 4.2 6.4 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 OEU07369.1 - 0.069 12.7 0.3 29 4.2 0.1 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_14 PF13173.6 OEU07369.1 - 0.07 13.2 0.1 27 4.8 0.0 3.4 4 0 0 4 4 2 0 AAA domain TsaE PF02367.17 OEU07369.1 - 0.073 13.1 0.2 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 OEU07369.1 - 0.082 13.0 1.6 0.71 9.9 0.0 2.8 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 OEU07369.1 - 0.1 12.8 0.1 26 5.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 OEU07369.1 - 0.11 12.4 0.2 21 5.0 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain PepSY_TM_like_2 PF16357.5 OEU07369.1 - 0.12 12.4 0.4 0.25 11.3 0.4 1.5 1 0 0 1 1 1 0 Putative PepSY_TM-like AAA_7 PF12775.7 OEU07369.1 - 0.13 11.7 0.1 13 5.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 OEU07369.1 - 0.17 12.1 0.7 18 5.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 OEU07369.1 - 0.19 11.3 0.1 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 OEU07369.1 - 0.24 10.4 1.8 16 4.3 0.0 3.1 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OEU07369.1 - 0.59 10.7 6.3 0.79 10.3 0.0 3.1 4 0 0 4 4 2 0 AAA domain Pkinase PF00069.25 OEU07371.1 - 3.5e-28 98.7 1.3 8.6e-21 74.5 0.2 4.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU07371.1 - 4.8e-14 52.3 0.1 3.7e-12 46.1 0.0 3.5 2 2 0 2 2 2 1 Protein tyrosine kinase Whirly PF08536.11 OEU07372.1 - 1.5e-08 34.6 0.0 3.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Whirly transcription factor YqjK PF13997.6 OEU07372.1 - 1.1 9.6 4.3 32 4.9 2.7 2.3 2 0 0 2 2 2 0 YqjK-like protein SOUL PF04832.12 OEU07375.1 - 9.5e-22 77.9 0.0 1.7e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein DNA_pol_A_exo1 PF01612.20 OEU07377.1 - 1.8e-17 63.6 2.1 4.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 3'-5' exonuclease Ank_2 PF12796.7 OEU07377.1 - 1.9e-07 31.6 0.0 8.4e-07 29.5 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU07377.1 - 0.00013 22.4 0.1 0.2 12.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU07377.1 - 0.0014 18.9 0.0 0.096 13.0 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) tRNA_edit PF04073.15 OEU07377.1 - 0.0037 17.3 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Ank_3 PF13606.6 OEU07377.1 - 0.13 12.9 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat PT PF04886.12 OEU07378.1 - 1.7e-07 30.6 13.5 0.0065 16.0 13.5 2.2 1 1 0 1 1 1 1 PT repeat Mucin PF01456.17 OEU07379.1 - 10 6.1 24.3 0.43 10.6 9.4 3.3 4 0 0 4 4 4 0 Mucin-like glycoprotein DUF913 PF06025.12 OEU07380.1 - 0.032 13.2 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4116 PF13475.6 OEU07381.1 - 1.7e-29 101.3 4.2 8.5e-08 31.8 0.0 9.6 8 2 4 12 12 12 7 Domain of unknown function (DUF4116) Myc_N PF01056.18 OEU07381.1 - 0.042 13.7 7.0 0.078 12.9 7.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 OEU07381.1 - 0.069 11.3 11.7 0.12 10.5 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OEU07381.1 - 0.1 10.8 9.3 0.18 10.0 9.3 1.3 1 0 0 1 1 1 0 Nop14-like family AAA_11 PF13086.6 OEU07381.1 - 0.19 11.5 1.7 0.37 10.5 1.7 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 OEU07381.1 - 0.61 10.3 14.4 6 7.1 11.9 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.16 OEU07381.1 - 0.62 9.2 6.4 1.3 8.2 6.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PI3K_1B_p101 PF10486.9 OEU07381.1 - 0.68 7.6 5.3 1 7.0 5.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 OEU07381.1 - 1.7 6.9 6.8 3.2 5.9 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 OEU07381.1 - 2.2 8.3 9.5 2 8.4 6.9 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 OEU07381.1 - 4.2 7.0 10.6 3.3 7.4 8.3 1.9 2 0 0 2 2 2 0 FAM176 family DUF4637 PF15470.6 OEU07381.1 - 7.1 6.3 11.3 16 5.2 11.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SET PF00856.28 OEU07382.1 - 1.9e-06 28.4 0.0 4.2e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 SET domain RE_MjaI PF09568.10 OEU07382.1 - 0.081 12.7 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 MjaI restriction endonuclease zf-MYND PF01753.18 OEU07383.1 - 2.4e-07 30.7 15.7 5.5e-07 29.6 15.7 1.7 1 0 0 1 1 1 1 MYND finger PMP22_Claudin PF00822.20 OEU07384.1 - 0.0019 18.1 2.0 0.0019 18.1 2.0 1.5 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family RskA PF10099.9 OEU07385.1 - 0.025 14.9 0.0 0.034 14.4 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2771 PF10969.8 OEU07385.1 - 0.062 13.3 0.7 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) Ank_2 PF12796.7 OEU07386.1 - 0.00037 21.0 0.0 0.076 13.6 0.0 2.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OEU07386.1 - 0.033 14.6 0.0 44 4.8 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeat Spt4 PF06093.13 OEU07388.1 - 6.7e-26 90.2 0.0 8.7e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-tcix PF14952.6 OEU07388.1 - 0.054 13.1 2.5 0.26 10.9 1.4 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding RecR PF02132.15 OEU07388.1 - 0.21 11.2 1.7 0.47 10.1 1.8 1.6 1 1 0 1 1 1 0 RecR protein DUF563 PF04577.14 OEU07389.1 - 0.0002 21.6 0.1 0.00046 20.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3788 PF12663.7 OEU07390.1 - 0.045 13.7 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) DUF1275 PF06912.11 OEU07391.1 - 5.6e-14 52.5 7.1 6.8e-14 52.2 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) YbgT_YccB PF08173.11 OEU07391.1 - 0.18 12.0 2.9 0.19 11.8 0.5 2.2 2 0 0 2 2 2 0 Membrane bound YbgT-like protein HKR_ArcB_TM PF18415.1 OEU07391.1 - 0.49 11.2 2.5 7.5 7.4 0.0 3.1 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Clr2_transil PF16761.5 OEU07392.1 - 0.034 15.0 0.1 0.2 12.5 0.1 2.2 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 Sporozoite_P67 PF05642.11 OEU07392.1 - 0.19 9.8 5.7 0.24 9.4 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 OEU07392.1 - 0.62 8.3 12.2 0.77 8.0 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 OEU07392.1 - 1.8 8.3 11.4 3.4 7.4 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 OEU07392.1 - 1.9 6.5 13.1 2.8 5.9 13.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_1 PF00583.25 OEU07393.1 - 2.2e-07 31.1 0.4 1.4e-05 25.3 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OEU07393.1 - 0.00013 22.0 0.1 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU07393.1 - 0.0014 19.0 0.2 0.0032 17.9 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OEU07393.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase SR-25 PF10500.9 OEU07393.1 - 0.013 15.1 11.3 0.013 15.1 11.3 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Acetyltransf_10 PF13673.7 OEU07393.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU07393.1 - 0.13 12.2 0.0 21 5.1 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein DUF2206 PF09971.9 OEU07393.1 - 0.38 9.5 3.1 0.69 8.6 3.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) F-box-like PF12937.7 OEU07394.1 - 3.7e-06 26.7 0.2 1.9e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OEU07394.1 - 0.00017 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OEU07394.1 - 0.0018 18.1 0.2 0.0087 15.9 0.0 2.2 2 0 0 2 2 2 1 F-box Ogr_Delta PF04606.12 OEU07394.1 - 0.024 14.6 0.2 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger PRANC PF09372.10 OEU07394.1 - 0.046 14.1 3.4 0.055 13.8 0.2 2.7 3 0 0 3 3 3 0 PRANC domain Nudix_N_2 PF14803.6 OEU07395.1 - 0.62 10.0 3.3 1.2 9.1 3.3 1.5 1 0 0 1 1 1 0 Nudix N-terminal C1_1 PF00130.22 OEU07395.1 - 0.81 9.6 4.0 1.8 8.5 4.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF454 PF04304.13 OEU07395.1 - 1 9.4 4.3 3.5 7.7 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF697 PF05128.12 OEU07395.1 - 1.8 8.3 6.0 3.3 7.4 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Tudor_FRX1 PF18336.1 OEU07396.1 - 0.029 14.3 0.4 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain MtN3_slv PF03083.16 OEU07398.1 - 7.7e-24 83.6 9.3 6.1e-18 64.6 3.5 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF4064 PF13273.6 OEU07398.1 - 0.79 10.0 5.2 17 5.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) ETC_C1_NDUFA4 PF04800.12 OEU07400.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 ETC complex I subunit conserved region LisH PF08513.11 OEU07400.1 - 0.065 13.2 0.7 0.15 12.1 0.7 1.6 1 0 0 1 1 1 0 LisH Ntox35 PF15534.6 OEU07400.1 - 0.095 13.2 0.0 0.23 11.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial toxin 35 zf-CXXC PF02008.20 OEU07401.1 - 1.4e-12 47.5 37.4 1.1e-10 41.3 17.4 4.9 5 0 0 5 5 5 2 CXXC zinc finger domain PHD PF00628.29 OEU07401.1 - 2.1e-10 40.3 38.0 6.1e-10 38.9 14.0 4.5 4 1 1 5 5 5 2 PHD-finger Arm PF00514.23 OEU07401.1 - 0.0003 20.7 7.3 0.28 11.3 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OEU07401.1 - 0.0011 19.3 0.5 4.8 7.7 0.1 3.5 2 1 0 3 3 3 1 HEAT repeats Atx10homo_assoc PF09759.9 OEU07401.1 - 0.0061 16.6 4.2 0.072 13.1 0.1 3.6 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain AT_hook PF02178.19 OEU07401.1 - 0.44 10.6 5.2 1.5 9.0 5.2 1.9 1 0 0 1 1 1 0 AT hook motif zf-RING_2 PF13639.6 OEU07402.1 - 0.0004 20.7 10.7 0.14 12.5 1.8 3.2 3 0 0 3 3 3 3 Ring finger domain zf-C3HC4_3 PF13920.6 OEU07402.1 - 0.00065 19.5 11.0 0.2 11.5 2.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU07402.1 - 0.0013 18.7 12.4 0.01 15.9 8.5 3.2 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OEU07402.1 - 0.013 15.3 13.3 7.3 6.5 0.1 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 CEBP_ZZ PF16366.5 OEU07402.1 - 0.021 15.1 2.3 0.021 15.1 2.3 1.6 2 0 0 2 2 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4 PF00097.25 OEU07402.1 - 0.021 14.7 11.7 0.035 14.0 7.8 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cys_rich_CPCC PF14206.6 OEU07402.1 - 0.051 13.4 1.0 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-C3HC4_5 PF17121.5 OEU07402.1 - 0.26 11.2 8.4 12 5.8 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU07402.1 - 0.34 10.8 12.5 0.59 10.0 2.9 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU07402.1 - 0.69 9.9 16.9 27 4.8 17.0 2.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-MIZ PF02891.20 OEU07402.1 - 2.1 8.2 8.1 5.5 6.8 1.6 3.1 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger FYVE PF01363.21 OEU07402.1 - 5.1 7.3 11.1 1.3e+02 2.8 11.0 2.6 1 1 0 1 1 1 0 FYVE zinc finger Ndc1_Nup PF09531.10 OEU07403.1 - 3.7 6.1 9.5 5.3 5.6 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAT1 PF06391.13 OEU07404.1 - 1.8 8.3 21.2 6.4 6.5 15.7 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 MFS_1 PF07690.16 OEU07405.1 - 7.1e-47 160.0 27.9 3.3e-42 144.7 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU07405.1 - 2.1e-11 43.4 14.4 4.2e-11 42.4 0.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Yae1_N PF09811.9 OEU07408.1 - 1.1e-08 34.6 55.9 0.17 11.6 0.2 12.0 6 2 2 8 8 8 6 Essential protein Yae1, N terminal Cellsynth_D PF03500.13 OEU07408.1 - 0.039 13.8 0.0 3.1 7.7 0.0 3.4 3 2 1 4 4 4 0 Cellulose synthase subunit D PAE PF03283.13 OEU07413.1 - 5.9e-19 68.4 0.3 2.5e-18 66.4 0.0 2.1 2 1 0 2 2 2 1 Pectinacetylesterase ABC_tran PF00005.27 OEU07413.1 - 1.3e-17 64.6 0.0 3.6e-17 63.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU07413.1 - 2.9e-10 40.4 0.7 0.0003 20.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 OEU07413.1 - 2.1e-06 27.3 13.6 2.1e-06 27.3 13.6 2.2 2 0 0 2 2 2 1 ABC-2 type transporter AAA_15 PF13175.6 OEU07413.1 - 6e-05 22.9 2.2 0.004 16.9 2.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OEU07413.1 - 0.00083 19.1 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU07413.1 - 0.0049 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OEU07413.1 - 0.007 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OEU07413.1 - 0.0071 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 OEU07413.1 - 0.028 13.6 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MscS_TM PF12794.7 OEU07413.1 - 0.073 11.9 0.8 0.15 10.9 0.8 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ATG22 PF11700.8 OEU07414.1 - 2.4e-13 49.5 12.5 1.1e-11 44.1 12.5 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OEU07414.1 - 0.0014 17.7 14.4 0.0029 16.6 14.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Holin_SPP1 PF04688.13 OEU07414.1 - 1.9 8.7 6.3 10 6.4 2.2 2.6 2 0 0 2 2 2 0 SPP1 phage holin Chloroa_b-bind PF00504.21 OEU07415.1 - 1.7e-28 100.2 0.5 2.2e-28 99.8 0.4 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Polyketide_cyc PF03364.20 OEU07417.1 - 1.2e-05 25.5 0.0 0.0003 21.0 0.0 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 OEU07417.1 - 0.072 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) CCDC53 PF10152.9 OEU07417.1 - 0.086 13.3 2.7 0.16 12.4 2.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GST_N_3 PF13417.6 OEU07418.1 - 1.2e-14 54.4 0.1 3e-14 53.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU07418.1 - 1.6e-11 44.3 0.0 3.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU07418.1 - 3.8e-07 30.4 0.0 7.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU07418.1 - 0.0017 18.3 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OEU07418.1 - 0.01 16.6 0.2 0.039 14.7 0.2 2.0 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glyco_hydro_97 PF10566.9 OEU07419.1 - 0.063 12.5 0.1 0.084 12.1 0.1 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 CI-B14_5a PF07347.12 OEU07420.1 - 0.019 14.8 1.7 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Presenilin PF01080.17 OEU07420.1 - 4.6 5.9 4.4 6.7 5.4 4.4 1.3 1 0 0 1 1 1 0 Presenilin DUF4530 PF15039.6 OEU07420.1 - 4.9 7.3 6.9 0.49 10.5 0.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4530) TMEM51 PF15345.6 OEU07421.1 - 0.00086 19.2 0.9 0.00086 19.2 0.9 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 Herpes_gE PF02480.16 OEU07421.1 - 0.0024 16.7 0.1 0.0038 16.0 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2207 PF09972.9 OEU07421.1 - 0.0026 16.6 0.1 0.0048 15.7 0.0 1.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 OEU07421.1 - 0.0032 17.4 0.5 0.0032 17.4 0.5 2.3 1 1 1 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OEU07421.1 - 0.0033 18.3 0.4 0.013 16.3 0.0 2.3 1 1 1 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Gypsy PF07253.11 OEU07421.1 - 0.018 13.6 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein FAM176 PF14851.6 OEU07421.1 - 0.033 13.9 0.0 0.033 13.9 0.0 2.0 2 1 1 3 3 3 0 FAM176 family Nitrate_red_gam PF02665.14 OEU07421.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4381 PF14316.6 OEU07421.1 - 0.14 12.3 0.1 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Gram_pos_anchor PF00746.21 OEU07421.1 - 0.15 12.0 1.2 0.41 10.6 1.2 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF1180 PF06679.12 OEU07421.1 - 0.53 10.7 3.9 0.27 11.6 1.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Goodbye PF17109.5 OEU07421.1 - 1.5 9.3 3.1 16 6.0 0.0 3.0 2 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain SVIP PF15811.5 OEU07423.1 - 0.013 16.0 1.4 0.013 16.0 1.4 2.7 3 0 0 3 3 3 0 Small VCP/p97-interacting protein Myb_DNA-binding PF00249.31 OEU07423.1 - 0.043 14.0 0.3 0.043 14.0 0.3 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain HA PF03457.14 OEU07424.1 - 4.9e-53 177.3 7.4 3.6e-17 62.4 0.4 3.0 3 0 0 3 3 3 3 Helicase associated domain Antirestrict PF03230.13 OEU07424.1 - 0.012 15.6 0.2 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Antirestriction protein TSGP1 PF07771.11 OEU07424.1 - 0.026 14.7 0.2 0.054 13.6 0.2 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Ank_4 PF13637.6 OEU07425.1 - 0.026 15.1 0.0 4.2 8.1 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU07425.1 - 0.076 13.4 0.0 25 5.3 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) HA PF03457.14 OEU07426.1 - 3.3e-17 62.6 2.2 1.4e-14 54.2 0.3 3.0 3 0 0 3 3 3 2 Helicase associated domain FKBP_C PF00254.28 OEU07427.1 - 1.5e-06 28.4 0.0 0.00027 21.2 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase HSF_DNA-bind PF00447.17 OEU07428.1 - 1.1e-11 45.2 0.0 3.1e-06 27.7 0.0 2.5 1 1 1 2 2 2 2 HSF-type DNA-binding CFIA_Pcf11 PF11526.8 OEU07428.1 - 0.085 13.4 6.7 0.29 11.7 0.3 2.4 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 MctB PF11382.8 OEU07429.1 - 0.0027 17.5 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB DUF4328 PF14219.6 OEU07429.1 - 0.23 11.0 0.1 0.57 9.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) ABC2_membrane_3 PF12698.7 OEU07429.1 - 6.8 5.7 9.0 0.063 12.4 0.2 2.1 3 0 0 3 3 3 0 ABC-2 family transporter protein Cu_bind_like PF02298.17 OEU07430.1 - 0.043 13.8 0.5 0.1 12.6 0.5 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Cupin_2 PF07883.11 OEU07430.1 - 0.054 13.2 0.6 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Cupin domain RAP1 PF07218.11 OEU07430.1 - 0.27 9.5 3.1 0.37 9.0 3.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Flavodoxin_1 PF00258.25 OEU07432.1 - 1.5e-20 73.8 1.2 1.7e-20 73.7 1.2 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OEU07432.1 - 5.5e-06 26.2 0.1 2.2e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 OEU07432.1 - 0.0019 18.5 0.1 0.003 17.8 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin domain BetR PF08667.10 OEU07432.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 BetR domain LRR_4 PF12799.7 OEU07433.1 - 0.00054 20.3 25.9 0.023 15.1 1.4 5.8 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU07433.1 - 0.035 13.9 12.9 0.69 9.7 4.6 4.5 3 1 0 3 3 3 0 Leucine rich repeat ApeA_NTD1 PF18862.1 OEU07433.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ApeA N-terminal domain 1 LRR_9 PF14580.6 OEU07433.1 - 0.14 11.6 7.6 1.3 8.5 0.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeat Cu_bind_like PF02298.17 OEU07436.1 - 0.15 12.1 0.3 0.45 10.6 0.1 2.0 2 1 0 2 2 2 0 Plastocyanin-like domain Lipase_3 PF01764.25 OEU07440.1 - 8.5e-17 61.3 0.0 4.8e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Ribosomal_L11_N PF03946.14 OEU07440.1 - 0.013 15.3 0.4 0.039 13.8 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Mitofilin PF09731.9 OEU07440.1 - 0.044 12.6 4.6 0.083 11.7 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Syntaxin_2 PF14523.6 OEU07440.1 - 0.064 13.6 5.5 0.057 13.8 1.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF883 PF05957.13 OEU07440.1 - 0.12 13.0 0.1 0.25 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Cdh1_DBD_1 PF18196.1 OEU07440.1 - 2.1 8.7 7.5 7.5 6.9 3.6 2.3 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 KMP11 PF03037.16 OEU07440.1 - 5.4 7.9 8.0 0.7 10.7 0.6 3.2 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 Mis14 PF08641.12 OEU07441.1 - 0.0012 19.2 2.4 1 9.7 0.7 2.7 1 1 1 2 2 2 2 Kinetochore protein Mis14 like FliL PF03748.14 OEU07441.1 - 0.28 11.8 2.8 1 10.0 1.3 2.3 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL BTB PF00651.31 OEU07442.1 - 2.9e-12 46.8 1.3 2e-11 44.1 0.2 2.2 1 1 1 2 2 2 1 BTB/POZ domain SAP PF02037.27 OEU07442.1 - 0.0078 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain BACK PF07707.15 OEU07442.1 - 0.21 11.7 1.6 1.2 9.2 0.1 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch HA PF03457.14 OEU07444.1 - 1.9e-55 185.0 8.4 9.9e-19 67.4 0.1 3.1 3 0 0 3 3 3 3 Helicase associated domain DUF4936 PF16290.5 OEU07444.1 - 0.004 17.8 0.9 0.59 10.9 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4936) DUF4064 PF13273.6 OEU07445.1 - 0.0044 17.3 5.7 1.2 9.4 0.0 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF4064) CENP-B_dimeris PF09026.10 OEU07445.1 - 1.2 9.5 10.1 5.2 7.5 0.6 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Phage_holin_2_2 PF10746.9 OEU07445.1 - 4.1 7.1 6.0 1.8 8.3 0.3 2.4 1 1 1 2 2 2 0 Phage holin T7 family, holin superfamily II Iron_traffic PF04362.14 OEU07446.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Ycf34 PF10718.9 OEU07447.1 - 4e-23 81.9 14.4 9.7e-20 71.0 2.3 2.7 3 0 0 3 3 3 2 Hypothetical chloroplast protein Ycf34 RNase_H2_suC PF08615.11 OEU07447.1 - 0.087 13.0 2.4 0.13 12.4 2.4 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Sporozoite_P67 PF05642.11 OEU07447.1 - 1.7 6.6 10.0 2.1 6.3 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GP67 PF17634.2 OEU07447.1 - 3.4 8.2 14.1 7.9 7.0 14.1 1.6 1 0 0 1 1 1 0 Gene product 67 DUF4611 PF15387.6 OEU07447.1 - 6.9 7.0 12.4 7 6.9 11.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Chitin_synth_1 PF01644.17 OEU07448.1 - 1e-07 32.1 0.0 3.6e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OEU07448.1 - 8.9e-05 21.3 0.6 1.5 7.3 0.5 3.7 4 0 0 4 4 4 3 Chitin synthase Glycos_transf_2 PF00535.26 OEU07448.1 - 0.0003 20.6 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OEU07448.1 - 0.12 12.3 0.0 4.7 7.0 0.0 2.5 3 0 0 3 3 3 0 Glycosyltransferase like family 2 YjfB_motility PF14070.6 OEU07448.1 - 0.27 11.4 5.3 0.57 10.4 5.3 1.4 1 0 0 1 1 1 0 Putative motility protein Glyco_trans_2_3 PF13632.6 OEU07448.1 - 9.4 6.1 9.4 0.11 12.4 0.3 2.3 2 0 0 2 2 2 0 Glycosyl transferase family group 2 AMP-binding PF00501.28 OEU07449.1 - 2.4e-96 322.9 0.0 3.2e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sdh5 PF03937.16 OEU07450.1 - 2.9e-18 65.6 0.1 5.5e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Histone_H2A_C PF16211.5 OEU07452.1 - 1.7e-20 72.5 2.5 3.2e-20 71.6 2.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OEU07452.1 - 1.1e-14 54.9 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OEU07452.1 - 0.00031 21.0 0.0 0.00071 19.8 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ETRAMP PF09716.10 OEU07455.1 - 0.026 14.6 0.2 0.026 14.6 0.2 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pentapeptide_4 PF13599.6 OEU07455.1 - 0.24 11.6 4.0 14 5.9 0.0 4.8 3 2 1 4 4 4 0 Pentapeptide repeats (9 copies) DUF2981 PF11200.8 OEU07455.1 - 8.7 6.0 9.5 17 5.0 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ank_2 PF12796.7 OEU07456.1 - 7e-27 93.8 1.0 1.8e-14 54.1 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU07456.1 - 1.2e-18 67.2 0.7 5.2e-12 46.0 0.2 3.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU07456.1 - 1.7e-16 60.0 0.4 4e-05 23.8 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU07456.1 - 5e-16 57.2 0.4 0.00087 19.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OEU07456.1 - 2.8e-15 56.0 0.4 0.00023 21.5 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeat NAM-associated PF14303.6 OEU07456.1 - 0.078 13.7 0.1 0.16 12.7 0.1 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain FF PF01846.19 OEU07456.1 - 0.098 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 FF domain COX17 PF05051.13 OEU07457.1 - 2.2e-19 69.5 9.2 2.5e-19 69.3 9.2 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) PP2C PF00481.21 OEU07458.1 - 1.9e-35 122.8 0.1 3.6e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C RRN3 PF05327.11 OEU07459.1 - 0.92 8.0 5.6 1.2 7.6 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 OEU07459.1 - 1.2 8.4 11.7 1.6 7.9 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein EBV-NA3 PF05009.12 OEU07459.1 - 4.5 6.7 6.3 5.7 6.4 5.6 1.4 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) LRR_6 PF13516.6 OEU07460.1 - 1.1e-16 59.4 25.2 0.029 14.4 0.0 12.5 13 0 0 13 13 13 5 Leucine Rich repeat LRR_4 PF12799.7 OEU07460.1 - 1.3e-08 35.0 14.5 0.19 12.2 2.6 7.0 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU07460.1 - 1.7e-06 27.8 11.1 42 5.2 0.0 9.1 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.6 OEU07460.1 - 0.0013 18.5 18.5 0.88 9.4 2.9 6.7 3 3 1 4 4 4 2 Leucine rich repeat Helicase_C PF00271.31 OEU07461.1 - 1.7e-15 57.3 0.0 4.8e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU07461.1 - 6.3e-08 32.6 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 OEU07461.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) ABC_tran PF00005.27 OEU07461.1 - 0.11 13.0 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Spc7_N PF15402.6 OEU07461.1 - 0.14 10.4 8.2 0.21 9.8 8.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AAA_22 PF13401.6 OEU07461.1 - 0.43 10.9 1.5 4.4 7.6 1.5 2.6 1 1 0 1 1 1 0 AAA domain Dehydrin PF00257.19 OEU07462.1 - 6.3 7.3 6.2 0.61 10.6 0.7 1.9 2 0 0 2 2 2 0 Dehydrin Mcm10 PF09332.11 OEU07463.1 - 2.2 7.6 12.4 2.6 7.4 12.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor 7tm_1 PF00001.21 OEU07464.1 - 0.0059 16.0 1.6 1 8.6 0.0 3.3 3 1 1 4 4 4 1 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.9 OEU07464.1 - 0.012 14.5 0.3 4.2 6.0 0.5 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 OEU07464.1 - 0.14 11.9 5.6 0.21 11.3 0.1 3.2 3 1 0 4 4 4 0 Tetraspanin family DUF2933 PF11666.8 OEU07464.1 - 0.15 12.1 0.4 0.59 10.2 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) SLATT_1 PF18181.1 OEU07464.1 - 0.4 10.6 2.9 25 4.8 0.0 3.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Cadherin_C_2 PF16492.5 OEU07464.1 - 6.2 7.6 6.0 2.1 9.1 0.1 3.3 5 0 0 5 5 5 0 Cadherin cytoplasmic C-terminal Sulfotransfer_3 PF13469.6 OEU07465.1 - 0.0012 19.3 0.0 0.0054 17.1 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Fur_reg_FbpB PF13040.6 OEU07466.1 - 0.51 9.9 3.7 11 5.6 0.3 2.6 2 0 0 2 2 2 0 Fur-regulated basic protein B Glyco_tranf_2_4 PF13704.6 OEU07467.1 - 0.017 15.6 10.0 0.042 14.4 0.1 3.7 4 0 0 4 4 4 0 Glycosyl transferase family 2 AF-4 PF05110.13 OEU07467.1 - 0.14 10.3 69.0 0.0029 15.8 45.7 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Phospholip_A2_2 PF05826.12 OEU07468.1 - 0.1 12.8 0.0 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Phospholipase A2 Sulfotransfer_4 PF17784.1 OEU07468.1 - 0.14 12.0 0.0 1.2 8.9 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase domain ADH_zinc_N PF00107.26 OEU07470.1 - 1.5e-11 44.3 0.0 2.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU07470.1 - 0.0015 19.6 0.0 0.0019 19.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_8 PF13855.6 OEU07471.1 - 6.8e-10 38.6 28.6 7.6e-05 22.4 6.9 4.9 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OEU07471.1 - 3.1e-08 33.8 28.7 0.0023 18.3 4.4 5.0 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU07471.1 - 3.9e-05 23.6 23.3 0.33 11.6 0.7 7.1 6 3 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU07471.1 - 4.9 7.5 19.0 8 6.8 1.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Beta_helix_2 PF18835.1 OEU07473.1 - 0.017 14.8 0.4 0.045 13.5 0.4 1.7 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase FoP_duplication PF13865.6 OEU07473.1 - 7.7 7.1 14.7 20 5.8 14.7 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Band_7 PF01145.25 OEU07474.1 - 4.2e-35 121.4 0.8 7.9e-35 120.5 0.8 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OEU07474.1 - 0.082 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family DivIVA PF05103.13 OEU07474.1 - 0.17 12.0 6.3 0.32 11.1 6.3 1.5 1 0 0 1 1 1 0 DivIVA protein Flot PF15975.5 OEU07474.1 - 7.6 6.7 12.8 7.6 6.8 9.4 2.4 1 1 1 2 2 2 0 Flotillin Sacchrp_dh_C PF16653.5 OEU07479.1 - 9.3e-79 265.3 0.0 1.5e-78 264.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 OEU07479.1 - 1.9e-13 50.8 0.6 3.1e-12 46.9 0.6 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 OEU07479.1 - 5.7e-10 39.6 0.0 0.00062 20.1 0.0 3.6 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, N-terminal domain Saccharop_dh_N PF04455.12 OEU07479.1 - 1.6e-05 25.2 0.0 4.8e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 OEU07479.1 - 0.028 13.7 0.1 0.53 9.5 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAM60A PF15396.6 OEU07480.1 - 0.0098 15.9 0.6 0.0098 15.9 0.6 3.5 3 0 0 3 3 3 3 Protein Family FAM60A UCH PF00443.29 OEU07481.1 - 2.9e-45 154.8 0.1 1.6e-44 152.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU07481.1 - 3.8e-25 89.2 2.4 3.7e-19 69.5 0.6 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GOLD_2 PF13897.6 OEU07481.1 - 0.11 13.0 1.5 0.32 11.5 1.5 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Nuc_sug_transp PF04142.15 OEU07482.1 - 1.7e-55 188.4 11.0 2e-55 188.2 11.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OEU07482.1 - 4e-06 26.3 11.3 1.2e-05 24.7 11.1 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU07482.1 - 4.7e-05 23.6 28.3 0.00041 20.5 9.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU07482.1 - 0.005 16.2 3.6 0.005 16.2 3.6 1.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family DEAD PF00270.29 OEU07483.1 - 1.2e-48 165.2 0.0 1.9e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU07483.1 - 1e-31 109.6 0.0 1.8e-30 105.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU07483.1 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU07483.1 - 0.062 13.6 0.1 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 OEU07483.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF4386 PF14329.6 OEU07485.1 - 2.5e-26 92.9 21.5 3.2e-26 92.5 21.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) Vma12 PF11712.8 OEU07485.1 - 0.00026 21.1 0.1 0.00047 20.2 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Imm5 PF14423.6 OEU07486.1 - 3 8.0 12.6 0.16 12.2 6.3 2.1 2 1 1 3 3 3 0 Immunity protein Imm5 Aldedh PF00171.22 OEU07488.1 - 1.5e-105 353.4 0.0 2.8e-105 352.5 0.0 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF3079 PF11278.8 OEU07489.1 - 0.063 13.1 1.8 0.52 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) DUF3311 PF11755.8 OEU07490.1 - 0.011 15.6 2.9 0.026 14.5 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) DUF1279 PF06916.13 OEU07490.1 - 0.051 14.1 0.0 0.088 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DCP1 PF06058.13 OEU07491.1 - 3.7e-26 91.3 0.6 5.6e-26 90.8 0.6 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 OEU07491.1 - 0.003 16.8 1.6 0.0077 15.5 1.6 1.7 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus LPD1 PF18796.1 OEU07491.1 - 0.038 14.1 0.1 0.072 13.2 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 1 PknG_TPR PF16918.5 OEU07491.1 - 0.04 12.7 0.3 0.055 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat zf-MYND PF01753.18 OEU07492.1 - 1.4e-07 31.5 19.5 3.7e-07 30.1 19.5 1.8 1 1 0 1 1 1 1 MYND finger ETRAMP PF09716.10 OEU07492.1 - 3.6 7.7 12.9 0.23 11.5 1.3 2.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SpoU_methylase PF00588.19 OEU07493.1 - 3.1e-26 92.2 0.0 4.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Metallophos_2 PF12850.7 OEU07493.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BRAP2 PF07576.12 OEU07494.1 - 5.4e-07 29.8 0.3 1.2e-06 28.7 0.3 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 PBP1_TM PF14812.6 OEU07494.1 - 0.027 14.8 2.4 0.027 14.8 2.4 4.9 5 1 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RskA PF10099.9 OEU07494.1 - 0.066 13.5 2.4 0.38 11.0 0.0 2.9 3 2 0 3 3 3 0 Anti-sigma-K factor rskA Rsm1 PF08600.10 OEU07494.1 - 0.28 11.4 2.6 0.77 9.9 0.3 2.7 2 0 0 2 2 2 0 Rsm1-like LsmAD PF06741.13 OEU07494.1 - 0.3 11.7 0.0 0.3 11.7 0.0 4.0 5 0 0 5 5 5 0 LsmAD domain FHIPEP PF00771.20 OEU07495.1 - 0.27 9.7 3.1 0.44 9.0 3.1 1.3 1 0 0 1 1 1 0 FHIPEP family 2OG-FeII_Oxy_5 PF13759.6 OEU07495.1 - 0.53 10.7 0.0 0.53 10.7 0.0 3.4 4 1 0 4 4 4 0 Putative 2OG-Fe(II) oxygenase Androgen_recep PF02166.16 OEU07495.1 - 0.83 8.4 10.1 1.3 7.8 10.1 1.2 1 0 0 1 1 1 0 Androgen receptor Strabismus PF06638.11 OEU07496.1 - 0.17 10.5 0.0 0.17 10.5 0.0 2.3 3 0 0 3 3 3 0 Strabismus protein DUF4064 PF13273.6 OEU07496.1 - 1.6 9.1 11.3 16 5.9 8.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) YMF19 PF02326.15 OEU07496.1 - 5.4 7.9 6.8 0.59 11.0 1.1 2.4 2 2 0 2 2 2 0 Plant ATP synthase F0 rRNA_processing PF08524.11 OEU07497.1 - 1.9e-08 34.5 31.5 1.9e-08 34.5 31.5 3.5 1 1 3 4 4 4 2 rRNA processing IQ PF00612.27 OEU07498.1 - 0.0044 16.7 0.9 0.0099 15.6 0.0 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif Raftlin PF15250.6 OEU07498.1 - 0.042 12.6 2.9 0.055 12.2 2.9 1.2 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 OEU07498.1 - 1.7 7.3 4.3 2.2 7.0 4.3 1.3 1 0 0 1 1 1 0 Presenilin rve PF00665.26 OEU07499.1 - 3e-05 24.2 0.0 0.00097 19.3 0.0 3.1 3 1 1 4 4 4 2 Integrase core domain Retrotran_gag_2 PF14223.6 OEU07499.1 - 0.013 15.1 2.1 0.017 14.8 0.1 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type IFT20 PF14931.6 OEU07499.1 - 0.022 14.9 2.1 0.063 13.5 2.1 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Serglycin PF04360.12 OEU07499.1 - 0.38 10.7 2.6 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Serglycin TTD PF12148.8 OEU07500.1 - 0.0039 17.1 0.2 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Tandem tudor domain within UHRF1 IQ PF00612.27 OEU07500.1 - 0.012 15.3 0.6 0.028 14.2 0.6 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif SET PF00856.28 OEU07501.1 - 1e-05 26.0 0.1 8.6e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 SET domain DUF3290 PF11694.8 OEU07501.1 - 0.041 13.9 1.7 7 6.6 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) GP120 PF00516.18 OEU07501.1 - 0.1 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 Methyltrans_RNA PF04452.14 OEU07502.1 - 1.1e-22 80.5 6.0 4.3e-15 55.7 1.5 4.1 2 1 0 2 2 2 2 RNA methyltransferase rRNA_methylase PF06962.12 OEU07502.1 - 0.13 12.2 0.1 0.9 9.5 0.1 2.2 1 1 0 1 1 1 0 Putative rRNA methylase DUF1115 PF06544.12 OEU07502.1 - 0.27 11.3 2.8 0.74 9.9 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1115) S-AdoMet_synt_C PF02773.16 OEU07503.1 - 2.2e-62 209.1 0.0 4.1e-62 208.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OEU07503.1 - 6.6e-40 136.1 0.0 1.4e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OEU07503.1 - 1.1e-37 128.6 0.2 3.6e-37 127.0 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amdase PF17645.1 OEU07503.1 - 0.097 12.3 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Arylmalonate decarboxylase Ribosomal_L24e PF01246.20 OEU07504.1 - 0.014 15.6 0.2 3.5 7.9 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L24e DUF4790 PF16037.5 OEU07506.1 - 0.78 10.2 4.9 1.4 9.4 2.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) MRP-S32 PF10210.9 OEU07506.1 - 3.7 8.2 6.7 0.65 10.6 0.9 2.9 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 ABC1 PF03109.16 OEU07509.1 - 4.1e-22 78.6 0.0 7.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU07509.1 - 2e-06 27.9 0.2 3.5e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU07509.1 - 0.034 13.5 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain LON_substr_bdg PF02190.16 OEU07510.1 - 9.6e-15 55.0 0.1 1.6e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 OEU07510.1 - 9.7e-07 29.0 0.3 3.1e-06 27.3 0.3 1.8 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PI3_PI4_kinase PF00454.27 OEU07511.1 - 4.3e-14 52.9 0.5 4.5e-13 49.6 0.1 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Spc42p PF11544.8 OEU07511.1 - 0.03 14.3 0.1 0.03 14.3 0.1 2.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p FA_desaturase PF00487.24 OEU07512.1 - 2.3e-24 86.6 25.5 4.2e-24 85.8 25.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OEU07512.1 - 0.00058 20.1 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pro_isomerase PF00160.21 OEU07513.1 - 2.8e-19 69.9 0.0 3.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M11 PF05548.11 OEU07514.1 - 2.4e-05 23.6 0.0 4.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M11 PF05548.11 OEU07515.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Gametolysin peptidase M11 SelR PF01641.18 OEU07516.1 - 4.3e-44 149.5 0.0 5.1e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 OEU07516.1 - 0.0057 16.8 0.1 0.012 15.8 0.1 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 OEU07516.1 - 0.0058 16.1 0.7 2.5 7.7 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 OEU07516.1 - 0.028 14.2 0.2 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein APH PF01636.23 OEU07518.1 - 9.6e-08 32.2 2.0 0.0012 18.8 0.3 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Zip PF02535.22 OEU07518.1 - 0.61 9.2 1.7 0.87 8.7 1.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Sel1 PF08238.12 OEU07519.1 - 7.7e-07 29.6 0.1 4.5e-05 24.0 0.0 2.5 3 0 0 3 3 3 1 Sel1 repeat Phage_P2_GpE PF06528.12 OEU07519.1 - 0.38 10.4 4.3 0.57 9.8 0.5 2.5 2 0 0 2 2 2 0 Phage P2 GpE SET PF00856.28 OEU07520.1 - 3.2e-12 47.2 0.0 1.2e-11 45.3 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF4919 PF16266.5 OEU07520.1 - 0.063 13.2 0.3 0.64 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) PABP PF00658.18 OEU07521.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain HD_3 PF13023.6 OEU07522.1 - 2.3e-40 138.2 0.9 2.6e-40 138.1 0.0 1.5 2 0 0 2 2 2 1 HD domain HD_2 PF12917.7 OEU07522.1 - 1.1e-12 48.1 0.3 2.6e-12 46.9 0.3 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OEU07522.1 - 7.3e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 HD domain Pinin_SDK_N PF04697.13 OEU07522.1 - 0.099 13.3 2.0 0.17 12.6 2.0 1.5 1 1 0 1 1 1 0 pinin/SDK conserved region Pkinase PF00069.25 OEU07523.1 - 1.3e-17 64.0 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU07523.1 - 7.7e-12 45.0 0.0 2.2e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU07523.1 - 0.015 14.7 0.1 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like PH_12 PF16457.5 OEU07523.1 - 0.085 13.4 0.2 0.26 11.8 0.2 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Trypsin PF00089.26 OEU07524.1 - 1.6e-32 113.1 0.2 2.6e-32 112.4 0.2 1.3 1 0 0 1 1 1 1 Trypsin Fea1 PF07692.11 OEU07526.1 - 1e-20 74.1 30.4 1.5e-07 30.8 0.3 7.3 7 1 0 7 7 7 5 Low iron-inducible periplasmic protein Cytochrome_CBB3 PF13442.6 OEU07527.1 - 4.1e-17 62.2 0.1 7e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OEU07527.1 - 2.3e-08 35.0 0.7 9.5e-08 33.1 0.7 1.9 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 OEU07527.1 - 4.7e-08 32.8 0.1 1.2e-05 25.1 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c-550 domain TMEM65 PF10507.9 OEU07528.1 - 6.2e-44 148.4 4.8 9.6e-44 147.8 4.8 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 Bap31 PF05529.12 OEU07528.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF3789 PF12664.7 OEU07528.1 - 3.6 7.4 11.6 3.3 7.5 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3789) DUF4730 PF15873.5 OEU07528.1 - 5.5 7.3 7.7 2 8.8 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) 2OG-FeII_Oxy_3 PF13640.6 OEU07529.1 - 1.4e-05 25.9 0.0 3.8e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MMU163 PF17119.5 OEU07531.1 - 6.5 5.8 19.7 0.035 13.3 0.6 2.9 2 1 1 3 3 3 0 Mitochondrial protein up-regulated during meiosis V-ATPase_G PF03179.15 OEU07532.1 - 1.3e-23 83.5 1.8 1.6e-23 83.2 1.8 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit WGR PF05406.15 OEU07533.1 - 0.078 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 WGR domain Phage_TTP_13 PF16463.5 OEU07533.1 - 0.087 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage tail tube protein family dUTPase PF00692.19 OEU07535.1 - 6.8e-41 139.0 0.0 7.8e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase Yae1_N PF09811.9 OEU07538.1 - 2.5 7.9 74.6 0.48 10.2 0.4 15.2 12 4 2 14 14 14 0 Essential protein Yae1, N terminal PT PF04886.12 OEU07539.1 - 4.1e-09 35.8 29.8 6.4e-06 25.6 15.7 3.9 1 1 2 3 3 3 2 PT repeat PT PF04886.12 OEU07540.1 - 0.0041 16.6 152.8 5 6.8 20.6 9.0 1 1 4 5 5 5 4 PT repeat MLD PF11647.8 OEU07542.1 - 0.044 14.1 0.4 0.08 13.2 0.4 1.5 1 1 0 1 1 1 0 Membrane Localization Domain FtsH_ext PF06480.15 OEU07542.1 - 1.3 9.4 3.8 45 4.4 3.8 2.2 1 1 0 1 1 1 0 FtsH Extracellular Methyltransf_31 PF13847.6 OEU07544.1 - 6.1e-08 32.6 0.2 1.9e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU07544.1 - 1.1e-07 32.5 0.0 2.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU07544.1 - 9.9e-07 29.3 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU07544.1 - 9.6e-06 26.3 3.6 4.7e-05 24.1 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain ATAD4 PF15321.6 OEU07544.1 - 0.65 11.4 7.1 0.54 11.6 0.6 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 MoaC PF01967.21 OEU07545.1 - 1e-45 155.2 0.1 1.3e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 MoaC family Radical_SAM PF04055.21 OEU07547.1 - 4.8e-08 33.6 0.0 1.1e-07 32.4 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 OEU07547.1 - 0.0023 18.1 0.0 0.0055 16.8 0.0 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Acetyltransf_10 PF13673.7 OEU07548.1 - 6.5e-09 35.8 0.0 0.0035 17.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU07548.1 - 3.6e-06 27.2 0.0 0.0096 16.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 OEU07548.1 - 1.8e-05 24.6 0.0 0.027 14.5 0.0 2.5 3 0 0 3 3 3 2 FR47-like protein Acetyltransf_7 PF13508.7 OEU07548.1 - 0.00066 20.0 0.0 0.0025 18.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Paf1 PF03985.13 OEU07550.1 - 0.041 12.9 0.5 0.056 12.4 0.5 1.1 1 0 0 1 1 1 0 Paf1 Fasciclin PF02469.22 OEU07551.1 - 1.5e-32 112.5 0.1 1.8e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain Orf78 PF06024.12 OEU07552.1 - 0.87 9.9 0.0 0.87 9.9 0.0 3.1 2 0 0 2 2 2 0 Orf78 (ac78) TPR_20 PF14561.6 OEU07553.1 - 0.011 16.0 0.5 0.022 15.1 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.28 OEU07554.1 - 0.0005 20.5 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 SET domain SF3b10 PF07189.11 OEU07556.1 - 1.3e-32 111.8 0.0 1.5e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Fasciclin PF02469.22 OEU07557.1 - 9.7e-68 226.3 0.1 8.8e-33 113.2 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF4097 PF13349.6 OEU07557.1 - 0.0039 16.6 1.6 1.4 8.2 0.1 2.1 2 0 0 2 2 2 2 Putative adhesin HrcA_DNA-bdg PF03444.15 OEU07557.1 - 0.013 15.2 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Phage_sheath_1N PF17481.2 OEU07557.1 - 0.1 13.1 2.8 0.45 11.0 0.3 2.3 2 0 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain PLAC8 PF04749.17 OEU07558.1 - 8e-15 55.6 11.4 1.1e-14 55.2 11.4 1.2 1 0 0 1 1 1 1 PLAC8 family FA_desaturase PF00487.24 OEU07558.1 - 0.18 11.6 0.2 0.35 10.7 0.1 1.5 2 0 0 2 2 2 0 Fatty acid desaturase NAD_binding_10 PF13460.6 OEU07560.1 - 8.6e-21 74.7 0.0 6.7e-19 68.5 0.0 3.1 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 OEU07560.1 - 0.02 15.0 0.1 0.074 13.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 OEU07560.1 - 0.023 14.2 0.0 0.089 12.2 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family ShK PF01549.24 OEU07562.1 - 0.013 16.0 2.5 0.013 16.0 2.5 2.1 2 0 0 2 2 2 0 ShK domain-like CG-1 PF03859.16 OEU07562.1 - 0.063 13.1 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 CG-1 domain Peptidase_A22B PF04258.13 OEU07563.1 - 1e-21 77.7 3.4 3.1e-21 76.1 3.4 1.8 1 1 0 1 1 1 1 Signal peptide peptidase ABC2_membrane_3 PF12698.7 OEU07564.1 - 0.25 10.4 4.9 0.24 10.5 4.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 OEU07564.1 - 0.33 9.7 5.6 0.34 9.6 5.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.6 OEU07564.1 - 0.76 9.8 5.9 0.82 9.7 5.9 1.0 1 0 0 1 1 1 0 CoA-binding domain DUF4131 PF13567.6 OEU07564.1 - 3.5 7.2 14.1 4.5 6.9 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) P2_N PF18628.1 OEU07567.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain Methyltransf_11 PF08241.12 OEU07568.1 - 1.6e-18 67.1 0.0 3.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU07568.1 - 2.5e-15 57.0 0.0 8.6e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU07568.1 - 4.8e-13 49.0 0.0 1.5e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU07568.1 - 2e-12 47.2 0.0 5.4e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU07568.1 - 1.2e-10 41.5 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU07568.1 - 2.2e-09 37.9 0.0 4.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CobA_CobO_BtuR PF02572.15 OEU07571.1 - 2.5e-53 180.9 0.3 3.1e-53 180.5 0.3 1.1 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PHD PF00628.29 OEU07572.1 - 0.00011 22.0 8.0 0.00038 20.3 8.0 2.0 1 0 0 1 1 1 1 PHD-finger PDZ PF00595.24 OEU07572.1 - 0.0024 18.2 0.0 3 8.3 0.0 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 OEU07572.1 - 0.14 12.0 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 PDZ domain Acyl_transf_3 PF01757.22 OEU07574.1 - 8.9e-20 71.0 32.3 8.9e-20 71.0 32.3 2.2 2 1 0 2 2 2 1 Acyltransferase family Peptidase_C74 PF12387.8 OEU07574.1 - 0.37 10.2 4.8 3.9 6.9 0.2 2.5 2 0 0 2 2 2 0 Pestivirus NS2 peptidase DUF4668 PF15701.5 OEU07575.1 - 0.036 13.9 0.3 8.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) YrhK PF14145.6 OEU07575.1 - 0.17 11.8 14.4 1.3 9.0 1.5 4.1 3 1 0 3 3 3 0 YrhK-like protein Voltage_CLC PF00654.20 OEU07578.1 - 1.3e-89 300.9 14.9 1.3e-89 300.9 14.9 1.5 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OEU07578.1 - 2.1e-09 37.7 0.2 0.00096 19.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain LRR_4 PF12799.7 OEU07579.1 - 0.042 14.3 0.4 0.14 12.6 0.4 1.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU07579.1 - 0.094 13.3 1.2 2 9.2 1.2 2.7 1 1 0 1 1 1 0 Leucine Rich Repeat Helicase_C_4 PF13871.6 OEU07580.1 - 8.3e-83 278.2 2.5 8.3e-74 248.7 0.7 2.3 1 1 1 2 2 2 2 C-terminal domain on Strawberry notch homologue Helicase_C PF00271.31 OEU07580.1 - 0.0029 17.9 0.6 0.041 14.2 0.2 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain CIDE-N PF02017.15 OEU07582.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 CIDE-N domain Glyco_tranf_2_4 PF13704.6 OEU07583.1 - 0.00051 20.5 1.1 0.0053 17.2 1.1 2.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 PLAC8 PF04749.17 OEU07584.1 - 1.9e-12 48.1 21.6 1.9e-11 44.8 21.6 2.2 1 1 0 1 1 1 1 PLAC8 family TYW3 PF02676.14 OEU07586.1 - 7.5e-34 117.0 0.2 1e-16 61.0 0.0 2.9 2 1 1 3 3 3 2 Methyltransferase TYW3 Kelch_5 PF13854.6 OEU07586.1 - 1.4e-07 31.3 3.8 0.13 12.2 0.0 5.9 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.6 OEU07586.1 - 7.6e-06 25.8 4.8 0.32 11.0 0.1 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain DUF4833 PF16117.5 OEU07586.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4833) PLDc PF00614.22 OEU07586.1 - 0.44 10.8 3.9 5.8 7.3 0.1 3.6 3 0 0 3 3 3 0 Phospholipase D Active site motif GRP PF07172.11 OEU07587.1 - 6.3e-05 23.6 3.1 6.3e-05 23.6 3.1 3.8 4 0 0 4 4 4 2 Glycine rich protein family DUF4690 PF15756.5 OEU07587.1 - 0.13 12.8 0.0 0.42 11.2 0.0 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage ICE2 PF08426.10 OEU07587.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 1 0 1 1 1 0 ICE2 IMP2_N PF18590.1 OEU07588.1 - 1.8e-17 63.6 0.0 1.9e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 OEU07588.1 - 0.0027 17.5 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain INCENP_ARK-bind PF03941.15 OEU07589.1 - 3.1 7.8 10.5 0.12 12.3 2.9 2.5 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region HSP90 PF00183.18 OEU07592.1 - 1.6e-107 360.6 0.2 3.5e-102 343.0 0.0 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 OEU07592.1 - 2e-11 43.9 1.3 4.6e-11 42.7 1.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OEU07592.1 - 8.2e-10 39.2 0.3 1.6e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Asp PF00026.23 OEU07593.1 - 0.012 15.1 0.1 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic aspartyl protease DUF1533 PF07550.11 OEU07593.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) DUF1108 PF06531.11 OEU07593.1 - 0.11 12.8 1.6 0.24 11.8 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) PALP PF00291.25 OEU07594.1 - 5.9e-48 163.8 0.0 7.1e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 OEU07594.1 - 0.081 12.9 0.0 2 8.4 0.0 2.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Peptidase_M14 PF00246.24 OEU07595.1 - 1.4e-14 54.6 0.0 6.6e-14 52.4 0.0 2.2 2 1 1 3 3 3 1 Zinc carboxypeptidase AstE_AspA PF04952.14 OEU07595.1 - 0.15 11.1 0.1 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family MlaE PF02405.16 OEU07596.1 - 5.1e-18 65.5 1.5 5.5e-18 65.4 1.5 1.0 1 0 0 1 1 1 1 Permease MlaE ABC_tran PF00005.27 OEU07597.1 - 2.7e-21 76.5 0.0 3.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU07597.1 - 0.01 15.7 0.1 0.22 11.3 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU07597.1 - 0.033 14.1 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 OEU07597.1 - 0.05 14.1 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OEU07597.1 - 0.073 13.5 0.3 0.18 12.2 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OEU07597.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain LRR_6 PF13516.6 OEU07598.1 - 3.2e-09 36.1 4.6 0.013 15.5 0.3 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OEU07598.1 - 2.7e-05 24.1 6.2 4.4 8.2 0.1 5.7 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.7 OEU07598.1 - 0.063 13.7 21.8 1.9 9.1 0.0 6.1 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) DUF2116 PF09889.9 OEU07599.1 - 0.38 10.8 2.0 1.3 9.1 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) HrpB_C PF08482.10 OEU07601.1 - 3.1e-22 79.4 0.0 6.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal DEAD PF00270.29 OEU07601.1 - 2.4e-12 47.0 0.1 5e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 OEU07601.1 - 4.3e-07 30.2 6.6 2e-06 28.1 0.0 3.3 4 0 0 4 4 4 1 Helicase associated domain (HA2) AAA_19 PF13245.6 OEU07601.1 - 0.00048 20.5 0.0 0.00099 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OEU07601.1 - 0.00069 19.6 0.0 0.0028 17.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OEU07601.1 - 0.0014 18.4 2.0 0.0037 17.1 2.0 1.7 1 1 0 1 1 1 1 AAA domain Chloroa_b-bind PF00504.21 OEU07602.1 - 1.2e-35 123.4 0.0 1.6e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATP-synt_8 PF00895.20 OEU07604.1 - 0.0012 19.2 1.1 0.0024 18.3 1.1 1.4 1 0 0 1 1 1 1 ATP synthase protein 8 DUF1345 PF07077.11 OEU07604.1 - 0.004 16.9 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) BatD PF13584.6 OEU07604.1 - 0.0053 15.6 0.0 0.0062 15.4 0.0 1.0 1 0 0 1 1 1 1 Oxygen tolerance Orf78 PF06024.12 OEU07604.1 - 0.0061 16.8 2.4 0.0061 16.8 2.4 1.8 1 1 1 2 2 2 1 Orf78 (ac78) Comm PF15957.5 OEU07604.1 - 0.0087 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Commissureless SID-1_RNA_chan PF13965.6 OEU07604.1 - 0.011 14.1 0.1 0.012 14.0 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ac76 PF05814.11 OEU07604.1 - 0.013 15.5 0.6 0.023 14.7 0.5 1.4 1 1 0 1 1 1 0 Orf76 (Ac76) DUF2615 PF11027.8 OEU07604.1 - 0.042 14.0 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Peptidase_M14 PF00246.24 OEU07605.1 - 3.2e-14 53.4 1.8 5.3e-14 52.7 0.0 2.4 2 2 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 OEU07605.1 - 0.00093 18.4 0.3 0.17 10.9 0.0 2.5 3 0 0 3 3 3 2 Succinylglutamate desuccinylase / Aspartoacylase family DUF1622 PF07784.11 OEU07606.1 - 1.8e-12 47.0 0.4 4.5e-12 45.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1622) Zip PF02535.22 OEU07606.1 - 0.00024 20.4 1.1 0.00031 20.1 0.6 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3556 PF12077.8 OEU07607.1 - 1.6e-27 96.2 1.9 2.3e-26 92.4 1.9 2.0 1 1 0 1 1 1 1 Transmembrane protein of unknown function (DUF3556) RsfS PF02410.15 OEU07607.1 - 0.013 15.9 0.0 0.13 12.7 0.0 2.2 1 1 0 1 1 1 0 Ribosomal silencing factor during starvation DUF3955 PF13127.6 OEU07607.1 - 0.18 11.7 8.5 0.14 12.0 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) Glyco_hydro_2_C PF02836.17 OEU07608.1 - 2e-29 102.7 0.2 5e-29 101.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 OEU07608.1 - 0.0013 19.4 0.2 0.0013 19.4 0.2 3.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Spore_YhcN_YlaJ PF09580.10 OEU07608.1 - 0.019 15.1 0.3 0.019 15.1 0.3 3.1 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Glyco_hydro_2_N PF02837.18 OEU07608.1 - 0.03 14.2 1.4 0.71 9.8 0.1 3.2 3 0 0 3 3 3 0 Glycosyl hydrolases family 2, sugar binding domain Connexin PF00029.19 OEU07608.1 - 0.2 11.4 2.8 8.5 6.1 1.1 2.6 2 0 0 2 2 2 0 Connexin Ferlin_C PF16165.5 OEU07608.1 - 0.2 11.6 2.0 0.97 9.4 0.6 2.4 2 0 0 2 2 2 0 Ferlin C-terminus EOS1 PF12326.8 OEU07608.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.8 2 2 0 2 2 2 0 N-glycosylation protein BTB PF00651.31 OEU07609.1 - 6.9e-13 48.8 1.6 1e-12 48.3 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB_2 PF02214.22 OEU07609.1 - 0.00077 19.8 0.5 0.0036 17.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain SAP PF02037.27 OEU07609.1 - 0.00095 18.9 1.0 0.014 15.2 0.4 2.4 2 0 0 2 2 2 1 SAP domain BACK PF07707.15 OEU07609.1 - 0.034 14.2 0.0 7.1 6.8 0.0 2.9 2 1 1 3 3 3 0 BTB And C-terminal Kelch MATH PF00917.26 OEU07609.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 MATH domain Methyltransf_12 PF08242.12 OEU07610.1 - 1.8e-06 28.6 1.6 6.2e-05 23.7 0.1 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU07610.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU07610.1 - 0.00015 22.4 0.0 0.01 16.5 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU07610.1 - 0.0073 16.1 0.7 0.04 13.7 0.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU07610.1 - 0.033 14.8 0.0 1.2 9.9 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 OEU07610.1 - 0.097 12.0 0.0 0.73 9.1 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain SurA_N_2 PF13623.6 OEU07611.1 - 0.006 16.5 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 SurA N-terminal domain HIG_1_N PF04588.13 OEU07611.1 - 0.039 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DUF4886 PF16227.5 OEU07612.1 - 0.00033 19.9 0.0 0.12 11.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4886) DUF2967 PF11179.8 OEU07612.1 - 0.99 7.4 7.8 0.94 7.5 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) E_Pc_C PF06752.12 OEU07612.1 - 4.9 7.2 13.5 2.7 8.0 9.0 2.4 3 0 0 3 3 3 0 Enhancer of Polycomb C-terminus Notch PF00066.17 OEU07613.1 - 5.5e-10 39.5 40.0 0.00032 21.1 3.3 4.2 4 0 0 4 4 4 3 LNR domain Zip PF02535.22 OEU07615.1 - 0.27 10.4 0.3 0.79 8.9 0.0 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Glyco_transf_8 PF01501.20 OEU07617.1 - 4.2e-07 29.8 5.2 7.9e-05 22.3 0.1 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 8 CAP_N PF01213.19 OEU07617.1 - 0.11 12.0 7.7 0.11 11.9 0.6 2.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal WBP-1 PF11669.8 OEU07617.1 - 1.5 9.5 3.3 3.6 8.3 0.0 3.2 3 0 0 3 3 3 0 WW domain-binding protein 1 FKBP_C PF00254.28 OEU07618.1 - 3.2e-08 33.8 0.0 6.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Amino_oxidase PF01593.24 OEU07619.1 - 2.8e-12 46.7 0.0 5.7e-07 29.2 0.0 2.3 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU07619.1 - 1e-09 38.5 0.1 2.8e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU07619.1 - 9.2e-06 25.1 0.3 0.0049 16.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU07619.1 - 0.00012 21.8 0.1 0.0034 17.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OEU07619.1 - 0.00037 20.5 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 OEU07619.1 - 0.0028 16.9 0.2 0.0028 16.9 0.2 2.1 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 OEU07619.1 - 0.14 10.8 0.1 9 4.9 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 OEU07619.1 - 0.24 12.0 0.5 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 OEU07620.1 - 3.7e-25 87.9 0.0 4.2e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU07620.1 - 9.4e-07 29.3 0.0 6.9e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU07620.1 - 4e-05 23.9 0.0 0.0076 16.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 OEU07620.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OEU07620.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 OEU07620.1 - 0.0016 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.10 OEU07620.1 - 0.07 12.8 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 OEU07620.1 - 0.088 13.0 0.1 0.17 12.1 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 OEU07620.1 - 0.091 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_6 PF13848.6 OEU07620.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain TBP PF00352.21 OEU07621.1 - 3.3e-58 193.6 0.2 7.4e-30 102.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OEU07621.1 - 0.0074 16.4 0.0 0.58 10.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) GST_N_2 PF13409.6 OEU07622.1 - 6.2e-20 71.3 0.0 1.3e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU07622.1 - 2.2e-08 34.0 0.0 1.4e-07 31.5 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU07622.1 - 8.1e-06 26.0 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU07622.1 - 0.00013 22.1 0.1 0.00025 21.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OEU07622.1 - 0.005 17.2 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain FSH1 PF03959.13 OEU07622.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Pro_isomerase PF00160.21 OEU07623.1 - 9.2e-05 22.8 0.3 0.00018 21.8 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MAP17 PF15807.5 OEU07623.1 - 0.49 10.6 3.4 0.18 12.1 0.3 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PAS_9 PF13426.7 OEU07624.1 - 9.1e-17 61.2 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 OEU07624.1 - 1.4e-05 25.2 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OEU07624.1 - 0.044 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 OEU07624.1 - 0.074 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS_5 PF07310.13 OEU07624.1 - 0.075 12.8 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 PAS domain HCO3_cotransp PF00955.21 OEU07625.1 - 4.1e-95 319.5 11.7 3.5e-49 168.0 1.4 2.2 1 1 1 2 2 2 2 HCO3- transporter family YtpI PF14007.6 OEU07625.1 - 1.8 8.7 5.8 3.3 7.9 3.5 2.8 2 1 0 2 2 2 0 YtpI-like protein AAA PF00004.29 OEU07626.1 - 2.7e-30 105.5 0.0 9.3e-30 103.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU07626.1 - 3.9e-06 26.6 0.1 9.4e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OEU07626.1 - 0.00058 20.3 0.2 0.0028 18.1 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OEU07626.1 - 0.002 18.1 0.1 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU07626.1 - 0.014 15.6 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OEU07626.1 - 0.051 14.1 0.0 0.051 14.1 0.0 2.9 2 1 0 2 2 1 0 ABC transporter Mg_chelatase PF01078.21 OEU07626.1 - 0.058 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OEU07626.1 - 0.062 13.5 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU07626.1 - 0.089 12.7 0.5 0.66 9.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain DUF5473 PF17567.2 OEU07626.1 - 0.21 11.9 10.8 0.11 12.8 3.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5473) TFIIA PF03153.13 OEU07626.1 - 9.7 6.1 35.0 1 9.3 28.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Yae1_N PF09811.9 OEU07627.1 - 3.1e-08 33.2 63.8 2.4 7.9 0.3 15.5 2 1 8 10 10 10 7 Essential protein Yae1, N terminal MspA PF09203.11 OEU07627.1 - 2.5 7.9 9.8 2.3e+03 -1.7 0.0 4.4 1 1 1 2 2 2 0 MspA PT PF04886.12 OEU07628.1 - 2.8e-06 26.8 21.9 0.093 12.3 5.3 3.0 1 1 1 2 2 2 2 PT repeat Flexi_CP_N PF08358.10 OEU07628.1 - 0.44 10.6 3.1 0.86 9.6 0.6 2.3 1 1 2 3 3 3 0 Carlavirus coat PT PF04886.12 OEU07629.1 - 0.0001 21.8 27.7 0.1 12.2 12.7 3.7 1 1 1 2 2 2 2 PT repeat TPR_2 PF07719.17 OEU07630.1 - 0.012 15.7 0.2 8.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat VasI PF11319.8 OEU07630.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 TPR_7 PF13176.6 OEU07630.1 - 0.021 14.8 2.9 2.2 8.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU07630.1 - 0.13 12.6 0.5 5 7.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU07630.1 - 2.7 8.0 4.5 6 6.9 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Trigger_N PF05697.13 OEU07631.1 - 7e-06 26.4 0.4 1.3e-05 25.6 0.1 1.7 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) NAD_binding_1 PF00175.21 OEU07632.1 - 1.6e-11 44.8 0.0 2.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU07632.1 - 0.00023 21.4 0.0 0.00044 20.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OEU07632.1 - 0.0094 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Sugar_tr PF00083.24 OEU07633.1 - 9.5e-09 34.6 1.3 9.5e-09 34.6 1.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Nepo_coat PF03391.15 OEU07633.1 - 0.015 14.7 0.1 0.045 13.2 0.1 1.7 1 0 0 1 1 1 0 Nepovirus coat protein, central domain PAE PF03283.13 OEU07635.1 - 4e-15 55.8 1.9 7.3e-11 41.8 0.1 2.5 2 1 0 2 2 2 2 Pectinacetylesterase Secretin_N_2 PF07655.13 OEU07635.1 - 9.8 6.8 23.5 0.2 12.2 2.7 3.3 3 0 0 3 3 3 0 Secretin N-terminal domain Ank_2 PF12796.7 OEU07638.1 - 5.1e-06 27.0 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU07638.1 - 0.00057 20.4 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU07638.1 - 0.0021 18.3 0.1 0.077 13.3 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PDZ_6 PF17820.1 OEU07638.1 - 0.015 15.1 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Ank_3 PF13606.6 OEU07638.1 - 0.02 15.4 0.0 0.16 12.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat PDZ_2 PF13180.6 OEU07638.1 - 0.085 13.2 0.2 0.33 11.3 0.2 2.0 1 0 0 1 1 1 0 PDZ domain Vps39_1 PF10366.9 OEU07638.1 - 0.61 10.4 5.4 0.84 9.9 2.9 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Methyltransf_16 PF10294.9 OEU07639.1 - 7.2e-16 58.4 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OEU07639.1 - 0.00014 21.5 0.2 0.00024 20.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OEU07639.1 - 0.0005 20.8 0.1 0.0013 19.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain VPR PF00522.18 OEU07639.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 VPR/VPX protein Helicase_C PF00271.31 OEU07640.1 - 2.2e-18 66.6 0.0 4.3e-18 65.7 0.0 1.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UBA_4 PF14555.6 OEU07641.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 UBA-like domain ARGLU PF15346.6 OEU07642.1 - 0.0098 15.8 13.5 0.016 15.1 13.5 1.4 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 DUF2797 PF10977.8 OEU07642.1 - 0.077 12.9 2.9 0.13 12.1 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) TMPIT PF07851.13 OEU07642.1 - 0.66 9.2 8.0 0.99 8.6 8.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 OEU07642.1 - 6.3 4.6 7.9 6 4.6 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans PF00520.31 OEU07643.1 - 3.5e-37 127.9 23.6 4.7e-37 127.5 23.6 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OEU07643.1 - 1.5e-05 23.9 7.6 1.5e-05 23.9 7.6 2.1 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 OEU07644.1 - 7e-37 127.0 28.8 8e-37 126.8 28.8 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OEU07644.1 - 0.00038 19.3 21.6 0.012 14.3 11.2 2.2 1 1 1 2 2 2 2 Polycystin cation channel Collectrin PF16959.5 OEU07644.1 - 5.6 6.7 7.4 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Renal amino acid transporter Gal-3-0_sulfotr PF06990.11 OEU07645.1 - 0.0086 15.0 0.0 0.021 13.7 0.0 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OEU07645.1 - 0.015 15.2 0.7 0.053 13.4 0.7 1.8 1 1 0 1 1 1 0 Sulfotransferase family APG5 PF04106.12 OEU07647.1 - 2.2e-24 86.3 4.0 1.1e-12 48.1 0.2 3.3 3 1 0 3 3 3 2 Autophagy protein Apg5 Zip PF02535.22 OEU07647.1 - 1.4 8.0 5.4 7.9 5.6 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Coilin_N PF15862.5 OEU07647.1 - 3 7.7 13.6 0.8 9.5 3.4 2.7 3 0 0 3 3 3 0 Coilin N-terminus DUF3527 PF12043.8 OEU07647.1 - 4.6 6.7 9.5 7.5 6.0 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) FAM163 PF15069.6 OEU07647.1 - 5.1 7.5 11.0 0.14 12.6 0.4 2.5 2 1 0 2 2 2 0 FAM163 family DDE_Tnp_1_7 PF13843.6 OEU07649.1 - 5e-07 29.3 0.0 0.00025 20.5 0.0 2.5 1 1 1 2 2 2 2 Transposase IS4 DDE_Tnp_1_7 PF13843.6 OEU07650.1 - 8.2e-13 48.4 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 DUF659 PF04937.15 OEU07651.1 - 0.15 11.9 1.2 0.37 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) DUF1156 PF06634.12 OEU07651.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) CCDC14 PF15254.6 OEU07652.1 - 1 8.0 7.9 1.9 7.0 7.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 CIA30 PF08547.12 OEU07654.1 - 1.7e-14 54.1 0.4 2.9e-14 53.4 0.4 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF229 PF02995.17 OEU07655.1 - 1.1e-18 67.1 0.1 1.3e-17 63.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OEU07655.1 - 2.4e-18 66.6 0.5 5.2e-18 65.5 0.5 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU07655.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2208 PF09973.9 OEU07657.1 - 1.2 8.7 7.0 2.8 7.5 0.2 2.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2208) Peptidase_S9 PF00326.21 OEU07658.1 - 6.8e-36 123.7 0.0 1.2e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 OEU07658.1 - 2.8e-06 26.4 1.8 0.00038 19.4 1.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Metallophos PF00149.28 OEU07659.1 - 0.0029 18.1 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PBP1_TM PF14812.6 OEU07659.1 - 0.049 14.0 0.2 0.049 14.0 0.2 3.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CARM1 PF11531.8 OEU07659.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal DUF4022 PF13214.6 OEU07659.1 - 0.15 12.4 0.5 0.27 11.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) VIR_N PF15912.5 OEU07659.1 - 0.16 11.6 8.2 4.3 6.9 3.2 2.7 2 0 0 2 2 2 0 Virilizer, N-terminal Oxidored_molyb PF00174.19 OEU07660.1 - 1.6e-45 154.8 0.0 2.4e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OEU07660.1 - 1.2e-36 125.8 1.0 2e-36 125.1 1.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 OEU07660.1 - 0.077 13.0 1.5 0.3 11.3 0.1 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Diphthamide_syn PF01866.17 OEU07661.1 - 4.4e-61 207.0 0.4 1.7e-34 119.7 0.0 2.7 2 0 0 2 2 2 2 Putative diphthamide synthesis protein YabA PF06156.13 OEU07661.1 - 4.9 7.9 7.3 0.9 10.2 2.9 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF3684 PF12449.8 OEU07662.1 - 0.027 12.3 0.4 0.037 11.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) DUF2206 PF09971.9 OEU07662.1 - 0.23 10.2 3.2 0.31 9.7 3.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF1275 PF06912.11 OEU07663.1 - 3.4e-11 43.4 12.1 5.3e-11 42.8 12.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) EF-hand_6 PF13405.6 OEU07663.1 - 6.8e-05 22.5 0.7 0.019 14.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU07663.1 - 0.00035 21.0 2.2 0.0042 17.5 1.5 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU07663.1 - 0.013 15.0 0.7 0.064 12.8 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 OEU07663.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Fasciclin PF02469.22 OEU07664.1 - 3e-12 46.9 0.0 7.8e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Fasciclin domain CCDC106 PF15794.5 OEU07665.1 - 0.0098 15.6 0.7 0.0098 15.6 0.7 2.1 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 106 Sporozoite_P67 PF05642.11 OEU07665.1 - 0.032 12.3 3.2 0.038 12.1 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 OEU07665.1 - 6.7 6.7 24.2 0.5 10.4 18.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Baculo_PEP_C PF04513.12 OEU07667.1 - 0.011 15.7 2.1 0.011 15.7 2.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 OEU07667.1 - 0.076 13.3 13.1 0.43 10.8 0.4 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 OEU07667.1 - 0.12 11.3 13.7 0.14 11.0 8.7 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 OEU07667.1 - 0.15 11.7 12.3 0.13 12.0 7.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ZapB PF06005.12 OEU07667.1 - 0.16 12.5 0.2 0.16 12.5 0.2 3.1 3 1 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 OEU07667.1 - 0.16 11.8 7.7 0.35 10.7 0.1 3.9 4 0 0 4 4 4 0 Septum formation initiator IFT20 PF14931.6 OEU07667.1 - 0.22 11.7 7.4 1.2 9.3 0.8 2.6 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Atg14 PF10186.9 OEU07667.1 - 0.51 9.4 11.6 0.41 9.7 6.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Hpt PF01627.23 OEU07667.1 - 0.54 10.5 3.3 0.79 10.0 1.3 2.3 1 1 1 2 2 2 0 Hpt domain DUF1664 PF07889.12 OEU07667.1 - 0.67 10.0 6.2 7.2 6.7 1.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GLE1 PF07817.13 OEU07667.1 - 0.81 8.8 4.5 0.74 9.0 0.3 2.3 1 1 1 2 2 2 0 GLE1-like protein Sec8_exocyst PF04048.14 OEU07667.1 - 0.83 9.5 10.9 3.7 7.4 1.6 3.2 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain MerR-DNA-bind PF09278.11 OEU07667.1 - 2.1 8.9 5.7 26 5.5 0.0 3.8 3 1 1 4 4 4 0 MerR, DNA binding HMMR_N PF15905.5 OEU07667.1 - 3.8 6.9 24.2 0.18 11.3 14.7 2.5 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Com_YlbF PF06133.11 OEU07667.1 - 4.9 7.8 9.2 11 6.7 2.8 3.0 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Syntaxin_2 PF14523.6 OEU07667.1 - 5.9 7.3 13.0 1.8 9.0 2.0 3.4 1 1 2 3 3 3 0 Syntaxin-like protein Sec34 PF04136.15 OEU07667.1 - 6.2 6.7 9.0 5.2 6.9 1.5 2.8 1 1 0 2 2 2 0 Sec34-like family APG6_N PF17675.1 OEU07667.1 - 6.7 7.3 20.9 0.23 12.0 0.3 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region PC-Esterase PF13839.6 OEU07668.1 - 2.5e-05 24.2 1.1 0.044 13.5 0.0 2.4 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p HA PF03457.14 OEU07669.1 - 1.7e-33 114.7 0.5 6.8e-16 58.3 0.2 2.0 2 0 0 2 2 2 2 Helicase associated domain Cas9-BH PF16593.5 OEU07669.1 - 0.1 12.3 0.2 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 LST1 PF05083.13 OEU07670.1 - 0.22 11.8 0.0 0.22 11.8 0.0 2.7 3 0 0 3 3 3 0 LST-1 protein ADP_ribosyl_GH PF03747.14 OEU07672.1 - 0.1 12.3 0.1 0.23 11.2 0.0 1.6 1 1 1 2 2 2 0 ADP-ribosylglycohydrolase EBV-NA3 PF05009.12 OEU07672.1 - 0.38 10.2 5.3 2.1 7.8 2.0 2.6 3 0 0 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DDE_Tnp_4 PF13359.6 OEU07674.1 - 0.0042 16.8 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Chalcone_2 PF16035.5 OEU07674.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Chalcone isomerase like PBP1_TM PF14812.6 OEU07675.1 - 5.1 7.5 12.6 4.2 7.8 3.1 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FliD_N PF02465.18 OEU07676.1 - 7.8 7.3 15.6 3.9 8.3 4.1 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF3439 PF11921.8 OEU07676.1 - 8.6 6.4 9.1 21 5.1 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 OEU07676.1 - 9.4 6.2 17.0 1.3 9.0 12.3 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3246 PF11596.8 OEU07678.1 - 0.0027 17.2 1.9 0.0041 16.6 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) DUF2877 PF11392.8 OEU07678.1 - 0.069 13.9 0.7 0.099 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) DUF2718 PF10918.8 OEU07678.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) PIG-P PF08510.12 OEU07678.1 - 0.24 11.3 1.1 0.61 10.0 1.1 1.7 1 1 0 1 1 1 0 PIG-P Comm PF15957.5 OEU07678.1 - 0.3 11.4 3.2 0.52 10.7 3.2 1.5 1 1 0 1 1 1 0 Commissureless DUF1738 PF08401.11 OEU07678.1 - 0.64 10.1 2.5 1.4 9.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1738) TFIIE-A_C PF11521.8 OEU07678.1 - 1.5 9.1 17.3 0.53 10.6 2.4 2.3 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ribosomal_60s PF00428.19 OEU07678.1 - 5 7.8 8.9 1.5 9.5 0.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein FSAP_sig_propep PF03032.15 OEU07678.1 - 7.6 6.7 13.1 2.5 8.2 5.1 2.4 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide SET PF00856.28 OEU07680.1 - 8.3e-08 32.8 0.4 1.8e-07 31.7 0.4 1.7 1 1 0 1 1 1 1 SET domain GTP1_OBG PF01018.22 OEU07682.1 - 0.03 13.9 4.6 3.7 7.1 0.0 3.2 3 0 0 3 3 3 0 GTP1/OBG KorB_C PF06613.11 OEU07682.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain UTP25 PF06862.12 OEU07683.1 - 4.5e-120 401.6 16.7 1.8e-85 287.5 1.5 3.9 3 1 0 3 3 3 3 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4611 PF15387.6 OEU07683.1 - 1.5 9.1 28.0 0.77 10.0 6.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 OEU07683.1 - 6.8 6.4 28.3 16 5.2 8.1 3.5 2 1 1 3 3 3 0 Pox virus Ag35 surface protein DUF3500 PF12006.8 OEU07684.1 - 1.2e-05 24.9 0.0 3.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3500) CLP_protease PF00574.23 OEU07685.1 - 8.8e-47 159.3 0.1 3.1e-46 157.5 0.0 1.9 2 1 0 2 2 2 1 Clp protease adh_short_C2 PF13561.6 OEU07686.1 - 7.8e-51 172.9 0.2 3.8e-50 170.6 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU07686.1 - 1.1e-42 145.7 2.3 3.6e-42 144.0 0.4 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OEU07686.1 - 4.2e-06 26.8 0.1 7.3e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OEU07686.1 - 0.00083 19.3 0.4 0.0018 18.2 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OEU07686.1 - 0.029 13.7 0.1 3.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 OEU07686.1 - 0.074 12.8 0.9 0.38 10.5 0.3 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LRR19-TM PF15176.6 OEU07687.1 - 0.0017 18.3 0.3 0.0017 18.3 0.3 2.3 3 0 0 3 3 3 1 Leucine-rich repeat family 19 TM domain NOA36 PF06524.12 OEU07687.1 - 2.1 7.6 6.9 2.6 7.3 6.9 1.1 1 0 0 1 1 1 0 NOA36 protein STELLO PF03385.17 OEU07689.1 - 5.1e-20 71.6 0.0 7.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases Vps35 PF03635.17 OEU07691.1 - 2.1e-185 618.4 10.8 2.6e-185 618.0 10.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Fer4_2 PF12797.7 OEU07691.1 - 1.8 8.8 3.6 3.6 7.9 0.2 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Mt_ATP-synt_B PF05405.14 OEU07692.1 - 1.6e-11 44.1 3.8 2.7e-11 43.3 3.8 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MAPEG PF01124.18 OEU07693.1 - 1.2e-06 28.5 2.8 2.5e-06 27.4 2.8 1.6 1 0 0 1 1 1 1 MAPEG family Rhodanese PF00581.20 OEU07694.1 - 1.3e-11 44.9 0.0 1.9e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HA PF03457.14 OEU07695.1 - 7.4e-19 67.8 1.2 8.9e-16 58.0 0.8 2.2 2 0 0 2 2 2 2 Helicase associated domain HA PF03457.14 OEU07696.1 - 8.6e-25 86.9 1.0 1.1e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 Helicase associated domain Ribosomal_L14e PF01929.17 OEU07697.1 - 4.1e-28 97.7 7.5 5.3e-28 97.3 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 zf-RING_UBOX PF13445.6 OEU07698.1 - 3.5e-11 42.9 1.8 3.5e-11 42.9 1.8 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU07698.1 - 1.6e-09 37.6 6.7 3.1e-09 36.6 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU07698.1 - 2.7e-09 36.7 5.9 5.3e-09 35.8 5.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OEU07698.1 - 3.7e-09 36.3 3.9 7.5e-09 35.3 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU07698.1 - 4.6e-08 32.8 5.8 1.1e-07 31.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU07698.1 - 7.2e-07 29.4 5.5 7.2e-07 29.4 5.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU07698.1 - 8.5e-07 28.7 9.9 6.4e-06 25.9 10.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU07698.1 - 6.8e-06 26.1 5.8 6.8e-06 26.1 5.8 2.3 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-CCCH PF00642.24 OEU07698.1 - 9.8e-06 25.4 1.4 9.8e-06 25.4 1.4 2.1 3 0 0 3 3 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU07698.1 - 0.00058 19.8 2.8 0.00058 19.8 2.8 2.4 3 0 0 3 3 3 1 Zinc finger domain zf-rbx1 PF12678.7 OEU07698.1 - 0.0087 16.3 4.2 0.11 12.7 4.2 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OEU07698.1 - 0.028 14.5 2.6 0.028 14.5 2.6 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 Gin PF10764.9 OEU07698.1 - 0.03 14.3 1.2 0.03 14.3 1.2 2.2 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-CCCH_4 PF18044.1 OEU07698.1 - 0.36 10.7 6.8 0.08 12.8 2.2 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger zf-P11 PF03854.14 OEU07698.1 - 0.4 10.4 4.8 1.9 8.2 4.8 2.2 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 OEU07698.1 - 1.4 8.7 9.5 1.9 8.3 5.8 2.6 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 OEU07698.1 - 3.3 7.9 7.3 17 5.6 7.3 2.2 1 1 0 1 1 1 0 FYVE zinc finger HA PF03457.14 OEU07700.1 - 3.1e-15 56.2 0.4 6.8e-15 55.1 0.4 1.6 1 0 0 1 1 1 1 Helicase associated domain HA PF03457.14 OEU07701.1 - 1.7e-94 310.2 15.8 1.9e-18 66.6 0.1 6.0 6 0 0 6 6 6 6 Helicase associated domain DUF4250 PF14056.6 OEU07701.1 - 0.0055 16.6 0.0 49 4.0 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4250) DUF1803 PF08820.10 OEU07701.1 - 0.02 14.9 0.3 11 6.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1803) Prp19 PF08606.11 OEU07701.1 - 0.084 12.9 2.7 5.7 7.0 0.0 2.9 3 0 0 3 3 3 0 Prp19/Pso4-like A_thal_3526 PF09713.10 OEU07701.1 - 0.2 11.9 2.1 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) PMR5N PF14416.6 OEU07701.1 - 0.21 11.9 5.1 26 5.2 0.0 4.7 6 0 0 6 6 6 0 PMR5 N terminal Domain TAN PF11640.8 OEU07701.1 - 0.41 10.8 4.7 7.1 6.8 0.2 3.3 2 2 2 4 4 4 0 Telomere-length maintenance and DNA damage repair PRK PF00485.18 OEU07701.1 - 1.3 8.8 4.1 5.7 6.6 0.2 3.1 3 1 1 4 4 4 0 Phosphoribulokinase / Uridine kinase family TRF PF08558.10 OEU07701.1 - 1.5 8.4 6.5 0.86 9.2 0.4 3.1 4 0 0 4 4 4 0 Telomere repeat binding factor (TRF) zf-RVT PF13966.6 OEU07704.1 - 5.4e-06 27.0 1.2 1.4e-05 25.7 1.2 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 OEU07704.1 - 0.12 12.7 1.7 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Transposase zf-C2HCIx2C PF10782.9 OEU07704.1 - 2 8.4 4.9 0.79 9.7 0.1 2.7 3 1 1 4 4 4 0 Zinc-finger DUF3485 PF11984.8 OEU07705.1 - 0.029 14.1 0.2 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) RVT_1 PF00078.27 OEU07706.1 - 0.00016 21.3 0.0 0.0029 17.2 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LBR_tudor PF09465.10 OEU07706.1 - 0.14 12.0 2.5 0.13 12.1 0.5 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF3089 PF11288.8 OEU07707.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PHAT PF09246.10 OEU07708.1 - 0.062 13.1 0.1 0.19 11.5 0.0 1.7 1 1 1 2 2 2 0 PHAT PHM7_cyt PF14703.6 OEU07709.1 - 0.0044 17.3 1.4 0.0051 17.1 1.4 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF957 PF06117.11 OEU07709.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) BNR_2 PF13088.6 OEU07710.1 - 0.08 12.2 0.8 7.8 5.7 0.4 2.8 2 1 0 2 2 2 0 BNR repeat-like domain Macoilin PF09726.9 OEU07711.1 - 0.069 11.7 5.5 0.077 11.5 5.5 1.1 1 0 0 1 1 1 0 Macoilin family Hydrolase_4 PF12146.8 OEU07712.1 - 2.7e-32 112.0 0.0 3.5e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU07712.1 - 9.5e-07 28.5 0.0 0.00011 21.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OEU07712.1 - 2e-05 25.3 0.0 2.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.22 OEU07712.1 - 0.042 13.3 0.1 0.62 9.4 0.0 2.2 2 1 0 2 2 2 0 Serine carboxypeptidase DUF2920 PF11144.8 OEU07712.1 - 0.048 12.8 0.1 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) ZapA PF05164.13 OEU07712.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapA TPR_1 PF00515.28 OEU07713.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU07713.1 - 0.04 14.0 0.9 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU07713.1 - 0.056 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CheR PF01739.18 OEU07713.1 - 0.061 12.8 1.7 0.11 12.0 1.7 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TPR_7 PF13176.6 OEU07713.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC73_C PF05179.14 OEU07713.1 - 0.67 9.6 4.4 2.7 7.7 0.2 2.4 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family, C-terminal Renin_r PF07850.14 OEU07713.1 - 3.1 8.4 5.4 3.1 8.5 0.2 2.7 2 0 0 2 2 2 0 Renin receptor-like protein Pex14_N PF04695.13 OEU07713.1 - 6.4 7.4 7.6 28 5.3 3.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HSF_DNA-bind PF00447.17 OEU07716.1 - 6.7e-06 26.6 0.1 0.00023 21.7 0.0 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding PBP1_TM PF14812.6 OEU07716.1 - 0.68 10.3 8.2 0.14 12.5 3.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gly_transf_sug PF04488.15 OEU07717.1 - 0.065 13.9 0.6 0.72 10.5 0.3 2.4 2 1 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif Glyco_transf_92 PF01697.27 OEU07718.1 - 7.8e-15 55.2 3.4 2e-14 53.9 3.4 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU07718.1 - 2.2e-08 34.5 1.7 2.9e-08 34.1 0.7 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 tRNA_Me_trans PF03054.16 OEU07718.1 - 0.057 12.2 0.1 0.089 11.6 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase FANCL_C PF11793.8 OEU07719.1 - 0.00019 21.5 6.6 0.00054 20.1 6.6 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OEU07719.1 - 0.0003 21.1 11.4 0.00094 19.5 11.4 2.0 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OEU07719.1 - 0.076 13.1 3.5 0.24 11.5 3.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger KCNQ2_u3 PF16642.5 OEU07719.1 - 0.9 10.6 4.8 4.9 8.2 4.8 2.3 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 RINGv PF12906.7 OEU07719.1 - 1.1 9.4 9.4 3.1 8.0 9.4 1.9 1 0 0 1 1 1 0 RING-variant domain zf-piccolo PF05715.13 OEU07719.1 - 1.7 8.9 8.1 5.1 7.3 8.1 1.9 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4 PF00097.25 OEU07719.1 - 1.9 8.4 13.6 1.6 8.6 11.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 OEU07719.1 - 5.1 7.4 9.2 16 5.8 7.0 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain PHD PF00628.29 OEU07719.1 - 5.5 7.0 9.4 21 5.1 9.4 2.1 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 OEU07719.1 - 5.9 7.1 8.1 19 5.5 6.8 2.7 1 1 0 1 1 1 0 PHD-finger Pep1_7 PF17232.2 OEU07719.1 - 6.8 7.2 6.5 19 5.8 1.1 3.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 tRNA_anti-like PF12869.7 OEU07721.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 tRNA_anti-like Oxidored_molyb PF00174.19 OEU07722.1 - 5.1e-53 179.2 0.0 7.6e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OEU07722.1 - 4.4e-24 85.1 1.1 1e-23 83.9 1.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain adh_short PF00106.25 OEU07724.1 - 2.2e-16 59.9 7.5 3.3e-09 36.5 3.0 3.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU07724.1 - 1.1e-12 48.0 1.0 2.2e-05 24.1 2.0 4.0 1 1 2 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU07724.1 - 0.00074 19.5 2.2 0.78 9.6 0.1 2.6 1 1 2 3 3 3 2 KR domain Methyltransf_22 PF13383.6 OEU07725.1 - 1.1e-05 25.1 0.1 1.7e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OEU07725.1 - 0.017 15.2 0.1 0.045 13.8 0.1 1.6 1 1 1 2 2 2 0 Methyltransferase FkbM domain Aldo_ket_red PF00248.21 OEU07725.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family Methyltransf_21 PF05050.12 OEU07726.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_transf_8 PF01501.20 OEU07727.1 - 1.7e-07 31.1 0.7 4e-07 29.9 0.7 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Exostosin PF03016.15 OEU07728.1 - 0.029 13.6 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Exostosin family DUF563 PF04577.14 OEU07731.1 - 1.7e-20 74.1 0.9 1.5e-19 70.9 1.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Sulfate_transp PF00916.20 OEU07732.1 - 5.3e-58 196.6 25.8 8.4e-58 195.9 25.8 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OEU07732.1 - 0.0027 17.3 0.1 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 STAS domain DUF3439 PF11921.8 OEU07732.1 - 0.0053 16.7 1.1 0.0053 16.7 1.1 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3439) Raptor_N PF14538.6 OEU07733.1 - 6.7e-50 168.9 0.0 1.2e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OEU07733.1 - 7.8e-06 26.5 15.5 2.2 9.3 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT_2 PF13646.6 OEU07733.1 - 0.0009 19.6 0.3 3.7 8.0 0.0 3.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 OEU07733.1 - 0.0027 17.8 6.3 1.2 9.6 0.3 4.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 OEU07733.1 - 0.018 15.5 0.3 0.2 12.2 0.0 2.8 3 0 0 3 3 3 0 HEAT-like repeat Atx10homo_assoc PF09759.9 OEU07733.1 - 1.4 9.0 4.7 69 3.6 0.1 4.0 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain LRR_4 PF12799.7 OEU07734.1 - 0.023 15.1 4.0 3.6 8.1 0.1 4.6 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU07734.1 - 0.23 11.2 1.9 8.2 6.3 0.0 3.4 3 1 0 3 3 3 0 Leucine rich repeat DUF2894 PF11445.8 OEU07735.1 - 0.15 12.6 5.6 0.44 11.0 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF3618 PF12277.8 OEU07735.1 - 0.45 10.8 6.6 0.11 12.7 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Adaptin_N PF01602.20 OEU07736.1 - 5e-102 342.1 8.1 6.7e-102 341.7 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OEU07736.1 - 7.1e-48 162.6 2.6 1.8e-47 161.3 1.5 2.3 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OEU07736.1 - 7.1e-31 106.7 0.0 1.5e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OEU07736.1 - 3e-14 53.2 8.7 4.5e-07 30.2 0.1 5.1 4 2 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 OEU07736.1 - 2.3e-09 37.5 7.4 0.0089 16.1 0.3 4.4 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OEU07736.1 - 7.4e-08 32.7 2.7 0.033 14.7 0.4 4.3 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 OEU07736.1 - 5.5e-06 26.2 6.0 4.4 7.8 0.7 6.1 5 0 0 5 5 5 2 HEAT repeat AID PF18767.1 OEU07736.1 - 0.05 13.6 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Activation induced deaminase CitMHS PF03600.16 OEU07738.1 - 0.027 13.7 6.1 0.029 13.6 4.8 1.6 1 1 0 1 1 1 0 Citrate transporter zf-ANAPC11 PF12861.7 OEU07739.1 - 9.4e-31 105.7 4.0 1e-30 105.6 4.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OEU07739.1 - 9.9e-20 70.6 3.4 1.4e-19 70.1 3.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OEU07739.1 - 3.2e-10 40.2 6.3 1.6e-09 38.0 6.3 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU07739.1 - 1.7e-07 30.9 1.1 1.7e-07 30.9 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU07739.1 - 6.4e-07 29.1 2.7 1.9e-06 27.6 2.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU07739.1 - 1.2e-06 28.4 3.8 6.7e-06 26.0 4.6 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU07739.1 - 1.1e-05 25.3 6.0 2.5e-05 24.2 1.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU07739.1 - 1.5e-05 24.8 3.5 7.6e-05 22.5 3.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OEU07739.1 - 0.0004 20.1 0.4 0.0073 16.1 0.2 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OEU07739.1 - 0.0005 19.9 6.2 0.02 14.7 7.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU07739.1 - 0.0015 18.1 1.1 0.0015 18.1 1.1 2.1 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type RecR PF02132.15 OEU07739.1 - 0.0026 17.3 1.6 0.26 10.9 0.1 2.2 2 0 0 2 2 2 1 RecR protein zf-RING_11 PF17123.5 OEU07739.1 - 0.0042 16.8 9.0 0.0051 16.5 4.5 2.8 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 OEU07739.1 - 0.017 15.3 1.9 0.017 15.3 1.9 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OEU07739.1 - 0.021 15.2 1.2 0.021 15.2 1.2 1.7 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 OEU07739.1 - 0.03 14.4 3.5 0.03 14.4 3.5 2.1 2 0 0 2 2 2 0 RING-variant domain zf-Nse PF11789.8 OEU07739.1 - 0.048 13.5 0.9 0.071 12.9 0.9 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OEU07739.1 - 0.43 10.8 8.6 5.7 7.2 8.6 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 OEU07739.1 - 0.46 10.4 6.4 2.4 8.1 6.4 2.1 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_5 PF17121.5 OEU07739.1 - 2.1 8.3 5.8 8.4 6.4 1.1 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF5331 PF17265.2 OEU07740.1 - 0.088 12.5 0.1 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5331) Tub PF01167.18 OEU07740.1 - 6.5 6.4 11.4 0.48 10.1 2.1 2.4 1 1 1 2 2 2 0 Tub family tRNA_anti-like PF12869.7 OEU07741.1 - 0.7 9.5 6.3 0.083 12.5 2.0 1.7 2 0 0 2 2 2 0 tRNA_anti-like potato_inhibit PF00280.18 OEU07742.1 - 4.7e-11 43.2 0.3 2.1e-10 41.1 0.3 2.2 1 0 0 1 1 1 1 Potato inhibitor I family SPRR2 PF14820.6 OEU07742.1 - 2.5 8.2 13.5 16 5.7 0.7 3.6 3 0 0 3 3 3 0 Small proline-rich 2 CBM_1 PF00734.18 OEU07742.1 - 3.3 7.8 11.4 12 6.0 0.5 4.0 3 0 0 3 3 3 0 Fungal cellulose binding domain HIT PF01230.23 OEU07744.1 - 7.1e-18 65.2 0.1 1.5e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OEU07744.1 - 0.00041 20.8 0.1 0.00085 19.8 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF1849 PF08904.11 OEU07744.1 - 0.093 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) SPATA24 PF15175.6 OEU07745.1 - 0.029 14.3 1.9 0.047 13.6 1.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Rep_fac-A_C PF08646.10 OEU07745.1 - 0.064 13.0 1.6 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Replication factor-A C terminal domain CC2-LZ PF16516.5 OEU07745.1 - 0.25 11.8 4.9 0.17 12.3 3.7 1.4 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator p450 PF00067.22 OEU07747.1 - 3.7e-68 230.4 0.0 6.2e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Renin_r PF07850.14 OEU07748.1 - 0.0018 18.8 1.2 0.0023 18.5 0.1 1.7 2 1 0 2 2 2 1 Renin receptor-like protein DUF3899 PF13038.6 OEU07748.1 - 0.047 14.2 0.1 9.2 6.8 0.0 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF3899) Mito_carr PF00153.27 OEU07748.1 - 0.18 11.7 1.4 0.46 10.4 1.4 1.8 1 1 0 1 1 1 0 Mitochondrial carrier protein Serinc PF03348.15 OEU07748.1 - 0.57 9.1 4.4 0.5 9.2 2.8 1.5 1 1 1 2 2 2 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 OEU07749.1 - 1.2e-256 853.7 7.4 8.2e-256 851.0 7.4 2.2 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 OEU07749.1 - 0.032 14.6 2.1 0.059 13.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DASH_Dam1 PF08653.10 OEU07749.1 - 0.058 13.2 0.2 0.19 11.5 0.2 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 ADP_ribosyl_GH PF03747.14 OEU07750.1 - 2.5e-33 116.0 1.3 3.2e-33 115.7 1.3 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TPR_11 PF13414.6 OEU07750.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 TPR repeat ABC_membrane PF00664.23 OEU07751.1 - 1.8e-40 139.3 9.6 2.5e-40 138.9 9.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OEU07751.1 - 3.3e-32 111.9 0.0 5.9e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU07751.1 - 3.5e-06 26.6 2.1 9e-05 22.0 0.2 2.7 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OEU07751.1 - 0.0012 19.0 1.2 0.014 15.6 0.1 2.6 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 OEU07751.1 - 0.0013 18.3 0.9 0.016 14.8 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU07751.1 - 0.0023 18.2 0.4 0.028 14.7 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU07751.1 - 0.0034 17.8 0.0 0.0074 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OEU07751.1 - 0.004 17.1 0.6 3.6 7.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TniB PF05621.11 OEU07751.1 - 0.013 14.9 0.1 0.89 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OEU07751.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OEU07751.1 - 0.026 14.3 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OEU07751.1 - 0.03 14.2 0.6 7.9 6.4 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA PF00004.29 OEU07751.1 - 0.038 14.4 0.9 0.41 11.1 0.9 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 OEU07751.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OEU07751.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OEU07751.1 - 0.13 12.4 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 OEU07751.1 - 0.15 11.8 0.1 1.5 8.6 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DENN PF02141.21 OEU07752.1 - 5.9e-37 127.4 2.1 5.9e-37 127.4 2.1 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OEU07752.1 - 2.1e-10 41.2 3.4 1.3e-09 38.7 3.4 2.4 1 1 0 1 1 1 1 uDENN domain CENP-B_dimeris PF09026.10 OEU07752.1 - 0.011 16.1 5.5 0.6 10.5 1.0 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4813 PF16072.5 OEU07752.1 - 0.11 12.2 11.1 0.039 13.6 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Methyltransf_12 PF08242.12 OEU07752.1 - 0.15 12.8 8.5 20 6.0 0.3 5.0 5 0 0 5 5 5 0 Methyltransferase domain dDENN PF03455.19 OEU07752.1 - 0.88 9.6 5.6 0.12 12.4 0.6 2.3 2 0 0 2 2 2 0 dDENN domain PT PF04886.12 OEU07753.1 - 9.2 5.9 18.5 4.5 6.9 2.4 3.3 3 0 0 3 3 3 0 PT repeat HA PF03457.14 OEU07754.1 - 2.3e-34 117.5 4.8 9.3e-16 57.9 0.1 3.8 3 1 1 4 4 4 3 Helicase associated domain Helicase_IV_N PF12462.8 OEU07754.1 - 0.011 15.7 2.5 0.011 15.7 2.5 1.7 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal Cep57_CLD PF14073.6 OEU07754.1 - 0.13 12.3 0.6 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 BSD PF03909.17 OEU07755.1 - 0.027 14.5 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 BSD domain Mucin PF01456.17 OEU07758.1 - 4.9 7.1 14.1 0.37 10.8 8.5 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein EF-hand_7 PF13499.6 OEU07759.1 - 1.2e-06 28.9 1.1 0.0071 16.8 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU07759.1 - 1.5e-05 24.2 0.2 0.05 13.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU07759.1 - 0.11 12.5 4.9 2.8 8.1 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 OEU07759.1 - 0.21 11.8 1.8 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain Tim17 PF02466.19 OEU07760.1 - 0.2 12.0 0.3 0.2 12.0 0.3 2.2 2 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Baculo_11_kDa PF06143.11 OEU07761.1 - 2.5e-05 23.7 0.2 0.017 14.7 0.1 2.9 2 0 0 2 2 2 2 Baculovirus 11 kDa family Lectin_N PF03954.14 OEU07761.1 - 0.00025 20.8 0.1 0.89 9.3 0.0 2.8 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain DUF872 PF05915.12 OEU07761.1 - 0.043 14.0 0.5 0.29 11.3 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SIT PF15330.6 OEU07761.1 - 0.21 12.0 5.6 2.8 8.4 0.0 4.0 3 1 1 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT DUF5367 PF17329.2 OEU07761.1 - 0.26 11.4 2.7 1.2 9.3 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5367) Zip PF02535.22 OEU07761.1 - 1.2 8.3 0.0 1.2 8.3 0.0 4.1 3 1 0 4 4 4 0 ZIP Zinc transporter CD20 PF04103.15 OEU07761.1 - 7.7 6.6 14.2 31 4.6 2.4 5.0 3 2 1 5 5 5 0 CD20-like family DAGAT PF03982.13 OEU07762.1 - 6.4e-18 64.7 0.0 8.9e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 OEU07762.1 - 0.0096 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SARAF PF06682.12 OEU07763.1 - 0.005 16.5 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SafA PF17073.5 OEU07763.1 - 0.037 14.0 0.2 0.051 13.5 0.2 1.1 1 0 0 1 1 1 0 Two-component-system connector protein CD34_antigen PF06365.12 OEU07763.1 - 0.094 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.6 OEU07763.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 OEU07763.1 - 0.11 12.1 0.4 0.15 11.7 0.4 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Comm PF15957.5 OEU07763.1 - 0.16 12.3 0.1 0.2 12.0 0.1 1.1 1 0 0 1 1 1 0 Commissureless DUF4448 PF14610.6 OEU07763.1 - 0.28 10.9 0.0 0.34 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SET PF00856.28 OEU07767.1 - 6.8e-06 26.6 3.8 0.27 11.6 0.0 5.0 3 2 0 3 3 3 2 SET domain B12D PF06522.11 OEU07769.1 - 6.3e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SARS_lipid_bind PF09399.10 OEU07769.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 1 0 1 1 1 0 SARS lipid binding protein NAD_binding_1 PF00175.21 OEU07770.1 - 6.8e-09 36.3 0.0 1.2e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2781 PF10914.8 OEU07770.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Methyltransf_23 PF13489.6 OEU07771.1 - 0.054 13.3 0.2 0.054 13.3 0.2 2.2 2 1 0 2 2 2 0 Methyltransferase domain FUSC-like PF12805.7 OEU07771.1 - 1.8 7.6 9.4 0.082 12.0 2.2 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS TFIIA PF03153.13 OEU07771.1 - 2.8 7.8 38.0 1.2e+02 2.4 38.3 2.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ant_C PF05586.11 OEU07772.1 - 7.3 7.3 7.5 1.4 9.6 1.5 3.1 2 0 0 2 2 2 0 Anthrax receptor C-terminus region DUF285 PF03382.14 OEU07773.1 - 6.5e-104 342.3 44.2 3.3e-41 139.8 9.6 3.1 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DUF3525 PF12039.8 OEU07773.1 - 0.0021 16.8 2.3 0.18 10.5 0.6 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF3525) TGase_elicitor PF16683.5 OEU07773.1 - 0.026 13.3 8.0 3.3 6.4 0.2 3.9 1 1 3 4 4 4 0 Transglutaminase elicitor PucR PF07905.11 OEU07773.1 - 0.035 14.4 0.0 57 4.0 0.0 3.8 2 2 4 6 6 6 0 Purine catabolism regulatory protein-like family BetR PF08667.10 OEU07773.1 - 0.078 13.0 0.2 42 4.2 0.0 4.2 6 1 0 6 6 6 0 BetR domain U5_2-snRNA_bdg PF10597.9 OEU07773.1 - 0.17 12.0 5.6 39 4.3 0.1 4.5 1 1 4 6 6 6 0 U5-snRNA binding site 2 of PrP8 Foie-gras_1 PF11817.8 OEU07773.1 - 0.39 10.2 6.6 27 4.2 0.1 4.1 1 1 4 5 5 5 0 Foie gras liver health family 1 UCR_UQCRX_QCR9 PF05365.12 OEU07773.1 - 0.54 10.2 6.5 19 5.3 0.0 4.6 5 0 0 5 5 5 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like LRR_8 PF13855.6 OEU07774.1 - 3.1e-12 46.1 6.3 1.8e-07 30.8 0.2 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OEU07774.1 - 3.7e-06 27.2 7.0 0.059 13.8 0.5 4.2 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU07774.1 - 4.3e-06 26.5 2.3 4.5 8.2 0.1 5.7 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU07774.1 - 0.014 15.4 1.2 21 5.5 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat GST_N_3 PF13417.6 OEU07775.1 - 2.7e-11 43.7 0.0 5.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU07775.1 - 7.7e-10 39.0 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU07775.1 - 7.2e-07 29.4 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU07775.1 - 0.00065 19.7 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3450 PF11932.8 OEU07775.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GST_C PF00043.25 OEU07775.1 - 0.031 14.5 0.1 0.068 13.4 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OEU07775.1 - 0.097 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin DUF1524 PF07510.11 OEU07776.1 - 1.1e-18 67.5 6.5 1.1e-18 67.5 6.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1524) DUF262 PF03235.14 OEU07776.1 - 3.7e-14 53.4 1.7 3.7e-14 53.4 1.7 2.2 2 1 0 2 2 2 1 Protein of unknown function DUF262 Mucin PF01456.17 OEU07778.1 - 0.067 13.2 23.0 0.11 12.5 7.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Eaf7 PF07904.13 OEU07780.1 - 0.034 14.5 0.5 0.034 14.5 0.5 3.0 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Cas_Csx9 PF09658.10 OEU07780.1 - 0.16 11.2 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) PepSY_TM PF03929.16 OEU07780.1 - 1.1 8.8 3.8 2 8.0 0.9 2.2 2 0 0 2 2 2 0 PepSY-associated TM region Androgen_recep PF02166.16 OEU07780.1 - 1.4 7.7 31.0 2.8 6.7 2.6 2.5 2 0 0 2 2 2 0 Androgen receptor DUF4746 PF15928.5 OEU07780.1 - 2.6 7.4 7.6 0.1 12.0 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF3494 PF11999.8 OEU07782.1 - 4.2e-61 206.2 13.6 4.7e-61 206.1 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) HP_OMP_2 PF02521.14 OEU07782.1 - 0.15 10.9 0.3 0.22 10.4 0.3 1.2 1 0 0 1 1 1 0 Putative outer membrane protein Lin0512_fam PF09585.10 OEU07783.1 - 0.0027 17.7 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) HTH_26 PF13443.6 OEU07783.1 - 0.11 12.9 0.0 0.58 10.6 0.0 2.0 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Atg14 PF10186.9 OEU07786.1 - 0.0083 15.2 1.8 0.012 14.7 1.8 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 OEU07786.1 - 0.0097 14.5 6.2 0.011 14.3 6.2 1.1 1 0 0 1 1 1 1 Macoilin family YabA PF06156.13 OEU07786.1 - 0.05 14.2 8.8 0.17 12.6 8.8 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Band_3_cyto PF07565.13 OEU07786.1 - 0.068 13.0 0.6 0.092 12.5 0.0 1.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FlaC_arch PF05377.11 OEU07786.1 - 0.2 12.1 5.8 3.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 OEU07786.1 - 0.23 11.4 5.9 0.22 11.5 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF724 PF05266.14 OEU07786.1 - 2.5 7.9 10.2 3.7 7.3 7.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 OEU07786.1 - 3.1 5.6 7.6 5.1 4.9 7.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family I_LWEQ PF01608.17 OEU07786.1 - 3.5 7.8 8.5 2.4 8.4 5.3 2.3 1 1 1 2 2 2 0 I/LWEQ domain APG6_N PF17675.1 OEU07786.1 - 7.5 7.1 14.3 9 6.8 10.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PGPGW PF09656.10 OEU07787.1 - 0.14 11.7 1.1 0.31 10.6 1.1 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Chloroa_b-bind PF00504.21 OEU07788.1 - 3.1e-33 115.6 0.0 5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RmuC PF02646.16 OEU07789.1 - 1.8e-25 89.7 0.5 2.6e-25 89.2 0.5 1.2 1 0 0 1 1 1 1 RmuC family FlbD PF06289.11 OEU07789.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins DUF999 PF06198.11 OEU07789.1 - 0.12 12.4 2.4 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF999) HALZ PF02183.18 OEU07789.1 - 0.16 12.2 2.8 1 9.7 0.1 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4010 PF13194.6 OEU07791.1 - 1.3 8.6 6.8 0.068 12.8 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Gly_rich PF12810.7 OEU07792.1 - 0.021 14.7 9.3 0.091 12.7 9.3 1.8 1 1 0 1 1 1 0 Glycine rich protein DUF1754 PF08555.10 OEU07792.1 - 0.33 11.8 9.7 0.96 10.3 9.7 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FAM60A PF15396.6 OEU07792.1 - 0.98 9.4 4.8 1.6 8.7 4.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Pneumo_att_G PF05539.11 OEU07792.1 - 6.8 6.2 8.6 10 5.6 8.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Sulfatase PF00884.23 OEU07793.1 - 9.6e-36 123.7 3.7 4.6e-34 118.2 3.7 2.9 1 1 0 1 1 1 1 Sulfatase DUF285 PF03382.14 OEU07793.1 - 8.1e-11 41.7 5.6 8.1e-11 41.7 5.6 4.1 2 1 2 4 4 4 2 Mycoplasma protein of unknown function, DUF285 LRRNT_2 PF08263.12 OEU07793.1 - 0.45 10.9 5.0 1.9 8.9 0.2 3.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DM13 PF10517.9 OEU07793.1 - 1.8 9.2 5.1 0.44 11.2 0.1 2.7 3 0 0 3 3 3 0 Electron transfer DM13 Hamartin PF04388.12 OEU07793.1 - 8.3 4.9 20.0 0.17 10.6 5.9 2.4 2 0 0 2 2 2 0 Hamartin protein HMG_box PF00505.19 OEU07794.1 - 1.4e-08 35.0 0.1 1.4e-08 35.0 0.1 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU07794.1 - 0.017 15.7 0.0 0.017 15.7 0.0 1.0 1 0 0 1 1 1 0 HMG-box domain Tnp_22_trimer PF17489.2 OEU07796.1 - 0.34 10.9 13.5 0.43 10.6 1.4 3.0 3 1 0 3 3 3 0 L1 transposable element trimerization domain YacG PF03884.14 OEU07796.1 - 0.42 10.4 16.1 0.6 9.9 0.8 3.9 3 1 0 3 3 3 0 DNA gyrase inhibitor YacG Phage_terminase PF10668.9 OEU07796.1 - 1.8 8.7 5.5 5.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Phage terminase small subunit DUF285 PF03382.14 OEU07797.1 - 1.1e-216 706.3 128.6 1.3e-32 112.1 6.7 6.4 1 1 7 8 8 8 8 Mycoplasma protein of unknown function, DUF285 2OG-Fe_Oxy_2 PF10014.9 OEU07798.1 - 5.6e-14 52.4 0.0 7.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase Mg_chelatase PF01078.21 OEU07798.1 - 0.051 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Chloroa_b-bind PF00504.21 OEU07801.1 - 9.5e-33 114.0 0.0 1.2e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATG16 PF08614.11 OEU07803.1 - 0.0047 17.2 7.2 0.0047 17.2 7.2 3.4 2 2 0 3 3 3 1 Autophagy protein 16 (ATG16) HP0268 PF18618.1 OEU07803.1 - 0.076 13.4 0.6 0.076 13.4 0.6 2.3 2 0 0 2 2 2 0 HP0268 APG6_N PF17675.1 OEU07803.1 - 0.58 10.7 15.7 0.34 11.4 4.5 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Beta-lactamase PF00144.24 OEU07804.1 - 1.1e-05 24.9 0.0 0.00051 19.4 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase Germane PF10646.9 OEU07804.1 - 0.022 15.5 0.0 0.058 14.2 0.0 1.7 2 0 0 2 2 2 0 Sporulation and spore germination Vfa1 PF08432.10 OEU07805.1 - 0.21 11.9 1.3 0.28 11.5 1.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 OEU07805.1 - 0.72 9.2 8.6 0.8 9.1 8.6 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 OEU07805.1 - 1.3 6.7 3.8 1.5 6.5 3.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 OEU07805.1 - 4 5.5 10.1 4.3 5.4 10.1 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 OEU07805.1 - 4.1 5.9 12.9 4.8 5.7 12.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3327 PF11806.8 OEU07806.1 - 0.068 13.9 1.1 0.099 13.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) DUF805 PF05656.14 OEU07806.1 - 0.2 12.1 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Ribophorin_II PF05817.14 OEU07806.1 - 0.27 9.8 5.4 0.31 9.5 5.4 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II AAA_11 PF13086.6 OEU07806.1 - 0.65 9.7 11.2 0.81 9.4 11.2 1.1 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 OEU07806.1 - 0.95 8.6 2.3 1.1 8.5 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Atg14 PF10186.9 OEU07806.1 - 2.2 7.3 16.3 3.9 6.5 16.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF913 PF06025.12 OEU07806.1 - 5 6.0 8.9 6.8 5.6 8.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 OEU07806.1 - 6 5.3 16.2 7 5.1 16.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4746 PF15928.5 OEU07806.1 - 6.5 6.1 19.1 7.7 5.8 19.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Rtf2 PF04641.12 OEU07806.1 - 8 5.7 17.8 9.9 5.4 17.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Glyco_transf_41 PF13844.6 OEU07809.1 - 8.6e-55 186.0 0.0 3.2e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Glycosyl transferase family 41 NPL4 PF05021.15 OEU07810.1 - 6.5e-17 61.8 0.5 2.1e-10 40.5 0.5 3.1 1 1 1 2 2 2 2 NPL4 family GshA PF08886.11 OEU07810.1 - 0.078 11.5 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase CDP-OH_P_transf PF01066.21 OEU07811.1 - 4e-14 53.1 1.5 4e-14 53.1 1.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2373 PF10180.9 OEU07812.1 - 1.1e-19 70.0 1.2 2.4e-19 68.9 1.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) RR_TM4-6 PF06459.12 OEU07812.1 - 8.2 6.2 28.8 1.2 8.9 9.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCT PF06203.14 OEU07813.1 - 1.1e-16 60.6 13.2 2.5e-16 59.4 13.2 1.7 1 0 0 1 1 1 1 CCT motif DUF523 PF04463.12 OEU07813.1 - 0.12 12.5 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF523) DUF2407 PF10302.9 OEU07813.1 - 0.56 10.8 5.3 3.3 8.3 0.9 2.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain GTP_EFTU PF00009.27 OEU07814.1 - 3.3e-43 147.5 0.1 5e-43 146.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OEU07814.1 - 1.7e-33 115.2 0.9 2.9e-33 114.5 0.1 1.9 2 0 0 2 2 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OEU07814.1 - 3.8e-09 36.8 0.1 1.2e-08 35.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU07814.1 - 1.5e-08 34.7 1.1 4.3e-07 30.0 1.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OEU07814.1 - 0.00051 20.1 0.3 0.16 12.0 0.4 2.5 2 0 0 2 2 2 1 Dynamin family SRPRB PF09439.10 OEU07814.1 - 0.00062 19.3 1.3 0.0024 17.3 0.4 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OEU07814.1 - 0.00077 18.7 1.2 0.55 9.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU_D4 PF14578.6 OEU07814.1 - 0.0013 18.6 0.2 0.0038 17.1 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.12 OEU07814.1 - 0.041 13.2 0.3 0.22 10.9 0.3 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OEU07814.1 - 0.059 13.1 2.3 0.48 10.2 0.9 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OEU07814.1 - 0.18 11.1 2.9 0.48 9.7 2.9 1.6 1 1 0 1 1 1 0 Septin Roc PF08477.13 OEU07814.1 - 0.61 10.3 4.1 1.4 9.1 1.5 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SLX9 PF15341.6 OEU07815.1 - 2e-14 54.1 11.5 2e-14 54.1 11.5 3.2 2 1 1 3 3 3 1 Ribosome biogenesis protein SLX9 dCMP_cyt_deam_1 PF00383.23 OEU07816.1 - 1.7e-18 66.3 1.3 8.2e-17 60.9 1.3 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OEU07816.1 - 5.6e-11 42.3 5.3 4.1e-10 39.6 5.3 2.3 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OEU07816.1 - 0.00025 21.1 0.2 0.0006 19.9 0.2 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase Ycf1 PF05758.12 OEU07817.1 - 0.081 10.8 0.2 0.11 10.3 0.2 1.2 1 0 0 1 1 1 0 Ycf1 DUF1744 PF08490.12 OEU07817.1 - 0.16 10.5 3.4 0.26 9.8 2.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1744) Mito_carr PF00153.27 OEU07818.1 - 5.9e-55 183.2 3.6 1.9e-20 72.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.27 OEU07819.1 - 5.5e-05 22.8 0.0 0.00022 20.8 0.0 2.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU07819.1 - 0.0005 19.7 0.2 0.0012 18.4 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU07819.1 - 0.055 14.2 0.6 0.29 11.9 0.6 2.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase adh_short PF00106.25 OEU07820.1 - 1.1e-22 80.5 0.4 1.3e-22 80.3 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU07820.1 - 3.4e-13 49.7 0.3 3.8e-13 49.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU07820.1 - 2.5e-06 27.5 0.3 2.9e-06 27.3 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OEU07820.1 - 0.0015 18.5 0.1 0.058 13.3 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Baculo_p24 PF05073.12 OEU07821.1 - 0.02 14.7 0.0 0.061 13.1 0.0 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Met_asp_mut_E PF06368.11 OEU07821.1 - 0.12 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) CBF PF03914.17 OEU07822.1 - 6.4e-29 101.2 0.8 6.4e-29 101.2 0.8 2.4 3 0 0 3 3 3 1 CBF/Mak21 family YL1 PF05764.13 OEU07822.1 - 0.00022 21.4 11.4 0.00022 21.4 11.4 1.6 2 0 0 2 2 2 1 YL1 nuclear protein Tim54 PF11711.8 OEU07822.1 - 0.0023 16.8 0.2 0.0038 16.1 0.2 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sigma70_ner PF04546.13 OEU07822.1 - 0.0027 17.6 4.1 0.0051 16.7 4.1 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region Nop14 PF04147.12 OEU07822.1 - 0.0036 15.6 13.0 0.0053 15.1 13.0 1.2 1 0 0 1 1 1 1 Nop14-like family RRN3 PF05327.11 OEU07822.1 - 0.015 13.9 5.3 0.021 13.4 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 OEU07822.1 - 0.028 12.7 12.7 0.041 12.2 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 OEU07822.1 - 0.09 12.1 10.9 0.16 11.4 10.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Med13_C PF06333.12 OEU07822.1 - 0.09 12.0 0.5 0.14 11.4 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Spt5_N PF11942.8 OEU07822.1 - 0.15 13.1 16.9 0.3 12.1 16.9 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.12 OEU07822.1 - 0.16 11.7 16.6 0.29 10.8 16.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 OEU07822.1 - 0.24 10.8 16.2 0.42 10.0 16.2 1.3 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.6 OEU07822.1 - 0.44 10.3 5.7 0.99 9.1 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 OEU07822.1 - 0.48 8.5 22.1 0.78 7.8 22.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 OEU07822.1 - 0.79 9.0 19.4 1.3 8.3 19.4 1.3 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 OEU07822.1 - 2.2 6.3 10.5 2.6 6.0 10.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.12 OEU07822.1 - 2.3 8.2 9.4 4.1 7.3 9.4 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SURF2 PF05477.11 OEU07822.1 - 2.7 7.6 9.8 1.1 9.0 7.0 1.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) RXT2_N PF08595.11 OEU07822.1 - 2.8 7.9 9.9 5.5 7.0 9.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Apt1 PF10351.9 OEU07822.1 - 2.8 6.7 8.7 4.2 6.1 8.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM176 PF14851.6 OEU07822.1 - 3.3 7.4 9.1 8.2 6.1 9.1 1.7 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 OEU07822.1 - 5.8 5.9 26.2 8.8 5.4 26.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 OEU07822.1 - 6.6 7.0 12.5 14 5.9 12.5 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated VTC PF09359.10 OEU07823.1 - 2.3e-57 194.5 0.0 4.7e-57 193.5 0.0 1.5 1 0 0 1 1 1 1 VTC domain Scramblase PF03803.15 OEU07825.1 - 1.8e-18 66.7 0.6 5.8e-08 32.3 0.1 2.4 2 1 0 2 2 2 2 Scramblase THUMP PF02926.17 OEU07826.1 - 3.7e-19 69.3 0.8 4.8e-19 68.9 0.8 1.1 1 0 0 1 1 1 1 THUMP domain Ribosomal_L3 PF00297.22 OEU07827.1 - 8.6e-18 64.4 1.4 6e-16 58.4 0.9 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 DUF285 PF03382.14 OEU07828.1 - 6.5e-53 177.6 20.3 2.2e-31 108.1 6.6 2.7 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 BssS PF13991.6 OEU07828.1 - 0.11 12.6 1.7 5 7.3 0.0 3.2 2 1 2 4 4 4 0 BssS protein family DNA_pol_B_N PF18094.1 OEU07829.1 - 0.13 12.8 0.4 0.17 12.4 0.3 1.4 1 1 0 1 1 1 0 DNA polymerase beta N-terminal domain DUF179 PF02622.15 OEU07832.1 - 2.1e-18 66.8 0.7 3.2e-08 33.7 0.5 3.7 2 1 0 2 2 2 2 Uncharacterized ACR, COG1678 DHR-2 PF06920.13 OEU07833.1 - 9.2e-06 24.6 0.0 3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Dock homology region 2 DnaJ PF00226.31 OEU07834.1 - 9.6e-11 41.7 2.3 9.6e-11 41.7 2.3 1.8 2 0 0 2 2 2 1 DnaJ domain DUF5353 PF17304.2 OEU07834.1 - 0.29 10.9 1.2 0.9 9.3 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5353) ShK PF01549.24 OEU07834.1 - 0.66 10.6 6.1 1.7 9.2 6.1 1.8 1 1 0 1 1 1 0 ShK domain-like Spore_YhcN_YlaJ PF09580.10 OEU07834.1 - 2.1 8.4 8.9 4.7 7.3 8.9 1.6 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AF-4 PF05110.13 OEU07834.1 - 6.5 4.7 15.2 8.4 4.3 15.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cellulase PF00150.18 OEU07835.1 - 3e-19 69.6 3.2 4e-19 69.1 3.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DDHD PF02862.17 OEU07837.1 - 4.5e-32 112.0 0.0 8.5e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.7 OEU07837.1 - 0.094 13.3 0.0 0.29 11.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family AIM24 PF01987.17 OEU07839.1 - 2.4e-41 141.8 0.3 2.7e-41 141.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SHMT PF00464.19 OEU07841.1 - 3.7e-175 582.3 0.0 4.4e-175 582.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OEU07841.1 - 8.3e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase dCMP_cyt_deam_1 PF00383.23 OEU07842.1 - 3.4e-13 49.3 0.0 7.6e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CRS1_YhbY PF01985.21 OEU07842.1 - 4.3e-05 23.6 0.2 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 CRS1 / YhbY (CRM) domain Inv-AAD PF18785.1 OEU07842.1 - 6.8e-05 22.7 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 2 Invertebrate-AID/APOBEC-deaminase MafB19-deam PF14437.6 OEU07842.1 - 0.043 13.6 0.5 0.95 9.2 0.2 2.8 2 2 0 2 2 2 0 MafB19-like deaminase MlaA PF04333.13 OEU07842.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 MlaA lipoprotein PseudoU_synth_2 PF00849.22 OEU07843.1 - 2e-24 86.5 0.0 2.9e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase MGC-24 PF05283.11 OEU07844.1 - 0.013 16.0 3.1 0.013 16.0 3.1 3.6 4 1 0 4 4 4 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3612 PF12268.8 OEU07844.1 - 0.097 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) MRI PF15325.6 OEU07844.1 - 2.4 9.3 14.2 4.4 8.4 2.0 3.2 2 0 0 2 2 2 0 Modulator of retrovirus infection PseudoU_synth_2 PF00849.22 OEU07845.1 - 9.2e-25 87.6 0.0 1.3e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase ParA PF10609.9 OEU07846.1 - 2.6e-80 269.4 0.1 4.6e-80 268.6 0.1 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 OEU07846.1 - 2.6e-14 53.6 0.0 8.6e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) FeS_assembly_P PF01883.19 OEU07846.1 - 7.1e-13 48.5 0.2 1.8e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 OEU07846.1 - 1.6e-10 41.1 0.0 2.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OEU07846.1 - 2.3e-10 40.7 0.4 2.1e-08 34.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 OEU07846.1 - 3.9e-07 29.6 0.0 7.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 OEU07846.1 - 6.5e-05 22.5 0.1 0.017 14.6 0.1 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OEU07846.1 - 0.00062 19.3 0.0 0.033 13.6 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 OEU07846.1 - 0.0019 17.4 3.4 0.15 11.2 0.7 2.9 2 1 1 3 3 3 2 Anion-transporting ATPase VirC1 PF07015.11 OEU07846.1 - 0.0021 17.4 0.1 0.0048 16.2 0.1 1.5 1 0 0 1 1 1 1 VirC1 protein FTHFS PF01268.19 OEU07846.1 - 0.037 12.2 0.1 0.057 11.6 0.1 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Peptidase_S51 PF03575.17 OEU07847.1 - 1.1e-09 38.2 0.0 5.7e-09 35.9 0.0 2.0 2 1 0 2 2 2 1 Peptidase family S51 YCII PF03795.14 OEU07848.1 - 2.3e-05 24.7 0.0 0.00086 19.7 0.0 2.4 2 0 0 2 2 2 1 YCII-related domain G_glu_transpept PF01019.21 OEU07849.1 - 1.6e-124 416.5 0.0 3.1e-107 359.5 0.0 3.1 2 1 0 2 2 2 2 Gamma-glutamyltranspeptidase Macoilin PF09726.9 OEU07851.1 - 0.095 11.2 1.6 0.11 11.0 1.6 1.1 1 0 0 1 1 1 0 Macoilin family Lin0512_fam PF09585.10 OEU07852.1 - 4.1e-26 91.2 0.0 4.8e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) FRG2 PF15315.6 OEU07853.1 - 0.025 14.8 2.2 0.027 14.7 2.2 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 YccV-like PF08755.11 OEU07853.1 - 0.045 14.3 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like TSC22 PF01166.18 OEU07853.1 - 5.6 7.4 9.2 23 5.4 9.2 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF616 PF04765.13 OEU07854.1 - 5.3e-05 22.6 0.2 0.044 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF616) Pkinase PF00069.25 OEU07855.1 - 2.3e-66 223.9 0.0 2.7e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU07855.1 - 5e-35 121.0 0.0 6.4e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU07855.1 - 3e-06 26.8 0.0 2.2e-05 23.9 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OEU07855.1 - 5.5e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OEU07855.1 - 0.00054 19.6 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OEU07855.1 - 0.0017 18.3 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU07855.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHR-2 PF06920.13 OEU07856.1 - 4.3e-20 71.9 0.0 9.2e-10 37.8 0.0 3.3 3 0 0 3 3 3 3 Dock homology region 2 DOCK-C2 PF14429.6 OEU07856.1 - 2.7e-09 37.1 0.0 7.4e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SNAP PF14938.6 OEU07856.1 - 1.5 8.1 3.5 0.8 9.1 0.2 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Fer4_NifH PF00142.18 OEU07857.1 - 0.018 14.5 0.3 0.03 13.7 0.3 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Glyco_transf_92 PF01697.27 OEU07858.1 - 1.2e-06 28.4 0.9 1.6e-05 24.7 0.9 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU07858.1 - 2.1e-05 25.0 2.2 4.7e-05 23.8 2.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Voldacs PF03517.13 OEU07859.1 - 0.00086 19.4 0.5 0.003 17.7 0.5 1.8 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling CENP-B_dimeris PF09026.10 OEU07859.1 - 0.032 14.6 0.5 0.47 10.9 0.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LRR_6 PF13516.6 OEU07860.1 - 3.9e-25 85.7 13.3 8e-05 22.4 0.0 8.6 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 OEU07860.1 - 8.9e-09 34.7 0.7 20 6.2 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 OEU07860.1 - 5.5e-05 23.5 4.4 0.051 14.0 0.0 5.0 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU07860.1 - 0.035 13.9 2.2 14 5.6 0.1 4.5 4 1 0 4 4 4 0 Leucine rich repeat TFA2_Winged_2 PF18121.1 OEU07861.1 - 9.1e-08 31.7 0.0 3.1e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OEU07861.1 - 0.00019 21.6 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain HSM3_N PF18795.1 OEU07861.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain SYS1 PF09801.9 OEU07862.1 - 5.4e-38 130.4 8.8 6e-38 130.2 8.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network VIT1 PF01988.19 OEU07862.1 - 0.17 11.7 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 VIT family AFG1_ATPase PF03969.16 OEU07863.1 - 0.047 12.6 0.2 0.093 11.6 0.2 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Cadherin_C_2 PF16492.5 OEU07863.1 - 0.11 13.3 0.1 0.42 11.4 0.0 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal adh_short PF00106.25 OEU07864.1 - 1e-42 145.8 0.5 1.3e-42 145.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU07864.1 - 7.5e-28 97.7 0.1 1.4e-27 96.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU07864.1 - 7.5e-09 35.8 0.3 1.3e-08 35.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU07864.1 - 8.4e-08 32.0 0.4 6.5e-06 25.8 0.1 2.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU07864.1 - 0.00012 21.6 0.2 0.00016 21.2 0.2 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OEU07864.1 - 0.00022 20.5 0.6 0.0063 15.7 0.6 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OEU07864.1 - 0.00025 20.3 0.3 0.00037 19.7 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 OEU07864.1 - 0.00033 20.6 0.3 0.0012 18.7 0.1 1.9 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OEU07864.1 - 0.00051 20.6 0.2 0.0016 19.0 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 OEU07864.1 - 0.012 15.9 0.6 0.022 15.1 0.6 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OEU07864.1 - 0.015 15.2 0.5 0.28 11.1 0.5 2.6 1 1 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 OEU07864.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TraG-D_C PF12696.7 OEU07864.1 - 0.048 13.7 0.1 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG NAD_Gly3P_dh_N PF01210.23 OEU07864.1 - 0.049 13.6 0.1 0.079 12.9 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fer2 PF00111.27 OEU07865.1 - 0.00036 20.4 0.3 0.0012 18.8 0.3 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain His_Phos_2 PF00328.22 OEU07867.1 - 4.6e-14 52.6 0.0 1.6e-08 34.3 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) E3_UFM1_ligase PF09743.9 OEU07868.1 - 3.6e-18 66.2 4.1 1.3e-17 64.3 0.4 3.0 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 YmgB PF10798.8 OEU07868.1 - 0.006 16.4 1.1 0.017 15.0 0.1 2.3 2 0 0 2 2 2 1 Biofilm development protein YmgB/AriR Sporozoite_P67 PF05642.11 OEU07868.1 - 0.016 13.3 6.5 0.026 12.6 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PGA2 PF07543.12 OEU07868.1 - 0.3 11.1 6.1 0.88 9.6 6.1 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 RP-C_C PF11800.8 OEU07868.1 - 0.36 10.9 1.4 1.1 9.3 1.4 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region RPN2_C PF18004.1 OEU07868.1 - 0.46 10.4 6.2 1.1 9.2 6.2 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 OEU07868.1 - 1.8 9.0 8.8 8.7 6.8 8.8 2.2 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mago_nashi PF02792.14 OEU07869.1 - 5.4e-59 198.4 0.0 6.3e-59 198.2 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein ABC2_membrane PF01061.24 OEU07870.1 - 1.7e-42 145.2 16.6 2.5e-42 144.7 16.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OEU07870.1 - 9.9e-22 77.9 0.0 1.5e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU07870.1 - 6.1e-07 29.5 0.1 0.0084 16.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU07870.1 - 1.5e-06 27.8 0.0 2.2e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 OEU07870.1 - 3.7e-05 23.0 14.2 6.1e-05 22.3 14.2 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OEU07870.1 - 0.00047 20.1 0.1 0.00095 19.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OEU07870.1 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OEU07870.1 - 0.0026 18.3 0.0 0.0049 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 OEU07870.1 - 0.0085 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 OEU07870.1 - 0.014 15.1 0.3 0.039 13.7 0.1 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU07870.1 - 0.024 14.9 0.1 0.063 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OEU07870.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 OEU07870.1 - 0.032 13.2 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CLP1_P PF16575.5 OEU07870.1 - 0.052 13.3 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 OEU07870.1 - 0.055 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OEU07870.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OEU07870.1 - 0.11 12.4 0.5 0.74 9.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OEU07870.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OEU07870.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OEU07870.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU07870.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU07870.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OEU07870.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OEU07870.1 - 0.23 10.7 0.0 0.56 9.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Radical_SAM PF04055.21 OEU07871.1 - 6e-12 46.3 0.6 1.1e-05 25.9 0.0 2.4 3 0 0 3 3 3 2 Radical SAM superfamily UreE_N PF02814.15 OEU07871.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain RNA_pol_Rpb4 PF03874.16 OEU07872.1 - 5.6e-15 55.7 4.9 5.6e-15 55.7 4.9 2.0 1 1 1 2 2 2 1 RNA polymerase Rpb4 TraU PF06834.11 OEU07872.1 - 0.07 12.4 0.1 0.088 12.1 0.0 1.3 1 1 0 1 1 1 0 TraU protein DUF4734 PF15881.5 OEU07872.1 - 0.49 10.6 3.6 0.44 10.8 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4734) Xpo1 PF08389.12 OEU07872.1 - 2.4 8.2 5.9 7.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Fer2 PF00111.27 OEU07873.1 - 0.014 15.4 2.3 0.041 13.8 2.3 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF4205 PF13898.6 OEU07874.1 - 0.00011 21.2 3.9 0.012 14.6 0.2 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF4205) DUF4336 PF14234.6 OEU07875.1 - 8.1e-98 327.5 1.1 1.1e-97 327.1 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) DUF730 PF05325.11 OEU07876.1 - 0.01 15.9 0.4 0.021 14.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF730) DUF1664 PF07889.12 OEU07876.1 - 0.12 12.5 0.5 0.25 11.4 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HSF_DNA-bind PF00447.17 OEU07877.1 - 1.4e-25 89.8 1.3 1.5e-25 89.6 1.3 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Siva PF05458.12 OEU07878.1 - 0.0033 17.1 14.3 0.0033 17.1 14.3 1.8 2 0 0 2 2 2 1 Cd27 binding protein (Siva) DUF4116 PF13475.6 OEU07880.1 - 4.8e-15 55.0 3.9 0.00052 19.7 0.0 7.3 6 3 2 8 8 8 5 Domain of unknown function (DUF4116) Hydrolase_4 PF12146.8 OEU07881.1 - 4e-11 42.6 0.1 2.9e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU07881.1 - 1.6e-06 28.0 0.1 0.0015 18.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU07881.1 - 4.2e-06 27.5 0.0 0.00017 22.3 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 OEU07881.1 - 2.2e-05 23.3 0.0 0.0011 17.8 0.0 2.3 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 OEU07881.1 - 7e-05 22.9 0.0 0.0042 17.0 0.0 2.4 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OEU07881.1 - 7e-05 22.5 0.0 0.0019 17.8 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OEU07881.1 - 0.00011 22.2 0.0 0.00033 20.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 OEU07881.1 - 0.0046 16.6 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S10 PF00450.22 OEU07881.1 - 0.012 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Peptidase_S9 PF00326.21 OEU07881.1 - 0.026 14.0 0.0 0.17 11.3 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 OEU07881.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 OEU07881.1 - 0.068 13.0 0.7 3.8 7.2 0.0 2.7 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 OEU07881.1 - 0.097 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF829 PF05705.14 OEU07881.1 - 0.13 12.2 0.0 11 5.8 0.0 2.2 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) COesterase PF00135.28 OEU07881.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family UDPG_MGDP_dh_N PF03721.14 OEU07882.1 - 4.7e-57 192.6 0.2 7.7e-57 191.9 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OEU07882.1 - 3.1e-32 110.6 0.0 6.8e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OEU07882.1 - 8.4e-32 109.7 0.0 1e-30 106.2 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_7 PF13241.6 OEU07882.1 - 0.00068 20.0 0.0 0.99 9.9 0.0 2.9 2 1 1 3 3 3 2 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OEU07882.1 - 0.12 12.6 0.6 0.47 10.7 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Gly-zipper_YMGG PF13441.6 OEU07883.1 - 0.0055 16.4 3.3 0.0055 16.4 3.3 1.8 2 0 0 2 2 2 1 YMGG-like Gly-zipper DUF456 PF04306.13 OEU07883.1 - 0.0058 16.9 0.8 0.0094 16.2 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) GFA PF04828.14 OEU07884.1 - 3.4e-16 59.4 22.3 5.2e-09 36.3 5.2 3.2 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme EF-hand_1 PF00036.32 OEU07885.1 - 3.9e-11 41.7 1.0 0.00011 21.5 0.0 2.9 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 OEU07885.1 - 4.9e-10 38.4 2.7 1.4e-05 24.4 0.0 3.1 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU07885.1 - 2.4e-08 33.3 0.2 0.0018 18.0 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU07885.1 - 3.8e-07 30.5 0.3 0.0082 16.6 0.0 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OEU07885.1 - 8e-05 22.4 0.5 0.092 12.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 OEU07885.1 - 0.0019 18.4 0.3 2.7 8.3 0.0 2.7 2 0 0 2 2 2 2 Dockerin type I domain WAP PF00095.21 OEU07885.1 - 0.004 17.5 7.4 0.0088 16.4 7.4 1.6 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' SPARC_Ca_bdg PF10591.9 OEU07885.1 - 0.0051 17.1 1.4 0.16 12.3 0.0 3.0 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5421 PF17458.2 OEU07885.1 - 0.91 8.9 10.2 0.97 8.8 1.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Aminotran_1_2 PF00155.21 OEU07886.1 - 1.3e-39 136.5 0.0 1.6e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OEU07886.1 - 5.6e-05 21.8 0.0 0.0001 21.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OEU07886.1 - 0.052 12.5 0.1 2.8 6.8 0.0 2.9 2 2 0 2 2 2 0 Aminotransferase class-V SMC_N PF02463.19 OEU07887.1 - 1.1e-60 204.8 50.8 5.8e-60 202.5 50.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OEU07887.1 - 1.2e-24 86.8 0.3 1.6e-23 83.2 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OEU07887.1 - 1.4e-08 34.9 20.2 2.8e-06 27.3 0.5 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OEU07887.1 - 8e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3450 PF11932.8 OEU07887.1 - 0.00094 18.6 3.7 0.00094 18.6 3.7 7.7 3 2 5 8 8 8 2 Protein of unknown function (DUF3450) ABC_tran PF00005.27 OEU07887.1 - 0.44 11.0 0.0 0.44 11.0 0.0 6.4 3 2 1 4 4 4 0 ABC transporter DUF4834 PF16118.5 OEU07888.1 - 0.064 14.2 0.0 0.064 14.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Orn_Arg_deC_N PF02784.16 OEU07889.1 - 6.5e-22 78.1 0.0 1.7e-19 70.2 0.0 3.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OEU07889.1 - 1.2e-05 25.5 0.1 4.6e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain E1_dh PF00676.20 OEU07889.1 - 0.0086 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component zf-H2C2_2 PF13465.6 OEU07889.1 - 1.4 9.5 3.5 3.6 8.2 3.5 1.7 1 0 0 1 1 1 0 Zinc-finger double domain BCOR PF15808.5 OEU07890.1 - 0.19 11.9 6.3 0.046 14.0 1.2 1.9 1 1 1 2 2 2 0 BCL-6 co-repressor, non-ankyrin-repeat region Peptidase_M50 PF02163.22 OEU07891.1 - 1.4e-07 31.1 1.9 0.0022 17.3 0.5 2.3 2 0 0 2 2 2 2 Peptidase family M50 dsDNA_bind PF01984.20 OEU07893.1 - 1.9e-25 89.3 1.6 2.4e-25 89.0 1.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF1779 PF08680.10 OEU07893.1 - 0.05 13.8 0.4 0.064 13.4 0.4 1.1 1 0 0 1 1 1 0 TATA-box binding K_channel_TID PF07941.11 OEU07893.1 - 8.9 6.9 11.7 0.5 10.8 6.1 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain AAA_11 PF13086.6 OEU07894.1 - 3.1e-69 233.7 0.0 3.1e-69 233.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 OEU07894.1 - 1.6e-52 178.1 0.0 3.3e-52 177.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OEU07894.1 - 4.8e-08 33.0 0.0 0.0094 15.7 0.0 3.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OEU07894.1 - 9e-08 32.1 0.1 0.0039 16.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OEU07894.1 - 3.1e-06 27.6 0.5 9.7e-05 22.7 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU07894.1 - 4.1e-06 27.1 0.0 0.0003 21.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain WW PF00397.26 OEU07894.1 - 0.0001 22.3 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 WW domain AAA PF00004.29 OEU07894.1 - 0.00084 19.8 0.0 0.025 15.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OEU07894.1 - 0.0027 17.0 0.0 0.083 12.1 0.0 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OEU07894.1 - 0.0034 17.8 0.0 0.055 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 OEU07894.1 - 0.005 16.6 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 OEU07894.1 - 0.0065 16.5 2.3 0.86 9.6 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 OEU07894.1 - 0.11 11.9 15.5 0.19 11.2 15.5 1.3 1 0 0 1 1 1 0 SDA1 AAA_29 PF13555.6 OEU07894.1 - 0.12 12.1 0.1 0.56 10.0 0.1 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OEU07894.1 - 0.13 12.1 0.2 1 9.3 0.0 2.4 2 0 0 2 2 2 0 NTPase GCIP PF13324.6 OEU07894.1 - 2.3 7.8 6.7 1.6 8.3 4.6 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Atg14 PF10186.9 OEU07894.1 - 5.6 5.9 6.6 0.26 10.3 0.7 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DnaJ PF00226.31 OEU07895.1 - 9.5e-25 86.5 1.5 1e-24 86.4 1.5 1.0 1 0 0 1 1 1 1 DnaJ domain E2F_TDP PF02319.20 OEU07895.1 - 0.12 12.5 0.1 0.39 10.8 0.0 1.8 1 1 1 2 2 2 0 E2F/DP family winged-helix DNA-binding domain LAP1C PF05609.12 OEU07896.1 - 0.049 12.7 7.5 0.06 12.4 7.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cupin_8 PF13621.6 OEU07897.1 - 6e-15 55.6 3.2 9.7e-15 55.0 3.2 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU07897.1 - 9.5e-08 31.9 1.3 1.2e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 OEU07897.1 - 0.0039 16.9 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OEU07897.1 - 0.0046 16.6 0.0 0.0097 15.5 0.0 1.6 1 0 0 1 1 1 1 Cupin JmjC PF02373.22 OEU07897.1 - 0.0074 16.7 5.1 0.0084 16.5 0.3 2.9 3 1 0 3 3 3 1 JmjC domain, hydroxylase HSF_DNA-bind PF00447.17 OEU07898.1 - 3.1e-30 104.7 1.5 6.8e-30 103.5 1.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF812 PF05667.11 OEU07898.1 - 3.2e-05 23.0 1.5 3.2e-05 23.0 1.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Pox_A_type_inc PF04508.12 OEU07898.1 - 0.0091 15.8 0.1 0.029 14.2 0.1 1.9 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat DUF4988 PF16378.5 OEU07898.1 - 0.028 14.1 0.3 0.073 12.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function Syntaxin-6_N PF09177.11 OEU07898.1 - 0.038 14.6 5.9 0.11 13.1 1.1 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FTA4 PF13093.6 OEU07898.1 - 0.11 12.4 11.0 3.2 7.6 0.5 3.2 3 0 0 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 EMP24_GP25L PF01105.24 OEU07898.1 - 0.12 12.3 2.6 0.1 12.5 0.6 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FapA PF03961.13 OEU07898.1 - 0.25 9.9 5.0 1.3 7.6 1.9 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A ARTD15_N PF18084.1 OEU07898.1 - 0.29 11.4 7.9 6.4 7.1 0.4 3.7 3 2 0 3 3 3 0 ARTD15 N-terminal domain TSC22 PF01166.18 OEU07898.1 - 0.58 10.5 7.7 1.8 8.9 3.7 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.10 OEU07898.1 - 0.71 10.0 9.4 0.74 10.0 3.3 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-CpG_bind_C PF12269.8 OEU07898.1 - 2.2 8.0 5.9 1.1 8.9 2.9 1.9 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain GrpE PF01025.19 OEU07898.1 - 2.5 7.8 8.6 0.53 9.9 3.3 2.3 2 1 0 2 2 2 0 GrpE TerB_C PF15615.6 OEU07898.1 - 4.5 7.5 9.8 38 4.6 8.9 2.4 1 1 0 1 1 1 0 TerB-C domain RuBisCO_large_N PF02788.16 OEU07899.1 - 0.00041 20.5 0.9 0.00045 20.4 0.9 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain Pirin PF02678.16 OEU07901.1 - 1e-23 83.4 0.1 1.9e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 OEU07901.1 - 1.3e-20 73.7 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Lipase_3 PF01764.25 OEU07902.1 - 2.6e-15 56.5 0.0 8.3e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) 2OG-FeII_Oxy_2 PF13532.6 OEU07903.1 - 1.1e-14 55.1 0.1 2.2e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3446 PF11928.8 OEU07903.1 - 0.072 13.4 1.4 6.7 7.1 0.2 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain YafQ_toxin PF15738.5 OEU07904.1 - 0.0028 17.9 0.0 0.0064 16.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ Rubredoxin_2 PF18073.1 OEU07904.1 - 0.046 13.4 0.1 0.046 13.4 0.1 4.3 4 0 0 4 4 4 0 Rubredoxin metal binding domain DENN PF02141.21 OEU07905.1 - 2.2e-44 151.7 6.1 3.3e-44 151.1 6.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OEU07905.1 - 5.5e-14 52.7 0.2 5.5e-14 52.7 0.2 2.1 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OEU07905.1 - 7.8e-09 35.4 2.0 2.4e-08 33.8 2.0 1.9 1 0 0 1 1 1 1 dDENN domain zf-ribbon_3 PF13248.6 OEU07905.1 - 0.0082 15.5 4.9 0.13 11.7 0.4 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_9 PF14369.6 OEU07905.1 - 2.6 8.4 11.2 1.1 9.5 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon PseudoU_synth_2 PF00849.22 OEU07906.1 - 1.1e-13 51.6 0.1 3.3e-13 50.0 0.1 1.9 1 0 0 1 1 1 1 RNA pseudouridylate synthase EF-hand_1 PF00036.32 OEU07906.1 - 4.2e-08 32.2 1.5 0.0083 15.6 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU07906.1 - 1.5e-06 28.5 1.0 4.9e-06 26.9 1.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU07906.1 - 4.4e-06 26.2 3.4 0.034 14.1 0.8 2.9 2 0 0 2 2 2 2 EF-hand domain S4 PF01479.25 OEU07906.1 - 1.5e-05 24.6 0.4 4.1e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 S4 domain EF-hand_8 PF13833.6 OEU07906.1 - 2.2e-05 24.2 4.2 0.024 14.5 0.4 3.5 2 1 1 3 3 3 2 EF-hand domain pair zf-U1 PF06220.12 OEU07907.1 - 7.5e-06 25.6 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 OEU07907.1 - 0.007 16.6 1.7 0.034 14.5 1.7 2.1 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ntox1 PF15500.6 OEU07907.1 - 8.2 6.8 9.4 19 5.7 0.0 3.1 3 0 0 3 3 3 0 Putative RNase-like toxin, toxin_1 WD40 PF00400.32 OEU07909.1 - 5e-32 109.4 28.9 2.2e-08 34.6 0.0 10.5 10 1 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU07909.1 - 7.4e-07 29.4 4.0 0.71 10.2 0.0 6.9 7 1 2 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU07909.1 - 0.24 10.3 1.4 7.4 5.4 0.0 3.6 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GRIP PF01465.20 OEU07910.1 - 0.00052 19.9 0.1 0.0021 17.9 0.1 2.1 1 0 0 1 1 1 1 GRIP domain Pox_E8 PF03394.13 OEU07910.1 - 0.066 12.8 3.0 0.068 12.7 1.1 1.9 2 0 0 2 2 2 0 Poxvirus E8 protein DUF1213 PF06740.12 OEU07910.1 - 3.4 8.3 0.0 3.4 8.3 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1213) PPV_E1_N PF00524.18 OEU07911.1 - 0.6 10.5 0.1 0.6 10.5 0.1 2.2 3 0 0 3 3 3 0 E1 Protein, N terminal domain Histone PF00125.24 OEU07912.1 - 4.8e-20 72.2 0.6 5.9e-20 72.0 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OEU07912.1 - 0.00029 21.3 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 OEU07912.1 - 0.0025 17.9 0.2 0.003 17.6 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CBFD_NFYB_HMF PF00808.23 OEU07912.1 - 0.0049 17.1 1.2 0.0055 17.0 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C3HC4 PF00097.25 OEU07913.1 - 8.9e-09 35.1 8.7 1.8e-08 34.1 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU07913.1 - 2.2e-07 31.1 9.1 4.1e-07 30.2 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU07913.1 - 4.2e-07 29.7 8.5 4.2e-07 29.7 8.5 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU07913.1 - 5.7e-07 29.5 2.2 5.7e-07 29.5 2.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU07913.1 - 1.4e-06 28.4 3.5 3.7e-06 27.0 3.5 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OEU07913.1 - 2.3e-06 27.3 10.6 1.2e-05 25.0 10.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU07913.1 - 1.9e-05 24.5 9.4 4e-05 23.5 9.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OEU07913.1 - 9.1e-05 22.3 4.2 0.00018 21.3 4.2 1.6 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OEU07913.1 - 0.00014 21.7 7.0 0.00044 20.0 7.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_PP31 PF05311.11 OEU07913.1 - 0.00041 19.9 8.1 0.0006 19.4 8.1 1.2 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) SAP PF02037.27 OEU07913.1 - 0.00048 19.8 0.1 0.00094 18.9 0.1 1.5 1 0 0 1 1 1 1 SAP domain Cwf_Cwc_15 PF04889.12 OEU07913.1 - 0.0065 16.2 20.1 0.0085 15.9 20.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Baculo_IE-1 PF05290.11 OEU07913.1 - 0.011 15.7 1.4 0.018 15.0 1.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) ORC6 PF05460.13 OEU07913.1 - 0.015 14.6 9.9 0.021 14.1 9.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nucleo_P87 PF07267.11 OEU07913.1 - 0.04 12.8 12.5 0.054 12.4 12.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-Nse PF11789.8 OEU07913.1 - 0.041 13.7 2.7 0.082 12.7 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OEU07913.1 - 0.051 13.4 4.8 0.15 11.9 4.8 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BUD22 PF09073.10 OEU07913.1 - 0.1 11.9 16.4 0.12 11.7 16.4 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 OEU07913.1 - 0.14 11.5 29.7 0.4 10.0 29.7 1.6 1 1 0 1 1 1 0 NOA36 protein zf-rbx1 PF12678.7 OEU07913.1 - 0.15 12.4 9.1 0.61 10.4 9.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OEU07913.1 - 0.18 11.6 2.8 0.63 9.8 2.8 1.9 1 1 0 1 1 1 0 RING-like zinc finger PPP4R2 PF09184.11 OEU07913.1 - 0.19 11.3 18.9 0.27 10.8 18.9 1.3 1 0 0 1 1 1 0 PPP4R2 zf-RING_10 PF16685.5 OEU07913.1 - 0.2 11.8 7.9 0.73 10.0 7.9 2.1 1 1 0 1 1 1 0 zinc RING finger of MSL2 UPF0547 PF10571.9 OEU07913.1 - 0.69 10.1 5.5 0.19 11.8 1.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Astro_capsid_p PF12226.8 OEU07913.1 - 1.3 8.1 12.2 1.8 7.6 12.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Zip PF02535.22 OEU07913.1 - 2.3 7.3 9.1 3.1 6.9 9.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Zn-ribbon_8 PF09723.10 OEU07913.1 - 3.5 7.8 8.6 13 6.0 1.7 2.6 1 1 1 2 2 2 0 Zinc ribbon domain SLC12 PF03522.15 OEU07913.1 - 7.5 5.4 12.0 9.1 5.2 12.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ribosomal_L23 PF00276.20 OEU07914.1 - 3.1e-16 59.5 0.8 3.1e-16 59.5 0.8 2.0 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 OEU07914.1 - 1.2e-12 47.8 8.9 2.3e-12 46.9 8.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain WGG PF10273.9 OEU07916.1 - 1.9e-16 60.5 0.0 3.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Pro_isomerase PF00160.21 OEU07917.1 - 3e-36 125.1 0.0 4.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GRDB PF07355.12 OEU07917.1 - 0.19 10.9 0.1 0.28 10.4 0.1 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) FA_hydroxylase PF04116.13 OEU07918.1 - 2.2e-06 28.1 0.8 4.8e-06 27.0 0.8 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF4431 PF14485.6 OEU07918.1 - 0.11 12.4 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) Myb_DNA-binding PF00249.31 OEU07919.1 - 6.5e-08 32.6 0.2 1.3e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PAP_fibrillin PF04755.12 OEU07920.1 - 7.6e-17 61.9 0.0 4.5e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 PAP_fibrillin DUF498 PF04430.14 OEU07921.1 - 1.3e-15 57.4 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Golgin_A5 PF09787.9 OEU07922.1 - 8.7e-09 35.3 0.0 8.7e-09 35.3 0.0 4.7 3 2 2 5 5 5 2 Golgin subfamily A member 5 Myb_DNA-binding PF00249.31 OEU07923.1 - 2.5e-09 37.2 0.0 9.8e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Propep_M14 PF02244.16 OEU07923.1 - 0.0034 17.8 0.5 0.012 16.0 0.5 2.0 1 0 0 1 1 1 1 Carboxypeptidase activation peptide CitMHS PF03600.16 OEU07924.1 - 8.9e-25 87.5 0.2 2.1e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 OEU07924.1 - 0.0081 15.5 2.9 0.0081 15.5 2.9 2.5 3 0 0 3 3 3 1 Arsenical pump membrane protein DUF974 PF06159.13 OEU07925.1 - 4.9e-50 170.6 0.0 7.1e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 OEU07925.1 - 0.04 13.3 6.7 1.5 8.1 0.0 3.6 4 0 0 4 4 4 0 TRAPP trafficking subunit Trs65 MMU163 PF17119.5 OEU07927.1 - 1.9 7.6 11.5 0.17 11.0 6.1 1.9 1 1 1 2 2 2 0 Mitochondrial protein up-regulated during meiosis Aminotran_1_2 PF00155.21 OEU07928.1 - 7.7e-52 176.6 0.0 1.1e-51 176.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OEU07928.1 - 0.00025 20.5 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OEU07928.1 - 0.00049 19.5 0.5 0.0016 17.8 0.4 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 OEU07928.1 - 0.0068 15.2 0.0 0.013 14.3 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OEU07928.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OEU07928.1 - 0.095 11.2 0.0 0.18 10.3 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CCT PF06203.14 OEU07930.1 - 4.5e-16 58.6 6.0 4.5e-16 58.6 6.0 2.6 2 0 0 2 2 2 1 CCT motif CCT_2 PF09425.10 OEU07930.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 Divergent CCT motif RYDR_ITPR PF01365.21 OEU07930.1 - 0.82 9.1 6.4 2.3 7.6 6.4 1.7 1 0 0 1 1 1 0 RIH domain Mito_carr PF00153.27 OEU07933.1 - 1.3e-48 162.8 0.7 1.4e-17 63.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2235 PF09994.9 OEU07934.1 - 0.016 14.6 0.7 0.023 14.1 0.7 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SUIM_assoc PF16619.5 OEU07934.1 - 1.1 9.4 7.8 0.15 12.2 0.5 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TIMELESS PF04821.14 OEU07935.1 - 8.1e-52 176.2 5.5 2.9e-51 174.4 5.5 2.0 1 0 0 1 1 1 1 Timeless protein Coiled-coil_56 PF09813.9 OEU07935.1 - 0.0052 16.8 1.0 0.35 11.0 0.0 3.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 Sec7_N PF12783.7 OEU07935.1 - 1.9 8.4 5.3 6.5 6.6 0.8 3.1 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.32 OEU07936.1 - 2.5e-05 24.9 7.2 0.076 13.9 0.1 6.1 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU07936.1 - 0.00035 20.8 0.3 5.1 7.5 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 OEU07936.1 - 0.024 14.3 0.0 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split PAP2 PF01569.21 OEU07937.1 - 3.3e-06 26.9 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OEU07937.1 - 0.066 12.9 0.8 1 9.0 0.0 2.1 1 1 2 3 3 3 0 PAP2 superfamily CAP_N PF01213.19 OEU07939.1 - 0.0013 18.3 3.1 0.0015 18.1 3.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OEU07939.1 - 0.009 16.1 4.7 0.01 15.9 4.7 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator VIR_N PF15912.5 OEU07939.1 - 0.027 14.1 0.5 0.029 14.0 0.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 OEU07939.1 - 0.2 11.7 5.9 0.29 11.2 5.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HA PF03457.14 OEU07940.1 - 4.1e-39 132.7 1.8 1.2e-18 67.2 0.2 2.1 2 0 0 2 2 2 2 Helicase associated domain IstB_IS21_ATP PF08483.11 OEU07940.1 - 0.0013 18.6 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding N-terminal PGBA_C PF15437.6 OEU07940.1 - 0.33 11.3 7.5 0.72 10.2 0.4 2.4 1 1 1 2 2 2 0 Plasminogen-binding protein pgbA C-terminal MLANA PF14991.6 OEU07940.1 - 2 8.7 8.8 2.3 8.5 1.4 2.4 1 1 0 2 2 2 0 Protein melan-A TauE PF01925.19 OEU07942.1 - 1.6e-23 83.6 0.8 4.2e-11 42.9 1.5 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Aldo_ket_red PF00248.21 OEU07943.1 - 3.1e-14 52.9 0.6 1.2e-13 51.0 0.6 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Pilin_N PF07790.11 OEU07943.1 - 0.59 11.1 3.9 0.22 12.5 0.9 1.9 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal BTB_2 PF02214.22 OEU07944.1 - 8.4e-16 58.1 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU07944.1 - 0.0029 17.7 0.0 0.0086 16.2 0.0 1.8 2 1 0 2 2 2 1 BTB/POZ domain DUF2140 PF09911.9 OEU07945.1 - 0.076 12.6 0.8 0.18 11.4 0.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) tRNA_bind PF01588.20 OEU07949.1 - 4.6e-08 33.1 0.0 1.1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Putative tRNA binding domain SET PF00856.28 OEU07950.1 - 2.7e-09 37.6 1.3 2.7e-09 37.6 1.3 2.9 2 2 0 2 2 2 1 SET domain UPF0564 PF10595.9 OEU07950.1 - 0.00037 19.7 2.5 0.00037 19.7 2.5 2.1 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 SR-25 PF10500.9 OEU07950.1 - 1.1 8.8 19.3 2.3 7.8 19.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein K_channel_TID PF07941.11 OEU07950.1 - 6.4 7.3 8.5 0.24 11.9 2.1 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Hamartin PF04388.12 OEU07951.1 - 0.19 10.4 9.5 0.24 10.0 9.5 1.1 1 0 0 1 1 1 0 Hamartin protein PT PF04886.12 OEU07953.1 - 2e-11 43.3 23.8 2.2e-06 27.1 8.4 2.3 1 1 1 2 2 2 2 PT repeat Yae1_N PF09811.9 OEU07954.1 - 0.00053 19.6 32.8 4.1 7.2 0.1 10.8 6 4 3 9 9 9 6 Essential protein Yae1, N terminal FHIPEP PF00771.20 OEU07955.1 - 0.0018 16.9 2.7 0.0025 16.3 2.6 1.4 1 1 0 1 1 1 1 FHIPEP family Presenilin PF01080.17 OEU07955.1 - 0.0026 16.6 7.9 0.0034 16.2 7.9 1.2 1 0 0 1 1 1 1 Presenilin R3H-assoc PF13902.6 OEU07955.1 - 0.0074 16.7 8.1 0.012 16.0 4.3 2.4 2 0 0 2 2 2 1 R3H-associated N-terminal domain DUF1682 PF07946.14 OEU07955.1 - 0.011 14.9 6.4 0.017 14.4 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TFIIA PF03153.13 OEU07955.1 - 0.013 15.5 15.0 0.02 14.9 15.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 OEU07955.1 - 0.016 13.6 3.6 0.019 13.4 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Androgen_recep PF02166.16 OEU07955.1 - 0.018 13.9 7.4 0.03 13.2 7.4 1.4 1 0 0 1 1 1 0 Androgen receptor Ferlin_C PF16165.5 OEU07955.1 - 0.035 14.1 3.1 0.14 12.1 0.9 2.3 2 0 0 2 2 2 0 Ferlin C-terminus Neur_chan_memb PF02932.16 OEU07955.1 - 0.068 13.2 2.9 0.1 12.7 2.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 OEU07955.1 - 0.08 12.5 27.2 0.36 10.4 18.1 2.5 2 0 0 2 2 2 0 Spt20 family SLY PF12485.8 OEU07955.1 - 0.12 13.1 8.9 0.05 14.3 4.1 2.3 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein HNOBA PF07701.14 OEU07955.1 - 0.16 11.4 7.5 0.14 11.6 2.6 2.2 2 0 0 2 2 2 0 Heme NO binding associated DUF3506 PF12014.8 OEU07955.1 - 0.33 10.9 6.7 4.5 7.3 3.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3506) Sec62 PF03839.16 OEU07955.1 - 0.34 10.4 8.9 0.81 9.2 4.7 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Peptidase_S49_N PF08496.10 OEU07955.1 - 0.36 10.9 8.9 0.88 9.6 4.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FlaG PF03646.15 OEU07955.1 - 0.51 10.5 21.8 0.83 9.9 15.0 2.7 2 1 0 2 2 2 0 FlaG protein ANAPC_CDC26 PF10471.9 OEU07955.1 - 0.82 10.5 24.4 0.59 11.0 13.6 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 NST1 PF13945.6 OEU07955.1 - 1.1 9.3 25.5 0.98 9.5 18.9 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator AFT PF08731.11 OEU07955.1 - 1.3 9.5 12.4 1.4 9.3 8.0 2.6 2 1 0 2 2 2 0 Transcription factor AFT EIIBC-GUT_N PF03612.14 OEU07955.1 - 1.5 8.5 11.3 1.7 8.3 5.6 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3381 PF11861.8 OEU07955.1 - 1.7 8.4 17.8 6.5 6.5 12.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TERB2 PF15101.6 OEU07955.1 - 2.8 7.9 13.5 16 5.4 8.8 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 OEU07955.1 - 5.3 8.1 19.9 1.8 9.6 9.2 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) DDHD PF02862.17 OEU07955.1 - 5.5 7.1 17.4 7.2 6.7 16.3 1.8 1 1 0 1 1 1 0 DDHD domain Adaptin_binding PF10199.9 OEU07955.1 - 6.6 7.4 18.6 12 6.5 18.4 1.5 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 RabGAP-TBC PF00566.18 OEU07955.1 - 7.9 6.1 15.2 0.42 10.2 8.8 1.8 2 0 0 2 2 2 0 Rab-GTPase-TBC domain CLN3 PF02487.17 OEU07955.1 - 8.1 5.4 10.3 26 3.7 10.0 1.8 1 1 0 1 1 1 0 CLN3 protein FAM91_C PF14648.6 OEU07955.1 - 9.6 4.9 15.1 1.4 7.6 6.9 2.1 1 1 1 2 2 2 0 FAM91 C-terminus PT PF04886.12 OEU07958.1 - 3.5e-15 55.2 44.8 0.33 10.5 44.8 2.7 1 1 0 1 1 1 1 PT repeat TMEM51 PF15345.6 OEU07959.1 - 0.0065 16.3 8.7 0.0065 16.3 8.7 2.0 1 1 1 2 2 2 1 Transmembrane protein 51 GSH_synth_ATP PF03917.17 OEU07961.1 - 7.4e-108 360.7 0.0 1e-107 360.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OEU07961.1 - 4.7e-31 107.3 0.0 1.1e-30 106.1 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase GSH_synth_ATP PF03917.17 OEU07962.1 - 7.6e-112 373.8 0.0 9.1e-112 373.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OEU07962.1 - 5.1e-31 107.2 0.0 1.4e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Nramp PF01566.18 OEU07963.1 - 5.5e-71 239.4 9.5 6.9e-71 239.1 9.5 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Nramp PF01566.18 OEU07964.1 - 9.4e-71 238.7 9.5 1.2e-70 238.3 9.5 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Aminotran_1_2 PF00155.21 OEU07965.1 - 3.1e-54 184.5 0.0 3.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4931 PF16285.5 OEU07965.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) Methyltransf_11 PF08241.12 OEU07966.1 - 3.4e-24 85.3 0.0 1.1e-23 83.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU07966.1 - 3.9e-23 82.0 0.0 7.2e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU07966.1 - 4.6e-22 78.4 0.0 7.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU07966.1 - 5.2e-19 68.7 0.0 8.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU07966.1 - 1.4e-16 61.0 0.0 2.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU07966.1 - 2.5e-13 49.9 0.0 4.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OEU07966.1 - 3e-12 46.4 0.0 4.2e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 OEU07966.1 - 2.3e-07 29.8 0.0 3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 OEU07966.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OEU07966.1 - 7.9e-05 22.2 0.0 0.0012 18.3 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OEU07966.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OEU07966.1 - 0.00044 20.4 0.0 0.0092 16.1 0.0 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 OEU07966.1 - 0.0019 19.2 0.0 0.0041 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OEU07966.1 - 0.0051 16.4 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 OEU07966.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spermine_synth PF01564.17 OEU07966.1 - 0.058 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltr_RsmB-F PF01189.17 OEU07966.1 - 0.08 12.6 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 OEU07966.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 OEU07966.1 - 0.097 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 OEU07966.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin ADH_zinc_N PF00107.26 OEU07966.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrmA PF06325.13 OEU07966.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Fasciclin PF02469.22 OEU07967.1 - 9.3e-15 55.0 0.0 1.3e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain PetN PF03742.14 OEU07967.1 - 0.0077 16.1 0.0 83 3.2 0.0 4.2 4 0 0 4 4 4 3 PetN BUD22 PF09073.10 OEU07969.1 - 7.5 5.8 11.1 8.3 5.6 11.1 1.0 1 0 0 1 1 1 0 BUD22 DUF5443 PF17518.2 OEU07970.1 - 0.014 14.4 0.3 0.018 14.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5443) PRA-CH PF01502.18 OEU07970.1 - 0.52 10.2 3.1 0.87 9.5 1.7 2.1 1 1 1 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase 2OG-FeII_Oxy_3 PF13640.6 OEU07971.1 - 2.7e-11 44.2 0.0 6.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU07971.1 - 0.084 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NARG2_C PF10505.9 OEU07972.1 - 0.0024 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Chordopox_G3 PF06129.12 OEU07972.1 - 0.12 13.0 4.2 3.6 8.3 0.1 2.6 2 1 1 3 3 3 0 Chordopoxvirus G3 protein PT PF04886.12 OEU07974.1 - 2.5e-07 30.1 24.1 0.00027 20.4 24.1 2.8 1 1 0 1 1 1 1 PT repeat Glycoprotein_G PF00802.19 OEU07974.1 - 0.16 11.3 8.0 0.16 11.3 8.0 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF4106 PF13388.6 OEU07974.1 - 0.62 9.2 9.7 0.64 9.2 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Trypan_PARP PF05887.11 OEU07974.1 - 0.77 9.7 9.4 0.84 9.6 9.4 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PT PF04886.12 OEU07975.1 - 2e-08 33.7 124.6 1.8e+04 -81.7 124.6 6.0 1 1 0 1 1 1 0 PT repeat M_domain PF12938.7 OEU07975.1 - 1.5 8.6 10.0 2.1 8.1 2.0 2.2 2 0 0 2 2 2 0 M domain of GW182 PT PF04886.12 OEU07976.1 - 5.2e-06 25.9 24.1 0.001 18.6 19.3 3.0 1 1 1 2 2 2 2 PT repeat TMEM208_SND2 PF05620.11 OEU07977.1 - 1e-16 61.2 0.3 1.5e-16 60.6 0.3 1.2 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 SecD-TM1 PF13721.6 OEU07977.1 - 0.039 14.4 0.0 0.086 13.3 0.0 1.5 1 0 0 1 1 1 0 SecD export protein N-terminal TM region UT PF03253.14 OEU07978.1 - 1.1e-80 270.9 23.3 1.3e-80 270.7 23.3 1.0 1 0 0 1 1 1 1 Urea transporter Gly-zipper_Omp PF13488.6 OEU07978.1 - 0.43 10.6 6.7 1 9.4 2.3 2.5 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 OEU07978.1 - 1.2 8.9 6.2 5.9 6.7 1.4 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper BTB PF00651.31 OEU07979.1 - 4.2e-05 23.7 0.0 0.00022 21.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Clavanin PF05452.11 OEU07979.1 - 0.012 15.8 0.1 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 Clavanin DUF1415 PF07209.12 OEU07980.1 - 8.5e-46 155.8 0.0 1.3e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) cobW PF02492.19 OEU07981.1 - 2.4e-39 134.7 1.6 5e-39 133.7 1.6 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU07981.1 - 4.2e-18 65.0 0.0 1.7e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 OEU07981.1 - 0.015 15.9 0.8 0.07 13.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU07981.1 - 0.05 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ETRAMP PF09716.10 OEU07981.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RsgA_GTPase PF03193.16 OEU07981.1 - 2.3 8.1 8.8 1.2 9.0 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase PYST-C1 PF09690.10 OEU07982.1 - 0.009 15.7 2.2 0.009 15.7 2.2 3.8 3 0 0 3 3 3 1 Plasmodium yoelii subtelomeric region (PYST-C1) Sec62 PF03839.16 OEU07982.1 - 0.0096 15.5 1.6 0.21 11.1 0.5 2.3 2 0 0 2 2 2 2 Translocation protein Sec62 Rrp44_CSD1 PF17216.3 OEU07982.1 - 0.049 13.4 6.5 0.066 12.9 1.2 2.6 2 0 0 2 2 2 0 Rrp44-like cold shock domain HSF_DNA-bind PF00447.17 OEU07983.1 - 3.7e-13 49.9 0.1 4.1e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding TPR_2 PF07719.17 OEU07984.1 - 8.5e-05 22.4 4.1 0.0039 17.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU07984.1 - 8.6e-05 22.7 7.1 0.0055 17.0 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU07984.1 - 0.0006 19.5 2.0 0.085 12.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU07984.1 - 0.006 16.7 1.9 0.11 12.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU07984.1 - 0.018 15.0 8.9 0.78 9.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MMR1 PF08505.10 OEU07984.1 - 0.019 15.3 11.2 0.058 13.7 10.7 2.0 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TPR_10 PF13374.6 OEU07984.1 - 0.02 14.7 4.0 14 5.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 OEU07984.1 - 0.079 13.7 0.0 11 6.9 0.0 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_11 PF13414.6 OEU07984.1 - 0.081 12.6 0.1 0.081 12.6 0.1 3.1 3 0 0 3 3 3 0 TPR repeat MIT PF04212.18 OEU07984.1 - 0.082 13.0 2.7 0.74 9.9 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF5352 PF17303.2 OEU07984.1 - 1.4 8.8 12.4 0.16 11.8 2.4 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5352) DUF4834 PF16118.5 OEU07984.1 - 7.2 7.7 10.7 8.8 7.4 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_M11 PF05548.11 OEU07985.1 - 3.9e-07 29.5 0.1 6.4e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_4 PF13583.6 OEU07985.1 - 0.00049 19.8 0.1 0.00088 19.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OEU07985.1 - 0.0006 18.9 0.3 0.0011 18.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 OEU07985.1 - 0.0039 17.0 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 OEU07985.1 - 0.024 15.2 0.0 0.095 13.2 0.0 2.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ShK PF01549.24 OEU07985.1 - 1.5 9.4 5.4 2.5 8.7 0.9 2.5 2 0 0 2 2 2 0 ShK domain-like DUF285 PF03382.14 OEU07986.1 - 1.2e-56 189.7 30.8 8.8e-30 103.0 11.6 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Roc PF08477.13 OEU07986.1 - 0.018 15.3 0.4 0.58 10.4 0.2 2.6 1 1 2 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Bromodomain PF00439.25 OEU07986.1 - 0.043 13.9 5.5 18 5.5 0.3 4.2 4 1 0 4 4 4 0 Bromodomain Glyco_transf_11 PF01531.16 OEU07987.1 - 0.018 14.3 0.5 0.056 12.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 11 CCDC53 PF10152.9 OEU07987.1 - 0.12 12.8 1.7 0.2 12.1 1.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Chlorophyllase2 PF12740.7 OEU07988.1 - 6.9e-10 38.3 0.0 1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OEU07988.1 - 0.00051 19.1 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 OEU07988.1 - 0.11 11.0 0.0 0.54 8.7 0.0 1.9 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2633 PF11119.8 OEU07992.1 - 3.2e-05 23.7 1.1 9.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2633) DUF5383 PF17355.2 OEU07992.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5383) DUF4834 PF16118.5 OEU07992.1 - 2.3 9.2 10.6 3.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) FAM199X PF15814.5 OEU07992.1 - 3.7 6.5 13.1 0.38 9.8 7.0 1.9 2 0 0 2 2 2 0 Protein family FAM199X Dickkopf_N PF04706.12 OEU07994.1 - 0.013 15.9 0.3 0.013 15.9 0.3 1.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 OEU07994.1 - 0.014 15.7 0.1 0.014 15.7 0.1 1.7 2 0 0 2 2 2 0 EB module DUF2190 PF09956.9 OEU07994.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Peptidase_M20 PF01546.28 OEU07995.1 - 1.2e-17 64.3 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Response_reg PF00072.24 OEU07998.1 - 1e-18 67.5 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain SNF2_N PF00176.23 OEU07999.1 - 1.4e-25 89.8 0.0 7.5e-18 64.4 0.0 2.5 2 1 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 OEU07999.1 - 2.1e-12 47.4 0.0 4.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU07999.1 - 1.3e-10 41.6 0.0 1.2e-08 35.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU07999.1 - 2.3e-07 30.8 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OEU07999.1 - 0.048 13.3 0.0 0.29 10.8 0.0 2.3 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 OEU07999.1 - 0.12 12.6 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OEU07999.1 - 0.15 11.3 0.0 0.31 10.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_34 PF13872.6 OEU07999.1 - 0.18 10.6 0.0 7.5 5.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 SDA1 PF05285.12 OEU08000.1 - 8.5 5.7 16.9 12 5.2 16.9 1.1 1 0 0 1 1 1 0 SDA1 zf-met2 PF12907.7 OEU08001.1 - 5.1e-13 48.9 0.3 8e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding DBR1 PF05011.13 OEU08002.1 - 6e-17 62.4 0.3 1.2e-16 61.4 0.3 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OEU08002.1 - 4.8e-11 43.5 0.1 7.4e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EXS PF03124.14 OEU08005.1 - 1.2e-63 215.4 9.6 1.7e-63 215.0 9.6 1.2 1 0 0 1 1 1 1 EXS family HA PF03457.14 OEU08008.1 - 1.4e-26 92.6 3.3 3.3e-14 52.9 0.3 2.2 2 0 0 2 2 2 2 Helicase associated domain Mpv17_PMP22 PF04117.12 OEU08009.1 - 1.3e-07 31.7 0.3 3.2e-07 30.5 0.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family SUI1 PF01253.22 OEU08010.1 - 5.2e-13 49.3 0.3 5.2e-13 49.3 0.3 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 Ferlin_C PF16165.5 OEU08010.1 - 8.4 6.3 10.6 2.4 8.1 3.2 2.2 1 1 1 2 2 2 0 Ferlin C-terminus DUF2615 PF11027.8 OEU08011.1 - 0.0022 18.1 0.1 0.0038 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Dicty_REP PF05086.12 OEU08011.1 - 0.021 12.9 2.0 0.026 12.5 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FtsH_ext PF06480.15 OEU08011.1 - 1.6 9.1 4.9 3.2 8.1 4.9 1.5 1 1 0 1 1 1 0 FtsH Extracellular DUF563 PF04577.14 OEU08012.1 - 1.3e-14 54.9 0.2 2.8e-14 53.8 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_C1 PF00112.23 OEU08014.1 - 1.4e-53 182.2 1.6 2.9e-53 181.2 1.6 1.5 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OEU08014.1 - 1.6e-15 57.2 5.6 1.6e-15 57.2 5.6 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OEU08014.1 - 1e-06 27.8 0.7 0.0014 17.5 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family zf-CCHC_5 PF14787.6 OEU08015.1 - 0.08 12.7 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PT PF04886.12 OEU08015.1 - 2.9 7.5 20.7 20 4.8 20.7 2.3 1 1 0 1 1 1 0 PT repeat DJ-1_PfpI PF01965.24 OEU08018.1 - 3.4e-12 46.5 0.0 8.3e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 OEU08018.1 - 0.13 11.4 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain DUF4718 PF15842.5 OEU08020.1 - 9.8 5.9 7.7 2 8.2 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) DTW PF03942.15 OEU08021.1 - 1.9e-08 34.3 0.8 9e-07 28.8 0.1 2.3 2 0 0 2 2 2 2 DTW domain DUF1754 PF08555.10 OEU08021.1 - 0.53 11.1 24.7 0.68 10.8 15.7 2.7 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Sec16 PF12932.7 OEU08021.1 - 0.58 10.8 9.6 1.2 9.7 3.9 2.5 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Secretin_N_2 PF07655.13 OEU08021.1 - 3.3 8.3 9.0 0.25 11.9 2.4 2.3 2 1 1 3 3 3 0 Secretin N-terminal domain AAA_11 PF13086.6 OEU08021.1 - 4.4 7.0 10.0 3.5 7.3 8.5 1.5 1 1 1 2 2 2 0 AAA domain DTW PF03942.15 OEU08022.1 - 1.1e-09 38.3 1.5 1.8e-09 37.6 1.5 1.3 1 0 0 1 1 1 1 DTW domain zinc_ribbon_16 PF17034.5 OEU08022.1 - 0.027 14.7 4.3 0.037 14.2 4.0 1.4 1 1 0 1 1 1 0 Zinc-ribbon like family CCDC106 PF15794.5 OEU08022.1 - 0.23 11.2 7.6 0.32 10.7 7.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ribosomal_L37e PF01907.19 OEU08022.1 - 1.9 8.7 6.9 0.89 9.8 2.9 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e HAUS-augmin3 PF14932.6 OEU08023.1 - 2.3 7.7 18.7 0.053 13.1 10.5 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Dynactin_p22 PF07426.11 OEU08025.1 - 0.00037 20.4 4.4 0.021 14.7 0.7 3.3 3 1 1 4 4 4 2 Dynactin subunit p22 Suf PF05843.14 OEU08025.1 - 0.098 12.6 4.8 0.066 13.2 3.2 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 OEU08025.1 - 0.14 11.8 12.6 0.018 14.7 3.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Iron_traffic PF04362.14 OEU08027.1 - 0.054 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking RNA_polI_A34 PF08208.11 OEU08028.1 - 0.32 11.1 17.8 0.32 11.1 15.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 OEU08028.1 - 3.3 7.5 14.1 9.9 6.0 14.1 1.8 1 0 0 1 1 1 0 Coilin N-terminus Med19 PF10278.9 OEU08028.1 - 8.3 6.3 15.7 17 5.3 15.7 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_M41 PF01434.18 OEU08031.1 - 5.6e-57 192.7 0.1 8.9e-57 192.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OEU08031.1 - 4e-45 153.5 0.3 3e-44 150.6 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU08031.1 - 5e-13 48.6 0.1 1.1e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 OEU08031.1 - 0.00014 21.2 0.1 0.00027 20.3 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain FtsH_ext PF06480.15 OEU08031.1 - 0.00099 19.4 0.5 0.0031 17.8 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular RuvB_N PF05496.12 OEU08031.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OEU08031.1 - 0.0038 17.6 0.1 0.085 13.2 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OEU08031.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OEU08031.1 - 0.0091 16.0 1.1 0.033 14.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU08031.1 - 0.015 15.6 0.6 0.13 12.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 OEU08031.1 - 0.027 14.6 0.0 0.068 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OEU08031.1 - 0.037 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 OEU08031.1 - 0.054 13.9 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OEU08031.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OEU08031.1 - 0.12 12.9 0.0 0.4 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU08031.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OEU08031.1 - 0.15 11.8 0.1 0.43 10.3 0.1 1.8 1 0 0 1 1 1 0 Cytidylate kinase FoP_duplication PF13865.6 OEU08031.1 - 2.9 8.5 6.2 75 4.0 4.1 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF4603 PF15376.6 OEU08032.1 - 0.18 9.2 3.1 0.19 9.1 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) L51_S25_CI-B8 PF05047.16 OEU08033.1 - 2.3e-05 24.2 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1794 PF08768.11 OEU08034.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Hormone_2 PF00123.20 OEU08035.1 - 0.39 10.6 1.4 3.1 7.8 1.4 2.2 1 1 0 1 1 1 0 Peptide hormone SET PF00856.28 OEU08037.1 - 1.4e-06 28.8 5.9 4.8e-05 23.8 0.1 3.9 3 2 0 3 3 3 2 SET domain PH_4 PF15404.6 OEU08037.1 - 0.68 9.7 7.2 0.49 10.2 3.2 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Fasciclin PF02469.22 OEU08038.1 - 4.4e-33 114.2 0.0 5.1e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain 7tm_3 PF00003.22 OEU08039.1 - 2.1e-18 66.9 26.6 2.1e-18 66.9 26.6 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Claudin_2 PF13903.6 OEU08039.1 - 0.0024 17.7 1.6 0.0024 17.7 1.6 2.7 2 1 3 5 5 5 1 PMP-22/EMP/MP20/Claudin tight junction ApoO PF09769.9 OEU08040.1 - 10 6.1 7.2 45 4.0 0.4 3.6 5 0 0 5 5 5 0 Apolipoprotein O NST1 PF13945.6 OEU08043.1 - 0.00043 20.5 7.3 0.00043 20.5 7.3 4.7 3 1 2 5 5 5 1 Salt tolerance down-regulator Sigma_reg_N PF13800.6 OEU08043.1 - 0.0039 17.4 1.9 0.0039 17.4 1.9 2.4 2 0 0 2 2 2 1 Sigma factor regulator N-terminal DUF3169 PF11368.8 OEU08043.1 - 0.025 14.1 0.5 0.066 12.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4199 PF13858.6 OEU08043.1 - 0.074 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4337 PF14235.6 OEU08043.1 - 0.45 10.6 5.4 0.34 11.0 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Shisa PF13908.6 OEU08043.1 - 0.69 10.1 10.0 0.54 10.5 7.8 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SR-25 PF10500.9 OEU08043.1 - 3.1 7.3 25.0 2 8.0 1.2 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein BTB PF00651.31 OEU08044.1 - 4.2e-05 23.7 0.9 0.0003 21.0 0.2 2.3 1 1 1 2 2 2 1 BTB/POZ domain zf-MYND PF01753.18 OEU08046.1 - 0.23 11.6 12.4 0.069 13.3 7.2 2.6 2 1 0 2 2 2 0 MYND finger MCC-bdg_PDZ PF10506.9 OEU08047.1 - 0.014 15.4 3.1 0.045 13.8 3.1 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome BTB PF00651.31 OEU08047.1 - 0.047 13.9 5.8 0.062 13.5 3.2 2.5 2 1 0 2 2 2 0 BTB/POZ domain UCH PF00443.29 OEU08048.1 - 2.5e-11 43.6 1.2 2.5e-11 43.6 1.2 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase NADPH_Ox PF08414.10 OEU08048.1 - 0.14 12.5 0.7 1.1 9.6 0.1 2.4 3 0 0 3 3 3 0 Respiratory burst NADPH oxidase TAA-Trp-ring PF15401.6 OEU08048.1 - 0.23 11.9 3.8 0.19 12.2 0.9 2.2 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin eIF-1a PF01176.19 OEU08050.1 - 1.1e-21 76.4 0.3 1.5e-21 75.9 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_S8e PF01201.22 OEU08051.1 - 8.8e-52 174.9 0.3 1e-51 174.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e PT PF04886.12 OEU08052.1 - 2.3e-14 52.6 56.2 2e-06 27.2 10.2 5.1 4 1 0 4 4 4 4 PT repeat HA PF03457.14 OEU08053.1 - 1.1e-11 44.9 0.2 2.6e-11 43.7 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain SDA1 PF05285.12 OEU08053.1 - 0.59 9.5 14.1 0.63 9.4 14.1 1.1 1 0 0 1 1 1 0 SDA1 NAD_Gly3P_dh_N PF01210.23 OEU08054.1 - 0.058 13.4 0.4 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CDC45 PF02724.14 OEU08056.1 - 0.076 11.3 0.1 0.071 11.4 0.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 OEU08056.1 - 0.74 7.8 3.1 0.78 7.7 3.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PKcGMP_CC PF16808.5 OEU08057.1 - 0.023 14.6 0.5 0.049 13.5 0.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SMYLE_N PF18615.1 OEU08057.1 - 0.21 11.1 9.5 0.25 10.9 9.5 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SSP160 PF06933.11 OEU08057.1 - 4.8 5.3 8.7 6.3 4.9 8.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2272 PF10030.9 OEU08058.1 - 0.15 11.8 4.6 0.4 10.4 4.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) GTP_EFTU PF00009.27 OEU08059.1 - 2.1e-29 102.5 0.1 5e-29 101.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OEU08059.1 - 1.9e-06 27.5 3.7 0.017 14.5 0.4 2.7 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OEU08059.1 - 2.3e-06 27.7 0.7 9.8e-06 25.6 0.7 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OEU08059.1 - 5.5e-05 23.5 0.1 0.00043 20.6 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 cobW PF02492.19 OEU08059.1 - 0.0093 15.6 1.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OEU08059.1 - 0.049 13.5 1.9 0.15 11.9 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase FAD_binding_1 PF00667.20 OEU08061.1 - 6.1e-31 107.7 0.0 1.3e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OEU08061.1 - 1.3e-14 54.7 0.0 2.6e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OEU08061.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain IMUP PF15761.5 OEU08061.1 - 0.37 11.5 8.2 0.087 13.5 2.8 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein LRR_8 PF13855.6 OEU08062.1 - 7.2e-07 28.9 7.5 0.01 15.6 2.8 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU08062.1 - 7.4e-07 29.4 11.6 0.12 12.8 0.1 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) SAM_Ste50p PF09235.10 OEU08062.1 - 0.042 14.1 0.1 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 OEU08062.1 - 0.35 11.6 9.8 1.1 10.1 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat Sulfate_transp PF00916.20 OEU08064.1 - 4.8e-98 328.4 23.9 6.4e-98 328.0 23.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OEU08064.1 - 1.5e-17 63.3 0.0 2.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OEU08064.1 - 0.023 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 STAS domain Shisa PF13908.6 OEU08065.1 - 0.0017 18.7 1.3 0.0057 16.9 1.3 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator zf-LITAF-like PF10601.9 OEU08065.1 - 0.0052 17.0 0.3 0.0076 16.5 0.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Herpes_gE PF02480.16 OEU08065.1 - 0.091 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ERM PF00769.19 OEU08067.1 - 0.026 14.4 32.6 0.026 14.4 17.6 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF948 PF06103.11 OEU08067.1 - 8.7 6.7 13.3 0.096 13.0 2.8 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SpoU_methylase PF00588.19 OEU08068.1 - 6.5e-25 88.0 0.0 7.3e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF5545 PF17699.1 OEU08068.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5545) DUF1573 PF07610.11 OEU08069.1 - 0.03 14.3 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) HhH-GPD PF00730.25 OEU08072.1 - 1.1e-08 35.5 0.0 1.3e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 OEU08072.1 - 0.00023 21.7 0.1 0.39 11.3 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.23 OEU08072.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 OEU08072.1 - 0.0014 18.7 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif SecA_DEAD PF07517.14 OEU08073.1 - 0.012 14.9 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain PT PF04886.12 OEU08074.1 - 1.9e-06 27.3 13.0 0.01 15.4 13.0 2.9 1 1 0 1 1 1 1 PT repeat PT PF04886.12 OEU08075.1 - 0.0037 16.8 27.8 0.17 11.5 7.1 4.4 2 2 0 2 2 2 2 PT repeat Pkinase PF00069.25 OEU08076.1 - 0.0014 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08076.1 - 0.0021 17.4 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mcp5_PH PF12814.7 OEU08076.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology V-SNARE PF05008.15 OEU08077.1 - 0.15 12.4 1.8 0.3 11.5 1.8 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CASP_C PF08172.12 OEU08077.1 - 0.23 10.8 0.4 0.38 10.1 0.4 1.3 1 0 0 1 1 1 0 CASP C terminal Lebercilin PF15619.6 OEU08077.1 - 0.29 10.8 2.1 0.55 9.9 2.1 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MetOD2 PF18548.1 OEU08077.1 - 0.62 10.2 2.3 1.2 9.3 2.3 1.4 1 0 0 1 1 1 0 Metanogen output domain 2 DUF2890 PF11081.8 OEU08077.1 - 2.6 8.1 5.1 6.7 6.8 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Cleaved_Adhesin PF07675.11 OEU08079.1 - 0.042 13.8 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Cleaved Adhesin Domain YscO-like PF16789.5 OEU08079.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.3 3 0 0 3 3 3 0 YscO-like protein SLS PF14611.6 OEU08079.1 - 5.2 6.8 11.8 19 5.0 0.8 3.6 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator Arc_PepC_II PF06847.11 OEU08082.1 - 0.00026 21.4 10.6 0.14 12.7 1.0 4.0 3 2 1 4 4 4 2 Archaeal Peptidase A24 C-terminus Type II SCO1-SenC PF02630.14 OEU08082.1 - 0.0045 16.9 1.5 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 SCO1/SenC Csm1_N PF18504.1 OEU08082.1 - 0.018 15.4 3.6 0.018 15.4 3.6 5.8 1 1 3 5 5 5 0 Csm1 N-terminal domain XhlA PF10779.9 OEU08082.1 - 0.087 13.0 0.7 0.087 13.0 0.7 6.1 4 1 2 6 6 5 0 Haemolysin XhlA Dicty_CAD PF05720.12 OEU08082.1 - 0.18 11.8 0.7 20 5.3 0.1 2.4 2 0 0 2 2 2 0 Cell-cell adhesion domain Hemocyanin_C PF03723.14 OEU08082.1 - 0.36 10.1 6.8 4.8 6.4 0.9 2.6 2 0 0 2 2 2 0 Hemocyanin, ig-like domain DUF883 PF05957.13 OEU08082.1 - 0.74 10.5 21.6 2.5 8.7 5.5 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HTH_22 PF13309.6 OEU08082.1 - 1.3 9.2 8.2 10 6.3 1.1 3.5 2 2 0 2 2 2 0 HTH domain YbbR PF07949.12 OEU08082.1 - 2 8.8 8.0 15 6.0 0.3 3.2 1 1 1 3 3 3 0 YbbR-like protein REPA_OB_2 PF16900.5 OEU08082.1 - 2.9 7.9 8.7 2.3 8.2 0.8 3.3 1 1 0 2 2 2 0 Replication protein A OB domain Cauli_DNA-bind PF03310.13 OEU08082.1 - 4.9 7.2 25.3 2.1 8.4 5.3 3.3 3 1 0 3 3 3 0 Caulimovirus DNA-binding protein HTH_Tnp_1 PF01527.20 OEU08083.1 - 4.6e-06 26.9 0.2 8.2e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 Transposase CENP-B_N PF04218.13 OEU08083.1 - 9.8e-05 21.9 0.4 0.00016 21.2 0.4 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 OEU08083.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_psq PF05225.16 OEU08083.1 - 0.0033 17.1 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 OEU08083.1 - 0.0053 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 OEU08083.1 - 0.0074 15.8 0.1 0.022 14.3 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Phage_terminase PF10668.9 OEU08083.1 - 0.015 15.3 0.2 0.05 13.6 0.0 1.8 2 0 0 2 2 2 0 Phage terminase small subunit DUF1804 PF08822.11 OEU08083.1 - 0.018 15.0 0.2 0.19 11.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1804) HTH_5 PF01022.20 OEU08083.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1836 PF08876.11 OEU08083.1 - 0.054 13.6 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) MarR_2 PF12802.7 OEU08083.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.16 OEU08083.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 GAGA_bind PF06217.12 OEU08085.1 - 0.024 14.9 8.4 0.44 10.8 3.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family PPV_E2_C PF00511.17 OEU08085.1 - 0.064 13.4 3.0 0.68 10.2 0.1 3.1 3 0 0 3 3 3 0 E2 (early) protein, C terminal Connexin PF00029.19 OEU08085.1 - 0.15 11.8 17.4 1.3 8.7 0.5 2.5 2 0 0 2 2 2 0 Connexin TFIIA PF03153.13 OEU08085.1 - 0.72 9.8 24.0 0.61 10.0 10.6 2.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 OEU08085.1 - 1.1 9.8 15.2 0.55 10.8 7.1 2.6 2 0 0 2 2 2 0 TCP family transcription factor Neur_chan_memb PF02932.16 OEU08085.1 - 2.3 8.2 6.4 2.6 8.0 2.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1764 PF08576.10 OEU08085.1 - 6.5 7.7 19.5 0.77 10.7 8.1 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_S49_N PF08496.10 OEU08085.1 - 9.5 6.3 17.0 5.5 7.0 0.5 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RabGAP-TBC PF00566.18 OEU08086.1 - 1.7e-33 116.1 16.9 1.7e-31 109.5 16.9 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Citrate_synt PF00285.21 OEU08086.1 - 0.068 12.2 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain UME PF08064.13 OEU08086.1 - 0.19 11.6 2.2 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 UME (NUC010) domain DUF2756 PF10956.8 OEU08086.1 - 0.41 11.2 12.3 0.83 10.2 12.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) DUF4834 PF16118.5 OEU08086.1 - 2.1 9.3 6.9 6.1 7.9 5.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 OEU08087.1 - 0.041 14.3 6.5 0.088 13.2 6.5 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Menin PF05053.13 OEU08087.1 - 0.35 9.2 9.5 0.39 9.0 9.0 1.4 1 1 0 1 1 1 0 Menin PBP1_TM PF14812.6 OEU08087.1 - 0.88 10.0 12.6 0.52 10.7 3.3 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_11 PF08241.12 OEU08088.1 - 2.6e-10 40.8 0.0 1.9e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU08088.1 - 2e-06 27.3 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU08088.1 - 3.9e-06 27.5 0.0 8.7e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU08088.1 - 1.1e-05 26.1 0.0 2.4e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU08088.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU08088.1 - 0.0022 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 OEU08088.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 DNA methylase ADH_zinc_N_2 PF13602.6 OEU08088.1 - 0.14 13.2 0.0 0.28 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-MYND PF01753.18 OEU08089.1 - 5.7e-06 26.3 8.0 5.7e-06 26.3 8.0 1.8 2 0 0 2 2 2 1 MYND finger PEP_mutase PF13714.6 OEU08089.1 - 0.023 14.2 0.6 0.032 13.7 0.6 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase NAM-associated PF14303.6 OEU08089.1 - 0.11 13.2 0.9 0.16 12.7 0.9 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TPPII_N PF12583.8 OEU08089.1 - 0.28 11.7 4.9 0.46 11.1 4.9 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal FAM199X PF15814.5 OEU08089.1 - 0.67 8.9 3.5 0.98 8.4 3.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X Glyoxalase PF00903.25 OEU08090.1 - 1.4e-08 35.0 0.0 2.6e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OEU08090.1 - 0.0014 18.5 0.0 0.0038 17.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OEU08090.1 - 0.0022 18.1 0.0 0.11 12.6 0.0 2.2 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OEU08090.1 - 0.045 14.5 0.0 0.066 14.0 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain HA PF03457.14 OEU08095.1 - 1.3e-55 185.6 2.7 2.7e-17 62.9 0.0 3.1 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU08095.1 - 0.00055 20.0 0.5 4 7.6 0.0 3.3 3 0 0 3 3 3 2 Transcriptional regulation of mitochondrial recombination mRNA_cap_C PF03919.15 OEU08095.1 - 0.0061 17.2 1.6 0.2 12.3 0.1 2.5 1 1 2 3 3 3 1 mRNA capping enzyme, C-terminal domain DUF4817 PF16087.5 OEU08095.1 - 0.079 12.8 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DUF1987 PF09345.10 OEU08095.1 - 0.17 11.6 2.0 8.8 6.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1987) Beta_propel PF09826.9 OEU08096.1 - 0.0001 21.3 0.2 0.00075 18.5 0.1 2.1 2 0 0 2 2 2 1 Beta propeller domain LVIVD PF08309.11 OEU08096.1 - 0.018 14.3 0.0 11 5.4 0.0 3.5 3 0 0 3 3 3 0 LVIVD repeat Calcipressin PF04847.12 OEU08096.1 - 0.019 14.7 0.3 0.05 13.3 0.3 1.7 1 0 0 1 1 1 0 Calcipressin Mito_fiss_reg PF05308.11 OEU08096.1 - 0.046 13.8 5.9 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4106 PF13388.6 OEU08096.1 - 0.32 10.2 4.2 0.57 9.4 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SprA-related PF12118.8 OEU08097.1 - 0.045 12.9 8.8 0.053 12.7 8.8 1.0 1 0 0 1 1 1 0 SprA-related family Ribosomal_60s PF00428.19 OEU08097.1 - 0.051 14.2 2.9 0.077 13.6 2.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Chorion_2 PF03964.15 OEU08097.1 - 0.39 11.6 4.4 0.68 10.8 4.4 1.5 1 0 0 1 1 1 0 Chorion family 2 Presenilin PF01080.17 OEU08097.1 - 0.98 8.1 3.8 1.1 8.0 3.8 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 OEU08097.1 - 1.2 7.8 7.0 1.4 7.6 7.0 1.0 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.13 OEU08097.1 - 1.6 7.5 9.1 1.9 7.2 9.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PseudoU_synth_2 PF00849.22 OEU08098.1 - 8.1e-23 81.3 0.3 3e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF4245 PF14030.6 OEU08099.1 - 0.037 14.0 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) BTB_2 PF02214.22 OEU08100.1 - 5.4e-05 23.5 0.0 0.00022 21.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain PNPase_C PF12111.8 OEU08100.1 - 0.098 12.1 0.8 0.17 11.3 0.8 1.4 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal DUF1385 PF07136.11 OEU08101.1 - 0.062 12.6 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) HA PF03457.14 OEU08102.1 - 2.3e-26 91.9 0.5 8.2e-15 54.9 0.1 2.1 2 0 0 2 2 2 2 Helicase associated domain Yos9_DD PF17880.1 OEU08103.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain CnrY PF17524.2 OEU08104.1 - 0.049 13.8 1.3 0.2 11.9 1.3 2.0 1 0 0 1 1 1 0 Anti-sigma factor CnrY U1snRNP70_N PF12220.8 OEU08105.1 - 0.14 12.8 0.2 0.14 12.8 0.2 4.3 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal GAGA_bind PF06217.12 OEU08105.1 - 1.2 9.4 31.2 0.19 12.0 7.4 3.3 3 0 0 3 3 3 0 GAGA binding protein-like family zf-RING_2 PF13639.6 OEU08106.1 - 9.9e-05 22.6 12.7 0.0086 16.4 4.6 2.6 2 0 0 2 2 2 2 Ring finger domain zf-ANAPC11 PF12861.7 OEU08106.1 - 0.00098 19.1 2.5 0.00098 19.1 2.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OEU08106.1 - 0.0024 18.1 3.2 0.0024 18.1 3.2 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain HemY_N PF07219.13 OEU08106.1 - 0.02 15.1 0.2 0.081 13.1 0.2 2.0 2 0 0 2 2 2 0 HemY protein N-terminus zinc_ribbon_9 PF14369.6 OEU08106.1 - 0.048 13.9 2.0 1.7 9.0 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-C3HC4_2 PF13923.6 OEU08106.1 - 2.6 8.0 12.3 6.3 6.7 1.4 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OEU08106.1 - 3.1 8.0 8.7 0.37 11.0 1.7 2.5 2 0 0 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 OEU08106.1 - 6.7 6.6 9.6 1.1 9.1 1.6 2.8 2 0 0 2 2 2 0 RING-like zinc finger MutS_V PF00488.21 OEU08107.1 - 3.1e-70 236.1 0.0 5e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 OEU08107.1 - 2e-30 105.4 0.1 3.9e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 OEU08107.1 - 2.2e-27 96.6 0.0 4.4e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 OEU08107.1 - 0.00074 19.8 0.0 0.0037 17.6 0.0 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OEU08107.1 - 0.033 14.5 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 MutS family domain IV DUF2097 PF09870.9 OEU08107.1 - 0.034 14.3 0.3 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2097) Bd3614-deam PF14439.6 OEU08108.1 - 0.22 11.6 1.8 0.33 11.0 1.8 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase AID PF18767.1 OEU08109.1 - 0.062 13.3 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Activation induced deaminase Fis1_TPR_C PF14853.6 OEU08112.1 - 0.002 18.1 0.1 0.0058 16.7 0.1 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat DUF4201 PF13870.6 OEU08112.1 - 0.34 10.6 6.7 0.09 12.5 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FAD_binding_4 PF01565.23 OEU08113.1 - 8.3e-24 83.9 3.1 1.8e-23 82.8 3.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OEU08113.1 - 0.048 13.8 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like DUF2870 PF11069.8 OEU08114.1 - 0.039 14.3 0.4 0.13 12.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2120 PF09893.9 OEU08114.1 - 0.52 10.4 4.8 18 5.4 2.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) HA PF03457.14 OEU08115.1 - 1e-53 179.5 6.0 1.2e-17 63.9 0.2 3.1 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU08115.1 - 0.00022 21.2 0.1 9 6.5 0.0 3.7 4 0 0 4 4 4 3 Transcriptional regulation of mitochondrial recombination DUF3822 PF12864.7 OEU08115.1 - 0.011 15.0 1.9 7.4 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3822) PMR5N PF14416.6 OEU08115.1 - 0.011 16.0 0.4 48 4.4 0.0 3.6 3 0 0 3 3 3 0 PMR5 N terminal Domain PHINT_rpt PF14882.6 OEU08115.1 - 2.6 8.4 15.1 47 4.4 0.3 5.7 6 0 0 6 6 6 0 Phage-integrase repeat unit MATH PF00917.26 OEU08117.1 - 0.073 13.2 10.6 0.077 13.2 0.9 3.8 3 1 0 3 3 3 0 MATH domain DUF4578 PF15147.6 OEU08117.1 - 4.3 8.2 9.8 3.1 8.7 6.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4578) DnaJ PF00226.31 OEU08119.1 - 5.8e-06 26.3 1.7 6.6e-06 26.2 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain Cnn_1N PF07989.11 OEU08119.1 - 0.055 13.6 7.4 0.18 12.0 7.4 1.9 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 CNOT11 PF10155.9 OEU08119.1 - 0.067 13.4 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 CdiA_C_tRNase PF18664.1 OEU08119.1 - 0.24 11.6 3.2 0.24 11.6 1.6 1.8 1 1 0 1 1 1 0 CdiA C-terminal tRNase domain DUF4094 PF13334.6 OEU08119.1 - 0.38 11.2 6.0 3.4 8.1 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TMF_DNA_bd PF12329.8 OEU08119.1 - 1.8 8.6 9.8 4.6 7.3 9.8 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3552 PF12072.8 OEU08119.1 - 5.6 6.3 10.3 9.9 5.5 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Uso1_p115_C PF04871.13 OEU08119.1 - 9.4 6.6 18.3 1.4 9.3 10.2 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2314 PF10077.9 OEU08122.1 - 0.083 13.0 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) Stc1 PF12898.7 OEU08124.1 - 0.0011 19.4 10.9 0.0011 19.4 10.9 2.1 2 0 0 2 2 2 1 Stc1 domain Carboxyl_trans PF01039.22 OEU08126.1 - 2.9e-152 507.8 0.0 4.3e-152 507.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 OEU08126.1 - 8.3e-123 411.1 0.0 1.2e-122 410.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 OEU08126.1 - 4.4e-50 170.1 0.0 8.9e-50 169.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OEU08126.1 - 3e-25 88.9 0.0 6.9e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OEU08126.1 - 1e-20 73.8 0.0 2.8e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OEU08126.1 - 5.1e-10 39.0 1.4 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OEU08126.1 - 0.0073 16.1 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 OEU08126.1 - 0.009 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 OEU08126.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain HA PF03457.14 OEU08127.1 - 3e-31 107.5 3.9 1.2e-16 60.7 0.6 2.2 2 0 0 2 2 2 2 Helicase associated domain Mei5_like PF17021.5 OEU08127.1 - 0.0085 16.1 2.4 0.44 10.6 0.1 2.3 2 0 0 2 2 2 2 Putative double-strand recombination repair-like DUF4116 PF13475.6 OEU08128.1 - 1.1e-51 172.3 0.3 8.9e-14 51.0 0.0 4.2 2 1 3 5 5 5 5 Domain of unknown function (DUF4116) Sen15 PF09631.10 OEU08128.1 - 0.0064 16.8 2.1 1.1 9.6 1.1 3.9 1 1 2 3 3 3 1 Sen15 protein DUF1667 PF07892.11 OEU08128.1 - 0.072 13.1 0.0 8.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) PRORP PF16953.5 OEU08128.1 - 0.2 11.1 1.2 1.3 8.5 0.1 2.0 1 1 1 2 2 2 0 Protein-only RNase P Beta-APP PF03494.13 OEU08128.1 - 0.87 9.5 5.8 59 3.6 0.1 4.6 5 0 0 5 5 5 0 Beta-amyloid peptide (beta-APP) TMEM220 PF15071.6 OEU08129.1 - 5e-11 43.3 1.1 9.4e-11 42.4 0.2 1.9 2 1 0 2 2 2 1 Transmembrane family 220, helix CTXphi_pIII-N1 PF16710.5 OEU08129.1 - 0.077 13.1 1.3 0.84 9.8 0.1 2.4 1 1 1 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII DUF3671 PF12420.8 OEU08129.1 - 0.28 11.3 5.9 0.77 9.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function Pox_EPC_I2-L1 PF12575.8 OEU08129.1 - 0.4 10.9 2.7 1.8 8.9 0.4 2.5 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 LRR_4 PF12799.7 OEU08130.1 - 1.4e-18 66.6 46.6 0.0011 19.4 0.8 7.4 1 1 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU08130.1 - 3.5e-18 65.1 43.6 3.1e-05 23.7 2.5 5.6 3 1 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 OEU08130.1 - 0.0073 16.7 27.6 0.3 11.8 0.1 9.1 8 3 1 9 9 9 2 Leucine Rich Repeat TNV_CP PF03898.13 OEU08130.1 - 0.041 13.2 0.4 11 5.2 0.0 3.2 2 1 1 3 3 3 0 Satellite tobacco necrosis virus coat protein PM0188 PF11477.8 OEU08130.1 - 1.6 7.8 4.7 24 4.0 0.0 4.0 2 2 2 5 5 5 0 Sialyltransferase PMO188 Antimicrobial_4 PF08024.11 OEU08130.1 - 2.3 8.4 6.7 29 4.9 0.1 5.5 10 0 0 10 10 10 0 Ant antimicrobial peptide LRR_9 PF14580.6 OEU08130.1 - 3.4 7.2 9.4 11 5.5 0.2 3.2 1 1 2 3 3 3 0 Leucine-rich repeat Cyclin_N PF00134.23 OEU08131.1 - 1.4e-10 41.0 0.1 2.9e-10 40.0 0.1 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain MnmE_helical PF12631.7 OEU08132.1 - 0.014 15.6 1.7 0.022 14.9 1.7 1.3 1 0 0 1 1 1 0 MnmE helical domain Retrotran_gag_2 PF14223.6 OEU08132.1 - 0.043 13.5 7.9 0.056 13.1 0.2 2.8 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type BLOC1_2 PF10046.9 OEU08132.1 - 0.18 12.1 8.1 0.22 11.8 2.6 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 eIF3_N PF09440.10 OEU08132.1 - 1.8 9.0 9.5 10 6.6 3.3 2.6 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF1104 PF06518.11 OEU08132.1 - 5.5 7.4 12.8 4.3 7.8 4.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) GrlR PF16518.5 OEU08136.1 - 0.052 13.5 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 T3SS negative regulator,GrlR CBP_BcsR PF10945.8 OEU08136.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Peptidase_M24 PF00557.24 OEU08138.1 - 4.6e-37 127.7 0.0 6.4e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 OEU08138.1 - 0.02 15.0 3.9 0.029 14.5 3.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OEU08138.1 - 0.032 12.5 1.0 0.032 12.5 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 OEU08138.1 - 1.5 8.1 11.8 1.9 7.8 11.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Drc1-Sld2 PF11719.8 OEU08138.1 - 5 6.6 7.9 6.4 6.2 7.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 OEU08138.1 - 5.2 5.2 10.8 6.6 4.8 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 OEU08138.1 - 5.7 7.0 14.1 9.3 6.3 14.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Endosulfine PF04667.17 OEU08141.1 - 0.00011 22.3 0.1 17 5.7 0.0 4.1 1 1 3 4 4 4 2 cAMP-regulated phosphoprotein/endosulfine conserved region Med2 PF11214.8 OEU08141.1 - 0.014 15.5 1.3 45 4.3 0.0 4.0 1 1 3 4 4 4 0 Mediator complex subunit 2 P3A PF08727.11 OEU08141.1 - 0.036 13.4 3.2 17 4.9 0.1 3.8 1 1 3 4 4 4 0 Poliovirus 3A protein like Period_C PF12114.8 OEU08141.1 - 0.17 11.5 5.6 1.3 8.6 2.0 2.2 1 1 1 2 2 2 0 Period protein 2/3C-terminal region Thyroglobulin_1 PF00086.18 OEU08141.1 - 0.24 11.1 3.8 54 3.6 0.0 3.7 2 1 1 4 4 4 0 Thyroglobulin type-1 repeat Plant_all_beta PF10532.9 OEU08141.1 - 0.64 10.3 9.6 34 4.7 0.1 4.0 1 1 3 4 4 4 0 Plant specific N-all beta domain PH_10 PF15411.6 OEU08144.1 - 0.01 16.1 0.6 0.023 14.9 0.2 1.7 1 1 1 2 2 2 0 Pleckstrin homology domain BRCC36_C PF18110.1 OEU08144.1 - 0.029 14.5 0.2 0.029 14.5 0.2 1.7 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain GPI2 PF06432.11 OEU08144.1 - 0.12 11.8 4.4 0.68 9.3 0.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Jiraiya PF15038.6 OEU08144.1 - 0.18 11.2 8.4 0.13 11.7 6.7 1.7 2 1 0 2 2 2 0 Jiraiya Ribosomal_L36e PF01158.18 OEU08145.1 - 0.0002 21.5 0.3 0.0002 21.5 0.3 6.2 5 1 2 7 7 7 1 Ribosomal protein L36e CRA PF06589.11 OEU08146.1 - 1.2 9.3 8.7 0.39 10.8 1.6 2.4 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) CDC37_C PF08564.10 OEU08147.1 - 0.079 13.1 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Cdc37 C terminal domain DUF2065 PF09838.9 OEU08147.1 - 0.28 11.2 2.2 10 6.2 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) Phage_Coat_B PF05356.11 OEU08147.1 - 0.93 9.4 3.8 0.43 10.5 0.3 2.2 2 2 0 2 2 2 0 Phage Coat protein B CD20 PF04103.15 OEU08147.1 - 5.8 7.0 7.5 1.8 8.6 0.9 2.6 2 1 2 4 4 4 0 CD20-like family Aa_trans PF01490.18 OEU08148.1 - 1.6e-28 99.6 22.2 1.9e-28 99.4 22.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_PAP PF03325.13 OEU08150.1 - 0.038 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein HAUS6_N PF14661.6 OEU08150.1 - 0.19 11.3 4.2 0.29 10.7 4.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Chloroa_b-bind PF00504.21 OEU08151.1 - 5.6e-32 111.5 0.2 7.4e-32 111.1 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Lipoprotein_2 PF00921.17 OEU08152.1 - 6.3 6.3 13.8 13 5.2 13.0 2.0 1 1 0 1 1 1 0 Borrelia lipoprotein HMG_box PF00505.19 OEU08155.1 - 1.5e-09 38.1 0.5 1.1e-07 32.2 0.5 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU08155.1 - 5.1e-07 30.2 0.1 1.1e-06 29.1 0.1 1.5 1 1 0 1 1 1 1 HMG-box domain YABBY PF04690.13 OEU08155.1 - 0.01 16.4 0.1 0.01 16.4 0.1 1.2 1 0 0 1 1 1 0 YABBY protein Barttin PF15462.6 OEU08161.1 - 3.1 7.5 10.1 0.14 11.9 3.5 1.8 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) GSDH PF07995.11 OEU08164.1 - 1.5e-23 83.6 4.6 6.1e-23 81.6 4.5 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU08164.1 - 3.7e-10 39.5 0.2 1.5e-09 37.6 0.2 2.1 1 0 0 1 1 1 1 PKD domain Sarcoglycan_2 PF05510.13 OEU08164.1 - 0.024 13.4 0.1 0.042 12.6 0.1 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TMEM132D_C PF15706.5 OEU08164.1 - 0.068 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4999 PF16390.5 OEU08164.1 - 0.12 12.6 0.6 0.58 10.4 0.6 2.2 1 0 0 1 1 1 0 Domain of unknown function EphA2_TM PF14575.6 OEU08164.1 - 0.26 12.2 4.4 0.33 11.8 0.0 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_4 PF12799.7 OEU08165.1 - 7e-18 64.4 6.7 3.3e-05 24.1 0.1 4.2 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU08165.1 - 4.4e-13 48.8 10.2 5.3e-06 26.1 0.1 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 OEU08165.1 - 1.5e-07 31.0 3.4 12 6.9 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat DUF3338 PF11819.8 OEU08165.1 - 0.14 12.1 0.5 29 4.6 0.0 4.1 3 2 3 6 6 6 0 Domain of unknown function (DUF3338) Romo1 PF10247.9 OEU08166.1 - 0.091 13.1 13.8 0.33 11.3 8.6 2.4 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Yae1_N PF09811.9 OEU08167.1 - 5.9e-05 22.7 38.7 1.3 8.8 0.1 12.5 7 6 6 13 13 13 3 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU08167.1 - 0.021 14.8 1.2 0.021 14.8 1.2 6.4 3 1 1 4 4 4 0 Glycine zipper DUF3084 PF11283.8 OEU08167.1 - 0.026 14.5 6.0 36 4.4 0.0 5.2 4 2 1 5 5 5 0 Protein of unknown function (DUF3084) DUF3789 PF12664.7 OEU08167.1 - 7.4 6.4 10.6 8 6.3 0.0 5.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3789) Fasciclin PF02469.22 OEU08168.1 - 3.7e-52 175.9 6.1 1e-22 80.7 0.0 3.3 3 0 0 3 3 3 3 Fasciclin domain Fasciclin PF02469.22 OEU08169.1 - 4.9e-63 211.1 3.9 2.3e-22 79.6 0.0 4.2 4 0 0 4 4 4 4 Fasciclin domain HTH_53 PF18606.1 OEU08169.1 - 0.037 13.7 0.0 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain LCD1 PF09798.9 OEU08169.1 - 0.039 12.5 0.0 4.6 5.6 0.0 2.1 2 0 0 2 2 2 0 DNA damage checkpoint protein Fasciclin PF02469.22 OEU08170.1 - 1.2e-27 96.6 0.0 1.3e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Nop14 PF04147.12 OEU08171.1 - 3.2e-06 25.7 21.2 4.2e-06 25.3 21.2 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OEU08171.1 - 1.7e-05 24.4 24.0 2.3e-05 24.0 24.0 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 OEU08171.1 - 0.00076 18.9 21.6 0.0011 18.3 21.6 1.4 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 OEU08171.1 - 0.00091 17.7 25.3 0.0012 17.3 25.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Utp14 PF04615.13 OEU08171.1 - 0.001 17.8 18.4 0.0018 16.9 18.4 1.5 1 0 0 1 1 1 1 Utp14 protein Cwf_Cwc_15 PF04889.12 OEU08171.1 - 0.0015 18.4 35.5 0.003 17.3 32.9 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 OEU08171.1 - 0.0043 16.3 32.4 0.0067 15.6 32.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop53 PF07767.11 OEU08171.1 - 0.0069 15.8 22.6 0.0069 15.8 22.6 1.4 2 0 0 2 2 1 1 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 OEU08171.1 - 0.0096 15.9 34.2 0.0096 15.9 34.2 1.7 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 OEU08171.1 - 0.013 13.7 34.5 0.019 13.1 34.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 OEU08171.1 - 0.062 13.2 21.6 0.13 12.1 19.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Drc1-Sld2 PF11719.8 OEU08171.1 - 0.13 11.8 22.3 0.061 12.9 20.3 1.5 2 0 0 2 2 1 0 DNA replication and checkpoint protein CDC27 PF09507.10 OEU08171.1 - 0.15 11.4 26.0 0.14 11.5 24.6 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF262 PF03235.14 OEU08171.1 - 0.38 10.9 11.7 0.18 11.9 9.2 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF262 RR_TM4-6 PF06459.12 OEU08171.1 - 0.43 10.4 14.8 0.69 9.7 14.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 OEU08171.1 - 0.45 10.6 44.3 0.56 10.3 44.3 1.4 1 1 0 1 1 1 0 YL1 nuclear protein FAM220 PF15487.6 OEU08171.1 - 0.59 9.7 9.5 0.83 9.2 9.5 1.3 1 0 0 1 1 1 0 FAM220 family TFIIF_alpha PF05793.12 OEU08171.1 - 0.64 8.6 32.4 0.92 8.0 32.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PTPRCAP PF15713.5 OEU08171.1 - 0.68 10.2 21.4 1.2 9.5 21.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Zip PF02535.22 OEU08171.1 - 1.1 8.4 4.1 1.4 8.1 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Roughex PF06020.11 OEU08171.1 - 1.2 8.2 12.5 1.5 7.8 12.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 OEU08171.1 - 1.5 8.8 4.9 2.3 8.2 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3381 PF11861.8 OEU08171.1 - 1.9 8.3 28.5 1.6 8.5 24.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Gti1_Pac2 PF09729.9 OEU08171.1 - 2.2 8.4 10.3 4.1 7.5 10.3 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Presenilin PF01080.17 OEU08171.1 - 2.3 6.9 11.4 2.8 6.6 11.4 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 OEU08171.1 - 2.3 7.1 9.4 3.2 6.7 9.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 OEU08171.1 - 3.1 6.7 14.7 4.6 6.2 14.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RRN3 PF05327.11 OEU08171.1 - 5 5.6 23.4 6.6 5.1 23.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IFT57 PF10498.9 OEU08171.1 - 5.9 5.7 20.7 9.8 5.0 20.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NAM-associated PF14303.6 OEU08171.1 - 7.2 7.3 23.2 1.2 9.8 19.6 1.5 2 0 0 2 2 1 0 No apical meristem-associated C-terminal domain Methyltransf_11 PF08241.12 OEU08172.1 - 8e-13 48.9 0.1 2.6e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU08172.1 - 3.9e-08 33.9 0.1 2.2e-07 31.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU08172.1 - 6.9e-07 29.2 0.0 9.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU08172.1 - 2.5e-06 27.0 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU08172.1 - 4.1e-05 24.2 0.0 7.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU08172.1 - 0.00032 20.6 0.0 0.00054 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU08172.1 - 0.0032 17.4 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Pox_Rap94 PF03294.14 OEU08172.1 - 0.14 10.3 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 DUF3494 PF11999.8 OEU08176.1 - 1.5e-56 191.3 17.4 1.8e-56 191.1 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Bactofilin PF04519.13 OEU08176.1 - 0.0006 20.1 3.3 0.47 10.8 1.0 2.5 2 1 0 2 2 2 2 Polymer-forming cytoskeletal Transposase_23 PF03017.14 OEU08176.1 - 0.011 15.7 0.2 0.029 14.3 0.1 1.8 2 0 0 2 2 2 0 TNP1/EN/SPM transposase DUF1285 PF06938.11 OEU08177.1 - 0.03 14.4 0.1 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) DUF2173 PF09941.9 OEU08177.1 - 0.058 13.7 0.3 0.79 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2173) TPR_12 PF13424.6 OEU08178.1 - 3.4e-48 161.8 11.8 7.5e-16 58.2 0.0 6.0 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 OEU08178.1 - 1.8e-47 157.9 14.9 6.3e-10 38.6 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 OEU08178.1 - 7.1e-31 104.8 12.5 2.7e-05 23.8 0.3 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08178.1 - 1e-27 94.0 18.2 7.7e-05 22.5 0.3 7.7 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 OEU08178.1 - 1.2e-25 87.5 14.3 0.00011 22.1 0.1 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU08178.1 - 4.8e-21 75.5 1.9 7.6e-12 45.2 0.3 3.7 2 1 2 4 4 4 2 MalT-like TPR region TPR_11 PF13414.6 OEU08178.1 - 2.5e-17 62.3 9.2 0.00036 20.1 0.1 7.3 6 1 1 7 7 7 4 TPR repeat TPR_14 PF13428.6 OEU08178.1 - 7.8e-16 57.4 7.2 0.42 11.6 0.0 7.7 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU08178.1 - 1.7e-15 55.8 14.7 0.00087 19.2 0.1 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 OEU08178.1 - 3.6e-12 46.7 5.7 0.0022 18.6 0.0 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU08178.1 - 7.8e-09 35.9 1.7 0.01 16.3 0.1 4.8 4 2 2 6 6 5 3 Tetratricopeptide repeat SNAP PF14938.6 OEU08178.1 - 3.9e-07 29.8 5.9 0.0042 16.6 0.0 4.5 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OEU08178.1 - 4e-07 30.3 12.5 3.1 8.6 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU08178.1 - 2.5e-06 27.5 0.1 37 5.0 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 OEU08178.1 - 2.1e-05 24.3 6.7 0.24 11.1 0.1 4.7 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_4 PF07721.14 OEU08178.1 - 4.3e-05 23.7 0.2 12 6.9 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 OEU08178.1 - 4.9e-05 23.3 0.4 6.4 7.3 0.0 5.5 5 1 1 6 6 6 1 PPR repeat DUF2225 PF09986.9 OEU08178.1 - 0.00046 20.0 0.6 1.1 8.9 0.1 3.4 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_15 PF13429.6 OEU08178.1 - 0.00073 18.8 5.5 1.1 8.4 0.1 4.9 2 2 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU08178.1 - 0.0011 19.2 8.0 10 6.4 0.1 5.5 2 1 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 OEU08178.1 - 0.0019 18.2 9.3 2.2 8.4 0.1 6.5 7 1 1 8 8 7 1 MIT (microtubule interacting and transport) domain PPR_2 PF13041.6 OEU08178.1 - 0.015 15.5 0.6 15 5.8 0.0 4.2 4 0 0 4 4 4 0 PPR repeat family TPR_21 PF09976.9 OEU08178.1 - 0.033 13.9 9.2 0.038 13.7 0.4 4.4 4 3 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF4810 PF16068.5 OEU08178.1 - 0.12 12.9 6.2 5.4 7.6 0.1 4.5 5 1 0 5 5 3 0 Domain of unknown function (DUF4810) Macoilin PF09726.9 OEU08178.1 - 0.35 9.4 6.2 0.48 8.9 6.2 1.2 1 0 0 1 1 1 0 Macoilin family BTAD PF03704.17 OEU08178.1 - 0.48 10.8 9.6 8 6.9 0.2 4.8 4 1 0 5 5 5 0 Bacterial transcriptional activator domain FA_FANCE PF11510.8 OEU08179.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE GrpE PF01025.19 OEU08180.1 - 4.4e-41 140.3 0.5 5.6e-41 140.0 0.5 1.1 1 0 0 1 1 1 1 GrpE RisS_PPD PF16524.5 OEU08180.1 - 0.00029 21.1 0.1 0.34 11.2 0.2 2.1 1 1 0 2 2 2 2 Periplasmic domain of Sensor histidine kinase RisS DUF383 PF04063.14 OEU08181.1 - 0.024 14.3 0.0 0.024 14.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DUF384 PF04064.13 OEU08182.1 - 8.5e-07 28.7 0.1 8.5e-07 28.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DNA_pol_A_exo1 PF01612.20 OEU08184.1 - 1.8e-20 73.4 0.3 2.5e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 3'-5' exonuclease KH_1 PF00013.29 OEU08184.1 - 0.00099 18.9 0.1 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 OEU08184.1 - 0.0044 16.8 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 KH domain Exo84_C PF16528.5 OEU08184.1 - 0.034 14.0 0.1 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 Exocyst component 84 C-terminal CitT PF12431.8 OEU08184.1 - 0.17 12.3 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PTP_N PF12453.8 OEU08185.1 - 0.043 13.5 0.2 72 3.2 0.0 3.6 3 0 0 3 3 3 0 Protein tyrosine phosphatase N terminal Prp18 PF02840.15 OEU08186.1 - 0.83 9.7 7.3 0.4 10.7 3.7 2.2 2 0 0 2 2 2 0 Prp18 domain CENP-R PF06729.12 OEU08186.1 - 9 6.2 14.7 0.31 11.0 0.4 3.5 4 0 0 4 4 4 0 Kinetochore component, CENP-R Spore_YhcN_YlaJ PF09580.10 OEU08186.1 - 9.1 6.3 21.1 4.1e+03 -2.3 21.1 2.6 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF2358 PF10184.9 OEU08188.1 - 0.025 14.9 0.2 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) SR-25 PF10500.9 OEU08188.1 - 0.051 13.2 4.2 0.083 12.5 4.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NifU PF01106.17 OEU08188.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 NifU-like domain BIRC6 PF12356.8 OEU08188.1 - 2 7.8 7.8 0.52 9.7 2.5 2.1 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Cupin_1 PF00190.22 OEU08189.1 - 4.3e-24 84.8 0.1 7.3e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OEU08189.1 - 1.6e-13 50.2 0.0 0.0015 18.2 0.0 3.3 3 0 0 3 3 3 3 Cupin domain WW_like PF17890.1 OEU08189.1 - 0.00013 21.9 0.1 0.032 14.3 0.0 2.6 2 0 0 2 2 2 2 Peptidoglycan hydrolase LytB WW-like domain RicinB_lectin_2 PF14200.6 OEU08189.1 - 0.07 13.9 0.3 0.68 10.7 0.0 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like SUIM_assoc PF16619.5 OEU08190.1 - 0.014 15.4 2.8 0.044 13.8 2.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4805 PF16063.5 OEU08190.1 - 3.1 7.1 14.4 0.19 11.1 3.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4805) Fasciclin PF02469.22 OEU08192.1 - 4.1e-21 75.5 0.0 7.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU08192.1 - 0.00015 22.5 0.8 0.0026 18.5 0.8 2.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ABC_membrane_2 PF06472.15 OEU08192.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 DUF3458_C PF17432.2 OEU08193.1 - 2.6e-95 319.5 0.0 4.2e-95 318.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 OEU08193.1 - 9e-53 179.1 1.0 1.4e-52 178.4 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 OEU08193.1 - 1.1e-23 83.4 0.0 2.3e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 OEU08193.1 - 4e-10 40.2 0.0 8.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 OEU08193.1 - 0.13 12.7 0.5 0.54 10.7 0.5 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase RP-C_C PF11800.8 OEU08195.1 - 0.01 15.9 0.5 0.01 15.9 0.5 2.1 3 0 0 3 3 3 0 Replication protein C C-terminal region Methyltransf_12 PF08242.12 OEU08195.1 - 7.2 7.4 5.8 14 6.5 0.1 3.0 3 1 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 OEU08196.1 - 2.8e-14 53.1 0.1 3.4e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08196.1 - 4.7e-13 49.0 0.2 7.4e-13 48.4 0.2 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Thiol_cytolys_C PF17440.2 OEU08198.1 - 0.056 13.6 1.1 0.098 12.8 1.1 1.4 1 0 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain PBP1_TM PF14812.6 OEU08198.1 - 0.85 10.0 11.1 4.4 7.7 1.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4337 PF14235.6 OEU08198.1 - 8.3 6.5 7.4 2 8.5 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Presenilin PF01080.17 OEU08198.1 - 8.3 5.0 7.9 9.7 4.8 7.9 1.2 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 OEU08199.1 - 7.7e-07 28.8 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OEU08199.1 - 0.0011 18.8 0.0 0.0073 16.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase-like cPLA2_C2 PF18695.1 OEU08200.1 - 0.0031 17.5 0.6 0.008 16.1 0.6 1.6 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain DDE_Tnp_4 PF13359.6 OEU08202.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease MFAP1 PF06991.11 OEU08204.1 - 0.0033 17.3 0.4 0.0044 16.9 0.4 1.1 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing DUF4064 PF13273.6 OEU08205.1 - 4.5e-06 26.9 1.4 0.082 13.2 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF4064) DUF5504 PF17608.2 OEU08205.1 - 0.045 13.8 17.1 0.027 14.5 3.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5504) Suf PF05843.14 OEU08205.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.2 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) Git3 PF11710.8 OEU08205.1 - 0.25 11.1 11.8 0.02 14.7 4.4 2.4 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 NdhL PF10716.9 OEU08205.1 - 1.2 9.1 5.4 2.8 8.0 0.0 3.4 4 0 0 4 4 4 0 NADH dehydrogenase transmembrane subunit DivIC PF04977.15 OEU08205.1 - 8.9 6.2 7.7 1.4 8.7 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator Defensin_1 PF00323.19 OEU08206.1 - 0.0073 16.9 2.6 0.0092 16.5 0.3 2.5 2 0 0 2 2 2 1 Mammalian defensin Dicty_CAD PF05720.12 OEU08207.1 - 0.096 12.7 0.9 9.5 6.3 0.1 2.8 2 0 0 2 2 2 0 Cell-cell adhesion domain Desulfoferrod_N PF06397.12 OEU08207.1 - 0.098 12.3 7.1 18 5.0 0.2 3.5 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_15 PF17032.5 OEU08207.1 - 0.35 11.6 7.5 43 5.0 0.1 4.2 5 0 0 5 5 5 0 zinc-ribbon family DUF2175 PF09943.9 OEU08207.1 - 0.52 10.6 4.4 54 4.2 0.2 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) ABC_membrane_2 PF06472.15 OEU08212.1 - 1.4e-38 132.9 6.4 2.6e-38 132.0 4.9 2.2 1 1 1 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OEU08212.1 - 2.1e-09 38.0 0.0 1.9e-08 34.9 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OEU08212.1 - 0.0012 19.2 0.1 0.0081 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TctB PF07331.11 OEU08212.1 - 0.0041 17.4 3.1 0.0041 17.4 3.1 2.4 3 0 0 3 3 3 1 Tripartite tricarboxylate transporter TctB family AAA PF00004.29 OEU08212.1 - 0.027 14.9 0.0 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OEU08212.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 OEU08212.1 - 0.056 13.2 0.1 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NAD_Gly3P_dh_C PF07479.14 OEU08212.1 - 0.066 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SelR PF01641.18 OEU08215.1 - 0.0067 16.5 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 SelR domain EphA2_TM PF14575.6 OEU08215.1 - 0.036 14.9 0.0 4.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 OEU08215.1 - 0.056 14.1 0.0 17 6.1 0.0 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red tRNA_anti-like PF12869.7 OEU08215.1 - 0.35 10.5 2.2 2.1 7.9 0.0 2.4 3 0 0 3 3 3 0 tRNA_anti-like SNF2_N PF00176.23 OEU08217.1 - 6.6e-15 54.7 0.0 5.9e-14 51.5 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OEU08217.1 - 5e-09 35.9 5.7 0.0009 18.7 0.0 3.5 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase CDC45 PF02724.14 OEU08217.1 - 0.0062 14.9 18.5 0.011 14.1 18.5 1.3 1 0 0 1 1 1 1 CDC45-like protein ResIII PF04851.15 OEU08217.1 - 0.1 12.6 0.0 0.1 12.6 0.0 3.3 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3246 PF11596.8 OEU08217.1 - 1.2 8.5 21.6 0.5 9.7 18.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF4604 PF15377.6 OEU08217.1 - 3.5 8.0 23.2 14 6.0 23.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RabGAP-TBC PF00566.18 OEU08218.1 - 2.1e-13 50.4 4.3 3.9e-11 43.0 0.1 2.9 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Dirigent PF03018.14 OEU08220.1 - 0.021 14.6 0.5 0.052 13.3 0.5 1.6 1 0 0 1 1 1 0 Dirigent-like protein Bcl-2_3 PF15286.6 OEU08221.1 - 0.013 16.1 0.1 0.024 15.3 0.1 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Pes-10 PF07149.11 OEU08221.1 - 0.025 13.7 2.9 0.034 13.2 2.9 1.2 1 0 0 1 1 1 0 Pes-10 DUF2315 PF10231.9 OEU08221.1 - 0.85 9.7 8.6 0.35 11.0 2.8 2.1 1 1 1 2 2 2 0 Apoptogenic protein 1 Dirigent PF03018.14 OEU08222.1 - 0.019 14.8 0.5 0.04 13.7 0.5 1.5 1 0 0 1 1 1 0 Dirigent-like protein Trypan_PARP PF05887.11 OEU08223.1 - 1.5 8.8 25.7 2.5 8.1 25.7 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPATA3 PF15662.5 OEU08223.1 - 1.9 9.1 14.0 2.2 8.9 14.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family RP-C_C PF11800.8 OEU08223.1 - 2.2 8.4 6.0 2.3 8.3 6.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Insulin_TMD PF17870.1 OEU08224.1 - 0.11 12.6 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RPW8 PF05659.11 OEU08224.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fasciclin PF02469.22 OEU08226.1 - 9e-21 74.4 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU08226.1 - 2.1e-05 25.3 0.0 0.00012 22.8 0.0 2.1 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Deltameth_res PF16020.5 OEU08227.1 - 0.045 13.6 1.5 11 6.0 0.2 2.7 2 0 0 2 2 2 0 Deltamethrin resistance DUF202 PF02656.15 OEU08227.1 - 2.9 8.4 7.2 19 5.8 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF1289 PF06945.13 OEU08228.1 - 0.19 11.5 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) TAF4 PF05236.14 OEU08228.1 - 2.6 7.7 19.8 0.21 11.3 7.4 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Methyltransf_23 PF13489.6 OEU08229.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF1336 PF07059.12 OEU08230.1 - 9.3e-43 146.9 0.0 1.4e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) P22_Tail-4 PF11650.8 OEU08230.1 - 0.035 14.0 0.2 0.78 9.7 0.1 2.4 2 0 0 2 2 2 0 P22 tail accessory factor Caldesmon PF02029.15 OEU08231.1 - 0.034 12.9 42.6 0.13 11.0 11.3 2.3 2 0 0 2 2 2 0 Caldesmon Pex2_Pex12 PF04757.14 OEU08231.1 - 4.5 6.8 4.8 0.89 9.1 0.4 1.9 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Utp14 PF04615.13 OEU08231.1 - 7.1 5.1 51.4 5.6 5.4 29.6 2.3 2 0 0 2 2 2 0 Utp14 protein Ank_2 PF12796.7 OEU08234.1 - 2.9e-05 24.6 0.0 3.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU08234.1 - 0.00018 22.0 0.0 0.0003 21.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU08234.1 - 0.017 15.5 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 OEU08234.1 - 0.021 15.3 0.0 0.74 10.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat FRG2 PF15315.6 OEU08235.1 - 0.39 10.9 7.0 0.92 9.7 7.0 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 NST1 PF13945.6 OEU08235.1 - 2.4 8.2 8.6 3.7 7.6 6.2 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF333 PF03891.15 OEU08236.1 - 0.014 15.6 0.4 0.043 14.0 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF333) PT PF04886.12 OEU08237.1 - 0.029 13.9 48.2 2.1 8.0 32.0 4.7 3 1 0 3 3 3 0 PT repeat CitX PF03802.14 OEU08238.1 - 0.046 13.5 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Histidinol_dh PF00815.20 OEU08239.1 - 3e-110 369.1 0.1 3.6e-110 368.8 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PPC PF04151.15 OEU08240.1 - 0.00025 22.1 1.1 0.00025 22.1 1.1 2.5 3 1 0 3 3 3 1 Bacterial pre-peptidase C-terminal domain PT PF04886.12 OEU08240.1 - 0.00028 20.4 53.6 1.8e+04 -9.0 53.6 3.1 1 1 0 1 1 1 0 PT repeat BES1_N PF05687.13 OEU08240.1 - 4.1 7.8 5.9 7.3 7.0 5.9 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal SPX PF03105.19 OEU08240.1 - 7.3 6.4 5.5 8.7 6.2 5.5 1.1 1 0 0 1 1 1 0 SPX domain GHMP_kinases_N PF00288.26 OEU08241.1 - 0.058 13.6 0.2 0.17 12.1 0.3 1.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain BTB_3 PF16017.5 OEU08241.1 - 0.12 12.5 0.3 6.4 6.9 0.1 2.4 2 0 0 2 2 2 0 BTB/POZ domain DUF3365 PF11845.8 OEU08241.1 - 0.95 9.8 12.1 1.8 8.8 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) Methyltr_RsmB-F PF01189.17 OEU08247.1 - 3.4e-27 95.4 0.4 7.6e-26 91.0 0.2 2.2 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Rtf2 PF04641.12 OEU08247.1 - 0.0076 15.6 6.5 0.07 12.5 1.3 2.3 2 0 0 2 2 2 2 Rtf2 RING-finger DUF3824 PF12868.7 OEU08247.1 - 0.29 11.8 7.6 0.32 11.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) NOA36 PF06524.12 OEU08247.1 - 0.76 9.0 8.1 1.7 7.9 8.1 1.6 1 0 0 1 1 1 0 NOA36 protein LCIB_C_CA PF18599.1 OEU08249.1 - 3.3e-65 219.5 0.0 3.8e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Methyltransf_21 PF05050.12 OEU08250.1 - 1.3e-12 48.1 3.2 1.9e-12 47.5 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase FkbM domain Met_10 PF02475.16 OEU08250.1 - 0.0021 17.9 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 OEU08250.1 - 0.0061 16.3 0.5 0.011 15.5 0.5 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) V_cholerae_RfbT PF05575.11 OEU08250.1 - 0.0064 15.8 0.4 0.27 10.5 0.1 2.4 3 0 0 3 3 3 1 Vibrio cholerae RfbT protein Sigma70_ner PF04546.13 OEU08250.1 - 0.092 12.6 9.5 0.15 11.9 8.3 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 OEU08250.1 - 0.11 10.6 24.1 0.026 12.7 20.7 1.6 2 0 0 2 2 2 0 DNA polymerase phi Ninjurin PF04923.12 OEU08250.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Ninjurin TFIIA PF03153.13 OEU08250.1 - 0.14 12.1 18.8 0.0095 16.0 10.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 OEU08250.1 - 0.49 10.6 23.6 2.3 8.4 23.6 2.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Trypan_PARP PF05887.11 OEU08250.1 - 1.9 8.5 11.3 4.8 7.2 11.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DPBB_1 PF03330.18 OEU08251.1 - 0.0016 18.7 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Isochorismatase PF00857.20 OEU08252.1 - 3.7e-11 43.5 0.6 7e-10 39.4 0.3 2.3 2 0 0 2 2 2 1 Isochorismatase family BLM10_mid PF16507.5 OEU08252.1 - 0.0031 16.3 0.2 0.012 14.3 0.0 1.8 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region Orf78 PF06024.12 OEU08252.1 - 0.012 15.9 0.5 0.012 15.9 0.5 2.8 3 0 0 3 3 3 0 Orf78 (ac78) NAD_binding_1 PF00175.21 OEU08252.1 - 0.081 13.6 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4710 PF15828.5 OEU08253.1 - 0.061 13.4 5.3 0.045 13.9 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Ribosomal_S8e PF01201.22 OEU08253.1 - 3.6 7.7 5.9 0.37 11.0 1.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S8e Yae1_N PF09811.9 OEU08254.1 - 0.043 13.5 31.9 8.3 6.2 0.3 10.2 6 5 2 8 8 8 0 Essential protein Yae1, N terminal MspA PF09203.11 OEU08254.1 - 0.29 11.0 8.2 6.6 6.6 1.3 3.5 1 1 1 2 2 2 0 MspA PT PF04886.12 OEU08255.1 - 2.3e-05 23.9 38.2 0.0041 16.6 5.7 4.9 2 1 1 3 3 3 3 PT repeat rve PF00665.26 OEU08256.1 - 1.7e-08 34.7 0.0 3.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DP-EP PF08985.11 OEU08257.1 - 0.019 15.1 0.2 0.03 14.5 0.2 1.4 1 1 0 1 1 1 0 DP-EP family Clathrin_propel PF01394.20 OEU08257.1 - 0.12 12.8 0.0 0.38 11.2 0.0 2.0 1 1 0 1 1 1 0 Clathrin propeller repeat DNA_pol_D_N PF18018.1 OEU08257.1 - 0.13 12.4 0.9 0.64 10.1 0.3 2.0 1 1 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain BCL9 PF11502.8 OEU08258.1 - 0.19 11.5 1.5 0.4 10.5 1.5 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein zf-MYND PF01753.18 OEU08258.1 - 0.21 11.7 5.9 0.2 11.7 2.7 2.2 2 0 0 2 2 2 0 MYND finger DUF443 PF04276.12 OEU08258.1 - 0.48 10.2 8.2 0.75 9.6 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Myb_DNA-binding PF00249.31 OEU08259.1 - 5.7e-16 58.4 0.1 3.7e-09 36.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU08259.1 - 6e-07 29.6 2.5 0.00017 21.7 0.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain FAM176 PF14851.6 OEU08259.1 - 0.81 9.4 3.4 6.5 6.4 1.5 2.2 2 0 0 2 2 2 0 FAM176 family DUF3159 PF11361.8 OEU08260.1 - 5.9e-06 26.2 2.6 8.3e-06 25.7 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3159) ER_lumen_recept PF00810.18 OEU08260.1 - 0.68 10.8 5.9 0.44 11.4 1.3 2.1 2 0 0 2 2 2 0 ER lumen protein retaining receptor SPC25 PF06703.11 OEU08260.1 - 0.78 9.5 6.4 0.099 12.4 0.8 2.0 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF202 PF02656.15 OEU08261.1 - 2.6e-10 40.6 0.9 1e-09 38.7 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PRP38_assoc PF12871.7 OEU08261.1 - 8.8 7.0 10.1 8.8 7.0 7.1 2.2 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Fasciclin PF02469.22 OEU08264.1 - 6.1e-09 36.2 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Fasciclin domain Stig1 PF04885.13 OEU08264.1 - 0.00065 20.2 6.1 0.0015 19.0 6.1 1.6 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Somatomedin_B PF01033.17 OEU08264.1 - 0.015 15.7 18.8 0.015 15.7 18.8 2.1 2 0 0 2 2 2 0 Somatomedin B domain SWI-SNF_Ssr4 PF08549.10 OEU08264.1 - 0.21 10.2 0.4 0.35 9.4 0.4 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Rdx PF10262.9 OEU08265.1 - 2.3e-14 53.3 0.1 4.4e-09 36.4 0.1 2.6 2 1 0 2 2 2 2 Rdx family PCB_OB PF17092.5 OEU08265.1 - 0.12 13.1 0.1 0.28 12.0 0.1 1.6 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain DUF4619 PF15398.6 OEU08265.1 - 0.8 9.2 8.1 0.11 12.0 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4619) NAD_binding_6 PF08030.12 OEU08266.1 - 2.4e-07 31.0 0.0 9.6e-07 29.0 0.0 2.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OEU08266.1 - 3.3e-06 27.1 0.0 7.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OEU08266.1 - 0.00016 21.8 6.9 0.00016 21.8 6.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component ArgoMid PF16487.5 OEU08267.1 - 0.044 14.0 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 Mid domain of argonaute Syntaxin_2 PF14523.6 OEU08267.1 - 6.8 7.1 16.8 0.57 10.6 2.0 3.1 2 1 2 4 4 4 0 Syntaxin-like protein DUF3800 PF12686.7 OEU08267.1 - 9.3 6.9 6.5 37 5.0 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DDE_Tnp_1_7 PF13843.6 OEU08268.1 - 2.7e-18 66.4 0.1 4.7e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Macscav_rec PF03523.13 OEU08269.1 - 0.079 12.9 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Macrophage scavenger receptor Glycos_transf_3 PF00591.21 OEU08270.1 - 1.3e-85 287.1 0.2 1.6e-85 286.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OEU08270.1 - 8.6e-17 60.7 0.0 2.6e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Lipase_GDSL_2 PF13472.6 OEU08271.1 - 2.4e-16 60.7 0.9 3.6e-16 60.1 0.9 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU08271.1 - 1.5e-08 34.9 3.2 4e-08 33.5 3.2 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 OEU08271.1 - 1.3e-06 28.3 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_3 PF14606.6 OEU08271.1 - 0.0022 18.2 0.4 0.39 10.8 0.1 2.3 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Methyltrn_RNA_2 PF04013.12 OEU08272.1 - 0.00041 20.1 0.1 0.0035 17.0 0.1 1.9 2 0 0 2 2 2 1 Putative SAM-dependent RNA methyltransferase NYAP_C PF15452.6 OEU08272.1 - 0.034 14.0 0.1 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter BSD PF03909.17 OEU08273.1 - 0.013 15.5 0.0 0.013 15.5 0.0 2.6 3 0 0 3 3 3 0 BSD domain 2OG-FeII_Oxy_3 PF13640.6 OEU08274.1 - 2.6e-13 50.6 0.0 6.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_TAC_4 PF08748.11 OEU08274.1 - 0.00096 19.5 0.8 0.0024 18.2 0.8 1.7 1 0 0 1 1 1 1 Phage tail assembly chaperone 2OG-FeII_Oxy_5 PF13759.6 OEU08274.1 - 0.0039 17.6 0.3 0.05 14.0 0.0 2.7 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase Nkap_C PF06047.11 OEU08274.1 - 0.49 10.5 2.7 0.92 9.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain Pex14_N PF04695.13 OEU08274.1 - 3 8.5 18.4 2.2 8.9 6.4 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cwf_Cwc_15 PF04889.12 OEU08274.1 - 5.6 6.6 25.1 0.036 13.8 5.9 3.5 3 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Phostensin_N PF13916.6 OEU08274.1 - 6 7.3 7.0 1.8 8.9 2.4 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal zf-RING_2 PF13639.6 OEU08275.1 - 4.2e-12 46.2 11.7 4.9e-12 46.0 11.7 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU08275.1 - 2.6e-09 36.7 7.5 2.6e-09 36.7 7.5 1.5 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU08275.1 - 1.1e-07 32.0 14.6 6.1e-07 29.6 14.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU08275.1 - 4.2e-07 29.7 11.7 8.7e-07 28.7 11.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU08275.1 - 7.2e-06 25.8 11.4 1.1e-05 25.2 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU08275.1 - 2.8e-05 24.0 9.5 3.7e-05 23.6 9.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU08275.1 - 6.8e-05 22.8 10.8 9.3e-05 22.4 10.8 1.2 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OEU08275.1 - 0.00063 19.3 7.9 0.00087 18.9 7.9 1.3 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OEU08275.1 - 0.00089 19.4 7.1 0.0015 18.6 7.1 1.5 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OEU08275.1 - 0.0013 18.7 7.7 0.003 17.6 7.7 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OEU08275.1 - 0.0052 16.6 10.7 0.0076 16.1 10.7 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OEU08275.1 - 0.026 14.4 1.3 0.026 14.4 1.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OEU08275.1 - 0.19 11.9 9.9 1.5 9.0 9.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OEU08275.1 - 0.62 9.9 8.0 0.9 9.4 8.0 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 OEU08275.1 - 1.3 8.4 4.2 4.3 6.6 0.1 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger Cupin_2 PF07883.11 OEU08277.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Herpeto_peptide PF14409.6 OEU08278.1 - 0.0059 16.8 0.1 3.9 7.8 0.0 2.4 2 0 0 2 2 2 2 Ribosomally synthesized peptide in Herpetosiphon MspA PF09203.11 OEU08278.1 - 0.025 14.5 4.2 2.8 7.8 0.2 2.7 2 1 1 3 3 3 0 MspA DUF2937 PF11157.8 OEU08283.1 - 0.0099 15.6 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Gly_transf_sug PF04488.15 OEU08284.1 - 1.3e-08 35.3 1.7 2.1e-08 34.7 0.3 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU08284.1 - 0.00043 19.7 0.1 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 OEU08285.1 - 2.7e-07 31.4 0.1 1.5e-06 29.0 0.0 2.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PPV_E2_C PF00511.17 OEU08285.1 - 0.81 9.9 3.7 2.3 8.4 3.7 1.7 1 0 0 1 1 1 0 E2 (early) protein, C terminal Cu-oxidase_2 PF07731.14 OEU08286.1 - 1.6e-23 82.9 2.0 1.6e-23 82.9 2.0 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OEU08286.1 - 2.4e-11 43.7 7.6 3.6e-08 33.5 0.4 4.0 4 0 0 4 4 4 3 Multicopper oxidase Abhydrolase_1 PF00561.20 OEU08287.1 - 8.7e-12 45.2 0.8 5.5e-09 36.0 0.1 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU08287.1 - 0.00024 21.8 0.0 0.00041 21.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU08287.1 - 0.00049 19.4 0.0 0.078 12.2 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 CDC45 PF02724.14 OEU08287.1 - 0.14 10.5 8.6 0.17 10.2 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 OEU08287.1 - 0.48 9.8 8.1 0.71 9.2 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 OEU08287.1 - 0.92 8.7 7.1 1.3 8.1 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 OEU08287.1 - 2.7 8.0 5.8 4.2 7.4 5.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Roughex PF06020.11 OEU08287.1 - 3.4 6.7 14.9 4.7 6.2 14.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TP53IP5 PF15331.6 OEU08287.1 - 3.5 7.7 6.6 5 7.2 6.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 NOA36 PF06524.12 OEU08287.1 - 4.5 6.5 13.5 7.1 5.9 13.5 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 OEU08287.1 - 7.9 4.9 14.6 10 4.5 14.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Polyoma_coat2 PF00761.20 OEU08288.1 - 2.2 7.9 4.7 3.3 7.3 4.7 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein zf-CCCH_4 PF18044.1 OEU08289.1 - 1.3e-08 34.4 7.3 1.3e-08 34.4 7.3 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 OEU08289.1 - 3.4e-08 33.2 4.6 3.4e-08 33.2 4.6 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU08289.1 - 7.9e-06 25.8 8.6 7.9e-06 25.8 8.6 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_2 PF14608.6 OEU08289.1 - 1.9 9.1 12.2 0.073 13.6 5.7 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DNA_methylase PF00145.17 OEU08290.1 - 9.1e-41 140.3 8.3 1.2e-38 133.3 0.0 3.3 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase DUF3439 PF11921.8 OEU08290.1 - 0.32 11.0 12.0 4.4 7.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) Macoilin PF09726.9 OEU08290.1 - 3.4 6.1 12.0 5.4 5.4 12.0 1.3 1 0 0 1 1 1 0 Macoilin family WBP-1 PF11669.8 OEU08292.1 - 5.2 7.8 6.0 4.5 8.0 0.4 3.2 4 0 0 4 4 4 0 WW domain-binding protein 1 PGPGW PF09656.10 OEU08297.1 - 0.0012 18.4 1.5 0.0018 17.7 1.5 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) SUIM_assoc PF16619.5 OEU08297.1 - 0.01 15.9 59.2 0.034 14.2 0.0 7.1 6 2 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 PDZ_6 PF17820.1 OEU08297.1 - 0.016 15.1 0.4 6 6.8 0.1 2.5 2 0 0 2 2 2 0 PDZ domain DUF285 PF03382.14 OEU08299.1 - 5.5e-179 584.6 78.6 3.3e-34 117.2 4.5 3.9 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 BssS PF13991.6 OEU08299.1 - 3.1 7.9 8.4 56 3.9 0.0 5.7 6 1 2 8 8 8 0 BssS protein family Methyltransf_16 PF10294.9 OEU08300.1 - 8.1e-15 55.0 10.2 1.1e-07 31.8 0.9 3.2 1 1 2 3 3 3 3 Lysine methyltransferase Methyltransf_23 PF13489.6 OEU08300.1 - 0.043 13.6 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OEU08300.1 - 0.058 12.9 5.9 0.85 9.1 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 OEU08300.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OEU08300.1 - 0.33 10.9 1.4 0.86 9.6 1.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain ABC2_membrane_3 PF12698.7 OEU08300.1 - 3.2 6.8 13.5 5.7 5.9 13.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Sel1 PF08238.12 OEU08301.1 - 7e-06 26.6 5.6 0.0087 16.7 0.1 3.3 3 0 0 3 3 3 2 Sel1 repeat zf-MYND PF01753.18 OEU08301.1 - 0.0015 18.5 14.1 0.0015 18.5 14.1 2.9 2 1 0 2 2 2 1 MYND finger MRC1 PF09444.10 OEU08301.1 - 0.044 14.3 3.4 0.073 13.6 3.4 1.3 1 0 0 1 1 1 0 MRC1-like domain SSURE PF11966.8 OEU08303.1 - 0.0014 18.3 0.3 1.4 8.7 0.1 2.5 2 0 0 2 2 2 2 Fibronectin-binding repeat Imm10 PF15588.6 OEU08303.1 - 0.017 15.2 0.5 4.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Immunity protein 10 Esterase PF00756.20 OEU08304.1 - 5.2e-10 39.4 0.1 9.3e-10 38.6 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 OEU08305.1 - 4.6e-16 59.0 0.0 6e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OEU08305.1 - 0.031 13.6 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OEU08305.1 - 0.032 14.1 0.0 0.035 13.9 0.0 1.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 OEU08305.1 - 0.038 13.5 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OEU08305.1 - 0.096 12.4 0.2 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cyt_b-c1_8 PF10890.8 OEU08305.1 - 0.16 12.4 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Ion_trans PF00520.31 OEU08306.1 - 2e-48 164.8 57.8 1.5e-13 50.6 8.4 4.6 4 1 0 4 4 4 4 Ion transport protein SH3_17 PF18350.1 OEU08306.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain Pkinase PF00069.25 OEU08307.1 - 2.5e-45 154.9 0.0 5.9e-45 153.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08307.1 - 1.4e-15 57.3 0.0 1.1e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU08307.1 - 0.0078 15.0 0.0 0.015 14.1 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU08307.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU08307.1 - 0.15 11.4 0.0 5.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like PDZ_6 PF17820.1 OEU08308.1 - 9.2e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU08308.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 OEU08308.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain RskA PF10099.9 OEU08309.1 - 0.034 14.5 0.0 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 OEU08309.1 - 0.13 11.9 26.9 0.037 13.6 19.0 2.8 3 0 0 3 3 3 0 Spt20 family Presenilin PF01080.17 OEU08309.1 - 0.13 11.0 9.8 0.54 9.0 9.6 2.0 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 OEU08309.1 - 0.94 9.4 19.9 0.2 11.6 16.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WBP-1 PF11669.8 OEU08309.1 - 5.1 7.8 8.1 23 5.7 0.1 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 Peptidase_S49_N PF08496.10 OEU08309.1 - 8 6.5 9.8 20 5.2 9.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.9 OEU08309.1 - 9.1 5.8 25.7 1.1 8.8 8.1 2.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 OEU08310.1 - 9.4e-05 22.1 13.7 9.4e-05 22.1 13.7 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein PCIF1_WW PF12237.8 OEU08310.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain CDC45 PF02724.14 OEU08310.1 - 0.082 11.2 7.4 0.0076 14.6 3.4 1.4 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 OEU08310.1 - 0.59 8.2 22.7 0.079 11.1 18.7 1.5 2 0 0 2 2 2 0 DNA polymerase phi CENP-Q PF13094.6 OEU08310.1 - 0.76 10.0 5.5 2.1 8.5 5.5 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SGT1 PF07093.11 OEU08310.1 - 5.4 5.3 16.8 2.2 6.6 14.0 1.6 2 0 0 2 2 2 0 SGT1 protein SCHIP-1 PF10148.9 OEU08310.1 - 9.9 5.7 8.8 27 4.3 8.8 1.7 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 TPR_2 PF07719.17 OEU08311.1 - 0.0034 17.4 0.0 4.7 7.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU08311.1 - 0.021 15.3 5.4 9.8 6.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU08311.1 - 0.11 13.4 1.6 26 6.0 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat NUP50 PF08911.11 OEU08312.1 - 1.4e-06 28.9 7.2 1.4e-06 28.9 7.2 4.1 3 2 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 OEU08312.1 - 4.2e-06 27.0 0.2 0.00017 21.8 0.1 2.5 1 1 1 2 2 2 1 RanBP1 domain NusG_add PF18298.1 OEU08312.1 - 0.046 13.9 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 NusG additional domain Patatin PF01734.22 OEU08313.1 - 2.3e-11 44.3 0.0 4.4e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase APOBEC_C PF05240.14 OEU08313.1 - 0.44 10.5 2.3 11 6.1 0.1 2.8 3 0 0 3 3 3 0 APOBEC-like C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 OEU08314.1 - 6.7e-12 46.1 0.0 9.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Me-amine-dh_H PF06433.11 OEU08314.1 - 0.14 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Glyco_hydro_99 PF16317.5 OEU08315.1 - 1.9e-12 47.0 0.5 7.2e-11 41.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 99 Orf78 PF06024.12 OEU08315.1 - 0.00019 21.7 2.1 0.094 13.0 0.0 3.2 3 0 0 3 3 3 2 Orf78 (ac78) RIO1 PF01163.22 OEU08317.1 - 6.2e-37 127.0 0.0 1.2e-36 126.0 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OEU08317.1 - 3.8e-25 87.9 0.0 8.5e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OEU08317.1 - 3.1e-08 33.9 0.7 0.00083 19.3 0.1 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 OEU08317.1 - 3.5e-05 23.3 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OEU08317.1 - 0.0024 17.3 0.0 0.025 14.0 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHASE3 PF05227.13 OEU08318.1 - 0.067 13.1 4.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 CHASE3 domain PNPase_C PF12111.8 OEU08318.1 - 0.11 12.0 0.8 0.24 10.9 0.8 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal zinc_ribbon_2 PF13240.6 OEU08318.1 - 0.13 12.1 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 OEU08318.1 - 0.13 12.3 1.7 0.3 11.2 1.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Sulfotransfer_2 PF03567.14 OEU08319.1 - 4.7e-06 26.7 8.4 2.6e-05 24.2 8.4 2.0 1 1 0 1 1 1 1 Sulfotransferase family DUF4834 PF16118.5 OEU08319.1 - 0.05 14.6 4.5 0.67 11.0 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SURF2 PF05477.11 OEU08319.1 - 3.9 7.1 8.5 0.83 9.3 2.5 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) AMP-binding PF00501.28 OEU08321.1 - 2e-63 214.5 0.0 9.4e-63 212.3 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OEU08321.1 - 2e-53 181.2 0.0 3.9e-53 180.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OEU08321.1 - 5.3e-13 49.0 0.0 6.9e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OEU08321.1 - 9.7e-12 45.1 0.1 2.8e-11 43.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OEU08321.1 - 9.8e-10 39.3 0.5 7.1e-09 36.5 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OEU08321.1 - 0.00022 20.3 0.0 0.45 9.5 0.0 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OEU08321.1 - 0.008 15.6 0.3 0.7 9.2 0.1 2.5 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OEU08321.1 - 0.0093 15.1 0.0 3.1 6.8 0.0 2.5 2 0 0 2 2 2 2 RmlD substrate binding domain Sigma54_activ_2 PF14532.6 OEU08321.1 - 0.16 12.1 0.1 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Polysacc_synt_2 PF02719.15 OEU08321.1 - 0.82 8.7 2.0 9 5.3 0.0 2.9 3 1 1 4 4 4 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 OEU08322.1 - 3.7e-59 200.3 0.0 4.1e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08322.1 - 5.2e-27 94.8 0.0 6.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU08322.1 - 0.00026 21.0 0.0 0.22 11.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU08322.1 - 0.0017 17.7 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OEU08322.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OEU08322.1 - 0.024 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4042 PF13251.6 OEU08323.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) SelK_SelG PF10961.8 OEU08323.1 - 0.014 16.0 3.1 0.035 14.7 0.8 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF4813 PF16072.5 OEU08323.1 - 4.6 6.8 4.9 6.7 6.3 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Ca_chan_IQ PF08763.11 OEU08324.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Pyr_redox_2 PF07992.14 OEU08325.1 - 7.1e-28 97.7 0.0 1.4e-26 93.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU08325.1 - 9.1e-09 35.8 0.1 9.9e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU08325.1 - 0.0074 16.3 0.0 2.5 8.1 0.0 3.5 2 2 2 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OEU08325.1 - 0.1 12.9 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Eno-Rase_NADH_b PF12242.8 OEU08325.1 - 0.16 11.8 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 OEU08325.1 - 1.3 9.5 3.1 5.9 7.4 0.3 3.3 3 1 0 3 3 3 0 Putative NAD(P)-binding TPT PF03151.16 OEU08326.1 - 3.5e-20 72.5 4.1 7.5e-20 71.4 4.1 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OEU08326.1 - 2.6e-06 26.9 5.2 3.8e-06 26.3 5.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU08326.1 - 0.0003 21.0 13.1 0.0025 18.0 4.6 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3188 PF11384.8 OEU08326.1 - 0.09 12.5 0.3 0.09 12.5 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) CcmE PF03100.15 OEU08326.1 - 0.12 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 CcmE DUF4149 PF13664.6 OEU08326.1 - 4 7.8 6.9 6.9 7.1 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Pribosyltran PF00156.27 OEU08327.1 - 2.8e-14 53.0 0.0 3.1e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AAA_19 PF13245.6 OEU08327.1 - 0.2 12.0 0.3 0.47 10.8 0.2 1.6 1 1 0 2 2 2 0 AAA domain Helicase_C PF00271.31 OEU08328.1 - 5.8e-16 58.8 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OEU08328.1 - 3e-13 50.0 0.1 1e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OEU08328.1 - 1.5e-05 24.9 0.3 4.2e-05 23.4 0.3 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OEU08328.1 - 0.027 14.7 0.8 0.26 11.6 0.8 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OEU08328.1 - 0.027 14.5 0.1 5.8 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 OEU08328.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OEU08328.1 - 0.16 12.4 0.0 0.66 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 OEU08329.1 - 3.6e-06 27.8 0.0 6.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU08329.1 - 0.14 12.8 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_hydro_18 PF00704.28 OEU08330.1 - 4.5e-19 69.3 0.1 5.5e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OEU08330.1 - 7.6e-06 26.3 9.1 7.6e-06 26.3 9.1 3.1 3 1 0 3 3 3 1 Chitin recognition protein ShK PF01549.24 OEU08330.1 - 7.3 7.2 16.2 0.89 10.1 5.1 3.4 2 1 0 2 2 2 0 ShK domain-like tRNA-synt_1 PF00133.22 OEU08331.1 - 1.3e-37 129.4 0.0 2.5e-22 78.9 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OEU08331.1 - 2.1e-19 69.6 0.3 3.3e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OEU08331.1 - 1.4e-12 47.9 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OEU08331.1 - 4.7e-07 29.4 0.0 9.5e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Thioredoxin PF00085.20 OEU08332.1 - 0.00054 19.9 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin LicD PF04991.13 OEU08333.1 - 0.0011 19.2 0.7 0.0011 19.2 0.7 2.6 3 0 0 3 3 3 1 LicD family TrbC PF04956.13 OEU08334.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family Protocadherin PF08374.11 OEU08334.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Protocadherin Hep_59 PF07052.11 OEU08336.1 - 0.62 10.8 6.3 1.2 10.0 0.5 2.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 ChlamPMP_M PF07548.11 OEU08336.1 - 3.1 7.7 7.1 0.79 9.6 3.5 1.8 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain OmdA PF13376.6 OEU08338.1 - 0.034 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Peptidase_M16_C PF05193.21 OEU08338.1 - 0.098 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain Ribosomal_L34e PF01199.18 OEU08339.1 - 3.7e-32 110.5 7.3 4.6e-32 110.2 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1977 PF09320.11 OEU08339.1 - 0.11 12.7 2.4 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) Ribosomal_L36e PF01158.18 OEU08340.1 - 3.2e-31 107.4 4.0 3.6e-31 107.3 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DDR PF08841.10 OEU08340.1 - 0.034 13.1 0.1 0.039 12.9 0.1 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain THF_DHG_CYH PF00763.23 OEU08341.1 - 4.2e-22 78.6 0.0 8.4e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OEU08341.1 - 1.7e-15 56.7 0.9 2.7e-13 49.5 0.9 3.4 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPR_12 PF13424.6 OEU08342.1 - 6.7e-19 68.0 22.6 2.1e-11 43.9 0.2 6.8 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08342.1 - 9.6e-18 62.8 13.5 0.048 13.8 0.0 8.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 OEU08342.1 - 3.8e-17 61.3 11.5 0.023 14.5 0.4 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OEU08342.1 - 3.7e-16 57.9 5.2 0.00073 19.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU08342.1 - 2.7e-14 52.1 13.5 0.06 13.6 1.7 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 OEU08342.1 - 8.9e-09 35.5 3.3 0.37 11.7 0.0 6.4 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU08342.1 - 6e-08 33.2 0.0 0.03 15.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU08342.1 - 5.8e-07 29.9 3.2 0.097 13.2 0.3 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 OEU08342.1 - 5.9e-07 29.4 4.7 0.017 14.8 2.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 OEU08342.1 - 8.8e-07 28.5 11.2 0.0092 15.6 0.0 5.1 5 0 0 5 5 5 2 TPR repeat RPN7 PF10602.9 OEU08342.1 - 2.4e-05 24.1 6.8 0.19 11.5 0.0 4.7 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_10 PF13374.6 OEU08342.1 - 0.00091 19.0 6.2 2.8 7.9 0.0 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU08342.1 - 0.001 19.3 4.2 0.013 15.7 0.1 3.8 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 OEU08342.1 - 0.0026 17.5 3.1 0.027 14.2 0.2 3.5 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 OEU08342.1 - 0.0055 17.3 6.6 15 6.4 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat PPR PF01535.20 OEU08342.1 - 0.043 14.1 0.0 1.3 9.5 0.0 3.2 3 0 0 3 3 2 0 PPR repeat Mga PF05043.13 OEU08342.1 - 0.046 14.3 0.9 2.1 9.0 0.2 3.5 3 0 0 3 3 3 0 Mga helix-turn-helix domain DUF489 PF04356.12 OEU08342.1 - 0.52 10.3 5.9 0.13 12.2 0.3 2.6 2 1 0 3 3 2 0 Protein of unknown function (DUF489) Heme_oxygenase PF01126.20 OEU08343.1 - 1.2e-16 61.2 0.1 1.5e-14 54.3 0.1 2.1 1 1 0 1 1 1 1 Heme oxygenase CPSase_L_D2 PF02786.17 OEU08344.1 - 1e-104 348.6 0.1 4.8e-77 258.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OEU08344.1 - 5.6e-49 165.2 0.0 1.1e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OEU08344.1 - 8.7e-41 139.8 0.0 5.1e-40 137.3 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OEU08344.1 - 5e-40 136.6 0.0 1.1e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 OEU08344.1 - 5.5e-13 48.9 0.2 1.6e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OEU08344.1 - 6.9e-13 48.5 0.1 9e-08 31.9 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OEU08344.1 - 4.9e-12 45.7 0.0 2.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 OEU08344.1 - 1.3e-10 41.3 0.1 2.4e-09 37.3 0.0 3.2 3 0 0 3 3 3 1 MGS-like domain Peptidase_C26 PF07722.13 OEU08344.1 - 0.00015 21.6 0.2 0.012 15.4 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 OEU08344.1 - 0.00078 19.5 0.8 1.5 8.9 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 OEU08344.1 - 0.014 15.2 0.2 0.088 12.6 0.1 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 OEU08344.1 - 0.097 12.1 0.0 15 4.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain ATP-synt_Eps PF04627.13 OEU08345.1 - 8.2e-16 57.7 0.3 1e-15 57.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain BetaGal_dom4_5 PF13364.6 OEU08345.1 - 0.12 13.0 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Trypsin_2 PF13365.6 OEU08346.1 - 2.8e-13 51.0 1.4 1.4e-12 48.7 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain COR PF16095.5 OEU08346.1 - 1.3e-07 31.7 0.0 1.5e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Trypsin PF00089.26 OEU08346.1 - 0.021 14.6 0.3 0.41 10.4 0.1 3.1 2 1 0 2 2 2 0 Trypsin Roc PF08477.13 OEU08346.1 - 0.13 12.5 0.0 0.65 10.2 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Glyco_transf_22 PF03901.17 OEU08347.1 - 9.1e-50 170.1 22.7 6e-45 154.2 18.7 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family IQCJ-SCHIP1 PF15157.6 OEU08347.1 - 3.7 7.4 4.5 1.5 8.6 1.4 1.9 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif TPR_12 PF13424.6 OEU08348.1 - 3.4e-11 43.3 0.5 1e-07 32.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU08348.1 - 4.6e-08 32.7 0.2 0.005 16.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU08348.1 - 1.2e-07 31.4 2.5 0.0033 17.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08348.1 - 1.7e-07 30.8 2.2 0.0017 18.3 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU08348.1 - 2.4e-06 27.1 0.7 1.5 8.6 0.0 3.5 3 0 0 3 3 3 3 TPR repeat SHNi-TPR PF10516.9 OEU08348.1 - 3.1e-05 23.3 0.0 0.026 14.0 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_1 PF00515.28 OEU08348.1 - 4.8e-05 23.0 2.7 0.003 17.3 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU08348.1 - 0.0032 17.4 0.6 0.35 11.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU08348.1 - 0.0068 15.9 0.1 0.0088 15.6 0.1 1.1 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 OEU08348.1 - 0.026 15.3 0.0 6.7 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 OEU08348.1 - 0.036 13.8 1.4 0.16 11.7 0.4 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 OEU08348.1 - 0.071 13.8 1.4 0.78 10.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PAF-AH_p_II PF03403.13 OEU08350.1 - 1.3e-15 56.8 0.0 1.4e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OEU08350.1 - 1.7e-10 40.3 0.0 1.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 OEU08350.1 - 6.7e-07 28.6 0.0 9.5e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.8 OEU08350.1 - 7.5e-05 22.1 0.0 0.35 10.1 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU08350.1 - 0.00012 22.7 0.0 0.0042 17.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU08350.1 - 0.00018 21.3 0.0 0.0022 17.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 OEU08350.1 - 0.00024 21.0 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 OEU08350.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OEU08350.1 - 0.011 15.5 0.0 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OEU08350.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 OEU08350.1 - 0.035 13.7 0.0 7.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_8 PF06259.12 OEU08350.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 OEU08350.1 - 0.081 12.8 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 OEU08350.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Ribophorin_I PF04597.14 OEU08352.1 - 0.13 11.4 3.4 1.4 8.0 0.3 2.5 1 1 1 3 3 3 0 Ribophorin I HECT PF00632.25 OEU08353.1 - 2.7e-87 293.1 0.0 3.3e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Methyltransf_11 PF08241.12 OEU08354.1 - 2.7e-12 47.1 0.0 4.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU08354.1 - 9.3e-08 32.7 0.0 1.6e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU08354.1 - 5.6e-07 29.5 0.0 9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU08354.1 - 1.2e-06 29.1 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU08354.1 - 1.6e-06 28.0 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU08354.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 OEU08354.1 - 0.00076 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 OEU08354.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_29 PF03141.16 OEU08354.1 - 0.0089 14.6 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase N6_N4_Mtase PF01555.18 OEU08354.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA methylase MetW PF07021.12 OEU08354.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW SL4P PF17618.2 OEU08355.1 - 0.057 13.5 0.6 0.88 9.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein Pep1_7 PF17232.2 OEU08356.1 - 9.3 6.8 7.8 1.1 9.8 1.7 2.7 2 1 0 2 2 2 0 Elicitor peptide 1-7 Pox_A12 PF04651.13 OEU08357.1 - 0.21 11.6 4.3 0.14 12.2 1.9 1.7 1 1 1 2 2 2 0 Poxvirus A12 protein CDC45 PF02724.14 OEU08357.1 - 7.8 4.6 16.1 10 4.3 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein GHMP_kinases_N PF00288.26 OEU08358.1 - 0.97 9.7 4.1 7.4 6.9 1.3 2.5 2 0 0 2 2 2 0 GHMP kinases N terminal domain BTP PF05232.12 OEU08359.1 - 0.24 11.5 1.3 2.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Chlorhexidine efflux transporter LCIB_C_CA PF18599.1 OEU08360.1 - 5.1e-54 182.9 0.0 6e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases NAD_binding_1 PF00175.21 OEU08362.1 - 2.9e-12 47.2 0.0 1.2e-11 45.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OEU08362.1 - 0.0014 18.8 0.0 0.08 13.1 0.0 2.1 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Pyrid_oxidase_2 PF13883.6 OEU08363.1 - 2.1e-35 122.2 0.0 2.7e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Yae1_N PF09811.9 OEU08365.1 - 0.00068 19.3 19.9 86 3.0 3.5 6.3 1 1 1 2 2 2 0 Essential protein Yae1, N terminal MspA PF09203.11 OEU08365.1 - 0.14 12.0 1.9 2.1 8.1 1.9 2.1 1 1 0 1 1 1 0 MspA Gly-zipper_OmpA PF13436.6 OEU08365.1 - 0.17 11.7 19.9 1.8e+04 -5.7 19.9 3.9 1 1 0 1 1 0 0 Glycine-zipper domain OMP_b-brl PF13505.6 OEU08365.1 - 0.17 12.0 0.1 7.1 6.7 0.1 2.8 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain Bacteriocin_IIc PF10439.9 OEU08365.1 - 0.21 11.7 18.5 4.9 7.3 1.8 3.9 1 1 2 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.9 OEU08365.1 - 0.25 11.7 14.2 1.8e+04 -4.3 14.2 4.8 1 1 0 1 1 0 0 Reactive mitochondrial oxygen species modulator 1 OpcA PF07239.11 OEU08365.1 - 0.73 9.5 5.5 11 5.6 0.2 3.4 1 1 3 4 4 4 0 Outer membrane protein OpcA Keratin_2_head PF16208.5 OEU08365.1 - 1 9.5 11.3 2.7e+02 1.6 11.3 2.5 1 1 0 1 1 1 0 Keratin type II head Transgly_assoc PF04226.13 OEU08365.1 - 2 8.7 15.6 49 4.3 0.6 4.5 1 1 1 2 2 2 0 Transglycosylase associated protein Gly-zipper_Omp PF13488.6 OEU08365.1 - 4.4 7.4 18.7 1e+04 -3.4 18.7 3.2 1 1 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 OEU08365.1 - 5.9 6.8 22.2 1.8e+04 -7.9 22.2 3.6 1 1 0 1 1 0 0 Glycine zipper 2TM domain DUF285 PF03382.14 OEU08366.1 - 1.1e-131 431.9 53.6 7.3e-37 125.8 7.7 4.0 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 SR1P PF13790.6 OEU08366.1 - 0.0029 17.7 2.9 1.1e+02 3.0 0.0 6.3 7 0 0 7 7 7 0 SR1 protein PCP PF02429.15 OEU08366.1 - 0.0048 17.2 0.8 6.7 7.0 0.1 3.9 1 1 3 4 4 4 1 Peridinin-chlorophyll A binding protein Lenti_VIF_2 PF07401.12 OEU08366.1 - 0.012 14.9 2.7 0.29 10.5 0.1 3.2 3 0 0 3 3 3 0 Bovine Lentivirus VIF protein PhyH PF05721.13 OEU08367.1 - 6e-10 39.7 0.0 1.4e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) eIF3_subunit PF08597.10 OEU08367.1 - 0.021 14.8 4.9 0.044 13.7 4.9 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit UBN_AB PF14075.6 OEU08367.1 - 0.023 14.4 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF3791 PF12668.7 OEU08367.1 - 0.057 13.5 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) MBD_C PF14048.6 OEU08367.1 - 0.17 12.6 1.7 4.2 8.1 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF3439 PF11921.8 OEU08368.1 - 3.7 7.5 10.0 0.045 13.7 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pro_isomerase PF00160.21 OEU08369.1 - 3.5e-06 27.4 0.0 4.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cNMP_binding PF00027.29 OEU08370.1 - 1.1e-36 124.8 0.3 7.3e-18 64.4 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain NUFIP2 PF15293.6 OEU08370.1 - 0.096 11.6 1.5 0.16 10.8 1.5 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.25 OEU08371.1 - 5.8e-61 206.2 0.0 6.8e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08371.1 - 2.5e-32 112.2 0.0 3.2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OEU08371.1 - 0.0052 17.5 1.5 0.0093 16.6 1.5 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OEU08371.1 - 0.056 12.8 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OEU08371.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GreA_GreB PF01272.19 OEU08372.1 - 0.11 12.5 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term Myosin_N PF02736.19 OEU08372.1 - 0.11 12.3 0.0 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain ARPC4 PF05856.12 OEU08374.1 - 6.4e-32 110.5 0.6 7.3e-32 110.3 0.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Peptidase_S78 PF04586.17 OEU08374.1 - 0.05 13.8 0.0 0.069 13.3 0.0 1.4 1 1 0 1 1 1 0 Caudovirus prohead serine protease Lactamase_B_6 PF16661.5 OEU08375.1 - 3.6e-26 91.8 0.0 5.1e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 OEU08375.1 - 5e-12 46.1 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain TPR_14 PF13428.6 OEU08376.1 - 2.1e-31 105.9 17.4 0.00047 20.8 0.3 12.5 6 4 8 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08376.1 - 1.6e-27 93.4 14.6 0.0045 17.0 0.1 13.3 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 OEU08376.1 - 2.5e-27 95.2 3.5 3.6e-05 24.2 0.1 8.7 7 2 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 OEU08376.1 - 2.4e-20 72.6 20.7 0.0065 16.7 0.3 9.9 6 4 2 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 OEU08376.1 - 5.2e-19 68.6 10.8 0.0061 17.2 0.1 8.6 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 OEU08376.1 - 5.3e-17 60.9 5.4 0.00041 20.5 0.1 9.7 11 1 0 11 11 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU08376.1 - 3.4e-14 51.8 7.2 0.076 13.3 0.0 10.4 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU08376.1 - 6.4e-13 47.9 3.5 0.0062 16.3 0.1 9.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU08376.1 - 1.4e-10 40.4 8.7 0.54 10.4 0.3 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU08376.1 - 2.8e-08 33.9 12.9 5.2 7.9 0.1 9.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 OEU08376.1 - 1.1e-07 31.9 7.7 0.76 10.0 0.0 7.4 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU08376.1 - 8.6e-07 28.6 7.0 0.0022 17.4 0.1 5.2 3 1 0 5 5 5 1 MalT-like TPR region TPR_11 PF13414.6 OEU08376.1 - 5e-06 26.1 5.6 2.1 8.1 0.0 7.3 9 0 0 9 9 9 1 TPR repeat TPR_10 PF13374.6 OEU08376.1 - 5e-06 26.2 19.2 2.2 8.2 1.1 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OEU08376.1 - 2.5e-05 23.8 0.0 0.0039 16.6 0.0 4.0 5 0 0 5 5 5 1 Coatomer epsilon subunit Mad3_BUB1_I PF08311.12 OEU08376.1 - 0.00053 20.0 3.6 22 5.0 0.0 6.5 7 1 0 7 7 7 0 Mad3/BUB1 homology region 1 PPR PF01535.20 OEU08376.1 - 0.0024 18.0 7.7 57 4.3 0.0 8.0 10 0 0 10 10 9 0 PPR repeat Fis1_TPR_C PF14853.6 OEU08376.1 - 0.0036 17.3 0.6 0.36 10.9 0.1 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 OEU08376.1 - 0.024 14.6 0.2 3 7.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 OEU08376.1 - 0.069 12.9 0.1 1.2 8.8 0.1 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 OEU08376.1 - 0.074 13.3 5.2 13 6.1 0.4 5.2 5 2 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OEU08376.1 - 1.9 8.9 9.7 17 5.8 0.2 5.2 7 1 0 7 7 6 0 Bacterial transcriptional activator domain Sprouty PF05210.13 OEU08377.1 - 0.24 11.8 1.7 1.7 9.1 1.5 2.1 1 1 1 2 2 2 0 Sprouty protein (Spry) DHHC PF01529.20 OEU08377.1 - 0.34 11.0 2.4 0.45 10.6 2.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase CytB6-F_Fe-S PF08802.10 OEU08379.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit BORCS6 PF10157.9 OEU08379.1 - 0.083 13.1 3.0 0.17 12.1 3.0 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF809 PF05663.11 OEU08379.1 - 0.13 12.4 0.3 0.32 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) TAT_signal PF10518.9 OEU08379.1 - 2.7 8.0 4.7 0.87 9.5 0.2 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence CCDC106 PF15794.5 OEU08379.1 - 3.5 7.3 7.6 6.1 6.5 7.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 APC_N_CC PF16689.5 OEU08381.1 - 0.0094 16.0 7.7 0.071 13.2 0.7 3.3 2 1 1 3 3 3 2 Coiled-coil N-terminus of APC, dimerisation domain DUF724 PF05266.14 OEU08381.1 - 1.9 8.3 14.5 2.2 8.1 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FokI_N PF02981.15 OEU08381.1 - 2.3 8.4 4.7 2.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain HALZ PF02183.18 OEU08381.1 - 3 8.1 15.2 3.7 7.8 0.4 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper PKcGMP_CC PF16808.5 OEU08382.1 - 0.011 15.6 0.9 0.025 14.4 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1524 PF07510.11 OEU08383.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) DUF285 PF03382.14 OEU08384.1 - 6.2e-16 58.3 0.1 9.8e-16 57.6 0.1 1.2 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 DGF-1_C PF11040.8 OEU08385.1 - 0.17 11.9 4.3 0.1 12.6 0.4 2.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Apis_Csd PF11671.8 OEU08386.1 - 0.057 13.4 0.9 0.057 13.4 0.9 3.3 3 0 0 3 3 3 0 Complementary sex determiner protein FAM176 PF14851.6 OEU08386.1 - 0.079 12.6 0.1 0.079 12.6 0.1 2.8 2 1 1 3 3 3 0 FAM176 family CytochromB561_N PF09786.9 OEU08386.1 - 0.44 9.5 7.5 0.15 11.0 4.5 1.6 2 0 0 2 2 2 0 Cytochrome B561, N terminal Dsh_C PF12316.8 OEU08386.1 - 1.5 9.2 19.6 0.035 14.5 5.8 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Acetyltransf_10 PF13673.7 OEU08387.1 - 9.1e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU08387.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU08387.1 - 8.4e-05 22.9 0.0 0.00019 21.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribosomal_S5 PF00333.20 OEU08388.1 - 2.2e-19 69.2 0.1 4.6e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OEU08388.1 - 2.1e-17 62.3 0.1 2.9e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Agenet PF05641.12 OEU08389.1 - 0.00059 20.3 2.5 0.00067 20.1 0.7 2.1 2 0 0 2 2 2 1 Agenet domain HTH_DeoR PF08220.12 OEU08389.1 - 0.0025 17.5 0.1 0.0087 15.8 0.0 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 OEU08389.1 - 0.0045 16.5 0.0 0.022 14.3 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding Dimerisation2 PF16864.5 OEU08389.1 - 0.021 14.8 0.0 0.06 13.3 0.0 1.7 2 0 0 2 2 2 0 Dimerisation domain HTH_AsnC-type PF13404.6 OEU08389.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TrmB PF01978.19 OEU08389.1 - 0.082 12.8 0.0 2 8.3 0.0 2.5 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 OEU08389.1 - 0.16 11.8 0.8 8.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Hid1 PF12722.7 OEU08389.1 - 5.2 5.1 15.5 8.8 4.3 15.5 1.3 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein Sulfatase PF00884.23 OEU08390.1 - 1.4e-48 165.9 0.0 2.5e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OEU08390.1 - 2.4e-12 47.6 0.0 5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OEU08390.1 - 0.0062 16.2 0.1 0.032 13.8 0.1 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_38N PF01074.22 OEU08391.1 - 3.7e-91 305.5 2.1 7.7e-91 304.4 2.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain MGAT2 PF05060.14 OEU08391.1 - 1.2e-49 169.3 0.9 5.8e-49 167.0 0.9 2.0 1 1 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Alpha-mann_mid PF09261.11 OEU08391.1 - 9.9e-22 76.9 0.5 2.7e-21 75.5 0.5 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 OEU08391.1 - 1.3e-10 41.7 0.1 3.4e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain DUF2457 PF10446.9 OEU08391.1 - 0.0041 16.3 9.0 0.0078 15.4 9.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Pentapeptide PF00805.22 OEU08392.1 - 1.2e-21 76.0 11.2 2.5e-10 39.8 0.2 3.3 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OEU08392.1 - 6.8e-14 51.8 7.3 1.2e-07 31.8 0.6 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 OEU08392.1 - 3.3e-10 39.9 3.6 4.2e-09 36.4 0.8 2.9 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Isochorismatase PF00857.20 OEU08393.1 - 6.4e-11 42.7 0.0 1.2e-08 35.3 0.0 2.4 2 1 0 2 2 2 2 Isochorismatase family Yae1_N PF09811.9 OEU08394.1 - 1.8e-05 24.3 24.8 1.9 8.2 0.1 7.6 5 3 2 7 7 7 5 Essential protein Yae1, N terminal MspA PF09203.11 OEU08394.1 - 2 8.2 3.7 41 4.0 3.7 2.4 1 1 0 1 1 1 0 MspA Fasciclin PF02469.22 OEU08395.1 - 1.1e-14 54.7 0.0 3e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 Fasciclin domain M64_N PF16217.5 OEU08395.1 - 0.11 12.1 0.2 0.26 10.9 0.1 1.7 2 0 0 2 2 2 0 Peptidase M64 N-terminus His_Phos_1 PF00300.22 OEU08396.1 - 2.1e-23 83.0 0.9 4.1e-15 56.0 0.4 2.6 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) EF-hand_6 PF13405.6 OEU08396.1 - 0.031 14.2 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain GDP_Man_Dehyd PF16363.5 OEU08397.1 - 1.1e-56 192.7 0.1 2.9e-56 191.3 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU08397.1 - 5.3e-49 166.8 0.0 8e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU08397.1 - 2.8e-11 42.9 0.0 4.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU08397.1 - 5.3e-11 42.2 0.1 2.6e-06 26.8 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OEU08397.1 - 3.6e-10 39.5 0.1 5.4e-05 22.5 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OEU08397.1 - 3.3e-08 33.0 0.0 5.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OEU08397.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 OEU08397.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.16 OEU08398.1 - 2.5e-33 115.5 29.1 2.5e-33 115.5 29.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU08398.1 - 1.4e-11 43.9 16.4 1.2e-08 34.3 3.4 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter PUCC PF03209.15 OEU08398.1 - 0.00047 19.3 6.9 0.00073 18.6 6.9 1.2 1 0 0 1 1 1 1 PUCC protein TRI12 PF06609.13 OEU08398.1 - 0.0016 17.0 1.7 0.043 12.2 0.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phostensin_N PF13916.6 OEU08398.1 - 0.33 11.3 3.3 13 6.2 0.7 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SBF PF01758.16 OEU08399.1 - 2.2e-20 73.2 7.7 2.2e-20 73.2 7.7 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 OEU08399.1 - 7.2e-05 22.2 13.2 0.00011 21.7 13.2 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Bestrophin PF01062.21 OEU08399.1 - 0.083 12.3 3.9 4.5 6.6 2.3 2.3 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Aldo_ket_red PF00248.21 OEU08400.1 - 4.7e-13 49.0 0.9 6.9e-13 48.4 0.9 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CPL PF08144.11 OEU08400.1 - 0.051 13.9 1.2 0.26 11.6 0.8 2.1 2 0 0 2 2 2 0 CPL (NUC119) domain LRR_6 PF13516.6 OEU08402.1 - 0.13 12.3 24.2 8.1 6.8 0.9 6.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OEU08402.1 - 0.81 10.5 16.0 2.5 9.0 0.3 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat Cyclin_N PF00134.23 OEU08403.1 - 2.1e-07 30.7 0.0 3.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Carbam_trans_C PF16861.5 OEU08403.1 - 0.037 13.6 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus DUF2597 PF10772.9 OEU08403.1 - 0.14 12.3 0.2 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) Rotamase_3 PF13616.6 OEU08404.1 - 2e-16 60.6 0.0 3.8e-16 59.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OEU08404.1 - 3.1e-15 56.9 0.0 5.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU08404.1 - 0.11 13.4 0.1 0.15 12.9 0.1 1.7 1 1 0 1 1 1 0 PPIC-type PPIASE domain Secretin_N PF03958.17 OEU08404.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain His_Phos_1 PF00300.22 OEU08405.1 - 7.2e-17 61.7 0.0 3.3e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OEU08405.1 - 9.2e-05 22.0 0.3 0.00097 18.6 0.0 2.1 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) DNA_meth_N PF18284.1 OEU08405.1 - 0.098 12.6 0.9 5.3 7.0 0.1 2.7 2 0 0 2 2 2 0 DNA methylase N-terminal domain Peptidase_M24 PF00557.24 OEU08407.1 - 2.9e-47 161.1 0.0 3.1e-46 157.7 0.0 1.9 1 1 0 1 1 1 1 Metallopeptidase family M24 GTP_EFTU PF00009.27 OEU08408.1 - 2e-30 105.8 1.3 2.8e-29 102.1 1.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OEU08408.1 - 1.1e-21 76.9 0.6 3.8e-21 75.2 0.3 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OEU08408.1 - 3.4e-10 40.0 0.3 9.1e-10 38.6 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OEU08408.1 - 6.1e-07 29.7 0.2 1e-06 28.9 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OEU08408.1 - 2.5e-06 27.2 0.2 4.2e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OEU08408.1 - 5e-06 26.1 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OEU08408.1 - 6.2e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OEU08408.1 - 0.0005 19.6 0.3 0.0018 17.8 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OEU08408.1 - 0.024 14.4 0.3 0.21 11.3 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OEU08408.1 - 0.11 12.2 0.0 0.51 10.1 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 OEU08408.1 - 0.14 11.9 0.0 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3653 PF12375.8 OEU08408.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Phage protein AAA PF00004.29 OEU08411.1 - 2.7e-15 57.0 0.0 2e-14 54.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OEU08411.1 - 1.1e-13 51.3 0.0 3.6e-12 46.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OEU08411.1 - 1.6e-13 50.8 0.1 5.3e-13 49.2 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 OEU08411.1 - 8e-07 29.2 0.0 2e-06 27.8 0.0 1.8 2 1 0 2 2 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OEU08411.1 - 1e-06 29.2 3.5 1.9e-05 25.1 0.2 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OEU08411.1 - 4.5e-06 26.7 0.0 3.1e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU08411.1 - 4.7e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OEU08411.1 - 1.1e-05 25.5 0.0 0.0078 16.2 0.0 2.6 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU08411.1 - 1.3e-05 25.5 1.0 0.00086 19.6 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OEU08411.1 - 7.9e-05 22.5 0.1 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OEU08411.1 - 0.00016 21.5 0.0 0.00053 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OEU08411.1 - 0.00033 20.1 0.0 0.0069 15.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 OEU08411.1 - 0.00057 20.2 0.1 0.0015 18.9 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 OEU08411.1 - 0.001 19.5 0.0 0.0085 16.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OEU08411.1 - 0.0018 17.6 0.0 0.0093 15.2 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OEU08411.1 - 0.0018 18.1 0.1 0.0096 15.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 OEU08411.1 - 0.0019 18.3 0.1 0.77 9.9 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 OEU08411.1 - 0.0029 18.2 0.0 0.011 16.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OEU08411.1 - 0.003 17.6 0.0 0.014 15.5 0.0 2.0 1 1 1 2 2 1 1 AAA domain AAA_25 PF13481.6 OEU08411.1 - 0.005 16.4 0.3 0.023 14.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 OEU08411.1 - 0.0054 16.2 0.0 0.25 10.7 0.0 2.8 3 0 0 3 3 3 1 Bacterial TniB protein DEAD PF00270.29 OEU08411.1 - 0.0054 16.5 0.3 0.85 9.4 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 OEU08411.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OEU08411.1 - 0.011 16.1 0.0 0.033 14.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase TIP49 PF06068.13 OEU08411.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 OEU08411.1 - 0.016 15.0 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 OEU08411.1 - 0.019 14.9 0.1 0.25 11.3 0.0 2.6 2 1 0 2 2 2 0 NACHT domain PhoH PF02562.16 OEU08411.1 - 0.02 14.3 0.1 0.75 9.2 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein MeaB PF03308.16 OEU08411.1 - 0.026 13.5 0.1 0.22 10.4 0.1 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 OEU08411.1 - 0.031 13.4 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 OEU08411.1 - 0.07 13.3 0.7 0.44 10.7 0.4 2.6 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 OEU08411.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Asp_protease_2 PF13650.6 OEU08412.1 - 0.06 14.0 0.0 0.73 10.5 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease tRNA-synt_2 PF00152.20 OEU08414.1 - 1.2e-81 274.3 0.0 2.6e-81 273.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OEU08414.1 - 1e-06 28.6 0.0 6.7e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OEU08414.1 - 0.021 14.3 0.1 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.7 OEU08414.1 - 0.032 13.9 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like GST_C PF00043.25 OEU08415.1 - 0.002 18.3 0.0 0.0035 17.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU08415.1 - 0.0043 17.2 0.0 0.0091 16.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU08415.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Apolipoprotein PF01442.18 OEU08416.1 - 0.00011 22.1 12.3 0.00011 22.1 12.3 3.4 2 2 1 3 3 3 1 Apolipoprotein A1/A4/E domain QIL1 PF15884.5 OEU08416.1 - 0.0032 18.0 14.3 0.27 11.8 4.6 4.1 2 2 1 3 3 3 2 MICOS complex subunit MIC13, QIL1 DUF948 PF06103.11 OEU08416.1 - 0.0035 17.6 11.6 0.0035 17.6 11.6 6.1 3 2 2 6 6 6 2 Bacterial protein of unknown function (DUF948) Phage_B PF02304.15 OEU08416.1 - 0.03 14.7 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 Scaffold protein B CwsA PF10814.8 OEU08416.1 - 0.2 11.8 17.2 0.96 9.6 0.3 5.5 2 1 4 6 6 6 0 Cell wall synthesis protein CwsA DUF3168 PF11367.8 OEU08416.1 - 0.27 11.4 0.9 25 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) DUF3921 PF13060.6 OEU08416.1 - 0.3 11.1 9.2 2.6 8.2 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3921) Baculo_PEP_C PF04513.12 OEU08416.1 - 0.38 10.8 27.1 1.4 9.0 1.4 4.0 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 OEU08416.1 - 0.95 9.2 36.9 1.3 8.7 11.4 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF745) Prominin PF05478.11 OEU08416.1 - 1.2 7.1 27.2 0.0071 14.4 12.7 2.5 2 1 0 2 2 2 0 Prominin Syntaxin_2 PF14523.6 OEU08416.1 - 2.5 8.5 49.7 0.11 12.9 5.3 6.5 2 2 5 7 7 6 0 Syntaxin-like protein DUF3584 PF12128.8 OEU08416.1 - 2.6 5.4 35.8 0.084 10.4 8.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ApoLp-III PF07464.11 OEU08416.1 - 3.5 7.7 48.5 0.17 12.0 29.2 4.7 3 2 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) GGGtGRT PF14057.6 OEU08416.1 - 3.5 6.5 6.4 1.7 7.5 1.6 2.4 1 1 2 3 3 3 0 GGGtGRT protein AAA_13 PF13166.6 OEU08416.1 - 3.7 6.1 44.7 1.2 7.7 20.3 2.3 2 0 0 2 2 2 0 AAA domain DUF4490 PF14892.6 OEU08416.1 - 5.1 7.2 14.1 1.4 9.0 1.5 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4490) MCPsignal PF00015.21 OEU08416.1 - 5.4 6.8 36.1 18 5.1 19.0 4.7 4 1 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1870 PF08965.10 OEU08416.1 - 5.8 7.0 10.6 17 5.5 4.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) DUF1382 PF07131.11 OEU08416.1 - 7.3 6.7 5.9 28 4.8 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) DUF883 PF05957.13 OEU08416.1 - 8.2 7.1 19.4 6.7 7.4 1.4 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 OEU08416.1 - 8.4 6.6 49.4 0.07 13.3 19.5 4.5 2 2 3 5 5 5 0 Fibrinogen alpha/beta chain family DUF892 PF05974.12 OEU08416.1 - 8.9 6.3 22.0 0.05 13.6 4.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF892) UCR_UQCRX_QCR9 PF05365.12 OEU08417.1 - 5e-09 36.0 0.7 8.4e-09 35.2 0.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like HCMV_UL124 PF17609.2 OEU08417.1 - 0.083 13.1 0.4 0.11 12.7 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function Dioxygenase_C PF00775.21 OEU08418.1 - 0.031 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase DUF1415 PF07209.12 OEU08419.1 - 7.3e-10 38.9 2.2 0.00025 20.9 0.2 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1415) CdiA_C_tRNase PF18664.1 OEU08419.1 - 0.14 12.3 0.9 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain Nfu_N PF08712.11 OEU08420.1 - 3.8e-08 33.3 0.0 9.4e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal HEAT_2 PF13646.6 OEU08420.1 - 2e-06 28.1 0.0 0.00047 20.5 0.0 2.7 2 0 0 2 2 2 2 HEAT repeats Virulence_fact PF13769.6 OEU08420.1 - 6.1e-05 23.2 0.1 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 Virulence factor Cortex-I_coil PF09304.10 OEU08421.1 - 2.6 8.3 11.8 2 8.6 0.4 3.3 3 0 0 3 3 3 0 Cortexillin I, coiled coil Memo PF01875.17 OEU08422.1 - 8.9e-62 208.7 0.0 1e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LmjF365940-deam PF14421.6 OEU08423.1 - 0.074 12.7 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases SBF PF01758.16 OEU08424.1 - 6.2e-31 107.6 17.3 1.1e-30 106.8 17.3 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 OEU08424.1 - 2e-12 47.1 20.1 2.4e-12 46.8 20.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) ApoO PF09769.9 OEU08424.1 - 3.2 7.7 5.1 2.5 8.1 0.2 2.8 3 0 0 3 3 3 0 Apolipoprotein O DUF1516 PF07457.11 OEU08425.1 - 0.12 12.6 0.7 0.33 11.2 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) RSN1_7TM PF02714.15 OEU08426.1 - 2.6e-51 174.5 21.2 4.6e-51 173.7 21.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OEU08426.1 - 7.7e-21 75.1 1.2 3.6e-12 46.9 0.1 2.3 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OEU08426.1 - 3.7e-16 59.3 0.6 3.7e-16 59.3 0.6 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport RNA_pol_Rpb2_6 PF00562.28 OEU08427.1 - 4.3e-123 411.2 0.1 6e-123 410.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OEU08427.1 - 1.3e-61 207.6 0.0 1.9e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OEU08427.1 - 2.1e-47 161.2 0.0 4e-47 160.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OEU08427.1 - 3.4e-27 94.7 0.3 9.2e-27 93.3 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 OEU08427.1 - 1.4e-25 89.3 0.6 3e-25 88.3 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OEU08427.1 - 3.1e-25 88.1 0.1 7.8e-25 86.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OEU08427.1 - 2.7e-18 66.3 3.2 6.9e-18 65.0 3.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Mt_ATP_synt PF15704.5 OEU08427.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit GATase_3 PF07685.14 OEU08429.1 - 2.4e-24 86.0 0.0 3.5e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 OEU08429.1 - 1.6e-06 28.2 0.0 5.2e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 OEU08429.1 - 1.8e-05 24.7 0.2 0.00059 19.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain BPL_N PF09825.9 OEU08429.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2981 PF11200.8 OEU08430.1 - 2.1 8.0 9.3 12 5.6 9.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) Lipase_3 PF01764.25 OEU08431.1 - 0.00032 20.6 0.1 0.0008 19.3 0.1 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OEU08431.1 - 0.0098 15.5 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF2207 PF09972.9 OEU08431.1 - 3.2 6.4 9.3 9.2 4.9 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Helicase_C PF00271.31 OEU08432.1 - 3.5e-15 56.3 0.0 1.7e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU08432.1 - 0.0019 17.5 0.0 0.0039 16.4 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 OEU08433.1 - 2.2e-21 76.0 0.0 2.5e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OEU08433.1 - 0.17 11.9 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FAD_binding_2 PF00890.24 OEU08435.1 - 7.9e-83 278.9 0.3 1.4e-82 278.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain ERO1 PF04137.15 OEU08435.1 - 2e-76 257.5 0.7 2.9e-76 257.0 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Cyt-b5 PF00173.28 OEU08435.1 - 1.8e-17 63.2 0.1 4.6e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 OEU08435.1 - 6.5e-10 39.1 0.1 1.5e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU08435.1 - 9.3e-07 28.4 0.6 4e-06 26.3 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU08435.1 - 7.4e-06 25.6 2.0 2.9e-05 23.6 2.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU08435.1 - 0.00015 21.9 0.2 0.00054 20.1 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OEU08435.1 - 0.00097 18.3 0.2 0.16 11.0 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 OEU08435.1 - 0.0047 15.7 3.0 0.031 13.0 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein GMC_oxred_N PF00732.19 OEU08435.1 - 0.0087 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Amino_oxidase PF01593.24 OEU08435.1 - 0.011 15.0 2.2 0.37 10.0 0.1 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase MCRA PF06100.11 OEU08435.1 - 0.013 14.3 0.0 0.075 11.8 0.0 1.9 2 0 0 2 2 2 0 MCRA family Thi4 PF01946.17 OEU08435.1 - 0.017 14.4 2.9 0.92 8.7 0.2 3.2 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.6 OEU08435.1 - 0.041 13.2 0.9 1.9 7.7 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0176_N PF17773.1 OEU08438.1 - 3.7e-17 62.5 0.0 6.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OEU08438.1 - 0.00072 20.0 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 OEU08438.1 - 0.0012 19.2 3.0 0.0012 19.2 3.0 2.1 2 0 0 2 2 2 1 Rhodanase C-terminal DnaJ PF00226.31 OEU08439.1 - 6.5e-24 83.8 1.3 7.1e-24 83.7 1.3 1.0 1 0 0 1 1 1 1 DnaJ domain GATase PF00117.28 OEU08439.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Acylphosphatase PF00708.18 OEU08440.1 - 4.3e-09 36.7 0.0 6.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acylphosphatase GatB_N PF02934.15 OEU08441.1 - 7.4e-94 314.2 0.0 9.8e-94 313.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OEU08441.1 - 3.7e-21 75.5 0.0 8.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 GatB domain Lipocalin_5 PF13924.6 OEU08441.1 - 0.17 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain NUDIX PF00293.28 OEU08442.1 - 3.3e-06 27.2 0.1 5.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1749 PF08538.10 OEU08442.1 - 0.018 14.1 0.2 0.045 12.8 0.1 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1749) DnaJ PF00226.31 OEU08444.1 - 1e-27 96.0 6.9 2.3e-26 91.7 2.1 3.2 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 OEU08444.1 - 6.2e-26 89.1 18.5 7.9e-08 31.8 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08444.1 - 6.5e-22 75.8 30.3 1.5e-05 24.7 0.1 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 OEU08444.1 - 1e-18 67.6 3.1 1e-06 29.3 1.8 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU08444.1 - 1.8e-16 59.5 0.5 5.4e-05 22.8 0.0 5.3 5 0 0 5 5 5 4 TPR repeat TPR_8 PF13181.6 OEU08444.1 - 7.4e-16 57.0 16.8 0.00077 19.5 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OEU08444.1 - 6.8e-15 55.3 12.9 9e-05 22.9 0.1 6.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OEU08444.1 - 4.5e-14 51.9 11.7 0.0015 19.2 1.2 6.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU08444.1 - 1.6e-12 46.5 8.3 0.0011 18.8 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU08444.1 - 8.5e-11 42.0 13.7 0.0022 18.2 0.8 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU08444.1 - 5.7e-06 26.5 15.8 0.0095 16.1 1.4 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OEU08444.1 - 1.1e-05 25.7 13.0 0.047 14.3 0.1 7.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU08444.1 - 3.2e-05 24.0 0.9 2.6 8.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU08444.1 - 5.7e-05 23.2 0.1 0.044 14.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU08444.1 - 0.00045 19.6 0.7 0.12 11.9 0.0 3.6 4 0 0 4 4 4 1 SHNi-TPR TPR_10 PF13374.6 OEU08444.1 - 0.0024 17.7 7.4 3.9 7.5 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 OEU08444.1 - 0.0029 17.6 15.5 0.27 11.3 0.3 5.5 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain SPO22 PF08631.10 OEU08444.1 - 0.042 13.3 4.6 1.8 8.0 0.3 3.4 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like PPR PF01535.20 OEU08444.1 - 0.13 12.6 1.0 40 4.8 0.0 3.9 4 0 0 4 4 2 0 PPR repeat Fis1_TPR_C PF14853.6 OEU08444.1 - 0.13 12.4 3.6 9.8 6.3 0.0 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat NSF PF02071.20 OEU08444.1 - 1.2 10.2 8.9 45 5.5 0.1 4.9 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat Alkyl_sulf_dimr PF14863.6 OEU08444.1 - 6.6 7.2 11.3 16 5.9 0.6 4.0 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation AA_permease_2 PF13520.6 OEU08445.1 - 9.9e-41 139.9 39.0 1.7e-40 139.2 39.0 1.4 1 1 0 1 1 1 1 Amino acid permease DUF1647 PF07801.11 OEU08445.1 - 0.041 13.6 0.7 0.086 12.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) HSF_DNA-bind PF00447.17 OEU08447.1 - 2.1e-14 53.9 1.9 5.9e-14 52.5 1.9 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding DNA_pol3_a_NI PF14480.6 OEU08447.1 - 0.042 13.8 0.3 0.14 12.2 0.3 1.8 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I FGE-sulfatase PF03781.16 OEU08449.1 - 4e-26 92.2 3.5 7e-26 91.4 3.5 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.6 OEU08449.1 - 2.5e-12 46.9 0.0 4.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU08449.1 - 7.2e-08 32.4 0.0 7.5e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU08449.1 - 1.4e-07 32.2 0.0 4.7e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU08449.1 - 2.1e-07 31.6 0.0 1.9e-05 25.3 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU08449.1 - 4.3e-07 30.5 0.0 5.7e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 OEU08449.1 - 5.3e-05 23.7 1.8 7.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 DinB superfamily DREV PF05219.12 OEU08449.1 - 0.0054 15.9 0.0 0.57 9.2 0.0 2.3 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 OEU08449.1 - 0.046 13.0 0.1 0.37 10.1 0.1 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OEU08449.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SR-25 PF10500.9 OEU08450.1 - 0.0042 16.7 12.5 0.0042 16.7 12.5 4.3 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Metallophos PF00149.28 OEU08451.1 - 3.6e-24 86.4 0.2 4.9e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IMS PF00817.20 OEU08452.1 - 3.4e-29 101.8 0.1 8.8e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 OEU08452.1 - 2.4e-08 34.7 0.4 2.2e-07 31.6 0.1 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OEU08452.1 - 0.13 12.7 0.1 0.36 11.3 0.1 1.7 1 0 0 1 1 1 0 IMS family HHH motif SUIM_assoc PF16619.5 OEU08452.1 - 2.6 8.2 7.4 0.62 10.2 0.2 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ATG22 PF11700.8 OEU08453.1 - 1.6e-17 63.3 33.2 1.2e-15 57.2 33.2 2.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OEU08453.1 - 6.1e-08 32.0 29.4 6.1e-08 32.0 29.4 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily QCR10 PF09796.9 OEU08453.1 - 4.5 7.4 5.7 23 5.1 0.0 3.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3464 PF11947.8 OEU08454.1 - 5.8e-32 110.5 1.7 7.1e-32 110.2 0.1 1.7 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 DUF4199 PF13858.6 OEU08454.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PPR_2 PF13041.6 OEU08455.1 - 9.7e-43 144.1 9.3 4.6e-11 42.7 0.1 9.8 8 2 2 10 10 10 8 PPR repeat family PPR_1 PF12854.7 OEU08455.1 - 1.4e-41 139.9 0.7 3.3e-06 26.7 0.0 11.4 11 1 0 11 11 11 9 PPR repeat PPR PF01535.20 OEU08455.1 - 1.3e-33 112.8 14.1 2.5e-06 27.4 0.0 12.3 11 2 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 OEU08455.1 - 2.2e-26 91.7 7.0 0.00017 21.6 0.0 8.8 8 3 2 11 11 10 7 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU08455.1 - 2e-13 50.2 4.6 4.3e-05 23.0 0.3 5.8 4 2 0 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OEU08455.1 - 3.9e-07 30.3 4.7 0.54 11.2 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat Vps39_1 PF10366.9 OEU08455.1 - 1.3e-05 25.4 6.4 3.2 8.1 0.1 5.3 4 1 1 5 5 5 3 Vacuolar sorting protein 39 domain 1 TPR_19 PF14559.6 OEU08455.1 - 0.00022 21.7 10.3 0.46 11.0 0.1 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat Clathrin PF00637.20 OEU08455.1 - 0.00055 19.8 4.1 3.2 7.6 0.0 4.6 4 0 0 4 4 4 1 Region in Clathrin and VPS TPR_1 PF00515.28 OEU08455.1 - 0.0025 17.6 0.9 1.8 8.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OEU08455.1 - 0.018 15.0 0.4 7.1 6.5 0.0 3.9 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_2 PF07719.17 OEU08455.1 - 0.04 14.0 3.5 1.1 9.5 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU08455.1 - 0.075 12.4 7.1 17 4.7 0.0 4.3 3 1 1 5 5 5 0 MalT-like TPR region TPR_7 PF13176.6 OEU08455.1 - 0.14 12.2 2.6 12 6.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat IDH PF03971.14 OEU08456.1 - 0 1145.6 0.0 0 1145.4 0.0 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase Alg6_Alg8 PF03155.15 OEU08457.1 - 1.9e-93 314.1 10.3 2.8e-50 171.7 1.9 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family PHD PF00628.29 OEU08458.1 - 2.3e-13 49.8 10.4 2.6e-13 49.6 10.4 1.0 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OEU08458.1 - 3.5e-05 23.5 0.9 3.5e-05 23.5 0.9 1.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 OEU08458.1 - 0.00067 19.2 5.2 0.00067 19.2 5.2 1.8 2 0 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 OEU08458.1 - 0.0028 17.8 2.8 0.0028 17.8 2.8 1.8 1 1 1 2 2 2 1 KIAA1045 RING finger zf-RING_2 PF13639.6 OEU08458.1 - 0.0071 16.7 9.8 0.0093 16.3 9.8 1.2 1 0 0 1 1 1 1 Ring finger domain NHL PF01436.21 OEU08458.1 - 0.024 14.7 0.2 0.048 13.7 0.2 1.5 1 1 0 1 1 1 0 NHL repeat zf-ANAPC11 PF12861.7 OEU08458.1 - 0.29 11.2 7.9 0.86 9.7 7.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 OEU08458.1 - 0.39 11.0 8.1 0.49 10.7 8.1 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_4 PF16866.5 OEU08458.1 - 5.7 7.1 14.9 1.2 9.2 8.9 2.3 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 OEU08458.1 - 5.9 6.9 14.9 0.25 11.3 7.0 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OEU08459.1 - 1.1e-11 44.4 4.5 1.5e-11 44.0 4.5 1.2 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OEU08459.1 - 0.00014 21.5 1.3 0.00022 20.9 1.3 1.2 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 OEU08459.1 - 0.0011 19.1 0.5 0.0015 18.6 0.5 1.3 1 0 0 1 1 1 1 KIAA1045 RING finger zf-HC5HC2H PF13771.6 OEU08459.1 - 0.0018 18.5 0.1 0.0019 18.4 0.1 1.2 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OEU08459.1 - 0.0066 16.6 0.1 0.008 16.3 0.1 1.1 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD_2 PF13831.6 OEU08459.1 - 0.0076 15.8 0.9 0.0076 15.8 0.9 1.8 2 0 0 2 2 2 1 PHD-finger NHL PF01436.21 OEU08459.1 - 0.07 13.2 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 NHL repeat zf-RING_2 PF13639.6 OEU08459.1 - 0.07 13.5 3.9 0.092 13.1 3.9 1.3 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 OEU08459.1 - 0.074 12.9 3.8 0.16 11.9 3.8 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OEU08459.1 - 0.25 11.3 6.1 0.46 10.5 6.1 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 OEU08460.1 - 5.1e-10 39.5 4.7 5.1e-10 39.5 4.7 2.6 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 OEU08460.1 - 7.7e-10 38.2 0.4 7.7e-10 38.2 0.4 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 OEU08460.1 - 2.7e-07 30.4 4.2 2.7e-07 30.4 4.2 3.9 3 2 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.6 OEU08460.1 - 0.00013 22.2 17.1 0.042 14.1 7.8 3.7 2 1 1 3 3 3 3 PHD-like zinc-binding domain C1_1 PF00130.22 OEU08460.1 - 0.0015 18.4 0.6 0.0015 18.4 0.6 3.4 4 1 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OEU08460.1 - 0.015 15.2 2.8 0.015 15.2 2.8 3.2 3 1 2 5 5 5 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 OEU08460.1 - 1.9 8.9 20.1 0.42 11.0 2.8 3.2 4 0 0 4 4 4 0 C1 domain Pkinase PF00069.25 OEU08461.1 - 1.5e-61 208.1 0.0 1.8e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08461.1 - 2.1e-28 99.3 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU08461.1 - 4.3e-06 25.8 0.0 7.8e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU08461.1 - 6.4e-05 22.4 0.1 0.00039 19.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OEU08461.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Imm7 PF15585.6 OEU08461.1 - 0.012 15.8 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 7 APH PF01636.23 OEU08461.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dickkopf_N PF04706.12 OEU08462.1 - 0.015 15.8 9.8 0.13 12.8 2.0 2.6 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region WAP PF00095.21 OEU08462.1 - 0.12 12.7 11.1 0.72 10.3 2.5 2.4 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' IL17R_fnIII_D1 PF16556.5 OEU08462.1 - 0.13 11.9 0.8 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 DX PF01666.17 OEU08462.1 - 0.19 12.2 7.8 2.9 8.4 1.2 2.4 2 1 0 2 2 2 0 DX module TnpV PF14198.6 OEU08463.1 - 2 8.4 10.7 3.1 7.8 5.3 2.5 2 0 0 2 2 2 0 Transposon-encoded protein TnpV zf-BED PF02892.15 OEU08464.1 - 0.0003 20.7 2.7 0.00058 19.8 0.6 2.6 3 0 0 3 3 3 1 BED zinc finger DUF659 PF04937.15 OEU08464.1 - 0.0003 20.7 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BaffR-Tall_bind PF09256.10 OEU08464.1 - 0.93 9.3 3.3 11 5.8 0.6 2.5 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding BCAS2 PF05700.11 OEU08467.1 - 0.22 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) AAA_22 PF13401.6 OEU08468.1 - 9.4e-08 32.4 0.0 3.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU08468.1 - 9.3e-06 25.7 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 OEU08468.1 - 2e-05 25.0 0.0 4.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 OEU08468.1 - 0.00074 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 OEU08468.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OEU08468.1 - 0.0078 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU08468.1 - 0.0079 15.9 0.0 0.028 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OEU08468.1 - 0.0084 15.8 0.1 0.022 14.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OEU08468.1 - 0.012 15.9 0.2 0.053 13.8 0.1 2.0 1 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OEU08468.1 - 0.013 15.4 0.1 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 OEU08468.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1018 PF06252.12 OEU08468.1 - 0.025 15.5 0.1 0.067 14.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RNA_helicase PF00910.22 OEU08468.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TAF1D PF15333.6 OEU08468.1 - 0.12 12.1 1.1 5.8 6.6 0.1 2.2 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D TrmO PF01980.16 OEU08469.1 - 1.5e-36 125.2 0.0 3.5e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 tRNA-methyltransferase O TrmO_C PF18389.1 OEU08469.1 - 0.037 14.1 0.1 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 TrmO C-terminal domain UCH PF00443.29 OEU08470.1 - 2.1e-11 43.8 0.7 2.5e-11 43.6 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Reo_P9 PF06043.11 OEU08470.1 - 0.078 12.4 0.9 0.085 12.3 0.9 1.1 1 0 0 1 1 1 0 Reovirus P9-like family HD_4 PF13328.6 OEU08470.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 HD domain Presenilin PF01080.17 OEU08470.1 - 0.62 8.8 4.8 0.65 8.7 4.8 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OEU08470.1 - 0.67 8.2 5.8 0.8 7.9 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4175 PF13779.6 OEU08470.1 - 0.81 7.5 7.4 1 7.2 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) XAP5 PF04921.14 OEU08470.1 - 2.1 8.1 7.7 2.5 7.8 7.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Mito_fiss_reg PF05308.11 OEU08470.1 - 6.2 6.8 15.8 0.84 9.7 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 OEU08472.1 - 3.3e-45 154.5 0.0 4.6e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08472.1 - 1.2e-23 83.8 0.0 2.5e-22 79.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU08472.1 - 0.0066 15.8 0.0 0.0094 15.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU08472.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 OEU08472.1 - 0.21 10.5 0.0 0.26 10.2 0.0 1.2 1 1 0 1 1 1 0 Haspin like kinase domain SufE PF02657.15 OEU08474.1 - 1.4e-28 99.2 0.0 2.4e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 OEU08474.1 - 6.7e-16 58.3 0.0 1.9e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 BolA-like protein CENP-Q PF13094.6 OEU08474.1 - 0.21 11.8 2.6 1.8 8.8 3.2 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3340 PF11818.8 OEU08474.1 - 0.52 10.5 5.7 0.071 13.3 1.4 1.7 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) FmdA_AmdA PF03069.15 OEU08475.1 - 5.3e-32 111.1 0.0 3.9e-21 75.4 0.1 3.2 2 1 1 3 3 3 3 Acetamidase/Formamidase family CAP_N PF01213.19 OEU08476.1 - 3 7.2 7.5 4.7 6.6 7.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 2OG-FeII_Oxy_5 PF13759.6 OEU08477.1 - 0.0016 18.8 0.1 0.0045 17.4 0.1 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF2990 PF11693.8 OEU08477.1 - 0.11 12.7 0.1 0.35 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) zf-UBR PF02207.20 OEU08477.1 - 0.45 10.7 12.0 1 9.6 12.0 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) SLS PF14611.6 OEU08478.1 - 0.033 14.0 0.2 0.042 13.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator B277 PF17623.2 OEU08478.1 - 0.27 10.3 0.4 0.38 9.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function Pertus-S5-tox PF09276.10 OEU08479.1 - 0.13 12.3 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Pertussis toxin S5 subunit Ank_2 PF12796.7 OEU08481.1 - 6.1e-13 49.2 0.0 6.1e-07 30.0 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU08481.1 - 5e-10 39.4 0.0 1.4e-07 31.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU08481.1 - 1e-06 28.6 0.1 1.6 9.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OEU08481.1 - 0.0031 17.9 0.1 1.2 9.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OEU08481.1 - 0.15 12.7 0.0 0.62 10.7 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Phosducin PF02114.16 OEU08483.1 - 0.01 14.8 1.3 0.015 14.2 1.3 1.3 1 0 0 1 1 1 0 Phosducin SWIM PF04434.17 OEU08484.1 - 4.3e-05 23.1 0.2 0.0001 21.9 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger C1_1 PF00130.22 OEU08484.1 - 0.0038 17.1 6.9 0.0092 15.9 6.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 OEU08484.1 - 0.53 9.9 6.4 0.46 10.1 4.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 OEU08484.1 - 0.63 10.4 8.0 0.22 11.8 4.4 2.2 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 OEU08485.1 - 3.9e-10 39.5 9.6 8.9e-10 38.3 9.6 1.6 1 1 1 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 OEU08485.1 - 0.0037 17.4 0.5 0.005 17.0 0.5 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OEU08485.1 - 0.0054 16.9 1.0 0.0064 16.7 1.0 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OEU08485.1 - 0.0066 16.0 3.5 0.0066 16.0 3.5 2.1 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 OEU08485.1 - 0.028 14.0 3.5 0.028 14.0 3.5 2.3 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-ANAPC11 PF12861.7 OEU08485.1 - 0.045 13.8 3.5 0.058 13.5 3.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PolC_DP2 PF03833.13 OEU08485.1 - 0.36 8.6 2.8 0.36 8.6 2.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Zf_RING PF16744.5 OEU08485.1 - 0.55 10.4 11.1 2.3 8.4 10.6 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 OEU08485.1 - 2.2 8.7 9.9 0.23 11.8 4.9 2.0 2 0 0 2 2 2 0 C1 domain DUF2470 PF10615.9 OEU08486.1 - 0.0033 18.0 0.0 0.0056 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Cation_ATPase_C PF00689.21 OEU08489.1 - 0.89 9.2 11.7 1.5 8.5 11.7 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF1772 PF08592.11 OEU08489.1 - 2.8 8.2 5.4 8.9 6.6 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) PhoLip_ATPase_C PF16212.5 OEU08489.1 - 4.9 6.8 14.4 5.2 6.7 13.4 1.6 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF2142 PF09913.9 OEU08489.1 - 6.6 5.5 13.5 0.6 8.9 7.3 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) SNO PF01174.19 OEU08491.1 - 0.05 13.4 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DUF905 PF06006.12 OEU08491.1 - 0.37 10.8 1.4 0.86 9.6 1.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF905) NIF PF03031.18 OEU08492.1 - 8.1e-11 41.9 4.2 1.6e-10 41.0 0.1 2.9 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Cwf_Cwc_15 PF04889.12 OEU08492.1 - 2 8.1 31.2 0.32 10.7 3.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 OEU08492.1 - 6.4 5.3 12.1 13 4.3 12.1 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CW PF07496.15 OEU08493.1 - 6.1e-09 35.8 5.9 6.1e-09 35.8 5.9 3.1 3 0 0 3 3 3 1 CW-type Zinc Finger POPLD PF08170.12 OEU08493.1 - 0.12 12.8 4.9 2.3 8.6 0.4 2.8 2 0 0 2 2 2 0 POPLD (NUC188) domain DUF775 PF05603.12 OEU08493.1 - 1.3 8.5 5.9 0.31 10.5 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF775) Terminase_4 PF05119.12 OEU08494.1 - 0.17 12.3 0.9 7.2 7.1 0.1 2.1 2 0 0 2 2 2 0 Phage terminase, small subunit Arylsulfotran_N PF17425.2 OEU08494.1 - 0.36 10.9 6.5 6.2 6.9 0.5 2.3 2 0 0 2 2 2 0 Arylsulfotransferase Ig-like domain Syndecan PF01034.20 OEU08494.1 - 1.3 9.0 4.3 15 5.6 0.1 2.3 2 0 0 2 2 2 0 Syndecan domain Methyltransf_21 PF05050.12 OEU08495.1 - 1.9e-07 31.3 0.0 2.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Nucleoporin_FG PF13634.6 OEU08496.1 - 0.0015 19.3 15.7 0.024 15.5 12.1 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region Laminin_G_2 PF02210.24 OEU08496.1 - 0.3 11.7 11.2 2.4e+03 -0.9 11.2 3.2 1 1 0 1 1 1 0 Laminin G domain DUF2206 PF09971.9 OEU08497.1 - 0.00012 21.0 0.1 0.00019 20.3 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) HhH-GPD PF00730.25 OEU08497.1 - 0.0008 19.8 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Synapsin PF02078.16 OEU08497.1 - 0.13 12.5 2.1 0.21 11.9 0.1 2.2 2 0 0 2 2 2 0 Synapsin, N-terminal domain GIY-YIG PF01541.24 OEU08497.1 - 1.1 9.6 7.6 5.1 7.5 0.4 2.8 2 0 0 2 2 2 0 GIY-YIG catalytic domain DoxX_2 PF13564.6 OEU08498.1 - 0.0031 17.6 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 DoxX-like family Otopetrin PF03189.13 OEU08499.1 - 0.007 15.2 0.0 0.013 14.4 0.0 1.4 1 1 0 1 1 1 1 Otopetrin Hydin_ADK PF17213.3 OEU08499.1 - 0.0079 16.5 1.4 0.0079 16.5 1.4 2.1 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Viral_Beta_CD PF04530.12 OEU08499.1 - 0.0081 16.5 0.1 0.021 15.2 0.1 1.7 1 0 0 1 1 1 1 Viral Beta C/D like family Band_3_cyto PF07565.13 OEU08499.1 - 0.026 14.3 6.9 0.31 10.8 2.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FmiP_Thoc5 PF09766.9 OEU08499.1 - 1.2 8.3 17.6 0.017 14.4 2.1 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF702 PF05142.12 OEU08499.1 - 1.3 9.5 9.2 2.1 8.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) EPL1 PF10513.9 OEU08499.1 - 1.9 8.9 15.0 0.75 10.2 1.9 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF3439 PF11921.8 OEU08499.1 - 2.1 8.3 13.5 2.1 8.3 7.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LAT2 PF15703.5 OEU08499.1 - 4.3 7.2 14.6 0.13 12.1 5.9 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells family member 2 Acetyltransf_2 PF00797.17 OEU08501.1 - 5.1e-22 78.8 0.0 1.7e-17 64.0 0.0 2.4 2 1 0 2 2 2 2 N-acetyltransferase VDE PF07137.11 OEU08502.1 - 4.2e-66 222.9 0.1 5.8e-66 222.4 0.1 1.2 1 0 0 1 1 1 1 VDE lipocalin domain E1-E2_ATPase PF00122.20 OEU08503.1 - 6e-50 169.3 1.0 1.4e-49 168.1 1.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OEU08503.1 - 1.6e-42 145.3 0.2 3.4e-42 144.2 0.2 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OEU08503.1 - 1.2e-20 74.7 0.3 6.7e-09 36.3 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU08503.1 - 4e-14 52.5 0.0 1.9e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OEU08503.1 - 0.00011 22.1 2.7 0.00026 20.8 2.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HA PF03457.14 OEU08504.1 - 6e-07 29.7 0.0 6e-07 29.7 0.0 4.0 5 0 0 5 5 5 1 Helicase associated domain HA PF03457.14 OEU08505.1 - 1.4e-34 118.3 3.4 2.1e-16 60.0 0.7 2.0 2 0 0 2 2 2 2 Helicase associated domain Importin_rep_4 PF18808.1 OEU08506.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.5 2 0 0 2 2 2 0 Importin repeat HSF_DNA-bind PF00447.17 OEU08507.1 - 2.4e-23 82.6 0.3 4.4e-23 81.7 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Baculo_RING PF05883.11 OEU08507.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FSA_C PF10479.9 OEU08507.1 - 0.35 8.9 7.3 0.46 8.5 7.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3439 PF11921.8 OEU08507.1 - 9.6 6.2 10.3 19 5.2 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 OEU08508.1 - 4e-20 72.3 0.0 4.4e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08508.1 - 9.4e-14 51.3 0.0 1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase MaAIMP_sms PF16951.5 OEU08508.1 - 0.22 11.3 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit Fasciclin PF02469.22 OEU08509.1 - 5.8e-14 52.4 0.3 1.5e-12 47.9 0.3 2.4 1 1 0 1 1 1 1 Fasciclin domain NOP19 PF10863.8 OEU08509.1 - 0.035 13.9 1.0 0.088 12.6 1.0 1.6 1 0 0 1 1 1 0 Nucleolar protein 19 MobB PF03205.14 OEU08511.1 - 0.051 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ACC_epsilon PF13822.6 OEU08512.1 - 1 10.1 5.1 0.36 11.6 0.4 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit AP2 PF00847.20 OEU08514.1 - 0.022 15.0 0.3 0.022 15.0 0.3 2.3 2 0 0 2 2 2 0 AP2 domain DNA_pol_B_exo1 PF03104.19 OEU08519.1 - 0.0016 17.7 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain UPF0242 PF06785.11 OEU08521.1 - 0.012 15.7 20.6 0.016 15.3 20.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OEU08521.1 - 0.059 12.4 12.1 0.1 11.7 12.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 OEU08521.1 - 0.065 13.0 25.6 0.092 12.5 25.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family VSG_B PF13206.6 OEU08521.1 - 0.082 12.1 5.9 0.13 11.5 5.9 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF812 PF05667.11 OEU08521.1 - 0.31 9.9 17.6 0.42 9.4 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF5133 PF17196.4 OEU08521.1 - 5.1 7.4 5.0 16 5.8 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF5133) Tudor_3 PF18115.1 OEU08522.1 - 0.022 14.6 0.5 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain YL1 PF05764.13 OEU08522.1 - 9.5 6.3 37.2 1.5 8.9 28.5 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF1966 PF09260.11 OEU08523.1 - 0.026 14.8 0.6 22 5.4 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1966) DUF2779 PF11074.8 OEU08525.1 - 4.5e-24 85.3 7.4 3.4e-23 82.5 2.3 3.4 2 1 0 2 2 2 1 Domain of unknown function(DUF2779) Cas_Cas4 PF01930.17 OEU08525.1 - 0.21 11.7 17.6 0.015 15.4 7.7 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF83 Ferlin_C PF16165.5 OEU08525.1 - 0.47 10.4 4.6 1.5 8.7 4.6 1.9 1 0 0 1 1 1 0 Ferlin C-terminus DUF2681 PF10883.8 OEU08526.1 - 0.0073 16.7 0.7 0.0073 16.7 0.7 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2681) Pox_A_type_inc PF04508.12 OEU08526.1 - 0.014 15.2 18.3 0.21 11.5 1.3 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat WDCP PF15390.6 OEU08526.1 - 0.1 10.9 15.6 0.12 10.7 15.6 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ATP_bind_2 PF03668.15 OEU08526.1 - 3 7.1 6.8 0.3 10.3 2.6 1.5 2 0 0 2 2 2 0 P-loop ATPase protein family DUF3226 PF11536.8 OEU08527.1 - 0.035 13.8 0.5 0.064 12.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Toluene_X PF03349.16 OEU08527.1 - 0.086 11.4 0.0 1.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) PHD_2 PF13831.6 OEU08529.1 - 1.2e-05 24.7 8.2 4.8e-05 22.8 8.2 2.1 1 0 0 1 1 1 1 PHD-finger Tudor_3 PF18115.1 OEU08529.1 - 0.00021 21.1 0.1 0.0006 19.6 0.1 1.9 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 OEU08529.1 - 0.00062 19.4 0.8 0.0016 18.1 0.8 1.8 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 OEU08529.1 - 0.0015 18.3 1.7 0.0031 17.3 1.7 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PHD PF00628.29 OEU08529.1 - 0.0078 16.1 9.8 0.0078 16.1 9.8 3.1 2 1 1 3 3 3 1 PHD-finger B2-adapt-app_C PF09066.10 OEU08529.1 - 0.023 14.8 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain UvsW PF11637.8 OEU08529.1 - 0.056 13.5 1.4 0.18 11.9 1.4 1.9 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW Spt5_N PF11942.8 OEU08529.1 - 2.8 9.0 16.1 0.26 12.3 1.8 4.2 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 OEU08530.1 - 1.7 9.1 4.8 2.4 8.6 4.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_UL1 PF05259.11 OEU08531.1 - 0.094 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus glycoprotein L PT PF04886.12 OEU08532.1 - 0.025 14.1 2.7 0.026 14.1 0.6 2.1 2 0 0 2 2 2 0 PT repeat Cdh1_DBD_1 PF18196.1 OEU08532.1 - 0.034 14.5 0.3 0.087 13.1 0.3 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 LRR_6 PF13516.6 OEU08533.1 - 0.0003 20.6 4.9 0.029 14.4 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LIP1 PF15904.5 OEU08533.1 - 2.2 8.7 6.2 1.4 9.3 1.0 2.6 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 GMC_oxred_N PF00732.19 OEU08535.1 - 3.2e-41 141.6 0.0 4.4e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OEU08535.1 - 2.1e-28 99.7 0.0 3.1e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OEU08535.1 - 0.00052 19.2 0.2 0.00085 18.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OEU08535.1 - 0.0064 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OEU08535.1 - 0.021 15.0 0.0 0.068 13.4 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU08535.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding CRAL_TRIO PF00650.20 OEU08536.1 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Tri3 PF07428.11 OEU08536.1 - 0.072 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 EnY2 PF10163.9 OEU08536.1 - 0.11 12.9 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Transcription factor e(y)2 AAA_33 PF13671.6 OEU08537.1 - 0.00059 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU08537.1 - 0.001 19.3 0.1 0.0078 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OEU08537.1 - 0.009 16.5 5.8 0.99 9.9 0.0 3.5 3 1 1 4 4 4 2 ABC transporter TniB PF05621.11 OEU08537.1 - 0.023 14.1 0.0 6.1 6.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein CTU2 PF10288.9 OEU08537.1 - 0.23 11.7 15.6 0.43 10.8 0.5 4.3 4 1 0 4 4 4 0 Cytoplasmic tRNA 2-thiolation protein 2 Ras PF00071.22 OEU08538.1 - 7.7e-61 204.4 0.2 9e-61 204.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU08538.1 - 4.4e-36 123.7 0.1 6.6e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU08538.1 - 8e-16 58.0 0.1 1e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU08538.1 - 3.4e-07 30.4 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU08538.1 - 9e-06 25.4 0.1 3.2e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU08538.1 - 1.2e-05 25.3 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OEU08538.1 - 0.001 18.6 0.2 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OEU08538.1 - 0.0014 18.1 0.1 0.0021 17.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OEU08538.1 - 0.0016 18.7 0.0 0.014 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU08538.1 - 0.0019 18.6 0.1 0.0033 17.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OEU08538.1 - 0.0069 16.1 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OEU08538.1 - 0.018 14.8 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OEU08538.1 - 0.018 15.5 0.2 0.027 15.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 OEU08538.1 - 0.018 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SRPRB PF09439.10 OEU08538.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OEU08538.1 - 0.032 14.3 0.1 0.1 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OEU08538.1 - 0.039 13.4 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein YtzH PF14165.6 OEU08538.1 - 0.073 13.5 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 YtzH-like protein Ploopntkinase3 PF18751.1 OEU08538.1 - 0.085 12.8 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MCM PF00493.23 OEU08538.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 OEU08538.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.6 1 1 0 1 1 1 0 NTPase zf-RING_2 PF13639.6 OEU08539.1 - 3.2e-07 30.6 2.9 6.5e-07 29.6 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OEU08539.1 - 5.9e-06 26.4 4.8 1.3e-05 25.2 4.8 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 OEU08539.1 - 0.00026 21.2 1.8 0.00066 19.9 1.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU08539.1 - 0.00031 20.5 4.0 0.00066 19.5 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU08539.1 - 0.00094 18.9 4.4 0.002 17.8 4.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_1 PF14446.6 OEU08539.1 - 0.004 17.0 0.7 0.004 17.0 0.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Tmpp129 PF10272.9 OEU08539.1 - 0.0078 15.6 0.8 0.0078 15.6 0.8 1.6 2 0 0 2 2 2 1 Putative transmembrane protein precursor zf-RING_UBOX PF13445.6 OEU08539.1 - 0.0083 16.1 1.3 0.013 15.5 0.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU08539.1 - 0.018 14.9 0.8 0.018 14.9 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU08539.1 - 0.023 14.6 3.1 0.055 13.4 3.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU08539.1 - 0.082 12.8 5.4 0.19 11.6 5.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU08539.1 - 0.092 12.8 2.4 0.44 10.6 2.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OEU08539.1 - 0.13 11.9 0.7 0.35 10.5 0.7 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Cellsynth_D PF03500.13 OEU08540.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Cellulose synthase subunit D Corazonin PF17308.2 OEU08540.1 - 4.1 7.8 12.5 0.89 9.9 1.6 3.6 3 0 0 3 3 3 0 Pro-corazonin DUF423 PF04241.15 OEU08541.1 - 1.2 9.3 8.8 0.061 13.5 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF4396 PF14342.6 OEU08542.1 - 0.017 15.5 0.2 12 6.3 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4396) IGPD PF00475.18 OEU08542.1 - 0.017 15.4 6.6 35 4.7 0.3 5.2 3 1 1 4 4 4 0 Imidazoleglycerol-phosphate dehydratase RP1-2 PF12042.8 OEU08542.1 - 0.023 14.6 2.4 2.8 7.8 0.0 3.1 3 0 0 3 3 3 0 Tubuliform egg casing silk strands structural domain Yae1_N PF09811.9 OEU08542.1 - 0.025 14.3 2.3 87 2.9 0.0 5.3 5 1 1 6 6 6 0 Essential protein Yae1, N terminal Nuc_rec_co-act PF08815.10 OEU08542.1 - 0.092 12.6 0.1 23 4.9 0.0 2.7 2 0 0 2 2 2 0 Nuclear receptor coactivator KRTAP7 PF15034.6 OEU08542.1 - 0.23 12.4 0.2 2.1e+02 2.9 0.0 3.5 1 1 1 3 3 3 0 KRTAP type 7 family Rick_17kDa_Anti PF05433.15 OEU08542.1 - 0.91 9.4 15.0 9.2 6.2 0.2 5.1 4 1 1 5 5 5 0 Glycine zipper 2TM domain DUF2148 PF09918.9 OEU08542.1 - 0.95 9.5 3.9 99 3.1 0.0 4.4 4 1 1 5 5 5 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) DUF3806 PF12713.7 OEU08542.1 - 1.8 8.4 6.8 62 3.5 0.1 5.1 4 2 2 6 6 6 0 Domain of unknown function (DUF3806) DUF456 PF04306.13 OEU08542.1 - 3.2 8.1 13.1 15 5.8 7.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF456) CSD PF00313.22 OEU08543.1 - 1.6e-06 27.9 3.6 4.3e-06 26.5 3.6 1.8 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU08543.1 - 0.0027 17.3 1.5 0.02 14.6 0.2 2.5 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF445 PF04286.12 OEU08544.1 - 9.5e-16 58.6 3.2 1.6e-06 28.2 0.2 4.5 3 2 1 4 4 4 3 Protein of unknown function (DUF445) SPC12 PF06645.13 OEU08544.1 - 0.99 9.5 4.1 54 4.0 0.0 3.1 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) UPRTase PF14681.6 OEU08545.1 - 0.051 13.0 1.6 0.1 12.0 1.6 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Coilin_N PF15862.5 OEU08545.1 - 1.1 9.1 0.0 1.1 9.1 0.0 4.4 3 2 2 6 6 6 0 Coilin N-terminus DUF285 PF03382.14 OEU08546.1 - 1.9e-115 379.5 77.8 7.7e-34 116.1 11.3 4.2 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DUF1108 PF06531.11 OEU08546.1 - 0.0063 16.8 7.9 1.1e+02 3.2 0.0 6.8 3 1 5 8 8 8 0 Protein of unknown function (DUF1108) FTH PF01827.27 OEU08546.1 - 0.024 14.4 6.1 10 5.9 0.1 3.6 4 0 0 4 4 4 0 FTH domain MT PF12777.7 OEU08548.1 - 1.6e-17 63.6 0.1 1.8e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF3226 PF11536.8 OEU08548.1 - 0.049 13.3 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) PT PF04886.12 OEU08549.1 - 2.2e-13 49.5 13.7 0.0024 17.4 13.7 3.2 1 1 0 1 1 1 1 PT repeat PLN_propep PF16485.5 OEU08550.1 - 0.014 15.1 0.5 8.2 6.2 0.0 2.5 2 1 0 2 2 2 0 Protealysin propeptide Papilloma_E5A PF05776.12 OEU08551.1 - 0.012 16.0 2.5 0.012 16.0 2.5 2.2 2 0 0 2 2 2 0 Papillomavirus E5A protein Popeye PF04831.13 OEU08552.1 - 1.5e-08 34.9 0.0 1.9e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 OEU08552.1 - 0.00015 21.7 0.0 0.00044 20.3 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Fic PF02661.18 OEU08553.1 - 7.3e-07 30.0 0.1 1.9e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family Secretin_N_2 PF07655.13 OEU08554.1 - 4.1 8.0 16.4 6.6 7.4 0.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Cyclin_N PF00134.23 OEU08555.1 - 1.4e-16 60.4 0.6 1.4e-16 60.4 0.6 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU08555.1 - 3e-08 33.8 0.1 3e-08 33.8 0.1 1.9 2 1 1 3 3 3 1 Cyclin, C-terminal domain GRASP55_65 PF04495.14 OEU08556.1 - 5.8e-45 153.0 0.0 4.6e-36 124.2 0.1 2.1 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 OEU08556.1 - 0.0013 19.0 0.4 0.24 11.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OEU08556.1 - 0.002 17.9 0.1 0.15 11.9 0.0 2.8 3 0 0 3 3 3 1 PDZ domain Ank_5 PF13857.6 OEU08557.1 - 1.2e-10 41.4 0.1 2.4e-05 24.5 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU08557.1 - 1.7e-10 41.2 0.5 3.8e-08 33.7 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU08557.1 - 3.5e-10 40.3 0.0 1.1e-08 35.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU08557.1 - 7.8e-08 32.0 0.0 0.0003 21.0 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OEU08557.1 - 5.2e-05 23.5 0.0 0.022 15.2 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeat Serinc PF03348.15 OEU08557.1 - 0.011 14.7 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Get5_C PF18514.1 OEU08558.1 - 0.15 11.8 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain PT PF04886.12 OEU08559.1 - 0.014 14.9 56.4 1.8e+04 -7.1 56.4 3.2 1 1 0 1 1 1 0 PT repeat AP3D1 PF06375.11 OEU08559.1 - 0.02 15.2 5.4 0.034 14.4 5.4 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Draxin PF15550.6 OEU08559.1 - 0.022 14.6 2.4 0.028 14.3 2.4 1.1 1 0 0 1 1 1 0 Draxin Rib_recp_KP_reg PF05104.12 OEU08559.1 - 0.31 12.1 26.0 0.46 11.5 26.0 1.4 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region Presenilin PF01080.17 OEU08559.1 - 0.76 8.5 2.6 0.79 8.4 2.6 1.1 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 OEU08559.1 - 0.88 9.6 34.3 0.99 9.4 33.5 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein MAP65_ASE1 PF03999.12 OEU08559.1 - 1.8 7.2 11.6 2.1 7.0 11.6 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SpoIIIAH PF12685.7 OEU08559.1 - 2.1 8.1 12.2 5.5 6.8 12.2 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein Hid1 PF12722.7 OEU08559.1 - 2.2 6.3 5.6 2.3 6.2 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AICARFT_IMPCHas PF01808.18 OEU08560.1 - 1.5e-78 264.2 0.5 2e-78 263.9 0.5 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OEU08560.1 - 1.9e-19 69.6 0.0 4.8e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Ank_2 PF12796.7 OEU08561.1 - 0.012 16.2 0.0 0.7 10.5 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU08561.1 - 0.15 12.7 0.2 1.7e+02 3.4 0.0 4.7 5 0 0 5 5 5 0 Ankyrin repeat Secretin_N_2 PF07655.13 OEU08561.1 - 0.7 10.5 6.2 1.2 9.7 6.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain FtsH_ext PF06480.15 OEU08562.1 - 0.061 13.7 0.7 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 FtsH Extracellular Ery_res_leader1 PF08051.11 OEU08562.1 - 0.18 12.0 0.2 4.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Erythromycin resistance leader peptide TFIIE-A_C PF11521.8 OEU08562.1 - 0.53 10.6 5.7 0.21 11.9 1.8 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha ShK PF01549.24 OEU08563.1 - 5.7e-10 39.6 33.9 5.9e-07 29.9 4.3 4.3 4 0 0 4 4 4 3 ShK domain-like DUF1450 PF07293.11 OEU08563.1 - 6.9 6.6 15.1 4.2 7.2 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1450) MFS_1 PF07690.16 OEU08564.1 - 1.1e-26 93.6 22.3 1.1e-26 93.6 22.3 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU08564.1 - 2.1e-07 30.2 18.8 8.4e-07 28.2 18.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 OEU08564.1 - 0.031 12.7 6.1 0.12 10.7 6.1 1.9 1 1 0 1 1 1 0 Transmembrane secretion effector TRI12 PF06609.13 OEU08564.1 - 0.036 12.5 4.5 1.2 7.4 0.8 2.8 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) zf-H2C2 PF09337.10 OEU08565.1 - 0.036 14.3 0.3 0.11 12.7 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger ATP-grasp_3 PF02655.14 OEU08566.1 - 6.1e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OEU08566.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 OEU08566.1 - 0.0025 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon DUF448 PF04296.13 OEU08566.1 - 0.0038 17.0 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF448) PPDK_N PF01326.19 OEU08566.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ATP-grasp PF02222.22 OEU08566.1 - 0.016 14.8 0.0 0.44 10.1 0.0 2.2 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 OEU08566.1 - 0.024 14.1 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Fasciclin PF02469.22 OEU08567.1 - 9.4e-22 77.6 0.0 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF3430 PF11912.8 OEU08567.1 - 1.8e-06 28.1 2.6 3e-06 27.4 2.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) DUF547 PF04784.14 OEU08568.1 - 2.3e-21 76.1 0.0 4.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 7tm_3 PF00003.22 OEU08570.1 - 2.5e-09 37.2 34.9 2.9e-08 33.7 34.9 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR LRR19-TM PF15176.6 OEU08570.1 - 0.074 13.0 3.4 0.13 12.2 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain PDR_CDR PF06422.12 OEU08570.1 - 1.6 8.7 4.1 23 4.9 0.1 3.0 2 0 0 2 2 2 0 CDR ABC transporter AAA_14 PF13173.6 OEU08571.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain CSRNP_N PF16019.5 OEU08572.1 - 7.9e-07 29.2 1.5 1.4e-05 25.2 1.5 2.0 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus SDF PF00375.18 OEU08574.1 - 1.6e-77 261.2 31.6 5.7e-77 259.3 31.6 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Ribosomal_L27 PF01016.19 OEU08575.1 - 8.5e-32 109.0 1.3 9.3e-32 108.9 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Imm48 PF15574.6 OEU08577.1 - 0.42 10.4 4.1 2.9 7.7 2.4 2.4 2 0 0 2 2 2 0 Immunity protein 48 HSP70 PF00012.20 OEU08578.1 - 5.4e-95 318.8 1.6 6e-95 318.7 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OEU08578.1 - 3.6e-12 45.7 1.3 2.7e-09 36.3 0.1 2.1 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OEU08578.1 - 0.04 14.3 2.7 0.13 12.7 0.3 2.2 2 1 0 2 2 2 0 Cell division protein FtsA Hydantoinase_A PF01968.18 OEU08578.1 - 0.046 13.0 3.0 0.082 12.2 0.4 2.2 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase Peptidase_C1 PF00112.23 OEU08579.1 - 2.5e-21 76.8 0.0 7.2e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OEU08579.1 - 0.086 11.6 0.0 0.57 8.9 0.1 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Galactosyl_T PF01762.21 OEU08581.1 - 2.7e-11 43.7 0.0 7.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Galactosyltransferase Ciart PF15673.5 OEU08581.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor Methyltransf_16 PF10294.9 OEU08583.1 - 9.7e-16 58.0 0.7 9.7e-16 58.0 0.7 1.7 2 1 0 2 2 2 1 Lysine methyltransferase HSF_DNA-bind PF00447.17 OEU08584.1 - 2.7e-12 47.1 0.8 1.8e-09 38.1 0.4 2.4 2 0 0 2 2 2 2 HSF-type DNA-binding UPF0257 PF06788.13 OEU08584.1 - 0.11 12.3 2.9 0.16 11.7 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) SR-25 PF10500.9 OEU08584.1 - 0.35 10.5 16.3 0.75 9.4 9.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 OEU08584.1 - 0.5 10.4 11.0 4 7.4 0.5 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein p450 PF00067.22 OEU08585.1 - 1.1e-07 31.0 0.0 0.00037 19.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 OEU08586.1 - 5.2e-21 74.9 0.0 5.9e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 dsrm PF00035.26 OEU08590.1 - 0.00029 21.5 0.9 0.001 19.7 0.9 2.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif Acetyltransf_3 PF13302.7 OEU08591.1 - 0.00017 22.2 0.0 0.00021 22.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GatB_Yqey PF02637.18 OEU08591.1 - 0.12 12.3 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 GatB domain Roughex PF06020.11 OEU08592.1 - 0.11 11.6 6.1 0.13 11.4 6.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Mito_fiss_reg PF05308.11 OEU08593.1 - 1.5 8.8 12.5 6.6 6.7 5.6 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator tRNA_bind PF01588.20 OEU08594.1 - 1.1e-25 89.5 0.1 1.5e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain TMEM40 PF15817.5 OEU08596.1 - 0.17 11.6 8.8 5.5 6.8 6.1 2.6 2 1 0 2 2 2 0 Transmembrane protein 40 family TRAM_LAG1_CLN8 PF03798.16 OEU08596.1 - 0.25 11.1 14.1 0.74 9.5 14.1 1.7 1 1 0 1 1 1 0 TLC domain Acetyltransf_10 PF13673.7 OEU08597.1 - 3.9e-05 23.6 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU08597.1 - 0.0094 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU08597.1 - 0.13 12.7 0.4 0.27 11.7 0.4 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Patched PF02460.18 OEU08601.1 - 4e-31 107.9 21.6 4.9e-31 107.6 21.6 1.0 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.19 OEU08601.1 - 0.0061 14.3 20.0 0.0071 14.1 20.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 OEU08601.1 - 2.5 6.9 26.1 5.5 5.8 26.1 1.5 1 1 0 1 1 1 0 MMPL family SecD_SecF PF02355.16 OEU08601.1 - 5.1 6.4 20.3 15 4.9 20.3 1.7 1 1 0 1 1 1 0 Protein export membrane protein FKBP_C PF00254.28 OEU08602.1 - 6.8e-27 93.6 0.0 8e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ERG4_ERG24 PF01222.17 OEU08604.1 - 3.2e-119 398.5 13.9 3.6e-119 398.4 13.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FixQ PF05545.11 OEU08604.1 - 0.0045 16.9 0.0 0.02 14.9 0.0 2.1 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ DUF1295 PF06966.12 OEU08604.1 - 0.0048 16.5 0.1 0.0088 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PT PF04886.12 OEU08605.1 - 0.017 14.6 14.9 0.017 14.6 14.9 3.0 2 1 0 2 2 2 0 PT repeat SOBP PF15279.6 OEU08605.1 - 0.18 12.4 16.1 0.22 12.1 16.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3494 PF11999.8 OEU08607.1 - 1.8e-27 96.4 8.8 2.2e-27 96.1 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Pirin_C PF05726.13 OEU08607.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 1 0 2 2 2 0 Pirin C-terminal cupin domain OstA PF03968.14 OEU08607.1 - 0.013 15.6 0.6 0.52 10.5 0.1 2.4 2 1 1 3 3 3 0 OstA-like protein Methyltransf_21 PF05050.12 OEU08608.1 - 1.3e-08 35.0 0.0 3.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase FkbM domain Serglycin PF04360.12 OEU08608.1 - 1.1 9.2 5.2 0.17 11.8 0.5 2.0 2 0 0 2 2 2 0 Serglycin Cyclin_N PF00134.23 OEU08610.1 - 3.1e-10 39.9 0.0 9.5e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain Wx5_PLAF3D7 PF09688.10 OEU08611.1 - 1.9 8.5 9.7 0.11 12.6 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) SR-25 PF10500.9 OEU08612.1 - 1.7 8.2 6.1 1.8 8.1 6.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sulfotransfer_2 PF03567.14 OEU08616.1 - 1.7e-07 31.4 1.1 3.8e-07 30.3 1.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.16 OEU08617.1 - 1.2e-24 86.9 37.5 1.2e-24 86.9 37.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HA PF03457.14 OEU08618.1 - 6.7e-51 170.5 1.6 1.9e-17 63.3 0.0 3.5 3 0 0 3 3 3 3 Helicase associated domain Myb_DNA-binding PF00249.31 OEU08618.1 - 7.4e-19 67.7 13.6 1.1e-08 35.1 0.2 4.4 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU08618.1 - 2.5e-16 59.6 10.2 6.5e-06 26.3 1.1 4.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain K_channel_TID PF07941.11 OEU08618.1 - 0.047 14.1 1.1 0.1 13.1 1.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Myb_DNA-bind_7 PF15963.5 OEU08618.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.1 4 0 0 4 4 4 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OEU08618.1 - 0.31 11.4 4.8 6.6 7.1 0.2 3.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HA PF03457.14 OEU08619.1 - 3.4e-62 206.7 11.6 6.3e-21 74.5 0.9 3.0 3 0 0 3 3 3 3 Helicase associated domain DUF5382 PF17354.2 OEU08619.1 - 0.00068 18.6 0.3 0.4 9.5 0.0 2.9 1 1 2 3 3 3 2 Family of unknown function (DUF5382) PMR5N PF14416.6 OEU08619.1 - 0.028 14.7 0.4 25 5.3 0.0 3.5 3 0 0 3 3 3 0 PMR5 N terminal Domain DUF5049 PF16468.5 OEU08619.1 - 0.13 12.2 0.2 7.5 6.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) Chloroa_b-bind PF00504.21 OEU08620.1 - 1.2e-37 129.9 0.0 1.7e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PCIF1_WW PF12237.8 OEU08622.1 - 3.7e-39 134.1 5.5 9.8e-37 126.2 5.5 2.1 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain HSF_DNA-bind PF00447.17 OEU08623.1 - 2.9e-14 53.5 0.0 2.9e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding HA PF03457.14 OEU08624.1 - 7.5e-32 109.5 0.5 1.1e-14 54.5 0.2 2.2 2 0 0 2 2 2 2 Helicase associated domain NDUF_B4 PF07225.12 OEU08624.1 - 0.072 13.0 1.4 0.22 11.4 0.3 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) CRAL_TRIO PF00650.20 OEU08625.1 - 2.3e-15 56.7 0.0 2.5e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU08625.1 - 0.069 13.3 0.1 0.071 13.3 0.1 1.0 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain MCLC PF05934.11 OEU08626.1 - 0.047 12.4 2.6 0.091 11.5 2.6 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3810 PF12725.7 OEU08626.1 - 0.065 12.6 1.8 0.21 10.9 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) HA PF03457.14 OEU08628.1 - 4.4e-89 292.8 9.4 1.5e-17 63.6 0.1 5.2 5 0 0 5 5 5 5 Helicase associated domain DUF3822 PF12864.7 OEU08628.1 - 1.4e-06 27.7 2.7 0.0057 15.9 0.0 3.5 3 1 1 4 4 4 3 Protein of unknown function (DUF3822) ESCRT-II PF05871.12 OEU08629.1 - 3.2e-41 140.9 0.0 3.9e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit OrgA_MxiK PF09482.10 OEU08629.1 - 0.076 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Peptidase_M11 PF05548.11 OEU08630.1 - 1.6e-16 60.4 1.8 1.6e-16 60.4 1.8 1.7 2 0 0 2 2 2 1 Gametolysin peptidase M11 LTD PF00932.19 OEU08630.1 - 5.2e-09 36.4 0.0 3.3e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Lamin Tail Domain Reprolysin_4 PF13583.6 OEU08630.1 - 0.018 14.7 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 OEU08630.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 OEU08630.1 - 0.12 12.8 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU08630.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Matrixin PT PF04886.12 OEU08630.1 - 5.2 6.7 19.3 9.3 5.9 19.3 1.4 1 0 0 1 1 1 0 PT repeat BTB_2 PF02214.22 OEU08631.1 - 3.7e-06 27.2 0.0 1.2e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Coronavirus_5 PF05528.11 OEU08632.1 - 6 6.9 10.2 3.3 7.8 4.6 2.5 1 1 1 2 2 2 0 Coronavirus gene 5 protein LRR_1 PF00560.33 OEU08633.1 - 0.25 12.0 1.9 28 5.8 0.2 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat zf-MYND PF01753.18 OEU08634.1 - 1.5e-07 31.4 13.6 1.5e-07 31.4 13.6 2.3 2 0 0 2 2 2 1 MYND finger HA PF03457.14 OEU08635.1 - 2.9e-52 174.8 7.6 7.1e-17 61.5 0.1 3.0 3 0 0 3 3 3 3 Helicase associated domain Methyltransf_22 PF13383.6 OEU08635.1 - 0.029 14.0 3.3 2 7.9 0.1 2.5 3 0 0 3 3 3 0 Methyltransferase domain NDUF_B4 PF07225.12 OEU08635.1 - 0.039 13.8 3.3 0.22 11.4 0.2 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) eIF3m_C_helix PF18005.1 OEU08635.1 - 0.05 13.3 1.5 11 5.8 0.0 2.9 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix UQ_con PF00179.26 OEU08636.1 - 5.4e-21 74.7 0.0 6e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OEU08636.1 - 0.041 13.7 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain HA PF03457.14 OEU08637.1 - 7.9e-57 189.5 3.6 8.2e-19 67.7 0.0 3.1 3 0 0 3 3 3 3 Helicase associated domain PMR5N PF14416.6 OEU08637.1 - 0.0052 17.1 0.1 17 5.8 0.0 3.5 3 0 0 3 3 3 2 PMR5 N terminal Domain DUF3822 PF12864.7 OEU08637.1 - 0.019 14.2 1.5 0.03 13.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3822) BTB PF00651.31 OEU08638.1 - 1.9e-15 57.0 1.6 3.2e-15 56.3 0.3 1.9 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 OEU08638.1 - 0.00019 21.6 0.0 0.00084 19.5 0.0 2.2 2 1 0 2 2 2 1 MATH domain SAP PF02037.27 OEU08638.1 - 0.0064 16.2 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 SAP domain BACK PF07707.15 OEU08638.1 - 0.036 14.2 0.4 0.098 12.8 0.4 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch GABP-alpha PF11620.8 OEU08638.1 - 0.086 13.0 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain Skp1_POZ PF03931.15 OEU08638.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain SET PF00856.28 OEU08639.1 - 0.00015 22.2 0.1 0.0011 19.3 0.0 2.3 2 1 0 2 2 2 1 SET domain Insulin_TMD PF17870.1 OEU08639.1 - 0.15 12.1 2.1 0.29 11.2 2.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF515 PF04415.12 OEU08639.1 - 6 5.2 9.0 9.2 4.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Glyco_transf_25 PF01755.17 OEU08640.1 - 1.3e-07 31.6 5.8 0.012 15.5 0.1 5.0 3 2 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Tetraspanin PF00335.20 OEU08640.1 - 0.0089 15.8 0.0 0.62 9.7 2.1 2.5 2 2 0 2 2 2 1 Tetraspanin family Mor PF08765.11 OEU08640.1 - 0.069 13.1 1.0 0.27 11.3 1.0 2.0 1 0 0 1 1 1 0 Mor transcription activator family DUF1702 PF08012.11 OEU08640.1 - 0.16 10.8 2.3 0.27 10.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) GTP_EFTU PF00009.27 OEU08641.1 - 0.035 13.7 0.6 0.15 11.6 0.6 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ank_2 PF12796.7 OEU08641.1 - 0.072 13.7 0.0 0.87 10.2 0.0 2.7 3 2 1 4 4 4 0 Ankyrin repeats (3 copies) 2OG-FeII_Oxy_3 PF13640.6 OEU08642.1 - 4.2e-11 43.6 0.2 2.3e-09 38.0 0.2 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 OEU08642.1 - 0.00063 20.2 4.0 0.00063 20.2 4.0 1.9 2 0 0 2 2 2 1 ShK domain-like 2OG-FeII_Oxy_4 PF13661.6 OEU08642.1 - 0.0035 18.0 0.2 0.031 14.9 0.1 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OEU08642.1 - 0.012 16.0 0.1 0.042 14.3 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase EST1 PF10374.9 OEU08642.1 - 0.22 12.1 3.4 0.21 12.2 0.6 2.2 1 1 1 2 2 2 0 Telomerase activating protein Est1 Citrate_bind PF16114.5 OEU08643.1 - 1.5e-79 265.6 0.0 3.2e-79 264.6 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 OEU08643.1 - 2.8e-22 79.3 0.0 1.3e-20 73.8 0.0 2.5 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 OEU08643.1 - 9.8e-14 51.4 0.0 3.7e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_2 PF08442.10 OEU08643.1 - 1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 OEU08643.1 - 2.9e-08 34.3 0.0 7.8e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 OEU08643.1 - 0.0038 17.0 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain HSF_DNA-bind PF00447.17 OEU08644.1 - 6.5e-20 71.6 0.2 7.2e-20 71.4 0.2 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Cas_St_Csn2 PF16813.5 OEU08644.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St PIN_4 PF13638.6 OEU08645.1 - 0.00032 21.0 6.0 0.042 14.1 0.0 3.2 2 1 1 3 3 3 2 PIN domain YL1 PF05764.13 OEU08645.1 - 0.27 11.3 13.4 0.43 10.7 13.4 1.4 1 1 0 1 1 1 0 YL1 nuclear protein TPX2_importin PF12214.8 OEU08645.1 - 2.4 8.3 11.7 8.7 6.5 0.5 2.2 2 0 0 2 2 2 0 Cell cycle regulated microtubule associated protein BTB PF00651.31 OEU08646.1 - 4.3e-13 49.4 1.4 1.9e-12 47.4 0.2 2.3 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 OEU08646.1 - 5e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 MATH domain BACK PF07707.15 OEU08646.1 - 0.0021 18.2 2.0 0.033 14.3 0.1 3.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch SAP PF02037.27 OEU08646.1 - 0.023 14.5 0.0 0.086 12.6 0.0 2.0 1 0 0 1 1 1 0 SAP domain DUF4116 PF13475.6 OEU08647.1 - 5.1e-74 243.8 0.0 2.7e-14 52.6 0.0 7.6 4 2 2 7 7 7 7 Domain of unknown function (DUF4116) DDE_Tnp_IS1595 PF12762.7 OEU08647.1 - 0.03 14.3 1.7 0.86 9.6 0.1 3.2 2 2 2 4 4 4 0 ISXO2-like transposase domain Succ_CoA_lig PF13607.6 OEU08647.1 - 0.083 12.7 7.1 0.35 10.7 0.4 3.7 1 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain YscW PF09619.10 OEU08647.1 - 0.087 13.2 0.3 18 5.7 0.1 2.9 2 1 0 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) DUF2150 PF09920.9 OEU08647.1 - 0.17 11.9 4.6 6.4 6.7 0.3 2.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) S-l_SbsC_C PF18316.1 OEU08647.1 - 1.4 9.5 12.5 11 6.6 1.2 4.8 2 2 3 5 5 5 0 S-layer protein SbsC C-terminal domain LON_substr_bdg PF02190.16 OEU08648.1 - 8.9e-07 29.0 2.7 1.5e-05 24.9 2.7 2.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Macoilin PF09726.9 OEU08648.1 - 0.25 9.8 9.9 0.59 8.6 9.9 1.6 1 0 0 1 1 1 0 Macoilin family mRNA_cap_enzyme PF01331.19 OEU08649.1 - 1.6e-05 24.8 2.8 0.00011 22.1 0.5 3.1 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OEU08649.1 - 0.00086 19.9 0.0 0.003 18.2 0.0 2.0 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain F-box PF00646.33 OEU08649.1 - 0.0019 18.0 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain DUF2922 PF11148.8 OEU08649.1 - 0.12 12.1 0.0 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) UN_NPL4 PF11543.8 OEU08650.1 - 0.0014 19.1 0.9 0.52 10.8 0.1 3.0 3 0 0 3 3 3 2 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 OEU08650.1 - 0.1 12.3 2.6 10 6.0 0.1 3.7 3 1 0 3 3 3 0 Ubiquitin family HA PF03457.14 OEU08651.1 - 9.3e-64 211.7 15.3 3.5e-18 65.7 0.2 4.2 4 0 0 4 4 4 4 Helicase associated domain CDC45 PF02724.14 OEU08651.1 - 0.063 11.6 9.9 0.12 10.6 9.9 1.5 1 0 0 1 1 1 0 CDC45-like protein Lipocalin_7 PF14651.6 OEU08651.1 - 0.14 12.1 1.4 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family MqsR_toxin PF15723.5 OEU08651.1 - 1.1 9.7 5.0 16 5.9 0.7 2.5 1 1 1 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA Spt5_N PF11942.8 OEU08651.1 - 9.9 7.2 17.9 0.34 11.9 10.0 2.5 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Methyltransf_22 PF13383.6 OEU08652.1 - 4.3e-56 190.3 10.9 1.9e-55 188.2 10.9 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OEU08652.1 - 0.0028 17.7 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain MFS_1 PF07690.16 OEU08656.1 - 3.1e-22 79.0 45.4 3.2e-22 79.0 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 OEU08656.1 - 6.3 7.1 8.7 0.87 9.8 0.9 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) PDR_CDR PF06422.12 OEU08656.1 - 9.1 6.3 7.6 5.2 7.0 0.0 3.6 3 0 0 3 3 3 0 CDR ABC transporter MFS_1 PF07690.16 OEU08657.1 - 5.7e-22 78.1 37.4 1.3e-21 76.9 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Prenylcys_lyase PF07156.14 OEU08658.1 - 1.2e-24 87.1 10.0 1.4e-08 34.3 0.3 4.2 3 1 0 4 4 4 4 Prenylcysteine lyase DUF1295 PF06966.12 OEU08660.1 - 1e-23 84.1 2.4 1.4e-23 83.6 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OEU08660.1 - 0.02 14.9 1.9 0.058 13.4 1.9 1.9 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OEU08660.1 - 0.077 13.4 0.1 0.23 11.9 0.1 2.0 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Phage_holin_2_4 PF16082.5 OEU08660.1 - 0.24 11.1 0.9 0.52 10.1 0.9 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Lipl32 PF12103.8 OEU08661.1 - 1.4 8.6 5.8 2 8.0 0.1 2.9 2 1 1 3 3 3 0 Surface lipoprotein of Spirochaetales order FAM75 PF14650.6 OEU08662.1 - 0.077 12.5 0.9 0.1 12.1 0.3 1.5 2 0 0 2 2 2 0 FAM75 family SCAI PF12070.8 OEU08663.1 - 0.011 14.6 0.5 0.015 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein SCAI Microtub_bind PF13931.6 OEU08663.1 - 1.7 9.0 5.5 2.2 8.7 4.7 1.6 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding TFIIA PF03153.13 OEU08664.1 - 0.11 12.5 26.4 0.18 11.8 26.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4448 PF14610.6 OEU08664.1 - 1.3 8.8 5.1 3.4 7.4 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AARP2CN PF08142.12 OEU08664.1 - 1.5 8.9 8.8 0.18 11.9 3.3 2.4 2 1 0 2 2 2 0 AARP2CN (NUC121) domain TPR_2 PF07719.17 OEU08665.1 - 0.0074 16.3 0.6 0.0074 16.3 0.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU08665.1 - 0.0087 15.9 0.5 0.024 14.4 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat BRF1 PF07741.13 OEU08665.1 - 0.011 16.0 11.1 0.48 10.8 0.1 3.5 3 0 0 3 3 3 0 Brf1-like TBP-binding domain TPR_8 PF13181.6 OEU08665.1 - 0.018 15.2 0.1 0.073 13.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TERB2 PF15101.6 OEU08665.1 - 0.024 14.7 0.4 0.024 14.7 0.4 3.4 2 1 1 3 3 3 0 Telomere-associated protein TERB2 TPR_7 PF13176.6 OEU08665.1 - 0.072 13.2 0.7 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2417 PF10329.9 OEU08665.1 - 1.7 8.0 5.5 12 5.2 1.8 2.5 2 1 0 2 2 2 0 Region of unknown function (DUF2417) Plant_zn_clust PF10533.9 OEU08665.1 - 1.9 8.5 8.1 9.4 6.3 0.0 3.7 2 0 0 2 2 2 0 Plant zinc cluster domain DUF608 PF04685.13 OEU08666.1 - 2.7e-23 82.8 0.2 5.3e-23 81.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 OEU08666.1 - 6.7e-22 78.4 16.4 1.5e-19 70.7 16.4 3.2 1 1 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Prominin PF05478.11 OEU08667.1 - 0.061 11.3 1.4 0.074 11.0 1.4 1.1 1 0 0 1 1 1 0 Prominin 3-dmu-9_3-mt PF06983.13 OEU08667.1 - 0.089 13.3 0.2 0.14 12.7 0.2 1.4 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase DUF1690 PF07956.11 OEU08667.1 - 0.21 12.0 6.9 0.078 13.4 3.4 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) YojJ PF10372.9 OEU08667.1 - 0.22 11.6 2.0 11 6.2 0.3 2.7 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus CENP-H PF05837.12 OEU08667.1 - 1.8 9.0 11.3 0.53 10.7 7.8 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Ribosomal_L7Ae PF01248.26 OEU08668.1 - 4.8e-24 83.9 0.3 7.2e-24 83.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LRS4 PF10422.9 OEU08669.1 - 0.048 13.2 0.3 0.053 13.1 0.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Nop14 PF04147.12 OEU08670.1 - 0.24 9.6 16.7 0.22 9.7 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OEU08670.1 - 0.25 10.7 16.2 0.26 10.7 16.2 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 OEU08670.1 - 0.35 10.9 15.9 0.43 10.7 15.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OEU08670.1 - 0.49 8.6 14.0 0.5 8.6 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OEU08670.1 - 0.68 8.0 21.2 0.75 7.8 21.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 OEU08670.1 - 0.85 9.3 7.9 1.3 8.7 7.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Roughex PF06020.11 OEU08670.1 - 2.3 7.3 9.5 2.2 7.3 9.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TRAP_alpha PF03896.16 OEU08670.1 - 2.9 7.0 8.3 3.4 6.8 8.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.9 OEU08670.1 - 6.3 5.8 23.9 8.2 5.4 23.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 OEU08670.1 - 8.6 5.9 16.4 12 5.4 16.4 1.3 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 OEU08670.1 - 9.8 4.6 13.3 10 4.5 13.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AIRC PF00731.20 OEU08671.1 - 0.11 12.1 0.4 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 AIR carboxylase PBP1_TM PF14812.6 OEU08671.1 - 0.76 10.2 4.0 1.7 9.1 4.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_6 PF08030.12 OEU08672.1 - 0.051 13.7 0.1 2 8.5 0.0 2.5 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Ost5 PF05251.12 OEU08672.1 - 0.09 13.0 0.5 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 BSP_II PF05432.11 OEU08672.1 - 0.49 10.0 11.1 0.74 9.5 11.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Lig_chan PF00060.26 OEU08673.1 - 2.2e-15 56.8 0.0 3.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Ion_trans_2 PF07885.16 OEU08673.1 - 0.37 10.8 8.3 0.041 13.8 1.6 2.4 2 0 0 2 2 2 0 Ion channel Phage_holin_2_1 PF04971.12 OEU08673.1 - 5.1 7.2 6.6 2.9 8.0 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage P21 holin S Ank_2 PF12796.7 OEU08675.1 - 4.9e-08 33.4 0.3 0.029 15.0 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU08675.1 - 9e-05 22.7 4.1 4.2 8.0 0.0 5.3 6 1 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OEU08675.1 - 9.5e-05 22.9 0.2 0.0064 17.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU08675.1 - 0.00032 20.9 0.2 14 6.7 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OEU08675.1 - 0.0073 16.6 2.7 28 5.2 0.0 5.2 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Gemini_AL2 PF01440.16 OEU08675.1 - 0.013 15.9 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 Geminivirus AL2 protein HTH_24 PF13412.6 OEU08675.1 - 0.055 13.0 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Arm PF00514.23 OEU08675.1 - 0.084 12.9 2.0 0.43 10.7 0.3 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PseudoU_synth_2 PF00849.22 OEU08677.1 - 4.6e-15 56.1 0.7 4.6e-15 56.1 0.7 2.5 2 1 0 2 2 2 1 RNA pseudouridylate synthase SUIM_assoc PF16619.5 OEU08677.1 - 3.4 7.8 13.0 10 6.3 7.8 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HAD_2 PF13419.6 OEU08678.1 - 2e-14 54.1 0.0 2.3e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU08678.1 - 2e-11 44.6 0.0 6.9e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU08678.1 - 0.0008 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OEU08678.1 - 0.0073 16.7 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Orthopox_A5L PF06193.11 OEU08678.1 - 0.071 12.5 0.5 0.1 12.0 0.5 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF2000 PF09391.10 OEU08679.1 - 0.00028 20.8 3.8 5.3 7.0 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2000) GTPase_binding PF09027.10 OEU08679.1 - 0.14 12.1 1.0 1.2e+02 2.7 0.0 3.8 3 3 2 5 5 5 0 GTPase binding Pardaxin PF07425.11 OEU08679.1 - 1.9 8.2 6.1 76 3.0 0.1 3.6 3 0 0 3 3 3 0 Pardaxin DUF1622 PF07784.11 OEU08679.1 - 4.3 7.3 15.3 14 5.7 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1622) RVT_2 PF07727.14 OEU08680.1 - 0.0024 17.6 0.1 0.0027 17.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM180 PF15173.6 OEU08682.1 - 0.041 13.9 0.1 0.087 12.8 0.0 1.5 2 0 0 2 2 2 0 FAM180 family DUF5552 PF17706.1 OEU08682.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5552) FAM176 PF14851.6 OEU08683.1 - 0.00093 18.9 2.4 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 FAM176 family MARVEL PF01284.23 OEU08683.1 - 0.0086 16.1 9.4 0.25 11.4 0.1 2.9 2 1 0 2 2 2 2 Membrane-associating domain Pex14_N PF04695.13 OEU08683.1 - 0.049 14.3 0.1 7.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TRAP_alpha PF03896.16 OEU08683.1 - 0.059 12.6 1.1 2.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4992 PF16383.5 OEU08683.1 - 0.14 11.7 1.4 0.28 10.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function RXT2_N PF08595.11 OEU08683.1 - 0.67 10.0 6.0 4.3 7.3 0.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal MAM33 PF02330.16 OEU08683.1 - 0.71 9.8 8.3 1.7 8.5 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial glycoprotein Orai-1 PF07856.12 OEU08683.1 - 2.5 7.7 8.3 4.6 6.9 2.2 3.0 3 1 0 3 3 3 0 Mediator of CRAC channel activity DUF1240 PF06836.12 OEU08683.1 - 8.6 7.0 13.3 0.83 10.2 0.4 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) SMN PF06003.12 OEU08683.1 - 9.2 5.4 11.8 0.35 10.1 2.2 2.4 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) DUF711 PF05167.12 OEU08684.1 - 3.7e-83 279.7 0.6 6.9e-44 150.4 0.1 2.0 2 0 0 2 2 2 2 Uncharacterised ACR (DUF711) Inhibitor_I53 PF11714.8 OEU08684.1 - 1 9.6 3.6 6.7 7.0 0.8 2.5 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Pam16 PF03656.13 OEU08686.1 - 0.0084 16.1 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Pam16 DUF3641 PF12345.8 OEU08686.1 - 0.037 14.1 0.4 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) CRAL_TRIO_N PF03765.15 OEU08687.1 - 0.0032 17.6 0.1 0.0084 16.3 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RXLR PF16810.5 OEU08687.1 - 0.008 16.6 1.6 0.17 12.3 0.2 2.6 2 0 0 2 2 2 1 RXLR phytopathogen effector protein, Avirulence activity DUF4196 PF13846.6 OEU08687.1 - 0.04 14.1 1.5 1.8 8.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4196) Gag_p17 PF00540.18 OEU08687.1 - 0.67 9.9 3.1 12 5.9 0.1 2.7 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) NAD_binding_10 PF13460.6 OEU08688.1 - 3.4e-08 33.6 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 2 NAD(P)H-binding SR-25 PF10500.9 OEU08688.1 - 0.0043 16.7 11.5 0.0064 16.1 11.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ABC_trans_N PF14510.6 OEU08688.1 - 0.067 13.8 0.1 5.4 7.7 0.0 2.2 2 0 0 2 2 2 0 ABC-transporter N-terminal DUF508 PF04370.12 OEU08688.1 - 0.16 11.7 8.2 0.26 11.0 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Herpes_pp85 PF04637.12 OEU08688.1 - 0.21 9.9 4.9 0.26 9.7 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RNF111_N PF15303.6 OEU08688.1 - 2.6 7.7 13.3 3.5 7.3 13.3 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Ank_2 PF12796.7 OEU08689.1 - 4.8e-23 81.5 1.5 4.9e-15 55.9 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU08689.1 - 4e-19 66.7 0.2 2e-05 24.6 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OEU08689.1 - 1.2e-16 60.8 5.9 0.0001 22.8 0.2 4.6 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU08689.1 - 1.5e-15 57.0 3.7 5.2e-05 23.4 0.1 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OEU08689.1 - 4.1e-15 55.5 0.9 0.00034 20.9 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat DnaJ PF00226.31 OEU08689.1 - 8.7e-06 25.8 0.4 5.2e-05 23.3 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain OST-HTH PF12872.7 OEU08689.1 - 0.098 12.5 1.7 0.46 10.3 1.2 2.3 2 1 0 2 2 2 0 OST-HTH/LOTUS domain Pkinase PF00069.25 OEU08690.1 - 6.9e-11 42.0 0.0 8.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08690.1 - 1.1e-07 31.5 0.1 1.3e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TLC PF03219.14 OEU08691.1 - 1.7e-13 50.2 2.0 1.3e-11 43.9 1.8 2.2 1 1 0 1 1 1 1 TLC ATP/ADP transporter lci PF12197.8 OEU08691.1 - 0.16 11.8 1.2 0.55 10.1 0.2 2.3 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein DUF1635 PF07795.11 OEU08692.1 - 2.3 8.0 8.2 2 8.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF4611 PF15387.6 OEU08692.1 - 3.3 8.0 16.6 10 6.4 2.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) WD40 PF00400.32 OEU08693.1 - 0.026 15.4 0.1 0.15 13.0 0.1 2.4 1 0 0 1 1 1 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU08693.1 - 0.12 12.6 0.1 5.8 7.3 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MRJP PF03022.16 OEU08693.1 - 0.43 9.9 3.7 0.46 9.8 0.1 2.2 2 0 0 2 2 2 0 Major royal jelly protein DUF2237 PF09996.9 OEU08694.1 - 1.7e-48 163.4 0.2 1.9e-48 163.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) CENP-B_dimeris PF09026.10 OEU08695.1 - 0.23 11.9 5.2 6.8 7.1 0.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain IR1-M PF12185.8 OEU08695.1 - 0.26 11.3 1.5 4.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain GST_C_3 PF14497.6 OEU08698.1 - 1e-07 32.1 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU08698.1 - 5.2e-07 29.9 0.0 8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU08698.1 - 5.7e-05 23.3 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OEU08698.1 - 0.00018 21.9 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU08698.1 - 0.00018 21.5 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-MYND PF01753.18 OEU08700.1 - 9.4e-08 32.0 19.1 2.4e-07 30.7 19.1 1.7 1 0 0 1 1 1 1 MYND finger SR-25 PF10500.9 OEU08701.1 - 7.5 6.1 21.1 7.4 6.1 5.9 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein CSG2 PF16965.5 OEU08701.1 - 9.6 5.0 7.9 1.1 8.2 1.7 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator V_ATPase_I PF01496.19 OEU08704.1 - 0.48 8.3 8.4 0.56 8.1 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 OEU08704.1 - 0.84 9.6 8.5 1.1 9.3 8.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XRN_M PF17846.1 OEU08704.1 - 2 7.3 9.2 2.3 7.1 9.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain GspL_C PF12693.7 OEU08704.1 - 5.8 6.7 13.3 0.84 9.5 0.3 2.1 1 1 1 2 2 2 0 GspL periplasmic domain Asp_protease_2 PF13650.6 OEU08705.1 - 1.6e-13 51.1 1.8 2.6e-06 28.0 0.2 3.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 OEU08705.1 - 2.4e-08 34.4 1.3 0.001 19.6 0.0 3.8 2 2 1 3 3 3 2 gag-polyprotein putative aspartyl protease SAP PF02037.27 OEU08705.1 - 0.0022 17.7 0.3 0.0047 16.6 0.3 1.5 1 0 0 1 1 1 1 SAP domain RVP_2 PF08284.11 OEU08705.1 - 0.089 12.6 0.0 13 5.6 0.0 3.1 3 0 0 3 3 3 0 Retroviral aspartyl protease RVP PF00077.20 OEU08705.1 - 0.16 12.3 0.6 1.8 8.9 0.0 2.8 3 0 0 3 3 3 0 Retroviral aspartyl protease Pap_E4 PF02711.14 OEU08705.1 - 7.7 7.5 10.7 19 6.3 7.1 2.5 2 0 0 2 2 2 0 E4 protein SRP14 PF02290.15 OEU08706.1 - 0.033 14.6 0.2 0.11 12.9 0.2 1.9 1 0 0 1 1 1 0 Signal recognition particle 14kD protein HA PF03457.14 OEU08708.1 - 7.5e-36 122.3 1.9 3e-18 65.9 0.5 2.7 3 0 0 3 3 3 2 Helicase associated domain DUF2722 PF10846.8 OEU08708.1 - 0.0089 15.0 4.9 0.007 15.4 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 OEU08708.1 - 0.027 14.5 10.0 0.025 14.6 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spuma_A9PTase PF03539.14 OEU08708.1 - 0.53 10.4 0.0 0.53 10.4 0.0 2.6 1 1 2 3 3 3 0 Spumavirus aspartic protease (A9) Spt20 PF12090.8 OEU08708.1 - 0.75 9.4 16.6 0.89 9.1 16.6 1.3 1 0 0 1 1 1 0 Spt20 family DUF810 PF05664.11 OEU08709.1 - 0.017 13.7 1.7 0.018 13.6 1.4 1.2 1 1 0 1 1 1 0 Plant family of unknown function (DUF810) REC114-like PF15165.6 OEU08709.1 - 0.089 12.6 2.0 0.1 12.4 2.0 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Folliculin PF11704.8 OEU08709.1 - 0.5 10.2 5.1 0.19 11.6 2.6 1.5 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Glyco_hydro38C2 PF17677.1 OEU08710.1 - 0.13 12.3 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain COPIIcoated_ERV PF07970.12 OEU08711.1 - 5.7e-22 78.6 0.0 1.6e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OEU08711.1 - 1.9e-19 69.8 2.9 7.9e-19 67.8 0.2 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 OEU08711.1 - 2.4e-18 66.0 0.3 1.7e-10 40.8 0.4 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OEU08711.1 - 0.00032 21.1 0.1 0.00072 20.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU08711.1 - 0.00039 20.3 0.2 0.00083 19.3 0.2 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OEU08711.1 - 0.00066 20.0 0.2 0.0031 17.8 0.2 2.3 1 0 0 1 1 1 1 Thioredoxin-like ALS2CR11 PF15729.5 OEU08711.1 - 0.015 14.5 0.6 0.023 13.9 0.6 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Thioredoxin_7 PF13899.6 OEU08711.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Hydrolase_4 PF12146.8 OEU08712.1 - 2.9e-08 33.3 0.1 5.7e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU08712.1 - 4.3e-07 30.8 0.0 7.4e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU08712.1 - 4.4e-05 23.3 0.2 0.00026 20.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU08712.1 - 0.003 17.1 0.4 2.3 7.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 OEU08712.1 - 0.033 13.8 0.1 0.071 12.8 0.1 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 OEU08712.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Toxin_35 PF10530.9 OEU08713.1 - 0.00024 21.0 3.4 0.00024 21.0 3.4 3.5 5 0 0 5 5 5 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Glycoprotein PF03409.15 OEU08713.1 - 0.26 10.1 3.0 0.39 9.5 3.0 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein RR_TM4-6 PF06459.12 OEU08714.1 - 3.5 7.4 8.4 3.3 7.5 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 OEU08714.1 - 9.4 6.0 13.9 13 5.5 13.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein NOG1 PF06858.14 OEU08716.1 - 1.2e-20 73.0 0.0 2.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OEU08716.1 - 6.6e-16 58.4 0.2 6.9e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOG1_N PF17835.1 OEU08716.1 - 1.9e-11 44.2 0.4 4.3e-11 43.0 0.4 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain FeoB_N PF02421.18 OEU08716.1 - 2.1e-05 24.1 0.0 6.5e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OEU08716.1 - 0.0012 19.3 0.0 0.0046 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 OEU08716.1 - 0.0016 18.2 2.2 0.29 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OEU08716.1 - 0.019 14.9 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 OEU08716.1 - 0.025 14.5 0.6 0.99 9.3 0.0 3.2 4 0 0 4 4 4 0 RsgA GTPase Peptidase_M2 PF01401.18 OEU08716.1 - 0.4 9.3 2.7 0.55 8.8 2.7 1.3 1 0 0 1 1 1 0 Angiotensin-converting enzyme Dicty_REP PF05086.12 OEU08716.1 - 0.48 8.3 10.1 0.73 7.7 10.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ArsP_2 PF11449.8 OEU08717.1 - 0.0075 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative, 10TM heavy-metal exporter adh_short PF00106.25 OEU08718.1 - 2.2e-18 66.4 0.1 2.5e-07 30.4 0.1 3.4 2 1 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 OEU08718.1 - 9.5e-06 25.6 0.2 4.8e-05 23.3 0.2 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OEU08718.1 - 8.4e-05 22.2 0.0 8.4e-05 22.2 0.0 2.4 4 0 0 4 4 4 1 Enoyl-(Acyl carrier protein) reductase ATP-grasp_4 PF13535.6 OEU08719.1 - 1e-06 28.4 0.0 4.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OEU08719.1 - 2.9e-06 27.2 0.0 4.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 OEU08719.1 - 0.0033 17.1 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 OEU08719.1 - 0.0064 16.1 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OEU08719.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PBP1_TM PF14812.6 OEU08721.1 - 0.69 10.3 15.3 0.13 12.7 4.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AT_hook PF02178.19 OEU08721.1 - 1.8 8.7 7.6 5.7 7.2 7.6 1.9 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.25 OEU08722.1 - 1.2e-59 201.9 0.0 1.5e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08722.1 - 1.5e-35 122.7 0.0 2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU08722.1 - 2.3e-06 27.1 0.0 1.2e-05 24.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OEU08722.1 - 0.0035 17.3 0.0 0.006 16.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OEU08722.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OEU08722.1 - 0.087 11.7 0.0 0.76 8.7 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain FYVE PF01363.21 OEU08723.1 - 0.079 13.1 12.9 0.15 12.2 12.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-CHY PF05495.12 OEU08723.1 - 0.092 13.2 12.1 0.12 12.8 12.1 1.2 1 0 0 1 1 1 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 OEU08723.1 - 0.52 10.8 12.8 0.85 10.1 12.8 1.4 1 1 0 1 1 1 0 Cytochrome c3 zf-B_box PF00643.24 OEU08723.1 - 2.7 8.2 15.4 18 5.6 3.2 3.2 3 0 0 3 3 3 0 B-box zinc finger DER1 PF04511.15 OEU08724.1 - 1.9e-56 191.0 13.2 2.4e-56 190.7 13.2 1.0 1 0 0 1 1 1 1 Der1-like family DOT1 PF08123.13 OEU08725.1 - 0.0038 16.8 0.0 0.041 13.4 0.0 2.4 1 1 1 2 2 2 1 Histone methylation protein DOT1 LRR_9 PF14580.6 OEU08726.1 - 0.72 9.3 10.9 1.6 8.2 0.3 3.0 3 0 0 3 3 3 0 Leucine-rich repeat Hydrolase_4 PF12146.8 OEU08727.1 - 1.3e-13 50.8 0.0 1.1e-09 37.9 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU08727.1 - 3.3e-07 30.2 0.0 0.00057 19.6 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU08727.1 - 1.2e-06 29.3 0.0 7.4e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OEU08727.1 - 1.2e-06 28.3 0.0 0.00045 19.9 0.1 2.0 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OEU08727.1 - 6.6e-06 25.7 0.0 0.041 13.4 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 OEU08727.1 - 1.5e-05 24.8 0.0 2.4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OEU08727.1 - 0.00019 21.0 0.1 0.014 14.9 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OEU08727.1 - 0.042 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 OEU08727.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Asp2 PF16929.5 OEU08727.1 - 0.09 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter LIDHydrolase PF10230.9 OEU08727.1 - 0.15 11.6 0.0 3.7 7.0 0.0 2.0 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 OEU08727.1 - 0.17 11.7 0.0 5.6 6.7 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family PhoPQ_related PF10142.9 OEU08727.1 - 0.28 9.8 0.0 0.37 9.4 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein SNF2_N PF00176.23 OEU08728.1 - 2.4e-45 154.8 0.0 4.2e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_UBOX PF13445.6 OEU08728.1 - 6.1e-07 29.4 3.1 1.4e-06 28.2 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU08728.1 - 1.4e-06 28.5 5.9 3.7e-06 27.2 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU08728.1 - 1.5e-06 27.9 5.1 3.3e-06 26.9 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU08728.1 - 2.7e-06 27.1 1.7 7e-06 25.8 1.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU08728.1 - 4.4e-06 26.6 4.9 1e-05 25.4 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU08728.1 - 0.00025 20.8 5.1 0.00025 20.8 5.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU08728.1 - 0.00047 20.3 3.6 0.0018 18.4 3.6 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 OEU08728.1 - 0.00091 19.3 0.0 0.0039 17.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU08728.1 - 0.0086 16.4 0.0 0.026 14.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_topoisoIV PF00521.20 OEU08728.1 - 0.023 13.6 0.1 0.097 11.5 0.0 2.0 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A Prok-RING_4 PF14447.6 OEU08728.1 - 0.045 13.6 5.9 0.31 10.9 6.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OEU08728.1 - 0.054 13.3 4.5 0.13 12.0 4.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OEU08728.1 - 0.17 12.0 2.3 0.45 10.6 2.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tnp_zf-ribbon_2 PF13842.6 OEU08728.1 - 0.37 11.6 4.4 2.3 9.1 4.4 2.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Zn_ribbon_17 PF17120.5 OEU08728.1 - 0.52 10.0 3.5 1.4 8.6 3.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_9 PF14369.6 OEU08728.1 - 0.82 10.0 3.3 2.4 8.5 1.0 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-3CxxC_2 PF17180.4 OEU08728.1 - 0.95 10.3 6.0 0.25 12.1 1.6 2.4 2 0 0 2 2 1 0 Zinc-binding domain FYVE PF01363.21 OEU08728.1 - 1.8 8.8 6.5 0.89 9.7 3.5 2.1 2 0 0 2 2 1 0 FYVE zinc finger FAD_binding_6 PF00970.24 OEU08729.1 - 4e-12 46.3 0.0 2e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OEU08729.1 - 0.041 14.0 0.0 11 6.1 0.0 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 OEU08729.1 - 0.087 13.5 0.0 5.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4281 PF14108.6 OEU08732.1 - 2.8e-20 73.0 2.3 3.3e-20 72.7 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) UL73_N PF12522.8 OEU08732.1 - 0.84 9.4 3.5 1.6 8.6 3.5 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal STELLO PF03385.17 OEU08734.1 - 3.8e-19 68.8 0.0 5e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases SARAF PF06682.12 OEU08736.1 - 1.9e-06 27.8 1.6 1.9e-06 27.8 1.6 1.8 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CLN3 PF02487.17 OEU08736.1 - 0.0011 18.1 1.2 0.002 17.3 1.2 1.4 1 0 0 1 1 1 1 CLN3 protein Shisa PF13908.6 OEU08736.1 - 0.002 18.4 1.5 0.002 18.4 1.5 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator 7tm_1 PF00001.21 OEU08736.1 - 0.0031 16.9 0.0 0.0031 16.9 0.0 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) SCIMP PF15050.6 OEU08736.1 - 0.015 15.8 0.4 0.037 14.5 0.4 1.6 1 0 0 1 1 1 0 SCIMP protein DUF2681 PF10883.8 OEU08736.1 - 0.045 14.2 2.0 0.045 14.2 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) API5 PF05918.11 OEU08736.1 - 0.068 12.0 3.4 0.093 11.5 3.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Presenilin PF01080.17 OEU08736.1 - 0.075 11.8 7.6 0.17 10.6 7.6 1.6 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 OEU08736.1 - 0.17 10.3 9.0 0.27 9.7 9.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med26_M PF15694.5 OEU08736.1 - 0.27 11.2 17.2 0.049 13.7 10.5 2.0 2 0 0 2 2 2 0 Mediator complex subunit 26 middle domain SF1-HH PF16275.5 OEU08736.1 - 0.6 10.5 9.8 1.4 9.3 9.8 1.6 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF1180 PF06679.12 OEU08736.1 - 1.6 9.1 8.0 60 4.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF4834 PF16118.5 OEU08736.1 - 9 7.3 20.9 0.47 11.4 3.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) RSN1_7TM PF02714.15 OEU08737.1 - 5.4e-23 81.7 19.0 8.7e-23 81.0 19.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OEU08737.1 - 6.4e-06 26.0 6.8 4.2e-05 23.4 0.2 3.6 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport SWIRM-assoc_1 PF16495.5 OEU08737.1 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 SWIRM-associated region 1 DUF3439 PF11921.8 OEU08737.1 - 4.5 7.3 13.7 0.052 13.5 3.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 OEU08738.1 - 5.3e-67 226.0 0.0 5.9e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08738.1 - 8.3e-31 107.2 0.0 9.4e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU08738.1 - 5.9e-06 25.3 0.0 8.7e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OEU08738.1 - 8.2e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OEU08738.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU08738.1 - 0.035 14.0 0.1 1.3 8.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OEU08739.1 - 7.8e-68 228.7 0.0 9.7e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08739.1 - 7.2e-25 87.7 0.0 9.5e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU08739.1 - 0.00043 19.2 0.0 0.00063 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU08739.1 - 0.0025 17.2 0.1 0.0037 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU08739.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 OEU08739.1 - 0.19 10.6 0.6 0.76 8.7 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase HEAT_2 PF13646.6 OEU08739.1 - 0.2 12.1 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 HEAT repeats Hist_deacetyl PF00850.19 OEU08740.1 - 1.9e-31 109.7 0.0 1.4e-16 60.8 0.0 2.5 2 0 0 2 2 2 2 Histone deacetylase domain HSP90 PF00183.18 OEU08741.1 - 5.5e-47 160.8 7.3 2.9e-38 132.1 1.5 2.3 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 OEU08741.1 - 5.1e-14 52.3 0.2 1.5e-13 50.7 0.2 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OEU08741.1 - 2e-10 41.1 0.1 5.6e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Flg_bbr_C PF06429.13 OEU08743.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal SUIM_assoc PF16619.5 OEU08744.1 - 0.0044 17.0 2.5 0.0044 17.0 2.5 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF3452 PF11934.8 OEU08744.1 - 3.8 7.1 10.9 26 4.4 10.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF1871 PF08958.10 OEU08745.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) Pkinase_Tyr PF07714.17 OEU08746.1 - 2.3e-27 95.9 0.0 2.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU08746.1 - 3.4e-27 95.5 0.0 4.9e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OEU08746.1 - 0.00037 19.9 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU08746.1 - 0.0067 16.4 0.1 0.0091 15.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU08748.1 - 1.8e-36 125.8 0.0 2.4e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08748.1 - 1.2e-31 110.0 0.0 1.3e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU08748.1 - 0.00069 19.0 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU08748.1 - 0.00074 19.5 0.0 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family cobW PF02492.19 OEU08749.1 - 5.1e-45 153.2 1.6 5.1e-45 153.2 1.6 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU08749.1 - 1.1e-14 54.1 0.0 2.7e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OEU08749.1 - 1.6e-05 24.9 0.8 0.028 14.3 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OEU08749.1 - 0.0015 18.1 0.2 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 OEU08749.1 - 0.0095 16.5 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OEU08749.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dcc1 PF09724.9 OEU08749.1 - 0.026 13.9 0.0 0.32 10.3 0.0 2.1 1 1 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 MMR_HSR1 PF01926.23 OEU08749.1 - 0.043 13.9 0.4 0.76 9.9 0.3 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OEU08749.1 - 0.05 13.9 0.1 0.16 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OEU08749.1 - 0.068 13.6 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OEU08749.1 - 0.083 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 OEU08749.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OEU08749.1 - 0.11 13.0 0.1 0.28 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 OEU08749.1 - 0.13 12.4 0.2 0.6 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 OEU08749.1 - 0.34 10.3 2.3 1.1 8.6 0.3 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family PT PF04886.12 OEU08751.1 - 4.5e-31 106.1 86.4 4.8e-06 26.0 9.4 6.1 1 1 3 4 4 4 3 PT repeat PT PF04886.12 OEU08752.1 - 4.4e-05 22.9 86.2 9.5e+03 -3.7 0.2 6.1 2 1 1 3 3 3 0 PT repeat Rhamno_transf PF11316.8 OEU08753.1 - 1.3e-08 34.6 2.8 1.1e-07 31.5 1.2 2.6 2 1 0 2 2 2 2 Putative rhamnosyl transferase DUF1899 PF08953.11 OEU08755.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) GalKase_gal_bdg PF10509.9 OEU08756.1 - 2.2e-20 71.9 0.1 4.3e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 OEU08756.1 - 4.8e-11 42.9 0.0 5e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OEU08756.1 - 0.048 13.9 0.1 0.048 13.9 0.1 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain Pkinase PF00069.25 OEU08758.1 - 8.2e-06 25.4 0.0 8.2e-06 25.4 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain TFIIA PF03153.13 OEU08758.1 - 0.014 15.4 15.2 0.017 15.1 15.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 OEU08758.1 - 0.74 8.4 10.5 0.88 8.2 10.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EIIBC-GUT_N PF03612.14 OEU08758.1 - 0.88 9.3 3.5 5.8 6.6 0.4 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SRP72 PF08492.12 OEU08758.1 - 2.9 8.4 7.5 3.8 8.0 1.4 2.4 2 0 0 2 2 2 0 SRP72 RNA-binding domain PDGF_N PF04692.13 OEU08758.1 - 3.4 8.5 11.3 0.34 11.7 1.6 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Pkinase PF00069.25 OEU08759.1 - 2.2e-26 92.8 2.7 1.1e-25 90.5 2.7 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08759.1 - 5.5e-14 52.1 0.1 8.1e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1221 PF06760.11 OEU08759.1 - 0.01 15.3 0.2 0.015 14.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Peptidase_S8 PF00082.22 OEU08760.1 - 1.1e-30 107.0 5.9 1.1e-30 107.0 5.9 2.6 2 1 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 OEU08760.1 - 2.5e-14 53.0 0.2 7.4e-14 51.5 0.1 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain Cwf_Cwc_15 PF04889.12 OEU08760.1 - 0.37 10.5 6.3 0.71 9.6 6.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ferritin PF00210.24 OEU08761.1 - 1.2e-22 80.4 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain tRNA-synt_1c PF00749.21 OEU08762.1 - 2.6e-95 319.0 0.1 3.2e-95 318.7 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PPDK_N PF01326.19 OEU08763.1 - 6.4e-58 196.6 0.0 1e-57 195.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OEU08763.1 - 3.4e-16 58.7 0.0 8.8e-16 57.4 0.0 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain C_GCAxxG_C_C PF09719.10 OEU08763.1 - 0.039 14.2 0.5 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) PPDK_N PF01326.19 OEU08764.1 - 1.3e-38 133.1 0.0 1.9e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Carb_anhydrase PF00194.21 OEU08765.1 - 7.5e-19 68.3 5.6 1e-14 54.7 0.3 3.3 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase Acyl-CoA_dh_1 PF00441.24 OEU08766.1 - 1.5e-28 99.9 0.0 2.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OEU08766.1 - 3.8e-28 98.4 0.0 7.4e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OEU08766.1 - 1.8e-15 56.9 0.0 3.5e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3719 PF12516.8 OEU08766.1 - 4.7e-06 26.2 4.6 0.35 10.6 0.1 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF3719) Acyl-CoA_dh_2 PF08028.11 OEU08766.1 - 6.6e-06 26.4 0.0 1.3e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Inhibitor_I68 PF10468.9 OEU08766.1 - 0.17 12.3 7.5 7.3 7.1 0.2 3.6 3 0 0 3 3 3 0 Carboxypeptidase inhibitor I68 CTXphi_pIII-N1 PF16710.5 OEU08766.1 - 0.46 10.6 4.3 9.3 6.4 0.1 3.5 1 1 2 3 3 3 0 N-terminal N1 domain of Vibrio phage CTXphi pIII MFS_5 PF05631.14 OEU08767.1 - 2e-37 129.0 9.8 1.7e-18 66.7 0.4 3.6 3 1 0 3 3 3 3 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OEU08767.1 - 2.7e-23 82.5 32.6 1.6e-14 53.6 0.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 OEU08767.1 - 0.042 12.4 19.6 0.082 11.4 9.1 3.3 2 1 1 3 3 3 0 MFS/sugar transport protein Nop14 PF04147.12 OEU08767.1 - 0.058 11.6 9.5 0.13 10.5 9.5 1.5 1 0 0 1 1 1 0 Nop14-like family GWT1 PF06423.12 OEU08767.1 - 0.14 12.3 2.8 1.9 8.6 0.0 3.6 3 1 0 3 3 3 0 GWT1 FAM176 PF14851.6 OEU08767.1 - 0.7 9.5 12.0 3.6 7.3 2.9 2.9 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 OEU08767.1 - 3.1 6.0 10.0 1.4 7.1 0.0 2.2 2 0 0 2 2 2 0 CDC45-like protein TRAP_alpha PF03896.16 OEU08767.1 - 3.4 6.8 6.2 0.96 8.6 0.2 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF3494 PF11999.8 OEU08768.1 - 2.9e-58 197.0 17.5 3.7e-58 196.6 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Pkinase PF00069.25 OEU08769.1 - 5.8e-75 252.1 0.6 7.3e-75 251.7 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08769.1 - 1.8e-34 119.2 0.2 2.7e-34 118.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU08769.1 - 2.3e-09 37.0 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU08769.1 - 6.1e-06 26.3 0.0 0.017 15.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU08769.1 - 2.6e-05 23.2 0.0 0.00022 20.1 0.0 2.0 1 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OEU08769.1 - 0.0025 17.2 0.1 0.0049 16.3 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OEU08769.1 - 0.0078 15.8 0.7 0.017 14.7 0.7 1.6 1 0 0 1 1 1 1 RIO1 family Mito_carr PF00153.27 OEU08770.1 - 3.7e-08 33.2 2.2 0.0001 22.2 0.1 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Popeye PF04831.13 OEU08771.1 - 6.8e-06 26.3 0.0 8.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 OEU08771.1 - 0.0026 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Trypsin PF00089.26 OEU08772.1 - 1.1e-49 169.3 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU08772.1 - 7e-06 27.0 0.1 1.6e-05 25.9 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-LITAF-like PF10601.9 OEU08773.1 - 0.05 13.9 1.3 0.05 13.9 1.3 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Trypsin PF00089.26 OEU08774.1 - 5.5e-28 98.3 0.3 6e-26 91.6 0.3 2.1 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU08774.1 - 0.12 13.3 0.0 0.21 12.5 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Polyketide_cyc2 PF10604.9 OEU08775.1 - 0.00024 21.4 0.0 0.00031 21.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OEU08775.1 - 0.00085 19.5 0.2 0.0011 19.2 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ribonuc_L-PSP PF01042.21 OEU08776.1 - 1.2e-30 106.0 0.2 1.3e-30 105.9 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rab3-GTPase_cat PF13890.6 OEU08776.1 - 0.081 12.6 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Pep_deformylase PF01327.21 OEU08777.1 - 2e-21 76.2 0.4 1.2e-20 73.7 0.4 1.9 1 1 0 1 1 1 1 Polypeptide deformylase DUF4329 PF14220.6 OEU08777.1 - 0.038 14.0 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Polyketide_cyc PF03364.20 OEU08778.1 - 3.3e-07 30.6 0.0 8.8e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OEU08778.1 - 6.8e-05 23.2 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pkinase PF00069.25 OEU08779.1 - 2.3e-22 79.6 0.0 3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08779.1 - 2.1e-10 40.3 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU08779.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 OEU08779.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF2834 PF11196.8 OEU08780.1 - 0.00036 20.8 10.5 0.00037 20.8 4.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2834) ATG16 PF08614.11 OEU08781.1 - 0.0005 20.4 22.9 0.023 14.9 5.1 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OEU08781.1 - 0.0089 14.9 19.0 0.014 14.3 19.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3552 PF12072.8 OEU08781.1 - 0.01 15.2 29.2 0.015 14.7 12.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 OEU08781.1 - 0.016 14.8 10.3 0.02 14.5 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Filament PF00038.21 OEU08781.1 - 0.02 14.5 19.9 0.28 10.7 9.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein Kre28 PF17097.5 OEU08781.1 - 0.035 13.1 12.6 0.044 12.7 12.6 1.1 1 0 0 1 1 1 0 Spindle pole body component DUF725 PF05267.12 OEU08781.1 - 0.039 13.9 1.6 0.039 13.9 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF725) HAP1_N PF04849.13 OEU08781.1 - 0.095 11.9 20.7 0.042 13.1 17.9 1.7 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF3153 PF11353.8 OEU08781.1 - 0.11 12.1 2.6 0.15 11.6 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) BLOC1_2 PF10046.9 OEU08781.1 - 0.12 12.6 13.7 1.6 9.1 5.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FPP PF05911.11 OEU08781.1 - 0.14 10.3 19.4 0.17 10.0 19.4 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF2203 PF09969.9 OEU08781.1 - 0.14 12.8 13.7 0.78 10.5 2.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 OEU08781.1 - 0.24 11.8 21.9 2.9 8.2 10.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HOOK PF05622.12 OEU08781.1 - 0.48 8.5 22.7 1.5 6.9 23.0 1.6 1 1 0 1 1 1 0 HOOK protein DUF4407 PF14362.6 OEU08781.1 - 0.51 9.7 11.5 0.65 9.3 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 OEU08781.1 - 0.61 10.2 12.0 1.3 9.2 12.0 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 OEU08781.1 - 1.1 9.3 27.0 0.46 10.5 16.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HemX PF04375.14 OEU08781.1 - 1.4 8.1 13.6 1.1 8.4 9.1 1.9 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3584 PF12128.8 OEU08781.1 - 1.7 6.1 19.0 2.9 5.3 19.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) IMD PF08397.11 OEU08781.1 - 1.8 7.9 15.8 0.78 9.1 13.4 1.5 1 1 1 2 2 2 0 IRSp53/MIM homology domain Atg14 PF10186.9 OEU08781.1 - 1.8 7.6 16.3 2.2 7.3 16.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 OEU08781.1 - 1.9 9.2 14.6 20 5.9 4.5 3.7 1 1 2 3 3 3 0 SlyX UPF0449 PF15136.6 OEU08781.1 - 2 8.9 16.4 7.9 7.0 2.4 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Laminin_II PF06009.12 OEU08781.1 - 2.5 8.1 13.6 0.86 9.6 6.2 2.1 1 1 1 2 2 2 0 Laminin Domain II Fez1 PF06818.15 OEU08781.1 - 2.8 8.4 23.6 9.6 6.6 23.7 1.8 1 1 0 1 1 1 0 Fez1 DUF4200 PF13863.6 OEU08781.1 - 3.3 8.1 29.4 5.1 7.5 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Allexi_40kDa PF05549.11 OEU08781.1 - 3.3 7.1 10.4 2 7.8 1.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein V_ATPase_I PF01496.19 OEU08781.1 - 3.3 5.5 16.1 0.071 11.0 6.3 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 OEU08781.1 - 3.6 7.9 20.1 4.4 7.7 3.9 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 OEU08781.1 - 3.7 7.6 31.0 0.072 13.1 10.0 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain SpecificRecomb PF10136.9 OEU08781.1 - 4.7 5.4 6.5 5.7 5.1 6.5 1.0 1 0 0 1 1 1 0 Site-specific recombinase KELK PF15796.5 OEU08781.1 - 5 7.6 26.2 4.9 7.7 20.7 2.9 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MctB PF11382.8 OEU08781.1 - 6.7 6.3 7.1 1.4 8.6 2.5 1.8 1 1 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF16 PF01519.16 OEU08781.1 - 10 6.7 16.9 17 6.0 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 PT PF04886.12 OEU08782.1 - 0.69 9.5 11.2 99 2.6 11.2 2.5 1 1 0 1 1 1 0 PT repeat gp45-slide_C PF09116.10 OEU08783.1 - 0.046 13.8 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal DUF563 PF04577.14 OEU08784.1 - 1.7e-18 67.5 0.1 3.2e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5316 PF17247.2 OEU08784.1 - 0.099 12.7 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) TLD PF07534.16 OEU08785.1 - 1.3e-26 93.5 0.1 9.4e-24 84.2 0.1 2.7 1 1 0 1 1 1 1 TLD TFIIA PF03153.13 OEU08785.1 - 7.7 6.4 29.9 11 5.9 29.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_U57 PF05582.12 OEU08785.1 - 9.5 5.4 12.8 0.094 12.0 1.1 2.2 2 0 0 2 2 2 0 YabG peptidase U57 5-FTHF_cyc-lig PF01812.20 OEU08787.1 - 5.6e-15 55.7 0.0 1.3e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 OEU08788.1 - 2e-18 66.0 0.0 3.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OEU08788.1 - 3e-05 23.8 0.0 5.4e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OEU08788.1 - 0.015 14.9 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU08788.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Plasmid_parti PF01672.16 OEU08789.1 - 1.7 9.3 6.7 0.77 10.4 2.8 2.3 1 1 0 2 2 2 0 Putative plasmid partition protein Rhomboid PF01694.22 OEU08790.1 - 2.8e-06 27.4 6.6 2.8e-06 27.4 6.6 2.2 1 1 1 2 2 2 1 Rhomboid family Acyl_transf_3 PF01757.22 OEU08790.1 - 0.0013 17.8 1.0 0.0016 17.6 1.0 1.0 1 0 0 1 1 1 1 Acyltransferase family MtrE PF04206.12 OEU08790.1 - 0.0036 16.7 4.8 0.0051 16.2 4.8 1.3 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit E DUF4191 PF13829.6 OEU08790.1 - 2.7 7.3 10.1 0.18 11.1 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Peptidase_M32 PF02074.15 OEU08791.1 - 4.5e-57 193.9 0.2 4.7e-42 144.4 0.1 2.0 1 1 1 2 2 2 2 Carboxypeptidase Taq (M32) metallopeptidase PIG-L PF02585.17 OEU08792.1 - 7e-20 72.0 0.0 1.4e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase YMF19 PF02326.15 OEU08792.1 - 0.12 13.2 1.4 3.6 8.4 0.2 2.9 3 0 0 3 3 3 0 Plant ATP synthase F0 Thioredoxin_8 PF13905.6 OEU08793.1 - 2.2e-24 85.6 0.1 2.8e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OEU08793.1 - 5.8e-09 35.9 0.2 9.5e-07 28.8 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 OEU08793.1 - 1.7e-08 34.3 0.0 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU08793.1 - 1.4e-07 31.4 0.0 2e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OEU08793.1 - 9.9e-06 26.0 0.0 1.4e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OEU08793.1 - 0.0013 18.9 0.1 0.0048 17.1 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 OEU08793.1 - 0.0094 15.6 0.2 0.046 13.3 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 OEU08793.1 - 0.024 14.8 0.3 4.5 7.6 0.1 2.2 1 1 1 2 2 2 0 Glutaredoxin TraF PF13728.6 OEU08793.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OEU08793.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Mlh1_C PF16413.5 OEU08795.1 - 2.3e-56 191.1 0.8 1e-53 182.5 0.0 3.5 3 1 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OEU08795.1 - 7.5e-18 64.3 0.7 1.7e-17 63.2 0.7 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OEU08795.1 - 6.4e-11 42.2 0.0 2.1e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OEU08795.1 - 3.5e-06 27.5 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CPSF73-100_C PF11718.8 OEU08795.1 - 0.025 14.1 0.5 0.06 12.9 0.5 1.6 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term GRIN_C PF15235.6 OEU08795.1 - 0.33 11.2 7.2 0.11 12.7 0.6 2.5 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus ThiD2 PF17792.1 OEU08795.1 - 0.93 10.0 8.5 0.46 11.0 0.8 3.3 3 0 0 3 3 3 0 ThiD2 family K_channel_TID PF07941.11 OEU08795.1 - 7 7.2 6.8 0.33 11.4 0.6 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DisA-linker PF10635.9 OEU08796.1 - 0.018 14.8 0.3 0.029 14.1 0.3 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region SMN PF06003.12 OEU08796.1 - 0.13 11.5 3.5 0.16 11.2 0.1 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Peptidase_S10 PF00450.22 OEU08797.1 - 1.7e-87 294.5 1.1 2.9e-53 181.8 0.0 2.2 1 1 1 2 2 2 2 Serine carboxypeptidase DnaJ PF00226.31 OEU08798.1 - 1e-15 57.6 0.4 1.1e-15 57.5 0.4 1.0 1 0 0 1 1 1 1 DnaJ domain Aldedh PF00171.22 OEU08799.1 - 5.8e-133 443.8 0.4 6.7e-133 443.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Troponin PF00992.20 OEU08799.1 - 0.012 15.9 0.9 0.022 15.1 0.9 1.3 1 0 0 1 1 1 0 Troponin TSC22 PF01166.18 OEU08799.1 - 0.087 13.1 0.3 0.28 11.5 0.3 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family LZ3wCH PF18517.1 OEU08799.1 - 0.11 12.6 0.7 9.3 6.4 0.0 2.6 1 1 1 2 2 2 0 Leucine zipper with capping helix domain DnaJ PF00226.31 OEU08800.1 - 6.6e-24 83.8 2.4 1.7e-23 82.5 2.4 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 OEU08800.1 - 3.4e-10 39.3 2.1 0.00054 19.7 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08800.1 - 1.5e-09 37.2 11.6 0.043 13.9 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OEU08800.1 - 0.00011 22.6 0.0 0.057 13.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU08800.1 - 0.069 13.8 1.7 24 5.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU08800.1 - 0.24 12.1 1.8 13 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU08800.1 - 0.42 10.9 17.1 0.39 11.1 0.9 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PBP1_TM PF14812.6 OEU08800.1 - 0.54 10.7 0.0 0.54 10.7 0.0 4.3 2 2 3 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ADH_zinc_N PF00107.26 OEU08801.1 - 1.2e-16 60.9 0.0 2.5e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU08801.1 - 1.9e-06 27.7 0.0 7e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OEU08801.1 - 0.052 14.6 0.0 0.1 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OEU08801.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase SNO PF01174.19 OEU08802.1 - 8.6e-37 126.8 0.0 1.8e-28 99.7 0.0 2.5 2 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OEU08802.1 - 0.00082 19.0 0.5 0.002 17.8 0.2 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain AAA PF00004.29 OEU08803.1 - 0.0037 17.7 1.9 0.0081 16.6 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PPI_Ypi1 PF07491.11 OEU08804.1 - 7.5e-21 73.7 0.3 7.5e-21 73.7 0.3 2.2 2 0 0 2 2 2 1 Protein phosphatase inhibitor PBP1_TM PF14812.6 OEU08804.1 - 0.18 12.2 4.0 0.16 12.3 2.3 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KCT2 PF17818.1 OEU08804.1 - 0.68 10.0 5.9 1 9.4 5.9 1.4 1 1 0 1 1 1 0 Keratinocyte-associated gene product bZIP_1 PF00170.21 OEU08805.1 - 0.0024 17.9 4.5 0.0024 17.9 4.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor Trypsin_2 PF13365.6 OEU08806.1 - 3e-30 106.1 1.8 4.4e-30 105.6 1.8 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OEU08806.1 - 6.9e-13 48.9 0.1 1.2e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 OEU08806.1 - 3.1e-05 24.2 0.0 8.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 OEU08806.1 - 0.0041 15.9 0.1 0.74 8.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 PDZ PF00595.24 OEU08806.1 - 0.024 15.0 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Tudor_2 PF18104.1 OEU08806.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain HTH_Crp_2 PF13545.6 OEU08807.1 - 0.019 14.9 0.1 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3933 PF13069.6 OEU08807.1 - 0.029 14.2 0.1 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Peroxin-22 PF12827.7 OEU08807.1 - 0.7 9.8 4.6 0.36 10.8 0.1 2.7 3 1 1 4 4 4 0 Peroxisomal biogenesis protein family CENP-B_dimeris PF09026.10 OEU08807.1 - 7.3 7.0 11.0 3.2 8.2 6.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UCH PF00443.29 OEU08808.1 - 1e-40 139.9 2.9 1e-40 139.9 2.9 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU08808.1 - 1.3e-16 61.2 7.6 1.3e-16 61.2 7.6 4.0 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OEU08810.1 - 1.8e-08 34.2 13.4 3.5e-08 33.3 13.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tankyrase_bdg_C PF15327.6 OEU08810.1 - 0.081 13.4 0.2 0.081 13.4 0.2 2.7 2 1 0 2 2 2 0 Tankyrase binding protein C terminal domain UCH_1 PF13423.6 OEU08810.1 - 4.8 6.7 21.5 1.2e+03 -1.2 21.5 2.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OEU08811.1 - 1.2e-10 41.3 3.1 1.4e-10 41.2 3.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.11 OEU08811.1 - 0.55 10.3 11.1 3.1 7.8 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Presenilin PF01080.17 OEU08811.1 - 1.9 7.2 3.2 2 7.1 3.2 1.2 1 0 0 1 1 1 0 Presenilin Pap_E4 PF02711.14 OEU08811.1 - 4.3 8.4 15.4 1.5 9.9 1.5 2.5 2 1 0 2 2 2 0 E4 protein DUF3391 PF11871.8 OEU08811.1 - 8.8 6.9 8.0 7.7 7.1 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Cupin_7 PF12973.7 OEU08812.1 - 2.2e-16 59.6 0.1 4.1e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 OEU08812.1 - 0.00019 21.1 1.4 0.00043 19.9 1.4 1.6 1 0 0 1 1 1 1 Cupin domain Thioredoxin PF00085.20 OEU08813.1 - 2.5e-15 56.3 0.4 3.4e-11 43.1 0.1 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 OEU08813.1 - 0.0024 18.3 1.0 0.015 15.8 0.1 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OEU08813.1 - 0.016 15.4 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 OEU08813.1 - 0.029 14.7 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 OEU08813.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Holin_BhlA PF10960.8 OEU08813.1 - 0.23 11.4 1.8 0.37 10.8 1.8 1.3 1 0 0 1 1 1 0 BhlA holin family Thioredoxin PF00085.20 OEU08814.1 - 1.4e-06 28.2 0.0 5.7e-06 26.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Phage_Mu_Gam PF07352.12 OEU08814.1 - 0.01 15.8 2.8 0.59 10.0 2.6 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein FHA PF00498.26 OEU08816.1 - 0.0023 18.3 0.0 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OEU08816.1 - 0.018 15.3 0.1 0.072 13.4 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Methyltransf_3 PF01596.17 OEU08817.1 - 3.7e-07 29.6 1.6 2.3e-05 23.7 1.6 2.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OEU08817.1 - 5e-07 30.7 0.1 9e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF5058 PF16481.5 OEU08817.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Glyco_hydro_81 PF03639.13 OEU08818.1 - 1.5e-14 53.9 0.1 3e-13 49.6 0.1 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Sigma_reg_N PF13800.6 OEU08818.1 - 0.15 12.3 1.2 0.3 11.4 1.2 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Hydin_ADK PF17213.3 OEU08819.1 - 0.031 14.6 2.8 0.033 14.5 2.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CCDC50_N PF15295.6 OEU08819.1 - 0.038 14.1 11.3 0.054 13.7 11.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Presenilin PF01080.17 OEU08819.1 - 0.09 11.5 1.1 0.1 11.3 1.1 1.2 1 0 0 1 1 1 0 Presenilin UPF0172 PF03665.13 OEU08819.1 - 0.21 11.6 7.3 0.44 10.6 7.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) TMIE PF16038.5 OEU08819.1 - 0.22 11.4 5.5 0.12 12.2 2.3 2.2 2 1 1 3 3 3 0 TMIE protein RNR_Alpha PF17975.1 OEU08819.1 - 0.44 11.1 2.3 0.76 10.3 2.3 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain Cse1 PF08506.10 OEU08820.1 - 1.6e-08 33.8 0.0 4.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Cse1 Importin_rep_4 PF18808.1 OEU08820.1 - 0.00043 20.5 5.5 0.24 11.7 0.1 3.6 3 0 0 3 3 3 2 Importin repeat RTP1_C1 PF10363.9 OEU08820.1 - 0.014 15.5 0.2 2.4 8.4 0.1 3.1 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 FlxA PF14282.6 OEU08821.1 - 0.057 13.4 14.6 0.035 14.1 1.6 3.3 2 1 1 3 3 3 0 FlxA-like protein CENP-H PF05837.12 OEU08821.1 - 0.078 13.4 0.6 0.078 13.4 0.6 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Rod_cone_degen PF15201.6 OEU08821.1 - 0.084 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration Bcr-Abl_Oligo PF09036.10 OEU08821.1 - 0.79 9.8 2.8 5.8 7.0 0.2 2.6 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain TSC22 PF01166.18 OEU08821.1 - 0.86 10.0 11.5 2.6 8.4 0.7 3.7 3 1 1 4 4 4 0 TSC-22/dip/bun family Syntaxin PF00804.25 OEU08821.1 - 1 9.0 13.0 1 9.0 0.9 2.8 1 1 2 3 3 3 0 Syntaxin TBX PF12598.8 OEU08821.1 - 1.5 9.6 6.3 9.1 7.2 1.4 2.7 1 1 1 2 2 2 0 T-box transcription factor YabA PF06156.13 OEU08821.1 - 2.2 8.9 22.5 37 5.0 4.8 3.4 1 1 0 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 OEU08821.1 - 9.1 6.8 16.1 1 9.9 0.4 4.0 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins PI_PP_I PF18363.1 OEU08821.1 - 9.8 6.4 7.5 1.3 9.2 1.1 2.7 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain ETAA1 PF15350.6 OEU08823.1 - 0.043 12.1 0.4 0.063 11.6 0.4 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue SET PF00856.28 OEU08824.1 - 4.1e-09 37.1 0.1 1.8e-06 28.4 0.1 3.2 2 1 0 2 2 2 2 SET domain SAF PF08666.12 OEU08824.1 - 0.023 15.3 0.1 2.6 8.8 0.0 2.8 2 0 0 2 2 2 0 SAF domain HHH_4 PF14490.6 OEU08824.1 - 0.17 11.9 0.1 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain WD40 PF00400.32 OEU08827.1 - 2.5e-07 31.3 17.1 0.56 11.2 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Rad60-SLD PF11976.8 OEU08828.1 - 4e-23 81.0 1.2 4.1e-14 52.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OEU08828.1 - 7.6e-11 41.6 0.5 3e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin family RBD PF02196.15 OEU08828.1 - 0.028 14.5 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Raf-like Ras-binding domain Peptidase_M8 PF01457.16 OEU08829.1 - 2.7e-59 201.2 0.0 3.2e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin HLH PF00010.26 OEU08830.1 - 0.00081 19.3 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 OEU08830.1 - 0.0024 18.1 0.1 0.0083 16.4 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OEU08830.1 - 0.0024 17.8 0.1 0.0084 16.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 OEU08830.1 - 0.003 17.8 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OEU08830.1 - 0.087 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain CCDC74_C PF14917.6 OEU08830.1 - 9.8 6.7 17.5 0.05 14.1 3.2 3.1 3 0 0 3 3 3 0 Coiled coil protein 74, C terminal Thioredoxin PF00085.20 OEU08831.1 - 8.2e-19 67.5 0.0 1.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU08831.1 - 4.3e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OEU08831.1 - 0.00015 21.6 0.0 0.00049 19.9 0.0 1.8 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU08831.1 - 0.00029 21.3 0.0 0.0031 17.9 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OEU08831.1 - 0.0042 17.1 0.3 0.014 15.5 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.21 OEU08831.1 - 0.0054 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU08831.1 - 0.006 16.3 0.2 0.012 15.3 0.1 1.7 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OEU08831.1 - 0.014 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 OEU08831.1 - 0.016 15.4 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 OEU08831.1 - 0.053 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Shisa PF13908.6 OEU08831.1 - 0.45 10.7 3.1 0.79 9.9 3.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Macoilin PF09726.9 OEU08831.1 - 4.3 5.8 10.8 5.6 5.4 10.8 1.3 1 1 0 1 1 1 0 Macoilin family Peptidase_M8 PF01457.16 OEU08832.1 - 5.2e-39 134.3 3.1 1.7e-36 126.1 0.0 2.5 1 1 2 3 3 3 2 Leishmanolysin SET PF00856.28 OEU08833.1 - 2.1e-09 38.0 0.5 3.1e-05 24.4 0.0 3.9 2 2 0 2 2 2 2 SET domain Flagellin_IN PF07196.13 OEU08833.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif WD40 PF00400.32 OEU08834.1 - 1.1e-25 89.4 15.6 6.8e-09 36.2 0.2 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 OEU08834.1 - 1.7e-06 27.0 1.6 0.023 13.3 0.2 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OEU08834.1 - 3e-05 24.2 0.1 0.13 12.6 0.0 3.4 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OEU08834.1 - 0.043 13.1 0.0 0.23 10.8 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain BBS2_Mid PF14783.6 OEU08834.1 - 0.13 12.3 0.1 20 5.3 0.0 2.8 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region EamA PF00892.20 OEU08836.1 - 1.3e-11 44.8 26.0 2.2e-08 34.4 4.4 4.7 5 1 0 5 5 5 3 EamA-like transporter family HCO3_cotransp PF00955.21 OEU08836.1 - 0.0077 15.1 0.3 0.021 13.7 0.2 1.8 2 0 0 2 2 2 1 HCO3- transporter family DUF1459 PF07312.11 OEU08836.1 - 0.029 14.6 0.4 0.31 11.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) ETRAMP PF09716.10 OEU08836.1 - 0.079 13.0 0.0 1.5 9.0 0.0 3.2 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) PBP1_TM PF14812.6 OEU08836.1 - 9.3 6.7 6.5 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2251 PF10008.9 OEU08837.1 - 0.16 12.1 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) EF-hand_5 PF13202.6 OEU08838.1 - 4e-24 83.0 4.7 3e-06 26.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 OEU08838.1 - 3.9e-23 79.2 8.8 5.6e-06 25.5 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OEU08838.1 - 1.9e-19 67.9 8.3 0.00018 21.2 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OEU08838.1 - 2.8e-18 66.1 15.1 2.4e-08 34.3 2.1 3.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 OEU08838.1 - 4.6e-12 45.6 12.0 0.0011 18.8 0.4 4.4 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU08838.1 - 3.2e-06 27.4 0.8 0.031 14.6 0.0 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OEU08838.1 - 0.087 13.2 0.2 7.5 7.0 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain DUF1180 PF06679.12 OEU08839.1 - 0.049 14.1 3.0 0.089 13.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AOX PF01786.17 OEU08840.1 - 1.5e-71 240.4 0.3 1.9e-71 240.1 0.3 1.0 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 OEU08840.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Pkinase PF00069.25 OEU08841.1 - 9.9e-45 153.0 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08841.1 - 1.9e-21 76.5 0.0 3.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU08841.1 - 1.7e-07 30.9 0.0 3.3e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OEU08841.1 - 0.004 16.8 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 OEU08841.1 - 0.0053 16.4 0.1 0.01 15.5 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OEU08841.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SecD-TM1 PF13721.6 OEU08841.1 - 0.037 14.5 0.0 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Kdo PF06293.14 OEU08841.1 - 0.039 13.3 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OEU08841.1 - 0.065 12.3 0.1 0.099 11.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-MYND PF01753.18 OEU08843.1 - 1.8e-10 40.7 12.2 2.8e-10 40.1 12.2 1.3 1 0 0 1 1 1 1 MYND finger DUF2511 PF10709.9 OEU08843.1 - 0.022 15.0 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) HEPN_RES_NTD1 PF18870.1 OEU08843.1 - 0.33 11.1 0.1 0.33 11.1 0.1 2.4 2 1 0 2 2 2 0 HEPN/RES N-terminal domain 1 Cytochrome_C7 PF14522.6 OEU08843.1 - 9.5 6.3 12.2 0.24 11.4 4.4 2.4 2 2 0 2 2 2 0 Cytochrome c7 and related cytochrome c Peptidase_S9 PF00326.21 OEU08845.1 - 2.1e-19 69.8 0.1 4.3e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_21 PF05050.12 OEU08847.1 - 1.3e-08 35.0 0.0 3.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain mRNA_cap_C PF03919.15 OEU08848.1 - 1.6e-06 28.7 0.0 2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain GRIP PF01465.20 OEU08848.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 GRIP domain Mpv17_PMP22 PF04117.12 OEU08850.1 - 1.3e-22 79.8 1.0 1.3e-22 79.8 1.0 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family Chloroa_b-bind PF00504.21 OEU08850.1 - 0.004 17.7 0.1 0.017 15.6 0.0 1.8 1 1 1 2 2 2 2 Chlorophyll A-B binding protein SATase_N PF06426.14 OEU08851.1 - 1.6e-14 54.1 0.1 4e-14 52.9 0.1 1.7 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 OEU08851.1 - 1.1e-06 28.1 7.5 0.0014 18.2 2.1 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Acyltransferase PF01553.21 OEU08852.1 - 7e-16 58.1 0.0 8.9e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase CRAL_TRIO PF00650.20 OEU08853.1 - 3.1e-11 43.2 0.0 4.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain TPR_12 PF13424.6 OEU08854.1 - 7.6e-24 83.8 22.8 2.6e-09 37.2 0.5 8.2 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU08854.1 - 7e-23 79.5 8.6 1.6e-06 27.7 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU08854.1 - 5.4e-20 69.8 16.3 0.00027 20.8 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU08854.1 - 1.6e-14 52.8 9.3 0.0013 18.8 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU08854.1 - 1.7e-11 43.3 14.2 0.0042 17.0 0.0 7.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU08854.1 - 1.5e-09 37.4 25.2 0.0023 17.7 0.0 8.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 OEU08854.1 - 1.5e-06 28.4 3.0 5 8.0 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU08854.1 - 3.7e-06 27.5 4.4 6.7 7.5 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU08854.1 - 4.2e-06 26.4 8.1 1.1e-05 25.0 2.8 3.6 3 2 0 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 OEU08854.1 - 0.00062 20.0 7.8 10 6.8 0.0 6.6 7 1 0 7 7 6 1 Tetratricopeptide repeat DUF4618 PF15397.6 OEU08854.1 - 0.0057 16.1 1.3 0.012 15.0 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) TPR_14 PF13428.6 OEU08854.1 - 0.0092 16.7 7.0 13 7.0 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OEU08854.1 - 0.047 13.7 1.6 0.99 9.5 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 NOA36 PF06524.12 OEU08854.1 - 0.68 9.2 15.2 1.8 7.8 2.5 2.8 2 0 0 2 2 2 0 NOA36 protein AAA PF00004.29 OEU08855.1 - 4.4e-39 133.9 0.0 7.8e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OEU08855.1 - 1.4e-17 63.4 0.1 3.1e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OEU08855.1 - 5.7e-09 35.6 0.1 1.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OEU08855.1 - 1.1e-06 28.8 0.0 3.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OEU08855.1 - 1.6e-06 28.1 0.2 8e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU08855.1 - 1.4e-05 25.6 0.1 3.7e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU08855.1 - 3.7e-05 24.0 0.1 0.00095 19.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU08855.1 - 7e-05 22.6 0.3 0.0005 19.9 0.2 2.3 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OEU08855.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OEU08855.1 - 0.0031 17.3 0.3 0.092 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OEU08855.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OEU08855.1 - 0.02 14.6 0.1 0.11 12.1 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 OEU08855.1 - 0.026 14.4 0.1 0.091 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OEU08855.1 - 0.029 13.7 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OEU08855.1 - 0.05 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OEU08855.1 - 0.059 12.6 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain CPT PF07931.12 OEU08855.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 OEU08855.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 OEU08855.1 - 0.082 12.2 0.2 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 OEU08855.1 - 0.12 12.9 0.2 0.6 10.7 0.0 2.3 3 1 0 3 3 2 0 AAA domain AAA_7 PF12775.7 OEU08855.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OEU08855.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OEU08855.1 - 0.17 11.6 0.2 0.49 10.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OEU08856.1 - 4.2e-48 162.2 0.1 2e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 OEU08856.1 - 1.1e-31 108.9 0.0 2.4e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 OEU08856.1 - 9.8e-19 67.4 0.0 8.2e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 OEU08856.1 - 3.9e-14 52.7 0.6 1.8e-06 27.6 0.0 4.6 3 1 0 3 3 3 3 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OEU08856.1 - 9.5e-13 48.6 0.1 0.003 17.6 0.0 4.3 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 OEU08856.1 - 2.6e-12 46.5 0.0 5.8e-06 25.8 0.0 3.1 3 0 0 3 3 3 2 AIG1 family RsgA_GTPase PF03193.16 OEU08856.1 - 2e-07 31.1 0.2 0.11 12.4 0.0 3.8 2 1 0 4 4 4 2 RsgA GTPase ABC_tran PF00005.27 OEU08856.1 - 1.4e-06 28.9 0.0 0.061 13.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Roc PF08477.13 OEU08856.1 - 3.2e-06 27.4 0.0 0.031 14.5 0.0 3.3 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OEU08856.1 - 0.00032 21.1 0.0 0.32 11.4 0.0 3.1 1 1 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 OEU08856.1 - 0.0014 17.8 0.0 0.14 11.2 0.0 2.6 3 0 0 3 3 3 1 MCM P-loop domain TniB PF05621.11 OEU08856.1 - 0.0071 15.8 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 1 Bacterial TniB protein cobW PF02492.19 OEU08856.1 - 0.0083 15.7 2.5 0.15 11.7 0.1 3.3 2 2 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 OEU08856.1 - 0.011 15.1 0.0 0.83 9.0 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.22 OEU08856.1 - 0.012 15.2 0.1 5.7 6.5 0.0 3.6 2 2 0 2 2 2 0 Ras family AAA_18 PF13238.6 OEU08856.1 - 0.024 15.2 0.0 18 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 OEU08856.1 - 0.029 14.1 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 OEU08856.1 - 0.038 13.3 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 OEU08856.1 - 0.044 14.2 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 OEU08856.1 - 0.046 13.4 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OEU08856.1 - 0.085 12.6 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU08856.1 - 0.14 12.4 0.0 9.2 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain Nitroreductase PF00881.24 OEU08857.1 - 3.2e-14 53.3 0.0 4.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OEU08857.1 - 0.0018 17.9 0.0 1.2 8.6 0.0 2.3 2 1 0 2 2 2 2 Putative TM nitroreductase Thioredoxin PF00085.20 OEU08858.1 - 3.3e-12 46.3 0.0 5.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin BAF PF02961.14 OEU08860.1 - 0.0079 16.6 0.1 1.2 9.6 0.0 3.3 3 1 1 4 4 4 1 Barrier to autointegration factor DUF4754 PF15946.5 OEU08860.1 - 0.033 14.5 0.2 0.059 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) RWD PF05773.22 OEU08861.1 - 0.003 17.8 3.2 0.9 9.8 0.3 2.8 3 1 0 3 3 3 2 RWD domain Ig_5 PF16681.5 OEU08863.1 - 0.025 15.0 0.1 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Trypan_PARP PF05887.11 OEU08864.1 - 0.12 12.3 4.0 0.22 11.5 4.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 OEU08864.1 - 4 5.8 5.4 5.9 5.3 5.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Diphthami_syn_2 PF01902.17 OEU08865.1 - 4.2e-24 85.3 0.0 2.5e-22 79.5 0.0 2.1 1 1 0 1 1 1 1 Diphthamide synthase Glyco_hydro_99 PF16317.5 OEU08866.1 - 1.2e-18 67.3 0.6 8.2e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 OEU08866.1 - 2.7e-07 30.4 0.1 6.4e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase WbsX Macoilin PF09726.9 OEU08866.1 - 0.13 10.8 0.2 0.14 10.6 0.2 1.1 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 OEU08866.1 - 0.16 10.1 10.1 0.21 9.7 10.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Redoxin PF08534.10 OEU08867.1 - 0.0034 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU08867.1 - 0.026 14.5 0.0 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Adaptin_binding PF10199.9 OEU08867.1 - 0.18 12.4 9.7 0.42 11.2 7.1 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 IF-2B PF01008.17 OEU08869.1 - 1.3e-65 221.4 0.1 2.5e-65 220.5 0.1 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family bPH_1 PF08000.11 OEU08870.1 - 2.6e-36 124.4 0.0 9.2e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial PH domain bPH_1 PF08000.11 OEU08871.1 - 1.3e-21 76.9 0.0 1.4e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 OEU08871.1 - 0.03 14.7 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain DUF4114 PF13448.6 OEU08872.1 - 3.2 8.6 13.1 8.9 7.2 13.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4114) DUF2971 PF11185.8 OEU08872.1 - 6.4 8.0 10.6 23 6.3 10.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) His_Phos_1 PF00300.22 OEU08873.1 - 4.2e-16 59.2 0.0 1.4e-09 37.9 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-CCHC_5 PF14787.6 OEU08874.1 - 0.00099 18.8 1.0 0.0035 17.0 1.0 1.9 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OEU08874.1 - 0.084 13.0 1.2 0.24 11.6 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Gly_transf_sug PF04488.15 OEU08875.1 - 1.5e-06 28.7 0.4 4.3e-06 27.3 0.4 1.9 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif potato_inhibit PF00280.18 OEU08875.1 - 2.6e-06 28.0 0.0 5.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Potato inhibitor I family SRP_SPB PF02978.19 OEU08875.1 - 0.0049 17.5 0.4 0.01 16.4 0.4 1.5 1 0 0 1 1 1 1 Signal peptide binding domain TcdA_TcdB PF12919.7 OEU08875.1 - 0.0059 15.9 0.0 0.0059 15.9 0.0 2.6 4 0 0 4 4 4 1 TcdA/TcdB catalytic glycosyltransferase domain adh_short_C2 PF13561.6 OEU08876.1 - 1.7e-05 24.5 1.0 3.1e-05 23.6 0.1 1.8 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU08876.1 - 0.00054 19.5 0.2 0.012 15.1 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase AJAP1_PANP_C PF15298.6 OEU08876.1 - 0.005 17.1 1.9 0.0074 16.5 1.9 1.4 1 0 0 1 1 1 1 AJAP1/PANP C-terminus SSP160 PF06933.11 OEU08876.1 - 0.96 7.6 11.4 1.4 7.0 11.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peripla_BP_2 PF01497.18 OEU08877.1 - 1e-07 31.8 0.0 1.6e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein Med14 PF08638.11 OEU08877.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 GATase_3 PF07685.14 OEU08878.1 - 3.9e-29 101.6 0.0 7e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 OEU08878.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 OEU08878.1 - 6.4e-14 52.2 1.2 2.5e-12 47.0 1.2 2.2 1 1 0 1 1 1 1 AAA domain FTHFS PF01268.19 OEU08878.1 - 0.016 13.4 0.4 0.024 12.8 0.4 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase ParA PF10609.9 OEU08878.1 - 0.021 14.3 0.3 0.039 13.4 0.3 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DJ-1_PfpI PF01965.24 OEU08878.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family DUF1611 PF07755.11 OEU08878.1 - 0.13 11.5 1.3 0.5 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain CBP_BcsQ PF06564.12 OEU08878.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ SNO PF01174.19 OEU08878.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DnaJ_C PF01556.18 OEU08879.1 - 1.5e-38 132.2 0.4 2.2e-38 131.7 0.4 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OEU08879.1 - 1.1e-21 76.7 2.5 1.9e-21 75.9 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OEU08879.1 - 6.8e-07 29.6 5.6 1.6e-06 28.4 5.6 1.5 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.10 OEU08879.1 - 0.015 15.0 2.1 0.25 11.1 0.1 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain RPN7 PF10602.9 OEU08880.1 - 8.8e-10 38.6 0.4 1.5e-08 34.6 0.4 2.9 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OEU08880.1 - 0.078 13.5 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 PCI domain Mucin PF01456.17 OEU08880.1 - 0.11 12.5 7.5 0.027 14.5 3.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 OEU08880.1 - 2.8 7.9 10.6 0.31 11.0 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SET PF00856.28 OEU08881.1 - 2.7e-13 50.6 0.0 2.8e-07 31.1 0.0 3.3 2 1 0 2 2 2 2 SET domain Laminin_II PF06009.12 OEU08881.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II Peptidase_M50B PF13398.6 OEU08882.1 - 2.9e-36 125.0 15.2 3.7e-36 124.6 15.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like SprT-like PF10263.9 OEU08882.1 - 0.054 13.3 0.2 0.09 12.6 0.2 1.3 1 0 0 1 1 1 0 SprT-like family Astro_capsid_p PF12226.8 OEU08883.1 - 9 5.3 16.1 18 4.3 16.1 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-CCCH_2 PF14608.6 OEU08884.1 - 0.057 13.9 0.7 0.057 13.9 0.7 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PAM2 PF07145.15 OEU08884.1 - 0.14 11.9 0.7 0.29 10.9 0.7 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DUF3619 PF12279.8 OEU08886.1 - 0.092 13.1 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Med15 PF09606.10 OEU08888.1 - 0.0066 15.2 19.2 0.0093 14.7 17.5 1.8 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Nexin_C PF08628.12 OEU08888.1 - 0.011 16.3 1.0 0.14 12.7 0.4 2.6 3 0 0 3 3 3 0 Sorting nexin C terminal SUIM_assoc PF16619.5 OEU08888.1 - 0.016 15.3 16.8 0.28 11.3 8.4 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF572 PF04502.13 OEU08888.1 - 0.025 14.2 5.8 0.078 12.6 5.8 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) Afi1 PF07792.12 OEU08888.1 - 2.8 8.4 14.5 0.98 9.9 1.2 3.0 3 1 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CAML PF14963.6 OEU08888.1 - 3.8 7.5 6.9 3.7 7.6 0.4 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand IATP PF04568.12 OEU08889.1 - 0.11 13.0 1.1 0.16 12.4 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Conotoxin PF02950.17 OEU08890.1 - 5.7 8.0 4.9 8.2 7.5 0.2 3.0 3 1 1 4 4 4 0 Conotoxin DUF2722 PF10846.8 OEU08892.1 - 0.0017 17.4 0.2 0.0026 16.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Asp_protease_2 PF13650.6 OEU08892.1 - 0.0024 18.5 0.1 1.2 9.8 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Gag_p12 PF01141.18 OEU08892.1 - 0.13 12.7 1.0 1.2 9.6 0.0 2.4 1 1 1 2 2 2 0 Gag polyprotein, inner coat protein p12 gag-asp_proteas PF13975.6 OEU08892.1 - 0.13 12.8 0.3 33 5.1 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease PDZ PF00595.24 OEU08893.1 - 9.9e-07 29.0 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU08893.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU08893.1 - 0.0066 16.7 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain CdiI_3 PF18616.1 OEU08893.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 CDI immunity proteins COBRA PF04833.15 OEU08894.1 - 0.027 14.4 0.2 4.3 7.2 0.1 2.2 1 1 1 2 2 2 0 COBRA-like protein CBM9_2 PF16011.5 OEU08896.1 - 6.9e-07 29.2 0.4 8.9e-07 28.8 0.4 1.1 1 0 0 1 1 1 1 Carbohydrate-binding family 9 Methyltransf_32 PF13679.6 OEU08897.1 - 2.4e-13 50.4 0.1 1.7e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU08897.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF5527 PF17665.1 OEU08897.1 - 0.068 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Menin PF05053.13 OEU08897.1 - 2.5 6.4 8.4 3.6 5.9 8.4 1.1 1 0 0 1 1 1 0 Menin CAF1C_H4-bd PF12265.8 OEU08898.1 - 4.9e-14 52.3 0.2 5.8e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OEU08898.1 - 6.9e-11 42.5 3.8 0.069 14.0 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU08898.1 - 3e-06 27.4 0.1 0.04 14.2 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain UQ_con PF00179.26 OEU08899.1 - 5.8e-19 68.1 0.0 6.8e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OEU08899.1 - 0.057 13.7 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OEU08899.1 - 0.16 11.8 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 UEV domain zf-MYND PF01753.18 OEU08900.1 - 2.1e-09 37.3 13.3 5.1e-09 36.1 13.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OEU08900.1 - 0.93 9.9 13.0 2.2 8.6 13.0 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding VKG_Carbox PF05090.14 OEU08901.1 - 6.7e-23 81.2 13.1 1.8e-22 79.8 13.1 1.8 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase DUF2818 PF10993.8 OEU08901.1 - 0.11 13.0 1.4 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) adh_short PF00106.25 OEU08902.1 - 2.7e-30 105.3 0.3 1.5e-23 83.3 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU08902.1 - 7e-18 65.0 0.0 7e-18 65.0 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU08902.1 - 2.2e-09 37.5 1.8 1.1e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.15 OEU08902.1 - 0.0009 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OEU08902.1 - 0.22 11.0 0.8 6.8 6.1 0.0 2.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family CTP_transf_1 PF01148.20 OEU08903.1 - 2.5e-38 132.4 6.8 1.3e-31 110.4 2.3 2.2 2 1 0 2 2 2 2 Cytidylyltransferase family CarS-like PF01864.17 OEU08903.1 - 0.0085 16.1 7.2 0.022 14.8 0.3 2.7 2 1 1 3 3 3 2 CDP-archaeol synthase COX15-CtaA PF02628.15 OEU08903.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF3671 PF12420.8 OEU08903.1 - 1.8 8.7 9.0 2.3 8.3 3.2 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF4271 PF14093.6 OEU08903.1 - 9.9 6.0 15.4 2.9 7.7 6.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4271) SDA1 PF05285.12 OEU08904.1 - 0.0048 16.4 29.5 0.014 14.8 21.2 2.4 2 0 0 2 2 2 2 SDA1 Presenilin PF01080.17 OEU08904.1 - 4.2 6.0 22.6 2.4 6.8 12.9 2.7 2 0 0 2 2 2 0 Presenilin DUF2756 PF10956.8 OEU08905.1 - 0.007 16.9 1.8 0.016 15.7 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2756) RibD_C PF01872.17 OEU08905.1 - 0.025 14.4 1.3 3.3 7.5 0.5 2.2 2 0 0 2 2 2 0 RibD C-terminal domain WW PF00397.26 OEU08906.1 - 0.00065 19.7 1.8 0.0026 17.8 1.8 2.0 1 1 0 1 1 1 1 WW domain Sulfate_transp PF00916.20 OEU08906.1 - 0.18 10.5 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Sulfate permease family zf-CDGSH PF09360.10 OEU08909.1 - 4.7e-09 36.3 0.3 7.4e-09 35.7 0.0 1.5 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Med15 PF09606.10 OEU08910.1 - 0.0023 16.7 1.5 0.0032 16.3 1.5 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Cas_Cmr3 PF09700.10 OEU08910.1 - 0.027 13.9 0.3 0.045 13.2 0.3 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) YajC PF02699.15 OEU08910.1 - 0.21 11.5 0.9 0.54 10.2 0.9 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit HD_4 PF13328.6 OEU08910.1 - 0.3 10.8 2.6 1.9 8.2 1.0 2.2 2 0 0 2 2 2 0 HD domain ATE_C PF04377.15 OEU08911.1 - 1.5e-38 132.5 7.3 2.5e-37 128.5 7.3 2.5 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OEU08911.1 - 0.0013 19.0 0.7 0.006 16.9 0.7 2.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Ribosomal_L28 PF00830.19 OEU08912.1 - 0.029 14.5 5.8 0.12 12.6 0.9 2.5 1 1 1 2 2 2 0 Ribosomal L28 family Mqo PF06039.15 OEU08912.1 - 0.047 12.2 1.3 0.06 11.9 0.8 1.4 1 1 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) GET2 PF08690.10 OEU08912.1 - 0.42 10.2 4.6 0.5 10.0 4.6 1.2 1 1 0 1 1 1 0 GET complex subunit GET2 LRR_6 PF13516.6 OEU08913.1 - 0.003 17.5 5.8 5.6 7.3 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich repeat Tn7_Tnp_TnsA_C PF08721.11 OEU08913.1 - 0.13 12.9 1.5 0.49 11.1 0.3 2.7 2 0 0 2 2 2 0 TnsA endonuclease C terminal PdxA PF04166.12 OEU08913.1 - 3.1 7.1 5.5 2.1 7.6 0.8 2.2 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA C4bp_oligo PF18453.1 OEU08913.1 - 7 6.9 12.7 9.3 6.5 3.0 2.6 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha Evr1_Alr PF04777.13 OEU08914.1 - 1.4e-13 51.2 1.1 4.8e-13 49.4 0.3 2.4 3 0 0 3 3 3 1 Erv1 / Alr family Thioredoxin PF00085.20 OEU08914.1 - 1.9e-13 50.3 0.2 3.9e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU08914.1 - 0.00081 19.7 0.2 0.0032 17.7 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU08914.1 - 0.00087 19.7 0.2 0.0018 18.7 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OEU08914.1 - 0.083 12.2 0.1 0.083 12.2 0.1 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family SAP PF02037.27 OEU08915.1 - 1.6e-07 30.9 0.4 1.6e-07 30.9 0.4 1.9 2 0 0 2 2 2 1 SAP domain SRAP PF02586.14 OEU08916.1 - 3e-37 128.3 0.2 3.5e-37 128.1 0.2 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Peroxidase_2 PF01328.17 OEU08917.1 - 7.9e-13 49.3 0.0 1.4e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 ZT_dimer PF16916.5 OEU08919.1 - 1.3e-08 34.8 0.1 1.9e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SpoU_methylase PF00588.19 OEU08920.1 - 8.9e-27 94.0 0.0 1.4e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family TCR PF03638.15 OEU08922.1 - 1.1e-25 89.6 49.4 7.8e-13 48.5 19.9 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain NAD_binding_10 PF13460.6 OEU08925.1 - 3.1e-36 125.0 0.1 4.3e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU08925.1 - 4.7e-08 32.9 0.1 9.4e-08 31.9 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OEU08925.1 - 4.9e-06 26.2 0.0 8.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU08925.1 - 0.00015 20.8 0.2 0.00021 20.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OEU08925.1 - 0.0011 18.2 0.5 0.75 8.9 0.0 3.1 3 0 0 3 3 3 1 Male sterility protein DapB_N PF01113.20 OEU08925.1 - 0.0075 16.4 1.9 0.019 15.1 1.1 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus E2F_TDP PF02319.20 OEU08926.1 - 8.8e-32 109.0 0.0 5e-18 64.9 0.2 2.7 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OEU08926.1 - 0.0089 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIA PF03153.13 OEU08929.1 - 0.012 15.6 19.3 0.017 15.2 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 OEU08929.1 - 2.3 8.1 10.6 3.5 7.5 10.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 OEU08929.1 - 3.1 6.4 10.8 4.6 5.8 10.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAAX_1 PF15895.5 OEU08930.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 CAAX box cerebral protein 1 Gram_pos_anchor PF00746.21 OEU08930.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Peptidase_M7 PF02031.16 OEU08932.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family MIF4G PF02854.19 OEU08933.1 - 3.6e-29 101.9 6.3 5.3e-29 101.4 6.3 1.1 1 0 0 1 1 1 1 MIF4G domain VasI PF11319.8 OEU08933.1 - 0.0039 16.9 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Type VI secretion system VasI, EvfG, VC_A0118 MA3 PF02847.17 OEU08934.1 - 1.8e-10 40.8 0.1 2e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 MA3 domain V-SNARE_C PF12352.8 OEU08935.1 - 0.01 16.1 0.4 0.042 14.1 0.4 2.1 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus zf-TAZ PF02135.16 OEU08937.1 - 1.4e-07 31.8 18.4 1.4e-07 31.8 18.4 1.9 2 0 0 2 2 2 1 TAZ zinc finger Polyketide_cyc PF03364.20 OEU08938.1 - 0.013 15.7 0.0 0.046 13.9 0.0 2.1 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OEU08938.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Proteasome PF00227.26 OEU08940.1 - 1.2e-37 129.2 0.0 1.4e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cadherin_4 PF17803.1 OEU08942.1 - 6.8e-06 26.6 0.1 3.4e-05 24.4 0.1 2.3 1 0 0 1 1 1 1 Bacterial cadherin-like domain Big_9 PF17963.1 OEU08942.1 - 4.6e-05 24.1 4.5 0.00013 22.7 1.8 3.2 2 1 0 2 2 2 1 Bacterial Ig domain Laminin_G_3 PF13385.6 OEU08942.1 - 0.0026 17.9 0.6 1.3 9.1 0.1 2.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Cadherin_3 PF16184.5 OEU08942.1 - 0.0059 16.6 0.4 0.024 14.6 0.0 2.3 2 0 0 2 2 2 1 Cadherin-like DUF5421 PF17458.2 OEU08942.1 - 0.027 13.9 0.7 0.052 12.9 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) 2OG-FeII_Oxy_3 PF13640.6 OEU08943.1 - 3e-08 34.5 0.0 5.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU08943.1 - 0.0061 17.0 0.0 0.012 16.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 OEU08944.1 - 1.3e-46 158.5 0.0 1.3e-22 80.8 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OEU08944.1 - 4.5e-12 45.9 0.1 0.0018 17.7 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU08944.1 - 1.2e-10 41.7 0.2 0.0037 17.1 0.0 4.4 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system 4HB PF17947.1 OEU08944.1 - 2.4e-07 30.7 0.6 4.9e-05 23.3 0.0 2.7 2 0 0 2 2 2 1 Four helical bundle domain MMR_HSR1 PF01926.23 OEU08944.1 - 2.6e-05 24.2 0.8 0.21 11.7 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OEU08944.1 - 7e-05 23.1 0.0 0.094 13.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain CLP1_P PF16575.5 OEU08944.1 - 0.00044 20.1 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 OEU08944.1 - 0.00047 19.8 0.1 0.098 12.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 OEU08944.1 - 0.00055 20.2 0.1 0.5 10.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 OEU08944.1 - 0.002 18.3 0.1 1.3 9.3 0.0 4.0 3 2 1 4 4 3 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OEU08944.1 - 0.0028 18.1 0.0 2.3 8.6 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OEU08944.1 - 0.0043 17.6 6.2 0.29 11.6 0.3 3.4 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OEU08944.1 - 0.0057 16.6 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 OEU08944.1 - 0.015 15.5 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 OEU08944.1 - 0.017 14.9 5.1 0.82 9.3 0.1 3.0 3 0 0 3 3 2 0 AAA ATPase domain RNA_helicase PF00910.22 OEU08944.1 - 0.019 15.4 0.0 9.6 6.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OEU08944.1 - 0.021 14.8 0.0 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain HEAT_EZ PF13513.6 OEU08944.1 - 0.026 15.0 2.9 6.9 7.3 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat ATPase_2 PF01637.18 OEU08944.1 - 0.031 14.2 0.1 2.1 8.2 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 OEU08944.1 - 0.038 13.7 0.0 2.3 7.9 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OEU08944.1 - 0.064 13.6 0.3 1.8 8.9 0.0 3.0 4 0 0 4 4 3 0 AAA ATPase domain DUF87 PF01935.17 OEU08944.1 - 0.069 13.2 0.0 2 8.5 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain Thy1 PF02511.15 OEU08944.1 - 0.087 12.6 0.2 0.92 9.3 0.1 2.3 2 0 0 2 2 2 0 Thymidylate synthase complementing protein ATP-synt_ab PF00006.25 OEU08944.1 - 0.096 12.3 0.1 0.48 10.1 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4250 PF14056.6 OEU08944.1 - 0.11 12.4 3.7 2.7 8.0 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4250) AAA_14 PF13173.6 OEU08944.1 - 0.13 12.3 0.0 2.7 8.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF2129 PF09902.9 OEU08944.1 - 0.14 12.3 0.1 15 5.8 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) PRA1 PF03208.19 OEU08945.1 - 1.5e-10 40.9 1.1 2e-10 40.5 1.1 1.2 1 0 0 1 1 1 1 PRA1 family protein CPBP PF02517.16 OEU08945.1 - 0.089 13.2 4.6 0.16 12.4 4.6 1.4 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease Phytoreo_S7 PF07236.11 OEU08945.1 - 0.19 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Pkinase PF00069.25 OEU08946.1 - 6.9e-61 205.9 0.0 7.9e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU08946.1 - 4.4e-38 131.1 0.0 5.4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU08946.1 - 0.024 14.6 0.0 2.2 8.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family VAPB_antitox PF02697.14 OEU08946.1 - 0.1 13.4 0.3 15 6.5 0.0 2.5 2 0 0 2 2 2 0 Putative antitoxin Peptidase_M18 PF02127.15 OEU08947.1 - 1.4e-146 488.7 0.0 1.6e-146 488.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OEU08947.1 - 0.00087 18.4 0.1 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase DUF1487 PF07368.11 OEU08947.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) LRR_8 PF13855.6 OEU08948.1 - 4.7e-06 26.3 0.2 0.012 15.4 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU08948.1 - 0.058 13.8 0.0 12 6.5 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU08948.1 - 0.39 11.5 1.8 30 5.7 0.0 4.4 6 1 0 6 6 6 0 Leucine Rich Repeat Steroid_dh PF02544.16 OEU08949.1 - 1.1e-08 35.2 11.0 3.9e-05 23.7 0.3 3.5 2 1 1 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF4834 PF16118.5 OEU08949.1 - 0.0022 18.9 6.1 1 10.4 0.1 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) DUF3963 PF13124.6 OEU08949.1 - 0.048 13.6 0.4 0.21 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) DUF2149 PF09919.9 OEU08949.1 - 0.14 12.4 0.0 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) ORC_WH_C PF18137.1 OEU08949.1 - 4.2 7.4 8.4 0.61 10.1 1.1 2.4 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal NAC PF01849.18 OEU08950.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 NAC domain DEAD PF00270.29 OEU08951.1 - 1.2e-31 109.9 0.5 1.2e-20 74.0 0.1 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU08951.1 - 2.6e-27 95.4 0.1 1e-25 90.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU08951.1 - 8.5e-07 29.1 0.0 4.7e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OEU08951.1 - 0.0088 14.9 0.1 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 OEU08951.1 - 0.034 14.4 0.8 6.9 6.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF4694 PF15765.5 OEU08951.1 - 0.043 13.9 2.8 0.092 12.8 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) OHCU_decarbox PF09349.10 OEU08953.1 - 3.1e-32 112.2 0.0 4.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Transthyretin PF00576.21 OEU08953.1 - 2.7e-30 105.3 0.0 5.3e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF2209 PF09974.9 OEU08953.1 - 0.19 12.1 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) DEAD PF00270.29 OEU08954.1 - 4.5e-43 147.0 0.0 9.9e-43 145.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU08954.1 - 2.4e-30 105.1 0.0 1.4e-29 102.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU08954.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OEU08954.1 - 0.00084 19.7 0.0 0.032 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OEU08954.1 - 0.0009 19.0 0.1 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 OEU08954.1 - 0.0031 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OEU08954.1 - 0.034 13.5 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 OEU08954.1 - 0.15 12.4 0.1 0.66 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain LAM_C PF12544.8 OEU08955.1 - 0.2 11.8 0.1 0.2 11.8 0.1 3.4 3 1 0 3 3 3 0 Lysine-2,3-aminomutase UQ_con PF00179.26 OEU08956.1 - 2.8e-19 69.1 0.0 3.3e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OEU08956.1 - 7.2e-05 22.6 0.0 9.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 OEU08956.1 - 0.095 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 OEU08956.1 - 0.22 11.2 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UAA PF08449.11 OEU08958.1 - 3.7e-58 197.1 21.1 4.5e-58 196.8 21.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU08958.1 - 2.4e-06 27.8 24.8 0.00013 22.1 11.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU08958.1 - 2.5e-05 23.8 15.0 3.4e-05 23.4 15.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 OEU08958.1 - 0.00013 21.1 4.7 0.00013 21.1 4.7 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Leu_zip PF15294.6 OEU08959.1 - 0.0011 18.5 6.9 0.0013 18.3 6.9 1.2 1 0 0 1 1 1 1 Leucine zipper CCDC92 PF14916.6 OEU08959.1 - 0.0031 17.2 0.4 0.009 15.8 0.3 1.9 1 1 0 1 1 1 1 Coiled-coil domain of unknown function Golgin_A5 PF09787.9 OEU08959.1 - 0.0046 16.5 9.4 0.0056 16.2 9.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 OEU08959.1 - 0.048 13.7 0.3 0.048 13.7 0.3 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Bestrophin PF01062.21 OEU08960.1 - 1.3e-11 44.5 0.4 4.5e-11 42.7 0.4 1.7 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pro_isomerase PF00160.21 OEU08961.1 - 0.00022 21.5 0.2 0.00066 20.0 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_7 PF13899.6 OEU08962.1 - 0.096 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Cytochrome_C7 PF14522.6 OEU08962.1 - 4.6 7.3 11.9 2.4 8.2 8.5 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c BLM_N PF16202.5 OEU08963.1 - 0.13 11.4 11.6 0.18 10.9 11.6 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein AMP-binding PF00501.28 OEU08963.1 - 0.75 8.3 3.3 0.84 8.2 3.3 1.0 1 0 0 1 1 1 0 AMP-binding enzyme BNIP3 PF06553.12 OEU08963.1 - 2.8 7.6 8.0 3.2 7.4 8.0 1.0 1 0 0 1 1 1 0 BNIP3 SET PF00856.28 OEU08964.1 - 1e-08 35.8 0.0 5.4e-05 23.6 0.0 3.5 2 1 0 2 2 2 2 SET domain Glyco_transf_25 PF01755.17 OEU08965.1 - 1.3e-13 51.3 0.2 1e-11 45.1 0.2 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pox_P35 PF03213.14 OEU08965.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein TMP-TENI PF02581.17 OEU08967.1 - 3.4e-11 42.8 2.8 4.6e-11 42.4 0.8 2.2 2 1 0 2 2 2 1 Thiamine monophosphate synthase SLM4 PF16818.5 OEU08967.1 - 0.0062 16.5 1.4 0.012 15.6 1.4 1.4 1 0 0 1 1 1 1 Protein SLM4 DUF4942 PF13708.6 OEU08967.1 - 0.028 14.4 3.8 0.042 13.8 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) DUF2347 PF09804.9 OEU08967.1 - 0.039 13.6 0.6 0.058 13.0 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) ThylakoidFormat PF11264.8 OEU08968.1 - 1.6e-51 175.0 0.0 1.6e-51 175.0 0.0 1.5 2 0 0 2 2 2 1 Thylakoid formation protein GAGE PF05831.11 OEU08969.1 - 0.015 15.8 2.0 0.041 14.4 2.0 1.7 1 0 0 1 1 1 0 GAGE protein Folate_carrier PF01770.18 OEU08969.1 - 1 8.0 4.4 0.38 9.5 0.1 1.9 1 1 1 2 2 2 0 Reduced folate carrier Pterin_4a PF01329.19 OEU08970.1 - 2.6e-30 104.4 0.2 4.5e-30 103.7 0.2 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Aminotran_1_2 PF00155.21 OEU08971.1 - 3.1e-47 161.5 0.0 3.7e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OEU08971.1 - 0.0048 15.5 0.0 0.0081 14.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OEU08971.1 - 0.029 13.3 0.0 0.056 12.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_MocR PF12897.7 OEU08971.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF1115 PF06544.12 OEU08972.1 - 0.0044 17.1 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PC-Esterase PF13839.6 OEU08973.1 - 4.5e-16 59.4 4.6 4.7e-08 33.1 2.3 3.8 2 2 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.6 OEU08973.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Phage_T4_Gp30_7 PF06919.11 OEU08973.1 - 0.057 13.6 0.1 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage Gp30.7 protein PfkB PF00294.24 OEU08974.1 - 2.7e-30 105.7 0.3 5.3e-30 104.8 0.3 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.24 OEU08974.1 - 2e-20 73.1 0.0 4.8e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF4768 PF15989.5 OEU08974.1 - 0.12 12.3 1.3 0.28 11.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4768) DUF1292 PF06949.11 OEU08974.1 - 5.1 8.1 5.3 5.7 8.0 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) Mito_carr PF00153.27 OEU08976.1 - 1.6e-49 165.8 6.8 2.8e-19 68.8 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 OEU08976.1 - 0.00042 19.6 0.8 0.14 11.3 0.0 2.7 2 1 1 3 3 3 2 Gammaproteobacterial serine protease KptA_kDCL PF18176.1 OEU08976.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain RCC1 PF00415.18 OEU08977.1 - 1.7e-30 105.4 4.7 2.6e-09 37.6 0.1 6.2 5 1 1 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU08977.1 - 2.5e-26 90.8 14.0 1.7e-07 30.8 0.0 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OEU08977.1 - 0.021 14.6 0.1 2.7 7.7 0.1 2.7 2 1 1 3 3 3 0 TUP1-like enhancer of split Glyco_hydro_99 PF16317.5 OEU08978.1 - 2.9e-21 76.0 2.6 5.7e-21 75.0 2.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 OEU08978.1 - 0.029 13.8 0.1 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase WbsX zf-MYND PF01753.18 OEU08979.1 - 5.9e-07 29.5 11.0 5.9e-07 29.5 11.0 1.7 2 0 0 2 2 2 1 MYND finger SET PF00856.28 OEU08979.1 - 5e-06 27.0 0.1 0.00057 20.3 0.1 2.2 1 1 0 1 1 1 1 SET domain DUF2913 PF11140.8 OEU08979.1 - 0.081 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) mTERF PF02536.14 OEU08980.1 - 1.5e-08 34.0 0.0 2.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 mTERF SSP160 PF06933.11 OEU08981.1 - 0.052 11.8 17.7 0.065 11.4 17.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Apt1 PF10351.9 OEU08981.1 - 1.1 8.1 12.5 1.3 7.8 12.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Proteasome PF00227.26 OEU08982.1 - 2.7e-29 102.0 0.1 3.1e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit 7tm_3 PF00003.22 OEU08983.1 - 3e-33 115.5 20.5 4.2e-33 115.1 20.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OEU08983.1 - 3.8e-11 42.7 0.1 2.4e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OEU08983.1 - 0.0076 16.0 0.1 0.02 14.6 0.1 1.7 1 1 0 1 1 1 1 Periplasmic binding protein DUF2304 PF10066.9 OEU08983.1 - 2 8.7 12.0 0.58 10.4 6.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF1275 PF06912.11 OEU08984.1 - 7.8e-13 48.8 12.1 1.5e-12 47.9 11.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) EF-hand_5 PF13202.6 OEU08984.1 - 7e-10 38.0 1.2 2.6e-07 29.8 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OEU08984.1 - 2.2e-08 33.1 1.8 6.7e-05 22.2 0.0 3.3 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 OEU08984.1 - 8.6e-07 28.4 2.9 0.0028 17.4 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OEU08984.1 - 3.1e-06 27.6 1.6 2.3e-05 24.7 0.9 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OEU08984.1 - 5.6e-05 22.9 4.1 0.00014 21.6 0.4 2.6 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU08984.1 - 0.0043 17.3 0.1 0.0077 16.5 0.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OEU08984.1 - 0.0097 15.7 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 EF hand Colicin_V PF02674.16 OEU08984.1 - 8.2 6.4 16.5 0.15 12.0 4.9 2.8 2 1 1 3 3 3 0 Colicin V production protein MAGI_u1 PF16663.5 OEU08985.1 - 0.9 9.7 6.2 0.11 12.6 1.3 2.1 2 0 0 2 2 2 0 Unstructured region on MAGI TSP9 PF11493.8 OEU08986.1 - 2.7 8.7 5.7 1.3 9.7 0.1 2.9 3 0 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 Cpn60_TCP1 PF00118.24 OEU08987.1 - 2.2e-158 527.9 3.0 2.6e-158 527.7 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family THF_DHG_CYH_C PF02882.19 OEU08987.1 - 0.052 12.9 0.1 0.12 11.6 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 OEU08988.1 - 7.1e-34 117.3 13.4 8.2e-28 97.3 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GET2 PF08690.10 OEU08988.1 - 0.052 13.2 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Pro_isomerase PF00160.21 OEU08990.1 - 0.035 14.4 0.0 0.063 13.5 0.0 1.5 1 1 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1275 PF06912.11 OEU08991.1 - 1.9e-09 37.7 9.5 1.9e-09 37.7 9.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1275) SPC25 PF06703.11 OEU08991.1 - 0.0075 16.1 0.2 0.019 14.8 0.2 1.7 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) SUIM_assoc PF16619.5 OEU08991.1 - 3.5 7.8 5.3 13 5.9 5.3 1.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PT PF04886.12 OEU08993.1 - 4.2e-17 61.4 129.3 4.4e-06 26.1 20.5 8.1 3 2 1 4 4 4 2 PT repeat Hexapep PF00132.24 OEU08993.1 - 0.35 10.7 13.8 6.2 6.7 0.3 4.9 4 0 0 4 4 4 0 Bacterial transferase hexapeptide (six repeats) LRR_4 PF12799.7 OEU08994.1 - 0.48 10.9 9.4 1.8 9.1 3.9 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU08994.1 - 0.82 10.5 8.1 8.1 7.4 0.3 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat NID PF07292.13 OEU08994.1 - 5.9 7.6 9.1 8.6 7.1 1.1 2.8 2 1 0 2 2 2 0 Nmi/IFP 35 domain (NID) Mucin PF01456.17 OEU08994.1 - 6.9 6.7 23.6 2.2 8.3 3.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PDZ PF00595.24 OEU08995.1 - 0.0083 16.5 0.3 0.019 15.3 0.3 1.7 1 0 0 1 1 1 1 PDZ domain DUF460 PF04312.13 OEU08995.1 - 0.058 13.1 0.9 0.12 12.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF460) YL1 PF05764.13 OEU08995.1 - 1.4 9.0 22.8 5.8 7.0 22.8 1.8 1 1 0 1 1 1 0 YL1 nuclear protein Collagen_bind_2 PF12904.7 OEU08996.1 - 0.099 12.6 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Imm2 PF14426.6 OEU08997.1 - 0.1 12.7 0.3 0.64 10.1 0.3 2.0 1 1 0 1 1 1 0 Immunity protein Imm2 2OG-FeII_Oxy PF03171.20 OEU08998.1 - 4.6e-05 23.8 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.9 OEU08998.1 - 0.016 14.8 18.5 0.04 13.5 7.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HSF_DNA-bind PF00447.17 OEU09000.1 - 2.1e-18 66.7 0.0 2.3e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding SET_assoc PF11767.8 OEU09000.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated 2OG-FeII_Oxy_2 PF13532.6 OEU09001.1 - 6.1e-18 65.7 0.0 6.7e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4834 PF16118.5 OEU09002.1 - 0.1 13.6 0.1 0.1 13.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 OEU09002.1 - 0.14 13.1 1.6 0.76 10.7 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Fasciclin PF02469.22 OEU09004.1 - 1e-34 119.5 0.0 1.2e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain SET PF00856.28 OEU09005.1 - 3.8e-11 43.7 2.4 4.7e-11 43.4 0.2 2.3 2 1 1 3 3 3 2 SET domain GILT PF03227.16 OEU09006.1 - 8.4e-27 93.5 0.5 8.4e-27 93.5 0.5 2.0 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Sporozoite_P67 PF05642.11 OEU09006.1 - 0.037 12.1 5.4 0.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen COP-gamma_platf PF08752.10 OEU09006.1 - 0.042 14.0 2.3 0.14 12.3 1.8 2.2 2 1 0 2 2 2 0 Coatomer gamma subunit appendage platform subdomain DUF2613 PF11021.8 OEU09006.1 - 0.063 13.4 7.3 0.25 11.5 7.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF3682 PF12446.8 OEU09006.1 - 2.3 8.7 7.4 1.5 9.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) 3Beta_HSD PF01073.19 OEU09007.1 - 0.029 13.4 0.0 0.06 12.3 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OEU09007.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1336 PF07059.12 OEU09008.1 - 2.1e-07 31.2 0.0 4.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) CRAL_TRIO PF00650.20 OEU09008.1 - 0.0068 16.1 0.1 9.2 6.0 0.0 3.2 3 0 0 3 3 3 2 CRAL/TRIO domain DUF1841 PF08897.11 OEU09010.1 - 0.13 12.2 0.0 10 6.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1841) EF-hand_7 PF13499.6 OEU09012.1 - 3.2e-06 27.5 4.8 0.003 18.0 0.6 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU09012.1 - 1.2e-05 24.8 5.1 0.015 15.2 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OEU09012.1 - 0.00021 20.6 6.9 0.0054 16.2 0.1 3.9 4 1 0 4 4 4 2 EF hand DUF835 PF05763.12 OEU09012.1 - 0.065 13.0 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF835) Thioredoxin PF00085.20 OEU09013.1 - 1.5e-12 47.4 0.1 1.7e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OEU09013.1 - 0.0015 18.0 0.0 0.0016 17.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OEU09013.1 - 0.0054 17.2 0.1 0.019 15.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU09013.1 - 0.0082 16.4 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU09013.1 - 0.085 12.8 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 OEU09013.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain YabA PF06156.13 OEU09014.1 - 0.00077 20.1 2.5 0.00077 20.1 2.5 1.8 1 1 1 2 2 2 1 Initiation control protein YabA HALZ PF02183.18 OEU09014.1 - 0.00095 19.3 4.3 0.00095 19.3 4.3 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper Spc29 PF17082.5 OEU09014.1 - 0.0073 16.2 2.9 0.0079 16.1 2.9 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 NRBF2 PF08961.10 OEU09014.1 - 0.034 13.8 9.5 0.052 13.2 9.5 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 OEU09014.1 - 0.052 13.7 3.3 0.052 13.7 3.3 2.7 1 1 2 3 3 3 0 bZIP transcription factor AKNA PF12443.8 OEU09014.1 - 0.052 14.2 5.1 0.19 12.4 2.8 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor TSC22 PF01166.18 OEU09014.1 - 0.063 13.6 4.9 0.26 11.6 4.9 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family TSNAXIP1_N PF15739.5 OEU09014.1 - 0.21 12.0 6.7 0.17 12.2 4.3 2.0 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Nup88 PF10168.9 OEU09014.1 - 0.47 8.2 7.3 0.57 7.9 7.3 1.0 1 0 0 1 1 1 0 Nuclear pore component FUSC PF04632.12 OEU09014.1 - 0.86 8.1 2.2 1 7.8 2.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cgr1 PF03879.14 OEU09014.1 - 4.8 7.6 10.4 20 5.6 10.4 2.3 1 1 0 1 1 1 0 Cgr1 family DivIC PF04977.15 OEU09014.1 - 6.3 6.6 10.3 3.1 7.6 4.6 2.4 1 1 1 2 2 2 0 Septum formation initiator HSF_DNA-bind PF00447.17 OEU09015.1 - 2.7e-18 66.4 0.1 6.9e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding PD40 PF07676.12 OEU09015.1 - 0.067 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Bac_rhamnosid_C PF17390.2 OEU09018.1 - 0.00086 19.1 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Ank_2 PF12796.7 OEU09019.1 - 1.4e-10 41.6 5.9 0.00014 22.3 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OEU09019.1 - 3.7e-08 33.5 0.0 0.022 15.2 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OEU09019.1 - 1.7e-07 30.9 4.4 0.0055 17.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OEU09019.1 - 4.4e-07 30.3 2.6 0.036 14.7 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU09019.1 - 1.2e-05 25.5 9.8 0.00075 19.7 0.3 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Apolipoprotein PF01442.18 OEU09020.1 - 5.2e-08 33.0 13.2 0.00011 22.2 5.9 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Nbl1_Borealin_N PF10444.9 OEU09020.1 - 0.0036 16.9 3.6 0.81 9.4 0.5 2.5 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal AAA_32 PF13654.6 OEU09020.1 - 0.029 13.2 8.8 0.04 12.7 8.8 1.3 1 0 0 1 1 1 0 AAA domain DUF1640 PF07798.11 OEU09020.1 - 0.11 12.6 8.8 0.22 11.6 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF883 PF05957.13 OEU09020.1 - 0.16 12.6 11.6 0.13 12.8 3.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 OEU09020.1 - 0.17 12.4 18.7 1.2 9.7 4.5 3.9 1 1 2 3 3 3 0 YtxH-like protein DUF3320 PF11784.8 OEU09020.1 - 0.27 11.2 4.5 0.89 9.6 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3320) Phasin PF05597.11 OEU09020.1 - 0.46 10.5 19.0 0.63 10.0 3.0 3.2 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SH3_17 PF18350.1 OEU09020.1 - 1.2 9.1 5.5 4.9 7.1 1.0 2.9 2 0 0 2 2 2 0 Restriction endonuclease SH3 domain dCache_2 PF08269.11 OEU09020.1 - 2 7.5 13.5 1.2 8.2 1.6 2.4 1 1 1 2 2 2 0 Cache domain DUF3135 PF11333.8 OEU09020.1 - 2 8.7 9.9 0.88 9.9 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) HSCB_C PF07743.13 OEU09020.1 - 2.2 8.8 9.2 4.5 7.8 0.4 2.7 2 1 1 3 3 2 0 HSCB C-terminal oligomerisation domain Phage_Mu_Gam PF07352.12 OEU09020.1 - 2.3 8.1 12.1 3.6 7.5 2.3 2.8 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Mpv17_PMP22 PF04117.12 OEU09021.1 - 5.4e-11 42.5 1.8 5.4e-11 42.5 1.8 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family PCMT PF01135.19 OEU09022.1 - 2.2e-28 99.5 0.0 5.2e-20 72.1 0.0 2.4 2 1 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OEU09022.1 - 0.00022 21.1 0.2 0.083 12.7 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OEU09022.1 - 0.00034 20.5 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU09022.1 - 0.00044 20.3 0.2 0.011 15.8 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU09022.1 - 0.00054 20.6 0.5 0.89 10.3 0.3 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OEU09022.1 - 0.0012 19.5 0.1 0.89 10.2 0.1 2.6 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 OEU09022.1 - 0.0033 17.0 0.1 0.0085 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain CENP-B_dimeris PF09026.10 OEU09022.1 - 0.0058 17.0 3.9 0.0058 17.0 3.9 2.9 3 0 0 3 3 2 1 Centromere protein B dimerisation domain Mucin PF01456.17 OEU09022.1 - 0.043 13.8 6.2 0.075 13.0 6.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein AviRa PF11599.8 OEU09022.1 - 0.043 13.3 0.1 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa DUF3439 PF11921.8 OEU09022.1 - 0.085 12.8 2.2 0.15 12.1 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DNA_pol_phi PF04931.13 OEU09022.1 - 0.53 8.3 8.1 0.76 7.8 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 OEU09022.1 - 0.94 7.9 4.9 1.3 7.5 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PI3K_1B_p101 PF10486.9 OEU09022.1 - 2 6.1 4.3 2.3 5.9 4.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Corazonin PF17308.2 OEU09022.1 - 3.3 8.1 12.0 4.3 7.7 1.3 2.5 2 1 0 2 2 2 0 Pro-corazonin NOA36 PF06524.12 OEU09022.1 - 4.1 6.7 15.7 0.14 11.4 9.7 1.5 2 0 0 2 2 2 0 NOA36 protein Methyltransf_12 PF08242.12 OEU09022.1 - 5.6 7.8 6.6 2.6 8.8 0.5 3.1 2 1 0 2 2 2 0 Methyltransferase domain DUF4611 PF15387.6 OEU09022.1 - 9.7 6.5 11.0 1.8 8.9 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DpnD-PcfM PF14207.6 OEU09023.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 DpnD/PcfM-like protein 7TM_GPCR_Srv PF10323.9 OEU09023.1 - 0.2 11.0 0.8 0.28 10.5 0.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv His_Phos_1 PF00300.22 OEU09024.1 - 7.8e-14 51.8 0.1 1.2e-05 25.1 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4064 PF13273.6 OEU09025.1 - 0.0096 16.2 5.2 0.0096 16.2 5.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) Amastin PF07344.11 OEU09025.1 - 0.43 10.4 5.2 0.1 12.5 1.1 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein PMSR PF01625.21 OEU09028.1 - 7.4e-13 48.9 1.3 8.5e-13 48.8 1.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LUD_dom PF02589.15 OEU09030.1 - 0.043 13.5 0.3 0.054 13.2 0.3 1.2 1 0 0 1 1 1 0 LUD domain RRF PF01765.19 OEU09030.1 - 0.13 12.2 3.9 0.24 11.4 3.2 1.7 2 0 0 2 2 2 0 Ribosome recycling factor DUF2884 PF11101.8 OEU09030.1 - 0.16 11.5 1.1 0.24 10.9 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) PH_RBD PF12068.8 OEU09031.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.8 3 0 0 3 3 3 0 Rab-binding domain (RBD) Methyltransf_4 PF02390.17 OEU09032.1 - 2.9e-10 39.9 1.5 1.2e-07 31.4 1.1 3.4 2 1 0 2 2 2 1 Putative methyltransferase INSIG PF07281.12 OEU09032.1 - 0.22 11.1 0.0 0.42 10.2 0.0 1.5 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) 4HBT_2 PF13279.6 OEU09033.1 - 8.9e-18 64.9 0.5 1.2e-17 64.6 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OEU09033.1 - 2e-05 24.0 3.7 3.3e-05 23.3 3.7 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT PF03061.22 OEU09033.1 - 5.6e-05 23.4 0.0 8.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily LRR_4 PF12799.7 OEU09034.1 - 7.4e-06 26.2 9.8 0.00092 19.6 1.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU09034.1 - 0.00098 18.8 10.6 0.039 13.7 6.3 3.3 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 OEU09034.1 - 0.076 13.1 2.3 7.6 6.9 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OEU09034.1 - 9 7.3 11.6 20 6.2 0.5 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 OEU09035.1 - 7.2e-08 32.1 1.5 1.2e-07 31.4 1.5 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OEU09035.1 - 0.0018 18.6 5.3 0.042 14.3 0.3 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU09035.1 - 0.48 11.2 2.7 74 4.5 0.0 3.6 2 1 0 2 2 2 0 Leucine Rich Repeat TetR_C_22 PF17928.1 OEU09036.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Casc1 PF12366.8 OEU09038.1 - 0.044 13.3 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Arm-DNA-bind_5 PF17293.2 OEU09038.1 - 0.044 14.2 2.3 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Atg14 PF10186.9 OEU09038.1 - 0.46 9.5 8.3 0.53 9.3 8.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DMPK_coil PF08826.10 OEU09038.1 - 1 9.6 9.7 0.1 12.7 2.4 2.7 3 0 0 3 3 3 0 DMPK coiled coil domain like HR1 PF02185.16 OEU09038.1 - 1 9.5 10.3 0.8 9.9 5.4 2.3 2 0 0 2 2 2 0 Hr1 repeat NYD-SP28_assoc PF14775.6 OEU09038.1 - 2.9 8.1 7.5 0.95 9.6 0.8 2.5 2 1 0 2 2 2 0 Sperm tail C-terminal domain SlyX PF04102.12 OEU09038.1 - 3.4 8.4 8.4 2.7 8.7 4.8 2.1 2 0 0 2 2 2 0 SlyX Stealth_CR4 PF17103.5 OEU09039.1 - 0.032 14.1 1.2 0.061 13.2 0.6 1.8 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 DDE_1 PF03184.19 OEU09040.1 - 5e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease OSCP PF00213.18 OEU09040.1 - 0.069 13.3 0.1 0.26 11.4 0.1 2.0 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Methyltransf_12 PF08242.12 OEU09041.1 - 0.16 12.7 0.0 0.36 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DDE_Tnp_1_7 PF13843.6 OEU09044.1 - 1.7e-15 57.2 0.1 3.3e-15 56.2 0.1 1.5 1 1 0 1 1 1 1 Transposase IS4 Swi5 PF07061.11 OEU09046.1 - 2.4 8.3 9.1 13 6.0 1.6 3.9 2 1 0 2 2 2 0 Swi5 Prefoldin PF02996.17 OEU09046.1 - 3.8 7.4 16.1 1.2 9.0 6.1 3.0 2 1 0 2 2 2 0 Prefoldin subunit Heme_oxygenase PF01126.20 OEU09048.1 - 2.6e-53 180.9 0.0 3.7e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase DUF1091 PF06477.13 OEU09048.1 - 0.005 17.3 0.5 0.33 11.4 0.1 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1091) zf-CHC2 PF01807.20 OEU09048.1 - 4.8 7.1 5.2 2.4 8.0 0.2 2.9 3 0 0 3 3 3 0 CHC2 zinc finger Macoilin PF09726.9 OEU09048.1 - 10 4.6 7.2 15 4.0 7.2 1.3 1 0 0 1 1 1 0 Macoilin family Ctr PF04145.15 OEU09049.1 - 7.5e-17 62.3 11.5 2.6e-16 60.6 11.5 1.8 1 1 0 1 1 1 1 Ctr copper transporter family HemY_N PF07219.13 OEU09049.1 - 0.016 15.4 0.2 0.016 15.4 0.2 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Anoctamin PF04547.12 OEU09049.1 - 0.07 12.0 1.7 5.4 5.7 0.2 2.0 1 1 1 2 2 2 0 Calcium-activated chloride channel DUF443 PF04276.12 OEU09049.1 - 0.12 12.2 3.0 0.84 9.4 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF443) EpuA PF11772.8 OEU09049.1 - 0.15 11.7 3.1 0.34 10.6 3.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta LapA_dom PF06305.11 OEU09049.1 - 0.97 9.3 3.4 32 4.5 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain E1-E2_ATPase PF00122.20 OEU09050.1 - 2.7e-40 137.8 0.7 7.3e-40 136.4 0.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OEU09050.1 - 1.6e-30 106.9 0.2 2.6e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OEU09050.1 - 3.2e-24 85.1 4.0 4.1e-11 43.2 0.0 3.4 4 0 0 4 4 4 2 Heavy-metal-associated domain Ribosomal_S13 PF00416.22 OEU09050.1 - 0.015 15.7 1.5 0.85 10.0 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein S13/S18 PSA_CBD PF18341.1 OEU09050.1 - 0.12 12.4 1.4 0.81 9.8 0.3 2.6 3 0 0 3 3 3 0 PSA endolysin C-terminal cell wall binding domain HAD PF12710.7 OEU09050.1 - 0.15 12.5 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OEU09050.1 - 0.2 11.3 0.6 1 9.0 0.2 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Carb_anhydrase PF00194.21 OEU09051.1 - 1.4e-15 57.5 1.1 5.3e-12 45.8 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase FBPase PF00316.20 OEU09052.1 - 1.6e-46 158.1 0.2 2.5e-46 157.6 0.2 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain FBPase PF00316.20 OEU09053.1 - 2.5e-41 141.2 0.2 3.6e-41 140.7 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Rxt3 PF08642.10 OEU09054.1 - 7.6 7.3 8.6 16 6.3 1.6 2.3 1 1 0 2 2 2 0 Histone deacetylation protein Rxt3 Phage_CI_repr PF07022.13 OEU09055.1 - 0.029 14.4 0.1 5.2 7.2 0.0 2.9 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Sld3_N PF18523.1 OEU09055.1 - 0.032 14.4 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Sld3 N-terminal domain AAA_18 PF13238.6 OEU09055.1 - 0.14 12.7 0.1 7.5 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Chlorophyllase2 PF12740.7 OEU09057.1 - 5.9e-05 22.1 0.0 9.6e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OEU09057.1 - 0.011 15.0 0.0 0.34 10.1 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Retrotran_gag_2 PF14223.6 OEU09058.1 - 0.0042 16.8 0.2 0.0073 16.0 0.2 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type TMEM154 PF15102.6 OEU09059.1 - 0.012 15.6 1.4 0.012 15.6 1.4 1.4 2 0 0 2 2 2 0 TMEM154 protein family ADH_zinc_N PF00107.26 OEU09060.1 - 1.6e-14 54.0 0.0 7.3e-14 51.9 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU09060.1 - 3.3e-07 31.4 0.0 0.00089 20.3 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Inhibitor_I71 PF12628.7 OEU09060.1 - 0.0082 16.0 0.2 0.017 14.9 0.2 1.6 1 0 0 1 1 1 1 Falstatin, cysteine peptidase inhibitor FAM176 PF14851.6 OEU09060.1 - 0.59 9.8 2.3 1.2 8.8 2.3 1.4 1 0 0 1 1 1 0 FAM176 family PorA PF11271.8 OEU09061.1 - 0.47 9.7 3.4 0.93 8.7 3.4 1.5 1 0 0 1 1 1 0 Porin PorA Myb_DNA-binding PF00249.31 OEU09062.1 - 5.1e-15 55.4 1.2 1.1e-14 54.3 1.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU09062.1 - 6.2e-11 42.4 0.4 6.2e-11 42.4 0.4 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF736 PF05284.12 OEU09063.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Radial_spoke_3 PF06098.11 OEU09064.1 - 0.0011 18.3 1.8 0.0019 17.5 1.8 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 ADP_PFK_GK PF04587.15 OEU09064.1 - 0.029 12.9 0.2 0.04 12.5 0.2 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region zf-rbx1 PF12678.7 OEU09065.1 - 5.8e-10 39.3 4.6 5.8e-10 39.3 4.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OEU09065.1 - 1.4e-08 35.0 8.0 1.4e-08 35.0 8.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 OEU09065.1 - 8.2e-07 29.0 2.0 8.2e-07 29.0 2.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OEU09065.1 - 9e-07 28.6 5.9 9e-07 28.6 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU09065.1 - 0.0002 21.2 8.3 0.0002 21.2 8.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU09065.1 - 0.00062 19.7 5.0 0.00062 19.7 5.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING-like PF08746.11 OEU09065.1 - 0.00064 20.0 5.0 0.00064 20.0 5.0 2.0 2 1 0 2 2 1 1 RING-like domain zf-C3HC4_3 PF13920.6 OEU09065.1 - 0.006 16.4 3.6 0.006 16.4 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU09065.1 - 0.0061 16.3 3.2 0.0061 16.3 3.2 2.7 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OEU09065.1 - 0.02 14.5 3.3 0.02 14.5 3.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OEU09065.1 - 0.024 14.7 5.3 0.024 14.7 5.3 2.8 2 1 1 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.8 OEU09065.1 - 0.45 10.7 13.5 0.061 13.5 5.0 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OEU09065.1 - 1.7 8.6 12.9 0.043 13.7 5.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RCDG1 PF15725.5 OEU09065.1 - 2.6 8.5 6.1 0.82 10.1 0.2 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Peptidase_S51 PF03575.17 OEU09066.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 HA PF03457.14 OEU09068.1 - 4e-40 136.0 3.8 7.8e-19 67.8 0.1 3.0 2 1 1 3 3 3 3 Helicase associated domain CRF1 PF10380.9 OEU09068.1 - 0.18 12.1 0.0 26 5.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor CRF1 PBP1_TM PF14812.6 OEU09069.1 - 0.027 14.8 0.5 0.036 14.4 0.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.18 OEU09069.1 - 0.047 13.6 3.8 0.055 13.4 3.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PDZ_assoc PF10600.9 OEU09069.1 - 0.057 14.3 3.2 0.079 13.8 2.8 1.5 1 1 0 1 1 1 0 PDZ-associated domain of NMDA receptors RXT2_N PF08595.11 OEU09069.1 - 0.066 13.2 1.7 0.081 12.9 1.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF5090 PF17009.5 OEU09069.1 - 0.14 12.1 0.3 0.2 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) NESP55 PF06390.12 OEU09069.1 - 0.36 10.4 5.4 0.45 10.1 5.4 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) ORC6 PF05460.13 OEU09069.1 - 0.41 9.9 4.3 0.44 9.8 4.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IPP-2 PF04979.14 OEU09069.1 - 2.5 8.8 9.8 0.5 11.1 5.8 1.7 1 1 1 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) FAM176 PF14851.6 OEU09071.1 - 0.014 15.1 1.5 0.2 11.3 1.3 2.3 2 0 0 2 2 2 0 FAM176 family E7 PF00527.18 OEU09071.1 - 0.067 13.4 0.2 0.3 11.3 0.1 2.2 2 0 0 2 2 2 0 E7 protein, Early protein DNA_pol_phi PF04931.13 OEU09071.1 - 0.079 11.1 7.1 0.11 10.5 7.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 OEU09071.1 - 0.58 9.2 13.1 1.1 8.3 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 OEU09071.1 - 1.5 8.9 7.2 0.71 9.9 4.2 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 OEU09071.1 - 2.9 8.3 20.2 0.057 13.8 10.4 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CDC45 PF02724.14 OEU09071.1 - 5.7 5.1 6.8 8.6 4.5 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein HA PF03457.14 OEU09072.1 - 1.2e-35 121.6 1.2 1.4e-16 60.6 0.0 2.0 2 0 0 2 2 2 2 Helicase associated domain Ilm1 PF10311.9 OEU09072.1 - 0.047 13.3 0.1 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF5522 PF17653.1 OEU09072.1 - 0.062 13.3 0.2 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5522) CRF1 PF10380.9 OEU09072.1 - 0.11 12.9 0.1 17 5.8 0.0 2.2 1 1 1 2 2 2 0 Transcription factor CRF1 DUF3340 PF11818.8 OEU09072.1 - 0.12 12.5 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Topo_C_assoc PF14370.6 OEU09072.1 - 0.38 10.7 3.2 0.93 9.5 0.7 2.3 1 1 1 2 2 2 0 C-terminal topoisomerase domain Choline_transpo PF04515.12 OEU09073.1 - 6.3 5.9 6.2 7.6 5.6 6.2 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter zf-MYND PF01753.18 OEU09075.1 - 8.1e-07 29.0 8.8 8.1e-07 29.0 8.8 2.0 2 0 0 2 2 2 1 MYND finger TPR_2 PF07719.17 OEU09076.1 - 0.0068 16.4 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Voldacs PF03517.13 OEU09076.1 - 0.32 11.1 5.7 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 OEU09076.1 - 0.52 9.6 12.8 1.5 8.1 1.9 2.2 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 OEU09076.1 - 3.2 8.2 17.5 3.2 8.2 4.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 OEU09076.1 - 6.7 7.0 11.2 10 6.4 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Autophagy_N PF03986.13 OEU09077.1 - 4.8e-33 114.0 6.0 4.8e-33 114.0 6.0 2.5 2 1 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OEU09077.1 - 8.3e-17 61.5 2.1 1.5e-16 60.7 2.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OEU09077.1 - 4e-13 48.6 4.0 8.5e-13 47.6 4.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal RskA PF10099.9 OEU09077.1 - 0.073 13.4 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF5643 PF18705.1 OEU09077.1 - 1.2 9.1 8.3 0.38 10.7 3.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Glyoxalase PF00903.25 OEU09078.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OEU09078.1 - 0.1 12.5 0.1 4.7 7.2 0.1 2.8 1 1 0 1 1 1 0 Glyoxalase-like domain LRR_6 PF13516.6 OEU09079.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 OEU09079.1 - 0.3 11.6 0.0 0.3 11.6 0.0 5.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF4519 PF15012.6 OEU09080.1 - 1.6 9.0 12.4 3.9 7.7 11.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) NuA4 PF09340.10 OEU09081.1 - 0.79 9.6 4.1 20 5.2 0.6 2.9 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 SR-25 PF10500.9 OEU09081.1 - 1.3 8.6 9.0 0.03 13.9 1.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF520 PF04461.13 OEU09082.1 - 0.021 14.9 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) AvrE_T3Es PF11725.8 OEU09082.1 - 0.24 8.6 0.0 0.29 8.3 0.0 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) zf-MYND PF01753.18 OEU09084.1 - 0.00092 19.2 19.0 0.0049 16.9 19.0 2.3 1 1 0 1 1 1 1 MYND finger Tex_YqgF PF16921.5 OEU09086.1 - 6.7e-25 88.0 0.0 2.7e-15 56.9 0.0 2.8 1 1 1 2 2 2 2 Tex protein YqgF-like domain HHH_3 PF12836.7 OEU09086.1 - 4.8e-14 52.3 0.0 1.4e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OEU09086.1 - 7.2e-12 45.3 0.1 4.9e-10 39.4 0.1 2.7 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 RVT_1 PF00078.27 OEU09086.1 - 1.7e-06 27.8 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HHH_9 PF17674.1 OEU09086.1 - 1e-05 26.3 0.0 5.5e-05 24.0 0.0 2.4 1 0 0 1 1 1 1 HHH domain HHH_7 PF14635.6 OEU09086.1 - 4.4e-05 23.8 0.0 0.00014 22.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 OEU09086.1 - 0.018 15.4 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain DUF285 PF03382.14 OEU09087.1 - 3.1e-72 240.0 44.6 8e-33 112.8 14.4 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DrrA_P4M PF14860.6 OEU09087.1 - 0.038 13.8 1.8 12 5.8 0.0 3.5 1 1 3 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain Cytochrom_B_C PF00032.17 OEU09089.1 - 0.23 11.7 3.4 0.14 12.4 0.6 2.1 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Aa_trans PF01490.18 OEU09090.1 - 7.6e-22 77.6 6.3 1.2e-21 76.9 6.3 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Zip PF02535.22 OEU09090.1 - 0.0067 15.7 0.2 0.0067 15.7 0.2 2.3 2 1 1 3 3 3 1 ZIP Zinc transporter PAP2 PF01569.21 OEU09093.1 - 4.7e-06 26.4 0.5 2.4e-05 24.1 0.1 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF5362 PF17319.2 OEU09093.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) PhoLip_ATPase_C PF16212.5 OEU09094.1 - 0.0056 16.5 0.0 0.0079 16.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 OEU09094.1 - 0.0071 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3446 PF11928.8 OEU09094.1 - 0.27 11.6 5.6 5.5 7.4 0.4 2.8 2 1 1 3 3 3 0 Early growth response N-terminal domain Asp PF00026.23 OEU09097.1 - 3.4e-18 66.1 0.0 3.8e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OEU09097.1 - 8.6e-05 22.8 0.0 0.0002 21.6 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal ABC_tran PF00005.27 OEU09100.1 - 1.7e-27 96.6 0.1 3.2e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OEU09100.1 - 3.9e-25 88.5 22.6 1.2e-24 86.9 22.6 1.8 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OEU09100.1 - 3.1e-12 46.3 24.3 5.4e-12 45.5 24.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OEU09100.1 - 0.00013 21.9 0.5 0.022 14.6 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU09100.1 - 0.00052 19.9 0.3 0.0012 18.8 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 OEU09100.1 - 0.0027 17.2 0.1 0.02 14.3 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU09100.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 OEU09100.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 OEU09100.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OEU09100.1 - 0.12 12.4 0.5 0.58 10.3 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 OEU09100.1 - 0.15 11.3 11.7 0.25 10.6 11.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SRPRB PF09439.10 OEU09100.1 - 0.2 11.1 0.6 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Flavodoxin_1 PF00258.25 OEU09104.1 - 4.1e-18 65.9 0.2 5.8e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Flavodoxin DUF4366 PF14283.6 OEU09104.1 - 0.0023 18.0 0.1 0.008 16.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF1661 PF07877.11 OEU09104.1 - 0.024 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) PT PF04886.12 OEU09105.1 - 4.3 7.0 75.9 2.1 7.9 13.9 5.4 4 1 0 4 4 4 0 PT repeat Trypsin PF00089.26 OEU09106.1 - 5.4e-37 127.7 0.2 1.9e-36 126.0 0.2 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU09106.1 - 3e-06 28.2 0.0 7.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain SR-25 PF10500.9 OEU09106.1 - 3.6 7.1 10.8 5.8 6.5 10.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 OEU09108.1 - 0.17 10.4 6.2 0.21 10.0 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Importin_rep_2 PF18786.1 OEU09108.1 - 0.31 10.9 3.0 0.43 10.5 0.3 2.2 2 0 0 2 2 2 0 Importin 13 repeat YrhK PF14145.6 OEU09112.1 - 0.0022 17.8 0.7 0.1 12.5 0.0 2.2 2 0 0 2 2 2 2 YrhK-like protein LPMO_10 PF03067.15 OEU09113.1 - 1.5e-19 71.4 0.0 4.9e-19 69.7 0.0 1.9 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Chitin_bind_1 PF00187.19 OEU09113.1 - 3e-05 24.4 8.9 3e-05 24.4 8.9 2.4 2 0 0 2 2 2 1 Chitin recognition protein potato_inhibit PF00280.18 OEU09116.1 - 4.7e-05 24.0 0.6 0.0057 17.3 0.2 2.4 1 1 0 2 2 2 2 Potato inhibitor I family MOLO1 PF17175.4 OEU09116.1 - 0.014 15.5 0.2 0.018 15.2 0.2 1.1 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 Ank_2 PF12796.7 OEU09117.1 - 6e-15 55.6 0.0 1.6e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU09117.1 - 2.8e-14 53.3 1.6 1.7e-07 31.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU09117.1 - 1.1e-11 44.7 0.1 1.2e-05 25.5 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU09117.1 - 4.6e-10 38.8 0.0 1.5e-05 25.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OEU09117.1 - 2.6e-08 34.0 0.0 0.005 17.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat GP67 PF17634.2 OEU09117.1 - 0.022 15.2 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Gene product 67 CLP_protease PF00574.23 OEU09118.1 - 2.6e-72 242.6 0.1 3.3e-72 242.2 0.1 1.1 1 0 0 1 1 1 1 Clp protease 7tm_3 PF00003.22 OEU09120.1 - 9.1e-16 58.3 10.3 2e-15 57.2 10.3 1.6 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Radical_SAM PF04055.21 OEU09121.1 - 1.7e-27 96.8 0.1 2.9e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 OEU09121.1 - 1.6e-21 76.2 0.1 9.4e-21 73.7 0.1 2.2 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 OEU09121.1 - 1.9e-15 56.6 0.1 3.4e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 OEU09121.1 - 0.00049 20.2 0.1 0.0026 17.9 0.1 2.2 1 1 0 1 1 1 1 TRAM domain Fer4_12 PF13353.6 OEU09121.1 - 0.0017 18.6 0.1 0.0044 17.3 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lipase_GDSL_2 PF13472.6 OEU09121.1 - 0.14 12.6 0.0 0.99 9.8 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family HA PF03457.14 OEU09122.1 - 2.8e-41 139.7 4.9 4.9e-20 71.6 0.2 2.0 2 0 0 2 2 2 2 Helicase associated domain DUF3822 PF12864.7 OEU09122.1 - 0.0029 16.8 0.3 0.0086 15.3 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3822) DUF5522 PF17653.1 OEU09122.1 - 0.03 14.3 0.2 4.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5522) Helicase_IV_N PF12462.8 OEU09122.1 - 0.071 13.1 2.8 2.9 7.8 0.4 2.1 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal ABC_trans_N PF14510.6 OEU09122.1 - 0.083 13.5 0.8 0.94 10.1 0.1 2.3 2 1 0 2 2 2 0 ABC-transporter N-terminal Acetyltransf_1 PF00583.25 OEU09123.1 - 3.5e-07 30.5 0.0 0.0048 17.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 OEU09123.1 - 0.0064 16.4 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 OEU09123.1 - 0.0075 16.7 0.1 0.019 15.4 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU09123.1 - 0.014 15.3 0.0 0.11 12.4 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain NOA36 PF06524.12 OEU09123.1 - 3.2 7.0 14.6 5.1 6.3 6.9 2.4 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 OEU09123.1 - 3.2 8.2 14.0 2.5 8.5 0.6 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Aldedh PF00171.22 OEU09124.1 - 2.6e-133 444.9 0.0 3.2e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Profilin PF00235.19 OEU09125.1 - 0.027 14.7 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 Profilin Mito_fiss_reg PF05308.11 OEU09126.1 - 0.0011 19.1 4.5 0.0011 19.1 4.5 1.9 2 0 0 2 2 2 1 Mitochondrial fission regulator Chorion_3 PF05387.11 OEU09126.1 - 0.028 14.1 0.2 0.028 14.1 0.2 1.5 2 0 0 2 2 2 0 Chorion family 3 PIP5K PF01504.18 OEU09126.1 - 0.052 12.8 3.9 0.11 11.7 3.9 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PRIMA1 PF16101.5 OEU09126.1 - 1.5 8.9 9.2 0.077 13.0 3.6 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Chloroa_b-bind PF00504.21 OEU09127.1 - 8e-31 107.7 1.5 1.1e-30 107.3 1.5 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EspB PF05802.11 OEU09127.1 - 0.045 13.7 1.1 0.053 13.5 0.0 1.7 2 1 0 2 2 2 0 Enterobacterial EspB protein HA PF03457.14 OEU09131.1 - 9e-54 179.7 2.8 4.9e-17 62.0 0.0 3.0 3 0 0 3 3 3 3 Helicase associated domain PMR5N PF14416.6 OEU09131.1 - 0.067 13.5 0.3 42 4.6 0.0 3.3 3 0 0 3 3 3 0 PMR5 N terminal Domain zf-MYND PF01753.18 OEU09132.1 - 1.7e-07 31.2 12.4 3e-07 30.4 12.4 1.4 1 0 0 1 1 1 1 MYND finger Chloroa_b-bind PF00504.21 OEU09133.1 - 2.3e-34 119.3 0.0 3.1e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 OEU09134.1 - 3.7e-24 86.1 0.0 9.6e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein TssO PF17561.2 OEU09135.1 - 0.76 9.9 3.5 39 4.3 0.1 3.4 3 0 0 3 3 3 0 Type VI secretion system, TssO DUF948 PF06103.11 OEU09135.1 - 1 9.6 12.6 6.6 7.1 0.8 4.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMEM52 PF14979.6 OEU09135.1 - 3.9 7.4 5.7 0.82 9.6 0.1 2.7 3 0 0 3 3 3 0 Transmembrane 52 DUF3671 PF12420.8 OEU09135.1 - 4.1 7.5 15.7 14 5.8 3.5 4.9 4 1 1 5 5 5 0 Protein of unknown function ATP-synt_8 PF00895.20 OEU09135.1 - 5 7.7 6.5 6.4 7.3 0.1 3.8 3 0 0 3 3 3 0 ATP synthase protein 8 Macoilin PF09726.9 OEU09136.1 - 1.5 7.3 27.6 1.7 7.1 27.6 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OEU09136.1 - 8.5 5.9 40.7 2.4e+02 1.2 40.7 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein 2OG-FeII_Oxy_2 PF13532.6 OEU09137.1 - 8.3e-13 49.0 0.4 2.7e-12 47.3 0.4 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MscL PF01741.18 OEU09138.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF4330 PF14221.6 OEU09138.1 - 0.15 12.3 0.1 12 6.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4330) MmlI PF09448.10 OEU09139.1 - 0.1 13.0 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase DUF4579 PF15158.6 OEU09140.1 - 0.052 13.3 4.2 0.034 13.9 2.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) TFIIA PF03153.13 OEU09142.1 - 0.0031 17.6 2.5 0.0035 17.4 2.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OEU09142.1 - 0.077 11.7 0.8 0.1 11.3 0.8 1.2 1 0 0 1 1 1 0 Presenilin CBP_BcsG PF11658.8 OEU09142.1 - 0.13 10.7 4.5 0.18 10.2 4.5 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF5521 PF17659.1 OEU09142.1 - 0.92 7.3 8.0 1.2 6.9 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF3450 PF11932.8 OEU09142.1 - 1.1 8.5 12.1 1.1 8.6 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMEM154 PF15102.6 OEU09142.1 - 3 7.7 5.9 22 4.9 4.7 2.6 2 0 0 2 2 2 0 TMEM154 protein family Lyase_8_C PF02884.17 OEU09143.1 - 0.084 13.4 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain BUD22 PF09073.10 OEU09144.1 - 0.00066 19.1 26.1 0.00094 18.6 26.1 1.2 1 0 0 1 1 1 1 BUD22 Serinc PF03348.15 OEU09144.1 - 0.31 9.9 3.9 3.3 6.5 0.8 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) PAF-AH_p_II PF03403.13 OEU09146.1 - 1e-17 63.8 0.0 2.8e-16 59.0 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OEU09146.1 - 1.5e-06 27.3 0.0 3.5e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 OEU09146.1 - 0.00022 21.9 0.3 0.00032 21.4 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OEU09146.1 - 0.00083 18.5 0.0 0.04 12.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_3 PF07859.13 OEU09146.1 - 0.00089 19.2 0.0 0.0026 17.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU09146.1 - 0.0013 18.1 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OEU09146.1 - 0.071 11.8 0.0 0.14 10.8 0.0 1.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 OEU09146.1 - 0.16 11.5 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Sporozoite_P67 PF05642.11 OEU09147.1 - 0.067 11.3 7.2 0.095 10.8 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PDEase_I PF00233.19 OEU09149.1 - 1.7e-31 109.8 0.9 3.8e-31 108.6 0.9 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase F-box-like PF12937.7 OEU09150.1 - 5.6e-05 22.9 0.2 0.00013 21.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OEU09150.1 - 0.00029 20.7 1.4 0.00091 19.1 0.1 2.3 2 0 0 2 2 2 1 F-box F-box PF00646.33 OEU09150.1 - 0.038 13.9 1.4 0.12 12.2 1.4 1.9 1 1 0 1 1 1 0 F-box domain Peptidase_M54 PF07998.11 OEU09150.1 - 0.99 9.4 4.1 1.7 8.6 4.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 Ank_4 PF13637.6 OEU09154.1 - 0.034 14.7 0.1 3.3 8.4 0.0 3.0 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU09154.1 - 0.11 13.1 0.1 28 5.7 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat TrkA_N PF02254.18 OEU09154.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF3439 PF11921.8 OEU09156.1 - 9.2 6.3 9.9 2 8.4 1.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) YL1 PF05764.13 OEU09160.1 - 0.2 11.7 9.9 1.3 9.1 3.1 3.1 2 1 0 2 2 2 0 YL1 nuclear protein DUF1773 PF08593.10 OEU09160.1 - 2.7 9.1 5.0 2.7 9.1 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function SUIM_assoc PF16619.5 OEU09160.1 - 2.7 8.1 10.2 9.6 6.4 10.2 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 OEU09161.1 - 0.0028 18.6 4.1 0.0028 18.6 4.1 6.3 6 2 1 7 7 6 1 Domain of unknown function (DUF4834) DUF3295 PF11702.8 OEU09161.1 - 0.0045 16.4 9.2 0.0045 16.4 9.2 3.6 3 1 0 3 3 2 1 Protein of unknown function (DUF3295) Frizzled PF01534.17 OEU09161.1 - 0.0057 15.7 0.1 0.0099 15.0 0.1 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Cwf_Cwc_15 PF04889.12 OEU09161.1 - 0.0096 15.7 4.8 0.0096 15.7 4.8 5.7 4 2 0 4 4 2 1 Cwf15/Cwc15 cell cycle control protein ABC_export PF16962.5 OEU09161.1 - 0.013 14.0 0.1 0.024 13.1 0.1 1.3 1 0 0 1 1 1 0 Putative ABC exporter Mlo PF03094.15 OEU09161.1 - 0.026 12.9 0.1 0.064 11.6 0.1 1.6 1 0 0 1 1 1 0 Mlo family Ac76 PF05814.11 OEU09161.1 - 0.034 14.1 3.4 0.081 12.9 3.4 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) GAPT PF11770.8 OEU09161.1 - 0.077 12.9 0.1 0.077 12.9 0.1 3.4 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) V_ATPase_I PF01496.19 OEU09161.1 - 0.1 10.5 23.8 0.083 10.8 1.4 3.3 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Shisa PF13908.6 OEU09161.1 - 0.45 10.7 3.7 2.8 8.2 0.1 3.6 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OEU09161.1 - 0.57 11.1 8.7 0.11 13.3 2.5 3.2 2 2 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NFACT-R_1 PF05670.13 OEU09162.1 - 3.3e-07 30.9 0.0 9.5e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 NFACT protein RNA binding domain DUF4690 PF15756.5 OEU09162.1 - 0.19 12.3 0.1 2.6 8.7 0.0 2.8 3 1 0 3 3 3 0 Small Novel Rich in Cartilage zf-C4H2 PF10146.9 OEU09162.1 - 0.82 9.9 9.3 2.4 8.4 9.2 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein P53_TAD PF08563.11 OEU09163.1 - 0.055 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 P53 transactivation motif Pkinase_Tyr PF07714.17 OEU09164.1 - 3.5e-52 177.3 0.0 7.6e-52 176.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU09164.1 - 1.4e-43 149.1 0.0 3.3e-43 148.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OEU09164.1 - 0.0023 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU09164.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUIM_assoc PF16619.5 OEU09165.1 - 0.016 15.3 16.7 0.06 13.4 4.9 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 QIL1 PF15884.5 OEU09165.1 - 0.026 15.1 1.1 0.081 13.5 0.2 2.3 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 DUF3947 PF13135.6 OEU09165.1 - 3.2 8.0 9.2 0.52 10.5 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Abhydrolase_2 PF02230.16 OEU09166.1 - 9.1e-36 123.7 0.0 3e-35 122.0 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OEU09166.1 - 0.00019 21.2 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 OEU09166.1 - 0.00025 20.9 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OEU09166.1 - 0.00036 21.2 0.0 0.00049 20.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 OEU09166.1 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 OEU09166.1 - 0.011 15.0 0.0 0.27 10.5 0.0 2.5 2 1 1 3 3 3 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 OEU09166.1 - 0.038 13.5 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3915 PF13054.6 OEU09166.1 - 0.073 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TMEM154 PF15102.6 OEU09167.1 - 0.035 14.0 0.5 0.042 13.8 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 OEU09167.1 - 0.042 14.1 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF5305 PF17231.2 OEU09167.1 - 0.043 13.2 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Gemini_mov PF01708.16 OEU09167.1 - 0.049 13.4 0.2 0.058 13.2 0.2 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein TMEM51 PF15345.6 OEU09167.1 - 0.055 13.3 1.4 0.072 12.9 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 BatD PF13584.6 OEU09167.1 - 0.059 12.2 0.1 0.068 12.0 0.1 1.0 1 0 0 1 1 1 0 Oxygen tolerance EVC2_like PF12297.8 OEU09167.1 - 0.062 12.0 0.1 0.067 11.9 0.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Glycoprotein PF03409.15 OEU09167.1 - 0.086 11.7 2.1 0.11 11.4 2.1 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein Amnionless PF14828.6 OEU09167.1 - 0.093 11.5 0.0 0.093 11.5 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF3446 PF11928.8 OEU09167.1 - 0.12 12.7 14.3 0.17 12.2 14.3 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain FtsX PF02687.21 OEU09167.1 - 1.1 9.8 7.9 1.6 9.3 7.9 1.2 1 0 0 1 1 1 0 FtsX-like permease family KASH PF10541.9 OEU09167.1 - 1.1 9.6 8.2 1.7 9.0 8.2 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain Cortexin PF11057.8 OEU09167.1 - 1.2 9.0 6.2 1.6 8.6 6.2 1.4 1 1 0 1 1 1 0 Cortexin of kidney SET PF00856.28 OEU09168.1 - 1.2e-15 58.4 0.1 1.2e-15 58.4 0.1 3.4 2 1 0 2 2 2 1 SET domain MFS_1 PF07690.16 OEU09170.1 - 3.6e-15 55.7 41.0 5.2e-14 51.9 12.2 4.0 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF2182 PF09948.9 OEU09170.1 - 0.009 15.9 0.1 0.35 10.7 0.0 2.6 2 0 0 2 2 2 1 Predicted metal-binding integral membrane protein (DUF2182) zf-MYND PF01753.18 OEU09172.1 - 3e-07 30.4 15.9 6.2e-07 29.4 15.9 1.6 1 0 0 1 1 1 1 MYND finger RskA PF10099.9 OEU09172.1 - 0.0098 16.2 3.2 0.013 15.8 3.2 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Glyco_hydro_9 PF00759.19 OEU09172.1 - 6.3 6.1 6.6 9.1 5.6 6.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 FSA_C PF10479.9 OEU09173.1 - 7.5 4.6 7.2 7.6 4.5 7.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SPC22 PF04573.12 OEU09174.1 - 3.1e-49 166.8 0.5 3.4e-49 166.6 0.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PRKCSH_1 PF13015.6 OEU09175.1 - 9.6e-25 87.1 1.3 1.3e-24 86.6 1.3 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OEU09175.1 - 6.2e-08 33.5 0.8 6.2e-08 33.5 0.8 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4834 PF16118.5 OEU09176.1 - 0.011 16.7 2.2 0.011 16.7 2.2 5.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) MvaI_BcnI PF15515.6 OEU09177.1 - 0.0044 16.9 1.4 0.0056 16.5 1.4 1.3 1 0 0 1 1 1 1 MvaI/BcnI restriction endonuclease family CbiC PF02570.15 OEU09179.1 - 0.02 14.6 0.8 0.16 11.6 0.5 2.1 2 0 0 2 2 2 0 Precorrin-8X methylmutase Fasciclin PF02469.22 OEU09180.1 - 7.8e-10 39.1 0.0 7.8e-10 39.1 0.0 2.6 2 1 0 2 2 2 1 Fasciclin domain V-set PF07686.17 OEU09180.1 - 0.0037 17.4 6.7 6.3 7.0 0.1 4.6 1 1 3 4 4 4 3 Immunoglobulin V-set domain CNV-Replicase_N PF16688.5 OEU09180.1 - 0.11 12.8 0.2 0.29 11.5 0.2 1.6 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 FAD_binding_2 PF00890.24 OEU09181.1 - 2.1e-120 402.6 3.0 2.9e-120 402.1 3.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OEU09181.1 - 4.1e-40 136.7 0.1 6.3e-40 136.1 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OEU09181.1 - 5.9e-06 25.7 0.5 0.0087 15.3 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU09181.1 - 0.00014 21.2 0.1 0.016 14.4 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OEU09181.1 - 0.0019 17.5 1.2 0.0027 17.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OEU09181.1 - 0.0035 16.5 2.4 0.1 11.7 1.6 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 OEU09181.1 - 0.03 13.9 0.5 0.094 12.3 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OEU09181.1 - 0.13 11.0 0.6 0.85 8.3 0.6 2.2 3 0 0 3 3 3 0 HI0933-like protein DUF2525 PF10733.9 OEU09182.1 - 0.014 15.7 0.5 0.051 13.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) PT PF04886.12 OEU09183.1 - 1.4e-09 37.4 59.7 7e-08 31.9 20.8 6.3 2 2 3 5 5 5 4 PT repeat peroxidase PF00141.23 OEU09184.1 - 5.8e-69 232.3 0.0 1.9e-42 145.6 0.0 2.4 2 0 0 2 2 2 2 Peroxidase LRR_8 PF13855.6 OEU09185.1 - 0.019 14.7 0.9 0.019 14.7 0.9 2.0 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 OEU09185.1 - 0.05 14.1 5.2 0.25 11.8 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) OAD_gamma PF04277.13 OEU09185.1 - 1.8 9.2 14.8 0.47 11.1 4.3 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1754 PF08555.10 OEU09185.1 - 2.1 9.2 29.8 1.8 9.4 9.4 3.7 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Semialdhyde_dh PF01118.24 OEU09185.1 - 2.5 8.5 5.4 0.49 10.9 0.9 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L6e PF01159.19 OEU09185.1 - 3.9 8.0 16.9 1.7 9.2 7.2 2.8 2 0 0 2 2 2 0 Ribosomal protein L6e SBBP PF06739.11 OEU09186.1 - 1.1e-05 25.3 6.3 0.99 9.5 0.0 5.6 5 2 0 5 5 5 3 Beta-propeller repeat Reg_prop PF07494.11 OEU09186.1 - 1.5e-05 24.6 1.5 4.3 7.9 0.1 5.0 5 0 0 5 5 5 2 Two component regulator propeller Hyphal_reg_CWP PF11765.8 OEU09186.1 - 0.0075 15.2 2.7 0.075 12.0 0.5 2.7 3 0 0 3 3 3 1 Hyphally regulated cell wall protein N-terminal DUF3899 PF13038.6 OEU09187.1 - 0.07 13.6 0.3 2.1 8.9 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) CBAH PF02275.18 OEU09189.1 - 2e-37 129.6 0.1 1.7e-32 113.3 0.0 3.1 3 0 0 3 3 3 3 Linear amide C-N hydrolases, choloylglycine hydrolase family peroxidase PF00141.23 OEU09190.1 - 1.8e-38 132.5 0.0 2.4e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 OEU09191.1 - 2.4e-38 132.1 0.0 3.5e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase CMS1 PF14617.6 OEU09191.1 - 0.14 11.5 0.6 0.24 10.7 0.6 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PK PF00224.21 OEU09192.1 - 1.4e-100 336.6 0.0 1.8e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OEU09192.1 - 5.3e-30 104.1 0.1 1.8e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain DUF3652 PF12372.8 OEU09192.1 - 0.031 14.2 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 Huntingtin protein region HpcH_HpaI PF03328.14 OEU09192.1 - 0.077 12.1 0.0 1.4 8.0 0.0 2.6 3 1 0 3 3 3 0 HpcH/HpaI aldolase/citrate lyase family Sel_put PF04328.13 OEU09192.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative CA_like PF10563.9 OEU09193.1 - 8.4e-60 201.8 1.1 1.3e-59 201.1 1.1 1.3 1 0 0 1 1 1 1 Putative carbonic anhydrase Fasciclin PF02469.22 OEU09193.1 - 1.9e-05 24.9 0.0 6.2e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Fasciclin domain Cellulase PF00150.18 OEU09194.1 - 2.7e-10 40.2 1.6 5e-10 39.3 1.6 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNARE_assoc PF09335.11 OEU09194.1 - 0.0061 17.0 0.2 0.011 16.2 0.2 1.3 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF3169 PF11368.8 OEU09194.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) UPF0242 PF06785.11 OEU09194.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAD_binding_3 PF01494.19 OEU09195.1 - 5.2e-06 25.9 0.1 1e-05 24.9 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Cep57_CLD_2 PF14197.6 OEU09196.1 - 0.0023 18.0 1.4 0.0047 17.0 1.4 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Spc24 PF08286.11 OEU09196.1 - 0.14 12.4 3.1 0.87 9.9 1.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Mito_carr PF00153.27 OEU09198.1 - 4e-21 74.7 2.4 1.1e-09 38.1 0.1 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein DUF4202 PF13875.6 OEU09199.1 - 0.099 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) TALPID3 PF15324.6 OEU09200.1 - 0.22 9.1 1.4 0.31 8.7 1.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zf-CHY PF05495.12 OEU09201.1 - 0.1 13.1 26.0 0.057 13.9 12.8 2.2 1 1 1 2 2 2 0 CHY zinc finger Helicase_C PF00271.31 OEU09202.1 - 3.9e-10 40.0 0.0 5.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MutS_V PF00488.21 OEU09203.1 - 1e-36 126.7 0.0 3.4e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_I PF01624.20 OEU09203.1 - 1.7e-05 25.0 0.1 0.0012 19.1 0.1 2.5 1 1 0 1 1 1 1 MutS domain I GIY-YIG PF01541.24 OEU09203.1 - 0.0044 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA PF00004.29 OEU09203.1 - 0.036 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU09203.1 - 0.08 12.5 0.1 0.93 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OEU09203.1 - 0.17 11.7 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU09203.1 - 9.2 6.7 9.6 13 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain Peptidase_C10 PF01640.17 OEU09207.1 - 0.089 13.1 2.1 0.31 11.3 1.3 2.0 2 0 0 2 2 2 0 Peptidase C10 family Dynein_IC2 PF11540.8 OEU09208.1 - 0.049 13.6 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 LRR_6 PF13516.6 OEU09208.1 - 0.68 10.1 6.0 1.1 9.5 0.2 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Sulfotransfer_1 PF00685.27 OEU09209.1 - 0.004 16.7 0.7 0.65 9.4 0.3 3.1 2 1 0 2 2 2 1 Sulfotransferase domain ETRAMP PF09716.10 OEU09209.1 - 0.0087 16.1 1.8 0.023 14.7 1.8 1.7 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) BT1 PF03092.16 OEU09209.1 - 0.0087 14.3 0.0 0.013 13.8 0.0 1.2 1 0 0 1 1 1 1 BT1 family MacB_PCD PF12704.7 OEU09209.1 - 0.13 12.6 0.3 0.25 11.7 0.3 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain SID-1_RNA_chan PF13965.6 OEU09209.1 - 0.32 9.3 2.0 0.56 8.6 2.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4050 PF13259.6 OEU09209.1 - 0.44 10.9 6.5 3.6 7.9 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) PRIMA1 PF16101.5 OEU09209.1 - 0.76 9.8 7.9 0.93 9.5 6.1 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4366 PF14283.6 OEU09209.1 - 0.92 9.5 5.1 0.73 9.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) CAP_N PF01213.19 OEU09209.1 - 9.3 5.6 12.5 0.83 9.1 4.0 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRP1_N PF06424.12 OEU09214.1 - 0.0098 16.3 0.6 0.017 15.6 0.6 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal DUF2866 PF11065.8 OEU09214.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Methyltransf_21 PF05050.12 OEU09216.1 - 2.4e-08 34.2 0.1 9.6e-08 32.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain 2OG-FeII_Oxy_2 PF13532.6 OEU09217.1 - 6.9e-14 52.5 0.0 1e-13 51.9 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2_assoc PF16606.5 OEU09218.1 - 0.071 13.3 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers AKAP2_C PF15304.6 OEU09219.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus AWS PF17907.1 OEU09219.1 - 0.1 12.7 1.6 0.29 11.2 0.7 2.1 2 0 0 2 2 2 0 AWS domain CMAS PF02353.20 OEU09220.1 - 2.3e-30 105.9 0.3 3e-30 105.5 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OEU09220.1 - 4.4e-12 46.6 0.0 6.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU09220.1 - 2.7e-11 43.5 0.0 4.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU09220.1 - 1.5e-10 41.7 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU09220.1 - 2.9e-10 40.6 0.0 5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU09220.1 - 7.2e-09 35.7 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU09220.1 - 5.6e-07 29.3 0.0 9.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OEU09220.1 - 2.9e-06 26.9 0.0 7.8e-06 25.5 0.0 1.7 1 1 1 2 2 2 1 Putative methyltransferase DREV PF05219.12 OEU09220.1 - 0.013 14.6 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 OEU09220.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 OEU09220.1 - 0.031 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 OEU09220.1 - 0.062 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PSII_Pbs27 PF13326.6 OEU09221.1 - 1.2e-32 113.2 1.2 3.1e-32 111.8 1.2 1.6 1 1 0 1 1 1 1 Photosystem II Pbs27 TAT_signal PF10518.9 OEU09221.1 - 9.9e-06 25.2 2.3 9.9e-06 25.2 2.3 1.9 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 OEU09221.1 - 2.7e-05 23.4 1.9 2.7e-05 23.4 1.9 2.1 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF1800 PF08811.11 OEU09222.1 - 2.5e-50 171.8 0.0 9.7e-31 107.2 0.0 3.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1800) DUF1501 PF07394.12 OEU09222.1 - 3.7e-33 115.1 0.1 6.9e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) zf-CW PF07496.15 OEU09222.1 - 5.6e-10 39.1 3.6 1.7e-09 37.6 3.6 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger DUF401 PF04165.12 OEU09223.1 - 0.022 14.1 0.2 0.031 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) LapA_dom PF06305.11 OEU09223.1 - 1.2 9.1 4.4 7.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PLAC8 PF04749.17 OEU09224.1 - 0.0018 19.3 7.1 0.12 13.4 0.6 2.2 2 0 0 2 2 2 2 PLAC8 family SLAC1 PF03595.17 OEU09224.1 - 0.05 12.9 0.5 0.071 12.4 0.5 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF1218 PF06749.12 OEU09224.1 - 0.077 13.5 0.3 0.077 13.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Orf78 PF06024.12 OEU09224.1 - 0.62 10.4 3.1 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 OEU09224.1 - 2.2 8.2 11.6 0.15 11.9 2.3 2.4 2 0 0 2 2 2 0 TMEM154 protein family DUF4191 PF13829.6 OEU09224.1 - 3 7.1 4.2 4.4 6.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PAP_fibrillin PF04755.12 OEU09225.1 - 2.8e-08 34.0 0.1 7.3e-07 29.3 0.1 2.9 1 1 0 1 1 1 1 PAP_fibrillin PfUIS3 PF11567.8 OEU09226.1 - 0.047 14.0 0.4 0.076 13.4 0.4 1.4 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein DUF1697 PF08002.11 OEU09227.1 - 3.9e-21 75.9 0.1 1.3e-20 74.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1697) AbiGi PF10899.8 OEU09227.1 - 0.0099 15.8 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative abortive phage resistance protein AbiGi, antitoxin DNA_pol_A_exo1 PF01612.20 OEU09228.1 - 4.5e-11 42.8 0.0 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Apc13p PF05839.11 OEU09228.1 - 0.35 11.1 3.4 4.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Apc13p protein XRCC4 PF06632.12 OEU09229.1 - 0.063 12.1 0.6 0.067 12.0 0.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Metallophos PF00149.28 OEU09230.1 - 1.5e-17 64.8 0.4 1.5e-17 64.8 0.4 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OEU09230.1 - 5.5e-09 36.8 1.5 6.7e-09 36.5 0.2 1.8 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Phage_endo_I PF05367.11 OEU09230.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Phage endonuclease I Metallophos_2 PF12850.7 OEU09230.1 - 0.03 14.5 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GATase_3 PF07685.14 OEU09231.1 - 5.8e-19 68.5 0.0 8.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 OEU09231.1 - 2.1e-13 50.5 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 OEU09231.1 - 4e-10 39.9 0.0 6.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain CTP_synth_N PF06418.14 OEU09231.1 - 0.037 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus Glyco_trans_4_4 PF13579.6 OEU09231.1 - 0.096 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain SRP54 PF00448.22 OEU09231.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.14 OEU09231.1 - 0.13 12.1 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_5 PF13857.6 OEU09232.1 - 4.5e-05 23.6 0.0 0.0033 17.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU09232.1 - 0.0003 21.3 0.0 0.024 15.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU09232.1 - 0.00065 20.0 0.1 0.17 12.6 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OEU09232.1 - 0.017 15.7 0.0 0.52 10.9 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SUIM_assoc PF16619.5 OEU09232.1 - 0.068 13.3 4.6 1.1 9.4 0.4 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NP1-WLL PF11733.8 OEU09236.1 - 0.0088 15.8 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 1 Non-capsid protein NP1 RF-1 PF00472.20 OEU09237.1 - 1e-21 77.1 7.0 1e-21 77.1 7.0 1.9 1 1 1 2 2 2 1 RF-1 domain Dis3l2_C_term PF17877.1 OEU09237.1 - 0.015 15.6 2.2 0.015 15.6 2.2 2.0 1 1 1 2 2 2 0 DIS3-like exonuclease 2 C terminal LicD PF04991.13 OEU09237.1 - 0.15 12.2 6.8 0.17 12.0 6.8 1.0 1 0 0 1 1 1 0 LicD family PBP_sp32 PF07222.12 OEU09237.1 - 0.63 9.4 9.6 0.65 9.4 9.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 STAC2_u1 PF16664.5 OEU09237.1 - 1 9.8 6.7 1.7 9.1 6.7 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF1157 PF06636.11 OEU09238.1 - 0.025 13.4 0.3 0.039 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) Rhamno_transf PF11316.8 OEU09239.1 - 0.0031 16.9 0.1 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 Putative rhamnosyl transferase Oxidored_nitro PF00148.19 OEU09240.1 - 0.028 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Dimerisation2 PF16864.5 OEU09240.1 - 0.037 14.0 0.0 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain Chloroa_b-bind PF00504.21 OEU09242.1 - 9e-30 104.3 0.0 1.2e-29 103.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NAD_binding_11 PF14833.6 OEU09243.1 - 6.5e-25 87.7 0.5 1e-24 87.1 0.5 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OEU09243.1 - 7.1e-23 81.5 0.1 1.6e-17 64.2 0.0 2.6 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase GoLoco PF02188.17 OEU09246.1 - 0.035 13.6 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 GoLoco motif zf-UBP PF02148.19 OEU09246.1 - 0.16 12.4 3.9 0.23 11.8 1.2 2.7 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-HIT PF04438.16 OEU09246.1 - 0.16 11.9 6.9 0.35 10.8 6.9 1.6 1 0 0 1 1 1 0 HIT zinc finger DUF2070 PF09843.9 OEU09247.1 - 0.73 8.0 16.0 0.042 12.2 11.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) zf-CCCH_3 PF15663.5 OEU09248.1 - 0.032 14.4 0.1 0.26 11.5 0.0 2.2 2 1 0 2 2 2 0 Zinc-finger containing family Peptidase_M16_M PF16187.5 OEU09249.1 - 9e-55 185.9 0.0 1.8e-54 185.0 0.0 1.5 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OEU09249.1 - 5.1e-35 120.6 0.1 2.8e-34 118.2 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU09249.1 - 4.9e-22 78.8 0.0 1.5e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Aldo_ket_red PF00248.21 OEU09250.1 - 9.6e-39 133.3 0.7 2.3e-38 132.1 0.7 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro81C PF17652.1 OEU09251.1 - 7.9e-16 58.2 0.1 9.5e-16 58.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain DUF1995 PF09353.10 OEU09254.1 - 1.9e-10 41.1 0.0 2.4e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Lipase_3 PF01764.25 OEU09255.1 - 1.4e-10 41.2 0.0 5.5e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) DUF2974 PF11187.8 OEU09255.1 - 0.0013 18.4 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) WD40 PF00400.32 OEU09256.1 - 3.7e-16 59.2 15.3 0.0021 18.9 0.1 5.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU09256.1 - 8.5e-05 22.8 0.0 11 6.3 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1373 PF07117.11 OEU09256.1 - 0.1 12.6 4.1 0.15 12.0 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1373) Ge1_WD40 PF16529.5 OEU09256.1 - 0.11 11.4 0.1 1.3 7.9 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Put_Phosphatase PF06888.12 OEU09257.1 - 0.017 14.5 1.5 0.17 11.2 0.0 3.0 3 1 1 4 4 4 0 Putative Phosphatase Hydrolase PF00702.26 OEU09257.1 - 0.063 13.6 0.0 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OEU09257.1 - 0.068 13.2 2.6 1.4 9.0 0.0 3.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Na_trans_cytopl PF11933.8 OEU09257.1 - 0.11 12.3 1.1 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Cytoplasmic domain of voltage-gated Na+ ion channel Phostensin_N PF13916.6 OEU09257.1 - 0.26 11.7 2.3 5.9 7.3 0.4 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4834 PF16118.5 OEU09257.1 - 0.28 12.2 2.7 21 6.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 OEU09257.1 - 0.58 10.3 12.8 1.1 9.4 0.4 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FSH1 PF03959.13 OEU09258.1 - 4.2e-10 39.6 0.1 1.4e-09 38.0 0.1 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Coilin_N PF15862.5 OEU09258.1 - 0.34 10.7 7.5 0.045 13.6 2.2 2.3 2 0 0 2 2 2 0 Coilin N-terminus PHD_like PF12910.7 OEU09259.1 - 0.11 12.5 0.4 0.14 12.2 0.4 1.2 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Baculo_F PF12259.8 OEU09259.1 - 0.17 10.4 0.3 0.2 10.1 0.3 1.0 1 0 0 1 1 1 0 Baculovirus F protein RETICULATA-like PF11891.8 OEU09260.1 - 2e-35 122.2 0.0 3.4e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Protein RETICULATA-related FDF PF09532.10 OEU09260.1 - 0.022 15.6 3.0 0.045 14.6 3.0 1.5 1 0 0 1 1 1 0 FDF domain Tim17 PF02466.19 OEU09260.1 - 0.067 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ELO PF01151.18 OEU09261.1 - 6.7e-49 166.7 26.2 1.2e-48 165.9 26.2 1.3 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1211 PF06736.11 OEU09261.1 - 3 8.4 11.0 8.1 7.0 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) BofC_C PF08955.10 OEU09264.1 - 0.09 12.8 0.0 8.3 6.5 0.0 2.9 2 1 1 3 3 3 0 BofC C-terminal domain zf-MIZ PF02891.20 OEU09265.1 - 1.3e-12 47.3 0.4 2.4e-12 46.4 0.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OEU09265.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Serglycin PF04360.12 OEU09265.1 - 0.016 15.2 2.2 0.11 12.4 2.0 2.5 2 0 0 2 2 2 0 Serglycin XhlA PF10779.9 OEU09266.1 - 3.7 7.8 8.8 34 4.7 0.3 3.6 2 0 0 2 2 2 0 Haemolysin XhlA Pro_isomerase PF00160.21 OEU09268.1 - 3e-46 157.6 0.4 3.6e-46 157.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldo_ket_red PF00248.21 OEU09269.1 - 1.2e-19 70.7 0.0 2.2e-17 63.2 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family zf-trcl PF13451.6 OEU09269.1 - 0.46 10.4 2.0 18 5.3 0.0 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain MatE PF01554.18 OEU09270.1 - 7.8e-12 45.1 29.2 1.5e-11 44.2 6.0 3.5 4 0 0 4 4 4 3 MatE Polysacc_synt_C PF14667.6 OEU09270.1 - 2.2e-08 34.3 1.2 2.2e-08 34.3 1.2 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 OEU09270.1 - 2.6e-05 23.0 0.9 2.6e-05 23.0 0.9 2.1 1 1 1 2 2 2 1 Lipid II flippase MurJ Dicty_REP PF05086.12 OEU09270.1 - 0.15 10.0 6.1 0.23 9.4 6.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CSG2 PF16965.5 OEU09272.1 - 0.15 10.9 1.5 0.22 10.4 1.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator OSTbeta PF15048.6 OEU09272.1 - 0.18 12.0 0.9 0.41 10.8 0.9 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein HATPase_c PF02518.26 OEU09274.1 - 1.9e-21 76.7 0.0 7.4e-21 74.8 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OEU09274.1 - 1.3e-16 60.8 0.2 3.2e-16 59.5 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OEU09274.1 - 1e-08 35.1 0.3 3.3e-08 33.4 0.3 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain YiaAB PF05360.14 OEU09274.1 - 0.14 12.4 0.3 2.4 8.5 0.0 2.9 3 0 0 3 3 3 0 yiaA/B two helix domain MRP-S23 PF10484.9 OEU09275.1 - 0.18 12.1 0.2 1.9 8.8 0.2 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 DUF2408 PF10303.9 OEU09277.1 - 1.4 9.4 9.7 2.6 8.6 9.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Ank_3 PF13606.6 OEU09278.1 - 0.00016 21.8 1.5 2.7 8.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OEU09278.1 - 0.00068 20.1 0.0 0.0024 18.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU09278.1 - 0.001 19.3 3.4 0.097 13.0 0.3 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Phage_int_SAM_1 PF02899.17 OEU09278.1 - 0.21 11.9 3.0 0.39 11.0 1.0 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain WDCP PF15390.6 OEU09278.1 - 0.24 9.7 12.3 0.43 8.9 12.3 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF1664 PF07889.12 OEU09278.1 - 1.6 8.7 15.2 0.85 9.7 4.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ImpA_N PF06812.12 OEU09278.1 - 2.2 8.4 7.9 12 6.1 1.2 2.5 1 1 0 2 2 2 0 ImpA, N-terminal, type VI secretion system YtxH PF12732.7 OEU09278.1 - 3.2 8.3 7.8 0.94 10.1 2.2 2.6 1 1 1 2 2 2 0 YtxH-like protein Laminin_II PF06009.12 OEU09278.1 - 3.8 7.5 20.9 0.1 12.6 6.1 2.8 2 1 1 3 3 3 0 Laminin Domain II DUF4407 PF14362.6 OEU09278.1 - 3.9 6.7 14.8 6.8 5.9 14.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 OEU09278.1 - 7.3 5.8 11.1 12 5.1 11.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4404 PF14357.6 OEU09278.1 - 7.5 7.3 17.6 0.18 12.4 2.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Pkinase PF00069.25 OEU09279.1 - 2.9e-51 174.3 0.0 1.3e-50 172.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09279.1 - 4.2e-28 98.3 0.1 5.3e-27 94.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU09279.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU09279.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OEU09279.1 - 0.0018 18.0 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 OEU09279.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OEU09279.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OEU09279.1 - 0.03 13.3 0.1 0.036 13.0 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain TAFII28 PF04719.14 OEU09279.1 - 0.077 13.1 0.1 22 5.2 0.0 3.3 3 1 0 3 3 3 0 hTAFII28-like protein conserved region APH PF01636.23 OEU09279.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DRTGG PF07085.12 OEU09279.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain DUF4336 PF14234.6 OEU09280.1 - 1.3e-51 175.7 0.1 2.6e-41 141.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Melibiase PF02065.18 OEU09280.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Melibiase NAD_binding_8 PF13450.6 OEU09281.1 - 1.6e-13 50.7 0.6 4e-13 49.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU09281.1 - 2.4e-12 46.9 0.1 7.9e-07 28.7 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OEU09281.1 - 5.7e-06 25.8 0.1 0.0001 21.6 0.4 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU09281.1 - 2.8e-05 23.9 3.7 5e-05 23.1 3.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OEU09281.1 - 0.00018 21.0 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU09281.1 - 0.00019 20.7 2.7 0.00028 20.1 2.7 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OEU09281.1 - 0.00043 19.7 1.0 0.0007 18.9 1.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OEU09281.1 - 0.00092 19.7 1.6 0.0085 16.6 0.9 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 OEU09281.1 - 0.0024 17.0 0.1 0.0037 16.4 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III Thi4 PF01946.17 OEU09281.1 - 0.0065 15.7 0.5 0.014 14.7 0.5 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OEU09281.1 - 0.0098 14.6 0.9 0.014 14.1 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 OEU09281.1 - 0.024 14.5 0.3 0.047 13.6 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OEU09281.1 - 0.042 13.1 0.5 0.07 12.4 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OEU09281.1 - 0.047 12.8 0.9 0.084 11.9 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OEU09281.1 - 0.062 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.19 OEU09281.1 - 0.089 11.2 0.1 0.15 10.4 0.1 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 OEU09281.1 - 0.15 12.0 0.9 0.72 9.8 0.3 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ank_5 PF13857.6 OEU09282.1 - 0.0017 18.7 0.0 0.0062 16.8 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) CENP-B_dimeris PF09026.10 OEU09282.1 - 0.022 15.1 2.4 0.022 15.1 2.4 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain GST_C PF00043.25 OEU09283.1 - 2.3e-06 27.8 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU09283.1 - 1e-05 25.8 0.0 1.8e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU09283.1 - 0.00052 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU09283.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OEU09283.1 - 0.0022 18.7 0.0 0.0034 18.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 OEU09283.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 OEU09283.1 - 0.07 13.4 0.0 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein GlcNAc PF11397.8 OEU09284.1 - 4.1e-35 121.9 0.0 7.9e-35 120.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) SET PF00856.28 OEU09285.1 - 6.4e-11 42.9 0.0 1.4e-10 41.8 0.0 1.6 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 OEU09285.1 - 0.0022 18.3 2.6 0.0045 17.2 2.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU09285.1 - 0.0054 16.6 0.3 0.065 13.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU09285.1 - 0.037 14.2 4.0 0.076 13.3 1.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF295 PF03478.18 OEU09285.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) TPR_2 PF07719.17 OEU09285.1 - 0.11 12.7 4.9 0.22 11.7 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU09285.1 - 0.12 12.2 4.0 0.74 9.7 1.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU09285.1 - 0.14 12.3 0.5 1.8 8.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU09285.1 - 0.27 11.9 1.6 2.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF760 PF05542.11 OEU09286.1 - 8e-39 131.9 0.5 1.3e-18 67.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Tmemb_9 PF05434.11 OEU09287.1 - 0.45 10.4 3.4 18 5.2 0.0 2.8 3 0 0 3 3 3 0 TMEM9 DUF2615 PF11027.8 OEU09287.1 - 0.67 10.1 0.0 0.67 10.1 0.0 2.7 2 1 1 4 4 4 0 Protein of unknown function (DUF2615) Neur_chan_memb PF02932.16 OEU09287.1 - 0.83 9.7 5.5 1.4 8.9 5.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.6 OEU09287.1 - 1.1 10.1 7.5 14 6.6 7.5 2.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SpoIIIAH PF12685.7 OEU09287.1 - 2.2 8.0 9.1 0.28 11.0 3.9 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein Miga PF10265.9 OEU09287.1 - 6 5.7 16.9 8.9 5.2 16.9 1.2 1 0 0 1 1 1 0 Mitoguardin GREB1 PF15782.5 OEU09287.1 - 7.2 3.6 9.9 6.4 3.7 9.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP-binding PF00550.25 OEU09289.1 - 3.7e-12 46.4 0.3 5.3e-12 45.9 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OEU09289.1 - 0.00032 20.9 0.6 0.00043 20.4 0.6 1.3 1 0 0 1 1 1 1 Acyl-carrier Aminotran_3 PF00202.21 OEU09290.1 - 4.6e-119 397.7 0.0 5.2e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OEU09290.1 - 0.00053 19.3 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OEU09290.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase COPIIcoated_ERV PF07970.12 OEU09291.1 - 3.1e-66 223.4 0.3 4.9e-66 222.7 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OEU09291.1 - 3.8e-21 75.2 0.0 7.2e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FBPase PF00316.20 OEU09292.1 - 1.6e-35 122.3 0.1 2.5e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Mu-like_gpT PF10124.9 OEU09293.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT FBPase PF00316.20 OEU09294.1 - 1.1e-19 70.6 0.1 1.7e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OEU09294.1 - 0.0035 16.9 0.8 0.006 16.1 0.8 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Bestrophin PF01062.21 OEU09295.1 - 4.1e-24 85.5 0.6 6.6e-24 84.8 0.6 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SelK_SelG PF10961.8 OEU09296.1 - 0.85 10.3 5.6 11 6.7 0.1 3.1 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Exo_endo_phos PF03372.23 OEU09297.1 - 0.021 14.3 0.0 0.099 12.1 0.0 2.0 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DZR PF12773.7 OEU09297.1 - 0.21 11.7 1.4 0.51 10.4 1.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon PNPase_C PF12111.8 OEU09297.1 - 0.28 10.7 0.8 0.57 9.6 0.8 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal UPF0149 PF03695.13 OEU09297.1 - 1.4 9.2 5.2 0.29 11.4 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Clr2 PF10383.9 OEU09297.1 - 6 7.6 8.2 0.46 11.2 1.6 2.5 3 0 0 3 3 3 0 Transcription-silencing protein Clr2 Ig_5 PF16681.5 OEU09298.1 - 0.054 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TPR_12 PF13424.6 OEU09299.1 - 1.6e-34 118.0 0.7 8e-15 54.9 0.0 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OEU09299.1 - 8.1e-32 108.2 0.7 2.3e-09 36.8 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU09299.1 - 2.3e-20 71.5 0.8 7.7e-05 22.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU09299.1 - 2.2e-16 58.6 2.8 0.00053 19.9 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU09299.1 - 6.3e-13 47.8 1.8 0.035 14.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU09299.1 - 2.6e-10 39.6 1.2 4.5e-05 23.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU09299.1 - 1.6e-05 25.3 0.6 0.44 11.5 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU09299.1 - 2.6e-05 24.8 1.0 0.01 16.5 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU09299.1 - 5.7e-05 22.6 0.3 0.00027 20.4 0.2 1.8 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OEU09299.1 - 0.00084 19.8 0.3 0.25 11.9 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU09299.1 - 0.0013 18.9 0.0 0.55 10.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU09299.1 - 0.0066 17.0 0.2 1.1 10.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU09299.1 - 0.039 13.4 0.1 3 7.4 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR ANAPC3 PF12895.7 OEU09299.1 - 0.072 13.3 0.2 1.2 9.4 0.1 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OEU09299.1 - 0.13 12.4 0.0 6 7.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M16_C PF05193.21 OEU09301.1 - 9.8e-42 143.0 0.0 8.4e-22 78.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OEU09301.1 - 2.2e-15 56.9 0.2 2.1e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SOAR PF16533.5 OEU09301.1 - 0.03 14.3 2.2 6.5 6.8 0.1 2.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region Sdh_cyt PF01127.22 OEU09302.1 - 3.5e-16 59.3 0.1 5e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit COX6C PF02937.15 OEU09303.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc SLC35F PF06027.12 OEU09304.1 - 2e-07 30.8 1.9 2e-07 30.8 1.9 2.0 3 0 0 3 3 3 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 OEU09304.1 - 1.3e-05 24.5 2.2 2.3e-05 23.7 2.2 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 OEU09304.1 - 0.00048 19.4 0.1 0.00048 19.4 0.1 2.3 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport EamA PF00892.20 OEU09304.1 - 0.0013 18.9 0.4 0.0013 18.9 0.4 4.3 3 2 0 3 3 3 1 EamA-like transporter family Multi_Drug_Res PF00893.19 OEU09304.1 - 0.075 13.7 0.7 0.075 13.7 0.7 2.8 3 2 0 3 3 3 0 Small Multidrug Resistance protein R-HINP1I PF11463.8 OEU09306.1 - 0.0068 15.9 2.1 0.089 12.2 0.1 2.7 3 0 0 3 3 3 1 R.HinP1I restriction endonuclease RcbX PF02341.15 OEU09306.1 - 0.035 14.4 5.6 0.1 12.9 0.3 3.5 4 1 0 4 4 4 0 RbcX protein TetR_C_8 PF14278.6 OEU09306.1 - 0.47 10.6 3.5 2.7 8.2 0.1 3.2 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region PSK_trans_fac PF07704.11 OEU09306.1 - 1.1 10.1 5.4 1.3 9.8 0.1 2.8 2 0 0 2 2 2 0 Rv0623-like transcription factor DUF4611 PF15387.6 OEU09306.1 - 1.5 9.1 12.5 0.33 11.2 6.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WRNPLPNID PF15017.6 OEU09306.1 - 2.6 9.0 12.9 20 6.2 6.0 2.8 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Ion_trans_2 PF07885.16 OEU09307.1 - 2.6e-24 85.0 19.7 2.4e-13 49.8 4.8 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 OEU09307.1 - 1.7e-06 27.4 7.8 0.013 14.7 0.1 2.6 2 1 0 2 2 2 2 Ion transport protein Allene_ox_cyc PF06351.11 OEU09308.1 - 0.018 14.8 3.4 2.5 7.8 0.1 2.4 1 1 1 2 2 2 0 Allene oxide cyclase Ribosomal_L35Ae PF01247.18 OEU09308.1 - 0.034 14.3 0.5 13 6.0 0.0 3.2 2 1 1 3 3 3 0 Ribosomal protein L35Ae zf-C3HC4_3 PF13920.6 OEU09308.1 - 0.43 10.5 12.7 0.82 9.6 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GCR1_C PF12550.8 OEU09309.1 - 0.034 14.4 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 Transcriptional activator of glycolytic enzymes MHYT PF03707.16 OEU09312.1 - 0.0013 18.8 10.2 0.031 14.5 0.0 3.9 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat TctB PF07331.11 OEU09312.1 - 0.014 15.7 5.8 0.069 13.4 5.9 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cyt_c_ox_IV PF12270.8 OEU09312.1 - 0.31 11.2 6.5 0.46 10.6 0.0 3.4 3 1 0 3 3 3 0 Cytochrome c oxidase subunit IV DUF4229 PF14012.6 OEU09312.1 - 0.39 10.8 11.6 5.8 7.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) SieB PF14163.6 OEU09312.1 - 0.6 9.6 0.0 0.6 9.6 0.0 2.2 3 0 0 3 3 3 0 Super-infection exclusion protein B LSM PF01423.22 OEU09313.1 - 4.3e-18 64.8 0.0 5.2e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain PMC2NT PF08066.12 OEU09314.1 - 0.12 13.1 0.7 1.2 9.9 0.1 3.1 2 1 0 2 2 2 0 PMC2NT (NUC016) domain DUF948 PF06103.11 OEU09314.1 - 7.3 6.9 8.7 19 5.6 0.4 4.2 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4430 PF14478.6 OEU09315.1 - 0.16 12.5 0.9 0.34 11.5 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Chorion_2 PF03964.15 OEU09316.1 - 0.53 11.2 9.2 0.34 11.8 6.3 2.1 2 0 0 2 2 2 0 Chorion family 2 TspO_MBR PF03073.15 OEU09318.1 - 4e-26 91.7 7.3 4.9e-26 91.4 7.3 1.1 1 0 0 1 1 1 1 TspO/MBR family MCM PF00493.23 OEU09319.1 - 1.8e-95 318.3 0.0 3.1e-95 317.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OEU09319.1 - 2.3e-31 108.3 0.0 4.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OEU09319.1 - 2.6e-20 72.6 0.2 4.9e-20 71.8 0.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OEU09319.1 - 2.5e-07 30.3 0.4 1.4e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OEU09319.1 - 0.0026 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4611 PF15387.6 OEU09319.1 - 10 6.4 8.2 2.9 8.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Ribosomal_L15e PF00827.17 OEU09321.1 - 7.7e-91 303.0 10.0 8.9e-91 302.8 10.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hepatitis_core PF00906.20 OEU09321.1 - 0.091 12.3 0.2 0.091 12.3 0.2 1.5 2 0 0 2 2 2 0 Hepatitis core antigen Ribosomal_L28e PF01778.17 OEU09322.1 - 3.6e-25 88.9 2.6 4.4e-25 88.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Exo_endo_phos PF03372.23 OEU09323.1 - 1.6e-07 31.1 0.0 5e-06 26.2 0.0 2.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.29 OEU09324.1 - 2e-47 161.2 0.3 3.6e-47 160.4 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU09324.1 - 6.2e-31 107.0 0.0 1e-28 99.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU09324.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU09324.1 - 0.032 14.5 2.9 2.2 8.6 2.5 2.9 2 1 0 2 2 2 0 AAA domain Attacin_C PF03769.15 OEU09329.1 - 0.15 12.3 0.1 29 4.9 0.0 2.6 1 1 3 4 4 4 0 Attacin, C-terminal region MMU163 PF17119.5 OEU09330.1 - 1.4 8.1 4.6 2.2 7.4 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PD40 PF07676.12 OEU09331.1 - 0.0081 16.1 0.9 4.6 7.3 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 OEU09331.1 - 0.0088 16.9 6.4 0.036 15.0 0.6 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat DPPIV_N PF00930.21 OEU09331.1 - 0.32 9.7 2.6 11 4.6 0.1 3.4 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SAP PF02037.27 OEU09332.1 - 1.1e-10 41.0 1.4 2.6e-10 39.8 1.4 1.7 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 OEU09332.1 - 0.0047 16.5 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal SR-25 PF10500.9 OEU09332.1 - 0.81 9.3 31.0 0.11 12.0 0.7 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein HGTP_anticodon2 PF12745.7 OEU09332.1 - 0.9 9.0 10.9 2 7.9 1.0 2.3 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Band_3_cyto PF07565.13 OEU09332.1 - 1.3 8.8 7.4 2.2 8.0 0.1 2.5 2 1 1 3 3 3 0 Band 3 cytoplasmic domain SR-25 PF10500.9 OEU09333.1 - 0.004 16.8 4.6 0.004 16.8 4.6 2.4 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein Peroxin-3 PF04882.12 OEU09334.1 - 5.6 5.8 7.6 0.3 10.0 2.0 1.5 2 0 0 2 2 2 0 Peroxin-3 BTB_2 PF02214.22 OEU09335.1 - 1.2e-08 35.2 0.1 4.3e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 OEU09336.1 - 1e-64 218.4 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09336.1 - 1.3e-34 119.6 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OEU09336.1 - 1.7e-05 25.1 1.8 0.00015 22.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU09336.1 - 3e-05 23.6 2.7 0.0072 16.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OEU09336.1 - 3.5e-05 23.1 2.5 0.012 15.1 0.1 2.8 2 0 0 2 2 2 2 EF hand Kdo PF06293.14 OEU09336.1 - 4.5e-05 22.9 0.1 7.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU09336.1 - 0.00074 18.4 0.1 0.0013 17.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OEU09336.1 - 0.0014 18.0 0.0 0.011 15.1 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OEU09336.1 - 0.0064 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OEU09336.1 - 0.012 14.6 0.2 0.019 13.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain EF-hand_5 PF13202.6 OEU09336.1 - 0.012 15.1 3.8 0.35 10.4 0.2 2.7 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 OEU09336.1 - 0.041 13.7 1.4 1.2 9.0 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain pair Choline_kinase PF01633.20 OEU09336.1 - 0.054 13.1 0.5 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fasciclin PF02469.22 OEU09337.1 - 1.5e-06 28.4 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain hnRNP_Q_AcD PF18360.1 OEU09339.1 - 1.5e-28 98.5 0.0 1.8e-15 56.6 0.0 3.4 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain UreE_N PF02814.15 OEU09341.1 - 0.057 13.0 0.7 0.057 13.0 0.7 1.6 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain POM121 PF15229.6 OEU09342.1 - 0.034 13.8 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 POM121 family DUF5488 PF17590.2 OEU09342.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5488) PglZ PF08665.12 OEU09343.1 - 0.022 14.9 0.2 0.037 14.1 0.2 1.3 1 0 0 1 1 1 0 PglZ domain Y_Y_Y PF07495.13 OEU09344.1 - 3.2e-16 59.0 0.0 0.052 13.5 0.0 4.5 4 0 0 4 4 4 4 Y_Y_Y domain Adipokin_hormo PF06377.11 OEU09344.1 - 3e-07 30.7 0.0 13 6.2 0.0 4.5 4 0 0 4 4 4 4 Adipokinetic hormone PQQ PF01011.21 OEU09344.1 - 0.018 15.0 10.8 32 4.7 0.1 4.7 4 0 0 4 4 4 0 PQQ enzyme repeat PPC PF04151.15 OEU09344.1 - 0.051 14.7 14.4 26 6.0 0.4 4.8 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Amino_oxidase PF01593.24 OEU09345.1 - 9.6e-09 35.0 0.0 6.5e-07 29.0 0.0 3.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OEU09345.1 - 2.9e-08 33.7 0.1 0.00059 19.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU09345.1 - 1.4e-07 31.6 0.0 4e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU09345.1 - 6.9e-06 25.5 0.1 0.021 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU09345.1 - 0.0048 16.9 0.3 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding SUIM_assoc PF16619.5 OEU09345.1 - 0.055 13.5 0.2 0.055 13.5 0.2 3.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Pyr_redox PF00070.27 OEU09345.1 - 0.14 12.8 0.1 3.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Med3 PF11593.8 OEU09345.1 - 0.16 11.1 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal FAD_binding_2 PF00890.24 OEU09345.1 - 0.19 10.8 0.5 0.36 9.9 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 OEU09346.1 - 3.5e-55 188.1 0.0 4.2e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU09346.1 - 7.4e-14 51.7 0.2 5.1e-13 49.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OEU09346.1 - 6.6e-05 22.2 0.1 0.00051 19.2 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OEU09346.1 - 9.4e-05 21.9 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU09346.1 - 0.0008 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU09346.1 - 0.0011 18.1 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OEU09346.1 - 0.0013 17.6 0.7 0.0019 17.0 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OEU09346.1 - 0.0034 16.7 0.1 0.033 13.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OEU09346.1 - 0.0083 15.4 1.8 0.017 14.4 0.0 2.2 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 OEU09346.1 - 0.022 13.5 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 MCRA family Pyr_redox PF00070.27 OEU09346.1 - 0.049 14.2 0.1 0.16 12.6 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU09346.1 - 0.055 13.0 0.1 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 OEU09346.1 - 0.091 12.6 0.1 0.091 12.6 0.1 1.8 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 OEU09346.1 - 0.18 11.6 0.7 0.34 10.8 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TMEM65 PF10507.9 OEU09347.1 - 2.1e-40 137.0 5.9 4e-40 136.2 5.9 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 GAF PF01590.26 OEU09347.1 - 1.3e-13 51.7 0.0 5.9e-13 49.6 0.0 2.1 2 1 0 2 2 2 1 GAF domain GAF_2 PF13185.6 OEU09347.1 - 0.0003 21.1 0.0 0.0048 17.2 0.0 2.2 2 0 0 2 2 2 1 GAF domain AAA_33 PF13671.6 OEU09347.1 - 0.033 14.3 0.3 0.068 13.3 0.3 1.4 1 0 0 1 1 1 0 AAA domain Rubis-subs-bind PF09273.11 OEU09348.1 - 2.5e-10 41.2 0.0 7.4e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OEU09348.1 - 6.6e-08 33.1 0.2 1.6e-06 28.6 0.0 2.3 1 1 1 2 2 2 1 SET domain CLIP_SPH_mas PF18398.1 OEU09348.1 - 0.051 14.0 0.1 0.2 12.1 0.1 2.0 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade EIF_2_alpha PF07541.12 OEU09348.1 - 0.077 13.1 0.0 9.1 6.4 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit TPT PF03151.16 OEU09349.1 - 4.3e-09 36.1 18.5 5.5e-09 35.8 18.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU09349.1 - 3e-08 33.9 23.2 1.6e-07 31.6 10.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family BNIP3 PF06553.12 OEU09349.1 - 7.3 6.2 7.0 1.8 8.2 3.8 1.6 2 0 0 2 2 2 0 BNIP3 Peptidase_C48 PF02902.19 OEU09350.1 - 7.4e-07 29.2 0.9 1.3e-06 28.4 0.9 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 OEU09350.1 - 0.0016 18.1 0.2 0.0024 17.5 0.2 1.3 1 0 0 1 1 1 1 Adenovirus endoprotease RVT_1 PF00078.27 OEU09351.1 - 3.4e-05 23.5 0.0 0.00017 21.2 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU09351.1 - 0.0018 17.8 0.0 0.0063 16.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU09351.1 - 0.017 15.8 1.0 0.053 14.2 1.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase WD40 PF00400.32 OEU09352.1 - 2e-09 37.9 5.8 0.02 15.8 0.1 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU09352.1 - 1.1e-05 25.7 0.0 1.2 9.5 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TauE PF01925.19 OEU09353.1 - 1.3e-30 106.8 27.6 1.5e-15 57.5 5.1 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE SAP PF02037.27 OEU09354.1 - 0.00067 19.4 0.2 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 SAP domain UPF0524 PF15823.5 OEU09354.1 - 0.17 11.3 3.6 2.2 7.7 1.1 2.6 2 0 0 2 2 2 0 UPF0524 of C3orf70 Sedlin_N PF04628.13 OEU09355.1 - 1.4e-39 135.2 0.3 1.5e-39 135.1 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OEU09355.1 - 3.8e-09 36.6 0.1 4.8e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family Pkinase_Tyr PF07714.17 OEU09357.1 - 9.6e-29 100.4 0.0 1.1e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU09357.1 - 2.6e-27 95.8 0.0 3.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU09357.1 - 0.00032 19.6 0.1 0.0006 18.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OEU09357.1 - 0.0054 15.7 0.0 0.0073 15.3 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OEU09357.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU09357.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltr_RsmB-F PF01189.17 OEU09358.1 - 1.9e-20 73.4 0.1 3.7e-18 65.9 0.1 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F XPG_I PF00867.18 OEU09358.1 - 0.027 14.8 1.0 0.11 12.9 0.0 2.5 3 1 0 3 3 3 0 XPG I-region Torus PF16131.5 OEU09359.1 - 1.4e-08 35.4 0.1 3.2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 OEU09359.1 - 1.3e-07 31.3 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OEU09359.1 - 2.1e-05 24.4 3.6 5.3e-05 23.1 3.6 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OEU09359.1 - 2.4e-05 24.1 2.0 2.4e-05 24.1 2.0 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) REC114-like PF15165.6 OEU09359.1 - 0.0085 15.9 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like zf-CCCH_4 PF18044.1 OEU09359.1 - 0.0095 15.7 2.1 0.026 14.3 2.1 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OEU09359.1 - 0.019 15.2 0.1 0.019 15.2 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger containing family Nup35_RRM_2 PF14605.6 OEU09359.1 - 0.019 14.9 0.0 0.061 13.3 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_2 PF14608.6 OEU09359.1 - 0.04 14.4 2.9 0.1 13.1 2.9 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger IL33 PF15095.6 OEU09359.1 - 0.068 12.6 1.1 0.12 11.8 0.5 1.6 1 1 1 2 2 2 0 Interleukin 33 FYVE PF01363.21 OEU09359.1 - 1.5 9.1 7.3 0.73 10.0 3.9 2.3 2 1 0 2 2 2 0 FYVE zinc finger HAD_SAK_2 PF18143.1 OEU09360.1 - 8.5e-25 87.7 0.1 9.9e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins HATPase_c PF02518.26 OEU09361.1 - 1.7e-08 34.9 0.1 4.9e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OEU09361.1 - 0.015 15.1 11.9 0.072 12.9 11.9 2.2 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 OEU09361.1 - 5.1 7.1 8.5 5.2 7.0 2.7 3.4 2 1 0 2 2 2 0 GHKL domain CPSF73-100_C PF11718.8 OEU09363.1 - 4e-33 114.8 0.0 6e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OEU09363.1 - 9.6e-30 103.1 0.0 1.9e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OEU09363.1 - 1.1e-17 64.2 0.0 2.4e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU09363.1 - 4.5e-14 52.9 1.6 1.4e-13 51.3 1.4 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OEU09363.1 - 1.3e-13 50.6 0.0 3.3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OEU09363.1 - 6.3e-08 32.4 0.2 3.2e-07 30.1 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OEU09363.1 - 0.00027 20.9 0.1 0.00076 19.4 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 OEU09363.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family Ly49 PF08391.10 OEU09364.1 - 0.0075 16.6 1.6 0.025 15.0 0.1 2.5 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region DUF4131 PF13567.6 OEU09364.1 - 9.5 5.8 6.1 15 5.2 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ank_4 PF13637.6 OEU09367.1 - 3.2e-12 46.7 0.0 4.2e-07 30.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU09367.1 - 4.9e-10 39.9 0.1 3e-09 37.3 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU09367.1 - 5.1e-07 29.8 0.2 2.4e-05 24.5 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU09367.1 - 8.3e-06 25.8 0.0 0.00025 21.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OEU09367.1 - 7.8e-05 22.9 0.0 0.0017 18.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat zf-trcl PF13451.6 OEU09368.1 - 0.031 14.2 0.6 0.084 12.8 0.6 1.8 1 0 0 1 1 1 0 Probable zinc-ribbon domain Annexin PF00191.20 OEU09368.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Annexin NAD_binding_6 PF08030.12 OEU09368.1 - 0.075 13.2 0.1 2 8.5 0.0 2.5 2 1 0 2 2 2 0 Ferric reductase NAD binding domain KCNQC3-Ank-G_bd PF11956.8 OEU09368.1 - 0.32 11.3 4.5 1.5 9.1 4.1 2.0 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 PPR_2 PF13041.6 OEU09369.1 - 2.3e-49 165.4 14.3 1e-12 48.0 0.0 13.3 11 2 3 14 14 14 9 PPR repeat family PPR_3 PF13812.6 OEU09369.1 - 2.2e-45 152.6 0.1 4.8e-11 42.6 0.0 12.4 10 2 2 13 13 13 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU09369.1 - 1.6e-44 149.3 0.2 0.00082 19.0 0.0 14.0 14 1 0 14 14 14 10 PPR repeat PPR PF01535.20 OEU09369.1 - 1.7e-37 125.0 33.9 0.0001 22.3 0.0 15.2 15 2 0 15 15 15 9 PPR repeat PPR_long PF17177.4 OEU09369.1 - 4.1e-13 49.2 0.0 0.0017 17.7 0.0 5.4 2 2 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OEU09369.1 - 0.00093 19.7 0.0 5.2 7.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OEU09369.1 - 0.00098 19.1 0.1 0.095 12.6 0.0 3.2 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 OEU09369.1 - 0.18 11.9 0.5 64 3.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 OEU09370.1 - 3.5e-09 37.1 9.2 5.1e-06 27.1 0.4 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat Glyco_transf_64 PF09258.10 OEU09371.1 - 5.3e-13 48.8 0.2 6.9e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.26 OEU09371.1 - 0.007 16.2 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Fringe PF02434.16 OEU09371.1 - 0.053 12.9 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Fringe-like DUF983 PF06170.12 OEU09372.1 - 0.28 11.6 1.0 22 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Ubie_methyltran PF01209.18 OEU09373.1 - 6.7e-77 257.9 0.2 1.1e-75 254.0 0.2 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OEU09373.1 - 1.2e-16 61.2 0.1 4.7e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU09373.1 - 3.9e-16 59.5 0.0 9.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU09373.1 - 6.7e-14 51.9 0.0 3.1e-13 49.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU09373.1 - 3.1e-12 47.1 0.0 7.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU09373.1 - 4.1e-08 33.2 0.0 6.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU09373.1 - 0.025 14.4 0.0 0.099 12.5 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 OEU09373.1 - 0.08 12.5 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PI3_PI4_kinase PF00454.27 OEU09374.1 - 9e-48 163.3 0.0 2.5e-46 158.5 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OEU09374.1 - 7.6e-12 44.8 0.1 1.6e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 FATC domain Ank_2 PF12796.7 OEU09375.1 - 2.6e-10 40.7 0.1 5.7e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU09375.1 - 8.4e-08 32.3 0.1 0.011 16.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU09375.1 - 4.8e-06 26.8 0.8 0.012 16.0 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OEU09375.1 - 0.0081 16.7 0.4 0.99 10.1 0.0 3.1 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU09375.1 - 0.02 15.4 0.8 1.8 9.4 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeat Ribosomal_S17_N PF16205.5 OEU09376.1 - 2.3e-30 104.8 1.1 3.7e-30 104.1 0.4 1.8 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OEU09376.1 - 1.2e-27 95.8 0.9 2.2e-27 94.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 CdiA_C PF18451.1 OEU09376.1 - 0.012 15.8 0.2 0.027 14.7 0.0 1.7 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Ion_trans PF00520.31 OEU09377.1 - 8.3e-14 51.4 25.8 8.3e-14 51.4 25.8 2.0 2 0 0 2 2 2 1 Ion transport protein PH PF00169.29 OEU09378.1 - 1.2e-13 51.5 0.7 2.5e-08 34.4 0.0 2.8 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 OEU09378.1 - 0.00018 21.9 3.8 0.027 14.9 0.2 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OEU09378.1 - 0.00026 21.2 0.8 0.0032 17.7 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain MFS_1 PF07690.16 OEU09379.1 - 3.8e-44 151.1 29.9 1e-43 149.6 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU09379.1 - 8.2e-07 28.2 8.6 8.2e-07 28.2 8.6 3.1 2 2 2 4 4 4 2 Sugar (and other) transporter OATP PF03137.20 OEU09379.1 - 8.1e-06 24.4 5.5 0.00053 18.4 0.1 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family SNF2_N PF00176.23 OEU09380.1 - 4.2e-73 246.1 0.1 7.1e-73 245.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OEU09380.1 - 2.4e-35 121.0 4.6 2.4e-35 121.0 4.6 2.3 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 OEU09380.1 - 2.5e-18 66.4 0.1 1e-17 64.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU09380.1 - 1.4e-10 41.4 0.0 7.2e-10 39.1 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HAND PF09110.11 OEU09380.1 - 1.1e-06 29.3 1.9 4.7e-06 27.3 1.5 2.3 2 0 0 2 2 2 1 HAND DEAD PF00270.29 OEU09380.1 - 7e-05 22.7 0.1 0.00054 19.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OEU09380.1 - 0.026 14.2 0.0 0.11 12.2 0.0 2.1 1 1 0 1 1 1 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 OEU09380.1 - 0.038 13.2 0.0 0.099 11.8 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 FeoB_Cyto PF17910.1 OEU09380.1 - 0.3 11.7 3.6 0.16 12.5 0.5 2.2 2 0 0 2 2 2 0 FeoB cytosolic helical domain ACPS PF01648.20 OEU09382.1 - 3.9e-13 49.5 0.0 7.6e-13 48.6 0.0 1.5 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 OEU09382.1 - 2.4e-08 34.0 0.0 4.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain RE_Bsp6I PF09504.10 OEU09382.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Peptidase_M1 PF01433.20 OEU09383.1 - 9.9e-49 165.8 0.1 1.4e-48 165.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OEU09383.1 - 6.1e-37 126.2 0.0 1.3e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OEU09383.1 - 1.2e-17 64.7 0.2 1.9e-17 64.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 OEU09383.1 - 0.56 10.6 3.9 3.8 7.9 1.5 3.0 2 1 0 2 2 2 0 M61 glycyl aminopeptidase UbiA PF01040.18 OEU09384.1 - 2.6e-18 66.2 1.2 3.4e-18 65.9 1.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family 7tm_3 PF00003.22 OEU09384.1 - 0.019 14.7 0.5 0.026 14.2 0.3 1.4 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Thioredoxin PF00085.20 OEU09386.1 - 6.1e-14 51.9 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU09386.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain HTH_6 PF01418.17 OEU09386.1 - 0.15 12.1 0.0 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DEAD PF00270.29 OEU09387.1 - 4e-18 65.8 0.0 7.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OEU09387.1 - 4.7e-08 33.2 0.0 7.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU09387.1 - 5.1e-07 30.0 0.0 1.3e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OEU09387.1 - 0.0048 17.2 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Peptidase_C48 PF02902.19 OEU09389.1 - 3.9e-14 53.0 2.9 5.9e-13 49.2 0.8 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Copine PF07002.16 OEU09389.1 - 0.053 13.0 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Copine DNA_primase_lrg PF04104.14 OEU09390.1 - 0.28 10.5 3.7 0.16 11.3 0.9 1.9 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Ago_N_1 PF18351.1 OEU09390.1 - 0.32 11.4 3.1 1.3 9.5 0.2 3.5 3 1 0 4 4 4 0 Fungal Argonaute N-terminal domain DUF563 PF04577.14 OEU09391.1 - 2.8e-09 37.4 0.0 6.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Paf1 PF03985.13 OEU09393.1 - 1.5e-27 96.7 12.9 4.7e-24 85.2 8.8 3.0 2 1 0 2 2 2 2 Paf1 Lysine_decarbox PF03641.14 OEU09394.1 - 1.2e-19 70.7 0.0 5.2e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OEU09394.1 - 1.2e-11 44.4 0.0 7.2e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 SLOG cluster4 family Peptidase_C1 PF00112.23 OEU09395.1 - 1.7e-38 132.9 0.7 4.4e-38 131.6 0.7 1.6 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OEU09395.1 - 0.009 14.8 0.5 0.009 14.8 0.5 1.4 2 0 0 2 2 2 1 Peptidase C1-like family PPR_3 PF13812.6 OEU09396.1 - 2.1e-10 40.5 0.2 2.2e-06 27.7 0.0 3.3 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 OEU09396.1 - 3.4e-08 33.5 0.1 0.00042 20.5 0.0 4.2 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 OEU09396.1 - 5.5e-07 29.4 1.7 0.87 10.0 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 OEU09396.1 - 2.2e-05 24.1 0.5 0.038 13.7 0.1 3.7 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 OEU09396.1 - 0.0029 17.0 0.0 0.062 12.7 0.0 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 OEU09396.1 - 0.0096 15.8 0.0 0.29 11.0 0.0 2.8 1 1 0 2 2 2 1 Mitochondrial ATPase expression TRAUB PF08164.12 OEU09398.1 - 5.4e-21 74.9 1.1 5.4e-21 74.9 1.1 3.1 2 1 2 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OEU09398.1 - 4.9e-09 37.0 17.2 8e-09 36.3 14.0 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor POX PF07526.11 OEU09398.1 - 8 7.0 8.4 0.77 10.3 0.1 2.6 2 1 0 2 2 2 0 Associated with HOX Inositol_P PF00459.25 OEU09399.1 - 1.2e-20 74.2 0.0 2.1e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family EcKinase PF02958.20 OEU09399.1 - 2.7e-10 40.0 0.0 2.3e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OEU09399.1 - 5e-08 32.2 0.0 7.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 OEU09399.1 - 6.2e-08 32.9 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OEU09399.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_12 PF13424.6 OEU09400.1 - 7.5e-47 157.5 11.3 1.6e-15 57.1 0.5 3.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OEU09400.1 - 8.2e-34 114.5 5.9 6.7e-09 35.3 0.1 5.4 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU09400.1 - 1.7e-21 75.1 0.7 9.8e-05 22.0 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU09400.1 - 3.3e-19 67.4 2.7 0.00012 22.0 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU09400.1 - 3.5e-19 67.4 5.9 0.0012 18.7 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OEU09400.1 - 3.1e-13 49.2 0.5 0.0024 17.5 0.0 5.5 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.6 OEU09400.1 - 6.1e-11 41.6 1.4 0.042 14.1 0.2 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OEU09400.1 - 7.5e-11 41.9 2.2 0.39 11.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU09400.1 - 2.5e-10 39.6 0.9 0.031 13.7 0.0 4.9 5 0 0 5 5 5 2 SHNi-TPR TPR_16 PF13432.6 OEU09400.1 - 3.9e-08 33.8 2.6 0.0011 19.6 0.2 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU09400.1 - 4.8e-08 32.8 0.0 0.47 11.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU09400.1 - 1.9e-07 31.1 0.2 0.0025 17.9 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU09400.1 - 1.2e-06 28.2 2.2 1.2e-06 28.2 2.2 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_4 PF07721.14 OEU09400.1 - 7.4e-06 26.1 1.4 0.28 11.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU09400.1 - 0.00016 22.1 3.0 0.34 11.4 0.2 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU09400.1 - 0.0006 20.3 2.9 7.4 7.4 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU09400.1 - 0.0012 19.0 0.3 0.79 10.0 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 OEU09400.1 - 0.0037 17.3 2.3 2 8.6 0.1 4.3 3 2 0 5 5 5 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 OEU09400.1 - 0.0039 17.2 0.2 0.09 12.9 0.0 3.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 OEU09400.1 - 0.006 16.5 1.4 0.73 9.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 OEU09400.1 - 0.011 15.5 0.2 2.9 7.6 0.0 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain DUF5113 PF17140.4 OEU09400.1 - 0.013 15.3 0.0 4.6 7.0 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) RPN7 PF10602.9 OEU09400.1 - 0.047 13.4 0.2 3.7 7.2 0.0 3.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 TAP42 PF04177.12 OEU09401.1 - 2.8e-52 177.8 8.2 3.3e-52 177.6 8.2 1.0 1 0 0 1 1 1 1 TAP42-like family SecD-TM1 PF13721.6 OEU09401.1 - 0.033 14.6 0.3 0.089 13.3 0.3 1.7 1 0 0 1 1 1 0 SecD export protein N-terminal TM region AhpC-TSA PF00578.21 OEU09401.1 - 0.035 14.0 0.2 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 AhpC/TSA family Chloroa_b-bind PF00504.21 OEU09402.1 - 3.3e-28 99.2 0.0 4.4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ni_hydr_CYTB PF01292.20 OEU09402.1 - 0.085 12.5 0.1 7.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Chloroa_b-bind PF00504.21 OEU09403.1 - 1.3e-28 100.5 0.2 1.8e-28 100.1 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ni_hydr_CYTB PF01292.20 OEU09403.1 - 0.045 13.3 0.1 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Tri3 PF07428.11 OEU09403.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Methyltransf_25 PF13649.6 OEU09404.1 - 1.6e-07 31.9 0.0 8e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain TPR_12 PF13424.6 OEU09404.1 - 5.8e-07 29.7 5.3 0.012 15.9 0.0 4.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU09404.1 - 2.7e-06 27.0 0.9 0.15 12.1 0.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_31 PF13847.6 OEU09404.1 - 6e-06 26.1 0.0 2.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU09404.1 - 1.4e-05 25.0 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPR_2 PF07719.17 OEU09404.1 - 1.7e-05 24.6 6.8 0.67 10.2 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Methyltransf_11 PF08241.12 OEU09404.1 - 4.6e-05 24.0 0.0 0.00012 22.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FAT PF02259.23 OEU09404.1 - 6.6e-05 22.3 0.4 0.035 13.3 0.0 2.1 1 1 1 2 2 2 2 FAT domain TPR_14 PF13428.6 OEU09404.1 - 0.00014 22.4 3.6 9.8 7.3 0.0 5.6 5 1 1 6 6 5 0 Tetratricopeptide repeat Methyltransf_12 PF08242.12 OEU09404.1 - 0.00023 21.8 0.0 0.00055 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MIT PF04212.18 OEU09404.1 - 0.00056 19.9 5.4 0.036 14.1 0.1 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 OEU09404.1 - 0.0015 19.1 0.5 0.04 14.6 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU09404.1 - 0.002 17.8 13.8 0.66 9.7 0.0 5.4 6 0 0 6 6 6 2 TPR repeat TPR_17 PF13431.6 OEU09404.1 - 0.0094 16.3 2.9 1.1 9.8 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.6 OEU09404.1 - 0.026 13.9 1.6 2.5 7.5 0.5 2.6 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 OEU09404.1 - 0.031 14.5 9.0 1.2 9.6 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat NodS PF05401.11 OEU09404.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) HUN PF08729.10 OEU09404.1 - 0.058 13.4 2.0 0.23 11.5 2.0 2.0 1 0 0 1 1 1 0 HPC2 and ubinuclein domain P22_AR_C PF10548.9 OEU09404.1 - 0.065 13.4 0.1 57 4.0 0.1 3.5 3 0 0 3 3 3 0 P22AR C-terminal domain TPR_1 PF00515.28 OEU09404.1 - 0.12 12.2 20.6 0.26 11.2 1.9 6.0 7 1 0 7 7 6 0 Tetratricopeptide repeat MTS PF05175.14 OEU09404.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 OEU09405.1 - 1.2e-62 211.6 0.3 1.5e-62 211.4 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09405.1 - 3.1e-18 66.0 0.0 4.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU09405.1 - 4.6e-06 26.7 0.2 1.4e-05 25.1 0.1 1.8 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU09405.1 - 0.023 14.1 0.2 0.04 13.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU09405.1 - 0.025 13.4 0.1 0.074 11.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 OEU09405.1 - 0.027 14.0 0.1 0.054 13.1 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2459 PF09601.10 OEU09405.1 - 0.091 12.6 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Aconitase_B_N PF11791.8 OEU09405.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain WD40 PF00400.32 OEU09406.1 - 9e-05 23.2 0.2 0.017 16.0 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 OEU09406.1 - 0.11 12.5 0.0 0.59 10.2 0.0 2.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pro_isomerase PF00160.21 OEU09407.1 - 5.3e-51 173.0 0.0 6.3e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Chorismate_synt PF01264.21 OEU09408.1 - 2.9e-137 456.8 1.3 3.4e-137 456.5 1.3 1.0 1 0 0 1 1 1 1 Chorismate synthase adh_short_C2 PF13561.6 OEU09410.1 - 1.9e-45 155.2 2.0 1.1e-42 146.2 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU09410.1 - 1.2e-07 31.4 1.7 4.9e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 OEU09410.1 - 0.00012 21.5 0.2 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region PGA_cap PF09587.10 OEU09410.1 - 0.11 11.9 0.0 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Methyltransf_4 PF02390.17 OEU09411.1 - 2.6e-12 46.6 0.0 5.5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PPR_2 PF13041.6 OEU09411.1 - 9.5e-10 38.5 0.4 6.4e-06 26.3 0.0 4.2 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 OEU09411.1 - 7.7e-07 29.0 6.9 0.0033 17.5 0.1 5.5 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.7 OEU09411.1 - 0.00057 19.5 1.8 2.5 7.9 0.1 4.4 5 0 0 5 5 5 2 PPR repeat DUF3670 PF12419.8 OEU09412.1 - 0.035 14.0 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 SNF2 Helicase protein Miga PF10265.9 OEU09412.1 - 0.072 12.1 7.9 0.093 11.7 7.9 1.0 1 0 0 1 1 1 0 Mitoguardin MRI PF15325.6 OEU09412.1 - 2.7 9.1 6.1 29 5.8 0.0 3.1 3 0 0 3 3 3 0 Modulator of retrovirus infection Pkinase PF00069.25 OEU09413.1 - 6.3e-39 133.9 0.0 7.3e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09413.1 - 2.3e-15 56.6 0.0 8.4e-15 54.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU09413.1 - 3.4e-05 23.9 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU09413.1 - 0.00074 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OEU09413.1 - 0.044 12.7 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OEU09413.1 - 0.062 12.1 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OEU09413.1 - 0.26 10.9 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family KA1 PF02149.19 OEU09415.1 - 0.015 15.1 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 Kinase associated domain 1 HGTP_anticodon PF03129.20 OEU09415.1 - 0.018 15.2 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Anticodon binding domain Glyco_transf_25 PF01755.17 OEU09416.1 - 3.4e-06 27.1 0.2 0.02 14.8 0.2 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-RING_4 PF14570.6 OEU09417.1 - 1.9e-22 78.8 14.0 3.6e-22 77.9 14.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OEU09417.1 - 2.4e-06 27.3 10.7 2.4e-06 27.3 10.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 OEU09417.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 OEU09417.1 - 0.03 14.4 5.6 0.06 13.5 5.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 OEU09417.1 - 0.37 10.7 6.5 0.94 9.4 6.5 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 OEU09417.1 - 3.9 7.4 12.6 0.6 10.0 3.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Mastoparan PF08249.11 OEU09419.1 - 0.2 12.5 0.7 0.46 11.3 0.7 1.7 1 0 0 1 1 1 0 Mastoparan protein Frataxin_Cyay PF01491.16 OEU09420.1 - 8.6e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Frataxin-like domain DnaG_DnaB_bind PF08278.11 OEU09420.1 - 0.11 13.0 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Cupin_2 PF07883.11 OEU09423.1 - 1.7e-06 27.7 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OEU09423.1 - 0.00079 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OEU09423.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) NUDIX PF00293.28 OEU09424.1 - 2.9e-08 33.8 0.0 4.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ras PF00071.22 OEU09425.1 - 1.7e-60 203.3 0.0 1.9e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU09425.1 - 8e-34 116.4 0.0 1.3e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU09425.1 - 2.5e-14 53.1 0.0 2.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU09425.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU09425.1 - 0.0015 18.5 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OEU09425.1 - 0.0078 15.6 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATPase PF06745.13 OEU09425.1 - 0.15 11.4 0.0 12 5.1 0.0 2.0 2 0 0 2 2 2 0 KaiC NOC3p PF07540.11 OEU09426.1 - 4.7e-21 75.0 1.8 7.3e-21 74.4 0.3 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 OEU09426.1 - 5.3e-21 75.4 1.0 1.3e-20 74.1 0.1 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Katanin_con80 PF13925.6 OEU09426.1 - 2.9 7.9 6.5 2.5 8.1 0.3 3.4 3 1 1 4 4 4 0 con80 domain of Katanin SWIRM PF04433.17 OEU09428.1 - 2.2e-14 53.6 0.0 2.4e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 SWIRM domain PP2C PF00481.21 OEU09429.1 - 1e-36 126.9 0.0 1.2e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU09429.1 - 1.5e-06 28.3 0.4 7.8e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OEU09429.1 - 5e-06 26.3 0.0 3.1e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C zinc_ribbon_16 PF17034.5 OEU09429.1 - 0.24 11.6 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family DHHC PF01529.20 OEU09430.1 - 6.5e-33 113.7 13.0 1.1e-32 113.0 13.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase TauE PF01925.19 OEU09431.1 - 4.8e-28 98.4 20.0 2.2e-15 57.0 0.4 2.8 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE MFS_1 PF07690.16 OEU09431.1 - 4.4e-05 22.6 21.5 0.14 11.1 0.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3169 PF11368.8 OEU09431.1 - 0.8 9.2 0.0 0.8 9.2 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3169) Adap_comp_sub PF00928.21 OEU09432.1 - 8.5e-85 284.3 0.1 1.1e-84 283.9 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OEU09432.1 - 7.9e-08 32.3 1.4 1.4e-07 31.5 1.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OEU09432.1 - 0.005 16.3 0.1 0.0096 15.4 0.0 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain cwf21 PF08312.12 OEU09433.1 - 0.0053 16.9 11.1 0.0053 16.9 11.1 3.2 3 0 0 3 3 3 1 cwf21 domain Adaptin_binding PF10199.9 OEU09434.1 - 0.00073 20.1 4.1 0.0013 19.3 4.1 1.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Pheromone PF08015.11 OEU09434.1 - 0.024 15.7 0.1 2 9.5 0.0 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone Acyl-CoA_ox_N PF14749.6 OEU09434.1 - 0.059 13.9 2.0 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal IKKbetaNEMObind PF12179.8 OEU09434.1 - 0.13 12.4 0.3 0.13 12.4 0.3 1.9 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Clat_adaptor_s PF01217.20 OEU09435.1 - 4.1e-37 127.3 0.5 5.1e-37 127.0 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ERGIC_N PF13850.6 OEU09436.1 - 1.8e-19 69.9 0.4 3.6e-19 68.9 0.4 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 OEU09436.1 - 1.8e-19 70.5 0.1 6.9e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 OEU09436.1 - 1.6e-11 44.1 0.0 5.7e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin CxC6 PF18721.1 OEU09438.1 - 0.00027 21.1 40.8 0.063 13.5 5.8 4.6 1 1 4 5 5 5 4 CxC6 like cysteine cluster associated with KDZ transposases Transp_Tc5_C PF04236.15 OEU09438.1 - 0.0053 17.1 34.2 1 9.7 0.0 6.6 1 1 6 7 7 7 4 Tc5 transposase C-terminal domain zf-C3Hc3H PF13891.6 OEU09438.1 - 3.8 8.0 36.3 31 5.1 0.5 6.8 5 2 0 5 5 5 0 Potential DNA-binding domain DEAD PF00270.29 OEU09439.1 - 1.9e-19 70.1 0.0 5.8e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU09439.1 - 5.3e-19 68.6 0.0 2.1e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 OEU09439.1 - 4.9e-14 52.1 0.1 2.8e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 RQC domain zf-GRF PF06839.12 OEU09439.1 - 1.7e-12 47.2 3.6 4.7e-12 45.8 3.6 1.9 1 0 0 1 1 1 1 GRF zinc finger RecQ_Zn_bind PF16124.5 OEU09439.1 - 9.9e-12 45.4 6.2 9.9e-12 45.4 6.2 2.6 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 OEU09439.1 - 6.2e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 OEU09439.1 - 0.00068 19.7 0.1 0.0038 17.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RVT_1 PF00078.27 OEU09440.1 - 1.1e-07 31.6 0.0 3.9e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU09440.1 - 0.053 14.2 1.1 0.21 12.3 1.1 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Methyltransf_12 PF08242.12 OEU09441.1 - 6.7e-06 26.8 0.0 3.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU09441.1 - 8.1e-05 23.2 0.0 0.00072 20.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU09441.1 - 0.0028 17.5 0.0 0.017 15.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU09441.1 - 0.014 16.1 0.0 0.092 13.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OEU09441.1 - 0.015 15.1 0.0 0.063 13.1 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 OEU09443.1 - 2.8e-69 233.4 0.1 3.5e-69 233.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09443.1 - 4e-36 124.6 0.1 9.9e-36 123.3 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU09443.1 - 0.00026 20.4 0.2 0.0004 19.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OEU09443.1 - 0.00059 18.9 0.2 0.00094 18.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OEU09443.1 - 0.0062 16.5 0.3 0.77 9.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OEU09443.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OEU09443.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.8 2 1 0 2 2 2 0 Kinase-like MIEAP PF16026.5 OEU09444.1 - 0.99 9.6 8.2 0.35 11.1 4.1 2.3 2 0 0 2 2 2 0 Mitochondria-eating protein GlcNAc PF11397.8 OEU09445.1 - 3.1e-66 224.2 0.5 3.5e-53 181.3 0.4 2.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Josephin PF02099.17 OEU09446.1 - 9.4e-40 136.4 0.0 1.3e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Josephin UBX PF00789.20 OEU09446.1 - 1.5e-09 37.9 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 OEU09446.1 - 0.0031 17.3 1.4 0.0072 16.2 1.4 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Esterase PF00756.20 OEU09447.1 - 9.9e-47 159.7 0.0 1.2e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OEU09447.1 - 0.00038 19.8 0.1 0.0052 16.1 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OEU09447.1 - 0.041 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1857 PF08982.11 OEU09447.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Flavi_NS1 PF00948.21 OEU09447.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Ribosomal_L38e PF01781.18 OEU09448.1 - 1.7e-33 114.5 3.0 1.9e-33 114.4 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family IF3_N PF05198.16 OEU09448.1 - 0.087 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain CDKN3 PF05706.12 OEU09449.1 - 1.7e-07 31.1 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF442 PF04273.13 OEU09449.1 - 0.00024 21.2 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative phosphatase (DUF442) DSPc PF00782.20 OEU09449.1 - 0.0007 19.4 0.1 0.0012 18.6 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OEU09449.1 - 0.0026 17.8 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DnaA_N PF11638.8 OEU09449.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain Glyco_tranf_2_4 PF13704.6 OEU09449.1 - 0.17 12.4 0.1 0.48 11.0 0.1 1.7 1 1 1 2 2 2 0 Glycosyl transferase family 2 Fe-ADH_2 PF13685.6 OEU09449.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Sigma54_activ_2 PF14532.6 OEU09449.1 - 0.2 11.8 0.0 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Atracotoxin PF05353.11 OEU09450.1 - 0.028 14.5 4.9 0.028 14.5 4.9 2.1 2 0 0 2 2 2 0 Delta Atracotoxin Toxin_12 PF07740.12 OEU09450.1 - 0.057 14.1 7.8 0.057 14.1 7.8 2.6 2 0 0 2 2 2 0 Ion channel inhibitory toxin zf-C3HC4_2 PF13923.6 OEU09451.1 - 2.3e-08 33.7 5.3 4.9e-08 32.7 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU09451.1 - 1.6e-07 31.1 6.0 1.6e-07 31.1 6.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU09451.1 - 4.4e-07 29.8 6.3 1.2e-06 28.4 6.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU09451.1 - 9.1e-07 28.9 7.1 2.2e-06 27.7 7.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OEU09451.1 - 1.3e-06 28.1 3.9 2.2e-06 27.4 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 OEU09451.1 - 2.2e-06 27.4 2.0 3.4e-06 26.8 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OEU09451.1 - 6.2e-06 26.1 7.2 1.2e-05 25.2 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OEU09451.1 - 0.00011 22.4 7.1 0.00025 21.3 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU09451.1 - 0.00012 21.9 5.9 0.00022 21.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU09451.1 - 0.002 18.0 9.2 0.21 11.5 10.0 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OEU09451.1 - 0.0039 17.4 6.4 0.024 14.9 6.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain IBR PF01485.21 OEU09451.1 - 0.19 12.0 8.2 0.35 11.1 4.6 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn-C2H2_12 PF18112.1 OEU09451.1 - 0.38 11.3 0.4 0.38 11.3 0.4 2.1 2 0 0 2 2 1 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 OEU09451.1 - 0.44 10.7 5.8 0.92 9.7 5.7 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 DARPP-32 PF05395.12 OEU09451.1 - 0.53 10.5 12.4 0.85 9.8 12.4 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 zf-C3HC4_5 PF17121.5 OEU09451.1 - 1.1 9.3 10.6 4.6 7.2 10.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.12 OEU09451.1 - 1.5 7.0 29.1 2 6.6 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OEU09451.1 - 1.5 8.1 21.5 1.9 7.8 21.5 1.1 1 0 0 1 1 1 0 BUD22 CaMBD PF02888.16 OEU09451.1 - 3.5 7.9 6.6 0.39 11.0 1.2 2.2 2 1 1 3 3 2 0 Calmodulin binding domain Peptidase_M17 PF00883.21 OEU09452.1 - 6.1e-109 364.1 0.4 7.9e-109 363.7 0.4 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 OEU09452.1 - 2.3e-07 30.7 0.1 2e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain SAP PF02037.27 OEU09453.1 - 2.8e-08 33.3 0.2 6.2e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 SAP domain SRP-alpha_N PF04086.13 OEU09453.1 - 0.92 9.4 18.1 1.3 8.9 18.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SBF PF01758.16 OEU09454.1 - 9.6e-24 84.1 14.8 9.6e-24 84.1 14.8 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 OEU09454.1 - 0.0037 15.7 2.9 0.0037 15.7 2.9 1.8 1 1 1 2 2 2 1 Membrane transport protein DUF3742 PF12553.8 OEU09454.1 - 0.037 14.1 0.2 0.037 14.1 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) SBF PF01758.16 OEU09455.1 - 2.8e-22 79.3 19.9 3e-22 79.2 11.0 2.6 1 1 1 2 2 2 2 Sodium Bile acid symporter family Mem_trans PF03547.18 OEU09455.1 - 0.0013 17.2 3.5 0.0013 17.2 3.5 2.4 2 0 0 2 2 2 2 Membrane transport protein CoA_binding_3 PF13727.6 OEU09455.1 - 0.063 13.3 0.2 0.063 13.3 0.2 2.0 1 1 1 2 2 2 0 CoA-binding domain DUF4234 PF14018.6 OEU09455.1 - 3.7 7.7 8.3 0.48 10.6 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF1974 PF09317.11 OEU09457.1 - 8.8e-42 143.6 0.0 2.3e-41 142.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 OEU09457.1 - 3.7e-15 56.6 0.0 8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OEU09457.1 - 3.3e-08 33.9 0.6 1.6e-07 31.6 0.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OEU09457.1 - 3.5e-07 30.3 0.0 5.6e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Alpha_kinase PF02816.18 OEU09458.1 - 2.9e-42 144.9 0.0 7e-42 143.6 0.0 1.7 1 0 0 1 1 1 1 Alpha-kinase family Ssl1 PF04056.14 OEU09459.1 - 1.8e-53 181.2 0.0 2.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 OEU09459.1 - 1.8e-15 56.9 16.0 1.4e-14 54.0 10.5 2.8 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 OEU09459.1 - 2.8e-08 34.4 0.0 8.3e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.21 OEU09459.1 - 0.0017 18.5 7.8 0.0017 18.5 7.8 2.6 3 0 0 3 3 2 1 IBR domain, a half RING-finger domain zinc_ribbon_10 PF10058.9 OEU09459.1 - 0.0065 16.2 3.1 1.2 8.9 1.1 3.0 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein zf-4CXXC_R1 PF10497.9 OEU09459.1 - 0.0097 16.1 4.9 0.027 14.7 4.9 1.8 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DZR PF12773.7 OEU09459.1 - 0.15 12.1 18.5 1.2e+02 2.8 18.5 3.3 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 OEU09459.1 - 1.5 9.0 17.3 0.066 13.4 9.8 2.5 2 0 0 2 2 2 0 B-box zinc finger C1_2 PF03107.16 OEU09459.1 - 2.2 8.6 11.8 2.2 8.7 4.5 3.3 2 1 1 3 3 3 0 C1 domain zf-AN1 PF01428.16 OEU09459.1 - 3.1 8.0 16.3 4.9 7.4 9.3 2.9 2 0 0 2 2 2 0 AN1-like Zinc finger zinc_ribbon_15 PF17032.5 OEU09459.1 - 3.4 8.5 16.1 5.5 7.8 0.3 3.0 2 1 0 2 2 2 0 zinc-ribbon family zf_UBZ PF18439.1 OEU09459.1 - 4.7 6.9 7.6 3.2 7.4 0.1 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 OEU09460.1 - 0.0064 15.9 0.0 0.051 12.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain adh_short_C2 PF13561.6 OEU09461.1 - 1e-43 149.6 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU09461.1 - 2.3e-40 138.2 0.0 2.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU09461.1 - 2e-10 40.9 0.0 3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU09461.1 - 0.00066 18.9 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OEU09461.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 OEU09461.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Dicty_REP PF05086.12 OEU09463.1 - 0.00015 19.9 2.1 0.00016 19.8 2.1 1.3 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein ubiquitin PF00240.23 OEU09463.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CDC45 PF02724.14 OEU09463.1 - 2.2 6.5 11.1 2.8 6.1 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SGS PF05002.15 OEU09464.1 - 1.6e-32 111.4 5.3 3.3e-32 110.4 5.3 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OEU09464.1 - 5.9e-12 46.4 1.6 1.1e-11 45.6 0.2 2.1 3 0 0 3 3 3 1 CS domain SWM_repeat PF13753.6 OEU09464.1 - 0.059 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative flagellar system-associated repeat PP2C PF00481.21 OEU09465.1 - 4.9e-07 29.6 0.1 0.027 14.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 OEU09465.1 - 3.4e-05 23.8 0.0 5.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OEU09465.1 - 0.04 13.6 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C PH PF00169.29 OEU09466.1 - 1.2e-12 48.3 0.7 7.2e-12 45.7 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OEU09466.1 - 0.00033 21.1 0.0 0.0027 18.1 0.0 2.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OEU09466.1 - 0.0014 18.8 0.0 0.0069 16.6 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Csm1_N PF18504.1 OEU09466.1 - 0.0029 17.9 4.4 0.0029 17.9 4.4 4.4 5 0 0 5 5 5 1 Csm1 N-terminal domain ATG16 PF08614.11 OEU09466.1 - 0.011 16.0 3.0 0.011 16.0 3.0 5.3 4 2 0 4 4 4 0 Autophagy protein 16 (ATG16) CheZ PF04344.13 OEU09466.1 - 0.018 15.0 0.9 0.018 15.0 0.9 2.5 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ Phage_RpbA PF10789.9 OEU09466.1 - 0.03 14.4 0.5 0.12 12.4 0.5 2.1 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA YqjK PF13997.6 OEU09466.1 - 0.16 12.3 0.5 9.7 6.5 0.0 2.6 2 0 0 2 2 2 0 YqjK-like protein DUF3450 PF11932.8 OEU09466.1 - 3 7.1 14.3 0.53 9.5 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GTP_EFTU PF00009.27 OEU09467.1 - 1.1e-43 149.1 0.0 1.4e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OEU09467.1 - 4e-20 72.2 0.6 1.5e-19 70.3 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OEU09467.1 - 3.5e-12 46.5 0.1 1.2e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU09467.1 - 0.00037 20.6 0.0 0.0017 18.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 OEU09467.1 - 0.021 14.7 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 HEAT_2 PF13646.6 OEU09468.1 - 6.9e-07 29.6 2.8 0.00058 20.2 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 OEU09468.1 - 7.2e-06 25.8 7.5 0.12 12.6 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.20 OEU09468.1 - 0.008 14.8 0.9 0.13 10.8 0.9 2.4 1 1 0 1 1 1 1 Adaptin N terminal region Guanylate_cyc PF00211.20 OEU09468.1 - 0.045 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain BCL9 PF11502.8 OEU09468.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein MMS19_C PF12460.8 OEU09468.1 - 0.12 11.5 1.2 0.45 9.6 0.1 2.2 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal DUF5401 PF17380.2 OEU09468.1 - 0.5 8.4 17.8 1.5 6.8 18.4 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Gly_transf_sug PF04488.15 OEU09469.1 - 8.4e-10 39.2 0.4 3e-09 37.4 0.4 1.9 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OEU09469.1 - 1.3e-05 24.7 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 OEU09469.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF273 PF03314.14 OEU09470.1 - 9.4e-38 130.0 0.0 1.1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 OEU09470.1 - 0.0016 18.4 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 OEU09470.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Glycos_transf_1 PF00534.20 OEU09471.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Mito_carr PF00153.27 OEU09472.1 - 1.1e-43 147.1 0.3 1.9e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4148 PF13663.6 OEU09472.1 - 1.2 9.3 2.8 24 5.2 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4148) Helicase_C PF00271.31 OEU09473.1 - 1.1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OEU09473.1 - 7e-12 45.6 0.2 1.3e-11 44.8 0.2 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 OEU09473.1 - 4.1e-05 23.4 0.0 9.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 OEU09473.1 - 0.0027 17.4 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU09473.1 - 0.0053 17.0 0.4 0.031 14.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OEU09473.1 - 0.0066 17.0 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 OEU09473.1 - 0.091 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 OEU09473.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CHGN PF05679.16 OEU09475.1 - 2e-15 56.6 0.2 2.4e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Spin-Ssty PF02513.17 OEU09475.1 - 0.13 12.0 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Spin/Ssty Family CHGN PF05679.16 OEU09476.1 - 2.9e-12 46.2 0.2 2.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 OEU09476.1 - 2.1e-08 33.9 0.0 5.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OEU09476.1 - 2.2e-06 27.6 0.0 0.00038 20.3 0.0 3.3 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_7C PF02709.14 OEU09476.1 - 0.044 13.4 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase GMC_oxred_C PF05199.13 OEU09477.1 - 2.5e-16 60.5 0.0 5.1e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OEU09477.1 - 1.6e-11 44.1 0.1 9.6e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 GMC oxidoreductase YrvL PF14184.6 OEU09477.1 - 0.058 13.5 0.4 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 Regulatory protein YrvL CENP-B_dimeris PF09026.10 OEU09478.1 - 0.22 11.9 8.9 3.6 8.0 1.3 3.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain HEAT PF02985.22 OEU09478.1 - 0.55 10.6 2.5 76 4.0 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Microtub_bind PF13931.6 OEU09480.1 - 5.3 7.4 7.0 22 5.4 7.0 2.1 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding KHA PF11834.8 OEU09481.1 - 0.031 14.3 5.6 47 4.2 0.0 6.0 6 0 0 6 6 6 0 KHA, dimerisation domain of potassium ion channel ThiS-like PF14453.6 OEU09481.1 - 0.039 14.0 0.3 57 3.9 0.0 4.1 3 0 0 3 3 3 0 ThiS-like ubiquitin Clr2 PF10383.9 OEU09481.1 - 0.25 12.1 1.3 4.1 8.2 0.2 3.4 1 1 1 3 3 3 0 Transcription-silencing protein Clr2 GRA6 PF05084.13 OEU09482.1 - 0.001 19.1 1.9 0.41 10.6 0.2 2.3 2 0 0 2 2 2 2 Granule antigen protein (GRA6) DUF4834 PF16118.5 OEU09482.1 - 0.0054 17.7 0.4 0.63 11.0 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) Ammonium_transp PF00909.21 OEU09482.1 - 0.013 14.2 0.3 0.023 13.4 0.3 1.3 1 0 0 1 1 1 0 Ammonium Transporter Family Tetraspanin PF00335.20 OEU09482.1 - 0.31 10.7 7.6 1.8 8.2 0.0 3.2 2 1 1 3 3 3 0 Tetraspanin family Secretin_N_2 PF07655.13 OEU09482.1 - 3.6 8.2 9.8 1.9 9.1 0.7 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain AhpC-TSA_2 PF13911.6 OEU09483.1 - 2e-14 53.7 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ribosomal_L22e PF01776.17 OEU09484.1 - 5.9e-42 142.5 0.8 7.5e-42 142.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ABC2_membrane_4 PF12730.7 OEU09485.1 - 0.066 13.2 0.2 0.066 13.2 0.2 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Cg6151-P PF10233.9 OEU09485.1 - 0.47 10.8 5.8 0.1 12.9 1.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P Ribosomal_L24e PF01246.20 OEU09486.1 - 8.9e-22 77.1 0.0 2.3e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e HMGL-like PF00682.19 OEU09487.1 - 4.2e-84 282.2 0.0 7.2e-84 281.4 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OEU09487.1 - 1.5e-32 112.3 0.1 2.6e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain CLP_protease PF00574.23 OEU09488.1 - 1.2e-78 263.2 0.0 1.3e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease W2 PF02020.18 OEU09489.1 - 1.6e-10 41.0 4.7 3.6e-10 39.9 4.7 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon GRP PF07172.11 OEU09489.1 - 0.31 11.7 7.9 0.52 11.0 7.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family SKIP_SNW PF02731.15 OEU09490.1 - 5.6e-67 224.4 1.5 5.6e-67 224.4 1.5 2.3 2 0 0 2 2 2 1 SKIP/SNW domain DUF4407 PF14362.6 OEU09490.1 - 9.8 5.4 8.0 17 4.6 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNase_H2-Ydr279 PF09468.10 OEU09492.1 - 1.7e-07 31.6 0.5 3.9e-07 30.4 0.5 1.6 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OEU09492.1 - 0.0019 18.4 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DUF4281 PF14108.6 OEU09493.1 - 1.1e-32 113.1 2.2 1.3e-32 112.8 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DDDD PF10161.9 OEU09493.1 - 0.014 15.1 0.3 0.014 15.1 0.3 2.0 3 0 0 3 3 3 0 Putative mitochondrial precursor protein RNA_pol_Rpb2_6 PF00562.28 OEU09494.1 - 3.4e-117 391.8 0.0 5.4e-117 391.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OEU09494.1 - 2.6e-52 177.3 0.2 3.6e-52 176.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OEU09494.1 - 5.8e-32 110.0 0.1 1.4e-31 108.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OEU09494.1 - 4.2e-26 91.8 0.3 9.2e-26 90.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OEU09494.1 - 1.2e-22 79.9 0.4 3.5e-22 78.5 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OEU09494.1 - 3.7e-21 75.1 0.7 2.4e-20 72.5 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OEU09494.1 - 2.7e-14 53.4 0.1 7.4e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DAO PF01266.24 OEU09495.1 - 3.9e-27 95.8 0.0 4.6e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU09495.1 - 5.8e-07 29.6 0.1 1.7e-06 28.1 0.1 1.8 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU09495.1 - 1.5e-05 25.0 1.4 0.00013 22.0 0.1 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU09495.1 - 0.0027 17.0 0.0 0.011 15.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU09495.1 - 0.0035 16.6 0.0 0.0086 15.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OEU09495.1 - 0.0064 15.6 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 OEU09495.1 - 0.041 12.7 0.1 0.065 12.0 0.1 1.2 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 OEU09495.1 - 0.097 11.7 0.1 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein EF-hand_7 PF13499.6 OEU09496.1 - 1.1e-11 44.9 4.1 1.2e-11 44.8 4.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU09496.1 - 2.3e-10 39.3 6.7 3.2e-05 23.2 0.8 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU09496.1 - 1.6e-09 37.0 3.1 4.3e-05 23.1 0.4 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU09496.1 - 6.1e-07 28.7 8.0 0.0044 16.5 1.2 2.5 2 1 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 OEU09496.1 - 1.9e-05 24.9 0.1 2e-05 24.8 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 OEU09496.1 - 2.4e-05 24.1 8.2 0.00029 20.6 1.9 2.5 1 1 1 2 2 2 2 EF-hand domain pair RNA_pol_Rpb4 PF03874.16 OEU09496.1 - 0.026 14.9 0.4 0.029 14.7 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 EF-hand_4 PF12763.7 OEU09496.1 - 0.042 13.8 4.7 0.21 11.6 4.7 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Acetyltransf_1 PF00583.25 OEU09497.1 - 2.5e-15 56.7 0.0 2.7e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU09497.1 - 2e-09 37.5 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU09497.1 - 1.1e-06 29.0 0.0 1.4e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OEU09497.1 - 9.2e-05 22.6 0.1 0.00012 22.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU09497.1 - 0.00032 20.6 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein TFIIA_gamma_N PF02268.16 OEU09497.1 - 0.00091 19.2 0.2 0.3 11.1 0.0 2.3 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit, helical domain Acetyltransf_CG PF14542.6 OEU09497.1 - 0.018 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Nucleo_LEF-12 PF06256.11 OEU09497.1 - 0.025 14.3 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Myosin_head PF00063.21 OEU09498.1 - 2.2e-213 710.3 0.0 2.8e-213 709.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 OEU09498.1 - 0.0092 15.7 26.3 0.25 11.3 0.3 6.1 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_16 PF13191.6 OEU09498.1 - 0.049 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 OEU09498.1 - 0.054 12.8 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.12 OEU09498.1 - 0.1 12.1 0.2 10 5.6 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF1062 PF06353.12 OEU09499.1 - 0.00089 20.1 0.6 0.017 16.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1062) Spindle_Spc25 PF08234.12 OEU09500.1 - 3.4e-14 52.8 0.2 5.7e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Ist1 PF03398.14 OEU09501.1 - 6.6e-52 175.7 0.2 7.5e-52 175.6 0.2 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway F-112 PF09645.10 OEU09501.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 F-112 protein DUF4336 PF14234.6 OEU09503.1 - 6.6e-122 406.7 0.0 7.5e-122 406.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) RNase_PH PF01138.21 OEU09504.1 - 2.2e-19 70.3 0.1 7.5e-14 52.4 0.0 2.9 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OEU09504.1 - 4.5e-10 39.4 0.4 5.3e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 OEU09504.1 - 4e-08 33.5 0.4 4e-08 33.5 0.4 2.2 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 OEU09504.1 - 0.008 16.0 0.0 0.078 12.8 0.0 2.6 2 0 0 2 2 2 1 KH domain Cmc1 PF08583.10 OEU09505.1 - 2.2e-11 43.6 2.8 3.5e-11 43.0 2.8 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 OEU09505.1 - 0.057 13.9 3.9 0.099 13.1 3.9 1.6 1 1 0 1 1 1 0 GCK domain NDUF_B7 PF05676.13 OEU09505.1 - 0.23 11.2 3.9 0.17 11.6 2.5 1.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cytochrom_C1 PF02167.15 OEU09506.1 - 1.2e-91 306.3 0.0 1.5e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OEU09506.1 - 0.0025 18.1 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OEU09506.1 - 0.094 13.9 0.7 0.77 10.9 0.7 2.4 1 1 0 1 1 1 0 Cytochrome c Piwi PF02171.17 OEU09508.1 - 2e-10 40.4 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 OEU09508.1 - 1.1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF4183 PF13799.6 OEU09508.1 - 0.15 11.9 0.2 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) His_biosynth PF00977.21 OEU09509.1 - 1.5e-42 145.7 3.9 8.9e-41 139.8 3.8 3.6 1 1 1 2 2 2 1 Histidine biosynthesis protein GATase PF00117.28 OEU09509.1 - 3.8e-22 79.0 0.0 6.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OEU09509.1 - 2.8e-09 37.1 0.0 1.2e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OEU09509.1 - 9.7e-09 35.1 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 OEU09509.1 - 0.049 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Prok-RING_4 PF14447.6 OEU09510.1 - 9.3e-08 31.8 7.3 1.5e-07 31.1 7.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OEU09510.1 - 2.9e-07 30.2 6.3 4e-07 29.8 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU09510.1 - 2.6e-06 27.2 9.3 4.2e-06 26.5 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU09510.1 - 3.1e-06 27.4 9.3 4.9e-06 26.8 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU09510.1 - 1.1e-05 25.7 6.5 2.1e-05 24.7 6.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU09510.1 - 6.7e-05 22.8 2.7 6.7e-05 22.8 2.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU09510.1 - 9.3e-05 22.2 9.8 0.0002 21.1 9.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU09510.1 - 9.3e-05 22.3 8.6 0.00016 21.5 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OEU09510.1 - 0.005 16.9 2.4 0.0085 16.1 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OEU09510.1 - 0.0088 15.8 4.0 0.0088 15.8 4.0 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 OEU09510.1 - 0.017 15.2 1.2 0.017 15.2 1.2 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 OEU09510.1 - 0.065 12.6 0.2 0.065 12.6 0.2 1.9 1 1 0 2 2 2 0 Rtf2 RING-finger DHC PF09626.10 OEU09510.1 - 0.11 13.4 4.7 0.94 10.4 1.0 2.3 2 1 0 2 2 2 0 Dihaem cytochrome c Zn_ribbon_17 PF17120.5 OEU09510.1 - 0.13 11.9 5.9 0.69 9.6 6.1 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OEU09510.1 - 0.25 11.7 6.6 0.51 10.7 6.6 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 OEU09510.1 - 0.25 11.6 4.5 1.3 9.2 4.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PolC_DP2 PF03833.13 OEU09510.1 - 0.41 8.5 1.4 0.48 8.2 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Zn-ribbon_8 PF09723.10 OEU09510.1 - 0.42 10.8 4.7 4.2 7.6 1.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zf_RING PF16744.5 OEU09510.1 - 0.62 10.2 4.5 0.6 10.2 1.1 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 OEU09510.1 - 0.63 10.0 7.2 1.7 8.6 7.2 1.8 1 1 0 1 1 1 0 PHD-finger Cytochrome_C7 PF14522.6 OEU09510.1 - 5 7.2 12.0 1 9.4 8.4 1.9 2 1 0 2 2 1 0 Cytochrome c7 and related cytochrome c Homeobox_KN PF05920.11 OEU09511.1 - 3.3e-16 58.9 0.6 4.5e-16 58.5 0.6 1.2 1 1 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OEU09511.1 - 1.1e-06 28.4 0.2 1.2e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 Homeodomain zf-TAZ PF02135.16 OEU09512.1 - 1.6e-06 28.4 8.4 1.6e-06 28.4 8.4 1.9 2 0 0 2 2 2 1 TAZ zinc finger RNA_pol_Rpc34 PF05158.12 OEU09513.1 - 3.7e-51 174.5 4.2 8e-45 153.7 0.8 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 OEU09513.1 - 0.00029 21.0 0.1 0.00055 20.0 0.1 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC RPA_C PF08784.11 OEU09513.1 - 0.00084 20.0 0.6 1.1 9.9 0.1 2.3 2 1 0 2 2 2 2 Replication protein A C terminal MarR PF01047.22 OEU09513.1 - 0.032 14.2 0.2 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 MarR family DUF2250 PF10007.9 OEU09513.1 - 0.056 13.6 1.2 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Rrf2 PF02082.20 OEU09513.1 - 0.057 13.8 0.1 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator Cyclin_C PF02984.19 OEU09513.1 - 0.11 12.6 0.8 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain RRM_2 PF04059.12 OEU09514.1 - 1.3e-38 131.1 0.2 1.6e-38 130.7 0.2 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 OEU09514.1 - 1e-05 25.2 0.1 2.4e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 OEU09514.1 - 4.4e-05 23.6 0.1 5.1e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family BRAP2 PF07576.12 OEU09514.1 - 0.012 15.8 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 DAGK_cat PF00781.24 OEU09515.1 - 9.8e-21 73.7 0.0 1.6e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MitMem_reg PF13012.6 OEU09516.1 - 2.4e-18 66.6 0.1 4.9e-18 65.6 0.1 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OEU09516.1 - 7.8e-16 58.1 0.0 1.5e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3106 PF11304.8 OEU09517.1 - 0.038 14.5 2.5 0.038 14.5 2.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) UPF0184 PF03670.13 OEU09517.1 - 0.5 10.8 3.2 0.51 10.8 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Syntaxin-6_N PF09177.11 OEU09517.1 - 0.56 10.8 11.7 0.062 13.9 2.5 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal CENP-R PF06729.12 OEU09517.1 - 2.1 8.3 10.8 0.14 12.1 4.2 2.4 2 1 0 2 2 2 0 Kinetochore component, CENP-R HAD_2 PF13419.6 OEU09518.1 - 2.7e-07 30.8 0.0 5.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU09518.1 - 0.0004 20.7 0.0 0.00055 20.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU09518.1 - 0.006 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Unstab_antitox PF09720.10 OEU09518.1 - 0.074 13.1 0.2 0.23 11.5 0.2 1.9 1 1 0 1 1 1 0 Putative addiction module component LemA PF04011.12 OEU09518.1 - 0.12 12.2 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 LemA family CHCH PF06747.13 OEU09519.1 - 0.00016 21.7 5.9 0.00027 21.0 5.9 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 OEU09519.1 - 0.014 15.4 6.5 0.57 10.2 0.4 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pyrophosphatase PF00719.19 OEU09519.1 - 0.11 12.3 0.1 0.92 9.3 0.0 1.9 2 0 0 2 2 2 0 Inorganic pyrophosphatase Pet191_N PF10203.9 OEU09519.1 - 0.14 12.5 4.3 0.21 11.9 4.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 OEU09519.1 - 0.19 12.1 3.9 0.29 11.5 3.9 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) TFIID-31kDa PF02291.15 OEU09520.1 - 4.6e-15 55.8 0.1 9.2e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OEU09520.1 - 0.058 13.8 0.1 0.058 13.8 0.1 3.2 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 NAM-associated PF14303.6 OEU09520.1 - 0.35 11.6 14.5 0.027 15.2 4.5 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF4228 PF14009.6 OEU09520.1 - 3 8.2 9.7 6.8 7.0 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) EBP50_C PF09007.11 OEU09520.1 - 6.6 7.7 16.3 0.77 10.7 1.7 2.4 2 0 0 2 2 2 0 EBP50, C-terminal FUN14 PF04930.15 OEU09521.1 - 1.4e-22 79.9 1.4 1.7e-22 79.6 1.4 1.1 1 0 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 OEU09521.1 - 0.0048 16.3 3.3 0.027 13.9 0.2 2.5 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OEU09521.1 - 0.0097 15.4 0.1 0.0097 15.4 0.1 2.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OEU09521.1 - 0.044 13.7 1.4 0.11 12.5 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 OEU09521.1 - 0.11 12.9 0.3 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair Glyco_transf_22 PF03901.17 OEU09522.1 - 1e-50 173.2 26.8 1.6e-50 172.6 26.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aldo_ket_red PF00248.21 OEU09523.1 - 4.6e-51 173.7 0.0 6.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PPR_long PF17177.4 OEU09524.1 - 2.6e-10 40.1 0.4 1.3e-09 37.7 0.1 2.3 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 OEU09524.1 - 2.9e-10 40.2 1.4 0.0075 16.4 0.0 5.6 3 2 2 5 5 5 4 PPR repeat family PPR_3 PF13812.6 OEU09524.1 - 0.0014 18.6 0.6 0.13 12.4 0.0 3.5 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 OEU09524.1 - 0.0016 18.6 1.9 5.5 7.5 0.1 4.8 5 0 0 5 5 5 1 PPR repeat Methyltransf_23 PF13489.6 OEU09525.1 - 3e-06 27.2 0.0 1.2e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU09525.1 - 0.00024 21.8 0.0 0.00044 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU09525.1 - 0.00027 20.8 0.9 0.0013 18.5 0.9 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU09525.1 - 0.0003 21.5 2.4 0.00074 20.2 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 OEU09525.1 - 0.0099 15.7 0.1 0.16 11.7 0.0 2.4 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OEU09525.1 - 0.021 14.4 0.1 0.061 12.9 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 OEU09525.1 - 0.047 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 OEU09525.1 - 0.052 12.9 0.6 8.4 5.7 0.0 2.6 2 1 1 3 3 3 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 OEU09525.1 - 0.21 11.6 1.5 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_3 PF13302.7 OEU09526.1 - 1.6e-23 83.9 0.0 1.2e-22 81.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU09526.1 - 0.00062 20.0 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OEU09526.1 - 0.00066 19.4 0.1 1.3 8.7 0.3 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU09526.1 - 0.0093 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 OEU09526.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_phi PF04931.13 OEU09526.1 - 1.4 6.9 12.1 1.8 6.5 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Guanylate_kin PF00625.21 OEU09527.1 - 7.4e-56 188.7 0.0 9.2e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 OEU09527.1 - 2.9e-05 24.6 0.4 0.00014 22.4 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU09527.1 - 0.00018 21.7 0.0 0.0024 18.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OEU09527.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 OEU09527.1 - 0.00038 20.5 0.0 0.00061 19.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OEU09527.1 - 0.0046 16.5 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OEU09527.1 - 0.0053 17.2 0.0 0.0089 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 OEU09527.1 - 0.0066 16.2 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 OEU09527.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OEU09527.1 - 0.02 15.3 0.1 0.082 13.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU09527.1 - 0.037 14.0 0.0 0.097 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OEU09527.1 - 0.051 14.1 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 OEU09527.1 - 0.056 13.8 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 OEU09527.1 - 0.073 13.3 0.1 0.29 11.4 0.0 2.1 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 OEU09527.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Glyco_trans_1_4 PF13692.6 OEU09528.1 - 1e-08 35.7 0.0 2.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OEU09528.1 - 5.1e-07 29.4 0.0 1.5e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OEU09528.1 - 0.00062 20.1 0.0 0.0023 18.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_22 PF03901.17 OEU09530.1 - 2.4e-52 178.6 17.9 6.5e-49 167.3 13.8 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Ribosomal_S17e PF00833.18 OEU09531.1 - 5.6e-59 197.4 0.0 6.2e-59 197.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 adh_short PF00106.25 OEU09532.1 - 2.4e-17 63.1 0.0 4.1e-10 39.4 0.1 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU09532.1 - 3.1e-07 30.2 0.0 0.0042 16.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase GvpL_GvpF PF06386.11 OEU09532.1 - 0.23 11.3 0.1 0.36 10.7 0.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Stc1 PF12898.7 OEU09533.1 - 8.9e-06 26.2 37.5 0.003 18.1 3.5 3.5 2 1 1 3 3 3 3 Stc1 domain Hydin_ADK PF17213.3 OEU09533.1 - 0.56 10.5 10.0 0.97 9.7 10.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Exonuc_VII_L PF02601.15 OEU09533.1 - 0.85 9.1 7.6 1.2 8.6 7.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BORG_CEP PF14957.6 OEU09533.1 - 1.6 9.9 6.0 3.9 8.6 6.0 1.7 1 0 0 1 1 1 0 Cdc42 effector Cellulose_synt PF03552.14 OEU09533.1 - 5.3 5.4 6.3 7.3 4.9 6.3 1.1 1 0 0 1 1 1 0 Cellulose synthase EMC3_TMCO1 PF01956.16 OEU09533.1 - 7 6.3 9.5 14 5.4 9.5 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MIF4G_like_2 PF09090.11 OEU09535.1 - 0.053 13.0 2.2 0.069 12.6 0.1 2.0 1 1 1 2 2 2 0 MIF4G like DUF3510 PF12022.8 OEU09536.1 - 3.9e-24 85.4 0.0 5.2e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) EIN3 PF04873.13 OEU09536.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Ethylene insensitive 3 PEPcase_2 PF14010.6 OEU09536.1 - 0.047 12.2 0.0 0.047 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF4131 PF13567.6 OEU09537.1 - 1.5 8.4 0.0 1.5 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ras PF00071.22 OEU09538.1 - 3.6e-63 212.0 0.3 4.2e-63 211.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU09538.1 - 1.1e-35 122.5 0.1 1.7e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU09538.1 - 1.2e-16 60.7 0.0 1.4e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU09538.1 - 4.3e-07 30.0 0.0 3.6e-06 27.1 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OEU09538.1 - 1.2e-06 28.1 0.1 1.4e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OEU09538.1 - 3e-06 26.9 0.5 7.3e-06 25.7 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OEU09538.1 - 3.2e-05 23.4 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OEU09538.1 - 0.00027 20.9 0.2 0.087 12.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OEU09538.1 - 0.00035 20.1 0.0 0.0029 17.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 OEU09538.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OEU09538.1 - 0.024 15.0 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OEU09538.1 - 0.036 13.2 1.3 0.19 10.9 0.4 1.9 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 OEU09538.1 - 0.063 13.8 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OEU09538.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 OEU09538.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CENP-M PF11111.8 OEU09538.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Pyr_redox_2 PF07992.14 OEU09539.1 - 1.1e-70 238.2 3.6 1.5e-70 237.8 3.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU09539.1 - 8.7e-42 141.8 1.2 1.1e-41 141.5 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU09539.1 - 3.5e-23 81.9 5.3 1e-19 70.9 0.5 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU09539.1 - 6.3e-10 39.0 0.4 1.6e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OEU09539.1 - 2.3e-09 36.8 0.5 5.4e-07 29.0 0.2 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OEU09539.1 - 2.2e-07 30.5 2.6 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU09539.1 - 3e-07 30.5 4.2 0.00013 22.2 0.4 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OEU09539.1 - 6.4e-07 28.9 2.5 0.0007 19.0 0.4 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OEU09539.1 - 1.8e-05 24.0 8.7 1.9e-05 23.9 1.7 3.0 3 1 1 4 4 4 1 FAD binding domain Thi4 PF01946.17 OEU09539.1 - 0.00041 19.7 0.6 0.0016 17.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OEU09539.1 - 0.0026 17.1 8.0 0.028 13.7 0.7 2.4 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 OEU09539.1 - 0.006 15.8 0.2 1.3 8.1 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OEU09539.1 - 0.0063 15.6 0.1 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OEU09539.1 - 0.012 14.3 1.1 0.012 14.3 1.1 3.3 3 1 1 4 4 4 0 HI0933-like protein 3HCDH_N PF02737.18 OEU09539.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PASTA PF03793.19 OEU09539.1 - 0.02 14.7 1.4 0.1 12.5 0.3 2.6 2 0 0 2 2 2 0 PASTA domain DAO PF01266.24 OEU09539.1 - 0.63 9.6 8.7 3.4 7.2 0.2 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OEU09539.1 - 8.5 6.9 6.4 5.9 7.4 0.9 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding RPN2_C PF18004.1 OEU09540.1 - 1.7e-37 128.8 9.6 1.7e-37 128.8 9.6 2.4 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OEU09540.1 - 6.8e-27 92.5 24.9 1.1e-05 25.6 0.1 8.2 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OEU09540.1 - 7.3e-16 58.3 6.9 1.8e-10 41.0 0.0 5.3 3 2 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 OEU09540.1 - 0.0087 16.5 0.1 0.58 10.7 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 OEU09540.1 - 0.011 16.0 0.5 19 5.9 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat Adaptin_N PF01602.20 OEU09540.1 - 0.011 14.3 0.7 27 3.1 0.0 4.7 5 1 0 5 5 5 0 Adaptin N terminal region IPK PF03770.16 OEU09541.1 - 4.7e-41 140.8 0.0 7.3e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Hexapep PF00132.24 OEU09543.1 - 0.8 9.5 25.6 3.3 7.6 4.1 5.6 3 1 2 5 5 5 0 Bacterial transferase hexapeptide (six repeats) FAA_hydrolase PF01557.18 OEU09543.1 - 6.4 6.4 6.1 31 4.1 1.3 2.3 1 1 1 2 2 2 0 Fumarylacetoacetate (FAA) hydrolase family DUF2076 PF09849.9 OEU09545.1 - 0.55 10.2 4.5 0.58 10.2 4.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) cwf18 PF08315.12 OEU09546.1 - 2.4e-25 89.8 14.7 5.2e-24 85.4 14.7 2.0 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor Aspzincin_M35 PF14521.6 OEU09546.1 - 0.0021 18.6 0.6 0.0036 17.9 0.6 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF2236 PF09995.9 OEU09549.1 - 1.6e-21 77.6 0.0 2.9e-21 76.7 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Rab5ip PF07019.12 OEU09550.1 - 1.7 9.3 5.6 5.2 7.7 5.6 1.8 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) CRT-like PF08627.10 OEU09551.1 - 2.7e-15 56.2 14.1 9.3e-12 44.5 3.7 2.6 2 1 1 3 3 3 2 CRT-like, chloroquine-resistance transporter-like Herpes_UL49_5 PF05702.11 OEU09551.1 - 0.075 13.1 0.5 0.36 11.0 0.2 2.4 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein SAPS PF04499.15 OEU09552.1 - 9.5e-06 24.7 4.1 9.5e-06 24.7 4.1 5.3 2 1 1 4 4 4 2 SIT4 phosphatase-associated protein TbpB_A PF17484.2 OEU09552.1 - 6.3 7.6 8.1 0.51 11.1 1.8 2.5 2 0 0 2 2 2 0 N-Lobe handle Tf-binding protein B Fe-S_biosyn PF01521.20 OEU09553.1 - 1.5e-16 60.6 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Lung_7-TM_R PF06814.13 OEU09556.1 - 4.5e-40 137.7 14.0 5.2e-40 137.5 14.0 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1700 PF08006.11 OEU09556.1 - 0.24 10.9 11.2 0.02 14.5 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Phage_holin_5_2 PF16079.5 OEU09556.1 - 0.6 10.5 6.3 0.21 12.0 1.1 2.7 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Methyltransf_16 PF10294.9 OEU09557.1 - 1.4e-15 57.5 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OEU09557.1 - 0.0025 18.5 0.1 0.0074 17.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU09557.1 - 0.0083 16.8 0.1 0.044 14.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 OEU09557.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 OEU09557.1 - 0.08 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OEU09557.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain VASt PF16016.5 OEU09558.1 - 2.9e-22 79.7 1.3 4.1e-22 79.2 1.3 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DivIC PF04977.15 OEU09558.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator GSDH PF07995.11 OEU09559.1 - 2e-38 132.6 0.1 5e-38 131.2 0.0 1.6 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU09559.1 - 3.6e-12 45.9 1.6 1.6e-10 40.7 0.3 2.5 2 0 0 2 2 2 1 PKD domain REJ PF02010.15 OEU09559.1 - 0.0008 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 REJ domain CDC45 PF02724.14 OEU09559.1 - 1.7 6.9 8.0 2.9 6.1 8.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OEU09559.1 - 1.7 7.1 3.8 3.2 6.2 3.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LSM PF01423.22 OEU09560.1 - 6.7e-14 51.3 0.0 8e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OEU09560.1 - 0.00086 19.4 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain TamB PF04357.13 OEU09560.1 - 0.043 13.0 0.0 0.053 12.8 0.0 1.0 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex LSM14 PF12701.7 OEU09560.1 - 0.095 12.8 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain RNA_pol_Rpb5_C PF01191.19 OEU09561.1 - 9.8e-34 115.1 0.4 1.7e-33 114.3 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OEU09561.1 - 6.2e-25 87.6 0.1 1e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF3235 PF11574.8 OEU09561.1 - 0.15 12.9 0.0 0.42 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) ketoacyl-synt PF00109.26 OEU09562.1 - 1.9e-49 168.6 0.3 1.9e-49 168.6 0.3 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OEU09562.1 - 6.5e-35 119.7 1.8 6.5e-35 119.7 1.8 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 OEU09562.1 - 1.9e-05 24.2 1.1 3.6e-05 23.3 0.5 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 OEU09562.1 - 0.0059 16.4 0.3 0.37 10.7 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CBS PF00571.28 OEU09563.1 - 5.1e-09 36.5 1.8 9.5e-05 22.8 0.7 2.5 2 0 0 2 2 2 2 CBS domain NAD_binding_10 PF13460.6 OEU09563.1 - 0.054 13.4 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding MmoB_DmpM PF02406.17 OEU09563.1 - 0.11 12.8 1.0 0.2 11.9 1.0 1.5 1 0 0 1 1 1 0 MmoB/DmpM family CitMHS PF03600.16 OEU09564.1 - 1.4e-34 119.7 8.1 1.4e-34 119.7 8.1 1.4 1 1 0 1 1 1 1 Citrate transporter HA PF03457.14 OEU09565.1 - 3.6e-95 312.3 41.3 9.5e-17 61.1 0.7 6.0 6 0 0 6 6 6 6 Helicase associated domain ELL PF10390.9 OEU09565.1 - 0.00095 18.7 0.0 3.2 7.2 0.0 3.2 3 0 0 3 3 3 2 RNA polymerase II elongation factor ELL DUF3836 PF12930.7 OEU09565.1 - 0.0027 17.4 16.9 0.55 10.0 0.5 5.3 5 1 1 6 6 6 3 Family of unknown function (DUF3836) Phosphoesterase PF04185.14 OEU09565.1 - 0.2 10.8 8.7 4.9 6.2 0.1 4.0 2 1 3 5 5 5 0 Phosphoesterase family Lentiviral_Tat PF02998.14 OEU09565.1 - 0.67 10.0 16.9 2.4 8.2 0.0 5.5 4 2 1 5 5 5 0 Lentiviral Tat protein Prenyltrans PF00432.21 OEU09566.1 - 2e-56 187.3 14.1 4.9e-12 45.4 0.2 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OEU09566.1 - 3.2e-06 26.5 0.0 6.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain DUF2314 PF10077.9 OEU09566.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) PH PF00169.29 OEU09567.1 - 0.00027 21.4 0.0 0.00052 20.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PRA1 PF03208.19 OEU09568.1 - 9.5e-15 54.5 7.1 1.8e-14 53.5 7.1 1.5 1 1 0 1 1 1 1 PRA1 family protein YqjK PF13997.6 OEU09568.1 - 0.81 10.0 2.6 1.4 9.2 0.2 2.1 2 0 0 2 2 2 0 YqjK-like protein PCI PF01399.27 OEU09570.1 - 5.3e-15 55.8 0.1 1e-14 54.9 0.1 1.5 1 0 0 1 1 1 1 PCI domain Tox-REase-2 PF15646.6 OEU09570.1 - 0.05 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 TetR_C_36 PF18598.1 OEU09570.1 - 0.094 12.7 0.6 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_19 PF14559.6 OEU09570.1 - 0.1 13.1 0.8 2.3 8.8 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2499 PF10693.9 OEU09571.1 - 1.7e-31 108.3 5.5 1.8e-31 108.2 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 OEU09572.1 - 2.8e-30 104.2 0.5 3.1e-30 104.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) DUF5379 PF17350.2 OEU09572.1 - 0.079 13.2 0.3 0.09 13.1 0.3 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5379) DUF1499 PF07386.11 OEU09573.1 - 1.9e-22 80.0 0.0 2.5e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) PX PF00787.24 OEU09575.1 - 4.4e-06 26.6 0.0 7.7e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 PX domain DUF2388 PF09498.10 OEU09575.1 - 0.003 17.5 0.3 0.015 15.2 0.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) Myosin_head PF00063.21 OEU09578.1 - 1.3e-196 654.9 2.2 1.1e-177 592.3 0.1 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_19 PF13245.6 OEU09578.1 - 0.0022 18.3 0.0 0.0049 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OEU09578.1 - 0.044 14.2 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 RNA helicase CBS PF00571.28 OEU09579.1 - 8.7e-31 106.2 9.7 4.8e-10 39.7 0.1 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 OEU09579.1 - 4.8e-06 26.4 0.0 9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PLA2G12 PF06951.11 OEU09580.1 - 5.6e-09 36.2 18.7 1.2e-08 35.0 18.7 1.6 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) PocR PF10114.9 OEU09581.1 - 0.0021 17.8 6.5 2.4 7.9 0.3 3.5 3 0 0 3 3 3 3 Sensory domain found in PocR Orf78 PF06024.12 OEU09581.1 - 0.0052 17.1 0.0 0.0052 17.1 0.0 2.7 3 1 0 3 3 3 1 Orf78 (ac78) DUF3572 PF12096.8 OEU09581.1 - 0.011 15.9 1.6 0.21 11.8 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3572) pXO2-34 PF17362.2 OEU09581.1 - 0.035 14.0 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function Skp1 PF01466.19 OEU09581.1 - 0.053 13.6 8.0 3.4 7.9 0.0 5.4 4 3 2 6 6 6 0 Skp1 family, dimerisation domain DUF1877 PF08974.10 OEU09581.1 - 0.16 12.1 3.3 8.8 6.4 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1877) AIM5 PF17050.5 OEU09581.1 - 0.31 11.9 3.5 54 4.7 0.1 3.7 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 TraE PF05309.11 OEU09581.1 - 0.66 9.3 8.8 0.065 12.6 1.1 2.7 3 0 0 3 3 3 0 TraE protein zf-CCCH_6 PF18585.1 OEU09581.1 - 0.78 9.7 6.1 0.43 10.5 0.4 3.3 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF1829 PF08862.10 OEU09581.1 - 0.85 10.2 2.8 1.7 9.1 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF1829 DUF1798 PF08807.10 OEU09581.1 - 5.4 7.2 6.8 40 4.4 0.5 3.5 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) NMO PF03060.15 OEU09582.1 - 2.6e-55 188.1 2.7 7.7e-53 180.0 2.7 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OEU09582.1 - 3.3e-13 49.4 0.9 3.3e-12 46.1 0.9 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OEU09582.1 - 1.9e-09 37.1 4.4 3.8e-09 36.1 4.6 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 OEU09582.1 - 9.1e-05 21.9 3.0 0.00018 20.9 3.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Lactamase_B_5 PF14597.6 OEU09582.1 - 0.021 14.3 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily His_biosynth PF00977.21 OEU09582.1 - 0.059 12.8 0.4 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein His_Phos_1 PF00300.22 OEU09583.1 - 2.7e-20 72.9 0.1 3.7e-11 43.1 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pyridox_oxase_2 PF12766.7 OEU09584.1 - 1.5e-26 93.0 0.0 2.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 OEU09584.1 - 0.00027 21.0 0.0 0.0012 19.0 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase JmjC PF02373.22 OEU09585.1 - 4.7e-19 68.9 0.1 1.2e-18 67.6 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OEU09585.1 - 1.1e-14 54.8 1.4 2e-14 53.9 0.1 2.1 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 OEU09585.1 - 0.028 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain dTDP_sugar_isom PF00908.17 OEU09585.1 - 0.053 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Cupin_1 PF00190.22 OEU09585.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin GPI PF06560.11 OEU09585.1 - 0.15 11.4 0.0 0.44 9.8 0.0 1.8 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) CIA30 PF08547.12 OEU09586.1 - 3.2e-17 63.0 0.1 4.5e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SMC_N PF02463.19 OEU09587.1 - 5.3e-58 196.0 11.1 3.5e-57 193.4 11.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OEU09587.1 - 1.3e-25 90.0 0.8 3.4e-25 88.6 0.1 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OEU09587.1 - 2.6e-13 50.9 7.2 2.6e-13 50.9 7.2 7.9 3 3 1 4 4 4 1 AAA domain AAA_15 PF13175.6 OEU09587.1 - 1.5e-10 41.3 0.0 1.5e-10 41.3 0.0 5.5 2 2 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 OEU09587.1 - 3.6e-08 33.6 10.9 9.2e-06 25.7 0.1 4.2 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OEU09587.1 - 3.2e-06 26.8 0.1 1.3e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 OEU09587.1 - 0.019 15.2 0.2 0.16 12.2 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 OEU09587.1 - 9.5 6.5 8.5 10 6.4 0.0 4.6 5 0 0 5 5 5 0 AAA domain IF4E PF01652.18 OEU09588.1 - 6.8e-50 169.0 0.0 1.2e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpp10 PF04006.12 OEU09589.1 - 2.9e-88 296.9 17.6 3.7e-88 296.5 17.6 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF4599 PF15371.6 OEU09589.1 - 0.43 11.2 4.1 0.46 11.0 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) S-methyl_trans PF02574.16 OEU09590.1 - 3e-28 99.4 0.0 3.5e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DAHP_snth_FXD PF18152.1 OEU09590.1 - 0.049 13.5 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain DNA_primase_lrg PF04104.14 OEU09591.1 - 0.29 10.5 4.6 2.8 7.2 0.4 2.7 1 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit CDP-OH_P_transf PF01066.21 OEU09593.1 - 1.1e-15 58.1 2.7 1.8e-15 57.4 0.0 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Myosin_head PF00063.21 OEU09594.1 - 8.6e-217 721.6 1.3 1e-216 721.3 1.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 OEU09594.1 - 2.7e-12 45.3 31.7 0.054 13.3 0.2 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif T2SSE PF00437.20 OEU09594.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 OEU09594.1 - 0.0019 18.6 0.1 0.01 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OEU09594.1 - 0.013 15.8 0.0 0.055 13.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU09594.1 - 0.018 15.4 0.1 0.2 12.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 OEU09594.1 - 0.031 14.8 0.1 0.091 13.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 OEU09594.1 - 0.066 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 OEU09594.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PYRIN PF02758.16 OEU09594.1 - 0.08 13.1 0.2 0.35 11.1 0.2 2.1 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Sigma54_activat PF00158.26 OEU09594.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain FYVE PF01363.21 OEU09595.1 - 3.8e-06 26.9 12.8 7e-06 26.1 12.8 1.5 1 1 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 OEU09595.1 - 0.0025 18.0 5.2 0.0025 18.0 5.2 1.8 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 OEU09595.1 - 0.0025 18.0 4.8 0.0034 17.6 4.8 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger zf-UBP PF02148.19 OEU09595.1 - 0.71 10.2 12.7 4.2 7.8 0.3 2.3 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ammonium_transp PF00909.21 OEU09596.1 - 5.7e-104 348.0 24.0 7.2e-104 347.6 24.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RPN1_RPN2_N PF17781.1 OEU09597.1 - 2e-103 346.1 3.6 3.4e-103 345.3 3.6 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OEU09597.1 - 6.7e-29 99.7 0.1 1.3e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OEU09597.1 - 6.7e-22 76.7 13.9 4.2e-06 26.9 0.0 7.7 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OEU09597.1 - 0.00092 19.6 0.6 6.5 7.2 0.0 4.2 2 1 2 5 5 5 2 HEAT repeats TPR_15 PF13429.6 OEU09597.1 - 0.037 13.3 0.2 0.084 12.1 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Sec7 PF01369.20 OEU09598.1 - 9.4e-54 181.9 0.0 1.6e-52 177.8 0.0 2.6 3 0 0 3 3 3 1 Sec7 domain PhyH PF05721.13 OEU09599.1 - 1.7e-15 57.8 0.4 2.8e-15 57.1 0.4 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OEU09599.1 - 0.017 13.9 0.4 0.52 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) CLPTM1 PF05602.12 OEU09600.1 - 3.9e-44 151.4 2.9 4.9e-44 151.0 2.9 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OEU09600.1 - 0.00041 20.1 8.7 0.02 14.6 0.2 3.7 2 1 1 3 3 3 3 PQ loop repeat SR-25 PF10500.9 OEU09601.1 - 0.016 14.9 4.9 0.019 14.6 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 OEU09604.1 - 7.1e-18 64.6 0.1 9.7e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU09604.1 - 0.046 13.4 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF5082 PF16888.5 OEU09605.1 - 0.0078 16.5 1.1 0.0078 16.5 1.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) DUF848 PF05852.11 OEU09605.1 - 1.9 8.6 6.8 0.65 10.1 3.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 OEU09605.1 - 3.5 6.9 11.5 3.4 6.9 8.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CybS PF05328.12 OEU09606.1 - 1.9e-05 24.4 0.0 2.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit PseudoU_synth_2 PF00849.22 OEU09607.1 - 1.7e-25 90.0 0.0 3.1e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Molydop_binding PF01568.21 OEU09607.1 - 0.058 13.4 0.4 0.34 11.0 0.0 2.4 4 0 0 4 4 4 0 Molydopterin dinucleotide binding domain ThiF PF00899.21 OEU09608.1 - 7e-63 212.2 0.0 1e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OEU09608.1 - 1.1e-08 35.5 0.0 2.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 OEU09608.1 - 0.00044 20.5 1.1 0.0022 18.3 1.1 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OEU09608.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OEU09608.1 - 0.028 14.0 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IL6Ra-bind PF09240.10 OEU09608.1 - 0.079 13.4 0.6 0.23 11.9 0.6 1.8 1 1 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding TrkA_N PF02254.18 OEU09608.1 - 0.086 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 OEU09608.1 - 0.16 11.3 0.5 0.62 9.4 0.2 1.8 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PGA_cap PF09587.10 OEU09609.1 - 4.4e-42 144.3 0.0 6.4e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap UPF0114 PF03350.16 OEU09609.1 - 0.022 15.0 0.7 0.76 10.0 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 DUF3810 PF12725.7 OEU09609.1 - 0.12 11.7 0.3 0.19 11.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PUF PF00806.19 OEU09610.1 - 4.7e-57 186.6 13.1 3.4e-08 32.7 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OEU09610.1 - 0.0088 16.4 2.3 1.8 8.9 0.1 3.9 2 1 3 5 5 5 2 CPL (NUC119) domain Glyco_hydro_80 PF13647.6 OEU09610.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 80 of chitosanase A MA3 PF02847.17 OEU09610.1 - 0.23 11.5 1.7 4.8 7.2 0.5 3.0 2 1 0 2 2 2 0 MA3 domain TRIC PF05197.13 OEU09611.1 - 5.7e-07 29.3 0.6 7.4e-07 28.9 0.6 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 OEU09611.1 - 0.072 13.0 0.6 0.072 13.0 0.6 2.2 2 0 0 2 2 2 0 UPF0126 domain Lipase_3 PF01764.25 OEU09612.1 - 2.4e-18 66.4 0.0 5.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OEU09612.1 - 0.0022 17.6 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 OEU09612.1 - 0.0034 18.0 0.0 0.07 13.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 OEU09612.1 - 0.0052 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OEU09612.1 - 0.017 14.9 0.2 0.046 13.4 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_3 PF07859.13 OEU09612.1 - 0.032 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNase_H PF00075.24 OEU09612.1 - 0.045 13.9 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 RNase H LIDHydrolase PF10230.9 OEU09612.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Bromodomain PF00439.25 OEU09614.1 - 2.6e-19 69.1 0.0 3.1e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 OEU09615.1 - 4.5e-17 61.9 0.1 4.8e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Bromodomain SNF2_N PF00176.23 OEU09616.1 - 3.8e-50 170.6 0.0 9.2e-50 169.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU09616.1 - 5.9e-21 74.9 0.0 4.7e-20 72.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 OEU09616.1 - 4.2e-07 29.8 0.1 1.5e-06 28.0 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 OEU09616.1 - 3e-06 26.6 0.1 0.00062 19.0 0.0 3.1 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OEU09616.1 - 6.3e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU09616.1 - 0.00026 20.8 0.0 0.00088 19.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OEU09616.1 - 0.0034 16.6 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 OEU09616.1 - 0.03 13.6 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP_N PF12457.8 OEU09616.1 - 0.039 14.3 2.3 0.24 11.8 0.4 2.8 2 1 0 2 2 2 0 Tuftelin interacting protein N terminal Bromodomain PF00439.25 OEU09617.1 - 1.1e-21 76.7 0.0 1.2e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Bromodomain CHU_C PF13585.6 OEU09617.1 - 0.052 13.6 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family HMG_box PF00505.19 OEU09618.1 - 3.5e-11 43.3 0.0 4.3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU09618.1 - 6e-05 23.6 0.0 6.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OEU09618.1 - 0.00088 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain DENN PF02141.21 OEU09619.1 - 4.4e-45 153.9 6.9 7.9e-45 153.1 6.9 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OEU09619.1 - 2.1e-17 63.6 0.4 7.8e-17 61.8 0.4 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OEU09619.1 - 2.5e-06 27.4 4.3 1.2e-05 25.2 4.3 2.3 1 0 0 1 1 1 1 dDENN domain PPR PF01535.20 OEU09619.1 - 0.00018 21.5 0.2 0.00061 19.9 0.1 2.0 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 OEU09619.1 - 0.00061 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 OEU09619.1 - 0.0031 17.7 0.0 0.11 12.7 0.0 2.4 1 1 1 2 2 2 2 PPR repeat family Lin-8 PF03353.15 OEU09620.1 - 1.6 8.2 6.5 2.1 7.8 3.7 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Sua5_yciO_yrdC PF01300.18 OEU09621.1 - 4.3e-38 130.6 0.0 7.3e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OEU09621.1 - 1.6e-12 48.1 0.0 3.1e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding GTP_EFTU PF00009.27 OEU09622.1 - 8.7e-59 198.3 0.0 1.6e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OEU09622.1 - 7e-34 116.2 0.3 2.7e-33 114.3 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 OEU09622.1 - 8.6e-31 105.9 0.2 2.9e-30 104.2 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 OEU09622.1 - 1.1e-25 89.4 0.1 5.8e-25 87.2 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OEU09622.1 - 2.6e-10 40.6 0.1 7.4e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OEU09622.1 - 2.1e-09 37.3 0.0 5.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OEU09622.1 - 0.0017 18.4 0.0 0.0051 16.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OEU09622.1 - 0.013 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FolB PF02152.18 OEU09622.1 - 0.041 14.4 0.2 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Dihydroneopterin aldolase zf-C3HC4_3 PF13920.6 OEU09623.1 - 1.5e-08 34.3 18.9 1.5e-08 34.3 18.9 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 OEU09623.1 - 4.4e-05 24.0 0.2 0.025 15.1 0.0 2.6 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU09623.1 - 0.00051 20.3 0.1 0.0041 17.5 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OEU09623.1 - 0.0023 18.2 0.4 0.03 14.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU09623.1 - 0.0032 18.0 0.0 0.0074 16.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Prok-RING_4 PF14447.6 OEU09623.1 - 0.0047 16.8 17.7 0.0047 16.8 17.7 3.6 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 Ank PF00023.30 OEU09623.1 - 0.013 16.0 0.1 0.094 13.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat HAV_VP PF12944.7 OEU09623.1 - 0.041 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP Delta_lysin PF05372.11 OEU09623.1 - 0.38 10.1 1.1 0.89 8.9 1.1 1.5 1 0 0 1 1 1 0 Delta lysin family Pkinase PF00069.25 OEU09624.1 - 4.4e-38 131.2 0.0 5e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09624.1 - 3e-18 66.1 0.0 5.9e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU09624.1 - 7.9e-06 24.9 0.0 1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU09624.1 - 0.003 17.5 0.1 0.16 11.9 0.3 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OEU09624.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OEU09624.1 - 0.032 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE PF01363.21 OEU09625.1 - 6.4e-09 35.8 14.6 6.4e-09 35.8 14.6 2.6 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 OEU09625.1 - 8.6e-09 35.1 14.0 8.6e-09 35.1 14.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 OEU09625.1 - 0.00024 21.6 0.0 1.3 9.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU09625.1 - 0.0016 19.0 0.0 0.0046 17.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU09625.1 - 0.009 16.5 0.0 0.21 12.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Zea_mays_MuDR PF05928.11 OEU09626.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Hamartin PF04388.12 OEU09626.1 - 9.7 4.7 20.5 13 4.3 20.5 1.1 1 0 0 1 1 1 0 Hamartin protein Prefoldin PF02996.17 OEU09628.1 - 8.8e-26 90.2 1.4 1.1e-25 89.8 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 OEU09628.1 - 0.94 10.1 5.7 9.6 6.9 0.5 2.2 2 0 0 2 2 2 0 SlyX CK_II_beta PF01214.18 OEU09629.1 - 5.7e-80 267.4 0.1 7e-80 267.1 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Zn_Tnp_IS1 PF03811.13 OEU09629.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 InsA N-terminal domain GTP_EFTU PF00009.27 OEU09630.1 - 6.2e-67 224.9 0.0 1.2e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OEU09630.1 - 2e-40 137.3 0.2 3.9e-40 136.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 OEU09630.1 - 1.1e-34 118.3 0.1 2.6e-34 117.1 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OEU09630.1 - 4.3e-25 87.6 0.0 1.2e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OEU09630.1 - 3.7e-14 52.9 4.0 4.8e-14 52.5 0.4 2.9 4 0 0 4 4 4 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OEU09630.1 - 6.2e-07 29.3 0.1 1.3e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OEU09630.1 - 0.00041 20.4 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 OEU09630.1 - 0.052 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family HTH_Tnp_Tc5 PF03221.16 OEU09630.1 - 0.1 12.6 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain NopRA1 PF16201.5 OEU09632.1 - 3.9e-37 127.8 0.4 3.9e-37 127.8 0.4 3.2 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 ThiF PF00899.21 OEU09632.1 - 0.045 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family Kinesin PF00225.23 OEU09633.1 - 9.7e-100 333.7 0.5 9.7e-100 333.7 0.5 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OEU09633.1 - 5.9e-32 110.7 7.1 6.2e-29 100.9 0.3 3.6 2 1 1 3 3 3 2 Microtubule binding AAA_22 PF13401.6 OEU09633.1 - 0.02 15.2 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain HAUS-augmin3 PF14932.6 OEU09633.1 - 1.7 8.1 29.9 0.27 10.8 12.1 2.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 YscO-like PF16789.5 OEU09633.1 - 2.7 8.0 26.6 7.2 6.6 26.6 1.7 1 0 0 1 1 1 0 YscO-like protein BRE1 PF08647.11 OEU09633.1 - 6.7 6.9 32.5 1.4 9.1 6.7 3.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Lung_7-TM_R PF06814.13 OEU09634.1 - 9e-51 172.9 12.9 1e-50 172.7 12.9 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 OEU09634.1 - 4.4e-05 23.0 15.5 6.8e-05 22.4 15.5 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF3188 PF11384.8 OEU09635.1 - 0.04 13.6 0.2 0.089 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) MFS_2 PF13347.6 OEU09635.1 - 0.068 11.7 0.1 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein CcmD PF04995.14 OEU09635.1 - 0.071 13.2 2.9 0.18 11.9 2.9 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) p450 PF00067.22 OEU09636.1 - 5.7e-20 71.5 0.0 7.4e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2935 PF11155.8 OEU09637.1 - 0.019 15.3 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) IFT20 PF14931.6 OEU09637.1 - 0.083 13.1 3.3 0.17 12.0 3.3 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Thioredoxin PF00085.20 OEU09638.1 - 1.2e-26 92.7 0.0 1.3e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU09638.1 - 3.3e-08 33.8 0.1 1.5e-05 25.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU09638.1 - 4.5e-07 30.3 0.0 2.6e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU09638.1 - 4e-05 23.4 0.1 4.5e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 OEU09638.1 - 0.00024 21.0 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 OEU09638.1 - 0.00041 20.5 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU09638.1 - 0.0005 20.0 0.0 0.0009 19.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU09638.1 - 0.0011 18.8 0.0 0.1 12.3 0.0 2.0 1 1 1 2 2 2 2 Redoxin TraF PF13728.6 OEU09638.1 - 0.0017 18.3 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF366 PF04017.12 OEU09638.1 - 0.022 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF366) Thioredoxin_6 PF13848.6 OEU09638.1 - 0.07 13.0 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 OEU09638.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF4798 PF16055.5 OEU09638.1 - 0.16 12.2 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Thioredoxin PF00085.20 OEU09639.1 - 1.1e-26 92.8 0.0 1.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU09639.1 - 2.2e-08 34.3 0.1 1.1e-05 25.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU09639.1 - 3.3e-07 30.7 0.0 1.7e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU09639.1 - 3.5e-05 23.6 0.1 3.9e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 OEU09639.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 OEU09639.1 - 0.0003 20.9 0.0 0.00043 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU09639.1 - 0.00045 20.1 0.0 0.00084 19.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU09639.1 - 0.00097 18.9 0.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 2 Redoxin TraF PF13728.6 OEU09639.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF366 PF04017.12 OEU09639.1 - 0.024 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF366) Thioredoxin_6 PF13848.6 OEU09639.1 - 0.054 13.4 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 OEU09639.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF836 PF05768.14 OEU09639.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF4798 PF16055.5 OEU09639.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) SQS_PSY PF00494.19 OEU09640.1 - 2.9e-59 200.7 0.0 3.8e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Exotox-A_cataly PF09009.10 OEU09640.1 - 0.051 13.3 0.3 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Exotoxin A catalytic DXP_synthase_N PF13292.6 OEU09640.1 - 0.077 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase MIP PF00230.20 OEU09641.1 - 1.6e-45 155.6 13.9 2.3e-45 155.1 13.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sulfatase PF00884.23 OEU09642.1 - 1.1e-37 130.2 10.0 4.4e-27 95.3 0.8 3.1 3 1 0 3 3 3 2 Sulfatase SR-25 PF10500.9 OEU09642.1 - 0.013 15.1 6.1 0.013 15.1 6.1 3.7 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 OEU09642.1 - 0.024 14.0 0.6 0.044 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3446 PF11928.8 OEU09642.1 - 1.1 9.7 13.4 0.85 10.0 5.4 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Ank_5 PF13857.6 OEU09643.1 - 3.1e-10 40.1 0.3 5e-05 23.5 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU09643.1 - 9.4e-08 32.5 0.1 4e-06 27.3 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU09643.1 - 4.3e-07 29.7 0.1 9.3e-06 25.6 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OEU09643.1 - 4.3e-07 30.4 0.1 2.8e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU09643.1 - 4.5e-05 23.7 0.0 0.0034 17.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF1454 PF07305.12 OEU09644.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) DUF3446 PF11928.8 OEU09645.1 - 0.16 12.3 8.8 0.041 14.2 3.2 2.5 3 0 0 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 OEU09645.1 - 4.3 6.9 10.0 9.3 5.8 10.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PT PF04886.12 OEU09646.1 - 6e-06 25.7 31.5 0.022 14.3 5.3 3.3 1 1 1 2 2 2 2 PT repeat CDC27 PF09507.10 OEU09647.1 - 0.0044 16.5 19.9 0.0044 16.5 19.9 4.1 4 0 0 4 4 4 1 DNA polymerase subunit Cdc27 CRAL_TRIO_N PF03765.15 OEU09647.1 - 0.044 14.0 0.1 0.16 12.2 0.1 2.0 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain IR1-M PF12185.8 OEU09647.1 - 0.58 10.1 6.8 0.087 12.8 0.6 3.0 2 1 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain GST_C PF00043.25 OEU09648.1 - 2e-09 37.5 0.7 5.2e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU09648.1 - 4.3e-05 23.5 0.0 8.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU09648.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OEU09648.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1c PF00749.21 OEU09649.1 - 6.9e-104 347.1 0.4 4.1e-103 344.6 0.3 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OEU09649.1 - 2.1e-27 96.1 0.0 7e-27 94.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 OEU09649.1 - 0.034 13.5 1.1 0.064 12.6 0.7 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Mucin PF01456.17 OEU09650.1 - 0.16 12.0 22.7 0.57 10.2 0.6 2.4 2 1 0 2 2 2 0 Mucin-like glycoprotein p450 PF00067.22 OEU09651.1 - 2e-34 119.1 0.0 2.2e-32 112.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PAP_PilO PF06864.12 OEU09651.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) ABC_tran PF00005.27 OEU09652.1 - 8.3e-28 97.6 1.4 9.6e-28 97.4 0.4 1.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 OEU09652.1 - 7.4e-26 90.9 27.3 1e-25 90.4 27.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OEU09652.1 - 2.4e-08 33.5 9.5 3e-08 33.2 9.5 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OEU09652.1 - 4.4e-05 23.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU09652.1 - 7.6e-05 22.7 0.2 0.00025 21.0 0.2 1.8 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 OEU09652.1 - 0.00018 21.0 2.7 0.00056 19.4 2.7 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU09652.1 - 0.00072 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU09652.1 - 0.0039 17.4 0.4 0.047 14.0 0.4 2.2 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 OEU09652.1 - 0.0067 16.4 0.1 0.025 14.5 0.1 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 OEU09652.1 - 0.026 14.3 0.2 0.12 12.1 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 OEU09652.1 - 0.052 13.3 0.1 0.092 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OEU09652.1 - 0.074 13.5 0.5 0.33 11.4 0.5 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OEU09652.1 - 0.078 12.7 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OEU09652.1 - 0.084 13.0 0.4 0.22 11.6 0.4 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OEU09652.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OEU09652.1 - 0.1 12.3 0.1 0.71 9.6 0.1 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 OEU09652.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OEU09652.1 - 0.15 12.5 2.4 0.6 10.6 2.4 1.7 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.19 OEU09653.1 - 5.6e-14 52.3 8.1 2.3e-13 50.4 8.1 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU09653.1 - 1.2e-12 48.2 2.5 1.6e-12 47.9 2.5 1.2 1 0 0 1 1 1 1 HMG-box domain Imm58 PF15581.6 OEU09653.1 - 0.00093 19.3 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 Immunity protein 58 DUF1264 PF06884.11 OEU09653.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) HTH_AsnC-type PF13404.6 OEU09653.1 - 0.046 13.5 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OEU09655.1 - 1.2e-24 87.2 0.0 1.3e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09655.1 - 2.1e-18 66.6 0.0 2.2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU09655.1 - 0.28 9.9 0.0 0.3 9.8 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Isochorismatase PF00857.20 OEU09657.1 - 4.8e-28 98.5 0.0 6.6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family PT PF04886.12 OEU09658.1 - 0.00017 21.1 21.7 0.00017 21.1 21.7 2.1 2 0 0 2 2 2 1 PT repeat Nab2p_Zf1 PF18260.1 OEU09659.1 - 0.45 10.5 13.9 8.1 6.5 0.9 3.5 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-C3H1 PF10650.9 OEU09659.1 - 1.6 8.5 8.9 53 3.7 0.1 4.6 4 0 0 4 4 4 0 Putative zinc-finger domain HAP2-GCS1 PF10699.9 OEU09659.1 - 4.1 7.5 10.3 37 4.4 0.2 3.7 3 0 0 3 3 3 0 Male gamete fusion factor Toxin_23 PF08093.11 OEU09659.1 - 4.4 7.5 25.3 4.4 7.5 1.7 3.7 3 0 0 3 3 3 0 Magi 5 toxic peptide family DX PF01666.17 OEU09659.1 - 5.4 7.5 16.1 1.8 9.1 0.7 3.7 1 1 2 3 3 3 0 DX module Perm-CXXC PF15629.6 OEU09659.1 - 7 7.0 8.1 82 3.6 0.1 4.3 4 0 0 4 4 4 0 Permuted single zf-CXXC unit Sulfatase PF00884.23 OEU09661.1 - 0.058 12.8 0.1 0.058 12.8 0.1 2.5 1 1 2 3 3 3 0 Sulfatase DUF2269 PF10027.9 OEU09662.1 - 0.12 12.4 1.7 0.29 11.2 1.2 1.8 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) MACPF PF01823.19 OEU09664.1 - 0.024 14.8 0.8 0.024 14.8 0.8 1.6 2 0 0 2 2 2 0 MAC/Perforin domain DUF2076 PF09849.9 OEU09664.1 - 8.9 6.3 8.1 17 5.4 8.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DDE_1 PF03184.19 OEU09665.1 - 0.0018 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Wzy_C_2 PF11846.8 OEU09666.1 - 0.27 11.1 1.2 0.55 10.1 1.2 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal CSG2 PF16965.5 OEU09666.1 - 0.66 8.9 8.4 2.4 7.0 0.4 2.1 1 1 1 2 2 2 0 Ceramide synthase regulator FCP1_C PF09309.10 OEU09666.1 - 2 8.2 10.8 0.5 10.2 7.2 1.8 2 0 0 2 2 2 0 FCP1, C-terminal O-antigen_lig PF13425.6 OEU09666.1 - 3.1 6.5 6.0 5.9 5.6 6.0 1.5 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF1980 PF09323.10 OEU09666.1 - 6.3 6.7 13.3 0.3 11.0 2.7 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF1980) DUF3759 PF12585.8 OEU09667.1 - 0.0036 17.3 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF5386 PF17360.2 OEU09667.1 - 0.0068 16.3 6.2 0.012 15.5 6.2 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5386) DUF4438 PF14505.6 OEU09667.1 - 0.11 11.5 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) FMN_red PF03358.15 OEU09668.1 - 3.7e-19 69.0 0.0 6.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OEU09668.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Ribosomal_60s PF00428.19 OEU09669.1 - 0.0068 17.0 1.3 0.01 16.4 1.2 1.4 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF4468 PF14730.6 OEU09669.1 - 0.13 12.6 1.3 11 6.4 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold EF-hand_6 PF13405.6 OEU09670.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain DUF1635 PF07795.11 OEU09671.1 - 1.1 9.1 8.9 0.19 11.5 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1635) Pyr_redox_2 PF07992.14 OEU09673.1 - 7.8e-63 212.4 0.1 9.6e-63 212.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU09673.1 - 2.8e-32 111.2 2.1 5.4e-32 110.3 2.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU09673.1 - 4.7e-23 81.5 1.1 3.9e-20 72.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU09673.1 - 8.3e-15 54.8 1.2 2.6e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU09673.1 - 1.1e-08 34.2 1.1 0.00022 20.1 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OEU09673.1 - 2.5e-05 23.7 1.3 0.17 11.2 0.1 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OEU09673.1 - 3.3e-05 23.4 1.5 0.0035 16.7 1.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OEU09673.1 - 0.00035 19.8 0.0 0.00077 18.7 0.0 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OEU09673.1 - 0.00044 19.4 2.8 0.012 14.7 1.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OEU09673.1 - 0.0094 16.4 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 OEU09673.1 - 0.048 14.2 0.0 2 9.0 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_2 PF00890.24 OEU09673.1 - 0.068 12.2 5.2 1.2 8.2 2.0 3.3 4 0 0 4 4 4 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OEU09673.1 - 0.074 12.4 0.9 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Myosin_N PF02736.19 OEU09673.1 - 0.098 12.5 5.8 0.42 10.5 0.4 2.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain NAD_binding_9 PF13454.6 OEU09673.1 - 0.13 12.3 2.0 0.2 11.6 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OEU09673.1 - 0.15 12.3 3.5 0.86 9.9 0.9 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OEU09673.1 - 0.19 10.8 1.1 9.5 5.1 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein Dirigent PF03018.14 OEU09674.1 - 0.024 14.5 0.2 0.048 13.4 0.2 1.4 1 0 0 1 1 1 0 Dirigent-like protein PAP_fibrillin PF04755.12 OEU09675.1 - 1.4e-05 25.1 0.1 0.00011 22.2 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin FtsJ PF01728.19 OEU09676.1 - 3.4e-07 30.5 0.0 8.5e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3258 PF11646.8 OEU09676.1 - 0.11 12.6 4.7 0.55 10.4 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF3258 PRK PF00485.18 OEU09677.1 - 1.1e-05 25.2 0.2 0.00012 21.9 0.2 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OEU09677.1 - 1.8e-05 25.3 0.2 7.1e-05 23.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OEU09677.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 OEU09677.1 - 0.11 12.7 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OEU09677.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.17 OEU09677.1 - 0.14 11.9 0.0 18 5.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.21 OEU09677.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytochrom_B561 PF03188.16 OEU09678.1 - 0.00062 19.9 3.7 0.00062 19.9 3.7 3.3 3 1 1 4 4 4 1 Eukaryotic cytochrome b561 DUF2306 PF10067.9 OEU09678.1 - 0.0076 16.5 2.4 0.0076 16.5 2.4 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) RXT2_N PF08595.11 OEU09678.1 - 0.057 13.4 0.4 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Dehydrin PF00257.19 OEU09679.1 - 0.033 14.7 0.2 0.52 10.9 0.0 2.5 2 0 0 2 2 2 0 Dehydrin Fasciclin PF02469.22 OEU09680.1 - 1.1e-67 226.2 7.4 3.4e-32 111.4 0.1 3.1 3 0 0 3 3 3 3 Fasciclin domain PduV-EutP PF10662.9 OEU09680.1 - 0.019 14.7 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF169 PF02596.15 OEU09680.1 - 0.035 14.0 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 Na_H_Exchanger PF00999.21 OEU09682.1 - 1.3e-33 116.3 20.3 1.6e-33 116.0 20.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BRE PF06113.12 OEU09682.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Peptidase_S8 PF00082.22 OEU09683.1 - 3e-34 118.7 1.6 3e-34 118.7 1.6 2.6 2 2 0 2 2 2 1 Subtilase family Mucin PF01456.17 OEU09683.1 - 9e-05 22.5 7.8 0.0066 16.5 4.6 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein TMEM154 PF15102.6 OEU09683.1 - 0.0031 17.4 0.9 0.0063 16.4 0.9 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OEU09683.1 - 0.009 16.9 1.3 0.062 14.2 0.2 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain KCH PF16944.5 OEU09683.1 - 0.017 14.9 0.5 0.026 14.3 0.5 1.2 1 0 0 1 1 1 0 Fungal potassium channel K_channel_TID PF07941.11 OEU09683.1 - 0.047 14.2 2.3 0.12 12.8 2.3 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain HemX PF04375.14 OEU09683.1 - 0.11 11.8 1.7 0.19 11.0 1.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cadherin_C_2 PF16492.5 OEU09683.1 - 0.12 13.2 0.7 2 9.2 0.0 2.7 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 OEU09683.1 - 1.1 9.4 7.1 0.22 11.8 1.6 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator OxoDH_E1alpha_N PF12573.8 OEU09685.1 - 0.13 12.1 0.2 0.3 10.9 0.2 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Phage_GPL PF05926.11 OEU09685.1 - 0.41 10.6 5.2 1.2 9.1 1.3 2.8 3 0 0 3 3 3 0 Phage head completion protein (GPL) Collagen PF01391.18 OEU09686.1 - 0.0075 16.0 0.6 0.014 15.2 0.6 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) HMG_box PF00505.19 OEU09687.1 - 6.8e-23 80.9 13.8 1.7e-14 54.0 1.4 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU09687.1 - 4.5e-13 49.6 11.5 9.1e-08 32.6 4.0 2.1 2 0 0 2 2 2 2 HMG-box domain Penaeidin PF05927.11 OEU09688.1 - 0.39 11.5 0.0 0.39 11.5 0.0 3.2 4 0 0 4 4 4 0 Penaeidin DUF2106 PF09879.9 OEU09689.1 - 0.045 13.3 0.2 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) DUF2561 PF10812.8 OEU09689.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Silic_transp PF03842.13 OEU09690.1 - 9.8e-229 759.9 9.7 1.2e-228 759.5 9.7 1.0 1 0 0 1 1 1 1 Silicon transporter DUF5079 PF16882.5 OEU09690.1 - 0.047 13.6 3.2 0.31 10.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) SF3A3 PF16837.5 OEU09691.1 - 0.075 13.6 0.5 0.4 11.2 0.1 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF3043 PF11241.8 OEU09691.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) RXT2_N PF08595.11 OEU09692.1 - 0.032 14.3 3.4 0.036 14.1 3.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Arcadin_1 PF18653.1 OEU09695.1 - 0.056 13.5 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 Arcadin 1 Lig_chan PF00060.26 OEU09698.1 - 1.4e-15 57.5 0.1 2.5e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel WBP-1 PF11669.8 OEU09698.1 - 0.13 12.9 0.1 1.8 9.3 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Sigma70_ner PF04546.13 OEU09699.1 - 0.0045 16.9 0.2 0.0045 16.9 0.2 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF2207 PF09972.9 OEU09699.1 - 0.17 10.6 9.6 0.59 8.8 0.3 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) FAM176 PF14851.6 OEU09699.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.8 3 0 0 3 3 3 0 FAM176 family Orf78 PF06024.12 OEU09699.1 - 0.19 12.0 9.4 6.5 7.1 1.7 3.7 3 0 0 3 3 3 0 Orf78 (ac78) RPA43_OB PF17875.1 OEU09699.1 - 1.2 9.8 5.3 0.3 11.7 0.4 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I NST1 PF13945.6 OEU09699.1 - 2.1 8.4 21.4 6 6.9 2.1 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF3087 PF11286.8 OEU09699.1 - 3.8 6.9 5.3 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Phage_Gp23 PF10669.9 OEU09699.1 - 7.3 7.0 9.4 12 6.2 1.3 3.1 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) SpoIIIAH PF12685.7 OEU09699.1 - 8.1 6.2 15.0 1.6 8.5 6.1 2.8 3 0 0 3 3 3 0 SpoIIIAH-like protein Sulfotransfer_2 PF03567.14 OEU09700.1 - 1.3e-08 35.0 6.0 1.3e-08 35.0 6.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 OEU09700.1 - 3.9e-05 22.7 0.1 0.41 9.5 0.0 3.1 3 0 0 3 3 3 2 Galactose-3-O-sulfotransferase DUF3292 PF11696.8 OEU09703.1 - 2 6.7 5.5 2.6 6.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4407 PF14362.6 OEU09703.1 - 3.4 6.9 6.0 4.9 6.4 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 OEU09704.1 - 1.5 9.2 4.7 11 6.5 1.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ion_trans_2 PF07885.16 OEU09705.1 - 2.8e-14 52.8 14.9 3.8e-07 30.0 3.7 2.9 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 OEU09705.1 - 0.00095 18.5 0.9 0.00095 18.5 0.9 2.4 2 0 0 2 2 2 2 Ion transport protein TERB2 PF15101.6 OEU09706.1 - 0.03 14.4 4.2 0.043 13.9 4.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SOBP PF15279.6 OEU09706.1 - 0.063 13.9 3.3 0.084 13.5 3.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DDHD PF02862.17 OEU09706.1 - 0.29 11.3 2.4 0.37 10.9 2.4 1.3 1 0 0 1 1 1 0 DDHD domain DUF2151 PF10221.9 OEU09706.1 - 0.49 8.9 6.1 0.72 8.4 6.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator PA26 PF04636.13 OEU09706.1 - 0.54 9.1 5.4 0.66 8.8 5.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EOS1 PF12326.8 OEU09706.1 - 0.64 9.9 1.6 0.92 9.4 1.6 1.4 1 0 0 1 1 1 0 N-glycosylation protein EMC3_TMCO1 PF01956.16 OEU09706.1 - 0.72 9.6 3.6 1.4 8.7 3.6 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2828 PF11443.8 OEU09706.1 - 1.2 7.1 12.5 1.5 6.8 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4569 PF15133.6 OEU09706.1 - 1.2 8.8 5.1 2.1 8.0 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF1043 PF06295.12 OEU09706.1 - 1.5 8.9 11.8 2.3 8.2 7.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) SARAF PF06682.12 OEU09706.1 - 2.9 7.5 19.8 0.018 14.7 4.0 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ALMT PF11744.8 OEU09706.1 - 2.9 6.6 7.0 3.4 6.4 7.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 OEU09706.1 - 3.9 5.5 6.8 4.5 5.3 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3450 PF11932.8 OEU09706.1 - 4.3 6.6 13.4 6.6 6.0 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1943 PF09172.11 OEU09706.1 - 4.6 6.4 6.1 5.8 6.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) AAA_11 PF13086.6 OEU09706.1 - 4.9 6.9 15.3 6.8 6.4 15.3 1.2 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 OEU09706.1 - 5 6.2 8.6 13 4.8 8.9 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OEU09706.1 - 5.3 7.0 5.1 7.1 6.6 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Transformer PF06495.11 OEU09706.1 - 7.5 6.6 26.9 5.1e+02 0.6 26.8 2.3 1 1 0 1 1 1 0 Fruit fly transformer protein SLC12 PF03522.15 OEU09706.1 - 8.1 5.3 11.7 11 4.9 11.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 OEU09706.1 - 8.9 5.2 14.4 11 4.9 14.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SelP_N PF04592.14 OEU09706.1 - 9.5 5.5 12.0 18 4.7 12.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Paramyxo_ncap PF00973.19 OEU09706.1 - 9.5 5.0 9.2 12 4.6 9.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Clathrin_H_link PF13838.6 OEU09707.1 - 0.009 15.9 0.0 0.009 15.9 0.0 1.7 2 0 0 2 2 2 1 Clathrin-H-link DUF4479 PF14794.6 OEU09707.1 - 0.025 14.4 0.8 0.025 14.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Halogen_Hydrol PF10112.9 OEU09707.1 - 1.8 8.5 8.0 3.3 7.7 8.1 1.6 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Radical_SAM PF04055.21 OEU09708.1 - 1.1e-09 38.9 0.1 2.4e-09 37.8 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 OEU09708.1 - 3e-06 27.4 0.0 5.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 OEU09708.1 - 0.00048 20.4 0.0 0.00085 19.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain PT PF04886.12 OEU09710.1 - 1.8 8.2 13.1 1.4 8.5 10.1 2.3 2 1 0 2 2 2 0 PT repeat SAP25 PF15476.6 OEU09712.1 - 0.019 14.6 0.6 0.033 13.9 0.6 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 CRAL_TRIO PF00650.20 OEU09714.1 - 1.3e-08 34.7 0.0 3.4e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain COMP PF11598.8 OEU09714.1 - 0.083 13.4 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Zip PF02535.22 OEU09715.1 - 1.8e-19 70.1 0.0 2.3e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter MAM33 PF02330.16 OEU09715.1 - 0.0084 16.1 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein PBP1_TM PF14812.6 OEU09715.1 - 0.027 14.8 0.2 0.027 14.8 0.2 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTD PF09270.10 OEU09715.1 - 0.032 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain BSMAP PF12280.8 OEU09715.1 - 0.11 12.7 1.7 0.2 11.8 1.7 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4064 PF13273.6 OEU09715.1 - 0.16 12.3 0.9 0.66 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SET PF00856.28 OEU09716.1 - 2.6e-06 27.9 0.0 0.00023 21.6 0.0 2.4 1 1 0 1 1 1 1 SET domain SAF PF08666.12 OEU09716.1 - 0.013 16.1 0.0 9.6 6.9 0.0 2.5 2 0 0 2 2 2 0 SAF domain DUF4689 PF15755.5 OEU09716.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Dirigent PF03018.14 OEU09717.1 - 0.009 15.8 0.2 0.027 14.3 0.2 1.8 2 0 0 2 2 2 1 Dirigent-like protein Methyltransf_31 PF13847.6 OEU09718.1 - 2.6e-06 27.3 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU09718.1 - 4.9e-06 27.2 0.0 5.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU09718.1 - 9.6e-05 22.4 0.1 0.00011 22.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU09718.1 - 0.00019 22.0 0.0 0.00024 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU09718.1 - 0.00034 20.2 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OEU09718.1 - 0.0013 19.4 0.1 0.0016 19.1 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU09718.1 - 0.0085 15.9 0.0 0.0086 15.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OEU09718.1 - 0.0088 15.7 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Eno-Rase_NADH_b PF12242.8 OEU09718.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PrmA PF06325.13 OEU09718.1 - 0.05 13.0 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AAA_12 PF13087.6 OEU09719.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain eIF-6 PF01912.18 OEU09720.1 - 1.9e-73 246.0 0.1 4.3e-73 244.9 0.1 1.5 2 0 0 2 2 2 1 eIF-6 family 6PF2K PF01591.18 OEU09721.1 - 4.9e-65 219.0 0.4 8.2e-65 218.2 0.4 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OEU09721.1 - 7.2e-29 100.9 0.0 9e-21 74.4 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OEU09721.1 - 2e-09 37.8 0.1 6e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OEU09721.1 - 0.015 15.0 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 OEU09721.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 OEU09721.1 - 0.11 12.9 0.1 0.44 11.0 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CENP-B_dimeris PF09026.10 OEU09721.1 - 2.5 8.5 9.5 0.51 10.8 4.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Abhydrolase_1 PF00561.20 OEU09722.1 - 1.7e-05 24.6 0.0 0.00015 21.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OEU09722.1 - 2.3e-05 24.2 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 OEU09722.1 - 0.00031 20.0 0.2 0.0008 18.7 0.0 1.6 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 OEU09722.1 - 0.0032 18.1 0.0 0.0036 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU09722.1 - 0.0033 16.7 0.0 0.0073 15.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OEU09722.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 OEU09722.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PMC2NT PF08066.12 OEU09723.1 - 7.1 7.4 8.5 1.2 9.8 1.2 3.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain zf-TRAF PF02176.18 OEU09724.1 - 0.0095 16.6 0.3 0.043 14.5 0.3 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger Y_phosphatase3 PF13350.6 OEU09727.1 - 3.5e-17 63.2 2.0 9.9e-17 61.7 2.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OEU09727.1 - 0.00013 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 OEU09727.1 - 0.00099 18.7 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 OEU09727.1 - 0.001 18.1 2.6 0.0011 18.0 1.8 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 OEU09727.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OEU09727.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Amino_oxidase PF01593.24 OEU09729.1 - 7.2e-60 203.5 0.0 5e-59 200.8 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU09729.1 - 7e-09 35.8 0.2 7e-07 29.4 0.2 2.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RPM2 PF08579.11 OEU09729.1 - 2.5e-05 24.6 6.4 2.5e-05 24.6 6.4 2.1 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) NAD_binding_9 PF13454.6 OEU09729.1 - 0.074 13.0 0.1 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Silic_transp PF03842.13 OEU09730.1 - 3.9e-211 701.8 11.0 1.1e-209 697.0 11.0 2.0 1 1 0 1 1 1 1 Silicon transporter DUF5079 PF16882.5 OEU09730.1 - 0.0095 15.8 2.4 0.17 11.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5079) Glyco_tranf_2_3 PF13641.6 OEU09731.1 - 1.6e-10 41.3 0.0 0.00012 22.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OEU09731.1 - 7.2e-10 39.1 0.5 7.2e-10 39.1 0.5 2.9 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OEU09731.1 - 0.014 15.2 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 AAA_33 PF13671.6 OEU09733.1 - 0.00013 22.2 0.0 0.0023 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OEU09733.1 - 0.048 12.9 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SKG6 PF08693.10 OEU09734.1 - 0.061 12.7 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 OEU09734.1 - 0.7 10.0 0.0 0.7 10.0 0.0 3.2 2 1 1 3 3 3 0 Podoplanin CRAL_TRIO PF00650.20 OEU09737.1 - 1.2e-28 99.8 0.1 2.3e-28 98.9 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU09737.1 - 0.0071 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_Mx1 PF15890.5 OEU09737.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase OAF PF14941.6 OEU09738.1 - 0.13 11.7 1.3 0.18 11.2 1.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator, Out at first PQ-loop PF04193.14 OEU09740.1 - 5.3e-06 26.1 1.4 5.3e-06 26.1 1.4 3.4 4 0 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 OEU09740.1 - 0.028 15.3 13.4 0.028 15.3 13.4 2.0 1 1 1 2 2 2 0 ER lumen protein retaining receptor Dirigent PF03018.14 OEU09741.1 - 0.019 14.7 0.9 0.042 13.6 0.9 1.5 1 0 0 1 1 1 0 Dirigent-like protein PMSR PF01625.21 OEU09742.1 - 5.1e-43 146.9 2.0 6.6e-43 146.5 2.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4197 PF13852.6 OEU09742.1 - 0.027 14.1 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) PT PF04886.12 OEU09743.1 - 1.1e-13 50.4 57.6 5e-07 29.2 17.0 3.1 1 1 2 3 3 3 3 PT repeat PUB PF09409.10 OEU09746.1 - 9.5e-14 51.1 0.5 3.2e-13 49.4 0.5 1.9 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 OEU09746.1 - 2.3e-06 27.7 0.0 5.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain Beta_helix PF13229.6 OEU09747.1 - 2.1e-08 34.2 9.5 2.1e-08 34.2 9.5 3.9 2 1 1 3 3 3 1 Right handed beta helix region Cupin_3 PF05899.12 OEU09748.1 - 2e-18 65.8 0.0 9.8e-13 47.6 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OEU09748.1 - 2e-05 24.2 0.0 0.0011 18.7 0.0 2.7 2 1 0 2 2 2 1 Cupin domain ARD PF03079.14 OEU09748.1 - 0.0049 17.1 1.3 0.23 11.6 0.0 2.8 2 1 1 3 3 3 1 ARD/ARD' family PRR18 PF15671.5 OEU09750.1 - 0.065 13.1 4.5 1.3 8.9 0.0 2.3 2 1 0 2 2 2 0 Proline-rich protein family 18 DUF1700 PF08006.11 OEU09751.1 - 0.042 13.4 1.3 0.094 12.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Glyco_transf_41 PF13844.6 OEU09752.1 - 4.3e-11 41.9 0.4 2.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 DUF1132 PF06575.12 OEU09752.1 - 0.08 13.3 0.1 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) Dirigent PF03018.14 OEU09753.1 - 0.021 14.6 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 Dirigent-like protein IPP-2 PF04979.14 OEU09754.1 - 2.9e-21 76.6 4.9 2.9e-21 76.6 4.9 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Macoilin PF09726.9 OEU09754.1 - 3.8 6.0 10.7 4.7 5.6 10.7 1.2 1 0 0 1 1 1 0 Macoilin family Cu-oxidase_2 PF07731.14 OEU09755.1 - 7.8 6.2 7.7 0.33 10.7 0.2 2.5 3 1 0 3 3 3 0 Multicopper oxidase TPR_2 PF07719.17 OEU09756.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU09756.1 - 0.021 14.7 0.3 0.046 13.6 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5352 PF17303.2 OEU09757.1 - 0.1 12.4 1.2 0.13 12.1 0.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5352) Imm58 PF15581.6 OEU09757.1 - 0.11 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 58 Fib_alpha PF08702.10 OEU09757.1 - 0.69 10.1 7.8 0.064 13.4 3.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TK PF00265.18 OEU09758.1 - 0.013 15.4 1.3 0.025 14.4 1.3 1.6 1 0 0 1 1 1 0 Thymidine kinase ApbA PF02558.16 OEU09758.1 - 0.096 12.3 3.9 0.095 12.3 2.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF1189 PF06691.11 OEU09758.1 - 0.48 10.0 5.9 0.83 9.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) SAGA-Tad1 PF12767.7 OEU09758.1 - 7.8 6.2 28.0 1.8e+04 -4.8 28.0 2.5 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Presenilin PF01080.17 OEU09759.1 - 0.96 8.1 6.2 1.3 7.7 0.5 2.2 2 0 0 2 2 2 0 Presenilin TRA-1_regulated PF02343.16 OEU09761.1 - 0.012 15.7 0.4 0.018 15.1 0.4 1.3 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 DUF3446 PF11928.8 OEU09761.1 - 0.059 13.7 2.6 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain DotU PF09850.9 OEU09761.1 - 0.06 13.1 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system protein DotU TMEM171 PF15471.6 OEU09761.1 - 0.063 12.3 1.7 0.066 12.2 0.4 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 DUF2935 PF11155.8 OEU09765.1 - 0.019 15.3 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) IFT20 PF14931.6 OEU09765.1 - 0.1 12.8 3.7 0.22 11.7 3.7 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 LETM1 PF07766.13 OEU09767.1 - 0.0022 17.4 2.1 0.0024 17.3 2.1 1.0 1 0 0 1 1 1 1 LETM1-like protein DUF4834 PF16118.5 OEU09767.1 - 0.0079 17.1 1.1 0.0097 16.9 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Peptidase_S49_N PF08496.10 OEU09767.1 - 0.01 15.9 4.2 0.011 15.8 4.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal KIP1 PF07765.12 OEU09767.1 - 0.036 14.2 2.5 0.041 14.0 1.8 1.5 1 1 1 2 2 2 0 KIP1-like protein Connexin PF00029.19 OEU09767.1 - 0.05 13.4 3.7 0.051 13.3 3.7 1.0 1 0 0 1 1 1 0 Connexin OATP PF03137.20 OEU09767.1 - 0.17 10.1 0.2 0.18 10.0 0.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CHD5 PF04420.14 OEU09767.1 - 0.18 11.7 3.0 0.081 12.8 1.0 1.4 1 1 1 2 2 2 0 CHD5-like protein EphA2_TM PF14575.6 OEU09767.1 - 0.71 10.8 4.4 1.7 9.6 4.4 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2701 PF10857.8 OEU09768.1 - 1.8 8.6 6.1 0.44 10.6 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2701) CYSTM PF12734.7 OEU09768.1 - 5.1 7.5 6.5 7 7.1 0.0 2.7 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance TPR_12 PF13424.6 OEU09769.1 - 5.7e-11 42.6 1.7 0.00015 22.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU09769.1 - 6.2e-07 29.1 1.0 0.11 12.4 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU09769.1 - 0.0087 16.1 9.3 0.83 9.9 0.4 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU09769.1 - 0.083 13.0 0.3 1.1 9.4 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat CD20 PF04103.15 OEU09769.1 - 0.52 10.4 4.8 0.3 11.1 0.1 3.1 2 0 0 2 2 2 0 CD20-like family CDH1_2_SANT_HL1 PF18375.1 OEU09769.1 - 1 10.1 0.0 1 10.1 0.0 5.1 5 1 0 5 5 5 0 CDH1/2 SANT-Helical linker 1 DEP PF00610.21 OEU09770.1 - 1.7e-11 44.0 0.1 3.6e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) C2 PF00168.30 OEU09770.1 - 0.0018 18.5 0.0 0.057 13.7 0.0 2.5 2 0 0 2 2 2 1 C2 domain DUF3215 PF11503.8 OEU09770.1 - 0.089 12.7 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DDE_1 PF03184.19 OEU09773.1 - 0.097 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Acetyltransf_3 PF13302.7 OEU09774.1 - 6.9e-22 78.6 0.0 8.5e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU09774.1 - 2e-07 31.3 0.0 4.4e-07 30.1 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OEU09774.1 - 0.021 14.5 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RSV_NS2 PF03113.14 OEU09774.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 DUF645 PF04875.12 OEU09775.1 - 0.066 13.3 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF645 DUF4603 PF15376.6 OEU09775.1 - 0.068 10.6 7.9 0.11 9.9 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CSG2 PF16965.5 OEU09775.1 - 4.2 6.2 5.7 9.5 5.0 5.7 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator Voltage_CLC PF00654.20 OEU09776.1 - 1.1e-38 133.4 35.4 2.1e-37 129.2 27.2 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel Leg1 PF05612.12 OEU09777.1 - 0.00011 21.4 1.9 0.17 11.0 0.0 2.8 2 1 1 3 3 3 2 Leg1 CHAT PF12770.7 OEU09777.1 - 0.0099 15.3 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 CHAT domain BAT2_N PF07001.11 OEU09777.1 - 0.25 11.8 1.6 0.48 10.9 1.6 1.4 1 0 0 1 1 1 0 BAT2 N-terminus FKBP_C PF00254.28 OEU09778.1 - 1.9e-05 24.9 0.0 3.1e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aa_trans PF01490.18 OEU09779.1 - 4.1e-57 193.7 19.1 4.6e-57 193.6 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU09779.1 - 0.0011 18.1 11.3 0.0011 18.1 11.3 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family TarH PF02203.15 OEU09779.1 - 0.065 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Oxidored_q3 PF00499.20 OEU09780.1 - 5.4e-05 22.9 3.2 0.00041 20.1 0.5 2.5 2 1 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 HD_assoc PF13286.6 OEU09780.1 - 0.12 12.9 0.1 0.44 11.1 0.1 1.8 1 1 0 1 1 1 0 Phosphohydrolase-associated domain DUF1218 PF06749.12 OEU09780.1 - 2.1 9.0 6.8 0.94 10.0 1.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1218) FAD_binding_4 PF01565.23 OEU09781.1 - 7.2e-11 42.0 0.2 1.1e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GTP_cyclohydroI PF01227.22 OEU09782.1 - 3.2e-23 82.1 0.1 3.4e-23 82.0 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I FKBP_C PF00254.28 OEU09783.1 - 4.5e-10 39.7 0.0 6.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF150_C PF17384.2 OEU09784.1 - 0.058 13.5 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Rhomboid PF01694.22 OEU09785.1 - 1.3e-24 86.9 9.4 3.6e-24 85.5 9.4 1.8 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 OEU09785.1 - 0.03 14.2 4.8 0.072 13.0 4.8 1.8 1 1 0 1 1 1 0 Der1-like family DUF1751 PF08551.10 OEU09785.1 - 0.13 12.9 0.2 0.13 12.9 0.2 2.6 3 1 1 4 4 4 0 Eukaryotic integral membrane protein (DUF1751) DUF4191 PF13829.6 OEU09785.1 - 0.18 11.1 1.1 0.29 10.4 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) PPV_E1_N PF00524.18 OEU09786.1 - 0.016 15.6 0.6 0.029 14.8 0.6 1.5 1 1 0 1 1 1 0 E1 Protein, N terminal domain TPR_2 PF07719.17 OEU09787.1 - 0.011 15.8 1.8 1.9 8.8 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU09787.1 - 0.073 12.9 1.3 1 9.3 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SBF_like PF13593.6 OEU09789.1 - 5.5e-75 252.6 21.1 6.2e-75 252.4 21.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 OEU09789.1 - 2.5e-13 50.1 5.9 2.5e-13 50.1 5.9 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 OEU09789.1 - 0.0018 16.7 4.4 0.0018 16.7 4.4 2.1 2 1 0 2 2 2 1 Membrane transport protein DUF624 PF04854.14 OEU09789.1 - 0.0056 16.8 0.2 0.0056 16.8 0.2 4.4 4 2 0 4 4 4 1 Protein of unknown function, DUF624 DUF4131 PF13567.6 OEU09789.1 - 3.2 7.4 5.6 17 5.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) LRR_8 PF13855.6 OEU09790.1 - 0.0023 17.7 9.7 1.2 8.9 1.0 5.0 5 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 OEU09790.1 - 0.036 14.5 18.1 3.4 8.2 2.8 5.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) CUE PF02845.16 OEU09792.1 - 8.1e-06 25.4 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 CUE domain MS_channel PF00924.18 OEU09793.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Spc42p PF11544.8 OEU09793.1 - 0.045 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p Porin_3 PF01459.22 OEU09794.1 - 3e-23 82.6 0.0 3.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin VHL PF01847.16 OEU09795.1 - 2.1e-07 30.7 0.6 0.86 9.6 0.0 5.0 1 1 4 5 5 5 3 VHL beta domain DUF2179 PF10035.9 OEU09795.1 - 0.00067 19.4 0.0 63 3.4 0.0 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2179) NMU PF02070.15 OEU09795.1 - 1.8 8.5 6.3 1e+02 2.9 0.1 4.1 3 0 0 3 3 3 0 Neuromedin U Amidase PF01425.21 OEU09796.1 - 6.6e-60 203.3 1.7 3.6e-42 144.9 4.8 3.3 2 1 1 3 3 3 2 Amidase DUF3439 PF11921.8 OEU09796.1 - 0.083 12.9 9.2 0.19 11.7 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF218 PF02698.17 OEU09797.1 - 1.8e-10 40.9 0.0 1.5e-09 38.0 0.0 2.3 2 1 0 2 2 2 1 DUF218 domain Shisa PF13908.6 OEU09797.1 - 0.029 14.6 0.6 0.086 13.1 0.6 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ureide_permease PF07168.11 OEU09797.1 - 0.86 8.3 5.2 0.067 11.9 0.4 1.5 2 0 0 2 2 2 0 Ureide permease DUF1980 PF09323.10 OEU09797.1 - 0.93 9.4 7.2 0.083 12.8 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) UPF0669 PF17065.5 OEU09797.1 - 1.4 8.6 7.1 0.094 12.5 1.1 1.9 2 0 0 2 2 2 0 Putative cytokine, C6ORF120 Methyltransf_32 PF13679.6 OEU09797.1 - 4.9 7.1 8.0 8.7 6.3 1.2 3.0 3 0 0 3 3 3 0 Methyltransferase domain Trypsin PF00089.26 OEU09798.1 - 5.1e-14 52.6 1.3 4.5e-12 46.3 0.1 2.8 2 1 0 2 2 2 1 Trypsin Toxin_18 PF08087.11 OEU09798.1 - 0.35 10.9 6.2 0.79 9.8 6.2 1.6 1 0 0 1 1 1 0 Conotoxin O-superfamily Toxin_19 PF08088.12 OEU09798.1 - 0.45 10.7 8.2 1.1 9.4 8.2 1.6 1 0 0 1 1 1 0 Conotoxin I-superfamily Conotoxin PF02950.17 OEU09798.1 - 0.57 11.2 7.1 2 9.5 7.1 2.0 1 0 0 1 1 1 0 Conotoxin Conotoxin_I2 PF17557.2 OEU09798.1 - 4.1 7.6 11.2 8.2 6.6 11.2 1.5 1 0 0 1 1 1 0 I2-superfamily conotoxins CTP_transf_like PF01467.26 OEU09799.1 - 6.5e-06 26.4 3.0 0.0082 16.3 0.1 2.4 1 1 0 2 2 2 2 Cytidylyltransferase-like DUF2487 PF10673.9 OEU09799.1 - 0.04 13.9 1.5 0.084 12.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) RPA43_OB PF17875.1 OEU09799.1 - 0.42 11.2 0.1 0.42 11.2 0.1 2.5 2 1 0 2 2 2 0 RPA43 OB domain in RNA Pol I Orf78 PF06024.12 OEU09799.1 - 7.5 6.9 9.2 14 6.1 1.2 2.5 2 0 0 2 2 2 0 Orf78 (ac78) DUF1676 PF07898.13 OEU09799.1 - 7.8 6.5 6.7 1.1 9.3 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) F-box-like PF12937.7 OEU09800.1 - 6.2e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU09800.1 - 7e-06 25.8 0.0 3.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OEU09800.1 - 0.01 15.7 0.1 0.049 13.5 0.0 2.1 2 0 0 2 2 2 0 F-box Rieske PF00355.26 OEU09801.1 - 3.5e-09 36.5 0.0 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OEU09801.1 - 9e-07 28.8 0.0 2.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain CENP-B_dimeris PF09026.10 OEU09801.1 - 0.12 12.8 0.4 0.12 12.8 0.4 2.7 2 1 1 3 3 3 0 Centromere protein B dimerisation domain DUF5401 PF17380.2 OEU09801.1 - 3.5 5.6 26.2 5.6 4.9 26.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Peptidase_M16 PF00675.20 OEU09802.1 - 4.3e-18 65.7 0.1 7.7e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 OEU09802.1 - 0.022 14.0 0.2 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 OEU09802.1 - 0.031 14.3 0.0 0.096 12.7 0.0 1.9 1 1 0 1 1 1 0 Peptidase M16 inactive domain GST_N_2 PF13409.6 OEU09803.1 - 6e-17 61.7 0.1 2e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU09803.1 - 1.6e-12 47.6 0.0 4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU09803.1 - 4.4e-09 36.5 0.1 7.4e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU09803.1 - 1.1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OEU09803.1 - 2.5e-08 34.5 0.0 3.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU09803.1 - 2.3e-07 30.9 0.1 4.1e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU09803.1 - 4.2e-06 27.0 0.0 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU09803.1 - 0.0072 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Trypsin PF00089.26 OEU09804.1 - 0.02 14.7 0.1 0.022 14.6 0.1 1.0 1 0 0 1 1 1 0 Trypsin MLVIN_C PF18697.1 OEU09804.1 - 0.14 12.2 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain PhoQ_Sensor PF08918.10 OEU09806.1 - 10 6.0 7.3 6.5 6.6 1.2 2.8 3 0 0 3 3 3 0 PhoQ Sensor WD40 PF00400.32 OEU09807.1 - 5.1e-22 77.8 23.3 1.2e-06 29.1 0.6 7.2 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU09807.1 - 1.2e-07 31.9 0.3 0.0024 18.1 0.1 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU09807.1 - 1e-05 24.7 4.7 0.00072 18.6 0.1 3.7 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PSII_BNR PF14870.6 OEU09807.1 - 0.049 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Hira PF07569.11 OEU09807.1 - 0.12 12.0 0.3 5.4 6.7 0.0 2.8 1 1 1 2 2 2 0 TUP1-like enhancer of split DUF515 PF04415.12 OEU09808.1 - 0.035 12.5 0.3 0.042 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) S_100 PF01023.19 OEU09808.1 - 0.76 9.5 2.2 7.9 6.3 0.1 2.9 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain Trypsin PF00089.26 OEU09811.1 - 2e-48 165.1 0.0 2.7e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU09811.1 - 3.6e-10 40.9 0.0 5.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Toxin_21 PF08091.11 OEU09811.1 - 0.56 10.2 9.7 1.5 8.8 9.7 1.7 1 0 0 1 1 1 0 Spider insecticidal peptide Conotoxin_I2 PF17557.2 OEU09811.1 - 0.63 10.2 9.0 1.5 9.0 9.0 1.6 1 0 0 1 1 1 0 I2-superfamily conotoxins Conotoxin PF02950.17 OEU09811.1 - 1.5 9.9 5.9 3.1 8.9 4.4 2.2 2 0 0 2 2 2 0 Conotoxin adh_short PF00106.25 OEU09812.1 - 3.1e-31 108.4 0.0 6.7e-24 84.4 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU09812.1 - 1.6e-23 83.5 0.0 3e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU09812.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain RNA_pol_Rpc34 PF05158.12 OEU09812.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Herpes_UL32 PF06070.11 OEU09814.1 - 0.0019 16.1 0.2 0.0022 15.9 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 Herpes_UL25 PF01499.16 OEU09814.1 - 0.019 13.5 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family ECH_1 PF00378.20 OEU09815.1 - 1.5e-42 145.6 0.0 3.5e-41 141.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU09815.1 - 1.3e-13 51.2 0.0 1.7e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OEU09815.1 - 0.082 12.8 0.1 2.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Peptidase family S49 ERCC4 PF02732.15 OEU09816.1 - 0.02 15.1 0.0 0.077 13.2 0.0 2.0 1 0 0 1 1 1 0 ERCC4 domain RAP80_UIM PF18282.1 OEU09816.1 - 0.093 12.5 1.2 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Pex19 PF04614.12 OEU09816.1 - 0.12 12.1 7.8 0.23 11.2 7.8 1.4 1 0 0 1 1 1 0 Pex19 protein family Exo_endo_phos PF03372.23 OEU09817.1 - 0.0002 21.0 0.0 0.00053 19.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU09817.1 - 0.00063 20.4 4.0 0.0024 18.6 4.0 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 OEU09817.1 - 0.0013 18.3 0.1 0.0047 16.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GARS_A PF01071.19 OEU09817.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2107 PF09880.9 OEU09818.1 - 0.086 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) Chi-conotoxin PF16981.5 OEU09819.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.4 3 0 0 3 3 3 0 chi-Conotoxin or t superfamily Conotoxin PF02950.17 OEU09819.1 - 0.82 10.7 1.9 7.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Conotoxin Zip PF02535.22 OEU09819.1 - 1.2 8.2 4.3 1.1 8.4 2.4 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3446 PF11928.8 OEU09820.1 - 5.7 7.3 10.0 0.85 10.0 1.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain DAO PF01266.24 OEU09822.1 - 1.2e-11 44.8 0.0 5.9e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OEU09822.1 - 0.0036 17.3 0.1 0.016 15.2 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding YpmT PF17431.2 OEU09823.1 - 0.002 18.1 0.2 0.89 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized YmpT-like zf-UBP PF02148.19 OEU09824.1 - 4.7e-15 55.7 9.1 5.7e-15 55.4 9.1 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ROQ_II PF18386.1 OEU09824.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Roquin II domain PIG-U PF06728.13 OEU09826.1 - 0.3 10.1 0.7 0.33 9.9 0.7 1.0 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U TAFII28 PF04719.14 OEU09827.1 - 1.8e-05 24.7 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 2 hTAFII28-like protein conserved region PBP1_TM PF14812.6 OEU09827.1 - 3.8 7.9 13.2 3.9 7.9 5.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3494 PF11999.8 OEU09829.1 - 6.4e-50 169.7 11.5 7.3e-50 169.5 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Yae1_N PF09811.9 OEU09830.1 - 6.4e-10 38.6 25.1 7.6 6.3 0.2 9.7 1 1 8 9 9 9 9 Essential protein Yae1, N terminal Rick_17kDa_Anti PF05433.15 OEU09830.1 - 0.00087 19.1 23.5 1.7 8.6 0.2 6.4 1 1 8 9 9 9 4 Glycine zipper 2TM domain DUF4567 PF15131.6 OEU09830.1 - 0.0029 17.6 14.4 19 5.4 0.1 6.0 5 4 0 5 5 5 3 Domain of unknown function (DUF4567) DUF2107 PF09880.9 OEU09830.1 - 0.032 14.3 0.3 1.4e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Predicted membrane protein (DUF2107) MspA PF09203.11 OEU09830.1 - 2.6 7.9 7.6 7.1e+02 -0.1 7.6 3.2 1 1 0 1 1 1 0 MspA PT PF04886.12 OEU09831.1 - 0.00016 21.2 15.0 0.9 9.1 15.0 2.5 1 1 0 1 1 1 1 PT repeat PT PF04886.12 OEU09832.1 - 4.5e-10 38.9 66.8 0.0016 18.0 3.3 7.4 2 1 4 6 6 6 4 PT repeat PAM2 PF07145.15 OEU09832.1 - 0.039 13.7 17.0 8.2 6.4 0.6 6.1 4 0 0 4 4 4 0 Ataxin-2 C-terminal region PT PF04886.12 OEU09833.1 - 1.1e-05 24.9 14.4 0.0012 18.3 2.8 2.2 1 1 1 2 2 2 2 PT repeat PT PF04886.12 OEU09834.1 - 2e-09 36.8 42.4 0.00015 21.2 5.2 4.6 2 2 2 4 4 4 4 PT repeat Kinesin PF00225.23 OEU09835.1 - 6.7e-93 311.2 0.0 7.8e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU09835.1 - 2e-15 57.0 0.1 1.7e-09 37.8 0.1 2.3 2 0 0 2 2 2 2 Microtubule binding T2SSE PF00437.20 OEU09835.1 - 0.071 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Osteopontin PF00865.18 OEU09835.1 - 0.46 9.9 8.9 0.78 9.2 8.9 1.3 1 0 0 1 1 1 0 Osteopontin AGTRAP PF06396.11 OEU09836.1 - 0.041 13.7 1.1 0.041 13.7 1.1 1.8 1 1 1 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Zip PF02535.22 OEU09836.1 - 1 8.5 9.8 1.7 7.8 9.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TIP120 PF08623.10 OEU09836.1 - 3 7.6 9.8 0.99 9.1 2.9 2.2 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) FAM76 PF16046.5 OEU09836.1 - 8.1 5.7 29.2 6.3 6.1 16.1 2.2 2 0 0 2 2 2 0 FAM76 protein CorA PF01544.18 OEU09836.1 - 8.7 5.6 9.3 5 6.4 1.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SET PF00856.28 OEU09837.1 - 1.1e-05 25.9 0.0 0.00082 19.8 0.0 2.4 1 1 0 1 1 1 1 SET domain LRR_8 PF13855.6 OEU09838.1 - 7.7e-10 38.4 3.9 2.4e-08 33.6 0.9 2.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU09838.1 - 5.8e-06 26.5 8.1 0.0016 18.8 0.3 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) ANAPC1 PF12859.7 OEU09838.1 - 0.078 13.5 0.6 0.15 12.7 0.0 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Sulfotransfer_4 PF17784.1 OEU09839.1 - 6.3e-05 22.9 0.3 0.00024 21.0 0.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain DUF4407 PF14362.6 OEU09839.1 - 1.5 8.1 3.1 2.3 7.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IQ PF00612.27 OEU09840.1 - 3.2e-05 23.3 6.9 0.015 15.0 0.7 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Fcf1 PF04900.12 OEU09841.1 - 0.00027 21.3 0.8 0.00055 20.3 0.0 2.0 2 1 0 2 2 2 1 Fcf1 bMG10 PF17973.1 OEU09841.1 - 0.059 13.6 1.3 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain HydF_tetramer PF18133.1 OEU09841.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain Chordopox_G3 PF06129.12 OEU09841.1 - 2.6 8.8 6.7 0.83 10.4 1.5 2.5 1 1 1 2 2 2 0 Chordopoxvirus G3 protein DUF3494 PF11999.8 OEU09842.1 - 1.9e-53 181.2 18.6 2.1e-53 181.0 18.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) PT PF04886.12 OEU09842.1 - 0.034 13.7 0.2 0.034 13.7 0.2 2.3 2 0 0 2 2 2 0 PT repeat PT PF04886.12 OEU09843.1 - 2e-19 68.8 85.7 0.00017 21.1 11.4 7.6 1 1 3 4 4 4 3 PT repeat Yae1_N PF09811.9 OEU09844.1 - 3.6e-13 49.0 48.3 5.8 6.7 1.4 13.2 2 1 4 6 6 6 4 Essential protein Yae1, N terminal MtrG PF04210.13 OEU09844.1 - 0.07 13.0 28.8 19 5.2 0.4 9.6 3 2 5 8 8 8 0 Tetrahydromethanopterin S-methyltransferase, subunit G Rick_17kDa_Anti PF05433.15 OEU09844.1 - 0.19 11.6 48.9 0.29 11.0 0.2 8.5 2 1 7 9 9 9 0 Glycine zipper 2TM domain Phage_CI_repr PF07022.13 OEU09844.1 - 0.28 11.3 3.9 24 5.1 0.1 5.0 7 0 0 7 7 7 0 Bacteriophage CI repressor helix-turn-helix domain Transgly_assoc PF04226.13 OEU09844.1 - 0.32 11.3 39.3 2e+02 2.3 0.8 10.7 1 1 5 6 6 6 0 Transglycosylase associated protein DUF697 PF05128.12 OEU09844.1 - 0.81 9.4 7.5 15 5.3 0.3 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF697) Gly-zipper_Omp PF13488.6 OEU09844.1 - 1.6 8.8 39.2 12 6.0 0.0 7.8 2 1 4 6 6 6 0 Glycine zipper MspA PF09203.11 OEU09844.1 - 2.5 7.9 12.1 6.4e+03 -3.2 11.1 4.1 1 1 0 1 1 1 0 MspA Yae1_N PF09811.9 OEU09845.1 - 1.3e-10 40.8 39.3 0.43 10.3 0.1 13.2 9 3 3 13 13 13 6 Essential protein Yae1, N terminal Gly-zipper_YMGG PF13441.6 OEU09845.1 - 0.0011 18.7 91.1 0.01 15.6 29.2 7.2 4 1 5 9 9 9 6 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 OEU09845.1 - 0.0026 17.6 18.5 0.0026 17.6 18.5 8.8 3 3 6 9 9 9 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OEU09845.1 - 0.0073 16.3 65.3 0.011 15.7 23.9 7.5 4 2 4 8 8 8 4 Glycine zipper PEP-utilizers_C PF02896.18 OEU09846.1 - 7.9e-53 179.5 0.0 9.7e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain V-SNARE_C PF12352.8 OEU09846.1 - 0.12 12.7 0.6 1.9 8.8 0.0 2.9 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus SET PF00856.28 OEU09847.1 - 0.00089 19.7 0.1 0.041 14.3 0.0 2.5 2 1 0 2 2 2 1 SET domain DUF3446 PF11928.8 OEU09847.1 - 0.011 16.0 4.8 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Ribosomal_L16 PF00252.18 OEU09847.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e DUF3237 PF11578.8 OEU09848.1 - 1.8e-15 57.1 0.4 1.9e-14 53.7 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Cupin_8 PF13621.6 OEU09849.1 - 7.3e-12 45.5 0.0 8.7e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU09849.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein FXR_C1 PF16096.5 OEU09850.1 - 0.87 9.8 7.5 2.4 8.4 7.5 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Gemini_AL2 PF01440.16 OEU09851.1 - 5.6e-05 23.6 0.0 0.0041 17.6 0.1 2.3 2 0 0 2 2 2 1 Geminivirus AL2 protein 7TM_GPCR_Srv PF10323.9 OEU09851.1 - 0.0014 18.1 0.7 0.0014 18.1 0.7 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv ANAPC8 PF04049.13 OEU09851.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 Orf78 PF06024.12 OEU09851.1 - 0.093 13.0 0.0 0.9 9.9 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) FAM176 PF14851.6 OEU09851.1 - 0.14 11.8 0.1 0.68 9.6 0.0 2.2 3 0 0 3 3 3 0 FAM176 family NADH_oxidored PF08040.11 OEU09851.1 - 0.16 11.7 1.1 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 MNLL subunit DUF2516 PF10724.9 OEU09851.1 - 0.28 11.5 0.0 0.28 11.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) MutL_C PF08676.11 OEU09852.1 - 9.3e-22 77.4 0.2 5.1e-20 71.7 0.2 2.2 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OEU09853.1 - 5.6e-10 39.2 0.1 8.5e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OEU09853.1 - 3.7e-07 30.6 0.2 9.2e-07 29.4 0.2 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CPP1-like PF11833.8 OEU09854.1 - 1.6e-07 31.2 0.0 4.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CK_II_beta PF01214.18 OEU09855.1 - 1.5e-25 90.1 0.0 4.5e-25 88.5 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit SNARE PF05739.19 OEU09857.1 - 3.4e-06 26.9 0.1 4.8e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 SNARE domain Rhabdo_ncap PF00945.18 OEU09857.1 - 0.015 14.2 0.0 0.016 14.1 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RIFIN PF02009.16 OEU09857.1 - 0.06 13.2 0.0 0.06 13.2 0.0 1.0 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 OEU09857.1 - 0.061 13.6 0.1 0.075 13.3 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) BTB PF00651.31 OEU09858.1 - 9.5e-19 67.7 0.5 1.8e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain SAP PF02037.27 OEU09858.1 - 0.019 14.7 0.3 0.036 13.8 0.3 1.4 1 0 0 1 1 1 0 SAP domain BTB_2 PF02214.22 OEU09858.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Thioredoxin_6 PF13848.6 OEU09858.1 - 0.057 13.3 0.7 0.14 12.0 0.5 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain Ammonium_transp PF00909.21 OEU09859.1 - 1.3e-110 369.9 26.9 1.6e-110 369.6 26.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sulfotransfer_2 PF03567.14 OEU09861.1 - 7.5e-08 32.6 11.7 0.00071 19.6 8.2 3.3 2 1 0 2 2 2 2 Sulfotransferase family TMEM223 PF14640.6 OEU09861.1 - 0.097 12.8 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 223 DHHC PF01529.20 OEU09861.1 - 0.45 10.6 3.3 0.9 9.6 3.3 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1924 PF09086.11 OEU09862.1 - 0.044 14.2 0.3 0.075 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) Metallopep PF12044.8 OEU09862.1 - 0.068 11.8 0.5 0.099 11.2 0.5 1.1 1 0 0 1 1 1 0 Putative peptidase family Presenilin PF01080.17 OEU09862.1 - 0.14 10.9 0.9 0.21 10.3 0.9 1.3 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 OEU09862.1 - 0.54 9.8 9.4 0.12 12.0 0.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ANAPC1 PF12859.7 OEU09862.1 - 4.6 7.8 6.2 0.52 10.9 1.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Fasciclin PF02469.22 OEU09863.1 - 1.4e-06 28.6 0.0 0.0018 18.5 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Fungus-induced PF10917.8 OEU09863.1 - 0.83 10.0 0.1 0.83 10.0 0.1 2.6 3 0 0 3 3 3 0 Fungus-induced protein ResIII PF04851.15 OEU09864.1 - 2.4e-21 76.5 0.1 2.6e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU09864.1 - 5.3e-20 71.8 1.8 2.7e-17 63.1 3.1 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU09864.1 - 3.6e-17 62.7 0.0 8.7e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_6 PF13516.6 OEU09865.1 - 1.8e-10 40.0 31.1 0.0024 17.8 0.2 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 OEU09865.1 - 9.4e-05 22.7 30.1 0.0023 18.3 3.7 5.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU09865.1 - 0.0025 18.1 15.7 21 6.1 0.2 6.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 OEU09865.1 - 0.0037 17.0 18.6 0.042 13.6 1.3 4.7 3 2 1 4 4 4 3 Leucine rich repeat HA PF03457.14 OEU09866.1 - 1.6e-78 259.0 28.6 8.1e-17 61.3 0.2 5.3 5 0 0 5 5 5 5 Helicase associated domain SUIM_assoc PF16619.5 OEU09866.1 - 9.6 6.4 9.2 1 9.5 4.5 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Gelsolin PF00626.22 OEU09867.1 - 7e-26 89.9 0.1 9.5e-12 44.7 0.1 3.3 3 0 0 3 3 3 3 Gelsolin repeat DUF2100 PF09873.9 OEU09867.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2100) PITH PF06201.13 OEU09868.1 - 7.3e-28 97.7 0.2 8.6e-28 97.5 0.2 1.1 1 0 0 1 1 1 1 PITH domain HPIH PF13323.6 OEU09868.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain with HPIH motif zf-MYND PF01753.18 OEU09869.1 - 9.5e-06 25.6 17.1 2.2e-05 24.5 17.1 1.7 1 0 0 1 1 1 1 MYND finger DUF3836 PF12930.7 OEU09869.1 - 1.7 8.4 8.7 0.094 12.5 1.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF3836) DUF3824 PF12868.7 OEU09870.1 - 0.011 16.4 1.1 0.011 16.4 1.1 3.0 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) DUF1917 PF08939.10 OEU09870.1 - 0.032 14.1 3.4 0.097 12.6 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) Ribosomal_L7Ae PF01248.26 OEU09871.1 - 1.7e-23 82.2 1.3 2.2e-23 81.8 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OEU09871.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 PELOTA RNA binding domain F-box-like PF12937.7 OEU09872.1 - 0.072 13.0 1.4 0.24 11.3 1.4 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OEU09872.1 - 0.084 12.8 0.2 0.24 11.3 0.2 1.8 1 0 0 1 1 1 0 F-box domain Putative_PNPOx PF01243.20 OEU09873.1 - 6.3e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HSF_DNA-bind PF00447.17 OEU09874.1 - 6.5e-22 78.0 0.0 7e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding CIA30 PF08547.12 OEU09875.1 - 1.2e-06 28.6 0.0 1.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.24 OEU09876.1 - 6.6e-20 71.4 15.6 5.3e-19 68.4 15.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU09876.1 - 1.1e-18 67.3 24.1 5.6e-13 48.5 6.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 OEU09876.1 - 0.011 15.4 0.8 0.011 15.4 0.8 2.5 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain DPM3 PF08285.11 OEU09876.1 - 0.11 12.7 2.7 8.2 6.7 0.0 3.8 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Trypsin PF00089.26 OEU09878.1 - 2.8e-15 56.7 0.3 3.1e-15 56.6 0.3 1.0 1 0 0 1 1 1 1 Trypsin Glyco_hydro_cc PF11790.8 OEU09879.1 - 3e-44 151.4 2.1 4.4e-44 150.8 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF-hand_1 PF00036.32 OEU09881.1 - 0.00023 20.5 0.3 0.00023 20.5 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OEU09881.1 - 0.0037 17.1 0.3 0.0099 15.7 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 OEU09881.1 - 0.0039 17.6 0.2 0.01 16.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU09881.1 - 0.0044 16.8 2.1 0.0051 16.7 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OEU09881.1 - 0.22 11.1 0.3 0.22 11.1 0.3 2.6 3 0 0 3 3 3 0 EF hand Putative_PNPOx PF01243.20 OEU09883.1 - 9.3e-07 29.0 0.0 2.3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4199 PF13858.6 OEU09883.1 - 0.0045 17.4 0.0 0.007 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) YfhO PF09586.10 OEU09883.1 - 2.6 6.2 5.2 3 6.0 5.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO TFIIA PF03153.13 OEU09884.1 - 0.0016 18.5 10.5 0.0021 18.1 10.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 OEU09884.1 - 0.021 14.0 30.1 0.037 13.2 30.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SRC-1 PF08832.10 OEU09884.1 - 0.038 15.0 0.3 0.038 15.0 0.3 2.9 3 0 0 3 3 3 0 Steroid receptor coactivator CPSF100_C PF13299.6 OEU09884.1 - 0.51 10.5 8.0 2.2 8.4 0.3 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Shisa PF13908.6 OEU09884.1 - 4.8 7.4 8.8 0.86 9.8 3.3 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator NRDE-2 PF08424.10 OEU09885.1 - 0.0034 16.6 2.9 0.037 13.2 0.0 2.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Ferlin_C PF16165.5 OEU09885.1 - 0.28 11.1 3.3 1.1 9.2 3.3 2.0 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 OEU09885.1 - 3.2 7.8 13.5 4.5 7.3 4.3 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Ran_BP1 PF00638.18 OEU09886.1 - 9.2e-38 129.2 0.7 1.3e-37 128.8 0.2 1.5 2 0 0 2 2 2 1 RanBP1 domain PH_15 PF17339.2 OEU09886.1 - 0.0034 17.2 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 PH domain WH1 PF00568.23 OEU09886.1 - 0.019 14.9 0.2 0.077 12.9 0.2 1.8 1 1 0 1 1 1 0 WH1 domain DUF1184 PF06683.11 OEU09887.1 - 0.037 13.5 1.5 0.041 13.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) UPF0139 PF03669.13 OEU09887.1 - 0.11 12.4 2.6 0.16 11.8 2.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) TMEMspv1-c74-12 PF11044.8 OEU09887.1 - 0.32 11.0 0.1 0.32 11.0 0.1 1.9 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GBV-C_env PF12786.7 OEU09887.1 - 9.5 4.8 8.6 13 4.4 8.6 1.4 1 1 0 1 1 1 0 GB virus C genotype envelope PRC2_HTH_1 PF18118.1 OEU09888.1 - 0.057 14.2 2.7 0.22 12.4 0.1 2.8 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain DEAD PF00270.29 OEU09889.1 - 2.5e-10 40.4 0.1 9.4e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU09889.1 - 1.1e-06 29.0 0.0 4.2e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Spem1 PF15670.5 OEU09889.1 - 0.092 12.3 5.4 0.26 10.8 5.4 1.8 1 0 0 1 1 1 0 Spermatid maturation protein 1 CNDH2_M PF16869.5 OEU09889.1 - 0.15 12.7 11.9 0.13 13.0 8.2 2.9 2 0 0 2 2 2 0 PF16858 Cwf_Cwc_15 PF04889.12 OEU09889.1 - 2.5 7.8 38.8 2.9 7.6 14.2 4.4 4 0 0 4 4 4 0 Cwf15/Cwc15 cell cycle control protein Fasciclin PF02469.22 OEU09890.1 - 9.5e-21 74.4 0.0 1.6e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Lipase_3 PF01764.25 OEU09891.1 - 3e-06 27.2 0.0 9.7e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) RPN2_C PF18004.1 OEU09891.1 - 0.21 11.5 16.7 0.025 14.5 1.8 3.0 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain SARAF PF06682.12 OEU09892.1 - 0.042 13.5 10.1 0.048 13.3 2.7 2.7 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Attachment_P66 PF11263.8 OEU09893.1 - 0.29 10.3 0.4 0.34 10.1 0.4 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 betaPIX_CC PF16523.5 OEU09895.1 - 0.48 10.3 6.1 13 5.7 0.1 3.0 3 0 0 3 3 3 0 betaPIX coiled coil PRORP PF16953.5 OEU09898.1 - 4.5e-26 91.8 8.5 9.9e-26 90.7 8.5 1.6 1 0 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 OEU09898.1 - 3.3e-20 72.4 5.2 1.7e-08 34.1 0.0 4.2 4 0 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 OEU09898.1 - 2.3e-08 34.0 2.9 5.7e-08 32.7 1.4 2.3 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain PPR_3 PF13812.6 OEU09898.1 - 0.002 18.1 0.6 0.0074 16.4 0.0 2.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 OEU09898.1 - 0.02 15.1 0.3 2.3 8.6 0.0 3.2 2 0 0 2 2 2 0 PPR repeat CDH1_2_SANT_HL1 PF18375.1 OEU09898.1 - 0.082 13.6 0.5 0.082 13.6 0.5 3.5 4 0 0 4 4 4 0 CDH1/2 SANT-Helical linker 1 Skp1 PF01466.19 OEU09899.1 - 6.3e-28 96.6 0.2 1.2e-27 95.8 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OEU09899.1 - 3.3e-13 49.6 6.4 3.5e-11 43.1 6.4 2.4 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain KIND PF16474.5 OEU09899.1 - 0.0063 16.4 0.5 0.0095 15.9 0.5 1.3 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain Cwf_Cwc_15 PF04889.12 OEU09899.1 - 0.02 14.6 4.7 0.023 14.4 4.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 OEU09899.1 - 0.026 13.9 4.0 0.037 13.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) BTB PF00651.31 OEU09899.1 - 0.035 14.3 0.8 0.45 10.8 0.1 2.1 1 1 1 2 2 2 0 BTB/POZ domain DUF1450 PF07293.11 OEU09899.1 - 0.08 12.8 0.2 0.29 11.0 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1450) RMI1_C PF16099.5 OEU09899.1 - 0.098 12.5 0.1 0.24 11.3 0.1 1.7 1 1 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold TBX PF12598.8 OEU09899.1 - 0.13 13.1 4.5 0.28 12.0 4.5 1.6 1 0 0 1 1 1 0 T-box transcription factor NOA36 PF06524.12 OEU09899.1 - 0.59 9.4 5.5 0.85 8.9 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 OEU09899.1 - 3.3 8.2 14.5 6.3 7.3 14.3 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain FBA PF04300.13 OEU09900.1 - 1.6e-06 28.0 2.3 0.0052 16.5 0.4 3.1 2 1 0 2 2 2 2 F-box associated region zf-RING_11 PF17123.5 OEU09900.1 - 6.1e-05 22.7 0.2 6.1e-05 22.7 0.2 3.8 4 0 0 4 4 4 2 RING-like zinc finger zf-rbx1 PF12678.7 OEU09900.1 - 0.025 14.8 3.8 0.025 14.8 3.8 3.5 4 2 0 4 4 4 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OEU09900.1 - 0.14 12.5 0.2 0.14 12.5 0.2 5.4 6 1 0 6 6 6 0 Ring finger domain Trypan_PARP PF05887.11 OEU09900.1 - 0.46 10.5 3.3 1.3 9.1 3.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRXRR PF14239.6 OEU09903.1 - 0.0028 17.5 3.0 0.0042 17.0 3.0 1.2 1 0 0 1 1 1 1 RRXRR protein Dirigent PF03018.14 OEU09904.1 - 0.013 15.3 0.3 0.033 14.0 0.2 1.7 2 0 0 2 2 2 0 Dirigent-like protein Cauli_VI PF01693.16 OEU09905.1 - 3.8e-17 62.3 0.3 7.7e-17 61.3 0.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 OEU09905.1 - 5.3e-08 32.7 2.1 0.075 12.8 0.0 3.6 1 1 2 3 3 3 3 Reverse transcriptase-like Pro_sub2 PF18513.1 OEU09905.1 - 0.031 14.5 0.1 0.084 13.1 0.1 1.7 1 0 0 1 1 1 0 Prodomain subtilisin 2 Mei5_like PF17021.5 OEU09907.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.3 1 1 1 2 2 2 0 Putative double-strand recombination repair-like GT-D PF08759.11 OEU09907.1 - 0.18 11.4 3.4 0.23 11.1 2.3 1.7 1 1 0 1 1 1 0 Glycosyltransferase GT-D fold PT PF04886.12 OEU09908.1 - 1.5e-11 43.6 89.7 0.00037 20.0 28.2 5.6 2 1 2 4 4 4 3 PT repeat YadA_head PF05658.14 OEU09908.1 - 3.7e-08 33.6 0.6 7.1e-05 23.1 0.1 5.5 5 0 0 5 5 5 2 Head domain of trimeric autotransporter adhesin UspA1_rep PF18792.1 OEU09908.1 - 0.04 14.4 0.3 0.04 14.4 0.3 17.2 17 1 0 17 17 17 0 Ubiquitous surface protein adhesin repeat DED PF01335.21 OEU09908.1 - 0.067 13.5 1.2 0.3 11.4 0.5 2.1 2 0 0 2 2 2 0 Death effector domain DLP_helical PF18709.1 OEU09908.1 - 5.8 6.0 11.4 2.4 7.3 4.2 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain FAD-oxidase_C PF02913.19 OEU09909.1 - 6.4e-51 173.4 0.0 9.2e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OEU09909.1 - 2.2e-31 108.4 0.0 4.3e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF373 PF04123.13 OEU09910.1 - 0.0062 16.0 4.3 0.0062 16.0 4.3 2.6 2 2 0 2 2 2 1 Domain of unknown function (DUF373) Alg14 PF08660.11 OEU09910.1 - 0.055 13.4 1.0 3.2 7.7 0.1 2.7 2 1 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like KR PF08659.10 OEU09910.1 - 0.057 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 KR domain RFamide_26RFa PF11109.8 OEU09910.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 HATPase_c_3 PF13589.6 OEU09911.1 - 0.0021 17.9 5.2 0.005 16.7 0.2 3.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nitroreductase PF00881.24 OEU09912.1 - 1.3e-06 28.6 0.0 0.06 13.4 0.0 2.3 2 0 0 2 2 2 2 Nitroreductase family Urate_ox_N PF06181.11 OEU09912.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Urate oxidase N-terminal HCO3_cotransp PF00955.21 OEU09913.1 - 3.3e-79 267.0 11.3 4.1e-47 161.2 0.0 2.2 1 1 1 2 2 2 2 HCO3- transporter family Inositol_P PF00459.25 OEU09914.1 - 3.7e-56 190.6 0.0 4.7e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 OEU09914.1 - 0.011 15.3 0.1 0.034 13.6 0.0 1.9 1 1 1 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain Cmc1 PF08583.10 OEU09915.1 - 0.039 14.0 1.1 0.039 14.0 1.1 3.2 3 1 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like YbgS PF13985.6 OEU09915.1 - 0.55 10.5 5.7 1.2 9.4 5.7 1.6 1 1 0 1 1 1 0 YbgS-like protein TFIIA PF03153.13 OEU09916.1 - 0.094 12.7 22.5 0.12 12.4 22.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MOZ_SAS PF01853.18 OEU09917.1 - 8.6e-82 273.1 1.0 1.2e-81 272.7 1.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OEU09917.1 - 2.2e-11 43.2 16.9 1.8e-06 27.5 6.3 3.5 3 0 0 3 3 3 2 MYST family zinc finger domain IF2_N PF04760.15 OEU09917.1 - 0.0035 17.1 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region NUDIX PF00293.28 OEU09917.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Cyt-b5 PF00173.28 OEU09918.1 - 5.9e-13 48.8 0.0 6.1e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 5_3_exonuc_N PF02739.16 OEU09919.1 - 1.9e-37 128.6 0.1 2.4e-36 125.1 0.0 2.5 2 1 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 OEU09919.1 - 3e-28 98.2 2.2 2e-27 95.6 0.1 2.6 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OEU09919.1 - 0.0021 18.6 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain SPX PF03105.19 OEU09919.1 - 0.0023 17.9 0.0 0.0023 17.9 0.0 2.7 1 1 1 2 2 2 1 SPX domain HHH_2 PF12826.7 OEU09919.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF3913 PF13052.6 OEU09919.1 - 0.059 13.6 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) VitD-bind_III PF09164.10 OEU09919.1 - 0.62 10.1 3.1 1.9 8.6 0.3 2.4 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF3381 PF11861.8 OEU09920.1 - 2.6 7.8 41.6 2.1 8.1 1.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) Nop53 PF07767.11 OEU09920.1 - 7.8 5.8 46.5 3.6 6.9 4.4 3.2 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) DUF3663 PF12404.8 OEU09922.1 - 0.15 12.1 0.2 4.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Peptidase Pkinase PF00069.25 OEU09923.1 - 3.3e-62 210.2 0.0 3.9e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU09923.1 - 5.7e-31 107.7 0.0 7.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU09923.1 - 0.0026 16.6 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU09923.1 - 0.024 14.6 0.0 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OEU09923.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family cNMP_binding PF00027.29 OEU09924.1 - 1.6e-36 124.3 0.1 1.4e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Bclt PF15318.6 OEU09925.1 - 0.011 15.6 0.7 2.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis FAD_binding_3 PF01494.19 OEU09926.1 - 1.5e-15 57.4 2.4 2.5e-07 30.3 0.2 3.2 2 1 1 3 3 3 3 FAD binding domain SE PF08491.10 OEU09926.1 - 1.6e-05 24.1 0.0 0.0001 21.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 OEU09926.1 - 0.011 14.6 0.2 1.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 OEU09926.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU09926.1 - 0.075 12.2 0.0 0.93 8.7 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPBP PF02517.16 OEU09927.1 - 3.1e-20 72.3 3.8 3.1e-20 72.3 3.8 1.6 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF1995 PF09353.10 OEU09928.1 - 7.4e-17 62.0 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) LRR_8 PF13855.6 OEU09930.1 - 1e-32 111.7 17.7 7.3e-10 38.5 3.3 5.2 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OEU09930.1 - 7.8e-22 77.0 22.4 2.9e-05 24.3 2.1 7.1 3 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU09930.1 - 3.2e-17 60.4 14.9 0.028 14.9 0.1 9.7 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.6 OEU09930.1 - 1.1e-09 37.6 14.5 6.4 7.1 0.0 8.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.6 OEU09930.1 - 0.00052 19.6 3.5 0.92 9.0 0.0 3.5 3 1 1 4 4 4 3 Leucine-rich repeat DSPc PF00782.20 OEU09931.1 - 7.9e-06 25.7 0.0 1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OEU09931.1 - 1.8e-05 24.5 0.0 2.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Mo25 PF08569.11 OEU09932.1 - 0.0015 17.9 0.0 2 7.7 0.0 2.7 1 1 2 3 3 3 2 Mo25-like VirE PF05272.11 OEU09932.1 - 0.021 14.6 0.3 26 4.5 0.0 4.1 3 1 2 5 5 5 0 Virulence-associated protein E GP67 PF17634.2 OEU09932.1 - 0.034 14.5 12.7 3.8 8.0 0.1 6.0 6 0 0 6 6 6 0 Gene product 67 Myb_Cef PF11831.8 OEU09932.1 - 0.18 11.3 2.4 10 5.6 0.0 2.8 2 1 1 3 3 3 0 pre-mRNA splicing factor component RIIa PF02197.17 OEU09932.1 - 0.28 10.9 1.8 1.6e+02 2.1 0.0 4.6 6 0 0 6 6 6 0 Regulatory subunit of type II PKA R-subunit MOSC PF03473.17 OEU09932.1 - 0.33 11.0 1.6 35 4.4 0.0 3.5 2 1 1 4 4 4 0 MOSC domain ENTH PF01417.20 OEU09933.1 - 0.028 14.4 0.6 0.03 14.4 0.6 1.0 1 0 0 1 1 1 0 ENTH domain DUF1168 PF06658.12 OEU09934.1 - 0.0025 17.6 0.5 0.0037 17.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Macoilin PF09726.9 OEU09934.1 - 0.75 8.3 9.4 0.79 8.2 9.4 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 OEU09934.1 - 3.3 4.7 9.9 3.3 4.7 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RCC1 PF00415.18 OEU09935.1 - 6.5e-19 68.3 7.1 2.5e-06 28.0 0.0 4.7 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU09935.1 - 3.3e-15 55.4 4.8 7.5e-06 25.6 0.1 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Gp_dh_C PF02800.20 OEU09937.1 - 6.9e-66 220.7 0.0 1.1e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU09937.1 - 7.7e-29 100.0 0.0 1.6e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DnaJ PF00226.31 OEU09938.1 - 2.5e-10 40.3 0.1 4.6e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2076 PF09849.9 OEU09938.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) TRAPPC9-Trs120 PF08626.11 OEU09938.1 - 2.3 5.4 4.5 3.3 4.9 4.5 1.2 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Bax1-I PF01027.20 OEU09939.1 - 4.2e-25 88.8 8.0 4.6e-25 88.7 8.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MARVEL PF01284.23 OEU09939.1 - 0.015 15.3 6.1 0.026 14.6 6.1 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF2070 PF09843.9 OEU09939.1 - 0.14 10.4 5.6 0.2 9.9 5.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) IPTL-CTERM PF18203.1 OEU09939.1 - 1.4 8.9 9.6 0.28 11.1 3.4 2.7 2 0 0 2 2 2 0 IPTL-CTERM motif DUF3093 PF11292.8 OEU09939.1 - 9 6.6 6.7 1.7 8.9 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3093) Clat_adaptor_s PF01217.20 OEU09940.1 - 1.2e-46 158.2 1.3 1.4e-46 157.9 1.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Radical_SAM PF04055.21 OEU09941.1 - 0.0013 19.1 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF572 PF04502.13 OEU09941.1 - 0.065 12.8 2.9 0.091 12.4 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Abhydrolase_1 PF00561.20 OEU09942.1 - 2.3e-15 56.9 1.2 1.7e-14 54.1 1.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU09942.1 - 4.2e-10 39.3 0.0 0.0017 17.7 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU09942.1 - 4e-05 24.3 0.0 5.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OEU09942.1 - 0.086 12.6 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ndr PF03096.14 OEU09942.1 - 0.099 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family SR-25 PF10500.9 OEU09942.1 - 0.93 9.1 4.7 1.7 8.2 4.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Redoxin PF08534.10 OEU09944.1 - 2.4e-20 72.8 0.1 5.3e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 OEU09944.1 - 8.1e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Gln-synt_C PF00120.24 OEU09945.1 - 5e-20 71.8 0.0 2.6e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OEU09945.1 - 9e-12 44.6 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain AOX PF01786.17 OEU09946.1 - 6e-25 88.1 0.0 9e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Alternative oxidase Rrp44_CSD1 PF17216.3 OEU09946.1 - 0.13 12.0 1.9 0.34 10.6 1.9 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain DUF3494 PF11999.8 OEU09947.1 - 5.6e-56 189.5 15.6 8.5e-56 188.9 15.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Glyco_transf_34 PF05637.12 OEU09948.1 - 0.041 13.6 0.1 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Cut12 PF11500.8 OEU09948.1 - 4.2 7.3 11.5 0.48 10.4 4.2 2.3 1 1 1 2 2 2 0 Spindle pole body formation-associated protein Pan_kinase PF03309.14 OEU09949.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Type III pantothenate kinase Glyco_hydro_10 PF00331.20 OEU09950.1 - 3.5e-74 249.8 0.0 4.9e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CDC45 PF02724.14 OEU09950.1 - 0.11 10.8 2.2 0.17 10.1 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RNase_T PF00929.24 OEU09951.1 - 5.4e-10 40.1 0.0 7.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OEU09951.1 - 0.087 12.5 0.1 0.19 11.4 0.1 1.8 1 1 0 1 1 1 0 3'-5' exonuclease Leo1 PF04004.13 OEU09955.1 - 1.1e-23 83.9 0.5 2e-23 83.0 0.5 1.4 1 0 0 1 1 1 1 Leo1-like protein DUF4196 PF13846.6 OEU09955.1 - 0.0007 19.8 7.7 0.0007 19.8 7.7 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4196) DUF4809 PF16067.5 OEU09955.1 - 0.11 12.6 0.4 0.21 11.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) UCH PF00443.29 OEU09956.1 - 0.097 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CSN8_PSD8_EIF3K PF10075.9 OEU09957.1 - 0.00016 21.7 0.1 0.00032 20.7 0.1 1.6 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Eapp_C PF10238.9 OEU09958.1 - 3.8e-34 117.9 13.5 1.4e-33 116.1 12.8 2.1 1 1 0 1 1 1 1 E2F-associated phosphoprotein Sporozoite_P67 PF05642.11 OEU09958.1 - 2 6.4 9.7 3 5.8 1.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PPR PF01535.20 OEU09959.1 - 0.013 15.7 7.2 2.1 8.8 0.0 5.1 5 0 0 5 5 5 0 PPR repeat PPR_2 PF13041.6 OEU09959.1 - 0.018 15.2 1.1 1.7 8.9 0.0 3.9 4 1 0 4 4 4 0 PPR repeat family Mad3_BUB1_I_2 PF17014.5 OEU09959.1 - 0.13 12.3 0.1 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein SPX PF03105.19 OEU09960.1 - 5.8e-17 62.7 17.9 3.7e-08 33.7 3.9 2.9 1 1 1 2 2 2 2 SPX domain FAD_syn PF06574.12 OEU09960.1 - 0.0007 19.5 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 FAD synthetase CTP_transf_like PF01467.26 OEU09960.1 - 0.0022 18.2 0.6 0.057 13.6 0.1 2.8 2 1 1 3 3 3 1 Cytidylyltransferase-like Aminotran_4 PF01063.19 OEU09961.1 - 4.2e-23 82.4 0.0 4.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Kri1_C PF12936.7 OEU09962.1 - 3.7e-23 81.5 4.7 3.7e-23 81.5 4.7 5.7 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 OEU09962.1 - 6e-19 68.5 14.5 6e-19 68.5 14.5 8.4 5 2 3 8 8 8 1 KRI1-like family Sarcoglycan_2 PF05510.13 OEU09963.1 - 1 8.1 3.2 6.2 5.5 0.1 2.2 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Methyltransf_23 PF13489.6 OEU09964.1 - 1.5e-10 41.1 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU09964.1 - 1.4e-06 28.1 0.0 2.3e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU09964.1 - 1e-05 26.1 0.0 1.9e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU09964.1 - 0.00048 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU09964.1 - 0.012 16.2 0.0 0.03 15.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain SelR PF01641.18 OEU09965.1 - 0.0011 19.0 0.6 0.0045 17.1 0.6 2.0 1 1 0 1 1 1 1 SelR domain Pyrid_oxidase_2 PF13883.6 OEU09966.1 - 1.9e-41 141.9 0.0 2.4e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_S28 PF05577.12 OEU09967.1 - 3.9e-47 161.0 0.0 6e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 OEU09967.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ac76 PF05814.11 OEU09968.1 - 0.014 15.4 3.3 0.014 15.4 1.7 1.9 1 1 1 2 2 2 0 Orf76 (Ac76) UFD1 PF03152.14 OEU09970.1 - 8.3e-43 145.8 0.3 8.3e-37 126.3 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Smr PF01713.21 OEU09971.1 - 0.0087 16.4 0.1 0.022 15.1 0.1 1.7 1 0 0 1 1 1 1 Smr domain Laminin_II PF06009.12 OEU09971.1 - 0.02 14.9 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Med31 PF05669.12 OEU09972.1 - 6e-26 90.3 5.6 7.6e-26 90.0 5.6 1.1 1 0 0 1 1 1 1 SOH1 CCDC23 PF15674.5 OEU09972.1 - 0.072 13.1 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 RRM_1 PF00076.22 OEU09973.1 - 0.0078 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 OEU09974.1 - 8.4e-42 141.0 6.1 9e-22 76.8 0.1 3.8 3 1 1 4 4 4 3 Mitochondrial carrier protein Macoilin PF09726.9 OEU09974.1 - 2.3 6.7 4.8 2.8 6.4 4.8 1.1 1 0 0 1 1 1 0 Macoilin family RRF_GI PF12614.8 OEU09975.1 - 0.0052 16.9 1.0 0.0052 16.9 1.0 4.1 3 0 0 3 3 3 1 Ribosome recycling factor DUF3563 PF12086.8 OEU09975.1 - 0.83 9.4 4.7 4.1 7.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3563) DUF3188 PF11384.8 OEU09976.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF846 PF05832.12 OEU09977.1 - 1e-51 174.6 11.9 1.2e-51 174.4 11.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 OEU09977.1 - 4.5 8.1 8.5 2.7 8.8 3.8 2.2 1 1 1 2 2 2 0 Transmembrane family 220, helix Histone PF00125.24 OEU09978.1 - 6.3e-54 181.9 1.9 7e-54 181.7 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OEU09978.1 - 0.00012 22.7 1.4 0.00014 22.5 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OEU09978.1 - 0.00055 20.3 0.0 0.00084 19.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OEU09978.1 - 0.00072 19.7 0.6 0.001 19.2 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OEU09978.1 - 0.032 14.3 0.1 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 OEU09978.1 - 0.035 14.4 0.1 0.072 13.4 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FRG2 PF15315.6 OEU09978.1 - 0.098 12.8 1.1 0.12 12.6 1.1 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 TTD PF12148.8 OEU09979.1 - 0.00077 19.4 0.8 0.0053 16.6 0.0 2.5 3 0 0 3 3 3 1 Tandem tudor domain within UHRF1 IQ PF00612.27 OEU09979.1 - 0.14 12.0 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif SBDS PF01172.18 OEU09980.1 - 1.3e-31 108.5 0.7 1.8e-31 108.0 0.7 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 OEU09980.1 - 5.9e-18 65.0 0.3 1.3e-17 63.9 0.3 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain ADH_zinc_N_2 PF13602.6 OEU09980.1 - 0.097 13.7 0.0 0.17 12.9 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF587 PF04532.12 OEU09981.1 - 0.096 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) XRN_N PF03159.18 OEU09982.1 - 1.3 8.4 5.7 3.2 7.1 5.7 1.6 1 1 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus E1-E2_ATPase PF00122.20 OEU09985.1 - 2.5e-41 141.2 1.6 9.9e-41 139.2 0.2 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OEU09985.1 - 2.6e-38 131.5 2.7 3.2e-38 131.3 0.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OEU09985.1 - 8.7e-17 61.0 0.0 5.3e-16 58.5 0.0 2.2 1 1 1 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OEU09985.1 - 6.2e-16 59.3 1.0 3.1e-15 57.0 1.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OEU09985.1 - 1.9e-11 43.5 0.0 4.8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OEU09985.1 - 0.095 12.4 0.7 0.25 11.0 0.7 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Jagunal PF07086.12 OEU09986.1 - 0.001 19.1 0.1 0.0013 18.9 0.1 1.1 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis CRAL_TRIO PF00650.20 OEU09987.1 - 1e-13 51.3 0.3 1.7e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU09987.1 - 7.2e-05 23.0 0.1 0.00011 22.4 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PDZ PF00595.24 OEU09987.1 - 0.001 19.4 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU09987.1 - 0.0035 17.2 0.1 0.0085 15.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain SnoaL_3 PF13474.6 OEU09988.1 - 1.1e-16 61.1 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OEU09988.1 - 2.4e-08 34.3 0.0 3.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OEU09988.1 - 2.9e-07 31.1 0.0 4.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 OEU09988.1 - 0.01 16.0 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like domain tRNA-synt_2b PF00587.25 OEU09989.1 - 3.1e-31 108.7 0.1 4.6e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OEU09989.1 - 9.5e-22 77.0 0.6 1.6e-21 76.2 0.6 1.4 1 0 0 1 1 1 1 Anticodon binding domain Inhibitor_I29 PF08246.12 OEU09990.1 - 0.00011 22.6 1.2 0.00033 21.0 1.2 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) UAA PF08449.11 OEU09991.1 - 2.6e-42 145.1 25.4 5.1e-42 144.1 25.4 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 OEU09991.1 - 2.1e-10 40.4 13.7 2.9e-10 40.0 13.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 OEU09991.1 - 4.7e-07 29.3 3.0 4.7e-07 29.3 3.0 3.1 1 1 2 3 3 3 1 Purine nucleobase transmembrane transport EamA PF00892.20 OEU09991.1 - 0.00019 21.6 26.0 0.023 14.9 7.1 3.1 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 OEU09991.1 - 0.0043 16.0 5.5 0.0043 16.0 5.5 2.1 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Phage_holin_2_3 PF16080.5 OEU09991.1 - 0.31 10.8 2.1 2 8.2 0.2 3.1 2 0 0 2 2 2 0 Bacteriophage holin family HP1 ENOD93 PF03386.14 OEU09991.1 - 1.8 8.5 5.8 34 4.4 0.1 3.4 2 1 1 3 3 3 0 Early nodulin 93 ENOD93 protein FeoB_associated PF12669.7 OEU09991.1 - 9.1 6.8 7.4 0.55 10.7 0.2 2.8 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein PH PF00169.29 OEU09992.1 - 0.096 13.2 0.0 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 PH domain hnRNP_Q_AcD PF18360.1 OEU09992.1 - 0.12 12.3 0.2 8.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain CCDC53 PF10152.9 OEU09993.1 - 7.1e-18 65.5 20.7 9e-06 26.2 0.2 5.6 3 1 2 5 5 5 3 Subunit CCDC53 of WASH complex WH2 PF02205.20 OEU09993.1 - 0.001 18.8 75.8 2 8.4 3.3 9.9 7 2 2 9 9 9 8 WH2 motif DUF2884 PF11101.8 OEU09993.1 - 5.1 6.5 12.3 35 3.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2884) DUF963 PF06131.11 OEU09994.1 - 0.56 9.7 4.8 0.25 10.8 0.6 2.7 3 0 0 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) AIRS_C PF02769.22 OEU09995.1 - 5.3e-16 59.1 0.9 5.5e-15 55.8 0.2 2.5 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 OEU09995.1 - 1.4e-08 35.3 0.1 3.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Terminase_4 PF05119.12 OEU09995.1 - 0.076 13.5 0.2 0.39 11.2 0.1 2.0 2 0 0 2 2 2 0 Phage terminase, small subunit DUF4239 PF14023.6 OEU09996.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Glyco_hydro81C PF17652.1 OEU09997.1 - 6.3e-69 232.9 4.6 1e-68 232.1 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OEU09997.1 - 1.7e-35 122.7 0.3 3.6e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain LPP20 PF02169.16 OEU09997.1 - 0.098 13.0 2.7 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 LPP20 lipoprotein zf-CHY PF05495.12 OEU09998.1 - 2.8 8.5 6.7 7.6 7.1 1.5 2.6 2 0 0 2 2 2 0 CHY zinc finger RRM_1 PF00076.22 OEU10000.1 - 2.1e-15 56.3 0.0 2.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelR PF01641.18 OEU10001.1 - 1.5e-38 131.6 0.1 3e-38 130.6 0.1 1.5 1 0 0 1 1 1 1 SelR domain DNA_RNApol_7kD PF03604.13 OEU10001.1 - 0.0067 16.1 2.2 0.99 9.1 0.5 2.3 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit Yippee-Mis18 PF03226.14 OEU10001.1 - 0.023 14.9 0.0 0.068 13.4 0.0 1.9 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_C2HC_14 PF18574.1 OEU10001.1 - 0.37 10.6 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 C2HC Zing finger domain HNF-1_N PF04814.13 OEU10002.1 - 0.21 12.2 4.1 4.4 7.9 0.0 2.6 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Patatin PF01734.22 OEU10003.1 - 0.00012 22.3 0.2 0.00021 21.5 0.2 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Pilin PF00114.19 OEU10003.1 - 0.03 15.2 0.1 0.061 14.3 0.1 1.6 1 1 0 1 1 1 0 Pilin (bacterial filament) DUF3139 PF11337.8 OEU10003.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) RNase_P_Rpp14 PF01900.19 OEU10004.1 - 0.0067 16.7 0.0 0.0077 16.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Seipin PF06775.14 OEU10004.1 - 0.072 13.2 0.0 0.076 13.1 0.0 1.0 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) Tcp11 PF05794.13 OEU10005.1 - 7.7e-07 28.6 0.2 9.7e-06 24.9 0.2 2.4 1 1 0 1 1 1 1 T-complex protein 11 Apis_Csd PF11671.8 OEU10006.1 - 8.7 6.3 11.2 0.79 9.7 2.3 2.5 2 0 0 2 2 2 0 Complementary sex determiner protein SAICAR_synt PF01259.18 OEU10007.1 - 1.2e-71 241.2 0.0 1.4e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Aminotran_5 PF00266.19 OEU10008.1 - 4.8e-35 121.2 0.0 5.7e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Branch PF02485.21 OEU10009.1 - 2.3e-09 37.2 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2407 PF10302.9 OEU10009.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SNF2_N PF00176.23 OEU10010.1 - 1.3e-55 188.6 0.0 1.8e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU10010.1 - 2.1e-14 53.8 0.0 5.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU10010.1 - 3.5e-09 36.9 0.0 3.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU10010.1 - 5.9e-08 32.2 0.0 1.7e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU10010.1 - 3.2e-06 27.0 0.0 7.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF819 PF05684.12 OEU10011.1 - 3.3e-76 256.8 21.0 3.9e-76 256.5 21.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) SWIB PF02201.18 OEU10013.1 - 5.9e-10 38.9 0.1 1.1e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain EF-hand_1 PF00036.32 OEU10015.1 - 3.2e-08 32.6 1.1 0.0012 18.2 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU10015.1 - 8.7e-08 31.5 1.5 0.018 14.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OEU10015.1 - 7.2e-07 29.6 0.4 2.9e-06 27.7 0.4 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU10015.1 - 8.1e-06 25.1 0.9 0.0029 17.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OEU10015.1 - 0.21 11.5 1.4 10 6.0 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair Sybindin PF04099.12 OEU10016.1 - 3.4e-38 130.8 0.0 4e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OEU10016.1 - 6.4e-08 32.8 0.0 6.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MitMem_reg PF13012.6 OEU10017.1 - 1.5e-27 96.2 0.5 2.4e-27 95.6 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OEU10017.1 - 1.4e-25 89.5 0.0 2.8e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BT1 PF03092.16 OEU10017.1 - 0.11 10.8 0.3 0.17 10.1 0.3 1.3 1 0 0 1 1 1 0 BT1 family IMS PF00817.20 OEU10018.1 - 1e-31 110.0 0.4 2.1e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.8 OEU10018.1 - 2.8e-06 27.3 0.0 2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif IMS_C PF11799.8 OEU10018.1 - 7.2e-06 26.7 0.1 3.5e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Rad51 PF08423.11 OEU10019.1 - 3.5e-12 46.1 0.0 8e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 Rad51 DUF5066 PF16728.5 OEU10019.1 - 0.06 12.7 1.8 1.3 8.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5066) Hep_59 PF07052.11 OEU10019.1 - 2.4 9.0 12.8 0.17 12.7 0.7 2.8 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Peptidase_M16_M PF16187.5 OEU10020.1 - 1.1e-44 152.8 0.0 4.8e-42 144.2 0.0 2.4 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OEU10020.1 - 5.7e-34 117.3 0.0 4.6e-33 114.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU10020.1 - 3.8e-26 92.2 0.0 1.4e-19 70.8 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Complex1_LYR PF05347.15 OEU10021.1 - 0.0091 16.0 3.3 0.12 12.5 3.3 2.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OEU10021.1 - 0.01 16.5 0.2 0.037 14.8 0.0 2.1 2 0 0 2 2 2 0 Complex1_LYR-like rve_3 PF13683.6 OEU10021.1 - 0.11 12.3 0.2 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain HhH-GPD PF00730.25 OEU10022.1 - 0.0004 20.8 0.0 0.00098 19.6 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TPR_12 PF13424.6 OEU10023.1 - 2.6e-88 290.3 33.8 2.8e-14 53.2 0.3 10.0 7 2 4 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10023.1 - 2.9e-61 200.9 25.4 1.4e-06 27.9 0.1 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_10 PF13374.6 OEU10023.1 - 1.8e-56 186.6 28.2 5.6e-07 29.2 0.2 13.7 13 1 0 13 13 13 12 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10023.1 - 3.9e-53 173.3 25.0 0.00013 21.8 0.0 13.6 14 0 0 14 14 13 10 Tetratricopeptide repeat TPR_8 PF13181.6 OEU10023.1 - 4.1e-50 163.8 28.7 2.5e-06 27.2 0.0 12.5 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10023.1 - 5.1e-41 135.7 22.2 0.00021 21.1 0.0 11.9 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU10023.1 - 1.5e-28 100.2 7.2 1e-14 54.7 1.0 5.1 3 1 1 5 5 5 3 MalT-like TPR region TPR_11 PF13414.6 OEU10023.1 - 6.4e-27 93.0 25.1 5.4e-05 22.8 0.5 11.6 11 1 0 11 11 11 7 TPR repeat TPR_16 PF13432.6 OEU10023.1 - 3e-20 72.6 1.0 0.66 10.7 0.0 11.3 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 OEU10023.1 - 1.4e-19 69.1 1.0 5 8.2 0.0 11.1 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10023.1 - 1.9e-16 59.5 15.9 0.93 10.3 0.1 12.3 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 OEU10023.1 - 2.5e-11 43.1 8.9 0.68 10.4 0.0 10.1 10 0 0 10 10 10 1 Tetratricopeptide repeat SNAP PF14938.6 OEU10023.1 - 6.5e-11 42.2 5.3 0.015 14.8 4.4 5.3 3 2 1 5 5 5 3 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 OEU10023.1 - 1.9e-08 34.7 5.1 0.52 10.9 0.0 7.0 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU10023.1 - 3.2e-07 30.4 4.2 21 5.3 0.0 8.2 6 3 2 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 OEU10023.1 - 4.8e-07 29.6 7.0 1.7 9.1 0.1 7.5 7 1 1 8 8 8 1 PPR repeat MIT PF04212.18 OEU10023.1 - 1.5e-06 28.2 11.0 0.99 9.5 0.0 7.2 7 1 1 8 8 8 3 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 OEU10023.1 - 0.00019 21.2 14.2 0.78 9.4 0.0 6.2 4 1 2 7 7 7 2 26S proteasome subunit RPN7 TPR_4 PF07721.14 OEU10023.1 - 0.0009 19.7 0.1 0.59 10.9 0.0 4.8 6 0 0 6 6 3 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU10023.1 - 0.0078 15.7 0.6 21 4.5 0.0 4.7 4 1 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like DUF5475 PF17569.2 OEU10023.1 - 0.043 14.1 0.3 0.47 10.8 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5475) ANAPC5 PF12862.7 OEU10023.1 - 0.057 13.5 15.0 13 5.9 0.0 6.8 4 3 1 5 5 4 0 Anaphase-promoting complex subunit 5 HTH_Bact PF18768.1 OEU10023.1 - 0.25 11.0 4.9 0.99 9.0 0.1 4.2 4 1 0 4 4 4 0 Helix-turn-helix bacterial domain PPR_2 PF13041.6 OEU10023.1 - 9.2 6.5 12.0 34 4.7 0.0 6.4 9 1 1 10 10 7 0 PPR repeat family Nucleoside_tran PF01733.18 OEU10024.1 - 5.1e-27 95.1 27.9 4.9e-24 85.3 7.7 3.8 3 1 1 4 4 4 3 Nucleoside transporter DUF3377 PF11857.8 OEU10024.1 - 0.012 15.5 1.4 0.026 14.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 OEU10024.1 - 1.1 9.2 7.2 0.55 10.1 3.1 2.6 2 0 0 2 2 2 0 TMEM154 protein family DUF2663 PF10864.8 OEU10025.1 - 0.076 13.4 0.4 0.19 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) ABC2_membrane_5 PF13346.6 OEU10025.1 - 0.48 9.9 7.5 0.7 9.4 7.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4181 PF13789.6 OEU10025.1 - 0.64 10.3 3.2 3.7 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Nucleoside_tran PF01733.18 OEU10026.1 - 2.4e-31 109.3 0.5 2.9e-31 109.0 0.5 1.0 1 0 0 1 1 1 1 Nucleoside transporter Insulin_TMD PF17870.1 OEU10026.1 - 0.14 12.3 0.3 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF1295 PF06966.12 OEU10027.1 - 1.8e-28 99.7 11.8 1.2e-18 67.5 4.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) PP-binding PF00550.25 OEU10028.1 - 1.7e-16 60.3 1.1 2.2e-16 59.9 1.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OEU10028.1 - 0.00063 19.9 1.2 0.00082 19.6 1.2 1.3 1 0 0 1 1 1 1 Acyl-carrier PRD PF00874.20 OEU10028.1 - 0.081 13.2 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 PRD domain VPS13_C PF16909.5 OEU10029.1 - 0.0065 16.3 15.3 0.041 13.7 0.0 3.8 2 1 2 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal HTH_19 PF12844.7 OEU10029.1 - 0.12 12.5 0.1 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Chorein_N PF12624.7 OEU10030.1 - 9.4e-18 64.4 0.1 2.4e-17 63.1 0.1 1.6 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 PPDFL PF15060.6 OEU10033.1 - 0.17 12.4 0.2 0.17 12.4 0.2 3.2 3 1 1 4 4 4 0 Differentiation and proliferation regulator Exo_endo_phos PF03372.23 OEU10035.1 - 7.3e-05 22.4 0.0 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GARS_A PF01071.19 OEU10035.1 - 0.031 14.1 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Cofac_haem_bdg PF04187.13 OEU10035.1 - 0.87 9.5 6.5 1.2 9.1 0.7 2.8 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN zf-RVT PF13966.6 OEU10036.1 - 0.00036 21.2 3.9 0.0015 19.2 3.9 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Jak1_Phl PF17887.1 OEU10036.1 - 2.2 8.2 6.2 1.2 9.1 2.3 2.7 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain UPF0300 PF08594.10 OEU10037.1 - 0.17 11.1 0.7 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0300) N2227 PF07942.12 OEU10038.1 - 5.7e-81 271.7 0.0 1.4e-80 270.4 0.0 1.5 2 0 0 2 2 2 1 N2227-like protein Methyltransf_11 PF08241.12 OEU10038.1 - 2.2e-05 25.0 0.0 0.038 14.6 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OEU10038.1 - 8e-05 23.3 0.0 0.00069 20.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU10038.1 - 0.00016 21.5 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU10038.1 - 0.011 16.4 0.0 3.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_C1 PF00112.23 OEU10039.1 - 1.5e-42 146.1 5.3 2.3e-42 145.5 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OEU10039.1 - 0.017 14.0 2.9 0.05 12.4 1.4 2.0 2 0 0 2 2 2 0 Peptidase C1-like family His_Phos_1 PF00300.22 OEU10040.1 - 1.1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OEU10040.1 - 0.053 12.9 0.1 0.31 10.3 0.0 1.9 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) UCH PF00443.29 OEU10041.1 - 2.3e-37 128.9 0.0 2.3e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU10041.1 - 1.5e-11 44.5 0.6 4.9e-09 36.2 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 OEU10041.1 - 5.5e-10 38.9 0.2 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 OEU10041.1 - 5.2e-07 29.9 0.0 1.8e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein PHD_2 PF13831.6 OEU10041.1 - 0.13 11.8 1.8 3.5 7.3 0.2 2.5 2 0 0 2 2 2 0 PHD-finger SET PF00856.28 OEU10042.1 - 3.3e-13 50.4 0.0 7.1e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 SET domain SBF2 PF12335.8 OEU10044.1 - 1.3e-06 28.2 0.5 1.3e-06 28.2 0.5 2.8 4 0 0 4 4 4 1 Myotubularin protein DUF2969 PF11184.8 OEU10044.1 - 0.0011 19.3 0.0 0.0035 17.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2969) ABC1 PF03109.16 OEU10044.1 - 0.29 11.3 1.9 12 6.0 0.0 3.4 3 0 0 3 3 3 0 ABC1 family Inositol_P PF00459.25 OEU10045.1 - 1.8e-21 76.9 0.1 3.1e-21 76.1 0.1 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family FBPase_glpX PF03320.13 OEU10045.1 - 0.043 12.7 0.0 1.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded UPF0047 PF01894.17 OEU10046.1 - 2e-31 108.5 0.0 2.7e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Peptidase_C1 PF00112.23 OEU10047.1 - 2.1e-34 119.5 8.0 5e-33 115.0 8.0 2.1 1 1 0 1 1 1 1 Papain family cysteine protease Flu_M2 PF00599.17 OEU10047.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Secretin_N_2 PF07655.13 OEU10047.1 - 0.22 12.1 7.9 0.45 11.1 7.9 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Peptidase_C1 PF00112.23 OEU10048.1 - 8e-41 140.5 5.0 1.2e-40 140.0 5.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OEU10048.1 - 0.00081 18.3 3.1 0.0025 16.7 1.3 2.3 2 1 1 3 3 3 1 Peptidase C1-like family DUF3439 PF11921.8 OEU10049.1 - 0.01 15.8 9.1 0.01 15.8 9.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 OEU10049.1 - 0.096 12.7 21.3 0.19 11.7 21.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 OEU10049.1 - 0.16 10.0 3.7 0.2 9.6 3.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NGP1NT PF08153.12 OEU10051.1 - 4.6e-38 130.3 0.0 7.7e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OEU10051.1 - 7.4e-18 64.7 0.2 1.1e-14 54.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU10051.1 - 1.4e-06 27.9 0.0 4.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OEU10051.1 - 3.3e-06 27.1 0.0 8.4e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OEU10051.1 - 0.0051 16.9 0.5 0.27 11.3 0.1 2.6 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 OEU10051.1 - 0.015 14.8 0.1 3.7 7.0 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain cobW PF02492.19 OEU10051.1 - 0.027 14.0 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 OEU10051.1 - 0.037 13.5 0.1 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 OEU10051.1 - 0.053 13.7 0.1 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TCR PF03638.15 OEU10052.1 - 1.2e-20 73.5 51.0 1.3e-10 41.4 18.1 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain preSET_CXC PF18264.1 OEU10052.1 - 0.028 14.9 17.7 0.028 14.9 17.7 2.8 2 1 0 2 2 2 0 CXC domain MSL2-CXC PF16682.5 OEU10052.1 - 9.8 6.4 43.3 1.1 9.4 13.0 2.7 2 2 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 PDZ PF00595.24 OEU10053.1 - 1.8e-24 85.9 1.4 2.6e-05 24.5 0.2 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 OEU10053.1 - 1.3e-17 63.4 0.1 0.0001 22.1 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 OEU10053.1 - 1.1e-16 60.9 2.5 3.2e-05 24.1 0.0 4.9 4 0 0 4 4 4 4 PDZ domain Tricorn_PDZ PF14685.6 OEU10053.1 - 1e-06 28.6 0.2 5.1 7.1 0.0 4.6 4 0 0 4 4 4 3 Tricorn protease PDZ domain TF_Zn_Ribbon PF08271.12 OEU10054.1 - 1.8e-10 40.2 22.9 2.8e-06 26.7 4.9 3.8 3 0 0 3 3 3 2 TFIIB zinc-binding DZR PF12773.7 OEU10054.1 - 4.5e-06 26.6 7.7 0.0038 17.2 1.0 2.6 1 1 1 2 2 2 2 Double zinc ribbon A2L_zn_ribbon PF08792.10 OEU10054.1 - 1e-05 25.1 23.2 0.0017 18.0 3.7 4.0 3 1 0 3 3 3 2 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.11 OEU10054.1 - 0.00046 20.1 9.6 0.1 12.5 1.1 3.1 3 0 0 3 3 3 2 Putative transposase DNA-binding domain zinc_ribbon_10 PF10058.9 OEU10054.1 - 0.0057 16.3 12.7 0.84 9.4 0.0 3.7 2 1 0 3 3 3 2 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 OEU10054.1 - 0.0084 16.1 9.8 0.67 10.0 0.8 3.0 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1451 PF07295.11 OEU10054.1 - 0.01 15.9 10.2 0.41 10.7 0.5 3.0 3 0 0 3 3 3 0 Zinc-ribbon containing domain DNA_RNApol_7kD PF03604.13 OEU10054.1 - 0.03 14.0 16.9 0.75 9.5 2.9 3.7 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit RNA_POL_M_15KD PF02150.16 OEU10054.1 - 0.032 14.1 10.1 7.1 6.6 0.2 3.8 4 0 0 4 4 3 0 RNA polymerases M/15 Kd subunit BUD22 PF09073.10 OEU10054.1 - 0.038 13.3 3.6 0.035 13.5 3.6 1.3 1 0 0 1 1 1 0 BUD22 PDZ_6 PF17820.1 OEU10054.1 - 0.042 13.7 0.3 0.088 12.7 0.3 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 OEU10054.1 - 0.043 14.2 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Zn-ribbon_8 PF09723.10 OEU10054.1 - 0.05 13.7 16.1 0.098 12.8 1.4 3.4 1 1 3 4 4 4 0 Zinc ribbon domain DUF4503 PF14951.6 OEU10054.1 - 0.054 12.0 8.9 0.24 9.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4503) zf-ribbon_3 PF13248.6 OEU10054.1 - 0.085 12.3 20.8 0.4 10.1 0.1 5.1 4 1 0 4 4 4 0 zinc-ribbon domain GCIP PF13324.6 OEU10054.1 - 0.12 12.0 6.6 0.22 11.1 6.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting zf_UBZ PF18439.1 OEU10054.1 - 0.12 12.0 0.2 0.12 12.0 0.2 4.2 5 0 0 5 5 4 0 Ubiquitin-Binding Zinc Finger SDH_sah PF01972.16 OEU10054.1 - 0.14 11.2 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase RNHCP PF12647.7 OEU10054.1 - 0.15 12.0 17.8 3.8 7.5 0.3 3.8 1 1 0 2 2 2 0 RNHCP domain DUF2318 PF10080.9 OEU10054.1 - 0.38 10.9 11.7 0.92 9.7 0.9 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) Trm112p PF03966.16 OEU10054.1 - 0.48 11.0 5.2 7.2 7.3 0.5 2.7 1 1 1 2 2 2 0 Trm112p-like protein Rubredoxin_2 PF18073.1 OEU10054.1 - 0.65 9.8 16.0 11 5.9 0.1 4.9 5 0 0 5 5 5 0 Rubredoxin metal binding domain TFIIS_C PF01096.18 OEU10054.1 - 0.72 9.8 17.0 6 6.8 0.1 5.0 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) Cwf_Cwc_15 PF04889.12 OEU10054.1 - 0.81 9.4 12.5 0.026 14.2 6.6 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TackOD1 PF18551.1 OEU10054.1 - 1.1 9.0 12.0 3.2 7.4 12.0 1.7 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 Nop14 PF04147.12 OEU10054.1 - 2.3 6.3 8.6 2.6 6.2 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2HC5 PF06221.13 OEU10054.1 - 3.1 7.9 11.9 1.2 9.2 0.6 3.4 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type FUR PF01475.19 OEU10054.1 - 5.8 7.1 6.3 20 5.4 1.7 2.3 1 1 1 2 2 2 0 Ferric uptake regulator family CDC45 PF02724.14 OEU10054.1 - 6.3 5.0 7.5 8.2 4.6 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OEU10054.1 - 7.3 6.2 7.1 1.3 8.6 3.2 1.8 2 0 0 2 2 2 0 FAM176 family Nudix_N_2 PF14803.6 OEU10054.1 - 7.6 6.6 23.3 0.43 10.5 1.4 4.6 3 2 2 5 5 5 0 Nudix N-terminal RRN3 PF05327.11 OEU10054.1 - 8.2 4.8 5.9 12 4.3 5.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C3HC PF07967.13 OEU10055.1 - 6e-05 23.1 0.0 9.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 C3HC zinc finger-like CNOT11 PF10155.9 OEU10056.1 - 1.6e-46 157.5 2.2 2.1e-46 157.1 2.2 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Adeno_PV PF03910.13 OEU10056.1 - 0.053 12.2 0.0 0.065 11.9 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV PEX11 PF05648.14 OEU10057.1 - 1.4e-07 31.2 1.8 0.0001 21.9 0.2 2.3 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF3915 PF13054.6 OEU10058.1 - 0.96 9.4 12.2 2.1 8.3 12.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Sel1 PF08238.12 OEU10059.1 - 1.5e-08 35.0 5.7 0.00092 19.8 0.0 4.8 5 0 0 5 5 5 3 Sel1 repeat AIRC PF00731.20 OEU10060.1 - 1.1e-64 216.5 0.6 1.1e-64 216.5 0.6 2.5 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.22 OEU10060.1 - 6.5e-47 159.3 0.0 1.3e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 OEU10060.1 - 3.3e-19 68.3 0.1 7e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 OEU10060.1 - 8.6e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.11 OEU10060.1 - 0.057 13.0 0.2 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Dala_Dala_lig_C PF07478.13 OEU10060.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Complex1_LYR PF05347.15 OEU10062.1 - 2.8e-09 36.9 0.2 4.2e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 OEU10062.1 - 0.0049 17.4 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 OEU10062.1 - 0.0064 17.2 0.4 0.0086 16.8 0.4 1.5 1 1 0 1 1 1 1 Complex1_LYR-like COG6 PF06419.11 OEU10063.1 - 2.7e-13 49.0 0.0 3.1e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 NUDIX PF00293.28 OEU10064.1 - 1.5e-09 37.9 0.0 2.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N PF00107.26 OEU10065.1 - 5.4e-22 78.2 0.0 1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU10065.1 - 1.6e-14 55.1 0.0 4.7e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU10065.1 - 0.00011 22.0 0.2 0.00024 21.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.21 OEU10065.1 - 0.058 13.5 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Proteasome_A_N PF10584.9 OEU10065.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature ADH_N_2 PF16884.5 OEU10065.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short PF00106.25 OEU10065.1 - 0.84 9.1 4.7 0.13 11.7 0.3 1.9 3 0 0 3 3 3 0 short chain dehydrogenase Pyridoxal_deC PF00282.19 OEU10066.1 - 1.7e-28 99.4 0.0 1.6e-27 96.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OEU10066.1 - 1.2e-07 31.0 0.0 4.1e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OEU10066.1 - 2.9e-07 30.0 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OEU10066.1 - 0.00017 20.9 0.0 0.00068 18.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 OEU10066.1 - 0.031 13.3 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase RRM_1 PF00076.22 OEU10067.1 - 6.4e-24 83.6 0.0 1.6e-12 47.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU10067.1 - 0.00013 22.0 0.0 0.25 11.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 OEU10067.1 - 0.0048 16.7 0.0 4.1 7.3 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif Myb_DNA-binding PF00249.31 OEU10070.1 - 1.7e-37 127.4 8.5 6.7e-16 58.2 0.1 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU10070.1 - 6.7e-32 109.5 3.1 1.1e-17 64.0 0.1 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OEU10070.1 - 0.0016 18.6 0.1 0.45 10.7 0.0 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OEU10070.1 - 0.0045 17.1 0.7 0.029 14.5 0.7 2.0 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OEU10070.1 - 0.0062 16.5 0.0 3.7 7.6 0.0 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OEU10070.1 - 0.018 14.9 0.0 4.4 7.3 0.0 2.3 1 1 1 2 2 2 0 Myb DNA-binding like DUF3012 PF11216.8 OEU10070.1 - 0.082 13.0 0.5 6.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) RNA_pol_I_A49 PF06870.12 OEU10071.1 - 4.2e-39 134.5 0.0 5.9e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor TauE PF01925.19 OEU10072.1 - 4.3e-33 114.9 11.0 4e-21 75.7 3.2 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Lactamase_B PF00753.27 OEU10073.1 - 1.7e-11 44.5 0.1 7.9e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OEU10073.1 - 1.3e-06 28.0 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain cNMP_binding PF00027.29 OEU10073.1 - 0.036 14.1 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain HD_4 PF13328.6 OEU10076.1 - 5.5e-47 159.4 0.0 1e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 OEU10076.1 - 7.2e-27 94.0 0.0 1.7e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 OEU10076.1 - 2.7e-15 56.1 0.0 8.8e-15 54.5 0.0 1.9 2 0 0 2 2 2 1 TGS domain HD PF01966.22 OEU10076.1 - 9.9e-08 32.2 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 HD domain Ub-Mut7C PF14451.6 OEU10076.1 - 0.0055 16.5 0.1 0.02 14.8 0.1 1.9 1 0 0 1 1 1 1 Mut7-C ubiquitin ThiS PF02597.20 OEU10076.1 - 0.097 13.3 0.1 0.94 10.2 0.1 2.4 1 1 0 1 1 1 0 ThiS family CMS1 PF14617.6 OEU10077.1 - 0.063 12.6 0.9 0.12 11.7 0.9 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 OEU10078.1 - 5.6e-43 146.5 0.2 2.4e-42 144.5 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU10078.1 - 7.6e-12 44.8 0.1 2.6e-11 43.1 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_2 PF07724.14 OEU10078.1 - 2.9e-06 27.5 0.1 7.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 OEU10078.1 - 6.6e-06 26.0 0.2 1.8e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 OEU10078.1 - 1.1e-05 25.9 0.0 0.00011 22.6 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OEU10078.1 - 1.1e-05 25.5 0.0 4.9e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU10078.1 - 8.4e-05 22.4 0.0 0.00021 21.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU10078.1 - 0.00011 22.5 0.4 0.0066 16.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU10078.1 - 0.0021 18.2 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OEU10078.1 - 0.0023 17.4 0.2 0.18 11.3 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.17 OEU10078.1 - 0.0035 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OEU10078.1 - 0.0049 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 OEU10078.1 - 0.0064 16.2 0.0 0.058 13.1 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OEU10078.1 - 0.0069 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OEU10078.1 - 0.0076 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU10078.1 - 0.0077 16.8 0.0 0.033 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OEU10078.1 - 0.011 15.1 0.1 0.025 13.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OEU10078.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OEU10078.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_13 PF13166.6 OEU10078.1 - 0.031 12.9 0.1 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OEU10078.1 - 0.036 13.8 0.0 0.099 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OEU10078.1 - 0.04 14.3 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 OEU10078.1 - 0.045 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 OEU10078.1 - 0.046 14.0 0.4 0.097 12.9 0.4 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF815 PF05673.13 OEU10078.1 - 0.048 12.8 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DivIC PF04977.15 OEU10078.1 - 0.055 13.3 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Zeta_toxin PF06414.12 OEU10078.1 - 0.06 12.6 0.1 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OEU10078.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OEU10078.1 - 0.063 13.8 0.1 0.42 11.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 OEU10078.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OEU10078.1 - 0.079 12.3 0.0 0.23 10.8 0.0 1.8 1 0 0 1 1 1 0 KaiC Seryl_tRNA_N PF02403.22 OEU10078.1 - 0.081 13.2 0.9 0.23 11.7 0.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_19 PF13245.6 OEU10078.1 - 0.095 13.0 0.1 0.66 10.3 0.1 2.3 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 OEU10078.1 - 0.095 12.5 0.2 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OEU10078.1 - 0.1 13.0 0.1 0.75 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1090 PF06476.12 OEU10078.1 - 0.11 12.7 2.1 1 9.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF3510 PF12022.8 OEU10078.1 - 0.13 12.6 0.3 0.28 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) UbiA PF01040.18 OEU10079.1 - 1e-18 67.5 19.7 7.4e-18 64.8 19.7 2.1 1 1 0 1 1 1 1 UbiA prenyltransferase family TTD PF12148.8 OEU10080.1 - 6e-05 23.0 1.4 0.00017 21.5 0.1 2.2 2 1 0 2 2 2 1 Tandem tudor domain within UHRF1 Imm42 PF15593.6 OEU10081.1 - 0.068 13.7 0.7 0.068 13.7 0.7 2.1 2 1 1 3 3 3 0 Immunity protein 42 CYYR1 PF10873.8 OEU10081.1 - 1.9 8.9 3.9 3.2 8.2 3.9 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Glyoxalase_4 PF13669.6 OEU10082.1 - 4.2e-19 68.8 0.0 5.9e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tic22 PF04278.12 OEU10083.1 - 1.1e-10 41.4 0.0 1.3e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Tic22-like family Cmc1 PF08583.10 OEU10085.1 - 0.00072 19.5 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 OEU10085.1 - 0.072 12.8 0.5 0.52 10.1 0.3 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PA26 PF04636.13 OEU10087.1 - 5.4 5.8 19.2 1.5 7.6 5.2 2.0 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) MRP-S28 PF10213.9 OEU10088.1 - 9.9e-13 48.6 0.1 1.4e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein RF-1 PF00472.20 OEU10088.1 - 0.044 13.7 1.3 0.078 12.9 1.3 1.4 1 0 0 1 1 1 0 RF-1 domain DUF3486 PF11985.8 OEU10088.1 - 0.055 13.9 0.1 0.071 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) IF-2B PF01008.17 OEU10090.1 - 2.5e-54 184.4 0.0 7.3e-53 179.6 0.0 2.0 2 0 0 2 2 2 2 Initiation factor 2 subunit family Methyltrn_RNA_3 PF02598.17 OEU10091.1 - 1.1e-104 350.0 0.0 1.3e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase NOA36 PF06524.12 OEU10091.1 - 4.8 6.4 9.7 7 5.9 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein CN_hydrolase PF00795.22 OEU10092.1 - 1.3e-50 172.2 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Beta_propel PF09826.9 OEU10092.1 - 0.012 14.5 0.1 0.024 13.5 0.0 1.4 2 0 0 2 2 2 0 Beta propeller domain Ras PF00071.22 OEU10094.1 - 3.4e-43 147.1 0.1 4.8e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU10094.1 - 8.4e-27 93.8 0.0 2.2e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU10094.1 - 8.3e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OEU10094.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NDUFA12 PF05071.16 OEU10095.1 - 4.7e-14 53.0 0.7 8.6e-14 52.2 0.7 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Aquarius_N PF16399.5 OEU10096.1 - 3e-116 389.4 0.1 4.6e-116 388.8 0.1 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 OEU10096.1 - 1.6e-26 93.1 0.0 5.3e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OEU10096.1 - 4.4e-16 59.4 0.0 2.8e-11 43.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OEU10096.1 - 3.3e-07 30.7 0.0 3.3e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OEU10096.1 - 3.1e-06 27.1 0.0 0.00056 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OEU10096.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OEU10096.1 - 0.0025 17.9 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OEU10096.1 - 0.0027 17.3 0.0 0.0089 15.6 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 OEU10096.1 - 0.0037 16.6 0.4 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OEU10096.1 - 0.0096 16.3 0.1 0.092 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OEU10096.1 - 0.015 15.8 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU10096.1 - 0.037 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OEU10096.1 - 0.042 13.3 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.6 OEU10096.1 - 0.055 13.3 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OEU10096.1 - 0.058 13.7 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OEU10096.1 - 0.06 13.8 0.1 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OEU10096.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.16 OEU10097.1 - 7e-24 84.4 29.0 1.5e-16 60.3 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU10097.1 - 3.6e-05 22.8 28.1 0.0031 16.4 10.3 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OEU10097.1 - 0.00014 20.9 10.0 0.0014 17.6 9.7 2.5 1 1 0 1 1 1 1 MFS_1 like family ADH_zinc_N PF00107.26 OEU10098.1 - 3.1e-23 82.2 0.3 5.2e-23 81.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU10098.1 - 4.2e-18 65.2 4.7 9.1e-18 64.1 4.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OEU10098.1 - 0.0029 16.9 0.5 0.0051 16.1 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OEU10098.1 - 0.0035 16.7 0.1 0.0059 16.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OEU10098.1 - 0.033 13.7 0.2 0.057 13.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CoA_binding PF02629.19 OEU10098.1 - 0.042 14.5 0.2 0.12 13.1 0.2 1.8 1 1 0 1 1 1 0 CoA binding domain TrkA_N PF02254.18 OEU10098.1 - 0.048 13.9 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HSP70 PF00012.20 OEU10099.1 - 6e-76 255.9 0.1 8.2e-76 255.5 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OEU10099.1 - 1.5e-15 56.9 0.6 3.2e-11 42.6 0.1 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 OEU10099.1 - 1.3e-05 25.0 0.0 5.9e-05 22.9 0.0 2.1 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 OEU10099.1 - 2.3e-05 23.8 0.9 0.00013 21.3 0.0 2.1 2 0 0 2 2 2 1 StbA protein FtsA PF14450.6 OEU10099.1 - 0.0027 18.1 0.1 2.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Cell division protein FtsA DUF2729 PF10870.8 OEU10099.1 - 0.36 10.7 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Peptidase_C69 PF03577.15 OEU10101.1 - 4.9e-72 243.1 2.2 1.3e-70 238.3 2.2 2.1 1 1 0 1 1 1 1 Peptidase family C69 zf-CCHC_5 PF14787.6 OEU10102.1 - 0.09 12.5 0.7 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C2HC_2 PF13913.6 OEU10102.1 - 5.4 7.0 16.5 1.1 9.2 0.3 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Chloroa_b-bind PF00504.21 OEU10103.1 - 1.3e-30 107.1 0.2 1.9e-30 106.5 0.1 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein DUF4148 PF13663.6 OEU10103.1 - 0.52 10.5 2.7 0.36 11.0 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) SHIPPO-rpt PF07004.12 OEU10105.1 - 0.0042 17.9 10.7 1.2 10.2 0.7 3.8 2 1 1 3 3 3 3 Sperm-tail PG-rich repeat Cnd2 PF05786.14 OEU10106.1 - 0.0019 17.0 1.3 0.0022 16.8 1.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 PDZ_6 PF17820.1 OEU10106.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 PDZ domain DNA_pol_phi PF04931.13 OEU10106.1 - 3.8 5.5 8.1 4.6 5.2 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2061 PF09834.9 OEU10107.1 - 4.1e-23 81.6 10.3 2.3e-13 50.4 2.7 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2061) LST1 PF05083.13 OEU10108.1 - 0.18 12.1 0.0 0.54 10.6 0.0 1.8 1 0 0 1 1 1 0 LST-1 protein INSIG PF07281.12 OEU10109.1 - 0.0003 20.5 0.1 0.17 11.5 0.0 2.5 2 1 0 2 2 2 2 Insulin-induced protein (INSIG) DUF4971 PF16341.5 OEU10109.1 - 0.062 13.1 0.8 0.13 12.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) AAA_lid_9 PF17871.1 OEU10109.1 - 0.17 11.8 1.5 17 5.4 0.2 2.6 2 1 1 3 3 3 0 AAA lid domain DUF1451 PF07295.11 OEU10110.1 - 0.011 15.8 0.3 0.058 13.4 0.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain p450 PF00067.22 OEU10111.1 - 2.7e-76 257.2 0.0 4.6e-76 256.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MAGUK_N_PEST PF10608.9 OEU10111.1 - 0.12 12.8 0.0 0.93 9.9 0.0 2.3 2 1 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Patatin PF01734.22 OEU10113.1 - 7e-08 32.9 0.0 2.9e-06 27.6 0.0 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Acetyltransf_1 PF00583.25 OEU10115.1 - 1.2e-06 28.8 0.0 2.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU10115.1 - 4.7e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU10115.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_ribbon_2 PF12674.7 OEU10115.1 - 0.34 11.6 5.1 33 5.2 0.2 3.7 3 0 0 3 3 3 0 Putative zinc ribbon domain AfsA PF03756.13 OEU10116.1 - 0.023 14.7 0.0 0.028 14.4 0.0 1.0 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain RNA_pol_Rpb6 PF01192.22 OEU10117.1 - 4.3e-16 58.6 0.2 5.3e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 YodL PF14191.6 OEU10118.1 - 0.016 16.0 2.7 0.078 13.8 0.2 2.7 2 0 0 2 2 2 0 YodL-like DUF4724 PF15852.5 OEU10118.1 - 2.7 8.5 6.6 0.93 10.0 1.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) Ecm29 PF13001.7 OEU10119.1 - 1.5e-09 37.1 9.7 5.8e-09 35.2 2.6 4.1 3 1 0 3 3 3 1 Proteasome stabiliser TAN PF11640.8 OEU10119.1 - 0.026 14.6 0.7 1.1 9.4 0.0 3.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair HEAT PF02985.22 OEU10119.1 - 4.3 7.9 26.6 18 5.9 0.1 8.7 9 0 0 9 9 9 0 HEAT repeat CTP_synth_N PF06418.14 OEU10120.1 - 2.1e-114 381.3 0.0 2.8e-114 380.9 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OEU10120.1 - 7.3e-55 185.7 0.0 1.3e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OEU10120.1 - 3e-05 23.9 0.0 0.00083 19.2 0.0 2.6 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 OEU10120.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 OEU10120.1 - 0.017 14.1 0.5 0.031 13.3 0.5 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 5TM-5TMR_LYT PF07694.12 OEU10120.1 - 0.12 11.8 1.2 0.21 11.1 1.2 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT zf-RING_2 PF13639.6 OEU10122.1 - 1.8e-06 28.2 8.8 5.1e-06 26.7 8.8 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OEU10122.1 - 3.3e-05 23.7 5.6 9.4e-05 22.2 5.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU10122.1 - 0.00015 21.4 4.7 0.00036 20.2 4.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OEU10122.1 - 0.00023 21.1 1.7 0.00023 21.1 1.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OEU10122.1 - 0.00026 21.1 7.3 0.0005 20.2 7.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 OEU10122.1 - 0.0021 18.3 6.6 0.0075 16.5 6.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Tmpp129 PF10272.9 OEU10122.1 - 0.0045 16.4 1.8 0.0045 16.4 1.8 1.5 2 0 0 2 2 2 1 Putative transmembrane protein precursor Prok-RING_1 PF14446.6 OEU10122.1 - 0.025 14.5 5.0 0.042 13.8 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 OEU10122.1 - 0.031 13.9 2.4 0.071 12.8 2.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU10122.1 - 0.092 12.6 8.3 0.34 10.8 8.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU10122.1 - 0.097 12.7 5.7 0.91 9.6 5.7 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OEU10122.1 - 0.12 12.2 9.8 2.4 8.1 9.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU10122.1 - 0.57 10.2 10.7 0.05 13.6 5.4 2.1 2 1 0 2 2 1 0 zinc-RING finger domain FKBP_C PF00254.28 OEU10123.1 - 7.7e-13 48.6 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4131 PF13567.6 OEU10123.1 - 0.014 15.1 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 OEU10124.1 - 1.1e-11 44.4 0.0 2.9e-06 27.0 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OEU10124.1 - 0.0054 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OEU10124.1 - 0.021 14.8 0.1 0.21 11.6 0.0 2.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif MYT1 PF08474.11 OEU10124.1 - 0.026 14.5 0.3 0.044 13.7 0.3 1.4 1 0 0 1 1 1 0 Myelin transcription factor 1 DUF4523 PF15023.6 OEU10124.1 - 0.12 12.2 1.6 0.42 10.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Internalin_N PF12354.8 OEU10125.1 - 0.027 14.6 0.1 0.065 13.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Fer2 PF00111.27 OEU10127.1 - 1.3e-10 41.1 0.5 1.5e-10 40.8 0.5 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TF_Zn_Ribbon PF08271.12 OEU10127.1 - 0.089 12.3 1.0 0.15 11.6 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Myb_DNA-binding PF00249.31 OEU10128.1 - 0.0042 17.2 0.1 0.0093 16.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU10128.1 - 0.064 13.5 0.5 0.25 11.6 0.2 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Forkhead_N PF08430.12 OEU10129.1 - 1.8 9.2 53.5 1.6 9.4 38.2 2.3 1 1 1 2 2 2 0 Forkhead N-terminal region HSF_DNA-bind PF00447.17 OEU10130.1 - 4.4e-16 59.3 0.6 5.7e-16 58.9 0.6 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Fasciclin PF02469.22 OEU10131.1 - 8.1e-25 87.5 0.0 9.3e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 OEU10132.1 - 1.7e-23 83.2 0.0 1.9e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain DUF4993 PF16384.5 OEU10132.1 - 0.008 15.2 0.0 0.009 15.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function Fasciclin PF02469.22 OEU10133.1 - 1.1e-29 103.2 0.5 1.3e-29 103.0 0.5 1.0 1 0 0 1 1 1 1 Fasciclin domain His_Phos_1 PF00300.22 OEU10134.1 - 3e-19 69.5 0.2 3e-15 56.4 0.2 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) UPF0560 PF10577.9 OEU10134.1 - 0.077 11.5 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DinB_2 PF12867.7 OEU10134.1 - 0.1 13.1 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily DUF1736 PF08409.11 OEU10135.1 - 3.1e-18 65.5 0.4 9.3e-18 64.0 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) GntP_permease PF02447.16 OEU10135.1 - 0.075 11.7 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 GntP family permease Glyco_transf_90 PF05686.12 OEU10136.1 - 2.4e-15 56.4 5.2 5.7e-13 48.5 5.2 2.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 Aldo_ket_red PF00248.21 OEU10137.1 - 2.7e-60 204.1 0.0 3.4e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MSP1a PF11670.8 OEU10138.1 - 0.065 12.5 0.1 0.098 11.9 0.1 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) SURF2 PF05477.11 OEU10138.1 - 3.2 7.4 5.3 4.4 6.9 5.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Abhydrolase_1 PF00561.20 OEU10139.1 - 1.6e-12 47.6 0.2 2.8e-09 37.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU10139.1 - 8.7e-12 46.1 0.0 3.5e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU10139.1 - 1.5e-11 44.1 0.0 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OEU10139.1 - 0.00021 21.2 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 OEU10139.1 - 0.13 11.9 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Ank_2 PF12796.7 OEU10140.1 - 2.1e-22 79.5 1.9 3.3e-08 34.0 0.1 5.7 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU10140.1 - 2.5e-18 66.2 1.3 0.00034 21.1 0.1 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OEU10140.1 - 1.9e-17 62.8 0.0 1.7e-05 25.0 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OEU10140.1 - 6.7e-13 47.6 0.2 0.18 12.4 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OEU10140.1 - 3.9e-05 23.8 14.1 0.17 12.3 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) TniB PF05621.11 OEU10140.1 - 0.0053 16.2 0.4 3.3 7.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial TniB protein HP0268 PF18618.1 OEU10140.1 - 0.18 12.2 3.5 1.6 9.2 0.8 2.9 2 0 0 2 2 2 0 HP0268 RIO1 PF01163.22 OEU10143.1 - 2.5e-52 177.2 0.0 3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OEU10143.1 - 0.0002 21.4 0.0 0.0041 17.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU10143.1 - 0.003 17.0 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU10143.1 - 0.0037 16.1 0.0 0.011 14.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase UCR_Fe-S_N PF10399.9 OEU10144.1 - 7.8e-07 28.3 0.1 1.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4587 PF15248.6 OEU10144.1 - 0.11 13.3 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) PUB PF09409.10 OEU10146.1 - 1.2e-08 34.8 0.3 4.7e-08 32.8 0.3 2.0 1 0 0 1 1 1 1 PUB domain Ank_2 PF12796.7 OEU10147.1 - 7.2e-07 29.7 0.0 0.33 11.6 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU10147.1 - 0.00046 20.4 4.6 11 6.9 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OEU10147.1 - 0.00092 19.5 0.5 0.25 11.7 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU10147.1 - 0.016 15.7 0.5 35 5.1 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat PseudoU_synth_2 PF00849.22 OEU10148.1 - 3.7e-26 92.1 0.0 5.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3727 PF12527.8 OEU10149.1 - 0.61 10.4 9.6 2.3 8.5 0.3 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF3727) Mod_r PF07200.13 OEU10152.1 - 9.7e-29 100.3 2.3 1.3e-28 100.0 2.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein JAKMIP_CC3 PF16034.5 OEU10152.1 - 0.021 14.8 1.4 0.021 14.8 1.4 1.7 2 0 0 2 2 2 0 JAKMIP CC3 domain WD40 PF00400.32 OEU10153.1 - 1.4e-15 57.3 8.8 3.8e-05 24.4 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat LisH_TPL PF17814.1 OEU10153.1 - 3e-05 23.6 0.0 5.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 OEU10153.1 - 0.00021 21.5 0.2 0.0044 17.3 0.1 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OEU10153.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 OEU10153.1 - 0.018 13.8 0.5 0.21 10.3 0.1 2.7 3 1 0 3 3 3 0 Nup133 N terminal like Tudor_2 PF18104.1 OEU10155.1 - 1.8e-06 27.5 4.7 0.094 12.4 0.2 3.7 3 0 0 3 3 3 2 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 OEU10155.1 - 0.00024 20.8 0.6 0.52 10.1 0.0 3.3 3 0 0 3 3 3 2 Histone methyltransferase Tudor domain 1 SR-25 PF10500.9 OEU10155.1 - 0.0084 15.7 1.7 0.0084 15.7 1.7 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Spin-Ssty PF02513.17 OEU10155.1 - 0.0087 15.8 1.1 0.36 10.6 0.2 2.7 2 0 0 2 2 2 1 Spin/Ssty Family SM-ATX PF14438.6 OEU10155.1 - 0.017 15.2 0.5 10 6.4 0.0 3.0 3 0 0 3 3 3 0 Ataxin 2 SM domain DUF4537 PF15057.6 OEU10155.1 - 0.031 14.3 0.3 9.8 6.2 0.1 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4537) LSM14 PF12701.7 OEU10155.1 - 0.039 14.1 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Scd6-like Sm domain PTPRCAP PF15713.5 OEU10155.1 - 0.32 11.3 6.9 1.5 9.1 1.4 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.6 OEU10155.1 - 0.57 10.6 4.9 4.7 7.6 1.2 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Secretin_N_2 PF07655.13 OEU10155.1 - 0.78 10.3 10.5 2.1 8.9 3.7 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain CSD PF00313.22 OEU10155.1 - 0.81 9.6 5.3 3.6 7.5 0.1 3.7 3 1 1 4 4 4 0 'Cold-shock' DNA-binding domain Sporozoite_P67 PF05642.11 OEU10155.1 - 1 7.4 10.8 1.4 6.9 6.3 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen P_C10 PF14974.6 OEU10156.1 - 0.0085 16.2 2.0 0.031 14.4 0.1 2.4 2 1 0 2 2 2 1 Protein C10 CUE PF02845.16 OEU10157.1 - 4.5e-06 26.2 0.1 1.5e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 CUE domain MS_channel PF00924.18 OEU10158.1 - 2.6e-12 46.7 1.5 5.6e-12 45.7 1.5 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 OEU10158.1 - 0.4 11.2 3.3 0.7 10.4 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain pair LRR_6 PF13516.6 OEU10159.1 - 5.7e-16 57.2 12.3 0.017 15.1 0.2 6.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 OEU10159.1 - 2.4e-06 27.8 9.5 1.3 9.5 1.1 4.7 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU10159.1 - 0.00034 20.8 8.4 1.2 10.0 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 OEU10159.1 - 0.23 11.3 11.8 1.9 8.3 2.4 4.8 3 1 1 4 4 4 0 Leucine rich repeat Response_reg PF00072.24 OEU10160.1 - 4.3e-20 72.0 0.1 1.3e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HSP70 PF00012.20 OEU10161.1 - 2.8e-259 861.4 4.5 3.5e-259 861.1 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OEU10161.1 - 1.7e-15 56.7 0.1 1.6e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 OEU10161.1 - 0.013 14.5 0.1 0.058 12.4 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FCSD-flav_bind PF09242.11 OEU10161.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding PilM_2 PF11104.8 OEU10161.1 - 0.043 12.9 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.18 OEU10161.1 - 0.068 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase p450 PF00067.22 OEU10162.1 - 9.2e-28 97.2 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Tim17 PF02466.19 OEU10163.1 - 7.8e-29 100.3 5.5 9.4e-29 100.0 5.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Thioredoxin PF00085.20 OEU10164.1 - 4.1e-15 55.6 0.0 9.3e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU10164.1 - 0.0007 20.0 0.0 0.0016 18.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU10164.1 - 0.0041 17.4 0.1 0.039 14.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OEU10164.1 - 0.081 12.6 0.1 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 Redoxin AhpC-TSA PF00578.21 OEU10164.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family AIG2_2 PF13772.6 OEU10165.1 - 9.5e-06 25.9 0.1 0.0033 17.8 0.1 2.5 1 1 0 1 1 1 1 AIG2-like family GGACT PF06094.12 OEU10165.1 - 0.00085 19.9 0.0 0.0036 17.9 0.0 1.7 1 1 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like Dicty_REP PF05086.12 OEU10165.1 - 0.0024 15.9 3.4 0.0032 15.5 3.4 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 OEU10165.1 - 0.55 10.2 5.7 1 9.3 5.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FA_desaturase PF00487.24 OEU10166.1 - 6.6e-35 121.2 13.7 1.2e-34 120.3 13.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OEU10166.1 - 4.3e-16 58.8 2.3 5.9e-16 58.4 0.2 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 OEU10167.1 - 7e-59 199.3 0.0 1.2e-58 198.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OEU10167.1 - 4.1e-51 171.0 0.1 1.7e-19 69.7 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OEU10167.1 - 1.4e-27 96.6 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU10167.1 - 0.025 13.9 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OEU10167.1 - 0.027 14.4 0.0 0.23 11.3 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_21 PF05050.12 OEU10168.1 - 4.3e-06 26.9 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain GSIII_N PF12437.8 OEU10169.1 - 3.5e-52 176.3 0.3 7.9e-52 175.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 OEU10169.1 - 1.6e-25 89.3 0.0 2.8e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 OEU10169.1 - 5.1e-20 71.8 0.0 1.6e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain S1 PF00575.23 OEU10171.1 - 0.036 14.4 1.0 0.92 9.9 0.0 3.0 3 1 0 3 3 3 0 S1 RNA binding domain PDZ PF00595.24 OEU10172.1 - 4.6e-06 26.9 0.2 7.1e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU10172.1 - 0.0018 18.1 0.3 0.0032 17.3 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU10172.1 - 0.063 13.6 0.5 0.12 12.7 0.4 1.5 1 1 0 1 1 1 0 PDZ domain Methyltransf_32 PF13679.6 OEU10173.1 - 4.4e-13 49.5 0.1 2.6e-12 47.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 OEU10173.1 - 0.0061 16.1 0.4 0.13 11.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase TRM13 MTS PF05175.14 OEU10173.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 OEU10173.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain KIP1 PF07765.12 OEU10176.1 - 0.096 12.8 0.1 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 KIP1-like protein RRF PF01765.19 OEU10177.1 - 5.3e-36 124.0 0.5 5.3e-36 124.0 0.5 1.6 2 0 0 2 2 2 1 Ribosome recycling factor Fungus-induced PF10917.8 OEU10177.1 - 0.13 12.6 1.4 0.4 11.0 1.4 1.8 1 0 0 1 1 1 0 Fungus-induced protein FTO_NTD PF12933.7 OEU10178.1 - 4.5e-54 183.6 0.2 1.9e-53 181.6 0.2 2.0 1 1 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.7 OEU10178.1 - 1.2e-21 77.3 12.4 9.9e-20 71.0 12.4 2.7 1 1 0 1 1 1 1 FTO C-terminal domain ASCH PF04266.14 OEU10178.1 - 0.0057 17.2 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 ASCH domain U1snRNP70_N PF12220.8 OEU10178.1 - 6.7 7.4 16.8 1.2 9.8 2.0 3.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Isochorismatase PF00857.20 OEU10179.1 - 2.2e-26 93.1 0.0 2.5e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Methyltransf_31 PF13847.6 OEU10180.1 - 3.5e-09 36.6 0.3 6.7e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU10180.1 - 4.1e-09 36.2 0.6 1.2e-06 28.2 0.2 2.3 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 OEU10180.1 - 1.4e-08 34.5 0.3 2e-08 34.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OEU10180.1 - 3.9e-07 30.7 0.2 1.3e-06 29.1 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU10180.1 - 1.3e-05 25.8 0.2 3.9e-05 24.2 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 OEU10180.1 - 1.5e-05 24.8 1.8 0.024 14.4 2.2 2.9 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 OEU10180.1 - 0.00016 21.4 0.0 0.09 12.4 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 PCMT PF01135.19 OEU10180.1 - 0.00017 21.4 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OEU10180.1 - 0.0002 20.8 0.3 0.00035 20.0 0.3 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GRP PF07172.11 OEU10180.1 - 0.00032 21.3 3.9 0.00055 20.6 3.9 1.3 1 0 0 1 1 1 1 Glycine rich protein family Methyltransf_12 PF08242.12 OEU10180.1 - 0.0015 19.3 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU10180.1 - 0.0026 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU10180.1 - 0.0054 16.6 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 OEU10180.1 - 0.006 16.1 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa N6_Mtase PF02384.16 OEU10180.1 - 0.0088 15.3 0.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 1 N-6 DNA Methylase Methyltransf_15 PF09445.10 OEU10180.1 - 0.0094 15.5 0.1 0.019 14.5 0.1 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OEU10180.1 - 0.012 15.3 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FXMRP1_C_core PF12235.8 OEU10180.1 - 0.02 15.5 2.4 0.034 14.8 2.4 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Methyltransf_18 PF12847.7 OEU10180.1 - 0.024 14.6 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 OEU10180.1 - 0.033 13.7 0.0 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 CMAS PF02353.20 OEU10180.1 - 0.037 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OEU10180.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Lysine methyltransferase FoP_duplication PF13865.6 OEU10180.1 - 0.86 10.2 11.7 1.6 9.4 11.7 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HMG_box PF00505.19 OEU10181.1 - 2.1e-11 44.0 0.0 2.4e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU10181.1 - 3.4e-09 37.1 0.0 4e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 HMG-box domain Peptidase_M11 PF05548.11 OEU10182.1 - 5e-14 52.2 1.9 8e-14 51.5 1.7 1.5 1 1 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M10 PF00413.24 OEU10182.1 - 0.0011 18.9 0.6 0.0029 17.5 0.2 2.0 2 1 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 OEU10182.1 - 0.0033 17.1 0.1 0.0087 15.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OEU10182.1 - 0.0036 16.3 1.1 0.017 14.1 0.2 2.2 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_3 PF13582.6 OEU10182.1 - 0.0046 17.5 0.2 0.017 15.7 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ShK PF01549.24 OEU10182.1 - 2 9.0 8.3 8.2 7.1 8.3 2.1 1 1 0 1 1 1 0 ShK domain-like HMG_box PF00505.19 OEU10183.1 - 1.9e-09 37.8 0.7 2.7e-09 37.3 0.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU10183.1 - 1.2e-05 25.8 0.5 1.6e-05 25.4 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain DUF4096 PF13340.6 OEU10183.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) HAT PF02184.16 OEU10184.1 - 1.5e-18 66.5 41.1 0.00011 22.0 0.4 12.0 14 0 0 14 14 12 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OEU10184.1 - 1.4e-17 62.8 22.3 0.00017 22.1 0.1 11.9 7 4 6 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 OEU10184.1 - 2.2e-12 47.3 0.4 0.016 15.7 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat Suf PF05843.14 OEU10184.1 - 1.4e-11 45.0 10.0 0.0088 16.1 0.3 6.7 3 2 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 OEU10184.1 - 6e-08 32.2 7.9 0.017 14.3 0.1 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10184.1 - 2.3e-07 30.4 14.1 0.37 11.0 0.2 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU10184.1 - 1.6e-06 28.1 11.3 0.062 13.7 0.2 7.5 10 0 0 10 10 8 2 Tetratricopeptide repeat NRDE-2 PF08424.10 OEU10184.1 - 2.9e-06 26.6 15.2 0.015 14.4 0.0 5.7 2 2 4 6 6 6 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 OEU10184.1 - 4.5e-06 26.7 10.8 0.14 12.1 0.6 5.2 4 1 0 5 5 5 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 OEU10184.1 - 0.00088 19.3 7.8 3 8.3 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 OEU10184.1 - 0.00091 19.2 6.9 0.011 15.7 1.1 3.7 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 OEU10184.1 - 0.0042 17.7 6.7 0.33 11.6 0.1 5.8 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10184.1 - 0.012 16.2 12.0 62 4.5 0.1 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10184.1 - 0.028 14.4 2.0 26 5.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OEU10184.1 - 0.035 14.2 4.0 0.065 13.4 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU10184.1 - 0.039 14.2 0.3 0.039 14.2 0.3 5.5 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10184.1 - 0.047 13.5 2.5 1.9 8.5 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU10184.1 - 0.16 11.9 0.2 0.16 11.9 0.2 5.7 8 0 0 8 8 7 0 Tetratricopeptide repeat NOA36 PF06524.12 OEU10184.1 - 0.8 9.0 13.9 1.2 8.4 13.9 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OEU10184.1 - 1.5 8.5 14.8 2.9 7.5 14.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein U3_assoc_6 PF08640.11 OEU10184.1 - 1.7 8.7 17.1 2.4 8.3 0.4 5.9 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 Rhodanese_C PF12368.8 OEU10185.1 - 6.1e-11 42.5 8.1 6.1e-11 42.5 8.1 2.6 2 0 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 OEU10185.1 - 3.3e-08 33.8 0.0 6e-07 29.7 0.0 2.8 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OEU10185.1 - 9.1e-06 26.2 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FrhB_FdhB_C PF04432.13 OEU10185.1 - 0.054 13.3 0.3 0.054 13.3 0.3 2.4 2 1 1 3 3 3 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus SUIM_assoc PF16619.5 OEU10185.1 - 0.23 11.6 7.3 1.8 8.7 7.3 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RVT_1 PF00078.27 OEU10186.1 - 2.1e-07 30.7 0.0 7.1e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU10186.1 - 0.015 16.0 0.6 0.059 14.1 0.6 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 OEU10186.1 - 0.016 14.7 0.0 0.045 13.3 0.0 1.8 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family YvrJ PF12841.7 OEU10186.1 - 0.4 10.3 1.5 3.3 7.3 0.1 2.5 2 0 0 2 2 2 0 YvrJ protein family FMO-like PF00743.19 OEU10190.1 - 2.9e-18 65.6 0.0 3.6e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OEU10190.1 - 0.00049 19.5 0.2 0.4 9.9 0.0 2.8 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU10190.1 - 0.001 18.3 0.1 0.08 12.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OEU10190.1 - 0.013 14.8 0.4 0.73 9.0 0.4 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 OEU10190.1 - 0.071 13.5 0.1 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PDZ_6 PF17820.1 OEU10191.1 - 4.7e-07 29.5 4.6 0.11 12.4 0.0 5.2 5 0 0 5 5 5 3 PDZ domain Pep_deformylase PF01327.21 OEU10192.1 - 5.6e-22 78.0 0.0 1.7e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 Polypeptide deformylase Phage-Gp8 PF09215.10 OEU10192.1 - 0.0095 15.0 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage T4, Gp8 Tcp10_C PF07202.13 OEU10193.1 - 8.8e-14 51.8 0.0 8.8e-14 51.8 0.0 3.3 3 2 0 3 3 3 1 T-complex protein 10 C-terminus HAP1_N PF04849.13 OEU10193.1 - 0.00083 18.6 8.1 0.0018 17.5 8.1 1.6 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Osmo_CC PF08946.10 OEU10193.1 - 0.0077 16.5 2.3 0.011 15.9 0.6 2.2 2 0 0 2 2 2 1 Osmosensory transporter coiled coil ATP-synt_B PF00430.18 OEU10193.1 - 0.46 10.6 4.6 0.47 10.5 3.4 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2564 PF10819.8 OEU10193.1 - 3.7 8.0 9.2 1.5 9.3 1.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2564) IQ PF00612.27 OEU10194.1 - 1.8e-61 198.2 166.5 0.0059 16.3 0.8 34.8 34 1 0 35 35 35 30 IQ calmodulin-binding motif CH PF00307.31 OEU10194.1 - 2.6e-17 63.0 0.0 2.8e-07 30.7 0.0 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OEU10194.1 - 1e-08 34.9 0.2 7.9e-06 25.6 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain ANAPC4 PF12896.7 OEU10195.1 - 8.6e-14 51.5 1.0 1.7e-13 50.6 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 OEU10195.1 - 5.4e-06 26.6 0.1 0.0002 21.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain UDPGP PF01704.18 OEU10196.1 - 2.4e-13 49.5 0.0 4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Lipocalin_2 PF08212.12 OEU10198.1 - 5.2e-05 23.2 0.0 0.005 16.8 0.0 2.2 2 0 0 2 2 2 2 Lipocalin-like domain Lipocalin PF00061.23 OEU10198.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Epimerase PF01370.21 OEU10199.1 - 6e-55 186.3 0.0 8.6e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU10199.1 - 2e-18 66.9 0.6 1.1e-17 64.4 0.6 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OEU10199.1 - 4.5e-07 29.3 0.3 4.1e-05 22.9 0.0 2.5 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU10199.1 - 2.4e-05 23.6 0.0 5.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OEU10199.1 - 0.00079 18.5 0.1 0.0058 15.7 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ESAG1 PF03238.13 OEU10199.1 - 0.033 13.6 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 ESAG protein NAD_binding_4 PF07993.12 OEU10199.1 - 0.098 11.8 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Suf PF05843.14 OEU10200.1 - 1.4e-18 68.0 1.3 5.2e-13 49.6 0.0 3.6 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OEU10200.1 - 0.045 14.6 0.3 18 6.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 OEU10201.1 - 8.5e-18 65.0 0.1 3.6e-17 63.0 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU10201.1 - 0.00062 20.2 0.0 0.0017 18.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily OPA3 PF07047.12 OEU10202.1 - 8.7e-27 93.4 0.5 1e-26 93.2 0.5 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FtsK_alpha PF17854.1 OEU10202.1 - 0.0067 16.6 0.3 3 8.0 0.1 2.1 2 0 0 2 2 2 2 FtsK alpha domain Pro_isomerase PF00160.21 OEU10203.1 - 1.9e-17 64.0 0.0 5.4e-17 62.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OppC_N PF12911.7 OEU10203.1 - 0.091 12.8 0.7 0.18 11.8 0.7 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Ribosomal_L28 PF00830.19 OEU10205.1 - 1.1e-19 70.4 0.1 1.2e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L28 family zf-MYND PF01753.18 OEU10206.1 - 4.9e-05 23.3 12.4 4.9e-05 23.3 12.4 2.2 2 1 0 2 2 2 1 MYND finger AIM24 PF01987.17 OEU10207.1 - 1.1e-37 129.8 0.1 1.3e-37 129.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 HSF_DNA-bind PF00447.17 OEU10209.1 - 8.9e-18 64.7 0.1 9.9e-18 64.6 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding RhoGAP PF00620.27 OEU10210.1 - 1e-15 57.9 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 OEU10210.1 - 3.1e-09 36.7 0.0 5.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRS1 PF04939.12 OEU10212.1 - 5e-32 111.0 3.2 5e-32 111.0 3.2 4.3 4 0 0 4 4 4 2 Ribosome biogenesis regulatory protein (RRS1) Pkinase PF00069.25 OEU10213.1 - 7.2e-40 137.0 0.0 1.6e-38 132.6 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10213.1 - 5.3e-16 58.7 0.0 1e-14 54.4 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU10213.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SUIM_assoc PF16619.5 OEU10214.1 - 1.3 9.2 8.4 0.22 11.6 4.1 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cwf_Cwc_15 PF04889.12 OEU10214.1 - 4.6 6.9 26.9 4.3 7.0 19.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BIRC6 PF12356.8 OEU10214.1 - 5.8 6.3 12.7 0.18 11.2 6.0 1.9 3 0 0 3 3 3 0 Baculoviral IAP repeat-containing protein 6 Golgin_A5 PF09787.9 OEU10215.1 - 5.1e-12 45.9 12.4 5.1e-12 45.9 12.4 3.8 1 1 2 3 3 3 1 Golgin subfamily A member 5 P63C PF10546.9 OEU10215.1 - 3.3 8.4 7.4 0.25 12.0 0.9 2.5 2 0 0 2 2 2 0 P63C domain Sulfotransfer_3 PF13469.6 OEU10217.1 - 7e-07 29.8 0.2 9.2e-05 22.9 0.2 2.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 OEU10217.1 - 3.2e-05 23.9 0.0 8.7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 OEU10217.1 - 0.011 15.3 0.0 0.034 13.6 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase domain TMCO5 PF14992.6 OEU10217.1 - 0.28 10.7 2.1 0.72 9.4 1.0 2.0 2 0 0 2 2 2 0 TMCO5 family Fasciclin PF02469.22 OEU10218.1 - 9.7e-21 74.3 0.0 1.1e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain RGI1 PF10843.8 OEU10218.1 - 0.0084 15.8 0.6 0.01 15.5 0.6 1.0 1 0 0 1 1 1 1 Respiratory growth induced protein 1 DnaJ PF00226.31 OEU10220.1 - 1.5e-23 82.7 0.2 1.7e-23 82.5 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain Lig_chan PF00060.26 OEU10223.1 - 1.8e-08 34.3 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OEU10223.1 - 0.00033 20.2 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF3671 PF12420.8 OEU10223.1 - 0.0082 16.2 0.5 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function ABC_trans_CmpB PF06541.11 OEU10223.1 - 0.34 11.1 2.9 1.7 8.9 0.1 3.2 3 1 0 3 3 3 0 Putative ABC-transporter type IV DUF3413 PF11893.8 OEU10223.1 - 4.5 6.4 7.4 2.5 7.2 1.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3413) Transposase_mut PF00872.18 OEU10225.1 - 0.039 12.8 0.4 0.072 11.9 0.4 1.4 1 0 0 1 1 1 0 Transposase, Mutator family GrpB PF04229.14 OEU10225.1 - 0.13 12.5 0.7 0.23 11.7 0.7 1.4 1 0 0 1 1 1 0 GrpB protein Rieske PF00355.26 OEU10226.1 - 5.7e-11 42.2 0.0 9.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 OEU10226.1 - 3.4e-09 37.1 0.3 6.2e-09 36.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region IBR PF01485.21 OEU10227.1 - 0.0078 16.4 8.8 0.0078 16.4 8.8 3.3 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain CDH1_2_SANT_HL1 PF18375.1 OEU10227.1 - 0.018 15.7 1.9 2.7 8.7 0.0 2.9 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Phasin PF05597.11 OEU10227.1 - 0.17 11.9 4.3 0.36 10.8 0.6 3.1 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CobN-Mg_chel PF02514.16 OEU10228.1 - 0 1364.0 0.0 0 1363.7 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase AAA_lid_2 PF17863.1 OEU10229.1 - 1e-19 70.1 0.3 2.4e-19 69.0 0.3 1.6 1 0 0 1 1 1 1 AAA lid domain VWA_2 PF13519.6 OEU10229.1 - 1.1e-16 61.4 0.1 8.3e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 OEU10229.1 - 1.7e-11 43.9 0.0 1.9e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA PF00092.28 OEU10229.1 - 4.7e-08 33.5 0.0 1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 OEU10229.1 - 3.8e-07 30.2 0.0 0.00086 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OEU10229.1 - 0.00037 20.2 0.0 0.0054 16.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain VWA_CoxE PF05762.14 OEU10229.1 - 0.00039 19.9 0.2 0.00039 19.9 0.2 1.6 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein MCM PF00493.23 OEU10229.1 - 0.004 16.3 0.0 0.041 13.0 0.0 2.5 2 1 0 2 2 2 1 MCM P-loop domain VWA_3 PF13768.6 OEU10229.1 - 0.045 13.7 1.1 0.098 12.6 0.1 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain phage_tail_N PF08400.10 OEU10229.1 - 0.062 13.3 0.1 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 Prophage tail fibre N-terminal Silic_transp PF03842.13 OEU10230.1 - 4.8 5.4 8.3 5.7 5.1 8.3 1.1 1 0 0 1 1 1 0 Silicon transporter AMP-binding PF00501.28 OEU10230.1 - 8.3 4.9 7.9 8.8 4.8 7.1 1.3 1 1 0 1 1 1 0 AMP-binding enzyme DNA_pol_phi PF04931.13 OEU10230.1 - 9.8 4.1 21.6 13 3.7 21.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M11 PF05548.11 OEU10231.1 - 2.9e-18 66.1 0.1 4.4e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_3 PF13582.6 OEU10231.1 - 0.00027 21.4 0.5 0.0063 17.0 0.0 2.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU10231.1 - 0.0014 18.5 0.1 0.0036 17.2 0.0 1.9 3 0 0 3 3 3 1 Matrixin Reprolysin_5 PF13688.6 OEU10231.1 - 0.019 15.1 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12 MRC1 PF09444.10 OEU10231.1 - 0.68 10.4 3.9 1.2 9.7 3.9 1.3 1 0 0 1 1 1 0 MRC1-like domain Imm9 PF15587.6 OEU10232.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 9 Dimerisation PF08100.11 OEU10232.1 - 0.14 12.2 0.2 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Dimerisation domain Ketoacyl-synt_C PF02801.22 OEU10233.1 - 1e-25 90.0 0.9 1.5e-25 89.5 0.9 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 OEU10233.1 - 1.1e-13 51.4 0.1 2.3e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 OEU10233.1 - 0.018 15.5 0.0 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Phage_base_V PF04717.12 OEU10233.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector HNH_2 PF13391.6 OEU10234.1 - 0.014 15.5 0.4 0.031 14.4 0.1 1.9 2 1 0 2 2 2 0 HNH endonuclease PQQ_2 PF13360.6 OEU10235.1 - 7.9e-11 42.0 0.8 6.5e-09 35.7 0.0 3.5 3 1 2 5 5 5 1 PQQ-like domain PQQ_3 PF13570.6 OEU10235.1 - 0.00011 22.5 3.2 0.58 10.7 0.0 5.7 6 0 0 6 6 6 1 PQQ-like domain PQQ PF01011.21 OEU10235.1 - 0.00014 21.6 0.0 6.8 6.8 0.0 4.0 3 0 0 3 3 3 2 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 OEU10235.1 - 0.013 15.8 0.0 0.15 12.4 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF521 PF04412.13 OEU10237.1 - 3.3e-106 355.4 0.0 6.9e-105 351.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 OEU10237.1 - 3.3e-28 97.3 0.0 6.7e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain DUF871 PF05913.11 OEU10238.1 - 0.16 11.2 0.1 0.57 9.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF871) Yip1 PF04893.17 OEU10239.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain PAT1 PF09770.9 OEU10239.1 - 0.19 10.0 13.5 0.24 9.6 13.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 OEU10239.1 - 3.3 7.6 25.5 4.9 7.0 25.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_5 PF00266.19 OEU10240.1 - 3.3e-49 167.8 0.0 3.9e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OEU10240.1 - 0.088 12.1 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.28 OEU10242.1 - 1.1e-74 251.6 0.1 1.4e-74 251.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Antimicrobial_7 PF08102.11 OEU10242.1 - 0.064 13.5 0.6 0.15 12.3 0.6 1.6 1 0 0 1 1 1 0 Scorpion antimicrobial peptide zf-C2H2_assoc2 PF16624.5 OEU10243.1 - 0.063 14.3 0.7 0.1 13.6 0.7 1.3 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger tRNA-synt_1 PF00133.22 OEU10245.1 - 7.1e-192 638.8 0.1 8.8e-191 635.2 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OEU10245.1 - 8.3e-38 129.7 0.0 1.4e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OEU10245.1 - 2.5e-23 82.5 0.2 7.2e-08 31.6 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 OEU10245.1 - 1.2e-19 70.4 6.3 6.1e-19 68.1 7.0 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 OEU10245.1 - 3.2e-12 46.3 0.1 6.6e-10 38.8 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 OEU10245.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 OEU10245.1 - 0.085 12.2 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain 2OG-FeII_Oxy_3 PF13640.6 OEU10246.1 - 0.099 13.6 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily HSP70 PF00012.20 OEU10247.1 - 3.9e-74 249.9 5.1 8.4e-71 238.9 0.0 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OEU10247.1 - 8.3e-15 54.4 0.0 2.4e-13 49.6 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OEU10247.1 - 0.0021 18.4 0.0 0.048 14.1 0.0 2.7 2 1 0 2 2 2 1 Cell division protein FtsA BcrAD_BadFG PF01869.20 OEU10247.1 - 0.0025 17.3 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 OEU10247.1 - 0.0066 15.7 0.0 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 StbA protein DUF547 PF04784.14 OEU10248.1 - 4.1e-25 88.2 0.1 2.8e-24 85.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF547 PH PF00169.29 OEU10248.1 - 0.00013 22.4 0.0 0.00076 20.0 0.0 2.4 2 0 0 2 2 2 1 PH domain Corona_nucleoca PF00937.18 OEU10248.1 - 5.8 5.8 7.2 0.3 10.1 0.7 1.9 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF382 PF04037.13 OEU10250.1 - 6.5e-50 168.5 0.1 8.8e-50 168.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 OEU10250.1 - 2.8e-15 55.9 4.3 5.5e-15 55.0 4.3 1.5 1 0 0 1 1 1 1 PSP HSP70 PF00012.20 OEU10251.1 - 2.8e-250 831.7 3.5 3.3e-250 831.4 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OEU10251.1 - 7.7e-18 64.4 0.1 2.7e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 OEU10251.1 - 0.011 15.0 4.0 0.02 14.2 4.0 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Hydantoinase_A PF01968.18 OEU10251.1 - 0.047 13.0 0.4 0.17 11.1 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Aldo_ket_red PF00248.21 OEU10252.1 - 5.2e-35 121.1 0.0 7.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Rotamase PF00639.21 OEU10253.1 - 7e-17 62.2 0.0 8.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OEU10253.1 - 6.7e-13 49.2 0.0 1.2e-12 48.4 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU10253.1 - 0.0011 19.8 0.0 0.0011 19.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ser_hydrolase PF06821.13 OEU10255.1 - 4.9e-07 29.8 0.0 6.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 OEU10255.1 - 9.4e-06 25.1 0.1 0.016 14.5 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OEU10255.1 - 4.6e-05 23.2 0.0 6.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OEU10255.1 - 0.00013 22.7 0.0 0.00035 21.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OEU10255.1 - 0.0018 17.9 0.3 1.4 8.4 0.1 2.1 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 OEU10255.1 - 0.0018 17.9 0.1 0.058 13.0 0.0 2.5 1 1 2 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OEU10255.1 - 0.032 14.1 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OEU10255.1 - 0.05 13.4 0.0 6.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 OEU10255.1 - 0.058 13.3 0.0 0.093 12.6 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.8 OEU10255.1 - 0.24 10.9 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) APH PF01636.23 OEU10256.1 - 7.3e-14 52.3 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU10256.1 - 0.02 14.3 0.6 0.047 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 OEU10256.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 OEU10256.1 - 0.084 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Topoisom_bac PF01131.20 OEU10257.1 - 2.1e-98 330.0 0.0 2.9e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OEU10257.1 - 1.3e-14 54.3 0.0 2.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 OEU10257.1 - 0.084 13.4 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 Toprim domain Arylesterase PF01731.20 OEU10258.1 - 0.0095 16.1 0.6 1.6 9.0 0.0 4.0 4 0 0 4 4 4 1 Arylesterase DPM3 PF08285.11 OEU10258.1 - 0.21 11.8 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) zf-MYND PF01753.18 OEU10259.1 - 7.1e-12 45.2 16.1 1.4e-11 44.3 16.1 1.5 1 0 0 1 1 1 1 MYND finger DUF2614 PF11023.8 OEU10259.1 - 0.068 13.3 2.1 0.11 12.5 2.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-C6H2 PF15801.5 OEU10259.1 - 0.092 13.1 15.3 0.21 11.9 15.3 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 OEU10259.1 - 0.39 10.9 10.7 1.2 9.3 10.4 2.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CSD PF00313.22 OEU10260.1 - 7.1e-14 51.4 0.1 1.2e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU10260.1 - 0.011 15.4 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain W2 PF02020.18 OEU10261.1 - 1.3e-11 44.5 3.1 4.2e-11 42.8 3.1 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OEU10261.1 - 1.7e-09 37.0 7.4 1.7e-05 24.4 1.2 3.7 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 OEU10261.1 - 0.00034 19.7 0.4 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 1 L-fucokinase NTP_transferase PF00483.23 OEU10261.1 - 0.00053 19.7 0.0 0.0019 17.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase DUF4954 PF16314.5 OEU10261.1 - 0.015 13.5 4.6 0.018 13.2 3.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 OEU10261.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OEU10261.1 - 0.29 10.9 13.5 0.034 13.9 2.1 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase WD40 PF00400.32 OEU10262.1 - 4.9e-18 65.1 13.2 4.9e-07 30.3 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU10262.1 - 0.00022 21.5 0.0 0.053 13.8 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Presenilin PF01080.17 OEU10262.1 - 0.3 9.8 4.1 0.45 9.2 4.1 1.5 1 0 0 1 1 1 0 Presenilin CAML PF14963.6 OEU10262.1 - 0.61 10.2 3.4 1.3 9.1 3.4 1.6 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Mucin PF01456.17 OEU10262.1 - 0.85 9.6 22.5 4.1 7.4 3.4 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein NARP1 PF12569.8 OEU10262.1 - 1.8 7.4 5.4 2.7 6.8 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3439 PF11921.8 OEU10262.1 - 1.9 8.4 12.2 0.6 10.1 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) SRP-alpha_N PF04086.13 OEU10263.1 - 0.064 13.2 1.4 0.064 13.2 1.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal bZIP_1 PF00170.21 OEU10265.1 - 1.8e-09 37.5 3.9 2e-09 37.4 3.9 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU10265.1 - 7.4e-06 26.0 6.0 9.8e-06 25.6 6.0 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU10265.1 - 0.0024 18.4 3.1 0.0027 18.2 3.1 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor Tup_N PF08581.10 OEU10265.1 - 0.0089 16.3 0.1 0.0098 16.2 0.1 1.3 1 1 0 1 1 1 1 Tup N-terminal Anillin_N PF16018.5 OEU10265.1 - 0.022 15.4 0.3 0.024 15.2 0.3 1.2 1 0 0 1 1 1 0 Anillin N-terminus MIP-T3_C PF17749.1 OEU10265.1 - 0.036 14.0 0.6 0.041 13.9 0.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region HetR_C PF18460.1 OEU10265.1 - 0.037 14.0 1.2 0.045 13.7 1.2 1.1 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain WD40_alt PF14077.6 OEU10265.1 - 0.068 13.1 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif Nuc_N PF14448.6 OEU10265.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Nuclease N terminal DUF4140 PF13600.6 OEU10265.1 - 0.33 11.4 2.6 0.79 10.2 2.6 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.21 OEU10266.1 - 5.1e-09 36.1 2.6 5.1e-09 36.1 2.6 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OEU10266.1 - 3.2e-07 30.3 3.2 1.2e-06 28.5 3.2 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU10266.1 - 0.049 14.1 2.5 0.049 14.1 2.5 3.0 4 0 0 4 4 4 0 bZIP Maf transcription factor Sas10_Utp3 PF04000.15 OEU10266.1 - 1.4 9.6 6.5 0.5 11.0 0.2 2.6 2 1 0 2 2 2 0 Sas10/Utp3/C1D family DUF4407 PF14362.6 OEU10266.1 - 3.4 6.9 7.8 2.7 7.3 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Miga PF10265.9 OEU10266.1 - 7.3 5.4 14.4 0.11 11.4 7.5 1.4 2 0 0 2 2 2 0 Mitoguardin NfeD PF01957.18 OEU10267.1 - 0.043 14.2 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Gaa1 PF04114.14 OEU10269.1 - 2.1e-25 89.7 5.5 3.3e-25 89.1 3.4 2.3 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component Glyco_hydro_129 PF11308.8 OEU10269.1 - 0.05 12.8 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 Spt20 PF12090.8 OEU10269.1 - 1.5 8.4 12.0 0.36 10.4 3.6 2.7 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 OEU10269.1 - 1.5 7.7 10.1 1.6 7.6 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SPOUT_MTase PF02590.17 OEU10270.1 - 0.033 14.2 0.1 0.17 11.8 0.0 1.8 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase NDUF_C2 PF06374.11 OEU10270.1 - 0.068 13.3 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TPR_12 PF13424.6 OEU10272.1 - 2.9e-100 328.7 18.5 5.9e-15 55.3 0.0 8.2 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 OEU10272.1 - 3.5e-55 182.5 7.4 1.7e-07 30.9 0.0 12.4 12 2 1 13 13 13 8 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10272.1 - 5.9e-46 152.5 0.8 3.9e-05 23.3 0.3 11.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10272.1 - 8.8e-40 131.6 4.1 0.0031 17.5 0.2 12.4 13 1 0 13 13 13 8 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10272.1 - 7.2e-36 119.6 6.6 0.0005 19.9 0.0 12.1 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.6 OEU10272.1 - 3.2e-34 114.3 4.1 0.0072 16.5 0.0 11.8 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU10272.1 - 1.2e-21 77.5 0.8 3.2e-07 30.0 0.0 4.7 1 1 1 4 4 4 4 MalT-like TPR region TPR_11 PF13414.6 OEU10272.1 - 2e-15 56.2 8.6 0.27 10.9 0.0 9.2 10 0 0 10 10 10 5 TPR repeat TPR_14 PF13428.6 OEU10272.1 - 8.8e-15 54.1 2.9 3.8 8.6 0.0 9.4 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10272.1 - 1.1e-12 47.7 5.8 0.27 11.9 0.0 9.1 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU10272.1 - 1.1e-10 42.0 5.8 1.8 9.3 0.1 7.2 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 OEU10272.1 - 9.8e-09 35.0 0.0 1.6 9.3 0.0 8.7 11 0 0 11 11 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU10272.1 - 9.4e-08 31.4 3.1 0.061 12.8 0.0 6.2 6 0 0 6 6 6 1 SHNi-TPR SNAP PF14938.6 OEU10272.1 - 5.9e-07 29.2 0.2 0.037 13.5 0.0 4.4 4 1 1 5 5 5 2 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 OEU10272.1 - 8.4e-06 25.7 1.1 0.5 10.1 0.1 4.5 3 2 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 OEU10272.1 - 2.7e-05 24.2 1.7 0.91 9.7 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU10272.1 - 4.6e-05 23.8 4.8 1.1 9.8 0.1 5.8 6 1 1 7 7 6 1 Tetratricopeptide repeat MIT PF04212.18 OEU10272.1 - 0.00035 20.6 8.0 18 5.5 0.0 6.8 7 1 1 8 8 8 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 OEU10272.1 - 0.0016 18.4 4.6 3.3 7.8 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 OEU10272.1 - 0.0027 17.4 2.8 10 5.8 0.1 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 OEU10272.1 - 0.0028 17.4 5.8 4.4 7.0 0.1 5.5 3 3 2 6 6 6 1 26S proteasome subunit RPN7 TPR_5 PF12688.7 OEU10272.1 - 0.0095 16.2 0.5 2.6 8.3 0.0 3.8 3 1 0 3 3 3 1 Tetratrico peptide repeat Pou PF00157.17 OEU10272.1 - 0.12 12.4 0.2 26 4.8 0.0 4.0 3 1 1 4 4 4 0 Pou domain - N-terminal to homeobox domain DUF5475 PF17569.2 OEU10272.1 - 0.12 12.7 0.2 6.2 7.2 0.0 3.5 4 0 0 4 4 3 0 Family of unknown function (DUF5475) ANAPC5 PF12862.7 OEU10272.1 - 0.53 10.4 2.7 10 6.2 0.0 4.1 3 2 3 6 6 4 0 Anaphase-promoting complex subunit 5 CSRNP_N PF16019.5 OEU10273.1 - 0.067 13.1 7.8 0.52 10.2 4.2 2.7 2 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus VKG_Carbox PF05090.14 OEU10274.1 - 1.5e-06 27.4 13.0 5.7e-06 25.4 13.0 1.8 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase PolC_DP2 PF03833.13 OEU10274.1 - 0.18 9.6 0.1 0.25 9.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DoxX PF07681.12 OEU10274.1 - 0.78 10.4 10.0 0.032 14.8 3.1 2.3 2 1 0 2 2 2 0 DoxX DEAD PF00270.29 OEU10275.1 - 7.9e-16 58.3 0.0 1.7e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU10275.1 - 1.6e-14 54.1 0.0 2.2e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OEU10275.1 - 1.4e-07 31.7 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF21 PF01595.20 OEU10276.1 - 1.3e-28 99.9 0.2 2.2e-28 99.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OEU10276.1 - 3.6e-12 46.6 1.0 4.4e-06 27.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 OEU10276.1 - 0.0011 18.9 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NmrA PF05368.13 OEU10277.1 - 6.4e-26 91.3 0.2 9.3e-26 90.8 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OEU10277.1 - 1.2e-11 44.9 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OEU10277.1 - 0.028 13.9 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DTW PF03942.15 OEU10279.1 - 1.1e-19 71.0 6.9 4.9e-15 55.8 0.1 2.2 2 0 0 2 2 2 2 DTW domain DUF4056 PF13265.6 OEU10280.1 - 0.051 12.9 0.0 7.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4056) peroxidase PF00141.23 OEU10281.1 - 1.4e-31 110.0 0.0 1.7e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Malic_M PF03949.15 OEU10282.1 - 1.7e-99 332.3 0.1 2.3e-99 331.8 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OEU10282.1 - 9.2e-73 243.9 0.0 1.5e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Fasciclin PF02469.22 OEU10283.1 - 5.1e-14 52.6 0.1 2.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Trypan_PARP PF05887.11 OEU10283.1 - 6.3 6.8 24.0 11 6.0 24.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) His_Phos_1 PF00300.22 OEU10284.1 - 2.2e-21 76.4 0.0 7.9e-15 55.1 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 OEU10285.1 - 1.8e-24 86.3 13.6 1.8e-24 86.3 13.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3446 PF11928.8 OEU10285.1 - 0.018 15.4 4.4 0.094 13.0 4.4 2.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Glyco_transf_22 PF03901.17 OEU10286.1 - 5.6e-35 121.4 20.9 8.4e-35 120.8 20.9 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Hydrolase PF00702.26 OEU10287.1 - 8.7e-46 156.8 0.2 1.5e-45 156.1 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OEU10287.1 - 9.6e-42 142.5 1.0 9.6e-42 142.5 1.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 OEU10287.1 - 5.3e-22 78.0 0.0 1.8e-10 41.1 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OEU10287.1 - 4.5e-06 26.6 5.4 0.0043 16.8 0.4 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU10287.1 - 0.00082 19.8 0.0 0.0044 17.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OEU10287.1 - 0.039 14.1 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 OEU10287.1 - 0.069 13.1 0.2 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF678 PF05077.12 OEU10287.1 - 0.089 12.9 0.8 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DUF3947 PF13135.6 OEU10287.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) Hydrolase PF00702.26 OEU10288.1 - 8.6e-46 156.9 0.2 1.4e-45 156.1 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OEU10288.1 - 2.7e-42 144.3 0.7 2.7e-42 144.3 0.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 OEU10288.1 - 4.8e-22 78.2 0.0 1.7e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OEU10288.1 - 8.1e-07 29.0 0.6 0.0041 16.9 0.4 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU10288.1 - 0.00074 20.0 0.0 0.0042 17.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3947 PF13135.6 OEU10288.1 - 0.034 14.3 0.3 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Hydrolase_6 PF13344.6 OEU10288.1 - 0.044 13.9 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 OEU10288.1 - 0.067 13.2 0.2 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF678 PF05077.12 OEU10288.1 - 0.084 13.0 0.8 16 5.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Glyco_transf_28 PF03033.20 OEU10289.1 - 2.8e-10 40.4 0.0 3.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain zf-RING_10 PF16685.5 OEU10292.1 - 0.35 11.0 5.4 0.27 11.4 1.5 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 AZUL PF16558.5 OEU10293.1 - 0.14 12.4 3.4 5.1 7.4 0.1 3.1 3 0 0 3 3 3 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Enkurin PF13864.6 OEU10294.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.8 2 1 0 2 2 2 0 Calmodulin-binding TPR_MLP1_2 PF07926.12 OEU10294.1 - 0.23 11.5 10.7 0.89 9.6 5.9 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 OEU10294.1 - 0.68 10.2 9.2 0.21 11.9 1.3 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper UPF0242 PF06785.11 OEU10294.1 - 1.9 8.5 9.7 0.22 11.6 0.4 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Rep-A_N PF04057.12 OEU10295.1 - 2.2e-08 34.0 0.1 5.8e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.9 OEU10295.1 - 0.039 13.9 0.1 0.097 12.7 0.1 1.7 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD WW_FCH_linker PF16623.5 OEU10296.1 - 0.15 12.8 2.5 0.35 11.6 2.0 1.9 1 1 1 2 2 2 0 Unstructured linker region between on GAS7 protein Integrase_H2C2 PF17921.1 OEU10300.1 - 2.8e-11 43.3 5.1 4.9e-11 42.6 5.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OEU10300.1 - 0.004 17.3 2.1 0.0078 16.4 2.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RNase_T PF00929.24 OEU10302.1 - 0.0011 19.6 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease PPR_1 PF12854.7 OEU10303.1 - 8.3e-23 79.8 5.3 1.2e-07 31.3 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 OEU10303.1 - 4.7e-20 71.5 8.2 9.8e-09 35.3 1.1 5.5 4 2 1 5 5 5 3 PPR repeat family PPR PF01535.20 OEU10303.1 - 3.3e-19 67.7 10.4 5.2e-05 23.2 0.0 7.7 6 2 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 OEU10303.1 - 5.3e-12 45.6 10.6 4.5e-05 23.4 0.6 4.2 4 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU10303.1 - 0.00099 18.5 5.9 0.0056 16.1 0.0 3.1 3 2 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PET117 PF15786.5 OEU10303.1 - 4 7.8 11.3 0.67 10.3 7.0 2.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial UN_NPL4 PF11543.8 OEU10305.1 - 0.0073 16.8 0.3 0.14 12.7 0.0 2.8 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 R3H-assoc PF13902.6 OEU10306.1 - 2.9 8.3 14.7 7.3 7.0 0.0 2.7 3 0 0 3 3 3 0 R3H-associated N-terminal domain MFMR_assoc PF16596.5 OEU10307.1 - 0.034 14.6 1.0 0.057 13.9 1.0 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR DUF1218 PF06749.12 OEU10308.1 - 0.083 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Ank_2 PF12796.7 OEU10309.1 - 0.00025 21.6 0.0 0.022 15.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU10309.1 - 0.045 14.3 0.0 0.51 11.0 0.0 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf-MYND PF01753.18 OEU10310.1 - 5.1e-06 26.5 8.9 1.2e-05 25.3 8.9 1.6 1 0 0 1 1 1 1 MYND finger LRR_9 PF14580.6 OEU10311.1 - 0.0011 18.5 2.3 0.047 13.2 0.2 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OEU10311.1 - 0.048 14.1 0.5 0.048 14.1 0.5 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PepSY PF03413.19 OEU10311.1 - 0.075 13.6 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain LRR_8 PF13855.6 OEU10311.1 - 0.1 12.4 5.0 0.81 9.5 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat YbgT_YccB PF08173.11 OEU10312.1 - 0.34 11.1 3.1 2.7 8.2 0.3 2.6 2 0 0 2 2 2 0 Membrane bound YbgT-like protein DUF3754 PF12576.8 OEU10312.1 - 0.47 10.4 4.2 1.6 8.7 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3754) Suf PF05843.14 OEU10312.1 - 1.8 8.5 11.1 1.7 8.5 8.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4577 PF15145.6 OEU10313.1 - 0.011 15.7 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) SurA_N_3 PF13624.6 OEU10313.1 - 0.4 10.4 1.4 0.53 10.1 1.4 1.3 1 1 0 1 1 1 0 SurA N-terminal domain Myosin_head PF00063.21 OEU10314.1 - 0.0024 16.2 0.0 0.0033 15.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) YL1 PF05764.13 OEU10315.1 - 0.0014 18.8 7.9 0.0018 18.4 7.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein E1_UFD PF09358.10 OEU10317.1 - 0.0024 18.5 0.1 0.6 10.8 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin fold domain 7tm_3 PF00003.22 OEU10319.1 - 4.7e-17 62.5 26.6 6.6e-17 62.0 26.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DDE_Tnp_1_7 PF13843.6 OEU10320.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 F-box-like PF12937.7 OEU10322.1 - 9.7e-05 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU10322.1 - 0.00036 20.3 0.1 0.001 18.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OEU10322.1 - 0.00065 19.6 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box Syntaxin PF00804.25 OEU10323.1 - 0.079 12.6 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Syntaxin DUF5479 PF17575.2 OEU10324.1 - 0.059 13.9 0.0 0.078 13.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5479) Trypsin PF00089.26 OEU10326.1 - 3.5e-12 46.6 0.0 6.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin Spt20 PF12090.8 OEU10326.1 - 0.039 13.6 9.1 0.059 13.0 9.1 1.3 1 0 0 1 1 1 0 Spt20 family Ycf1 PF05758.12 OEU10326.1 - 0.13 10.1 0.7 0.17 9.7 0.7 1.2 1 0 0 1 1 1 0 Ycf1 PTPRCAP PF15713.5 OEU10326.1 - 1.2 9.5 18.1 1.8 8.8 12.0 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Autophagy_N PF03986.13 OEU10326.1 - 5.9 6.8 13.6 0.52 10.2 8.8 1.6 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain Nop14 PF04147.12 OEU10326.1 - 7.3 4.7 25.0 1.7 6.7 18.5 1.9 2 0 0 2 2 2 0 Nop14-like family PPP4R2 PF09184.11 OEU10326.1 - 7.5 6.0 25.6 6.9 6.2 16.8 2.1 2 0 0 2 2 2 0 PPP4R2 Conotoxin PF02950.17 OEU10326.1 - 8 7.6 7.3 93 4.1 0.0 2.4 2 0 0 2 2 2 0 Conotoxin SWIM PF04434.17 OEU10327.1 - 0.0027 17.4 0.7 0.0055 16.3 0.7 1.5 1 0 0 1 1 1 1 SWIM zinc finger PPR_1 PF12854.7 OEU10328.1 - 2.8e-77 254.1 0.1 1.8e-08 33.9 0.0 16.5 17 0 0 17 17 17 12 PPR repeat PPR_2 PF13041.6 OEU10328.1 - 3.4e-60 200.0 26.4 9.5e-10 38.5 0.0 13.9 10 7 3 13 13 13 11 PPR repeat family PPR PF01535.20 OEU10328.1 - 4.3e-55 180.2 25.5 4.5e-06 26.6 0.0 17.1 18 1 0 18 18 18 9 PPR repeat PPR_3 PF13812.6 OEU10328.1 - 8.5e-55 182.7 5.1 6.7e-06 26.1 0.0 13.5 8 6 5 13 13 13 13 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU10328.1 - 8.2e-36 123.4 0.5 5.4e-10 39.0 0.0 6.9 1 1 5 7 7 7 5 Pentacotripeptide-repeat region of PRORP Wzy_C_2 PF11846.8 OEU10328.1 - 2.8e-15 56.7 0.0 1.3 8.9 0.0 9.2 2 1 9 11 11 11 3 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 OEU10328.1 - 2.2e-10 40.4 1.4 4.6 8.3 0.0 8.6 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10328.1 - 6.9e-08 32.6 2.8 36 5.3 0.0 10.4 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU10328.1 - 8.2e-08 32.7 6.6 13 6.4 0.0 9.3 8 3 0 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU10328.1 - 2.5e-05 23.8 0.0 2.8 7.2 0.0 4.7 2 1 1 4 4 4 2 MalT-like TPR region TetR_C_8 PF14278.6 OEU10328.1 - 0.00086 19.4 5.5 21 5.3 0.0 7.3 9 1 0 9 9 8 0 Transcriptional regulator C-terminal region TPR_4 PF07721.14 OEU10328.1 - 0.0017 18.8 14.5 18 6.3 0.0 8.0 11 0 0 11 11 7 0 Tetratricopeptide repeat Vps54_N PF10475.9 OEU10328.1 - 0.015 14.6 0.3 53 3.0 0.0 4.9 5 1 1 6 6 6 0 Vacuolar-sorting protein 54, of GARP complex RPM2 PF08579.11 OEU10328.1 - 0.031 14.7 0.3 14 6.1 0.0 4.4 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4177 PF13783.6 OEU10328.1 - 0.053 13.8 3.3 4.7e+02 1.2 0.0 7.1 9 0 0 9 9 7 0 Domain of unknown function (DUF4177) DUF1722 PF08349.11 OEU10328.1 - 0.12 12.6 0.6 29 5.0 0.0 4.2 4 1 1 5 5 4 0 Protein of unknown function (DUF1722) Abhydrolase_9 PF10081.9 OEU10328.1 - 0.13 11.3 0.1 15 4.5 0.0 3.5 3 1 1 4 4 4 0 Alpha/beta-hydrolase family ENT PF03735.14 OEU10328.1 - 1.1 9.4 3.2 2.7e+02 1.7 0.0 5.2 7 0 0 7 7 5 0 ENT domain CRC_subunit PF08624.10 OEU10329.1 - 0.16 12.4 0.8 0.24 11.8 0.8 1.3 1 0 0 1 1 1 0 Chromatin remodelling complex Rsc7/Swp82 subunit Mur_ligase_C PF02875.21 OEU10331.1 - 0.003 17.8 0.0 0.0082 16.4 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain MTCP1 PF08991.10 OEU10332.1 - 2e-05 24.7 2.9 2e-05 24.7 2.9 2.4 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 OEU10332.1 - 0.0028 17.6 11.5 0.071 13.1 0.2 3.0 2 2 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 OEU10332.1 - 0.033 14.3 4.1 0.033 14.3 4.1 3.0 3 0 0 3 3 3 0 CHCH domain COX17 PF05051.13 OEU10332.1 - 0.1 13.0 11.7 0.47 10.9 3.0 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 OEU10332.1 - 3.4 8.0 15.5 6 7.2 0.3 3.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) GCK PF07802.11 OEU10332.1 - 7 7.1 10.4 10 6.6 2.9 2.6 2 1 0 2 2 2 0 GCK domain MFS_1 PF07690.16 OEU10334.1 - 2.2e-10 40.0 0.0 2.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 OEU10334.1 - 2.6e-09 36.0 0.8 3.2e-09 35.7 0.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 OEU10334.1 - 0.033 13.1 1.5 0.04 12.8 1.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4131 PF13567.6 OEU10335.1 - 0.24 11.1 1.5 0.31 10.7 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fasciclin PF02469.22 OEU10336.1 - 4.7e-22 78.6 1.1 7.7e-15 55.2 0.0 2.3 1 1 1 2 2 2 2 Fasciclin domain zf-CCHC_5 PF14787.6 OEU10337.1 - 0.0035 17.0 1.0 0.0035 17.0 1.0 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OEU10337.1 - 0.082 13.0 1.2 0.24 11.6 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 OEU10338.1 - 0.00011 22.0 0.1 0.00041 20.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OEU10338.1 - 0.00034 20.4 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OEU10338.1 - 0.011 15.6 0.1 0.032 14.1 0.1 1.7 1 0 0 1 1 1 0 F-box zf-RING_4 PF14570.6 OEU10339.1 - 4.7e-16 58.3 17.7 4.7e-16 58.3 17.7 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF4148 PF13663.6 OEU10339.1 - 2.7 8.3 5.3 35 4.7 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4148) 2OG-FeII_Oxy_2 PF13532.6 OEU10340.1 - 3.6e-21 76.2 0.9 3.6e-21 76.2 0.9 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.10 OEU10340.1 - 0.87 8.9 37.7 0.038 13.4 8.0 2.1 2 0 0 2 2 2 0 BUD22 DUF1547 PF07577.11 OEU10341.1 - 0.16 12.4 0.1 0.57 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) DUF3141 PF11339.8 OEU10342.1 - 0.1 11.0 0.2 0.19 10.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) zf-B_box PF00643.24 OEU10345.1 - 0.085 13.0 4.8 0.052 13.7 2.3 1.9 2 0 0 2 2 2 0 B-box zinc finger IQ PF00612.27 OEU10347.1 - 1.9e-13 48.9 22.2 0.0026 17.4 0.4 6.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif Peripla_BP_2 PF01497.18 OEU10347.1 - 0.011 15.3 0.5 5.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Periplasmic binding protein MISS PF15822.5 OEU10347.1 - 0.011 15.6 0.7 4.2 7.1 0.2 2.2 2 0 0 2 2 2 0 MAPK-interacting and spindle-stabilising protein-like DUF3421 PF11901.8 OEU10347.1 - 0.13 12.3 0.0 25 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) MRI PF15325.6 OEU10347.1 - 0.3 12.2 0.1 0.3 12.2 0.1 4.1 4 1 1 5 5 5 0 Modulator of retrovirus infection Mdv1 PF11542.8 OEU10347.1 - 2.1 8.4 5.8 20 5.3 0.4 4.3 5 0 0 5 5 5 0 Mitochondrial division protein 1 HA PF03457.14 OEU10349.1 - 3.3e-14 53.0 0.0 3.3e-14 53.0 0.0 3.9 5 0 0 5 5 5 1 Helicase associated domain Myb_DNA-binding PF00249.31 OEU10349.1 - 1e-07 32.0 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU10349.1 - 0.00071 19.4 1.4 0.00071 19.4 1.4 5.3 6 0 0 6 6 6 1 Myb DNA-binding like ETF_alpha PF00766.19 OEU10350.1 - 0.016 15.2 0.1 3.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain Carb_kinase PF01256.17 OEU10350.1 - 0.083 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Carbohydrate kinase NAD_binding_7 PF13241.6 OEU10350.1 - 0.097 13.1 0.0 0.23 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Glu_cyclase_2 PF05096.12 OEU10351.1 - 5e-33 114.6 10.8 4.7e-12 45.9 0.7 5.2 3 1 0 4 4 4 4 Glutamine cyclotransferase SpoIIP PF07454.11 OEU10351.1 - 0.00012 21.7 0.6 0.00012 21.7 0.6 2.5 3 0 0 3 3 3 1 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 OEU10351.1 - 0.0013 18.9 1.3 0.0013 18.9 1.3 2.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DUF3306 PF11748.8 OEU10351.1 - 0.097 13.6 0.2 0.097 13.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RPOL_N PF14700.6 OEU10351.1 - 0.3 10.5 14.4 1.2 8.5 0.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal DUF4228 PF14009.6 OEU10351.1 - 1.2 9.5 6.7 32 4.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Afi1 PF07792.12 OEU10351.1 - 2 8.9 28.5 0.055 14.0 3.2 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CSRNP_N PF16019.5 OEU10351.1 - 2.2 8.1 16.6 2.2 8.2 3.1 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FYDLN_acid PF09538.10 OEU10351.1 - 2.8 8.6 26.7 1.1 10.0 7.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF702 PF05142.12 OEU10351.1 - 4.3 7.8 10.2 4 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) FAM176 PF14851.6 OEU10351.1 - 4.3 7.0 24.9 1.8 8.2 7.0 3.1 3 0 0 3 3 3 0 FAM176 family Ndc1_Nup PF09531.10 OEU10351.1 - 4.7 5.8 7.8 6.4 5.3 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 OEU10351.1 - 5.3 6.6 21.3 0.43 10.2 13.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RPN2_C PF18004.1 OEU10351.1 - 7.9 6.4 26.1 0.49 10.3 2.9 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 OEU10351.1 - 8.1 5.7 24.5 0.49 9.7 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TcpS PF17456.2 OEU10353.1 - 0.45 10.6 4.6 0.55 10.3 4.0 1.5 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S DUF3523 PF12037.8 OEU10353.1 - 1.1 8.6 31.2 1.3 8.4 31.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF3107 PF11305.8 OEU10353.1 - 4.7 7.5 6.7 1 9.6 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Ank_2 PF12796.7 OEU10355.1 - 0.00035 21.1 0.0 0.009 16.6 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU10355.1 - 0.05 13.9 0.1 2 8.8 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeats (many copies) TetR PF13972.6 OEU10355.1 - 0.15 11.8 0.4 0.27 10.9 0.4 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor SR-25 PF10500.9 OEU10355.1 - 0.16 11.6 7.0 0.23 11.0 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3742 PF12553.8 OEU10356.1 - 0.036 14.2 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) WBP-1 PF11669.8 OEU10358.1 - 0.12 13.0 0.3 0.12 13.0 0.3 2.3 3 1 0 3 3 3 0 WW domain-binding protein 1 TMEM154 PF15102.6 OEU10358.1 - 0.16 11.9 0.5 1 9.2 0.0 2.4 2 1 0 2 2 2 0 TMEM154 protein family zf-C3HC4_3 PF13920.6 OEU10360.1 - 0.0008 19.2 12.4 0.0015 18.3 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU10360.1 - 0.011 15.7 14.8 0.025 14.6 14.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU10360.1 - 0.017 14.9 12.3 0.037 13.9 12.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-TFIIB PF13453.6 OEU10360.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF1272 PF06906.11 OEU10360.1 - 0.51 10.5 9.4 1.2 9.3 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 OEU10360.1 - 0.67 9.9 6.0 1.3 9.0 6.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OEU10360.1 - 1.5 9.2 13.4 3 8.2 13.4 1.5 1 0 0 1 1 1 0 Ring finger domain DnaJ PF00226.31 OEU10361.1 - 2.6e-11 43.5 0.2 2.6e-11 43.5 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain IBB PF01749.20 OEU10361.1 - 1.2e-05 25.6 8.4 1.2e-05 25.6 8.4 3.2 3 1 0 3 3 3 1 Importin beta binding domain NodZ PF05830.11 OEU10361.1 - 0.0046 15.8 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) Spt20 PF12090.8 OEU10361.1 - 0.67 9.5 18.7 0.42 10.2 16.1 1.9 2 0 0 2 2 2 0 Spt20 family UPF0565 PF10561.9 OEU10361.1 - 1.6 7.9 8.3 0.72 9.0 5.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0565 Ndc1_Nup PF09531.10 OEU10361.1 - 9.8 4.7 15.4 18 3.9 15.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ank_4 PF13637.6 OEU10362.1 - 2e-06 28.2 0.0 0.065 13.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU10362.1 - 0.033 14.8 0.0 32 5.2 0.0 3.0 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 OEU10362.1 - 0.1 13.1 0.0 57 4.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Fis1_TPR_N PF14852.6 OEU10365.1 - 0.13 12.0 0.3 0.3 10.8 0.3 1.6 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat IMUP PF15761.5 OEU10365.1 - 2.2 9.0 6.3 4.3 8.1 6.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Fasciclin PF02469.22 OEU10366.1 - 6.5e-05 23.2 0.7 0.00014 22.1 0.2 1.8 2 0 0 2 2 2 1 Fasciclin domain MRI PF15325.6 OEU10366.1 - 0.026 15.6 0.9 0.026 15.6 0.9 2.0 1 1 1 2 2 2 0 Modulator of retrovirus infection PT PF04886.12 OEU10366.1 - 8.2 6.1 13.3 95 2.7 13.3 2.5 1 1 0 1 1 1 0 PT repeat HA PF03457.14 OEU10369.1 - 2e-45 153.0 2.6 1.5e-16 60.5 0.1 3.0 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU10369.1 - 0.022 14.8 0.6 7.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination Antirestrict PF03230.13 OEU10369.1 - 0.055 13.5 0.2 15 5.7 0.0 2.6 3 0 0 3 3 3 0 Antirestriction protein Atu4866 PF11512.8 OEU10369.1 - 0.12 12.8 0.5 12 6.3 0.0 3.3 3 1 1 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 BAF PF02961.14 OEU10372.1 - 0.042 14.3 0.1 0.8 10.2 0.0 2.4 2 1 1 3 3 3 0 Barrier to autointegration factor DUF4754 PF15946.5 OEU10372.1 - 0.079 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) Fungus-induced PF10917.8 OEU10374.1 - 0.013 15.8 1.0 0.018 15.4 1.0 1.3 1 0 0 1 1 1 0 Fungus-induced protein Anoctamin PF04547.12 OEU10374.1 - 0.14 10.9 0.0 0.17 10.7 0.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel hNIFK_binding PF12196.8 OEU10375.1 - 5.1 6.7 6.7 9.1 5.9 0.2 2.7 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK LRR_6 PF13516.6 OEU10376.1 - 0.0002 21.2 2.5 2.4 8.4 0.2 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 OEU10376.1 - 0.00094 19.4 4.2 6.5 7.7 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 OEU10376.1 - 0.011 16.1 10.2 0.19 12.2 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU10376.1 - 0.03 14.1 1.1 5 7.0 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 OEU10377.1 - 0.00051 20.4 11.3 0.0066 16.8 3.7 4.4 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU10377.1 - 0.016 15.2 2.1 0.016 15.2 2.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 OEU10377.1 - 0.32 10.8 2.7 9.5 6.1 2.1 3.3 2 2 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 OEU10377.1 - 8.3 7.4 7.3 17 6.5 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat Abhydrolase_3 PF07859.13 OEU10378.1 - 1.2e-07 31.8 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU10378.1 - 0.00023 21.9 0.0 0.00033 21.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OEU10378.1 - 0.0048 16.5 0.1 0.0081 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PMSR PF01625.21 OEU10378.1 - 0.039 14.1 3.2 0.082 13.1 3.2 1.4 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DUF4116 PF13475.6 OEU10379.1 - 1.9e-22 78.7 0.0 2.4e-11 43.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4116) SR-25 PF10500.9 OEU10381.1 - 0.037 13.6 11.9 0.057 13.0 11.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 OEU10381.1 - 1 9.7 16.7 0.088 13.1 3.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF755) SbsC_C PF18058.1 OEU10382.1 - 0.036 14.3 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 SbsC C-terminal domain MYO10_CC PF16735.5 OEU10382.1 - 0.36 11.0 1.4 0.81 9.8 0.2 2.1 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain Ribosomal_S30AE PF02482.19 OEU10383.1 - 0.26 12.1 3.5 0.26 12.1 0.8 2.3 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF285 PF03382.14 OEU10386.1 - 2.4e-22 79.0 1.4 5.3e-22 77.9 1.4 1.6 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 TLD PF07534.16 OEU10387.1 - 5.9e-06 26.5 7.4 0.00011 22.4 7.4 3.1 1 1 0 1 1 1 1 TLD zf-RING_2 PF13639.6 OEU10390.1 - 3.4e-05 24.1 6.4 0.00013 22.2 1.5 2.7 2 0 0 2 2 2 1 Ring finger domain Tetraspanin PF00335.20 OEU10390.1 - 0.00053 19.8 0.5 0.0012 18.6 0.5 1.5 1 1 0 1 1 1 1 Tetraspanin family FANCL_C PF11793.8 OEU10390.1 - 0.0022 18.1 0.6 0.0022 18.1 0.6 2.1 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_11 PF17123.5 OEU10390.1 - 0.0032 17.2 2.3 0.0085 15.8 2.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU10390.1 - 0.022 14.6 1.6 0.022 14.6 1.6 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U71 PF17474.2 OEU10390.1 - 0.1 12.6 0.2 0.1 12.6 0.2 2.4 3 0 0 3 3 2 0 Tegument protein UL11 homolog zf-ANAPC11 PF12861.7 OEU10390.1 - 0.12 12.4 2.2 0.26 11.4 0.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4713 PF15831.5 OEU10390.1 - 0.15 12.5 5.1 0.29 11.6 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) zf-RING_UBOX PF13445.6 OEU10390.1 - 0.3 11.1 3.9 0.17 11.9 0.8 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 OEU10390.1 - 0.31 11.3 8.0 0.2 11.9 2.2 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU10390.1 - 0.57 10.1 8.6 0.1 12.5 1.3 2.9 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 OEU10390.1 - 1.1 7.8 21.5 0.035 12.7 9.1 2.1 2 0 0 2 2 2 0 Macoilin family Zip PF02535.22 OEU10390.1 - 1.1 8.5 19.9 2.8 7.1 10.4 2.3 2 1 0 2 2 2 0 ZIP Zinc transporter TadF PF16964.5 OEU10390.1 - 3.3 7.4 9.0 0.074 12.8 0.9 2.0 2 0 0 2 2 2 0 Putative tight adherence pilin protein F CDC45 PF02724.14 OEU10390.1 - 4.2 5.6 13.1 0.073 11.4 3.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Comm PF15957.5 OEU10390.1 - 7.8 6.9 6.6 1.1 9.6 0.3 2.5 2 2 0 2 2 2 0 Commissureless HA PF03457.14 OEU10393.1 - 6.1e-77 253.9 6.1 3e-18 65.9 0.0 4.0 4 0 0 4 4 4 4 Helicase associated domain DUF5522 PF17653.1 OEU10393.1 - 8e-05 22.5 1.6 13 5.8 0.1 4.2 4 0 0 4 4 4 3 Family of unknown function (DUF5522) DUF3953 PF13129.6 OEU10393.1 - 0.0056 16.4 0.9 12 5.8 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3953) DUF4936 PF16290.5 OEU10393.1 - 0.035 14.8 1.6 8.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4936) VAPB_antitox PF02697.14 OEU10393.1 - 4.7 8.1 10.3 88 4.0 0.0 4.2 4 0 0 4 4 4 0 Putative antitoxin PCSK9_C1 PF18459.1 OEU10395.1 - 0.14 12.3 1.3 0.68 10.1 1.3 2.2 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain FAD_oxidored PF12831.7 OEU10396.1 - 6 6.1 9.6 3.3 6.9 0.0 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase PBP1_TM PF14812.6 OEU10396.1 - 6.7 7.2 12.8 2.6 8.5 8.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_3 PF13606.6 OEU10397.1 - 0.023 15.2 0.0 89 4.2 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat BTB PF00651.31 OEU10399.1 - 8.7e-14 51.7 0.0 8.6e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUF4800 PF16057.5 OEU10399.1 - 0.056 12.7 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) DUF2065 PF09838.9 OEU10399.1 - 0.098 12.7 1.2 15 5.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) VIR_N PF15912.5 OEU10400.1 - 0.015 14.9 3.4 0.034 13.7 3.4 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3292 PF11696.8 OEU10400.1 - 0.14 10.5 6.8 0.28 9.5 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Ndc1_Nup PF09531.10 OEU10400.1 - 8.7 4.9 16.6 16 4.0 16.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acetyltransf_10 PF13673.7 OEU10401.1 - 2.6e-06 27.4 0.4 0.0005 20.0 0.2 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU10401.1 - 1.3e-05 25.0 0.1 0.0044 16.9 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 OEU10401.1 - 0.00012 22.5 0.0 0.0092 16.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU10401.1 - 0.00072 19.8 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family RR_TM4-6 PF06459.12 OEU10401.1 - 0.042 13.7 2.1 0.1 12.4 2.1 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RXT2_N PF08595.11 OEU10401.1 - 1.1 9.3 9.9 11 6.0 6.3 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Haem_degrading PF03928.14 OEU10402.1 - 0.044 13.8 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Haem-degrading Orf78 PF06024.12 OEU10404.1 - 0.028 14.7 0.3 0.028 14.7 0.3 5.8 4 1 1 5 5 5 0 Orf78 (ac78) RskA PF10099.9 OEU10404.1 - 0.029 14.7 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Menin PF05053.13 OEU10404.1 - 0.38 9.0 25.8 0.048 12.0 14.0 2.3 2 0 0 2 2 2 0 Menin F-box PF00646.33 OEU10408.1 - 0.042 13.7 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 F-box domain Herpes_glycop PF01528.16 OEU10409.1 - 0.085 11.7 0.3 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF5623 PF18536.1 OEU10410.1 - 0.025 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) SAPS PF04499.15 OEU10412.1 - 0.0042 15.9 3.0 0.0064 15.3 3.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF629 PF04780.12 OEU10412.1 - 0.018 13.6 0.1 0.027 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Cwf_Cwc_15 PF04889.12 OEU10412.1 - 0.053 13.2 5.5 0.072 12.8 5.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AC_N PF16214.5 OEU10412.1 - 0.44 9.6 2.0 0.63 9.1 2.0 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Serglycin PF04360.12 OEU10414.1 - 0.24 11.3 2.2 5.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Serglycin UPF0137 PF03677.13 OEU10415.1 - 6e-05 22.9 2.0 6e-05 22.9 2.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0137) DUF4250 PF14056.6 OEU10415.1 - 0.72 9.9 5.0 0.53 10.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Amidohydro_2 PF04909.14 OEU10416.1 - 1.7e-22 80.6 0.0 2.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase THF_DHG_CYH PF00763.23 OEU10416.1 - 0.024 14.9 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF4521 PF15021.6 OEU10416.1 - 0.033 14.1 0.8 0.033 14.1 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) Plasmodium_Vir PF05795.11 OEU10417.1 - 0.79 9.1 8.5 0.82 9.0 8.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Membralin PF09746.9 OEU10417.1 - 1.5 7.8 5.6 1.6 7.7 5.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein TFIIA PF03153.13 OEU10417.1 - 1.8 8.5 31.7 2 8.3 31.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 OEU10417.1 - 3 4.8 15.2 3.1 4.8 15.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 OEU10417.1 - 3.3 6.6 11.0 3.6 6.5 11.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 OEU10417.1 - 9.8 6.3 8.1 15 5.7 8.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal 2OG-FeII_Oxy_3 PF13640.6 OEU10419.1 - 3.5e-06 27.8 0.1 9e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 OEU10420.1 - 7.6e-06 26.4 0.0 0.042 14.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU10420.1 - 0.00039 20.7 0.1 31 5.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OEU10420.1 - 0.0007 20.1 0.4 0.078 13.6 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) zf-CCHC_5 PF14787.6 OEU10425.1 - 0.0031 17.2 1.0 0.0031 17.2 1.0 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OEU10425.1 - 0.074 13.2 1.2 0.21 11.7 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle PNPase_C PF12111.8 OEU10425.1 - 0.2 11.1 0.8 0.73 9.3 0.8 2.0 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal DZR PF12773.7 OEU10425.1 - 5.1 7.2 7.3 0.95 9.5 1.8 2.2 2 0 0 2 2 2 0 Double zinc ribbon Fasciclin PF02469.22 OEU10427.1 - 1.2e-10 41.7 0.7 8.4e-05 22.8 0.1 2.3 1 1 1 2 2 2 2 Fasciclin domain RAP1 PF07218.11 OEU10428.1 - 0.00046 18.6 4.4 0.00047 18.6 4.4 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Ion_trans PF00520.31 OEU10428.1 - 0.019 14.2 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Ion transport protein DUF4366 PF14283.6 OEU10428.1 - 0.58 10.2 10.0 0.064 13.3 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Herpes_capsid PF06112.11 OEU10428.1 - 1 9.4 18.0 0.49 10.4 13.4 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DAG_kinase_N PF14513.6 OEU10428.1 - 1.8 8.8 11.7 0.87 9.8 0.8 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Folliculin PF11704.8 OEU10428.1 - 2.1 8.2 6.8 12 5.7 0.2 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport HSD3 PF15244.6 OEU10428.1 - 2.4 7.6 15.5 0.58 9.6 9.8 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 ORC_WH_C PF18137.1 OEU10428.1 - 5 7.2 8.3 0.93 9.6 2.1 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Kei1 PF08552.11 OEU10428.1 - 5.2 6.9 14.2 0.16 11.8 1.7 2.1 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 SPX PF03105.19 OEU10428.1 - 5.4 6.8 16.4 8.5 6.2 16.4 1.3 1 1 0 1 1 1 0 SPX domain BAF1_ABF1 PF04684.13 OEU10428.1 - 7.2 5.5 26.8 0.74 8.8 10.4 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PPL5 PF18168.1 OEU10428.1 - 7.4 5.8 11.6 1.6 7.9 2.5 2.1 2 0 0 2 2 2 0 Prim-pol family 5 SPATIAL PF15256.6 OEU10428.1 - 7.5 6.8 9.8 0.51 10.6 0.4 2.4 2 1 0 2 2 2 0 SPATIAL zf-MYND PF01753.18 OEU10432.1 - 0.00039 20.5 3.3 0.00072 19.6 3.3 1.4 1 0 0 1 1 1 1 MYND finger FtsH_ext PF06480.15 OEU10433.1 - 2.8e-07 30.9 5.6 5.5e-06 26.7 4.5 2.4 1 1 0 1 1 1 1 FtsH Extracellular Imm42 PF15593.6 OEU10434.1 - 0.035 14.6 0.1 0.095 13.2 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 42 GTA_holin_3TM PF11351.8 OEU10434.1 - 0.15 12.6 0.5 1.6 9.3 0.1 2.2 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release ParB PF08775.10 OEU10434.1 - 2.1 8.8 6.5 0.43 11.1 1.5 2.0 2 0 0 2 2 2 0 ParB family Ribosomal_60s PF00428.19 OEU10434.1 - 9.6 6.9 10.7 1.1 9.9 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF188 PF02639.14 OEU10435.1 - 0.073 12.7 0.5 0.092 12.4 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 zf-MYND PF01753.18 OEU10436.1 - 5.7e-08 32.7 9.6 5.7e-08 32.7 9.6 2.0 2 0 0 2 2 2 1 MYND finger POLO_box PF00659.18 OEU10436.1 - 0.083 13.1 0.6 4.6 7.5 0.2 2.5 2 1 0 2 2 2 0 POLO box duplicated region BCAS2 PF05700.11 OEU10437.1 - 2.2e-06 27.5 0.1 4.7e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) F-box-like PF12937.7 OEU10437.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU10437.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain O-antigen_lig PF13425.6 OEU10437.1 - 2.7 6.7 4.5 3.7 6.2 4.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SH3-WW_linker PF16618.5 OEU10438.1 - 1.7 9.1 18.1 2.1 8.8 18.1 1.1 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 AF-4 PF05110.13 OEU10438.1 - 1.9 6.5 20.1 4.6 5.2 19.1 1.8 1 1 0 1 1 1 0 AF-4 proto-oncoprotein SID-1_RNA_chan PF13965.6 OEU10438.1 - 3.3 6.0 4.3 4 5.7 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 OEU10438.1 - 4 6.2 5.5 4.4 6.1 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein LssY_C PF14067.6 OEU10439.1 - 0.0055 16.3 0.1 0.0091 15.6 0.1 1.4 1 0 0 1 1 1 1 LssY C-terminus DUF4667 PF15700.5 OEU10440.1 - 0.014 15.5 7.8 0.049 13.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) PA-IIL PF07472.11 OEU10440.1 - 0.25 11.6 1.1 1 9.7 0.1 2.2 2 1 1 3 3 3 0 Fucose-binding lectin II (PA-IIL) Lipase_GDSL_2 PF13472.6 OEU10441.1 - 0.0082 16.6 0.0 0.015 15.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2613 PF11021.8 OEU10442.1 - 0.12 12.5 1.7 0.3 11.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Med3 PF11593.8 OEU10442.1 - 1.7 7.7 18.3 3.1 6.9 18.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Bac_rhodopsin PF01036.18 OEU10445.1 - 7.5e-24 84.5 10.8 9.3e-24 84.2 10.8 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein COX7B PF05392.11 OEU10445.1 - 0.075 12.7 0.2 0.075 12.7 0.2 2.4 2 1 1 3 3 3 0 Cytochrome C oxidase chain VIIB TctB PF07331.11 OEU10445.1 - 4.7 7.5 12.6 0.72 10.1 1.1 2.8 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Pkinase PF00069.25 OEU10446.1 - 4.6e-26 91.8 5.8 2.7e-25 89.2 0.0 4.3 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10446.1 - 1.3e-14 54.2 10.4 4e-13 49.2 1.0 4.5 4 1 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 OEU10446.1 - 0.0011 18.3 0.0 0.0031 16.9 0.0 1.9 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU10446.1 - 0.0021 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family MRP-S32 PF10210.9 OEU10447.1 - 0.0051 17.3 1.0 0.011 16.3 0.9 1.6 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Ald_Xan_dh_C2 PF02738.18 OEU10448.1 - 0.054 11.9 0.1 0.065 11.7 0.1 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Dodecin PF07311.12 OEU10448.1 - 0.056 13.7 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Dodecin PEP-utilisers_N PF05524.13 OEU10448.1 - 0.12 12.5 0.7 0.2 11.8 0.1 1.8 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DNA_pol_A_exo1 PF01612.20 OEU10449.1 - 8.6e-09 35.3 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zinc_ribbon_4 PF13717.6 OEU10450.1 - 0.0075 16.2 1.1 4.6 7.2 0.2 2.8 2 0 0 2 2 2 2 zinc-ribbon domain K_channel_TID PF07941.11 OEU10450.1 - 1 9.8 7.7 0.22 12.0 0.8 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HA2 PF04408.23 OEU10450.1 - 9.5 6.6 6.4 29 5.0 0.0 2.8 2 1 1 3 3 3 0 Helicase associated domain (HA2) Yae1_N PF09811.9 OEU10454.1 - 0.00053 19.6 40.7 3.5 7.4 2.5 11.6 10 3 1 11 11 11 8 Essential protein Yae1, N terminal Yae1_N PF09811.9 OEU10455.1 - 0.002 17.8 2.4 0.002 17.8 2.4 6.1 3 2 3 6 6 6 2 Essential protein Yae1, N terminal DUF285 PF03382.14 OEU10457.1 - 3.7e-44 149.3 27.1 6.7e-29 100.1 13.2 2.4 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 BssS PF13991.6 OEU10457.1 - 0.065 13.3 2.3 15 5.8 0.1 3.8 2 2 1 3 3 3 0 BssS protein family SDA1 PF05285.12 OEU10458.1 - 5 6.4 8.7 5.4 6.3 8.7 1.1 1 0 0 1 1 1 0 SDA1 Menin PF05053.13 OEU10459.1 - 0.091 11.1 7.2 0.12 10.8 7.2 1.4 1 0 0 1 1 1 0 Menin FtsH_ext PF06480.15 OEU10459.1 - 0.67 10.3 5.0 2.2 8.7 5.0 2.0 1 1 0 1 1 1 0 FtsH Extracellular DDE_Tnp_1_7 PF13843.6 OEU10460.1 - 0.0032 16.8 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 TerC PF03741.16 OEU10461.1 - 0.11 12.2 2.3 7 6.3 0.0 2.6 3 0 0 3 3 3 0 Integral membrane protein TerC family CPSF100_C PF13299.6 OEU10461.1 - 0.73 10.0 4.3 1.3 9.2 0.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BTB_2 PF02214.22 OEU10464.1 - 6.8e-06 26.4 0.0 1.7e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 OEU10466.1 - 1.9e-25 89.7 0.0 2.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10466.1 - 2.9e-10 39.9 0.0 1.4e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU10466.1 - 0.00025 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU10466.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like STPPase_N PF16891.5 OEU10466.1 - 0.27 11.7 1.3 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain Glyco_transf_6 PF03414.13 OEU10468.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF285 PF03382.14 OEU10469.1 - 8.8e-111 364.4 44.6 1.9e-38 130.9 8.5 3.4 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 TGase_elicitor PF16683.5 OEU10469.1 - 0.0013 17.6 11.8 0.12 11.2 0.3 4.5 1 1 4 5 5 5 3 Transglutaminase elicitor PucR PF07905.11 OEU10469.1 - 0.045 14.0 0.0 12 6.2 0.0 3.6 4 0 0 4 4 4 0 Purine catabolism regulatory protein-like family SAPI PF16560.5 OEU10469.1 - 0.053 13.1 1.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Putative mobile pathogenicity island BssS PF13991.6 OEU10469.1 - 0.45 10.6 5.6 10 6.3 0.0 5.3 6 2 2 8 8 8 0 BssS protein family ASFV_J13L PF05568.11 OEU10470.1 - 0.0019 18.0 0.1 0.0044 16.8 0.1 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF3494 PF11999.8 OEU10472.1 - 2.9e-54 183.9 15.6 3.2e-54 183.7 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Arg_decarb_HB PF17810.1 OEU10472.1 - 0.14 12.4 0.0 0.58 10.4 0.0 1.8 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain DNA_pol3_beta PF00712.19 OEU10472.1 - 0.14 12.3 0.7 5.1 7.2 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain MAM PF00629.23 OEU10473.1 - 7.3e-05 22.7 0.0 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu DUF4748 PF15932.5 OEU10473.1 - 0.09 12.5 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) CobW_C PF07683.14 OEU10474.1 - 3.1e-13 49.4 0.0 3.7e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF285 PF03382.14 OEU10475.1 - 1.1e-64 215.7 25.7 2.2e-36 124.3 8.8 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 TGase_elicitor PF16683.5 OEU10475.1 - 0.011 14.6 4.6 0.35 9.6 0.3 2.9 1 1 2 3 3 3 0 Transglutaminase elicitor BssS PF13991.6 OEU10475.1 - 0.25 11.5 4.5 85 3.3 0.0 4.4 3 1 3 6 6 6 0 BssS protein family PRKCSH-like PF12999.7 OEU10476.1 - 1.7e-08 34.5 17.6 2.5e-08 33.9 10.0 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like DUF3185 PF11381.8 OEU10476.1 - 0.021 14.8 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Ldl_recept_a PF00057.18 OEU10476.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.1 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A F_actin_cap_B PF01115.17 OEU10477.1 - 3.9e-17 62.7 13.9 5.7e-15 55.6 13.9 3.4 1 1 0 1 1 1 1 F-actin capping protein, beta subunit EF-hand_7 PF13499.6 OEU10478.1 - 9.4e-07 29.2 2.7 3.9e-06 27.2 1.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU10478.1 - 1.9e-05 23.9 0.2 0.0031 17.0 0.0 4.8 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 OEU10478.1 - 0.081 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.6 OEU10478.1 - 0.086 12.8 0.0 0.086 12.8 0.0 4.4 5 0 0 5 5 5 0 EF-hand domain EF-hand_8 PF13833.6 OEU10478.1 - 0.93 9.4 3.8 22 5.0 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair Glyco_transf_10 PF00852.19 OEU10479.1 - 5.4e-08 32.8 0.1 1.6e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term EspA PF03433.13 OEU10479.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.1 1 0 0 1 1 1 0 EspA-like secreted protein PhyH PF05721.13 OEU10480.1 - 0.0032 17.8 0.0 0.0043 17.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Bacteriocin_IIc PF10439.9 OEU10481.1 - 0.00029 20.9 2.2 0.00044 20.3 2.2 1.3 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 OEU10481.1 - 0.0019 18.4 0.5 0.003 17.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 OEU10481.1 - 0.0024 17.6 8.2 0.0034 17.1 8.2 1.2 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF456 PF04306.13 OEU10481.1 - 0.0027 18.0 0.1 0.0038 17.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 OEU10481.1 - 0.009 16.0 8.5 0.013 15.4 8.5 1.3 1 0 0 1 1 1 1 Glycine zipper Glt_symporter PF03616.14 OEU10481.1 - 0.095 11.4 3.7 1.1 7.9 3.7 2.0 1 1 0 1 1 1 0 Sodium/glutamate symporter TFIIA PF03153.13 OEU10482.1 - 0.003 17.6 21.8 0.0036 17.4 21.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 OEU10482.1 - 0.051 12.3 18.1 0.055 12.1 18.1 1.0 1 0 0 1 1 1 0 Hamartin protein LAP1C PF05609.12 OEU10482.1 - 0.075 12.1 22.9 0.086 11.9 22.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PNISR PF15996.5 OEU10482.1 - 0.38 11.0 22.4 0.55 10.5 22.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Cyto_heme_lyase PF01265.17 OEU10482.1 - 0.57 9.7 16.6 0.79 9.3 16.6 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase PI3K_1B_p101 PF10486.9 OEU10482.1 - 1.1 6.9 16.8 1.4 6.6 16.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 OEU10482.1 - 1.3 6.0 21.1 1.5 5.9 21.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 OEU10482.1 - 2.3 8.2 16.8 3 7.9 16.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPP4R2 PF09184.11 OEU10482.1 - 2.5 7.6 23.0 3.3 7.2 23.0 1.3 1 0 0 1 1 1 0 PPP4R2 DUF1387 PF07139.11 OEU10482.1 - 2.9 7.5 24.0 4.3 7.0 24.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hid1 PF12722.7 OEU10482.1 - 3.1 5.8 24.5 3.9 5.5 24.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pneumo_att_G PF05539.11 OEU10482.1 - 4.6 6.7 23.2 5.8 6.4 23.2 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Macoilin PF09726.9 OEU10482.1 - 4.8 5.6 20.9 6.7 5.1 20.9 1.3 1 0 0 1 1 1 0 Macoilin family IRF PF00605.17 OEU10483.1 - 0.0053 17.0 1.7 0.0063 16.8 1.7 1.2 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor CCDC117 PF15810.5 OEU10483.1 - 0.009 16.3 0.7 0.012 15.9 0.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 4HBT PF03061.22 OEU10484.1 - 6.6e-17 61.6 0.1 9.9e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PS-DH PF14765.6 OEU10484.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase Pmp3 PF01679.17 OEU10485.1 - 4.6 7.5 7.6 5.8 7.2 0.5 2.2 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Cupin_8 PF13621.6 OEU10486.1 - 2.8e-17 63.3 0.2 5.2e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU10486.1 - 0.00092 18.8 0.0 0.0045 16.5 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 OEU10486.1 - 0.0011 18.6 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 OEU10486.1 - 0.0032 17.9 0.2 0.011 16.2 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Ank_2 PF12796.7 OEU10487.1 - 0.00058 20.4 0.0 0.27 11.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU10487.1 - 0.082 13.5 0.1 37 5.1 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ofd1_CTDD PF10637.9 OEU10489.1 - 2.1e-51 174.8 1.3 2.8e-51 174.3 1.3 1.1 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term LRR_8 PF13855.6 OEU10491.1 - 1.1e-34 118.0 45.7 1.6e-07 30.9 0.8 8.7 3 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 OEU10491.1 - 2.2e-25 88.3 53.7 6.4e-05 23.2 1.5 10.6 5 3 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU10491.1 - 1.6e-16 58.3 42.9 1.4 9.7 0.3 16.6 17 0 0 17 17 17 5 Leucine Rich Repeat LRR_6 PF13516.6 OEU10491.1 - 2.7e-07 30.1 27.8 6.3 7.1 0.2 11.5 12 0 0 12 12 12 3 Leucine Rich repeat Ephrin_rec_like PF07699.13 OEU10491.1 - 0.0046 16.7 4.2 0.009 15.8 4.2 1.4 1 0 0 1 1 1 1 Putative ephrin-receptor like LRRNT_2 PF08263.12 OEU10491.1 - 0.0054 17.0 0.5 0.023 15.0 0.1 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain GAT PF03127.14 OEU10492.1 - 0.0034 17.6 0.0 0.0077 16.5 0.0 1.6 1 0 0 1 1 1 1 GAT domain DDE_Tnp_1_7 PF13843.6 OEU10493.1 - 2.9e-17 63.0 0.5 9.8e-17 61.3 0.5 1.8 1 1 0 1 1 1 1 Transposase IS4 PBP1_TM PF14812.6 OEU10494.1 - 0.31 11.4 0.0 0.31 11.4 0.0 5.2 4 1 1 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABM PF03992.16 OEU10495.1 - 0.29 11.3 2.2 3.2 7.9 0.1 2.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Silic_transp PF03842.13 OEU10496.1 - 9.6e-235 779.7 8.3 1.1e-234 779.4 8.3 1.0 1 0 0 1 1 1 1 Silicon transporter MauE PF07291.11 OEU10496.1 - 2.7 7.7 8.9 0.77 9.5 0.4 3.2 2 1 2 4 4 4 0 Methylamine utilisation protein MauE Pex2_Pex12 PF04757.14 OEU10497.1 - 0.093 12.3 1.6 1.2 8.6 0.0 3.0 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF3446 PF11928.8 OEU10497.1 - 5.9 7.3 21.9 0.21 11.9 3.8 3.9 4 0 0 4 4 4 0 Early growth response N-terminal domain SPATA48 PF15073.6 OEU10498.1 - 1.5 9.1 4.5 25 5.2 0.1 3.0 3 0 0 3 3 3 0 Spermatogenesis-associated protein 48 LRR_11 PF18831.1 OEU10499.1 - 0.015 14.9 0.4 0.084 12.4 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat Lipoprotein_7 PF01540.16 OEU10499.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Methyltransf_32 PF13679.6 OEU10500.1 - 4.2e-10 39.8 0.0 4.2e-10 39.8 0.0 3.5 5 1 0 5 5 5 1 Methyltransferase domain ANAPC_CDC26 PF10471.9 OEU10500.1 - 0.023 15.5 3.5 0.023 15.5 3.5 4.2 5 2 0 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 SUIM_assoc PF16619.5 OEU10500.1 - 1.4 9.0 9.1 0.072 13.2 1.4 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HSP20 PF00011.21 OEU10501.1 - 1.9e-06 27.9 0.0 0.00022 21.3 0.0 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family SR-25 PF10500.9 OEU10501.1 - 0.00061 19.5 6.1 0.00072 19.2 6.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FTZ PF03867.14 OEU10501.1 - 0.046 13.3 4.8 0.058 12.9 4.8 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF3537 PF12056.8 OEU10501.1 - 0.11 11.3 3.1 0.14 10.9 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) ArsA_HSP20 PF17886.1 OEU10501.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA PRP38_assoc PF12871.7 OEU10501.1 - 0.48 11.0 12.9 0.68 10.6 12.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term OrfA PF17495.2 OEU10502.1 - 0.092 12.9 0.5 0.25 11.5 0.5 1.7 1 1 0 1 1 1 0 Vpr-like OrfA zf-RING_UBOX PF13445.6 OEU10502.1 - 0.76 9.9 5.9 1.8 8.7 5.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OEU10502.1 - 0.88 10.0 5.6 1.6 9.1 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain Thioredoxin_8 PF13905.6 OEU10503.1 - 3.6e-25 88.1 0.0 5.9e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OEU10503.1 - 1.2e-06 28.4 0.1 1.9e-05 24.6 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU10503.1 - 0.0003 21.2 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 OEU10503.1 - 0.0039 16.9 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU10503.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 OEU10503.1 - 0.079 13.2 0.1 1 9.6 0.1 2.3 1 1 0 1 1 1 0 Glutaredoxin TraF PF13728.6 OEU10503.1 - 0.13 12.1 0.0 0.86 9.4 0.0 2.0 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OEU10503.1 - 0.19 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like MFS_2 PF13347.6 OEU10504.1 - 0.00048 18.8 3.0 0.0006 18.5 3.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Ost5 PF05251.12 OEU10504.1 - 0.017 15.4 5.0 0.035 14.4 5.0 1.6 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 PDH PF02153.17 OEU10504.1 - 0.032 13.2 0.1 0.041 12.9 0.1 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase SAP PF02037.27 OEU10505.1 - 1e-12 47.5 1.3 2.5e-05 23.9 0.2 2.5 2 0 0 2 2 2 2 SAP domain SpoU_sub_bind PF08032.12 OEU10505.1 - 0.078 13.3 0.5 0.85 9.9 0.1 2.6 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding MCM_OB PF17207.3 OEU10505.1 - 0.43 10.4 3.4 0.45 10.4 1.0 2.1 2 0 0 2 2 2 0 MCM OB domain LRR_4 PF12799.7 OEU10506.1 - 1.9e-15 56.7 32.5 6.2e-05 23.3 1.2 6.6 4 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU10506.1 - 1.9e-09 37.1 24.9 0.00096 18.9 1.0 5.8 4 2 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 OEU10506.1 - 2.2e-06 27.3 7.3 0.0021 17.6 0.3 3.6 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OEU10506.1 - 0.00053 20.2 32.9 2 9.2 0.0 9.4 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_2 PF07723.13 OEU10506.1 - 0.0016 19.0 1.7 0.48 11.2 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 OEU10506.1 - 0.41 10.8 13.5 2.9 8.2 0.2 6.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_3 PF07725.12 OEU10506.1 - 1 9.3 5.2 6.6 6.8 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat LETM1 PF07766.13 OEU10507.1 - 0.015 14.7 0.0 0.047 13.0 0.0 1.8 2 1 0 2 2 2 0 LETM1-like protein DUF4064 PF13273.6 OEU10507.1 - 0.024 14.9 0.6 0.024 14.9 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4383 PF14325.6 OEU10507.1 - 0.051 13.9 0.3 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) DUF3357 PF11837.8 OEU10507.1 - 0.15 12.5 0.0 2.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) TMEM132D_C PF15706.5 OEU10507.1 - 0.28 11.0 0.9 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Trypsin PF00089.26 OEU10508.1 - 4.6e-43 147.6 0.3 5.3e-43 147.4 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU10508.1 - 0.0077 17.1 0.1 0.019 15.9 0.0 1.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain CoaE PF01121.20 OEU10508.1 - 0.15 11.7 0.0 15 5.2 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase DIX PF00778.17 OEU10509.1 - 4.8e-07 29.5 0.0 7.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 DIX domain eIF-3_zeta PF05091.12 OEU10509.1 - 0.075 12.0 8.3 0.09 11.7 8.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 OEU10509.1 - 0.35 10.2 4.9 0.43 9.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3984 PF13136.6 OEU10509.1 - 0.41 10.0 20.9 0.77 9.1 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Connexin PF00029.19 OEU10509.1 - 1.6 8.4 4.2 2.3 7.9 4.2 1.2 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 OEU10509.1 - 2 6.2 7.1 2.5 5.9 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 OEU10509.1 - 5.5 6.7 7.7 97 2.6 9.6 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Spt5_N PF11942.8 OEU10509.1 - 5.9 7.9 15.2 3.5 8.7 0.2 2.6 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal FYDLN_acid PF09538.10 OEU10509.1 - 6 7.6 9.9 14 6.4 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1967 PF09269.11 OEU10510.1 - 0.036 14.0 0.2 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Choline_transpo PF04515.12 OEU10511.1 - 2.1e-66 224.4 36.9 2.1e-66 224.4 36.9 2.8 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF4190 PF13828.6 OEU10511.1 - 0.06 13.1 0.0 0.06 13.1 0.0 5.7 7 1 0 7 7 7 0 Domain of unknown function (DUF4190) NUC202 PF08166.12 OEU10511.1 - 0.06 13.4 1.7 0.17 11.9 1.7 1.7 1 0 0 1 1 1 0 NUC202 domain SseC PF04888.12 OEU10511.1 - 0.21 11.2 0.9 1.5 8.4 0.3 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family YWFCY PF14293.6 OEU10511.1 - 2.5 8.5 10.5 1.9 8.9 1.0 3.6 2 1 1 3 3 3 0 YWFCY protein Histone PF00125.24 OEU10514.1 - 1.9e-50 170.6 0.4 2.1e-50 170.4 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OEU10514.1 - 0.0011 19.0 0.2 0.0019 18.3 0.0 1.4 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU10514.1 - 0.0017 18.7 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OEU10514.1 - 0.03 14.6 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OEU10514.1 - 0.04 14.5 0.3 0.047 14.3 0.3 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 OEU10514.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-RING_2 PF13639.6 OEU10515.1 - 1.7e-05 25.0 18.0 0.00044 20.5 18.0 2.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU10515.1 - 0.00013 22.2 15.4 0.0003 21.0 15.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OEU10515.1 - 0.031 14.3 9.1 0.19 11.8 9.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PBP1_TM PF14812.6 OEU10515.1 - 0.59 10.5 3.9 6.1 7.3 1.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FANCL_C PF11793.8 OEU10515.1 - 1.5 9.0 13.2 31 4.8 13.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain F-box PF00646.33 OEU10517.1 - 0.00057 19.7 0.4 0.0015 18.4 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OEU10517.1 - 0.068 13.1 1.4 0.17 11.8 1.4 1.6 1 0 0 1 1 1 0 F-box-like FAD_binding_4 PF01565.23 OEU10518.1 - 1.7e-34 118.5 0.0 2.7e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OEU10518.1 - 1.1e-31 110.4 0.0 1.5e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain IRF-2BP1_2 PF11261.8 OEU10518.1 - 0.044 13.3 0.1 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger NAD_binding_4 PF07993.12 OEU10519.1 - 9.8e-37 126.5 0.0 7.5e-36 123.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein DegT_DnrJ_EryC1 PF01041.17 OEU10519.1 - 4.6e-19 68.9 0.1 2.3e-14 53.5 0.0 2.9 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Acyltransferase PF01553.21 OEU10519.1 - 8.7e-19 67.5 0.1 5.3e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Acyltransferase ACBP PF00887.19 OEU10519.1 - 3.5e-12 46.4 0.0 8.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Epimerase PF01370.21 OEU10519.1 - 5.5e-09 35.9 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU10519.1 - 1.9e-05 24.2 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OEU10519.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 OEU10519.1 - 0.1 11.7 0.4 0.42 9.7 0.4 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 OEU10519.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 KR domain LCM PF04072.14 OEU10520.1 - 1.6e-15 57.5 0.0 1.1e-14 54.8 0.0 2.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_7 PF13508.7 OEU10520.1 - 3.4e-10 40.2 0.0 9.2e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU10520.1 - 4.1e-09 36.7 0.0 7.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU10520.1 - 4.4e-08 33.1 0.0 8.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OEU10520.1 - 0.0099 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 OEU10520.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OEU10520.1 - 0.14 12.1 0.1 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Pkinase PF00069.25 OEU10521.1 - 1.2e-09 38.0 0.1 1.7e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10521.1 - 1.2e-08 34.6 0.0 1.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU10521.1 - 3.1e-07 29.9 0.0 5.4e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OEU10521.1 - 1.8e-05 24.4 0.5 5.7e-05 22.8 0.5 1.8 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OEU10521.1 - 2.1e-05 24.5 0.0 0.0017 18.3 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 OEU10521.1 - 0.00027 19.9 0.1 0.00035 19.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 OEU10521.1 - 0.00044 19.6 0.1 0.0006 19.2 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 OEU10521.1 - 0.0014 17.5 0.5 0.0031 16.3 0.4 1.6 1 1 0 1 1 1 1 Fungal protein kinase Sec1 PF00995.23 OEU10521.1 - 0.024 13.9 0.1 0.03 13.6 0.1 1.0 1 0 0 1 1 1 0 Sec1 family Homoserine_dh PF00742.19 OEU10523.1 - 8.1e-32 110.5 0.3 1.4e-31 109.7 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase ELFV_dehydrog PF00208.21 OEU10523.1 - 0.00059 19.6 0.5 0.0015 18.3 0.5 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PRK PF00485.18 OEU10524.1 - 1.1e-37 129.7 0.1 1.4e-37 129.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 OEU10524.1 - 4.6e-09 35.8 0.0 8.9e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 OEU10524.1 - 3.5e-07 30.8 0.0 6.8e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OEU10524.1 - 1.4e-05 25.6 0.0 2e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter Cytidylate_kin PF02224.18 OEU10524.1 - 0.00013 21.8 1.5 0.0026 17.5 0.1 2.1 1 1 0 2 2 2 1 Cytidylate kinase CoaE PF01121.20 OEU10524.1 - 0.00016 21.4 3.8 0.022 14.4 0.1 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_33 PF13671.6 OEU10524.1 - 0.00039 20.6 0.1 0.00061 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 OEU10524.1 - 0.0013 18.7 0.1 0.68 9.7 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase T2SSE PF00437.20 OEU10524.1 - 0.0043 16.2 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein KAP_NTPase PF07693.14 OEU10524.1 - 0.016 14.4 0.0 0.022 14.0 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain TIP49 PF06068.13 OEU10524.1 - 0.017 14.3 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 OEU10524.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OEU10524.1 - 0.024 14.7 0.4 0.035 14.2 0.4 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 OEU10524.1 - 0.035 14.5 4.6 0.74 10.2 4.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OEU10524.1 - 0.066 13.7 4.2 3.4 8.1 3.5 2.2 1 1 1 2 2 2 0 AAA domain PDGLE PF13190.6 OEU10524.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain Nt_Gln_amidase PF09764.9 OEU10525.1 - 2.3e-46 157.7 8.2 3.4e-46 157.2 8.2 1.5 1 1 0 1 1 1 1 N-terminal glutamine amidase Hira PF07569.11 OEU10525.1 - 0.0024 17.6 2.4 0.084 12.6 0.3 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split Mucin PF01456.17 OEU10525.1 - 0.009 16.0 16.2 0.079 12.9 3.6 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein Dicty_REP PF05086.12 OEU10525.1 - 0.059 11.4 20.2 0.14 10.1 9.6 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein NPR3 PF03666.13 OEU10525.1 - 0.06 12.1 0.1 0.06 12.1 0.1 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4569 PF15133.6 OEU10525.1 - 0.15 11.8 9.1 0.31 10.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) DUF719 PF05334.13 OEU10525.1 - 1.3 9.2 12.8 2.2 8.4 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF719) SR-25 PF10500.9 OEU10525.1 - 1.7 8.2 15.6 0.17 11.5 8.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SSP160 PF06933.11 OEU10525.1 - 1.9 6.6 9.8 3.9 5.6 4.9 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DGF-1_C PF11040.8 OEU10525.1 - 2 8.5 5.2 6.4 6.9 0.1 2.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF3439 PF11921.8 OEU10525.1 - 2.6 8.0 13.5 4.3 7.3 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) RR_TM4-6 PF06459.12 OEU10525.1 - 3.9 7.2 12.9 6.3 6.5 2.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCDC117 PF15810.5 OEU10525.1 - 3.9 7.8 7.2 0.42 10.9 2.1 1.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 117 Peptidase_S49_N PF08496.10 OEU10525.1 - 7.1 6.7 10.4 1.4 9.0 4.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hydin_ADK PF17213.3 OEU10525.1 - 8.3 6.6 8.8 9 6.5 2.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SIT PF15330.6 OEU10527.1 - 0.0064 16.9 0.0 0.0089 16.5 0.0 1.2 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT ATG11 PF10377.9 OEU10528.1 - 2.6e-18 66.3 0.0 5.5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.12 OEU10528.1 - 3.5e-06 26.4 4.9 3.5e-06 26.4 4.9 2.7 2 1 0 2 2 2 1 Autophagy protein Apg17 DUF2009 PF09418.10 OEU10528.1 - 0.0034 16.5 1.8 0.0047 16.1 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) SF-assemblin PF06705.11 OEU10528.1 - 1.2 8.4 9.6 0.71 9.2 0.1 2.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Fib_alpha PF08702.10 OEU10528.1 - 4.7 7.4 10.6 0.98 9.6 2.3 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TRAM_LAG1_CLN8 PF03798.16 OEU10529.1 - 2.5e-10 40.4 21.1 5.1e-10 39.4 21.2 1.5 1 1 1 2 2 2 1 TLC domain WD40 PF00400.32 OEU10530.1 - 8.1e-10 39.1 1.6 5.7e-06 27.0 0.1 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU10530.1 - 0.0011 19.3 0.1 0.24 11.7 0.0 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU10530.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Tubulin PF00091.25 OEU10532.1 - 3.2e-69 233.1 0.0 7.7e-69 231.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OEU10532.1 - 6.2e-42 142.7 0.0 1.9e-41 141.1 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OEU10532.1 - 1.5e-05 25.3 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OEU10532.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like PolyA_pol PF01743.20 OEU10534.1 - 1.9e-24 86.5 0.7 1.6e-20 73.8 0.0 3.5 4 0 0 4 4 4 2 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OEU10534.1 - 3.1e-05 23.7 0.0 8.5e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Secretin_N_2 PF07655.13 OEU10534.1 - 4.2 8.0 14.9 3.7 8.2 4.0 3.3 3 0 0 3 3 3 0 Secretin N-terminal domain Baculo_LEF-3 PF05847.11 OEU10535.1 - 0.0044 16.3 0.2 0.0049 16.1 0.2 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus late expression factor 3 (LEF-3) TMEM65 PF10507.9 OEU10536.1 - 2.1e-34 117.7 5.0 2.1e-34 117.7 5.0 1.8 2 0 0 2 2 2 1 Transmembrane protein 65 PT-VENN PF04829.13 OEU10536.1 - 0.035 14.2 1.5 2.8 8.1 0.0 3.0 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Sigma54_AID PF00309.20 OEU10536.1 - 0.16 11.8 1.0 0.34 10.8 1.0 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) DDE_Tnp_1_7 PF13843.6 OEU10537.1 - 5.6e-12 45.6 0.0 1.9e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Transposase IS4 GST_N PF02798.20 OEU10538.1 - 1.4e-06 28.5 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU10538.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU10538.1 - 0.082 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RE_AccI PF09545.10 OEU10538.1 - 0.097 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease ShK PF01549.24 OEU10539.1 - 0.00032 21.2 10.5 0.00061 20.3 10.5 1.5 1 0 0 1 1 1 1 ShK domain-like TPR_12 PF13424.6 OEU10540.1 - 0.00071 19.8 0.0 0.62 10.4 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 OEU10541.1 - 9.5e-06 25.8 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU10541.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU10541.1 - 0.018 15.5 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain C2 PF00168.30 OEU10541.1 - 0.11 12.8 0.0 0.81 10.0 0.0 2.0 2 0 0 2 2 2 0 C2 domain Acetyltransf_3 PF13302.7 OEU10541.1 - 0.11 13.2 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 OEU10542.1 - 3e-44 150.9 1.6 1.3e-43 148.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU10542.1 - 1.1e-15 58.0 0.7 1.9e-13 50.7 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU10542.1 - 6.4e-09 36.0 0.2 8.1e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 OEU10542.1 - 0.0022 18.2 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1604 PF07713.13 OEU10542.1 - 0.0066 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) DUF4860 PF16152.5 OEU10542.1 - 0.087 12.7 0.1 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4860) AAA_22 PF13401.6 OEU10542.1 - 1 9.6 3.5 2.3 8.5 2.0 2.3 2 1 0 2 2 2 0 AAA domain DnaJ PF00226.31 OEU10544.1 - 3.7e-06 27.0 0.5 1e-05 25.5 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.20 OEU10545.1 - 1.2e-16 59.5 25.0 6.4e-07 28.9 0.4 5.8 7 0 0 7 7 7 4 MORN repeat Tudor_2 PF18104.1 OEU10545.1 - 0.056 13.1 8.7 1 9.1 0.0 4.7 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain LSM PF01423.22 OEU10549.1 - 2.1e-09 37.0 0.1 2.7e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain Skp1 PF01466.19 OEU10550.1 - 1.2e-13 50.9 0.5 2.4e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OEU10550.1 - 0.013 15.6 1.4 0.14 12.4 1.4 2.3 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain Cwf_Cwc_15 PF04889.12 OEU10550.1 - 2 8.1 6.7 3 7.5 6.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TnpW PF14202.6 OEU10551.1 - 0.018 14.8 1.8 0.03 14.1 0.2 2.1 2 0 0 2 2 2 0 Transposon-encoded protein TnpW Spectrin PF00435.21 OEU10551.1 - 0.1 13.1 0.4 0.15 12.5 0.4 1.3 1 0 0 1 1 1 0 Spectrin repeat TPR_14 PF13428.6 OEU10552.1 - 1.6e-07 31.5 4.0 0.022 15.5 0.2 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10552.1 - 2.5e-07 30.3 10.3 0.00045 20.1 0.8 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU10552.1 - 8.8e-07 28.5 0.7 0.23 11.2 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 OEU10552.1 - 2.4e-06 27.9 1.8 0.27 11.8 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU10552.1 - 4.7e-06 27.1 2.9 0.0075 16.9 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU10552.1 - 1.1e-05 25.5 0.2 0.69 10.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10552.1 - 7e-05 22.5 1.2 0.0064 16.3 0.4 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10552.1 - 0.0022 18.5 0.2 0.15 12.7 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10552.1 - 0.0051 16.7 0.6 0.096 12.8 0.1 3.2 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU10552.1 - 0.1 12.7 2.1 4.8 7.4 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Phytochelatin PF05023.14 OEU10552.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Phytochelatin synthase EF-G-binding_N PF07299.11 OEU10552.1 - 0.18 12.3 0.3 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal TPR_8 PF13181.6 OEU10552.1 - 0.28 11.5 4.4 10 6.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU10552.1 - 2.5 8.5 10.0 0.29 11.5 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM132D_N PF15705.5 OEU10553.1 - 0.12 12.2 0.9 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Thr_dehydrat_C PF00585.18 OEU10553.1 - 0.14 11.9 0.1 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase DUF4537 PF15057.6 OEU10555.1 - 0.0002 21.4 0.1 0.00025 21.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 OEU10555.1 - 0.00026 20.7 1.0 0.00048 19.9 1.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 OEU10555.1 - 0.0017 18.0 2.8 0.0017 18.0 2.8 1.7 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 OEU10555.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain SMN PF06003.12 OEU10555.1 - 0.19 11.0 0.4 0.21 10.8 0.4 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF676 PF05057.14 OEU10556.1 - 0.0008 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 OEU10556.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_6 PF12697.7 OEU10556.1 - 0.17 12.5 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4589 PF15252.6 OEU10556.1 - 0.4 10.6 7.3 2.6 8.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) IMUP PF15761.5 OEU10556.1 - 1.6 9.5 13.8 1.4 9.6 4.4 2.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein DUF3446 PF11928.8 OEU10556.1 - 2.7 8.3 18.8 0.84 10.0 3.9 3.6 3 0 0 3 3 3 0 Early growth response N-terminal domain AAA_2 PF07724.14 OEU10557.1 - 5.7e-54 182.8 0.2 6.2e-53 179.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OEU10557.1 - 7.5e-35 119.0 2.6 2.5e-34 117.3 0.1 2.8 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OEU10557.1 - 6e-26 90.3 0.1 2.7e-25 88.2 0.1 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OEU10557.1 - 6.7e-22 78.3 0.0 1.3e-11 45.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU10557.1 - 3.1e-16 59.6 0.0 3.2e-11 43.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU10557.1 - 1e-09 39.0 0.5 0.00091 19.6 0.1 4.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OEU10557.1 - 1.3e-07 32.0 2.6 0.0076 16.5 0.0 4.7 3 2 0 4 4 3 2 AAA domain Sigma54_activat PF00158.26 OEU10557.1 - 2e-07 30.9 0.0 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 OEU10557.1 - 6e-07 29.1 0.2 0.025 14.0 0.1 4.4 3 1 0 3 3 3 1 Bacterial TniB protein IstB_IS21 PF01695.17 OEU10557.1 - 4e-06 26.7 0.0 0.081 12.6 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OEU10557.1 - 4.4e-06 27.3 0.0 0.022 15.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OEU10557.1 - 2.4e-05 23.8 0.0 1.4 8.2 0.0 3.7 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI Clp_N PF02861.20 OEU10557.1 - 2.9e-05 24.1 0.1 0.0033 17.5 0.0 3.0 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component Roc PF08477.13 OEU10557.1 - 0.00018 21.7 0.0 0.26 11.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OEU10557.1 - 0.00019 21.0 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 OEU10557.1 - 0.0002 21.3 0.8 3.8 7.3 0.0 4.2 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 OEU10557.1 - 0.00074 19.3 4.5 2.4 7.9 0.7 4.4 5 1 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OEU10557.1 - 0.00087 19.3 0.0 1.3 9.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OEU10557.1 - 0.0012 18.4 0.0 0.023 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OEU10557.1 - 0.0036 17.2 0.0 0.58 10.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 OEU10557.1 - 0.0048 16.2 0.0 1.3 8.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 OEU10557.1 - 0.0058 16.4 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OEU10557.1 - 0.0071 16.9 0.1 0.3 11.6 0.0 2.9 3 0 0 3 3 2 1 ABC transporter RNA_helicase PF00910.22 OEU10557.1 - 0.011 16.1 0.0 2.3 8.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OEU10557.1 - 0.012 15.6 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 OEU10557.1 - 0.015 15.3 0.0 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 OEU10557.1 - 0.032 14.0 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OEU10557.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 OEU10557.1 - 0.086 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 OEU10557.1 - 0.094 13.0 0.0 8.8 6.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 OEU10557.1 - 0.13 12.6 0.3 4.6 7.6 0.3 3.1 2 1 0 2 2 2 0 AAA domain FlaC_arch PF05377.11 OEU10557.1 - 2.6 8.5 4.6 5 7.6 1.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_L21p PF00829.21 OEU10558.1 - 7.2e-22 77.6 0.1 1.4e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Tub_N PF16322.5 OEU10558.1 - 0.14 12.6 5.2 0.13 12.7 2.5 2.0 2 0 0 2 2 2 0 Tubby N-terminal CNDH2_C PF16858.5 OEU10558.1 - 3.7 7.3 15.6 1.3 8.9 7.9 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 OEU10558.1 - 4 5.6 15.5 0.14 10.4 9.4 1.6 2 0 0 2 2 2 0 CDC45-like protein HSP33 PF01430.19 OEU10560.1 - 5.4e-61 206.4 0.0 6.4e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein DUF2811 PF10929.8 OEU10560.1 - 0.15 12.3 0.1 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) TatD_DNase PF01026.21 OEU10561.1 - 6.4e-42 143.7 0.0 7.3e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Colicin_im PF03857.13 OEU10562.1 - 0.012 15.6 1.0 0.061 13.3 1.0 2.2 1 0 0 1 1 1 0 Colicin immunity protein FixQ PF05545.11 OEU10562.1 - 0.038 14.0 1.0 0.038 14.0 1.0 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ TRI9 PF08195.11 OEU10562.1 - 0.04 13.8 0.2 0.18 11.7 0.2 2.1 1 0 0 1 1 1 0 TRI9 protein Nudix_N PF12535.8 OEU10562.1 - 0.21 11.2 0.8 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF4179 PF13786.6 OEU10563.1 - 0.18 12.3 0.8 0.33 11.5 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) CNOT1_CAF1_bind PF16415.5 OEU10564.1 - 3.9e-76 255.4 0.0 4.5e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3871 PF12987.7 OEU10564.1 - 0.065 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) SF3A3 PF16837.5 OEU10564.1 - 0.11 13.0 0.2 0.62 10.6 0.2 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Not1 PF04054.15 OEU10565.1 - 2.7e-99 332.6 0.2 3e-99 332.4 0.2 1.0 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 Dioxygenase_C PF00775.21 OEU10566.1 - 5.2e-16 58.6 0.6 4.3e-14 52.4 0.6 2.0 1 1 0 1 1 1 1 Dioxygenase TTR-52 PF01060.23 OEU10566.1 - 0.13 13.0 0.0 0.36 11.6 0.0 1.7 1 1 0 1 1 1 0 Transthyretin-like family DUF3228 PF11539.8 OEU10567.1 - 8.7e-74 247.2 0.0 9.8e-74 247.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Peptidase_C1 PF00112.23 OEU10568.1 - 8.8e-17 61.9 11.8 2.9e-15 57.0 3.3 2.8 1 1 2 3 3 3 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 OEU10568.1 - 4.4e-07 30.2 0.5 4.4e-07 30.2 0.5 2.2 3 0 0 3 3 3 1 Cathepsin propeptide inhibitor domain (I29) MatE PF01554.18 OEU10569.1 - 1.4e-10 41.1 10.9 1.4e-10 41.1 10.9 3.3 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU10569.1 - 4.9e-09 36.4 3.0 4.9e-09 36.4 3.0 3.1 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF493 PF04359.14 OEU10570.1 - 9.8e-19 67.7 0.0 1.9e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF493) ACT_4 PF13291.6 OEU10570.1 - 0.13 12.8 0.0 0.21 12.2 0.0 1.2 1 0 0 1 1 1 0 ACT domain AA_kinase PF00696.28 OEU10571.1 - 9.1e-23 81.1 0.0 1.9e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 Amino acid kinase family BES1_N PF05687.13 OEU10571.1 - 0.0025 18.2 0.3 0.019 15.4 0.0 2.4 3 0 0 3 3 3 1 BES1/BZR1 plant transcription factor, N-terminal BRK PF07533.16 OEU10571.1 - 0.081 12.6 0.3 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 BRK domain Mito_carr PF00153.27 OEU10572.1 - 5.3e-33 112.8 0.0 5.5e-14 51.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CBP_BcsO PF17037.5 OEU10572.1 - 0.087 13.0 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO E7 PF00527.18 OEU10572.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 E7 protein, Early protein mTERF PF02536.14 OEU10573.1 - 4.3e-43 147.4 0.3 1.6e-15 56.9 0.0 4.3 2 1 0 3 3 3 3 mTERF Defensin_1 PF00323.19 OEU10574.1 - 0.026 15.1 1.1 0.026 15.1 1.1 2.4 2 0 0 2 2 2 0 Mammalian defensin zf-CCHH PF10283.9 OEU10574.1 - 0.4 10.7 1.3 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 PBZ domain CASP_C PF08172.12 OEU10575.1 - 4.1e-55 186.9 8.3 4.1e-55 186.9 8.3 4.2 3 3 1 5 5 5 1 CASP C terminal RasGAP_C PF03836.15 OEU10575.1 - 0.0036 17.4 0.5 0.0036 17.4 0.5 5.4 5 1 1 6 6 6 3 RasGAP C-terminus BLOC1_2 PF10046.9 OEU10575.1 - 0.0047 17.2 6.4 0.0047 17.2 6.4 6.0 5 0 0 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 OEU10575.1 - 0.07 13.3 30.9 0.61 10.3 3.3 6.0 5 0 0 5 5 5 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 OEU10575.1 - 0.39 10.8 33.7 3.6 7.7 0.1 8.4 7 1 1 8 8 8 0 bZIP transcription factor DUF2935 PF11155.8 OEU10575.1 - 1.6 9.1 17.8 3.2 8.1 0.1 5.0 4 1 0 4 4 4 0 Domain of unknown function (DUF2935) Ribosomal_S18 PF01084.20 OEU10576.1 - 4.4e-16 58.8 1.0 4.7e-16 58.7 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S18 Hydrolase_4 PF12146.8 OEU10578.1 - 3.4e-11 42.9 0.0 6.8e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU10578.1 - 6.1e-11 43.3 0.0 2.1e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU10578.1 - 2.2e-10 40.6 0.3 8.3e-10 38.7 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OEU10578.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Phage_fiber_2 PF03406.13 OEU10578.1 - 0.24 11.0 0.8 0.74 9.4 0.3 1.9 2 0 0 2 2 2 0 Phage tail fibre repeat Actin PF00022.19 OEU10579.1 - 4.4e-102 341.7 0.0 9.1e-101 337.4 0.0 2.5 1 1 0 1 1 1 1 Actin Beta_helix PF13229.6 OEU10580.1 - 0.044 13.6 0.2 0.14 12.0 0.2 1.7 1 1 0 1 1 1 0 Right handed beta helix region PARM PF17061.5 OEU10580.1 - 0.51 10.4 19.2 0.7 10.0 19.2 1.1 1 0 0 1 1 1 0 PARM Retinal PF15449.6 OEU10580.1 - 4 5.1 19.6 4.8 4.8 19.6 1.0 1 0 0 1 1 1 0 Retinal protein Arrestin_N PF00339.29 OEU10582.1 - 0.001 19.2 1.9 0.0023 18.0 0.1 2.7 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Vps4_C PF09336.10 OEU10583.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain EnY2 PF10163.9 OEU10584.1 - 4.7e-10 39.7 0.0 6.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 ABC_membrane PF00664.23 OEU10585.1 - 3.4e-50 171.2 15.9 8e-27 94.6 5.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU10585.1 - 1.2e-48 165.1 0.8 1.5e-28 100.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OEU10585.1 - 4.3e-13 49.2 0.3 0.00023 20.6 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU10585.1 - 2.5e-05 24.3 1.6 0.096 12.8 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OEU10585.1 - 6.4e-05 23.4 1.2 0.082 13.3 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OEU10585.1 - 0.00013 22.2 0.1 0.086 13.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OEU10585.1 - 0.00022 20.9 0.8 0.85 9.4 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OEU10585.1 - 0.00065 19.6 0.1 2.4 7.9 0.1 3.8 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 OEU10585.1 - 0.0088 15.6 0.2 0.32 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 OEU10585.1 - 0.013 15.7 1.1 0.89 9.8 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Spore_IV_A PF09547.10 OEU10585.1 - 0.021 13.8 0.2 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) AAA_33 PF13671.6 OEU10585.1 - 0.025 14.7 0.1 0.42 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OEU10585.1 - 0.047 13.7 0.3 0.047 13.7 0.3 3.1 4 0 0 4 4 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 OEU10585.1 - 0.075 12.4 0.3 3.1 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 OEU10585.1 - 0.094 12.0 1.6 11 5.2 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin RsgA_GTPase PF03193.16 OEU10585.1 - 0.15 12.0 1.9 12 5.8 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 OEU10585.1 - 0.18 11.9 2.9 2.9 7.9 0.9 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain Pox_A32 PF04665.12 OEU10585.1 - 0.26 10.7 0.6 2.5 7.5 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Tmemb_14 PF03647.13 OEU10585.1 - 3.3 8.5 14.8 0.045 14.5 3.4 3.4 4 0 0 4 4 3 0 Transmembrane proteins 14C DEP PF00610.21 OEU10586.1 - 4.8e-13 49.0 0.2 1.1e-12 47.8 0.2 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IDO PF01231.18 OEU10586.1 - 1.2e-09 37.5 0.0 8.7e-06 24.8 0.0 2.4 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase zf-RVT PF13966.6 OEU10586.1 - 0.058 14.1 0.5 19 6.0 0.1 2.8 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase zf-C2HC PF01530.18 OEU10586.1 - 0.058 13.6 7.4 3.6 7.9 0.1 4.9 4 0 0 4 4 4 0 Zinc finger, C2HC type NAD_binding_1 PF00175.21 OEU10586.1 - 0.071 13.8 0.0 0.22 12.2 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 OEU10586.1 - 0.1 12.1 0.0 0.66 9.5 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Fer4_11 PF13247.6 OEU10586.1 - 0.28 11.3 1.0 18 5.5 0.1 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain CDC45 PF02724.14 OEU10586.1 - 0.33 9.2 0.0 0.33 9.2 0.0 2.7 3 0 0 3 3 3 0 CDC45-like protein 2OG-FeII_Oxy_3 PF13640.6 OEU10588.1 - 8.7e-16 58.6 0.1 1.4e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU10588.1 - 0.022 15.4 0.1 0.05 14.3 0.1 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2782 PF11191.8 OEU10588.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Tfb4 PF03850.14 OEU10589.1 - 2.3e-46 158.5 0.0 2.8e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C3HC4_3 PF13920.6 OEU10589.1 - 0.07 13.0 1.1 0.13 12.2 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 OEU10589.1 - 0.15 11.7 0.7 0.3 10.8 0.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger Amino_oxidase PF01593.24 OEU10590.1 - 1.8e-50 172.6 0.0 7.7e-50 170.5 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU10590.1 - 1.9e-13 50.4 0.2 8e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU10590.1 - 2.3e-05 23.8 0.0 3.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OEU10590.1 - 3.3e-05 23.2 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OEU10590.1 - 0.00011 22.2 0.5 0.00074 19.5 0.2 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OEU10590.1 - 0.00036 20.2 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OEU10590.1 - 0.0005 18.9 0.0 0.00093 18.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OEU10590.1 - 0.0017 17.6 1.0 0.0027 17.0 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OEU10590.1 - 0.0063 15.6 0.6 0.039 13.0 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OEU10590.1 - 0.033 13.5 0.1 0.084 12.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 OEU10590.1 - 0.093 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OEU10590.1 - 0.59 10.7 4.7 0.72 10.4 0.2 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SMC_N PF02463.19 OEU10591.1 - 2.8e-17 62.9 17.8 4.8e-17 62.1 17.8 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OEU10591.1 - 4.1e-15 56.8 27.4 4.1e-15 56.8 27.4 5.4 2 2 2 4 4 4 1 AAA domain SMC_hinge PF06470.13 OEU10591.1 - 0.0017 18.6 0.5 0.0064 16.8 0.1 2.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OEU10591.1 - 0.0018 18.1 0.1 0.0018 18.1 0.1 3.5 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 OEU10591.1 - 0.0051 16.4 0.0 0.0051 16.4 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 OEU10591.1 - 0.0062 17.0 0.7 0.74 10.2 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU10591.1 - 0.02 14.4 0.1 0.21 11.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OEU10591.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FlgD_ig PF13860.6 OEU10591.1 - 0.12 12.3 0.2 0.29 11.0 0.2 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain SpoU_sub_bind PF08032.12 OEU10591.1 - 0.57 10.5 0.0 0.57 10.5 0.0 5.2 6 1 1 7 7 7 0 RNA 2'-O ribose methyltransferase substrate binding TetR_C_15 PF17918.1 OEU10592.1 - 0.14 12.9 0.0 0.53 11.1 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RabGAP-TBC PF00566.18 OEU10593.1 - 2.9e-51 174.2 0.0 6.4e-51 173.1 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC53 PF10152.9 OEU10594.1 - 2.1e-31 109.4 42.0 1.8e-07 31.7 5.3 7.2 3 2 3 6 6 6 5 Subunit CCDC53 of WASH complex dbPDZ_assoc PF16610.5 OEU10594.1 - 0.00075 19.7 14.7 0.18 12.0 2.2 5.1 4 0 0 4 4 4 3 Unstructured region between two PDZ domains on Dlg5 DUF2884 PF11101.8 OEU10594.1 - 0.0016 18.0 0.3 1.2 8.6 0.2 3.9 3 1 0 4 4 4 1 Protein of unknown function (DUF2884) GST_N_4 PF17172.4 OEU10594.1 - 0.13 13.0 0.4 3.1e+02 2.2 0.0 4.5 5 0 0 5 5 5 0 Glutathione S-transferase N-terminal domain MatE PF01554.18 OEU10595.1 - 1.9e-09 37.4 30.9 8.3e-08 32.0 13.5 3.2 2 2 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU10595.1 - 4.2e-07 30.1 0.7 4.2e-07 30.1 0.7 3.4 3 2 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain PD-C2-AF1 PF09310.10 OEU10595.1 - 0.064 12.7 0.3 0.15 11.4 0.3 1.6 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 TPR_12 PF13424.6 OEU10596.1 - 1.6e-05 25.1 0.1 0.01 16.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Phage_B PF02304.15 OEU10596.1 - 0.35 11.2 4.1 23 5.4 0.2 3.9 2 1 2 4 4 4 0 Scaffold protein B PulG PF11773.8 OEU10596.1 - 8 6.4 6.4 60 3.6 0.2 4.1 3 1 0 4 4 4 0 Type II secretory pathway pseudopilin IFRD PF05004.13 OEU10598.1 - 3.4e-33 115.1 0.1 4.9e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OEU10598.1 - 0.034 14.7 1.7 20 5.8 0.7 3.2 2 1 2 4 4 4 0 HEAT-like repeat IFRD_C PF04836.12 OEU10598.1 - 0.054 14.1 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 Interferon-related protein conserved region RRN3 PF05327.11 OEU10598.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_1 PF00561.20 OEU10599.1 - 4.2e-06 26.6 0.0 1.5e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU10599.1 - 0.052 12.8 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Bromodomain PF00439.25 OEU10600.1 - 7e-16 58.1 0.0 8.1e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 OEU10601.1 - 4.6e-07 30.4 0.1 1.5e-06 28.7 0.1 1.9 1 1 0 1 1 1 1 SET domain Ribosomal_L37e PF01907.19 OEU10602.1 - 3.8e-28 97.4 15.4 3.8e-28 97.4 15.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 OEU10602.1 - 0.015 15.3 2.2 0.023 14.7 2.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 OEU10602.1 - 0.16 12.0 1.7 0.24 11.4 1.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 OEU10602.1 - 0.18 11.3 3.9 0.39 10.2 3.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF2688 PF10892.8 OEU10602.1 - 0.55 9.7 5.7 0.24 10.9 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) zn-ribbon_14 PF16503.5 OEU10602.1 - 1.3 8.6 6.4 2 8.0 0.6 2.2 2 0 0 2 2 2 0 Zinc-ribbon zf-HYPF PF07503.12 OEU10602.1 - 1.9 8.3 5.9 10 6.0 0.5 2.3 2 0 0 2 2 2 0 HypF finger YhfH PF14149.6 OEU10602.1 - 2 8.5 6.2 1.6 8.8 0.8 2.3 1 1 1 2 2 2 0 YhfH-like protein tRNA-synt_2b PF00587.25 OEU10603.1 - 4e-42 144.2 0.0 1e-41 142.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OEU10603.1 - 6.3e-19 67.9 0.1 2e-18 66.3 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OEU10603.1 - 7.8e-14 51.5 0.0 1.8e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain VWA PF00092.28 OEU10604.1 - 0.019 15.2 0.0 0.13 12.5 0.0 2.3 2 1 0 2 2 2 0 von Willebrand factor type A domain NHase_beta PF02211.15 OEU10605.1 - 0.071 13.1 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Cyclin PF08613.11 OEU10606.1 - 9e-35 120.4 0.4 9e-35 120.4 0.4 2.4 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 OEU10606.1 - 8.4e-11 41.7 0.3 2.2e-10 40.4 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain PEX11 PF05648.14 OEU10607.1 - 4.7e-21 75.3 6.4 1.3e-12 47.7 0.2 2.8 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Nucleoside_tran PF01733.18 OEU10607.1 - 0.31 10.4 4.0 0.061 12.7 0.4 1.6 2 0 0 2 2 2 0 Nucleoside transporter RP-C_C PF11800.8 OEU10607.1 - 2.6 8.1 6.4 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Vfa1 PF08432.10 OEU10607.1 - 9.8 6.5 11.4 0.97 9.7 0.2 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mpv17_PMP22 PF04117.12 OEU10608.1 - 8.8e-08 32.3 0.4 1.6e-07 31.4 0.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3395 PF11875.8 OEU10609.1 - 2.9e-20 72.8 0.0 2.9e-20 72.8 0.0 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3395) DUF2240 PF09999.9 OEU10609.1 - 0.0027 17.3 1.2 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2240) Flu_NS1 PF00600.19 OEU10609.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Efg1 PF10153.9 OEU10610.1 - 1.4e-13 51.2 10.3 1.4e-13 51.2 10.3 3.7 2 2 0 2 2 2 1 rRNA-processing protein Efg1 Utp14 PF04615.13 OEU10610.1 - 0.045 12.3 67.8 0.09 11.3 67.8 1.4 1 1 0 1 1 1 0 Utp14 protein Alg6_Alg8 PF03155.15 OEU10612.1 - 3.3e-123 412.2 18.8 5.4e-123 411.5 18.8 1.3 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPR_12 PF13424.6 OEU10613.1 - 5.3e-37 126.0 3.6 2.6e-10 40.4 0.6 6.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10613.1 - 2.1e-20 71.6 5.1 0.0019 17.9 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 OEU10613.1 - 6.5e-20 70.4 11.1 2.9e-05 23.8 0.1 8.2 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10613.1 - 6.3e-17 60.3 7.1 0.053 13.7 0.1 8.9 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU10613.1 - 8.8e-16 56.7 13.6 0.014 15.5 0.1 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU10613.1 - 2e-14 53.7 2.4 3.1e-09 36.7 0.5 4.1 3 2 1 4 4 4 2 MalT-like TPR region TPR_7 PF13176.6 OEU10613.1 - 5.1e-13 48.1 10.6 0.0049 16.8 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 OEU10613.1 - 6.4e-06 26.2 0.8 1.6 9.3 0.0 5.0 5 0 0 5 5 3 2 Tetratricopeptide repeat MIT PF04212.18 OEU10613.1 - 7.7e-06 25.9 10.4 1.4 9.0 0.1 6.8 8 0 0 8 8 8 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 OEU10613.1 - 1.1e-05 25.8 3.3 4.9 8.2 0.1 6.7 8 1 1 9 9 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10613.1 - 1.4e-05 25.4 5.6 1.6 9.6 0.2 5.4 7 0 0 7 7 4 2 Tetratricopeptide repeat SNAP PF14938.6 OEU10613.1 - 5.3e-05 22.8 1.4 0.13 11.7 0.0 4.8 3 2 1 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 OEU10613.1 - 0.00021 20.9 18.1 6.7 6.5 0.9 7.0 7 0 0 7 7 7 1 TPR repeat TPR_19 PF14559.6 OEU10613.1 - 0.012 16.1 3.2 1.4 9.5 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU10613.1 - 0.025 15.2 0.4 13 6.6 0.8 4.3 4 2 0 4 4 4 0 Tetratricopeptide repeat DUF5113 PF17140.4 OEU10613.1 - 0.22 11.3 6.3 2.1 8.2 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) HEPN PF05168.14 OEU10613.1 - 0.33 11.1 3.3 1.1 9.4 0.2 3.0 3 0 0 3 3 3 0 HEPN domain PNTB PF02233.16 OEU10616.1 - 2.9e-163 544.1 23.9 2.9e-163 544.1 23.9 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OEU10616.1 - 3.4e-69 232.4 3.4 3.4e-69 232.4 3.4 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OEU10616.1 - 3e-39 134.4 0.0 1.7e-38 132.0 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OEU10616.1 - 8.4e-27 93.5 0.9 8.4e-27 93.5 0.9 4.2 3 1 2 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Methyltransf_16 PF10294.9 OEU10616.1 - 0.00046 20.0 2.1 0.1 12.3 0.0 4.0 4 0 0 4 4 4 1 Lysine methyltransferase 2-Hacid_dh_C PF02826.19 OEU10616.1 - 0.00057 19.3 0.2 0.27 10.6 0.1 3.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OEU10616.1 - 0.012 15.6 1.2 0.035 14.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Tic22 PF04278.12 OEU10617.1 - 2.8e-12 46.5 0.7 2.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Tic22-like family Peptidase_S49 PF01343.18 OEU10618.1 - 1.6e-26 93.1 0.0 4.8e-26 91.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S49 DUF1336 PF07059.12 OEU10619.1 - 8.4e-54 183.0 0.0 1e-53 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) TMEM164 PF14808.6 OEU10620.1 - 4.9e-18 65.4 17.2 7.7e-18 64.7 17.2 1.2 1 0 0 1 1 1 1 TMEM164 family SAM_2 PF07647.17 OEU10622.1 - 5.7e-11 42.4 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OEU10622.1 - 1.8e-07 31.5 0.0 3.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UBX PF00789.20 OEU10623.1 - 3.3e-05 24.0 0.0 0.00014 22.0 0.0 2.0 2 0 0 2 2 2 1 UBX domain Herpes_US12 PF05363.12 OEU10623.1 - 0.02 15.6 0.2 0.063 14.0 0.2 1.9 1 0 0 1 1 1 0 Herpesvirus US12 family DUF3069 PF11269.8 OEU10623.1 - 0.043 14.1 0.6 0.043 14.1 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3069) Csm4_C PF17953.1 OEU10623.1 - 0.13 12.1 0.4 0.37 10.7 0.4 1.7 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain DUF1666 PF07891.12 OEU10623.1 - 1.3 8.6 11.1 2.9 7.5 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1666) Asp_Arg_Hydrox PF05118.15 OEU10624.1 - 2.7e-40 137.8 0.0 3.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Raptor_N PF14538.6 OEU10624.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF5344 PF17279.2 OEU10624.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Pep3_Vps18 PF05131.14 OEU10625.1 - 3.5e-13 49.6 0.0 1.5e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 OEU10625.1 - 0.096 13.1 0.0 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 ODV-E18 PF10717.9 OEU10625.1 - 7.8 6.5 8.8 5 7.1 2.1 2.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3164 PF11363.8 OEU10626.1 - 0.074 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) zf-Tim10_DDP PF02953.15 OEU10627.1 - 4.6e-17 61.4 9.2 6.5e-17 60.9 9.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 OEU10627.1 - 0.0099 15.6 10.8 0.013 15.2 10.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) eIF3_subunit PF08597.10 OEU10627.1 - 0.034 14.1 0.6 0.039 13.9 0.6 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Nuf2 PF03800.14 OEU10627.1 - 0.078 13.1 0.9 0.088 12.9 0.9 1.1 1 0 0 1 1 1 0 Nuf2 family Gluconate_2-dh3 PF13618.6 OEU10627.1 - 0.47 10.7 3.4 1.1 9.5 3.4 1.7 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 MgtE PF01769.16 OEU10628.1 - 4.1e-14 53.0 3.4 6.8e-14 52.3 3.4 1.3 1 0 0 1 1 1 1 Divalent cation transporter DUF3094 PF11293.8 OEU10628.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) DUF3021 PF11457.8 OEU10628.1 - 1.1 9.6 7.1 2.1 8.7 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF3487 PF11990.8 OEU10628.1 - 7.3 6.5 5.6 22 5.0 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) HIRAN PF08797.11 OEU10629.1 - 3e-18 65.5 0.0 1.9e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 HIRAN domain zf-PARP PF00645.18 OEU10629.1 - 6.6e-08 33.3 0.4 6.6e-08 33.3 0.4 2.4 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ank_5 PF13857.6 OEU10630.1 - 2.4e-08 34.1 0.0 3.4e-07 30.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 OEU10630.1 - 9e-07 29.7 0.0 2.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 OEU10630.1 - 3e-05 24.5 0.0 0.0011 19.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU10630.1 - 4.7e-05 23.9 0.0 0.00026 21.5 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) TFIIA PF03153.13 OEU10630.1 - 0.0029 17.7 10.9 0.018 15.0 11.5 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ank PF00023.30 OEU10630.1 - 0.0039 17.6 0.0 0.23 12.0 0.0 3.1 3 0 0 3 3 2 1 Ankyrin repeat Spt20 PF12090.8 OEU10630.1 - 0.0068 16.1 10.9 0.0068 16.1 10.9 2.0 2 0 0 2 2 2 1 Spt20 family 2OG-FeII_Oxy_5 PF13759.6 OEU10630.1 - 0.021 15.3 0.4 6 7.3 0.0 2.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Ank_3 PF13606.6 OEU10630.1 - 0.021 15.3 0.0 0.94 10.2 0.0 3.3 3 0 0 3 3 2 0 Ankyrin repeat zf-C3HC4_2 PF13923.6 OEU10630.1 - 0.043 13.7 4.0 0.16 11.8 4.0 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sld3_N PF18523.1 OEU10630.1 - 0.059 13.5 0.6 0.18 11.9 0.6 1.9 1 0 0 1 1 1 0 Sld3 N-terminal domain DUF3464 PF11947.8 OEU10630.1 - 0.12 12.1 0.8 0.33 10.7 0.8 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pet20 PF08692.10 OEU10630.1 - 0.31 11.8 1.9 0.57 10.9 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet20 TMEM51 PF15345.6 OEU10630.1 - 0.39 10.5 4.0 0.15 11.8 0.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 zf-RING_UBOX PF13445.6 OEU10630.1 - 1.2 9.2 12.2 0.051 13.6 2.7 3.1 3 0 0 3 3 2 0 RING-type zinc-finger Cys_rich_CPCC PF14206.6 OEU10630.1 - 3.7 7.4 7.3 1 9.2 2.5 2.5 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-RING_5 PF14634.6 OEU10630.1 - 8.1 6.5 13.4 0.73 9.8 5.6 2.8 2 0 0 2 2 2 0 zinc-RING finger domain DUF826 PF05696.11 OEU10631.1 - 0.002 18.2 0.6 1.8 8.7 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF826) Ribosomal_S22 PF08136.11 OEU10631.1 - 0.074 13.4 0.2 77 3.8 0.0 3.2 3 0 0 3 3 3 0 30S ribosomal protein subunit S22 family Pheromone PF08015.11 OEU10631.1 - 0.39 11.8 11.3 13 6.9 0.1 4.1 1 1 3 4 4 4 0 Fungal mating-type pheromone Methyltransf_24 PF13578.6 OEU10633.1 - 0.00051 21.0 0.0 0.00097 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.19 OEU10634.1 - 5.6e-07 29.1 0.1 1.1e-06 28.1 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 OEU10634.1 - 0.006 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Secretin_N_2 PF07655.13 OEU10634.1 - 8.7 7.0 12.6 25 5.5 6.7 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain HTH_Tnp_Tc3_1 PF11427.8 OEU10635.1 - 0.023 14.5 0.2 0.059 13.2 0.2 1.7 1 0 0 1 1 1 0 Tc3 transposase Prothymosin PF03247.14 OEU10635.1 - 0.27 11.7 10.7 0.81 10.2 10.7 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family Hydrolase_3 PF08282.12 OEU10635.1 - 0.32 10.7 7.6 0.038 13.7 2.9 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NOA36 PF06524.12 OEU10635.1 - 5.9 6.1 13.9 0.26 10.5 7.5 1.9 2 0 0 2 2 2 0 NOA36 protein ANAPC10 PF03256.16 OEU10637.1 - 4e-54 183.1 0.1 5.5e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 OEU10637.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 OEU10637.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 PITH domain Inositol_P PF00459.25 OEU10638.1 - 5.8e-35 121.1 0.0 1e-34 120.3 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Peripla_BP_2 PF01497.18 OEU10639.1 - 8.9e-10 38.5 0.0 1.5e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein PLDc_2 PF13091.6 OEU10640.1 - 4.4e-12 46.0 0.0 1.9e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OEU10640.1 - 0.042 14.0 4.6 0.6 10.4 0.2 3.2 3 0 0 3 3 3 0 Phospholipase D Active site motif DinI PF06183.13 OEU10640.1 - 0.054 13.8 0.1 16 5.9 0.0 2.5 2 0 0 2 2 2 0 DinI-like family AAA PF00004.29 OEU10641.1 - 4.7e-41 140.3 0.1 1.1e-40 139.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU10641.1 - 1.7e-10 40.5 0.2 3.4e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OEU10641.1 - 4.7e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OEU10641.1 - 1.6e-06 28.1 0.1 1.2e-05 25.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU10641.1 - 1.8e-05 25.0 0.2 0.012 15.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OEU10641.1 - 2.2e-05 24.6 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OEU10641.1 - 2.8e-05 23.4 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OEU10641.1 - 3.2e-05 24.4 0.1 0.0012 19.3 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OEU10641.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OEU10641.1 - 0.01 15.2 0.1 0.23 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.22 OEU10641.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OEU10641.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OEU10641.1 - 0.021 14.0 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 OEU10641.1 - 0.022 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OEU10641.1 - 0.029 14.1 0.1 0.12 12.0 0.1 2.0 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 OEU10641.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 OEU10641.1 - 0.034 14.4 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU10641.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 OEU10641.1 - 0.05 13.2 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 OEU10641.1 - 0.052 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU10641.1 - 0.053 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OEU10641.1 - 0.075 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OEU10641.1 - 0.089 12.7 0.3 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 OEU10641.1 - 0.12 12.1 0.1 0.28 10.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OEU10641.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OEU10641.1 - 0.12 11.8 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 OEU10641.1 - 0.13 11.5 0.0 0.37 9.9 0.0 1.7 2 0 0 2 2 1 0 NB-ARC domain AAA_7 PF12775.7 OEU10641.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 OEU10641.1 - 0.13 11.8 0.4 0.55 9.8 0.1 2.0 1 1 1 2 2 2 0 AAA domain SNF2_N PF00176.23 OEU10642.1 - 5.7e-57 193.0 0.0 8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU10642.1 - 3.6e-17 62.7 0.0 8.2e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU10642.1 - 1.5e-10 41.4 0.0 3.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU10642.1 - 6.1e-08 32.2 0.4 1.3e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU10642.1 - 0.0004 20.2 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OEU10642.1 - 0.0029 17.3 0.0 0.007 16.1 0.0 1.6 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Glyco_trans_1_2 PF13524.6 OEU10642.1 - 0.075 13.4 0.0 2.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 Glyco_transf_41 PF13844.6 OEU10643.1 - 5.7e-25 87.7 0.0 4.1e-13 48.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 Fis1_TPR_C PF14853.6 OEU10643.1 - 4.3e-06 26.7 0.6 2.2e-05 24.4 0.1 2.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 OEU10643.1 - 0.00023 21.1 1.4 0.72 10.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10643.1 - 0.00072 19.3 2.2 0.095 12.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 OEU10643.1 - 0.0033 17.4 0.2 0.35 10.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU10643.1 - 0.014 14.9 0.3 0.08 12.4 0.3 2.0 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 OEU10643.1 - 0.02 15.7 0.1 6.4 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU10643.1 - 0.026 14.8 0.6 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OEU10643.1 - 0.11 12.7 2.0 6.7 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NPL4 PF05021.15 OEU10644.1 - 4.7e-27 95.1 0.5 1.7e-21 76.9 0.5 3.1 1 1 1 2 2 2 2 NPL4 family WD40 PF00400.32 OEU10644.1 - 5.2e-14 52.4 11.8 0.00027 21.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat MIF4G PF02854.19 OEU10647.1 - 3.1e-34 118.5 12.5 7.1e-34 117.3 9.7 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 OEU10647.1 - 3.1e-05 23.9 3.0 0.00013 21.9 0.1 3.0 3 0 0 3 3 3 1 MA3 domain GRP PF07172.11 OEU10647.1 - 0.0046 17.6 16.9 0.0046 17.6 16.9 1.8 2 0 0 2 2 2 1 Glycine rich protein family CrgA PF06781.12 OEU10648.1 - 0.012 15.7 0.5 0.044 13.8 0.5 2.0 1 0 0 1 1 1 0 Cell division protein CrgA CLN3 PF02487.17 OEU10648.1 - 0.019 14.0 1.5 0.028 13.5 0.4 1.8 2 0 0 2 2 2 0 CLN3 protein eIF-3_zeta PF05091.12 OEU10649.1 - 0.0017 17.5 13.4 0.002 17.2 13.4 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Eapp_C PF10238.9 OEU10649.1 - 0.008 16.3 14.5 0.026 14.6 14.5 1.9 1 1 0 1 1 1 1 E2F-associated phosphoprotein Connexin PF00029.19 OEU10649.1 - 0.014 15.2 7.3 0.024 14.4 7.3 1.4 1 0 0 1 1 1 0 Connexin DUF2417 PF10329.9 OEU10649.1 - 0.016 14.6 3.9 0.032 13.7 3.8 1.6 1 1 0 1 1 1 0 Region of unknown function (DUF2417) Pex14_N PF04695.13 OEU10649.1 - 0.018 15.7 16.3 0.018 15.7 16.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3043 PF11241.8 OEU10649.1 - 0.028 14.5 2.4 0.044 13.8 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2126 PF09899.9 OEU10649.1 - 0.031 12.4 4.7 0.036 12.1 4.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PepSY_TM PF03929.16 OEU10649.1 - 0.15 11.7 1.1 0.16 11.6 1.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF4407 PF14362.6 OEU10649.1 - 0.26 10.6 10.6 0.41 10.0 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RPN2_C PF18004.1 OEU10649.1 - 0.31 11.0 21.2 0.16 11.9 13.2 2.4 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 OEU10649.1 - 0.32 8.9 14.3 0.49 8.3 14.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 OEU10649.1 - 0.6 9.8 10.7 1 9.0 10.7 1.4 1 0 0 1 1 1 0 FAM176 family PPL5 PF18168.1 OEU10649.1 - 0.69 9.2 9.5 1.2 8.3 9.5 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Tim54 PF11711.8 OEU10649.1 - 2.1 7.0 18.7 2.7 6.7 17.2 1.7 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 OEU10649.1 - 2.3 8.2 13.1 0.72 9.9 10.0 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4050 PF13259.6 OEU10649.1 - 5.9 7.2 17.6 1.6 9.1 12.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Peptidase_S49_N PF08496.10 OEU10649.1 - 9.9 6.2 16.8 1.7 8.7 12.9 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Gly_transf_sug PF04488.15 OEU10650.1 - 0.017 15.7 0.0 0.061 13.9 0.0 2.0 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif AAA PF00004.29 OEU10651.1 - 6.1e-39 133.5 0.0 9.1e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU10651.1 - 8.5e-11 41.5 0.5 1.7e-10 40.5 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OEU10651.1 - 9.2e-06 26.1 0.0 0.0067 16.8 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 OEU10651.1 - 0.0001 22.3 0.1 0.00045 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU10651.1 - 0.00012 22.3 0.2 0.028 14.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OEU10651.1 - 0.00033 20.5 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OEU10651.1 - 0.00054 19.8 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OEU10651.1 - 0.0024 17.3 0.4 0.0053 16.2 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OEU10651.1 - 0.0041 17.3 0.1 0.013 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OEU10651.1 - 0.0049 16.9 0.0 0.28 11.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OEU10651.1 - 0.021 14.9 0.0 0.073 13.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 OEU10651.1 - 0.028 14.0 0.7 0.33 10.5 0.2 2.2 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 OEU10651.1 - 0.032 13.4 0.1 0.074 12.2 0.1 1.5 1 1 1 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 OEU10651.1 - 0.033 14.1 0.1 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 OEU10651.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OEU10651.1 - 0.04 14.3 0.0 0.056 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU10651.1 - 0.049 13.9 0.1 0.095 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OEU10651.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 OEU10651.1 - 0.11 11.9 0.4 0.26 10.7 0.3 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 OEU10651.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.7 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 OEU10651.1 - 0.23 11.2 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF5316 PF17247.2 OEU10652.1 - 0.17 11.9 0.8 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5316) PTEN_C2 PF10409.9 OEU10653.1 - 3e-19 69.1 0.0 8.9e-19 67.6 0.0 1.9 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OEU10653.1 - 0.0011 18.8 0.1 0.0065 16.3 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OEU10653.1 - 0.0019 18.3 1.5 0.043 13.9 0.0 3.3 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OEU10653.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Nuc_sug_transp PF04142.15 OEU10654.1 - 1.1e-12 47.7 5.7 1.6e-12 47.2 5.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OEU10654.1 - 0.0021 17.3 0.8 0.0021 17.3 0.8 2.0 1 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 OEU10654.1 - 0.0027 17.9 15.2 0.013 15.6 10.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPR_12 PF13424.6 OEU10655.1 - 0.00056 20.2 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10655.1 - 0.006 16.5 0.1 0.35 11.0 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU10655.1 - 0.0081 16.3 0.5 0.65 10.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10655.1 - 0.015 15.4 0.0 3.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 OEU10655.1 - 0.015 15.5 4.4 0.015 15.5 4.4 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_1 PF00515.28 OEU10655.1 - 0.016 15.0 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU10655.1 - 0.016 15.8 0.2 3.1 8.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU10655.1 - 0.031 14.8 0.0 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OEU10655.1 - 0.063 13.0 0.1 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 TPR repeat MIT PF04212.18 OEU10655.1 - 0.15 12.2 1.5 1 9.5 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RPT PF13446.6 OEU10655.1 - 0.17 11.9 1.2 0.37 10.8 0.3 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein Fez1 PF06818.15 OEU10655.1 - 1.1 9.6 10.0 0.47 10.9 6.7 1.8 1 1 0 2 2 2 0 Fez1 YlqD PF11068.8 OEU10655.1 - 8.8 6.7 9.4 2.4 8.6 4.8 2.4 3 1 0 3 3 3 0 YlqD protein Methyltransf_16 PF10294.9 OEU10656.1 - 4.8e-28 98.1 0.0 7e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase TFIIE-A_C PF11521.8 OEU10656.1 - 5e-05 23.5 1.8 0.0004 20.6 0.2 2.3 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Methyltransf_23 PF13489.6 OEU10656.1 - 0.0097 15.8 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU10656.1 - 0.036 14.8 0.0 0.084 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PP1_bind PF15276.6 OEU10657.1 - 0.095 13.0 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 1 binding DUF3602 PF12223.8 OEU10657.1 - 0.13 12.9 0.4 0.36 11.4 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3602) Asp_Arg_Hydrox PF05118.15 OEU10658.1 - 3.8e-38 130.8 0.0 5.1e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF1366 PF07104.11 OEU10659.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) SecA_DEAD PF07517.14 OEU10659.1 - 0.079 12.2 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain DUF543 PF04418.12 OEU10659.1 - 0.68 10.0 2.6 1.2 9.2 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Ribosomal_L7Ae PF01248.26 OEU10660.1 - 7e-21 73.8 0.0 7.6e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4684 PF15736.5 OEU10660.1 - 0.25 10.0 0.0 0.29 9.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) GYF PF02213.16 OEU10661.1 - 4.2e-15 55.1 0.7 8.3e-15 54.2 0.7 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OEU10661.1 - 0.0052 16.6 0.3 0.015 15.1 0.3 1.8 1 0 0 1 1 1 1 GYF domain 2 PWI PF01480.17 OEU10661.1 - 0.073 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 PWI domain Pro_isomerase PF00160.21 OEU10662.1 - 9.1e-44 149.5 0.2 1e-43 149.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 OEU10663.1 - 1.2e-27 97.0 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10663.1 - 1.7e-23 83.3 0.0 1.9e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU10663.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NnrU PF07298.11 OEU10664.1 - 7.5e-06 25.6 0.1 0.039 13.4 0.0 2.2 2 0 0 2 2 2 2 NnrU protein SNARE_assoc PF09335.11 OEU10665.1 - 9.6e-19 68.0 8.7 9.6e-19 68.0 8.7 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein ISAV_HA PF06215.11 OEU10665.1 - 0.037 13.2 0.3 0.086 12.0 0.0 1.6 2 0 0 2 2 2 0 Infectious salmon anaemia virus haemagglutinin RNF220 PF15926.5 OEU10666.1 - 0.0098 15.5 3.2 0.025 14.2 3.2 1.7 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 6PGD PF00393.19 OEU10668.1 - 1.7e-122 408.4 0.1 2e-122 408.1 0.1 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OEU10668.1 - 0.0019 18.4 0.2 0.0037 17.4 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TLC PF03219.14 OEU10669.1 - 1.2e-133 446.5 11.2 1.5e-133 446.1 11.2 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF4227 PF14004.6 OEU10669.1 - 3.1 7.8 5.0 4.5 7.3 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) PRK PF00485.18 OEU10670.1 - 3.5e-69 232.5 0.0 6.3e-69 231.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Glucokinase PF02685.16 OEU10671.1 - 2.2e-38 132.0 0.0 1.6e-22 80.0 0.0 3.7 3 1 0 3 3 3 3 Glucokinase FYDLN_acid PF09538.10 OEU10671.1 - 0.0056 17.3 2.6 0.015 16.0 2.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Dehydrin PF00257.19 OEU10671.1 - 0.044 14.3 1.2 0.1 13.2 1.2 1.6 1 0 0 1 1 1 0 Dehydrin DUF2457 PF10446.9 OEU10671.1 - 0.091 11.9 7.4 0.14 11.3 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 OEU10671.1 - 0.11 12.2 5.8 0.19 11.4 5.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 OEU10671.1 - 0.17 10.8 3.5 0.28 10.1 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 OEU10671.1 - 0.2 9.8 1.7 0.26 9.4 1.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1027 PF06265.11 OEU10671.1 - 0.39 10.7 2.7 0.93 9.5 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) Anophelin PF10731.9 OEU10671.1 - 0.41 10.5 2.6 1.2 9.1 2.6 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF4820 PF16091.5 OEU10671.1 - 0.46 9.8 1.4 0.96 8.8 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNA_pol_phi PF04931.13 OEU10671.1 - 0.76 7.8 9.9 1.1 7.2 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Fasciclin PF02469.22 OEU10672.1 - 9.8e-25 87.2 0.0 9.8e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 Fasciclin domain Mem_trans PF03547.18 OEU10672.1 - 0.00063 18.2 0.5 0.00063 18.2 0.5 1.2 1 0 0 1 1 1 1 Membrane transport protein YL1_C PF08265.11 OEU10672.1 - 0.0029 17.3 0.2 20 5.0 0.0 3.4 3 0 0 3 3 3 2 YL1 nuclear protein C-terminal domain Hid1 PF12722.7 OEU10672.1 - 0.97 7.5 20.7 1.4 6.9 20.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 OEU10672.1 - 9.9 4.4 7.2 16 3.8 7.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAPS_reduct PF01507.19 OEU10673.1 - 2e-26 93.1 0.0 5.2e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 OEU10673.1 - 1.8e-06 27.8 0.1 3.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU10673.1 - 0.018 15.5 0.0 0.08 13.4 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_6 PF13848.6 OEU10673.1 - 0.047 13.6 0.4 0.079 12.9 0.4 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3494 PF11999.8 OEU10674.1 - 7.8e-55 185.7 14.9 7.8e-55 185.7 14.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF4138 PF13595.6 OEU10674.1 - 0.12 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Glyco_tranf_2_4 PF13704.6 OEU10676.1 - 0.00053 20.4 5.5 0.0027 18.2 5.5 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 HA PF03457.14 OEU10677.1 - 2.4e-49 165.5 6.8 4e-16 59.1 0.2 3.1 3 0 0 3 3 3 3 Helicase associated domain PMR5N PF14416.6 OEU10677.1 - 0.00027 21.2 0.3 18 5.7 0.0 4.2 4 0 0 4 4 4 2 PMR5 N terminal Domain Antirestrict PF03230.13 OEU10677.1 - 0.02 14.9 0.0 12 6.0 0.0 3.3 3 0 0 3 3 3 0 Antirestriction protein Peptidase_M15_4 PF13539.6 OEU10677.1 - 0.029 14.9 2.0 0.59 10.7 0.1 2.9 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase BTHB PF18410.1 OEU10678.1 - 0.099 12.5 1.7 1.4 8.8 0.3 2.7 2 0 0 2 2 2 0 Basic tilted helix bundle domain VPS9 PF02204.18 OEU10679.1 - 7.8e-11 42.1 0.1 8.3e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain Bestrophin PF01062.21 OEU10681.1 - 9.1e-21 74.5 3.5 3.7e-10 39.7 0.1 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Sod_Cu PF00080.20 OEU10681.1 - 0.036 14.2 0.8 0.073 13.2 0.8 1.5 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) NAD_binding_10 PF13460.6 OEU10685.1 - 2.4e-13 50.4 0.2 5.4e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OEU10685.1 - 1.1e-05 24.7 0.0 2.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Macoilin PF09726.9 OEU10685.1 - 5 5.6 9.0 3.9 5.9 0.4 2.1 1 1 0 2 2 2 0 Macoilin family YXWGXW PF12779.7 OEU10686.1 - 0.00052 20.1 16.5 0.21 11.8 0.1 4.0 2 1 2 4 4 4 3 YXWGXW repeat (2 copies) AsmA_2 PF13502.6 OEU10686.1 - 0.21 11.1 3.3 0.63 9.5 3.2 1.7 1 1 0 1 1 1 0 AsmA-like C-terminal region HigB-like_toxin PF05015.13 OEU10686.1 - 3.3 8.2 12.8 49 4.4 0.2 4.2 1 1 1 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB CBM_10 PF02013.16 OEU10686.1 - 8.3 7.0 33.4 8.4 7.0 1.5 4.8 1 1 6 7 7 7 0 Cellulose or protein binding domain BET PF17035.5 OEU10687.1 - 0.09 13.0 0.3 0.26 11.5 0.3 1.8 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Nop14 PF04147.12 OEU10688.1 - 0.0038 15.5 12.4 0.0043 15.4 12.4 1.2 1 0 0 1 1 1 1 Nop14-like family Cwf_Cwc_15 PF04889.12 OEU10688.1 - 0.06 13.1 17.5 0.084 12.6 17.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sec62 PF03839.16 OEU10688.1 - 0.11 12.0 3.2 0.14 11.6 3.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SDA1 PF05285.12 OEU10688.1 - 0.12 11.8 19.5 0.15 11.5 19.5 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 OEU10688.1 - 0.14 11.8 5.3 0.17 11.6 5.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BSP_II PF05432.11 OEU10688.1 - 0.63 9.7 25.9 0.81 9.3 25.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hid1 PF12722.7 OEU10688.1 - 1.9 6.5 7.0 2.1 6.4 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.13 OEU10688.1 - 2.9 6.2 12.4 3.7 5.8 12.4 1.1 1 0 0 1 1 1 0 Menin DENN PF02141.21 OEU10689.1 - 3.9e-34 118.2 0.6 8.8e-34 117.1 0.6 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OEU10689.1 - 9.9e-13 48.6 0.6 6.1e-12 46.1 0.5 2.6 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OEU10689.1 - 3.4e-09 36.6 0.3 7.8e-09 35.4 0.3 1.7 1 0 0 1 1 1 1 dDENN domain zf-MYND PF01753.18 OEU10690.1 - 1.2e-05 25.2 13.2 2.3e-05 24.4 13.2 1.5 1 0 0 1 1 1 1 MYND finger DUF3172 PF11371.8 OEU10690.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) SlpA PF03217.14 OEU10690.1 - 0.09 13.4 0.4 0.27 11.8 0.4 1.9 1 0 0 1 1 1 0 Surface later protein A domain NESP55 PF06390.12 OEU10691.1 - 0.0065 16.1 0.9 0.01 15.4 0.9 1.3 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) SR-25 PF10500.9 OEU10691.1 - 0.4 10.3 5.8 1.9 8.0 0.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tudor_RapA PF18337.1 OEU10691.1 - 0.82 9.9 4.1 5.3 7.3 1.6 2.5 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain Caskin-Pro-rich PF16907.5 OEU10691.1 - 8.3 7.0 6.9 3.8 8.1 2.2 2.3 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Aa_trans PF01490.18 OEU10692.1 - 2.1e-54 184.8 32.4 2.5e-54 184.6 32.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU10692.1 - 0.00028 20.0 7.0 0.00028 20.0 7.0 2.6 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family DUF998 PF06197.13 OEU10692.1 - 0.0039 16.8 14.9 0.027 14.1 5.2 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF998) DUF4231 PF14015.6 OEU10692.1 - 0.015 15.7 12.8 0.068 13.7 0.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) Spore_permease PF03845.13 OEU10692.1 - 0.22 10.3 28.1 0.029 13.2 13.2 3.7 3 1 0 3 3 3 0 Spore germination protein EF-hand_5 PF13202.6 OEU10693.1 - 3e-09 36.0 0.3 0.00017 20.9 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OEU10693.1 - 9.6e-09 34.2 6.5 0.00079 18.8 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OEU10693.1 - 2e-08 34.5 0.5 2e-08 34.5 0.5 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU10693.1 - 1.3e-06 27.9 0.1 0.042 13.8 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain ZT_dimer PF16916.5 OEU10693.1 - 0.00032 20.8 2.0 0.00057 20.0 0.2 2.3 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter SPARC_Ca_bdg PF10591.9 OEU10693.1 - 0.017 15.4 0.4 0.052 13.9 0.3 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LptE PF04390.12 OEU10693.1 - 0.032 14.9 3.3 0.92 10.2 0.8 2.5 2 0 0 2 2 2 0 Lipopolysaccharide-assembly FDX-ACB PF03147.14 OEU10693.1 - 0.039 14.4 0.5 0.11 12.9 0.5 1.7 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain EF-hand_8 PF13833.6 OEU10693.1 - 0.35 10.7 8.5 0.11 12.4 0.7 3.1 2 1 1 3 3 3 0 EF-hand domain pair Snf7 PF03357.21 OEU10693.1 - 3.1 7.3 12.3 0.82 9.3 5.7 2.6 3 0 0 3 3 3 0 Snf7 DOPA_dioxygen PF08883.11 OEU10694.1 - 7.9e-25 87.1 0.2 1.2e-24 86.6 0.2 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF4825 PF16107.5 OEU10694.1 - 0.18 11.9 0.1 0.28 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) ABC_tran PF00005.27 OEU10695.1 - 6.2e-37 127.2 3.5 7.4e-13 49.2 0.2 4.3 2 2 1 3 3 3 3 ABC transporter ABC_tran_Xtn PF12848.7 OEU10695.1 - 2.4e-13 49.9 1.1 2.7e-10 40.1 0.2 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU10695.1 - 7.6e-13 48.9 6.3 0.0032 17.3 0.1 4.5 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU10695.1 - 9.7e-09 35.0 4.1 0.19 11.1 0.0 4.4 3 1 2 5 5 5 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU10695.1 - 2.5e-07 30.8 0.2 0.0026 17.8 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OEU10695.1 - 3e-07 30.1 0.9 0.0075 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU10695.1 - 3e-06 27.9 10.2 0.0014 19.2 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 OEU10695.1 - 5.8e-06 26.4 0.3 0.06 13.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OEU10695.1 - 6.9e-06 26.3 0.0 0.026 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 OEU10695.1 - 1e-05 25.2 3.3 0.0011 18.5 0.4 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OEU10695.1 - 1.4e-05 25.0 0.8 0.0018 18.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 OEU10695.1 - 3e-05 23.3 0.1 0.09 11.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Dynamin_N PF00350.23 OEU10695.1 - 7.8e-05 22.8 6.0 0.0003 20.9 0.2 2.7 3 0 0 3 3 2 1 Dynamin family AAA_22 PF13401.6 OEU10695.1 - 0.0001 22.6 2.2 0.093 13.0 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU10695.1 - 0.00019 22.0 0.1 0.15 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OEU10695.1 - 0.00021 20.4 3.7 0.36 9.8 0.0 3.0 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 OEU10695.1 - 0.00022 21.1 0.1 0.37 10.4 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OEU10695.1 - 0.00066 19.4 0.0 0.89 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OEU10695.1 - 0.0015 18.9 0.4 0.22 11.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 OEU10695.1 - 0.0051 16.6 0.6 4.5 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 OEU10695.1 - 0.0066 16.4 0.2 1.2 9.0 0.0 2.9 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_27 PF13514.6 OEU10695.1 - 0.0076 15.9 0.1 0.29 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 OEU10695.1 - 0.016 15.4 0.8 2.4 8.4 0.1 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 OEU10695.1 - 0.016 14.1 0.2 1.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_17 PF13207.6 OEU10695.1 - 0.017 15.5 1.1 7.4 7.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 OEU10695.1 - 0.031 13.3 0.9 1.2 8.2 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_28 PF13521.6 OEU10695.1 - 0.037 14.3 0.1 20 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 OEU10695.1 - 0.04 13.2 0.3 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 OEU10695.1 - 0.053 13.9 0.1 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OEU10695.1 - 0.054 13.9 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OEU10695.1 - 0.056 13.7 1.3 33 4.8 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 OEU10695.1 - 0.068 12.9 0.1 8 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 OEU10695.1 - 0.076 12.2 0.3 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_13 PF13166.6 OEU10695.1 - 0.081 11.6 0.1 7.5 5.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 OEU10695.1 - 0.081 12.4 0.1 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 OEU10695.1 - 0.1 12.5 0.8 4.5 7.2 0.0 2.9 3 0 0 3 3 2 0 NTPase FtsK_SpoIIIE PF01580.18 OEU10695.1 - 0.1 11.9 0.4 4.5 6.6 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 OEU10695.1 - 0.13 11.5 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Septin DUF4242 PF14026.6 OEU10695.1 - 0.16 12.2 0.1 0.63 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) MobB PF03205.14 OEU10695.1 - 0.19 11.6 0.4 22 4.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 OEU10695.1 - 0.2 11.3 1.5 15 5.2 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 OEU10695.1 - 0.27 10.4 0.8 11 5.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 OEU10695.1 - 0.28 11.1 3.4 12 5.8 0.1 2.6 3 0 0 3 3 2 0 NACHT domain ABC_ATPase PF09818.9 OEU10695.1 - 0.46 9.2 1.9 11 4.7 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 OEU10695.1 - 3.7 7.6 7.7 63 3.5 0.1 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain Peptidase_C97 PF05903.14 OEU10696.1 - 1.4e-13 50.9 0.1 3.4e-13 49.7 0.1 1.7 1 1 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_M3_N PF08439.10 OEU10696.1 - 0.0011 19.2 0.1 1.8 8.9 0.0 2.3 2 0 0 2 2 2 2 Oligopeptidase F LRAT PF04970.13 OEU10696.1 - 0.047 14.0 0.2 3.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF2462 PF09495.10 OEU10699.1 - 0.01 16.6 11.9 0.01 16.6 11.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) RNA_pol_N PF01194.17 OEU10700.1 - 7.1e-33 112.7 0.6 8.2e-33 112.5 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 OEU10700.1 - 0.057 13.7 0.5 0.1 12.9 0.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) HRDC PF00570.23 OEU10701.1 - 0.0043 17.0 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 HRDC domain CALCOCO1 PF07888.11 OEU10703.1 - 2.6 6.8 48.0 0.68 8.7 29.3 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-RVT PF13966.6 OEU10704.1 - 0.019 15.7 1.2 0.069 13.9 1.2 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Cas_NE0113 PF09623.10 OEU10704.1 - 0.03 14.0 0.1 0.081 12.6 0.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) RVT_1 PF00078.27 OEU10705.1 - 1.1e-06 28.3 0.0 3.9e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_ribbon_2 PF12674.7 OEU10705.1 - 1.4 9.7 3.6 52 4.6 0.2 3.2 3 0 0 3 3 3 0 Putative zinc ribbon domain LMWPc PF01451.21 OEU10706.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase Mito_carr PF00153.27 OEU10708.1 - 3.7e-62 206.3 4.8 8.8e-24 83.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OEU10708.1 - 0.052 12.7 6.9 0.52 9.4 1.4 2.9 1 1 0 2 2 2 0 Gammaproteobacterial serine protease YtxH PF12732.7 OEU10708.1 - 4 8.0 4.9 9.4 6.9 0.2 3.1 4 0 0 4 4 4 0 YtxH-like protein Aminotran_4 PF01063.19 OEU10709.1 - 0.0005 20.0 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV TrkA_N PF02254.18 OEU10710.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OEU10710.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PC-Esterase PF13839.6 OEU10712.1 - 0.0097 15.7 4.2 0.034 13.9 3.7 2.0 1 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Hydrolase_4 PF12146.8 OEU10713.1 - 1.3e-07 31.2 0.0 0.0099 15.2 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU10713.1 - 3.9e-06 26.7 0.0 0.053 13.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU10713.1 - 7e-06 25.7 0.0 0.00061 19.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF818 PF05677.12 OEU10713.1 - 3.7e-05 22.9 0.1 5.3e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) LIP PF03583.14 OEU10713.1 - 0.0045 16.4 0.0 0.91 8.8 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_2 PF02230.16 OEU10713.1 - 0.0081 16.0 0.0 0.055 13.3 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OEU10713.1 - 0.018 15.6 0.0 0.28 11.8 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 OEU10713.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 OEU10713.1 - 0.046 13.6 0.0 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 OEU10714.1 - 6e-39 134.0 0.1 1.2e-38 133.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU10714.1 - 3.7e-13 49.7 0.0 8.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU10714.1 - 2.3e-12 47.3 0.5 4.5e-08 33.5 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU10714.1 - 4.3e-09 36.0 0.4 0.00028 20.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU10714.1 - 0.0001 21.2 0.9 0.0072 15.1 0.5 2.8 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 OEU10714.1 - 0.0035 16.5 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OEU10714.1 - 0.0071 15.8 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OEU10714.1 - 0.0086 16.0 0.4 0.075 12.9 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 OEU10714.1 - 0.01 15.9 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GIDA PF01134.22 OEU10714.1 - 0.02 14.0 1.4 0.059 12.4 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 OEU10714.1 - 0.023 14.3 0.6 0.16 11.5 0.1 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OEU10714.1 - 0.033 13.5 1.7 0.47 9.7 0.2 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OEU10714.1 - 0.039 13.0 0.2 0.059 12.4 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4262 PF14081.6 OEU10714.1 - 0.09 13.0 0.0 0.95 9.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4262) NAD_binding_8 PF13450.6 OEU10714.1 - 0.12 12.7 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU10714.1 - 0.12 12.3 0.5 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OEU10714.1 - 3.2 6.7 5.5 0.82 8.7 1.4 2.0 2 0 0 2 2 2 0 FAD binding domain MFS_5 PF05631.14 OEU10715.1 - 5.6e-61 206.4 1.5 8.9e-61 205.8 1.5 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OEU10715.1 - 2.8e-21 75.8 23.7 2.8e-21 75.8 23.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TCRP1 PF14944.6 OEU10715.1 - 0.091 12.7 0.8 0.18 11.8 0.8 1.5 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 N_Asn_amidohyd PF14736.6 OEU10717.1 - 2.8e-12 46.4 0.4 3.7e-12 46.0 0.4 1.3 1 1 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase DUF588 PF04535.12 OEU10718.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) UL42 PF17638.2 OEU10721.1 - 0.78 9.7 7.9 2.3 8.2 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 DUF547 PF04784.14 OEU10722.1 - 7.3e-16 58.3 0.0 2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Pex24p PF06398.11 OEU10722.1 - 0.08 11.9 0.8 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin PCP_red PF08369.10 OEU10723.1 - 0.0024 18.1 0.1 0.0037 17.4 0.1 1.3 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit TPD PF14811.6 OEU10723.1 - 0.063 13.1 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Mito_carr PF00153.27 OEU10724.1 - 2.4e-31 107.5 6.9 4.4e-10 39.3 0.4 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein V4R PF02830.18 OEU10724.1 - 0.0025 17.8 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 V4R domain DUF2967 PF11179.8 OEU10724.1 - 0.33 9.0 4.8 0.042 12.0 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) DUF1348 PF07080.11 OEU10725.1 - 4.9e-62 207.6 2.6 5.7e-62 207.4 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OEU10725.1 - 5.9e-05 23.7 0.1 7.8e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain zf-RING_2 PF13639.6 OEU10727.1 - 5.5e-09 36.2 12.6 7.9e-08 32.5 4.2 2.9 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 OEU10727.1 - 2.6e-08 33.6 0.4 7e-08 32.2 0.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU10727.1 - 3.1e-08 33.2 4.0 0.00011 21.8 0.2 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-rbx1 PF12678.7 OEU10727.1 - 1e-07 32.1 6.9 1e-07 32.1 6.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU10727.1 - 2.8e-06 27.1 3.0 2.8e-06 27.1 3.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU10727.1 - 0.00011 22.2 2.3 0.0003 20.7 1.3 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU10727.1 - 0.00014 21.7 7.9 0.00026 20.9 5.8 2.2 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OEU10727.1 - 0.00015 21.3 0.8 0.00015 21.3 0.8 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU10727.1 - 0.00043 20.1 1.2 0.00043 20.1 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU10727.1 - 0.00068 19.4 1.5 0.00068 19.4 1.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zinc_ribbon_16 PF17034.5 OEU10727.1 - 0.0032 17.7 2.3 0.0051 17.0 2.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon like family zf-C3H2C3 PF17122.5 OEU10727.1 - 0.0092 16.0 1.7 0.0092 16.0 1.7 2.7 3 0 0 3 3 3 1 Zinc-finger zf-ANAPC11 PF12861.7 OEU10727.1 - 0.016 15.2 6.9 0.16 12.0 7.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OEU10727.1 - 0.56 10.4 9.4 16 5.7 7.7 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OEU10727.1 - 1.4 9.1 5.8 0.99 9.6 1.4 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OEU10727.1 - 7.9 6.7 10.1 0.94 9.7 1.6 2.9 2 1 1 3 3 3 0 RING-variant domain HTH_psq PF05225.16 OEU10728.1 - 0.0031 17.2 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 OEU10728.1 - 0.05 13.7 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PUMA PF15826.5 OEU10728.1 - 0.077 13.2 1.8 0.14 12.3 1.8 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis HTH_23 PF13384.6 OEU10728.1 - 0.11 12.3 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Pkinase PF00069.25 OEU10729.1 - 7.4e-64 215.7 0.1 9.2e-64 215.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10729.1 - 5.7e-27 94.6 0.0 7.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU10729.1 - 9.2e-05 21.9 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OEU10730.1 - 1.4e-69 234.5 0.0 1.5e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10730.1 - 2e-31 109.3 0.0 2.3e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU10730.1 - 0.0031 16.3 0.0 0.0085 14.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU10730.1 - 0.0049 16.2 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU10730.1 - 0.011 15.0 0.0 0.058 12.7 0.0 2.0 2 1 0 2 2 2 0 Kinase-like ELYS-bb PF16687.5 OEU10731.1 - 0.023 13.3 0.0 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Flu_B_NS1 PF02942.14 OEU10731.1 - 0.046 12.8 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) OSTMP1 PF09777.9 OEU10731.1 - 0.057 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TPR_1 PF00515.28 OEU10732.1 - 3.6e-05 23.4 0.0 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10732.1 - 0.00058 19.8 0.0 0.2 11.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat PhaP_Bmeg PF09602.10 OEU10732.1 - 0.027 14.4 0.2 0.056 13.4 0.2 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TPR_12 PF13424.6 OEU10732.1 - 0.037 14.3 0.0 6.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LCM PF04072.14 OEU10733.1 - 9.3e-09 35.5 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase NAD_binding_1 PF00175.21 OEU10734.1 - 0.00077 20.1 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OEU10734.1 - 0.00091 19.4 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4834 PF16118.5 OEU10735.1 - 0.016 16.1 0.3 0.47 11.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) HMA PF00403.26 OEU10736.1 - 0.004 17.6 0.6 0.012 16.1 0.1 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Phostensin PF13914.6 OEU10738.1 - 0.0071 17.0 5.8 0.0073 16.9 0.1 2.4 1 1 0 2 2 2 1 Phostensin PP1-binding and SH3-binding region Mucin PF01456.17 OEU10738.1 - 0.37 10.8 17.1 0.54 10.2 3.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4834 PF16118.5 OEU10738.1 - 1.7 9.7 8.8 5.5 8.0 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Mito_carr PF00153.27 OEU10741.1 - 2.4e-61 203.7 0.1 7.6e-23 80.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 60KD_IMP PF02096.20 OEU10741.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 60Kd inner membrane protein ESM4 PF15952.5 OEU10741.1 - 0.17 12.3 11.2 0.43 11.0 11.2 1.6 1 0 0 1 1 1 0 Enhancer of split M4 family TFIIA PF03153.13 OEU10741.1 - 0.4 10.6 11.9 0.68 9.9 11.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OEU10741.1 - 0.53 9.0 4.6 0.72 8.6 4.6 1.3 1 0 0 1 1 1 0 Presenilin DUF2070 PF09843.9 OEU10744.1 - 0.18 10.1 0.1 0.22 9.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lipase_3 PF01764.25 OEU10745.1 - 3.7e-11 43.1 0.0 1.2e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OEU10745.1 - 0.016 14.5 0.0 0.35 10.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2391 PF09622.10 OEU10745.1 - 0.52 9.6 2.4 1 8.6 2.4 1.4 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Herpes_LMP1 PF05297.11 OEU10746.1 - 0.011 14.9 9.2 0.022 14.0 9.2 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DnaJ PF00226.31 OEU10746.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain Nop14 PF04147.12 OEU10746.1 - 0.61 8.2 6.4 0.93 7.6 6.4 1.2 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_jaz PF12171.8 OEU10747.1 - 4.4e-06 26.8 3.8 1.3e-05 25.4 3.8 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OEU10747.1 - 1.8e-05 25.0 4.1 4.3e-05 23.8 4.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OEU10747.1 - 0.09 13.7 1.4 0.36 11.8 1.4 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 OEU10747.1 - 0.37 10.9 4.4 1.3 9.2 4.4 1.9 1 0 0 1 1 1 0 DBF zinc finger GST_N_2 PF13409.6 OEU10750.1 - 1.7e-12 47.4 0.1 8.2e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU10750.1 - 1.5e-05 25.0 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU10750.1 - 0.0038 17.4 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF727 PF05303.12 OEU10750.1 - 0.054 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF727) GST_N_3 PF13417.6 OEU10750.1 - 0.094 13.1 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain TspO_MBR PF03073.15 OEU10752.1 - 2.7e-13 50.1 2.1 3.5e-13 49.8 2.1 1.1 1 0 0 1 1 1 1 TspO/MBR family SUIM_assoc PF16619.5 OEU10754.1 - 4.9e-06 26.5 5.5 0.001 19.1 1.0 3.0 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 MlaC PF05494.12 OEU10754.1 - 0.035 13.9 4.4 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 MlaC protein Pex14_N PF04695.13 OEU10754.1 - 0.16 12.6 5.0 0.22 12.2 2.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.8 OEU10754.1 - 0.48 9.6 8.0 2.2 7.4 4.5 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GN3L_Grn1 PF08701.11 OEU10754.1 - 1 9.5 6.2 1.2 9.3 2.6 2.4 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Gal-bind_lectin PF00337.22 OEU10755.1 - 1.2e-09 37.8 0.0 2.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 OEU10755.1 - 0.00022 21.0 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 OEU10756.1 - 0.072 11.6 8.8 0.14 10.7 8.8 1.4 1 0 0 1 1 1 0 Macoilin family bZIP_2 PF07716.15 OEU10757.1 - 0.016 15.3 7.7 0.03 14.4 7.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 OEU10757.1 - 0.018 15.5 2.9 0.023 15.2 2.9 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Spore_coat_CotO PF14153.6 OEU10760.1 - 0.02 14.9 3.3 0.026 14.5 3.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO BAF1_ABF1 PF04684.13 OEU10760.1 - 0.037 13.1 5.6 0.033 13.3 5.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SDA1 PF05285.12 OEU10760.1 - 0.45 9.9 31.2 0.5 9.7 31.2 1.1 1 0 0 1 1 1 0 SDA1 RNA_polI_A34 PF08208.11 OEU10760.1 - 3.2 7.8 14.8 4.3 7.4 14.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3050 PF11251.8 OEU10761.1 - 0.027 14.1 0.1 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) Peptidase_M50B PF13398.6 OEU10762.1 - 1e-40 139.5 18.0 1.3e-40 139.2 18.0 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF3267 PF11667.8 OEU10762.1 - 0.099 12.9 0.2 0.099 12.9 0.2 3.5 2 1 2 4 4 4 0 Putative zincin peptidase CDC37_C PF08564.10 OEU10763.1 - 0.011 15.9 5.9 0.77 9.9 0.1 2.6 2 0 0 2 2 2 0 Cdc37 C terminal domain Hydrolase_4 PF12146.8 OEU10763.1 - 0.06 12.6 0.7 0.67 9.2 0.3 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Chordopox_E11 PF06138.12 OEU10763.1 - 0.082 13.2 0.2 9.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus E11 protein DUF4056 PF13265.6 OEU10763.1 - 0.1 11.9 3.8 3.5 6.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4056) PNISR PF15996.5 OEU10763.1 - 1.3 9.3 21.2 4.9 7.4 3.1 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FKBP_C PF00254.28 OEU10764.1 - 5.7e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3048_C PF17479.2 OEU10764.1 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain DUF2721 PF11026.8 OEU10766.1 - 9.7e-05 22.3 0.9 0.00024 21.0 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2721) Connexin PF00029.19 OEU10766.1 - 0.00021 21.2 0.2 0.0007 19.4 0.0 1.7 1 1 1 2 2 2 1 Connexin LMBR1 PF04791.16 OEU10766.1 - 0.0003 19.8 0.0 0.00048 19.2 0.0 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Orf78 PF06024.12 OEU10766.1 - 0.00059 20.1 0.2 0.00059 20.1 0.2 2.1 2 0 0 2 2 2 1 Orf78 (ac78) Claudin_2 PF13903.6 OEU10766.1 - 0.00073 19.3 0.3 0.00073 19.3 0.3 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Spt20 PF12090.8 OEU10766.1 - 0.00092 18.9 0.3 0.0014 18.3 0.3 1.2 1 0 0 1 1 1 1 Spt20 family Nucleoside_tran PF01733.18 OEU10766.1 - 0.0013 18.2 0.1 0.0036 16.7 0.1 1.6 1 1 1 2 2 2 1 Nucleoside transporter Otopetrin PF03189.13 OEU10766.1 - 0.0013 17.6 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 Otopetrin DUF2722 PF10846.8 OEU10766.1 - 0.0015 17.6 0.3 0.0018 17.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) PMP22_Claudin PF00822.20 OEU10766.1 - 0.0028 17.6 0.6 0.0028 17.6 0.6 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family PBP1_TM PF14812.6 OEU10766.1 - 0.0041 17.4 0.6 0.008 16.5 0.6 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1282 PF06930.12 OEU10766.1 - 0.023 14.5 0.6 0.023 14.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) LRRC37AB_C PF14914.6 OEU10766.1 - 0.041 13.8 0.2 0.041 13.8 0.2 1.5 2 0 0 2 2 1 0 LRRC37A/B like protein 1 C-terminal domain Secretin_N_2 PF07655.13 OEU10766.1 - 0.071 13.7 10.4 1.7 9.3 0.6 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF2207 PF09972.9 OEU10766.1 - 0.078 11.7 0.2 0.078 11.7 0.2 2.5 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) TMEM51 PF15345.6 OEU10766.1 - 0.12 12.2 0.2 4.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 GOLD_2 PF13897.6 OEU10766.1 - 0.17 12.4 0.4 3.2 8.3 0.1 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Sigma_reg_N PF13800.6 OEU10766.1 - 5.9 7.3 11.4 0.81 10.0 2.2 2.7 3 0 0 3 3 2 0 Sigma factor regulator N-terminal DUF3139 PF11337.8 OEU10766.1 - 7.9 7.2 6.0 52 4.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Wtap PF17098.5 OEU10767.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Sacchrp_dh_NADP PF03435.18 OEU10768.1 - 0.0088 16.3 0.5 0.62 10.3 0.0 2.8 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain GtrA PF04138.14 OEU10771.1 - 0.063 13.5 3.9 0.073 13.3 0.6 2.2 2 0 0 2 2 2 0 GtrA-like protein UPF0239 PF06783.11 OEU10771.1 - 0.074 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF2207 PF09972.9 OEU10771.1 - 1.5 7.5 2.8 5.9 5.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NUDIX PF00293.28 OEU10772.1 - 6.8e-16 58.5 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 OEU10772.1 - 8e-14 51.4 0.3 2.1e-13 50.1 0.1 1.8 2 0 0 2 2 2 1 Nudix hydrolase domain COMM_domain PF07258.14 OEU10772.1 - 0.021 14.9 0.1 0.081 13.1 0.1 1.9 2 0 0 2 2 2 0 COMM domain Fasciclin PF02469.22 OEU10773.1 - 6.4e-10 39.3 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain UL42 PF17638.2 OEU10774.1 - 0.77 9.7 7.9 2.3 8.2 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 PDE4_UCR PF18100.1 OEU10776.1 - 0.39 11.4 3.7 0.26 11.9 0.4 2.1 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) MOZ_SAS PF01853.18 OEU10777.1 - 4.7e-80 267.5 0.4 6.4e-80 267.0 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OEU10777.1 - 9.4e-14 50.8 0.0 2.3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 OEU10777.1 - 0.0026 18.1 0.0 0.006 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU10777.1 - 0.036 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family bZIP_1 PF00170.21 OEU10778.1 - 3.4e-12 46.3 5.9 8.3e-12 45.0 5.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU10778.1 - 2.2e-09 37.3 7.6 5.4e-09 36.0 7.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU10778.1 - 0.018 15.5 2.2 0.018 15.5 2.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor YabA PF06156.13 OEU10778.1 - 0.098 13.3 0.1 0.098 13.3 0.1 2.3 2 1 0 2 2 2 0 Initiation control protein YabA PP-binding_2 PF14573.6 OEU10778.1 - 0.099 12.9 0.5 0.23 11.7 0.5 1.5 1 0 0 1 1 1 0 Acyl-carrier HA PF03457.14 OEU10779.1 - 4.4e-54 180.7 5.5 4.1e-18 65.5 0.2 3.0 3 0 0 3 3 3 3 Helicase associated domain Imm64 PF15600.6 OEU10779.1 - 0.04 13.6 0.7 0.96 9.1 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 64 LPD22 PF18834.1 OEU10779.1 - 0.074 13.3 0.2 33 4.8 0.0 3.0 1 1 2 3 3 3 0 Large polyvalent protein associated domain 22 Glyco_trans_4_5 PF16994.5 OEU10779.1 - 0.38 10.3 5.5 0.52 9.9 0.9 2.5 1 1 2 3 3 3 0 Glycosyl-transferase family 4 Glyco_transf_8 PF01501.20 OEU10780.1 - 3.7e-08 33.2 8.9 0.01 15.4 0.0 4.1 5 0 0 5 5 5 3 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OEU10780.1 - 1.1e-07 31.5 2.4 0.00044 19.7 0.0 2.8 3 0 0 3 3 3 2 Mannosyltransferase putative Ig_5 PF16681.5 OEU10781.1 - 0.066 13.6 0.1 0.29 11.5 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ribosomal_S26e PF01283.19 OEU10782.1 - 4e-48 162.3 5.0 4.3e-48 162.2 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e RTC PF01137.21 OEU10783.1 - 5.6e-64 215.4 2.0 1e-63 214.5 2.0 1.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OEU10783.1 - 1.1e-12 48.3 0.5 4.4e-12 46.4 0.5 2.0 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SpaA PF17802.1 OEU10783.1 - 3.3 8.1 5.9 1.5 9.2 1.5 2.3 2 0 0 2 2 2 0 Prealbumin-like fold domain DEAD PF00270.29 OEU10784.1 - 4.7e-47 160.0 0.0 6e-46 156.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU10784.1 - 1.7e-31 108.8 0.0 3e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU10784.1 - 2.7e-05 23.5 0.0 4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OEU10784.1 - 0.0026 17.8 0.0 0.0092 16.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 OEU10784.1 - 0.0038 17.4 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_22 PF13401.6 OEU10784.1 - 0.027 14.7 1.0 0.54 10.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain YoqO PF14037.6 OEU10785.1 - 0.00062 20.3 8.9 0.15 12.6 2.0 2.4 2 0 0 2 2 2 2 YoqO-like protein FecCD PF01032.18 OEU10785.1 - 0.011 14.8 2.9 0.011 14.8 2.9 2.3 2 1 1 3 3 3 0 FecCD transport family TMCCDC2 PF15844.5 OEU10785.1 - 0.15 12.0 2.7 2.8 7.9 0.8 2.3 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 DUF4131 PF13567.6 OEU10785.1 - 0.18 11.5 7.8 0.58 9.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_60s PF00428.19 OEU10786.1 - 5.9e-17 62.0 5.0 7e-17 61.8 5.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein 2OG-FeII_Oxy_3 PF13640.6 OEU10787.1 - 4.1e-14 53.2 0.0 6.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU10787.1 - 0.039 14.4 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Phage_int_SAM_3 PF14659.6 OEU10788.1 - 0.017 15.4 0.3 0.017 15.4 0.3 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF5511 PF17630.2 OEU10788.1 - 0.052 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5511) Snf7 PF03357.21 OEU10789.1 - 8.1e-21 74.4 24.8 1.1e-20 73.9 24.8 1.3 1 0 0 1 1 1 1 Snf7 Ferritin PF00210.24 OEU10789.1 - 0.011 15.7 0.8 0.011 15.7 0.8 2.3 2 1 0 2 2 2 0 Ferritin-like domain SRC-1 PF08832.10 OEU10789.1 - 0.19 12.8 5.9 0.72 10.9 0.9 3.2 2 1 0 2 2 2 0 Steroid receptor coactivator YlqD PF11068.8 OEU10789.1 - 1 9.8 20.9 3.6 8.0 5.2 2.6 1 1 1 2 2 2 0 YlqD protein PCRF PF03462.18 OEU10789.1 - 3.7 7.4 24.0 0.05 13.5 6.6 2.3 1 1 1 2 2 2 0 PCRF domain MAT1 PF06391.13 OEU10789.1 - 7.1 6.4 20.9 6 6.6 9.2 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 SR-25 PF10500.9 OEU10790.1 - 0.32 10.6 9.7 5.4 6.6 5.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glucosamine_iso PF01182.20 OEU10791.1 - 2.1e-28 99.7 0.1 4.1e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Methyltransf_34 PF11312.8 OEU10792.1 - 1.8e-06 27.4 0.0 3.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF3446 PF11928.8 OEU10792.1 - 2.2 8.7 21.8 20 5.6 0.3 4.5 4 0 0 4 4 4 0 Early growth response N-terminal domain Dicty_REP PF05086.12 OEU10792.1 - 5.8 4.8 11.4 0.064 11.2 3.3 1.7 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF2868 PF11067.8 OEU10793.1 - 0.51 9.8 7.1 1 8.8 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) RskA PF10099.9 OEU10793.1 - 1.1 9.6 14.1 2.1 8.6 14.1 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AAA_17 PF13207.6 OEU10793.1 - 7.9 6.9 7.6 31 5.0 0.2 3.5 3 0 0 3 3 3 0 AAA domain DUF5312 PF17239.2 OEU10795.1 - 0.008 14.6 0.2 0.011 14.1 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5312) DUF1079 PF06435.11 OEU10795.1 - 0.062 13.5 2.3 0.086 13.1 0.1 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) DUF4262 PF14081.6 OEU10795.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) SPAN-X PF07458.12 OEU10795.1 - 3.3 8.2 14.4 1.1 9.7 9.3 2.1 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome CRAL_TRIO_N PF03765.15 OEU10796.1 - 0.0024 18.0 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Sigma_reg_C PF13791.6 OEU10796.1 - 0.0072 16.5 5.3 0.38 11.0 1.7 2.5 2 0 0 2 2 2 2 Sigma factor regulator C-terminal ORC_WH_C PF18137.1 OEU10796.1 - 3.1 7.9 8.1 0.39 10.8 1.2 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF1840 PF08895.11 OEU10796.1 - 4.9 7.5 5.6 1.7 9.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Titin_Ig-rpts PF06582.12 OEU10798.1 - 0.18 11.7 0.1 21 5.2 0.0 2.4 2 0 0 2 2 2 0 Titin repeat DUF2637 PF10935.8 OEU10801.1 - 0.16 11.9 0.2 0.32 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Dsh_C PF12316.8 OEU10803.1 - 5.1 7.5 10.6 8.3 6.8 10.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GST_N_2 PF13409.6 OEU10804.1 - 5.7e-14 52.2 0.0 1.4e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU10804.1 - 3.4e-10 40.2 0.0 8.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU10804.1 - 0.0032 17.6 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU10804.1 - 0.0073 16.6 0.2 0.027 14.8 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CcdA PF07362.12 OEU10804.1 - 0.016 15.6 0.0 10 6.7 0.0 3.0 2 1 1 3 3 3 0 Post-segregation antitoxin CcdA Fasciclin PF02469.22 OEU10805.1 - 3.6e-31 108.0 0.0 4.1e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 OEU10806.1 - 7.2e-31 107.1 0.0 8e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain NAD_binding_10 PF13460.6 OEU10807.1 - 1.3e-13 51.3 0.1 2.3e-13 50.4 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU10807.1 - 1.8e-12 47.3 0.1 2.8e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OEU10807.1 - 1.1e-10 41.4 0.0 2.4e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU10807.1 - 0.00011 21.4 0.0 0.00027 20.0 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OEU10807.1 - 0.00028 20.1 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OEU10807.1 - 0.0049 16.0 0.0 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain DUF296 PF03479.15 OEU10807.1 - 0.042 14.2 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain KR PF08659.10 OEU10807.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Glyco_hydro_17 PF00332.18 OEU10808.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Peptidase_M23 PF01551.22 OEU10810.1 - 1.5e-13 50.8 0.6 7.1e-06 26.1 0.0 3.3 1 1 0 3 3 3 2 Peptidase family M23 ADH_zinc_N PF00107.26 OEU10811.1 - 2.5e-08 34.0 0.1 4.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU10811.1 - 0.00081 19.3 0.0 0.0078 16.1 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DJ-1_PfpI PF01965.24 OEU10811.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 DJ-1/PfpI family ADH_N_2 PF16884.5 OEU10811.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase EIIBC-GUT_N PF03612.14 OEU10811.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Bunya_nucleocap PF00952.17 OEU10811.1 - 0.17 11.9 0.1 0.28 11.2 0.1 1.2 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein Trypan_PARP PF05887.11 OEU10813.1 - 0.097 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 OEU10813.1 - 7.5 6.1 12.8 39 3.7 12.7 1.9 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) CCER1 PF15482.6 OEU10815.1 - 0.0004 20.3 0.3 0.00099 19.1 0.3 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 CDC45 PF02724.14 OEU10815.1 - 0.0026 16.1 12.3 0.0026 16.1 12.3 2.2 2 0 0 2 2 2 1 CDC45-like protein RRN3 PF05327.11 OEU10815.1 - 0.0035 16.0 12.3 0.0035 16.0 12.3 1.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Pex14_N PF04695.13 OEU10815.1 - 0.024 15.3 7.2 2.2 8.9 0.0 4.0 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.15 OEU10815.1 - 0.027 13.4 1.0 0.26 10.2 1.1 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Sec62 PF03839.16 OEU10815.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.7 4 0 0 4 4 4 0 Translocation protein Sec62 SID-1_RNA_chan PF13965.6 OEU10815.1 - 0.14 10.6 0.6 0.3 9.4 0.6 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ETRAMP PF09716.10 OEU10815.1 - 0.23 11.6 0.8 2.8 8.1 0.0 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Neur_chan_memb PF02932.16 OEU10815.1 - 0.63 10.1 0.0 0.63 10.1 0.0 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 OEU10815.1 - 1.4 9.0 13.3 0.087 13.0 1.1 2.7 2 1 0 2 2 2 0 DDHD domain Astro_capsid_p PF12226.8 OEU10815.1 - 2.4 7.2 19.5 4.9 6.2 19.5 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF1980 PF09323.10 OEU10815.1 - 4.2 7.2 4.6 1.4 8.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Nop14 PF04147.12 OEU10815.1 - 7.1 4.7 34.8 0.82 7.8 28.1 2.1 2 0 0 2 2 2 0 Nop14-like family DUF913 PF06025.12 OEU10815.1 - 8.4 5.3 15.5 0.03 13.3 5.5 2.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 OEU10815.1 - 9.6 5.9 5.9 0.75 9.5 0.5 2.0 2 0 0 2 2 2 0 Connexin DUF778 PF05608.12 OEU10816.1 - 4.6e-32 111.9 0.8 1.7e-15 57.9 0.5 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF778) DEAD PF00270.29 OEU10817.1 - 6.5e-34 117.2 0.1 4.7e-32 111.1 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU10817.1 - 2.8e-23 82.4 0.0 8.6e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU10817.1 - 0.00039 19.7 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OEU10817.1 - 0.00061 19.8 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 OEU10817.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain NAGidase PF07555.13 OEU10817.1 - 0.14 11.5 0.0 18 4.5 0.0 2.3 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase HA PF03457.14 OEU10818.1 - 1.8e-51 172.3 9.8 1.3e-16 60.6 0.3 3.2 3 0 0 3 3 3 3 Helicase associated domain PMR5N PF14416.6 OEU10818.1 - 0.0049 17.2 0.8 3.4 8.0 0.0 3.5 3 0 0 3 3 3 1 PMR5 N terminal Domain IstB_IS21_ATP PF08483.11 OEU10818.1 - 0.015 15.2 0.0 22 5.1 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding N-terminal PspB PF06667.12 OEU10818.1 - 0.026 14.6 0.1 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Phage shock protein B UPF0158 PF03682.13 OEU10818.1 - 0.036 14.1 0.3 6.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) CRAM_rpt PF07016.11 OEU10818.1 - 0.17 11.7 2.5 82 3.2 0.1 3.4 3 0 0 3 3 3 0 Cysteine-rich acidic integral membrane protein precursor DUF5362 PF17319.2 OEU10818.1 - 0.4 10.5 0.4 20 5.1 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Ceramidase PF05875.12 OEU10819.1 - 6e-32 111.1 6.6 1.1e-27 97.2 0.1 2.1 1 1 1 2 2 2 2 Ceramidase PrsW-protease PF13367.6 OEU10819.1 - 0.038 13.4 4.7 0.17 11.4 0.5 2.1 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease DUF755 PF05501.11 OEU10820.1 - 0.0026 18.0 1.9 0.0034 17.6 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Androgen_recep PF02166.16 OEU10820.1 - 0.046 12.6 1.3 0.053 12.4 1.3 1.1 1 0 0 1 1 1 0 Androgen receptor STAS PF01740.21 OEU10821.1 - 5.5e-06 26.0 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Phage_holin_2_2 PF10746.9 OEU10821.1 - 0.0063 16.1 0.3 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 Phage holin T7 family, holin superfamily II SR-25 PF10500.9 OEU10822.1 - 0.013 15.1 4.8 0.018 14.7 4.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_binding_4 PF07993.12 OEU10822.1 - 0.056 12.6 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein CAP_N PF01213.19 OEU10823.1 - 0.036 13.6 0.9 0.059 12.9 0.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CLCA PF08434.11 OEU10823.1 - 0.19 11.0 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal PRIMA1 PF16101.5 OEU10823.1 - 0.51 10.4 5.9 1.2 9.2 5.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 p450 PF00067.22 OEU10824.1 - 1.3e-13 50.6 0.0 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMP2_N PF18590.1 OEU10826.1 - 1.5e-33 115.1 0.0 2.7e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 OEU10826.1 - 1.5e-05 24.8 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 2 Immune Mapped Protein 2 (IMP2) C-terminal domain CDC45 PF02724.14 OEU10826.1 - 0.0019 16.6 12.1 0.0019 16.6 12.1 2.3 2 0 0 2 2 2 1 CDC45-like protein OMP_b-brl PF13505.6 OEU10826.1 - 0.5 10.5 5.5 0.15 12.2 1.5 2.1 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Ribosomal_60s PF00428.19 OEU10826.1 - 5.7 7.6 12.6 0.26 11.9 5.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Aminotran_1_2 PF00155.21 OEU10827.1 - 2.8e-48 164.9 0.1 3.4e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 OEU10827.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III FAM176 PF14851.6 OEU10828.1 - 0.61 9.7 8.2 2.5 7.8 0.1 3.2 3 0 0 3 3 3 0 FAM176 family DUF3464 PF11947.8 OEU10829.1 - 1.1 9.0 3.7 18 5.0 0.7 2.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 cNMP_binding PF00027.29 OEU10830.1 - 0.17 12.0 0.2 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain WD40 PF00400.32 OEU10831.1 - 2.4e-05 25.0 11.2 0.082 13.8 0.2 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat PD40 PF07676.12 OEU10831.1 - 0.0011 18.8 0.1 1.4 9.0 0.1 3.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 OEU10831.1 - 0.0043 17.3 0.0 0.5 10.7 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Zip PF02535.22 OEU10833.1 - 0.0018 17.5 11.7 0.0035 16.6 0.0 2.5 2 1 1 3 3 3 1 ZIP Zinc transporter Fst_toxin PF13955.6 OEU10833.1 - 0.33 10.9 1.0 0.66 10.0 1.0 1.5 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system DUF1057 PF06342.12 OEU10835.1 - 0.076 12.0 1.1 4.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) AFG1_ATPase PF03969.16 OEU10838.1 - 4e-67 226.7 1.1 3.9e-59 200.4 0.3 2.6 1 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OEU10838.1 - 0.00016 22.1 0.1 0.00079 19.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU10838.1 - 0.004 17.4 0.0 0.0085 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OEU10838.1 - 0.043 13.3 3.3 0.091 12.3 3.3 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RNA_helicase PF00910.22 OEU10838.1 - 0.051 14.0 1.3 0.14 12.6 0.1 2.4 3 1 0 3 3 3 0 RNA helicase DUF4834 PF16118.5 OEU10838.1 - 8.6 7.4 6.7 1.6 9.8 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RVT_2 PF07727.14 OEU10841.1 - 0.0016 18.1 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhyH PF05721.13 OEU10843.1 - 1.6e-33 116.8 0.0 2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OEU10843.1 - 0.0013 19.1 0.0 0.0037 17.7 0.0 1.7 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase FAM176 PF14851.6 OEU10843.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Col_cuticle_N PF01484.17 OEU10844.1 - 0.4 10.8 0.1 0.4 10.8 0.1 3.8 3 2 1 4 4 4 0 Nematode cuticle collagen N-terminal domain PRA1 PF03208.19 OEU10844.1 - 4.6 6.9 13.3 0.23 11.1 6.3 1.9 1 1 1 2 2 2 0 PRA1 family protein BRI3BP PF14965.6 OEU10844.1 - 5.1 6.6 11.2 7.9 5.9 11.2 1.3 1 1 0 1 1 1 0 Negative regulator of p53/TP53 PPR_2 PF13041.6 OEU10845.1 - 3.4e-47 158.4 28.0 6.4e-11 42.3 0.3 11.3 9 3 2 11 11 11 9 PPR repeat family PPR_1 PF12854.7 OEU10845.1 - 3.8e-43 144.9 21.2 4.7e-07 29.4 0.0 13.1 13 1 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 OEU10845.1 - 2.1e-34 117.4 17.2 2.2e-07 30.9 0.1 9.9 7 3 2 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 OEU10845.1 - 1e-31 107.0 22.6 0.00014 21.9 0.0 14.1 14 3 0 14 14 14 9 PPR repeat PPR_long PF17177.4 OEU10845.1 - 3.2e-20 72.4 0.6 4.3e-05 23.0 0.0 4.6 1 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP DUF4949 PF16307.5 OEU10845.1 - 0.0098 16.0 0.5 4 7.6 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4949) COesterase PF00135.28 OEU10846.1 - 1.7e-104 350.5 1.7 5.7e-89 299.3 0.0 3.5 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 OEU10846.1 - 3.6e-10 40.1 0.0 2.7e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 OEU10847.1 - 9.7e-13 48.0 0.3 2.8e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 OEU10847.1 - 0.15 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Ank_2 PF12796.7 OEU10848.1 - 0.0018 18.8 0.1 0.04 14.5 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) DUF2312 PF10073.9 OEU10848.1 - 0.0051 16.4 0.3 0.015 14.9 0.3 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) TFIIE-A_C PF11521.8 OEU10848.1 - 0.57 10.5 7.5 0.64 10.4 0.3 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha WRNPLPNID PF15017.6 OEU10848.1 - 1.6 9.7 6.4 17 6.4 0.3 3.3 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box AF-4 PF05110.13 OEU10850.1 - 0.096 10.8 17.9 0.11 10.5 17.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1539 PF07560.11 OEU10850.1 - 0.19 11.8 9.6 0.52 10.4 1.1 3.6 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1539) MIT PF04212.18 OEU10851.1 - 0.0017 18.3 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 OEU10851.1 - 0.0092 16.3 0.5 0.5 10.7 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10851.1 - 0.011 15.8 2.1 0.025 14.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU10851.1 - 0.04 14.0 3.0 0.13 12.4 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10851.1 - 0.054 13.3 1.2 0.18 11.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU10851.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 OEU10854.1 - 0.056 13.2 8.9 0.063 13.0 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 OEU10854.1 - 0.15 11.2 12.4 0.18 10.9 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 OEU10854.1 - 7.5 5.0 8.5 9 4.7 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sorting_nexin PF03700.13 OEU10855.1 - 0.2 12.3 2.8 0.24 11.9 2.3 1.5 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain TRAF_BIRC3_bd PF16673.5 OEU10855.1 - 0.2 11.5 4.1 6.6 6.6 1.3 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2263 PF10021.9 OEU10855.1 - 0.81 10.1 6.7 1.1 9.6 6.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) HA PF03457.14 OEU10856.1 - 9.7e-33 112.3 0.7 1.3e-15 57.5 0.1 2.0 2 0 0 2 2 2 2 Helicase associated domain Bax1-I PF01027.20 OEU10858.1 - 0.28 11.0 13.5 0.37 10.6 13.5 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF5336 PF17270.2 OEU10858.1 - 1.3 8.6 12.9 1.6 8.3 12.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4355 PF14265.6 OEU10859.1 - 0.039 14.2 0.8 0.097 12.9 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Activator_LAG-3 PF11498.8 OEU10859.1 - 0.88 8.5 11.3 1.2 8.0 11.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BTB_2 PF02214.22 OEU10860.1 - 3e-08 33.9 0.0 1.2e-07 32.0 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU10860.1 - 0.099 12.7 0.0 0.29 11.2 0.0 1.8 1 1 1 2 2 2 0 BTB/POZ domain GET2 PF08690.10 OEU10860.1 - 2.8 7.5 6.3 4.9 6.7 6.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 PI-PLC-X PF00388.19 OEU10861.1 - 2.5e-46 156.9 0.0 6.2e-46 155.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OEU10861.1 - 4.7e-34 117.2 0.0 9.6e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OEU10861.1 - 6.4e-13 48.9 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 OEU10861.1 - 0.0012 18.6 0.2 3.6 7.8 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain PMBR PF09373.10 OEU10861.1 - 0.078 13.2 0.5 0.88 9.8 0.0 2.8 2 0 0 2 2 2 0 Pseudomurein-binding repeat ECH_1 PF00378.20 OEU10861.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase zf-MYND PF01753.18 OEU10862.1 - 2.4e-06 27.5 14.5 8.3e-06 25.8 14.5 2.1 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 OEU10863.1 - 2.9e-15 55.1 18.6 0.0014 18.6 0.1 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU10863.1 - 8.1e-12 44.4 3.2 5.9e-05 23.0 0.1 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU10863.1 - 4.9e-11 42.0 11.4 0.00011 21.9 0.1 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 OEU10863.1 - 1.3e-08 35.0 15.9 0.18 12.7 0.4 6.6 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU10863.1 - 5.2e-08 32.4 7.2 2.2e-05 24.2 0.8 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU10863.1 - 3.4e-06 27.6 17.6 0.026 15.2 3.0 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU10863.1 - 3.7e-06 27.1 15.4 0.031 14.6 0.3 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU10863.1 - 0.0019 17.8 3.3 4.6 7.0 0.1 5.3 5 1 1 6 6 6 1 TPR repeat TPR_6 PF13174.6 OEU10863.1 - 0.013 16.1 9.0 0.74 10.6 0.2 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU10863.1 - 0.025 14.4 10.2 0.55 10.2 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OEU10863.1 - 0.037 14.2 13.7 7.5 6.8 0.2 4.7 3 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU10863.1 - 0.066 13.7 6.0 17 6.0 0.1 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU10863.1 - 0.39 11.0 16.5 11 6.3 0.7 4.4 1 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Autophagy_N PF03986.13 OEU10864.1 - 7.7e-34 116.6 1.8 7.7e-34 116.6 1.8 2.2 2 1 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OEU10864.1 - 7.6e-17 61.7 2.1 1.3e-16 60.9 2.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OEU10864.1 - 3.1e-13 49.0 4.0 7.8e-13 47.7 4.0 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PGM_PMM_III PF02880.16 OEU10865.1 - 0.23 11.7 0.0 78 3.5 0.0 3.6 4 0 0 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SDA1 PF05285.12 OEU10865.1 - 0.77 9.1 26.9 0.075 12.5 7.7 2.2 2 0 0 2 2 2 0 SDA1 SPX PF03105.19 OEU10865.1 - 3.4 7.5 10.8 4.7 7.0 1.5 2.3 2 0 0 2 2 2 0 SPX domain Chloroa_b-bind PF00504.21 OEU10866.1 - 9.2e-38 130.3 0.0 1.4e-37 129.7 0.0 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein 60KD_IMP PF02096.20 OEU10867.1 - 1.9e-42 145.0 0.0 2.1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2062 PF09835.9 OEU10867.1 - 0.054 13.4 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) 2OG-FeII_Oxy_3 PF13640.6 OEU10868.1 - 9.6e-07 29.6 0.0 2.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily InaF-motif PF15018.6 OEU10868.1 - 6.7 6.7 5.7 0.89 9.5 1.0 2.0 2 0 0 2 2 2 0 TRP-interacting helix DcpS_C PF11969.8 OEU10869.1 - 2.1e-24 86.2 0.1 3.9e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Spb1_C PF07780.12 OEU10870.1 - 8.2e-22 77.9 19.1 1e-21 77.6 19.1 1.1 1 0 0 1 1 1 1 Spb1 C-terminal domain FtsJ PF01728.19 OEU10871.1 - 5.1e-50 170.0 0.1 5.7e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OEU10871.1 - 5.5e-06 26.2 0.2 9.1e-06 25.4 0.2 1.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 OEU10871.1 - 0.021 15.5 0.1 0.045 14.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OEU10871.1 - 0.039 13.8 0.0 0.054 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_5 PF00941.21 OEU10871.1 - 0.17 11.6 0.0 18 5.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase FAD_binding_3 PF01494.19 OEU10872.1 - 0.025 13.8 0.0 0.027 13.7 0.0 1.3 1 1 0 1 1 1 0 FAD binding domain ESSS PF10183.9 OEU10873.1 - 0.00018 21.7 0.3 0.00034 20.8 0.2 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Astro_capsid_p PF12226.8 OEU10873.1 - 0.31 10.2 9.9 0.35 10.0 9.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 OEU10873.1 - 1.1 7.2 28.1 1.3 7.0 28.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OEU10873.1 - 2.5 6.2 21.3 3 6.0 21.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OEU10873.1 - 4.2 5.6 15.4 5.8 5.1 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3682 PF12446.8 OEU10874.1 - 0.007 16.8 10.3 0.011 16.2 10.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) SURF2 PF05477.11 OEU10874.1 - 0.21 11.2 4.5 0.27 10.9 4.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CsiV PF10972.8 OEU10874.1 - 0.54 9.9 10.4 0.69 9.6 5.0 2.1 1 1 1 2 2 2 0 Peptidoglycan-binding protein, CsiV Presenilin PF01080.17 OEU10874.1 - 5.6 5.6 5.4 6.7 5.4 5.4 1.1 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.6 OEU10875.1 - 0.01 16.2 4.1 0.013 15.9 1.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LPMO_10 PF03067.15 OEU10877.1 - 0.00093 19.9 1.2 0.00093 19.9 1.2 2.6 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-PARP PF00645.18 OEU10878.1 - 2.2e-05 25.3 0.5 9e-05 23.3 0.5 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-BED PF02892.15 OEU10878.1 - 0.0063 16.5 0.1 0.022 14.8 0.1 2.0 1 0 0 1 1 1 1 BED zinc finger EF-hand_7 PF13499.6 OEU10878.1 - 0.046 14.2 0.0 0.67 10.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Steroid_dh PF02544.16 OEU10879.1 - 1e-23 84.0 8.3 1e-23 84.0 8.3 3.6 3 1 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OEU10879.1 - 0.00014 21.5 0.2 0.00034 20.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OEU10879.1 - 0.00053 20.4 0.4 0.0012 19.3 0.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase PBP1_TM PF14812.6 OEU10879.1 - 0.2 12.1 7.4 0.5 10.8 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MAGI_u1 PF16663.5 OEU10879.1 - 0.33 11.1 4.1 0.74 9.9 4.1 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI WD40 PF00400.32 OEU10880.1 - 4.7e-24 84.2 0.2 5.2e-05 23.9 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU10880.1 - 9.7e-13 48.2 0.0 0.0052 17.1 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU10880.1 - 0.0095 15.8 0.1 0.44 10.4 0.0 3.0 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OEU10880.1 - 0.021 13.9 0.0 0.17 10.9 0.0 2.1 1 1 1 2 2 2 0 Coatomer WD associated region DUF4519 PF15012.6 OEU10881.1 - 3.1 8.0 12.7 2.1 8.6 10.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Pro_isomerase PF00160.21 OEU10883.1 - 3.6e-23 82.6 0.0 4.2e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Dynamin_N PF00350.23 OEU10886.1 - 4.6e-15 56.1 1.7 1.2e-13 51.4 0.0 3.9 4 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 OEU10886.1 - 5.2e-06 26.5 0.6 0.00025 21.1 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU10886.1 - 9.4e-06 25.6 0.2 0.00091 19.2 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 OEU10886.1 - 0.013 16.1 0.0 0.013 16.1 0.0 3.9 4 0 0 4 4 4 0 ABC transporter AAA_16 PF13191.6 OEU10886.1 - 0.028 14.8 1.1 0.11 12.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain FlaC_arch PF05377.11 OEU10886.1 - 0.88 10.0 12.5 7.9 7.0 0.1 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) 7tm_3 PF00003.22 OEU10888.1 - 5.9e-26 91.7 22.0 1e-25 90.9 22.0 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Sulfotransfer_2 PF03567.14 OEU10890.1 - 0.1 12.5 0.1 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 Sulfotransferase family 2OG-FeII_Oxy_2 PF13532.6 OEU10891.1 - 2.9e-11 43.9 0.1 2.9e-11 43.9 0.1 4.0 2 2 2 4 4 4 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.17 OEU10891.1 - 3e-09 36.8 0.1 3e-09 36.8 0.1 3.7 2 1 1 3 3 3 1 SAD/SRA domain TFIIA PF03153.13 OEU10891.1 - 0.00032 20.8 21.2 0.00032 20.8 21.2 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 OEU10891.1 - 3.7 6.7 8.0 0.31 10.2 1.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_pol_Rbc25 PF08292.12 OEU10891.1 - 6.8 6.9 7.0 1.7 8.9 2.5 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 MCD PF05292.11 OEU10891.1 - 7.5 6.0 10.3 3.3 7.2 6.3 2.2 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Herpes_teg_N PF04843.12 OEU10893.1 - 0.11 12.1 0.4 0.2 11.3 0.1 1.6 1 1 1 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region Ank_2 PF12796.7 OEU10894.1 - 0.00076 20.0 0.0 0.017 15.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OEU10894.1 - 0.0053 17.1 0.2 0.14 12.7 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 OEU10894.1 - 0.022 15.2 0.2 0.77 10.5 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 OEU10894.1 - 0.027 14.8 0.1 0.26 11.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-RanBP PF00641.18 OEU10895.1 - 0.088 12.2 2.6 0.28 10.5 2.6 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others NCD3G PF07562.14 OEU10895.1 - 0.2 11.7 3.0 0.47 10.5 3.0 1.6 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DAO PF01266.24 OEU10896.1 - 2e-18 67.1 0.0 3.8e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OEU10896.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Macoilin PF09726.9 OEU10896.1 - 9.9 4.6 10.8 1.8 7.0 4.6 2.0 2 0 0 2 2 2 0 Macoilin family EF-hand_6 PF13405.6 OEU10897.1 - 1e-06 28.2 0.4 0.053 13.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OEU10897.1 - 2.8e-06 26.5 0.6 0.034 13.7 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OEU10897.1 - 0.00011 21.6 0.7 0.058 12.9 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU10897.1 - 0.00021 21.7 0.4 0.0051 17.2 0.1 2.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 OEU10897.1 - 0.016 15.5 0.1 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 OEU10897.1 - 0.017 15.0 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 EF hand Mntp PF02659.15 OEU10897.1 - 0.15 11.8 0.2 0.33 10.7 0.2 1.6 1 0 0 1 1 1 0 Putative manganese efflux pump DUF4196 PF13846.6 OEU10899.1 - 0.35 11.1 3.9 0.75 10.0 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) zf-MYND PF01753.18 OEU10900.1 - 3.3e-06 27.1 13.9 1.4e-05 25.1 13.9 2.2 1 1 0 1 1 1 1 MYND finger Trp_repressor PF01371.19 OEU10900.1 - 0.13 12.4 0.0 0.88 9.7 0.0 2.1 2 0 0 2 2 2 0 Trp repressor protein HHH_3 PF12836.7 OEU10901.1 - 3e-14 53.0 0.0 7.9e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 OEU10901.1 - 1.3e-12 48.3 0.6 1.5e-11 44.8 0.0 3.0 2 1 0 2 2 2 1 Tex protein YqgF-like domain Tex_N PF09371.10 OEU10901.1 - 5.1e-09 36.0 0.0 1.6e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_9 PF17674.1 OEU10901.1 - 2.8e-06 28.1 0.0 2.4e-05 25.1 0.0 2.8 1 0 0 1 1 1 1 HHH domain HHH_7 PF14635.6 OEU10901.1 - 5.1e-05 23.6 0.0 0.00017 21.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 OEU10901.1 - 0.0018 18.6 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Sigma54_activ_2 PF14532.6 OEU10901.1 - 0.058 13.5 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain PBP1_TM PF14812.6 OEU10903.1 - 3.3 8.2 19.3 4 7.9 14.0 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7tm_3 PF00003.22 OEU10904.1 - 4.6e-17 62.5 10.3 6.1e-17 62.1 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Mem_trans PF03547.18 OEU10904.1 - 0.012 14.0 3.0 0.017 13.5 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Trimer_CC PF08954.11 OEU10904.1 - 0.11 12.1 0.9 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Trimerisation motif DUF4383 PF14325.6 OEU10904.1 - 0.3 11.4 6.4 0.58 10.4 4.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) Na_Ca_ex PF01699.24 OEU10904.1 - 0.8 9.7 10.1 2.8 7.9 10.1 2.1 1 1 0 1 1 1 0 Sodium/calcium exchanger protein Frag1 PF10277.9 OEU10904.1 - 2.8 7.4 11.5 6.6 6.2 11.5 1.6 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4834 PF16118.5 OEU10904.1 - 7.3 7.6 6.9 1.7 9.7 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SBP_bac_1 PF01547.25 OEU10905.1 - 1.3e-07 31.9 0.1 1.5e-07 31.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 OEU10905.1 - 5.5e-07 29.7 0.0 5.5e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Silic_transp PF03842.13 OEU10907.1 - 2.6e-137 458.2 23.7 2.9e-137 458.1 23.7 1.0 1 0 0 1 1 1 1 Silicon transporter DUF5499 PF17603.2 OEU10908.1 - 0.0021 18.6 3.3 0.38 11.4 0.2 3.2 2 1 0 3 3 3 2 Family of unknown function (DUF5499) Adhesin_P1_N PF18652.1 OEU10908.1 - 0.32 11.0 5.2 2.2 8.4 0.4 3.7 2 1 1 3 3 3 0 Adhesin P1 N-terminal domain 7tm_1 PF00001.21 OEU10910.1 - 0.069 12.5 14.9 0.57 9.4 14.5 2.5 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF202 PF02656.15 OEU10910.1 - 3 8.4 0.0 3 8.4 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) YqaJ PF09588.10 OEU10912.1 - 3.5e-13 49.9 0.1 2.6e-12 47.1 0.1 2.2 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain DUF1828 PF08861.10 OEU10912.1 - 0.3 11.4 1.6 0.65 10.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1828 Cytochrom_B_C PF00032.17 OEU10913.1 - 0.39 11.0 3.9 0.2 12.0 0.7 2.1 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Neur_chan_LBD PF02931.23 OEU10914.1 - 2.3e-20 73.0 0.1 4.4e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OEU10914.1 - 9.3e-05 22.6 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region FxsA PF04186.13 OEU10914.1 - 0.14 12.2 0.4 1.3 9.2 0.0 2.3 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein Branch PF02485.21 OEU10915.1 - 0.00057 19.5 1.8 0.00085 18.9 0.5 1.8 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Aa_trans PF01490.18 OEU10916.1 - 6.7e-37 127.2 18.0 7.4e-35 120.4 18.0 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Chloroa_b-bind PF00504.21 OEU10918.1 - 8.5e-31 107.7 0.1 1.3e-30 107.1 0.1 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein LRS4 PF10422.9 OEU10920.1 - 0.28 10.7 6.6 0.3 10.6 6.6 1.0 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Gly_transf_sug PF04488.15 OEU10921.1 - 2.2e-09 37.8 0.2 6.9e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU10921.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.16 OEU10922.1 - 2.9e-18 65.9 4.3 2.9e-18 65.9 4.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OEU10922.1 - 0.28 9.4 11.9 1.1 7.5 2.9 2.3 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GpcrRhopsn4 PF10192.9 OEU10922.1 - 0.6 9.5 15.5 0.58 9.5 3.3 3.9 4 0 0 4 4 4 0 Rhodopsin-like GPCR transmembrane domain DUF3784 PF12650.7 OEU10922.1 - 7.5 6.8 19.2 3.9 7.7 0.9 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3784) SPX PF03105.19 OEU10923.1 - 3.7e-13 50.2 24.6 5.1e-07 29.9 8.0 4.1 2 1 1 3 3 3 2 SPX domain DUF2722 PF10846.8 OEU10923.1 - 0.017 14.1 13.3 0.17 10.8 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DRY_EERY PF09750.9 OEU10923.1 - 0.37 11.1 3.9 0.93 9.8 3.9 1.7 1 0 0 1 1 1 0 Alternative splicing regulator MAGE_N PF12440.8 OEU10923.1 - 1.3 9.7 11.0 2.4 8.9 2.4 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ank_2 PF12796.7 OEU10925.1 - 0.0052 17.3 0.0 0.041 14.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Presenilin PF01080.17 OEU10927.1 - 3.9 6.1 18.6 8.6 5.0 15.0 2.1 2 0 0 2 2 2 0 Presenilin PRMT5 PF05185.16 OEU10929.1 - 0.042 13.7 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DoxX_2 PF13564.6 OEU10930.1 - 0.0011 19.0 1.7 0.0022 18.1 1.7 1.6 1 1 0 1 1 1 1 DoxX-like family DUF4605 PF15378.6 OEU10930.1 - 0.7 9.8 5.5 1.2 9.1 0.0 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4605) Glyco_transf_17 PF04724.13 OEU10933.1 - 5.2e-05 22.4 0.1 0.00014 21.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 17 Mpv17_PMP22 PF04117.12 OEU10935.1 - 8.8e-16 57.9 1.1 1.6e-15 57.1 1.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sulfotransfer_3 PF13469.6 OEU10936.1 - 0.0083 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Sulfotransferase family AAA_30 PF13604.6 OEU10937.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 OEU10938.1 - 1.3e-15 57.2 0.0 1.5e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU10938.1 - 7.2e-11 42.3 0.0 3.4e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU10938.1 - 3.7e-07 30.6 0.0 4.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU10938.1 - 2.3e-05 24.3 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU10938.1 - 3.3e-05 23.6 0.0 5.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OEU10938.1 - 0.00034 20.7 0.0 0.00044 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 OEU10938.1 - 0.019 14.9 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU10938.1 - 0.02 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Spo7_2_N PF15407.6 OEU10938.1 - 0.045 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 DUF953 PF06110.11 OEU10938.1 - 0.14 11.7 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DnaJ PF00226.31 OEU10939.1 - 1.3e-09 38.0 1.7 8.7e-07 29.0 0.4 2.9 2 0 0 2 2 2 2 DnaJ domain KH_1 PF00013.29 OEU10939.1 - 3.2e-08 33.3 0.1 7.5e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 KH domain RINGv PF12906.7 OEU10939.1 - 5.1e-08 32.9 12.1 5.1e-08 32.9 12.1 2.1 2 0 0 2 2 2 1 RING-variant domain FRG2 PF15315.6 OEU10939.1 - 2.3 8.4 6.3 8 6.6 6.3 1.9 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Vasculin PF15337.6 OEU10940.1 - 0.057 14.3 7.1 0.48 11.3 7.1 1.9 1 1 0 1 1 1 0 Vascular protein family Vasculin-like 1 NosD PF05048.13 OEU10940.1 - 0.9 8.7 15.1 1.3 8.2 15.1 1.3 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) OTU PF02338.19 OEU10941.1 - 1.3e-05 25.7 0.3 0.00058 20.4 0.3 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease SAP PF02037.27 OEU10941.1 - 4.4e-05 23.1 0.1 8.3e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 SAP domain Peptidase_C65 PF10275.9 OEU10941.1 - 0.0025 17.3 1.7 0.019 14.5 1.7 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain MoeA_N PF03453.17 OEU10942.1 - 0.00082 19.2 0.2 1.7 8.4 0.1 2.7 2 1 0 2 2 2 2 MoeA N-terminal region (domain I and II) GP40 PF11025.8 OEU10942.1 - 0.014 15.1 1.7 4.8 6.9 0.1 2.8 2 1 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium DUF3746 PF12562.8 OEU10944.1 - 0.3 11.1 1.6 3.4 7.6 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3746) PhoLip_ATPase_C PF16212.5 OEU10945.1 - 3.1e-36 125.4 13.2 3.1e-36 125.4 13.2 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OEU10945.1 - 7.6e-13 48.0 1.2 3.4e-12 45.9 1.2 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OEU10945.1 - 3.1e-09 37.5 3.0 0.00045 20.6 0.3 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU10945.1 - 0.00032 20.7 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OEU10945.1 - 0.00043 19.9 0.0 0.0049 16.4 0.0 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OEU10945.1 - 0.02 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PsbW PF07123.12 OEU10948.1 - 0.0018 18.3 0.1 0.0022 18.0 0.1 1.1 1 0 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) DUF2742 PF10888.8 OEU10948.1 - 0.029 14.6 0.1 0.033 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) UNC80 PF15778.5 OEU10948.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Cation channel complex component UNC80 Chordopox_G3 PF06129.12 OEU10951.1 - 0.58 10.9 4.1 7.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus G3 protein GMC_oxred_C PF05199.13 OEU10953.1 - 5.7e-05 23.7 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OEU10953.1 - 0.00026 20.2 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GMC_oxred_N PF00732.19 OEU10953.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_9 PF13454.6 OEU10953.1 - 0.085 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pox_TAA1 PF03295.14 OEU10954.1 - 0.0095 15.8 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 1 Poxvirus trans-activator protein A1 C-terminal DUF3872 PF12988.7 OEU10954.1 - 0.054 13.3 0.1 16 5.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3872) CRAL_TRIO PF00650.20 OEU10954.1 - 0.1 12.3 0.0 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 CRAL/TRIO domain Serglycin PF04360.12 OEU10954.1 - 0.28 11.1 8.4 0.13 12.2 0.3 2.3 2 0 0 2 2 2 0 Serglycin AOX PF01786.17 OEU10955.1 - 8e-27 94.2 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase DDE_Tnp_1_7 PF13843.6 OEU10956.1 - 2.1e-15 56.9 0.3 3.3e-15 56.3 0.3 1.2 1 0 0 1 1 1 1 Transposase IS4 Beta_helix_2 PF18835.1 OEU10957.1 - 0.015 15.0 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase Clusterin PF01093.17 OEU10957.1 - 0.034 13.2 0.5 0.047 12.7 0.5 1.2 1 0 0 1 1 1 0 Clusterin CSD PF00313.22 OEU10960.1 - 1.4e-10 40.9 0.1 0.00023 21.0 0.0 2.8 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain KAsynt_C_assoc PF16197.5 OEU10960.1 - 0.038 14.4 1.6 0.8 10.2 0.0 2.9 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension PriA_3primeBD PF17764.1 OEU10960.1 - 9.7 6.2 10.2 17 5.3 0.8 3.6 2 1 1 3 3 3 0 3′ DNA-binding domain (3′BD) Peptidase_S10 PF00450.22 OEU10961.1 - 9.4e-58 196.6 0.0 2.9e-57 194.9 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase SAP PF02037.27 OEU10963.1 - 2.7e-12 46.1 3.2 3.7e-05 23.3 0.1 2.4 2 0 0 2 2 2 2 SAP domain Beta_elim_lyase PF01212.21 OEU10964.1 - 4.2e-18 65.7 0.0 7.2e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Beta-eliminating lyase DUF4116 PF13475.6 OEU10967.1 - 3e-17 62.1 5.6 2.9e-06 26.9 0.1 6.1 8 0 0 8 8 8 4 Domain of unknown function (DUF4116) Nramp PF01566.18 OEU10969.1 - 2.8e-83 279.9 20.2 3.2e-83 279.7 20.2 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein ATP-synt_S1 PF05827.12 OEU10969.1 - 5.2 6.9 6.5 1 9.2 2.6 1.8 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Pox_Ag35 PF03286.14 OEU10970.1 - 0.88 9.3 7.0 0.82 9.4 2.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sulfate_transp PF00916.20 OEU10971.1 - 7.9e-19 67.7 14.8 2.4e-17 62.8 14.8 2.5 1 1 0 1 1 1 1 Sulfate permease family Mito_carr PF00153.27 OEU10972.1 - 9.9e-13 47.8 0.1 1.8e-09 37.4 0.2 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein TIC20 PF16166.5 OEU10973.1 - 1.5e-12 47.6 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like EF-hand_1 PF00036.32 OEU10973.1 - 5.1e-11 41.3 0.1 7.5e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU10973.1 - 3e-09 37.2 0.0 8.3e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU10973.1 - 9.7e-09 34.3 0.3 8.5e-06 25.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU10973.1 - 1.4e-08 34.0 0.1 0.00019 21.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU10973.1 - 0.00011 22.0 0.1 0.00032 20.5 0.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OEU10973.1 - 0.0012 19.1 0.0 0.0038 17.5 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU10973.1 - 0.0031 17.8 0.2 0.0094 16.3 0.1 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Spc42p PF11544.8 OEU10973.1 - 0.014 15.3 0.4 2.6 8.1 0.4 2.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p HD PF01966.22 OEU10975.1 - 6.5e-13 49.0 0.1 2e-12 47.4 0.1 1.9 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 OEU10975.1 - 0.00086 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Sulfatase PF00884.23 OEU10976.1 - 4.7e-41 141.2 0.3 7.4e-41 140.5 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU10976.1 - 1.7e-07 31.2 0.0 0.015 14.9 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OEU10976.1 - 0.0007 19.8 0.3 0.0027 17.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 OEU10976.1 - 0.014 14.0 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 OEU10976.1 - 0.025 14.0 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Metalloenzyme superfamily AAA PF00004.29 OEU10977.1 - 2.4e-05 24.8 0.8 4.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OEU10977.1 - 3.8e-05 23.3 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 OEU10977.1 - 0.00039 20.4 0.2 0.36 10.7 0.1 2.4 2 0 0 2 2 2 2 NTPase AAA_16 PF13191.6 OEU10977.1 - 0.00075 19.9 0.0 0.0035 17.8 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OEU10977.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OEU10977.1 - 0.0018 18.0 0.0 0.0051 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OEU10977.1 - 0.0056 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 OEU10977.1 - 0.0079 15.3 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_2 PF07724.14 OEU10977.1 - 0.03 14.4 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OEU10977.1 - 0.046 13.5 0.1 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OEU10977.1 - 0.055 13.3 0.2 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OEU10977.1 - 0.09 13.0 0.6 1.4 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 OEU10977.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer zf-PARP PF00645.18 OEU10978.1 - 2.2e-07 31.6 0.4 2.2e-07 31.6 0.4 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region XPA_C PF05181.12 OEU10978.1 - 0.0023 17.9 0.1 0.006 16.5 0.0 1.7 2 0 0 2 2 2 1 XPA protein C-terminus TackOD1 PF18551.1 OEU10978.1 - 0.0046 16.6 4.1 0.0046 16.6 4.1 1.7 2 0 0 2 2 2 1 Thaumarchaeal output domain 1 DUF2797 PF10977.8 OEU10978.1 - 0.0078 16.1 2.3 0.016 15.1 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) Amidoligase_2 PF12224.8 OEU10979.1 - 1.3e-19 70.9 9.0 3.4e-19 69.5 0.0 3.6 3 1 1 4 4 4 2 Putative amidoligase enzyme zf-C2H2_jaz PF12171.8 OEU10979.1 - 0.00055 20.2 6.8 0.28 11.5 1.4 3.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OEU10979.1 - 0.01 16.1 0.1 0.01 16.1 0.1 3.9 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OEU10979.1 - 0.074 12.8 19.1 0.026 14.3 3.5 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF4187 PF13821.6 OEU10979.1 - 1.2 9.0 4.4 28 4.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zf-C2H2_4 PF13894.6 OEU10979.1 - 1.8 9.6 20.2 0.63 11.0 1.2 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger UIM PF02809.20 OEU10979.1 - 8.3 6.6 7.5 20 5.4 0.6 3.7 3 1 0 3 3 3 0 Ubiquitin interaction motif LRR_4 PF12799.7 OEU10980.1 - 2.8e-05 24.4 0.5 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU10980.1 - 0.0072 16.1 1.5 0.025 14.3 1.1 2.0 1 1 1 2 2 2 2 Leucine rich repeat His_Phos_1 PF00300.22 OEU10981.1 - 2e-18 66.8 0.4 6.4e-17 61.9 0.4 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FANCF PF11107.8 OEU10982.1 - 0.017 14.3 0.3 0.023 13.9 0.3 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Ctf8 PF09696.10 OEU10983.1 - 1.7e-10 41.4 0.1 3.2e-10 40.5 0.1 1.4 1 1 0 1 1 1 1 Ctf8 Pkinase PF00069.25 OEU10984.1 - 8.1e-64 215.5 0.0 1.3e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU10984.1 - 1.2e-31 110.0 0.3 3.6e-31 108.4 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU10984.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU10984.1 - 0.011 15.0 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OEU10984.1 - 0.018 14.6 0.1 0.037 13.6 0.1 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OEU10984.1 - 0.026 13.5 0.1 0.045 12.7 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OEU10984.1 - 0.11 12.4 0.1 0.47 10.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 OEU10985.1 - 8.5e-09 35.7 0.0 1.2e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU10985.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU10985.1 - 3.9e-05 23.6 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU10985.1 - 0.0081 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF1230 PF06799.11 OEU10986.1 - 3.9e-41 140.5 0.0 4.3e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 ParA PF10609.9 OEU10987.1 - 2.2e-75 253.3 0.0 1.2e-67 227.9 0.1 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OEU10987.1 - 2.2e-10 40.7 0.0 1.1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OEU10987.1 - 1.7e-07 31.4 0.1 9.2e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OEU10987.1 - 5.7e-07 29.0 5.1 1.3e-06 27.8 0.9 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 OEU10987.1 - 5.5e-06 25.8 0.1 3.7e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ MeaB PF03308.16 OEU10987.1 - 0.00061 18.9 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 OEU10987.1 - 0.00088 18.8 0.1 0.0027 17.2 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 OEU10987.1 - 0.0028 17.5 0.2 0.0055 16.6 0.2 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 OEU10987.1 - 0.0046 16.2 0.1 0.0098 15.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 OEU10987.1 - 0.012 15.2 0.2 0.031 13.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OEU10987.1 - 0.021 14.8 0.9 0.039 13.9 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_26 PF13500.6 OEU10987.1 - 0.03 14.2 1.9 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 OEU10987.1 - 0.033 13.7 1.3 0.71 9.3 0.5 2.9 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Rad17 PF03215.15 OEU10987.1 - 0.039 13.9 0.2 0.089 12.7 0.2 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 OEU10987.1 - 0.059 13.0 0.1 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DAP3 PF10236.9 OEU10987.1 - 0.083 12.0 0.5 0.19 10.9 0.5 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 End_beta_barrel PF12195.8 OEU10987.1 - 0.084 12.8 3.1 0.2 11.7 3.1 1.6 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase IstB_IS21 PF01695.17 OEU10987.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OEU10987.1 - 0.11 12.4 0.9 0.18 11.7 0.2 1.7 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 OEU10987.1 - 0.13 12.1 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 OEU10987.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OEU10987.1 - 0.16 11.8 0.2 0.38 10.7 0.2 1.6 1 0 0 1 1 1 0 NACHT domain DUF3439 PF11921.8 OEU10987.1 - 0.8 9.7 4.9 2.1 8.3 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HA PF03457.14 OEU10988.1 - 1.6e-34 118.0 0.3 4.4e-20 71.8 0.0 2.5 2 0 0 2 2 2 2 Helicase associated domain Glypican PF01153.19 OEU10988.1 - 0.0049 15.8 2.3 0.0064 15.4 2.3 1.2 1 0 0 1 1 1 1 Glypican Na_trans_assoc PF06512.13 OEU10988.1 - 0.013 15.8 3.8 0.015 15.5 3.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DivIC PF04977.15 OEU10988.1 - 0.18 11.6 9.5 12 5.7 7.9 3.6 3 1 0 3 3 3 0 Septum formation initiator zf-CpG_bind_C PF12269.8 OEU10988.1 - 0.56 9.9 4.7 1.1 9.0 4.7 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain ZapB PF06005.12 OEU10988.1 - 0.87 10.1 13.3 0.96 9.9 8.8 3.1 2 2 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 OEU10988.1 - 1.3 9.5 11.5 2.1 8.8 7.0 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) RNA_pol_3_Rpc31 PF11705.8 OEU10988.1 - 2 8.6 10.6 4.1 7.6 10.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SLX9 PF15341.6 OEU10988.1 - 5.2 7.5 8.0 8.8 6.7 0.9 2.4 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Lactamase_B_2 PF12706.7 OEU10989.1 - 6.2e-18 65.0 0.2 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU10989.1 - 9.8e-10 38.8 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OEU10989.1 - 6.1e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease WW PF00397.26 OEU10990.1 - 9.2e-12 44.8 4.1 1.9e-11 43.8 4.1 1.6 1 0 0 1 1 1 1 WW domain CD225 PF04505.12 OEU10990.1 - 8.5e-11 41.8 0.9 1.4e-10 41.1 0.9 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Glyco_hyd_101C PF17451.2 OEU10990.1 - 0.027 14.8 0.1 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain FKBP_C PF00254.28 OEU10991.1 - 7.4e-24 83.9 0.0 1.1e-23 83.4 0.0 1.3 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MMR_HSR1 PF01926.23 OEU10993.1 - 4.3e-17 62.2 0.1 6.6e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU10993.1 - 7.1e-08 32.1 0.2 6.5e-07 29.0 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OEU10993.1 - 7.4e-07 29.2 0.1 0.00022 21.2 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OEU10993.1 - 8.4e-06 25.9 0.6 0.011 15.8 0.3 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 OEU10993.1 - 0.00026 20.6 0.0 0.069 12.7 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 OEU10993.1 - 0.00029 21.0 0.0 0.0086 16.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 OEU10993.1 - 0.032 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Septin Ras PF00071.22 OEU10993.1 - 0.13 11.8 0.1 0.75 9.4 0.0 2.1 2 0 0 2 2 2 0 Ras family IBR PF01485.21 OEU10994.1 - 6.9e-08 32.6 26.1 4.2e-06 26.9 13.1 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain PPR_2 PF13041.6 OEU10996.1 - 1.6e-31 108.2 0.7 3.6e-13 49.5 0.0 3.0 1 1 2 3 3 3 3 PPR repeat family PPR PF01535.20 OEU10996.1 - 3.4e-26 89.6 1.9 2.6e-09 36.7 0.1 4.0 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 OEU10996.1 - 1.7e-23 82.5 0.0 2e-13 50.2 0.0 3.0 1 1 2 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU10996.1 - 1.8e-18 66.0 0.2 0.00012 21.7 0.0 4.1 4 0 0 4 4 4 4 PPR repeat PPR_long PF17177.4 OEU10996.1 - 9.3e-09 35.0 0.0 4.8e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 OEU10996.1 - 0.003 16.5 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 ANAPC3 PF12895.7 OEU10996.1 - 0.0045 17.2 0.1 0.091 13.0 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OEU10996.1 - 0.011 15.7 0.1 39 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU10996.1 - 0.062 13.8 0.1 1.6 9.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OEU10996.1 - 0.072 13.1 0.0 0.44 10.6 0.0 2.0 1 1 0 1 1 1 0 Putative TPR-like repeat Clathrin PF00637.20 OEU10996.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Region in Clathrin and VPS FtsK_gamma PF09397.10 OEU10996.1 - 0.087 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Ftsk gamma domain TPR_6 PF13174.6 OEU10996.1 - 0.18 12.5 0.1 1.2e+02 3.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mut7-C PF01927.16 OEU10997.1 - 2.2e-18 66.7 0.2 4.4e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Mut7-C RNAse domain Exo_endo_phos PF03372.23 OEU10997.1 - 2.2e-09 37.2 0.7 6.6e-06 25.8 0.2 3.1 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 OEU10998.1 - 1.9e-37 126.9 0.0 1.4e-16 60.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OEU10998.1 - 6.8e-05 22.8 0.0 0.3 11.1 0.0 3.2 3 0 0 3 3 3 1 DbpA RNA binding domain RRM_occluded PF16842.5 OEU10998.1 - 0.00014 21.6 0.0 0.03 14.2 0.0 3.3 3 2 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OEU10998.1 - 0.00018 21.5 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 OEU10998.1 - 0.042 13.5 0.2 14 5.5 0.0 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain BRCT PF00533.26 OEU10999.1 - 4.9e-06 26.8 0.0 3.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Wbp11 PF09429.10 OEU10999.1 - 0.94 9.9 8.7 1.5 9.3 7.1 2.1 2 0 0 2 2 2 0 WW domain binding protein 11 Imm5 PF14423.6 OEU10999.1 - 1.1 9.4 3.7 0.66 10.2 0.9 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 DoxX_2 PF13564.6 OEU10999.1 - 5.1 7.3 8.4 0.69 10.0 0.6 2.4 2 0 0 2 2 2 0 DoxX-like family Cupin_8 PF13621.6 OEU11001.1 - 1.4e-40 139.6 7.3 4.2e-21 75.8 2.3 2.4 1 1 1 2 2 2 2 Cupin-like domain Lipase_GDSL PF00657.22 OEU11002.1 - 0.00037 20.5 0.0 0.34 10.9 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OEU11002.1 - 0.00048 20.6 0.2 0.52 10.7 0.1 2.2 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family FA_desaturase PF00487.24 OEU11003.1 - 9.3e-08 32.2 15.6 7.7e-07 29.2 15.1 2.1 1 1 0 1 1 1 1 Fatty acid desaturase Band_7 PF01145.25 OEU11005.1 - 5e-26 91.8 0.5 6.6e-26 91.4 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OEU11005.1 - 0.00034 20.4 0.2 0.00058 19.6 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family HSP20 PF00011.21 OEU11006.1 - 3e-06 27.3 0.0 0.0015 18.7 0.0 2.3 1 1 1 2 2 2 2 Hsp20/alpha crystallin family SR-25 PF10500.9 OEU11006.1 - 0.0021 17.7 1.8 0.0024 17.5 1.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ArsA_HSP20 PF17886.1 OEU11006.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA DUF3537 PF12056.8 OEU11006.1 - 0.2 10.5 2.2 0.25 10.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Glyoxalase_3 PF13468.6 OEU11008.1 - 8.1e-15 55.4 0.0 9.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OEU11008.1 - 0.00054 20.2 0.0 0.0017 18.6 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 OEU11008.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gag_pre-integrs PF13976.6 OEU11009.1 - 1.9e-07 30.8 1.1 9.5e-07 28.6 1.1 2.2 1 1 0 1 1 1 1 GAG-pre-integrase domain BTB PF00651.31 OEU11011.1 - 6.7e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MtrB PF05440.12 OEU11013.1 - 0.1 13.0 0.1 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B PMSI1 PF15322.6 OEU11013.1 - 3.4 7.0 9.9 3.8 6.9 0.1 2.6 3 0 0 3 3 3 0 Protein missing in infertile sperm 1, putative LRR_4 PF12799.7 OEU11014.1 - 1.3 9.6 22.5 1.9 9.0 0.2 4.9 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 OEU11015.1 - 4.5e-43 144.4 32.8 6.9e-07 29.9 0.3 10.9 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp13 PF08625.11 OEU11015.1 - 3.5e-34 117.7 2.6 6.7e-34 116.8 2.6 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OEU11015.1 - 9.4e-10 38.7 3.0 0.22 11.8 0.0 6.4 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.10 OEU11015.1 - 0.057 13.1 1.3 0.14 11.8 1.3 1.6 1 1 0 1 1 1 0 UTP15 C terminal SET PF00856.28 OEU11016.1 - 1.8e-05 25.2 0.0 3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 SET domain F-box-like PF12937.7 OEU11017.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like PL48 PF15903.5 OEU11018.1 - 0.004 16.2 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 Ku_PK_bind PF08785.11 OEU11018.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Aa_trans PF01490.18 OEU11019.1 - 9.6e-24 83.8 14.3 2.6e-14 52.7 8.9 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU11019.1 - 0.00024 20.2 8.6 0.0041 16.2 9.5 2.2 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family 7tm_1 PF00001.21 OEU11019.1 - 0.0019 17.6 1.7 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF2214 PF09980.9 OEU11019.1 - 0.013 15.3 0.2 0.013 15.3 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2214) Bap31 PF05529.12 OEU11019.1 - 0.016 15.0 1.9 1.9 8.3 0.6 2.8 2 1 0 2 2 2 0 Bap31/Bap29 transmembrane region Tetraspanin PF00335.20 OEU11019.1 - 0.017 14.8 0.7 0.31 10.7 0.6 2.5 1 1 0 1 1 1 0 Tetraspanin family DUF2427 PF10348.9 OEU11019.1 - 0.025 14.3 2.9 0.032 14.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) EphA2_TM PF14575.6 OEU11019.1 - 0.056 14.3 0.1 0.056 14.3 0.1 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain GNAT_acetyltr_2 PF13718.6 OEU11019.1 - 0.061 12.7 0.0 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Pro_isomerase PF00160.21 OEU11020.1 - 2.8e-08 34.2 0.2 7.5e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LAP1C PF05609.12 OEU11020.1 - 0.066 12.3 4.7 0.096 11.8 4.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hydin_ADK PF17213.3 OEU11020.1 - 0.072 13.4 1.7 0.12 12.6 1.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CPSF100_C PF13299.6 OEU11020.1 - 0.78 9.9 5.5 1.2 9.3 5.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 OEU11020.1 - 3.2 6.2 7.5 0.095 11.2 1.5 1.4 2 0 0 2 2 2 0 Macoilin family Myc_N PF01056.18 OEU11020.1 - 5.3 6.8 11.2 0.27 11.1 5.4 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Silic_transp PF03842.13 OEU11021.1 - 4.7e-61 206.7 0.1 5.6e-61 206.4 0.1 1.0 1 0 0 1 1 1 1 Silicon transporter DUF202 PF02656.15 OEU11021.1 - 1 9.9 4.0 2 8.9 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TauD PF02668.16 OEU11022.1 - 3e-20 73.1 0.0 4e-19 69.4 0.0 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Inp1 PF12634.7 OEU11022.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 HPP PF04982.13 OEU11023.1 - 5.4e-21 75.0 7.3 6.1e-21 74.8 7.3 1.0 1 0 0 1 1 1 1 HPP family DUF1700 PF08006.11 OEU11023.1 - 0.64 9.5 5.2 0.46 10.0 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) FUSC_2 PF13515.6 OEU11023.1 - 0.65 10.1 9.0 9 6.4 10.0 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein-like VirE3 PF06661.11 OEU11024.1 - 0.0039 16.5 0.9 0.005 16.2 0.9 1.1 1 0 0 1 1 1 1 VirE3 potato_inhibit PF00280.18 OEU11026.1 - 0.02 15.6 0.0 0.084 13.6 0.0 2.0 1 1 0 1 1 1 0 Potato inhibitor I family BBE PF08031.12 OEU11027.1 - 8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FXR_C3 PF16097.5 OEU11027.1 - 0.46 11.2 2.5 0.68 10.7 0.8 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 GyrI-like PF06445.15 OEU11028.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 GyrI-like small molecule binding domain LRR_8 PF13855.6 OEU11029.1 - 8.2e-15 54.3 12.8 1.5e-09 37.4 3.9 3.4 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU11029.1 - 2e-12 47.1 20.5 2.8e-05 24.4 0.9 4.9 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11029.1 - 0.00012 22.1 12.5 0.39 11.4 0.3 6.4 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 OEU11029.1 - 0.0077 16.2 15.2 0.28 11.3 0.2 6.4 7 0 0 7 7 7 1 Leucine Rich repeat BetR PF08667.10 OEU11029.1 - 0.0095 16.0 0.0 3.1 7.8 0.0 3.2 1 1 0 1 1 1 1 BetR domain LRR_8 PF13855.6 OEU11032.1 - 9.6e-09 34.9 8.0 4e-05 23.3 0.6 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU11032.1 - 1.6e-06 28.3 14.7 0.00041 20.7 2.9 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11032.1 - 3.4e-06 26.8 6.5 1.7 9.5 0.1 4.9 4 1 0 4 4 4 3 Leucine Rich Repeat FH2 PF02181.23 OEU11034.1 - 5.8e-73 246.2 11.4 8.1e-73 245.7 11.4 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain GatB_Yqey PF02637.18 OEU11034.1 - 0.0085 16.0 0.1 0.025 14.4 0.1 1.8 1 0 0 1 1 1 1 GatB domain Cor1 PF04803.12 OEU11034.1 - 0.28 11.4 0.0 0.28 11.4 0.0 3.5 4 0 0 4 4 4 0 Cor1/Xlr/Xmr conserved region L31 PF09784.9 OEU11034.1 - 1.6 9.2 4.5 38 4.8 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 TauE PF01925.19 OEU11036.1 - 1e-15 58.0 31.0 1.4e-11 44.5 18.3 3.0 2 2 0 2 2 2 2 Sulfite exporter TauE/SafE TssN PF17555.2 OEU11036.1 - 9.1 5.6 9.8 0.21 10.9 2.2 2.0 2 1 0 2 2 2 0 Type VI secretion system, TssN LRR_8 PF13855.6 OEU11037.1 - 9.1e-19 67.0 37.3 1.3e-05 24.8 1.2 6.8 5 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OEU11037.1 - 6.2e-13 48.7 42.5 0.00069 20.0 0.2 8.0 7 1 0 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11037.1 - 1.6e-07 30.9 32.1 6.3 7.8 0.0 12.6 13 0 0 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU11037.1 - 1.2 9.3 20.9 17 5.7 0.1 7.7 9 0 0 9 9 9 0 Leucine Rich repeat Ribosomal_S5 PF00333.20 OEU11039.1 - 4.3e-26 90.7 0.2 4.3e-26 90.7 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OEU11039.1 - 4.4e-24 83.7 0.0 9.3e-24 82.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OEU11039.1 - 3.2 8.3 19.7 7.3 7.2 19.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 LRR_8 PF13855.6 OEU11040.1 - 4.7e-07 29.5 12.1 0.00026 20.7 0.6 4.4 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 OEU11040.1 - 7.4 7.5 0.0 7.4 7.5 0.0 6.8 9 1 0 9 9 9 0 Leucine Rich Repeat PPP4R2 PF09184.11 OEU11041.1 - 0.2 11.2 9.2 0.26 10.8 9.2 1.1 1 0 0 1 1 1 0 PPP4R2 DUF3446 PF11928.8 OEU11041.1 - 1.8 8.9 23.6 4.5 7.6 5.7 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain CCDC24 PF15669.5 OEU11041.1 - 4 7.3 12.3 1.6 8.5 3.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Chorion_2 PF03964.15 OEU11041.1 - 7 7.5 9.5 3.9 8.4 2.2 2.2 2 0 0 2 2 2 0 Chorion family 2 ATP11 PF06644.11 OEU11041.1 - 9 6.0 8.5 2.5 7.8 4.0 1.9 2 0 0 2 2 2 0 ATP11 protein Sulfatase PF00884.23 OEU11042.1 - 1.2e-40 139.9 1.3 2.8e-40 138.6 1.3 1.6 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU11042.1 - 0.0017 18.0 7.2 0.07 12.7 0.0 3.0 3 1 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase NPR3 PF03666.13 OEU11042.1 - 1.3 7.7 12.4 1.9 7.2 12.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PBP_sp32 PF07222.12 OEU11042.1 - 9.2 5.6 9.9 18 4.6 9.9 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Lactamase_B_2 PF12706.7 OEU11043.1 - 1.3e-30 106.5 0.0 1.9e-30 105.9 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OEU11043.1 - 2.9e-11 43.5 0.0 3.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rhomboid PF01694.22 OEU11044.1 - 1.1e-13 51.5 3.8 1.1e-13 51.5 3.8 2.7 3 0 0 3 3 3 1 Rhomboid family His_Phos_1 PF00300.22 OEU11045.1 - 1.4e-22 80.4 3.9 2e-21 76.6 3.9 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OEU11045.1 - 0.0015 18.0 0.8 0.0022 17.4 0.5 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ofd1_CTDD PF10637.9 OEU11046.1 - 2.9e-61 207.1 2.8 9.4e-58 195.6 1.3 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OEU11046.1 - 2.1e-20 73.2 0.0 4.9e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OEU11046.1 - 2.3e-14 54.0 0.0 4.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Alpha_adaptinC2 PF02883.20 OEU11046.1 - 0.00034 20.9 4.1 0.0078 16.5 0.1 3.1 3 0 0 3 3 3 1 Adaptin C-terminal domain DUF588 PF04535.12 OEU11047.1 - 0.14 12.0 0.2 0.14 12.0 0.2 3.2 5 0 0 5 5 5 0 Domain of unknown function (DUF588) DUF2116 PF09889.9 OEU11047.1 - 0.21 11.6 3.2 0.23 11.4 0.6 2.3 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Herpes_US9 PF06072.11 OEU11047.1 - 0.26 11.2 1.1 0.59 10.1 1.1 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF1676 PF07898.13 OEU11047.1 - 1.8 8.6 10.2 0.11 12.6 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) FA_desaturase PF00487.24 OEU11049.1 - 2.1e-17 63.8 14.3 3.3e-17 63.2 14.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cupin_8 PF13621.6 OEU11050.1 - 4.9e-18 65.8 0.1 4.9e-18 65.8 0.1 1.6 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 OEU11050.1 - 0.00046 19.8 0.1 0.00088 18.8 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 OEU11050.1 - 0.001 18.8 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 OEU11050.1 - 0.0061 17.0 0.0 0.0061 17.0 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase SUIM_assoc PF16619.5 OEU11050.1 - 1.5 8.9 19.1 0.92 9.6 4.4 3.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LCE PF14672.6 OEU11051.1 - 2.9 8.5 8.0 3 8.5 5.2 2.6 2 1 0 2 2 2 0 Late cornified envelope p450 PF00067.22 OEU11052.1 - 7e-22 77.8 14.1 1.7e-17 63.3 0.0 4.1 2 1 2 4 4 4 4 Cytochrome P450 DUF2052 PF09747.9 OEU11052.1 - 1.2 9.2 18.6 3.9 7.6 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF572 PF04502.13 OEU11052.1 - 2.4 7.7 20.5 0.24 11.0 8.5 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF572) DUF3494 PF11999.8 OEU11053.1 - 1.5e-49 168.5 17.5 1.7e-49 168.3 17.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Lipase_GDSL_2 PF13472.6 OEU11054.1 - 5.5e-12 46.4 0.0 1e-11 45.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 OEU11054.1 - 0.012 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 OSK domain VRP3 PF03536.15 OEU11054.1 - 0.12 11.9 0.1 2.4 7.6 0.1 2.1 1 1 0 1 1 1 0 Salmonella virulence-associated 28kDa protein CRAL_TRIO PF00650.20 OEU11055.1 - 0.063 13.0 1.1 0.39 10.4 0.2 2.3 2 0 0 2 2 2 0 CRAL/TRIO domain DUF1772 PF08592.11 OEU11056.1 - 0.011 16.1 0.2 0.019 15.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 OEU11057.1 - 5.2e-21 75.0 43.7 1.3e-17 63.7 26.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 OEU11060.1 - 4.9e-41 140.9 0.0 5.3e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3671 PF12420.8 OEU11061.1 - 0.21 11.7 7.3 1.6 8.8 2.9 3.2 2 1 1 3 3 3 0 Protein of unknown function Mucin PF01456.17 OEU11061.1 - 0.56 10.2 7.0 0.86 9.6 0.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Orai-1 PF07856.12 OEU11061.1 - 7.3 6.2 8.6 27 4.4 8.6 1.9 1 1 0 1 1 1 0 Mediator of CRAC channel activity DUF551 PF04448.12 OEU11062.1 - 1.8 9.6 3.8 1.7 9.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF551) Podoplanin PF05808.11 OEU11062.1 - 5.2 7.1 8.3 10 6.2 2.7 3.1 2 1 0 2 2 2 0 Podoplanin FAM176 PF14851.6 OEU11062.1 - 5.3 6.7 10.2 2.5 7.7 1.6 3.8 4 0 0 4 4 4 0 FAM176 family DUF2167 PF09935.9 OEU11063.1 - 0.01 15.0 0.2 0.016 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) DUF3533 PF12051.8 OEU11063.1 - 0.48 9.3 1.9 0.69 8.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFIIA PF03153.13 OEU11064.1 - 0.00023 21.3 27.0 0.00027 21.1 27.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 OEU11064.1 - 0.017 14.0 18.5 0.021 13.7 18.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.9 OEU11064.1 - 0.2 9.9 22.9 0.23 9.7 22.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_U4 PF03419.13 OEU11064.1 - 0.31 10.3 2.6 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Macoilin PF09726.9 OEU11064.1 - 0.56 8.7 21.4 0.64 8.5 21.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF4484 PF14831.6 OEU11064.1 - 0.83 9.6 16.1 1.1 9.2 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) TMEM51 PF15345.6 OEU11064.1 - 1.1 9.0 19.4 1.8 8.4 19.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 PNISR PF15996.5 OEU11064.1 - 1.3 9.3 23.9 1.9 8.7 23.9 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF4407 PF14362.6 OEU11064.1 - 1.3 8.3 16.4 1.6 8.0 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4638 PF15472.6 OEU11064.1 - 1.4 8.6 17.4 2.1 8.0 17.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SMYLE_N PF18615.1 OEU11064.1 - 1.6 8.2 16.8 2.4 7.6 16.8 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pneumo_att_G PF05539.11 OEU11064.1 - 2.1 7.9 25.1 2.6 7.6 25.1 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GREB1 PF15782.5 OEU11064.1 - 2.3 5.2 19.2 2.6 5.1 19.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 OEU11064.1 - 2.4 7.1 23.7 3.7 6.5 23.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 OEU11064.1 - 5.7 5.9 24.5 7.5 5.5 24.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ndc1_Nup PF09531.10 OEU11064.1 - 8.9 4.9 15.7 11 4.5 15.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TSR PF18487.1 OEU11065.1 - 0.25 11.6 18.1 1.2 9.4 0.3 5.2 4 1 1 5 5 5 0 Thrombospondin type 1 repeat TPR_12 PF13424.6 OEU11066.1 - 3.1e-08 33.8 0.4 0.31 11.4 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU11066.1 - 0.0057 16.7 4.4 4 7.8 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11066.1 - 0.0064 16.3 1.7 5.3 7.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU11066.1 - 0.014 15.3 6.7 3.3 7.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 OEU11066.1 - 3.8 6.1 11.8 8.7 4.9 11.8 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAC1F_C PF16885.5 OEU11066.1 - 4.1 7.0 21.8 0.23 11.1 14.5 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term DUF285 PF03382.14 OEU11067.1 - 4.9e-88 291.0 49.8 2.4e-33 114.4 12.4 2.8 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 DUF4973 PF16343.5 OEU11067.1 - 0.018 15.1 0.7 11 6.0 0.0 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF4973) MAGE PF01454.19 OEU11068.1 - 0.43 10.2 6.5 3.9 7.1 0.0 2.5 2 1 0 2 2 2 0 MAGE family EF-hand_1 PF00036.32 OEU11069.1 - 1.2e-07 30.7 1.0 0.0038 16.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OEU11069.1 - 7.8e-07 29.5 1.0 1.9e-06 28.2 1.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU11069.1 - 1.5e-05 24.6 0.9 0.049 13.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU11069.1 - 0.0094 16.3 0.3 0.023 15.0 0.3 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EMP24_GP25L PF01105.24 OEU11069.1 - 0.025 14.5 1.4 0.037 14.0 1.4 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD F_actin_cap_B PF01115.17 OEU11071.1 - 6.5e-10 39.0 2.2 6.5e-10 39.0 2.2 2.7 2 1 0 2 2 2 1 F-actin capping protein, beta subunit LPMO_10 PF03067.15 OEU11072.1 - 4.1e-05 24.3 0.0 0.00016 22.4 0.0 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Toxin_9 PF02819.15 OEU11072.1 - 7.5 6.9 7.6 0.73 10.2 2.9 1.8 2 0 0 2 2 2 0 Spider toxin DUF3523 PF12037.8 OEU11073.1 - 0.037 13.4 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CDC45 PF02724.14 OEU11074.1 - 0.19 10.0 11.9 0.18 10.0 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PRKCSH-like PF12999.7 OEU11075.1 - 2.3e-10 40.6 8.7 2.3e-10 40.6 8.7 2.6 2 1 0 2 2 2 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 OEU11075.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.4 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Fib_alpha PF08702.10 OEU11075.1 - 0.31 11.2 4.3 0.14 12.4 0.7 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF285 PF03382.14 OEU11076.1 - 1.4e-24 86.2 2.0 2.2e-24 85.5 2.0 1.3 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 PT PF04886.12 OEU11076.1 - 0.0005 19.6 12.4 0.0012 18.4 12.4 1.6 1 0 0 1 1 1 1 PT repeat Herpes_DNAp_acc PF04929.12 OEU11076.1 - 0.25 10.3 7.8 0.35 9.8 7.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor NOT2_3_5 PF04153.18 OEU11077.1 - 7.8e-27 93.9 9.2 8.6e-27 93.8 9.2 1.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OEU11077.1 - 0.039 13.8 2.9 0.046 13.6 2.9 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Not3 PF04065.15 OEU11078.1 - 6.8e-77 258.0 22.0 6.8e-77 258.0 22.0 3.2 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component PAT1 PF09770.9 OEU11078.1 - 0.058 11.7 59.5 0.13 10.5 59.5 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltrn_RNA_4 PF09936.9 OEU11078.1 - 6.7 6.5 21.9 0.079 12.8 12.4 2.4 1 1 1 2 2 2 0 SAM-dependent RNA methyltransferase K1377 PF15352.6 OEU11079.1 - 0.015 13.6 2.9 0.025 12.9 2.9 1.3 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy KptA_kDCL PF18176.1 OEU11079.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain DUF4834 PF16118.5 OEU11079.1 - 3.9 8.5 4.9 0.67 11.0 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) cobW PF02492.19 OEU11080.1 - 1.7e-38 132.0 0.0 3.7e-38 130.9 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU11080.1 - 5.1e-16 58.4 0.0 4.5e-15 55.4 0.0 2.4 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 OEU11080.1 - 0.016 15.8 0.4 0.087 13.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU11080.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ThiI PF02568.14 OEU11084.1 - 0.0022 17.6 9.0 0.19 11.3 0.6 2.2 1 1 1 2 2 2 2 Thiamine biosynthesis protein (ThiI) Malate_synthase PF01274.22 OEU11084.1 - 0.16 10.2 0.4 9.6 4.3 0.0 2.2 2 0 0 2 2 2 0 Malate synthase DUF3579 PF12112.8 OEU11084.1 - 0.2 12.2 1.5 26 5.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) Pox_A9 PF04835.12 OEU11084.1 - 0.2 11.8 9.5 1 9.6 0.0 5.0 3 1 0 3 3 3 0 A9 protein conserved region Croc_4 PF17691.1 OEU11084.1 - 5.5 7.0 9.0 12 6.0 1.5 2.2 2 0 0 2 2 2 0 Contingent replication of cDNA 4 Pyr_redox_2 PF07992.14 OEU11085.1 - 3.2e-05 23.3 0.0 0.00095 18.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU11085.1 - 0.014 15.9 0.0 2.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1840 PF08895.11 OEU11085.1 - 0.026 14.8 0.5 0.026 14.8 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Thi4 PF01946.17 OEU11085.1 - 0.029 13.6 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 OEU11085.1 - 0.035 14.1 0.0 0.43 10.5 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OEU11085.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pox_F16 PF04708.12 OEU11086.1 - 0.084 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein DUF3304 PF11745.8 OEU11086.1 - 0.089 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) Lactamase_B_2 PF12706.7 OEU11088.1 - 1.2e-15 57.5 0.0 4.8e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU11088.1 - 1.5e-10 41.4 0.2 3.5e-08 33.7 0.0 2.3 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OEU11088.1 - 0.0031 17.1 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease 3Beta_HSD PF01073.19 OEU11088.1 - 0.14 11.2 0.2 0.21 10.6 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OEU11088.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DUF3494 PF11999.8 OEU11089.1 - 3.1e-56 190.3 14.4 3.6e-56 190.1 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF2572 PF10833.8 OEU11089.1 - 0.2 11.4 0.2 0.67 9.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) Pox_TAA1 PF03295.14 OEU11090.1 - 0.12 12.3 0.2 3.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal ADH_zinc_N PF00107.26 OEU11091.1 - 6.1e-16 58.6 0.0 8.3e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU11091.1 - 4.6e-06 27.7 0.0 1.7e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OEU11091.1 - 0.0049 16.4 0.2 0.007 15.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 OEU11091.1 - 0.0082 15.9 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 OEU11091.1 - 0.11 11.9 0.6 0.19 11.1 0.6 1.4 1 1 0 1 1 1 0 short chain dehydrogenase DHC_N1 PF08385.12 OEU11093.1 - 8.8e-75 252.4 0.0 2.6e-74 250.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OEU11093.1 - 1.5e-20 73.7 0.3 1.5e-20 73.7 0.3 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DUF4618 PF15397.6 OEU11093.1 - 1.5 8.2 7.0 3.8 6.9 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) AAA_6 PF12774.7 OEU11094.1 - 7.7e-131 435.9 0.7 2.3e-129 431.1 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 OEU11094.1 - 7.6e-67 224.6 0.1 7.6e-67 224.6 0.1 3.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 OEU11094.1 - 5e-60 203.0 0.1 1.8e-59 201.2 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 MT PF12777.7 OEU11094.1 - 1e-39 136.5 7.0 1.8e-39 135.7 7.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DHC_N2 PF08393.13 OEU11094.1 - 2.3e-37 129.1 0.0 2.3e-37 129.1 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 OEU11094.1 - 4.7e-36 124.0 0.4 1.6e-28 99.5 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 OEU11094.1 - 5.5e-26 91.0 0.0 4.4e-25 88.1 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OEU11094.1 - 2.4e-23 82.7 0.0 1.5e-07 31.5 0.0 6.6 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 OEU11094.1 - 1e-17 64.8 0.0 0.00026 21.4 0.0 5.5 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 OEU11094.1 - 1e-14 54.7 2.8 4.1e-14 52.8 0.1 3.3 4 0 0 4 4 2 1 Dynein heavy chain AAA lid domain AAA_18 PF13238.6 OEU11094.1 - 4.7e-12 46.6 0.2 0.18 12.3 0.0 5.4 5 0 0 5 5 4 3 AAA domain AAA_lid_11 PF18198.1 OEU11094.1 - 8.7e-12 45.2 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 OEU11094.1 - 1.3e-10 42.0 6.4 0.065 13.6 0.0 6.3 7 0 0 7 7 4 2 AAA ATPase domain T2SSE PF00437.20 OEU11094.1 - 3.5e-10 39.4 3.9 0.0012 18.0 0.0 4.7 5 0 0 5 5 4 2 Type II/IV secretion system protein AAA_22 PF13401.6 OEU11094.1 - 5.3e-10 39.7 11.7 0.011 15.9 0.0 6.7 8 0 0 8 8 4 3 AAA domain AAA_33 PF13671.6 OEU11094.1 - 1.6e-07 31.5 0.9 0.11 12.7 0.0 5.0 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 OEU11094.1 - 1.2e-05 25.3 4.5 0.13 12.2 0.2 4.5 4 0 0 4 4 4 1 RsgA GTPase AAA_30 PF13604.6 OEU11094.1 - 2.3e-05 24.2 1.2 6.3 6.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_lid_1 PF17857.1 OEU11094.1 - 3.5e-05 23.9 0.0 0.00016 21.8 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 OEU11094.1 - 5.5e-05 22.6 0.2 2.4 7.4 0.1 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family PI3K_P85_iSH2 PF16454.5 OEU11094.1 - 0.0001 22.0 0.4 0.0001 22.0 0.4 3.1 3 0 0 3 3 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RNA_helicase PF00910.22 OEU11094.1 - 0.00018 21.9 0.1 16 5.9 0.0 4.7 4 0 0 4 4 4 0 RNA helicase MCM PF00493.23 OEU11094.1 - 0.00018 20.7 0.1 0.86 8.7 0.0 3.4 3 0 0 3 3 3 2 MCM P-loop domain AAA_19 PF13245.6 OEU11094.1 - 0.00037 20.9 2.9 0.28 11.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 OEU11094.1 - 0.00078 19.4 0.6 28 4.6 0.0 5.3 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_24 PF13479.6 OEU11094.1 - 0.0016 18.2 0.4 8.8 6.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain BRE1 PF08647.11 OEU11094.1 - 0.0017 18.4 4.2 0.0017 18.4 4.2 3.0 2 0 0 2 2 1 1 BRE1 E3 ubiquitin ligase zf-C4H2 PF10146.9 OEU11094.1 - 0.0017 18.7 1.5 0.0017 18.7 1.5 2.5 2 0 0 2 2 2 1 Zinc finger-containing protein Sigma54_activat PF00158.26 OEU11094.1 - 0.0022 17.7 0.0 4.1 7.1 0.0 3.6 3 0 0 3 3 3 0 Sigma-54 interaction domain APG6_N PF17675.1 OEU11094.1 - 0.0031 18.0 2.2 0.0031 18.0 2.2 3.5 3 0 0 3 3 2 1 Apg6 coiled-coil region TsaE PF02367.17 OEU11094.1 - 0.0035 17.3 3.4 0.87 9.6 0.0 4.3 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ADIP PF11559.8 OEU11094.1 - 0.004 17.2 1.8 0.004 17.2 1.8 2.9 2 0 0 2 2 1 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 OEU11094.1 - 0.0045 17.0 3.0 0.0045 17.0 3.0 4.2 2 2 0 2 2 2 1 TPR/MLP1/MLP2-like protein IstB_IS21 PF01695.17 OEU11094.1 - 0.0055 16.5 2.4 1.4 8.6 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein Seryl_tRNA_N PF02403.22 OEU11094.1 - 0.0067 16.6 2.2 0.0067 16.6 2.2 3.7 3 0 0 3 3 1 1 Seryl-tRNA synthetase N-terminal domain RuvB_N PF05496.12 OEU11094.1 - 0.0079 16.0 0.1 1.6 8.5 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 OEU11094.1 - 0.0095 15.7 0.2 15 5.4 0.0 3.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OEU11094.1 - 0.019 14.6 2.1 0.28 10.8 0.0 3.4 3 1 1 4 4 2 0 AAA domain Zeta_toxin PF06414.12 OEU11094.1 - 0.025 13.8 0.6 1.9 7.8 0.0 3.8 4 0 0 4 4 4 0 Zeta toxin AAA_13 PF13166.6 OEU11094.1 - 0.03 13.0 19.2 0.059 12.0 1.1 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OEU11094.1 - 0.039 14.2 3.7 47 4.2 0.3 4.6 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Fez1 PF06818.15 OEU11094.1 - 0.04 14.4 21.0 0.1 13.0 0.7 2.8 2 0 0 2 2 2 0 Fez1 MMR_HSR1 PF01926.23 OEU11094.1 - 0.098 12.7 0.1 0.67 10.1 0.0 2.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 OEU11094.1 - 0.13 11.6 6.8 1.8 7.9 0.1 4.0 4 1 1 5 5 4 0 Magnesium chelatase, subunit ChlI ATG16 PF08614.11 OEU11094.1 - 0.3 11.3 33.8 0.034 14.4 4.6 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 OEU11094.1 - 0.3 10.4 33.9 0.31 10.4 5.6 2.7 2 0 0 2 2 2 0 Tropomyosin DUF4795 PF16043.5 OEU11094.1 - 0.31 10.6 24.1 0.084 12.5 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) AAA_28 PF13521.6 OEU11094.1 - 0.5 10.6 7.0 36 4.6 0.0 4.2 4 0 0 4 4 3 0 AAA domain FAM76 PF16046.5 OEU11094.1 - 0.65 9.3 17.3 1.1 8.6 10.9 2.5 2 0 0 2 2 2 0 FAM76 protein Atg14 PF10186.9 OEU11094.1 - 0.66 9.0 22.6 0.012 14.8 0.6 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 OEU11094.1 - 0.81 9.0 26.1 0.011 15.1 1.8 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 OEU11094.1 - 0.98 8.9 15.0 9.1 5.7 0.1 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_11 PF13086.6 OEU11094.1 - 1 9.1 19.7 1 9.1 0.0 4.5 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 OEU11094.1 - 1.4 8.9 7.7 4.4 7.2 0.0 4.4 5 0 0 5 5 3 0 NACHT domain V_ATPase_I PF01496.19 OEU11094.1 - 1.9 6.3 14.0 1.2 6.9 6.4 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FapA PF03961.13 OEU11094.1 - 2.1 6.8 17.1 1.4 7.4 2.0 2.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 OEU11094.1 - 2.2 7.4 26.7 0.068 12.4 0.5 2.8 3 0 0 3 3 3 0 TMPIT-like protein ERM PF00769.19 OEU11094.1 - 2.8 7.7 32.3 2 8.2 2.9 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SHE3 PF17078.5 OEU11094.1 - 2.9 7.5 23.1 0.022 14.5 2.6 2.6 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 SKA1 PF07160.12 OEU11094.1 - 3.3 7.5 17.1 2.5 7.9 1.0 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ABC_tran PF00005.27 OEU11094.1 - 3.4 8.2 13.2 4.9 7.7 0.0 5.0 6 0 0 6 6 3 0 ABC transporter Spc7 PF08317.11 OEU11094.1 - 3.7 6.3 37.8 0.036 12.9 3.7 2.9 3 0 0 3 3 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 OEU11094.1 - 4.4 6.7 27.3 6 6.2 16.5 2.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 Occludin_ELL PF07303.13 OEU11094.1 - 5.8 7.7 13.9 2 9.2 0.1 4.1 2 1 1 3 3 2 0 Occludin homology domain Laminin_II PF06009.12 OEU11094.1 - 7.1 6.6 19.1 0.47 10.5 1.1 3.7 3 0 0 3 3 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 OEU11094.1 - 9.5 6.3 7.1 3.3 7.8 0.0 3.4 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Borrelia_P83 PF05262.11 OEU11094.1 - 9.8 4.5 17.1 0.067 11.7 8.4 1.6 2 0 0 2 2 1 0 Borrelia P83/100 protein ASFV_J13L PF05568.11 OEU11095.1 - 0.008 15.9 0.2 0.008 15.9 0.2 2.0 2 0 0 2 2 2 1 African swine fever virus J13L protein GNVR PF13807.6 OEU11095.1 - 0.95 9.4 0.0 0.95 9.4 0.0 3.3 5 0 0 5 5 5 0 G-rich domain on putative tyrosine kinase DUF1189 PF06691.11 OEU11096.1 - 0.089 12.3 2.5 0.14 11.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Myb_DNA-binding PF00249.31 OEU11099.1 - 3.2e-10 40.0 0.1 3e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU11099.1 - 0.00012 22.2 0.0 0.072 13.3 0.0 2.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU11099.1 - 0.0019 18.1 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 Myb DNA-binding like PT PF04886.12 OEU11102.1 - 0.0014 18.1 2.6 0.0014 18.1 2.6 7.3 2 1 3 5 5 5 2 PT repeat IF3_C PF00707.22 OEU11102.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain ShK PF01549.24 OEU11102.1 - 0.62 10.6 21.1 0.26 11.9 3.5 3.7 3 1 1 4 4 4 0 ShK domain-like MatE PF01554.18 OEU11103.1 - 9.2e-10 38.4 10.7 1.3e-09 37.9 10.7 1.2 1 0 0 1 1 1 1 MatE Trehalose_PPase PF02358.16 OEU11104.1 - 1e-44 152.4 0.0 1.6e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Neil1-DNA_bind PF09292.10 OEU11105.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind DUF4126 PF13548.6 OEU11106.1 - 7.9e-29 100.6 17.3 2.7e-14 53.2 1.6 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4126) DUF4834 PF16118.5 OEU11106.1 - 0.31 12.0 3.2 0.35 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TRAP_alpha PF03896.16 OEU11108.1 - 0.092 11.9 0.8 0.11 11.7 0.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit IL12 PF03039.14 OEU11108.1 - 0.11 11.8 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Histone_H2A_C PF16211.5 OEU11109.1 - 7e-22 76.9 0.9 1.3e-21 76.0 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OEU11109.1 - 2.3e-14 53.9 0.0 3.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OEU11109.1 - 0.00083 19.6 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_tran PF00005.27 OEU11111.1 - 6e-40 136.9 0.1 7.4e-25 88.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OEU11111.1 - 7.9e-40 137.2 18.4 4e-26 92.3 7.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OEU11111.1 - 3.2e-08 33.3 2.6 0.85 9.0 0.0 4.4 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU11111.1 - 4.4e-07 30.3 0.3 0.0018 18.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OEU11111.1 - 5e-07 29.8 1.2 0.0017 18.3 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 OEU11111.1 - 1.9e-06 28.4 0.8 0.0025 18.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU11111.1 - 6.6e-06 25.8 0.3 0.018 14.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OEU11111.1 - 2.8e-05 24.2 1.2 0.53 10.4 0.1 3.8 5 0 0 5 5 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OEU11111.1 - 5.8e-05 23.7 1.0 0.042 14.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OEU11111.1 - 0.00013 21.8 1.1 1.9 8.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 OEU11111.1 - 0.0016 18.5 1.5 0.24 11.4 0.0 3.7 4 0 0 4 4 3 1 Dynamin family RNA_helicase PF00910.22 OEU11111.1 - 0.0026 18.1 0.0 0.22 11.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase SbcCD_C PF13558.6 OEU11111.1 - 0.0033 17.6 0.2 2.6 8.3 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 OEU11111.1 - 0.0033 16.9 0.1 0.31 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DEAD PF00270.29 OEU11111.1 - 0.005 16.6 1.1 0.62 9.8 0.0 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase cobW PF02492.19 OEU11111.1 - 0.0088 15.6 2.1 0.011 15.3 0.0 2.2 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OEU11111.1 - 0.015 15.8 0.0 3 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OEU11111.1 - 0.019 14.0 0.2 0.14 11.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OEU11111.1 - 0.02 14.6 0.8 3.2 7.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OEU11111.1 - 0.022 14.5 0.2 13 5.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 OEU11111.1 - 0.026 14.7 0.2 0.11 12.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 OEU11111.1 - 0.046 13.3 0.2 11 5.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.11 OEU11111.1 - 0.053 12.4 0.0 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain TsaE PF02367.17 OEU11111.1 - 0.063 13.3 0.2 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 OEU11111.1 - 0.066 13.6 0.1 3.5 8.1 0.0 3.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 OEU11111.1 - 0.077 12.6 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 OEU11111.1 - 0.1 12.7 0.8 0.97 9.5 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Septin PF00735.18 OEU11111.1 - 0.12 11.7 0.1 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Septin Rad17 PF03215.15 OEU11111.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 OEU11111.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cupin_3 PF05899.12 OEU11113.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pkinase PF00069.25 OEU11115.1 - 1e-51 175.9 0.1 1.2e-51 175.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU11115.1 - 3.7e-20 72.3 0.0 4.6e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU11115.1 - 2.8e-05 23.6 0.0 5.6e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 OEU11115.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL STPPase_N PF16891.5 OEU11115.1 - 0.12 12.8 0.1 0.44 11.0 0.1 2.0 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Flavodoxin_1 PF00258.25 OEU11116.1 - 3.1e-08 33.9 0.5 1.2e-07 32.1 0.4 2.0 1 1 0 1 1 1 1 Flavodoxin DUF1926 PF09095.11 OEU11116.1 - 0.021 14.5 0.1 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) GlcNAc PF11397.8 OEU11117.1 - 1.1e-58 199.3 0.7 8.8e-51 173.4 0.5 2.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 OEU11117.1 - 6.3e-05 22.8 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 RVT_1 PF00078.27 OEU11118.1 - 0.00019 21.0 0.0 0.00061 19.4 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU11118.1 - 0.0016 18.0 0.1 0.0042 16.6 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU11118.1 - 0.15 12.8 1.1 0.56 11.0 1.1 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-MYND PF01753.18 OEU11119.1 - 2.1e-07 30.9 13.4 5.6e-07 29.5 13.4 1.8 1 0 0 1 1 1 1 MYND finger GcnA_N PF18229.1 OEU11119.1 - 0.0015 18.5 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 N-acetyl-beta-D-glucosaminidase N-terminal domain DUF3146 PF11344.8 OEU11119.1 - 0.14 11.8 0.1 0.75 9.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3146) TPR_2 PF07719.17 OEU11119.1 - 0.15 12.3 0.4 1.9 8.8 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Alpha_kinase PF02816.18 OEU11120.1 - 5.1e-31 108.2 0.1 7.1e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family TIG PF01833.24 OEU11120.1 - 0.25 11.4 1.5 4.3 7.5 0.5 2.5 2 0 0 2 2 2 0 IPT/TIG domain ABC_tran PF00005.27 OEU11121.1 - 1.1e-28 100.5 9.0 9.8e-17 61.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU11121.1 - 4.6e-10 39.8 22.7 1.3e-06 28.5 0.3 4.5 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU11121.1 - 1.7e-06 27.7 16.7 0.0027 17.2 0.6 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU11121.1 - 1.9e-05 25.0 0.3 0.065 13.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 OEU11121.1 - 7.9e-05 23.1 1.6 0.06 13.8 0.2 3.8 3 1 1 4 4 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OEU11121.1 - 0.00016 21.6 0.0 0.065 13.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 OEU11121.1 - 0.00064 19.4 0.1 0.38 10.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OEU11121.1 - 0.00089 19.0 1.2 2 8.1 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein SbcCD_C PF13558.6 OEU11121.1 - 0.0012 19.0 0.0 12 6.2 0.1 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 OEU11121.1 - 0.0019 18.6 7.3 0.063 13.7 0.0 3.5 4 0 0 4 4 4 2 RNA helicase AAA_18 PF13238.6 OEU11121.1 - 0.0034 17.9 8.0 0.63 10.6 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_33 PF13671.6 OEU11121.1 - 0.0042 17.3 0.1 4.3 7.5 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OEU11121.1 - 0.0061 16.2 1.5 26 4.3 0.1 3.8 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 OEU11121.1 - 0.0087 15.8 0.2 0.27 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 OEU11121.1 - 0.024 13.9 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 OEU11121.1 - 0.056 13.3 0.2 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 OEU11121.1 - 0.06 13.6 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OEU11121.1 - 0.093 12.4 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OEU11121.1 - 0.095 12.8 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 OEU11121.1 - 0.16 12.4 1.8 11 6.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF4834 PF16118.5 OEU11122.1 - 1.4 10.0 0.0 1.4 10.0 0.0 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4834) TPR_2 PF07719.17 OEU11123.1 - 0.015 15.4 0.3 7.5 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU11123.1 - 0.027 14.5 4.5 1.2 9.3 0.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat VasI PF11319.8 OEU11123.1 - 0.06 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Nucleotid_trans PF03407.16 OEU11124.1 - 1.4e-06 28.4 0.9 1.4e-06 28.4 0.9 3.0 3 0 0 3 3 3 1 Nucleotide-diphospho-sugar transferase DUF3671 PF12420.8 OEU11124.1 - 0.28 11.3 1.4 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function LRR_8 PF13855.6 OEU11125.1 - 3.8e-21 74.6 24.0 8.6e-10 38.2 3.0 4.2 2 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OEU11125.1 - 1.5e-20 72.9 24.7 9.7e-05 22.7 1.6 5.3 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11125.1 - 1.2e-12 46.5 19.7 0.069 13.7 0.0 8.7 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.6 OEU11125.1 - 2.8e-05 23.8 20.1 0.14 12.2 0.0 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.6 OEU11125.1 - 0.016 14.7 5.0 0.31 10.5 0.4 2.8 1 1 2 3 3 3 0 Leucine-rich repeat DpnI_C PF17726.1 OEU11125.1 - 0.04 14.0 1.1 0.58 10.3 0.1 2.9 2 1 1 3 3 3 0 Dam-replacing HTH domain DUF1180 PF06679.12 OEU11126.1 - 0.071 13.5 0.3 0.099 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4698 PF15769.5 OEU11126.1 - 0.55 9.2 5.5 0.61 9.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Macoilin PF09726.9 OEU11126.1 - 7.9 4.9 9.3 7.5 5.0 9.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF285 PF03382.14 OEU11127.1 - 3.2e-60 201.2 28.4 2.3e-32 111.3 10.0 2.7 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Prok_Ub PF14454.6 OEU11127.1 - 0.25 11.0 0.8 1.1e+02 2.6 0.0 4.1 3 2 1 4 4 4 0 Prokaryotic Ubiquitin Peptidase_S10 PF00450.22 OEU11130.1 - 8e-11 42.0 0.0 8.8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PPR_1 PF12854.7 OEU11131.1 - 6.9e-12 44.9 9.3 7.3e-05 22.4 0.0 6.0 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 OEU11131.1 - 1e-11 44.8 6.4 0.0002 21.5 0.2 6.2 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 OEU11131.1 - 3.6e-08 33.4 8.5 0.00019 21.4 0.1 5.6 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 OEU11131.1 - 1.2e-05 25.3 5.5 0.0028 17.8 0.0 4.9 5 0 0 5 5 5 2 PPR repeat LRR_8 PF13855.6 OEU11132.1 - 9.8e-11 41.3 16.6 0.0087 15.8 0.1 6.7 5 2 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 OEU11132.1 - 9.6e-09 35.4 24.3 0.0074 16.7 0.1 7.0 6 1 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OEU11132.1 - 0.00018 21.0 2.8 0.61 9.6 0.1 3.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 OEU11132.1 - 0.22 11.6 8.2 22 5.4 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich repeat UPF0239 PF06783.11 OEU11133.1 - 0.0093 16.1 3.0 0.02 15.1 3.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) Peptidase_S49_N PF08496.10 OEU11133.1 - 0.082 13.0 1.2 0.11 12.6 1.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.9 OEU11133.1 - 0.9 9.1 24.7 4.2 6.9 25.6 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OEU11133.1 - 1.3 9.7 14.4 2.3 9.0 14.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Yae1_N PF09811.9 OEU11134.1 - 0.00026 20.6 22.4 0.012 15.3 0.2 5.8 4 2 1 5 5 5 5 Essential protein Yae1, N terminal DUF3494 PF11999.8 OEU11137.1 - 1.5e-43 148.9 6.8 1.7e-43 148.7 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF2572 PF10833.8 OEU11137.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Yae1_N PF09811.9 OEU11138.1 - 2.3e-14 52.8 63.3 0.054 13.2 0.0 15.6 4 1 5 10 10 10 6 Essential protein Yae1, N terminal Gly-zipper_YMGG PF13441.6 OEU11138.1 - 0.018 14.8 8.5 0.018 14.8 8.5 7.1 4 2 2 6 6 6 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 OEU11138.1 - 0.17 11.9 61.7 0.061 13.3 11.0 7.9 3 2 3 6 6 6 0 Glycine zipper DUF456 PF04306.13 OEU11138.1 - 2 8.7 42.8 0.5 10.6 3.4 5.3 1 1 3 5 5 5 0 Protein of unknown function (DUF456) Transgly_assoc PF04226.13 OEU11138.1 - 4.6 7.6 52.3 29 5.0 1.2 11.4 2 2 7 9 9 9 0 Transglycosylase associated protein 6PGD PF00393.19 OEU11139.1 - 2.8e-122 407.6 0.1 3.4e-122 407.4 0.1 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OEU11139.1 - 1e-44 152.5 0.0 1.6e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OEU11139.1 - 0.0035 17.9 0.7 0.021 15.4 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OEU11139.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGK PF00162.19 OEU11139.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase adh_short PF00106.25 OEU11139.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ECH_1 PF00378.20 OEU11143.1 - 1.1e-33 116.7 0.1 1.1e-19 70.7 0.3 2.6 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU11143.1 - 5e-22 78.8 0.0 1.5e-18 67.4 0.0 3.1 2 2 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Meth_synt_2 PF01717.18 OEU11144.1 - 9.8e-145 481.8 0.0 1.3e-135 451.8 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OEU11144.1 - 1.1e-79 268.2 0.0 2.2e-72 244.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 OEU11144.1 - 0.064 13.0 2.7 0.056 13.2 0.7 2.1 2 0 0 2 2 2 0 Short C-terminal domain BUD22 PF09073.10 OEU11145.1 - 0.00086 18.8 49.1 0.0011 18.4 49.1 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 OEU11145.1 - 9.9 4.2 48.1 12 3.9 48.1 1.2 1 0 0 1 1 1 0 Nop14-like family XFP_C PF09363.10 OEU11147.1 - 0.005 16.3 0.0 0.0063 16.0 0.0 1.1 1 0 0 1 1 1 1 XFP C-terminal domain CEND1 PF15677.5 OEU11147.1 - 0.021 15.4 0.0 0.025 15.1 0.0 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 ADH_N PF08240.12 OEU11147.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Tmemb_14 PF03647.13 OEU11148.1 - 2.8e-25 88.9 9.0 3.2e-25 88.7 9.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gram_pos_anchor PF00746.21 OEU11148.1 - 0.15 12.0 8.4 1.3 9.1 0.0 3.2 3 0 0 3 3 3 0 LPXTG cell wall anchor motif COX14 PF14880.6 OEU11148.1 - 4 7.4 4.5 19 5.2 0.3 2.5 2 1 1 3 3 3 0 Cytochrome oxidase c assembly TPR_11 PF13414.6 OEU11149.1 - 2.5e-07 30.2 0.0 4.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 OEU11149.1 - 4.8e-05 23.3 2.8 0.26 11.6 0.2 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU11149.1 - 5.2e-05 23.0 0.7 0.46 10.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11149.1 - 0.00022 20.9 1.1 0.99 9.3 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU11149.1 - 0.0015 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU11149.1 - 0.016 15.1 0.0 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OEU11149.1 - 0.038 14.4 0.4 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU11149.1 - 0.051 13.8 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OEU11149.1 - 0.072 13.9 0.0 4.6 8.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU11149.1 - 0.12 12.7 0.0 29 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 OEU11150.1 - 8.7e-12 45.1 1.5 3e-11 43.4 0.6 2.0 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 OEU11150.1 - 6.6e-08 32.3 2.9 1.3e-07 31.4 2.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU11150.1 - 0.00019 21.0 1.3 0.00043 19.9 0.3 1.9 1 1 1 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 OEU11150.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OEU11150.1 - 0.0092 16.7 0.2 0.024 15.3 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU11150.1 - 0.013 15.3 0.3 0.029 14.2 0.3 1.5 1 0 0 1 1 1 0 Methyltransferase domain WRNPLPNID PF15017.6 OEU11150.1 - 0.061 14.2 1.0 0.061 14.2 1.0 2.9 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Pox_Ag35 PF03286.14 OEU11150.1 - 2.5 7.8 14.3 1.9 8.2 4.7 3.2 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DUF4611 PF15387.6 OEU11150.1 - 9.8 6.5 11.1 1.6 9.0 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RNA_pol_N PF01194.17 OEU11151.1 - 0.15 12.4 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit zinc_ribbon_4 PF13717.6 OEU11151.1 - 0.16 11.9 0.5 13 5.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DNA_pol_A_exo1 PF01612.20 OEU11152.1 - 2e-05 24.4 0.0 0.00017 21.3 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease BKACE PF05853.12 OEU11152.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Peptidase_A25 PF03418.14 OEU11152.1 - 0.18 10.7 0.6 0.26 10.2 0.6 1.2 1 0 0 1 1 1 0 Germination protease Cpn10 PF00166.21 OEU11154.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit FAM199X PF15814.5 OEU11156.1 - 0.65 9.0 13.0 2.2 7.3 12.9 1.9 1 1 0 1 1 1 0 Protein family FAM199X DUF2956 PF11169.8 OEU11156.1 - 2.3 8.4 7.7 2.5 8.3 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) zf-MYND PF01753.18 OEU11156.1 - 3.8 7.7 14.4 4.2 7.5 9.2 2.7 1 1 1 2 2 2 0 MYND finger Glyco_tran_28_C PF04101.16 OEU11157.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PHD_3 PF13922.6 OEU11157.1 - 0.19 12.1 0.9 0.63 10.5 0.9 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Herpes_env PF01673.18 OEU11157.1 - 0.34 9.8 5.8 0.02 13.8 0.7 1.5 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein DUF1995 PF09353.10 OEU11158.1 - 3.9e-07 30.3 0.0 1.6e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) Sh_2 PF17512.2 OEU11158.1 - 0.13 12.0 1.8 0.26 11.0 1.8 1.5 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein DUF1514 PF07438.11 OEU11158.1 - 3.1 7.8 6.3 3.5 7.5 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) AF-4 PF05110.13 OEU11159.1 - 0.71 7.9 11.6 0.99 7.4 11.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Trypsin PF00089.26 OEU11162.1 - 5.5e-39 134.3 0.1 6.3e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin Chorion_3 PF05387.11 OEU11163.1 - 0.035 13.8 0.1 0.045 13.4 0.1 1.1 1 0 0 1 1 1 0 Chorion family 3 DUF3603 PF12227.8 OEU11165.1 - 0.0068 15.7 18.6 0.8 9.0 1.2 4.2 1 1 4 5 5 5 5 Protein of unknown function (DUF3603) APG12 PF04110.13 OEU11165.1 - 0.037 14.4 2.4 17 5.9 0.1 3.2 1 1 2 4 4 4 0 Ubiquitin-like autophagy protein Apg12 RasGAP PF00616.19 OEU11165.1 - 0.33 10.6 2.7 26 4.4 0.4 2.9 1 1 3 4 4 4 0 GTPase-activator protein for Ras-like GTPase SDA1 PF05285.12 OEU11166.1 - 0.051 13.0 9.8 0.056 12.9 9.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OEU11166.1 - 0.11 10.7 12.0 0.13 10.5 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 OEU11166.1 - 0.86 9.7 11.7 1.1 9.3 11.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 OEU11166.1 - 3.7 7.4 17.6 3.1 7.6 15.8 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region NCA2 PF08637.10 OEU11167.1 - 2.8e-18 66.1 1.9 3.6e-18 65.8 0.3 2.0 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 Dapper PF15268.6 OEU11168.1 - 0.032 13.1 12.8 0.036 12.9 12.8 1.0 1 0 0 1 1 1 0 Dapper TAF4 PF05236.14 OEU11168.1 - 0.11 12.2 17.4 0.17 11.6 17.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Macoilin PF09726.9 OEU11168.1 - 0.15 10.6 21.2 0.18 10.3 21.2 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 OEU11168.1 - 0.19 10.5 15.6 0.21 10.4 15.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 OEU11168.1 - 0.61 9.6 14.7 0.82 9.2 14.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 OEU11168.1 - 0.94 7.9 15.5 1.1 7.7 15.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Menin PF05053.13 OEU11168.1 - 1.4 7.2 13.2 1.8 6.8 13.2 1.2 1 0 0 1 1 1 0 Menin MCM_bind PF09739.9 OEU11168.1 - 1.9 6.9 14.6 2.9 6.2 14.6 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FAM60A PF15396.6 OEU11168.1 - 2.5 8.1 19.2 3.4 7.6 19.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 OEU11168.1 - 2.8 6.6 17.2 3.5 6.3 17.2 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OEU11168.1 - 3.1 7.5 14.5 4.5 7.0 14.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MAS20 PF02064.15 OEU11168.1 - 4.8 7.3 10.2 7.1 6.7 10.2 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor GREB1 PF15782.5 OEU11168.1 - 6.4 3.7 12.8 7.4 3.5 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 OEU11168.1 - 6.6 5.4 12.7 7.8 5.2 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 OEU11168.1 - 7.1 4.8 20.6 9 4.4 20.6 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.6 OEU11169.1 - 0.00065 19.4 9.4 0.0031 17.3 4.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU11169.1 - 0.00076 19.8 11.0 0.0031 17.9 1.9 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11169.1 - 0.0035 17.7 8.6 3.5 8.5 0.2 4.1 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU11169.1 - 0.22 11.6 11.1 2.9 8.2 0.2 3.9 4 0 0 4 4 4 0 Leucine Rich repeat GTP_EFTU PF00009.27 OEU11170.1 - 2.3e-34 118.7 0.1 1.9e-33 115.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OEU11170.1 - 2.2e-28 99.3 8.8 3.7e-28 98.6 7.3 2.1 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 OEU11170.1 - 3.9e-23 81.3 0.0 1.2e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 OEU11170.1 - 1.8e-20 72.9 0.0 4.9e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 OEU11170.1 - 6.1e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OEU11170.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OEU11170.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GCP5-Mod21 PF14609.6 OEU11170.1 - 0.054 11.8 0.2 0.1 11.0 0.2 1.3 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Dynamin_N PF00350.23 OEU11170.1 - 0.1 12.6 0.0 0.44 10.6 0.0 2.0 1 1 0 1 1 1 0 Dynamin family FHA PF00498.26 OEU11171.1 - 4.3e-07 30.2 0.0 7.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rib_recp_KP_reg PF05104.12 OEU11172.1 - 2.6 9.1 4.5 4.1 8.4 4.5 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region EF-hand_6 PF13405.6 OEU11174.1 - 1.6e-19 68.1 4.3 9.6e-05 22.0 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OEU11174.1 - 1.6e-18 64.8 6.2 6.8e-05 22.1 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OEU11174.1 - 2.7e-18 66.2 2.7 5.5e-08 33.2 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU11174.1 - 1.1e-16 59.5 11.4 4e-05 22.9 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OEU11174.1 - 7.7e-13 48.1 5.1 7.1e-06 25.8 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU11174.1 - 9.6e-07 29.1 3.0 0.00035 20.9 0.1 3.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OEU11174.1 - 0.0026 18.0 0.2 0.75 10.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain Herpes_UL49_5 PF05702.11 OEU11174.1 - 0.025 14.6 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Sulfate_transp PF00916.20 OEU11175.1 - 1.8e-30 106.0 17.5 1.8e-30 106.0 17.5 1.8 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 OEU11175.1 - 6.5e-08 32.2 0.1 1.3e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OEU11175.1 - 2.3 8.6 22.0 0.39 11.1 2.3 3.3 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily US6 PF17616.2 OEU11176.1 - 0.38 10.7 2.2 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Viral unique short region 6 FliP PF00813.20 OEU11177.1 - 0.13 12.2 0.5 0.19 11.6 0.5 1.4 1 0 0 1 1 1 0 FliP family Enterotoxin_HS1 PF08090.11 OEU11177.1 - 0.59 10.1 4.5 0.59 10.1 2.1 2.0 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Rotamase PF00639.21 OEU11177.1 - 3.8 8.5 11.1 4.7 8.2 2.0 2.3 1 1 1 2 2 2 0 PPIC-type PPIASE domain zf-RING_2 PF13639.6 OEU11178.1 - 1.8e-09 37.7 13.2 4.6e-09 36.5 13.2 1.7 1 0 0 1 1 1 1 Ring finger domain IQ PF00612.27 OEU11178.1 - 1.1e-07 31.0 2.8 0.0015 18.1 0.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif zf-C3HC4 PF00097.25 OEU11178.1 - 3e-06 27.0 10.0 3e-06 27.0 10.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU11178.1 - 6.8e-06 25.9 11.9 1.4e-05 24.9 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU11178.1 - 0.00025 20.8 13.0 0.00025 20.8 13.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU11178.1 - 0.0019 18.4 10.6 0.0019 18.4 10.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OEU11178.1 - 0.0024 17.6 14.5 0.005 16.6 14.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OEU11178.1 - 0.0027 17.7 6.3 0.0054 16.8 6.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OEU11178.1 - 0.0036 17.3 11.7 0.0038 17.2 5.4 2.6 1 1 1 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.6 OEU11178.1 - 0.25 11.2 14.1 0.14 12.0 11.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OEU11178.1 - 2.1 8.6 14.7 3.3 7.9 13.5 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 OEU11178.1 - 6.8 7.1 12.9 0.69 10.3 1.9 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CENP-B_dimeris PF09026.10 OEU11179.1 - 0.01 16.2 8.5 0.39 11.1 1.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3824 PF12868.7 OEU11179.1 - 0.11 13.2 0.5 0.11 13.2 0.5 3.1 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) Mis12 PF05859.12 OEU11179.1 - 0.48 10.5 11.5 0.26 11.3 7.4 2.7 2 1 0 2 2 2 0 Mis12 protein Ribosomal_60s PF00428.19 OEU11179.1 - 0.48 11.1 0.1 0.48 11.1 0.1 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein Ferric_reduct PF01794.19 OEU11180.1 - 2.5e-15 56.7 6.4 2.5e-15 56.7 6.4 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OEU11180.1 - 5.5e-11 42.8 0.1 4.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OEU11180.1 - 5.1e-07 29.8 0.0 1.9e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OEU11180.1 - 0.12 13.0 0.0 7 7.4 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain MIP PF00230.20 OEU11181.1 - 6.4e-55 186.3 16.8 7.1e-55 186.2 16.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Fasciclin PF02469.22 OEU11182.1 - 4.8e-30 104.4 0.0 6.8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Herpes_LMP1 PF05297.11 OEU11182.1 - 1.4 8.0 13.4 1.9 7.6 13.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ABC2_membrane PF01061.24 OEU11185.1 - 2.9e-31 108.5 16.3 3.9e-31 108.1 16.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OEU11185.1 - 2.4e-20 73.4 0.2 2.4e-20 73.4 0.2 1.9 2 0 0 2 2 2 1 ABC transporter PAF PF15715.5 OEU11185.1 - 0.035 14.7 5.2 0.081 13.5 5.2 1.6 1 0 0 1 1 1 0 PCNA-associated factor histone like domain DUF373 PF04123.13 OEU11185.1 - 1.6 8.1 5.7 2.5 7.4 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.25 OEU11186.1 - 3.8e-37 128.1 0.1 6.7e-37 127.3 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU11186.1 - 3.9e-13 49.3 0.2 3.4e-11 42.9 0.1 3.4 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OEU11186.1 - 0.0048 16.8 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU11186.1 - 0.031 13.9 0.5 0.059 13.0 0.1 1.6 2 0 0 2 2 2 0 RIO1 family PAP2_C PF14360.6 OEU11187.1 - 3e-09 37.3 7.1 3e-09 37.3 7.1 2.0 2 1 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 OEU11187.1 - 6.1e-09 35.8 3.6 7.8e-09 35.5 3.6 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 OEU11187.1 - 7.4e-05 22.5 1.0 7.4e-05 22.5 1.0 1.8 2 1 0 2 2 2 1 PAP2 superfamily Armet PF10208.9 OEU11188.1 - 0.0079 16.1 1.9 0.012 15.5 1.9 1.4 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Mago_nashi PF02792.14 OEU11188.1 - 0.072 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Mago nashi protein TMEM171 PF15471.6 OEU11188.1 - 0.21 10.6 2.8 0.25 10.3 2.8 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Piezo_RRas_bdg PF12166.8 OEU11188.1 - 0.27 10.5 4.5 0.32 10.2 4.5 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Presenilin PF01080.17 OEU11188.1 - 5.9 5.5 6.7 6.1 5.5 6.7 1.1 1 0 0 1 1 1 0 Presenilin HA PF03457.14 OEU11191.1 - 3.4e-21 75.3 0.3 2.1e-09 37.6 0.0 3.0 3 0 0 3 3 3 2 Helicase associated domain Sulfotransfer_2 PF03567.14 OEU11191.1 - 3.9e-05 23.7 12.1 3.9e-05 23.7 12.1 3.0 3 1 0 3 3 3 1 Sulfotransferase family DUF3446 PF11928.8 OEU11191.1 - 1.7 9.0 19.3 1.1 9.6 4.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Dsh_C PF12316.8 OEU11191.1 - 2.4 8.5 13.9 7 7.0 4.7 3.0 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Pap_E4 PF02711.14 OEU11191.1 - 7.9 7.5 14.5 9.9 7.2 2.9 3.6 2 1 1 3 3 3 0 E4 protein ATP-grasp_2 PF08442.10 OEU11192.1 - 2.5e-45 154.6 0.0 1.6e-44 151.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OEU11192.1 - 3.9e-17 62.5 0.2 6.5e-17 61.8 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OEU11192.1 - 0.00025 20.5 0.0 0.033 13.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Sulfotransfer_3 PF13469.6 OEU11193.1 - 0.0018 18.7 0.0 0.0057 17.1 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family IGPS PF00218.21 OEU11195.1 - 1.5e-07 30.9 0.9 2.5e-07 30.1 0.9 1.5 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase Desulfoferrod_N PF06397.12 OEU11196.1 - 0.01 15.5 5.8 1.2 8.8 0.1 3.7 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Nop14 PF04147.12 OEU11196.1 - 5.4 5.1 7.4 7.4 4.6 7.4 1.0 1 0 0 1 1 1 0 Nop14-like family Bestrophin PF01062.21 OEU11197.1 - 1.2e-16 61.0 0.6 7.5e-11 42.0 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SelK_SelG PF10961.8 OEU11197.1 - 0.16 12.6 5.7 3.2 8.4 0.3 3.6 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Dirigent PF03018.14 OEU11198.1 - 0.0039 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Dirigent-like protein TPR_12 PF13424.6 OEU11200.1 - 1.1e-15 57.6 11.4 6.9e-09 35.9 1.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU11200.1 - 1e-11 44.3 6.1 0.00092 19.0 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU11200.1 - 2.2e-09 36.8 4.9 0.43 10.9 0.1 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU11200.1 - 9.1e-08 31.7 11.9 0.065 13.4 0.3 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11200.1 - 3e-06 26.8 9.6 0.01 15.6 0.4 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU11200.1 - 6.5e-05 22.6 0.8 9.7e-05 22.0 0.8 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_7 PF13176.6 OEU11200.1 - 0.0005 19.9 5.1 23 5.3 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU11200.1 - 0.0029 18.2 0.1 21 5.9 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU11200.1 - 0.028 15.2 1.6 8.9 7.4 0.1 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OEU11200.1 - 0.032 13.9 1.6 48 3.8 0.1 4.4 4 0 0 4 4 4 0 TPR repeat SARS_lipid_bind PF09399.10 OEU11200.1 - 0.083 13.1 0.3 0.66 10.2 0.0 2.3 3 0 0 3 3 3 0 SARS lipid binding protein MCM PF00493.23 OEU11203.1 - 3.7e-100 333.6 0.1 5.3e-100 333.1 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OEU11203.1 - 2.9e-37 127.3 0.1 6e-37 126.3 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OEU11203.1 - 6.7e-25 87.3 1.0 1.4e-24 86.3 1.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OEU11203.1 - 7.4e-08 32.0 0.0 6.6e-07 28.9 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 OEU11203.1 - 3.3e-07 30.8 0.2 1.4e-06 28.8 0.2 2.1 1 1 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OEU11203.1 - 4.1e-05 23.6 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OEU11203.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OEU11203.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-RVT PF13966.6 OEU11204.1 - 9e-07 29.5 0.5 3.1e-06 27.8 0.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_3 PF13456.6 OEU11204.1 - 0.0082 16.0 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like HDC PF02329.16 OEU11204.1 - 0.031 13.3 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain Galactosyl_T PF01762.21 OEU11205.1 - 0.048 13.5 1.2 0.21 11.4 0.3 2.0 2 0 0 2 2 2 0 Galactosyltransferase AbiGii_2 PF16873.5 OEU11205.1 - 0.092 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGii toxin Globin PF00042.22 OEU11206.1 - 1.2e-10 41.9 0.0 1.6e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Globin Pkinase PF00069.25 OEU11207.1 - 5.5e-18 65.3 0.0 6.5e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU11207.1 - 1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 OEU11207.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 HA PF03457.14 OEU11208.1 - 2.5e-22 78.9 3.6 3.4e-11 43.3 0.3 2.6 2 0 0 2 2 2 2 Helicase associated domain HTH_Tnp_Mu_1 PF02316.16 OEU11208.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.9 3 0 0 3 3 3 0 Mu DNA-binding domain Snf7 PF03357.21 OEU11209.1 - 0.025 14.2 0.4 0.025 14.2 0.4 1.6 2 0 0 2 2 2 0 Snf7 Gly_transf_sug PF04488.15 OEU11210.1 - 2.4e-08 34.5 2.2 1.3e-07 32.2 0.1 2.5 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TRM13 PF05206.14 OEU11210.1 - 0.018 14.6 3.3 0.12 11.9 0.7 2.6 3 0 0 3 3 3 0 Methyltransferase TRM13 Ctr PF04145.15 OEU11210.1 - 0.31 11.7 0.0 0.31 11.7 0.0 2.3 2 1 0 2 2 2 0 Ctr copper transporter family HMG_box PF00505.19 OEU11211.1 - 3.4e-09 37.0 2.0 3.4e-09 37.0 2.0 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU11211.1 - 4.1e-05 24.1 1.0 0.00012 22.6 1.0 1.9 1 0 0 1 1 1 1 HMG-box domain JmjC PF02373.22 OEU11211.1 - 0.011 16.1 0.0 0.055 13.9 0.0 2.2 1 1 0 1 1 1 0 JmjC domain, hydroxylase DUF1492 PF07374.11 OEU11211.1 - 0.016 15.4 0.6 0.046 13.9 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) AraC_binding PF02311.19 OEU11211.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Kelch_2 PF07646.15 OEU11212.1 - 0.11 12.5 0.0 0.4 10.7 0.0 2.0 1 1 0 1 1 1 0 Kelch motif DUF5308 PF17233.2 OEU11212.1 - 0.14 12.3 8.1 0.28 11.4 8.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5308) DUF285 PF03382.14 OEU11213.1 - 1.2e-39 134.8 16.6 1.6e-31 108.6 7.5 2.8 2 1 1 3 3 3 2 Mycoplasma protein of unknown function, DUF285 YadA_head PF05658.14 OEU11213.1 - 0.0005 20.4 2.5 0.0036 17.7 0.2 3.3 3 1 0 3 3 3 1 Head domain of trimeric autotransporter adhesin DUF1325 PF07039.11 OEU11213.1 - 0.015 15.4 1.0 0.59 10.2 0.3 2.3 1 1 1 2 2 2 0 SGF29 tudor-like domain Sugar_tr PF00083.24 OEU11215.1 - 6.1e-09 35.3 1.2 4.7e-08 32.3 1.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU11215.1 - 7.4e-07 28.4 3.1 7.4e-07 28.4 3.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Tetraspanin PF00335.20 OEU11215.1 - 0.031 14.0 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Tetraspanin family PT PF04886.12 OEU11217.1 - 4.4e-08 32.5 31.3 2.4 7.8 31.3 3.3 1 1 0 1 1 1 1 PT repeat Desulfoferrod_N PF06397.12 OEU11217.1 - 0.39 10.4 1.8 5 6.8 0.0 2.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF333 PF03891.15 OEU11218.1 - 0.0039 17.4 0.5 0.082 13.1 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF333) Sulfotransfer_4 PF17784.1 OEU11219.1 - 1.5e-05 25.0 0.0 6.4e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU11219.1 - 0.0026 18.2 0.1 3.5 8.0 0.0 2.8 2 1 1 3 3 3 2 Sulfotransferase family FXR_C1 PF16096.5 OEU11219.1 - 5.6 7.2 8.0 1.6 9.0 1.6 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Lipase_3 PF01764.25 OEU11220.1 - 4.4e-10 39.6 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF1958 PF09211.10 OEU11220.1 - 0.053 13.8 0.2 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) Abhydrolase_6 PF12697.7 OEU11220.1 - 0.18 12.4 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family THF_DHG_CYH_C PF02882.19 OEU11221.1 - 1.7e-40 138.0 0.2 2.1e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OEU11221.1 - 1.7e-07 31.5 0.1 2.9e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ADH_zinc_N PF00107.26 OEU11221.1 - 0.029 14.3 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2099 PF09872.9 OEU11221.1 - 0.046 12.9 0.3 1.2 8.2 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) AdoHcyase_NAD PF00670.21 OEU11221.1 - 0.069 13.2 0.2 0.5 10.4 0.2 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 OEU11221.1 - 0.077 13.4 0.2 0.21 12.0 0.2 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Guanylate_cyc PF00211.20 OEU11223.1 - 5.1e-45 153.3 0.0 9e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 OEU11223.1 - 3.2e-23 82.7 0.0 6.4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HNOBA PF07701.14 OEU11223.1 - 1.1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Heme NO binding associated Sec3_C_2 PF15278.6 OEU11223.1 - 0.027 14.8 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit MgtC PF02308.16 OEU11225.1 - 1.3e-35 122.4 4.9 1.4e-35 122.3 4.9 1.0 1 0 0 1 1 1 1 MgtC family Chloroa_b-bind PF00504.21 OEU11226.1 - 1.1e-41 143.0 0.1 3.8e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Acyl_transf_3 PF01757.22 OEU11227.1 - 1.7e-19 70.1 28.4 1.7e-19 70.1 28.4 2.0 2 1 0 2 2 2 1 Acyltransferase family Apis_Csd PF11671.8 OEU11227.1 - 3.4 7.7 10.5 0.14 12.2 3.9 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein Prenyltrans PF00432.21 OEU11229.1 - 7.9e-36 121.5 15.2 4.5e-10 39.1 0.0 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat DUF4666 PF15697.5 OEU11231.1 - 0.091 13.5 2.5 0.25 12.1 2.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) UPF0014 PF03649.13 OEU11234.1 - 5.5e-11 42.3 6.9 6.6e-11 42.0 6.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) HA PF03457.14 OEU11236.1 - 8.5e-75 247.0 26.6 7.1e-16 58.3 0.4 5.0 5 0 0 5 5 5 5 Helicase associated domain Phage_int_SAM_5 PF13102.6 OEU11236.1 - 0.13 12.6 1.6 2.1 8.8 0.0 3.3 3 1 1 4 4 4 0 Phage integrase SAM-like domain Kelch_1 PF01344.25 OEU11236.1 - 0.22 11.1 4.6 7.7 6.2 0.0 3.3 5 0 0 5 5 5 0 Kelch motif DUF4455 PF14643.6 OEU11236.1 - 0.26 9.9 5.6 2.8 6.5 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4455) Kelch_2 PF07646.15 OEU11236.1 - 0.56 10.3 5.3 12 6.1 0.0 3.4 4 0 0 4 4 4 0 Kelch motif DUF2183 PF09949.9 OEU11237.1 - 2.7e-05 24.4 0.1 0.00027 21.2 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) NTNH_C PF08470.10 OEU11237.1 - 0.0071 16.2 0.2 0.0097 15.8 0.2 1.3 1 0 0 1 1 1 1 Nontoxic nonhaemagglutinin C-terminal DUF1521 PF07481.11 OEU11237.1 - 0.038 14.0 0.8 0.28 11.2 0.8 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1521) PrmA PF06325.13 OEU11238.1 - 9.5e-10 38.3 0.8 1.6e-09 37.6 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.16 OEU11238.1 - 3.1e-07 30.4 0.2 5.3e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 OEU11238.1 - 0.00048 19.9 0.1 0.00082 19.2 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 OEU11238.1 - 0.00048 20.0 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU11238.1 - 0.00062 19.4 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OEU11238.1 - 0.0045 17.7 0.0 0.0085 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OEU11238.1 - 0.0096 16.9 0.0 0.02 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OEU11238.1 - 0.013 15.4 0.3 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 Methyltransferase domain SH3-RhoG_link PF16609.5 OEU11239.1 - 0.25 11.1 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region Arf PF00025.21 OEU11240.1 - 2.7e-62 209.3 1.6 3.1e-62 209.1 1.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OEU11240.1 - 3.7e-16 59.4 0.1 5.7e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OEU11240.1 - 9.9e-15 54.5 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OEU11240.1 - 3.9e-12 46.3 0.0 5.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OEU11240.1 - 6.9e-11 41.9 0.4 1.9e-06 27.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OEU11240.1 - 3.1e-10 39.8 0.0 3.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OEU11240.1 - 9.9e-10 38.1 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OEU11240.1 - 3e-05 23.6 0.1 0.00076 19.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OEU11240.1 - 0.00036 20.1 0.2 0.00084 18.9 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OEU11240.1 - 0.045 13.5 0.0 0.59 9.9 0.1 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PPK2 PF03976.14 OEU11240.1 - 0.068 12.7 0.6 0.36 10.3 0.1 2.0 1 1 1 2 2 2 0 Polyphosphate kinase 2 (PPK2) Dynamin_N PF00350.23 OEU11240.1 - 0.073 13.1 0.0 1.6 8.7 0.0 2.1 1 1 1 2 2 2 0 Dynamin family TPR_2 PF07719.17 OEU11241.1 - 3.7e-07 29.8 3.3 0.039 14.1 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU11241.1 - 3.8e-07 30.3 1.5 0.0013 18.9 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU11241.1 - 5.2e-06 26.3 2.6 0.0096 16.1 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU11241.1 - 2e-05 24.3 1.5 0.068 13.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11241.1 - 3.8e-05 23.3 4.4 0.01 15.6 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN6_N PF18055.1 OEU11241.1 - 0.0028 18.0 2.2 0.35 11.2 0.2 2.5 2 1 0 2 2 2 2 26S proteasome regulatory subunit RPN6 N-terminal domain SNAP PF14938.6 OEU11241.1 - 0.0033 16.9 2.4 0.0076 15.7 0.4 2.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 OEU11241.1 - 0.014 14.8 0.0 0.035 13.5 0.0 1.6 1 1 0 1 1 1 0 MalT-like TPR region MIT PF04212.18 OEU11241.1 - 0.03 14.4 0.5 7 6.8 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 OEU11241.1 - 0.068 13.8 1.0 2.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU11241.1 - 0.094 13.6 0.1 37 5.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_lid_9 PF17871.1 OEU11241.1 - 0.11 12.5 1.6 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA lid domain Nucleotid_trans PF03407.16 OEU11242.1 - 1.6e-27 96.9 0.9 2.2e-27 96.4 0.9 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Bestrophin PF01062.21 OEU11243.1 - 9.8e-16 58.0 0.7 3e-11 43.3 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DnaJ PF00226.31 OEU11244.1 - 2.2e-16 59.7 0.2 6e-16 58.3 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain WW PF00397.26 OEU11244.1 - 9.3e-08 32.0 2.1 9.3e-08 32.0 2.1 2.5 2 0 0 2 2 2 1 WW domain CD225 PF04505.12 OEU11244.1 - 1.8e-05 24.8 0.1 0.0003 20.9 0.1 2.5 1 1 0 1 1 1 1 Interferon-induced transmembrane protein YL1 PF05764.13 OEU11244.1 - 0.0068 16.6 10.1 0.37 10.9 6.2 2.2 2 0 0 2 2 2 2 YL1 nuclear protein DUF3223 PF11523.8 OEU11244.1 - 0.077 13.9 0.0 11 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) Connexin PF00029.19 OEU11244.1 - 0.085 12.6 4.5 0.58 9.9 0.0 2.6 3 0 0 3 3 3 0 Connexin SAPS PF04499.15 OEU11244.1 - 3.6 6.2 11.9 4.4 6.0 0.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Orf78 PF06024.12 OEU11244.1 - 8.7 6.7 0.0 8.7 6.7 0.0 5.0 3 2 2 5 5 5 0 Orf78 (ac78) Zip PF02535.22 OEU11244.1 - 8.9 5.4 10.2 71 2.5 9.0 2.2 2 1 0 2 2 2 0 ZIP Zinc transporter PTPRCAP PF15713.5 OEU11246.1 - 0.16 12.3 3.7 0.23 11.8 3.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Glyco_transf_25 PF01755.17 OEU11247.1 - 2.3e-14 53.8 0.0 1.1e-07 31.9 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Pox_P35 PF03213.14 OEU11247.1 - 0.032 13.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus P35 protein SR-25 PF10500.9 OEU11249.1 - 0.098 12.3 1.7 0.15 11.7 1.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPT2 PF08243.11 OEU11249.1 - 9.5 6.8 8.7 1.5 9.4 4.1 1.9 2 0 0 2 2 2 0 SPT2 chromatin protein DUF751 PF05421.11 OEU11252.1 - 0.0056 17.4 0.3 0.0056 17.4 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF751) SLT PF01464.20 OEU11253.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain Bac_transf PF02397.16 OEU11254.1 - 0.039 13.6 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Bacterial sugar transferase DUF5386 PF17360.2 OEU11255.1 - 0.058 13.3 3.9 14 5.5 0.4 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5386) BTB_2 PF02214.22 OEU11258.1 - 1.5e-06 28.4 1.4 2e-05 24.9 1.4 2.7 1 1 0 1 1 1 1 BTB/POZ domain DUF2306 PF10067.9 OEU11259.1 - 3.6e-10 40.2 3.0 6.6e-10 39.4 3.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) PepSY_TM PF03929.16 OEU11259.1 - 0.075 12.7 0.9 0.14 11.8 0.9 1.4 1 0 0 1 1 1 0 PepSY-associated TM region C2 PF00168.30 OEU11261.1 - 0.0097 16.2 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 1 C2 domain Glyco_hydro_17 PF00332.18 OEU11261.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Ctr PF04145.15 OEU11262.1 - 1.9 9.1 7.9 83 3.8 7.8 2.9 2 1 0 2 2 2 0 Ctr copper transporter family Spond_N PF06468.13 OEU11263.1 - 1.9e-32 112.9 0.7 4.1e-32 111.9 0.7 1.5 1 0 0 1 1 1 1 Spondin_N UPF0370 PF13980.6 OEU11263.1 - 0.00039 20.4 4.3 0.0018 18.3 4.3 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0370) PepSY_2 PF13670.6 OEU11263.1 - 0.027 14.5 0.4 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF3124 PF11322.8 OEU11263.1 - 0.21 11.8 2.1 9.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3124) MORN_2 PF07661.13 OEU11263.1 - 3 8.4 7.0 1.1e+02 3.5 0.0 4.4 4 0 0 4 4 4 0 MORN repeat variant DUF3494 PF11999.8 OEU11264.1 - 4.3e-48 163.7 7.9 4.8e-48 163.6 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF4050 PF13259.6 OEU11265.1 - 4.3e-05 23.9 9.4 0.0039 17.5 4.7 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) AT_hook PF02178.19 OEU11267.1 - 4.3e-05 22.9 42.8 0.082 12.8 4.1 5.5 5 0 0 5 5 5 4 AT hook motif DUF3314 PF11771.8 OEU11267.1 - 0.12 12.5 3.6 5.4 7.1 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3314) DUF3439 PF11921.8 OEU11267.1 - 7.7 6.5 21.6 4.2 7.4 9.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GREB1 PF15782.5 OEU11269.1 - 4.9 4.1 19.8 6.4 3.8 19.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fasciclin PF02469.22 OEU11270.1 - 2.2e-20 73.2 0.0 2.6e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Rrp44_CSD1 PF17216.3 OEU11272.1 - 0.034 13.9 2.9 0.076 12.7 2.9 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain MpPF26 PF07666.11 OEU11272.1 - 0.07 13.3 10.1 1.3 9.1 5.9 2.5 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF3671 PF12420.8 OEU11272.1 - 1.2 9.2 5.5 1.4 9.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function ERF PF04404.12 OEU11272.1 - 1.4 8.8 6.6 0.15 11.9 1.6 1.9 2 0 0 2 2 2 0 ERF superfamily DUF1461 PF07314.11 OEU11272.1 - 2.5 8.0 7.7 7.4 6.4 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF2451 PF10474.9 OEU11273.1 - 4.6e-25 88.8 0.1 1.6e-24 87.0 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) PD40 PF07676.12 OEU11274.1 - 0.001 18.9 1.7 0.077 13.0 0.2 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF4875 PF16175.5 OEU11274.1 - 0.011 15.8 0.0 0.6 10.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4875) RXT2_N PF08595.11 OEU11275.1 - 0.48 10.4 4.7 0.13 12.3 0.9 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Borrelia_REV PF03978.13 OEU11279.1 - 0.081 12.9 1.9 0.33 10.9 0.2 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein DUF2227 PF09988.9 OEU11280.1 - 0.062 13.2 0.1 0.077 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Dirigent PF03018.14 OEU11282.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Dirigent-like protein zf-MYND PF01753.18 OEU11285.1 - 3.6e-07 30.2 18.3 9.4e-07 28.8 18.3 1.8 1 0 0 1 1 1 1 MYND finger DUF3449 PF11931.8 OEU11285.1 - 0.11 12.2 2.0 0.22 11.3 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-MYND PF01753.18 OEU11286.1 - 3.5e-05 23.8 17.9 0.00029 20.8 14.2 2.7 1 1 1 2 2 2 2 MYND finger RLL PF10036.9 OEU11286.1 - 0.0037 17.1 0.1 0.004 17.0 0.1 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein DUF4301 PF14134.6 OEU11286.1 - 0.048 12.5 0.1 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) zf-MYND PF01753.18 OEU11290.1 - 1.6e-06 28.1 6.2 1.6e-06 28.1 6.2 1.8 2 0 0 2 2 2 1 MYND finger RVT_1 PF00078.27 OEU11291.1 - 2.2e-05 24.1 0.1 0.00012 21.6 0.1 2.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU11291.1 - 4.7e-05 24.0 1.1 0.00021 22.0 1.1 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HDC PF02329.16 OEU11291.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Histidine carboxylase PI chain Ank_2 PF12796.7 OEU11293.1 - 8.9e-16 58.3 0.0 1.5e-07 31.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU11293.1 - 5.2e-08 32.6 0.1 0.017 15.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OEU11293.1 - 1.2e-07 31.8 0.0 0.00093 19.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU11293.1 - 5.7e-05 23.6 0.0 0.021 15.4 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU11293.1 - 8.1e-05 22.9 0.0 0.53 10.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF4120 PF13496.6 OEU11294.1 - 0.082 13.3 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) Acetyltransf_7 PF13508.7 OEU11295.1 - 2.2e-05 24.8 0.0 3.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU11295.1 - 0.00034 20.6 0.1 0.0047 16.9 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU11295.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 OEU11295.1 - 0.041 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF4367 PF14285.6 OEU11295.1 - 0.049 14.1 0.4 13 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) FR47 PF08445.10 OEU11295.1 - 0.06 13.3 0.2 1.2 9.1 0.2 2.4 1 1 0 1 1 1 0 FR47-like protein CLZ PF16526.5 OEU11296.1 - 0.0085 16.4 0.5 0.024 15.0 0.3 1.8 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 OEU11296.1 - 0.02 13.8 0.8 0.031 13.2 0.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Filo_VP35 PF02097.15 OEU11296.1 - 0.041 12.9 0.2 0.058 12.5 0.2 1.3 1 0 0 1 1 1 0 Filoviridae VP35 COG2 PF06148.11 OEU11296.1 - 0.043 13.9 1.7 3.7 7.6 0.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 OEU11296.1 - 0.06 13.8 2.9 7.5 7.0 0.0 2.7 1 1 3 4 4 4 0 Snapin/Pallidin DUF1664 PF07889.12 OEU11296.1 - 0.089 12.8 2.8 1.4 9.0 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 OEU11296.1 - 0.13 12.5 1.5 0.18 11.9 0.8 1.7 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.12 OEU11296.1 - 1.1 10.0 5.1 2.8 8.6 0.1 3.5 2 1 2 5 5 5 0 SlyX NPV_P10 PF05531.12 OEU11296.1 - 1.1 9.8 11.4 0.16 12.5 1.2 3.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 OEU11296.1 - 1.8 8.8 6.6 4.8 7.4 4.0 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 OEU11296.1 - 9.1 6.5 7.4 1.1 9.5 0.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sulfotransfer_1 PF00685.27 OEU11297.1 - 0.00012 21.6 0.6 0.24 10.9 0.6 3.1 2 1 0 2 2 2 2 Sulfotransferase domain ETRAMP PF09716.10 OEU11297.1 - 0.033 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ank_2 PF12796.7 OEU11298.1 - 0.00014 22.4 0.1 0.036 14.7 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Filo_VP24 PF06389.11 OEU11298.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 RisS_PPD PF16524.5 OEU11298.1 - 0.057 13.7 2.3 0.32 11.3 0.7 2.5 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS CdiI_2 PF18593.1 OEU11301.1 - 1.3 9.8 7.6 1.9 9.2 1.3 2.8 2 0 0 2 2 2 0 CdiI immunity protein DUF5639 PF18690.1 OEU11301.1 - 5.7 7.2 6.6 0.18 12.0 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5639) Yae1_N PF09811.9 OEU11303.1 - 5.6e-15 54.8 60.7 0.05 13.3 0.5 14.4 5 4 6 11 11 11 11 Essential protein Yae1, N terminal MtrG PF04210.13 OEU11303.1 - 0.015 15.1 40.5 2.3 8.1 0.1 10.3 3 3 6 10 10 10 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF697 PF05128.12 OEU11303.1 - 0.026 14.2 21.1 0.95 9.2 0.5 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF697) DUF5308 PF17233.2 OEU11304.1 - 0.016 15.4 4.7 0.025 14.8 4.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RNA_pol_Rpc4 PF05132.14 OEU11304.1 - 0.042 14.3 11.7 0.054 13.9 11.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.12 OEU11304.1 - 0.11 12.8 11.7 0.14 12.4 11.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3807 PF12720.7 OEU11304.1 - 0.11 12.7 12.4 0.13 12.5 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SAPS PF04499.15 OEU11304.1 - 0.14 11.0 4.3 0.14 10.9 4.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 OEU11304.1 - 0.14 10.5 16.5 0.14 10.5 16.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 OEU11304.1 - 0.16 11.7 4.2 0.2 11.4 4.2 1.2 1 0 0 1 1 1 0 Connexin Transformer PF06495.11 OEU11304.1 - 0.23 11.6 8.5 0.27 11.3 8.5 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Striatin PF08232.12 OEU11304.1 - 0.32 11.6 12.0 0.39 11.3 12.0 1.2 1 0 0 1 1 1 0 Striatin family DDHD PF02862.17 OEU11304.1 - 0.38 10.9 6.9 0.5 10.5 6.9 1.3 1 0 0 1 1 1 0 DDHD domain Rtf2 PF04641.12 OEU11304.1 - 0.51 9.7 21.0 0.68 9.2 21.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3464 PF11947.8 OEU11304.1 - 0.63 9.8 21.1 4.9 6.9 21.1 2.0 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 FGF-BP1 PF06473.12 OEU11304.1 - 0.73 9.6 15.4 0.89 9.3 15.4 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Presenilin PF01080.17 OEU11304.1 - 0.8 8.4 9.0 0.92 8.2 9.0 1.1 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 OEU11304.1 - 1.2 9.0 21.0 1.6 8.6 21.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ndc1_Nup PF09531.10 OEU11304.1 - 1.3 7.6 9.2 1.3 7.6 9.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ureide_permease PF07168.11 OEU11304.1 - 1.6 7.4 6.0 2 7.1 6.0 1.1 1 0 0 1 1 1 0 Ureide permease Zip PF02535.22 OEU11304.1 - 1.7 7.8 4.3 1.8 7.7 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 OEU11304.1 - 2 8.5 6.0 2.3 8.3 6.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) OATP PF03137.20 OEU11304.1 - 2 6.6 4.2 2.7 6.2 4.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.16 OEU11304.1 - 2.6 8.0 7.5 2.9 7.9 7.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kei1 PF08552.11 OEU11304.1 - 2.7 7.8 8.6 4.5 7.1 8.6 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NPR3 PF03666.13 OEU11304.1 - 3.1 6.5 14.3 3.5 6.3 14.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Folliculin PF11704.8 OEU11304.1 - 3.1 7.6 8.2 4.5 7.1 8.2 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Atg14 PF10186.9 OEU11304.1 - 3.2 6.8 15.2 3.4 6.7 15.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DAG_kinase_N PF14513.6 OEU11304.1 - 3.8 7.7 11.0 5 7.3 11.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SOBP PF15279.6 OEU11304.1 - 3.8 8.0 12.0 4.8 7.7 12.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein XRN_M PF17846.1 OEU11304.1 - 4.5 6.1 8.5 5.1 5.9 8.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain FlgT_N PF16548.5 OEU11304.1 - 4.6 7.9 6.5 10 6.8 5.0 2.2 1 1 1 2 2 2 0 Flagellar assembly protein T, N-terminal domain TraV PF09676.10 OEU11304.1 - 5.7 7.9 14.4 8.9 7.3 14.4 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) IHABP4_N PF16174.5 OEU11304.1 - 6.9 7.2 19.4 10 6.7 19.4 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal NARP1 PF12569.8 OEU11304.1 - 7.7 5.3 18.6 9.2 5.0 18.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cyclin_N PF00134.23 OEU11305.1 - 1.9e-12 47.1 1.5 2.1e-12 46.9 1.5 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Haemagg_act PF05860.13 OEU11307.1 - 0.1 12.5 0.5 0.18 11.7 0.5 1.4 1 0 0 1 1 1 0 haemagglutination activity domain DNA_pol_phi PF04931.13 OEU11307.1 - 8.6 4.3 15.9 12 3.9 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2101 PF09874.9 OEU11311.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Mpp10 PF04006.12 OEU11311.1 - 0.63 8.4 43.0 0.86 8.0 43.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Utp14 PF04615.13 OEU11311.1 - 6.3 5.2 35.5 0.019 13.6 22.3 2.0 2 0 0 2 2 2 0 Utp14 protein B56 PF01603.20 OEU11312.1 - 2e-170 567.3 0.0 2.3e-170 567.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Na_H_Exchanger PF00999.21 OEU11312.1 - 0.062 12.1 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family DUF1180 PF06679.12 OEU11312.1 - 0.12 12.8 3.5 0.21 12.0 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Redoxin PF08534.10 OEU11315.1 - 1.1e-21 77.1 0.1 1.5e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU11315.1 - 5.6e-06 26.3 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU11316.1 - 5.4e-22 78.1 0.1 7e-22 77.7 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU11316.1 - 3.6e-06 26.9 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA PF00578.21 OEU11317.1 - 1e-24 86.8 0.0 1.6e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU11317.1 - 1e-16 61.0 0.0 2.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OEU11317.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme RPE65 PF03055.15 OEU11318.1 - 5.1e-51 174.3 0.0 6.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 OEU11319.1 - 7.4e-51 173.8 0.0 1e-50 173.3 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CD20 PF04103.15 OEU11319.1 - 0.0022 18.1 0.5 0.0042 17.2 0.5 1.4 1 0 0 1 1 1 1 CD20-like family CA_like PF10563.9 OEU11320.1 - 6.1e-55 185.9 0.1 8.5e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 Putative carbonic anhydrase NAD_binding_1 PF00175.21 OEU11321.1 - 2.8e-20 73.0 0.3 8e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU11321.1 - 0.0038 17.5 0.1 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OEU11321.1 - 0.061 13.4 0.2 0.37 10.9 0.1 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF3494 PF11999.8 OEU11322.1 - 7.5e-50 169.5 15.3 7.5e-50 169.5 15.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU11323.1 - 1.4e-50 171.8 11.9 1.4e-50 171.8 11.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF4138 PF13595.6 OEU11323.1 - 0.12 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF563 PF04577.14 OEU11324.1 - 3.8e-06 27.2 0.0 8.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FA_hydroxylase PF04116.13 OEU11325.1 - 1.5e-19 70.7 12.1 1.5e-19 70.7 12.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA_2 PF07724.14 OEU11328.1 - 4.7e-11 43.1 0.0 1.3e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OEU11328.1 - 3.4e-07 30.8 0.0 6.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OEU11328.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OEU11328.1 - 1.1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU11328.1 - 1.8e-05 25.0 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OEU11328.1 - 0.0001 21.8 0.1 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OEU11328.1 - 0.00044 20.7 0.0 0.0073 16.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OEU11328.1 - 0.0039 17.1 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CbiA PF01656.23 OEU11328.1 - 0.027 14.5 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Torsin PF06309.11 OEU11328.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_24 PF13479.6 OEU11328.1 - 0.04 13.6 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 OEU11328.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 OEU11328.1 - 0.098 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CRA PF06589.11 OEU11329.1 - 0.011 15.9 1.7 0.011 15.9 1.7 2.4 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Fasciclin PF02469.22 OEU11331.1 - 4.6e-14 52.7 0.0 8.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain SET PF00856.28 OEU11332.1 - 0.0036 17.7 0.9 0.09 13.2 0.9 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 OEU11332.1 - 0.11 13.2 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 SAF domain DUF3388 PF11868.8 OEU11334.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) FAD_binding_3 PF01494.19 OEU11336.1 - 2.5e-14 53.3 0.0 3.3e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 OEU11336.1 - 0.084 11.9 0.0 0.81 8.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.19 OEU11337.1 - 2.6e-17 63.1 0.2 1.3e-06 27.9 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 OEU11337.1 - 2.8e-05 24.3 0.2 8e-05 22.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU11337.1 - 3.6e-05 23.1 0.0 6.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU11337.1 - 0.00014 22.3 0.0 0.0003 21.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU11337.1 - 0.00063 19.4 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OEU11337.1 - 0.00067 18.8 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OEU11337.1 - 0.00071 18.4 0.1 0.0012 17.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 OEU11337.1 - 0.00082 18.5 0.0 0.0038 16.3 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 OEU11337.1 - 0.0023 17.1 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OEU11337.1 - 0.0045 16.3 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Glu_dehyd_C PF16912.5 OEU11337.1 - 0.023 14.2 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 OEU11337.1 - 0.055 12.7 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OEU11337.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OEU11337.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 OEU11337.1 - 0.071 12.4 0.5 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short_C2 PF13561.6 OEU11338.1 - 1.7e-28 99.7 0.2 2.9e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU11338.1 - 2.3e-12 46.8 0.1 3.9e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Integrase_H2C2 PF17921.1 OEU11338.1 - 9.5e-06 25.6 2.8 1.6e-05 24.9 2.8 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Epimerase PF01370.21 OEU11338.1 - 0.00011 21.7 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OEU11338.1 - 0.00018 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OEU11338.1 - 0.14 11.5 0.0 0.71 9.2 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PHM7_cyt PF14703.6 OEU11338.1 - 0.22 11.7 0.3 0.35 11.1 0.3 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter HA PF03457.14 OEU11339.1 - 2.3e-50 168.8 11.0 3.1e-17 62.6 0.9 3.0 3 0 0 3 3 3 3 Helicase associated domain Methyltransf_22 PF13383.6 OEU11339.1 - 0.54 9.8 6.8 4.4 6.8 0.2 3.1 2 1 1 3 3 3 0 Methyltransferase domain zf-C3HC4_3 PF13920.6 OEU11340.1 - 1.6e-07 31.1 6.3 1.6e-07 31.1 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU11340.1 - 5.6e-05 22.9 8.0 5.6e-05 22.9 8.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 NTF2 PF02136.20 OEU11340.1 - 0.0061 17.1 0.3 1.1 9.9 0.1 2.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Ax_dynein_light PF10211.9 OEU11341.1 - 0.53 10.2 11.0 1.1 9.2 11.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain SPT16 PF08644.11 OEU11341.1 - 2.4 8.3 5.8 4.5 7.5 5.8 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Menin PF05053.13 OEU11343.1 - 6.2 5.0 17.9 2.7 6.2 4.8 2.2 2 0 0 2 2 2 0 Menin GREB1 PF15782.5 OEU11343.1 - 7.5 3.5 14.2 11 3.0 14.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BUD22 PF09073.10 OEU11343.1 - 8.2 5.6 32.3 0.55 9.5 14.6 2.4 1 1 0 2 2 2 0 BUD22 Dirigent PF03018.14 OEU11347.1 - 0.015 15.1 0.2 0.035 13.9 0.2 1.6 1 0 0 1 1 1 0 Dirigent-like protein PqqD PF05402.12 OEU11348.1 - 0.13 12.6 0.4 0.49 10.7 0.2 2.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) P2X_receptor PF00864.19 OEU11349.1 - 8.3e-23 81.0 7.0 1.9e-21 76.6 7.0 2.5 1 1 0 1 1 1 1 ATP P2X receptor DUF3641 PF12345.8 OEU11349.1 - 0.0024 17.9 0.9 0.0024 17.9 0.9 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3641) zf-MYND PF01753.18 OEU11350.1 - 2.3e-07 30.8 18.9 4.1e-07 30.0 18.9 1.4 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 OEU11352.1 - 9.6e-16 58.2 0.0 1.8e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU11352.1 - 5.5e-12 44.8 0.1 0.037 14.6 0.0 4.1 3 1 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OEU11352.1 - 6.6e-10 39.0 0.0 0.055 13.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OEU11352.1 - 3e-06 27.7 0.1 0.066 13.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU11352.1 - 0.0019 18.5 0.3 6.1 7.3 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) zf-SNAP50_C PF12251.8 OEU11352.1 - 0.008 15.9 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_4 PF13894.6 OEU11353.1 - 0.024 15.5 3.0 6.7 7.8 1.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OEU11353.1 - 0.059 13.5 1.4 0.16 12.1 1.3 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger ThrE PF06738.12 OEU11353.1 - 0.073 12.4 0.1 0.097 12.0 0.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter zf-C2H2 PF00096.26 OEU11353.1 - 0.13 12.7 4.4 12 6.6 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type LRR_4 PF12799.7 OEU11356.1 - 0.0019 18.6 8.1 2.1 8.9 0.5 3.9 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) CTP_transf_like PF01467.26 OEU11357.1 - 0.045 13.9 4.1 2.3 8.4 0.2 2.3 2 0 0 2 2 2 0 Cytidylyltransferase-like Utp14 PF04615.13 OEU11357.1 - 0.27 9.8 32.6 0.31 9.6 32.6 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.6 OEU11357.1 - 0.6 10.7 12.8 0.93 10.0 12.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Pannexin_like PF12534.8 OEU11357.1 - 1.1 8.3 13.4 3.1 6.8 13.4 1.8 1 1 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF3446 PF11928.8 OEU11357.1 - 2.6 8.4 11.8 19 5.6 7.9 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Macoilin PF09726.9 OEU11358.1 - 0.25 9.9 1.2 0.25 9.9 1.2 1.0 1 0 0 1 1 1 0 Macoilin family HA PF03457.14 OEU11360.1 - 7.7e-29 99.8 3.4 6.3e-15 55.3 0.2 2.1 2 0 0 2 2 2 2 Helicase associated domain PH PF00169.29 OEU11361.1 - 0.0075 16.8 0.0 0.035 14.6 0.0 2.2 1 0 0 1 1 1 1 PH domain Mucin PF01456.17 OEU11361.1 - 0.86 9.6 26.1 0.29 11.1 0.6 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein RSN1_TM PF13967.6 OEU11362.1 - 1.3e-05 25.0 0.2 3.4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Phage_GPL PF05926.11 OEU11363.1 - 0.093 12.7 2.6 1.6 8.7 1.0 2.6 2 0 0 2 2 2 0 Phage head completion protein (GPL) OxoDH_E1alpha_N PF12573.8 OEU11363.1 - 0.11 12.3 0.2 0.26 11.1 0.2 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF1539 PF07560.11 OEU11364.1 - 0.073 13.2 0.0 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) BTB_2 PF02214.22 OEU11365.1 - 9.8e-07 29.1 0.0 4.5e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain SlyX PF04102.12 OEU11366.1 - 0.0016 19.0 1.5 0.0016 19.0 1.5 2.5 2 0 0 2 2 2 1 SlyX Leu_Phe_trans PF03588.14 OEU11367.1 - 0.094 12.2 0.2 0.26 10.8 0.2 1.7 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase cobW PF02492.19 OEU11368.1 - 1.3e-33 116.0 3.0 2.2e-33 115.3 3.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU11368.1 - 1.6e-05 24.7 0.0 0.0038 17.1 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 OEU11368.1 - 0.041 14.4 0.8 0.088 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 OEU11368.1 - 0.044 13.7 0.8 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 OEU11368.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 OEU11368.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 OEU11368.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TMEM154 PF15102.6 OEU11369.1 - 0.00057 19.8 2.2 0.00057 19.8 2.2 1.7 2 1 0 2 2 2 1 TMEM154 protein family SARAF PF06682.12 OEU11369.1 - 0.0044 16.7 0.4 0.0063 16.2 0.4 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BatD PF13584.6 OEU11369.1 - 0.019 13.8 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance TMEM51 PF15345.6 OEU11369.1 - 0.028 14.3 0.4 0.037 13.9 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Stevor PF17410.2 OEU11369.1 - 0.033 13.7 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1634 PF07843.11 OEU11369.1 - 0.038 14.1 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) PalH PF08733.10 OEU11369.1 - 0.043 12.8 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 PalH/RIM21 DUF4834 PF16118.5 OEU11369.1 - 0.045 14.7 8.8 0.26 12.3 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF1218 PF06749.12 OEU11369.1 - 0.045 14.3 0.1 0.068 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) EphA2_TM PF14575.6 OEU11369.1 - 0.059 14.2 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OEU11369.1 - 0.074 12.9 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Rifin SID-1_RNA_chan PF13965.6 OEU11369.1 - 0.1 11.0 0.2 0.11 10.9 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF5383 PF17355.2 OEU11369.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.0 2 1 1 3 3 3 0 Family of unknown function (DUF5383) SSP160 PF06933.11 OEU11369.1 - 0.91 7.6 13.7 1.1 7.3 13.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAM176 PF14851.6 OEU11369.1 - 4.4 7.0 6.4 0.77 9.4 0.1 2.4 1 1 2 3 3 3 0 FAM176 family FA_hydroxylase PF04116.13 OEU11370.1 - 2.2e-12 47.4 16.6 2.2e-12 47.4 16.6 2.7 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily ABC2_membrane_3 PF12698.7 OEU11373.1 - 2.6 7.1 3.6 3 6.9 3.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Coilin_N PF15862.5 OEU11374.1 - 0.0049 16.7 2.1 0.0049 16.7 2.1 2.8 3 0 0 3 3 3 1 Coilin N-terminus RPA43_OB PF17875.1 OEU11374.1 - 0.03 14.9 3.2 0.03 14.9 3.2 2.9 2 1 0 2 2 2 0 RPA43 OB domain in RNA Pol I CSG2 PF16965.5 OEU11374.1 - 0.049 12.6 1.5 0.54 9.1 0.8 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator DUF5308 PF17233.2 OEU11374.1 - 0.052 13.8 6.3 0.081 13.2 2.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Spt20 PF12090.8 OEU11374.1 - 0.054 13.1 18.8 0.17 11.5 11.2 2.3 2 0 0 2 2 2 0 Spt20 family Myc_N PF01056.18 OEU11374.1 - 0.079 12.8 12.9 0.033 14.1 5.4 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Serinc PF03348.15 OEU11374.1 - 0.15 10.9 2.0 0.3 9.9 0.6 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) MID_MedPIWI PF18296.1 OEU11374.1 - 1.8 8.3 13.9 1.2 8.8 9.2 2.2 2 0 0 2 2 2 0 MID domain of medPIWI EOS1 PF12326.8 OEU11374.1 - 5.5 6.9 7.8 3.3 7.6 4.8 1.9 2 0 0 2 2 2 0 N-glycosylation protein Presenilin PF01080.17 OEU11374.1 - 6.2 5.5 17.9 0.32 9.7 5.8 2.1 2 0 0 2 2 2 0 Presenilin DUF4834 PF16118.5 OEU11374.1 - 8.7 7.4 21.0 0.56 11.2 9.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3494 PF11999.8 OEU11378.1 - 1.8e-39 135.5 6.5 2e-39 135.4 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Arrestin_N PF00339.29 OEU11380.1 - 1.7e-08 34.6 0.0 3.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OEU11380.1 - 0.013 15.9 0.0 0.26 11.7 0.0 2.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF4476 PF14771.6 OEU11380.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) SOP4 PF17081.5 OEU11380.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein SUIM_assoc PF16619.5 OEU11381.1 - 0.0044 17.0 0.5 0.0044 17.0 0.5 1.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF1189 PF06691.11 OEU11381.1 - 0.69 9.4 4.8 0.92 9.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) RXT2_N PF08595.11 OEU11382.1 - 0.15 12.1 12.0 0.63 10.1 8.5 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Drf_GBD PF06371.13 OEU11382.1 - 0.42 10.1 4.4 0.19 11.3 0.3 2.5 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain DUF4611 PF15387.6 OEU11382.1 - 0.99 9.7 13.9 4.9 7.4 8.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Med13_C PF06333.12 OEU11382.1 - 1.8 7.8 10.6 3.8 6.7 9.7 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain WD40 PF00400.32 OEU11383.1 - 1.8e-06 28.5 4.6 1.1e-05 26.0 0.3 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 OEU11383.1 - 5.8e-05 22.9 0.4 0.11 12.4 0.0 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 OEU11383.1 - 0.052 11.6 0.3 0.28 9.1 0.1 1.8 2 0 0 2 2 2 0 IKI3 family HA PF03457.14 OEU11384.1 - 4.8e-39 132.5 5.7 3.6e-17 62.4 0.7 3.1 3 0 0 3 3 3 3 Helicase associated domain DUF3836 PF12930.7 OEU11384.1 - 0.19 11.5 6.0 2.3 8.0 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF3836) DNA_pol_A_exo1 PF01612.20 OEU11385.1 - 1.9e-13 50.5 0.2 6.1e-13 48.9 0.2 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Hs1pro-1_C PF07014.12 OEU11385.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Dirigent PF03018.14 OEU11388.1 - 0.023 14.5 0.3 0.055 13.3 0.3 1.6 1 0 0 1 1 1 0 Dirigent-like protein Polysacc_deac_1 PF01522.21 OEU11389.1 - 4.4e-14 52.4 0.3 9.5e-14 51.4 0.3 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase BUD22 PF09073.10 OEU11389.1 - 0.0031 16.9 26.1 0.02 14.2 1.0 2.6 2 1 0 2 2 2 2 BUD22 GRP PF07172.11 OEU11389.1 - 0.2 12.4 4.0 0.52 11.0 1.8 2.7 2 0 0 2 2 2 0 Glycine rich protein family LPD7 PF18821.1 OEU11393.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 DUF5312 PF17239.2 OEU11399.1 - 0.13 10.6 1.1 0.21 9.9 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5312) YopE_N PF09020.10 OEU11400.1 - 0.45 10.8 3.6 0.38 11.0 1.6 1.8 1 1 1 2 2 2 0 YopE, N terminal MatE PF01554.18 OEU11400.1 - 2.1 8.0 6.4 3.1 7.4 2.5 2.0 1 1 0 2 2 2 0 MatE PT PF04886.12 OEU11401.1 - 0.11 12.0 18.9 0.2 11.2 18.9 1.4 1 0 0 1 1 1 0 PT repeat ANTH PF07651.16 OEU11402.1 - 0.0056 15.7 1.1 0.0056 15.7 1.1 1.8 1 1 0 1 1 1 1 ANTH domain EMC3_TMCO1 PF01956.16 OEU11404.1 - 0.044 13.5 0.0 0.25 11.1 0.0 2.2 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF1579 PF07617.11 OEU11404.1 - 0.18 11.8 0.7 0.4 10.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) RNA_pol_Rpc4 PF05132.14 OEU11404.1 - 0.2 12.1 5.2 0.35 11.3 2.3 2.7 3 0 0 3 3 3 0 RNA polymerase III RPC4 DUF3987 PF13148.6 OEU11404.1 - 1.1 8.2 4.6 1.9 7.4 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CPSF100_C PF13299.6 OEU11404.1 - 5.6 7.1 9.1 1.6 8.9 1.7 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Mito_fiss_reg PF05308.11 OEU11405.1 - 0.045 13.8 10.4 0.095 12.8 10.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator SOG2 PF10428.9 OEU11405.1 - 6.7 5.8 22.3 14 4.7 22.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM171 PF15471.6 OEU11405.1 - 7.6 5.4 8.0 11 4.9 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF951 PF06107.11 OEU11406.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) LAX PF15681.5 OEU11406.1 - 0.088 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X SUIM_assoc PF16619.5 OEU11407.1 - 0.54 10.4 15.4 0.063 13.4 2.6 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Neur_chan_memb PF02932.16 OEU11407.1 - 7.9 6.5 9.7 0.58 10.2 2.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TPR_MLP1_2 PF07926.12 OEU11408.1 - 0.17 12.0 0.1 0.17 12.0 0.1 8.5 5 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 OEU11408.1 - 0.31 11.7 0.0 0.31 11.7 0.0 7.7 5 2 3 8 8 8 0 Initiation control protein YabA DUF4710 PF15828.5 OEU11408.1 - 5.1 7.3 12.2 0.26 11.5 3.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF4140 PF13600.6 OEU11408.1 - 7.5 7.1 34.2 0.15 12.5 4.9 6.8 6 2 0 6 6 6 0 N-terminal domain of unknown function (DUF4140) LRR_8 PF13855.6 OEU11409.1 - 9.3e-19 67.0 27.4 5.9e-08 32.4 3.5 4.6 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OEU11409.1 - 2e-18 66.2 31.9 0.00033 21.0 8.5 6.1 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11409.1 - 1.9e-07 30.7 22.9 11 7.1 0.0 10.0 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_2 PF07723.13 OEU11409.1 - 0.0028 18.3 0.7 24 5.8 0.0 5.1 4 0 0 4 4 4 1 Leucine Rich Repeat Chorion_2 PF03964.15 OEU11413.1 - 7.8 7.4 16.2 0.37 11.7 5.7 2.7 2 1 0 2 2 2 0 Chorion family 2 Clr2 PF10383.9 OEU11415.1 - 0.055 14.3 1.1 0.1 13.4 1.1 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DZR PF12773.7 OEU11415.1 - 0.13 12.3 1.8 0.29 11.2 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU11415.1 - 0.13 12.0 0.7 0.28 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain PFEMP PF03011.15 OEU11415.1 - 0.24 12.0 4.9 0.074 13.7 1.2 2.1 2 0 0 2 2 2 0 PFEMP DBL domain Ribosomal_S2 PF00318.20 OEU11415.1 - 2.2 7.5 6.5 0.13 11.5 0.5 2.1 3 0 0 3 3 3 0 Ribosomal protein S2 Yae1_N PF09811.9 OEU11417.1 - 1.2e-08 34.5 58.8 0.025 14.2 0.5 14.8 7 4 5 12 12 12 8 Essential protein Yae1, N terminal MspA PF09203.11 OEU11417.1 - 0.35 10.7 9.2 9.2 6.1 4.2 4.1 1 1 1 2 2 2 0 MspA UPF0176_N PF17773.1 OEU11419.1 - 2.6e-10 40.5 0.0 1.1e-09 38.5 0.0 2.1 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 OEU11419.1 - 4.9e-08 33.2 2.9 4.9e-08 33.2 2.9 2.9 3 0 0 3 3 3 1 Rhodanase C-terminal PseudoU_synth_2 PF00849.22 OEU11419.1 - 7.3e-07 29.4 5.6 7.6e-07 29.4 0.0 3.3 4 0 0 4 4 4 1 RNA pseudouridylate synthase zf-HC3 PF16827.5 OEU11419.1 - 0.0031 17.7 4.4 0.0071 16.5 0.4 2.7 2 0 0 2 2 2 1 zinc-finger DUF3039 PF11238.8 OEU11419.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Lamprin PF06403.11 OEU11419.1 - 0.081 12.9 3.6 0.18 11.8 3.6 1.5 1 0 0 1 1 1 0 Lamprin Porin_10 PF14121.6 OEU11420.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative porin DDE_Tnp_1 PF01609.21 OEU11422.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain R2K_3 PF14243.6 OEU11423.1 - 0.0088 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 PT PF04886.12 OEU11424.1 - 1.6e-21 75.5 132.4 1.6 8.3 1.9 9.5 1 1 3 4 4 4 1 PT repeat DUF285 PF03382.14 OEU11425.1 - 7.9e-61 203.2 26.4 3.5e-32 110.7 11.5 2.2 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Lin-8 PF03353.15 OEU11431.1 - 4.4 6.8 17.2 0.046 13.3 4.1 2.0 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1635 PF07795.11 OEU11431.1 - 5 6.9 12.3 2.9 7.7 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Aldo_ket_red PF00248.21 OEU11432.1 - 7.8e-13 48.3 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family FSA_C PF10479.9 OEU11432.1 - 0.11 10.6 15.4 0.16 10.1 15.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Gly_transf_sug PF04488.15 OEU11434.1 - 0.0031 18.1 1.5 0.0042 17.7 0.1 1.9 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif HofP PF10748.9 OEU11435.1 - 0.088 12.4 1.2 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 DNA utilization proteins HofP DUF3452 PF11934.8 OEU11435.1 - 0.14 11.7 3.7 0.23 11.0 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Polo_box_3 PF18544.1 OEU11435.1 - 0.15 12.8 1.7 5 7.8 1.7 2.2 1 1 1 2 2 2 0 Polo box domain VP4_helical PF17478.2 OEU11435.1 - 0.21 11.0 5.7 0.26 10.7 5.7 1.2 1 0 0 1 1 1 0 Rotavirus VP4 helical domain Ly49 PF08391.10 OEU11435.1 - 0.93 9.9 5.2 1.4 9.3 5.2 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Exonuc_VII_L PF02601.15 OEU11435.1 - 3.5 7.1 8.4 3.8 7.0 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 OEU11437.1 - 0.01 16.4 1.0 0.01 16.4 1.0 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cep57_CLD_2 PF14197.6 OEU11437.1 - 0.71 10.0 6.7 0.083 13.0 1.7 2.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 CP12 PF02672.15 OEU11438.1 - 4.5e-07 30.5 1.4 0.013 16.2 0.1 2.7 2 1 0 2 2 2 2 CP12 domain HemY_N PF07219.13 OEU11438.1 - 0.036 14.3 0.6 0.092 13.0 0.2 1.8 2 0 0 2 2 2 0 HemY protein N-terminus IMUP PF15761.5 OEU11438.1 - 9.2 7.0 9.2 19 6.0 9.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3494 PF11999.8 OEU11441.1 - 5.4e-31 107.9 13.6 1e-30 107.0 13.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) Yae1_N PF09811.9 OEU11443.1 - 0.00094 18.8 20.2 5.9 6.7 1.6 6.9 1 1 2 3 3 3 1 Essential protein Yae1, N terminal MtrG PF04210.13 OEU11443.1 - 0.082 12.8 5.5 17 5.3 1.5 4.2 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Gly-zipper_OmpA PF13436.6 OEU11443.1 - 0.17 11.7 16.6 16 5.3 0.9 4.0 1 1 1 2 2 2 0 Glycine-zipper domain MspA PF09203.11 OEU11443.1 - 0.21 11.4 3.8 7.5 6.4 3.8 2.2 1 1 0 1 1 1 0 MspA Na_Pi_cotrans PF02690.15 OEU11443.1 - 0.51 10.4 2.9 28 4.8 0.0 3.2 3 0 0 3 3 3 0 Na+/Pi-cotransporter Rick_17kDa_Anti PF05433.15 OEU11443.1 - 3.3 7.6 20.1 0.79 9.6 0.8 3.9 1 1 2 3 3 3 0 Glycine zipper 2TM domain Keratin_2_head PF16208.5 OEU11443.1 - 8.2 6.5 13.0 17 5.5 1.3 2.7 1 1 1 2 2 2 0 Keratin type II head DDE_Tnp_1_7 PF13843.6 OEU11447.1 - 6.4e-18 65.2 0.1 1.3e-17 64.2 0.1 1.5 1 1 0 1 1 1 1 Transposase IS4 zf-RVT PF13966.6 OEU11448.1 - 0.01 16.5 2.9 0.011 16.4 0.9 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Mei5_like PF17021.5 OEU11448.1 - 0.092 12.8 0.1 0.092 12.8 0.1 3.4 2 1 1 3 3 3 0 Putative double-strand recombination repair-like Imm5 PF14423.6 OEU11449.1 - 0.00072 19.8 1.1 0.00072 19.8 1.1 3.4 3 2 1 4 4 4 1 Immunity protein Imm5 DMAP_binding PF06464.11 OEU11450.1 - 0.091 13.6 1.2 0.84 10.5 0.1 2.7 3 0 0 3 3 3 0 DMAP1-binding Domain DUF2207 PF09972.9 OEU11450.1 - 0.35 9.6 4.1 0.11 11.3 1.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CS PF04969.16 OEU11452.1 - 5.8e-07 30.4 3.7 2.5e-06 28.4 3.7 2.1 1 1 0 1 1 1 1 CS domain PepSY PF03413.19 OEU11454.1 - 0.13 12.8 0.1 0.14 12.7 0.1 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain MIF PF01187.18 OEU11455.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) E1_dh PF00676.20 OEU11456.1 - 3.3e-53 180.6 0.0 6.1e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 OEU11456.1 - 2.6e-27 95.2 0.7 1e-25 90.0 0.1 2.8 3 0 0 3 3 3 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 OEU11456.1 - 7.1e-14 51.9 0.0 1.7e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 OEU11456.1 - 0.07 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II UPF0016 PF01169.19 OEU11457.1 - 4.2e-37 126.3 25.5 7.2e-19 67.9 9.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 zf-CCHC PF00098.23 OEU11461.1 - 0.0014 18.6 4.7 0.0038 17.2 4.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OEU11461.1 - 0.0031 17.4 2.6 0.0088 16.0 2.6 1.8 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 OEU11461.1 - 6 5.0 10.0 13 3.9 10.0 1.5 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_4 PF01565.23 OEU11462.1 - 1.8e-11 44.0 2.3 2.1e-10 40.5 2.3 2.4 1 1 0 1 1 1 1 FAD binding domain CPW_WPC PF09717.10 OEU11462.1 - 5.2e-05 24.1 1.4 0.12 13.3 0.3 2.8 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) BBE PF08031.12 OEU11462.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Alba PF01918.21 OEU11465.1 - 1.3e-19 69.7 0.1 2.3e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 OEU11465.1 - 1.1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P DUF2815 PF10991.8 OEU11465.1 - 0.2 11.6 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Ank_2 PF12796.7 OEU11466.1 - 9.4e-09 35.7 0.7 9e-06 26.2 0.7 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU11466.1 - 2.8e-08 33.4 0.4 0.072 13.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OEU11466.1 - 8e-06 26.0 0.4 0.0064 16.8 0.3 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU11466.1 - 2.2e-05 24.7 0.3 0.69 10.5 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OEU11466.1 - 0.0012 19.4 0.1 0.37 11.4 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) CBFB_NFYA PF02045.15 OEU11468.1 - 1.7e-23 82.9 8.2 1.7e-23 82.9 8.2 5.0 4 1 0 4 4 4 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Alpha_GJ PF03229.13 OEU11468.1 - 2.6 8.6 17.0 2.6 8.6 1.4 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J Ctr PF04145.15 OEU11470.1 - 1.5e-07 32.2 8.8 1.5e-07 32.2 8.8 2.0 2 0 0 2 2 2 1 Ctr copper transporter family PRIMA1 PF16101.5 OEU11472.1 - 0.058 13.4 4.5 0.12 12.4 4.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EPF PF17181.4 OEU11472.1 - 7.1 6.7 6.1 4.5e+02 1.0 6.1 2.7 1 1 0 1 1 1 0 Epidermal patterning factor proteins TPR_12 PF13424.6 OEU11473.1 - 9.1e-26 90.0 5.6 2.1e-13 50.3 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU11473.1 - 2.7e-10 39.8 0.2 7.6e-07 28.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11473.1 - 2.1e-06 27.3 0.3 0.55 10.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU11473.1 - 2.3e-06 27.2 0.6 0.071 13.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU11473.1 - 0.00023 21.1 2.1 0.011 15.9 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU11473.1 - 0.0022 18.2 0.4 2.9 8.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3682 PF12446.8 OEU11473.1 - 0.0073 16.8 13.8 0.0073 16.8 13.8 5.2 4 1 3 7 7 4 1 Protein of unknown function (DUF3682) TPR_11 PF13414.6 OEU11473.1 - 0.051 13.3 0.2 1.7 8.4 0.1 2.8 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 OEU11473.1 - 0.081 13.0 0.2 3.8 7.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU11473.1 - 0.082 13.6 0.1 16 6.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU11473.1 - 0.17 12.8 1.6 1.7 9.7 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 OEU11473.1 - 1.3 7.3 4.9 2.9 6.2 4.9 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SET PF00856.28 OEU11474.1 - 4.8e-06 27.1 1.0 0.00056 20.3 0.0 3.3 2 2 0 2 2 2 1 SET domain ODV-E18 PF10717.9 OEU11474.1 - 0.00074 19.3 1.1 0.0027 17.5 1.1 1.9 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 SUIM_assoc PF16619.5 OEU11474.1 - 0.11 12.5 10.0 0.28 11.3 10.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 OEU11474.1 - 0.25 12.3 8.9 1 10.3 2.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 OEU11474.1 - 0.6 11.0 5.3 6.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Conotoxin PF02950.17 OEU11474.1 - 1.2 10.2 0.0 1.2 10.2 0.0 3.4 4 0 0 4 4 4 0 Conotoxin DUF4711 PF15829.5 OEU11474.1 - 8.3 6.3 6.9 0.48 10.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) Yae1_N PF09811.9 OEU11475.1 - 5.4e-07 29.2 65.5 4.1 7.2 0.6 16.5 3 2 9 12 12 12 6 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU11475.1 - 0.065 13.2 75.4 0.06 13.4 8.1 8.8 2 2 5 7 7 7 0 Glycine zipper DUF826 PF05696.11 OEU11475.1 - 0.23 11.6 3.9 39 4.4 0.1 4.4 3 2 3 6 6 6 0 Protein of unknown function (DUF826) Rick_17kDa_Anti PF05433.15 OEU11475.1 - 1.5 8.7 90.2 0.099 12.5 10.0 10.2 2 2 7 9 9 9 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 OEU11475.1 - 6.9 6.5 79.1 0.4 10.5 4.7 9.5 4 3 3 7 7 7 0 Glycine-zipper domain Serglycin PF04360.12 OEU11476.1 - 0.00029 20.8 6.7 0.00033 20.6 6.2 1.4 1 1 0 1 1 1 1 Serglycin AF-4 PF05110.13 OEU11476.1 - 0.091 10.8 0.0 0.1 10.7 0.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DDE_Tnp_1_7 PF13843.6 OEU11478.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Transposase IS4 DUF4604 PF15377.6 OEU11479.1 - 0.011 16.1 3.3 0.011 16.1 3.3 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) XRCC4 PF06632.12 OEU11479.1 - 0.36 9.6 10.7 0.02 13.8 2.6 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PCSK9_C1 PF18459.1 OEU11479.1 - 0.74 10.0 3.7 0.52 10.5 1.3 2.0 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PBP1_TM PF14812.6 OEU11479.1 - 5.9 7.3 6.5 0.53 10.7 1.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phage_holin_3_3 PF16083.5 OEU11480.1 - 0.00047 20.2 1.4 1.4 9.1 0.1 3.3 3 1 0 3 3 3 2 LydA holin phage, holin superfamily III ubiquitin PF00240.23 OEU11482.1 - 0.043 13.6 0.5 0.19 11.5 0.5 1.9 1 1 0 1 1 1 0 Ubiquitin family COX16 PF14138.6 OEU11482.1 - 0.15 12.6 1.6 0.47 11.0 1.2 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 CopK PF11525.8 OEU11483.1 - 0.025 14.2 1.3 1.7 8.3 0.1 2.4 1 1 1 2 2 2 0 Copper resistance protein K FGAR-AT_linker PF18072.1 OEU11483.1 - 0.075 13.6 0.8 0.52 10.9 0.1 2.5 1 1 1 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain PKcGMP_CC PF16808.5 OEU11483.1 - 0.14 12.1 3.4 7.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0014 PF03649.13 OEU11484.1 - 6.1e-68 228.8 18.9 7.1e-68 228.6 18.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) RB_A PF01858.17 OEU11484.1 - 0.23 11.2 0.4 0.47 10.3 0.4 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain MRAP PF15183.6 OEU11484.1 - 3.4 7.7 5.6 0.78 9.7 0.1 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Mucin PF01456.17 OEU11487.1 - 0.0045 17.0 6.8 0.0061 16.5 6.8 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein HAD_2 PF13419.6 OEU11487.1 - 0.23 11.5 3.2 0.35 10.9 2.9 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FKS1_dom1 PF14288.6 OEU11487.1 - 1.4 9.2 4.2 2.8 8.3 2.8 1.9 1 1 1 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 S_2TMBeta PF18153.1 OEU11487.1 - 3.9 7.2 10.2 0.35 10.6 4.7 1.7 1 1 1 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain DUF285 PF03382.14 OEU11488.1 - 3.5e-103 339.9 69.2 3.2e-38 130.2 14.4 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 ATG11 PF10377.9 OEU11488.1 - 0.07 13.2 2.4 9.6 6.3 0.3 2.7 1 1 1 2 2 2 0 Autophagy-related protein 11 DUF1965 PF09248.10 OEU11488.1 - 0.082 12.7 10.9 1.5 8.7 0.0 4.5 1 1 5 6 6 6 0 Domain of unknown function (DUF1965) Neugrin PF06413.11 OEU11489.1 - 2.9 7.8 6.4 3.5 7.6 6.4 1.1 1 0 0 1 1 1 0 Neugrin SPX PF03105.19 OEU11489.1 - 8.6 6.2 16.7 11 5.9 16.7 1.1 1 0 0 1 1 1 0 SPX domain PI3K_1B_p101 PF10486.9 OEU11489.1 - 9.1 3.9 10.1 9.2 3.9 10.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3339 PF11820.8 OEU11490.1 - 0.09 13.0 5.4 0.2 11.9 5.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3339) DUF3671 PF12420.8 OEU11490.1 - 0.9 9.6 7.0 0.99 9.5 6.6 1.3 1 1 0 1 1 1 0 Protein of unknown function Shisa PF13908.6 OEU11490.1 - 1.5 9.1 6.1 1.8 8.8 6.1 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CAAD PF14159.6 OEU11490.1 - 2.2 8.2 7.1 0.22 11.3 2.8 1.5 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DDE_Tnp_1 PF01609.21 OEU11492.1 - 0.0002 21.1 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain rve PF00665.26 OEU11492.1 - 0.035 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 OEU11495.1 - 7e-05 22.4 0.0 0.00029 20.4 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU11495.1 - 0.011 16.5 0.5 0.044 14.5 0.5 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase 4_1_CTD PF05902.13 OEU11495.1 - 0.087 12.9 6.5 0.31 11.1 6.5 2.0 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) cPLA2_C2 PF18695.1 OEU11496.1 - 0.0094 15.9 0.1 0.033 14.2 0.1 1.9 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain Alpha_kinase PF02816.18 OEU11500.1 - 5.3e-23 82.1 0.2 5e-16 59.3 0.3 2.3 1 1 1 2 2 2 2 Alpha-kinase family Stc1 PF12898.7 OEU11500.1 - 0.00043 20.8 3.9 0.001 19.6 3.9 1.7 1 0 0 1 1 1 1 Stc1 domain zf-trcl PF13451.6 OEU11501.1 - 4.3e-19 68.1 3.3 4.3e-19 68.1 3.3 2.1 2 0 0 2 2 2 1 Probable zinc-ribbon domain zf-CCHC PF00098.23 OEU11501.1 - 3.2e-08 33.3 3.2 3.2e-08 33.3 3.2 2.0 2 0 0 2 2 2 1 Zinc knuckle FlhC PF05280.11 OEU11501.1 - 0.14 11.9 0.7 0.21 11.3 0.7 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) SR-25 PF10500.9 OEU11501.1 - 0.91 9.1 7.8 1.5 8.4 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 OEU11501.1 - 1 7.4 6.4 1.3 7.1 6.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein API5 PF05918.11 OEU11501.1 - 7 5.3 8.7 11 4.7 8.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SET PF00856.28 OEU11502.1 - 2e-17 64.1 0.0 2e-14 54.4 0.0 2.2 1 1 1 2 2 2 2 SET domain SAF PF08666.12 OEU11502.1 - 0.0044 17.6 0.0 0.24 12.0 0.0 2.2 2 0 0 2 2 2 1 SAF domain AWS PF17907.1 OEU11502.1 - 0.017 15.1 3.8 0.017 15.1 3.8 3.1 3 0 0 3 3 3 0 AWS domain SET PF00856.28 OEU11503.1 - 6.1e-06 26.7 1.1 6.1e-06 26.7 1.1 2.7 2 1 0 2 2 2 1 SET domain tRNA_U5-meth_tr PF05958.11 OEU11504.1 - 5e-18 65.2 0.0 1.1e-17 64.1 0.0 1.5 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OEU11504.1 - 6.7e-06 26.0 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU11504.1 - 8.1e-05 23.2 0.0 0.00021 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU11504.1 - 0.0002 20.8 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OEU11504.1 - 0.0066 17.1 0.1 0.039 14.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU11504.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OEU11504.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 OEU11504.1 - 0.023 14.3 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 OEU11504.1 - 0.04 13.5 0.1 0.079 12.5 0.1 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 OEU11504.1 - 0.063 12.9 0.2 0.14 11.7 0.2 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 OEU11504.1 - 0.097 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA methylase DnaJ PF00226.31 OEU11505.1 - 0.00026 21.1 0.2 0.00057 20.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Phage_NinH PF06322.11 OEU11506.1 - 0.28 11.1 0.9 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 Phage NinH protein DUF2061 PF09834.9 OEU11507.1 - 1.6e-17 63.7 9.5 1.8e-17 63.6 9.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) Hexapep PF00132.24 OEU11508.1 - 2.4e-09 36.6 3.2 0.00015 21.4 0.0 4.1 5 0 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OEU11508.1 - 0.023 14.4 4.4 4.3 7.2 3.2 3.4 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OEU11508.1 - 0.039 12.9 0.4 0.071 12.0 0.2 1.5 1 1 0 1 1 1 0 L-fucokinase Peptidase_M3 PF01432.20 OEU11509.1 - 3.1e-105 353.1 1.9 6.8e-105 352.0 1.9 1.5 1 0 0 1 1 1 1 Peptidase family M3 Octopine_DH PF02317.17 OEU11509.1 - 0.009 16.1 1.8 0.016 15.3 0.1 2.2 2 1 0 2 2 2 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Peptidase_M50B PF13398.6 OEU11509.1 - 0.13 11.9 0.5 0.24 11.0 0.5 1.4 1 0 0 1 1 1 0 Peptidase M50B-like SNF2_N PF00176.23 OEU11510.1 - 2.4e-64 217.3 0.2 3.4e-64 216.8 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU11510.1 - 3.2e-19 69.3 0.0 8.5e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU11510.1 - 2.1e-08 34.4 0.0 4.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU11510.1 - 2.4e-05 23.6 3.8 4.4e-05 22.8 0.4 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU11510.1 - 0.00057 19.7 0.0 0.0025 17.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OEU11510.1 - 0.0068 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 OEU11510.1 - 0.02 14.2 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OEU11510.1 - 0.036 14.4 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OEU11510.1 - 0.096 12.1 0.0 0.3 10.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein PigN PF04987.14 OEU11511.1 - 1.7 7.4 5.3 4.6 6.0 1.3 2.2 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Tmpp129 PF10272.9 OEU11512.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor 2OG-FeII_Oxy_3 PF13640.6 OEU11514.1 - 6.1e-05 23.8 0.4 0.00035 21.4 0.1 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 OEU11514.1 - 0.059 12.9 0.2 6.7 6.2 0.0 2.7 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA PEHE PF15275.6 OEU11515.1 - 0.00023 21.8 0.5 0.00023 21.8 0.5 6.0 7 0 0 7 7 7 2 PEHE domain ATP-synt_F PF01990.17 OEU11518.1 - 2.7e-33 114.2 0.1 3e-33 114.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PMSR PF01625.21 OEU11519.1 - 7.2e-06 26.3 0.8 1.7e-05 25.0 0.8 1.7 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase TAT_signal PF10518.9 OEU11519.1 - 0.014 15.2 0.6 0.024 14.5 0.6 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence LRR_8 PF13855.6 OEU11520.1 - 6.6e-21 73.8 11.5 4.5e-10 39.1 0.6 4.9 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OEU11520.1 - 5.8e-16 58.3 20.4 0.0016 18.8 2.3 6.0 2 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11520.1 - 1.8e-08 33.8 13.9 2.2 9.2 0.3 8.2 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU11520.1 - 0.0056 16.6 16.7 16 5.9 0.0 6.7 7 0 0 7 7 7 3 Leucine Rich repeat Peptidase_C48 PF02902.19 OEU11523.1 - 9.1e-06 25.7 1.0 4.7e-05 23.3 0.0 2.3 2 1 1 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain DUF3552 PF12072.8 OEU11523.1 - 1.1 8.6 11.2 2.9 7.3 11.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) YqzE PF14038.6 OEU11523.1 - 1.8 8.6 3.6 3.7 7.6 3.6 1.4 1 0 0 1 1 1 0 YqzE-like protein Mito_carr PF00153.27 OEU11524.1 - 1.6e-48 162.5 3.3 1.8e-15 56.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 OEU11524.1 - 0.058 13.5 0.0 0.45 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) DUF2781 PF10914.8 OEU11525.1 - 1.3e-28 100.2 5.4 1.7e-28 99.9 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ATP-synt_I PF03899.15 OEU11526.1 - 0.029 14.7 0.6 0.047 14.1 0.6 1.2 1 0 0 1 1 1 0 ATP synthase I chain CbiZ PF01955.18 OEU11526.1 - 0.055 13.6 1.1 0.093 12.8 1.1 1.2 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase LapA_dom PF06305.11 OEU11526.1 - 0.11 12.3 0.6 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Menin PF05053.13 OEU11527.1 - 7.7e-24 84.0 3.1 3.8e-22 78.5 0.1 2.8 3 0 0 3 3 3 2 Menin SUIM_assoc PF16619.5 OEU11527.1 - 0.031 14.3 6.0 0.083 13.0 6.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 OEU11529.1 - 1.1e-12 47.6 0.0 1.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH_1 PF00378.20 OEU11531.1 - 1.9e-22 79.8 0.4 2e-22 79.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU11531.1 - 8.8e-10 38.6 0.2 1e-09 38.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GCH_III PF05165.12 OEU11531.1 - 0.064 12.5 0.2 0.075 12.3 0.2 1.0 1 0 0 1 1 1 0 GTP cyclohydrolase III SAYSvFN PF10260.9 OEU11532.1 - 1.8e-08 34.1 0.1 2.5e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SVIP PF15811.5 OEU11532.1 - 0.072 13.6 4.6 0.11 13.0 4.6 1.3 1 0 0 1 1 1 0 Small VCP/p97-interacting protein BTB_2 PF02214.22 OEU11533.1 - 2.1e-08 34.4 0.3 6.8e-08 32.8 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain AP4E_app_platf PF14807.6 OEU11534.1 - 3.2e-17 62.7 0.0 4.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Adaptin_N PF01602.20 OEU11534.1 - 0.008 14.8 0.0 0.0094 14.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Adaptin_N PF01602.20 OEU11535.1 - 7.6e-72 242.5 0.1 9.5e-72 242.2 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OEU11535.1 - 2.8e-10 40.5 0.1 1.7e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OEU11535.1 - 3.9e-05 24.1 0.2 0.37 11.4 0.0 3.4 4 0 0 4 4 4 2 HEAT-like repeat TIP120 PF08623.10 OEU11535.1 - 0.00078 19.3 1.1 0.0088 15.8 0.1 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.7 OEU11535.1 - 0.0027 18.3 0.0 0.44 11.2 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OEU11535.1 - 0.03 14.6 0.2 4.6 7.8 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Prefoldin_2 PF01920.20 OEU11536.1 - 2.9e-18 65.8 0.5 3.4e-18 65.5 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 OEU11536.1 - 0.032 14.2 1.4 1.4 8.9 1.4 2.2 1 1 0 1 1 1 0 Prefoldin subunit Complex1_49kDa PF00346.19 OEU11536.1 - 0.05 12.7 0.1 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit FTA4 PF13093.6 OEU11536.1 - 0.061 13.2 3.6 0.036 13.9 1.8 1.5 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 E2 PF08199.11 OEU11536.1 - 0.18 11.7 0.2 0.4 10.7 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage E2-like protein PI3K_P85_iSH2 PF16454.5 OEU11536.1 - 0.27 10.8 4.4 1.3 8.6 1.6 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlaC_arch PF05377.11 OEU11536.1 - 0.37 11.2 3.8 1.7 9.1 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 OEU11536.1 - 0.63 10.3 5.8 1.3 9.2 0.3 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II PAH PF02671.21 OEU11537.1 - 8.4e-37 125.1 7.1 3.1e-18 65.6 2.9 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OEU11537.1 - 6.3e-34 116.0 0.1 2.4e-33 114.1 0.1 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 OEU11537.1 - 1.3e-20 74.3 1.3 4.8e-20 72.4 0.0 2.6 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein DUF3246 PF11596.8 OEU11537.1 - 0.26 10.7 7.0 0.023 14.1 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) Glutaredoxin PF00462.24 OEU11538.1 - 4.4e-16 58.9 0.1 6e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OEU11538.1 - 0.0069 16.8 0.5 0.0086 16.5 0.5 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 OEU11538.1 - 0.021 15.2 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 OEU11538.1 - 0.026 14.7 0.7 3.4 7.8 0.7 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 OEU11538.1 - 0.026 14.6 0.1 0.06 13.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin domain PT PF04886.12 OEU11539.1 - 0.004 16.7 79.8 0.0099 15.4 11.0 8.3 6 3 0 6 6 6 6 PT repeat REV PF00424.18 OEU11540.1 - 3.3 7.8 12.6 1.3 9.1 0.3 3.0 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) PEX11 PF05648.14 OEU11541.1 - 0.0029 17.1 0.2 0.0032 17.0 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ST7 PF04184.12 OEU11541.1 - 0.023 13.2 0.0 0.027 13.0 0.0 1.0 1 0 0 1 1 1 0 ST7 protein SieB PF14163.6 OEU11541.1 - 0.096 12.2 1.1 0.18 11.3 1.1 1.4 1 1 0 1 1 1 0 Super-infection exclusion protein B E3_UbLigase_R4 PF13764.6 OEU11542.1 - 1e-90 305.1 6.1 2.3e-46 158.4 0.2 3.8 3 1 0 3 3 3 2 E3 ubiquitin-protein ligase UBR4 SLC12 PF03522.15 OEU11542.1 - 0.12 11.4 12.1 0.62 9.0 0.2 2.7 3 0 0 3 3 3 0 Solute carrier family 12 DUF2828 PF11443.8 OEU11542.1 - 0.17 10.0 5.4 0.42 8.6 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3402 PF11882.8 OEU11542.1 - 0.98 8.5 15.0 0.89 8.6 3.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3402) DDHD PF02862.17 OEU11542.1 - 1.1 9.4 11.8 0.17 12.0 0.2 3.9 3 0 0 3 3 3 0 DDHD domain DUF5104 PF17117.5 OEU11542.1 - 1.2 9.6 4.6 2.8 8.4 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) CobT PF06213.12 OEU11542.1 - 3.8 6.8 15.6 0.18 11.2 7.3 2.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT MAP17 PF15807.5 OEU11542.1 - 5.6 7.2 9.4 39 4.5 9.4 2.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Connexin PF00029.19 OEU11542.1 - 9.9 5.8 5.9 29 4.3 5.9 1.8 1 0 0 1 1 1 0 Connexin PseudoU_synth_2 PF00849.22 OEU11543.1 - 9.5e-22 77.8 1.9 3.8e-21 75.8 1.9 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF5461 PF17545.2 OEU11543.1 - 0.0091 16.3 0.1 0.045 14.1 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5461) FSH1 PF03959.13 OEU11544.1 - 2.4e-15 56.8 1.1 1.9e-08 34.2 0.0 2.1 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Eaf7 PF07904.13 OEU11544.1 - 0.061 13.7 1.1 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 Abhydrolase_4 PF08386.10 OEU11544.1 - 0.068 13.3 0.1 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein HTH_50 PF18024.1 OEU11545.1 - 3.5e-06 26.5 0.1 0.0092 15.6 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_8 PF02954.19 OEU11545.1 - 0.03 14.1 2.7 0.26 11.1 0.5 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family zf-GRF PF06839.12 OEU11546.1 - 1.7e-06 28.0 2.9 1.7e-06 28.0 2.9 2.9 3 0 0 3 3 3 1 GRF zinc finger UIM PF02809.20 OEU11546.1 - 0.0053 16.6 0.2 0.019 14.9 0.2 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif Adeno_PV PF03910.13 OEU11546.1 - 4 6.1 6.4 10 4.7 6.4 1.6 1 0 0 1 1 1 0 Adenovirus minor core protein PV Trypsin PF00089.26 OEU11547.1 - 1.7e-21 77.1 1.2 2.1e-21 76.8 1.2 1.1 1 0 0 1 1 1 1 Trypsin H2TH PF06831.14 OEU11548.1 - 6.6e-20 70.9 0.0 1.6e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain HeH PF12949.7 OEU11548.1 - 3.7e-16 58.5 7.1 2.6e-08 33.4 0.1 3.8 4 0 0 4 4 4 2 HeH/LEM domain Fapy_DNA_glyco PF01149.24 OEU11548.1 - 3.9e-08 33.9 0.1 9.1e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Endonuc-dimeris PF09124.10 OEU11548.1 - 0.00081 19.5 0.4 0.36 11.0 0.2 2.7 2 0 0 2 2 2 2 T4 recombination endonuclease VII, dimerisation C1_1 PF00130.22 OEU11548.1 - 0.25 11.3 1.7 0.48 10.4 1.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.7 OEU11548.1 - 0.52 10.3 5.5 0.98 9.4 5.5 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4398 PF14346.6 OEU11548.1 - 5.5 7.7 12.0 16 6.2 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) 2OG-FeII_Oxy_2 PF13532.6 OEU11549.1 - 3.2e-18 66.6 0.1 3.6e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU11549.1 - 9.3e-06 26.1 0.0 1.1e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSF_DNA-bind PF00447.17 OEU11550.1 - 2.7e-15 56.7 0.0 3.1e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding RuBisCO_large_N PF02788.16 OEU11551.1 - 0.018 15.2 0.0 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain LIDHydrolase PF10230.9 OEU11552.1 - 0.0055 16.3 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 OEU11552.1 - 0.031 14.0 1.5 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family Thioesterase PF00975.20 OEU11552.1 - 0.18 11.9 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain MFS_1_like PF12832.7 OEU11553.1 - 5.6e-19 68.3 9.7 2.9e-17 62.6 5.1 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 OEU11553.1 - 1.5e-07 30.7 8.4 4.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OEU11553.1 - 6.2e-06 25.0 13.3 0.00035 19.3 7.0 2.0 2 0 0 2 2 2 2 MFS/sugar transport protein PilX_N PF14341.6 OEU11553.1 - 0.014 15.3 2.4 0.11 12.5 0.3 3.3 4 0 0 4 4 4 0 PilX N-terminal Sugar_tr PF00083.24 OEU11553.1 - 0.019 13.9 0.2 0.019 13.9 0.2 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter CD99L2 PF12301.8 OEU11553.1 - 0.33 11.2 7.2 0.3 11.4 0.7 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 PBP1_TM PF14812.6 OEU11553.1 - 4.3 7.8 5.6 3.7 8.0 0.2 2.7 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AhpC-TSA_2 PF13911.6 OEU11554.1 - 3.4e-09 36.8 0.0 6.5e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Cyc-maltodext_C PF10438.9 OEU11554.1 - 0.19 11.9 0.0 0.54 10.4 0.0 1.7 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain TRM PF02005.16 OEU11555.1 - 8.8e-101 337.8 0.0 2.5e-100 336.3 0.0 1.6 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 OEU11555.1 - 0.11 12.1 0.1 0.28 10.7 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase small domain DIOX_N PF14226.6 OEU11556.1 - 5.5e-28 98.1 0.0 1e-27 97.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OEU11556.1 - 6e-19 68.4 0.1 1.9e-17 63.6 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fasciclin PF02469.22 OEU11557.1 - 5.9e-10 39.5 0.0 0.00035 20.8 0.1 2.7 1 1 1 2 2 2 2 Fasciclin domain PT PF04886.12 OEU11557.1 - 0.0012 18.4 123.4 0.06 12.9 13.6 6.3 3 2 2 5 5 5 3 PT repeat Alanine_zipper PF11839.8 OEU11557.1 - 5.2 7.5 19.0 8.9 6.8 19.0 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF383 PF04063.14 OEU11558.1 - 0.065 12.9 0.0 0.84 9.3 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF383) DUF4258 PF14076.6 OEU11559.1 - 0.0088 16.4 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) Osteoregulin PF07175.11 OEU11559.1 - 0.067 13.4 2.9 0.72 10.0 0.4 2.5 1 1 1 2 2 2 0 Osteoregulin Methyltransf_21 PF05050.12 OEU11560.1 - 9.8e-06 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Baculo_E25 PF05274.11 OEU11560.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 SYCP2_ARLD PF18581.1 OEU11560.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain PsbQ PF05757.11 OEU11561.1 - 0.015 15.0 0.5 0.026 14.3 0.5 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) UCR_Fe-S_N PF10399.9 OEU11561.1 - 0.035 13.5 1.8 0.11 11.9 1.8 1.9 1 1 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal FTZ PF03867.14 OEU11561.1 - 0.43 10.1 5.8 0.12 11.9 1.8 1.8 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Keratin_2_head PF16208.5 OEU11562.1 - 1.5 9.0 33.8 4.3 7.4 16.8 2.1 1 1 1 2 2 2 0 Keratin type II head KRTAP PF11759.8 OEU11562.1 - 4.3 8.0 36.5 1.8e+04 -7.9 36.5 2.3 1 1 0 1 1 1 0 Keratin-associated matrix PT PF04886.12 OEU11563.1 - 1.6e-12 46.7 25.7 0.00047 19.6 25.7 2.5 1 1 0 1 1 1 1 PT repeat GDP_Man_Dehyd PF16363.5 OEU11564.1 - 0.00018 21.0 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OEU11566.1 - 3.2e-12 46.8 0.0 9.3e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AAA_lid_2 PF17863.1 OEU11568.1 - 0.017 14.9 1.3 0.031 14.1 1.3 1.4 1 0 0 1 1 1 0 AAA lid domain Lipase_GDSL_2 PF13472.6 OEU11573.1 - 4.6e-12 46.7 0.0 6.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU11573.1 - 4.1e-05 23.7 0.0 5.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HATPase_c PF02518.26 OEU11574.1 - 8.1e-20 71.4 0.3 1.8e-19 70.3 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OEU11574.1 - 9.3e-20 70.9 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OEU11574.1 - 1.6e-08 34.5 0.3 6.6e-08 32.5 0.1 2.2 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SWIB PF02201.18 OEU11575.1 - 5.3e-31 106.3 0.0 6.1e-31 106.1 0.0 1.0 1 0 0 1 1 1 1 SWIB/MDM2 domain PTR2 PF00854.21 OEU11576.1 - 2.7e-44 151.6 21.9 5e-27 94.7 3.3 2.2 1 1 1 2 2 2 2 POT family SNF PF00209.18 OEU11577.1 - 2.1e-85 287.4 45.0 2.3e-51 175.1 19.3 3.2 2 1 1 3 3 3 3 Sodium:neurotransmitter symporter family Fer2_3 PF13085.6 OEU11580.1 - 3.1e-31 107.6 0.0 5.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OEU11580.1 - 8e-10 39.1 5.9 8e-10 39.1 5.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OEU11580.1 - 2.9e-08 34.0 7.2 2.9e-08 34.0 7.2 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OEU11580.1 - 8.1e-08 32.3 4.0 8.1e-08 32.3 4.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OEU11580.1 - 0.0015 18.5 0.3 0.0015 18.5 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 OEU11580.1 - 0.0019 18.4 1.2 0.45 10.7 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OEU11580.1 - 0.0095 16.1 7.5 0.0095 16.1 7.5 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OEU11580.1 - 0.031 14.9 9.4 0.031 14.9 9.4 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Ldh_2 PF02615.14 OEU11581.1 - 1.2e-77 261.3 0.1 9.3e-77 258.4 0.1 2.0 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF3439 PF11921.8 OEU11581.1 - 0.43 10.5 5.4 0.075 13.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Aldedh PF00171.22 OEU11582.1 - 1.9e-129 432.2 0.0 2.3e-129 431.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 OEU11583.1 - 3.3e-15 55.9 47.0 4.5e-13 48.9 23.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OEU11583.1 - 4.6e-09 36.1 8.0 4.6e-09 36.1 8.0 2.1 2 0 0 2 2 2 1 Nodulin-like DUF3494 PF11999.8 OEU11584.1 - 1.1e-53 181.9 21.5 1.4e-53 181.7 21.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU11585.1 - 7.3e-58 195.6 17.3 9e-58 195.3 17.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) ABC2_membrane_3 PF12698.7 OEU11586.1 - 2.1e-55 188.2 32.7 4.1e-38 131.4 12.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 OEU11586.1 - 6.8e-54 182.1 0.0 1.7e-29 103.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU11586.1 - 1.2e-15 58.2 0.0 4.1e-05 23.5 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 OEU11586.1 - 0.001 18.7 4.1 0.33 10.5 0.5 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_15 PF13175.6 OEU11586.1 - 0.006 16.3 0.1 0.53 9.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 OEU11586.1 - 0.012 15.5 1.9 0.016 15.2 0.2 1.9 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 OEU11586.1 - 0.014 14.7 0.8 0.54 9.5 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.6 OEU11586.1 - 0.027 14.8 0.1 2 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OEU11586.1 - 0.03 14.0 2.2 1.3 8.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 OEU11586.1 - 0.039 13.4 0.0 12 5.2 0.0 3.3 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OEU11586.1 - 0.049 13.4 2.7 0.38 10.5 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MukB PF04310.12 OEU11586.1 - 0.057 13.2 2.1 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_16 PF13191.6 OEU11586.1 - 0.13 12.6 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 OEU11586.1 - 0.25 11.8 12.5 0.031 14.8 0.8 3.4 3 1 0 3 3 2 0 AAA domain zf-C3HC4_3 PF13920.6 OEU11588.1 - 2e-07 30.7 6.2 2e-07 30.7 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU11588.1 - 0.00011 22.0 7.4 0.00011 22.0 7.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 NTF2 PF02136.20 OEU11588.1 - 0.0015 19.1 0.2 1.3 9.6 0.0 3.0 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain Peptidase_M6 PF05547.11 OEU11592.1 - 3.5e-13 48.8 10.9 8.4e-12 44.2 10.9 2.3 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 EF-hand_5 PF13202.6 OEU11592.1 - 0.051 13.1 0.2 0.15 11.6 0.2 1.9 1 0 0 1 1 1 0 EF hand Peptidase_M4 PF01447.18 OEU11592.1 - 0.059 13.9 3.5 0.079 13.5 0.3 2.3 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain EF-hand_1 PF00036.32 OEU11592.1 - 0.18 11.4 0.6 0.83 9.3 0.2 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 OEU11592.1 - 0.24 11.4 1.3 0.72 9.9 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain YdaT_toxin PF06254.11 OEU11594.1 - 0.13 12.9 0.0 0.48 11.0 0.0 2.0 1 0 0 1 1 1 0 Putative bacterial toxin ydaT PHD PF00628.29 OEU11599.1 - 1.3e-06 28.1 4.0 5.1e-06 26.3 4.0 2.0 1 0 0 1 1 1 1 PHD-finger DHBP_synthase PF00926.19 OEU11600.1 - 3.3e-78 261.6 0.6 5.6e-78 260.9 0.6 1.4 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 OEU11600.1 - 1.4e-33 115.8 0.2 6e-33 113.7 0.1 2.0 2 0 0 2 2 2 1 GTP cyclohydrolase II zf-C3HC4_3 PF13920.6 OEU11601.1 - 0.0075 16.1 13.0 0.015 15.1 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU11601.1 - 0.0082 16.1 14.8 0.018 15.0 14.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU11601.1 - 0.034 14.0 11.5 0.076 12.9 11.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OEU11601.1 - 0.083 12.8 5.7 0.15 11.9 5.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 OEU11601.1 - 0.4 10.8 9.3 0.9 9.7 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_2 PF13639.6 OEU11601.1 - 1.6 9.2 13.8 2.9 8.3 13.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 OEU11601.1 - 5.2 7.0 15.1 11 5.9 15.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU11601.1 - 9.3 6.2 13.7 19 5.2 13.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CCDC24 PF15669.5 OEU11602.1 - 0.067 13.0 16.1 0.19 11.6 1.0 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family IBR PF01485.21 OEU11602.1 - 0.21 11.8 1.8 0.44 10.8 1.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Pyr_redox_2 PF07992.14 OEU11603.1 - 0.0046 16.2 0.0 0.0051 16.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU11604.1 - 7.3e-10 38.9 0.3 1.6e-09 37.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU11604.1 - 4.7e-07 29.7 0.3 7.2e-07 29.1 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU11604.1 - 0.0014 18.0 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU11604.1 - 0.0019 18.2 0.1 0.0037 17.3 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OEU11604.1 - 0.047 14.3 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OEU11604.1 - 0.085 11.4 0.0 3.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) zf-MYND PF01753.18 OEU11606.1 - 2.7e-06 27.4 10.9 2.7e-06 27.4 10.9 1.9 2 0 0 2 2 2 1 MYND finger Ran_BP1 PF00638.18 OEU11607.1 - 5.6e-38 129.9 0.1 6.9e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 RanBP1 domain PH_15 PF17339.2 OEU11607.1 - 0.0017 18.2 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 PH domain WH1 PF00568.23 OEU11607.1 - 0.024 14.6 0.3 0.057 13.4 0.3 1.7 1 1 0 1 1 1 0 WH1 domain Asp_protease_2 PF13650.6 OEU11608.1 - 0.00052 20.6 0.0 0.0014 19.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OEU11608.1 - 0.023 15.3 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OEU11608.1 - 0.18 12.1 0.4 1.5 9.2 0.1 2.6 2 1 0 2 2 2 0 Retroviral aspartyl protease DDE_Tnp_1_7 PF13843.6 OEU11609.1 - 2.4e-15 56.7 0.0 3.3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Rubredoxin_2 PF18073.1 OEU11610.1 - 0.082 12.6 1.1 0.16 11.7 1.1 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain Cys_Met_Meta_PP PF01053.20 OEU11611.1 - 9.6e-89 297.6 0.0 8.8e-83 278.0 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme HA PF03457.14 OEU11612.1 - 5.7e-29 100.2 7.6 1.6e-13 50.7 0.5 3.1 3 0 0 3 3 3 3 Helicase associated domain DUF4080 PF13311.6 OEU11612.1 - 0.095 12.9 4.5 0.12 12.6 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4080) Gly_transf_sug PF04488.15 OEU11614.1 - 5.4e-09 36.6 0.3 1.3e-08 35.3 0.3 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU11614.1 - 3.1e-07 30.0 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain zf-C2H2 PF00096.26 OEU11616.1 - 5e-06 26.7 5.9 0.0032 17.8 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OEU11616.1 - 2.1e-05 25.0 5.1 0.038 14.8 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OEU11616.1 - 0.051 13.5 3.9 5.7 7.0 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 OEU11616.1 - 0.31 11.4 4.3 5 7.5 4.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 OEU11616.1 - 0.41 10.7 4.8 2.5 8.2 1.0 2.4 2 0 0 2 2 2 0 BED zinc finger Toxin_TOLIP PF00087.21 OEU11616.1 - 0.89 9.9 7.1 2.8 8.3 1.6 2.3 1 1 1 2 2 2 0 Snake toxin and toxin-like protein zf-CHCC PF10276.9 OEU11616.1 - 1.2 9.3 4.5 0.88 9.7 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_6 PF13912.6 OEU11616.1 - 2.3 8.3 6.2 3.4 7.8 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger MREG PF15812.5 OEU11617.1 - 0.053 13.8 0.2 0.09 13.1 0.2 1.4 1 0 0 1 1 1 0 Melanoregulin Topo-VIb_trans PF09239.11 OEU11618.1 - 7.2e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer Sec62 PF03839.16 OEU11619.1 - 0.19 11.2 4.2 0.2 11.1 4.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1517 PF07466.11 OEU11621.1 - 0.47 10.6 7.6 0.22 11.6 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) PARM PF17061.5 OEU11621.1 - 0.94 9.6 5.4 1.5 8.9 5.4 1.3 1 0 0 1 1 1 0 PARM PAN_1 PF00024.26 OEU11622.1 - 0.11 12.4 14.5 0.19 11.7 1.8 2.7 1 1 1 2 2 2 0 PAN domain Sigma_reg_N PF13800.6 OEU11622.1 - 0.13 12.6 1.5 0.24 11.7 1.5 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PAN_3 PF08277.12 OEU11622.1 - 0.25 11.2 11.1 0.04 13.7 3.4 2.5 2 0 0 2 2 2 0 PAN-like domain PAN_4 PF14295.6 OEU11622.1 - 2 8.4 17.5 1.3 9.0 2.4 2.8 3 0 0 3 3 3 0 PAN domain MANEC PF07502.14 OEU11622.1 - 4.9 7.5 13.5 3.2 8.1 0.7 3.2 3 1 0 3 3 3 0 MANEC domain 2-Hacid_dh_C PF02826.19 OEU11623.1 - 6.7e-53 178.7 0.0 9.3e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OEU11623.1 - 0.00025 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 OEU11623.1 - 0.0049 17.1 0.0 0.0067 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.21 OEU11623.1 - 0.0051 16.6 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.17 OEU11623.1 - 0.0081 16.7 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OEU11623.1 - 0.0084 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Gp_dh_N PF00044.24 OEU11623.1 - 0.035 14.4 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IlvN PF07991.12 OEU11623.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 OEU11623.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 OEU11623.1 - 0.2 12.2 0.0 0.43 11.1 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain Ank_2 PF12796.7 OEU11624.1 - 5e-18 65.5 0.0 4.3e-11 43.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU11624.1 - 1.1e-11 44.7 0.0 0.0037 17.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OEU11624.1 - 2.3e-11 42.8 0.2 0.13 12.9 0.1 4.1 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OEU11624.1 - 4.1e-06 27.2 0.2 0.065 13.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU11624.1 - 2.7e-05 24.3 0.0 6.8 7.1 0.0 4.6 4 1 1 5 5 5 1 Ankyrin repeats (many copies) eRF1_2 PF03464.15 OEU11625.1 - 2.1e-44 151.1 0.0 4.1e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OEU11625.1 - 3.7e-37 127.3 0.6 7.4e-37 126.3 0.2 1.7 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 OEU11625.1 - 8.2e-21 74.3 0.0 1.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 OEU11625.1 - 4.2e-09 36.8 0.0 6.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OEU11625.1 - 3.3e-08 33.9 0.0 5.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF2214 PF09980.9 OEU11626.1 - 0.23 11.3 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) PseudoU_synth_2 PF00849.22 OEU11627.1 - 7e-29 101.0 0.1 8.5e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase ADPrib_exo_Tox PF03496.14 OEU11627.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Ribosomal_L11_N PF03946.14 OEU11628.1 - 1.5e-21 76.0 0.0 2.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OEU11628.1 - 1.2e-19 70.6 0.0 2.4e-19 69.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain HHH PF00633.23 OEU11629.1 - 0.23 11.4 0.1 0.51 10.3 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2946 PF11162.8 OEU11630.1 - 0.17 12.6 6.8 0.46 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) K_channel_TID PF07941.11 OEU11630.1 - 1.2 9.6 9.3 13 6.3 0.2 3.2 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain LRR_4 PF12799.7 OEU11631.1 - 0.018 15.5 0.5 0.42 11.1 0.5 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU11631.1 - 0.067 13.0 0.3 0.2 11.5 0.3 1.8 1 0 0 1 1 1 0 Leucine rich repeat LIP PF03583.14 OEU11632.1 - 0.15 11.3 0.1 1.1 8.5 0.0 2.3 3 1 1 4 4 4 0 Secretory lipase LRR_8 PF13855.6 OEU11634.1 - 1.7e-11 43.7 26.2 3.6e-07 29.9 0.7 5.7 6 0 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 OEU11634.1 - 4.3e-10 39.7 24.2 4.1e-05 23.9 0.3 5.5 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11634.1 - 0.0065 16.9 24.9 0.065 13.8 0.5 7.3 7 0 0 7 7 7 2 Leucine Rich Repeat CX9C PF16860.5 OEU11635.1 - 0.031 14.3 3.1 0.052 13.6 3.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 OEU11635.1 - 0.031 14.5 3.0 0.047 13.9 3.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 OEU11635.1 - 0.059 13.5 5.2 0.1 12.8 5.2 1.4 1 0 0 1 1 1 0 CHCH domain DUF1251 PF06856.11 OEU11635.1 - 0.078 12.7 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) zf-CCHC_4 PF14392.6 OEU11635.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Zinc knuckle PPR_2 PF13041.6 OEU11636.1 - 1.2e-21 76.7 0.6 0.0001 22.4 0.1 6.9 5 1 1 6 6 6 4 PPR repeat family PPR_1 PF12854.7 OEU11636.1 - 3.6e-20 71.4 7.5 0.00043 19.9 0.0 8.8 8 3 0 8 8 8 5 PPR repeat PPR_3 PF13812.6 OEU11636.1 - 2.4e-15 56.4 0.1 0.0035 17.4 0.0 7.2 6 1 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 OEU11636.1 - 1.5e-07 31.2 20.0 0.066 13.5 0.1 8.5 8 3 0 8 8 8 3 PPR repeat F1F0-ATPsyn_F PF10791.9 OEU11636.1 - 0.016 15.6 0.0 0.14 12.6 0.0 2.4 2 1 1 3 3 3 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Wzy_C_2 PF11846.8 OEU11636.1 - 0.12 12.2 0.7 4.4 7.2 0.1 3.0 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Hpt PF01627.23 OEU11637.1 - 1.6e-08 34.7 0.2 2.3e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Hpt domain T3SS_needle_F PF09392.10 OEU11637.1 - 0.067 13.4 1.5 0.23 11.7 0.8 2.1 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CBS PF00571.28 OEU11638.1 - 0.041 14.3 0.0 7.3 7.1 0.0 2.8 3 0 0 3 3 3 0 CBS domain DUF2726 PF10881.8 OEU11638.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) DUF1043 PF06295.12 OEU11638.1 - 0.26 11.3 2.3 0.66 10.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) SDA1 PF05285.12 OEU11641.1 - 0.4 10.1 15.7 0.5 9.7 15.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OEU11641.1 - 1.7 6.8 13.6 2.1 6.5 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 OEU11641.1 - 6.4 5.1 13.9 7.4 4.9 13.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 ERCC4 PF02732.15 OEU11642.1 - 1.9e-10 41.1 0.1 7.6e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain SAP PF02037.27 OEU11642.1 - 5.3e-06 26.1 0.1 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain DUF600 PF04634.12 OEU11642.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF600 CENP-B_dimeris PF09026.10 OEU11644.1 - 0.042 14.2 1.3 0.042 14.2 1.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MAM33 PF02330.16 OEU11644.1 - 1.3 8.9 8.1 7.3 6.5 0.9 3.0 3 0 0 3 3 3 0 Mitochondrial glycoprotein Adeno_E3_CR2 PF02439.15 OEU11644.1 - 1.4 8.7 4.7 3.4 7.5 4.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PBP1_TM PF14812.6 OEU11644.1 - 2.2 8.7 0.0 2.2 8.7 0.0 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal XRN_N PF03159.18 OEU11645.1 - 3.5e-30 105.2 0.0 3.8e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus HI0933_like PF03486.14 OEU11646.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Metallophos PF00149.28 OEU11648.1 - 1.4e-05 25.7 0.4 0.00011 22.7 0.3 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Rrp44_CSD1 PF17216.3 OEU11648.1 - 0.15 11.8 0.1 0.15 11.8 0.1 5.2 5 1 0 5 5 5 0 Rrp44-like cold shock domain Peptidase_C15 PF01470.17 OEU11649.1 - 8.4e-55 186.1 0.0 7.4e-46 156.9 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase DUF1415 PF07209.12 OEU11650.1 - 5.6e-12 45.7 0.1 9.8e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) ubiquitin PF00240.23 OEU11651.1 - 1.2e-06 28.2 0.6 8.7e-06 25.4 0.4 2.4 2 1 0 2 2 2 1 Ubiquitin family DUF3361 PF11841.8 OEU11651.1 - 0.023 14.6 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) LRR_8 PF13855.6 OEU11651.1 - 0.037 13.8 1.2 0.61 9.9 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 OEU11651.1 - 0.36 11.3 16.1 0.44 11.0 0.3 5.3 3 3 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU11651.1 - 8.9 7.3 9.7 34 5.5 0.3 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat Ribosomal_L12_N PF16320.5 OEU11652.1 - 2.1 8.1 15.9 4.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Hydrolase_4 PF12146.8 OEU11653.1 - 5.2e-06 25.9 0.0 9.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 OEU11653.1 - 8.3e-05 21.9 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 OEU11653.1 - 0.004 16.7 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OEU11653.1 - 0.044 13.5 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 OEU11653.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_6 PF12697.7 OEU11653.1 - 0.12 13.0 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.7 OEU11657.1 - 0.0034 17.3 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OEU11657.1 - 0.025 14.4 0.1 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 F-box F-box PF00646.33 OEU11657.1 - 0.066 13.1 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 OEU11659.1 - 0.011 16.3 0.2 0.049 14.2 0.1 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) NopRA1 PF16201.5 OEU11659.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 tRNA_edit PF04073.15 OEU11660.1 - 7.6e-15 55.1 0.0 9.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Trypsin PF00089.26 OEU11661.1 - 4.4e-35 121.5 0.2 1.3e-17 64.4 0.0 2.7 2 1 1 3 3 3 2 Trypsin Trypsin_2 PF13365.6 OEU11661.1 - 0.0028 18.6 0.0 0.014 16.3 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-C3HC4_2 PF13923.6 OEU11662.1 - 0.00086 19.1 2.9 0.002 18.0 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU11662.1 - 0.014 15.4 6.5 0.035 14.1 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OEU11662.1 - 0.052 13.4 7.9 0.12 12.2 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU11662.1 - 0.3 11.5 7.0 0.75 10.2 7.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 OEU11662.1 - 0.39 10.9 4.3 0.87 9.8 4.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OEU11662.1 - 1.3 9.1 7.6 3.4 7.7 7.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Methyltransf_32 PF13679.6 OEU11664.1 - 2.6e-08 34.0 0.5 2.6e-08 34.0 0.5 2.2 3 0 0 3 3 3 1 Methyltransferase domain OTU PF02338.19 OEU11665.1 - 1.1e-11 45.3 0.2 4.3e-11 43.4 0.2 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease F-box-like PF12937.7 OEU11666.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like PolyA_pol PF01743.20 OEU11668.1 - 0.052 14.0 0.0 0.089 13.2 0.0 1.5 1 1 0 1 1 1 0 Poly A polymerase head domain zf-RanBP PF00641.18 OEU11669.1 - 1.3e-05 24.4 10.8 0.0053 16.0 5.8 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Ribonuc_L-PSP PF01042.21 OEU11670.1 - 0.048 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP Ran_BP1 PF00638.18 OEU11672.1 - 0.002 18.4 0.1 0.0092 16.2 0.0 2.0 1 1 1 2 2 2 1 RanBP1 domain Peptidase_M6 PF05547.11 OEU11673.1 - 2.7e-20 72.3 5.8 5.6e-20 71.3 5.8 1.5 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Peptidase_M10 PF00413.24 OEU11673.1 - 0.039 13.8 1.6 0.17 11.7 1.6 2.0 1 1 0 1 1 1 0 Matrixin BTB_2 PF02214.22 OEU11674.1 - 4.5e-08 33.3 0.0 3.6e-07 30.5 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain CC2-LZ PF16516.5 OEU11674.1 - 0.025 14.9 0.2 0.042 14.2 0.2 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BTB_3 PF16017.5 OEU11674.1 - 0.027 14.6 0.0 0.093 12.8 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain P22_CoatProtein PF11651.8 OEU11674.1 - 0.11 11.1 0.3 0.19 10.3 0.0 1.4 2 0 0 2 2 2 0 P22 coat protein - gene protein 5 CCDC158 PF15921.5 OEU11674.1 - 0.16 9.7 0.1 0.22 9.3 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 TPR_12 PF13424.6 OEU11674.1 - 0.2 11.9 0.4 0.37 11.1 0.4 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5320 PF17253.2 OEU11674.1 - 0.37 11.9 1.9 7 7.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DDE_Tnp_1_7 PF13843.6 OEU11675.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Transposase IS4 SP_C-Propep PF08999.10 OEU11675.1 - 1.4 8.7 5.7 2.6 7.9 5.7 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Carn_acyltransf PF00755.20 OEU11676.1 - 5.5e-176 586.7 0.0 7.1e-176 586.3 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fer4_12 PF13353.6 OEU11678.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain Aa_trans PF01490.18 OEU11679.1 - 1.3e-28 99.8 36.8 1.8e-27 96.1 36.8 2.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Rhodanese_C PF12368.8 OEU11680.1 - 5.9e-13 49.0 9.7 1.1e-12 48.1 9.7 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 OEU11680.1 - 1.8e-08 34.6 0.0 4.7e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OEU11680.1 - 6.3e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain MADF_DNA_bdg PF10545.9 OEU11680.1 - 0.02 15.2 1.0 0.042 14.2 1.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Sec1 PF00995.23 OEU11680.1 - 0.041 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Helicase_C PF00271.31 OEU11681.1 - 3.3e-14 53.2 0.0 3.3e-14 53.2 0.0 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HA2 PF04408.23 OEU11681.1 - 6.3e-11 42.5 0.0 6.3e-11 42.5 0.0 4.4 5 0 0 5 5 5 1 Helicase associated domain (HA2) DEAD PF00270.29 OEU11681.1 - 1.1e-06 28.5 0.2 3.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SprA-related PF12118.8 OEU11681.1 - 0.00045 19.5 10.3 0.00045 19.5 10.3 2.7 2 0 0 2 2 2 1 SprA-related family Cwf_Cwc_15 PF04889.12 OEU11681.1 - 0.001 18.9 7.1 0.001 18.9 7.1 3.7 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein AAA_22 PF13401.6 OEU11681.1 - 0.006 16.8 4.0 0.03 14.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OEU11681.1 - 0.016 14.3 0.3 0.038 13.1 0.3 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 OEU11681.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 KaiC IRK_C PF17655.1 OEU11682.1 - 6e-13 48.8 4.3 4.3e-07 29.7 0.0 2.8 2 1 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OEU11682.1 - 0.0004 20.2 0.9 0.00073 19.4 0.9 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain zf-C2H2_9 PF16293.5 OEU11682.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 OEU11682.1 - 0.073 13.6 0.0 0.32 11.5 0.0 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pneumo_phosprot PF02478.16 OEU11682.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus phosphoprotein zf-C2H2_4 PF13894.6 OEU11682.1 - 0.39 11.7 0.0 0.39 11.7 0.0 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 OEU11683.1 - 0.0011 18.9 0.2 0.0023 17.9 0.2 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RRN7 PF11781.8 OEU11683.1 - 0.0075 15.9 4.4 0.0075 15.9 4.4 2.2 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 OEU11683.1 - 0.14 11.7 2.1 0.52 9.9 2.1 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding Glyoxalase PF00903.25 OEU11684.1 - 1.8e-05 24.9 0.0 5.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OEU11684.1 - 0.00085 19.6 0.0 0.0022 18.2 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_transf_49 PF13896.6 OEU11685.1 - 1.3e-24 87.1 4.2 2e-18 66.8 0.0 2.9 3 1 0 3 3 3 2 Glycosyl-transferase for dystroglycan RNA_pol_Rpc4 PF05132.14 OEU11685.1 - 0.067 13.6 1.8 0.44 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 OEU11685.1 - 0.14 11.3 9.6 0.19 10.9 1.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter TLP-20 PF06088.11 OEU11685.1 - 0.91 9.4 6.7 0.082 12.8 1.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PRC2_HTH_1 PF18118.1 OEU11685.1 - 1.3 9.9 8.7 1.2 10.0 0.3 2.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Connexin PF00029.19 OEU11685.1 - 2.1 8.0 5.1 4.8 6.9 1.4 2.3 2 0 0 2 2 2 0 Connexin DUF3408 PF11888.8 OEU11685.1 - 3.9 7.6 10.7 11 6.2 6.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DHHC PF01529.20 OEU11686.1 - 1.2e-26 93.4 0.5 1.6e-26 93.0 0.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase PH PF00169.29 OEU11687.1 - 0.0058 17.1 0.0 0.028 14.9 0.0 2.2 1 0 0 1 1 1 1 PH domain Hydrolase PF00702.26 OEU11688.1 - 1.4e-10 41.8 0.0 1.6e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OEU11688.1 - 5.5e-09 36.3 0.0 3.1e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RNR_Alpha PF17975.1 OEU11688.1 - 0.00051 20.5 0.1 0.00094 19.6 0.1 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Hydrolase_like PF13242.6 OEU11688.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like GrpE PF01025.19 OEU11688.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 GrpE ESM4 PF15952.5 OEU11689.1 - 0.0051 17.3 2.9 0.0051 17.3 2.9 3.5 3 1 1 4 4 4 1 Enhancer of split M4 family DUF4258 PF14076.6 OEU11689.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Mo25 PF08569.11 OEU11689.1 - 0.039 13.3 2.5 0.075 12.4 2.5 1.4 1 0 0 1 1 1 0 Mo25-like Glyco_transf_49 PF13896.6 OEU11690.1 - 4.6e-34 118.2 0.8 4.8e-29 101.8 0.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF2755 PF10954.8 OEU11690.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Apc13p PF05839.11 OEU11690.1 - 0.11 12.7 0.0 9.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Apc13p protein Peptidase_M11 PF05548.11 OEU11691.1 - 4e-08 32.8 0.1 2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Gametolysin peptidase M11 CPSase_L_D2 PF02786.17 OEU11692.1 - 4.3e-50 170.2 0.2 8.7e-24 84.2 0.1 3.4 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OEU11692.1 - 8.9e-34 116.4 0.0 2.3e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OEU11692.1 - 2.3e-27 95.2 0.0 2.2e-26 92.1 0.0 2.6 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OEU11692.1 - 8.1e-19 67.2 0.6 4.1e-18 65.0 0.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme PCC_BT PF18140.1 OEU11692.1 - 1e-06 29.1 0.0 3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 OEU11692.1 - 0.00046 19.8 0.0 0.00088 18.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 OEU11692.1 - 0.0082 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 OEU11692.1 - 0.1 12.4 0.0 0.93 9.4 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.6 OEU11692.1 - 0.14 12.2 0.0 0.6 10.1 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Carb_kinase PF01256.17 OEU11692.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate kinase ATP-synt_ab_Xtn PF16886.5 OEU11692.1 - 0.18 11.7 0.2 0.48 10.3 0.2 1.7 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension DnaJ PF00226.31 OEU11693.1 - 3.6e-22 78.3 0.6 8.3e-22 77.1 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Gastrin PF00918.17 OEU11693.1 - 1.3 10.0 9.1 0.9 10.5 4.6 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family MFS_1 PF07690.16 OEU11694.1 - 1.6e-14 53.6 34.9 5.1e-14 52.0 25.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OEU11694.1 - 2.7e-12 45.9 5.6 2.7e-12 45.9 5.6 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Cytomega_UL20A PF05984.12 OEU11696.1 - 0.18 12.1 0.8 0.29 11.4 0.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein CofC PF01983.16 OEU11696.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like Keratin_B2_2 PF13885.6 OEU11696.1 - 1.3 9.0 27.8 1.2 9.1 25.5 1.9 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Pro_isomerase PF00160.21 OEU11697.1 - 9.1e-07 29.3 1.5 9.2e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SUIM_assoc PF16619.5 OEU11697.1 - 1.3 9.1 10.3 5.2 7.2 10.3 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 aGPT-Pplase1 PF18723.1 OEU11698.1 - 0.0017 17.8 0.0 0.0085 15.6 0.0 2.0 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 HA PF03457.14 OEU11699.1 - 4.9e-34 116.5 5.4 1.9e-19 69.7 0.7 2.4 2 0 0 2 2 2 2 Helicase associated domain UFD1 PF03152.14 OEU11699.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin fusion degradation protein UFD1 FKBP_C PF00254.28 OEU11700.1 - 7.4e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase YrhC PF14143.6 OEU11700.1 - 0.081 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 YrhC-like protein Sulfatase PF00884.23 OEU11701.1 - 2.6e-21 76.4 2.5 3.2e-21 76.0 2.5 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU11701.1 - 0.0063 16.2 1.2 0.0075 15.9 1.2 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TMEM51 PF15345.6 OEU11702.1 - 0.039 13.8 0.1 0.048 13.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Utp14 PF04615.13 OEU11703.1 - 0.02 13.5 37.8 0.024 13.2 37.8 1.0 1 0 0 1 1 1 0 Utp14 protein BTB_2 PF02214.22 OEU11704.1 - 0.0016 18.8 0.0 0.0047 17.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Zn_ribbon_2 PF12674.7 OEU11705.1 - 0.0087 16.7 0.9 0.0087 16.7 0.9 1.9 1 1 1 2 2 2 1 Putative zinc ribbon domain DUF5620 PF18522.1 OEU11705.1 - 0.077 13.4 0.1 0.57 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5620) Amidase PF01425.21 OEU11706.1 - 7.8e-85 285.5 0.2 4.2e-69 233.6 0.2 2.1 1 1 1 2 2 2 2 Amidase Fasciclin PF02469.22 OEU11706.1 - 5.1e-10 39.7 0.0 8.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Sulfotransfer_2 PF03567.14 OEU11707.1 - 2.3e-11 44.1 4.4 2.3e-11 44.1 4.4 2.8 2 1 0 2 2 2 1 Sulfotransferase family CPDase PF07823.11 OEU11708.1 - 1.1e-15 57.8 0.1 2.5e-15 56.7 0.1 1.6 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OEU11708.1 - 1.4e-06 28.3 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 OEU11708.1 - 0.05 13.8 0.1 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF4520 PF15016.6 OEU11709.1 - 0.0016 18.5 0.1 0.11 12.6 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4520) Aa_trans PF01490.18 OEU11710.1 - 1.3e-61 208.6 29.4 1.7e-61 208.2 29.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1494 PF07379.11 OEU11710.1 - 0.039 13.8 0.4 0.075 12.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) LRR_6 PF13516.6 OEU11711.1 - 0.018 15.1 7.2 1.2 9.4 0.8 3.5 2 1 0 2 2 2 0 Leucine Rich repeat LRR_8 PF13855.6 OEU11711.1 - 0.035 13.9 3.7 0.47 10.2 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 OEU11711.1 - 0.14 12.6 0.2 0.14 12.6 0.2 4.2 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) ArlS_N PF18719.1 OEU11711.1 - 0.31 11.3 4.2 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 ArlS sensor domain LRR_1 PF00560.33 OEU11711.1 - 1.7 9.5 10.3 20 6.2 0.3 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat HA PF03457.14 OEU11712.1 - 5.1e-61 202.9 5.1 2.6e-20 72.5 0.3 3.1 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU11712.1 - 0.00046 20.2 0.4 7.1 6.8 0.0 3.4 3 0 0 3 3 3 2 Transcriptional regulation of mitochondrial recombination Sortilin-Vps10 PF15902.5 OEU11712.1 - 0.021 13.6 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, LRR_4 PF12799.7 OEU11713.1 - 2.6e-05 24.5 10.9 0.48 10.9 0.2 4.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU11713.1 - 0.12 12.4 10.0 3.9 7.8 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OEU11713.1 - 5.5 7.9 8.1 30 5.7 0.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat TSC22 PF01166.18 OEU11714.1 - 2.9e-05 24.3 2.6 1.7 9.0 0.2 3.7 3 0 0 3 3 3 3 TSC-22/dip/bun family MRF_C1 PF13887.6 OEU11714.1 - 0.007 15.5 2.7 13 5.1 0.0 3.8 3 0 0 3 3 3 2 Myelin gene regulatory factor -C-terminal domain 1 DUF484 PF04340.12 OEU11714.1 - 0.075 12.7 0.4 4.5 6.9 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function, DUF484 BMFP PF04380.13 OEU11714.1 - 0.22 12.0 5.3 34 5.0 0.1 3.8 4 0 0 4 4 4 0 Membrane fusogenic activity Sugarporin_N PF11471.8 OEU11714.1 - 0.58 10.2 8.7 6.8 6.7 0.2 4.0 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension bZIP_2 PF07716.15 OEU11714.1 - 2 8.6 8.6 55 4.0 0.2 4.5 4 0 0 4 4 4 0 Basic region leucine zipper PhoD PF09423.10 OEU11716.1 - 0.00085 18.4 0.1 0.0014 17.7 0.1 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase GMC_oxred_N PF00732.19 OEU11717.1 - 3.3e-31 108.8 0.0 7.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OEU11717.1 - 1.1e-20 74.6 0.0 3e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OEU11717.1 - 0.019 15.2 0.1 0.05 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4144 PF13642.6 OEU11717.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 protein structure with unknown function DLH PF01738.18 OEU11718.1 - 7.6e-10 38.7 0.0 9e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family RE_EcoO109I PF14511.6 OEU11718.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I DUF805 PF05656.14 OEU11719.1 - 0.079 13.4 0.1 0.097 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3172 PF11371.8 OEU11719.1 - 0.13 11.9 0.1 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) Bestrophin PF01062.21 OEU11720.1 - 1.2e-29 103.6 0.9 1.8e-29 103.1 0.9 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2374 PF09574.10 OEU11720.1 - 0.0073 16.1 3.9 0.059 13.2 0.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (Duf2374) Iwr1 PF08574.10 OEU11720.1 - 0.2 12.7 7.1 0.29 12.2 4.0 2.3 2 0 0 2 2 2 0 Transcription factor Iwr1 Dirigent PF03018.14 OEU11721.1 - 0.017 14.9 0.4 0.033 14.0 0.4 1.4 1 0 0 1 1 1 0 Dirigent-like protein Na_H_Exchanger PF00999.21 OEU11722.1 - 3.7e-58 197.2 30.9 5.3e-58 196.6 30.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ABC_tran PF00005.27 OEU11723.1 - 5.7e-46 156.4 0.2 4.4e-22 79.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OEU11723.1 - 3.2e-17 63.3 5.8 2.2e-05 24.4 0.0 4.6 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU11723.1 - 7.5e-11 41.9 0.0 0.006 16.0 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OEU11723.1 - 1.4e-07 32.2 15.7 0.00025 21.6 0.3 3.5 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 OEU11723.1 - 5e-07 29.8 9.7 0.0078 16.0 0.1 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 OEU11723.1 - 1.3e-06 28.1 0.1 0.035 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU11723.1 - 2.2e-06 27.7 0.0 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 OEU11723.1 - 4e-06 26.8 14.6 4e-06 26.8 14.6 2.9 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 OEU11723.1 - 1.6e-05 25.2 0.2 0.048 13.9 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.6 OEU11723.1 - 2.4e-05 23.2 7.8 0.0063 15.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 OEU11723.1 - 2.5e-05 24.3 0.4 0.026 14.6 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.12 OEU11723.1 - 5e-05 23.3 0.7 0.062 13.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 OEU11723.1 - 0.00018 21.8 0.0 0.072 13.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 OEU11723.1 - 0.00037 20.3 2.4 0.055 13.2 0.1 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OEU11723.1 - 0.00048 20.5 0.3 0.51 10.7 0.0 3.2 3 0 0 3 3 3 1 RNA helicase ATP-synt_ab PF00006.25 OEU11723.1 - 0.0011 18.7 0.1 0.15 11.7 0.0 2.4 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 OEU11723.1 - 0.0012 19.3 2.1 0.15 12.5 0.5 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OEU11723.1 - 0.0013 19.3 1.1 0.07 13.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 OEU11723.1 - 0.0019 18.4 0.1 0.52 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OEU11723.1 - 0.002 18.5 0.2 0.3 11.5 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 OEU11723.1 - 0.004 17.2 0.0 3.3 7.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 OEU11723.1 - 0.0047 16.4 0.1 0.19 11.2 0.1 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family cobW PF02492.19 OEU11723.1 - 0.0061 16.2 0.7 0.31 10.6 0.2 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OEU11723.1 - 0.013 15.8 0.2 1.2 9.4 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OEU11723.1 - 0.014 15.3 3.4 1.2 9.0 0.4 3.5 2 1 0 2 2 2 0 NTPase dNK PF01712.19 OEU11723.1 - 0.027 14.3 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 OEU11723.1 - 0.034 13.9 8.9 0.17 11.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_27 PF13514.6 OEU11723.1 - 0.051 13.2 3.1 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 OEU11723.1 - 0.061 13.3 2.6 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 OEU11723.1 - 0.066 10.7 0.1 0.066 10.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 OEU11723.1 - 0.07 12.9 0.5 0.88 9.3 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OEU11723.1 - 0.089 12.3 0.3 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 OEU11723.1 - 0.094 12.3 1.5 1 9.0 0.2 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 OEU11723.1 - 0.15 12.3 1.0 6.2 7.1 0.1 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.14 OEU11723.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Vfa1 PF08432.10 OEU11723.1 - 0.47 10.8 7.7 0.94 9.8 7.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_5 PF07728.14 OEU11723.1 - 1 9.3 5.4 2.9 7.9 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 OEU11723.1 - 1.1 9.3 7.7 4.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain FliD_N PF02465.18 OEU11723.1 - 3.1 8.6 7.8 7.9 7.2 7.8 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Dynamin_N PF00350.23 OEU11723.1 - 3.3 7.7 8.3 22 5.1 0.0 3.6 3 1 0 3 3 2 0 Dynamin family TraV PF09676.10 OEU11723.1 - 3.7 8.5 5.5 8.7 7.3 5.5 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Asp-B-Hydro_N PF05279.11 OEU11724.1 - 9 6.3 16.7 12 5.9 16.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TPR_12 PF13424.6 OEU11725.1 - 4.4e-30 103.8 0.6 2.8e-10 40.4 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OEU11725.1 - 4.9e-19 67.6 0.2 0.0008 19.2 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU11725.1 - 5.8e-19 66.6 0.1 0.011 15.7 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU11725.1 - 2.5e-17 61.6 4.6 0.025 14.8 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11725.1 - 2e-15 55.9 0.2 0.018 14.8 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 OEU11725.1 - 3.2e-07 30.5 0.3 0.055 14.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU11725.1 - 4.6e-07 29.4 3.4 2.6 8.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU11725.1 - 9.9e-06 24.9 0.1 0.0005 19.5 0.2 3.6 4 0 0 4 4 4 1 SHNi-TPR TPR_14 PF13428.6 OEU11725.1 - 6.4e-05 23.5 0.1 56 4.9 0.0 5.6 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU11725.1 - 0.0001 22.7 0.5 3.6 8.2 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU11725.1 - 0.00013 22.5 0.0 13 6.5 0.0 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 OEU11725.1 - 0.0086 16.1 5.3 9.5 6.4 0.0 4.6 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OEU11725.1 - 0.0095 15.6 3.2 5.1 6.9 0.2 4.8 5 0 0 5 5 5 1 TPR repeat PPR PF01535.20 OEU11725.1 - 0.022 15.0 0.1 32 5.1 0.0 4.3 4 0 0 4 4 4 0 PPR repeat ANAPC5 PF12862.7 OEU11725.1 - 0.023 14.8 3.0 3.3 7.8 0.0 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 COPI_C PF06957.11 OEU11725.1 - 0.043 12.6 0.0 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus CLP1_P PF16575.5 OEU11726.1 - 2e-38 132.1 0.0 3e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OEU11726.1 - 2.2e-21 76.4 0.0 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 OEU11726.1 - 4.7e-16 58.8 0.0 8.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_24 PF13479.6 OEU11726.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OEU11726.1 - 0.0016 18.5 0.0 0.006 16.6 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 OEU11726.1 - 0.0039 17.6 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OEU11726.1 - 0.011 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 OEU11726.1 - 0.035 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 OEU11726.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OEU11726.1 - 0.044 13.9 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OEU11726.1 - 0.094 13.2 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 OEU11726.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OEU11726.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU11726.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 OEU11728.1 - 4.6e-82 275.6 0.0 6e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Silic_transp PF03842.13 OEU11729.1 - 1.9e-196 653.3 9.7 2.3e-196 653.1 9.7 1.0 1 0 0 1 1 1 1 Silicon transporter FAM184 PF15665.5 OEU11729.1 - 0.08 12.7 0.7 0.12 12.1 0.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B 2OG-FeII_Oxy_3 PF13640.6 OEU11730.1 - 0.0044 17.9 0.0 0.0054 17.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAM33 PF02330.16 OEU11732.1 - 0.44 10.5 4.7 0.33 10.9 3.1 1.5 2 0 0 2 2 2 0 Mitochondrial glycoprotein Ndc1_Nup PF09531.10 OEU11732.1 - 0.44 9.2 9.2 0.51 9.0 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_21 PF05050.12 OEU11733.1 - 1.7e-13 50.9 0.0 3.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-RING_2 PF13639.6 OEU11737.1 - 3.6e-06 27.2 8.2 7.9e-06 26.1 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OEU11737.1 - 2.9e-05 23.9 8.5 5.3e-05 23.1 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OEU11737.1 - 0.00042 20.6 5.3 0.0011 19.2 5.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OEU11737.1 - 0.0006 19.5 4.4 0.0014 18.4 4.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU11737.1 - 0.002 17.9 9.4 0.005 16.7 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU11737.1 - 0.0032 17.5 3.3 0.0034 17.4 1.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU11737.1 - 0.091 12.8 3.1 0.2 11.7 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DEC-1_N PF04625.13 OEU11737.1 - 0.11 11.5 1.3 0.15 11.0 1.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-C3HC4_2 PF13923.6 OEU11737.1 - 0.11 12.3 11.5 4.8 7.1 11.1 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU11737.1 - 0.7 9.8 6.8 9.2 6.2 6.8 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 OEU11737.1 - 1 9.4 6.3 4.8 7.3 6.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 OEU11737.1 - 1.3 9.0 7.3 14 5.7 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OEU11737.1 - 1.6 8.7 9.4 9.6 6.2 8.5 2.2 1 1 1 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 OEU11737.1 - 3.7 7.2 7.8 3 7.6 4.9 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OEU11737.1 - 4.9 7.6 7.6 1.8 9.0 2.3 2.3 1 1 1 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 OEU11737.1 - 6 7.1 9.2 73 3.6 9.4 2.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OEU11737.1 - 9.9 6.1 10.0 62 3.6 10.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 OEU11738.1 - 0.02 14.9 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat YscJ_FliF_C PF08345.11 OEU11740.1 - 3.2 8.1 13.0 0.26 11.6 3.4 2.2 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal DUF1673 PF07895.11 OEU11742.1 - 0.54 9.9 4.0 1.9 8.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF3488 PF11992.8 OEU11742.1 - 0.6 9.0 5.5 0.064 12.2 0.3 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3488) PDZ PF00595.24 OEU11743.1 - 0.0026 18.1 0.4 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain DUF1398 PF07166.11 OEU11743.1 - 0.015 15.3 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) Methyltrans_Mon PF14314.6 OEU11743.1 - 0.061 11.4 0.2 0.1 10.6 0.1 1.3 1 1 0 1 1 1 0 Virus-capping methyltransferase SR-25 PF10500.9 OEU11744.1 - 0.16 11.5 19.5 0.84 9.2 12.1 2.7 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nepo_coat PF03391.15 OEU11744.1 - 0.23 10.9 2.4 6.4 6.2 0.2 2.4 2 0 0 2 2 2 0 Nepovirus coat protein, central domain DUF3439 PF11921.8 OEU11744.1 - 6 6.9 13.7 3.5 7.6 1.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) DUF3827 PF12877.7 OEU11745.1 - 0.0043 15.5 0.9 0.0064 14.9 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) ATP11 PF06644.11 OEU11745.1 - 0.014 15.2 1.1 0.023 14.5 1.1 1.3 1 0 0 1 1 1 0 ATP11 protein DUF1779 PF08680.10 OEU11745.1 - 0.021 15.0 1.2 0.11 12.6 0.6 2.2 1 1 0 1 1 1 0 TATA-box binding PTPRCAP PF15713.5 OEU11746.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.4 2 1 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TBCA PF02970.16 OEU11747.1 - 0.026 14.8 0.2 0.76 10.1 0.1 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A Cadherin_C_2 PF16492.5 OEU11748.1 - 0.021 15.5 0.9 11 6.8 0.1 2.8 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal CD20 PF04103.15 OEU11748.1 - 0.11 12.6 0.1 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 CD20-like family SIT PF15330.6 OEU11748.1 - 0.14 12.6 0.5 0.64 10.5 0.5 2.1 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 OEU11748.1 - 0.19 12.6 1.5 2.4 9.1 1.3 2.9 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 OEU11748.1 - 0.37 10.6 0.0 0.37 10.6 0.0 2.2 2 1 1 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Macoilin PF09726.9 OEU11748.1 - 0.85 8.1 7.6 1.3 7.5 7.6 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 OEU11748.1 - 1.6 7.4 7.3 2.7 6.7 7.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4834 PF16118.5 OEU11748.1 - 6.6 7.8 14.6 0.22 12.5 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) F-protein PF00469.20 OEU11748.1 - 7.9 6.0 7.2 14 5.2 7.2 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SART-1 PF03343.13 OEU11750.1 - 0.0065 15.1 0.3 0.0072 14.9 0.3 1.1 1 0 0 1 1 1 1 SART-1 family BTB_2 PF02214.22 OEU11751.1 - 1.9e-07 31.3 0.5 7.9e-07 29.3 0.0 2.4 2 1 0 2 2 2 1 BTB/POZ domain LRRC37AB_C PF14914.6 OEU11752.1 - 0.067 13.1 0.3 0.083 12.8 0.3 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain PI3K_1B_p101 PF10486.9 OEU11752.1 - 0.073 10.8 0.3 0.076 10.8 0.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4611 PF15387.6 OEU11752.1 - 1.2 9.4 7.4 1.8 8.8 7.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 OEU11752.1 - 2.8 7.6 5.0 2.9 7.5 5.0 1.3 1 1 0 1 1 1 0 FAM176 family SlyX PF04102.12 OEU11753.1 - 0.00067 20.2 1.2 0.00067 20.2 1.2 3.6 3 0 0 3 3 3 1 SlyX Spt20 PF12090.8 OEU11753.1 - 0.00079 19.1 23.1 0.00079 19.1 23.1 4.2 3 1 1 4 4 4 2 Spt20 family Androgen_recep PF02166.16 OEU11753.1 - 4.2 6.1 38.3 0.47 9.2 8.5 2.7 2 0 0 2 2 2 0 Androgen receptor FTZ PF03867.14 OEU11753.1 - 8.2 5.9 21.3 11 5.5 6.8 2.7 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region ABC1 PF03109.16 OEU11754.1 - 8.2e-24 84.1 0.0 1.6e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU11754.1 - 1.3e-06 28.5 0.2 5e-06 26.6 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU11754.1 - 0.0031 16.9 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Leu_Phe_trans PF03588.14 OEU11755.1 - 0.076 12.5 0.1 0.076 12.5 0.1 1.5 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase Fasciclin PF02469.22 OEU11757.1 - 2.4e-12 47.2 0.0 8.5e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Fasciclin domain LRR_6 PF13516.6 OEU11758.1 - 4.7e-10 38.7 7.6 0.029 14.4 0.0 6.3 5 0 0 5 5 5 4 Leucine Rich repeat TFIIA PF03153.13 OEU11758.1 - 1.8e-05 25.0 20.5 1.8e-05 25.0 20.5 3.3 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit LRR_8 PF13855.6 OEU11758.1 - 0.0025 17.6 10.0 0.47 10.2 0.1 5.1 4 1 0 4 4 4 2 Leucine rich repeat SUIM_assoc PF16619.5 OEU11758.1 - 1.5 8.9 37.2 1.4 9.1 4.6 4.6 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 LRR_1 PF00560.33 OEU11758.1 - 3 8.7 23.8 95 4.2 0.0 8.7 9 0 0 9 9 9 0 Leucine Rich Repeat XRN_M PF17846.1 OEU11758.1 - 3.6 6.4 15.1 0.05 12.6 4.6 2.7 3 0 0 3 3 3 0 Xrn1 helical domain SET PF00856.28 OEU11759.1 - 1.4e-07 32.0 0.3 1.1e-06 29.1 0.3 2.2 1 1 0 1 1 1 1 SET domain Gly_rich PF12810.7 OEU11759.1 - 0.0025 17.8 5.9 0.0025 17.8 5.9 1.9 2 0 0 2 2 2 1 Glycine rich protein HECT PF00632.25 OEU11760.1 - 5.1e-82 275.8 0.0 6.2e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MtN3_slv PF03083.16 OEU11762.1 - 2.7e-25 88.2 14.0 1.3e-13 50.7 3.0 3.7 4 0 0 4 4 4 3 Sugar efflux transporter for intercellular exchange YMF19 PF02326.15 OEU11762.1 - 0.91 10.3 4.4 7.7 7.4 0.1 3.0 3 0 0 3 3 3 0 Plant ATP synthase F0 TRAM_LAG1_CLN8 PF03798.16 OEU11763.1 - 7.2e-17 61.8 18.7 7.2e-17 61.8 18.7 2.6 1 1 0 2 2 2 1 TLC domain DUF1385 PF07136.11 OEU11763.1 - 0.068 12.4 4.7 0.31 10.3 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) TMEM154 PF15102.6 OEU11763.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.5 1 1 1 2 2 2 0 TMEM154 protein family cobW PF02492.19 OEU11764.1 - 3.9e-32 111.2 1.7 7.6e-32 110.3 1.7 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU11764.1 - 7.4e-13 48.2 0.0 2.1e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Zip PF02535.22 OEU11764.1 - 0.064 12.5 5.5 0.11 11.7 5.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter MobB PF03205.14 OEU11764.1 - 0.15 11.9 1.0 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SPX PF03105.19 OEU11764.1 - 0.47 10.3 6.1 0.084 12.8 1.1 2.0 2 0 0 2 2 2 0 SPX domain Dynamin_M PF01031.20 OEU11766.1 - 0.0078 15.5 0.8 0.015 14.5 0.8 1.4 1 0 0 1 1 1 1 Dynamin central region DUF1139 PF06599.11 OEU11766.1 - 3.9 6.8 10.7 0.089 12.2 1.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1139) ABC2_membrane_3 PF12698.7 OEU11766.1 - 6.1 5.8 8.4 9.5 5.2 8.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein UDG PF03167.19 OEU11767.1 - 4.5e-17 62.5 0.0 6.1e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LolA PF03548.15 OEU11768.1 - 0.0033 17.1 0.0 2.9 7.6 0.0 3.2 3 1 1 4 4 4 2 Outer membrane lipoprotein carrier protein LolA AAA_33 PF13671.6 OEU11770.1 - 0.0074 16.4 0.6 0.028 14.6 0.0 2.2 2 1 1 3 3 3 1 AAA domain Choline_transpo PF04515.12 OEU11771.1 - 3.4e-66 223.7 16.2 3.4e-66 223.7 16.2 2.0 1 1 1 2 2 2 1 Plasma-membrane choline transporter FAM176 PF14851.6 OEU11771.1 - 0.1 12.2 0.1 4.5 6.9 0.0 2.8 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 OEU11771.1 - 0.2 12.1 1.2 1.9 8.9 0.1 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain GTA_holin_3TM PF11351.8 OEU11771.1 - 1.1 9.8 2.8 3.8 8.1 2.8 1.9 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Sulf_transp PF04143.14 OEU11772.1 - 1.4e-11 44.5 18.6 4e-08 33.2 5.1 3.1 2 1 1 3 3 3 2 Sulphur transport MASE2 PF05230.11 OEU11772.1 - 0.061 13.4 0.4 6.2 7.0 0.0 3.0 2 1 0 2 2 2 0 MASE2 domain BRCT PF00533.26 OEU11773.1 - 5.8e-05 23.4 2.8 0.00057 20.2 0.0 3.6 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.18 OEU11773.1 - 8.1e-05 23.4 6.7 0.29 12.0 0.1 3.2 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DnaJ PF00226.31 OEU11773.1 - 0.00076 19.6 0.1 0.0031 17.6 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain DUF5538 PF17692.1 OEU11773.1 - 7.2 6.7 10.3 5.7 7.0 7.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5538) HIRAN PF08797.11 OEU11774.1 - 7.5e-07 29.0 0.1 2.6e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 HIRAN domain WBP-1 PF11669.8 OEU11775.1 - 0.077 13.6 0.0 0.077 13.6 0.0 3.5 4 1 1 5 5 5 0 WW domain-binding protein 1 PanZ PF12568.8 OEU11775.1 - 0.23 11.2 3.8 1.3 8.7 1.3 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ TraG_N PF07916.11 OEU11775.1 - 8.9 5.0 15.6 16 4.2 12.0 2.2 1 1 1 2 2 2 0 TraG-like protein, N-terminal region FMN_red PF03358.15 OEU11777.1 - 1.1e-36 125.9 0.0 1.5e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OEU11777.1 - 6.8e-08 32.5 0.0 9.7e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.16 OEU11778.1 - 1.1e-27 97.0 19.5 1.1e-27 97.0 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_14 PF13428.6 OEU11780.1 - 1e-12 47.7 5.3 0.0002 21.9 0.2 7.6 5 2 4 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU11780.1 - 5.2e-08 33.3 0.3 0.00046 20.7 0.1 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU11780.1 - 1.4e-07 31.1 0.9 0.23 11.7 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU11780.1 - 0.00014 22.4 1.3 0.066 13.9 0.6 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU11780.1 - 0.00044 20.2 4.9 0.54 10.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU11780.1 - 0.0017 18.1 0.1 1.1 9.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU11780.1 - 0.0032 17.7 0.5 66 4.2 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU11780.1 - 0.025 15.2 0.6 17 6.3 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PH_4 PF15404.6 OEU11780.1 - 0.096 12.5 2.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Sel1 PF08238.12 OEU11780.1 - 0.48 11.2 2.2 1.5 9.6 0.1 3.1 4 0 0 4 4 4 0 Sel1 repeat COMM_domain PF07258.14 OEU11781.1 - 0.098 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 COMM domain PDZ_2 PF13180.6 OEU11782.1 - 0.0035 17.6 0.0 0.0089 16.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU11782.1 - 0.027 14.8 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 OEU11782.1 - 0.031 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PLDc_2 PF13091.6 OEU11783.1 - 4.9e-08 32.9 10.0 0.00059 19.7 1.3 4.4 3 1 1 4 4 4 3 PLD-like domain TruB_N PF01509.18 OEU11783.1 - 0.028 14.8 0.2 0.49 10.7 0.1 2.6 2 0 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) PLDc PF00614.22 OEU11783.1 - 0.047 13.9 4.8 0.98 9.7 0.0 3.5 3 0 0 3 3 3 0 Phospholipase D Active site motif Ank_2 PF12796.7 OEU11784.1 - 2e-09 37.9 0.1 7.3e-05 23.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU11784.1 - 6.2e-07 29.2 0.0 0.75 10.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OEU11784.1 - 1.4e-05 25.5 0.1 0.9 10.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU11784.1 - 0.0002 21.5 0.0 0.082 13.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DHHW PF14286.6 OEU11784.1 - 0.037 13.4 0.2 0.046 13.0 0.2 1.1 1 0 0 1 1 1 0 DHHW protein Ank PF00023.30 OEU11784.1 - 0.15 12.6 0.0 31 5.3 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeat zf-MYND PF01753.18 OEU11785.1 - 3.5e-09 36.6 10.2 3.5e-09 36.6 10.2 2.6 2 1 0 2 2 2 1 MYND finger SPATA48 PF15073.6 OEU11785.1 - 0.021 15.1 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 C1_2 PF03107.16 OEU11785.1 - 1.2 9.5 17.0 1.4 9.3 4.5 3.5 3 0 0 3 3 3 0 C1 domain tRNA-synt_2d PF01409.20 OEU11786.1 - 3.3e-53 180.7 0.1 2.1e-30 106.0 0.0 2.2 1 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OEU11786.1 - 7.4e-21 74.4 0.0 1.6e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 OEU11786.1 - 0.13 11.3 0.1 14 4.6 0.0 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Mucin PF01456.17 OEU11787.1 - 0.018 15.1 16.6 0.32 11.0 6.1 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein 2Fe-2S_thioredx PF01257.19 OEU11787.1 - 0.23 11.3 1.8 0.37 10.6 0.9 1.8 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF3439 PF11921.8 OEU11787.1 - 0.56 10.2 12.3 0.28 11.2 4.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Lipase_GDSL_2 PF13472.6 OEU11790.1 - 9.5e-11 42.4 0.0 1.6e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU11790.1 - 3.4e-10 40.2 0.0 4.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase IPT PF01745.16 OEU11790.1 - 0.0056 16.1 0.0 0.0073 15.7 0.0 1.1 1 0 0 1 1 1 1 Isopentenyl transferase Stork_head PF10264.9 OEU11793.1 - 0.058 13.6 0.0 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain UCR_Fe-S_N PF10399.9 OEU11793.1 - 0.068 12.5 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Frag1 PF10277.9 OEU11795.1 - 1.1e-09 38.2 13.2 2e-09 37.3 13.2 1.4 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF981 PF06168.11 OEU11795.1 - 0.0008 19.4 6.3 0.0008 19.4 6.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF981) SHR3_chaperone PF08229.11 OEU11795.1 - 0.08 11.9 6.1 0.21 10.5 3.3 2.5 2 1 0 2 2 2 0 ER membrane protein SH3 DUF4149 PF13664.6 OEU11795.1 - 2.9 8.3 9.1 0.4 11.0 2.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Clavanin PF05452.11 OEU11795.1 - 8 6.7 6.3 7.1 6.9 0.8 3.1 2 1 2 4 4 4 0 Clavanin zf-RING_2 PF13639.6 OEU11797.1 - 1e-08 35.4 5.1 1.8e-08 34.6 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU11797.1 - 1.8e-05 24.4 5.7 3.6e-05 23.4 5.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 OEU11797.1 - 3.3e-05 24.0 2.6 6.4e-05 23.1 2.6 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OEU11797.1 - 0.0026 17.7 0.4 0.0074 16.3 0.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OEU11797.1 - 0.0039 17.4 3.2 0.0039 17.4 3.2 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU11797.1 - 0.0058 16.5 5.3 0.014 15.2 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 OEU11797.1 - 0.011 15.8 0.7 0.035 14.2 0.7 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 OEU11797.1 - 0.062 13.2 3.2 0.31 11.0 0.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 OEU11797.1 - 0.074 12.7 2.5 0.17 11.5 2.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OEU11797.1 - 0.093 12.8 2.3 0.41 10.7 2.4 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP_var PF17807.1 OEU11797.1 - 0.11 12.2 0.5 3.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Variant UBP zinc finger MSP1a PF11670.8 OEU11797.1 - 0.19 11.0 3.0 0.44 9.8 0.4 2.1 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) zf-C3HC4_3 PF13920.6 OEU11797.1 - 0.19 11.6 6.8 0.7 9.8 6.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU11797.1 - 0.29 11.1 5.6 0.81 9.7 5.6 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 OEU11797.1 - 0.3 10.9 2.0 0.48 10.3 0.7 2.0 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 OEU11797.1 - 0.64 10.0 6.2 1.2 9.0 6.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 OEU11797.1 - 1.5 8.7 10.9 13 5.7 10.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OEU11797.1 - 3.4 7.8 7.1 0.52 10.4 1.0 2.2 2 0 0 2 2 2 0 Zinc-finger SUIM_assoc PF16619.5 OEU11798.1 - 0.0061 16.6 10.3 1.6 8.9 6.8 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 PI-PLC-X PF00388.19 OEU11798.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DnaJ PF00226.31 OEU11799.1 - 4e-07 30.1 0.1 5.6e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.18 OEU11800.1 - 8.3e-08 32.2 15.2 8.3e-08 32.2 15.2 2.4 2 0 0 2 2 2 1 MYND finger CxC4 PF18717.1 OEU11800.1 - 0.19 11.6 5.5 0.36 10.7 5.5 1.4 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases SIR2 PF02146.17 OEU11801.1 - 3.3e-45 154.2 0.0 4.1e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Cas6b_C PF17262.2 OEU11801.1 - 0.053 13.6 0.6 0.25 11.4 0.1 2.0 1 1 1 2 2 2 0 Cas6b C-terminal domain SURNod19 PF07712.12 OEU11802.1 - 2e-09 36.7 0.5 2e-09 36.7 0.5 2.9 3 0 0 3 3 3 1 Stress up-regulated Nod 19 NICE-1 PF15845.5 OEU11802.1 - 5.6 7.8 12.4 28 5.6 8.0 2.4 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family NopRA1 PF16201.5 OEU11803.1 - 0.033 13.8 0.4 0.36 10.4 0.0 2.6 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 HA PF03457.14 OEU11803.1 - 0.2 12.0 1.8 0.51 10.7 1.8 1.6 1 0 0 1 1 1 0 Helicase associated domain FAM176 PF14851.6 OEU11803.1 - 6.6 6.4 28.2 0.6 9.8 6.2 4.4 4 0 0 4 4 4 0 FAM176 family zf-CCHC_5 PF14787.6 OEU11804.1 - 0.0012 18.5 1.0 0.0037 16.9 1.0 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OEU11804.1 - 0.089 12.9 1.2 0.25 11.5 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle PD40 PF07676.12 OEU11805.1 - 0.00015 21.6 1.1 0.14 12.1 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 OEU11805.1 - 0.00015 22.5 6.1 0.00016 22.4 0.1 3.5 3 1 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OEU11805.1 - 0.0088 15.0 0.4 14 4.5 0.0 3.4 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NUDIX PF00293.28 OEU11806.1 - 1.9e-11 44.1 0.0 4e-11 43.1 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain DUF726 PF05277.12 OEU11807.1 - 3.9e-65 220.1 3.7 6e-27 94.5 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF726) SIS_2 PF13580.6 OEU11807.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 SIS domain RRM_1 PF00076.22 OEU11810.1 - 3.6e-10 39.5 0.1 0.0037 17.1 0.0 4.9 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 OEU11810.1 - 9.5e-10 38.1 14.8 0.00035 20.4 0.1 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU11810.1 - 1.2e-09 37.9 31.0 0.00014 21.8 4.6 3.9 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 OEU11810.1 - 3.6e-06 27.6 16.6 0.035 14.8 1.0 4.1 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 OEU11810.1 - 8.5e-05 22.7 11.1 0.32 11.2 0.7 3.5 3 0 0 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 OEU11810.1 - 0.00015 21.5 21.5 0.013 15.2 2.0 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OEU11810.1 - 0.0023 18.3 18.1 0.19 12.3 1.9 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger HA PF03457.14 OEU11811.1 - 4.9e-41 138.9 6.7 1.3e-16 60.6 1.0 3.0 3 0 0 3 3 3 3 Helicase associated domain DUF3836 PF12930.7 OEU11811.1 - 0.048 13.4 2.1 7.5 6.3 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF3836) Auxin_canalis PF05703.11 OEU11811.1 - 0.57 10.1 1.2 17 5.2 0.1 2.0 2 0 0 2 2 2 0 Auxin canalisation Helicase_C PF00271.31 OEU11812.1 - 2e-16 60.3 0.1 8.2e-16 58.3 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain UvrB PF12344.8 OEU11812.1 - 9.8e-11 41.3 2.9 9.9e-11 41.3 1.1 2.0 2 0 0 2 2 2 1 Ultra-violet resistance protein B ResIII PF04851.15 OEU11812.1 - 1.2e-09 38.4 0.7 2.3e-08 34.2 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OEU11812.1 - 8.7e-05 22.3 0.0 0.0017 18.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OEU11812.1 - 0.00012 22.4 0.1 0.74 10.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 OEU11812.1 - 0.0018 18.1 0.0 0.038 13.8 0.0 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OEU11812.1 - 0.0032 17.7 0.0 0.016 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Kinesin PF00225.23 OEU11812.1 - 0.0062 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain AAA_7 PF12775.7 OEU11812.1 - 0.0081 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 OEU11812.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1090 PF06476.12 OEU11812.1 - 0.023 14.8 1.8 0.089 12.9 1.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF5591 PF17884.1 OEU11812.1 - 0.024 14.5 0.1 0.065 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) Miga PF10265.9 OEU11812.1 - 0.084 11.8 0.7 0.13 11.2 0.7 1.2 1 0 0 1 1 1 0 Mitoguardin AAA_15 PF13175.6 OEU11812.1 - 0.091 12.4 8.8 3.5 7.2 8.8 2.3 1 1 0 1 1 1 0 AAA ATPase domain DUF1351 PF07083.11 OEU11812.1 - 0.21 11.3 4.4 3.5 7.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) GIY-YIG PF01541.24 OEU11813.1 - 2.8e-11 43.5 0.0 4.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain UvrC_HhH_N PF08459.11 OEU11814.1 - 2.9e-43 147.4 0.0 4e-35 121.0 0.0 2.3 2 1 0 2 2 2 2 UvrC Helix-hairpin-helix N-terminal DUF1180 PF06679.12 OEU11815.1 - 0.027 14.9 1.6 0.034 14.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SSP160 PF06933.11 OEU11815.1 - 5.5 5.1 16.9 6.7 4.8 16.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_9_N PF15420.6 OEU11816.1 - 0.28 11.1 4.6 0.34 10.9 4.6 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF3357 PF11837.8 OEU11816.1 - 1.7 9.2 4.3 2.3 8.7 4.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) UCR_hinge PF02320.16 OEU11818.1 - 5.9e-14 52.0 0.9 6.5e-14 51.9 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4304 PF14137.6 OEU11819.1 - 0.061 13.5 1.1 1.1 9.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4304) Auxin_BP PF02041.16 OEU11819.1 - 0.14 11.8 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Auxin binding protein PALP PF00291.25 OEU11820.1 - 2e-59 201.4 0.2 2.4e-59 201.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBF_like PF13593.6 OEU11821.1 - 1.4e-60 205.3 22.0 1.6e-60 205.1 22.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 OEU11821.1 - 7.3e-10 38.8 15.4 7.3e-10 38.8 15.4 1.9 1 1 0 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 OEU11821.1 - 0.0028 16.1 1.3 0.0028 16.1 1.3 2.0 1 1 2 3 3 3 1 Membrane transport protein FPP PF05911.11 OEU11823.1 - 0.00092 17.5 5.6 0.00092 17.5 5.6 1.4 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Spc24 PF08286.11 OEU11823.1 - 5.5 7.3 8.2 1.6 9.0 4.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF3915 PF13054.6 OEU11826.1 - 0.81 9.7 4.9 1.7 8.6 1.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Dirigent PF03018.14 OEU11828.1 - 0.0031 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Dirigent-like protein Polysacc_deac_1 PF01522.21 OEU11829.1 - 3.8e-15 55.9 0.3 8.4e-15 54.8 0.3 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase GRP PF07172.11 OEU11829.1 - 1.7 9.4 7.8 3.6 8.3 4.6 2.9 2 0 0 2 2 2 0 Glycine rich protein family Antistasin PF02822.14 OEU11830.1 - 0.044 14.4 5.9 32 5.3 1.3 4.2 3 0 0 3 3 3 0 Antistasin family DUF4507 PF14964.6 OEU11831.1 - 0.029 13.3 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) HemY_N PF07219.13 OEU11831.1 - 0.061 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus E1_dh PF00676.20 OEU11832.1 - 9.4e-11 41.2 0.3 3e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component Transketolase_C PF02780.20 OEU11832.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain BsuBI_PstI_RE PF06616.11 OEU11833.1 - 0.026 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain DUF1772 PF08592.11 OEU11833.1 - 0.093 13.0 0.5 8.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) zf-MYND PF01753.18 OEU11835.1 - 1.2e-07 31.7 14.0 1.2e-07 31.7 14.0 3.3 2 1 0 2 2 2 1 MYND finger Sel1 PF08238.12 OEU11835.1 - 1.5e-06 28.7 0.1 0.28 11.9 0.0 4.2 3 1 1 4 4 4 2 Sel1 repeat TPR_17 PF13431.6 OEU11835.1 - 0.0094 16.3 1.3 0.12 12.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU11835.1 - 0.044 13.5 0.4 14 5.5 0.0 3.0 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 OEU11835.1 - 0.45 10.4 3.1 20 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTB PF00651.31 OEU11836.1 - 4.5e-05 23.6 0.0 0.00012 22.3 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_S41 PF03572.18 OEU11837.1 - 4.3e-36 124.0 0.1 1.7e-34 118.8 0.1 3.0 1 1 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 OEU11837.1 - 8e-10 38.4 0.0 1.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU11837.1 - 7.4e-05 23.0 0.0 0.00028 21.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU11837.1 - 0.00072 19.8 0.1 0.0029 17.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain NAD_binding_8 PF13450.6 OEU11838.1 - 0.00012 22.2 0.0 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU11838.1 - 0.00049 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 OEU11838.1 - 0.0037 16.5 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OEU11838.1 - 0.019 14.2 0.0 0.052 12.8 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sulfotransfer_4 PF17784.1 OEU11838.1 - 0.12 12.2 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Sulfotransferase domain NAD_binding_9 PF13454.6 OEU11838.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 OEU11840.1 - 1.5e-77 261.4 16.6 1.8e-77 261.1 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU11840.1 - 3.9e-10 39.2 22.8 3.9e-10 39.2 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 OEU11840.1 - 0.0009 19.9 5.8 0.17 12.5 3.3 3.2 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 OEU11840.1 - 0.0024 18.8 7.5 0.035 15.1 1.7 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) LAB_N PF07578.11 OEU11840.1 - 0.0051 16.9 0.5 0.022 14.9 0.5 2.1 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain DUF3112 PF11309.8 OEU11840.1 - 0.01 15.3 0.7 0.01 15.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF2304 PF10066.9 OEU11840.1 - 0.057 13.6 0.8 0.057 13.6 0.8 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2589 PF11655.8 OEU11840.1 - 0.068 13.5 0.1 0.068 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) zf-H3C2 PF16721.5 OEU11841.1 - 0.037 14.4 0.1 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding DUF1336 PF07059.12 OEU11843.1 - 1.4e-46 159.4 0.0 4.3e-46 157.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) PH PF00169.29 OEU11843.1 - 0.0032 17.9 2.4 0.62 10.6 0.0 3.1 3 0 0 3 3 3 2 PH domain DEAD PF00270.29 OEU11844.1 - 3.6e-10 39.9 0.0 4.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 OEU11844.1 - 0.05 13.2 0.1 0.054 13.1 0.1 1.0 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OEU11844.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU11844.1 - 0.16 12.2 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 OEU11845.1 - 9.8e-07 29.1 0.1 1.3e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RVT PF13966.6 OEU11846.1 - 0.0017 19.0 1.3 0.0017 19.0 1.3 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase MID_MedPIWI PF18296.1 OEU11847.1 - 2 8.1 10.7 1.9 8.2 9.7 1.4 1 1 0 1 1 1 0 MID domain of medPIWI L51_S25_CI-B8 PF05047.16 OEU11848.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1995 PF09353.10 OEU11849.1 - 2.4e-20 73.4 0.0 1.4e-19 70.9 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) MDFI PF15316.6 OEU11850.1 - 6.4 6.8 5.9 8.7 6.4 0.2 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Fungus-induced PF10917.8 OEU11851.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungus-induced protein RDD PF06271.12 OEU11852.1 - 4.1e-10 40.0 10.8 1.3e-09 38.4 10.8 1.9 1 1 0 1 1 1 1 RDD family PHO4 PF01384.20 OEU11852.1 - 0.06 12.4 0.1 0.091 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphate transporter family Crl PF07417.12 OEU11852.1 - 0.14 12.3 1.1 0.3 11.2 0.0 2.0 1 1 1 2 2 2 0 Sigma factor-binding transcriptional regulator Crl Sar8_2 PF03058.14 OEU11852.1 - 2.1 8.9 8.3 3.1 8.4 1.5 3.3 3 0 0 3 3 3 0 Sar8.2 family TMEM51 PF15345.6 OEU11852.1 - 6.2 6.6 5.9 1.3 8.8 0.8 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 PT PF04886.12 OEU11854.1 - 0.016 14.7 81.6 0.5 10.0 8.7 6.6 5 2 0 5 5 5 0 PT repeat His_Phos_1 PF00300.22 OEU11855.1 - 7.4e-31 107.4 0.0 1.4e-21 77.1 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) GlnE PF03710.15 OEU11855.1 - 0.21 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase zf-U11-48K PF05253.12 OEU11856.1 - 2 8.4 3.5 1.3e+02 2.6 0.1 3.2 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger CaMKII_AD PF08332.10 OEU11857.1 - 8.2e-32 110.1 0.2 9e-32 109.9 0.2 1.0 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 OEU11857.1 - 2e-10 41.0 0.1 2.4e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OEU11857.1 - 9.3e-08 32.4 0.0 1.1e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) MTBP_mid PF14919.6 OEU11857.1 - 0.051 12.8 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding HSF_DNA-bind PF00447.17 OEU11858.1 - 4.5e-20 72.1 1.1 5.1e-20 71.9 1.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_18 PF00704.28 OEU11859.1 - 3.1e-14 53.4 0.0 3.6e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cellulase PF00150.18 OEU11860.1 - 0.00022 20.7 1.6 0.17 11.2 0.0 3.4 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) F420_oxidored PF03807.17 OEU11861.1 - 7.1e-15 55.4 0.1 1.3e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OEU11861.1 - 0.0031 17.6 0.3 0.0075 16.3 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_hydro_4 PF02056.16 OEU11861.1 - 0.079 12.5 1.1 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Yae1_N PF09811.9 OEU11862.1 - 2.8e-21 74.9 35.0 0.001 18.8 0.9 10.3 2 1 9 11 11 11 10 Essential protein Yae1, N terminal Rick_17kDa_Anti PF05433.15 OEU11862.1 - 0.011 15.6 29.4 1.4 8.8 1.0 6.5 6 1 0 6 6 6 0 Glycine zipper 2TM domain DUF456 PF04306.13 OEU11862.1 - 7 6.9 24.8 11 6.4 0.9 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF456) DUF697 PF05128.12 OEU11862.1 - 7.3 6.3 10.2 5.5 6.7 0.2 4.0 2 1 3 5 5 5 0 Domain of unknown function (DUF697) ANTH PF07651.16 OEU11863.1 - 0.0014 17.7 1.5 0.0014 17.7 1.5 1.6 1 1 1 2 2 2 1 ANTH domain Secretin_N_2 PF07655.13 OEU11863.1 - 5.3 7.7 15.7 5.6 7.6 3.9 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF563 PF04577.14 OEU11864.1 - 2.2e-17 63.9 0.1 5.8e-17 62.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF563) MAP17 PF15807.5 OEU11864.1 - 0.021 15.1 0.1 0.021 15.1 0.1 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 OEU11864.1 - 0.13 13.3 6.1 0.57 11.2 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF702 PF05142.12 OEU11864.1 - 8 6.9 8.2 0.56 10.7 1.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF702) DUF4484 PF14831.6 OEU11865.1 - 5.2 7.1 15.1 3.8 7.5 8.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) RA PF00788.23 OEU11866.1 - 0.084 13.5 0.0 0.3 11.8 0.0 1.9 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Aa_trans PF01490.18 OEU11867.1 - 3.3e-48 164.4 23.3 4.3e-48 164.0 23.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec62 PF03839.16 OEU11867.1 - 0.023 14.2 0.7 0.058 12.9 0.7 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DUF383 PF04063.14 OEU11868.1 - 0.0052 16.5 0.4 0.01 15.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) Arm PF00514.23 OEU11868.1 - 0.021 14.9 0.2 0.29 11.2 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Epsilon_antitox PF08998.11 OEU11868.1 - 0.029 14.6 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Drf_GBD PF06371.13 OEU11868.1 - 0.062 12.9 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Herpes_LMP2 PF07415.11 OEU11868.1 - 0.15 10.9 0.3 0.3 9.8 0.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4264 PF14084.6 OEU11868.1 - 0.15 11.7 0.4 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) EMC3_TMCO1 PF01956.16 OEU11869.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CPSF100_C PF13299.6 OEU11869.1 - 0.6 10.3 8.5 0.85 9.8 1.2 2.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3987 PF13148.6 OEU11869.1 - 1.3 8.0 6.0 2.7 6.9 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.10 OEU11869.1 - 2 8.5 5.9 0.39 10.8 0.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CCSAP PF15748.5 OEU11869.1 - 5.8 7.0 14.8 9.5 6.3 1.7 2.6 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Dus PF01207.17 OEU11872.1 - 8e-31 107.3 0.0 1.4e-29 103.2 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF3767 PF12597.8 OEU11873.1 - 1.3e-05 24.9 0.1 1.5e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Macoilin PF09726.9 OEU11875.1 - 0.52 8.8 14.6 0.016 13.8 7.8 1.7 2 0 0 2 2 2 0 Macoilin family Lactamase_B_3 PF13483.6 OEU11876.1 - 0.0044 16.9 1.0 0.18 11.7 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TFX_C PF14601.6 OEU11876.1 - 0.095 12.7 0.6 1.9 8.5 0.3 2.6 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term HTH_Tnp_Tc3_2 PF01498.18 OEU11876.1 - 4.9 7.5 10.1 0.16 12.3 0.6 3.1 3 0 0 3 3 3 0 Transposase FKBP_C PF00254.28 OEU11877.1 - 2e-23 82.5 0.0 2.2e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Chloroa_b-bind PF00504.21 OEU11878.1 - 1.5e-36 126.3 0.0 2.5e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ETRAMP PF09716.10 OEU11879.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SNARE PF05739.19 OEU11879.1 - 0.22 11.5 0.8 0.4 10.7 0.8 1.4 1 0 0 1 1 1 0 SNARE domain TspO_MBR PF03073.15 OEU11880.1 - 8.6e-14 51.8 11.7 8.6e-14 51.8 11.7 2.5 2 1 1 3 3 3 1 TspO/MBR family ORF_12_N PF18042.1 OEU11881.1 - 0.029 14.8 0.4 0.043 14.2 0.4 1.1 1 0 0 1 1 1 0 ORF 12 gene product N-terminal 3HCDH_N PF02737.18 OEU11881.1 - 0.047 13.6 2.1 0.06 13.2 2.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2072 PF09845.9 OEU11881.1 - 0.13 12.5 1.6 0.18 12.1 1.6 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein SSP160 PF06933.11 OEU11883.1 - 0.014 13.6 2.3 0.015 13.6 2.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Galactosyl_T PF01762.21 OEU11884.1 - 0.0037 17.1 0.2 0.031 14.1 0.0 2.3 2 1 1 3 3 3 1 Galactosyltransferase Fringe PF02434.16 OEU11884.1 - 0.0037 16.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Fringe-like NUT PF12881.7 OEU11885.1 - 0.22 9.9 0.9 0.25 9.7 0.9 1.0 1 0 0 1 1 1 0 NUT protein MF_alpha_N PF05436.11 OEU11885.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Kelch_5 PF13854.6 OEU11888.1 - 1.8e-08 34.2 1.1 0.034 14.1 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 OEU11888.1 - 1.7e-07 31.1 8.2 0.081 12.9 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OEU11888.1 - 0.00025 21.2 15.5 0.096 13.0 0.1 6.4 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OEU11888.1 - 0.041 13.5 2.0 3.7 7.2 0.1 4.2 4 0 0 4 4 4 0 Kelch motif Bestrophin PF01062.21 OEU11890.1 - 2.7e-24 86.1 0.1 3.2e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel VIT1 PF01988.19 OEU11890.1 - 0.061 13.2 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 VIT family zf-CCHC_5 PF14787.6 OEU11892.1 - 0.001 18.7 1.0 0.0035 17.0 1.0 1.9 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OEU11892.1 - 0.086 13.0 1.2 0.24 11.5 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Terminase_4 PF05119.12 OEU11893.1 - 0.057 13.9 0.2 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Phage terminase, small subunit HAP1_N PF04849.13 OEU11894.1 - 0.0016 17.7 19.3 0.0096 15.2 11.8 2.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region DUF4201 PF13870.6 OEU11894.1 - 0.0019 18.0 14.4 0.0025 17.6 14.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 OEU11894.1 - 0.012 15.9 17.1 0.012 15.9 17.1 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 OEU11894.1 - 0.012 15.6 6.4 0.012 15.6 6.4 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 OEU11894.1 - 0.021 14.6 10.7 0.25 11.2 2.0 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Filament PF00038.21 OEU11894.1 - 0.051 13.2 20.5 0.058 13.0 11.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein APG17 PF04108.12 OEU11894.1 - 0.11 11.5 12.1 0.17 11.0 12.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Fib_alpha PF08702.10 OEU11894.1 - 0.13 12.4 13.7 0.11 12.7 6.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 OEU11894.1 - 0.17 10.0 14.5 0.33 9.1 14.4 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA SHE3 PF17078.5 OEU11894.1 - 0.25 11.0 17.2 0.22 11.2 9.5 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 OEU11894.1 - 0.34 10.2 7.9 1.4 8.2 8.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LsmAD PF06741.13 OEU11894.1 - 0.4 11.2 10.4 0.56 10.8 2.4 2.8 1 1 2 3 3 3 0 LsmAD domain IFT57 PF10498.9 OEU11894.1 - 0.46 9.4 14.6 0.66 8.9 14.6 1.3 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YabA PF06156.13 OEU11894.1 - 0.58 10.8 16.6 0.86 10.3 4.3 2.5 1 1 2 3 3 3 0 Initiation control protein YabA GCN5L1 PF06320.13 OEU11894.1 - 1 9.6 10.1 0.36 11.0 3.1 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) EMP24_GP25L PF01105.24 OEU11894.1 - 1.1 9.1 12.6 0.095 12.6 2.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Herpes_UL6 PF01763.16 OEU11894.1 - 1.1 7.6 8.3 1.7 7.1 7.6 1.6 1 1 1 2 2 2 0 Herpesvirus UL6 like GrpE PF01025.19 OEU11894.1 - 1.3 8.6 16.0 0.41 10.3 6.4 2.2 1 1 1 2 2 2 0 GrpE ADIP PF11559.8 OEU11894.1 - 1.3 9.1 19.9 3.5 7.7 10.2 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 OEU11894.1 - 1.5 8.3 11.3 1.7 8.1 11.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.6 OEU11894.1 - 1.5 8.1 17.2 0.87 9.0 4.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Laminin_II PF06009.12 OEU11894.1 - 1.6 8.7 10.7 11 6.1 10.7 2.0 1 1 0 1 1 1 0 Laminin Domain II Golgin_A5 PF09787.9 OEU11894.1 - 1.7 8.0 20.9 3 7.2 20.9 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2968 PF11180.8 OEU11894.1 - 1.7 8.2 13.4 0.51 10.0 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CorA PF01544.18 OEU11894.1 - 1.8 7.8 7.2 2.2 7.5 7.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HlyD_2 PF12700.7 OEU11894.1 - 1.9 7.1 10.0 1.1 7.9 8.2 1.4 1 1 0 1 1 1 0 HlyD family secretion protein TPR_MLP1_2 PF07926.12 OEU11894.1 - 2 8.5 24.5 1.4e+03 -0.7 24.5 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.13 OEU11894.1 - 2.2 8.1 12.3 0.17 11.7 2.8 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region Prominin PF05478.11 OEU11894.1 - 2.3 6.1 6.2 2.8 5.8 6.2 1.2 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.8 OEU11894.1 - 3.6 6.8 17.8 7.2 5.8 16.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 OEU11894.1 - 3.8 7.9 23.0 0.26 11.6 1.8 3.5 3 1 1 4 4 3 0 TSC-22/dip/bun family ALMT PF11744.8 OEU11894.1 - 6.1 5.6 6.2 7.3 5.3 6.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 OEU11894.1 - 6.5 5.5 6.0 7.4 5.4 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4337 PF14235.6 OEU11894.1 - 6.6 6.8 11.3 5.4 7.1 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Wtap PF17098.5 OEU11894.1 - 7.2 6.5 19.5 6.7 6.6 13.6 2.6 1 1 1 2 2 2 0 WTAP/Mum2p family Phage_GPO PF05929.11 OEU11894.1 - 8.7 5.9 11.1 17 4.9 11.1 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 OEU11894.1 - 9.5 6.1 26.1 0.98 9.2 1.7 3.8 1 1 2 4 4 4 0 Septum formation initiator GST_C_3 PF14497.6 OEU11895.1 - 1.8e-07 31.2 0.5 1.1e-05 25.5 0.1 3.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU11895.1 - 2e-06 27.7 0.0 4.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU11895.1 - 5.9e-06 26.4 0.0 0.0037 17.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OEU11895.1 - 0.00077 20.0 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OEU11895.1 - 0.0094 16.2 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU11895.1 - 0.015 15.7 0.0 0.056 13.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Mucin PF01456.17 OEU11896.1 - 7.4 6.6 18.1 4.8 7.2 1.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein EF_TS PF00889.19 OEU11898.1 - 2.4e-65 220.1 0.1 2.4e-65 220.1 0.1 1.7 2 0 0 2 2 2 1 Elongation factor TS DUF3740 PF12548.8 OEU11901.1 - 0.1 13.0 4.5 0.14 12.6 4.5 1.3 1 0 0 1 1 1 0 Sulfatase protein FAM76 PF16046.5 OEU11901.1 - 1.1 8.6 9.3 1.3 8.4 9.3 1.1 1 0 0 1 1 1 0 FAM76 protein Glyco_tranf_2_4 PF13704.6 OEU11902.1 - 0.00077 19.9 4.2 0.0029 18.1 4.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 CrgA PF06781.12 OEU11902.1 - 0.13 12.4 0.4 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF2072 PF09845.9 OEU11903.1 - 0.33 11.2 3.0 1.3 9.3 3.0 2.0 1 1 0 1 1 1 0 Zn-ribbon containing protein Beta_helix PF13229.6 OEU11905.1 - 6.1e-05 22.9 12.7 6.1e-05 22.9 12.7 5.0 1 1 3 5 5 5 2 Right handed beta helix region CbiN PF02553.15 OEU11906.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN O-FucT PF10250.9 OEU11907.1 - 5.5e-22 78.9 1.8 1.7e-21 77.3 1.8 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SpoIIIAH PF12685.7 OEU11907.1 - 0.0088 15.9 3.1 0.017 15.0 0.7 2.4 2 0 0 2 2 2 1 SpoIIIAH-like protein Connexin PF00029.19 OEU11907.1 - 0.068 12.9 1.7 0.14 11.9 0.3 2.1 2 0 0 2 2 2 0 Connexin ILEI PF15711.5 OEU11907.1 - 0.089 13.3 0.2 0.34 11.4 0.2 2.0 1 0 0 1 1 1 0 Interleukin-like EMT inducer RPA43_OB PF17875.1 OEU11907.1 - 8.2 7.1 11.9 10 6.8 0.3 3.4 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Ski2_N PF17911.1 OEU11908.1 - 0.43 10.4 4.2 0.088 12.6 0.8 1.6 2 0 0 2 2 2 0 Ski2 N-terminal region BTB PF00651.31 OEU11909.1 - 1.3e-10 41.5 0.1 2.9e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 OEU11909.1 - 6.3e-06 26.3 0.3 2e-05 24.7 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Fe-S_biosyn PF01521.20 OEU11909.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Iron-sulphur cluster biosynthesis Ribosomal_S21 PF01165.20 OEU11910.1 - 1.7e-17 62.9 4.9 1.7e-17 62.9 4.9 1.9 1 1 1 2 2 2 1 Ribosomal protein S21 PPR_2 PF13041.6 OEU11911.1 - 1.6e-12 47.4 2.4 0.039 14.1 0.0 7.0 7 0 0 7 7 7 3 PPR repeat family PPR_1 PF12854.7 OEU11911.1 - 4.2e-08 32.8 0.0 1.8 8.4 0.0 6.4 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 OEU11911.1 - 0.00032 20.7 0.1 9.4 6.4 0.0 5.3 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.20 OEU11911.1 - 0.011 15.9 7.3 1.2 9.5 0.0 5.0 7 0 0 7 7 7 0 PPR repeat DUF5316 PF17247.2 OEU11912.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5316) PAH PF02671.21 OEU11913.1 - 1.8e-08 34.3 0.1 6.6e-08 32.6 0.1 2.0 1 0 0 1 1 1 1 Paired amphipathic helix repeat PPR_1 PF12854.7 OEU11916.1 - 1.3e-36 123.9 7.6 8.3e-05 22.2 0.0 9.0 8 3 1 9 9 9 7 PPR repeat PPR_2 PF13041.6 OEU11916.1 - 3.4e-28 97.6 10.1 1.7e-06 28.1 0.2 8.1 6 3 1 7 7 7 5 PPR repeat family PPR PF01535.20 OEU11916.1 - 1.6e-26 90.6 15.6 0.00065 19.8 0.0 10.8 10 2 0 10 10 10 6 PPR repeat PPR_3 PF13812.6 OEU11916.1 - 2.8e-24 85.0 3.6 4.3e-05 23.5 0.0 7.2 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU11916.1 - 2e-13 50.2 0.0 1.6e-05 24.4 0.0 4.1 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP Wzy_C_2 PF11846.8 OEU11916.1 - 1.1e-07 32.0 0.0 0.59 10.0 0.0 4.9 2 1 3 5 5 5 3 Virulence factor membrane-bound polymerase, C-terminal ENT PF03735.14 OEU11916.1 - 0.0053 16.8 0.3 24 5.1 0.0 4.5 5 0 0 5 5 5 0 ENT domain T4_Rnl2_C PF18043.1 OEU11916.1 - 0.12 12.5 1.5 3.3 7.9 0.0 3.3 3 1 0 3 3 3 0 T4 RNA ligase 2 C-terminal POP1 PF06978.11 OEU11917.1 - 0.0021 18.1 8.4 0.0021 18.1 8.4 5.8 6 1 0 6 6 6 1 Ribonucleases P/MRP protein subunit POP1 Pkinase_Tyr PF07714.17 OEU11918.1 - 3e-24 85.7 0.2 1.1e-22 80.6 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU11918.1 - 3.4e-23 82.3 0.1 5.2e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RRN3 PF05327.11 OEU11918.1 - 3 6.3 8.0 4.7 5.6 8.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDE_Tnp_1_7 PF13843.6 OEU11919.1 - 4.1e-14 52.6 0.0 5.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Ribosomal_S3Ae PF01015.18 OEU11922.1 - 3.2e-82 275.0 0.4 3.8e-82 274.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family IPT PF01745.16 OEU11922.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Ribosomal_S17 PF00366.20 OEU11923.1 - 2.7e-24 85.0 2.6 3e-24 84.9 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 PT PF04886.12 OEU11924.1 - 1.2e-08 34.4 76.8 0.33 10.5 13.1 10.0 9 2 0 9 9 9 8 PT repeat Pea-VEAacid PF08111.11 OEU11924.1 - 0.0051 17.0 7.8 2.9e+02 2.1 0.0 7.8 8 0 0 8 8 8 0 Pea-VEAacid family CRAL_TRIO PF00650.20 OEU11925.1 - 6.4e-07 29.2 0.2 2.3e-05 24.1 0.1 2.5 1 1 0 1 1 1 1 CRAL/TRIO domain Chromo_2 PF18704.1 OEU11925.1 - 4.2 7.7 7.6 36 4.7 0.1 3.7 2 1 0 2 2 2 0 Chromatin organization modifier domain 2 DLH PF01738.18 OEU11927.1 - 0.016 14.8 0.0 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family K_channel_TID PF07941.11 OEU11927.1 - 0.17 12.4 3.3 3.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Yae1_N PF09811.9 OEU11928.1 - 1.2e-10 40.9 32.6 0.00035 20.2 3.2 9.3 3 2 3 6 6 6 4 Essential protein Yae1, N terminal Transgly_assoc PF04226.13 OEU11928.1 - 1.3 9.3 31.7 1.5 9.1 2.7 6.5 1 1 2 3 3 3 0 Transglycosylase associated protein MspA PF09203.11 OEU11928.1 - 1.9 8.3 5.2 1e+02 2.7 5.2 2.7 1 1 0 1 1 1 0 MspA DUF697 PF05128.12 OEU11928.1 - 7.8 6.2 8.9 1.9 8.2 1.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF697) DUF1731 PF08338.11 OEU11929.1 - 3.1e-15 55.7 0.1 4.5e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) DUF3984 PF13136.6 OEU11930.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) PseudoU_synth_2 PF00849.22 OEU11931.1 - 4.3e-24 85.4 0.0 2.4e-22 79.7 0.0 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OEU11931.1 - 0.021 14.5 0.4 0.057 13.1 0.1 1.9 2 0 0 2 2 2 0 S4 domain 7tm_3 PF00003.22 OEU11932.1 - 3.3e-10 40.1 24.3 2.4e-09 37.3 24.3 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR LRR19-TM PF15176.6 OEU11932.1 - 0.2 11.7 4.2 0.83 9.7 0.0 3.2 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF4149 PF13664.6 OEU11932.1 - 3.4 8.0 8.1 3.7 7.9 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4149) Peptidase_S8 PF00082.22 OEU11933.1 - 1.6e-05 24.3 0.1 4.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Subtilase family UPF0029 PF01205.19 OEU11934.1 - 1.8e-24 86.1 0.0 3.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF4171 PF13775.6 OEU11934.1 - 2.1 8.8 6.6 6.5 7.2 6.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4171) Spermine_synth PF01564.17 OEU11936.1 - 1.2e-16 60.7 0.0 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 OEU11936.1 - 0.00049 20.3 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase UCMA PF17085.5 OEU11936.1 - 0.001 19.1 0.4 0.003 17.6 0.4 1.8 1 0 0 1 1 1 1 Unique cartilage matrix associated protein SET PF00856.28 OEU11936.1 - 0.031 14.7 0.6 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 SET domain Methyltransf_11 PF08241.12 OEU11936.1 - 0.056 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Agenet PF05641.12 OEU11936.1 - 0.1 13.1 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Agenet domain Chloroa_b-bind PF00504.21 OEU11937.1 - 5.2e-31 108.4 0.2 6.7e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HALZ PF02183.18 OEU11938.1 - 0.18 12.0 8.2 1.3 9.3 0.3 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper MAD PF05557.13 OEU11938.1 - 1.9 6.8 38.1 0.003 16.0 26.8 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein Chloroa_b-bind PF00504.21 OEU11939.1 - 1.3e-35 123.3 0.0 2.1e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PT PF04886.12 OEU11941.1 - 0.002 17.6 4.7 0.0031 17.0 4.7 1.2 1 0 0 1 1 1 1 PT repeat HSF_DNA-bind PF00447.17 OEU11943.1 - 6.2e-10 39.6 0.3 7.8e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding YjgF_endoribonc PF14588.6 OEU11944.1 - 1.2e-16 61.1 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 OEU11944.1 - 6.1e-09 35.9 0.0 1.1e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 Endoribonuclease L-PSP PT PF04886.12 OEU11945.1 - 9.8e-07 28.2 62.9 2.6e-05 23.6 29.6 3.8 2 2 1 3 3 3 2 PT repeat ShK PF01549.24 OEU11945.1 - 3.6e-06 27.4 17.9 0.00055 20.4 4.5 2.5 2 0 0 2 2 2 2 ShK domain-like SPX PF03105.19 OEU11945.1 - 6 6.7 21.2 9.6 6.0 21.2 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 OEU11945.1 - 6.4 5.5 11.2 8 5.2 11.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nsp1_C PF05064.13 OEU11948.1 - 0.062 13.1 0.8 2.3 8.0 0.5 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region DDE_Tnp_1 PF01609.21 OEU11949.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain BAR_2 PF10455.9 OEU11949.1 - 0.1 11.7 0.8 13 4.8 0.0 3.0 3 1 1 4 4 4 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF285 PF03382.14 OEU11950.1 - 1.1e-54 183.3 32.1 2.7e-30 104.6 12.7 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Prok_Ub PF14454.6 OEU11950.1 - 0.056 13.1 0.4 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic Ubiquitin Atg29_N PF18388.1 OEU11950.1 - 0.11 12.3 1.5 0.31 10.9 0.1 2.2 2 0 0 2 2 2 0 Atg29 N-terminal domain FeThRed_B PF02943.15 OEU11951.1 - 0.0078 16.2 0.2 0.55 10.3 0.1 2.2 2 0 0 2 2 2 2 Ferredoxin thioredoxin reductase catalytic beta chain Corazonin PF17308.2 OEU11951.1 - 0.68 10.3 5.9 2.2 8.6 2.9 2.0 1 1 1 2 2 2 0 Pro-corazonin POT1 PF02765.17 OEU11953.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 TRAP-delta PF05404.12 OEU11955.1 - 0.041 13.4 0.1 0.096 12.2 0.1 1.6 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) SLATT_5 PF18160.1 OEU11958.1 - 2.8e-06 26.8 0.2 4.1e-05 23.0 0.5 2.5 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 SLATT_4 PF18186.1 OEU11958.1 - 0.0022 17.7 0.3 0.0048 16.6 0.3 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 HSL_N PF06350.12 OEU11958.1 - 0.057 12.4 1.5 3.1 6.7 0.2 2.3 2 1 0 2 2 2 0 Hormone-sensitive lipase (HSL) N-terminus DUF4231 PF14015.6 OEU11958.1 - 0.071 13.6 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Neur_chan_LBD PF02931.23 OEU11960.1 - 1.7e-30 106.1 0.0 5.5e-30 104.4 0.0 1.9 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OEU11960.1 - 1.8e-09 38.0 9.0 6.9e-09 36.1 0.0 3.0 2 2 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region R3H-assoc PF13902.6 OEU11961.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain PMP22_Claudin PF00822.20 OEU11962.1 - 0.089 12.7 1.1 0.21 11.4 0.0 2.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family ABC2_membrane_3 PF12698.7 OEU11962.1 - 0.83 8.7 7.2 1.1 8.3 7.2 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4064 PF13273.6 OEU11962.1 - 0.9 9.8 8.4 0.64 10.3 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4592 PF15262.6 OEU11963.1 - 3.6 8.3 14.5 1 10.0 8.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4592) LPMO_10 PF03067.15 OEU11964.1 - 5.3e-05 24.0 0.0 5.7e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Y_phosphatase3 PF13350.6 OEU11966.1 - 4.9e-05 23.4 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OEU11966.1 - 0.0049 16.5 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OEU11966.1 - 0.028 14.6 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Tnp_P_element_C PF12596.8 OEU11966.1 - 0.046 14.3 0.1 0.14 12.7 0.1 1.8 1 0 0 1 1 1 0 87kDa Transposase DSPc PF00782.20 OEU11966.1 - 0.069 13.0 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2046 PF09755.9 OEU11969.1 - 0.0095 15.2 0.3 0.018 14.3 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) HAUS5 PF14817.6 OEU11969.1 - 0.011 14.5 0.3 0.014 14.1 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 COG5 PF10392.9 OEU11969.1 - 0.04 14.1 0.6 0.04 14.1 0.6 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HeLo PF14479.6 OEU11969.1 - 0.043 13.6 0.7 0.099 12.5 0.1 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation GCIP PF13324.6 OEU11969.1 - 0.28 10.7 8.9 0.52 9.9 8.9 1.5 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3391 PF11871.8 OEU11970.1 - 2.9 8.5 7.7 4.3 7.9 6.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) ELFV_dehydrog PF00208.21 OEU11971.1 - 2.7e-72 243.4 1.4 3.3e-72 243.1 1.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OEU11971.1 - 6.4e-47 158.7 0.0 1.6e-46 157.4 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 OEU11971.1 - 0.064 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OEU11971.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Prominin PF05478.11 OEU11972.1 - 0.037 12.0 0.2 0.05 11.6 0.2 1.2 1 0 0 1 1 1 0 Prominin DUF3671 PF12420.8 OEU11972.1 - 0.19 11.8 2.3 2.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF4366 PF14283.6 OEU11973.1 - 2.2 8.3 6.2 1.1 9.2 3.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Bee_toxin PF17454.2 OEU11973.1 - 3.9 7.6 9.6 12 6.0 0.3 3.9 3 0 0 3 3 3 0 Honey bee toxin Sulfotransfer_4 PF17784.1 OEU11974.1 - 4.5e-06 26.7 0.1 2.4e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Clathrin_lg_ch PF01086.17 OEU11974.1 - 0.034 14.2 1.8 0.058 13.4 1.8 1.3 1 0 0 1 1 1 0 Clathrin light chain HTH_38 PF13936.6 OEU11975.1 - 0.096 12.5 4.7 4.3 7.2 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Helicase_C PF00271.31 OEU11976.1 - 3.4e-16 59.6 0.0 7.7e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OEU11976.1 - 1.3e-13 51.1 0.1 1.3e-13 51.1 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OEU11976.1 - 2e-08 34.2 0.0 5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OEU11976.1 - 1.8e-05 25.1 0.0 5.1e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU11976.1 - 0.00025 21.3 0.4 0.00079 19.7 0.4 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 OEU11976.1 - 0.00087 18.4 0.1 0.0018 17.4 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 OEU11976.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Helicase_RecD PF05127.14 OEU11976.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Helicase BUD22 PF09073.10 OEU11976.1 - 0.14 11.4 3.0 0.3 10.4 3.0 1.4 1 0 0 1 1 1 0 BUD22 DUF2075 PF09848.9 OEU11976.1 - 1.1 8.5 3.3 0.28 10.4 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG2_2 PF13772.6 OEU11977.1 - 0.00086 19.7 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family Presenilin PF01080.17 OEU11977.1 - 0.19 10.5 8.7 0.31 9.8 8.7 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OEU11977.1 - 0.98 7.9 8.3 1.5 7.3 8.3 1.4 1 0 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 OEU11977.1 - 3 8.3 7.7 15 6.0 2.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ABC_sub_bind PF04392.12 OEU11980.1 - 0.0068 15.7 0.8 0.01 15.1 0.8 1.2 1 0 0 1 1 1 1 ABC transporter substrate binding protein DUF4235 PF14019.6 OEU11980.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) KH_1 PF00013.29 OEU11982.1 - 6.1e-29 99.6 11.6 4.3e-10 39.3 3.0 3.6 3 1 0 3 3 3 3 KH domain KH_2 PF07650.17 OEU11982.1 - 2.5e-07 30.4 1.1 0.002 17.9 0.1 3.5 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 OEU11982.1 - 0.0032 17.3 0.1 0.024 14.5 0.1 2.3 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 OEU11982.1 - 0.015 15.3 5.6 6.1 7.0 0.3 3.7 4 0 0 4 4 4 0 NusA-like KH domain B277 PF17623.2 OEU11982.1 - 0.41 9.7 2.2 0.72 8.9 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function Macoilin PF09726.9 OEU11982.1 - 2.6 6.5 4.7 4.1 5.9 4.7 1.3 1 0 0 1 1 1 0 Macoilin family LRR_4 PF12799.7 OEU11983.1 - 0.00046 20.5 6.4 0.34 11.4 0.4 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU11983.1 - 0.36 10.6 4.0 2.7 7.8 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat DUF4449 PF14613.6 OEU11983.1 - 0.7 10.0 9.4 1.2 9.3 6.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4449) SKG6 PF08693.10 OEU11983.1 - 0.99 8.9 3.9 1.7 8.1 3.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_1 PF00560.33 OEU11983.1 - 1.3 9.8 8.3 30 5.7 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 OEU11983.1 - 2.2 8.6 4.8 8.5 6.7 0.2 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 OEU11984.1 - 8.1e-24 84.4 0.0 9.8e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU11984.1 - 7.8e-14 51.6 0.0 9.8e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU11984.1 - 7.3e-06 26.1 0.1 0.00054 20.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU11984.1 - 1.5e-05 24.0 0.0 1.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OEU11984.1 - 0.022 14.4 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Acyl_transf_3 PF01757.22 OEU11986.1 - 9.4e-23 80.8 42.7 9.4e-23 80.8 42.7 2.1 2 0 0 2 2 2 2 Acyltransferase family PEP-CTERM PF07589.11 OEU11986.1 - 0.8 9.9 2.7 2.7 8.2 2.7 1.9 1 0 0 1 1 1 0 PEP-CTERM motif Ca_chan_IQ PF08763.11 OEU11987.1 - 0.061 13.5 1.0 0.077 13.2 0.8 1.3 1 1 0 1 1 1 0 Voltage gated calcium channel IQ domain Cupin_8 PF13621.6 OEU11989.1 - 1.4e-22 80.7 3.7 4.4e-21 75.7 3.7 2.4 1 1 0 1 1 1 1 Cupin-like domain Connexin PF00029.19 OEU11989.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.1 3 0 0 3 3 3 0 Connexin JmjC PF02373.22 OEU11989.1 - 0.22 11.9 3.1 0.18 12.2 0.6 2.2 2 1 0 2 2 2 0 JmjC domain, hydroxylase E3_UbLigase_RBR PF18091.1 OEU11991.1 - 0.06 13.5 1.3 0.06 13.5 1.3 2.3 2 1 1 3 3 3 0 E3 Ubiquitin Ligase RBR C-terminal domain DUF3446 PF11928.8 OEU11991.1 - 0.65 10.3 14.4 0.67 10.3 5.5 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF1635 PF07795.11 OEU11991.1 - 0.76 9.6 11.7 2.3 8.0 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Lin-8 PF03353.15 OEU11991.1 - 4.7 6.7 19.0 37 3.8 15.9 2.0 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist Aldo_ket_red PF00248.21 OEU11993.1 - 1.1e-15 57.6 0.0 7.1e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family FSA_C PF10479.9 OEU11993.1 - 0.6 8.2 19.2 0.96 7.5 19.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NUDE_C PF04880.13 OEU11993.1 - 8.6 6.8 10.2 19 5.7 10.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Sulfotransfer_3 PF13469.6 OEU11994.1 - 3.4e-12 47.2 5.7 1.1e-10 42.3 0.3 2.5 3 0 0 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 OEU11994.1 - 4.4e-07 29.7 14.8 8.7e-05 22.1 3.1 2.8 3 1 0 3 3 3 2 Sulfotransferase domain TORC_M PF12885.7 OEU11994.1 - 0.051 13.5 5.4 0.12 12.3 5.4 1.6 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DELLA PF12041.8 OEU11994.1 - 0.085 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal EPL1 PF10513.9 OEU11994.1 - 0.27 11.6 10.6 1.2e+02 2.9 10.6 2.7 1 1 0 1 1 1 0 Enhancer of polycomb-like Sulfotransfer_2 PF03567.14 OEU11994.1 - 1.1 9.1 20.2 0.016 15.1 7.4 3.4 3 1 0 3 3 3 0 Sulfotransferase family Jnk-SapK_ap_N PF09744.9 OEU11998.1 - 0.016 15.4 19.2 0.031 14.5 19.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF572 PF04502.13 OEU11998.1 - 0.026 14.2 8.3 0.036 13.7 8.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SKG6 PF08693.10 OEU11998.1 - 0.2 11.1 2.1 0.44 10.0 2.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2570 PF10828.8 OEU11998.1 - 3.4 7.5 9.5 17 5.2 9.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Gly_transf_sug PF04488.15 OEU11999.1 - 5.7e-08 33.3 0.3 5.7e-08 33.3 0.3 1.9 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU11999.1 - 0.0042 16.5 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF5352 PF17303.2 OEU12002.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5352) Mucin PF01456.17 OEU12002.1 - 1.2 9.1 8.4 0.057 13.4 2.2 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Striatin PF08232.12 OEU12002.1 - 1.4 9.5 7.0 5 7.7 2.7 2.2 2 0 0 2 2 2 0 Striatin family PDDEXK_6 PF04720.12 OEU12002.1 - 4.6 7.1 10.4 0.98 9.3 0.5 2.3 2 1 0 2 2 2 0 PDDEXK-like family of unknown function DUF775 PF05603.12 OEU12002.1 - 8.6 5.8 7.9 3.1 7.3 4.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF775) DUF4235 PF14019.6 OEU12004.1 - 0.0072 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) PhaC_N PF07167.13 OEU12004.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Shadoo PF14999.6 OEU12004.1 - 0.14 12.2 0.3 0.74 9.9 0.1 2.0 2 1 0 2 2 2 0 Shadow of prion protein, neuroprotective Thioredoxin_4 PF13462.6 OEU12005.1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin DUF1269 PF06897.12 OEU12006.1 - 0.00082 19.6 0.8 0.0018 18.5 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 OEU12006.1 - 0.0035 17.2 12.6 0.0094 15.8 1.0 2.3 2 0 0 2 2 2 2 Glycine zipper 2TM domain DUF3482 PF11981.8 OEU12006.1 - 0.0051 16.3 5.2 0.0051 16.3 5.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3482) Bacteriocin_IIc PF10439.9 OEU12006.1 - 0.019 15.1 11.2 0.029 14.5 11.2 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 OEU12006.1 - 0.037 13.8 19.0 0.084 12.6 19.0 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper Phage_holin_2_4 PF16082.5 OEU12006.1 - 0.13 12.0 0.2 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Gly-zipper_Omp PF13488.6 OEU12006.1 - 0.21 11.6 18.6 0.68 10.0 17.7 2.1 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 OEU12006.1 - 1.3 8.9 19.2 5.7 6.8 19.4 1.8 1 1 0 1 1 1 0 Glycine-zipper domain PGPGW PF09656.10 OEU12007.1 - 7.1e-05 22.2 1.0 0.00011 21.6 1.0 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) SDA1 PF05285.12 OEU12007.1 - 0.00099 18.6 3.2 0.0011 18.5 3.2 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OEU12007.1 - 0.13 10.5 3.2 0.14 10.4 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ABM PF03992.16 OEU12008.1 - 0.00022 21.3 0.1 0.00026 21.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 OEU12008.1 - 0.00038 20.8 0.1 0.00044 20.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Avidin PF01382.17 OEU12008.1 - 0.044 14.3 0.1 0.05 14.1 0.1 1.1 1 0 0 1 1 1 0 Avidin family Dabb PF07876.12 OEU12008.1 - 0.055 14.1 0.0 0.096 13.3 0.0 1.5 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain PfkB PF00294.24 OEU12009.1 - 7.1 5.8 9.0 1.7 7.9 5.4 1.8 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Trypsin PF00089.26 OEU12010.1 - 6e-23 81.8 0.0 1.6e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU12010.1 - 0.0037 18.2 0.0 0.014 16.3 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain APOBEC1 PF18769.1 OEU12010.1 - 0.029 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 Thioredoxin PF00085.20 OEU12011.1 - 9.3e-24 83.4 0.1 1.2e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OEU12011.1 - 1.8e-06 27.9 0.0 2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OEU12011.1 - 2.2e-05 24.2 0.1 2.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU12011.1 - 7.9e-05 23.1 0.2 0.00015 22.1 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU12011.1 - 0.00011 22.4 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU12011.1 - 0.00021 21.0 0.1 0.00025 20.8 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OEU12011.1 - 0.0032 17.6 0.1 0.0052 16.9 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OEU12011.1 - 0.0043 16.4 0.0 0.0048 16.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 OEU12011.1 - 0.05 13.4 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 PCYCGC PF13798.6 OEU12011.1 - 0.05 13.4 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif ABC_sub_bind PF04392.12 OEU12012.1 - 0.034 13.4 1.2 0.052 12.8 1.2 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein DUF4235 PF14019.6 OEU12012.1 - 0.042 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF2797 PF10977.8 OEU12013.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2797) HIP1_clath_bdg PF16515.5 OEU12014.1 - 0.0012 19.4 1.3 0.0012 19.4 1.3 3.1 2 1 1 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 TMEM251 PF15190.6 OEU12015.1 - 0.033 14.1 2.1 0.041 13.8 2.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 251 Prominin PF05478.11 OEU12015.1 - 0.042 11.8 2.0 0.046 11.7 2.0 1.1 1 0 0 1 1 1 0 Prominin DUF2116 PF09889.9 OEU12015.1 - 0.75 9.8 3.7 8 6.5 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ThrE PF06738.12 OEU12016.1 - 5.2e-18 65.3 5.6 5.2e-18 65.3 5.6 2.8 2 1 0 2 2 2 2 Putative threonine/serine exporter PNTB_4TM PF12769.7 OEU12016.1 - 0.0033 17.8 1.6 0.014 15.8 1.6 2.2 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2TM PF13239.6 OEU12017.1 - 1.3 9.3 4.3 2.8 8.3 4.3 1.4 1 0 0 1 1 1 0 2TM domain Metallophos PF00149.28 OEU12018.1 - 7.5e-06 26.6 2.0 8.7e-05 23.1 2.1 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EarP PF10093.9 OEU12019.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Macoilin PF09726.9 OEU12019.1 - 3.1 6.3 21.3 3.6 6.0 21.3 1.2 1 0 0 1 1 1 0 Macoilin family Gly-zipper_Omp PF13488.6 OEU12020.1 - 0.035 14.1 6.3 0.059 13.4 6.3 1.4 1 0 0 1 1 1 0 Glycine zipper DUF2407_C PF13373.6 OEU12020.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF1269 PF06897.12 OEU12020.1 - 0.13 12.5 0.2 0.27 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.9 OEU12020.1 - 0.3 11.2 7.6 0.55 10.4 7.6 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide GFD1 PF17331.2 OEU12020.1 - 0.62 10.3 3.2 1.2 9.4 3.2 1.4 1 0 0 1 1 1 0 GFD1 mRNA transport factor Rick_17kDa_Anti PF05433.15 OEU12020.1 - 3.6 7.5 10.4 10 6.1 0.7 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF5600 PF18150.1 OEU12021.1 - 0.0028 18.2 2.8 0.003 18.1 1.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5600) DUF1947 PF09183.10 OEU12021.1 - 7.7 6.9 10.3 0.28 11.5 1.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Thioredoxin PF00085.20 OEU12023.1 - 3.9e-09 36.4 0.1 4.7e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU12023.1 - 0.00051 20.3 0.1 0.0008 19.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like LRIF1 PF15741.5 OEU12024.1 - 0.0052 15.4 1.6 0.007 15.0 1.6 1.1 1 0 0 1 1 1 1 Ligand-dependent nuclear receptor-interacting factor 1 WD40_alt PF14077.6 OEU12025.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Alternative WD40 repeat motif zf-rbx1 PF12678.7 OEU12026.1 - 3.4e-09 36.8 5.5 1.4e-08 34.9 5.5 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OEU12026.1 - 1.3e-08 35.0 1.4 1.3e-08 35.0 1.4 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU12026.1 - 1.3e-07 31.4 1.6 1.3e-07 31.4 1.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU12026.1 - 2.2e-05 24.4 1.1 5.9e-05 23.1 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OEU12026.1 - 0.00022 21.1 1.9 0.00022 21.1 1.9 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU12026.1 - 0.0003 20.6 7.9 0.0003 20.6 7.9 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OEU12026.1 - 0.00035 20.3 0.7 0.00092 19.0 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OEU12026.1 - 0.00057 19.6 4.3 0.0092 15.7 0.6 2.8 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OEU12026.1 - 0.00088 18.8 1.4 0.00088 18.8 1.4 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OEU12026.1 - 0.001 19.0 1.4 0.001 19.0 1.4 3.4 4 0 0 4 4 3 1 RING-type zinc-finger Myc_N PF01056.18 OEU12026.1 - 0.0075 16.2 4.4 0.0075 16.2 4.4 5.0 2 1 2 4 4 3 1 Myc amino-terminal region Prok-RING_4 PF14447.6 OEU12026.1 - 0.012 15.4 1.1 0.012 15.4 1.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 OEU12026.1 - 0.017 15.4 2.4 0.06 13.7 2.4 1.9 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 OEU12026.1 - 0.019 14.8 0.5 0.019 14.8 0.5 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OEU12026.1 - 0.13 12.4 5.1 0.4 10.9 5.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OEU12026.1 - 0.14 12.4 5.9 0.1 12.8 2.4 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OEU12026.1 - 0.24 11.5 8.3 0.045 13.9 3.7 2.3 2 0 0 2 2 2 0 RING-variant domain Utp14 PF04615.13 OEU12028.1 - 1.9 6.9 35.0 2.6 6.5 35.0 1.1 1 0 0 1 1 1 0 Utp14 protein Myb_DNA-binding PF00249.31 OEU12030.1 - 2e-30 104.7 0.1 0.0018 18.4 0.0 7.7 7 0 0 7 7 7 7 Myb-like DNA-binding domain LBR_tudor PF09465.10 OEU12030.1 - 2.4e-05 24.1 3.9 9.5e-05 22.1 0.7 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Myb_DNA-bind_6 PF13921.6 OEU12030.1 - 0.0005 20.3 21.7 3.9 7.8 0.0 9.7 9 1 0 9 9 9 3 Myb-like DNA-binding domain Tudor_3 PF18115.1 OEU12030.1 - 0.0033 17.2 1.3 1.2 9.0 0.1 2.7 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain Myb_DNA-bind_7 PF15963.5 OEU12030.1 - 0.088 12.7 0.0 0.092 12.7 0.0 11.6 11 4 3 14 14 14 0 Myb DNA-binding like Agenet PF05641.12 OEU12030.1 - 0.12 12.9 7.9 1.2 9.6 0.1 3.9 3 0 0 3 3 3 0 Agenet domain Methyltransf_24 PF13578.6 OEU12031.1 - 0.00026 22.0 0.0 0.00027 21.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PBP1_TM PF14812.6 OEU12033.1 - 0.00041 20.7 8.8 0.0027 18.0 0.2 3.8 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SNARE PF05739.19 OEU12033.1 - 0.0086 16.0 0.5 0.0086 16.0 0.5 2.1 2 0 0 2 2 2 1 SNARE domain Orf78 PF06024.12 OEU12033.1 - 0.023 15.0 0.2 0.023 15.0 0.2 3.2 2 1 1 3 3 3 0 Orf78 (ac78) ABC2_membrane_2 PF12679.7 OEU12033.1 - 0.055 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CP12 PF02672.15 OEU12039.1 - 1.7e-06 28.7 3.6 0.016 16.0 0.1 2.7 3 0 0 3 3 3 2 CP12 domain PMR5N PF14416.6 OEU12039.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 PMR5 N terminal Domain Sigma_reg_C PF13791.6 OEU12039.1 - 0.38 10.9 5.4 0.12 12.6 1.9 1.7 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Redoxin PF08534.10 OEU12040.1 - 5.5e-33 113.7 0.0 6.4e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU12040.1 - 1.7e-14 53.8 0.0 1.9e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU12041.1 - 1.2e-32 112.7 0.0 1.5e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU12041.1 - 3.5e-14 52.8 0.0 4.4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Heme_oxygenase PF01126.20 OEU12042.1 - 3.2e-47 161.0 0.1 1.3e-23 83.9 0.0 2.1 2 0 0 2 2 2 2 Heme oxygenase Sp38 PF07354.12 OEU12042.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Rad21_Rec8_N PF04825.13 OEU12043.1 - 5e-39 132.9 0.0 1e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OEU12043.1 - 6.3e-12 44.6 0.0 2.3e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SPT6_acidic PF14632.6 OEU12043.1 - 0.036 14.6 0.5 0.036 14.6 0.5 6.0 4 1 2 6 6 6 0 Acidic N-terminal SPT6 Glyco_transf_10 PF00852.19 OEU12044.1 - 1.9e-20 73.3 4.3 1.3e-14 54.3 0.1 3.6 2 2 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term AgrB PF04647.15 OEU12044.1 - 0.021 14.1 0.6 0.044 13.1 0.6 1.4 1 0 0 1 1 1 0 Accessory gene regulator B PD40 PF07676.12 OEU12045.1 - 6.3 6.9 7.4 80 3.4 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 OEU12046.1 - 6.9e-25 87.7 40.6 6.9e-25 87.7 40.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ESP PF16590.5 OEU12047.1 - 2.7 8.3 6.1 1.1 9.6 2.0 2.3 2 0 0 2 2 2 0 Exocrine gland-secreting peptide PT PF04886.12 OEU12048.1 - 0.13 11.8 1.7 1.2 8.8 1.7 2.2 1 1 0 1 1 1 0 PT repeat Fasciclin PF02469.22 OEU12049.1 - 3.2e-35 121.1 0.0 4.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain eIF3_p135 PF12807.7 OEU12050.1 - 0.53 10.3 5.9 1.9 8.5 1.4 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 SUIM_assoc PF16619.5 OEU12050.1 - 5.9 7.0 14.2 4.9 7.3 2.4 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ubiquitin PF00240.23 OEU12051.1 - 1.2e-34 117.8 0.4 1.3e-34 117.7 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU12051.1 - 5.7e-17 61.3 0.7 6.2e-17 61.2 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU12051.1 - 2.4e-06 27.9 0.1 9.9e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU12051.1 - 0.0009 19.1 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU12051.1 - 0.0023 18.0 0.1 0.005 16.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OEU12051.1 - 0.0036 17.6 0.0 0.0044 17.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU12051.1 - 0.0045 17.0 0.2 2.3 8.4 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 OEU12051.1 - 0.024 15.2 0.0 0.026 15.1 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Glycos_transf_2 PF00535.26 OEU12052.1 - 7.5e-06 25.9 0.2 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 TIG PF01833.24 OEU12053.1 - 5.4e-10 39.2 2.1 8.1e-10 38.6 0.5 2.2 2 0 0 2 2 2 1 IPT/TIG domain TbpB_A PF17484.2 OEU12053.1 - 0.00038 21.2 2.5 0.052 14.3 0.2 3.0 3 0 0 3 3 3 2 N-Lobe handle Tf-binding protein B DUF4969 PF16339.5 OEU12053.1 - 0.006 16.9 1.4 0.006 16.9 1.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4969) Methyltransf_32 PF13679.6 OEU12054.1 - 1.6e-18 67.2 0.3 1.6e-18 67.2 0.3 1.8 2 0 0 2 2 2 1 Methyltransferase domain TRM13 PF05206.14 OEU12054.1 - 0.00015 21.4 0.3 0.071 12.6 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase TRM13 DUF4745 PF15923.5 OEU12054.1 - 0.054 13.5 1.2 1.5 8.8 0.0 3.4 3 1 0 4 4 4 0 Domain of unknown function (DUF4745) LRR_8 PF13855.6 OEU12055.1 - 7.4e-15 54.5 10.5 4.1e-06 26.5 0.3 4.1 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OEU12055.1 - 7.8e-10 38.9 14.1 0.019 15.4 0.0 5.6 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU12055.1 - 4.1e-08 32.7 2.4 3.4 8.6 0.1 6.4 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU12055.1 - 0.12 12.5 7.5 5.3 7.4 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat WBP-1 PF11669.8 OEU12056.1 - 0.29 11.8 6.2 3.8 8.2 0.3 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 Neur_chan_memb PF02932.16 OEU12056.1 - 0.34 10.9 9.2 0.39 10.7 9.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region REV PF00424.18 OEU12056.1 - 1.4 9.0 9.5 0.72 9.9 1.5 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) SPT16 PF08644.11 OEU12056.1 - 1.5 9.0 9.3 0.26 11.5 3.7 2.1 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4834 PF16118.5 OEU12056.1 - 5.2 8.1 13.8 2.4 9.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CtaG_Cox11 PF04442.14 OEU12056.1 - 8.1 6.5 7.1 5.4 7.0 1.9 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein CtaG/Cox11 Trypsin PF00089.26 OEU12057.1 - 2.1e-42 145.4 2.6 4.3e-42 144.4 2.6 1.5 1 0 0 1 1 1 1 Trypsin PT PF04886.12 OEU12057.1 - 0.0014 18.1 19.4 0.0014 18.1 19.4 2.3 2 0 0 2 2 2 1 PT repeat DUF5643 PF18705.1 OEU12057.1 - 0.11 12.5 0.4 0.29 11.1 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5643) CHASE3 PF05227.13 OEU12058.1 - 0.2 11.6 5.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 CHASE3 domain Clr2 PF10383.9 OEU12058.1 - 0.3 11.9 1.4 0.59 10.9 1.4 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 PNPase_C PF12111.8 OEU12058.1 - 0.84 9.1 3.4 0.38 10.2 0.8 1.7 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal LAMTOR PF15454.6 OEU12060.1 - 0.012 16.2 0.3 0.012 16.2 0.3 2.0 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UPF0561 PF10573.9 OEU12060.1 - 0.058 13.5 2.2 0.057 13.5 1.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 DUF3246 PF11596.8 OEU12060.1 - 2.4 7.5 12.5 4.4 6.7 12.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Macoilin PF09726.9 OEU12060.1 - 2.8 6.4 6.8 3 6.3 6.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF3439 PF11921.8 OEU12061.1 - 0.022 14.7 5.4 0.045 13.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LEA_2 PF03168.13 OEU12061.1 - 0.17 12.5 1.8 0.53 10.8 0.3 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein DUF3566 PF12089.8 OEU12063.1 - 0.027 14.8 1.0 1.9 8.8 0.0 2.9 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Ninjurin PF04923.12 OEU12063.1 - 0.12 12.3 1.9 2.9 7.9 0.4 2.1 2 0 0 2 2 2 0 Ninjurin MpPF26 PF07666.11 OEU12063.1 - 0.24 11.5 7.1 0.091 12.9 1.4 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 FtsX PF02687.21 OEU12063.1 - 0.24 11.9 4.7 2.5 8.6 0.1 2.9 3 0 0 3 3 3 0 FtsX-like permease family DUF443 PF04276.12 OEU12063.1 - 1.1 9.0 9.7 0.14 11.9 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF443) Met_10 PF02475.16 OEU12064.1 - 2.2e-21 76.5 0.4 1.6e-11 44.3 0.0 4.6 4 2 1 5 5 5 3 Met-10+ like-protein AHSP PF09236.10 OEU12064.1 - 0.045 14.2 0.1 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein SR-25 PF10500.9 OEU12064.1 - 0.74 9.4 30.2 0.03 13.9 3.6 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2514 PF10721.9 OEU12065.1 - 0.3 11.1 0.1 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) TMEM171 PF15471.6 OEU12065.1 - 0.52 9.3 3.3 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 cwf18 PF08315.12 OEU12065.1 - 0.83 10.3 10.8 1 10.0 5.2 2.4 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor Presenilin PF01080.17 OEU12065.1 - 1.3 7.7 14.9 2.8 6.6 7.2 2.3 2 0 0 2 2 2 0 Presenilin NINJA_B PF16136.5 OEU12065.1 - 3 8.2 11.4 0.35 11.3 0.5 2.6 2 0 0 2 2 2 0 Putative nuclear localisation signal IMUP PF15761.5 OEU12065.1 - 3.5 8.3 13.9 0.53 11.0 5.6 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4064 PF13273.6 OEU12065.1 - 4 7.8 5.8 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) OAD_gamma PF04277.13 OEU12065.1 - 4 8.1 4.7 8.4 7.1 0.2 3.1 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Conotoxin PF02950.17 OEU12065.1 - 7.5 7.7 5.1 10 7.2 0.0 3.1 3 0 0 3 3 3 0 Conotoxin Mis14 PF08641.12 OEU12067.1 - 0.008 16.5 2.0 0.008 16.5 2.0 1.9 2 1 0 2 2 2 1 Kinetochore protein Mis14 like DUF4746 PF15928.5 OEU12067.1 - 0.034 13.6 2.1 0.05 13.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BBS2_C PF14782.6 OEU12067.1 - 0.087 11.6 2.2 0.12 11.1 2.2 1.3 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal GTP-bdg_M PF16360.5 OEU12067.1 - 0.17 12.5 0.3 0.17 12.5 0.3 2.7 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region 2OG-FeII_Oxy_2 PF13532.6 OEU12068.1 - 2e-17 64.0 0.1 3e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRA PF06589.11 OEU12068.1 - 0.033 14.3 0.9 0.033 14.3 0.9 2.3 3 1 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Trypan_PARP PF05887.11 OEU12068.1 - 0.17 11.9 4.4 0.34 10.9 4.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Folate_carrier PF01770.18 OEU12068.1 - 0.96 8.1 2.6 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Reduced folate carrier BAG PF02179.16 OEU12069.1 - 1.6e-05 25.3 0.0 4.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 BAG domain DUF3494 PF11999.8 OEU12070.1 - 8.7e-30 103.9 11.0 1.6e-29 103.1 11.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) Gal_Lectin PF02140.18 OEU12071.1 - 9e-21 74.1 2.7 9e-21 74.1 2.7 1.3 1 1 0 1 1 1 1 Galactose binding lectin domain PT PF04886.12 OEU12072.1 - 1.9e-06 27.3 30.6 0.021 14.4 14.0 2.4 1 1 1 2 2 2 2 PT repeat Yae1_N PF09811.9 OEU12073.1 - 4.5e-05 23.0 49.8 15 5.4 2.7 12.4 1 1 1 2 2 2 1 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU12073.1 - 0.00022 21.4 0.0 3.2 7.9 0.0 4.6 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain Ntox25 PF15530.6 OEU12073.1 - 0.002 18.3 1.1 48 4.1 0.1 4.7 1 1 3 4 4 4 0 Bacterial toxin 25 MspA PF09203.11 OEU12073.1 - 0.0069 16.3 11.4 1e+03 -0.6 11.4 4.2 1 1 0 1 1 1 0 MspA FlgT_C PF16538.5 OEU12073.1 - 8.2 7.0 5.7 5.1e+02 1.3 0.0 5.0 1 1 5 7 7 7 0 Flagellar assembly protein T, C-terminal domain Transgly_assoc PF04226.13 OEU12073.1 - 8.2 6.8 31.1 56 4.1 0.4 8.6 1 1 2 3 3 3 0 Transglycosylase associated protein Fasciclin PF02469.22 OEU12076.1 - 1e-19 71.0 0.0 2.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU12076.1 - 1.8e-05 25.5 0.3 0.00017 22.3 0.3 2.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ABC_membrane_2 PF06472.15 OEU12076.1 - 0.056 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 PT PF04886.12 OEU12078.1 - 0.77 9.4 37.9 1.8e+04 -14.7 37.9 3.4 1 1 0 1 1 1 0 PT repeat CI-B14_5a PF07347.12 OEU12079.1 - 0.11 12.3 10.5 0.084 12.8 3.6 2.9 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Tetraspanin PF00335.20 OEU12079.1 - 0.12 12.1 0.0 2.2 8.0 0.7 2.3 2 1 0 2 2 2 0 Tetraspanin family Pox_Ag35 PF03286.14 OEU12080.1 - 0.16 11.8 2.8 0.28 11.0 2.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Collagen PF01391.18 OEU12082.1 - 1.3e-06 28.1 3.0 0.022 14.5 3.0 2.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF285 PF03382.14 OEU12083.1 - 1e-64 215.7 27.4 2.4e-30 104.8 5.4 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 BssS PF13991.6 OEU12083.1 - 0.37 10.9 1.0 19 5.4 0.0 3.7 4 1 1 5 5 5 0 BssS protein family PT PF04886.12 OEU12084.1 - 1.7e-13 49.8 103.9 0.0023 17.4 6.0 8.6 2 2 6 8 8 8 7 PT repeat SRP-alpha_N PF04086.13 OEU12086.1 - 0.74 9.7 7.1 2 8.3 0.9 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4925 PF16272.5 OEU12088.1 - 0.044 13.3 0.2 0.06 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) DDE_3 PF13358.6 OEU12089.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease Ribosomal_L31 PF01197.18 OEU12089.1 - 0.088 13.1 0.2 0.85 9.9 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein L31 Phage_G PF02306.15 OEU12090.1 - 0.014 15.2 4.2 7.3 6.3 1.8 3.3 3 0 0 3 3 3 0 Major spike protein (G protein) Doppel PF11466.8 OEU12091.1 - 0.53 10.0 1.8 0.76 9.5 0.5 1.8 2 0 0 2 2 2 0 Prion-like protein Doppel Glypican PF01153.19 OEU12092.1 - 4.1 6.1 16.2 0.33 9.7 5.1 2.0 1 1 1 2 2 2 0 Glypican Presenilin PF01080.17 OEU12092.1 - 7.5 5.2 13.5 12 4.6 13.5 1.3 1 0 0 1 1 1 0 Presenilin Ig_mannosidase PF17753.1 OEU12093.1 - 2.6e-06 27.1 0.0 8.9e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 OEU12093.1 - 0.0055 15.9 3.0 0.035 13.2 3.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain RVT_N PF13655.6 OEU12093.1 - 0.14 12.4 0.1 0.78 10.0 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase DUF2953 PF11167.8 OEU12094.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Mucin PF01456.17 OEU12095.1 - 1.3 9.0 52.0 0.26 11.3 9.6 4.6 4 0 0 4 4 4 0 Mucin-like glycoprotein Utp14 PF04615.13 OEU12096.1 - 1.2e-05 24.2 22.1 1.2e-05 24.2 22.1 1.6 1 1 0 1 1 1 1 Utp14 protein DUF2052 PF09747.9 OEU12096.1 - 0.01 15.9 12.4 0.01 15.9 12.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) 7tm_3 PF00003.22 OEU12097.1 - 1.9e-12 47.5 3.8 2.5e-12 47.1 3.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR HAUS-augmin3 PF14932.6 OEU12097.1 - 0.0014 18.3 3.3 0.0014 18.3 3.3 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 ABC2_membrane_5 PF13346.6 OEU12097.1 - 0.059 12.9 2.2 0.084 12.4 2.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Cyt_bd_oxida_II PF02322.15 OEU12097.1 - 0.076 12.4 0.6 0.092 12.1 0.6 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF4407 PF14362.6 OEU12097.1 - 0.11 11.9 2.2 0.16 11.3 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OEU12097.1 - 0.16 9.8 2.4 0.26 9.2 2.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 OEU12097.1 - 5.9 6.7 10.6 2.9 7.7 7.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Mem_trans PF03547.18 OEU12098.1 - 7.9e-09 34.4 21.2 2.4e-06 26.2 10.5 3.2 1 1 1 2 2 2 2 Membrane transport protein ShK PF01549.24 OEU12099.1 - 9e-12 45.3 28.8 1.1e-05 25.8 12.2 2.4 2 0 0 2 2 2 2 ShK domain-like zf-CCCH PF00642.24 OEU12099.1 - 0.00035 20.4 1.1 0.23 11.4 0.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2043 PF09740.9 OEU12099.1 - 0.33 11.6 7.2 0.56 10.9 0.5 3.4 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2043) DUF1660 PF07874.11 OEU12099.1 - 4 8.0 12.1 11 6.5 1.0 2.8 2 0 0 2 2 2 0 Prophage protein (DUF1660) DUF2981 PF11200.8 OEU12099.1 - 6.9 6.3 11.1 9.4 5.9 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PBP1_TM PF14812.6 OEU12100.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5415 PF17436.2 OEU12102.1 - 0.0043 17.1 0.0 12 6.0 0.0 3.3 3 0 0 3 3 3 2 Family of unknown function (DUF5415) DUF1639 PF07797.14 OEU12102.1 - 8.1 6.5 11.0 42 4.2 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1639) CAV_VP3 PF04771.12 OEU12103.1 - 0.087 13.0 0.1 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Chicken anaemia virus VP-3 protein DUF1980 PF09323.10 OEU12104.1 - 0.24 11.3 4.2 0.29 11.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DPM3 PF08285.11 OEU12104.1 - 3.6 7.9 12.8 0.18 12.0 2.2 2.9 1 1 2 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PWI PF01480.17 OEU12105.1 - 0.059 13.7 0.0 5.9 7.3 0.0 3.1 3 0 0 3 3 3 0 PWI domain CCDC24 PF15669.5 OEU12107.1 - 0.012 15.5 0.8 0.012 15.5 0.8 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family CRAL_TRIO_N PF03765.15 OEU12107.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain zf-MYND PF01753.18 OEU12109.1 - 3.8e-06 26.9 7.7 1e-05 25.5 7.7 1.7 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 OEU12109.1 - 1.7e-05 24.6 0.0 0.095 12.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU12109.1 - 0.00012 21.8 0.0 0.12 12.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU12109.1 - 0.00014 21.8 0.0 0.054 13.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2802 PF10975.8 OEU12109.1 - 0.0059 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2802) TPR_7 PF13176.6 OEU12109.1 - 0.047 13.7 0.0 6.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OEU12109.1 - 0.051 13.6 0.1 1.4 9.0 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 GSHPx PF00255.19 OEU12111.1 - 0.019 14.6 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 Glutathione peroxidase Cation_ATPase_C PF00689.21 OEU12112.1 - 1.6e-48 164.9 2.6 4.3e-48 163.4 2.6 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OEU12112.1 - 2e-44 151.3 0.1 2e-44 151.3 0.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OEU12112.1 - 1.3e-18 66.4 1.1 2.8e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OEU12112.1 - 3.4e-18 66.7 0.8 5.3e-17 62.8 0.8 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU12112.1 - 2.1e-16 59.8 0.0 4.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OEU12112.1 - 1.4e-05 25.0 0.5 0.0027 17.5 0.4 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU12112.1 - 6.7e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMEM208_SND2 PF05620.11 OEU12112.1 - 3 7.6 6.9 4.1 7.1 0.1 2.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DDE_Tnp_1_7 PF13843.6 OEU12113.1 - 1.9e-12 47.2 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DNA_pol_phi PF04931.13 OEU12114.1 - 2.4 6.2 8.2 3.2 5.7 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi GRIP PF01465.20 OEU12115.1 - 8.8e-13 48.0 0.5 2e-12 46.8 0.5 1.6 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.9 OEU12115.1 - 0.0024 17.9 14.8 0.0024 17.9 14.8 6.7 2 1 4 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RCC1 PF00415.18 OEU12117.1 - 1.2e-43 147.5 10.2 2.4e-07 31.3 0.1 7.8 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU12117.1 - 3.5e-31 106.3 28.7 1.7e-06 27.7 0.2 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat zf-UBP PF02148.19 OEU12117.1 - 0.063 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein PIG-L PF02585.17 OEU12118.1 - 0.081 13.6 0.0 0.14 12.8 0.0 1.4 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase Siva PF05458.12 OEU12119.1 - 6.1 6.5 31.7 1.2 8.8 20.3 2.3 1 1 1 2 2 2 0 Cd27 binding protein (Siva) UDPGT PF00201.18 OEU12120.1 - 4.4e-14 52.2 0.0 3.4e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Peptidase_S68 PF10461.9 OEU12120.1 - 0.14 12.4 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 Peptidase S68 Methyltransf_25 PF13649.6 OEU12121.1 - 0.0025 18.5 0.0 0.0084 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU12121.1 - 3.2 8.5 0.0 3.2 8.5 0.0 4.9 4 1 0 4 4 4 0 Methyltransferase domain 7tm_1 PF00001.21 OEU12123.1 - 2 7.6 12.4 16 4.7 12.4 2.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Redoxin PF08534.10 OEU12124.1 - 2.5e-08 33.7 0.0 5.7e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Redoxin cobW PF02492.19 OEU12125.1 - 1.7e-47 161.3 0.5 2.7e-47 160.6 0.5 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU12125.1 - 7.4e-07 29.0 0.0 2.9e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OEU12125.1 - 0.002 18.1 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OEU12125.1 - 0.0051 16.9 0.3 2.7 8.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 OEU12125.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 OEU12125.1 - 0.018 15.3 0.0 0.054 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OEU12125.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OEU12125.1 - 0.027 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRPRB PF09439.10 OEU12125.1 - 0.04 13.3 0.1 9.9 5.6 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 OEU12125.1 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OEU12125.1 - 0.11 13.0 0.1 0.67 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU12125.1 - 0.12 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SBDS PF01172.18 OEU12126.1 - 4.2e-09 36.4 0.7 1.1e-08 35.0 0.7 1.8 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ADH_zinc_N_2 PF13602.6 OEU12127.1 - 7.7e-21 75.5 0.0 1.1e-20 75.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OEU12127.1 - 1.4e-09 38.0 0.1 2.7e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SBDS PF01172.18 OEU12128.1 - 1.9e-08 34.3 0.9 4.6e-08 33.0 0.9 1.7 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein zf-MYND PF01753.18 OEU12129.1 - 2.3e-05 24.4 15.7 5.6e-05 23.1 15.7 1.7 1 0 0 1 1 1 1 MYND finger DUF3330 PF11809.8 OEU12129.1 - 2.3 8.3 6.2 5.5 7.1 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Mpv17_PMP22 PF04117.12 OEU12130.1 - 2.4e-05 24.4 0.2 5e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family NESP55 PF06390.12 OEU12130.1 - 0.2 11.2 2.3 0.89 9.1 1.2 2.2 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) BTB PF00651.31 OEU12131.1 - 0.00037 20.7 1.6 0.0076 16.5 0.8 2.8 2 1 0 2 2 2 1 BTB/POZ domain TLD PF07534.16 OEU12133.1 - 2.1e-11 44.2 1.1 2.3e-10 40.9 1.1 2.0 1 1 0 1 1 1 1 TLD ABM PF03992.16 OEU12134.1 - 7.1e-17 61.3 0.1 2.6e-09 37.1 0.0 2.9 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Pkinase PF00069.25 OEU12135.1 - 1.1e-32 113.5 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU12135.1 - 1.1e-26 93.7 0.0 4.1e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OEU12135.1 - 0.036 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU12135.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Nop14 PF04147.12 OEU12136.1 - 3.5 5.7 17.8 4.3 5.4 17.8 1.2 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 OEU12136.1 - 3.8 6.0 16.0 4.2 5.8 16.0 1.0 1 0 0 1 1 1 0 Macoilin family ALMT PF11744.8 OEU12136.1 - 5.4 5.7 7.1 6.7 5.4 7.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ISN1 PF06437.11 OEU12137.1 - 3.1e-98 329.4 0.0 4e-97 325.7 0.0 2.1 1 1 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF2884 PF11101.8 OEU12138.1 - 0.048 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) ABC_tran PF00005.27 OEU12139.1 - 8.1e-45 152.7 0.9 3.3e-23 82.7 0.1 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OEU12139.1 - 1.5e-24 86.7 1.0 6.1e-10 38.9 0.5 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU12139.1 - 6.2e-20 72.2 1.8 0.00035 20.5 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OEU12139.1 - 3.6e-12 46.1 2.8 3.6e-12 46.1 2.8 1.8 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 OEU12139.1 - 1.8e-10 40.4 0.0 0.0009 18.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU12139.1 - 8e-10 39.6 8.1 0.0006 20.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OEU12139.1 - 1.2e-07 31.8 2.7 6.8e-05 22.7 0.5 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 OEU12139.1 - 2e-07 31.2 0.2 0.0033 17.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OEU12139.1 - 2.6e-07 31.2 0.9 0.036 14.5 0.0 2.9 3 1 0 3 3 2 2 AAA ATPase domain NACHT PF05729.12 OEU12139.1 - 5.1e-07 29.8 0.3 0.014 15.3 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 OEU12139.1 - 1.7e-06 28.3 1.4 0.072 13.4 0.1 3.6 3 1 0 3 3 2 2 AAA domain AAA_27 PF13514.6 OEU12139.1 - 2e-05 24.3 0.4 0.33 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OEU12139.1 - 2.2e-05 24.4 0.3 0.3 11.0 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_14 PF13173.6 OEU12139.1 - 2.6e-05 24.3 0.4 0.18 11.9 0.0 3.6 5 0 0 5 5 3 2 AAA domain AAA_28 PF13521.6 OEU12139.1 - 3.6e-05 24.1 0.0 0.47 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OEU12139.1 - 6.5e-05 23.5 0.0 0.075 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OEU12139.1 - 0.00011 21.8 0.1 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 OEU12139.1 - 0.00012 22.5 0.0 0.057 13.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OEU12139.1 - 0.00014 22.2 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 OEU12139.1 - 0.00022 21.0 0.0 0.063 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OEU12139.1 - 0.00032 20.3 0.0 1.5 8.3 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_30 PF13604.6 OEU12139.1 - 0.00034 20.4 0.0 0.33 10.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 OEU12139.1 - 0.00036 19.7 0.1 0.14 11.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.14 OEU12139.1 - 0.00036 20.5 0.2 0.94 9.5 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OEU12139.1 - 0.0004 19.7 0.6 0.09 11.9 0.4 2.3 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OEU12139.1 - 0.00042 20.4 0.0 0.16 12.0 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 OEU12139.1 - 0.00055 19.9 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 OEU12139.1 - 0.00055 20.1 0.2 0.54 10.5 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OEU12139.1 - 0.00095 18.4 0.1 0.083 12.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 OEU12139.1 - 0.0018 18.1 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OEU12139.1 - 0.0029 16.9 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.9 OEU12139.1 - 0.0034 17.1 0.8 3.4 7.4 0.1 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.9 OEU12139.1 - 0.0035 16.3 0.0 0.11 11.4 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 OEU12139.1 - 0.0044 17.0 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 OEU12139.1 - 0.0054 16.7 0.0 4.9 7.0 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain NTPase_1 PF03266.15 OEU12139.1 - 0.0062 16.5 0.1 4 7.3 0.0 2.8 2 0 0 2 2 2 0 NTPase Arf PF00025.21 OEU12139.1 - 0.0063 16.0 0.3 0.3 10.5 0.2 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF815 PF05673.13 OEU12139.1 - 0.0063 15.7 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 OEU12139.1 - 0.0069 15.8 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 OEU12139.1 - 0.0076 15.6 0.0 1.9 7.8 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 OEU12139.1 - 0.0086 15.8 0.1 3.3 7.3 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 OEU12139.1 - 0.011 15.3 0.0 3.9 7.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain FAA_hydro_N_2 PF18288.1 OEU12139.1 - 0.012 16.0 0.4 16 6.0 0.0 4.2 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 HTH_11 PF08279.12 OEU12139.1 - 0.012 15.5 0.1 0.2 11.6 0.0 2.8 3 0 0 3 3 3 0 HTH domain DUF4097 PF13349.6 OEU12139.1 - 0.012 14.9 2.4 0.023 14.0 2.4 1.3 1 0 0 1 1 1 0 Putative adhesin SbcCD_C PF13558.6 OEU12139.1 - 0.018 15.3 0.1 4.3 7.6 0.2 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 OEU12139.1 - 0.031 13.6 0.1 8.1 5.6 0.0 2.4 2 0 0 2 2 2 0 Septin dNK PF01712.19 OEU12139.1 - 0.036 13.9 0.0 2.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Deoxynucleoside kinase SRP54 PF00448.22 OEU12139.1 - 0.04 13.6 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 OEU12139.1 - 0.056 13.5 1.8 4.3 7.4 0.7 3.5 2 1 1 3 3 3 0 Dynamin family MobB PF03205.14 OEU12139.1 - 0.067 13.1 0.1 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 OEU12139.1 - 0.074 12.0 0.1 12 4.8 0.0 3.1 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 OEU12139.1 - 0.093 11.9 0.0 5.7 6.1 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.26 OEU12139.1 - 0.11 12.3 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 OEU12139.1 - 0.11 12.9 0.0 20 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 OEU12139.1 - 0.15 11.9 0.3 1 9.1 0.1 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_13 PF13166.6 OEU12139.1 - 0.16 10.6 3.3 5.9 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 OEU12139.1 - 0.29 11.2 1.9 1.1 9.3 0.0 2.5 3 1 1 4 4 3 0 Helicase HerA, central domain ODV-E18 PF10717.9 OEU12141.1 - 7 6.6 9.3 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 EFTUD2 PF16004.5 OEU12142.1 - 0.071 13.7 0.2 0.071 13.7 0.2 8.2 4 3 1 5 5 5 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus AAA PF00004.29 OEU12144.1 - 5.6e-26 91.5 0.1 6.4e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU12144.1 - 0.0024 17.9 0.0 0.0074 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OEU12144.1 - 0.0045 17.2 0.0 0.0061 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU12144.1 - 0.0092 16.3 3.2 3.2 8.0 1.1 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 OEU12144.1 - 0.048 13.4 0.0 0.17 11.6 0.0 1.9 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OEU12144.1 - 0.053 13.5 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OEU12144.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OEU12144.1 - 0.065 13.8 0.0 0.081 13.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OEU12144.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 OEU12144.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_17 PF13207.6 OEU12144.1 - 0.097 13.1 0.0 0.22 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 OEU12144.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase Cytidylate_kin2 PF13189.6 OEU12144.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_25 PF13481.6 OEU12144.1 - 0.19 11.3 0.6 4.5 6.8 0.0 2.3 2 1 1 3 3 3 0 AAA domain zf-trcl PF13451.6 OEU12145.1 - 3.3e-11 42.9 4.5 9.8e-11 41.4 4.5 1.8 1 0 0 1 1 1 1 Probable zinc-ribbon domain zf-CCCH PF00642.24 OEU12145.1 - 6.6e-07 29.1 4.7 6.6e-07 29.1 4.7 2.8 2 1 1 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OEU12145.1 - 0.00057 19.6 21.1 0.0014 18.4 4.7 3.6 2 1 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OEU12145.1 - 0.0075 16.3 6.6 0.0075 16.3 6.6 3.5 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_2 PF14608.6 OEU12145.1 - 0.013 15.9 14.3 0.14 12.7 5.4 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF1115 PF06544.12 OEU12146.1 - 1.8e-10 41.1 1.2 2.6e-10 40.5 1.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Presenilin PF01080.17 OEU12147.1 - 0.65 8.7 5.6 0.79 8.4 5.6 1.3 1 0 0 1 1 1 0 Presenilin BST2 PF16716.5 OEU12147.1 - 0.76 10.4 11.9 1.1 9.9 7.3 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Endonuclease_7 PF02945.15 OEU12147.1 - 0.79 9.7 8.0 0.062 13.2 2.1 1.9 2 0 0 2 2 2 0 Recombination endonuclease VII DUF3381 PF11861.8 OEU12147.1 - 0.9 9.3 14.7 0.064 13.1 7.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MMU163 PF17119.5 OEU12147.1 - 2.1 7.4 9.7 0.39 9.8 5.3 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Myb_DNA-binding PF00249.31 OEU12148.1 - 2.6e-29 101.1 0.7 5e-09 36.2 0.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU12148.1 - 2.3e-21 75.8 0.8 1.5e-09 38.0 0.1 3.1 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OEU12148.1 - 0.0067 16.4 0.1 0.39 10.7 0.0 2.1 1 1 1 2 2 2 2 SLIDE DUF5357 PF17310.2 OEU12148.1 - 0.011 14.3 0.1 0.016 13.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Myb_DNA-bind_4 PF13837.6 OEU12148.1 - 0.17 12.3 2.3 4.2 7.8 0.1 3.1 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Miga PF10265.9 OEU12150.1 - 0.042 12.8 6.8 0.065 12.2 6.8 1.2 1 0 0 1 1 1 0 Mitoguardin Muted PF14942.6 OEU12150.1 - 0.12 12.8 5.0 0.94 9.8 3.1 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3246 PF11596.8 OEU12151.1 - 0.28 10.6 7.9 0.56 9.6 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Enkurin PF13864.6 OEU12151.1 - 0.47 10.9 9.8 13 6.3 0.8 3.3 3 0 0 3 3 3 0 Calmodulin-binding Herpes_DNAp_acc PF04929.12 OEU12151.1 - 3.2 6.6 5.9 3.7 6.4 5.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Fer2 PF00111.27 OEU12152.1 - 1.4e-10 41.0 0.5 1.9e-10 40.5 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rotamase PF00639.21 OEU12153.1 - 2.8e-14 53.9 0.0 2.9e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OEU12153.1 - 1.1e-09 38.9 0.0 1.2e-09 38.7 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU12153.1 - 0.14 13.0 0.0 0.14 13.0 0.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Secretin_N_2 PF07655.13 OEU12154.1 - 3.8 8.1 11.9 1.1 9.8 6.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain HSF_DNA-bind PF00447.17 OEU12155.1 - 4.2e-14 52.9 0.0 6.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding 2OG-FeII_Oxy_3 PF13640.6 OEU12156.1 - 2.9e-15 56.9 0.4 3.1e-14 53.6 0.4 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU12156.1 - 3.3e-10 40.5 0.1 0.0014 19.2 0.1 2.6 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OEU12156.1 - 0.0034 17.8 0.1 0.016 15.6 0.0 2.3 2 1 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy PF03171.20 OEU12156.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PseudoU_synth_2 PF00849.22 OEU12158.1 - 2.2e-25 89.6 0.0 8.2e-25 87.7 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase SGL PF08450.12 OEU12159.1 - 1.3e-45 155.9 0.0 1.7e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 OEU12159.1 - 7.1e-05 22.6 0.1 0.00046 20.0 0.0 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Str_synth PF03088.16 OEU12159.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 2 0 0 2 2 2 0 Strictosidine synthase Reg_prop PF07494.11 OEU12159.1 - 0.11 12.8 0.2 46 4.7 0.1 3.8 3 0 0 3 3 3 0 Two component regulator propeller TIM PF00121.18 OEU12160.1 - 3.3e-78 262.4 0.1 5.1e-78 261.8 0.1 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase WD40 PF00400.32 OEU12162.1 - 1.2e-07 32.3 3.4 0.00039 21.2 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU12162.1 - 7.3e-05 23.0 0.0 0.3 11.4 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 OEU12163.1 - 1.1e-07 31.4 2.7 0.0017 18.1 1.3 2.3 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU12163.1 - 2e-05 24.9 6.0 0.00035 20.9 2.1 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU12163.1 - 0.0015 18.8 0.1 0.085 13.5 0.1 3.3 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 OEU12163.1 - 0.084 13.0 2.6 0.35 11.0 0.5 2.7 3 0 0 3 3 3 0 Leucine Rich repeat PsbQ PF05757.11 OEU12164.1 - 0.22 11.2 1.8 3.7 7.2 0.3 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) PA PF02225.22 OEU12165.1 - 4.1e-09 36.3 0.0 9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF4079 PF13301.6 OEU12165.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) mono-CXXC PF15626.6 OEU12165.1 - 0.44 10.9 3.1 0.83 10.1 3.1 1.4 1 0 0 1 1 1 0 single CXXC unit LRR_8 PF13855.6 OEU12166.1 - 4e-09 36.1 5.7 0.00042 20.0 1.1 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OEU12166.1 - 2e-06 28.0 9.5 0.0052 17.2 0.1 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU12166.1 - 0.014 15.8 2.2 91 4.2 0.0 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat DUF1674 PF07896.12 OEU12167.1 - 1.3e-10 41.6 4.4 2.6e-10 40.6 4.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) FHA PF00498.26 OEU12168.1 - 3.3e-14 53.0 0.2 5.8e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OEU12168.1 - 2.6e-05 24.4 0.0 5.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LSPR PF06049.12 OEU12168.1 - 1.9 8.7 4.9 25 5.3 0.8 3.4 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat Phage_stabilise PF11134.8 OEU12169.1 - 0.0032 16.4 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Phage stabilisation protein Bac_chlorC PF02043.17 OEU12169.1 - 0.0058 16.6 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 Bacteriochlorophyll C binding protein DNA_pol3_beta PF00712.19 OEU12169.1 - 0.078 13.1 1.4 0.76 9.9 0.4 2.2 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain PIP5K PF01504.18 OEU12169.1 - 0.12 11.6 1.7 0.2 10.9 1.7 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase APG6_N PF17675.1 OEU12169.1 - 0.16 12.5 11.0 0.27 11.8 11.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4174 PF13778.6 OEU12169.1 - 0.24 11.9 5.3 0.27 11.7 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) RRM_3 PF08777.11 OEU12169.1 - 0.85 9.7 5.3 0.4 10.7 2.2 1.9 1 1 0 1 1 1 0 RNA binding motif FTZ PF03867.14 OEU12169.1 - 2.5 7.6 6.4 3.6 7.0 6.4 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CENP-B_dimeris PF09026.10 OEU12170.1 - 0.96 9.9 16.7 5.2 7.5 15.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 OEU12170.1 - 1.1 9.5 9.7 1.9 8.8 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 OEU12170.1 - 2 8.4 4.8 0.56 10.2 1.5 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2457 PF10446.9 OEU12170.1 - 2.6 7.1 14.3 5.3 6.1 14.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 OEU12170.1 - 3.7 5.6 5.3 6.1 4.9 5.3 1.2 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 OEU12170.1 - 5.5 5.9 5.0 8.3 5.4 5.0 1.2 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 OEU12170.1 - 7.7 5.8 8.6 0.93 8.9 3.8 1.7 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.25 OEU12171.1 - 1.9e-56 191.4 0.0 3.2e-34 118.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU12171.1 - 1.6e-28 99.7 0.0 9.6e-22 77.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OEU12171.1 - 0.00028 20.0 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OEU12171.1 - 0.015 14.9 0.3 0.027 14.1 0.3 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OEU12171.1 - 0.11 12.4 0.1 0.46 10.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OEU12171.1 - 0.18 11.1 0.3 0.62 9.4 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_3 PF07859.13 OEU12172.1 - 1.2e-13 51.4 0.0 1.2e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 OEU12173.1 - 1.2e-13 51.1 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU12173.1 - 1.7e-10 40.3 0.0 2.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OEU12173.1 - 0.00065 19.1 0.0 0.0023 17.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU12173.1 - 0.00094 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU12173.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PPR_2 PF13041.6 OEU12174.1 - 4.6e-17 61.9 6.4 0.016 15.4 0.0 8.6 6 4 3 9 9 9 6 PPR repeat family PPR_3 PF13812.6 OEU12174.1 - 2.1e-11 43.7 1.5 0.024 14.7 0.1 6.9 4 3 3 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU12174.1 - 1.4e-10 40.7 8.9 1.1 9.1 0.0 9.7 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 OEU12174.1 - 3.7e-10 39.5 0.1 0.58 9.5 0.0 5.1 2 1 3 6 6 6 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OEU12174.1 - 2.2e-08 33.8 15.8 6.1 7.3 0.0 10.5 9 3 0 9 9 9 2 PPR repeat Wzy_C_2 PF11846.8 OEU12174.1 - 0.00015 21.8 0.0 0.0079 16.1 0.0 3.3 2 1 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal TPR_19 PF14559.6 OEU12174.1 - 0.0084 16.6 2.5 0.11 13.0 0.1 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU12174.1 - 0.095 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 OEU12174.1 - 0.93 10.3 4.5 38 5.2 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ubiquitin PF00240.23 OEU12175.1 - 1.9e-13 49.9 0.0 1.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 OEU12175.1 - 0.0085 16.5 0.0 4.3 7.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain UN_NPL4 PF11543.8 OEU12175.1 - 0.029 14.8 0.0 6.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Rad60-SLD PF11976.8 OEU12175.1 - 0.034 14.0 0.0 2.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like USP7_C2 PF14533.6 OEU12175.1 - 0.081 12.6 0.0 2.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal HSF_DNA-bind PF00447.17 OEU12177.1 - 1.1e-14 54.8 0.7 1.1e-14 54.7 0.7 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2722 PF10846.8 OEU12179.1 - 0.00086 18.4 1.4 0.00086 18.4 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 OEU12179.1 - 0.67 9.5 12.7 0.91 9.1 12.7 1.1 1 0 0 1 1 1 0 Spt20 family RNase_H2_suC PF08615.11 OEU12179.1 - 0.69 10.1 4.0 1.2 9.2 4.0 1.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Med3 PF11593.8 OEU12179.1 - 9.1 5.3 10.4 11 5.0 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAR2 PF05282.11 OEU12180.1 - 2.5e-22 79.8 5.6 7.1e-22 78.3 5.6 1.7 1 1 0 1 1 1 1 AAR2 protein BUD22 PF09073.10 OEU12180.1 - 0.98 8.7 5.4 1.8 7.8 1.3 2.3 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.25 OEU12181.1 - 2.2e-61 207.6 0.0 2.5e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU12181.1 - 2.1e-22 79.7 0.0 3.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU12181.1 - 1.1e-05 24.9 0.0 0.01 15.2 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 OEU12181.1 - 0.00026 21.0 0.1 0.0017 18.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU12181.1 - 0.00037 19.9 0.1 0.0006 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OEU12181.1 - 0.0045 16.6 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Tnp_DNA_bind PF14706.6 OEU12181.1 - 0.051 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Transposase DNA-binding FTA2 PF13095.6 OEU12181.1 - 0.099 12.2 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cnd1 PF12717.7 OEU12181.1 - 0.12 12.5 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PTB PF08416.13 OEU12181.1 - 0.16 12.1 0.2 1.2e+02 2.8 0.0 3.0 3 0 0 3 3 3 0 Phosphotyrosine-binding domain Tektin PF03148.14 OEU12183.1 - 0.18 10.5 0.1 0.24 10.1 0.1 1.1 1 0 0 1 1 1 0 Tektin family Endomucin PF07010.12 OEU12183.1 - 2 8.3 9.3 2.3 8.1 9.3 1.0 1 0 0 1 1 1 0 Endomucin Afaf PF15339.6 OEU12184.1 - 0.01 15.6 0.9 0.01 15.6 0.9 1.1 1 0 0 1 1 1 1 Acrosome formation-associated factor SGIII PF15467.6 OEU12184.1 - 0.021 14.1 1.9 0.024 13.9 1.9 1.0 1 0 0 1 1 1 0 Secretogranin-3 Folliculin PF11704.8 OEU12184.1 - 0.033 14.1 1.1 0.037 13.9 1.1 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Menin PF05053.13 OEU12184.1 - 0.089 11.1 1.9 0.089 11.1 1.9 1.1 1 0 0 1 1 1 0 Menin REC114-like PF15165.6 OEU12184.1 - 0.099 12.4 1.3 0.12 12.1 1.3 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like HSF_DNA-bind PF00447.17 OEU12185.1 - 4.4e-21 75.3 1.7 4.9e-21 75.1 1.7 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DUF572 PF04502.13 OEU12186.1 - 3.8 7.0 33.2 5.9 6.4 33.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Methyltransf_16 PF10294.9 OEU12187.1 - 3.3e-13 49.7 0.9 5.5e-12 45.8 0.9 2.2 1 1 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 OEU12187.1 - 0.058 13.1 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SR-25 PF10500.9 OEU12187.1 - 0.098 12.3 1.3 0.14 11.7 1.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OEU12187.1 - 5.9 7.6 7.4 12 6.7 7.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Nop14 PF04147.12 OEU12189.1 - 0.13 10.5 3.2 0.18 10.0 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family HA PF03457.14 OEU12190.1 - 5e-33 113.2 3.5 3.5e-16 59.3 0.2 2.0 2 0 0 2 2 2 2 Helicase associated domain ATP-synt_E_2 PF08112.11 OEU12190.1 - 0.00086 19.5 3.6 0.24 11.7 0.1 2.3 2 0 0 2 2 2 2 ATP synthase epsilon subunit WHEP-TRS PF00458.20 OEU12190.1 - 0.024 14.8 0.9 7.2 6.8 0.1 2.3 2 0 0 2 2 2 0 WHEP-TRS domain DUF4817 PF16087.5 OEU12190.1 - 0.068 13.0 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) SNase PF00565.17 OEU12191.1 - 7.2e-09 36.1 0.1 1.4e-08 35.1 0.0 1.5 2 0 0 2 2 2 1 Staphylococcal nuclease homologue LVIVD PF08309.11 OEU12192.1 - 3.3e-05 23.1 0.1 0.029 13.7 0.0 3.5 3 0 0 3 3 3 2 LVIVD repeat Beta_propel PF09826.9 OEU12192.1 - 0.00017 20.6 0.1 0.022 13.6 0.1 2.4 1 1 1 2 2 2 2 Beta propeller domain CCDC53 PF10152.9 OEU12192.1 - 0.24 11.8 0.9 0.51 10.7 0.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 OEU12192.1 - 4.5 7.2 7.6 7.6 6.5 7.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SF3A2 PF16835.5 OEU12193.1 - 7.5e-34 116.0 1.6 1.7e-33 114.8 0.1 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OEU12193.1 - 3e-07 30.6 1.8 7.2e-07 29.4 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type FAM222A PF15258.6 OEU12193.1 - 0.018 14.2 1.4 0.03 13.5 1.4 1.3 1 0 0 1 1 1 0 Protein family of FAM222A DUF5358 PF17311.2 OEU12193.1 - 0.11 12.5 3.4 0.14 12.1 1.8 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5358) TMEM51 PF15345.6 OEU12194.1 - 0.019 14.8 0.3 0.019 14.8 0.3 3.0 3 0 0 3 3 3 0 Transmembrane protein 51 BRO1 PF03097.18 OEU12195.1 - 2.4e-50 171.5 0.7 2.9e-50 171.2 0.7 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF4252 PF14060.6 OEU12195.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) CorA PF01544.18 OEU12195.1 - 0.12 11.7 1.1 0.27 10.5 0.3 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein L27_1 PF09058.10 OEU12196.1 - 0.019 14.9 1.9 0.69 9.9 0.0 3.6 4 0 0 4 4 4 0 L27_1 HEAT PF02985.22 OEU12196.1 - 0.32 11.4 13.0 5.8 7.5 0.0 7.0 8 0 0 8 8 8 0 HEAT repeat Glyoxalase PF00903.25 OEU12197.1 - 4.4e-06 26.9 0.0 6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OEU12197.1 - 2e-05 25.3 0.0 2.8e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OEU12197.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Abhydrolase_1 PF00561.20 OEU12198.1 - 2.2e-20 73.4 0.0 4.6e-20 72.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU12198.1 - 6.1e-15 55.1 0.0 5.5e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU12198.1 - 8.5e-05 23.3 0.0 0.00013 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OEU12198.1 - 0.00032 19.5 0.0 0.00049 18.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 OEU12198.1 - 0.0048 16.4 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 OEU12198.1 - 0.0051 16.5 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 OEU12198.1 - 0.014 14.9 0.0 0.8 9.2 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family zf-RING_2 PF13639.6 OEU12199.1 - 1.5e-08 34.8 5.2 2.5e-08 34.1 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU12199.1 - 2.4e-05 24.0 5.7 4.6e-05 23.1 5.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 OEU12199.1 - 5.3e-05 23.3 3.3 0.00011 22.3 3.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain Mucin PF01456.17 OEU12199.1 - 0.00011 22.2 17.2 0.11 12.5 0.0 3.3 3 0 0 3 3 3 2 Mucin-like glycoprotein zf-RING_UBOX PF13445.6 OEU12199.1 - 0.0017 18.4 0.8 0.0054 16.7 0.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OEU12199.1 - 0.0032 17.7 3.8 0.0083 16.4 3.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU12199.1 - 0.0083 16.0 5.4 0.018 14.9 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU12199.1 - 0.051 13.6 3.7 0.26 11.4 3.9 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OEU12199.1 - 0.068 13.1 3.6 0.39 10.7 0.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 OEU12199.1 - 0.12 12.0 2.5 0.24 11.1 2.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU12199.1 - 0.15 12.0 6.7 0.42 10.5 6.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU12199.1 - 0.37 10.8 6.1 0.89 9.6 6.1 1.7 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 OEU12199.1 - 1.2 9.1 6.8 2.2 8.2 6.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 OEU12199.1 - 2.6 8.0 11.1 19 5.2 11.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TAXi_N PF14543.6 OEU12199.1 - 2.6 8.3 7.2 10 6.3 7.2 2.1 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal zf-C3H2C3 PF17122.5 OEU12199.1 - 5.4 7.2 7.1 0.64 10.1 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger CRAL_TRIO PF00650.20 OEU12200.1 - 0.0036 17.0 0.0 0.014 15.1 0.0 2.0 1 1 1 2 2 2 1 CRAL/TRIO domain MGC-24 PF05283.11 OEU12200.1 - 8.6 6.8 11.5 34 4.9 8.9 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin His_Phos_1 PF00300.22 OEU12203.1 - 8.4e-08 32.1 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OEU12203.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Orn_Arg_deC_N PF02784.16 OEU12205.1 - 1.1e-32 113.3 0.0 1.6e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OEU12205.1 - 4.3e-13 49.3 0.0 5.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF2740 PF10872.8 OEU12205.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Histone PF00125.24 OEU12207.1 - 5.3e-54 182.1 1.0 5.9e-54 182.0 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OEU12207.1 - 0.00017 22.2 1.1 0.0002 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OEU12207.1 - 0.00076 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU12207.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OEU12207.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OEU12207.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 OEU12208.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU12208.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OEU12208.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OEU12208.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU12208.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OEU12208.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OEU12208.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OEU12208.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 OEU12209.1 - 3.8e-20 71.3 2.2 7.1e-20 70.4 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OEU12209.1 - 1.1e-14 54.9 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OEU12209.1 - 0.00054 20.2 0.0 0.00071 19.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU12210.1 - 4.8e-20 72.2 0.6 5.9e-20 72.0 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OEU12210.1 - 0.00029 21.3 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 OEU12210.1 - 0.0025 17.9 0.2 0.003 17.6 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CBFD_NFYB_HMF PF00808.23 OEU12210.1 - 0.0049 17.1 1.2 0.0055 17.0 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DRMBL PF07522.14 OEU12211.1 - 0.079 13.2 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase YfhO PF09586.10 OEU12212.1 - 0.13 10.4 2.3 0.21 9.8 2.3 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3291 PF11695.8 OEU12213.1 - 0.009 15.7 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) FAM176 PF14851.6 OEU12213.1 - 0.018 14.7 0.2 0.018 14.7 0.2 2.3 2 1 0 2 2 2 0 FAM176 family Mem_trans PF03547.18 OEU12213.1 - 0.098 11.0 0.8 0.16 10.3 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF3824 PF12868.7 OEU12213.1 - 0.19 12.4 5.0 0.56 10.9 5.0 1.9 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) TMEM51 PF15345.6 OEU12213.1 - 2.2 8.0 8.8 5.2 6.8 8.6 1.7 1 1 1 2 2 2 0 Transmembrane protein 51 HMG_box PF00505.19 OEU12214.1 - 2.4e-06 27.9 1.7 2.4e-06 27.9 1.7 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU12214.1 - 4.7e-05 23.9 1.0 0.00013 22.5 1.0 1.8 1 0 0 1 1 1 1 HMG-box domain DNA_pol_phi PF04931.13 OEU12214.1 - 1.7 6.6 6.6 2.3 6.2 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Disaggr_repeat PF06848.11 OEU12215.1 - 0.11 12.2 0.8 0.2 11.3 0.8 1.4 1 0 0 1 1 1 0 Disaggregatase related repeat Gram_pos_anchor PF00746.21 OEU12215.1 - 4 7.5 5.0 0.6 10.1 0.8 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF1995 PF09353.10 OEU12216.1 - 7.2e-29 101.2 0.0 1.1e-28 100.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Pyrophosphatase PF00719.19 OEU12217.1 - 1.4e-48 164.7 1.0 1.7e-48 164.5 1.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase TMEM51 PF15345.6 OEU12218.1 - 0.013 15.4 0.0 0.013 15.4 0.0 2.4 2 1 0 2 2 2 0 Transmembrane protein 51 zf-C3HC4_3 PF13920.6 OEU12219.1 - 1.1e-06 28.4 13.7 1.1e-06 28.4 13.7 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 OEU12219.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU12219.1 - 0.0003 21.0 0.0 0.00069 19.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 OEU12219.1 - 0.0006 19.6 6.8 0.0006 19.6 6.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Ank PF00023.30 OEU12219.1 - 0.00071 19.9 0.0 0.09 13.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat zf-C3HC4 PF00097.25 OEU12219.1 - 0.00074 19.3 7.7 0.00074 19.3 7.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU12219.1 - 0.0021 18.4 7.6 0.0021 18.4 7.6 3.3 3 1 0 3 3 3 1 Ring finger domain zf-RanBP PF00641.18 OEU12219.1 - 0.0027 17.0 3.1 0.0027 17.0 3.1 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.6 OEU12219.1 - 0.0037 17.1 4.8 0.017 15.0 4.8 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU12219.1 - 0.085 12.6 2.7 0.24 11.2 2.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OEU12219.1 - 0.28 11.4 4.4 1.6 9.0 4.4 2.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OEU12219.1 - 1 9.4 6.7 3.5 7.7 6.7 2.1 1 0 0 1 1 1 0 RING-type zinc-finger NAD_binding_10 PF13460.6 OEU12220.1 - 3.8e-15 56.3 0.4 5.8e-11 42.6 0.4 3.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU12220.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OEU12220.1 - 6.2e-05 22.6 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OEU12220.1 - 0.00036 20.6 0.1 0.00063 19.9 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OEU12220.1 - 0.0008 19.8 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OEU12220.1 - 0.0014 17.8 0.2 0.0024 17.1 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 OEU12220.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OEU12220.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 OEU12220.1 - 0.012 15.7 0.2 0.016 15.2 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 OEU12220.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cwf_Cwc_15 PF04889.12 OEU12221.1 - 10 5.8 7.5 12 5.6 7.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BT1 PF03092.16 OEU12222.1 - 2e-91 306.8 9.5 4.6e-50 170.3 1.9 3.1 1 1 1 2 2 2 2 BT1 family PUCC PF03209.15 OEU12222.1 - 0.00026 20.1 1.5 0.00059 19.0 0.2 2.0 2 0 0 2 2 2 1 PUCC protein ATP-synt_ab PF00006.25 OEU12223.1 - 5.2e-73 245.2 0.0 8e-73 244.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OEU12223.1 - 5.1e-42 143.2 0.2 7.5e-42 142.6 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OEU12223.1 - 5.3e-17 62.1 2.1 1.1e-16 61.0 2.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 OEU12223.1 - 0.0016 18.5 0.7 0.0037 17.4 0.7 1.6 1 0 0 1 1 1 1 HAS barrel domain ATPase PF06745.13 OEU12223.1 - 0.16 11.3 0.1 0.31 10.3 0.1 1.4 1 0 0 1 1 1 0 KaiC TMEM52 PF14979.6 OEU12224.1 - 0.06 13.3 0.8 0.19 11.6 0.8 1.8 1 0 0 1 1 1 0 Transmembrane 52 GRP PF07172.11 OEU12224.1 - 0.4 11.4 10.0 3.1 8.6 10.0 2.6 1 0 0 1 1 1 0 Glycine rich protein family Abhydrolase_5 PF12695.7 OEU12226.1 - 2.6e-23 82.6 0.0 3.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU12226.1 - 0.21 10.8 0.0 0.6 9.3 0.0 1.6 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF21 PF01595.20 OEU12227.1 - 0.056 13.1 5.7 1 9.0 0.1 2.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Peptidase_M17 PF00883.21 OEU12228.1 - 1.8e-20 73.4 0.0 2e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain HA PF03457.14 OEU12229.1 - 5.1e-28 97.2 0.1 6.5e-15 55.2 0.2 2.1 2 0 0 2 2 2 2 Helicase associated domain HIP1_clath_bdg PF16515.5 OEU12230.1 - 0.012 16.2 3.0 0.012 16.2 3.0 5.5 4 1 0 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-Tim10_DDP PF02953.15 OEU12231.1 - 2.5e-19 68.7 2.5 3e-19 68.4 2.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2368 PF10166.9 OEU12231.1 - 0.059 13.0 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Cu_amine_oxid PF01179.20 OEU12233.1 - 3.9e-79 266.5 0.1 5.3e-79 266.0 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OEU12233.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain CRAL_TRIO PF00650.20 OEU12234.1 - 1.5e-22 80.1 0.0 2.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU12234.1 - 1.2e-15 57.8 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Meckelin PF09773.9 OEU12236.1 - 0.056 11.5 0.8 0.067 11.3 0.8 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) ETRAMP PF09716.10 OEU12236.1 - 2.2 8.4 6.1 0.17 11.9 1.1 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TRP PF06011.12 OEU12236.1 - 5.8 5.5 12.7 1.4 7.6 2.6 2.0 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Rotamase_3 PF13616.6 OEU12237.1 - 3.2e-16 59.9 0.1 1.2e-15 58.1 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OEU12237.1 - 4.6e-16 59.6 0.0 8.3e-16 58.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU12237.1 - 0.00038 21.3 0.0 0.00058 20.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain EamA PF00892.20 OEU12238.1 - 1.3e-22 80.4 36.2 1.1e-13 51.6 8.8 3.1 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU12238.1 - 0.0018 17.7 10.8 0.2 11.0 0.1 2.7 2 2 0 2 2 2 2 Triose-phosphate Transporter family DUF2583 PF10762.9 OEU12238.1 - 1.9 8.9 4.8 1.2 9.6 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DUF3439 PF11921.8 OEU12238.1 - 7.4 6.6 9.4 15 5.6 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF202 PF02656.15 OEU12238.1 - 7.6 7.1 26.3 0.24 11.9 1.4 5.4 5 1 0 5 5 5 0 Domain of unknown function (DUF202) DUF4611 PF15387.6 OEU12239.1 - 0.0067 16.6 1.4 0.0067 16.6 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) LRR_4 PF12799.7 OEU12239.1 - 0.075 13.5 17.2 3.4 8.2 0.4 6.6 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF5406 PF17400.2 OEU12239.1 - 0.86 10.0 6.3 14 6.1 0.7 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5406) FAM176 PF14851.6 OEU12239.1 - 2.3 7.9 8.9 0.52 10.0 3.7 2.3 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 OEU12239.1 - 5.7 6.8 12.2 0.16 11.8 4.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region TFB6 PF17110.5 OEU12239.1 - 6 6.6 7.3 4.6 7.0 0.9 3.1 2 1 1 3 3 3 0 Subunit 11 of the general transcription factor TFIIH Peroxidase_ext PF11895.8 OEU12240.1 - 3.1 7.8 7.1 1.5 8.8 0.2 2.9 2 1 0 2 2 2 0 Fungal peroxidase extension region Mucin PF01456.17 OEU12240.1 - 5.4 7.0 19.4 2.8 7.9 16.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Reprolysin_5 PF13688.6 OEU12242.1 - 0.00046 20.4 0.1 0.00095 19.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 OEU12242.1 - 0.02 14.8 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 OEU12242.1 - 0.031 13.2 0.1 0.064 12.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 OEU12242.1 - 0.078 11.6 0.1 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 OEU12242.1 - 0.08 13.5 2.5 0.082 13.4 0.0 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 OEU12242.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 DnaJ PF00226.31 OEU12243.1 - 0.0001 22.4 0.2 0.00044 20.3 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain PT PF04886.12 OEU12243.1 - 0.00031 20.2 8.9 0.00088 18.8 8.9 1.8 1 0 0 1 1 1 1 PT repeat SMN PF06003.12 OEU12243.1 - 0.0025 17.1 0.2 0.0025 17.1 0.2 3.8 4 1 0 4 4 4 1 Survival motor neuron protein (SMN) Fasciclin PF02469.22 OEU12243.1 - 0.0052 17.0 0.1 0.24 11.6 0.1 3.2 1 1 0 1 1 1 1 Fasciclin domain Tudor_3 PF18115.1 OEU12243.1 - 0.016 15.1 0.2 0.055 13.3 0.1 1.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain PHD PF00628.29 OEU12243.1 - 0.84 9.6 4.2 2 8.4 4.2 1.6 1 0 0 1 1 1 0 PHD-finger MLVIN_C PF18697.1 OEU12244.1 - 0.081 13.0 0.1 15 5.8 0.0 2.2 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain TBCC_N PF16752.5 OEU12245.1 - 0.0082 16.6 14.1 5.9 7.4 0.0 5.1 5 0 0 5 5 5 3 Tubulin-specific chaperone C N-terminal domain ALC PF17527.2 OEU12245.1 - 0.011 15.4 3.6 9.2 5.9 0.0 3.7 3 0 0 3 3 3 0 Phage ALC protein DUF3037 PF11236.8 OEU12245.1 - 0.069 13.6 0.0 1e+02 3.4 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) Imm70 PF15601.6 OEU12245.1 - 3.2 7.3 7.8 0.62 9.6 0.1 3.3 4 1 1 5 5 5 0 Immunity protein 70 PDZ_6 PF17820.1 OEU12246.1 - 0.0092 15.8 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 PDZ domain zf-Di19 PF05605.12 OEU12246.1 - 0.98 9.8 4.4 1.1 9.7 2.2 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4436 PF14494.6 OEU12247.1 - 0.022 14.1 4.0 0.067 12.5 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4436) zf-Di19 PF05605.12 OEU12247.1 - 0.044 14.1 0.2 0.092 13.0 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding T2SS_PulS_OutS PF09691.10 OEU12247.1 - 0.058 13.6 0.1 0.058 13.6 0.1 2.9 3 0 0 3 3 3 0 Type II secretion system pilotin lipoprotein (PulS_OutS) HrpF PF06266.12 OEU12247.1 - 0.062 13.6 1.2 0.18 12.1 0.2 2.2 2 0 0 2 2 2 0 HrpF protein zf-C2H2_4 PF13894.6 OEU12247.1 - 0.19 12.7 1.0 0.42 11.6 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger HA PF03457.14 OEU12248.1 - 5.6e-29 100.3 0.5 4.4e-13 49.4 0.1 2.5 3 0 0 3 3 3 2 Helicase associated domain Bac_DNA_binding PF00216.21 OEU12248.1 - 0.077 13.2 0.3 3.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial DNA-binding protein PBCV_basic_adap PF08789.10 OEU12249.1 - 0.55 10.4 2.3 1.5 9.0 0.7 2.1 1 1 1 2 2 2 0 PBCV-specific basic adaptor domain P5CR_dimer PF14748.6 OEU12250.1 - 3.4e-34 117.2 0.2 8.9e-34 115.8 0.0 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OEU12250.1 - 4.6e-15 56.0 0.0 8.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OEU12250.1 - 2.9e-09 37.3 0.0 5.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 OEU12250.1 - 0.00023 21.5 0.0 0.00046 20.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Shikimate_DH PF01488.20 OEU12250.1 - 0.00042 20.4 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OEU12250.1 - 0.0058 16.0 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 OEU12250.1 - 0.0087 15.0 0.1 0.024 13.6 0.0 1.6 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 OEU12250.1 - 0.027 15.3 0.0 0.053 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 OEU12250.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DpaA_N PF16924.5 OEU12250.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain DUF364 PF04016.12 OEU12250.1 - 0.22 11.1 1.1 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative heavy-metal chelation Cyt-b5 PF00173.28 OEU12251.1 - 2e-18 66.3 0.4 3.7e-18 65.4 0.4 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MHB PF16525.5 OEU12251.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Haemophore, haem-binding Peptidase_M17 PF00883.21 OEU12252.1 - 2.7e-95 319.2 0.1 3.2e-95 319.0 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain SET PF00856.28 OEU12254.1 - 5.1e-09 36.7 0.0 4.6e-07 30.4 0.0 2.9 2 1 0 2 2 2 1 SET domain PepX_C PF08530.10 OEU12254.1 - 0.012 15.6 0.2 0.69 9.8 0.2 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Bestrophin PF01062.21 OEU12255.1 - 8e-23 81.3 0.3 1.4e-22 80.5 0.3 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RPN13_C PF16550.5 OEU12257.1 - 1.3e-18 67.2 1.8 6.5e-18 64.9 0.7 2.2 2 0 0 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 OEU12257.1 - 6.1e-05 23.5 0.4 0.0001 22.7 0.4 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF892 PF05974.12 OEU12257.1 - 0.031 14.3 0.2 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Spidroin_MaSp PF11260.8 OEU12257.1 - 0.23 11.8 2.9 0.94 9.8 0.0 2.5 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 EF-hand_7 PF13499.6 OEU12258.1 - 1.6e-06 28.5 0.0 1.8e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair SUB1_ProdP9 PF18213.1 OEU12258.1 - 0.0027 17.5 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 EF-hand_6 PF13405.6 OEU12258.1 - 0.013 15.4 0.1 0.51 10.4 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 OEU12258.1 - 0.016 15.1 0.2 0.088 12.7 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 OEU12258.1 - 0.047 13.2 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 EF hand RNase_PH_C PF03725.15 OEU12258.1 - 0.079 13.0 0.8 0.19 11.8 0.8 1.9 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 O-FucT PF10250.9 OEU12260.1 - 2.2e-47 162.4 0.0 2.7e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF957 PF06117.11 OEU12260.1 - 0.6 9.7 3.1 0.31 10.6 0.3 1.9 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) Proteasome PF00227.26 OEU12261.1 - 3.4e-59 199.5 0.0 3.9e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU12261.1 - 2.3e-10 39.9 0.3 3.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-FPG_IleRS PF06827.14 OEU12262.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Redoxin PF08534.10 OEU12262.1 - 0.039 13.7 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 OEU12262.1 - 0.069 13.4 0.2 0.097 12.9 0.1 1.5 2 0 0 2 2 2 0 Glutaredoxin YukC PF10140.9 OEU12262.1 - 0.084 11.7 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC HSP70 PF00012.20 OEU12263.1 - 2.7e-87 293.4 17.3 6.5e-87 292.1 5.2 3.9 1 1 3 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 OEU12263.1 - 3.4e-06 26.1 0.0 5.2e-05 22.2 0.0 2.6 3 0 0 3 3 3 1 MreB/Mbl protein RNase_PH PF01138.21 OEU12264.1 - 3.6e-10 40.4 0.0 7.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OEU12264.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 O-FucT PF10250.9 OEU12265.1 - 6.5e-19 68.8 0.0 1e-18 68.2 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ank_2 PF12796.7 OEU12267.1 - 3.3e-22 78.9 0.5 0.017 15.7 0.0 8.3 5 3 3 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.30 OEU12267.1 - 5.6e-13 48.7 3.8 3.5 8.2 0.0 9.4 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 OEU12267.1 - 2.8e-11 43.4 2.3 1.6 9.1 0.0 8.7 8 0 0 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU12267.1 - 7.4e-10 38.2 3.0 7.8 7.4 0.0 9.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 OEU12267.1 - 5.2e-08 33.3 8.4 1.2 9.8 0.0 8.3 7 2 2 9 9 9 2 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OEU12267.1 - 2e-06 27.3 0.0 2.6e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OEU12267.1 - 8.9e-06 25.2 0.2 0.0014 18.0 0.4 2.6 2 0 0 2 2 2 2 Protein kinase domain SepRS_C PF18006.1 OEU12269.1 - 0.034 14.2 0.0 21 5.3 0.0 3.1 2 0 0 2 2 2 0 O-phosphoseryl-tRNA synthetase C-terminal domain HMG_box PF00505.19 OEU12270.1 - 4.7e-13 49.4 0.8 1e-06 29.1 0.5 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU12270.1 - 1.9e-09 38.0 1.1 0.00016 22.2 0.3 2.4 2 0 0 2 2 2 2 HMG-box domain AvrM_N PF18247.1 OEU12270.1 - 0.03 14.3 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain YABBY PF04690.13 OEU12270.1 - 0.12 13.0 0.7 0.12 13.0 0.7 1.7 1 1 1 2 2 2 0 YABBY protein MFS_1 PF07690.16 OEU12271.1 - 1.9e-17 63.2 15.9 1.9e-17 63.2 15.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Adeno_E1B_55K_N PF04623.12 OEU12273.1 - 7.6 7.3 6.0 46 4.8 0.1 3.2 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus PCNA_C PF02747.15 OEU12274.1 - 3.6e-46 156.5 0.0 7.6e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 OEU12274.1 - 7.6e-40 135.6 2.4 1.6e-39 134.5 1.4 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Hus1 PF04005.12 OEU12274.1 - 0.00023 20.4 0.1 0.0041 16.3 0.0 2.1 2 0 0 2 2 2 1 Hus1-like protein Rad1 PF02144.16 OEU12274.1 - 0.00051 19.2 0.1 0.004 16.3 0.1 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OEU12274.1 - 0.0023 17.4 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Cthe_2159 PF14262.6 OEU12274.1 - 0.095 12.0 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate-binding domain-containing protein Cthe_2159 Ribosomal_S21e PF01249.18 OEU12275.1 - 6.5e-34 115.9 0.1 7.4e-34 115.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e ProRS-C_1 PF09180.11 OEU12276.1 - 5.3e-24 84.2 1.1 1.4e-23 82.9 1.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OEU12276.1 - 1.6e-23 83.6 0.0 2.5e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OEU12276.1 - 3.2e-19 68.9 0.0 6.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Rubrerythrin PF02915.17 OEU12276.1 - 0.15 12.4 0.7 5 7.5 0.8 2.2 2 0 0 2 2 2 0 Rubrerythrin DUF4079 PF13301.6 OEU12277.1 - 3.4e-47 160.1 0.1 4.9e-47 159.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) AAA_11 PF13086.6 OEU12278.1 - 9.3e-15 55.1 0.1 9.8e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU12278.1 - 8.8e-07 29.4 0.0 1.1e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU12278.1 - 1.1e-06 28.5 0.1 1.2e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OEU12278.1 - 0.00056 19.3 0.0 0.00059 19.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OEU12278.1 - 0.00082 19.8 0.0 0.00083 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OEU12278.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 OEU12278.1 - 0.0014 18.2 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OEU12278.1 - 0.002 17.4 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 OEU12278.1 - 0.0025 18.3 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OEU12278.1 - 0.0031 17.0 0.0 0.0039 16.7 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 OEU12278.1 - 0.0099 15.0 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 OEU12278.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 OEU12278.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OEU12278.1 - 0.023 14.1 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 OEU12278.1 - 0.052 12.9 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 OEU12278.1 - 0.057 13.4 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OEU12278.1 - 0.062 13.5 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 OEU12278.1 - 0.067 13.0 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 OEU12278.1 - 0.079 12.7 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 OEU12278.1 - 0.088 12.6 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU12278.1 - 0.11 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OEU12278.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 OEU12278.1 - 0.19 11.7 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 OEU12278.1 - 0.25 11.3 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ham1p_like PF01725.16 OEU12279.1 - 3.4e-36 124.9 0.0 4.2e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Cyclin_N PF00134.23 OEU12280.1 - 1.7e-15 56.9 0.1 8.6e-15 54.6 0.1 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain VRP3 PF03536.15 OEU12280.1 - 0.062 12.8 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein Peptidase_M48 PF01435.18 OEU12281.1 - 8.4e-23 81.2 0.0 2.5e-22 79.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 Tim17 PF02466.19 OEU12282.1 - 3.5e-08 33.8 5.9 5.3e-08 33.2 5.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 OEU12282.1 - 0.17 12.1 4.0 1 9.5 0.4 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF883 PF05957.13 OEU12282.1 - 0.38 11.4 1.5 1.1 9.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2018 PF09442.10 OEU12283.1 - 3.4 8.7 9.2 70 4.5 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) Mob1_phocein PF03637.17 OEU12285.1 - 1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family PA28_beta PF02252.18 OEU12286.1 - 3e-18 65.9 0.0 5.9e-12 45.5 0.0 2.4 3 0 0 3 3 3 2 Proteasome activator pa28 beta subunit zf-CHCC PF10276.9 OEU12287.1 - 3.8e-14 52.5 0.7 5.3e-14 52.0 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 OEU12287.1 - 0.064 13.0 3.5 0.15 11.8 3.5 1.5 1 0 0 1 1 1 0 Zinc Finger domain AAA_28 PF13521.6 OEU12288.1 - 4.2e-24 85.6 0.0 7.1e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OEU12288.1 - 0.00066 19.6 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OEU12288.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 OEU12288.1 - 0.048 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PMT2_N PF17987.1 OEU12288.1 - 0.061 13.5 0.1 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Phosphoethanolamine N-methyltransferase 2 N-terminal MeaB PF03308.16 OEU12288.1 - 0.072 12.1 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ank_2 PF12796.7 OEU12289.1 - 1.2e-10 41.9 0.0 1.5e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU12289.1 - 4.4e-10 39.9 0.0 1.4e-07 31.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU12289.1 - 8.2e-10 38.7 0.0 9.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU12289.1 - 2.3e-08 34.1 0.1 0.0005 20.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OEU12289.1 - 4.7e-08 32.7 0.0 0.00073 19.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OEU12290.1 - 5.7e-17 62.1 2.3 1.7e-16 60.5 1.4 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU12290.1 - 8.6e-14 51.7 3.9 9.7e-08 32.4 0.7 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU12290.1 - 2e-11 43.0 0.9 0.021 15.3 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OEU12290.1 - 1.3e-08 34.9 4.9 1.7e-05 25.0 0.6 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU12290.1 - 6.5e-08 32.7 5.8 0.046 14.2 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OEU12291.1 - 1.2e-17 64.2 0.3 2.2e-13 50.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU12291.1 - 4.6e-16 58.7 0.5 2.1e-05 24.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU12291.1 - 5e-14 52.0 3.0 2.5e-05 24.5 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OEU12291.1 - 4.5e-13 48.1 0.1 0.0023 18.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OEU12291.1 - 2.5e-11 43.9 0.1 5.7e-07 30.0 0.0 2.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU12292.1 - 0.0077 16.6 0.0 0.038 14.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 OEU12292.1 - 0.0082 16.7 0.2 0.019 15.5 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF21 PF01595.20 OEU12296.1 - 5.5e-26 91.3 2.8 8.4e-26 90.7 2.8 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OEU12296.1 - 7.7e-15 55.1 2.2 2.6e-06 27.8 0.5 2.7 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 OEU12296.1 - 2.9e-08 33.6 0.0 1e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 Transporter associated domain AKNA PF12443.8 OEU12298.1 - 0.022 15.4 0.1 0.041 14.5 0.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor STPPase_N PF16891.5 OEU12298.1 - 0.17 12.4 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Acetyltransf_1 PF00583.25 OEU12299.1 - 8.4e-14 51.8 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU12299.1 - 2.8e-11 43.4 0.0 3.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU12299.1 - 1.3e-08 35.2 0.0 2e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU12299.1 - 6.4e-07 29.2 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OEU12299.1 - 0.0017 18.4 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OEU12299.1 - 0.021 14.3 0.5 0.033 13.7 0.1 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase JAB PF01398.21 OEU12299.1 - 0.058 13.4 0.0 0.3 11.1 0.0 1.9 1 1 1 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Acetyltransf_13 PF13880.6 OEU12299.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Peptidase_M14 PF00246.24 OEU12300.1 - 8.6e-18 65.1 0.0 1.2e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Na_H_antiporter PF03553.14 OEU12302.1 - 8.9e-26 90.8 16.5 3.5e-21 75.7 12.3 4.0 2 1 1 3 3 3 2 Na+/H+ antiporter family CitMHS PF03600.16 OEU12302.1 - 5.8e-06 25.7 0.7 5.8e-06 25.7 0.7 2.6 2 1 0 2 2 2 1 Citrate transporter NICE-3 PF07406.11 OEU12302.1 - 0.045 13.8 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 NICE-3 protein Proteasome PF00227.26 OEU12303.1 - 6.2e-37 126.9 0.0 8e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-MYND PF01753.18 OEU12304.1 - 1.6e-09 37.7 10.7 2.8e-09 36.9 10.7 1.4 1 0 0 1 1 1 1 MYND finger DZR PF12773.7 OEU12304.1 - 0.35 10.9 6.3 1.2 9.2 6.2 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OEU12304.1 - 0.38 10.2 6.7 3.3 7.3 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Peptidase_S28 PF05577.12 OEU12305.1 - 1.5e-52 178.9 0.1 2.2e-52 178.3 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 AMPKBI PF04739.15 OEU12305.1 - 2.2 8.6 3.8 1.4 9.3 1.7 1.7 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain CRA PF06589.11 OEU12305.1 - 5.1 7.2 7.6 10 6.3 7.6 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) MFS_1_like PF12832.7 OEU12306.1 - 3.5e-55 187.4 23.4 5e-52 177.0 23.4 2.4 1 1 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 OEU12306.1 - 2.4e-13 49.9 19.0 1.6e-07 30.7 7.3 2.0 1 1 1 2 2 2 2 Nucleoside H+ symporter MFS_1 PF07690.16 OEU12306.1 - 2.8e-10 39.7 40.7 1.5e-06 27.4 11.8 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 OEU12306.1 - 3.4e-06 26.1 7.6 3.4e-06 26.1 7.6 2.6 1 1 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 OEU12306.1 - 0.005 15.3 1.8 0.005 15.3 1.8 2.2 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 OEU12307.1 - 4.3e-38 131.2 7.5 5.2e-38 130.9 7.5 1.1 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 OEU12307.1 - 3.2e-10 39.6 5.8 3.2e-10 39.6 5.8 1.7 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_1 PF07690.16 OEU12307.1 - 1.2e-06 27.8 13.1 2.6e-06 26.6 10.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2542 PF10808.8 OEU12307.1 - 1.1 9.8 5.3 1.3 9.6 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2542) Mitofilin PF09731.9 OEU12308.1 - 0.084 11.7 34.4 0.1 11.4 34.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC27 PF09507.10 OEU12308.1 - 0.87 8.9 37.5 1.2 8.5 37.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF966 PF06136.13 OEU12308.1 - 2 8.1 22.7 3 7.5 22.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hamartin PF04388.12 OEU12308.1 - 3.9 6.0 19.5 4.9 5.7 19.5 1.1 1 0 0 1 1 1 0 Hamartin protein BAF1_ABF1 PF04684.13 OEU12308.1 - 5.3 6.0 23.2 7.5 5.5 23.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_M41 PF01434.18 OEU12309.1 - 1.9e-57 194.2 0.1 2.9e-57 193.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OEU12309.1 - 2.6e-42 144.4 0.0 4.9e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU12309.1 - 2.8e-12 46.2 0.0 9.3e-12 44.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OEU12309.1 - 1.6e-08 34.8 1.3 8.7e-08 32.5 0.9 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.6 OEU12309.1 - 6e-06 26.6 0.1 0.033 14.5 0.1 3.3 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 OEU12309.1 - 0.00025 20.4 0.1 0.00071 18.9 0.1 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 OEU12309.1 - 0.00035 20.6 0.3 0.043 13.8 0.2 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 OEU12309.1 - 0.00086 19.7 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU12309.1 - 0.0013 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU12309.1 - 0.0016 18.2 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1_Xtn PF16897.5 OEU12309.1 - 0.0096 15.9 0.1 0.29 11.2 0.2 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain IstB_IS21 PF01695.17 OEU12309.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OEU12309.1 - 0.014 15.8 0.5 0.36 11.2 0.2 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 OEU12309.1 - 0.025 15.1 0.1 0.13 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OEU12309.1 - 0.042 13.2 0.2 0.096 12.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 OEU12309.1 - 0.058 13.5 0.0 0.25 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2281 PF10047.9 OEU12309.1 - 0.1 13.3 0.1 12 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) AAA_7 PF12775.7 OEU12309.1 - 0.21 11.1 0.2 0.73 9.3 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF3684 PF12449.8 OEU12310.1 - 6e-109 365.4 0.0 1.7e-70 238.1 0.0 3.0 2 2 1 3 3 3 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 OEU12310.1 - 0.0019 18.1 0.2 0.0087 15.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DBD_Tnp_Hermes PF10683.9 OEU12310.1 - 0.024 14.3 0.0 0.078 12.7 0.0 1.9 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain WLM PF08325.10 OEU12310.1 - 0.035 14.2 0.4 0.09 12.8 0.4 1.6 1 0 0 1 1 1 0 WLM domain DUF3663 PF12404.8 OEU12310.1 - 0.079 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Peptidase Trypan_PARP PF05887.11 OEU12314.1 - 7.8 6.5 13.7 19 5.2 13.7 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATP-grasp_6 PF18419.1 OEU12316.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp-like domain RVT_2 PF07727.14 OEU12317.1 - 0.055 13.1 0.0 0.57 9.8 0.0 1.9 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 OEU12318.1 - 6e-70 231.3 0.7 1.8e-25 88.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OEU12318.1 - 0.2 10.8 1.1 6.5 5.8 0.2 3.1 3 1 0 3 3 3 0 Gammaproteobacterial serine protease CytB6-F_Fe-S PF08802.10 OEU12318.1 - 0.41 10.7 5.3 5.2 7.2 0.2 3.4 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit PfkB PF00294.24 OEU12319.1 - 1.4e-70 238.1 2.0 1.6e-70 237.8 2.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CLP_protease PF00574.23 OEU12320.1 - 1.1e-76 256.9 0.7 1.3e-76 256.6 0.7 1.0 1 0 0 1 1 1 1 Clp protease PAP_central PF04928.17 OEU12321.1 - 8.3e-63 211.7 0.1 1.3e-62 211.0 0.1 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OEU12321.1 - 1.8e-05 24.4 0.0 3.5e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OEU12321.1 - 3.6e-05 24.0 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OEU12321.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Fez1 PF06818.15 OEU12322.1 - 3.2 8.2 58.6 0.1 13.1 13.0 3.5 1 1 2 3 3 3 0 Fez1 DUF3584 PF12128.8 OEU12322.1 - 4.9 4.5 54.8 0.04 11.4 35.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CEP63 PF17045.5 OEU12322.1 - 7.5 6.4 59.5 0.23 11.4 27.4 3.7 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa FAM76 PF16046.5 OEU12322.1 - 9.2 5.5 41.6 0.55 9.5 20.4 2.4 2 0 0 2 2 2 0 FAM76 protein GDI PF00996.18 OEU12323.1 - 8e-39 133.4 0.2 3e-17 62.3 0.0 3.2 3 0 0 3 3 3 3 GDP dissociation inhibitor PTS_IIB PF02302.17 OEU12323.1 - 1.7 9.4 3.9 1.1 10.0 0.1 2.7 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit Methyltransf_12 PF08242.12 OEU12323.1 - 2 9.2 15.3 12 6.8 0.2 4.1 4 0 0 4 4 4 0 Methyltransferase domain DUF2457 PF10446.9 OEU12323.1 - 3.8 6.6 26.3 2.4 7.2 15.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Orbi_VP6 PF01516.16 OEU12324.1 - 0.18 11.3 3.2 0.39 10.2 3.2 1.5 1 0 0 1 1 1 0 Orbivirus helicase VP6 SET PF00856.28 OEU12325.1 - 2.3e-11 44.4 0.1 6.2e-11 43.0 0.1 1.7 1 1 0 1 1 1 1 SET domain Rep_fac-A_C PF08646.10 OEU12326.1 - 7.9e-33 113.3 7.8 8.2e-33 113.2 2.5 2.7 2 1 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OEU12326.1 - 8.7e-29 99.3 0.4 1.8e-25 88.7 0.1 3.0 2 1 1 3 3 3 2 Replication protein A OB domain Rep-A_N PF04057.12 OEU12326.1 - 3.1e-24 84.9 1.7 7.9e-24 83.6 1.7 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OEU12326.1 - 3.7e-10 39.7 4.3 1.2e-06 28.4 0.0 3.3 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain G3P_antiterm PF04309.12 OEU12326.1 - 0.016 14.6 0.7 0.028 13.8 0.7 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF2271 PF10029.9 OEU12326.1 - 0.063 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Pkinase PF00069.25 OEU12327.1 - 1.3e-25 90.3 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU12327.1 - 1.1e-15 57.6 0.0 1.5e-15 57.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4739 PF15893.5 OEU12327.1 - 0.011 15.3 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4739) APH PF01636.23 OEU12327.1 - 0.031 14.2 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family COPI_assoc PF08507.10 OEU12328.1 - 0.0013 18.8 12.9 0.0056 16.7 12.8 1.9 1 1 0 1 1 1 1 COPI associated protein DUF1206 PF06724.11 OEU12328.1 - 0.047 13.8 1.2 0.56 10.3 1.3 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) zf-C2H2_assoc PF16606.5 OEU12328.1 - 0.28 11.4 5.7 0.68 10.2 5.7 1.6 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF3985 PF13153.6 OEU12328.1 - 0.37 10.8 4.6 0.11 12.5 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3985) MAP70 PF07058.11 OEU12328.1 - 1.9 7.1 4.4 2.5 6.7 4.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Methyltransf_23 PF13489.6 OEU12330.1 - 4.5e-06 26.6 0.1 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU12330.1 - 0.0001 23.0 1.1 0.012 16.4 0.0 3.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU12330.1 - 0.0023 17.8 0.1 0.018 14.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU12330.1 - 0.0068 17.0 0.0 0.053 14.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain zf-C2H2_2 PF12756.7 OEU12331.1 - 2e-27 95.5 4.2 2e-27 95.5 4.2 2.4 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OEU12331.1 - 0.011 15.9 7.8 0.72 10.2 2.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OEU12331.1 - 0.012 16.3 3.3 0.13 13.2 1.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger PknG_rubred PF16919.5 OEU12331.1 - 0.12 12.5 0.3 0.29 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain zf-C2H2 PF00096.26 OEU12331.1 - 0.15 12.6 5.3 1.4 9.5 2.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Presenilin PF01080.17 OEU12331.1 - 1.8 7.2 3.7 2.8 6.6 3.7 1.2 1 0 0 1 1 1 0 Presenilin LSM PF01423.22 OEU12335.1 - 3.8e-17 61.7 0.1 5.1e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OEU12335.1 - 0.011 15.8 0.2 0.016 15.3 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 OEU12335.1 - 0.024 14.3 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Hfq protein BPL_C PF02237.17 OEU12335.1 - 0.031 14.2 1.0 0.054 13.4 1.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 OEU12335.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) 3HCDH_N PF02737.18 OEU12336.1 - 0.21 11.4 0.1 10 6.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RsfS PF02410.15 OEU12337.1 - 9.2e-20 70.9 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Coa1 PF08695.10 OEU12338.1 - 2.1e-05 24.2 0.1 5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF445 PF04286.12 OEU12338.1 - 0.049 13.4 0.3 0.076 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FAM176 PF14851.6 OEU12338.1 - 0.079 12.6 1.2 0.16 11.7 1.2 1.4 1 0 0 1 1 1 0 FAM176 family Glycos_transf_3 PF00591.21 OEU12339.1 - 5.4e-28 98.3 0.1 6.8e-13 48.8 0.1 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 OEU12339.1 - 3.5e-16 58.6 1.9 6.5e-16 57.7 1.9 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 OEU12339.1 - 2.7e-13 49.5 0.1 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain TylF PF05711.11 OEU12340.1 - 1e-06 28.3 0.0 8e-05 22.0 0.0 2.9 3 0 0 3 3 3 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 OEU12340.1 - 2.5e-05 25.2 0.2 0.00025 22.0 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain NMD3 PF04981.13 OEU12341.1 - 3.2e-52 177.4 4.1 4.1e-52 177.1 4.1 1.1 1 0 0 1 1 1 1 NMD3 family DNA_pack_C PF02499.15 OEU12341.1 - 0.046 12.7 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus RNHCP PF12647.7 OEU12341.1 - 1.9 8.5 9.9 32 4.6 6.9 3.3 2 1 0 2 2 2 0 RNHCP domain PNP_UDP_1 PF01048.20 OEU12342.1 - 3.7e-18 65.6 0.7 6e-18 65.0 0.7 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily DUF2163 PF09931.9 OEU12342.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) AA_kinase PF00696.28 OEU12343.1 - 2e-36 125.8 0.5 4.5e-34 118.1 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family Homoserine_dh PF00742.19 OEU12343.1 - 6.1e-28 97.9 0.0 1.5e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT PF01842.25 OEU12343.1 - 1e-14 54.0 1.4 4.4e-07 29.6 0.1 3.0 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OEU12343.1 - 2.9e-13 49.4 0.3 8e-06 25.6 0.0 2.8 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.16 OEU12343.1 - 8e-05 23.3 0.1 0.00039 21.1 0.0 2.2 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Peptidase_C48 PF02902.19 OEU12344.1 - 5e-24 85.3 6.8 2.3e-14 53.7 0.1 4.2 3 1 0 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 OEU12344.1 - 0.00015 22.1 0.5 0.0006 20.2 0.5 2.1 1 0 0 1 1 1 1 MULE transposase domain Peptidase_C5 PF00770.18 OEU12344.1 - 0.042 13.5 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 Adenovirus endoprotease Jiraiya PF15038.6 OEU12344.1 - 0.3 10.5 2.6 0.19 11.1 0.1 1.8 2 0 0 2 2 2 0 Jiraiya Pannexin_like PF12534.8 OEU12348.1 - 0.24 10.5 0.8 0.38 9.8 0.8 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Zip PF02535.22 OEU12348.1 - 0.31 10.2 3.9 0.41 9.8 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.13 OEU12348.1 - 0.82 8.0 7.0 1.1 7.5 7.0 1.3 1 0 0 1 1 1 0 Menin SURF6 PF04935.12 OEU12348.1 - 1 9.1 9.5 1.9 8.2 9.5 1.5 1 1 0 1 1 1 0 Surfeit locus protein 6 DUF4551 PF15087.6 OEU12348.1 - 7.7 5.2 11.4 12 4.5 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pyrophosphatase PF00719.19 OEU12349.1 - 3.1e-46 157.1 0.1 4.2e-46 156.7 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec66 PF09802.9 OEU12350.1 - 2.4e-14 53.3 1.0 3.5e-14 52.8 0.6 1.5 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 SKG6 PF08693.10 OEU12350.1 - 0.031 13.7 0.9 0.05 13.0 0.9 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Golgin_A5 PF09787.9 OEU12350.1 - 0.24 10.8 10.8 0.32 10.4 10.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMIE PF16038.5 OEU12350.1 - 0.79 9.6 3.4 1.7 8.6 3.4 1.5 1 0 0 1 1 1 0 TMIE protein IZUMO PF15005.6 OEU12350.1 - 1.4 9.4 5.1 1.9 9.0 4.8 1.4 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated PTS_IIA PF02255.16 OEU12350.1 - 2.3 8.3 10.2 4 7.6 7.4 2.5 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit 60KD_IMP PF02096.20 OEU12351.1 - 2.4e-51 173.9 0.4 3.2e-51 173.5 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein PGM_PMM_II PF02879.16 OEU12352.1 - 0.062 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MiAMP1 PF09117.10 OEU12352.1 - 0.1 12.9 2.8 9.9 6.5 0.2 3.5 3 0 0 3 3 3 0 MiAMP1 Sigma70_r2 PF04542.14 OEU12354.1 - 4.9e-15 55.0 0.0 8.3e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 OEU12354.1 - 2.2e-05 24.4 0.0 0.0064 16.6 0.1 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 OEU12354.1 - 0.0052 16.3 0.2 0.056 13.0 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 MerR PF00376.23 OEU12354.1 - 0.02 14.7 0.0 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 MerR family regulatory protein HTH_24 PF13412.6 OEU12354.1 - 0.02 14.4 0.1 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HU-CCDC81_euk_2 PF18289.1 OEU12354.1 - 0.025 14.7 0.0 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 Corazonin PF17308.2 OEU12354.1 - 0.034 14.5 0.5 0.3 11.5 0.0 2.3 2 1 0 2 2 2 0 Pro-corazonin HTH_AsnC-type PF13404.6 OEU12354.1 - 0.047 13.5 0.1 16 5.5 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RNA_pol PF00940.19 OEU12355.1 - 6.1e-151 503.0 0.0 1.8e-150 501.4 0.0 1.7 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OEU12355.1 - 5.6e-19 68.7 0.2 9.2e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Vinculin PF01044.19 OEU12355.1 - 0.0042 15.4 0.0 0.005 15.1 0.0 1.1 1 0 0 1 1 1 1 Vinculin family PepSY_2 PF13670.6 OEU12355.1 - 0.16 12.0 0.2 0.34 10.9 0.2 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain RNase_J_C PF17770.1 OEU12355.1 - 1.2 10.3 2.8 17 6.5 0.1 3.2 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain Dynein_light PF01221.18 OEU12356.1 - 2.3e-41 140.0 1.4 2.6e-41 139.8 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Cytidylate_kin PF02224.18 OEU12356.1 - 0.032 14.0 0.1 0.036 13.8 0.1 1.0 1 0 0 1 1 1 0 Cytidylate kinase Imm48 PF15574.6 OEU12356.1 - 0.053 13.3 0.2 0.069 12.9 0.2 1.2 1 0 0 1 1 1 0 Immunity protein 48 MMR_HSR1 PF01926.23 OEU12357.1 - 4e-09 36.5 0.6 9.9e-09 35.3 0.6 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU12357.1 - 2.1e-05 24.5 0.2 3.6e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OEU12357.1 - 0.00052 20.1 0.2 0.003 17.6 0.0 2.0 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 OEU12357.1 - 0.038 14.2 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 OEU12357.1 - 0.061 13.2 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Spore_IV_A PF09547.10 OEU12357.1 - 0.064 12.2 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_29 PF13555.6 OEU12357.1 - 0.065 13.0 0.2 0.52 10.1 0.0 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 OEU12357.1 - 0.084 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 OEU12357.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 OEU12357.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 OEU12357.1 - 0.16 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PsbM PF05151.12 OEU12358.1 - 0.038 13.8 1.3 0.038 13.8 1.3 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) Chloroa_b-bind PF00504.21 OEU12359.1 - 2.6e-31 109.3 0.1 3.9e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF5547 PF17701.1 OEU12359.1 - 0.15 11.9 0.3 0.28 11.0 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5547) FtsJ PF01728.19 OEU12360.1 - 2.4e-14 53.9 0.2 4.5e-14 52.9 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Pentapeptide PF00805.22 OEU12361.1 - 6.6e-22 76.8 8.9 7.9e-09 35.0 1.0 4.2 2 1 1 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OEU12361.1 - 3e-14 52.9 1.9 2.1e-07 31.0 0.2 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 OEU12361.1 - 2.6e-12 46.7 11.1 1.7e-06 28.1 1.3 3.4 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) CWC25 PF12542.8 OEU12362.1 - 3.9e-12 47.0 3.6 3.9e-12 47.0 3.6 5.5 4 2 1 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.9 OEU12362.1 - 4.3e-11 42.8 13.5 4.3e-11 42.8 13.5 4.1 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR VCBS PF13517.6 OEU12363.1 - 0.00019 21.9 0.5 5.4 7.7 0.0 3.9 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OEU12363.1 - 0.73 10.0 9.3 0.78 9.9 0.6 3.3 3 0 0 3 3 3 0 FG-GAP repeat TGT PF01702.18 OEU12364.1 - 5.8e-17 61.9 0.1 8e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RPE65 PF03055.15 OEU12365.1 - 4.6e-78 263.5 0.0 5.5e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Yos1 PF08571.10 OEU12366.1 - 2.7e-14 53.2 0.1 3e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Yos1-like Aldo_ket_red PF00248.21 OEU12367.1 - 5.1e-26 91.5 0.3 1.1e-23 83.9 0.3 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3631 PF12307.8 OEU12367.1 - 0.03 14.5 0.2 0.088 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Ribosomal_L32e PF01655.18 OEU12367.1 - 0.13 12.7 0.0 0.53 10.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L32 UreE_N PF02814.15 OEU12367.1 - 0.2 11.3 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Acetyltransf_1 PF00583.25 OEU12368.1 - 2.4e-13 50.4 0.0 4.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU12368.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU12368.1 - 6.2e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU12368.1 - 0.00029 20.7 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OEU12368.1 - 0.0004 20.6 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU12368.1 - 0.001 19.1 0.7 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU12368.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase VCH_CASS14 PF18315.1 OEU12368.1 - 0.048 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Acetyltransf_13 PF13880.6 OEU12368.1 - 0.18 11.8 0.1 0.58 10.2 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase RNA_pol_Rpc4 PF05132.14 OEU12369.1 - 1.5e-22 80.6 0.0 1.5e-22 80.6 0.0 3.2 4 0 0 4 4 4 1 RNA polymerase III RPC4 Tir_receptor_M PF03549.14 OEU12369.1 - 0.087 13.2 0.3 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain GldM_N PF12081.8 OEU12369.1 - 0.28 11.3 1.7 0.45 10.6 1.7 1.3 1 0 0 1 1 1 0 GldM N-terminal domain AA_kinase PF00696.28 OEU12370.1 - 4.4e-30 105.1 0.5 7.8e-30 104.2 0.5 1.4 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 OEU12370.1 - 4.6e-11 41.9 0.1 3.6e-09 35.7 0.1 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family bZIP_1 PF00170.21 OEU12371.1 - 1.5e-08 34.6 6.7 1.5e-08 34.6 6.7 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OEU12371.1 - 5.3e-05 23.2 13.6 5.3e-05 23.2 13.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU12371.1 - 0.0084 16.6 3.6 0.0084 16.6 3.6 2.3 3 0 0 3 3 3 1 bZIP Maf transcription factor Tctex-1 PF03645.13 OEU12371.1 - 0.12 12.6 2.2 13 6.1 0.0 2.8 3 0 0 3 3 3 0 Tctex-1 family ApoL PF05461.11 OEU12371.1 - 0.41 9.9 5.7 0.28 10.5 2.9 1.9 1 1 1 2 2 2 0 Apolipoprotein L XhlA PF10779.9 OEU12371.1 - 0.84 9.9 4.9 0.42 10.8 1.3 2.1 2 0 0 2 2 2 0 Haemolysin XhlA FSA_C PF10479.9 OEU12372.1 - 0.034 12.3 0.6 0.038 12.1 0.6 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3391 PF11871.8 OEU12372.1 - 0.21 12.1 2.8 0.36 11.4 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1415 PF07209.12 OEU12374.1 - 0.0006 19.6 0.6 0.023 14.5 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1415) AnfO_nitrog PF09582.10 OEU12376.1 - 0.05 12.9 1.4 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) SUIM_assoc PF16619.5 OEU12376.1 - 8.5 6.5 23.5 3 8.0 1.7 4.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Bac_export_1 PF01311.20 OEU12377.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial export proteins, family 1 SET PF00856.28 OEU12379.1 - 0.037 14.4 0.1 0.47 10.8 0.0 2.1 2 1 0 2 2 2 0 SET domain DUF3016 PF11454.8 OEU12379.1 - 0.37 10.5 2.9 0.44 10.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3016) Radical_SAM PF04055.21 OEU12380.1 - 9.2e-17 61.9 0.0 2.3e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 OEU12380.1 - 6e-08 33.1 0.2 1.6e-07 31.7 0.2 1.8 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family DnaJ_C PF01556.18 OEU12381.1 - 3.6e-32 111.5 0.0 5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OEU12381.1 - 1.1e-23 83.1 3.5 2.2e-23 82.1 3.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OEU12381.1 - 0.0083 16.5 7.0 0.017 15.4 7.0 1.5 1 0 0 1 1 1 1 DnaJ central domain GerD PF17898.1 OEU12382.1 - 3.2e-06 27.1 31.5 0.0087 16.0 13.6 3.2 1 1 2 3 3 3 2 Spore germination GerD central core domain Ins_allergen_rp PF06757.13 OEU12382.1 - 0.00028 20.9 0.4 0.69 9.9 0.0 2.2 2 0 0 2 2 2 2 Insect allergen related repeat, nitrile-specifier detoxification Nif11 PF07862.11 OEU12382.1 - 0.00091 19.5 2.3 2.6 8.4 0.1 3.9 2 2 2 4 4 4 2 Nif11 domain STI1 PF17830.1 OEU12382.1 - 0.0021 18.0 37.2 0.069 13.1 15.6 5.2 2 2 2 4 4 4 2 STI1 domain DUF615 PF04751.14 OEU12382.1 - 0.021 14.8 4.8 1.2 9.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF615) SapB_1 PF05184.15 OEU12382.1 - 0.14 12.2 3.3 1.6 8.8 0.2 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 L27 PF02828.16 OEU12382.1 - 0.16 11.8 0.3 23 4.9 0.1 2.4 2 0 0 2 2 2 0 L27 domain T3SS_needle_F PF09392.10 OEU12382.1 - 0.32 11.2 19.1 7.1 6.9 3.1 4.7 1 1 3 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Not1 PF04054.15 OEU12382.1 - 0.57 9.0 7.3 2 7.2 1.2 2.0 1 1 1 2 2 2 0 CCR4-Not complex component, Not1 Com_YlbF PF06133.11 OEU12382.1 - 1.8 9.2 18.1 1.3 9.7 1.3 3.2 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA zf-C2H2_jaz PF12171.8 OEU12383.1 - 2.8e-09 37.0 11.3 5.1e-07 29.8 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OEU12383.1 - 2.4e-07 30.9 0.3 2.4e-07 30.9 0.3 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OEU12383.1 - 0.00021 21.5 7.4 0.0031 17.8 1.4 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OEU12383.1 - 0.00042 20.9 8.0 0.15 13.0 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4187 PF13821.6 OEU12383.1 - 0.0094 15.7 5.8 0.096 12.5 0.8 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4187) zf-DBF PF07535.12 OEU12383.1 - 0.021 14.9 7.8 0.31 11.2 0.2 2.6 2 0 0 2 2 2 0 DBF zinc finger zf-BED PF02892.15 OEU12383.1 - 0.029 14.4 4.4 2 8.5 0.3 2.6 1 1 1 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 OEU12383.1 - 0.098 13.0 3.6 0.27 11.6 3.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OEU12383.1 - 0.18 12.3 11.5 0.38 11.3 1.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type AKAP95 PF04988.12 OEU12383.1 - 9.4 6.4 14.4 0.23 11.7 0.5 2.9 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Sua5_yciO_yrdC PF01300.18 OEU12384.1 - 0.11 11.9 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Telomere recombination FHA PF00498.26 OEU12385.1 - 1.1e-14 54.5 0.2 3.4e-14 52.9 0.2 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OEU12385.1 - 1.1e-05 25.7 0.0 3.7e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CTP_transf_like PF01467.26 OEU12385.1 - 0.031 14.5 0.1 0.083 13.1 0.1 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like EDS1_EP PF18117.1 OEU12385.1 - 0.041 14.3 0.7 0.16 12.4 0.7 2.1 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain Cpn60_TCP1 PF00118.24 OEU12386.1 - 1.7e-82 277.6 9.0 2.6e-82 277.0 9.0 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1681 PF07933.14 OEU12387.1 - 5.9e-47 159.1 0.0 7.5e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF1623 PF07785.11 OEU12387.1 - 0.22 11.7 0.3 3.6 7.8 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1623) APS_kinase PF01583.20 OEU12388.1 - 1.1e-65 220.4 0.1 4.7e-63 211.8 0.1 2.1 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OEU12388.1 - 0.00048 20.3 0.0 0.0017 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OEU12388.1 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OEU12388.1 - 0.0025 18.4 0.4 0.0055 17.3 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU12388.1 - 0.0067 16.8 0.0 0.0084 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain PRK PF00485.18 OEU12388.1 - 0.01 15.6 0.1 0.019 14.7 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 OEU12388.1 - 0.014 15.9 0.6 0.023 15.2 0.5 1.6 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 OEU12388.1 - 0.06 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 OEU12388.1 - 0.062 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OEU12388.1 - 0.087 13.1 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OEU12388.1 - 0.098 12.2 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Ribosom_S12_S23 PF00164.25 OEU12391.1 - 2.3e-48 162.6 0.6 2.7e-48 162.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF3727 PF12527.8 OEU12392.1 - 4.5e-21 74.9 4.9 4.5e-21 74.9 4.9 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3727) Sigma70_ner PF04546.13 OEU12392.1 - 0.0099 15.8 2.1 0.014 15.2 2.1 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region RXT2_N PF08595.11 OEU12392.1 - 0.056 13.5 0.9 0.092 12.8 0.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 OEU12392.1 - 0.75 7.8 6.5 0.93 7.5 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi ProRS-C_2 PF09181.10 OEU12392.1 - 1.2 9.3 4.2 0.4 10.8 0.4 2.1 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal DUF2457 PF10446.9 OEU12392.1 - 2.5 7.1 12.7 3.4 6.7 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Importin_rep_4 PF18808.1 OEU12392.1 - 5.3 7.4 8.5 14 6.0 8.5 1.8 1 1 0 1 1 1 0 Importin repeat E7 PF00527.18 OEU12392.1 - 8.7 6.6 9.1 6.3 7.1 5.5 2.3 2 0 0 2 2 2 0 E7 protein, Early protein Methyltransf_22 PF13383.6 OEU12393.1 - 0.051 13.1 0.2 0.065 12.8 0.2 1.1 1 0 0 1 1 1 0 Methyltransferase domain Pyrid_oxidase_2 PF13883.6 OEU12394.1 - 1.5e-31 109.6 0.0 1.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AAA_16 PF13191.6 OEU12395.1 - 5.2e-07 30.2 1.4 0.012 16.0 0.1 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.29 OEU12395.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OEU12395.1 - 4.2e-05 23.8 0.1 0.00011 22.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain ORC4_C PF14629.6 OEU12395.1 - 0.00029 20.3 0.0 0.00029 20.3 0.0 1.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_29 PF13555.6 OEU12395.1 - 0.00079 19.1 0.2 0.0018 18.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.9 OEU12395.1 - 0.01 15.0 0.1 0.032 13.4 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 OEU12395.1 - 0.012 15.6 0.5 1 9.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain DUF4194 PF13835.6 OEU12395.1 - 0.012 15.3 0.1 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) AAA_5 PF07728.14 OEU12395.1 - 0.016 15.2 0.1 0.17 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OEU12395.1 - 0.022 14.4 0.2 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OEU12395.1 - 0.034 13.9 0.1 0.082 12.6 0.1 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OEU12395.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD_2 PF06733.15 OEU12396.1 - 1.4e-49 168.1 0.9 2.5e-49 167.3 0.9 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 OEU12396.1 - 1.6e-45 155.4 0.3 2.9e-44 151.2 0.0 2.7 3 0 0 3 3 3 1 Helicase C-terminal domain HBB PF06777.11 OEU12396.1 - 9.2e-24 84.2 0.0 2.8e-18 66.3 0.0 3.4 3 1 0 3 3 3 2 Helical and beta-bridge domain ResIII PF04851.15 OEU12396.1 - 3.2e-08 33.7 0.0 0.0005 20.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU12396.1 - 0.00015 21.6 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF2075 PF09848.9 OEU12396.1 - 0.023 14.0 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OEU12396.1 - 0.11 12.8 0.5 13 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain YL1_C PF08265.11 OEU12398.1 - 3.4e-06 26.7 0.0 6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain HEPN_Toprim_N PF18871.1 OEU12398.1 - 0.048 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 WSK PF03832.13 OEU12398.1 - 1.2 8.8 6.5 2.7 7.8 6.5 1.6 1 0 0 1 1 1 0 WSK motif TrkA_TMD PF18613.1 OEU12399.1 - 0.38 10.2 3.5 1.5 8.3 3.5 2.1 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain FAM165 PF14981.6 OEU12399.1 - 2.8 7.8 0.0 2.8 7.8 0.0 3.2 3 1 0 3 3 3 0 FAM165 family EamA PF00892.20 OEU12400.1 - 8.1e-15 55.2 35.3 5.2e-09 36.4 15.9 3.6 2 2 1 3 3 3 2 EamA-like transporter family p450 PF00067.22 OEU12401.1 - 6.2e-46 157.1 0.0 7.4e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0489 PF12640.7 OEU12402.1 - 3.8e-36 125.0 5.9 6.1e-34 117.8 5.9 2.3 1 1 0 1 1 1 1 UPF0489 domain NUDIX PF00293.28 OEU12404.1 - 3.8e-06 27.0 0.0 8.9e-06 25.8 0.0 1.6 1 1 1 2 2 2 1 NUDIX domain Rep_1B PF17873.1 OEU12404.1 - 0.052 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Replicase polyprotein 1ab RusA PF05866.11 OEU12405.1 - 3.4e-13 50.2 0.4 6.9e-13 49.2 0.4 1.5 1 1 0 1 1 1 1 Endodeoxyribonuclease RusA SAP PF02037.27 OEU12406.1 - 4.7e-07 29.4 1.0 4.7e-07 29.4 1.0 1.7 2 0 0 2 2 2 1 SAP domain PRiA4_ORF3 PF07929.11 OEU12406.1 - 0.00044 20.0 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Zeta_toxin PF06414.12 OEU12410.1 - 1.8e-34 118.8 0.0 3.1e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 OEU12410.1 - 2.4e-11 44.0 0.0 9e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OEU12410.1 - 4e-05 24.2 0.0 0.45 11.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain Microtub_bd PF16796.5 OEU12410.1 - 0.00086 19.3 0.1 0.83 9.6 0.2 2.8 2 1 0 2 2 2 2 Microtubule binding AAA_17 PF13207.6 OEU12410.1 - 0.013 15.9 0.0 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.23 OEU12410.1 - 0.027 13.4 0.1 1.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Kinesin motor domain DUF4298 PF14131.6 OEU12411.1 - 0.012 15.5 0.4 0.12 12.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Imm3 PF14425.6 OEU12411.1 - 0.049 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm3 HRDC PF00570.23 OEU12411.1 - 0.11 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 HRDC domain CactinC_cactus PF09732.9 OEU12412.1 - 1.2e-56 190.0 6.1 1.4e-56 189.8 6.1 1.0 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein HhH-GPD PF00730.25 OEU12413.1 - 2.6e-14 53.6 0.0 4.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Dimer_Tnp_hAT PF05699.14 OEU12413.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2083 PF09856.9 OEU12413.1 - 0.13 12.1 0.7 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Predicted transcriptional regulator (DUF2083) RRM_1 PF00076.22 OEU12414.1 - 1.7e-24 85.4 0.1 2.7e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU12414.1 - 0.0023 17.5 0.1 0.0034 17.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 OEU12414.1 - 0.0039 17.0 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 OEU12414.1 - 0.0095 15.8 0.0 0.029 14.2 0.0 1.8 1 1 1 2 2 2 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 OEU12414.1 - 0.025 14.4 0.4 0.3 10.9 0.5 2.1 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 OEU12414.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif Glutaredoxin PF00462.24 OEU12415.1 - 5.6e-15 55.3 0.0 8.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OEU12415.1 - 0.0086 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OEU12415.1 - 0.063 13.7 0.2 0.11 12.9 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Sec34 PF04136.15 OEU12416.1 - 1.7e-05 24.8 7.1 5.6e-05 23.1 0.1 4.6 4 2 0 4 4 4 1 Sec34-like family Imm5 PF14423.6 OEU12416.1 - 0.012 15.8 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 0 Immunity protein Imm5 ParcG PF10274.9 OEU12416.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein Methyltransf_23 PF13489.6 OEU12417.1 - 3.2e-23 82.4 0.0 1.5e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU12417.1 - 1.1e-15 58.1 0.0 1.7e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU12417.1 - 1.9e-14 54.1 0.0 4.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU12417.1 - 6.6e-11 42.0 0.0 9.4e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU12417.1 - 1.1e-10 42.1 0.0 8.3e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU12417.1 - 3.2e-10 40.0 0.0 7.3e-10 38.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 OEU12417.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 OEU12417.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Macoilin PF09726.9 OEU12418.1 - 0.14 10.7 9.6 0.18 10.4 9.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF296 PF03479.15 OEU12419.1 - 2.6e-25 88.8 0.5 3.2e-25 88.6 0.5 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Ric8 PF10165.9 OEU12422.1 - 2.3e-11 43.4 0.0 4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn UvsW PF11637.8 OEU12422.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW Exo_endo_phos PF03372.23 OEU12423.1 - 4.3e-09 36.2 0.0 1.6e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OEU12423.1 - 0.0077 16.1 0.0 0.21 11.5 0.0 2.9 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Myco_arth_vir_N PF09610.10 OEU12424.1 - 0.061 13.4 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) adh_short PF00106.25 OEU12426.1 - 9e-24 84.0 0.6 3.2e-21 75.7 0.2 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU12426.1 - 2e-12 47.2 0.1 4.6e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OEU12426.1 - 2.6e-08 33.7 0.0 3.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OEU12426.1 - 3.3e-07 30.4 0.1 5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OEU12426.1 - 5e-05 23.3 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Pyr_redox_3 PF13738.6 OEU12426.1 - 0.00075 18.8 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ATP-synt_F PF01990.17 OEU12426.1 - 0.0037 17.6 0.6 0.013 15.8 0.1 2.0 2 0 0 2 2 2 1 ATP synthase (F/14-kDa) subunit GDP_Man_Dehyd PF16363.5 OEU12426.1 - 0.0042 16.5 0.3 0.026 13.9 0.2 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase QRPTase_C PF01729.19 OEU12426.1 - 0.013 15.2 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 OEU12426.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 OEU12426.1 - 0.015 14.7 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_2 PF03446.15 OEU12426.1 - 0.025 14.7 0.3 0.046 13.9 0.3 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 OEU12426.1 - 0.056 13.4 0.3 0.26 11.3 0.3 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_tran_WecB PF03808.13 OEU12426.1 - 0.058 13.3 0.1 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GARS_C PF02843.16 OEU12426.1 - 0.11 12.8 0.2 0.31 11.3 0.2 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain 3HCDH_N PF02737.18 OEU12426.1 - 0.12 12.2 1.2 0.17 11.7 0.3 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BLM_N PF16202.5 OEU12427.1 - 0.022 13.9 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein UL42 PF17638.2 OEU12428.1 - 0.8 9.7 7.9 2.3 8.2 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 DapB_C PF05173.14 OEU12430.1 - 3.4e-18 65.8 0.2 6e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 OEU12430.1 - 2.2e-11 44.0 0.0 5.2e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus MMPL PF03176.15 OEU12430.1 - 0.061 12.2 0.3 0.14 11.0 0.1 1.7 2 0 0 2 2 2 0 MMPL family DUF179 PF02622.15 OEU12431.1 - 1.5e-35 122.5 0.2 2.8e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized ACR, COG1678 FKBP_C PF00254.28 OEU12431.1 - 0.05 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase ubiquitin PF00240.23 OEU12432.1 - 1.6e-57 191.1 3.9 7.9e-28 96.0 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OEU12432.1 - 2.6e-33 113.7 7.2 4.8e-16 58.3 0.8 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU12432.1 - 5.5e-08 33.2 1.6 0.0082 16.6 0.1 2.8 2 1 1 3 3 2 2 Ubiquitin-like domain RBD PF02196.15 OEU12432.1 - 4.1e-05 23.6 0.0 0.55 10.3 0.0 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain TBK1_ULD PF18396.1 OEU12432.1 - 0.00011 22.1 0.2 0.88 9.5 0.0 2.7 3 0 0 3 3 3 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OEU12432.1 - 0.00012 22.4 0.7 0.5 10.8 0.1 2.4 1 1 1 2 2 2 2 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU12432.1 - 0.00016 21.7 5.2 9.2 6.4 0.5 4.3 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU12432.1 - 0.00016 21.7 0.0 1.1 9.4 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like NETI PF14044.6 OEU12432.1 - 0.02 14.6 0.6 8.7 6.2 0.1 2.7 2 0 0 2 2 2 0 NETI protein Ldt_C PF17969.1 OEU12432.1 - 0.041 14.6 0.1 49 4.8 0.0 3.4 3 0 0 3 3 3 0 L,D-transpeptidase C-terminal domain Phage_sheath_1N PF17481.2 OEU12432.1 - 0.077 13.5 4.2 6.6 7.3 0.4 2.6 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain GYD PF08734.11 OEU12432.1 - 0.095 12.7 0.1 22 5.1 0.0 2.5 2 0 0 2 2 2 0 GYD domain Fer2 PF00111.27 OEU12432.1 - 0.15 12.0 0.9 23 5.0 0.1 2.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain GST_N_4 PF17172.4 OEU12433.1 - 7.6e-08 33.0 0.6 6.6e-07 30.0 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OEU12433.1 - 1.1e-06 28.3 0.2 2.5e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU12433.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PDH PF02153.17 OEU12435.1 - 1.5e-13 50.4 0.0 2.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 OEU12435.1 - 1.6e-05 25.4 0.0 3.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OEU12435.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OEU12435.1 - 0.00095 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 OEU12435.1 - 0.0014 18.0 0.0 0.0048 16.3 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OEU12435.1 - 0.0091 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OEU12435.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OEU12435.1 - 0.11 12.2 0.2 0.61 9.7 0.2 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HEM4 PF02602.15 OEU12436.1 - 7e-37 127.0 0.0 9.6e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PGM_PMM_I PF02878.16 OEU12437.1 - 5.3e-29 100.7 0.0 8.2e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OEU12437.1 - 9.9e-20 70.8 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OEU12437.1 - 6.3e-13 49.2 0.0 2.2e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OEU12437.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain PFK PF00365.20 OEU12438.1 - 8.1e-28 97.6 0.0 2.9e-27 95.7 0.0 1.8 1 1 0 1 1 1 1 Phosphofructokinase Med24_N PF11277.8 OEU12439.1 - 0.0047 15.0 0.1 0.0067 14.6 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal PBP1_TM PF14812.6 OEU12441.1 - 0.76 10.2 4.0 1.9 8.9 4.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OEU12441.1 - 0.8 9.4 5.7 1.4 8.6 5.7 1.4 1 0 0 1 1 1 0 FAM176 family TFIID-18kDa PF02269.16 OEU12443.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF5320 PF17253.2 OEU12443.1 - 0.71 11.0 37.6 1.4 10.1 19.4 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) AA_kinase PF00696.28 OEU12448.1 - 1.2e-45 156.1 0.1 2.7e-45 154.9 0.0 1.6 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 OEU12448.1 - 8.4e-06 25.5 0.9 0.079 12.8 0.0 2.8 1 1 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OEU12448.1 - 0.00036 20.3 2.3 0.0051 16.6 1.0 2.6 2 0 0 2 2 2 1 ACT domain Cu-oxidase_2 PF07731.14 OEU12449.1 - 3.2e-15 56.1 1.3 1.6e-14 53.8 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase PAPA-1 PF04795.12 OEU12449.1 - 0.15 12.8 3.5 0.27 12.0 3.5 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region Dirigent PF03018.14 OEU12450.1 - 0.0067 16.2 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 Dirigent-like protein Ribosomal_L22 PF00237.19 OEU12451.1 - 1.2e-29 102.5 0.1 1.7e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fasciclin PF02469.22 OEU12452.1 - 3.2e-34 117.9 0.1 3.6e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Fasciclin domain Mit_KHE1 PF10173.9 OEU12453.1 - 0.22 11.6 2.5 13 5.8 0.4 2.7 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related MRPL52 PF18699.1 OEU12453.1 - 3.6 7.9 8.5 0.37 11.0 3.3 1.9 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Polyketide_cyc2 PF10604.9 OEU12454.1 - 1.2e-17 64.5 0.0 1.5e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Mito_carr PF00153.27 OEU12455.1 - 1.2e-27 95.6 0.8 7.7e-17 61.0 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein ubiquitin PF00240.23 OEU12456.1 - 1.2e-34 117.8 0.4 1.3e-34 117.7 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU12456.1 - 5.7e-17 61.3 0.7 6.2e-17 61.2 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU12456.1 - 2.4e-06 27.9 0.1 9.9e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU12456.1 - 0.0009 19.1 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU12456.1 - 0.0023 18.0 0.1 0.005 16.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OEU12456.1 - 0.0036 17.6 0.0 0.0044 17.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU12456.1 - 0.0045 17.0 0.2 2.3 8.4 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 OEU12456.1 - 0.024 15.2 0.0 0.026 15.1 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HLH PF00010.26 OEU12457.1 - 2.2 8.3 4.3 22 5.1 0.0 2.7 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Sulfotransfer_1 PF00685.27 OEU12458.1 - 1.6e-14 54.0 0.0 3.2e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 OEU12458.1 - 0.0017 18.3 0.1 0.003 17.5 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 OEU12458.1 - 0.0026 18.2 0.2 0.048 14.0 0.1 2.8 1 1 1 2 2 2 1 Sulfotransferase family LOR PF04525.12 OEU12459.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 LURP-one-related AMP-binding PF00501.28 OEU12463.1 - 4.5e-35 121.1 0.4 4e-32 111.3 0.1 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Ank_2 PF12796.7 OEU12463.1 - 5.2e-15 55.8 0.7 5.8e-07 30.0 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU12463.1 - 7.2e-12 45.6 2.3 0.00053 20.5 0.1 4.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU12463.1 - 2.9e-11 42.5 1.6 0.023 15.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OEU12463.1 - 8.9e-08 32.3 4.7 0.0035 17.7 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OEU12463.1 - 1.7e-05 25.0 11.5 0.0014 18.9 0.0 5.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Lyase_8 PF02278.18 OEU12464.1 - 0.0072 15.8 0.8 0.0091 15.5 0.8 1.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain DUF4834 PF16118.5 OEU12464.1 - 3.7 8.6 9.0 0.39 11.7 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DpaA_N PF16924.5 OEU12465.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain DUF4251 PF14059.6 OEU12466.1 - 0.086 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) UPF0697 PF15117.6 OEU12467.1 - 0.0069 16.4 0.5 0.012 15.7 0.5 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0697 TPR_7 PF13176.6 OEU12467.1 - 0.038 14.0 0.0 0.86 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU12467.1 - 0.09 12.9 0.1 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU12467.1 - 0.12 12.2 1.0 4.6 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Shadoo PF14999.6 OEU12468.1 - 0.22 11.6 4.4 0.37 10.9 4.4 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Cation_efflux PF01545.21 OEU12469.1 - 5.8e-10 39.2 9.9 1.3e-09 38.0 9.9 1.6 1 1 0 1 1 1 1 Cation efflux family TMEM154 PF15102.6 OEU12469.1 - 0.89 9.5 12.5 3.9 7.4 1.4 3.7 3 0 0 3 3 3 0 TMEM154 protein family DUF5056 PF16479.5 OEU12469.1 - 0.9 9.8 4.1 47 4.3 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5056) Band_3_cyto PF07565.13 OEU12469.1 - 1.3 8.8 5.9 0.16 11.8 0.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Kelch_1 PF01344.25 OEU12470.1 - 0.0058 16.2 8.4 0.12 11.9 1.9 4.4 5 1 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 OEU12470.1 - 0.036 14.1 6.0 0.043 13.8 1.1 3.3 2 2 1 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.6 OEU12470.1 - 0.12 12.6 3.9 2.1 8.7 1.0 3.3 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.6 OEU12470.1 - 0.13 12.6 0.2 0.77 10.1 0.0 2.4 2 0 0 2 2 2 0 Kelch motif 7TM_GPCR_Srab PF10292.9 OEU12472.1 - 0.61 9.0 2.8 0.86 8.5 2.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor WASH-7_C PF14746.6 OEU12472.1 - 0.73 9.5 5.9 0.15 11.8 0.3 2.0 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal SPT16 PF08644.11 OEU12472.1 - 3.3 7.9 7.5 0.6 10.3 2.9 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4834 PF16118.5 OEU12472.1 - 9.1 7.3 16.1 3.9 8.5 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PT PF04886.12 OEU12474.1 - 2.4e-16 59.0 58.0 2.2e-06 27.1 21.6 3.1 1 1 1 2 2 2 2 PT repeat LRR_8 PF13855.6 OEU12475.1 - 4.3e-06 26.4 4.7 4.3e-06 26.4 4.7 2.0 1 1 1 2 2 2 2 Leucine rich repeat DUF3338 PF11819.8 OEU12475.1 - 0.00075 19.5 0.1 0.15 12.0 0.1 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF3338) LRR_4 PF12799.7 OEU12475.1 - 0.011 16.2 9.4 0.046 14.1 6.0 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU12475.1 - 0.062 13.9 6.1 1.8 9.4 0.2 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat BRK PF07533.16 OEU12476.1 - 0.16 11.6 0.2 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 BRK domain BaxI_1 PF12811.7 OEU12476.1 - 0.44 10.1 9.9 0.095 12.2 6.6 1.6 2 0 0 2 2 2 0 Bax inhibitor 1 like DUF4383 PF14325.6 OEU12476.1 - 4.6 7.5 10.5 26 5.1 10.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) LapA_dom PF06305.11 OEU12476.1 - 6.1 6.7 9.2 45 4.0 2.9 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PXA PF02194.15 OEU12477.1 - 0.019 14.9 0.1 0.06 13.3 0.0 1.8 1 1 1 2 2 2 0 PXA domain MFS_1 PF07690.16 OEU12478.1 - 3.2e-06 26.3 36.3 0.00048 19.2 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7B PF05392.11 OEU12478.1 - 0.025 14.3 1.8 0.14 11.9 1.8 2.3 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB ubiquitin PF00240.23 OEU12479.1 - 3.9e-07 29.7 0.2 6.5e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU12479.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OEU12479.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF4512 PF14975.6 OEU12479.1 - 5.7 7.8 5.2 23 5.8 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF948 PF06103.11 OEU12480.1 - 0.087 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PT PF04886.12 OEU12481.1 - 0.00014 21.3 26.7 2.3e+02 1.4 26.7 3.1 1 1 0 1 1 1 0 PT repeat Hint PF01079.20 OEU12482.1 - 0.00062 19.3 0.5 0.00067 19.2 0.5 1.1 1 0 0 1 1 1 1 Hint module MIR PF02815.19 OEU12482.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 MIR domain Mei5_like PF17021.5 OEU12484.1 - 0.0011 19.0 4.3 0.044 13.8 0.1 2.2 1 1 1 2 2 2 2 Putative double-strand recombination repair-like DUF1043 PF06295.12 OEU12484.1 - 0.018 15.0 1.9 0.024 14.7 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) FdhE PF04216.12 OEU12484.1 - 0.051 13.4 0.2 0.066 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF4419 PF14388.6 OEU12484.1 - 0.066 12.6 1.9 0.13 11.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) Cnl2_NKP2 PF09447.10 OEU12484.1 - 0.11 12.6 1.4 11 6.3 1.4 2.4 1 1 0 1 1 1 0 Cnl2/NKP2 family protein DUF4407 PF14362.6 OEU12484.1 - 0.13 11.6 0.4 0.16 11.3 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PI_PP_I PF18363.1 OEU12484.1 - 0.55 10.4 4.7 0.93 9.7 2.4 2.0 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain Fasciclin PF02469.22 OEU12485.1 - 1.6e-05 25.1 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain zf-RanBP PF00641.18 OEU12486.1 - 0.9 8.9 9.0 0.036 13.4 2.9 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Anoctamin PF04547.12 OEU12487.1 - 2.5e-09 36.5 11.7 2.5e-09 36.5 11.7 2.2 2 1 0 2 2 2 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 OEU12487.1 - 2.5e-05 23.7 11.4 2.5e-05 23.7 11.4 2.8 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OEU12487.1 - 0.0061 16.8 0.0 0.085 13.1 0.0 2.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF1295 PF06966.12 OEU12487.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Sigma_reg_N PF13800.6 OEU12487.1 - 0.037 14.3 4.1 0.94 9.8 0.5 3.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal FixQ PF05545.11 OEU12487.1 - 0.051 13.5 0.4 0.051 13.5 0.4 4.2 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ Baculo_ODV-E27 PF05314.11 OEU12487.1 - 0.09 11.9 0.8 0.17 11.1 0.2 1.7 2 0 0 2 2 2 0 Baculovirus occlusion-derived virus envelope protein EC27 OAD_gamma PF04277.13 OEU12487.1 - 0.1 13.2 0.8 2.1 9.0 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Spo7 PF03907.13 OEU12487.1 - 0.17 11.3 2.2 0.62 9.5 0.1 2.3 2 0 0 2 2 2 0 Spo7-like protein DUF4381 PF14316.6 OEU12487.1 - 0.18 12.1 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SAYSvFN PF10260.9 OEU12487.1 - 0.24 11.3 2.8 1.5 8.8 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF4059 PF13268.6 OEU12487.1 - 3 8.3 8.2 8.6 6.9 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4059) FAM222A PF15258.6 OEU12489.1 - 1.3 8.0 28.4 2.1 7.3 28.4 1.3 1 0 0 1 1 1 0 Protein family of FAM222A Allantoicase PF03561.15 OEU12489.1 - 3.6 7.6 7.4 9.6 6.2 7.4 1.8 1 0 0 1 1 1 0 Allantoicase repeat Form_Nir_trans PF01226.17 OEU12491.1 - 1e-59 201.8 24.4 1.1e-59 201.6 24.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter NMN_transporter PF04973.12 OEU12491.1 - 0.0012 18.8 2.6 0.0012 18.8 2.6 2.1 2 0 0 2 2 2 1 Nicotinamide mononucleotide transporter Peptidase_M11 PF05548.11 OEU12492.1 - 3.1e-11 43.0 0.1 6.1e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Gametolysin peptidase M11 Neur_chan_memb PF02932.16 OEU12493.1 - 0.029 14.4 0.3 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PPP4R2 PF09184.11 OEU12493.1 - 0.039 13.6 14.0 0.059 13.0 14.0 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OEU12493.1 - 0.14 10.3 12.6 0.2 9.8 12.6 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1754 PF08555.10 OEU12493.1 - 0.37 11.6 17.1 0.76 10.6 4.2 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Pox_Ag35 PF03286.14 OEU12493.1 - 1.2 8.9 19.1 5.6 6.7 0.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 OEU12493.1 - 5 6.3 21.1 0.7 9.1 12.1 2.2 2 0 0 2 2 2 0 NOA36 protein Cytochrom_B561 PF03188.16 OEU12495.1 - 3e-10 40.4 4.2 4.6e-10 39.8 4.2 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2781 PF10914.8 OEU12495.1 - 0.065 13.6 1.0 0.12 12.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) DUF929 PF06053.11 OEU12496.1 - 0.013 14.8 0.5 0.025 13.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF1459 PF07312.11 OEU12496.1 - 0.088 13.0 5.5 1.7 8.9 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) KdgT PF03812.13 OEU12496.1 - 0.41 9.9 2.9 0.66 9.3 2.9 1.3 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease Spt20 PF12090.8 OEU12500.1 - 0.00031 20.4 22.8 0.0035 17.0 5.1 2.3 2 0 0 2 2 2 2 Spt20 family DUF4834 PF16118.5 OEU12500.1 - 0.009 17.0 9.3 0.23 12.4 1.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) Na_trans_assoc PF06512.13 OEU12500.1 - 0.017 15.4 3.8 0.071 13.4 0.3 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated CDC24_OB1 PF17246.2 OEU12500.1 - 0.035 14.2 0.2 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 DUF2722 PF10846.8 OEU12500.1 - 0.074 12.0 27.0 0.025 13.6 3.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF702 PF05142.12 OEU12500.1 - 0.081 13.4 6.6 0.78 10.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ctr PF04145.15 OEU12500.1 - 0.088 13.4 0.6 7.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family eIF-3_zeta PF05091.12 OEU12500.1 - 0.11 11.5 4.7 1.3 7.9 1.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ATAD4 PF15321.6 OEU12500.1 - 0.13 13.6 5.6 0.59 11.5 0.9 2.6 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 CPSF100_C PF13299.6 OEU12500.1 - 0.18 12.0 3.3 6.8 6.8 0.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 OEU12500.1 - 0.93 9.4 6.9 4.2 7.3 0.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ANAPC_CDC26 PF10471.9 OEU12500.1 - 1.3 9.9 29.0 7.1 7.6 10.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FAM176 PF14851.6 OEU12500.1 - 1.6 8.4 7.1 0.98 9.1 1.6 2.6 2 0 0 2 2 2 0 FAM176 family Pex14_N PF04695.13 OEU12500.1 - 3.5 8.3 13.9 3.4 8.3 2.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Androgen_recep PF02166.16 OEU12500.1 - 3.6 6.3 22.2 0.1 11.4 2.9 2.3 2 0 0 2 2 2 0 Androgen receptor RNA_pol_Rbc25 PF08292.12 OEU12500.1 - 3.6 7.8 6.4 2.3 8.4 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 TFIIA PF03153.13 OEU12500.1 - 5.1 7.0 22.8 0.18 11.7 1.3 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PIEZO PF15917.5 OEU12500.1 - 6.5 6.2 9.5 2.8 7.4 2.3 2.2 2 0 0 2 2 2 0 Piezo HA PF03457.14 OEU12501.1 - 7.7e-64 211.9 2.6 3.2e-16 59.4 0.0 4.1 4 0 0 4 4 4 4 Helicase associated domain DUF4050 PF13259.6 OEU12501.1 - 0.0031 17.9 0.3 0.0082 16.5 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) T_cell_tran_alt PF15128.6 OEU12501.1 - 0.012 15.4 3.0 0.96 9.3 0.4 2.7 2 1 0 2 2 2 0 T-cell leukemia translocation-altered PRK PF00485.18 OEU12501.1 - 0.046 13.4 0.2 0.12 12.1 0.0 1.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF3105 PF11303.8 OEU12501.1 - 0.059 13.5 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) PMR5N PF14416.6 OEU12501.1 - 0.12 12.7 0.3 1.2e+02 3.0 0.0 4.1 4 0 0 4 4 4 0 PMR5 N terminal Domain ATP-grasp_3 PF02655.14 OEU12502.1 - 1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PPDK_N PF01326.19 OEU12502.1 - 0.00071 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ATP-grasp PF02222.22 OEU12502.1 - 0.029 14.0 0.0 0.38 10.3 0.0 2.2 1 1 0 1 1 1 0 ATP-grasp domain DUF448 PF04296.13 OEU12502.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) CPSase_L_D2 PF02786.17 OEU12502.1 - 0.077 12.5 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 OEU12502.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Sugar_tr PF00083.24 OEU12503.1 - 3.2e-67 227.3 23.1 1.1e-48 166.3 6.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OEU12503.1 - 4e-20 72.0 29.3 3.3e-19 69.0 11.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OEU12503.1 - 0.22 10.3 13.9 0.14 11.0 3.9 3.9 2 2 1 3 3 3 0 MFS_1 like family Orf78 PF06024.12 OEU12505.1 - 2.8 8.3 11.3 2.6 8.4 0.1 3.0 2 1 1 3 3 3 0 Orf78 (ac78) DUF4834 PF16118.5 OEU12505.1 - 3.9 8.5 0.0 3.9 8.5 0.0 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4834) Met_10 PF02475.16 OEU12507.1 - 3.5e-22 79.1 2.2 1.1e-18 67.7 0.0 3.4 3 2 0 3 3 3 2 Met-10+ like-protein RPOL_N PF14700.6 OEU12507.1 - 0.18 11.2 3.0 0.094 12.1 0.3 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal BCD PF15461.6 OEU12508.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Alpha-amylase_N PF02903.14 OEU12509.1 - 0.02 15.0 0.1 5.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Alpha amylase, N-terminal ig-like domain Trypan_PARP PF05887.11 OEU12509.1 - 0.41 10.6 15.5 1.3 9.0 15.5 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF563 PF04577.14 OEU12510.1 - 1.3e-13 51.6 2.0 3e-12 47.1 0.4 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Apocytochr_F_N PF16639.5 OEU12510.1 - 0.069 13.4 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 Apocytochrome F, N-terminal TAS2R PF05296.13 OEU12510.1 - 0.69 9.0 4.1 1.9 7.5 4.1 1.7 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) TIC20 PF16166.5 OEU12511.1 - 4.7e-12 46.1 0.0 6.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like EF-hand_1 PF00036.32 OEU12511.1 - 2.8e-10 39.0 0.7 6.9e-06 25.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU12511.1 - 5.5e-09 36.3 0.8 1.2e-08 35.3 0.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU12511.1 - 1.5e-08 33.9 1.2 9.5e-05 22.0 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU12511.1 - 4.3e-08 32.3 1.8 2.8e-05 23.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OEU12511.1 - 2.2e-06 27.4 6.0 3.4e-05 23.6 1.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OEU12511.1 - 0.0035 17.6 0.1 0.0067 16.7 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain ArAE_1_C PF11728.8 OEU12511.1 - 0.0051 16.8 0.3 0.011 15.7 0.3 1.5 1 0 0 1 1 1 1 Putative aromatic acid exporter C-terminal domain EF-hand_10 PF14788.6 OEU12511.1 - 0.079 12.8 0.5 0.26 11.2 0.1 1.9 1 1 1 2 2 2 0 EF hand AAA_14 PF13173.6 OEU12511.1 - 0.082 12.9 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 AAA domain FliN_N PF16973.5 OEU12511.1 - 0.1 12.5 1.2 0.33 10.8 1.2 1.9 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal Asp-Al_Ex PF06826.12 OEU12511.1 - 0.22 11.3 3.4 0.23 11.2 2.0 1.6 1 1 1 2 2 2 0 Predicted Permease Membrane Region CRA_rpt PF07046.11 OEU12511.1 - 9.9 6.4 11.5 1.2 9.4 1.4 2.4 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat COQ9 PF08511.11 OEU12512.1 - 0.011 15.5 0.4 0.033 14.0 0.0 2.0 2 0 0 2 2 2 0 COQ9 TPR_2 PF07719.17 OEU12512.1 - 0.045 13.9 0.5 18 5.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Trimer_CC PF08954.11 OEU12513.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif TSC22 PF01166.18 OEU12513.1 - 0.16 12.3 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Erv26 PF04148.13 OEU12513.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 ECSIT_C PF14784.6 OEU12514.1 - 0.026 14.9 0.3 0.026 14.9 0.3 3.0 3 2 1 4 4 4 0 C-terminal domain of the ECSIT protein DUF5383 PF17355.2 OEU12514.1 - 0.16 12.4 0.2 0.16 12.4 0.2 3.6 4 1 1 5 5 5 0 Family of unknown function (DUF5383) DUF2973 PF11189.8 OEU12514.1 - 0.29 11.2 1.0 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF4834 PF16118.5 OEU12514.1 - 0.83 10.7 20.0 1.5 9.8 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) MFS_1 PF07690.16 OEU12515.1 - 4.2e-53 180.5 22.9 1.3e-44 152.6 10.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU12515.1 - 3.3e-09 36.1 3.1 3.3e-09 36.1 3.1 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 OEU12515.1 - 4.2e-07 29.2 8.4 0.00028 19.9 0.1 3.4 3 1 1 4 4 4 3 MFS_1 like family MFS_3 PF05977.13 OEU12515.1 - 0.0001 20.8 15.1 0.0045 15.5 4.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 OEU12515.1 - 0.00039 19.3 0.6 0.00039 19.3 0.6 2.2 2 1 0 2 2 2 1 LacY proton/sugar symporter P2X_receptor PF00864.19 OEU12515.1 - 0.027 13.5 0.3 0.043 12.9 0.3 1.2 1 0 0 1 1 1 0 ATP P2X receptor MFS_4 PF06779.14 OEU12515.1 - 0.034 13.4 23.1 0.029 13.7 9.2 3.4 2 2 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB Metallophos PF00149.28 OEU12516.1 - 1.4e-07 32.3 1.2 1.4e-07 32.3 1.2 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 OEU12516.1 - 0.0014 18.9 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Selenoprotein_S PF06936.11 OEU12516.1 - 0.22 11.3 2.1 0.64 9.8 0.2 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF4834 PF16118.5 OEU12516.1 - 3.7 8.6 14.4 6.4 7.8 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Myc_N PF01056.18 OEU12516.1 - 4.6 7.1 16.3 0.019 14.9 5.8 2.3 3 0 0 3 3 3 0 Myc amino-terminal region DUF3439 PF11921.8 OEU12517.1 - 0.44 10.5 3.6 1 9.4 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAP PF02037.27 OEU12518.1 - 9.7e-09 34.8 2.0 1.6e-08 34.1 0.4 2.1 2 0 0 2 2 2 1 SAP domain Glyco_tranf_2_4 PF13704.6 OEU12518.1 - 1.5e-05 25.4 5.8 0.0044 17.5 5.8 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 HeH PF12949.7 OEU12518.1 - 0.00018 21.1 1.6 0.00038 20.1 1.6 1.5 1 0 0 1 1 1 1 HeH/LEM domain LMBR1 PF04791.16 OEU12518.1 - 1.3 7.8 4.8 2.5 6.9 4.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein GPCR_chapero_1 PF11904.8 OEU12518.1 - 8.3 5.7 10.7 20 4.5 10.7 1.7 1 1 0 1 1 1 0 GPCR-chaperone Mto2_bdg PF12808.7 OEU12519.1 - 0.11 12.8 7.8 0.37 11.1 7.8 1.9 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TCR_zetazeta PF11628.8 OEU12519.1 - 0.13 12.0 0.4 0.22 11.2 0.4 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain DUF3810 PF12725.7 OEU12519.1 - 0.45 9.8 1.7 0.84 8.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) zf-RING_2 PF13639.6 OEU12521.1 - 5.3e-07 29.9 2.7 9.8e-07 29.0 2.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU12521.1 - 2.1e-05 24.2 8.7 3.9e-05 23.3 8.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OEU12521.1 - 8.3e-05 22.6 0.3 0.00014 21.8 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OEU12521.1 - 0.00017 21.4 2.9 0.00017 21.4 1.2 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Zf_RING PF16744.5 OEU12521.1 - 0.00046 20.2 1.2 0.0008 19.5 1.2 1.3 1 0 0 1 1 1 1 KIAA1045 RING finger zf-rbx1 PF12678.7 OEU12521.1 - 0.0012 19.1 3.5 0.0037 17.5 3.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU12521.1 - 0.0018 18.3 1.8 0.0042 17.1 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU12521.1 - 0.0042 16.9 3.2 0.0042 16.9 3.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Casc1 PF12366.8 OEU12521.1 - 0.0047 16.5 0.5 0.0065 16.0 0.5 1.2 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 Zn_ribbon_17 PF17120.5 OEU12521.1 - 0.0048 16.5 3.7 0.009 15.6 3.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 OEU12521.1 - 0.0055 16.5 3.8 0.0055 16.5 3.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OEU12521.1 - 0.02 15.1 0.4 0.042 14.0 0.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU12521.1 - 0.054 13.5 2.8 0.095 12.7 2.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 OEU12521.1 - 0.078 12.9 5.3 0.046 13.6 3.2 1.7 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 OEU12522.1 - 1.1e-08 35.2 4.1 2.7e-08 34.0 4.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU12522.1 - 4.5e-06 26.3 6.5 4.5e-06 26.3 6.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OEU12522.1 - 0.0001 22.2 4.7 0.0006 19.8 4.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OEU12522.1 - 0.00014 21.7 0.9 0.00014 21.7 0.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 OEU12522.1 - 0.0029 17.4 2.2 0.0029 17.4 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 OEU12522.1 - 0.0036 17.4 5.5 0.0082 16.2 5.5 1.7 1 1 0 1 1 1 1 KIAA1045 RING finger zf-rbx1 PF12678.7 OEU12522.1 - 0.0039 17.4 7.3 0.013 15.8 6.5 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU12522.1 - 0.0042 16.9 5.4 0.0042 16.9 5.4 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OEU12522.1 - 0.0045 16.6 2.5 0.012 15.2 2.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OEU12522.1 - 0.0062 16.5 1.2 0.0062 16.5 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger PHD PF00628.29 OEU12522.1 - 0.023 14.6 4.2 0.062 13.2 4.2 1.8 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OEU12522.1 - 0.03 14.5 5.1 0.065 13.4 5.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU12522.1 - 0.06 13.3 8.2 0.04 13.9 5.8 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU12522.1 - 2.8 7.8 8.1 12 5.9 8.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mis14 PF08641.12 OEU12523.1 - 0.028 14.7 1.4 0.056 13.8 1.4 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like BBS2_C PF14782.6 OEU12524.1 - 0.032 13.0 1.1 0.062 12.1 1.1 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal MHC2-interact PF09307.10 OEU12524.1 - 0.06 13.4 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 CLIP, MHC2 interacting TM1506 PF08973.10 OEU12524.1 - 0.061 13.0 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) Clr2 PF10383.9 OEU12525.1 - 0.053 14.3 1.3 0.1 13.4 1.3 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 zinc_ribbon_2 PF13240.6 OEU12525.1 - 0.12 12.1 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 OEU12525.1 - 0.13 12.3 1.7 0.3 11.2 1.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S2 PF00318.20 OEU12525.1 - 2.1 7.6 6.2 0.14 11.3 0.3 2.2 3 0 0 3 3 3 0 Ribosomal protein S2 PFEMP PF03011.15 OEU12525.1 - 6.9 7.3 9.5 0.14 12.8 1.4 2.3 3 0 0 3 3 3 0 PFEMP DBL domain Alpha_GJ PF03229.13 OEU12527.1 - 1.8 9.1 14.9 0.79 10.3 1.1 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J zf-RING_2 PF13639.6 OEU12528.1 - 9.1e-09 35.5 4.8 1.8e-08 34.6 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU12528.1 - 2e-06 27.4 6.5 3.7e-06 26.6 6.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_1 PF14446.6 OEU12528.1 - 0.00015 21.6 1.0 0.00015 21.6 1.0 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 OEU12528.1 - 0.00026 21.0 3.9 0.0011 19.0 3.9 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OEU12528.1 - 0.00092 19.0 2.4 0.00092 19.0 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 OEU12528.1 - 0.0028 17.7 4.4 0.0051 16.9 4.4 1.4 1 0 0 1 1 1 1 KIAA1045 RING finger zf-rbx1 PF12678.7 OEU12528.1 - 0.0028 17.9 5.6 0.0082 16.4 5.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU12528.1 - 0.0034 17.2 5.9 0.0046 16.8 4.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU12528.1 - 0.01 15.7 5.6 0.012 15.6 4.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU12528.1 - 0.012 15.6 1.5 0.012 15.6 1.5 2.3 3 0 0 3 3 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OEU12528.1 - 0.023 14.3 2.1 0.047 13.3 2.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OEU12528.1 - 0.093 12.6 4.2 0.21 11.5 4.2 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OEU12528.1 - 0.099 12.8 4.9 0.21 11.8 4.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 OEU12528.1 - 3.4 7.6 8.1 9.6 6.2 8.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AIM24 PF01987.17 OEU12529.1 - 1.1e-39 136.3 0.1 1.3e-39 136.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 KRTAP PF11759.8 OEU12529.1 - 0.056 14.0 3.5 0.056 14.0 3.5 2.5 3 0 0 3 3 3 0 Keratin-associated matrix BAG PF02179.16 OEU12531.1 - 0.0036 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 BAG domain CzcE PF16986.5 OEU12531.1 - 0.041 14.2 0.2 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Heavy-metal resistance protein CzcE Macoilin PF09726.9 OEU12531.1 - 0.073 11.6 3.1 0.098 11.2 3.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF664 PF04978.12 OEU12531.1 - 0.13 12.7 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Mito_fiss_reg PF05308.11 OEU12531.1 - 0.85 9.7 10.7 0.12 12.5 6.2 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator FKBP_C PF00254.28 OEU12533.1 - 1.3e-08 35.1 0.1 2.1e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Serglycin PF04360.12 OEU12534.1 - 0.0023 17.9 0.9 0.0023 17.9 0.9 1.8 2 0 0 2 2 2 1 Serglycin FancD2 PF14631.6 OEU12535.1 - 1.5 6.2 8.1 2.2 5.6 8.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF3494 PF11999.8 OEU12536.1 - 3.7e-54 183.5 16.8 4.6e-54 183.2 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) TFIIA PF03153.13 OEU12536.1 - 0.0083 16.2 24.0 0.011 15.8 24.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4604 PF15377.6 OEU12536.1 - 0.86 10.0 17.7 1.3 9.5 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Peptidase_S8 PF00082.22 OEU12538.1 - 2.7e-20 72.8 2.1 3.2e-13 49.6 0.2 3.0 2 1 0 2 2 2 2 Subtilase family P_proprotein PF01483.20 OEU12538.1 - 3.7e-13 49.3 0.4 9e-13 48.1 0.4 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Fasciclin PF02469.22 OEU12538.1 - 3.8e-13 49.8 0.0 6.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain PSI PF01437.25 OEU12538.1 - 0.096 13.2 8.2 0.34 11.5 8.2 2.0 1 0 0 1 1 1 0 Plexin repeat WD40 PF00400.32 OEU12539.1 - 4.2e-31 106.5 14.4 1.1e-07 32.4 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU12539.1 - 4.9e-10 39.6 0.4 0.034 14.4 0.0 5.5 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU12539.1 - 1.4e-05 24.2 0.0 0.34 9.8 0.1 3.3 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OEU12539.1 - 0.0011 19.4 1.1 2.5 8.7 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 OEU12539.1 - 0.0054 16.1 2.7 0.2 11.0 0.1 3.4 2 2 2 4 4 4 1 WD40-like domain Phytase PF02333.15 OEU12539.1 - 0.02 13.9 0.2 0.049 12.6 0.2 1.6 1 0 0 1 1 1 0 Phytase Peptidase_S10 PF00450.22 OEU12540.1 - 1e-73 249.1 0.3 1.8e-73 248.4 0.3 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase zf-HC5HC2H PF13771.6 OEU12540.1 - 0.018 15.2 0.4 0.04 14.2 0.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Cwf_Cwc_15 PF04889.12 OEU12540.1 - 5.7 6.6 6.2 13 5.5 6.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase_Tyr PF07714.17 OEU12541.1 - 0.042 13.1 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4064 PF13273.6 OEU12542.1 - 0.039 14.2 1.1 7.7 6.8 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) KH_10 PF17905.1 OEU12542.1 - 0.16 12.4 4.5 7.9 7.0 0.2 2.7 2 1 0 2 2 2 0 GLD-3 KH domain 5 CoA_binding_2 PF13380.6 OEU12543.1 - 1.8e-33 115.5 0.0 2.1e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 OEU12543.1 - 2.5e-05 24.8 0.0 4.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain PAP2_3 PF14378.6 OEU12544.1 - 0.0038 17.0 0.3 0.0047 16.6 0.3 1.1 1 0 0 1 1 1 1 PAP2 superfamily CCB1 PF12046.8 OEU12544.1 - 0.29 10.4 0.6 0.35 10.2 0.6 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Chorion_2 PF03964.15 OEU12547.1 - 6 7.8 8.6 6.1 7.8 1.7 2.9 2 0 0 2 2 2 0 Chorion family 2 M_domain PF12938.7 OEU12548.1 - 1.9 8.3 10.4 0.52 10.1 6.8 1.9 2 0 0 2 2 2 0 M domain of GW182 CI-B14_5a PF07347.12 OEU12548.1 - 2 8.3 15.7 0.054 13.4 1.0 4.1 4 1 0 4 4 4 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) CAP_N PF01213.19 OEU12549.1 - 0.0087 15.6 2.2 0.0087 15.6 2.2 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OEU12549.1 - 1.4 8.9 6.7 0.46 10.5 2.6 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator GREB1 PF15782.5 OEU12550.1 - 0.34 8.0 13.6 0.49 7.5 13.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 OEU12551.1 - 3.8 6.2 8.3 4.3 6.0 8.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 YfhO PF09586.10 OEU12551.1 - 5.9 5.0 8.3 6.7 4.8 8.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1951 PF09188.10 OEU12552.1 - 0.45 10.5 3.4 0.22 11.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) DUF2799 PF10973.8 OEU12552.1 - 8.1 6.9 8.6 2.5 8.6 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2799) Peptidase_M14 PF00246.24 OEU12553.1 - 3.6e-16 59.8 9.4 7.8e-15 55.4 0.1 3.5 2 1 1 3 3 3 2 Zinc carboxypeptidase Dicty_CAD PF05720.12 OEU12553.1 - 0.0091 16.0 0.2 0.032 14.2 0.2 1.9 1 0 0 1 1 1 1 Cell-cell adhesion domain AstE_AspA PF04952.14 OEU12553.1 - 0.04 13.0 0.2 0.095 11.8 0.2 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF285 PF03382.14 OEU12554.1 - 1e-51 173.8 16.0 7.3e-28 96.8 1.5 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 BssS PF13991.6 OEU12554.1 - 0.0056 16.7 1.6 5.8 7.1 0.1 3.3 2 1 1 3 3 3 2 BssS protein family CoA_binding_2 PF13380.6 OEU12555.1 - 2.6e-07 31.1 0.0 4.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 CoA binding domain DUF3984 PF13136.6 OEU12557.1 - 0.0032 16.9 13.8 0.0041 16.6 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) PRC2_HTH_1 PF18118.1 OEU12557.1 - 0.033 15.0 4.7 0.033 15.0 4.7 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain BT1 PF03092.16 OEU12557.1 - 0.05 11.8 0.9 0.064 11.5 0.9 1.1 1 0 0 1 1 1 0 BT1 family Suf PF05843.14 OEU12557.1 - 0.058 13.4 17.1 0.069 13.1 17.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5523 PF17661.1 OEU12557.1 - 0.35 10.5 13.3 0.45 10.2 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Presenilin PF01080.17 OEU12557.1 - 0.72 8.6 13.6 0.86 8.3 13.6 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 OEU12557.1 - 0.79 8.8 22.2 0.99 8.5 22.2 1.2 1 0 0 1 1 1 0 SprA-related family Orf78 PF06024.12 OEU12557.1 - 1.6 9.1 11.4 1.5 9.2 5.9 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Peptidase_S49_N PF08496.10 OEU12557.1 - 3 7.9 10.1 0.84 9.7 7.6 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RNA_pol_Rbc25 PF08292.12 OEU12557.1 - 4.3 7.6 12.4 1.4 9.1 9.0 1.8 1 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 Folate_carrier PF01770.18 OEU12557.1 - 8.7 5.0 13.8 1 8.0 9.4 1.6 1 1 1 2 2 2 0 Reduced folate carrier Tmem26 PF09772.9 OEU12557.1 - 9.4 5.5 9.0 2.4 7.4 5.7 1.7 1 1 1 2 2 2 0 Transmembrane protein 26 3Beta_HSD PF01073.19 OEU12560.1 - 0.045 12.7 0.0 0.046 12.7 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Antimicrobial_1 PF08018.11 OEU12562.1 - 1.6 8.9 4.0 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Frog antimicrobial peptide DUF167 PF02594.16 OEU12564.1 - 0.0017 18.4 0.0 21 5.3 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised ACR, YggU family COG1872 DUF1805 PF08827.11 OEU12564.1 - 0.11 12.9 2.4 23 5.4 0.1 4.0 1 1 3 5 5 5 0 Domain of unknown function (DUF1805) MOZART2 PF12926.7 OEU12564.1 - 0.11 12.1 1.0 23 4.7 0.0 3.7 2 1 2 4 4 4 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF4061 PF13270.6 OEU12564.1 - 0.29 11.5 5.5 5.1 7.5 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4061) Trp_repressor PF01371.19 OEU12564.1 - 0.5 10.5 2.5 18 5.5 0.1 3.9 2 2 4 6 6 6 0 Trp repressor protein Endotoxin_C2 PF18449.1 OEU12564.1 - 0.6 10.5 6.2 83 3.6 0.1 4.7 5 1 0 5 5 5 0 Delta endotoxin DUF3450 PF11932.8 OEU12566.1 - 0.034 13.4 1.4 11 5.2 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) SPOB_ab PF14682.6 OEU12566.1 - 0.084 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Mer2 PF09074.10 OEU12566.1 - 0.47 10.2 8.0 0.09 12.6 0.6 3.0 2 1 1 3 3 3 0 Mer2 Dehydrin PF00257.19 OEU12567.1 - 0.081 13.5 6.3 3.9 8.0 0.2 2.2 2 0 0 2 2 2 0 Dehydrin Cys_rich_CPCC PF14206.6 OEU12570.1 - 0.29 11.0 3.8 0.22 11.3 0.9 2.1 1 1 1 2 2 2 0 Cysteine-rich CPCC DDE_Tnp_1_7 PF13843.6 OEU12571.1 - 8.7e-12 45.0 0.1 4.1e-09 36.2 0.1 2.2 2 0 0 2 2 2 2 Transposase IS4 Ribosomal_L28e PF01778.17 OEU12573.1 - 0.092 13.5 1.7 0.27 12.0 1.7 1.8 1 0 0 1 1 1 0 Ribosomal L28e protein family DDE_Tnp_1_7 PF13843.6 OEU12576.1 - 2.8e-15 56.5 0.0 3.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 AMH_N PF04709.12 OEU12579.1 - 0.062 12.2 0.4 0.11 11.3 0.4 1.3 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region STD1 PF17235.2 OEU12580.1 - 0.022 14.4 0.2 0.055 13.1 0.2 1.7 1 0 0 1 1 1 0 STD1/MTH1 VanY PF02557.17 OEU12580.1 - 0.049 13.4 0.2 0.24 11.2 0.1 2.2 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase GSDH PF07995.11 OEU12581.1 - 1.4e-06 27.9 1.0 3.7e-06 26.5 0.7 1.9 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase HZS_alpha PF18582.1 OEU12581.1 - 0.036 14.6 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain DUF4922 PF16269.5 OEU12582.1 - 0.11 12.2 0.0 0.46 10.2 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4922) Peptidase_M6 PF05547.11 OEU12583.1 - 8.2e-17 60.8 7.4 1.3e-16 60.1 6.4 1.7 1 1 1 2 2 2 1 Immune inhibitor A peptidase M6 Peptidase_M66 PF10462.9 OEU12583.1 - 0.00097 18.2 0.2 0.0018 17.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 OEU12583.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Matrixin Astacin PF01400.24 OEU12583.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 OEU12583.1 - 0.19 10.9 0.7 0.7 9.1 0.1 1.9 1 1 1 2 2 2 0 Met-zincin SMC_N PF02463.19 OEU12584.1 - 2e-69 233.4 0.0 3.7e-68 229.2 0.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OEU12584.1 - 7.1e-21 74.7 0.5 2.5e-20 72.9 0.5 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OEU12584.1 - 4.6e-11 43.1 6.5 3.9e-05 23.6 0.4 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OEU12584.1 - 9.9e-07 28.8 15.0 9.9e-07 28.8 15.0 4.7 2 2 1 3 3 1 1 AAA ATPase domain AAA_23 PF13476.6 OEU12584.1 - 3.1e-05 24.6 33.8 3.1e-05 24.6 33.8 6.7 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.6 OEU12584.1 - 6.1e-05 22.7 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain GldM_N PF12081.8 OEU12584.1 - 0.0083 16.2 13.4 0.0083 16.2 13.4 5.6 2 2 4 6 6 3 1 GldM N-terminal domain MEDS PF14417.6 OEU12584.1 - 0.016 15.0 0.8 0.07 13.0 0.8 2.1 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ABC_tran PF00005.27 OEU12584.1 - 0.035 14.6 0.1 0.035 14.6 0.1 6.6 5 1 1 6 6 6 0 ABC transporter YabA PF06156.13 OEU12584.1 - 0.051 14.2 0.4 0.051 14.2 0.4 7.3 4 2 2 6 6 6 0 Initiation control protein YabA Nup54 PF13874.6 OEU12584.1 - 2.2 8.4 47.5 0.53 10.4 9.0 5.6 3 1 2 5 5 5 0 Nucleoporin complex subunit 54 DUF3584 PF12128.8 OEU12584.1 - 2.2 5.7 76.4 0.95 6.9 23.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Vac14_Fig4_bd PF11916.8 OEU12585.1 - 2e-67 226.3 6.9 2e-67 226.3 6.9 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OEU12585.1 - 4.5e-45 152.2 0.0 2.6e-38 130.5 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OEU12585.1 - 5.8e-16 57.2 3.6 7.4e-05 22.7 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 OEU12585.1 - 8.6e-12 45.3 0.1 0.039 14.5 0.0 5.0 4 1 1 5 5 5 3 HEAT-like repeat Cnd1 PF12717.7 OEU12585.1 - 3.3e-11 43.5 2.5 9.6e-05 22.5 0.0 4.4 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OEU12585.1 - 8.2e-08 32.5 0.2 0.38 11.2 0.0 4.9 4 1 0 4 4 4 3 HEAT repeats CLASP_N PF12348.8 OEU12585.1 - 2.5e-07 30.5 0.4 0.014 14.9 0.0 4.8 4 1 0 5 5 5 1 CLASP N terminal Tti2 PF10521.9 OEU12585.1 - 0.0003 20.4 2.4 0.033 13.7 0.0 4.2 5 0 0 5 5 5 1 Tti2 family NopRA1 PF16201.5 OEU12585.1 - 0.0036 16.9 4.2 6.3 6.3 0.1 3.7 4 0 0 4 4 4 2 Nucleolar pre-ribosomal-associated protein 1 RasGEF_N_2 PF14663.6 OEU12585.1 - 0.0052 17.2 1.4 2.1 8.8 0.0 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 OEU12585.1 - 0.008 16.3 0.4 4.7 7.3 0.1 2.8 1 1 1 2 2 2 2 Parkin co-regulated protein RTP1_C1 PF10363.9 OEU12585.1 - 0.017 15.3 2.0 1.1 9.5 0.1 3.9 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 OEU12585.1 - 0.025 14.5 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) WVELL PF14043.6 OEU12585.1 - 0.039 13.8 1.7 2.3 8.1 0.1 3.1 3 0 0 3 3 3 0 WVELL protein MMS19_C PF12460.8 OEU12585.1 - 0.14 11.2 10.5 3.8 6.5 0.0 4.8 3 2 1 5 5 5 0 RNAPII transcription regulator C-terminal CS PF04969.16 OEU12586.1 - 5.4e-14 53.0 0.0 8.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 CS domain TBCC PF07986.12 OEU12588.1 - 1.3e-22 79.8 0.1 3.8e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 OEU12588.1 - 0.00073 19.2 0.4 0.0013 18.4 0.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Sulfatase PF00884.23 OEU12589.1 - 5e-38 131.2 0.3 7.6e-38 130.6 0.3 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OEU12589.1 - 4.2e-09 36.6 0.0 9.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OEU12589.1 - 1.1e-05 25.2 0.3 0.099 12.2 0.1 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase CS PF04969.16 OEU12589.1 - 0.012 16.7 0.3 0.021 15.8 0.3 1.5 1 0 0 1 1 1 0 CS domain TIC20 PF16166.5 OEU12590.1 - 3.7e-13 49.6 0.1 4.8e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like Methyltransf_25 PF13649.6 OEU12591.1 - 6.4e-05 23.6 0.0 0.0001 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU12591.1 - 0.0001 22.2 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 OEU12591.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_4 PF02390.17 OEU12591.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 OEU12591.1 - 0.00019 22.1 0.0 0.00036 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OEU12591.1 - 0.00025 21.0 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OEU12591.1 - 0.0003 20.2 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OEU12591.1 - 0.00054 20.5 0.0 0.00086 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU12591.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 OEU12591.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 OEU12591.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 OEU12591.1 - 0.07 12.7 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 OEU12591.1 - 0.07 12.2 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 OEU12591.1 - 0.19 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 OEU12592.1 - 3.1e-66 222.4 0.0 1.5e-65 220.1 0.0 2.1 2 1 1 3 3 3 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OEU12592.1 - 1.9e-17 62.9 0.1 3.5e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OEU12592.1 - 0.0002 22.0 0.0 0.00042 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU12592.1 - 0.045 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OEU12592.1 - 0.09 13.5 0.0 0.22 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain UPF0167 PF03691.14 OEU12593.1 - 0.089 12.6 0.5 0.2 11.4 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) PHD PF00628.29 OEU12593.1 - 0.1 12.5 4.0 0.19 11.6 4.0 1.4 1 0 0 1 1 1 0 PHD-finger Asp_Glu_race PF01177.22 OEU12595.1 - 2.8e-09 37.2 0.0 0.0024 17.8 0.0 2.8 2 1 0 2 2 2 2 Asp/Glu/Hydantoin racemase Glyco_hydro_125 PF06824.11 OEU12596.1 - 3.2e-85 286.5 0.1 3.6e-85 286.3 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) HATPase_c PF02518.26 OEU12598.1 - 9.4e-15 55.1 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OEU12598.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 OEU12598.1 - 0.041 14.2 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 GAF domain Methyltransf_12 PF08242.12 OEU12599.1 - 0.03 15.1 1.9 0.24 12.1 0.5 2.7 2 1 0 2 2 2 0 Methyltransferase domain Alpha_kinase PF02816.18 OEU12600.1 - 6.9e-23 81.7 0.3 1.1e-13 51.8 0.5 2.1 1 1 1 2 2 2 2 Alpha-kinase family Stc1 PF12898.7 OEU12600.1 - 1.6 9.4 7.9 0.29 11.7 3.3 2.0 2 0 0 2 2 2 0 Stc1 domain Ank_3 PF13606.6 OEU12601.1 - 0.029 14.9 0.1 5.1 8.0 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Acetyltransf_1 PF00583.25 OEU12602.1 - 6.9e-11 42.4 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU12602.1 - 3.9e-05 24.0 0.0 7.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU12602.1 - 9.5e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU12602.1 - 0.016 15.3 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU12602.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Hydrolase_4 PF12146.8 OEU12603.1 - 3.5e-07 29.7 0.0 0.00019 20.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU12603.1 - 0.00067 19.4 0.1 0.0066 16.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF829 PF05705.14 OEU12603.1 - 0.0072 16.3 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) zf-RING_11 PF17123.5 OEU12603.1 - 0.14 11.9 0.4 0.3 10.9 0.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger ACPS PF01648.20 OEU12606.1 - 4.3e-08 33.3 0.0 1.4e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily C-C_Bond_Lyase PF15617.6 OEU12607.1 - 0.0049 16.1 0.0 0.0055 15.9 0.0 1.1 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold Pre-PUA PF17832.1 OEU12608.1 - 1.5e-23 83.3 0.1 2.4e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OEU12608.1 - 2.5e-15 56.2 0.0 5.6e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 PUA domain ATP-grasp_6 PF18419.1 OEU12608.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp-like domain Sulfate_transp PF00916.20 OEU12609.1 - 8.8e-22 77.4 20.0 1.2e-20 73.7 18.8 2.6 2 1 0 2 2 2 1 Sulfate permease family KbaA PF14089.6 OEU12610.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation Nucleoporin_FG PF13634.6 OEU12613.1 - 1.6 9.6 10.2 8.8 7.3 5.4 2.4 2 0 0 2 2 2 0 Nucleoporin FG repeat region adh_short PF00106.25 OEU12614.1 - 2.6e-24 85.8 0.0 3.4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU12614.1 - 4e-22 78.9 0.0 5.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU12614.1 - 0.0038 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain AAA PF00004.29 OEU12615.1 - 1.3e-38 132.4 0.0 2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU12615.1 - 1.8e-10 40.5 0.0 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OEU12615.1 - 2.4e-08 33.8 0.0 5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 OEU12615.1 - 4.5e-07 29.7 0.0 8.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OEU12615.1 - 2.7e-06 27.4 0.5 1.4e-05 25.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OEU12615.1 - 9.1e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OEU12615.1 - 0.00011 22.7 0.4 0.00047 20.6 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU12615.1 - 0.00015 22.0 0.5 0.083 13.2 0.1 2.8 1 1 2 3 3 3 1 AAA domain AAA_25 PF13481.6 OEU12615.1 - 0.00054 19.6 0.6 0.62 9.6 0.1 3.0 1 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 OEU12615.1 - 0.00055 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 OEU12615.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain Bac_DnaA PF00308.18 OEU12615.1 - 0.0021 18.0 0.0 0.0057 16.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_14 PF13173.6 OEU12615.1 - 0.0088 16.1 0.0 0.044 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 OEU12615.1 - 0.011 15.2 0.1 14 5.1 0.0 3.1 2 1 0 3 3 3 0 Bacterial TniB protein Sigma54_activat PF00158.26 OEU12615.1 - 0.012 15.3 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 OEU12615.1 - 0.015 14.7 0.4 1 8.6 0.1 2.2 1 1 1 2 2 2 0 KaiC IstB_IS21 PF01695.17 OEU12615.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 OEU12615.1 - 0.034 14.7 0.0 0.062 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OEU12615.1 - 0.041 13.3 0.1 0.095 12.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 OEU12615.1 - 0.042 12.9 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 OEU12615.1 - 0.049 12.9 0.1 0.092 12.0 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OEU12615.1 - 0.081 12.4 0.0 0.25 10.8 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Toxin_trans PF07952.12 OEU12615.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF815 PF05673.13 OEU12615.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 OEU12615.1 - 0.13 11.6 0.1 4 6.8 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Sigma54_activ_2 PF14532.6 OEU12615.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 OEU12615.1 - 0.14 11.9 0.3 0.3 10.8 0.3 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU12615.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Troponin PF00992.20 OEU12616.1 - 0.51 10.6 3.4 0.72 10.2 3.4 1.2 1 0 0 1 1 1 0 Troponin ENTH PF01417.20 OEU12617.1 - 3.3e-07 30.4 0.0 9.4e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 ENTH domain MIOX PF05153.15 OEU12618.1 - 7.7e-38 130.5 0.2 4e-37 128.1 0.2 1.8 1 1 0 1 1 1 1 Myo-inositol oxygenase LRR_4 PF12799.7 OEU12619.1 - 3.4e-05 24.1 11.0 0.0051 17.2 0.3 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU12619.1 - 0.17 11.7 5.1 11 5.8 0.2 3.8 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 OEU12619.1 - 2.4 9.0 11.2 9 7.3 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat UPF0176_N PF17773.1 OEU12620.1 - 1e-12 48.2 0.1 2.1e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 OEU12620.1 - 1.2e-08 35.2 4.6 4.5e-08 33.3 4.6 2.0 1 1 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 OEU12620.1 - 3.4e-05 24.3 0.0 0.00075 20.0 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain DUF501 PF04417.12 OEU12621.1 - 7.5e-26 90.6 0.0 4.4e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF501) LIN37 PF15306.6 OEU12622.1 - 8.7e-06 26.0 0.7 8.7e-06 26.0 0.7 2.0 2 1 0 2 2 2 1 LIN37 zf-MYND PF01753.18 OEU12623.1 - 2.6e-05 24.2 17.2 2.6e-05 24.2 17.2 1.9 2 0 0 2 2 2 1 MYND finger Vps62 PF06101.11 OEU12626.1 - 0.054 11.8 0.0 0.075 11.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 LRR_4 PF12799.7 OEU12627.1 - 0.005 17.2 15.2 1 9.9 0.3 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) Mon1 PF03164.14 OEU12627.1 - 0.016 14.3 0.4 0.026 13.6 0.4 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 LRR_1 PF00560.33 OEU12627.1 - 0.034 14.7 14.2 5.3 8.0 0.5 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 OEU12627.1 - 0.21 11.3 3.4 38 4.1 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat Evr1_Alr PF04777.13 OEU12628.1 - 0.036 14.5 1.0 0.1 13.1 0.6 1.9 1 1 0 1 1 1 0 Erv1 / Alr family DUF4748 PF15932.5 OEU12628.1 - 0.047 13.4 0.3 0.11 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) LRR_6 PF13516.6 OEU12629.1 - 7.1e-18 63.1 14.5 0.0015 18.4 0.2 8.4 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 OEU12629.1 - 2.5e-08 34.1 11.1 0.024 15.0 0.1 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) PhyH PF05721.13 OEU12629.1 - 2.1e-07 31.4 1.3 5.4e-07 30.1 1.3 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_8 PF13855.6 OEU12629.1 - 0.00013 21.7 11.6 3.9 7.3 1.3 6.0 5 2 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 OEU12629.1 - 0.0093 16.4 9.7 41 5.3 0.1 7.1 7 0 0 7 7 7 0 Leucine Rich Repeat Mito_carr PF00153.27 OEU12630.1 - 2.6e-16 59.3 0.3 0.00023 21.0 0.0 5.0 4 1 1 5 5 5 4 Mitochondrial carrier protein Lig_chan PF00060.26 OEU12634.1 - 7.9e-09 35.5 0.1 2.3e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OEU12634.1 - 1.4e-06 28.0 0.0 3.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 IFT46_B_C PF12317.8 OEU12634.1 - 0.11 12.2 1.4 0.22 11.2 1.4 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal CKS PF01111.19 OEU12635.1 - 3.8e-35 120.0 0.2 5e-35 119.6 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DoxX PF07681.12 OEU12636.1 - 5.3e-13 49.4 3.7 5.3e-13 49.4 3.7 1.4 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 OEU12636.1 - 1.2e-05 25.3 0.1 2.2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 TQO small subunit DoxD DUF5493 PF17597.2 OEU12636.1 - 0.0081 16.4 3.6 0.015 15.5 3.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5493) DoxX_2 PF13564.6 OEU12636.1 - 0.016 15.3 0.2 0.03 14.4 0.2 1.5 1 0 0 1 1 1 0 DoxX-like family ERO1 PF04137.15 OEU12637.1 - 1.7e-47 162.4 0.1 3.4e-46 158.1 0.1 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HLH PF00010.26 OEU12638.1 - 4.5e-09 36.1 0.8 1.5e-08 34.5 0.4 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_8 PF13188.7 OEU12638.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 OEU12638.1 - 0.07 13.1 0.1 0.35 10.9 0.0 2.2 2 1 1 3 3 3 0 PAS fold PAS_9 PF13426.7 OEU12638.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain Amidase PF01425.21 OEU12639.1 - 1.6e-81 274.6 0.3 3.7e-67 227.3 1.2 3.2 2 1 0 2 2 2 2 Amidase zf-RING_2 PF13639.6 OEU12640.1 - 2.2e-06 27.9 15.4 0.00014 22.2 0.9 3.3 3 0 0 3 3 3 3 Ring finger domain zf-rbx1 PF12678.7 OEU12640.1 - 0.00013 22.1 4.0 0.00013 22.1 4.0 3.2 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU12640.1 - 0.0002 21.3 0.1 0.0002 21.3 0.1 3.3 3 0 0 3 3 3 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OEU12640.1 - 0.0023 17.5 0.9 0.0023 17.5 0.9 2.6 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OEU12640.1 - 0.0032 17.3 0.9 0.0032 17.3 0.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU12640.1 - 0.0045 16.7 3.7 0.0045 16.7 3.7 2.7 3 0 0 3 3 2 2 RING-like zinc finger FANCL_C PF11793.8 OEU12640.1 - 0.0058 16.8 4.5 0.17 12.1 0.2 3.0 3 0 0 3 3 3 1 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU12640.1 - 0.006 16.5 5.1 0.006 16.5 5.1 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU12640.1 - 0.0071 16.2 0.2 0.0071 16.2 0.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU12640.1 - 0.017 15.1 9.0 0.023 14.7 0.8 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OEU12640.1 - 0.28 11.1 12.7 3.5 7.6 0.7 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU12640.1 - 1.1 9.4 9.8 2 8.7 0.2 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Secretin_N_2 PF07655.13 OEU12640.1 - 4.4 7.9 8.4 8.6 7.0 0.5 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain MFS_1 PF07690.16 OEU12641.1 - 2.2e-08 33.5 20.5 4.4e-06 25.9 2.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DDRGK PF09756.9 OEU12642.1 - 2.7e-19 69.5 19.2 2.7e-19 69.5 19.2 2.1 2 0 0 2 2 2 1 DDRGK domain PCI PF01399.27 OEU12642.1 - 0.0026 18.2 0.1 0.0079 16.7 0.1 1.8 1 0 0 1 1 1 1 PCI domain TFIIA PF03153.13 OEU12642.1 - 0.024 14.6 18.7 0.03 14.3 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIG-S PF10510.9 OEU12642.1 - 0.032 13.1 9.4 0.051 12.4 9.4 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Draxin PF15550.6 OEU12642.1 - 2 8.2 17.0 2.9 7.7 17.0 1.1 1 0 0 1 1 1 0 Draxin DUF1676 PF07898.13 OEU12642.1 - 4.9 7.2 9.9 9.7 6.2 9.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF1295 PF06966.12 OEU12643.1 - 4.2e-13 49.4 0.8 4.2e-13 49.4 0.8 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OEU12643.1 - 6.7e-06 25.1 2.7 1.1e-05 24.4 2.7 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 OEU12643.1 - 3.8e-05 24.0 1.4 8.9e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 OEU12643.1 - 0.0035 17.3 1.2 0.0035 17.3 1.2 1.6 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Herpes_LMP1 PF05297.11 OEU12643.1 - 0.62 9.2 4.3 1.1 8.4 4.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FAD_binding_3 PF01494.19 OEU12644.1 - 1.5e-07 31.0 0.0 1.2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 OEU12644.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Nic96 PF04097.14 OEU12645.1 - 4.8e-38 131.0 0.0 7.8e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Nup93/Nic96 Tox-GHH PF15636.6 OEU12645.1 - 0.34 10.9 3.2 0.76 9.8 3.2 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin ABC1 PF03109.16 OEU12647.1 - 1.8e-14 53.9 0.0 3.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 OEU12647.1 - 0.0015 17.8 0.0 0.087 12.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OEU12647.1 - 0.015 14.7 0.1 0.46 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein kinase domain Complex1_LYR PF05347.15 OEU12649.1 - 0.017 15.1 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF3689 PF12463.8 OEU12650.1 - 4.7e-67 226.5 5.5 2.9e-52 177.9 0.3 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3689) DAGAT PF03982.13 OEU12652.1 - 1.2e-28 99.9 0.0 1.4e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LRS4 PF10422.9 OEU12653.1 - 0.58 9.7 7.6 0.81 9.2 7.6 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DNA_photolyase PF00875.18 OEU12654.1 - 0.022 14.8 0.1 0.1 12.6 0.1 2.1 1 1 0 1 1 1 0 DNA photolyase DUF4971 PF16341.5 OEU12654.1 - 0.13 12.1 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Androgen_recep PF02166.16 OEU12654.1 - 0.3 9.9 10.9 5 5.9 0.1 2.1 2 0 0 2 2 2 0 Androgen receptor DUF702 PF05142.12 OEU12654.1 - 0.6 10.6 7.4 0.51 10.8 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Pan_kinase PF03309.14 OEU12655.1 - 5.4e-19 68.9 0.0 1.2e-18 67.7 0.0 1.5 1 1 1 2 2 2 2 Type III pantothenate kinase PTP2 PF17022.5 OEU12655.1 - 0.12 11.9 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia AMP-binding PF00501.28 OEU12656.1 - 2.7e-81 273.3 0.0 3.7e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OEU12656.1 - 0.0043 17.4 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.6 OEU12656.1 - 0.04 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ACOX PF01756.19 OEU12659.1 - 3.7e-47 160.2 0.0 1e-46 158.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OEU12659.1 - 4.1e-29 101.7 0.0 7.6e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OEU12659.1 - 2.8e-10 40.2 0.0 9.3e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OEU12659.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 OEU12660.1 - 0.00061 18.8 30.0 0.003 16.5 14.5 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily ICMT PF04140.14 OEU12660.1 - 7.1 7.1 8.9 0.96 9.9 0.5 3.1 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Beta_propel PF09826.9 OEU12661.1 - 1.9e-68 231.6 0.4 2.2e-68 231.4 0.4 1.0 1 0 0 1 1 1 1 Beta propeller domain Methyltransf_5 PF01795.19 OEU12663.1 - 1.4e-68 231.7 0.0 9.8e-68 228.9 0.0 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_12 PF08242.12 OEU12663.1 - 0.047 14.4 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OEU12663.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNase_PH PF01138.21 OEU12664.1 - 1.3e-24 87.2 0.2 2e-24 86.6 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MFS_1 PF07690.16 OEU12666.1 - 3.3e-22 78.9 29.9 2.2e-20 72.9 16.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OEU12666.1 - 3.4e-06 25.7 13.1 2.8e-05 22.7 3.6 2.0 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 OEU12666.1 - 0.00047 19.1 15.3 0.0019 17.1 15.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter CENP-B_dimeris PF09026.10 OEU12666.1 - 0.66 10.4 0.1 0.66 10.4 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AvrPtoB_bdg PF16847.5 OEU12667.1 - 0.098 13.2 0.1 0.28 11.7 0.1 1.8 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain DUF1635 PF07795.11 OEU12667.1 - 6.6 6.5 17.8 3.8 7.3 12.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1635) PHD PF00628.29 OEU12668.1 - 9.6e-09 35.0 1.6 1.6e-08 34.3 1.6 1.4 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OEU12668.1 - 4.5e-06 26.1 1.3 4.5e-06 26.1 1.3 1.7 2 1 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 OEU12668.1 - 0.022 15.0 1.8 0.045 14.0 2.0 1.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RanBP PF00641.18 OEU12668.1 - 0.077 12.3 1.2 0.077 12.3 1.2 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF4428 PF14471.6 OEU12668.1 - 0.53 10.2 0.2 0.53 10.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.12 OEU12668.1 - 2.1 8.7 8.6 1.4 9.2 3.7 2.4 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase ABC_membrane PF00664.23 OEU12669.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.8 3 1 1 4 4 4 0 ABC transporter transmembrane region C2 PF00168.30 OEU12672.1 - 4.6e-18 65.4 0.0 1.3e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF4497 PF14924.6 OEU12672.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Cwf_Cwc_15 PF04889.12 OEU12672.1 - 0.23 11.2 22.4 0.63 9.7 13.7 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein MAM33 PF02330.16 OEU12673.1 - 1.7e-29 103.3 5.8 2.2e-29 103.0 5.8 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF5338 PF17273.2 OEU12674.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Hydrolase_6 PF13344.6 OEU12675.1 - 2.3e-22 79.0 0.0 5.6e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AMA-1 PF02430.15 OEU12675.1 - 0.0016 17.5 0.2 0.0019 17.2 0.2 1.2 1 0 0 1 1 1 1 Apical membrane antigen 1 DUF1433 PF07252.11 OEU12675.1 - 0.0046 17.2 0.1 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1433) Hydrolase PF00702.26 OEU12675.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Gp_dh_C PF02800.20 OEU12676.1 - 1.8e-66 222.6 0.0 2.7e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU12676.1 - 8e-29 100.0 0.0 1.6e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MaoC_dehydratas PF01575.19 OEU12677.1 - 1e-09 38.0 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain Opi1 PF08618.10 OEU12678.1 - 4.8 6.3 11.3 1.7 7.8 7.5 1.9 2 0 0 2 2 2 0 Transcription factor Opi1 SRP54 PF00448.22 OEU12680.1 - 2.1e-66 223.3 0.0 2.6e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OEU12680.1 - 2.5e-05 24.1 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU12680.1 - 5.9e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRP54_N PF02881.19 OEU12680.1 - 0.00014 22.0 0.6 0.00036 20.7 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_31 PF13614.6 OEU12680.1 - 0.0011 18.9 0.3 0.094 12.6 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 OEU12680.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OEU12680.1 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OEU12680.1 - 0.0032 17.2 0.2 0.0052 16.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU12680.1 - 0.0061 16.9 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU12680.1 - 0.008 16.1 0.7 0.072 13.0 0.7 2.2 1 1 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 OEU12680.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 OEU12680.1 - 0.021 13.8 0.4 0.051 12.5 0.4 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 OEU12680.1 - 0.022 15.2 0.3 0.041 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OEU12680.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 OEU12680.1 - 0.03 14.4 0.2 0.15 12.1 0.2 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Helicase_RecD PF05127.14 OEU12680.1 - 0.044 13.7 0.2 0.11 12.4 0.2 1.7 1 1 1 2 2 2 0 Helicase Fer4_NifH PF00142.18 OEU12680.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_28 PF13521.6 OEU12680.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 OEU12680.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase TrwB_AAD_bind PF10412.9 OEU12680.1 - 0.081 11.8 0.4 0.15 10.9 0.4 1.6 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 OEU12680.1 - 0.084 12.8 0.2 0.2 11.5 0.2 1.7 1 1 0 1 1 1 0 NTPase AAA_7 PF12775.7 OEU12680.1 - 0.093 12.2 0.1 7.7 6.0 0.2 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OEU12680.1 - 0.094 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 OEU12680.1 - 0.094 13.1 0.1 0.19 12.1 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OEU12680.1 - 0.13 12.6 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 OEU12680.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU12680.1 - 0.17 12.1 0.2 0.3 11.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain Sulfotransfer_2 PF03567.14 OEU12681.1 - 9.7e-14 51.9 0.0 1.9e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family AAA_23 PF13476.6 OEU12682.1 - 6.2e-23 82.3 0.0 6.8e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 OEU12682.1 - 9.6e-05 21.9 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain P35 PF02331.15 OEU12682.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein AAA_15 PF13175.6 OEU12682.1 - 0.042 13.5 0.1 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain XendoU PF09412.10 OEU12683.1 - 1.1e-74 251.0 0.1 1.2e-74 250.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 OEU12683.1 - 0.0023 18.3 0.1 0.0065 16.8 0.0 1.7 2 0 0 2 2 2 1 Bacterial EndoU nuclease DUF2610 PF11020.8 OEU12683.1 - 0.06 13.2 0.0 2.2 8.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2610) DUF1350 PF07082.11 OEU12684.1 - 1.7e-18 66.9 0.2 2.8e-16 59.6 0.2 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1350) DER1 PF04511.15 OEU12685.1 - 8.5e-28 97.6 6.6 1e-27 97.4 6.6 1.1 1 0 0 1 1 1 1 Der1-like family BHD_1 PF10403.9 OEU12686.1 - 2.8e-15 55.9 0.0 6.8e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 OEU12686.1 - 2.3e-14 53.5 0.0 4.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 OEU12686.1 - 4.7e-08 33.9 0.3 4.7e-08 33.9 0.3 3.0 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OEU12686.1 - 0.0035 17.8 0.1 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 OEU12686.1 - 0.0076 15.9 0.0 0.0076 15.9 0.0 4.2 4 1 0 4 4 4 2 Rad4 transglutaminase-like domain Glutaredoxin PF00462.24 OEU12687.1 - 2.1e-19 69.5 0.0 3.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PP-binding PF00550.25 OEU12687.1 - 0.067 13.6 0.1 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Phosphopantetheine attachment site GST_N_3 PF13417.6 OEU12687.1 - 0.093 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HECT_2 PF09814.9 OEU12688.1 - 1.9e-12 46.8 8.2 1.9e-12 46.8 8.2 2.4 2 1 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-MYND PF01753.18 OEU12688.1 - 9.7e-07 28.8 12.7 2.9e-06 27.2 12.7 1.9 1 0 0 1 1 1 1 MYND finger Pex16 PF08610.10 OEU12689.1 - 1.3e-16 60.7 0.2 1.8e-16 60.2 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF2615 PF11027.8 OEU12689.1 - 0.028 14.6 3.5 0.14 12.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Reo_P9 PF06043.11 OEU12689.1 - 0.04 13.3 0.2 0.04 13.3 0.2 1.9 2 0 0 2 2 2 0 Reovirus P9-like family Presenilin PF01080.17 OEU12689.1 - 0.085 11.6 1.4 0.17 10.6 1.4 1.5 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 OEU12689.1 - 0.41 10.2 10.8 0.88 9.1 10.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PigN PF04987.14 OEU12689.1 - 0.5 9.2 4.3 0.94 8.3 0.9 2.5 3 0 0 3 3 3 0 Phosphatidylinositolglycan class N (PIG-N) Ctr PF04145.15 OEU12689.1 - 1.4 9.5 4.1 3.6 8.2 4.1 2.0 1 1 0 1 1 1 0 Ctr copper transporter family PEHE PF15275.6 OEU12689.1 - 5.2 7.7 10.6 4.7 7.8 4.6 3.0 3 0 0 3 3 3 0 PEHE domain Aldo_ket_red PF00248.21 OEU12690.1 - 1.8e-35 122.6 0.0 1.2e-33 116.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase PF00144.24 OEU12691.1 - 9.4e-16 57.9 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Geminin PF07412.12 OEU12695.1 - 0.22 11.2 14.1 1.4 8.6 6.4 2.3 1 1 1 2 2 2 0 Geminin DUF680 PF05079.12 OEU12695.1 - 5 7.9 6.9 35 5.2 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF680) DDE_Tnp_1_7 PF13843.6 OEU12697.1 - 1.2e-10 41.3 0.0 6.6e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Transposase IS4 DIMCO_N PF16844.5 OEU12697.1 - 0.0033 17.7 0.2 0.007 16.7 0.2 1.5 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor, N-terminal zf-B_box PF00643.24 OEU12697.1 - 0.004 17.3 4.2 0.01 15.9 4.2 1.7 1 0 0 1 1 1 1 B-box zinc finger SAP PF02037.27 OEU12697.1 - 0.0049 16.6 0.2 0.03 14.1 0.1 2.4 1 1 1 2 2 2 1 SAP domain PHD_2 PF13831.6 OEU12697.1 - 0.014 15.0 2.0 0.033 13.7 2.0 1.7 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 OEU12697.1 - 0.89 9.9 5.1 2 8.8 5.1 1.6 1 0 0 1 1 1 0 C1 domain zf-met PF12874.7 OEU12697.1 - 1.1 9.8 4.0 2.9 8.4 4.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type IBR PF01485.21 OEU12697.1 - 1.1 9.6 4.8 3.3 8.0 4.8 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Mpv17_PMP22 PF04117.12 OEU12698.1 - 1.2e-12 47.8 0.8 2.6e-12 46.8 0.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3119 PF11317.8 OEU12699.1 - 4.2e-33 114.3 0.0 6.1e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) DUF3800 PF12686.7 OEU12700.1 - 0.04 14.5 0.0 0.045 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) URO-D PF01208.17 OEU12701.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) YlbD_coat PF14071.6 OEU12701.1 - 1.8 8.8 6.9 0.076 13.3 1.0 1.7 2 0 0 2 2 2 0 Putative coat protein Orn_Arg_deC_N PF02784.16 OEU12704.1 - 1.2e-22 80.5 0.0 2.2e-22 79.6 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OEU12704.1 - 1.1e-14 54.4 0.0 3.6e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Thioredoxin PF00085.20 OEU12705.1 - 5.2e-12 45.6 0.0 1.1e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU12705.1 - 0.00075 19.9 0.2 0.0026 18.2 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU12705.1 - 0.0016 18.7 0.1 0.0066 16.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU12705.1 - 0.025 14.3 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 OEU12705.1 - 0.029 14.1 0.0 0.088 12.6 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin MFS_1 PF07690.16 OEU12706.1 - 6.3e-19 68.1 17.7 6.2e-18 64.8 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OEU12706.1 - 0.00035 19.2 8.8 0.0024 16.5 2.8 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein DUF983 PF06170.12 OEU12706.1 - 0.013 15.9 0.8 12 6.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DUF2722 PF10846.8 OEU12707.1 - 1.3 7.9 8.5 2.1 7.2 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 OEU12707.1 - 2 7.7 5.8 2.5 7.4 5.8 1.0 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 OEU12707.1 - 3.4 8.1 11.8 45 4.5 11.7 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Abhydrolase_4 PF08386.10 OEU12708.1 - 0.048 13.8 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein ThiF PF00899.21 OEU12709.1 - 7.4e-52 176.1 0.2 1.2e-50 172.2 0.1 2.0 1 1 1 2 2 2 1 ThiF family Pyr_redox_2 PF07992.14 OEU12709.1 - 0.01 15.1 0.1 0.019 14.2 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gp_dh_N PF00044.24 OEU12709.1 - 0.034 14.5 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MutS_V PF00488.21 OEU12710.1 - 5.3e-44 150.5 0.2 5.8e-44 150.4 0.2 1.0 1 0 0 1 1 1 1 MutS domain V AAA PF00004.29 OEU12710.1 - 0.033 14.6 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OEU12710.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OEU12710.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Glycolytic PF00274.19 OEU12711.1 - 1.7e-09 36.9 0.0 2.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Cyanate_lyase PF02560.14 OEU12711.1 - 0.056 13.3 0.2 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Cyanate lyase C-terminal domain Lar_restr_allev PF14354.6 OEU12712.1 - 0.0086 16.4 0.9 0.024 15.0 0.9 1.8 1 1 0 1 1 1 1 Restriction alleviation protein Lar OSTMP1 PF09777.9 OEU12712.1 - 0.048 13.1 1.3 0.073 12.5 1.3 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-Di19 PF05605.12 OEU12712.1 - 0.068 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS91 PF14319.6 OEU12712.1 - 0.12 12.5 3.5 0.077 13.0 1.0 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain GATA PF00320.27 OEU12712.1 - 6.4 6.5 8.5 0.8 9.4 0.6 2.7 2 1 0 2 2 2 0 GATA zinc finger Pro_isomerase PF00160.21 OEU12713.1 - 1.8e-46 158.3 0.2 3.1e-46 157.5 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 OEU12713.1 - 9.7e-30 102.7 0.1 3.2e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 OEU12713.1 - 2.1e-09 36.7 0.9 0.017 15.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU12713.1 - 1.2e-07 31.2 0.5 0.026 14.4 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OEU12713.1 - 0.0012 18.9 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU12713.1 - 0.0036 17.4 0.3 0.47 10.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU12713.1 - 0.0071 17.0 0.1 0.064 13.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU12713.1 - 0.0093 16.2 0.0 0.092 13.0 0.0 2.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU12713.1 - 0.021 15.4 0.1 11 6.6 0.2 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU12713.1 - 0.047 13.9 0.2 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OEU12713.1 - 0.07 13.8 0.4 32 5.4 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU12713.1 - 0.21 12.5 0.2 0.56 11.2 0.1 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 OEU12714.1 - 1e-59 202.6 0.0 2.7e-59 201.3 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OEU12714.1 - 1.5e-35 123.2 0.3 1.5e-35 123.2 0.3 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OEU12714.1 - 7.3e-30 104.2 0.0 1.7e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU12714.1 - 2.5e-06 27.3 0.1 0.0033 17.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.6 OEU12714.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OEU12714.1 - 0.0092 15.7 0.2 2.4 7.8 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OEU12714.1 - 0.054 13.5 0.1 0.47 10.4 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 OEU12714.1 - 0.06 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DNA_ligase_A_M PF01068.21 OEU12715.1 - 0.028 14.1 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain LPD3 PF18798.1 OEU12715.1 - 0.047 13.9 0.5 0.066 13.5 0.5 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 Abhydrolase_3 PF07859.13 OEU12717.1 - 1.8e-16 60.6 0.0 4.4e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OEU12717.1 - 0.00015 20.7 0.0 0.1 11.4 0.0 2.6 3 0 0 3 3 3 2 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OEU12717.1 - 0.083 12.1 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ApbA PF02558.16 OEU12717.1 - 1.4 8.5 3.9 31 4.2 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PAS PF00989.25 OEU12719.1 - 1.8e-122 401.6 10.7 1.6e-20 73.2 0.1 7.5 7 0 0 7 7 7 6 PAS fold PAS_4 PF08448.10 OEU12719.1 - 1.5e-60 202.3 0.0 7.7e-11 42.2 0.0 6.6 6 0 0 6 6 6 6 PAS fold PAS_9 PF13426.7 OEU12719.1 - 5.3e-55 184.1 26.2 4.9e-09 36.4 0.1 7.7 8 0 0 8 8 8 6 PAS domain PAS_3 PF08447.12 OEU12719.1 - 2.7e-46 155.8 0.0 2.5e-06 27.7 0.0 6.6 6 0 0 6 6 6 6 PAS fold PAS_8 PF13188.7 OEU12719.1 - 3.5e-30 103.5 0.4 0.0022 18.0 0.0 6.6 6 0 0 6 6 6 6 PAS domain HATPase_c PF02518.26 OEU12719.1 - 4.3e-21 75.5 0.1 1.5e-20 73.8 0.0 2.0 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 OEU12719.1 - 6e-18 65.4 11.5 0.002 18.7 0.3 6.8 6 0 0 6 6 6 4 PAS domain Response_reg PF00072.24 OEU12719.1 - 5.9e-08 32.9 0.1 1.7e-07 31.4 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OEU12719.1 - 4.1e-07 29.9 0.5 2.4e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Cyclin_C PF02984.19 OEU12719.1 - 0.0033 17.5 0.0 1.2e+02 2.8 0.0 5.5 6 0 0 6 6 6 0 Cyclin, C-terminal domain CobS_N PF12556.8 OEU12719.1 - 0.029 14.1 15.7 3.3 7.5 0.1 5.0 7 0 0 7 7 7 0 Cobaltochelatase CobS subunit N terminal DUF2670 PF10875.8 OEU12719.1 - 0.058 13.5 0.0 1.1e+02 2.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2670) NAD_binding_10 PF13460.6 OEU12721.1 - 4.2e-17 62.6 0.0 8.2e-17 61.7 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OEU12721.1 - 4.2e-05 22.7 0.0 6.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OEU12721.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OEU12721.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 OEU12721.1 - 0.017 15.2 0.1 0.056 13.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OEU12721.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Lactamase_B_3 PF13483.6 OEU12722.1 - 4.4e-24 85.2 0.0 4.5e-23 81.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OEU12722.1 - 0.06 12.9 0.0 0.097 12.2 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Polysacc_deac_1 PF01522.21 OEU12724.1 - 6.9e-09 35.7 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase NMT1 PF09084.11 OEU12725.1 - 4.8e-38 131.3 0.0 6.2e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 OEU12725.1 - 7.4e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 OEU12725.1 - 0.00025 20.8 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family zf-RING_2 PF13639.6 OEU12726.1 - 2.9e-11 43.5 7.3 5.1e-11 42.7 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU12726.1 - 3.9e-11 42.5 2.2 7.4e-11 41.6 2.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU12726.1 - 8.1e-09 35.2 6.8 1.4e-08 34.4 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU12726.1 - 2.8e-07 30.3 4.9 5.5e-07 29.3 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU12726.1 - 3.1e-06 27.4 8.3 8.7e-06 25.9 8.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OEU12726.1 - 0.00055 19.9 4.9 0.00097 19.1 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OEU12726.1 - 0.00062 19.8 3.4 0.0012 18.8 3.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OEU12726.1 - 0.0018 18.3 8.2 0.004 17.1 8.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger LBR_tudor PF09465.10 OEU12726.1 - 0.0019 18.0 2.3 0.0046 16.7 2.3 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain zf-C3HC4_3 PF13920.6 OEU12726.1 - 0.042 13.7 6.4 0.066 13.1 6.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OEU12726.1 - 0.06 13.5 1.2 0.13 12.4 1.2 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Dimer_Tnp_hAT PF05699.14 OEU12726.1 - 0.17 11.7 0.5 0.62 9.9 0.2 2.1 2 0 0 2 2 1 0 hAT family C-terminal dimerisation region Baculo_IE-1 PF05290.11 OEU12726.1 - 0.19 11.7 0.6 0.38 10.7 0.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 OEU12726.1 - 0.22 11.4 4.6 0.44 10.4 4.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU12726.1 - 0.23 11.1 5.7 0.43 10.2 5.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OEU12726.1 - 0.29 11.0 5.7 0.57 10.0 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 OEU12726.1 - 1.9 8.5 6.9 1.1 9.2 4.3 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OEU12726.1 - 8.8 6.6 8.6 14 6.0 7.2 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Methyltransf_25 PF13649.6 OEU12728.1 - 0.0038 17.9 0.0 3.2 8.5 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 OEU12728.1 - 0.0044 16.9 0.0 0.0044 16.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain zf-CCHC PF00098.23 OEU12728.1 - 0.012 15.6 0.5 0.023 14.8 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle VKOR PF07884.14 OEU12729.1 - 2.7e-22 79.2 3.4 2.7e-22 79.2 3.4 3.0 3 1 0 4 4 4 1 Vitamin K epoxide reductase family DUF5336 PF17270.2 OEU12729.1 - 0.091 12.4 0.7 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5336) COX7C PF02935.16 OEU12729.1 - 0.1 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DUF2700 PF10912.8 OEU12729.1 - 0.57 10.2 8.9 2.9 7.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) Hydrolase_like PF13242.6 OEU12730.1 - 3.5e-07 30.2 0.0 7.3e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OEU12730.1 - 5.2e-05 23.4 0.1 0.00014 22.0 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU12730.1 - 0.00012 22.4 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1368 PF07112.11 OEU12731.1 - 0.034 13.0 1.3 0.051 12.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) LRR_4 PF12799.7 OEU12731.1 - 0.28 11.7 13.9 2.7 8.5 1.2 5.5 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) CRAL_TRIO PF00650.20 OEU12732.1 - 1.6e-22 79.9 0.2 3.7e-22 78.7 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU12732.1 - 0.00017 21.8 0.1 0.00058 20.0 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain zf-RING_2 PF13639.6 OEU12733.1 - 4.6e-11 42.9 9.0 8.9e-11 41.9 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU12733.1 - 4.7e-11 42.2 2.5 1e-10 41.2 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU12733.1 - 6.4e-08 32.3 7.8 1.4e-07 31.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU12733.1 - 1.1e-05 25.6 9.4 3.7e-05 23.9 9.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU12733.1 - 6.7e-05 22.7 7.7 6.7e-05 22.7 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU12733.1 - 0.00016 21.6 4.1 0.00016 21.6 4.1 2.2 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU12733.1 - 0.00047 20.0 6.9 0.00097 19.0 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 OEU12733.1 - 0.006 16.5 8.6 0.012 15.6 7.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 OEU12733.1 - 0.045 13.8 6.9 0.13 12.3 6.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OEU12733.1 - 0.16 11.6 7.4 0.3 10.7 7.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU12733.1 - 0.22 11.4 12.4 0.059 13.2 8.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OEU12733.1 - 0.46 10.7 12.1 5.5 7.3 12.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 OEU12733.1 - 0.51 10.3 6.4 1.2 9.1 6.4 1.7 1 0 0 1 1 1 0 PHD-finger HMG_box PF00505.19 OEU12734.1 - 1.2e-15 57.7 7.7 2.1e-13 50.5 7.7 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU12734.1 - 2.5e-14 53.6 6.5 5.4e-14 52.5 6.5 1.5 1 1 0 1 1 1 1 HMG-box domain LAL_C2 PF18603.1 OEU12735.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.9 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 GREB1 PF15782.5 OEU12735.1 - 2.3 5.2 18.0 2.8 5.0 18.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 OEU12735.1 - 4.8 6.0 15.5 5.6 5.8 15.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CRAL_TRIO PF00650.20 OEU12736.1 - 1.5e-11 44.3 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Ank_2 PF12796.7 OEU12737.1 - 1.7e-05 25.3 0.0 0.064 13.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU12737.1 - 0.12 13.0 0.1 3.5 8.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Amidoligase_2 PF12224.8 OEU12738.1 - 2.9e-33 115.6 0.0 4.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme FAM193_C PF15914.5 OEU12738.1 - 0.1 12.4 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 FAM193 family C-terminal F-box-like PF12937.7 OEU12740.1 - 2e-05 24.3 0.0 7.2e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OEU12740.1 - 0.00089 19.1 0.1 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 F-box F-box PF00646.33 OEU12740.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain Amidoligase_2 PF12224.8 OEU12741.1 - 5.7e-36 124.5 0.0 1e-35 123.7 0.0 1.4 1 0 0 1 1 1 1 Putative amidoligase enzyme MIG-14_Wnt-bd PF06664.12 OEU12741.1 - 0.17 11.1 0.2 0.28 10.4 0.2 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion zf-3CxxC_2 PF17180.4 OEU12742.1 - 7.4e-12 45.8 8.7 7.4e-12 45.8 8.7 1.9 2 0 0 2 2 2 1 Zinc-binding domain HARP PF07443.13 OEU12742.1 - 0.00064 19.3 0.0 0.0087 15.7 0.0 2.3 2 0 0 2 2 2 1 HepA-related protein (HARP) zf-CCCH PF00642.24 OEU12742.1 - 0.0013 18.6 3.3 0.0013 18.6 3.3 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU12742.1 - 0.027 14.5 7.4 0.027 14.5 7.4 2.6 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 OEU12742.1 - 0.11 13.2 0.4 0.11 13.2 0.4 2.5 2 0 0 2 2 2 0 Torus domain eIF-5_eIF-2B PF01873.17 OEU12742.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-3CxxC PF13695.6 OEU12742.1 - 0.57 10.7 13.4 20 5.7 12.4 3.4 2 1 0 2 2 2 0 Zinc-binding domain FYVE PF01363.21 OEU12742.1 - 1.4 9.1 11.5 4.6 7.5 11.5 1.9 1 0 0 1 1 1 0 FYVE zinc finger PUB PF09409.10 OEU12743.1 - 7e-17 61.1 0.0 1.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 OEU12743.1 - 3.8e-09 36.2 0.2 1.6e-08 34.2 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 OEU12743.1 - 0.00027 20.8 14.8 0.00027 20.8 14.8 3.6 2 1 1 3 3 3 2 STI1 domain DUF2407 PF10302.9 OEU12743.1 - 0.0014 19.2 0.0 0.0065 17.0 0.0 2.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBCA PF02970.16 OEU12743.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.4 3 0 0 3 3 3 0 Tubulin binding cofactor A GerD PF17898.1 OEU12743.1 - 1.6 8.7 20.5 24 4.9 7.7 2.8 1 1 1 2 2 2 0 Spore germination GerD central core domain TFIIA PF03153.13 OEU12743.1 - 5.6 6.8 28.1 1.8 8.5 24.4 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 OEU12743.1 - 6.1 5.8 6.8 11 5.0 0.0 2.5 2 1 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor NUDIX PF00293.28 OEU12745.1 - 1.1e-08 35.2 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Synuclein PF01387.17 OEU12746.1 - 0.89 9.8 5.4 0.71 10.1 2.9 2.1 2 0 0 2 2 2 0 Synuclein adh_short PF00106.25 OEU12747.1 - 4.5e-29 101.3 0.1 2.9e-24 85.6 0.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU12747.1 - 2e-19 70.1 0.1 1.7e-15 57.3 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU12747.1 - 2.3e-05 24.4 0.1 3.5e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 OEU12747.1 - 0.058 13.4 0.6 0.42 10.6 0.2 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 OEU12747.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Dynactin PF12455.8 OEU12747.1 - 0.14 11.4 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 Dynein associated protein AvrPphF-ORF-2 PF09143.10 OEU12749.1 - 0.022 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 AvrPphF-ORF-2 FANCI_HD1 PF14679.6 OEU12749.1 - 0.061 13.3 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 FANCI helical domain 1 MLVIN_C PF18697.1 OEU12749.1 - 0.13 12.4 1.5 2.4 8.3 0.1 2.1 1 1 1 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain NAD_binding_10 PF13460.6 OEU12750.1 - 1.6e-14 54.2 0.0 3.3e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Secretin_N_2 PF07655.13 OEU12752.1 - 0.0083 16.6 3.0 0.0083 16.6 3.0 3.3 3 0 0 3 3 3 1 Secretin N-terminal domain PRAI PF00697.22 OEU12752.1 - 0.012 15.3 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Proteasome PF00227.26 OEU12752.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit Response_reg PF00072.24 OEU12753.1 - 3e-17 62.8 0.3 3.9e-16 59.2 0.3 2.3 1 1 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 OEU12753.1 - 0.00013 21.4 0.2 0.00033 20.1 0.2 1.7 1 1 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF3388 PF11868.8 OEU12753.1 - 0.0044 16.4 1.4 0.006 15.9 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3388) RXT2_N PF08595.11 OEU12753.1 - 0.053 13.5 0.4 0.053 13.5 0.4 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal Synaptobrevin PF00957.21 OEU12753.1 - 0.063 13.1 1.2 0.15 11.9 1.2 1.6 1 0 0 1 1 1 0 Synaptobrevin DUF3349 PF11829.8 OEU12753.1 - 0.37 11.6 3.7 6.2 7.7 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Imm6 PF14434.6 OEU12754.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 Popeye PF04831.13 OEU12756.1 - 9.7e-12 45.2 0.5 1.2e-11 44.9 0.5 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 OEU12756.1 - 1.6e-07 31.3 0.1 3e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain SspB PF04386.13 OEU12756.1 - 0.0095 15.8 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 Stringent starvation protein B Cupin_2 PF07883.11 OEU12756.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Cupin domain Costars PF14705.6 OEU12757.1 - 1.7e-20 73.0 0.2 1.8e-20 72.9 0.2 1.0 1 0 0 1 1 1 1 Costars SRR PF07709.11 OEU12757.1 - 0.14 12.7 0.7 0.29 11.7 0.7 1.6 1 0 0 1 1 1 0 Seven Residue Repeat Ank_2 PF12796.7 OEU12758.1 - 2.9e-05 24.6 0.0 0.33 11.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU12758.1 - 6.5e-05 23.4 0.1 0.18 12.4 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 OEU12759.1 - 4.1e-14 52.8 0.0 6.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU12759.1 - 2.2e-07 30.9 0.1 3.2e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU12759.1 - 4.9e-06 26.9 0.0 8.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU12759.1 - 5.4e-06 26.3 0.0 8.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OEU12759.1 - 0.0012 19.0 0.2 0.0021 18.1 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 OEU12759.1 - 0.0045 16.7 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 OEU12759.1 - 0.024 14.1 2.8 0.025 14.0 1.5 1.6 1 1 1 2 2 2 0 Putative acetyl-transferase V1R PF03402.14 OEU12759.1 - 0.039 13.6 0.1 0.047 13.3 0.1 1.1 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R Coilin_N PF15862.5 OEU12760.1 - 0.00052 19.8 0.0 0.0022 17.8 0.0 2.0 1 1 0 1 1 1 1 Coilin N-terminus PGA2 PF07543.12 OEU12760.1 - 3.6 7.6 16.6 0.48 10.4 10.2 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Rhomboid PF01694.22 OEU12761.1 - 1.1e-30 106.7 13.5 1.1e-30 106.7 13.5 1.8 2 0 0 2 2 2 1 Rhomboid family Spot_14 PF07084.12 OEU12761.1 - 0.23 11.6 0.0 0.37 10.9 0.0 1.2 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Ank_2 PF12796.7 OEU12762.1 - 0.0039 17.7 0.0 0.029 14.9 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU12762.1 - 0.026 15.0 0.9 20 6.1 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 OEU12762.1 - 0.1 13.2 0.1 16 6.2 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SAM_Ste50p PF09235.10 OEU12762.1 - 0.13 12.5 0.4 3.3 8.0 0.1 2.9 2 1 1 3 3 3 0 Ste50p, sterile alpha motif ThiF PF00899.21 OEU12764.1 - 7.5e-42 143.4 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 OEU12764.1 - 0.0034 17.1 0.0 0.0092 15.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus 2-Hacid_dh_C PF02826.19 OEU12764.1 - 0.05 13.0 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OEU12764.1 - 0.19 11.8 0.0 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase LON_substr_bdg PF02190.16 OEU12765.1 - 1.5e-06 28.3 5.6 2e-06 27.9 5.6 1.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF1877 PF08974.10 OEU12765.1 - 0.014 15.5 0.6 0.029 14.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) RRN3 PF05327.11 OEU12765.1 - 0.062 11.8 3.4 0.075 11.6 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 OEU12765.1 - 0.2 9.7 4.7 0.25 9.4 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_3 PF13606.6 OEU12766.1 - 0.012 16.1 0.1 80 4.3 0.0 4.6 4 0 0 4 4 4 0 Ankyrin repeat TTR-52 PF01060.23 OEU12766.1 - 0.094 13.4 0.1 39 5.0 0.0 2.8 3 0 0 3 3 3 0 Transthyretin-like family AAA_12 PF13087.6 OEU12767.1 - 9.8e-32 110.2 0.3 1.1e-31 110.1 0.3 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OEU12767.1 - 1.2e-05 25.1 0.1 2.5e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OEU12767.1 - 7.8e-05 22.5 0.0 8.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 OEU12767.1 - 0.0029 17.0 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PPP4R2 PF09184.11 OEU12768.1 - 2.3 7.7 16.3 3.3 7.2 16.3 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4604 PF15377.6 OEU12768.1 - 3.1 8.2 23.9 1.7 9.0 14.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 OEU12768.1 - 3.2 7.5 14.9 5 6.9 14.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 OEU12768.1 - 5.1 7.0 11.9 6.2 6.7 11.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TUSC2 PF15000.6 OEU12768.1 - 5.1 7.4 11.5 0.17 12.2 2.9 2.1 1 1 0 2 2 2 0 Tumour suppressor candidate 2 CCSAP PF15748.5 OEU12768.1 - 9.9 6.2 20.7 12 6.0 20.7 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CHRD PF07452.12 OEU12769.1 - 0.00016 22.7 0.2 0.0012 19.7 0.2 2.2 1 1 0 1 1 1 1 CHRD domain SKI PF01202.22 OEU12770.1 - 1.6e-43 148.5 0.0 1.8e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OEU12770.1 - 5.6e-06 26.9 0.0 2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OEU12770.1 - 8.7e-05 23.0 0.1 0.0017 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU12770.1 - 0.00025 21.2 0.0 0.00075 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 OEU12770.1 - 0.0014 18.8 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA PF00004.29 OEU12770.1 - 0.022 15.2 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU12770.1 - 0.031 14.7 0.1 0.034 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain dNK PF01712.19 OEU12770.1 - 0.054 13.3 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 OEU12770.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.6 1 1 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 OEU12770.1 - 0.14 11.9 0.2 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU12770.1 - 0.17 12.2 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DivIVA PF05103.13 OEU12771.1 - 0.009 16.1 1.8 0.067 13.3 1.8 2.0 1 1 0 1 1 1 1 DivIVA protein ORC5_C PF14630.6 OEU12772.1 - 8.9e-28 97.6 0.0 8.9e-28 97.6 0.0 4.9 3 1 2 5 5 5 1 Origin recognition complex (ORC) subunit 5 C-terminus Otopetrin PF03189.13 OEU12772.1 - 2.1 7.1 17.8 5 5.8 17.8 1.6 1 0 0 1 1 1 0 Otopetrin Peptidase_S9 PF00326.21 OEU12773.1 - 3e-47 160.8 0.0 5.6e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OEU12773.1 - 5.2e-10 39.2 0.0 9.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OEU12773.1 - 8.9e-05 21.9 0.2 0.00071 18.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OEU12773.1 - 0.0071 16.0 0.1 0.063 12.9 0.0 2.4 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OEU12773.1 - 0.02 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.12 OEU12773.1 - 0.054 13.5 4.5 7.7 6.6 0.4 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Abhydrolase_4 PF08386.10 OEU12773.1 - 0.072 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein UPF0020 PF01170.18 OEU12774.1 - 1.3e-13 51.1 0.4 6.4e-12 45.6 0.0 3.1 3 1 0 3 3 3 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OEU12774.1 - 1.3e-07 31.6 0.2 0.0036 17.0 0.0 2.9 2 1 0 2 2 2 2 DNA methylase MethyltransfD12 PF02086.15 OEU12774.1 - 0.072 12.8 5.6 0.18 11.4 0.0 3.3 4 0 0 4 4 4 0 D12 class N6 adenine-specific DNA methyltransferase ETRAMP PF09716.10 OEU12774.1 - 5.5 7.1 6.3 6.1 7.0 1.8 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PI3_PI4_kinase PF00454.27 OEU12775.1 - 3e-45 155.0 0.0 2.2e-42 145.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAS_N PF17828.1 OEU12776.1 - 0.031 14.3 0.0 0.032 14.2 0.0 1.0 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta LRR_12 PF18837.1 OEU12776.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat NADH_dehy_S2_C PF06444.11 OEU12777.1 - 0.07 13.7 0.1 0.19 12.3 0.1 1.8 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus EamA PF00892.20 OEU12778.1 - 1.7e-19 70.3 22.8 6.5e-13 49.0 10.0 3.1 2 1 1 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 OEU12778.1 - 0.0031 16.7 0.0 0.015 14.5 0.0 2.1 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF3185 PF11381.8 OEU12778.1 - 0.13 12.3 4.2 3.3 7.8 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) CYSTM PF12734.7 OEU12778.1 - 0.28 11.5 0.8 0.56 10.6 0.8 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Myb_DNA-binding PF00249.31 OEU12780.1 - 2.9e-07 30.5 0.9 4.8e-07 29.9 0.9 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4611 PF15387.6 OEU12780.1 - 0.0029 17.8 4.3 0.012 15.8 4.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) DUF5014 PF16406.5 OEU12780.1 - 0.022 15.0 0.1 0.072 13.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5014) NIR_SIR PF01077.22 OEU12781.1 - 6.2e-48 162.3 0.0 1.1e-41 142.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OEU12781.1 - 2.4e-21 75.4 0.0 4.6e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Vps55 PF04133.14 OEU12782.1 - 0.19 11.7 0.0 0.54 10.2 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 55 CDC45 PF02724.14 OEU12783.1 - 2.2 6.5 9.3 2.3 6.4 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 OEU12784.1 - 1.4e-09 38.4 2.0 0.0002 22.0 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU12784.1 - 2.7e-08 34.0 0.0 0.00015 22.0 0.0 4.1 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU12784.1 - 0.0033 16.4 0.1 0.082 11.8 0.0 2.9 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OEU12784.1 - 0.14 12.1 0.8 24 5.0 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 OEU12784.1 - 5.3 6.8 5.9 2.4 7.9 0.1 3.4 4 1 1 5 5 5 0 Proteasome subunit A N-terminal signature Voltage_CLC PF00654.20 OEU12785.1 - 9.5e-55 186.3 28.0 1.2e-54 186.0 28.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 OEU12785.1 - 1.9e-13 50.6 0.3 1.8e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain Neurensin PF14927.6 OEU12785.1 - 2.3 7.9 4.7 7.2 6.3 0.2 2.7 2 0 0 2 2 2 0 Neurensin LRR_4 PF12799.7 OEU12786.1 - 0.85 10.1 9.8 0.58 10.7 1.8 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) COesterase PF00135.28 OEU12787.1 - 7.6e-78 262.6 0.0 1.2e-77 262.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OEU12787.1 - 0.0006 19.7 0.0 0.0022 17.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold SASA PF03629.18 OEU12788.1 - 9.5e-23 81.0 0.3 1.1e-17 64.5 0.0 3.4 1 1 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase tRNA_synt_1c_R1 PF04558.15 OEU12788.1 - 0.026 14.5 3.5 0.065 13.2 3.5 1.6 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Ost5 PF05251.12 OEU12789.1 - 0.063 13.5 0.1 0.063 13.5 0.1 3.0 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF3671 PF12420.8 OEU12789.1 - 2.7 8.1 17.9 0.058 13.5 5.7 3.4 2 1 2 4 4 4 0 Protein of unknown function Gly_transf_sug PF04488.15 OEU12790.1 - 1.1e-06 29.2 0.3 3.6e-06 27.5 0.3 2.0 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Meis_PKNOX_N PF16493.5 OEU12790.1 - 0.051 13.9 0.2 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 AI-2E_transport PF01594.16 OEU12791.1 - 0.062 12.4 0.1 0.062 12.4 0.1 1.9 2 0 0 2 2 2 0 AI-2E family transporter Peptidase_S49_N PF08496.10 OEU12791.1 - 3.3 7.8 7.3 28 4.7 3.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Conotoxin PF02950.17 OEU12791.1 - 7.3 7.7 11.6 0.27 12.3 0.4 3.7 2 2 0 2 2 2 0 Conotoxin Sulfotransfer_2 PF03567.14 OEU12793.1 - 1.3e-06 28.5 12.7 1.3e-06 28.5 12.7 2.9 2 2 0 2 2 2 1 Sulfotransferase family adh_short PF00106.25 OEU12794.1 - 7.1e-11 41.9 5.0 7.5e-07 28.8 2.3 4.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OEU12794.1 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OEU12794.1 - 0.016 14.8 0.8 0.79 9.2 0.0 3.0 3 0 0 3 3 3 0 Enoyl-(Acyl carrier protein) reductase MARVEL PF01284.23 OEU12794.1 - 0.047 13.7 4.3 0.076 13.0 1.8 2.4 2 1 1 3 3 3 0 Membrane-associating domain Trypsin PF00089.26 OEU12795.1 - 4.6e-27 95.3 0.0 8.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU12795.1 - 0.0054 17.6 0.0 0.008 17.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain ShK PF01549.24 OEU12795.1 - 1.3 9.6 20.2 0.61 10.7 4.5 3.4 3 0 0 3 3 3 0 ShK domain-like PRiA4_ORF3 PF07929.11 OEU12796.1 - 7.8e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 OEU12796.1 - 2.5e-09 37.1 10.6 4.3e-09 36.3 10.6 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU12796.1 - 6.7 6.9 7.6 49 4.1 7.6 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 LAGLIDADG_WhiA PF14527.6 OEU12797.1 - 0.0096 16.0 0.1 0.04 14.0 0.0 2.1 2 0 0 2 2 2 1 WhiA LAGLIDADG-like domain F-box-like PF12937.7 OEU12797.1 - 0.022 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like Tubulin_3 PF14881.6 OEU12797.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain CAMSAP_CH PF11971.8 OEU12797.1 - 0.059 13.2 0.5 0.19 11.6 0.5 1.8 1 0 0 1 1 1 0 CAMSAP CH domain MFS_1 PF07690.16 OEU12798.1 - 3.5e-14 52.5 32.7 2.5e-13 49.7 30.6 2.9 2 1 2 4 4 4 1 Major Facilitator Superfamily DUF755 PF05501.11 OEU12798.1 - 5.7 7.2 22.2 0.42 10.9 6.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF755) SPOR PF05036.13 OEU12799.1 - 0.18 12.2 0.2 14 6.1 0.1 3.1 3 0 0 3 3 3 0 Sporulation related domain Sulfotransfer_4 PF17784.1 OEU12800.1 - 0.0044 16.9 1.2 0.044 13.6 0.1 3.3 3 2 0 3 3 3 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU12800.1 - 0.24 11.7 4.3 0.23 11.8 0.1 2.9 2 1 0 2 2 2 0 Sulfotransferase family TFIIA PF03153.13 OEU12800.1 - 1.1 9.2 29.2 2.3 8.1 19.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HA PF03457.14 OEU12801.1 - 8.3 6.8 8.2 0.19 12.1 0.7 2.1 2 0 0 2 2 2 0 Helicase associated domain Fasciclin PF02469.22 OEU12802.1 - 6.7e-09 36.0 1.6 7.9e-08 32.6 0.5 2.2 2 0 0 2 2 2 1 Fasciclin domain zf-MYND PF01753.18 OEU12803.1 - 5.8e-06 26.3 7.5 1.2e-05 25.3 7.5 1.5 1 0 0 1 1 1 1 MYND finger DUF3449 PF11931.8 OEU12803.1 - 0.013 15.3 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) HTH_Tnp_Tc5 PF03221.16 OEU12804.1 - 0.039 14.0 0.1 0.082 12.9 0.1 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Dishevelled PF02377.15 OEU12804.1 - 2 8.8 6.6 0.37 11.2 2.3 2.0 1 1 1 2 2 2 0 Dishevelled specific domain DUF3824 PF12868.7 OEU12806.1 - 0.03 15.0 1.9 0.03 15.0 1.9 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SOBP PF15279.6 OEU12806.1 - 1.7 9.2 9.2 2.1 8.9 9.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein AIM3 PF17096.5 OEU12806.1 - 1.7 9.6 10.5 0.85 10.6 2.2 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF3391 PF11871.8 OEU12806.1 - 1.8 9.1 9.3 1.4 9.5 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) GREB1 PF15782.5 OEU12806.1 - 3 4.9 12.1 3.2 4.8 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 OEU12806.1 - 3.1 6.0 12.8 3.4 5.8 12.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Hydin_ADK PF17213.3 OEU12806.1 - 3.5 7.9 10.4 4.6 7.5 10.4 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain LRR_1 PF00560.33 OEU12807.1 - 0.12 13.0 2.0 35 5.5 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat Bestrophin PF01062.21 OEU12808.1 - 3.6e-26 92.2 0.0 1.7e-23 83.4 0.0 2.2 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3698 PF12479.8 OEU12808.1 - 0.13 12.8 2.7 0.16 12.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3698) PGA2 PF07543.12 OEU12808.1 - 1.8 8.5 11.2 0.24 11.4 0.7 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF778 PF05608.12 OEU12809.1 - 4.9e-10 40.1 0.0 0.00034 21.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF778) MRP-S32 PF10210.9 OEU12809.1 - 0.0012 19.3 2.2 1 9.9 0.2 2.7 2 1 0 2 2 2 2 Mitochondrial 28S ribosomal protein S32 TPR_18 PF13512.6 OEU12809.1 - 0.91 9.6 4.5 0.41 10.8 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GDPD PF03009.17 OEU12810.1 - 4e-05 23.5 0.0 0.088 12.5 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family ChaB PF06150.12 OEU12811.1 - 0.0046 17.5 4.8 0.97 10.1 0.3 3.6 3 0 0 3 3 3 3 ChaB Methyltransf_16 PF10294.9 OEU12813.1 - 3.9e-20 72.3 1.7 4.7e-16 59.0 0.2 2.5 2 0 0 2 2 2 2 Lysine methyltransferase FRQ PF09421.10 OEU12813.1 - 0.0033 15.5 4.6 0.0033 15.5 4.6 2.1 2 0 0 2 2 2 1 Frequency clock protein MTS PF05175.14 OEU12813.1 - 0.016 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 OEU12813.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OEU12813.1 - 0.15 12.8 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain BUD22 PF09073.10 OEU12813.1 - 0.33 10.2 12.0 0.02 14.2 6.8 1.5 2 0 0 2 2 2 0 BUD22 AATF-Che1 PF13339.6 OEU12813.1 - 0.8 10.4 5.1 1.9 9.2 2.6 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Sporozoite_P67 PF05642.11 OEU12813.1 - 1.8 6.6 15.7 0.47 8.5 1.5 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NAD_binding_8 PF13450.6 OEU12815.1 - 4.6e-07 30.0 0.7 1.4e-06 28.4 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU12815.1 - 7.4e-07 29.1 5.1 9.8e-07 28.7 1.1 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OEU12815.1 - 1.2e-05 24.9 0.0 2.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU12815.1 - 0.00021 20.6 4.0 0.0032 16.7 1.6 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU12815.1 - 0.00063 19.1 0.3 0.0022 17.3 0.3 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OEU12815.1 - 0.0028 18.2 0.3 0.04 14.5 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OEU12815.1 - 0.0045 16.9 0.5 0.012 15.5 0.5 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OEU12815.1 - 0.012 14.7 0.9 0.024 13.7 0.9 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OEU12815.1 - 0.033 13.4 0.3 0.065 12.5 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.15 OEU12815.1 - 0.086 13.0 0.1 0.56 10.4 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.6 OEU12815.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GRP PF07172.11 OEU12818.1 - 2.5 8.8 8.1 18 6.1 2.0 3.1 2 0 0 2 2 2 0 Glycine rich protein family DUF572 PF04502.13 OEU12821.1 - 0.00072 19.3 13.2 0.00072 19.3 13.2 4.3 3 1 0 4 4 4 2 Family of unknown function (DUF572) PT PF04886.12 OEU12822.1 - 4.3e-08 32.6 84.0 0.0003 20.2 10.2 6.2 2 2 3 5 5 5 4 PT repeat PT PF04886.12 OEU12823.1 - 9.8e-10 37.8 57.2 0.022 14.3 10.9 5.2 1 1 2 3 3 3 2 PT repeat PT PF04886.12 OEU12824.1 - 2.6e-26 90.9 150.8 0.00015 21.2 10.3 11.5 1 1 7 8 8 8 7 PT repeat PT PF04886.12 OEU12826.1 - 8.1e-05 22.1 13.2 8.1e-05 22.1 13.2 1.8 2 0 0 2 2 2 1 PT repeat LCAT PF02450.15 OEU12827.1 - 1.6e-36 126.3 1.3 1.2e-34 120.2 0.0 3.0 3 1 0 3 3 3 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 OEU12827.1 - 0.081 12.6 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein K_channel_TID PF07941.11 OEU12832.1 - 0.029 14.8 0.4 0.029 14.8 0.4 3.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain PKcGMP_CC PF16808.5 OEU12832.1 - 0.86 9.5 6.4 0.27 11.1 0.4 2.7 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ArfGap PF01412.18 OEU12833.1 - 1.3e-26 93.0 0.7 2.8e-26 91.9 0.7 1.7 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf C_Hendra PF16821.5 OEU12833.1 - 0.058 13.3 0.6 0.096 12.6 0.6 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses TF_Zn_Ribbon PF08271.12 OEU12833.1 - 0.075 12.6 1.1 0.32 10.6 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3973 PF13119.6 OEU12833.1 - 0.32 11.1 2.5 2.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) BTB_2 PF02214.22 OEU12834.1 - 1.8e-06 28.2 0.3 9.8e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain DUF2681 PF10883.8 OEU12834.1 - 0.038 14.4 0.5 0.069 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) BTB_3 PF16017.5 OEU12834.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.8 2 1 0 2 2 2 0 BTB/POZ domain CheR PF01739.18 OEU12835.1 - 0.0044 16.5 0.0 0.83 9.1 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 OEU12835.1 - 0.03 15.0 0.0 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L9_N PF01281.19 OEU12836.1 - 1.1e-08 34.5 0.1 2e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DOT1 PF08123.13 OEU12836.1 - 0.04 13.5 0.2 0.082 12.4 0.2 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 Myc_N PF01056.18 OEU12837.1 - 2.1 8.2 15.5 0.027 14.4 6.4 2.4 3 0 0 3 3 3 0 Myc amino-terminal region FAM176 PF14851.6 OEU12837.1 - 3.3 7.4 17.2 1.9 8.1 5.8 3.9 4 0 0 4 4 4 0 FAM176 family zf-C2H2 PF00096.26 OEU12838.1 - 2.8e-06 27.5 0.6 0.012 16.1 0.1 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OEU12838.1 - 9.8e-05 22.9 0.5 1.1 10.3 0.1 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OEU12838.1 - 0.035 14.2 5.2 1.9 8.7 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 OEU12838.1 - 3.3 8.3 5.2 5.8 7.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-LYAR PF08790.11 OEU12838.1 - 5 7.1 8.3 1.9 8.4 0.1 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Mito_carr PF00153.27 OEU12839.1 - 5.5e-36 122.4 2.8 1.2e-13 50.8 0.0 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ETRAMP PF09716.10 OEU12839.1 - 0.27 11.3 4.6 12 6.0 4.6 2.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Rhodanese PF00581.20 OEU12840.1 - 0.00015 22.2 0.0 0.00032 21.2 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain VWA PF00092.28 OEU12841.1 - 9.5e-11 42.3 0.2 3e-10 40.6 0.2 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OEU12841.1 - 1.4e-10 41.7 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OEU12841.1 - 0.00038 19.9 0.0 0.0006 19.3 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein K_channel_TID PF07941.11 OEU12843.1 - 1.2 9.6 8.9 4.5 7.8 1.4 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PAP1 PF08601.10 OEU12843.1 - 3.9 7.1 13.9 4.4 6.9 13.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Colicin PF01024.19 OEU12844.1 - 0.89 9.4 6.0 1.5 8.7 6.0 1.3 1 0 0 1 1 1 0 Colicin pore forming domain DUF4551 PF15087.6 OEU12845.1 - 3.5 6.4 25.6 1.4 7.7 20.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 OEU12847.1 - 5.4e-33 114.5 0.0 6.4e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU12847.1 - 9.5e-27 93.9 0.0 1.1e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU12847.1 - 0.0009 18.6 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RE_TdeIII PF09520.10 OEU12847.1 - 0.077 12.6 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DnaJ PF00226.31 OEU12848.1 - 7e-08 32.5 0.0 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 2 DnaJ domain Phenol_monoox PF04663.12 OEU12848.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Phenol hydroxylase conserved region DUF4576 PF15144.6 OEU12851.1 - 0.051 13.5 1.2 6.1 6.8 0.2 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4576) Kei1 PF08552.11 OEU12851.1 - 8.9 6.1 9.2 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 4HBT PF03061.22 OEU12853.1 - 0.0072 16.7 0.1 0.46 10.9 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily Pyr_redox_2 PF07992.14 OEU12854.1 - 1.8e-43 148.9 0.0 2.1e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU12854.1 - 1.2e-08 35.4 0.0 2.6e-05 24.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU12854.1 - 0.005 17.0 0.0 0.045 14.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF5442 PF17514.2 OEU12854.1 - 0.19 11.9 3.7 0.3 11.3 2.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) SR-25 PF10500.9 OEU12856.1 - 0.0073 15.9 7.6 0.0073 15.9 7.6 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SIN1 PF05422.12 OEU12856.1 - 0.075 13.6 3.6 0.098 13.2 0.2 2.1 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) SOBP PF15279.6 OEU12856.1 - 0.18 12.4 6.0 0.2 12.2 6.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein YqzE PF14038.6 OEU12856.1 - 2.4 8.2 6.4 1.6 8.8 0.4 2.4 2 0 0 2 2 2 0 YqzE-like protein Abhydrolase_1 PF00561.20 OEU12857.1 - 0.00036 20.2 0.0 0.0021 17.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OEU12857.1 - 0.047 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGA2 PF07543.12 OEU12857.1 - 0.32 11.0 4.9 0.6 10.1 0.6 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 Ribosomal_S16 PF00886.19 OEU12859.1 - 7.9e-26 89.9 0.0 1.2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Sif PF06767.11 OEU12860.1 - 0.0091 15.0 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Sif protein CSG2 PF16965.5 OEU12860.1 - 0.83 8.5 3.9 1.3 7.9 3.9 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Biotin_lipoyl PF00364.22 OEU12861.1 - 0.0044 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme DDHD PF02862.17 OEU12861.1 - 0.021 15.0 2.6 0.027 14.6 2.6 1.1 1 0 0 1 1 1 0 DDHD domain Nab6_mRNP_bdg PF10567.9 OEU12861.1 - 0.053 13.0 5.9 0.073 12.6 5.9 1.1 1 0 0 1 1 1 0 RNA-recognition motif Menin PF05053.13 OEU12861.1 - 0.45 8.8 4.9 0.57 8.5 4.9 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 OEU12861.1 - 0.67 8.7 3.1 0.81 8.4 3.1 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OEU12861.1 - 1.8 7.0 7.7 2 6.9 7.7 1.1 1 0 0 1 1 1 0 Macoilin family Carb_anhydrase PF00194.21 OEU12862.1 - 1.1e-12 48.0 6.8 7.8e-07 28.9 0.0 4.5 4 1 0 4 4 4 3 Eukaryotic-type carbonic anhydrase Sulfotransfer_2 PF03567.14 OEU12863.1 - 0.00076 19.5 8.0 0.013 15.4 8.0 2.7 1 1 0 1 1 1 1 Sulfotransferase family ANAPC8 PF04049.13 OEU12863.1 - 0.35 10.9 3.1 0.47 10.5 0.1 2.6 3 0 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 Mucin PF01456.17 OEU12863.1 - 1 9.3 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Lipase_3 PF01764.25 OEU12864.1 - 0.0015 18.4 0.6 0.0086 15.9 0.6 2.0 1 1 0 1 1 1 1 Lipase (class 3) Thyroglobulin_1 PF00086.18 OEU12864.1 - 1 9.1 6.4 4.9 6.9 6.4 1.9 1 1 0 1 1 1 0 Thyroglobulin type-1 repeat Guanylate_cyc PF00211.20 OEU12865.1 - 2e-45 154.7 0.0 4.7e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 OEU12865.1 - 9.9e-29 100.7 0.1 2e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SUIM_assoc PF16619.5 OEU12867.1 - 0.016 15.2 4.8 1.3 9.1 0.3 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3391 PF11871.8 OEU12867.1 - 0.16 12.5 0.3 0.4 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3348 PF11828.8 OEU12867.1 - 2.1 8.0 4.8 4 7.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) PRIMA1 PF16101.5 OEU12868.1 - 1.1 9.3 6.2 4 7.5 6.2 2.1 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Dirigent PF03018.14 OEU12869.1 - 0.079 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Dirigent-like protein MatE PF01554.18 OEU12870.1 - 1.7e-10 40.8 18.7 2.6e-10 40.2 18.7 1.2 1 0 0 1 1 1 1 MatE SP_C-Propep PF08999.10 OEU12870.1 - 0.008 15.9 1.5 0.012 15.3 1.3 1.4 1 1 0 1 1 1 1 Surfactant protein C, N terminal propeptide CCDC71L PF15374.6 OEU12871.1 - 0.094 12.0 9.2 0.012 14.9 4.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L DUF2375 PF09558.10 OEU12871.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Mcp5_PH PF12814.7 OEU12871.1 - 0.22 11.7 3.6 2.3 8.3 0.3 2.7 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Nucleotid_trans PF03407.16 OEU12872.1 - 9.7e-22 78.0 2.2 1.2e-21 77.7 2.2 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Aldo_ket_red PF00248.21 OEU12874.1 - 4e-22 78.8 0.2 1.2e-17 64.1 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family NeuB PF03102.14 OEU12874.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 NeuB family MFS_1 PF07690.16 OEU12875.1 - 5.8e-25 88.0 17.8 5.9e-23 81.4 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU12875.1 - 1.2e-05 24.4 10.4 0.0068 15.3 6.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.8 OEU12875.1 - 0.063 11.9 13.7 0.062 11.9 2.9 2.5 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like OATP PF03137.20 OEU12875.1 - 0.26 9.5 10.4 4.4 5.5 0.5 3.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MASE3 PF17159.4 OEU12875.1 - 7.5 6.1 10.3 0.14 11.8 2.5 2.1 3 0 0 3 3 3 0 Membrane-associated sensor domain NUDIX PF00293.28 OEU12876.1 - 1.3e-15 57.6 0.0 1.6e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 OEU12876.1 - 6.2e-05 22.6 5.3 0.00059 19.4 3.6 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 OEU12876.1 - 0.0057 16.7 4.5 0.0071 16.3 3.5 1.7 2 0 0 2 2 2 1 Double zinc ribbon Nudix_N_2 PF14803.6 OEU12876.1 - 0.039 13.9 3.9 0.13 12.2 0.0 2.8 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 OEU12876.1 - 0.059 13.1 0.3 0.059 13.1 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_11 PF11682.8 OEU12876.1 - 0.094 12.7 0.9 0.15 12.1 0.9 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon zf-LSD1 PF06943.12 OEU12876.1 - 0.16 11.8 6.1 0.27 11.1 6.1 1.4 1 0 0 1 1 1 0 LSD1 zinc finger DUF1451 PF07295.11 OEU12876.1 - 0.18 11.8 2.6 0.28 11.2 2.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain YhfH PF14149.6 OEU12876.1 - 0.41 10.7 6.8 0.34 10.9 4.9 1.8 2 0 0 2 2 2 0 YhfH-like protein A2L_zn_ribbon PF08792.10 OEU12876.1 - 1.2 9.0 7.6 6.3 6.6 7.6 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF35_N PF12172.8 OEU12876.1 - 2.3 8.2 10.2 1.3 9.0 1.9 2.8 3 1 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HSF_DNA-bind PF00447.17 OEU12877.1 - 2.3e-12 47.4 0.0 2.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Mucin PF01456.17 OEU12878.1 - 0.00012 22.0 11.5 0.00012 22.0 11.5 3.0 3 0 0 3 3 3 1 Mucin-like glycoprotein Imm5 PF14423.6 OEU12878.1 - 0.14 12.3 4.7 0.45 10.7 1.0 2.7 2 0 0 2 2 2 0 Immunity protein Imm5 SDA1 PF05285.12 OEU12878.1 - 4.3 6.7 34.0 1.9 7.9 2.0 3.2 3 0 0 3 3 3 0 SDA1 DUF2256 PF10013.9 OEU12880.1 - 4.3e-19 68.3 13.3 4.3e-19 68.3 13.3 2.6 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2256) DUF2685 PF10886.8 OEU12880.1 - 1.6 9.0 5.6 20 5.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) ESM4 PF15952.5 OEU12881.1 - 0.0079 16.6 8.1 0.015 15.7 8.1 1.5 1 0 0 1 1 1 1 Enhancer of split M4 family Dymeclin PF09742.9 OEU12882.1 - 1.9e-172 575.0 0.0 2.1e-172 574.8 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 OEU12882.1 - 1.3e-160 536.3 0.6 2e-132 443.0 0.2 3.3 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Pkinase PF00069.25 OEU12883.1 - 1.1e-11 44.6 0.1 2.4e-10 40.2 0.1 2.5 1 1 0 1 1 1 1 Protein kinase domain NOA36 PF06524.12 OEU12883.1 - 8.4 5.6 26.6 3.4 6.9 12.9 2.3 2 0 0 2 2 2 0 NOA36 protein Acyl_transf_3 PF01757.22 OEU12884.1 - 5.7e-23 81.5 40.7 5.7e-23 81.5 40.7 2.1 2 0 0 2 2 2 1 Acyltransferase family F-box-like PF12937.7 OEU12886.1 - 6.6e-10 38.7 0.1 0.00097 19.0 0.0 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 OEU12886.1 - 1e-08 34.9 0.1 0.00035 20.4 0.0 2.7 2 0 0 2 2 2 2 F-box domain F-box_4 PF15966.5 OEU12886.1 - 6.5e-06 26.0 0.3 0.033 14.1 0.1 2.5 1 1 1 2 2 2 2 F-box LRR_8 PF13855.6 OEU12886.1 - 3.4e-05 23.5 1.6 0.00021 21.0 0.2 3.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 OEU12886.1 - 5.3e-05 23.5 4.2 0.0045 17.4 0.1 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OEU12886.1 - 0.037 14.0 6.4 0.034 14.1 1.2 2.6 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) PDT PF00800.18 OEU12887.1 - 1.4e-47 161.9 0.0 2.9e-47 160.9 0.0 1.5 2 0 0 2 2 2 1 Prephenate dehydratase RAP1 PF07218.11 OEU12889.1 - 0.091 11.0 5.7 0.12 10.6 5.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TRP PF06011.12 OEU12889.1 - 0.18 10.5 1.0 0.28 9.9 1.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Macoilin PF09726.9 OEU12889.1 - 4.2 5.8 7.9 6.3 5.2 7.9 1.3 1 0 0 1 1 1 0 Macoilin family DnaJ PF00226.31 OEU12890.1 - 1.5e-22 79.5 0.8 1.6e-22 79.4 0.8 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OEU12890.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 A repeated domain in UCH-protein FAD_binding_8 PF08022.12 OEU12891.1 - 3.1e-17 62.6 0.0 6.7e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OEU12891.1 - 1.7e-09 38.0 3.1 4.2e-05 23.7 0.1 2.5 2 1 0 2 2 2 2 Ferric reductase NAD binding domain GxGYxYP_C PF14323.6 OEU12891.1 - 0.019 14.9 0.2 0.038 13.9 0.2 1.5 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Phage_head_chap PF11113.8 OEU12891.1 - 0.05 13.7 0.4 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Head assembly gene product K_channel_TID PF07941.11 OEU12893.1 - 0.43 11.1 5.1 1.2 9.6 5.1 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain MscS_TM PF12794.7 OEU12893.1 - 4.4 6.1 6.4 0.83 8.4 1.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 NAD_binding_1 PF00175.21 OEU12895.1 - 7.9e-13 49.0 0.0 1.5e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU12895.1 - 5.1e-12 46.0 0.0 6e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Putative_PNPOx PF01243.20 OEU12895.1 - 0.0002 21.5 0.1 0.0021 18.2 0.0 2.5 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 OEU12895.1 - 0.00056 20.1 0.0 0.0019 18.4 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ESSS PF10183.9 OEU12897.1 - 0.18 12.0 1.1 6 7.1 0.0 3.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NAD_binding_10 PF13460.6 OEU12898.1 - 6e-09 36.1 0.0 0.00033 20.6 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 OEU12898.1 - 5.4e-06 26.1 0.0 6.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 OEU12898.1 - 0.012 14.8 0.0 0.083 12.0 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein DpnII PF04556.12 OEU12899.1 - 0.011 15.1 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 DpnII restriction endonuclease TPR_7 PF13176.6 OEU12899.1 - 0.093 12.8 0.2 39 4.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU12899.1 - 0.8 9.7 3.0 18 5.3 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 OEU12900.1 - 4.7e-43 144.6 13.6 4.3e-08 32.7 0.0 10.7 10 0 0 10 10 10 9 PPR repeat PPR_2 PF13041.6 OEU12900.1 - 1.9e-41 140.0 15.4 3.4e-08 33.6 1.5 9.2 6 3 1 7 7 7 6 PPR repeat family PPR PF01535.20 OEU12900.1 - 5.7e-31 104.6 29.0 3.1e-06 27.1 0.0 13.2 11 3 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 OEU12900.1 - 6.1e-30 103.1 11.6 9.3e-07 28.8 0.8 7.2 5 3 2 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU12900.1 - 1.4e-07 31.2 0.1 0.057 12.8 0.0 3.3 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 OEU12900.1 - 0.00017 21.4 3.6 0.56 10.1 0.1 3.4 3 0 0 3 3 3 2 Mitochondrial ATPase expression MRP-S27 PF10037.9 OEU12900.1 - 0.0016 17.4 0.5 11 4.8 0.0 4.6 4 1 1 5 5 5 1 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 OEU12900.1 - 0.061 14.2 0.0 3.2 8.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU12900.1 - 0.11 12.6 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 OEU12901.1 - 0.00097 19.5 13.3 0.21 12.0 0.0 4.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU12901.1 - 0.0012 19.1 1.8 1.1 10.0 0.0 4.7 4 2 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 OEU12901.1 - 0.0021 17.8 6.0 0.068 12.9 3.4 3.1 1 1 2 3 3 3 2 Leucine rich repeat SR-25 PF10500.9 OEU12902.1 - 3.2 7.3 10.4 8 6.0 0.3 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 OEU12903.1 - 0.51 8.8 28.6 0.83 8.1 28.6 1.3 1 0 0 1 1 1 0 Macoilin family BET PF17035.5 OEU12903.1 - 0.64 10.2 4.2 0.2 11.8 0.9 1.9 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation BAG PF02179.16 OEU12904.1 - 2.1e-06 28.1 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 BAG domain DUF3328 PF11807.8 OEU12904.1 - 0.041 13.6 0.5 0.041 13.6 0.5 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3328) BRCT PF00533.26 OEU12905.1 - 0.0014 19.0 2.6 0.13 12.7 0.1 3.7 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OEU12905.1 - 0.019 15.4 8.1 0.1 13.0 0.1 4.8 4 1 0 4 4 4 0 BRCT domain, a BRCA1 C-terminus domain AOX PF01786.17 OEU12906.1 - 2.6e-13 50.1 0.2 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Alternative oxidase SR-25 PF10500.9 OEU12906.1 - 5.8 6.5 8.6 2.7 7.6 4.0 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein LRR_4 PF12799.7 OEU12907.1 - 0.00021 21.6 1.2 6.3 7.4 0.0 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU12907.1 - 0.0055 16.4 0.8 0.4 10.5 0.2 2.7 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 OEU12907.1 - 0.029 14.9 0.0 49 5.1 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat COX5B PF01215.19 OEU12907.1 - 0.25 11.0 0.1 5.5 6.7 0.0 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase subunit Vb DUF3439 PF11921.8 OEU12908.1 - 0.039 13.9 1.0 0.039 13.9 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF5011 PF16403.5 OEU12910.1 - 0.12 12.5 2.3 1.4 9.1 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5011) VHP PF02209.19 OEU12911.1 - 7.4e-08 32.3 6.2 7.4e-08 32.3 6.2 2.1 3 0 0 3 3 3 1 Villin headpiece domain GRP PF07172.11 OEU12911.1 - 7.6 7.3 8.9 0.37 11.5 1.3 2.9 2 0 0 2 2 2 0 Glycine rich protein family Ig_5 PF16681.5 OEU12912.1 - 0.054 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain HSF_DNA-bind PF00447.17 OEU12913.1 - 2e-05 25.1 1.7 0.00041 20.9 0.0 3.2 3 1 0 3 3 3 1 HSF-type DNA-binding BUD22 PF09073.10 OEU12913.1 - 0.0041 16.5 9.8 0.0041 16.5 9.8 2.5 2 0 0 2 2 2 2 BUD22 DUF2457 PF10446.9 OEU12913.1 - 0.0072 15.5 6.2 0.0072 15.5 6.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) SOG2 PF10428.9 OEU12914.1 - 0.95 8.6 14.7 1.1 8.4 14.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF285 PF03382.14 OEU12915.1 - 5.4e-207 675.0 104.3 3.5e-38 130.1 11.1 6.0 1 1 6 7 7 7 7 Mycoplasma protein of unknown function, DUF285 Cornichon PF03311.14 OEU12915.1 - 0.094 13.1 0.6 55 4.1 0.0 4.5 2 1 2 4 4 4 0 Cornichon protein Mt_ATP-synt_B PF05405.14 OEU12915.1 - 0.095 12.3 0.3 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1108 PF06531.11 OEU12915.1 - 2.6 8.4 6.2 3.3 8.1 0.2 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF1108) HSF_DNA-bind PF00447.17 OEU12916.1 - 5e-09 36.6 1.3 1.2e-08 35.5 0.1 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding BUD22 PF09073.10 OEU12916.1 - 0.0095 15.3 8.5 0.015 14.7 8.5 1.2 1 0 0 1 1 1 1 BUD22 DNA_pol_phi PF04931.13 OEU12916.1 - 0.0096 14.1 0.1 0.0096 14.1 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase phi TMEM51 PF15345.6 OEU12917.1 - 6.3e-05 22.9 0.4 0.00021 21.2 0.3 2.0 1 1 0 1 1 1 1 Transmembrane protein 51 FAM163 PF15069.6 OEU12917.1 - 0.022 15.2 0.8 0.076 13.5 0.8 2.0 1 0 0 1 1 1 0 FAM163 family SIT PF15330.6 OEU12917.1 - 0.023 15.1 0.6 0.091 13.2 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Sigma_reg_N PF13800.6 OEU12917.1 - 0.044 14.1 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal EphA2_TM PF14575.6 OEU12917.1 - 0.046 14.6 0.6 0.31 11.9 0.6 2.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 OEU12917.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 LST-1 protein DUF4381 PF14316.6 OEU12917.1 - 0.18 12.0 0.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Tad PF13400.6 OEU12917.1 - 0.79 10.1 0.0 0.79 10.1 0.0 2.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like AAA_5 PF07728.14 OEU12918.1 - 3.7e-16 59.4 2.4 1.7e-11 44.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 OEU12918.1 - 4.4e-13 48.9 1.8 4.4e-13 48.9 1.8 3.3 4 0 0 4 4 3 1 AAA lid domain Mg_chelatase PF01078.21 OEU12918.1 - 0.00013 21.5 0.3 0.00077 18.9 0.0 2.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 OEU12918.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 OEU12918.1 - 0.0027 18.2 4.6 0.018 15.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OEU12918.1 - 0.0073 16.6 0.1 0.043 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OEU12918.1 - 0.025 15.0 0.6 0.42 11.0 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OEU12918.1 - 0.046 13.4 0.0 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 OEU12918.1 - 0.064 13.0 6.2 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OEU12918.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 OEU12918.1 - 0.091 12.5 0.1 3.3 7.4 0.1 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_9 PF17871.1 OEU12918.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 0 AAA lid domain DAG_kinase_N PF14513.6 OEU12918.1 - 0.81 9.9 7.2 0.15 12.2 3.0 2.0 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus Sporozoite_P67 PF05642.11 OEU12918.1 - 2.2 6.3 6.6 3.6 5.6 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NIR_SIR PF01077.22 OEU12919.1 - 5.9e-44 149.4 0.1 3e-31 108.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OEU12919.1 - 9.6e-36 121.5 0.0 1.5e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain SH3_12 PF18129.1 OEU12923.1 - 0.0092 16.1 0.0 0.85 9.8 0.0 3.2 3 0 0 3 3 3 1 Xrn1 SH3-like domain Mucin PF01456.17 OEU12925.1 - 0.014 15.4 6.6 0.014 15.4 6.6 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4112 PF13430.6 OEU12925.1 - 0.063 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Git3 PF11710.8 OEU12925.1 - 1.3 8.8 8.1 0.09 12.5 3.0 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OEU12926.1 - 0.39 10.0 16.9 5.1 6.3 16.9 2.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) NFACT-R_1 PF05670.13 OEU12927.1 - 8.7e-33 113.2 0.3 1.3e-32 112.7 0.3 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 OEU12927.1 - 0.032 14.4 0.1 0.081 13.1 0.0 1.8 2 1 0 2 2 2 0 NFACT protein RNA binding domain UCMA PF17085.5 OEU12927.1 - 0.094 12.7 6.7 0.14 12.1 6.7 1.4 1 0 0 1 1 1 0 Unique cartilage matrix associated protein ABC_tran PF00005.27 OEU12929.1 - 4.8e-43 147.0 3.3 1.8e-27 96.5 1.1 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU12929.1 - 9.6e-17 61.7 9.1 3.4e-05 23.8 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU12929.1 - 1.6e-11 44.0 8.7 2.1e-06 27.3 4.1 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU12929.1 - 2.9e-08 34.3 0.2 9.9e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU12929.1 - 3.2e-07 30.0 0.1 0.029 14.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU12929.1 - 3.8e-06 26.9 0.1 0.0023 17.8 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 OEU12929.1 - 5.4e-06 26.3 0.2 0.036 13.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 OEU12929.1 - 3.7e-05 23.6 5.3 0.0024 17.6 1.5 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OEU12929.1 - 4.7e-05 23.7 0.1 0.29 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OEU12929.1 - 8.9e-05 22.1 0.2 0.024 14.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 OEU12929.1 - 0.00021 21.9 0.2 0.021 15.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 OEU12929.1 - 0.00024 20.9 0.4 0.28 10.9 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OEU12929.1 - 0.00057 20.2 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 OEU12929.1 - 0.0018 18.0 0.2 0.024 14.3 0.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 OEU12929.1 - 0.0018 18.4 0.2 0.41 10.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU12929.1 - 0.0025 18.4 0.2 0.99 10.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 OEU12929.1 - 0.0034 17.7 0.2 4.6 7.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Zeta_toxin PF06414.12 OEU12929.1 - 0.0034 16.7 0.2 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 OEU12929.1 - 0.004 17.1 1.4 0.11 12.3 0.3 2.7 2 1 0 2 2 2 1 NTPase NACHT PF05729.12 OEU12929.1 - 0.0043 17.0 1.0 0.11 12.5 0.0 2.8 2 1 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 OEU12929.1 - 0.0057 16.6 0.1 4.5 7.1 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OEU12929.1 - 0.0068 16.1 0.1 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 OEU12929.1 - 0.0088 16.1 2.6 4.8 7.2 0.0 3.9 2 2 2 4 4 4 0 AAA domain AAA PF00004.29 OEU12929.1 - 0.01 16.2 2.4 2.8 8.4 0.1 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 OEU12929.1 - 0.015 15.0 0.1 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 OEU12929.1 - 0.015 14.8 0.5 1.9 8.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain Phage-MuB_C PF09077.11 OEU12929.1 - 0.018 14.9 0.8 0.046 13.6 0.5 1.8 2 0 0 2 2 1 0 Mu B transposition protein, C terminal DUF815 PF05673.13 OEU12929.1 - 0.02 14.0 0.4 0.098 11.8 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 OEU12929.1 - 0.046 13.7 0.0 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OEU12929.1 - 0.052 13.8 1.8 2.3 8.4 0.2 3.2 3 1 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 OEU12929.1 - 0.054 12.5 0.5 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OEU12929.1 - 0.058 13.5 0.5 2.1 8.5 0.2 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 OEU12929.1 - 0.064 12.9 1.4 3.3 7.3 0.1 3.1 3 1 0 3 3 2 0 Thymidylate kinase Herpes_UL42 PF02282.16 OEU12929.1 - 0.067 13.1 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 1 0 DNA polymerase processivity factor (UL42) ATPase PF06745.13 OEU12929.1 - 0.11 11.8 2.3 6.2 6.1 0.2 2.8 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 OEU12929.1 - 0.17 12.2 2.0 4.3 7.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OEU12929.1 - 0.18 11.0 3.7 1.5 8.0 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 OEU12929.1 - 0.95 8.6 4.0 18 4.4 0.0 3.1 3 1 0 3 3 3 0 NB-ARC domain Pyr_redox_2 PF07992.14 OEU12930.1 - 2.5e-28 99.2 4.7 3.1e-28 98.9 4.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU12930.1 - 1.5e-18 67.1 0.5 4.3e-17 62.3 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU12930.1 - 7.8e-09 34.7 3.1 3.7e-05 22.6 0.2 3.6 3 1 1 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.24 OEU12930.1 - 8.5e-09 35.0 6.0 0.00013 21.2 0.8 3.3 1 1 3 4 4 4 2 FAD binding domain DAO PF01266.24 OEU12930.1 - 2.7e-08 33.8 4.2 0.00012 21.8 0.8 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OEU12930.1 - 4e-07 29.5 0.0 7.9e-06 25.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OEU12930.1 - 7e-07 28.7 2.6 0.012 14.7 0.6 3.2 2 1 1 3 3 3 3 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU12930.1 - 8.2e-07 28.7 0.2 1.5e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU12930.1 - 1.4e-06 28.4 0.1 3.5e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU12930.1 - 1e-05 26.0 6.1 0.00035 21.1 0.6 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU12930.1 - 0.00012 21.4 0.5 0.00053 19.3 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OEU12930.1 - 0.0092 15.1 0.7 0.15 11.0 0.4 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAGLU_N PF12971.7 OEU12930.1 - 0.038 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NAD_binding_9 PF13454.6 OEU12930.1 - 0.2 11.6 1.5 8.1 6.4 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU12931.1 - 2.8e-28 99.0 4.7 3.5e-28 98.7 4.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU12931.1 - 1.7e-18 67.0 0.5 4.8e-17 62.2 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU12931.1 - 7.7e-09 35.1 5.7 0.00014 21.1 0.8 3.3 1 1 3 4 4 4 2 FAD binding domain HI0933_like PF03486.14 OEU12931.1 - 8.8e-09 34.6 3.0 3.9e-05 22.5 0.2 3.6 3 1 1 4 4 4 3 HI0933-like protein DAO PF01266.24 OEU12931.1 - 2.6e-08 33.9 4.0 0.00013 21.7 0.8 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OEU12931.1 - 2.9e-07 30.0 0.0 6.2e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OEU12931.1 - 8e-07 28.5 2.6 0.012 14.7 0.6 3.2 2 1 1 3 3 3 3 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU12931.1 - 9.1e-07 28.6 0.2 1.6e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU12931.1 - 1.5e-06 28.3 0.1 3.7e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU12931.1 - 1e-05 26.0 6.0 0.00036 21.0 0.6 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU12931.1 - 0.00014 21.3 0.5 0.00058 19.2 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OEU12931.1 - 0.01 14.9 0.7 0.16 11.0 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAGLU_N PF12971.7 OEU12931.1 - 0.041 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NAD_binding_9 PF13454.6 OEU12931.1 - 0.2 11.6 1.3 8.4 6.4 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU12932.1 - 2.9e-28 99.0 4.7 3.6e-28 98.7 4.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU12932.1 - 1.7e-18 66.9 0.5 5e-17 62.1 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU12932.1 - 8e-09 35.1 5.7 0.00014 21.1 0.8 3.3 1 1 3 4 4 4 2 FAD binding domain HI0933_like PF03486.14 OEU12932.1 - 9.2e-09 34.5 3.0 3.9e-05 22.5 0.2 3.6 3 1 1 4 4 4 3 HI0933-like protein DAO PF01266.24 OEU12932.1 - 2.5e-08 33.9 3.9 0.00013 21.7 0.8 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OEU12932.1 - 3e-07 29.9 0.0 6.1e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OEU12932.1 - 8.3e-07 28.4 2.6 0.013 14.6 0.6 3.2 2 1 1 3 3 3 3 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU12932.1 - 9.4e-07 28.5 0.2 1.6e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU12932.1 - 1.5e-06 28.3 0.1 3.7e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU12932.1 - 1.1e-05 25.9 6.0 0.00036 21.0 0.6 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU12932.1 - 0.00013 21.3 0.4 0.00056 19.3 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OEU12932.1 - 0.01 14.9 0.7 0.16 11.0 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAGLU_N PF12971.7 OEU12932.1 - 0.041 13.6 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NAD_binding_9 PF13454.6 OEU12932.1 - 0.19 11.7 1.2 8.5 6.3 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding LYTB PF02401.18 OEU12933.1 - 5.5e-72 242.2 0.2 7e-72 241.8 0.2 1.1 1 0 0 1 1 1 1 LytB protein PFK PF00365.20 OEU12933.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase HCO3_cotransp PF00955.21 OEU12934.1 - 1.6e-108 363.8 17.5 1.3e-59 202.4 0.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family Carb_anhydrase PF00194.21 OEU12935.1 - 1.7e-11 44.1 2.0 1.6e-09 37.7 0.0 2.1 1 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Hexapep PF00132.24 OEU12936.1 - 4.1e-14 51.7 13.0 8.8e-06 25.3 0.7 4.3 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OEU12936.1 - 0.0009 18.9 7.7 0.39 10.5 0.1 4.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase RmlD_sub_bind PF04321.17 OEU12937.1 - 6.7e-13 48.4 0.0 1.5e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OEU12937.1 - 2.8e-11 43.3 0.0 4.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OEU12937.1 - 9.1e-07 28.3 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OEU12937.1 - 0.0051 16.3 0.0 0.022 14.2 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU12937.1 - 0.055 12.5 0.0 0.12 11.3 0.0 1.6 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OEU12937.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein ABC_membrane PF00664.23 OEU12938.1 - 1.3e-74 251.3 25.0 5e-38 131.3 11.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU12938.1 - 3e-69 231.8 1.1 2.6e-34 118.7 0.2 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OEU12938.1 - 1e-12 48.0 0.1 4.2e-05 23.1 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 OEU12938.1 - 8.7e-06 26.2 5.9 0.32 11.4 0.3 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OEU12938.1 - 2.9e-05 24.4 3.4 0.24 11.7 0.3 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OEU12938.1 - 0.00014 21.8 0.1 0.052 13.4 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase ABC_ATPase PF09818.9 OEU12938.1 - 0.00019 20.3 8.3 0.081 11.7 0.3 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OEU12938.1 - 0.00035 21.0 0.0 0.043 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OEU12938.1 - 0.00042 20.0 1.4 0.082 12.7 0.4 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain APS_kinase PF01583.20 OEU12938.1 - 0.00081 19.3 0.1 0.1 12.5 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 OEU12938.1 - 0.001 19.6 2.5 0.75 10.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.20 OEU12938.1 - 0.001 18.3 0.2 0.33 10.1 0.1 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 OEU12938.1 - 0.02 15.2 0.5 2.7 8.2 0.1 3.1 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 OEU12938.1 - 0.021 15.2 0.8 15 6.0 0.0 4.4 4 0 0 4 4 4 0 RNA helicase SbcCD_C PF13558.6 OEU12938.1 - 0.021 15.1 7.3 4.4 7.6 0.2 4.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OEU12938.1 - 0.037 13.8 0.6 11 5.6 0.1 3.2 3 1 0 3 3 3 0 AAA domain PRK PF00485.18 OEU12938.1 - 0.073 12.8 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2852 PF11014.8 OEU12938.1 - 0.085 13.0 0.2 2.4 8.4 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF4349 PF14257.6 OEU12938.1 - 0.1 12.0 0.4 4.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) AAA_5 PF07728.14 OEU12938.1 - 0.11 12.5 1.2 12 5.9 0.0 3.8 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) RXT2_N PF08595.11 OEU12938.1 - 3.6 7.6 11.2 0.21 11.6 2.3 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal AHD PF17793.1 OEU12939.1 - 0.14 12.0 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 ANC1 homology domain (AHD) WTF PF03303.13 OEU12941.1 - 6.1 6.5 7.3 2.5 7.7 0.7 2.0 1 1 1 2 2 2 0 WTF protein Reprolysin_3 PF13582.6 OEU12942.1 - 6.2e-05 23.5 1.5 7.9e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M11 PF05548.11 OEU12942.1 - 0.00016 21.0 0.1 0.00042 19.6 0.0 1.6 2 0 0 2 2 2 1 Gametolysin peptidase M11 Reprolysin_4 PF13583.6 OEU12942.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU12942.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 OEU12942.1 - 0.03 14.5 0.6 0.051 13.7 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12 PTase_Orf2 PF11468.8 OEU12945.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 SET PF00856.28 OEU12950.1 - 2.5e-06 28.0 0.0 3.1e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 SET domain AAL_decarboxy PF03306.13 OEU12950.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase OxoDH_E1alpha_N PF12573.8 OEU12951.1 - 0.081 12.7 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal HTH_50 PF18024.1 OEU12955.1 - 2.9e-13 49.2 4.1 8.8e-05 22.0 0.1 3.6 3 0 0 3 3 3 3 Helix-turn-helix domain HTH_8 PF02954.19 OEU12955.1 - 5.5e-08 32.5 6.2 0.0068 16.2 0.3 3.7 3 0 0 3 3 3 2 Bacterial regulatory protein, Fis family Abhydro_lipase PF04083.16 OEU12955.1 - 6.7e-06 25.6 0.7 1.3 8.6 0.0 3.6 3 0 0 3 3 3 3 Partial alpha/beta-hydrolase lipase region ETRAMP PF09716.10 OEU12955.1 - 0.003 17.6 0.1 0.003 17.6 0.1 4.1 3 2 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) HTH_AraC PF00165.23 OEU12955.1 - 0.013 15.5 0.1 12 6.1 0.0 3.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_29 PF13551.6 OEU12955.1 - 0.028 14.5 0.1 56 3.9 0.0 4.1 3 1 1 4 4 4 0 Winged helix-turn helix HTH_Crp_2 PF13545.6 OEU12955.1 - 0.096 12.7 0.6 23 5.0 0.1 2.8 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Trypan_PARP PF05887.11 OEU12958.1 - 0.18 11.8 3.6 0.25 11.3 3.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CTP_transf_like PF01467.26 OEU12959.1 - 2.6e-14 53.6 0.0 4.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HSF_DNA-bind PF00447.17 OEU12960.1 - 3.2e-18 66.1 0.1 3.4e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Gly_transf_sug PF04488.15 OEU12961.1 - 8.7e-06 26.3 0.3 1.5e-05 25.6 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU12961.1 - 0.00032 20.1 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Sigma_reg_N PF13800.6 OEU12965.1 - 0.056 13.7 0.5 0.056 13.7 0.5 2.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF3841 PF12952.7 OEU12966.1 - 0.018 14.8 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) FtsK_SpoIIIE_N PF12538.8 OEU12966.1 - 0.038 14.2 0.1 0.049 13.8 0.1 1.1 1 0 0 1 1 1 0 DNA transporter TFB6 PF17110.5 OEU12966.1 - 0.044 13.5 0.3 0.054 13.3 0.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH UIM PF02809.20 OEU12967.1 - 0.0016 18.2 3.9 0.0016 18.2 3.9 3.2 3 0 0 3 3 3 1 Ubiquitin interaction motif DUF1819 PF08849.11 OEU12967.1 - 0.037 13.8 2.4 0.18 11.6 0.7 2.2 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) Zn_Tnp_IS91 PF14319.6 OEU12967.1 - 0.091 12.8 0.5 0.36 10.9 0.5 2.0 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-FPG_IleRS PF06827.14 OEU12967.1 - 0.46 10.4 3.2 1 9.3 3.2 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Tudor_3 PF18115.1 OEU12968.1 - 0.00052 19.8 12.3 0.63 9.9 0.1 5.3 5 0 0 5 5 5 3 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 OEU12968.1 - 0.0021 18.5 19.5 2.5 8.6 0.2 5.4 5 0 0 5 5 5 3 Agenet domain Tudor_2 PF18104.1 OEU12968.1 - 0.0023 17.5 1.1 0.035 13.8 0.0 3.4 3 0 0 3 3 3 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 OEU12968.1 - 6.6 6.6 19.1 0.46 10.3 2.0 4.8 5 0 0 5 5 5 0 Lamin-B receptor of TUDOR domain Carb_anhydrase PF00194.21 OEU12969.1 - 8.9e-15 54.9 2.3 1e-06 28.5 0.0 3.9 3 1 1 4 4 4 3 Eukaryotic-type carbonic anhydrase APG9 PF04109.16 OEU12969.1 - 0.33 9.9 1.0 0.51 9.3 1.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg9 DUF5348 PF17295.2 OEU12970.1 - 0.017 15.0 7.8 0.12 12.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) PT PF04886.12 OEU12973.1 - 8.2e-17 60.5 83.5 1.8e+04 -34.8 83.5 4.8 1 1 0 1 1 1 0 PT repeat SR-25 PF10500.9 OEU12977.1 - 0.00022 20.9 9.4 0.00023 20.9 9.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SAP PF02037.27 OEU12977.1 - 0.093 12.5 0.4 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 SAP domain DNA_pol_phi PF04931.13 OEU12977.1 - 0.29 9.2 9.4 0.33 9.0 9.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Macoilin PF09726.9 OEU12977.1 - 1.6 7.2 7.7 1.7 7.1 7.7 1.0 1 0 0 1 1 1 0 Macoilin family NlpE PF04170.12 OEU12978.1 - 2.3 9.2 7.9 0.49 11.4 0.3 3.3 4 0 0 4 4 4 0 NlpE N-terminal domain SAE2 PF08573.10 OEU12978.1 - 3.2 8.9 0.0 3.2 8.9 0.0 4.0 4 0 0 4 4 4 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Cathelicidins PF00666.17 OEU12981.1 - 0.29 11.5 1.0 4.7 7.6 0.1 2.7 2 0 0 2 2 2 0 Cathelicidin Pepdidase_M14_N PF18027.1 OEU12982.1 - 0.021 15.2 4.3 0.087 13.2 4.2 2.1 1 1 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain RNA_pol_Rpb8 PF03870.15 OEU12983.1 - 0.096 12.9 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb8 DEAD PF00270.29 OEU12984.1 - 0.0025 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OEU12984.1 - 0.015 15.3 0.1 0.058 13.4 0.1 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sulfate_transp PF00916.20 OEU12987.1 - 0.016 14.0 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Sulfate permease family FMO-like PF00743.19 OEU12988.1 - 3.3e-14 52.2 0.1 4.6e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OEU12988.1 - 2.3e-09 36.9 0.0 4.7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU12988.1 - 1.2e-07 31.2 0.0 9.6e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OEU12988.1 - 3.5e-05 23.9 0.0 9.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU12988.1 - 0.00027 21.4 0.0 0.32 11.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU12988.1 - 0.00053 19.3 0.1 0.0018 17.6 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU12988.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pro_isomerase PF00160.21 OEU12989.1 - 4.9e-35 121.1 0.2 5.3e-35 121.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ABM PF03992.16 OEU12990.1 - 3.3e-18 65.6 0.4 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase TPR_11 PF13414.6 OEU12991.1 - 2.3e-15 56.0 4.1 2.1e-05 24.1 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 OEU12991.1 - 4e-15 54.9 2.5 7.5e-06 25.5 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU12991.1 - 3.9e-12 45.3 2.7 0.00065 19.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OEU12991.1 - 1e-06 29.2 1.7 0.058 13.9 0.3 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU12991.1 - 1.1e-06 28.4 2.9 0.026 14.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU12991.1 - 2.2e-06 27.6 1.7 0.0083 16.4 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU12991.1 - 8.2e-06 26.4 1.9 0.077 13.7 0.8 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU12991.1 - 0.00051 19.8 0.9 0.082 12.8 0.6 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU12991.1 - 0.00074 20.1 0.5 0.68 10.9 0.0 3.8 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU12991.1 - 0.0014 18.9 3.3 0.036 14.4 0.3 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU12991.1 - 0.0017 18.3 0.3 8.3 6.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU12991.1 - 0.0025 17.9 0.0 0.43 10.8 0.0 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 OEU12991.1 - 0.0051 16.7 6.2 0.22 11.5 0.4 2.8 2 1 1 3 3 3 2 STI1 domain TPR_6 PF13174.6 OEU12991.1 - 0.079 13.6 3.3 1.3 9.8 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 OEU12992.1 - 2.5e-28 97.8 1.7 2.8e-17 62.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein TPR_18 PF13512.6 OEU12992.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TBCA PF02970.16 OEU12993.1 - 0.00058 20.1 0.4 0.00077 19.7 0.4 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2150 PF09920.9 OEU12993.1 - 0.052 13.5 0.1 0.058 13.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) AAA_33 PF13671.6 OEU12994.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.11 OEU12995.1 - 0.0072 16.2 2.3 0.02 14.7 0.9 2.1 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Phage_TAC_3 PF06896.11 OEU12995.1 - 0.18 12.4 7.3 0.64 10.6 1.4 2.4 1 1 1 2 2 2 0 Phage tail assembly chaperone proteins, TAC Spc7 PF08317.11 OEU12995.1 - 0.45 9.3 9.6 0.13 11.2 1.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Uds1 PF15456.6 OEU12995.1 - 0.52 10.5 6.0 0.18 12.0 1.7 2.0 1 1 1 2 2 2 0 Up-regulated During Septation FAM76 PF16046.5 OEU12995.1 - 0.57 9.5 10.8 0.075 12.4 4.8 1.9 2 0 0 2 2 2 0 FAM76 protein LMBR1 PF04791.16 OEU12995.1 - 0.57 9.0 3.4 0.6 8.9 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Sporozoite_P67 PF05642.11 OEU12995.1 - 0.74 7.8 7.8 1 7.3 7.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1664 PF07889.12 OEU12995.1 - 1.7 8.7 5.8 0.48 10.5 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 OEU12995.1 - 3.2 7.8 11.1 2.6 8.1 0.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OEU12995.1 - 3.6 7.4 8.0 0.73 9.6 1.0 2.6 2 1 1 3 3 3 0 Septum formation initiator ClpS PF02617.17 OEU12998.1 - 0.063 13.1 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS RNA_pol_Rpb2_2 PF04561.14 OEU12998.1 - 0.14 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 HA PF03457.14 OEU13000.1 - 5e-13 49.2 1.5 5e-13 49.2 1.5 2.0 1 1 1 2 2 2 1 Helicase associated domain Mt_ATP-synt_B PF05405.14 OEU13001.1 - 0.041 13.5 1.4 0.098 12.3 1.4 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3663 PF12404.8 OEU13002.1 - 0.1 12.6 0.3 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Peptidase Phage_GPL PF05926.11 OEU13002.1 - 0.98 9.4 3.7 3.7 7.5 1.8 2.5 2 0 0 2 2 2 0 Phage head completion protein (GPL) Ribosomal_L36e PF01158.18 OEU13003.1 - 0.011 15.9 0.1 0.032 14.5 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein L36e MIS13 PF08202.11 OEU13004.1 - 0.11 11.8 0.9 0.19 11.0 0.9 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF805 PF05656.14 OEU13005.1 - 1.3 9.5 5.1 2.4 8.6 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF2838 PF10998.8 OEU13006.1 - 2.6e-19 69.5 11.4 2.6e-19 69.5 11.4 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) NIP_1 PF08995.10 OEU13007.1 - 0.033 14.6 0.9 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Necrosis inducing protein-1 DUF188 PF02639.14 OEU13007.1 - 0.2 11.3 1.2 1.1 8.9 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 GcpE PF04551.14 OEU13009.1 - 0.015 14.4 0.0 0.017 14.2 0.0 1.0 1 0 0 1 1 1 0 GcpE protein HTH_Tnp_1 PF01527.20 OEU13010.1 - 8.8e-06 25.9 1.3 8.8e-06 25.9 1.3 3.8 5 0 0 5 5 5 1 Transposase HTH_23 PF13384.6 OEU13010.1 - 0.036 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 OEU13010.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family His_Phos_1 PF00300.22 OEU13013.1 - 3.7e-32 111.6 0.0 2.8e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SPC12 PF06645.13 OEU13014.1 - 1.1e-25 89.5 2.5 1.3e-25 89.3 2.5 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MscL PF01741.18 OEU13015.1 - 0.056 13.8 1.8 0.069 13.5 0.3 2.0 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL PsaM PF07465.13 OEU13015.1 - 0.74 9.6 3.8 1.4 8.7 3.8 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) UCH PF00443.29 OEU13016.1 - 3.2e-43 148.1 0.1 4.2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OEU13016.1 - 2.5e-09 37.3 4.2 3.6e-09 36.8 0.2 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OEU13016.1 - 0.00014 21.6 0.4 0.0065 16.1 0.4 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YafQ_toxin PF15738.5 OEU13016.1 - 0.006 16.9 0.3 7.2 7.0 0.1 3.2 2 1 0 2 2 2 2 Bacterial toxin of type II toxin-antitoxin system, YafQ V-set PF07686.17 OEU13016.1 - 0.0095 16.1 0.0 0.054 13.7 0.0 2.2 3 0 0 3 3 3 1 Immunoglobulin V-set domain zf-C2H2 PF00096.26 OEU13016.1 - 3 8.5 5.5 5.8 7.6 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type GrpE PF01025.19 OEU13018.1 - 4.7e-29 101.2 4.0 1.6e-28 99.5 4.0 1.7 1 1 0 1 1 1 1 GrpE TPR_MLP1_2 PF07926.12 OEU13018.1 - 0.00034 20.7 1.4 0.00071 19.6 1.4 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein FAP206 PF12018.8 OEU13018.1 - 0.00038 20.1 0.8 0.00062 19.4 0.8 1.3 1 1 0 1 1 1 1 Domain of unknown function FliS PF02561.14 OEU13018.1 - 0.0028 17.9 0.6 0.012 15.9 0.6 2.0 1 1 0 1 1 1 1 Flagellar protein FliS HAUS4 PF14735.6 OEU13018.1 - 0.0037 17.0 0.3 0.0067 16.2 0.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 Tropomyosin_1 PF12718.7 OEU13018.1 - 0.037 14.2 4.2 0.078 13.1 4.2 1.6 1 0 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.20 OEU13018.1 - 0.041 13.8 1.3 0.13 12.3 1.3 1.8 1 1 0 1 1 1 0 Prefoldin subunit DUF572 PF04502.13 OEU13018.1 - 0.097 12.3 3.1 0.098 12.3 3.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CorA PF01544.18 OEU13018.1 - 0.13 11.5 1.4 0.19 11.0 0.6 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF5446 PF17522.2 OEU13018.1 - 1 9.6 4.7 0.99 9.6 2.5 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5446) Pkinase PF00069.25 OEU13019.1 - 5.7e-46 157.0 0.0 7.5e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13019.1 - 1.8e-28 99.5 0.0 2.3e-22 79.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU13019.1 - 0.02 13.7 0.0 0.12 11.2 0.0 1.9 1 1 1 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OEU13019.1 - 0.023 14.1 0.5 0.052 12.9 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OEU13019.1 - 0.034 13.8 0.1 2.7 7.6 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OEU13019.1 - 0.082 12.8 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 OEU13020.1 - 2e-53 180.3 0.0 2.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU13020.1 - 3.1e-28 98.4 0.0 4.7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU13020.1 - 2.6e-11 43.3 0.0 3.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OEU13020.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OEU13020.1 - 0.016 14.9 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OEU13020.1 - 0.018 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU13020.1 - 0.04 13.8 0.0 2.4 8.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 OEU13020.1 - 0.054 12.9 0.0 0.099 12.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OEU13020.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OEU13020.1 - 0.096 13.1 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OEU13020.1 - 0.18 10.9 0.1 0.5 9.5 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit EF-hand_7 PF13499.6 OEU13021.1 - 3.5e-12 46.6 0.7 3.7e-12 46.5 0.7 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU13021.1 - 1.1e-11 43.3 1.8 2.2e-05 23.7 1.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU13021.1 - 7e-10 38.0 1.3 0.00081 19.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU13021.1 - 4.4e-07 29.6 1.6 7.2e-05 22.6 1.6 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU13021.1 - 6.4e-06 25.4 0.4 0.0015 17.9 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 OEU13021.1 - 0.023 14.7 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 OEU13021.1 - 0.04 12.5 0.0 0.04 12.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 OEU13021.1 - 0.04 13.8 0.1 0.89 9.5 0.0 2.4 2 1 0 2 2 2 0 EF hand OST-HTH PF12872.7 OEU13021.1 - 0.051 13.4 0.0 2.3 8.1 0.0 2.0 1 1 1 2 2 2 0 OST-HTH/LOTUS domain Pkinase PF00069.25 OEU13022.1 - 6.2e-56 189.7 0.0 7e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13022.1 - 6.8e-26 91.1 0.0 9.5e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU13022.1 - 2.2e-06 27.2 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU13022.1 - 9.2e-05 22.5 0.0 0.0065 16.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU13022.1 - 0.00032 20.1 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OEU13022.1 - 0.0026 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 OEU13022.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family KH_8 PF17903.1 OEU13023.1 - 7.7e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain T6PP_N PF18572.1 OEU13023.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Ysc84 PF04366.12 OEU13023.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Las17-binding protein actin regulator Myc_N PF01056.18 OEU13024.1 - 0.036 14.0 1.3 0.045 13.6 1.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Phage_Orf51 PF06194.11 OEU13024.1 - 0.061 13.4 7.3 1.1 9.4 0.5 3.2 3 0 0 3 3 3 0 Phage Conserved Open Reading Frame 51 TraD_N PF12615.8 OEU13024.1 - 0.77 10.6 3.8 31 5.4 0.1 3.0 3 0 0 3 3 3 0 F sex factor protein N terminal Stm1_N PF09598.10 OEU13024.1 - 2.8 8.9 7.9 0.48 11.3 3.4 1.9 2 0 0 2 2 2 0 Stm1 OTCace_N PF02729.21 OEU13025.1 - 5.3e-41 140.1 0.0 8.3e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 OEU13025.1 - 4.2e-33 114.7 0.0 1.1e-32 113.3 0.0 1.7 2 1 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Yip1 PF04893.17 OEU13026.1 - 1.5e-12 47.6 21.2 3.4e-12 46.4 21.2 1.6 1 1 0 1 1 1 1 Yip1 domain Fer4_24 PF18109.1 OEU13026.1 - 0.011 15.9 0.9 0.021 15.1 0.1 1.9 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Fic PF02661.18 OEU13027.1 - 9.2e-11 42.5 0.0 2.5e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family zf-RING_2 PF13639.6 OEU13027.1 - 5.3e-07 29.9 10.3 1.5e-06 28.4 10.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU13027.1 - 0.00089 19.1 5.8 0.00089 19.1 5.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU13027.1 - 0.0015 18.3 10.1 0.0048 16.7 10.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU13027.1 - 0.0032 17.7 6.7 0.0097 16.2 6.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OEU13027.1 - 0.053 13.6 1.0 0.13 12.3 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 OEU13027.1 - 4.5 7.5 8.0 16 5.7 8.0 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 OEU13027.1 - 5.3 7.4 7.1 20 5.6 7.1 2.1 1 0 0 1 1 1 0 RING-like domain Proteasome PF00227.26 OEU13028.1 - 5.1e-14 52.2 0.2 6.8e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit TraX PF05857.11 OEU13028.1 - 0.0027 17.8 0.1 0.88 9.6 0.0 2.1 2 0 0 2 2 2 2 TraX protein LPMO_10 PF03067.15 OEU13029.1 - 1.4e-05 25.9 1.7 0.00021 22.0 0.2 2.8 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LRR_8 PF13855.6 OEU13030.1 - 2.8e-15 55.8 11.9 1.2e-07 31.4 1.4 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU13030.1 - 1.8e-11 44.1 14.1 0.0011 19.3 0.6 4.2 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU13030.1 - 5.1e-06 26.3 10.0 17 6.4 0.1 6.7 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU13030.1 - 6.1e-05 22.8 10.2 1.9 8.7 0.2 5.4 5 0 0 5 5 5 2 Leucine Rich repeat Phage_lysozyme2 PF18013.1 OEU13031.1 - 0.0092 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Phage tail lysozyme Tim17 PF02466.19 OEU13032.1 - 5.1e-06 26.8 2.0 0.08 13.3 0.2 3.1 3 1 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Sulfotransfer_4 PF17784.1 OEU13033.1 - 5.4e-09 36.2 1.0 1.1e-07 32.0 1.0 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU13033.1 - 0.0092 16.4 0.3 0.0092 16.4 0.3 2.8 2 2 1 3 3 3 1 Sulfotransferase family COX16 PF14138.6 OEU13033.1 - 7.2 7.2 6.0 19 5.8 5.0 2.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Tyr-DNA_phospho PF06087.12 OEU13034.1 - 7.9e-68 229.3 0.8 9e-68 229.1 0.8 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase NatB_MDM20 PF09797.9 OEU13035.1 - 2.2e-39 135.5 0.5 4.3e-39 134.5 0.5 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 OEU13035.1 - 1.4e-06 28.6 2.5 0.0058 17.3 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU13035.1 - 0.00073 20.0 2.1 1.2 9.7 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU13035.1 - 0.0028 17.8 1.0 7.7 6.8 0.0 4.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OEU13035.1 - 0.0058 17.2 2.2 7.1 7.5 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 OEU13035.1 - 0.043 12.7 0.0 0.095 11.6 0.0 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 OEU13035.1 - 0.044 13.9 0.9 0.46 10.7 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BCAS2 PF05700.11 OEU13036.1 - 2.8e-19 69.6 10.1 3.7e-19 69.3 10.1 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) SpoIID PF08486.10 OEU13036.1 - 0.27 11.8 2.7 0.52 10.9 2.7 1.8 1 1 0 1 1 1 0 Stage II sporulation protein FTR1 PF03239.14 OEU13037.1 - 8.6e-09 35.0 5.4 1.6e-08 34.1 5.4 1.5 1 1 0 1 1 1 1 Iron permease FTR1 family Myc_target_1 PF15179.6 OEU13037.1 - 0.0013 18.7 2.3 0.046 13.6 0.4 2.2 2 0 0 2 2 2 2 Myc target protein 1 Wzy_C PF04932.15 OEU13037.1 - 0.016 14.8 2.5 0.2 11.3 0.3 2.3 2 0 0 2 2 2 0 O-Antigen ligase MgtE PF01769.16 OEU13037.1 - 0.046 14.1 0.5 0.046 14.1 0.5 2.7 3 0 0 3 3 3 0 Divalent cation transporter SPC25 PF06703.11 OEU13037.1 - 0.31 10.8 3.4 1.4 8.7 1.7 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TctA PF01970.16 OEU13037.1 - 0.94 8.1 11.2 0.038 12.7 0.7 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family LRR_4 PF12799.7 OEU13038.1 - 1.4e-11 44.4 17.3 0.03 14.8 0.2 6.9 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13038.1 - 6.1e-10 38.7 14.6 0.0014 18.3 0.2 5.6 3 3 2 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 OEU13038.1 - 0.13 12.2 0.3 10 6.1 0.2 2.5 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Rcd1 PF04078.13 OEU13040.1 - 4.5e-125 416.2 0.9 5.1e-125 416.0 0.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like ABC_membrane PF00664.23 OEU13042.1 - 1.3e-54 185.7 23.8 2.7e-29 102.7 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU13042.1 - 1.2e-52 178.1 0.1 5.5e-30 104.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 OEU13042.1 - 1.5e-10 41.2 0.1 0.00038 20.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OEU13042.1 - 1.2e-07 31.3 0.2 0.016 14.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 OEU13042.1 - 3.9e-07 29.7 4.6 0.013 15.0 0.4 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OEU13042.1 - 6.2e-07 29.5 0.7 0.038 13.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OEU13042.1 - 1.4e-06 28.9 4.5 0.009 16.5 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OEU13042.1 - 4.6e-06 27.0 1.1 0.05 13.9 0.0 3.6 4 1 0 4 4 3 2 AAA domain Dynamin_N PF00350.23 OEU13042.1 - 4.6e-06 26.8 3.4 0.023 14.7 1.1 2.9 2 0 0 2 2 2 2 Dynamin family AAA_21 PF13304.6 OEU13042.1 - 2.4e-05 24.3 3.3 0.033 14.0 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OEU13042.1 - 3.1e-05 24.2 2.1 0.025 14.7 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 OEU13042.1 - 7.4e-05 23.2 0.3 0.17 12.3 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_7 PF12775.7 OEU13042.1 - 0.0013 18.3 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 OEU13042.1 - 0.0015 17.8 0.7 0.65 9.1 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA PF00004.29 OEU13042.1 - 0.0024 18.3 0.4 13 6.2 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OEU13042.1 - 0.0025 17.6 0.6 0.88 9.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 OEU13042.1 - 0.0026 17.0 0.4 0.82 8.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) cobW PF02492.19 OEU13042.1 - 0.0035 16.9 0.9 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OEU13042.1 - 0.0041 17.3 0.4 4.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 OEU13042.1 - 0.0052 16.8 0.3 2 8.4 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 OEU13042.1 - 0.0053 16.1 0.4 1.1 8.5 0.2 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family MeaB PF03308.16 OEU13042.1 - 0.0065 15.5 0.3 0.17 10.8 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 OEU13042.1 - 0.0068 16.4 0.0 5.9 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 OEU13042.1 - 0.0093 15.5 0.2 4 6.9 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B T2SSE PF00437.20 OEU13042.1 - 0.01 14.9 0.1 1.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 OEU13042.1 - 0.01 15.1 1.3 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 OEU13042.1 - 0.011 16.2 0.1 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU13042.1 - 0.014 15.3 0.5 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 OEU13042.1 - 0.017 15.0 1.1 4.4 7.2 0.2 2.6 2 0 0 2 2 2 0 NTPase GTP_EFTU PF00009.27 OEU13042.1 - 0.019 14.5 0.0 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.6 OEU13042.1 - 0.03 14.0 8.8 0.047 13.4 0.1 3.0 4 0 0 4 4 2 0 AAA ATPase domain RNA_helicase PF00910.22 OEU13042.1 - 0.036 14.4 1.0 20 5.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_27 PF13514.6 OEU13042.1 - 0.11 12.1 0.1 19 4.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OEU13042.1 - 0.12 11.2 0.3 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AIG1 PF04548.16 OEU13042.1 - 0.14 11.4 2.6 2.5 7.4 0.1 2.9 3 0 0 3 3 3 0 AIG1 family ATP-synt_ab PF00006.25 OEU13042.1 - 0.16 11.6 0.0 9.7 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 OEU13042.1 - 0.19 11.6 0.9 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase PTR2 PF00854.21 OEU13043.1 - 9.8e-45 153.0 12.3 3.6e-27 95.2 1.1 2.2 2 0 0 2 2 2 2 POT family RseC_MucC PF04246.12 OEU13043.1 - 0.14 12.1 9.5 1.1 9.2 0.3 3.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Methyltransf_12 PF08242.12 OEU13044.1 - 6.4e-05 23.6 1.1 0.00091 19.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UxaE PF16257.5 OEU13044.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 tagaturonate epimerase DUF4272 PF14094.6 OEU13045.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) BT1 PF03092.16 OEU13046.1 - 2.2e-34 118.6 16.0 3.1e-20 71.9 9.3 3.7 2 1 2 4 4 4 4 BT1 family FTO_NTD PF12933.7 OEU13050.1 - 2.9e-60 204.0 1.3 3.9e-37 128.0 0.3 2.2 1 1 1 2 2 2 2 FTO catalytic domain FTO_CTD PF12934.7 OEU13050.1 - 8.1e-29 100.6 3.5 1.2e-28 100.0 3.5 1.2 1 0 0 1 1 1 1 FTO C-terminal domain PAP_fibrillin PF04755.12 OEU13051.1 - 8.9e-07 29.0 0.0 0.00018 21.5 0.0 2.6 2 0 0 2 2 2 2 PAP_fibrillin Bmt2 PF11968.8 OEU13052.1 - 2.5e-37 128.8 1.1 1.6e-36 126.2 1.1 1.9 1 1 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_11 PF08241.12 OEU13052.1 - 4.2e-06 27.3 0.0 7.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU13052.1 - 1.1e-05 26.0 0.0 5.3e-05 23.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU13052.1 - 0.00035 20.4 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU13052.1 - 0.00039 21.1 0.0 0.00084 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU13052.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 OEU13052.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S22 PF08136.11 OEU13052.1 - 0.45 10.9 0.1 0.45 10.9 0.1 2.0 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family AAA PF00004.29 OEU13053.1 - 2e-10 41.2 0.1 2e-09 38.0 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU13053.1 - 1.7e-06 28.1 0.0 3.7e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU13053.1 - 2e-05 24.9 0.0 7.3e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU13053.1 - 3.1e-05 24.5 0.0 3.1e-05 24.5 0.0 3.5 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.12 OEU13053.1 - 3.8e-05 23.5 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OEU13053.1 - 5.2e-05 23.7 0.0 0.00024 21.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OEU13053.1 - 0.00048 20.2 0.0 0.02 14.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU13053.1 - 0.00064 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU13053.1 - 0.0011 19.1 0.8 0.0048 17.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 OEU13053.1 - 0.0035 17.3 1.5 0.0099 15.8 0.0 2.5 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_28 PF13521.6 OEU13053.1 - 0.0041 17.4 0.0 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OEU13053.1 - 0.006 16.9 0.0 0.027 14.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 OEU13053.1 - 0.012 15.4 0.0 0.054 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OEU13053.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 OEU13053.1 - 0.017 15.5 0.0 0.45 11.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OEU13053.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 OEU13053.1 - 0.023 14.2 0.1 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OEU13053.1 - 0.032 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OEU13053.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_assoc_2 PF16193.5 OEU13053.1 - 0.051 13.9 0.3 0.28 11.5 0.0 2.4 3 0 0 3 3 1 0 AAA C-terminal domain ATPase PF06745.13 OEU13053.1 - 0.057 12.8 0.0 2.9 7.2 0.0 2.7 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 OEU13053.1 - 0.07 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 OEU13053.1 - 0.091 12.3 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPD PF14811.6 OEU13054.1 - 3e-15 56.3 0.0 3e-15 56.3 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function TPD sequence-motif GREB1 PF15782.5 OEU13054.1 - 4.4 4.3 17.6 5.2 4.1 17.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_trans_4_5 PF16994.5 OEU13055.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 LRR_8 PF13855.6 OEU13057.1 - 4e-08 32.9 1.4 7.4e-05 22.4 0.1 2.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OEU13057.1 - 0.0034 17.8 1.9 0.38 11.3 0.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) SNARE_assoc PF09335.11 OEU13059.1 - 2.8e-21 76.2 5.5 2.8e-21 76.2 5.5 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein Phage_holin_2_3 PF16080.5 OEU13059.1 - 0.0041 16.8 0.7 0.0041 16.8 0.7 2.8 2 2 1 3 3 3 1 Bacteriophage holin family HP1 ABC_tran PF00005.27 OEU13060.1 - 9.6e-38 129.8 0.0 4.8e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU13060.1 - 5.7e-13 49.3 1.0 0.012 15.4 0.0 4.4 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU13060.1 - 3.7e-10 39.6 4.0 0.0029 17.1 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OEU13060.1 - 5e-07 29.8 0.0 0.0078 16.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OEU13060.1 - 3.3e-05 24.2 0.1 0.014 15.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OEU13060.1 - 3.3e-05 24.3 0.2 0.0086 16.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OEU13060.1 - 8.3e-05 22.6 0.3 0.16 11.9 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase NACHT PF05729.12 OEU13060.1 - 0.00014 21.8 0.7 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 OEU13060.1 - 0.00032 20.7 0.1 0.058 13.3 0.0 2.7 2 2 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 OEU13060.1 - 0.00033 21.1 0.0 0.24 11.8 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OEU13060.1 - 0.00056 19.7 0.3 0.22 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OEU13060.1 - 0.0006 20.4 0.2 0.14 12.6 0.2 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OEU13060.1 - 0.0011 18.4 0.1 0.64 9.3 0.1 2.5 2 0 0 2 2 2 2 KaiC AAA_33 PF13671.6 OEU13060.1 - 0.0019 18.4 0.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OEU13060.1 - 0.0027 18.0 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU13060.1 - 0.0037 17.8 0.0 3.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OEU13060.1 - 0.0042 16.7 1.9 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 OEU13060.1 - 0.0077 16.6 0.0 2.4 8.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 OEU13060.1 - 0.0091 16.0 0.2 0.49 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OEU13060.1 - 0.013 15.2 3.5 1.1 9.0 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 OEU13060.1 - 0.016 15.5 0.1 4.7 7.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 OEU13060.1 - 0.016 15.4 0.6 0.21 11.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 OEU13060.1 - 0.017 13.8 0.0 0.017 13.8 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OEU13060.1 - 0.022 14.5 2.0 1.3 8.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain Septin PF00735.18 OEU13060.1 - 0.039 13.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 OEU13060.1 - 0.041 13.1 0.0 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.11 OEU13060.1 - 0.05 13.3 4.6 2.4 7.9 0.0 3.2 3 0 0 3 3 3 0 Virulence-associated protein E TsaE PF02367.17 OEU13060.1 - 0.061 13.3 0.1 0.061 13.3 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF359 PF04019.12 OEU13060.1 - 0.08 12.6 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF359) DUF2950 PF11453.8 OEU13060.1 - 0.088 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) AAA_7 PF12775.7 OEU13060.1 - 0.11 12.1 0.1 4.4 6.8 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region DLIC PF05783.11 OEU13060.1 - 0.13 11.1 0.1 0.27 10.0 0.1 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 OEU13060.1 - 0.42 10.7 3.3 19 5.3 0.1 3.1 3 1 0 3 3 2 0 50S ribosome-binding GTPase RBFA PF02033.18 OEU13061.1 - 6e-14 52.4 0.1 7.5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A Proteasome PF00227.26 OEU13062.1 - 1.4e-49 168.2 0.5 1.8e-49 167.8 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit FmdA_AmdA PF03069.15 OEU13063.1 - 0.02 13.8 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Acetamidase/Formamidase family DUF3347 PF11827.8 OEU13063.1 - 0.42 10.8 10.3 0.53 10.5 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DltD PF04914.12 OEU13063.1 - 5.7 6.2 12.2 10 5.4 12.2 1.5 1 1 0 1 1 1 0 DltD protein ABC1 PF03109.16 OEU13064.1 - 7.7e-21 74.5 0.0 2.1e-20 73.1 0.0 1.7 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 OEU13064.1 - 0.001 19.0 0.1 0.0033 17.4 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 OEU13064.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Response_reg PF00072.24 OEU13065.1 - 1.5e-25 89.6 0.2 3.3e-25 88.4 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 OEU13065.1 - 1.7e-11 43.5 0.9 4.4e-11 42.2 0.5 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 OEU13065.1 - 0.025 14.2 0.4 0.083 12.6 0.4 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 OEU13065.1 - 0.043 13.6 0.2 0.57 10.0 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain RRP7 PF12923.7 OEU13066.1 - 2e-25 89.2 12.1 4.3e-25 88.2 12.1 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OEU13066.1 - 0.016 15.0 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain PH PF00169.29 OEU13067.1 - 6.4e-15 55.5 0.8 4.7e-11 43.1 0.1 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OEU13067.1 - 3e-05 24.4 7.1 0.12 12.8 1.1 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 OEU13067.1 - 0.0011 19.4 0.1 0.37 11.2 0.0 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3848 PF12959.7 OEU13067.1 - 0.041 13.9 2.8 0.11 12.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3848) Spt20 PF12090.8 OEU13068.1 - 2.3 7.8 28.5 0.013 15.1 8.4 2.4 2 0 0 2 2 2 0 Spt20 family ubiquitin PF00240.23 OEU13070.1 - 9.6e-92 300.8 18.7 1.8e-11 43.6 0.0 8.1 8 0 0 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.8 OEU13070.1 - 1.3e-40 137.0 13.7 6e-06 26.0 0.3 8.1 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU13070.1 - 2.7e-14 53.4 13.3 0.013 16.0 0.1 7.9 8 1 0 8 8 8 4 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU13070.1 - 3.5e-10 39.7 0.1 3.2 7.7 0.0 6.8 7 0 0 7 7 7 3 TANK binding kinase 1 ubiquitin-like domain TUG-UBL1 PF11470.8 OEU13070.1 - 2.5e-07 30.8 0.0 0.9 9.8 0.0 5.0 5 0 0 5 5 5 3 TUG ubiquitin-like domain UN_NPL4 PF11543.8 OEU13070.1 - 1.5e-05 25.4 1.9 0.7 10.4 0.1 5.6 6 1 1 7 7 6 2 Nuclear pore localisation protein NPL4 PI3K_rbd PF00794.18 OEU13070.1 - 2.3e-05 24.5 2.2 0.033 14.3 0.0 3.9 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain Rad60-SLD_2 PF13881.6 OEU13070.1 - 6.5e-05 23.0 3.8 1.3 9.2 0.0 5.0 5 2 1 6 6 6 2 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 OEU13070.1 - 7.3e-05 23.4 0.7 74 4.1 0.0 6.2 6 0 0 6 6 6 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_5 PF18037.1 OEU13070.1 - 0.00022 21.5 11.5 0.93 9.9 0.1 6.1 5 1 1 6 6 6 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU13070.1 - 0.0025 17.8 16.8 8.5 6.5 0.1 9.2 9 4 2 11 11 11 2 Ubiquitin-like domain UAE_UbL PF14732.6 OEU13070.1 - 0.0047 17.5 2.5 9.4 6.9 0.0 4.4 5 0 0 5 5 5 2 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Abhydrolase_1 PF00561.20 OEU13071.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold SelR PF01641.18 OEU13072.1 - 0.016 15.3 0.5 0.052 13.6 0.3 2.0 1 1 1 2 2 2 0 SelR domain zf-CCCH_4 PF18044.1 OEU13074.1 - 1.5e-08 34.3 6.5 3.3e-08 33.1 6.5 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger NUFIP1 PF10453.9 OEU13074.1 - 4.6e-08 32.8 0.9 4.6e-08 32.8 0.9 2.5 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 OEU13074.1 - 1.3e-07 31.3 3.7 1.3e-07 31.3 3.7 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU13074.1 - 2.7e-06 27.2 7.7 6.5e-06 26.0 7.7 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-met PF12874.7 OEU13074.1 - 9e-05 22.7 1.9 0.00014 22.1 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Torus PF16131.5 OEU13074.1 - 0.00022 21.9 3.8 0.00055 20.6 1.3 2.7 2 1 0 2 2 2 1 Torus domain zf-C2H2_jaz PF12171.8 OEU13074.1 - 0.0077 16.5 0.3 0.0077 16.5 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OEU13074.1 - 0.0084 16.1 0.8 0.0084 16.1 0.8 1.8 1 1 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OEU13074.1 - 0.07 14.0 4.4 2.7 9.1 1.0 2.9 1 1 1 2 2 2 0 C2H2-type zinc finger ANAPC_CDC26 PF10471.9 OEU13074.1 - 4.3 8.2 11.6 1.2 10.0 0.4 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Costars PF14705.6 OEU13075.1 - 1.3e-19 70.1 1.2 1.2e-18 67.1 0.2 2.3 2 0 0 2 2 2 1 Costars IQ PF00612.27 OEU13075.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif WD40 PF00400.32 OEU13077.1 - 9.6e-19 67.4 17.0 0.00013 22.7 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU13077.1 - 1.4e-15 57.3 1.9 6.5e-05 23.2 0.7 4.3 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU13077.1 - 2.8e-06 27.4 0.0 0.55 10.1 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OEU13077.1 - 0.00024 20.2 0.0 0.011 14.7 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OEU13077.1 - 0.19 10.0 0.0 0.32 9.3 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz SANT_DAMP1_like PF16282.5 OEU13079.1 - 2.3e-25 88.6 1.3 3.8e-25 87.9 1.3 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 OEU13079.1 - 8.8e-06 25.7 5.3 8.8e-06 25.7 5.3 3.0 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 OEU13079.1 - 0.037 14.2 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-CCHC PF00098.23 OEU13080.1 - 0.012 15.7 1.1 0.021 14.9 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_64 PF09258.10 OEU13081.1 - 1e-43 149.4 0.4 1.9e-41 142.0 0.4 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain FPL PF09758.9 OEU13082.1 - 6.9e-24 84.5 0.6 2.3e-23 82.8 0.3 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein CENP-B_dimeris PF09026.10 OEU13082.1 - 0.023 15.1 1.1 0.023 15.1 1.1 4.5 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Methyltransf_16 PF10294.9 OEU13083.1 - 3e-13 49.9 0.0 1.6e-09 37.8 0.0 2.6 3 0 0 3 3 3 2 Lysine methyltransferase Methyltransf_23 PF13489.6 OEU13083.1 - 1.6e-05 24.8 0.1 4.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU13083.1 - 0.22 12.3 9.4 0.51 11.1 3.5 3.6 3 1 0 3 3 3 0 Methyltransferase domain Mpv17_PMP22 PF04117.12 OEU13084.1 - 1.2e-13 51.1 3.1 2.4e-13 50.1 3.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family CaATP_NAI PF12515.8 OEU13084.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain Fip1 PF05182.13 OEU13085.1 - 8.2e-15 54.1 3.3 1.4e-14 53.3 3.3 1.4 1 0 0 1 1 1 1 Fip1 motif SASA PF03629.18 OEU13086.1 - 1.7e-21 76.9 0.0 7.5e-14 51.9 0.0 2.4 2 1 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Aminotran_4 PF01063.19 OEU13087.1 - 5.8e-17 62.3 0.2 5.5e-14 52.6 0.0 2.4 2 1 0 2 2 2 2 Amino-transferase class IV DUF3439 PF11921.8 OEU13087.1 - 0.035 14.1 3.2 0.08 12.9 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TFIIE-A_C PF11521.8 OEU13087.1 - 0.87 9.9 5.4 37 4.7 5.4 2.7 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Ribosomal_S19e PF01090.19 OEU13088.1 - 1.1e-52 177.4 0.0 1.2e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e AAA_22 PF13401.6 OEU13089.1 - 0.00023 21.4 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OEU13089.1 - 0.00047 19.3 0.0 0.00083 18.5 0.0 1.3 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 OEU13089.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.3 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 OEU13089.1 - 0.0019 17.9 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU13089.1 - 0.0063 16.9 0.0 0.007 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OEU13089.1 - 0.0071 16.9 0.0 0.0079 16.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OEU13089.1 - 0.023 15.1 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 OEU13089.1 - 0.025 14.2 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 OEU13089.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 OEU13089.1 - 0.038 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 OEU13089.1 - 0.056 14.0 0.0 0.084 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ala_racemase_C PF00842.21 OEU13089.1 - 0.08 12.8 0.1 0.43 10.4 0.1 1.9 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain RsgA_GTPase PF03193.16 OEU13089.1 - 0.097 12.6 0.1 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OEU13089.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 OEU13089.1 - 0.14 11.3 0.1 0.14 11.3 0.1 1.2 1 1 0 1 1 1 0 NB-ARC domain Pox_A32 PF04665.12 OEU13089.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Peptidase_S41 PF03572.18 OEU13089.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S41 Rad17 PF03215.15 OEU13089.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 1 0 1 1 1 0 Rad17 P-loop domain Aminotran_1_2 PF00155.21 OEU13090.1 - 1.5e-52 179.0 0.0 1.7e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SANT_DAMP1_like PF16282.5 OEU13090.1 - 0.015 15.5 0.3 0.052 13.8 0.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 CENP-B_dimeris PF09026.10 OEU13091.1 - 0.17 12.2 4.0 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF688 PF05097.12 OEU13091.1 - 0.21 10.7 6.2 0.45 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF688) MWFE PF15879.5 OEU13091.1 - 1.1 9.5 2.6 7.9 6.7 0.1 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit UPF0767 PF15990.5 OEU13091.1 - 8.1 6.7 6.1 2.2 8.5 0.4 2.7 3 0 0 3 3 3 0 UPF0767 family P33MONOX PF15302.6 OEU13092.1 - 0.0077 16.0 2.6 0.0084 15.9 2.6 1.1 1 0 0 1 1 1 1 P33 mono-oxygenase Epimerase PF01370.21 OEU13093.1 - 1.8e-20 73.4 0.1 2.1e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU13093.1 - 1.4e-15 57.0 0.3 1.7e-15 56.8 0.3 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OEU13093.1 - 6.4e-13 49.0 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OEU13093.1 - 2.1e-08 33.7 0.0 4e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OEU13093.1 - 5.1e-07 29.4 0.1 7.1e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OEU13093.1 - 9.4e-07 28.6 0.0 1.8e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 OEU13093.1 - 7.4e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OEU13093.1 - 0.00034 20.1 0.1 0.0012 18.3 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OEU13093.1 - 0.00072 18.8 0.1 0.0021 17.3 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF4567 PF15131.6 OEU13093.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) BRCT PF00533.26 OEU13094.1 - 0.0046 17.3 0.0 0.0046 17.3 0.0 2.4 2 2 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OEU13094.1 - 0.0082 16.5 0.4 0.0082 16.5 0.4 2.5 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain rRNA_proc-arch PF13234.6 OEU13095.1 - 3.6e-56 191.1 0.2 6.4e-56 190.2 0.2 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 OEU13095.1 - 1.2e-46 158.4 0.3 2.7e-46 157.2 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OEU13095.1 - 1.2e-17 64.3 0.3 6e-16 58.7 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU13095.1 - 9.4e-07 29.2 0.0 1.1e-05 25.7 0.0 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU13095.1 - 0.00033 20.7 0.0 0.0035 17.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OEU13095.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Latarcin PF10279.9 OEU13095.1 - 0.094 13.1 0.5 0.33 11.4 0.5 1.9 1 0 0 1 1 1 0 Latarcin precursor SYF2 PF08231.12 OEU13097.1 - 1.8e-15 57.7 16.9 5.6e-15 56.1 16.9 1.9 1 1 0 1 1 1 1 SYF2 splicing factor SAE2 PF08573.10 OEU13097.1 - 5.2 8.2 7.5 5.3 8.2 2.1 2.2 1 1 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Pro_isomerase PF00160.21 OEU13098.1 - 2.1e-38 132.1 0.9 2.4e-38 131.9 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PhyH PF05721.13 OEU13099.1 - 1.1e-06 29.1 0.1 2.5e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Vps16_N PF04841.13 OEU13100.1 - 2e-46 158.6 0.0 8.1e-40 136.8 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 OEU13100.1 - 2.2e-32 112.4 0.2 5.7e-32 111.0 0.2 1.6 1 1 0 1 1 1 1 Vps16, C-terminal region Hydrolase_4 PF12146.8 OEU13101.1 - 0.0018 17.6 0.2 1.5 8.0 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OEU13101.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OEU13101.1 - 0.038 14.6 0.0 0.05 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cullin PF00888.22 OEU13102.1 - 2e-21 76.3 0.1 3.2e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 OEU13102.1 - 1.2e-18 67.3 1.6 1.4e-18 67.2 0.1 1.9 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 PAS_6 PF08348.11 OEU13102.1 - 0.098 12.5 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 YheO-like PAS domain eIF3_N PF09440.10 OEU13103.1 - 1.5e-35 122.5 4.8 2.2e-35 122.0 1.2 2.7 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OEU13103.1 - 3.9e-14 53.0 0.0 1.3e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 PCI domain EzrA PF06160.12 OEU13103.1 - 0.012 13.8 0.7 3 5.9 0.1 2.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Xol-1_N PF09108.10 OEU13103.1 - 0.11 12.4 0.1 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal zf-H2C2_2 PF13465.6 OEU13104.1 - 0.36 11.3 4.8 5.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin PF00301.20 OEU13104.1 - 0.39 10.8 11.4 17 5.6 11.4 2.2 1 1 0 1 1 1 0 Rubredoxin ADK_lid PF05191.14 OEU13104.1 - 1.7 8.7 7.4 4.2 7.4 7.4 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-C2H2_3 PF13878.6 OEU13104.1 - 4.7 7.1 7.2 0.32 10.9 0.8 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO HA PF03457.14 OEU13106.1 - 0.017 15.5 1.4 0.093 13.1 1.4 2.3 1 1 0 1 1 1 0 Helicase associated domain Toxin_14 PF07829.11 OEU13106.1 - 0.17 11.8 0.7 0.31 11.0 0.7 1.4 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein DUF1635 PF07795.11 OEU13109.1 - 0.12 12.2 1.9 0.38 10.6 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4195 PF13836.6 OEU13109.1 - 0.17 11.9 9.2 0.32 11.1 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) RVT_2 PF07727.14 OEU13112.1 - 0.00012 21.9 0.1 0.00012 21.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.20 OEU13113.1 - 7.6e-22 77.3 0.2 7.6e-22 77.3 0.2 1.6 2 0 0 2 2 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU13113.1 - 1.5e-06 28.5 0.1 3.6e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU13113.1 - 1.5e-05 24.9 0.1 2.5e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 OEU13113.1 - 0.00011 21.6 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OEU13113.1 - 0.00015 21.9 0.1 0.00027 21.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU13113.1 - 0.00092 19.6 0.2 0.0025 18.2 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU13113.1 - 0.00094 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OEU13113.1 - 0.0068 16.1 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 OEU13113.1 - 0.0098 15.7 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredox_DsbH PF03190.15 OEU13113.1 - 0.03 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF953 PF06110.11 OEU13113.1 - 0.13 11.9 0.3 0.26 10.9 0.3 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) FeThRed_B PF02943.15 OEU13114.1 - 1.7e-34 118.0 2.0 2.3e-34 117.6 2.0 1.1 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain Mito_carr PF00153.27 OEU13115.1 - 3e-50 168.1 3.6 9e-17 60.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Radical_SAM PF04055.21 OEU13116.1 - 2.1e-11 44.5 0.0 5.4e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 OEU13116.1 - 9.7e-06 26.0 0.7 4.3e-05 23.9 0.3 2.1 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Carb_anhydrase PF00194.21 OEU13117.1 - 6.8e-14 52.0 0.0 2e-06 27.6 0.0 3.4 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 OEU13118.1 - 9.9e-16 58.0 0.6 1.4e-06 28.1 0.0 4.2 3 1 1 4 4 4 4 Eukaryotic-type carbonic anhydrase DENN PF02141.21 OEU13120.1 - 8.4e-33 113.9 0.2 1.8e-32 112.8 0.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain adh_short PF00106.25 OEU13121.1 - 8e-20 71.1 0.0 1.2e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU13121.1 - 2.3e-12 47.0 0.0 3.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Alpha_kinase PF02816.18 OEU13122.1 - 8.3e-32 110.8 0.2 1.2e-31 110.3 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family zf-MYND PF01753.18 OEU13123.1 - 4e-08 33.2 17.2 8.6e-08 32.1 17.2 1.6 1 0 0 1 1 1 1 MYND finger TPR_19 PF14559.6 OEU13123.1 - 0.00027 21.4 0.1 0.00097 19.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13123.1 - 0.0026 17.5 1.3 0.13 12.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU13123.1 - 0.025 14.6 0.2 6.8 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU13123.1 - 0.46 10.7 2.3 2.9 8.2 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-HIT PF04438.16 OEU13123.1 - 0.81 9.6 10.7 2.1 8.3 10.7 1.8 1 0 0 1 1 1 0 HIT zinc finger Radial_spoke PF04712.12 OEU13124.1 - 0.035 13.1 11.7 0.08 11.9 11.7 1.6 1 0 0 1 1 1 0 Radial spokehead-like protein FAM91_C PF14648.6 OEU13124.1 - 0.094 11.5 1.8 0.14 11.0 1.8 1.2 1 0 0 1 1 1 0 FAM91 C-terminus DUF4746 PF15928.5 OEU13124.1 - 0.36 10.2 15.1 0.88 8.9 15.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EIIBC-GUT_N PF03612.14 OEU13124.1 - 0.77 9.5 5.0 2.3 8.0 5.0 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RPN2_C PF18004.1 OEU13124.1 - 1.9 8.4 15.2 0.15 12.0 9.1 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 OEU13124.1 - 3 5.6 7.7 4.6 5.0 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 OEU13124.1 - 6.5 6.4 6.6 17 5.1 6.6 1.6 1 0 0 1 1 1 0 Connexin TAFII55_N PF04658.13 OEU13126.1 - 7.5e-21 74.5 0.0 7.5e-21 74.5 0.0 3.0 2 1 1 3 3 3 1 TAFII55 protein conserved region TAF4 PF05236.14 OEU13126.1 - 1.3e-05 25.1 6.6 1.3e-05 25.1 6.6 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DDHD PF02862.17 OEU13126.1 - 0.00059 20.1 6.3 0.46 10.6 3.7 2.2 2 0 0 2 2 2 2 DDHD domain PTPRCAP PF15713.5 OEU13126.1 - 0.0024 18.2 11.7 0.029 14.7 6.8 2.3 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated EPL1 PF10513.9 OEU13126.1 - 0.0071 16.7 12.1 0.91 9.9 0.1 2.3 2 0 0 2 2 2 2 Enhancer of polycomb-like Pex2_Pex12 PF04757.14 OEU13126.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Coilin_N PF15862.5 OEU13126.1 - 0.028 14.2 20.3 0.048 13.5 12.1 2.3 2 0 0 2 2 2 0 Coilin N-terminus ATP11 PF06644.11 OEU13126.1 - 0.11 12.3 19.4 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 ATP11 protein DUF4407 PF14362.6 OEU13126.1 - 0.11 11.8 4.9 0.02 14.2 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Connexin PF00029.19 OEU13126.1 - 0.15 11.8 8.8 0.08 12.7 2.9 2.2 2 0 0 2 2 2 0 Connexin RPOL_N PF14700.6 OEU13126.1 - 0.34 10.3 15.7 0.071 12.5 9.5 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal RR_TM4-6 PF06459.12 OEU13126.1 - 0.46 10.3 17.9 0.14 12.0 10.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 OEU13126.1 - 0.64 10.3 19.3 0.42 10.9 9.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) CPSF100_C PF13299.6 OEU13126.1 - 0.78 9.9 15.5 2.2 8.4 8.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Eapp_C PF10238.9 OEU13126.1 - 0.9 9.6 10.9 13 5.8 7.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein TMEM51 PF15345.6 OEU13126.1 - 1.2 9.0 11.0 0.27 11.0 3.5 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Rtf2 PF04641.12 OEU13126.1 - 1.3 8.3 21.6 9.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Zip PF02535.22 OEU13126.1 - 1.4 8.1 8.3 2.7 7.1 2.9 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Vfa1 PF08432.10 OEU13126.1 - 1.6 9.0 26.4 4.7 7.5 17.6 2.5 3 0 0 3 3 2 0 AAA-ATPase Vps4-associated protein 1 DAG_kinase_N PF14513.6 OEU13126.1 - 1.7 8.8 9.7 0.3 11.3 2.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus FAM60A PF15396.6 OEU13126.1 - 1.8 8.5 15.9 8.2 6.4 10.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Neur_chan_memb PF02932.16 OEU13126.1 - 2.5 8.1 7.1 2.5 8.1 3.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BRF1 PF07741.13 OEU13126.1 - 3 8.3 24.3 1.5 9.2 16.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain ALMT PF11744.8 OEU13126.1 - 3.2 6.5 10.4 1.3 7.8 4.4 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter ARF7EP_C PF14949.6 OEU13126.1 - 3.7 8.2 11.3 7.3 7.3 0.3 2.5 2 0 0 2 2 2 0 ARF7 effector protein C-terminus SLC12 PF03522.15 OEU13126.1 - 4.1 6.3 12.4 5.7 5.8 6.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Corazonin PF17308.2 OEU13126.1 - 4.3 7.7 15.3 0.064 13.6 4.8 2.3 2 1 0 2 2 2 0 Pro-corazonin DUF913 PF06025.12 OEU13126.1 - 4.4 6.2 7.8 5.4 5.9 3.7 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) XRN_M PF17846.1 OEU13126.1 - 4.7 6.0 12.2 0.79 8.6 5.9 2.0 2 0 0 2 2 2 0 Xrn1 helical domain TERB2 PF15101.6 OEU13126.1 - 5.2 7.1 11.5 10 6.1 8.4 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RP-C_C PF11800.8 OEU13126.1 - 6.6 6.8 16.3 47 4.0 0.1 2.9 2 1 0 2 2 2 0 Replication protein C C-terminal region Ctr PF04145.15 OEU13126.1 - 8.8 6.9 6.5 16 6.1 0.7 2.3 2 1 0 2 2 2 0 Ctr copper transporter family SR-25 PF10500.9 OEU13126.1 - 9.2 5.8 27.1 0.68 9.5 18.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2203 PF09969.9 OEU13126.1 - 9.4 7.0 0.0 9.4 7.0 0.0 3.2 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) MRG PF05712.13 OEU13128.1 - 0.0015 17.8 0.2 0.0028 17.0 0.2 1.4 1 0 0 1 1 1 1 MRG DUF2985 PF11204.8 OEU13128.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) PAD PF03068.15 OEU13130.1 - 0.024 13.7 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Ribonuc_red_lgC PF02867.15 OEU13131.1 - 2.3e-140 468.6 0.0 5.8e-116 388.1 0.0 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OEU13131.1 - 2.9e-22 78.5 0.0 5.8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OEU13131.1 - 2.6e-13 50.3 0.0 8.9e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain AreA_N PF07573.11 OEU13131.1 - 0.22 12.2 0.7 1.1 9.9 0.0 2.5 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus Matrilin_ccoil PF10393.9 OEU13132.1 - 4.2 7.3 6.0 1.1 9.2 0.2 3.1 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin VirE2 PF07229.12 OEU13133.1 - 0.022 13.4 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 VirE2 Fmp27_WPPW PF10359.9 OEU13134.1 - 0.035 13.0 8.3 0.042 12.7 8.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ALMT PF11744.8 OEU13134.1 - 0.16 10.8 3.6 0.18 10.6 3.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 OEU13134.1 - 0.22 11.3 3.3 0.26 11.1 3.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF5320 PF17253.2 OEU13134.1 - 9.9 7.3 10.0 22 6.2 10.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5320) AARP2CN PF08142.12 OEU13136.1 - 1.7e-09 37.7 0.0 6.1e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Melibiase_2 PF16499.5 OEU13139.1 - 7e-05 22.1 0.1 9.5e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Alpha galactosidase A LSM PF01423.22 OEU13140.1 - 3.4e-14 52.3 0.0 4.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OEU13140.1 - 0.00056 20.0 0.1 0.001 19.2 0.0 1.5 2 0 0 2 2 2 1 Ataxin 2 SM domain Tail_tube PF10618.9 OEU13140.1 - 0.11 12.4 0.0 0.91 9.4 0.1 2.0 1 1 1 2 2 2 0 Phage tail tube protein FAD_binding_3 PF01494.19 OEU13141.1 - 8.5e-06 25.2 0.1 1.4e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Ribonuc_L-PSP PF01042.21 OEU13141.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease L-PSP Kelch_4 PF13418.6 OEU13142.1 - 0.001 19.0 0.1 0.5 10.4 0.1 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OEU13142.1 - 0.0018 18.2 0.1 0.92 9.6 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 OEU13142.1 - 0.0022 18.2 0.1 2 8.8 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 OEU13142.1 - 0.012 15.2 0.0 5.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Kelch motif PK PF00224.21 OEU13144.1 - 1.3e-55 188.7 0.4 2.6e-42 145.0 0.1 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 OEU13144.1 - 4e-05 22.8 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GbpC PF08363.10 OEU13144.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucan-binding protein C Cellulase PF00150.18 OEU13145.1 - 0.0096 15.4 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Thymopoietin PF08198.11 OEU13145.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Thymopoietin protein UQ_con PF00179.26 OEU13146.1 - 5.7e-27 94.1 0.0 6.5e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OEU13146.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.6 1 1 1 2 2 2 0 UEV domain TPR_16 PF13432.6 OEU13149.1 - 0.00014 22.4 0.1 0.04 14.6 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU13149.1 - 0.00016 22.1 0.3 7.1 7.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU13149.1 - 0.00023 20.8 0.0 0.26 11.0 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 OEU13149.1 - 0.0024 18.1 0.0 0.48 10.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13149.1 - 0.0025 17.5 0.3 0.12 12.2 0.4 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU13149.1 - 0.0037 17.3 0.7 0.044 13.9 0.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU13149.1 - 0.021 15.0 0.7 0.46 10.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU13149.1 - 0.42 11.5 1.6 50 5.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.8 OEU13150.1 - 5.5e-05 23.3 4.5 5.5e-05 23.3 4.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OEU13150.1 - 0.00024 21.4 1.1 0.00027 21.2 1.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OEU13150.1 - 0.0015 18.9 3.8 0.0015 18.9 3.8 2.3 3 1 1 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OEU13150.1 - 0.072 14.0 0.9 0.072 14.0 0.9 2.0 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OEU13150.1 - 0.11 13.0 3.8 0.18 12.4 2.7 2.0 1 1 0 1 1 1 0 Zinc finger, C2H2 type Lactamase_B_2 PF12706.7 OEU13151.1 - 1e-39 136.2 0.0 1.1e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OEU13151.1 - 2.2e-21 76.4 0.0 2.6e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU13151.1 - 0.00047 20.2 0.4 0.0043 17.1 0.2 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF840 PF05801.11 OEU13152.1 - 0.16 12.1 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) SAM_PNT PF02198.16 OEU13153.1 - 0.014 15.4 0.6 1.6 8.7 0.2 2.6 1 1 1 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Pentapeptide_4 PF13599.6 OEU13153.1 - 0.071 13.3 9.0 0.39 10.9 9.0 2.0 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Phage_P2_GpE PF06528.12 OEU13153.1 - 0.25 10.9 0.0 30 4.3 0.0 2.3 2 0 0 2 2 2 0 Phage P2 GpE HIF-1 PF11413.8 OEU13153.1 - 5.9 6.4 15.1 85 2.7 0.1 6.3 2 2 1 3 3 3 0 Hypoxia-inducible factor-1 TagA PF12561.8 OEU13153.1 - 9.8 6.7 7.0 82 3.7 0.2 2.9 1 1 2 3 3 3 0 ToxR activated gene A lipoprotein domain 4HBT PF03061.22 OEU13154.1 - 5.4e-07 29.9 0.0 1.5e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily TRAUB PF08164.12 OEU13154.1 - 0.11 13.0 0.1 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal zf-RING_2 PF13639.6 OEU13157.1 - 0.83 10.0 15.4 1.8 8.9 15.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OEU13157.1 - 3.9 7.5 16.3 7.9 6.5 16.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Ntox33 PF15533.6 OEU13158.1 - 0.12 12.9 0.6 0.28 11.7 0.6 1.6 1 0 0 1 1 1 0 Bacterial toxin 33 Drf_GBD PF06371.13 OEU13159.1 - 0.015 14.9 0.8 0.015 14.9 0.8 2.4 3 1 0 3 3 3 0 Diaphanous GTPase-binding Domain PDZ_6 PF17820.1 OEU13159.1 - 0.024 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain CLIP_SPH_Scar PF18399.1 OEU13159.1 - 0.25 11.5 4.5 5.9 7.1 0.2 2.8 2 0 0 2 2 2 0 Clip-domain serine protease homolog Scarface Beta_helix PF13229.6 OEU13160.1 - 0.22 11.4 14.3 0.44 10.4 14.3 1.4 1 0 0 1 1 1 0 Right handed beta helix region Beta_helix PF13229.6 OEU13161.1 - 0.19 11.6 14.2 0.35 10.7 14.2 1.3 1 0 0 1 1 1 0 Right handed beta helix region DUF2866 PF11065.8 OEU13164.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) PseudoU_synth_2 PF00849.22 OEU13165.1 - 3e-21 76.2 0.2 7.2e-21 74.9 0.2 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase SUA5 PF03481.13 OEU13166.1 - 0.16 12.5 0.3 13 6.3 0.0 2.1 1 1 1 2 2 2 0 Putative GTP-binding controlling metal-binding Luciferase_cat PF10285.9 OEU13166.1 - 9.4 5.5 6.9 10 5.4 0.7 2.1 1 1 1 2 2 2 0 Luciferase catalytic domain Aa_trans PF01490.18 OEU13167.1 - 6.1e-47 160.2 22.0 5.6e-36 124.1 16.6 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU13167.1 - 7.4e-07 28.5 10.8 9.5e-07 28.2 10.2 1.5 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family CD99L2 PF12301.8 OEU13167.1 - 0.035 14.4 0.4 0.084 13.2 0.2 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF202 PF02656.15 OEU13168.1 - 5.3e-12 46.0 3.1 5.5e-12 46.0 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) NrsF PF06532.11 OEU13168.1 - 0.0041 16.9 3.0 0.0049 16.6 3.0 1.1 1 0 0 1 1 1 1 Negative regulator of sigma F Abhydrolase_9_N PF15420.6 OEU13168.1 - 0.02 14.9 1.2 0.023 14.7 1.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FixS PF03597.15 OEU13168.1 - 0.055 13.2 3.3 0.14 11.9 0.2 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Ni_hydr_CYTB PF01292.20 OEU13168.1 - 0.18 11.4 4.1 0.25 10.9 4.1 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 LRR_4 PF12799.7 OEU13170.1 - 2.7e-14 53.0 63.1 0.0011 19.4 0.9 8.3 6 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13170.1 - 4.1e-10 39.3 48.1 4.6e-06 26.3 2.6 6.3 2 1 7 9 9 9 8 Leucine rich repeat WW PF00397.26 OEU13171.1 - 7.9e-24 83.4 8.8 1.2e-11 44.5 3.8 2.1 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OEU13171.1 - 1e-05 25.8 2.2 0.023 15.0 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 OEU13171.1 - 0.00095 19.0 0.0 0.056 13.4 0.1 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.6 OEU13171.1 - 0.077 12.6 0.1 0.31 10.6 0.1 1.7 1 1 0 1 1 1 0 PQQ-like domain LRR_4 PF12799.7 OEU13173.1 - 3.7e-20 71.7 13.2 4.5e-07 30.1 0.7 4.8 2 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13173.1 - 1.9e-12 46.7 15.2 6.9e-05 22.5 1.7 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 OEU13173.1 - 4.6e-08 32.5 10.3 0.65 10.8 0.0 7.3 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 OEU13173.1 - 1.1e-06 28.2 11.7 4.2 7.7 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_2 PF07723.13 OEU13173.1 - 0.12 13.1 0.0 28 5.6 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat BBP2 PF07642.11 OEU13174.1 - 0.0022 17.2 0.3 0.0041 16.3 0.3 1.4 1 0 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 SNARE_assoc PF09335.11 OEU13175.1 - 8.9e-25 87.5 9.2 8.9e-25 87.5 9.2 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein CPP1-like PF11833.8 OEU13175.1 - 2.3 7.8 3.9 3.9 7.1 3.9 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NSP2_assoc PF14758.6 OEU13177.1 - 1.3 9.3 5.1 2.1 8.7 5.1 1.3 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein Dicty_REP PF05086.12 OEU13177.1 - 2.1 6.2 8.4 2.3 6.1 8.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HA2 PF04408.23 OEU13179.1 - 2.1 8.7 6.7 36 4.7 0.1 3.7 3 1 0 3 3 3 0 Helicase associated domain (HA2) RVT_2 PF07727.14 OEU13180.1 - 6.1e-05 22.8 0.0 8.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SOG2 PF10428.9 OEU13181.1 - 0.026 13.7 5.8 0.033 13.4 5.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 OEU13181.1 - 0.12 11.9 14.7 0.16 11.5 14.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.13 OEU13181.1 - 0.58 8.7 18.2 0.72 8.4 18.2 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 OEU13181.1 - 7.2 5.0 19.1 9.1 4.7 19.1 1.1 1 0 0 1 1 1 0 Macoilin family FapA PF03961.13 OEU13182.1 - 0.032 12.9 0.4 0.041 12.5 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ShK PF01549.24 OEU13183.1 - 0.054 14.0 7.2 0.054 14.0 7.2 3.0 2 2 0 2 2 2 0 ShK domain-like PT PF04886.12 OEU13183.1 - 0.085 12.4 19.9 3 7.4 0.2 2.6 2 1 0 2 2 2 0 PT repeat Conotoxin PF02950.17 OEU13183.1 - 7.3 7.7 14.8 0.21 12.6 4.3 2.2 1 1 1 2 2 2 0 Conotoxin Gly_rich PF12810.7 OEU13185.1 - 0.0044 17.0 1.4 0.0056 16.6 1.4 1.1 1 0 0 1 1 1 1 Glycine rich protein CtnDOT_TraJ PF07863.11 OEU13185.1 - 7.3 7.3 8.1 21 5.9 0.0 3.5 2 2 1 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon DUF866 PF05907.13 OEU13186.1 - 0.027 14.4 1.5 0.033 14.1 1.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Peptidase_S8 PF00082.22 OEU13187.1 - 2.3e-25 89.4 10.4 2.1e-18 66.6 0.0 3.3 4 0 0 4 4 4 2 Subtilase family P_proprotein PF01483.20 OEU13187.1 - 1.4e-08 34.6 0.0 9.1e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Proprotein convertase P-domain BUD22 PF09073.10 OEU13187.1 - 0.22 10.8 10.9 0.36 10.1 10.9 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OEU13187.1 - 1.2 8.5 14.3 2 7.8 14.3 1.3 1 0 0 1 1 1 0 SDA1 PUB PF09409.10 OEU13188.1 - 0.0019 18.1 0.3 0.0069 16.3 0.3 2.0 1 1 0 1 1 1 1 PUB domain DUF4140 PF13600.6 OEU13188.1 - 0.071 13.6 1.4 0.13 12.7 1.4 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YL1_C PF08265.11 OEU13189.1 - 0.054 13.3 0.2 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain Lycopene_cycl PF05834.12 OEU13190.1 - 1.6e-61 208.5 0.0 2.6e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OEU13190.1 - 2.8e-05 23.5 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OEU13190.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU13190.1 - 0.012 14.9 0.1 0.075 12.3 0.0 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU13190.1 - 0.046 14.0 0.1 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OEU13190.1 - 0.051 13.6 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OEU13190.1 - 0.076 12.6 0.1 0.84 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU13190.1 - 0.088 11.9 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_4 PF01565.23 OEU13191.1 - 5.4e-25 87.7 0.0 9.3e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 OEU13191.1 - 3.6e-16 59.8 0.1 3.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Peripla_BP_4 PF13407.6 OEU13192.1 - 1.9e-13 50.6 11.8 7.6e-11 42.1 3.0 4.5 2 2 0 2 2 2 2 Periplasmic binding protein domain GDP_Man_Dehyd PF16363.5 OEU13193.1 - 1e-60 205.9 0.0 2.7e-60 204.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU13193.1 - 8.7e-52 176.0 0.0 1.4e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU13193.1 - 9.3e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU13193.1 - 5.2e-16 58.6 0.0 3.5e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU13193.1 - 3.6e-10 39.4 0.0 5.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OEU13193.1 - 3.3e-08 33.0 0.0 5.9e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OEU13193.1 - 8.9e-05 22.5 0.0 0.0003 20.7 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OEU13193.1 - 0.001 18.6 0.0 0.0036 16.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OEU13193.1 - 0.0011 18.8 0.0 0.0039 17.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OEU13193.1 - 0.04 14.2 0.0 0.28 11.5 0.0 2.3 1 1 0 1 1 1 0 TrkA-N domain Chloroa_b-bind PF00504.21 OEU13194.1 - 1.3e-12 48.5 2.0 1.1e-06 29.2 0.2 2.2 1 1 2 3 3 3 3 Chlorophyll A-B binding protein Cu-oxidase_3 PF07732.15 OEU13196.1 - 3.9e-11 43.0 0.6 1.8e-10 40.9 0.4 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OEU13196.1 - 1.4e-09 37.9 2.4 9.1e-07 28.7 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase DAO PF01266.24 OEU13197.1 - 1.9e-20 73.8 0.0 3.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU13197.1 - 1.4e-05 24.6 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OEU13197.1 - 1.7e-05 24.9 0.0 5.7e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU13197.1 - 4e-05 23.0 0.0 5.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU13197.1 - 0.00025 20.2 0.1 0.00048 19.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OEU13197.1 - 0.00076 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 OEU13197.1 - 0.002 16.8 0.0 0.0028 16.3 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 OEU13197.1 - 0.002 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 OEU13197.1 - 0.012 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OEU13197.1 - 0.013 14.4 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 OEU13197.1 - 0.033 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OEU13197.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Collagen PF01391.18 OEU13198.1 - 0.67 9.8 11.2 22 4.9 11.2 2.3 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) ABC_tran PF00005.27 OEU13199.1 - 8e-47 159.2 0.0 3.7e-22 79.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU13199.1 - 5e-19 69.2 3.0 4.9e-09 36.4 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU13199.1 - 7.1e-10 38.7 7.6 0.0064 16.0 0.0 4.4 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU13199.1 - 1.3e-07 31.7 0.2 0.0097 16.0 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 OEU13199.1 - 1.3e-06 28.4 1.4 2.1e-06 27.7 0.7 1.7 2 0 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 OEU13199.1 - 1.6e-05 24.8 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OEU13199.1 - 5.4e-05 22.9 2.7 0.15 11.8 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OEU13199.1 - 0.00012 21.9 0.5 0.13 12.0 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OEU13199.1 - 0.00015 22.0 2.5 0.013 15.8 0.1 3.4 2 2 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 OEU13199.1 - 0.00023 21.1 0.0 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 OEU13199.1 - 0.00024 21.5 0.0 0.097 13.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 OEU13199.1 - 0.00042 20.7 0.0 1 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 OEU13199.1 - 0.00077 18.5 0.0 0.53 9.2 0.0 2.6 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 OEU13199.1 - 0.0008 20.0 7.6 0.35 11.3 1.2 2.8 2 1 0 2 2 2 2 AAA domain KAP_NTPase PF07693.14 OEU13199.1 - 0.00086 18.6 0.6 0.67 9.1 0.0 3.5 4 0 0 4 4 4 1 KAP family P-loop domain ATP-synt_ab PF00006.25 OEU13199.1 - 0.0012 18.5 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 OEU13199.1 - 0.0037 16.6 0.2 1 8.6 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 OEU13199.1 - 0.0038 17.0 0.7 1.2 8.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 OEU13199.1 - 0.0055 16.9 0.1 3.6 7.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 OEU13199.1 - 0.0069 16.8 0.0 2.1 8.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OEU13199.1 - 0.0096 15.1 3.8 0.24 10.6 0.1 2.8 2 2 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 OEU13199.1 - 0.012 15.6 1.1 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 OEU13199.1 - 0.014 14.9 0.1 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 OEU13199.1 - 0.019 15.5 1.0 4 8.0 0.1 3.2 3 1 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OEU13199.1 - 0.02 14.9 0.8 0.13 12.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OEU13199.1 - 0.022 15.0 2.9 0.42 10.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OEU13199.1 - 0.022 14.5 2.5 1 9.1 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 OEU13199.1 - 0.024 14.7 0.5 3.1 7.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 OEU13199.1 - 0.026 14.0 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 OEU13199.1 - 0.055 13.5 0.1 12 5.9 0.0 2.7 3 0 0 3 3 2 0 Dynamin family NTPase_1 PF03266.15 OEU13199.1 - 0.06 13.3 2.8 7.8 6.4 0.0 3.0 3 0 0 3 3 3 0 NTPase DUF87 PF01935.17 OEU13199.1 - 0.13 12.4 3.8 8.4 6.4 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain PRK PF00485.18 OEU13199.1 - 0.15 11.8 0.3 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 OEU13199.1 - 0.18 11.4 0.5 11 5.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 OEU13199.1 - 0.18 11.4 0.9 4.1 7.0 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 OEU13199.1 - 0.2 12.0 2.5 4.9 7.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 OEU13199.1 - 0.21 11.9 7.0 3.8 7.8 0.1 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 OEU13199.1 - 0.25 11.7 2.3 23 5.3 0.2 3.3 3 0 0 3 3 3 0 AAA domain ExbD PF02472.16 OEU13200.1 - 1.3 9.2 6.4 0.22 11.7 0.7 2.3 2 1 0 2 2 2 0 Biopolymer transport protein ExbD/TolR GCIP PF13324.6 OEU13200.1 - 1.5 8.4 7.8 0.57 9.7 1.7 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PhetRS_B1 PF18262.1 OEU13200.1 - 1.6 9.0 5.1 0.34 11.2 0.9 2.0 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain FAM176 PF14851.6 OEU13200.1 - 2.1 8.0 10.8 3.4 7.3 0.7 2.6 3 0 0 3 3 3 0 FAM176 family E7 PF00527.18 OEU13200.1 - 2.9 8.1 6.0 26 5.1 0.7 2.6 2 0 0 2 2 2 0 E7 protein, Early protein GP67 PF17634.2 OEU13200.1 - 6.2 7.3 19.2 1.1 9.7 5.3 2.5 2 0 0 2 2 2 0 Gene product 67 Ribosomal_60s PF00428.19 OEU13201.1 - 0.0045 17.5 2.7 0.0045 17.5 2.7 3.9 4 1 0 4 4 4 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 OEU13201.1 - 0.014 16.2 1.8 0.014 16.2 1.8 5.4 3 2 1 4 4 4 0 Putative WW-binding domain and destruction box CENP-B_dimeris PF09026.10 OEU13201.1 - 0.86 10.0 0.0 0.86 10.0 0.0 5.4 3 1 2 5 5 5 0 Centromere protein B dimerisation domain Keratin_2_head PF16208.5 OEU13202.1 - 1.7 8.8 9.9 2.3 8.3 9.9 1.1 1 0 0 1 1 1 0 Keratin type II head AAA_23 PF13476.6 OEU13203.1 - 0.00046 20.8 0.2 0.00064 20.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU13203.1 - 0.0037 16.6 0.1 0.0083 15.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 OEU13203.1 - 0.0066 16.2 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU13203.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OEU13203.1 - 0.015 15.8 0.0 0.047 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OEU13203.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OEU13203.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 OEU13203.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 OEU13203.1 - 0.061 12.1 0.1 0.094 11.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 OEU13203.1 - 0.094 12.6 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain EF-hand_4 PF12763.7 OEU13204.1 - 8.3e-07 28.9 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Kinetochor_Ybp2 PF08568.10 OEU13204.1 - 0.65 8.4 2.6 0.93 7.9 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Hamartin PF04388.12 OEU13204.1 - 0.7 8.5 19.5 0.9 8.1 19.5 1.1 1 0 0 1 1 1 0 Hamartin protein LMF1 PF06762.14 OEU13205.1 - 4.3e-75 253.5 16.2 1.1e-41 143.5 0.0 3.4 3 2 0 3 3 3 2 Lipase maturation factor CDC45 PF02724.14 OEU13205.1 - 9.2e-05 20.9 0.6 0.0017 16.7 0.4 2.2 2 0 0 2 2 2 1 CDC45-like protein Apt1 PF10351.9 OEU13205.1 - 0.00089 18.2 5.2 0.0024 16.8 0.8 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain U79_P34 PF03064.16 OEU13205.1 - 0.0049 16.3 1.7 0.0055 16.1 0.1 1.8 2 0 0 2 2 2 1 HSV U79 / HCMV P34 Pex14_N PF04695.13 OEU13205.1 - 0.0052 17.4 4.0 0.25 12.0 0.1 2.9 3 0 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region YL1 PF05764.13 OEU13205.1 - 0.0087 16.2 7.2 0.0087 16.2 7.2 2.6 3 0 0 3 3 2 1 YL1 nuclear protein CPSF100_C PF13299.6 OEU13205.1 - 0.024 14.8 10.7 0.039 14.1 1.2 2.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 OEU13205.1 - 0.052 12.5 2.6 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 OEU13205.1 - 0.056 12.6 9.3 0.29 10.3 0.6 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF962 PF06127.11 OEU13205.1 - 0.083 13.0 0.1 0.55 10.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) RRN3 PF05327.11 OEU13205.1 - 0.14 10.7 5.7 0.26 9.8 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ETRAMP PF09716.10 OEU13205.1 - 0.21 11.7 0.1 0.21 11.7 0.1 3.5 4 0 0 4 4 3 0 Malarial early transcribed membrane protein (ETRAMP) SDA1 PF05285.12 OEU13205.1 - 0.31 10.4 19.6 2.5 7.5 11.6 3.1 3 0 0 3 3 3 0 SDA1 FAM176 PF14851.6 OEU13205.1 - 0.33 10.6 13.3 0.3 10.7 0.5 3.4 3 0 0 3 3 3 0 FAM176 family CAC1F_C PF16885.5 OEU13205.1 - 0.83 9.2 7.6 0.37 10.4 0.7 2.2 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Sas10_Utp3 PF04000.15 OEU13205.1 - 0.87 10.3 5.4 0.21 12.2 0.3 2.6 2 1 1 3 3 3 0 Sas10/Utp3/C1D family FAM60A PF15396.6 OEU13205.1 - 0.92 9.5 7.0 2.9 7.8 4.4 2.4 2 0 0 2 2 2 0 Protein Family FAM60A HNF-1_N PF04814.13 OEU13205.1 - 2.2 8.9 10.9 1.8 9.2 0.7 2.9 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF3671 PF12420.8 OEU13205.1 - 5.4 7.1 6.2 2.3 8.3 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function FCP1_C PF09309.10 OEU13205.1 - 8.3 6.2 17.3 3.7 7.3 11.3 2.3 2 0 0 2 2 2 0 FCP1, C-terminal Striatin PF08232.12 OEU13205.1 - 9.8 6.8 11.2 51 4.4 7.1 2.5 2 0 0 2 2 2 0 Striatin family Beta-lactamase PF00144.24 OEU13206.1 - 7.7e-10 38.5 0.0 9e-09 35.0 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase Trypan_PARP PF05887.11 OEU13206.1 - 0.022 14.7 1.5 0.037 14.0 1.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Methyltransf_2 PF00891.18 OEU13208.1 - 1.8e-22 79.7 0.0 2.4e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 OEU13208.1 - 3.5e-05 24.5 0.1 0.00014 22.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU13208.1 - 0.071 13.8 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OEU13208.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ABC_tran PF00005.27 OEU13209.1 - 6.9e-37 127.0 0.1 3.5e-23 82.6 0.0 2.8 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OEU13209.1 - 4.7e-11 43.0 0.3 0.0012 18.7 0.0 3.7 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU13209.1 - 1e-05 25.1 0.1 0.16 11.4 0.1 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OEU13209.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OEU13209.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Choline_kinase PF01633.20 OEU13211.1 - 0.00022 20.9 0.1 0.00022 20.9 0.1 2.4 3 0 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.23 OEU13211.1 - 0.0024 17.8 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU13211.1 - 0.022 14.4 1.6 0.03 13.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Orf78 PF06024.12 OEU13212.1 - 4.2 7.7 6.3 7.6 6.9 6.3 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Peptidase_M15 PF01427.17 OEU13213.1 - 0.0066 16.2 0.0 0.9 9.2 0.0 2.7 1 1 1 2 2 2 2 D-ala-D-ala dipeptidase DASH_Ask1 PF08655.10 OEU13213.1 - 0.05 13.5 0.0 4.1 7.4 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Ask1 zf-Sec23_Sec24 PF04810.15 OEU13214.1 - 8.3e-12 45.0 0.2 1.9e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_trunk PF04811.15 OEU13214.1 - 2.8e-11 43.5 0.0 5.8e-10 39.1 0.0 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OEU13214.1 - 8.2e-05 23.3 0.0 0.0002 22.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OEU13214.1 - 0.013 15.3 0.7 0.05 13.4 0.1 2.4 2 1 0 2 2 2 0 Sec23/Sec24 helical domain Mon1 PF03164.14 OEU13215.1 - 7.4e-67 226.2 0.0 3.5e-58 197.6 0.2 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 DUF4834 PF16118.5 OEU13216.1 - 1.4 9.9 4.6 22 6.1 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) MttA_Hcf106 PF02416.16 OEU13217.1 - 1.4e-06 27.5 0.8 2.2e-06 26.9 0.8 1.4 1 0 0 1 1 1 1 mttA/Hcf106 family DUF3678 PF12435.8 OEU13217.1 - 0.13 11.6 1.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Pescadillo_N PF06732.11 OEU13218.1 - 1.7e-92 309.8 0.0 3.3e-92 308.9 0.0 1.4 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 OEU13218.1 - 0.00015 22.1 0.0 0.00038 20.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GCIP PF13324.6 OEU13218.1 - 6.4 6.3 8.8 11 5.5 8.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PseudoU_synth_2 PF00849.22 OEU13219.1 - 5.2e-30 104.6 0.1 8.6e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase sCache_2 PF17200.4 OEU13219.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Single Cache domain 2 PA14 PF07691.12 OEU13219.1 - 1.3 8.9 3.1 2.1 8.2 0.0 2.4 3 0 0 3 3 3 0 PA14 domain UCH PF00443.29 OEU13220.1 - 1.5e-27 96.8 0.2 2.2e-27 96.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU13220.1 - 0.00023 20.9 0.0 0.035 13.7 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Androgen_recep PF02166.16 OEU13220.1 - 0.69 8.7 3.9 0.9 8.3 3.9 1.2 1 0 0 1 1 1 0 Androgen receptor PRMT5_TIM PF17285.2 OEU13221.1 - 0.075 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 PRMT5 TIM barrel domain Yip1 PF04893.17 OEU13221.1 - 1.5 8.5 14.2 0.75 9.5 0.4 3.2 3 1 0 3 3 3 0 Yip1 domain SAYSvFN PF10260.9 OEU13222.1 - 6.5e-14 51.6 1.9 8e-14 51.3 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved domain (SAYSvFN) Sarcoglycan_1 PF04790.13 OEU13222.1 - 0.16 11.3 0.8 0.26 10.6 0.8 1.4 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein RMI1_N PF08585.12 OEU13222.1 - 3.3 7.4 9.9 9.9 5.9 10.0 1.7 1 1 0 1 1 1 0 RecQ mediated genome instability protein FAM60A PF15396.6 OEU13222.1 - 6.9 6.6 8.2 10 6.0 8.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A STN1_2 PF09170.10 OEU13223.1 - 0.00025 21.3 2.3 0.00048 20.4 2.3 1.4 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 OEU13223.1 - 0.015 15.2 0.0 0.074 13.1 0.0 2.0 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain DUF3860 PF12976.7 OEU13223.1 - 0.4 10.7 3.3 2.2 8.4 0.2 2.6 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) zf-UBP PF02148.19 OEU13224.1 - 1.4e-18 66.9 5.3 3.3e-18 65.8 5.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Sec34 PF04136.15 OEU13224.1 - 0.011 15.6 3.0 0.011 15.6 3.0 1.9 2 1 0 2 2 2 0 Sec34-like family zf-UBP_var PF17807.1 OEU13224.1 - 0.028 14.2 1.3 0.052 13.3 1.3 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger NitrOD1 PF18549.1 OEU13224.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 MbeD_MobD PF04899.12 OEU13224.1 - 0.21 11.7 6.9 0.26 11.4 2.8 2.3 1 1 1 2 2 2 0 MbeD/MobD like AAA-ATPase_like PF09820.9 OEU13224.1 - 0.27 10.6 0.1 0.27 10.6 0.1 2.1 1 1 1 2 2 2 0 Predicted AAA-ATPase DUF4391 PF14335.6 OEU13224.1 - 0.3 10.8 10.2 1.5 8.5 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4391) AAA_11 PF13086.6 OEU13224.1 - 0.75 9.5 11.2 3.8 7.2 11.2 1.9 1 1 0 1 1 1 0 AAA domain zinc-ribbons_6 PF07191.12 OEU13224.1 - 0.84 9.7 5.7 1.5 8.8 5.7 1.4 1 0 0 1 1 1 0 zinc-ribbons Golgin_A5 PF09787.9 OEU13224.1 - 1.1 8.7 19.4 0.61 9.5 15.4 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 CCDC-167 PF15188.6 OEU13224.1 - 1.8 9.0 13.8 14 6.1 8.4 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 FAM76 PF16046.5 OEU13224.1 - 1.9 7.8 21.4 0.027 13.8 10.3 2.2 2 0 0 2 2 2 0 FAM76 protein UPF0242 PF06785.11 OEU13224.1 - 2.9 8.0 15.8 6.1 6.9 15.7 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ArfGap PF01412.18 OEU13224.1 - 3 8.0 8.4 0.11 12.6 0.8 2.4 3 1 1 4 4 3 0 Putative GTPase activating protein for Arf Spc7 PF08317.11 OEU13224.1 - 3.3 6.5 15.7 5.8 5.7 15.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 OEU13224.1 - 4.7 8.2 15.6 1.9 9.4 2.1 2.9 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2992 PF11208.8 OEU13224.1 - 8.3 6.7 9.5 0.71 10.1 4.5 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2992) Ank_4 PF13637.6 OEU13225.1 - 1.4e-12 47.9 2.9 2.9e-05 24.5 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU13225.1 - 2.5e-11 44.0 0.2 2.8e-08 34.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU13225.1 - 6.8e-11 41.4 0.2 0.0074 16.7 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OEU13225.1 - 2.8e-10 40.2 0.8 7.3e-05 23.0 0.3 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU13225.1 - 7e-08 32.6 3.5 0.0063 16.9 0.3 4.1 4 0 0 4 4 4 3 Ankyrin repeat Mtp PF03821.16 OEU13226.1 - 0.048 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Fea1 PF07692.11 OEU13227.1 - 2.7e-15 56.3 2.5 5.7e-07 28.9 1.4 2.6 2 1 1 3 3 3 2 Low iron-inducible periplasmic protein Redoxin PF08534.10 OEU13228.1 - 5.2e-34 117.1 0.4 8.9e-34 116.3 0.0 1.5 2 0 0 2 2 2 1 Redoxin Glutaredoxin PF00462.24 OEU13228.1 - 4.3e-13 49.3 0.1 1.4e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.21 OEU13228.1 - 5e-13 49.1 0.0 1.3e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family GST_N_3 PF13417.6 OEU13228.1 - 0.00033 21.0 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 OEU13228.1 - 0.035 14.5 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) mit_SMPDase PF14724.6 OEU13230.1 - 0.076 11.0 0.0 0.094 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase eIF-1a PF01176.19 OEU13231.1 - 3.4e-21 74.8 0.0 5.9e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 OEU13231.1 - 0.04 13.7 0.1 0.092 12.5 0.0 1.7 2 0 0 2 2 2 0 RsgA N-terminal domain RsbRD_N PF14361.6 OEU13232.1 - 0.089 13.5 1.6 0.21 12.3 0.3 2.3 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain CIA30 PF08547.12 OEU13233.1 - 3.9e-21 75.7 0.2 6.4e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ATG_C PF09333.11 OEU13234.1 - 8.1e-18 64.6 0.1 1.9e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OEU13234.1 - 0.23 11.2 0.7 4.1 7.1 0.2 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal CDC45 PF02724.14 OEU13235.1 - 0.0016 16.9 13.8 0.0023 16.3 13.8 1.2 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 OEU13235.1 - 0.0028 15.9 23.3 0.0028 15.9 23.3 1.9 2 0 0 2 2 2 1 DNA polymerase phi Nop14 PF04147.12 OEU13235.1 - 0.033 12.4 28.4 0.054 11.7 28.4 1.3 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 OEU13235.1 - 4.7 6.5 27.6 0.07 12.5 18.8 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) ShK PF01549.24 OEU13236.1 - 9.1e-16 58.1 28.8 1.2e-09 38.6 12.6 2.1 2 0 0 2 2 2 2 ShK domain-like DUF2357 PF09823.9 OEU13236.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Paramecium_SA PF01508.16 OEU13236.1 - 3.8 8.0 21.9 7.6 7.0 7.6 2.5 1 1 1 2 2 2 0 Paramecium surface antigen domain CENP-C_C PF11699.8 OEU13237.1 - 0.0056 16.9 0.0 0.0056 16.9 0.0 3.2 4 0 0 4 4 4 1 Mif2/CENP-C like Cupin_2 PF07883.11 OEU13237.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain AraC_binding PF02311.19 OEU13237.1 - 0.24 11.3 0.0 0.41 10.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain zf-CCCH PF00642.24 OEU13238.1 - 2.3e-28 97.5 28.0 1.7e-09 37.3 4.9 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU13238.1 - 1.7e-15 56.5 38.3 3.8e-05 23.6 8.9 3.6 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 OEU13238.1 - 6.1e-14 51.4 32.0 0.00011 22.0 4.4 3.5 3 1 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 OEU13238.1 - 5.7e-06 27.0 19.5 0.01 16.5 1.0 3.4 2 2 1 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 OEU13238.1 - 1.6e-05 25.2 30.6 0.011 16.2 3.7 3.8 3 1 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OEU13238.1 - 0.72 10.1 12.1 1.1 9.6 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger containing family ParA PF10609.9 OEU13239.1 - 6.1e-63 212.5 0.2 7.5e-63 212.3 0.2 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OEU13239.1 - 1.3e-10 41.4 0.1 1.6e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OEU13239.1 - 1.1e-08 35.2 0.0 6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OEU13239.1 - 1.4e-06 27.8 0.2 0.00012 21.4 0.0 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 OEU13239.1 - 3.2e-05 23.4 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 OEU13239.1 - 0.0024 17.4 0.1 0.061 12.8 0.1 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OEU13239.1 - 0.0032 16.9 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 OEU13239.1 - 0.0044 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 OEU13239.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 OEU13239.1 - 0.036 13.4 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein MeaB PF03308.16 OEU13239.1 - 0.062 12.3 0.2 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRF PF01765.19 OEU13240.1 - 8.7e-59 198.1 5.3 8.7e-59 198.1 5.3 1.6 1 1 0 1 1 1 1 Ribosome recycling factor SpoIIIAH PF12685.7 OEU13240.1 - 0.083 12.7 7.2 0.16 11.8 7.2 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein V-ATPase_G PF03179.15 OEU13240.1 - 8.1 7.0 11.7 1.8 9.1 8.3 1.6 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Pex14_N PF04695.13 OEU13241.1 - 0.13 12.9 3.1 0.15 12.7 0.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cyt-b5 PF00173.28 OEU13242.1 - 5.4e-10 39.3 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 OEU13242.1 - 0.00025 20.9 0.0 0.00065 19.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU13242.1 - 0.002 18.0 0.6 0.0041 16.9 0.0 1.8 2 0 0 2 2 2 1 F-box domain Mog1 PF04603.12 OEU13243.1 - 2e-29 102.8 0.1 4.1e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 Ran-interacting Mog1 protein GSDH PF07995.11 OEU13244.1 - 2.4e-40 138.9 0.0 3.5e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Fasciclin PF02469.22 OEU13244.1 - 4.3e-13 49.6 0.0 9.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain PKD PF00801.20 OEU13244.1 - 1.4e-09 37.6 0.0 3.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 PKD domain REJ PF02010.15 OEU13244.1 - 8.4e-06 24.8 0.0 0.00016 20.6 0.0 2.1 1 1 0 1 1 1 1 REJ domain Fer4_13 PF13370.6 OEU13245.1 - 6.4e-10 39.4 2.2 6.4e-10 39.4 2.2 1.9 2 1 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OEU13245.1 - 2e-07 31.7 2.4 1.4e-06 28.9 2.4 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 OEU13245.1 - 0.094 12.9 9.2 0.18 11.9 4.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 OEU13245.1 - 0.1 12.7 1.1 0.1 12.7 1.1 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_10 PF13237.6 OEU13245.1 - 1.1 9.4 11.3 5.4 7.2 4.5 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 OEU13245.1 - 1.6 8.7 11.1 0.23 11.3 1.9 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Adeno_E3 PF06040.11 OEU13246.1 - 0.043 14.0 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 Adenovirus E3 protein YbhQ PF11076.8 OEU13246.1 - 0.23 11.4 1.3 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Glycos_transf_2 PF00535.26 OEU13248.1 - 1.2e-06 28.4 1.6 0.00022 21.1 0.3 3.0 2 0 0 2 2 2 2 Glycosyl transferase family 2 CIA30 PF08547.12 OEU13249.1 - 0.024 14.7 2.9 0.049 13.7 2.9 1.6 1 1 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Mito_carr PF00153.27 OEU13250.1 - 2.3e-38 130.0 0.1 1.8e-15 56.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3730 PF12530.8 OEU13250.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Lyase_1 PF00206.20 OEU13251.1 - 3.3e-88 296.1 0.0 4.4e-88 295.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OEU13251.1 - 4.6e-25 88.2 0.1 1e-24 87.0 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal IQ PF00612.27 OEU13252.1 - 4.8e-15 53.9 27.2 0.012 15.3 0.9 7.7 7 0 0 7 7 7 6 IQ calmodulin-binding motif Hydrolase_4 PF12146.8 OEU13253.1 - 2.9e-40 138.0 0.0 3.7e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU13253.1 - 9.7e-10 39.4 0.0 1.3e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU13253.1 - 9.9e-10 38.5 0.2 1.6e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OEU13253.1 - 9.2e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OEU13253.1 - 0.00051 19.7 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OEU13253.1 - 0.00077 19.0 0.1 0.018 14.5 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 OEU13253.1 - 0.00077 19.1 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 OEU13253.1 - 0.0017 18.5 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 OEU13253.1 - 0.0034 17.2 1.9 0.048 13.4 0.0 3.1 2 1 2 4 4 4 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OEU13253.1 - 0.0081 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein YjeF_N PF03853.15 OEU13253.1 - 0.01 15.7 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus Lipase_3 PF01764.25 OEU13253.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 OEU13253.1 - 0.12 11.0 1.4 2.2 6.9 1.4 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 OEU13253.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase zf-SNAP50_C PF12251.8 OEU13254.1 - 9.5e-21 74.4 0.2 9.5e-21 74.4 0.2 1.6 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal DUF3246 PF11596.8 OEU13254.1 - 1.5 8.2 25.9 3.1 7.2 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3246) DSPc PF00782.20 OEU13256.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RusA PF05866.11 OEU13257.1 - 4.1e-06 27.4 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA PCRF PF03462.18 OEU13258.1 - 5.2e-39 134.1 0.9 7.5e-39 133.6 0.1 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OEU13258.1 - 5.5e-35 119.8 0.5 1.3e-34 118.6 0.5 1.6 1 0 0 1 1 1 1 RF-1 domain DUF2009 PF09418.10 OEU13258.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) PEMT PF04191.13 OEU13259.1 - 3.5e-11 43.5 0.1 4.9e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 OEU13259.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 OEU13259.1 - 0.00054 18.9 0.0 0.0007 18.5 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OEU13259.1 - 0.047 13.2 0.0 0.051 13.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) HA2 PF04408.23 OEU13261.1 - 3e-23 82.2 0.1 6.1e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OEU13261.1 - 8.9e-21 74.1 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HTH_IclR PF09339.10 OEU13261.1 - 0.16 11.8 0.1 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain DEAD PF00270.29 OEU13262.1 - 2e-10 40.7 0.2 3.3e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU13262.1 - 5.2e-08 33.2 0.0 1.5e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OEU13262.1 - 3.7e-06 27.2 0.1 7.8e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU13262.1 - 0.00014 22.3 0.3 0.00028 21.2 0.2 1.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OEU13262.1 - 0.0017 17.7 0.2 0.0084 15.5 0.0 1.9 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 OEU13262.1 - 0.004 16.3 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OEU13262.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 OEU13262.1 - 0.028 12.7 0.0 0.04 12.1 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Flavi_DEAD PF07652.14 OEU13262.1 - 0.037 14.0 0.1 0.08 12.9 0.1 1.6 1 1 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.22 OEU13262.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 OEU13262.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 OEU13262.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OEU13262.1 - 0.14 12.2 0.2 3.5 7.6 0.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC1 PF03109.16 OEU13263.1 - 1.3e-14 54.4 0.0 2.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 OEU13263.1 - 0.0028 17.0 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OEU13263.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 OEU13264.1 - 2.9e-75 253.7 0.0 3.4e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ILEI PF15711.5 OEU13264.1 - 0.0014 19.1 0.0 0.0041 17.6 0.0 1.8 1 0 0 1 1 1 1 Interleukin-like EMT inducer Methyltransf_11 PF08241.12 OEU13265.1 - 1.2e-11 45.1 0.0 2.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU13265.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU13265.1 - 3.1e-08 34.2 0.0 6.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU13265.1 - 1.8e-07 30.7 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OEU13265.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU13265.1 - 0.0043 17.7 0.0 0.0083 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HMG_box PF00505.19 OEU13266.1 - 1.1e-12 48.1 1.7 6.1e-07 29.8 0.2 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU13266.1 - 1.6e-10 41.4 1.0 1.9e-05 25.2 0.1 2.4 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 OEU13266.1 - 0.021 15.4 0.2 0.045 14.3 0.2 1.5 1 0 0 1 1 1 0 YABBY protein DUF4994 PF16385.5 OEU13266.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Trp_leader2 PF08056.11 OEU13267.1 - 0.033 14.2 1.2 0.08 12.9 1.2 1.6 1 0 0 1 1 1 0 Tryptophan operon leader peptide Porin_3 PF01459.22 OEU13268.1 - 1.4e-15 57.5 5.7 2.2e-15 56.9 5.7 1.1 1 0 0 1 1 1 1 Eukaryotic porin Ntox25 PF15530.6 OEU13268.1 - 0.3 11.2 6.1 0.66 10.1 5.2 2.0 1 1 0 1 1 1 0 Bacterial toxin 25 ATG101 PF07855.12 OEU13269.1 - 1.1e-37 129.4 0.0 1.4e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Gcd10p PF04189.13 OEU13271.1 - 4.7e-45 154.0 0.0 5.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family CmcI PF04989.12 OEU13272.1 - 0.13 11.9 0.1 0.51 10.0 0.1 1.9 1 1 0 1 1 1 0 Cephalosporin hydroxylase RabGAP-TBC PF00566.18 OEU13273.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain YabA PF06156.13 OEU13275.1 - 0.69 10.6 6.1 0.77 10.4 0.1 3.2 3 1 0 3 3 3 0 Initiation control protein YabA 12TM_1 PF09847.9 OEU13276.1 - 0.016 14.3 0.3 0.019 14.1 0.3 1.0 1 0 0 1 1 1 0 Membrane protein of 12 TMs DUF1761 PF08570.10 OEU13276.1 - 0.055 13.7 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) NOA36 PF06524.12 OEU13276.1 - 6.3 6.0 7.4 7.8 5.7 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein CRCB PF02537.15 OEU13279.1 - 6.4e-25 87.3 13.7 7.4e-13 48.6 4.5 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPF0016 PF01169.19 OEU13279.1 - 3.8 7.9 5.5 13 6.2 0.1 3.7 5 0 0 5 5 5 0 Uncharacterized protein family UPF0016 LepA_C PF06421.12 OEU13281.1 - 8.1e-38 128.9 2.0 1.3e-37 128.2 2.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 OEU13281.1 - 5e-37 127.3 0.0 8.2e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OEU13281.1 - 4.4e-13 49.1 0.0 9.6e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus PARP PF00644.20 OEU13282.1 - 6.1e-23 81.4 1.2 4.2e-22 78.7 1.2 1.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ald_Xan_dh_C2 PF02738.18 OEU13284.1 - 1.7e-174 581.3 0.4 2.4e-174 580.8 0.4 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OEU13284.1 - 2.9e-32 111.8 0.0 1.1e-31 109.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OEU13284.1 - 2.1e-28 98.2 0.2 4.2e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OEU13284.1 - 4e-28 97.6 0.0 6.2e-27 93.8 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 OEU13284.1 - 2.7e-10 40.6 0.0 6.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 OEU13284.1 - 6.2e-06 26.1 0.1 6.2e-06 26.1 0.1 2.7 4 0 0 4 4 4 1 2Fe-2S iron-sulfur cluster binding domain MCM PF00493.23 OEU13285.1 - 2.3e-76 255.8 0.0 3.3e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 OEU13285.1 - 1.2e-25 89.8 0.9 2.8e-25 88.6 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OEU13285.1 - 1.6e-22 79.7 0.2 3.9e-22 78.4 0.2 1.7 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 OEU13285.1 - 1.5e-09 37.5 1.0 1.9e-07 30.7 0.1 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU13285.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU13285.1 - 0.031 14.6 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 OEU13285.1 - 0.082 12.6 0.0 0.57 9.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 OEU13285.1 - 0.11 12.2 0.2 0.34 10.7 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SIP1 PF04938.12 OEU13286.1 - 3.2e-36 125.1 0.0 5e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FPL PF09758.9 OEU13288.1 - 6.8e-17 61.8 4.3 1e-14 54.8 4.3 2.7 1 1 0 1 1 1 1 Uncharacterised conserved protein PNP_UDP_1 PF01048.20 OEU13289.1 - 6.6e-45 153.2 0.5 8.8e-45 152.8 0.5 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Dishevelled PF02377.15 OEU13290.1 - 0.035 14.6 3.5 0.048 14.1 3.5 1.2 1 0 0 1 1 1 0 Dishevelled specific domain DUF5600 PF18150.1 OEU13291.1 - 1.2e-37 128.8 0.6 2.4e-37 127.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 OEU13291.1 - 5.3e-19 68.1 0.0 3.4e-18 65.5 0.0 2.3 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 OEU13291.1 - 2.4e-15 57.0 0.0 1.8e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EHD_N PF16880.5 OEU13291.1 - 5.2e-11 42.2 2.2 5.2e-11 42.2 2.2 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 OEU13291.1 - 4.9e-10 39.5 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 OEU13291.1 - 0.00024 20.9 0.7 0.077 12.9 0.1 3.6 3 1 1 4 4 4 1 EF-hand domain pair Roc PF08477.13 OEU13291.1 - 0.0016 18.6 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 OEU13291.1 - 0.0091 15.5 0.3 0.028 13.9 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OEU13291.1 - 0.02 15.3 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair FeoB_N PF02421.18 OEU13291.1 - 0.035 13.6 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ABA_GPCR PF12430.8 OEU13292.1 - 2.9e-13 50.0 10.4 2.9e-13 50.0 10.4 2.2 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OEU13292.1 - 2.5e-08 33.9 0.1 2.5e-08 33.9 0.1 2.6 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal MacB_PCD PF12704.7 OEU13292.1 - 0.34 11.2 4.7 0.78 10.1 4.7 1.7 1 1 0 1 1 1 0 MacB-like periplasmic core domain Dus PF01207.17 OEU13294.1 - 8.2e-47 159.8 0.0 1.4e-45 155.8 0.0 2.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) RRM_1 PF00076.22 OEU13295.1 - 2e-09 37.1 0.0 2.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OEU13295.1 - 0.073 13.1 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 DbpA RNA binding domain Aim21 PF11489.8 OEU13297.1 - 0.012 14.6 0.8 0.015 14.2 0.8 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 TauD PF02668.16 OEU13298.1 - 6.9e-27 94.9 0.1 1.9e-26 93.4 0.0 1.8 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OEU13298.1 - 0.033 13.3 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 CsiD FBPase PF00316.20 OEU13300.1 - 1e-60 204.4 0.3 5.1e-60 202.2 0.3 1.8 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain PDZ_6 PF17820.1 OEU13301.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU13301.1 - 0.04 14.3 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PG_binding_4 PF12229.8 OEU13301.1 - 8.7 6.7 8.9 0.23 11.7 0.8 2.5 3 0 0 3 3 3 0 Putative peptidoglycan binding domain PseudoU_synth_1 PF01416.20 OEU13302.1 - 1.7e-24 86.3 0.0 4.1e-24 85.1 0.0 1.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase Nuc_sug_transp PF04142.15 OEU13303.1 - 5.9e-107 357.5 20.1 6.6e-107 357.3 20.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OEU13303.1 - 1.3e-08 34.4 18.6 5.9e-08 32.3 18.6 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU13303.1 - 5.7e-08 33.0 24.9 2.3e-06 27.8 1.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OEU13303.1 - 3.2e-06 26.6 23.3 9.3e-06 25.1 23.3 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 OEU13303.1 - 0.00016 20.8 5.0 0.00016 20.8 5.0 2.1 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 OEU13303.1 - 0.031 13.8 11.3 0.1 12.2 11.0 2.1 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter Multi_Drug_Res PF00893.19 OEU13303.1 - 0.2 12.3 0.2 0.2 12.3 0.2 3.0 3 1 0 3 3 3 0 Small Multidrug Resistance protein DUF1129 PF06570.11 OEU13303.1 - 0.42 10.1 6.7 6.4 6.2 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) HSF_DNA-bind PF00447.17 OEU13304.1 - 1.5e-15 57.5 1.6 1.8e-15 57.3 0.1 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Roughex PF06020.11 OEU13304.1 - 8.3 5.4 11.4 4.4 6.3 3.5 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Pkinase PF00069.25 OEU13306.1 - 4.8e-15 55.6 0.0 5.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13306.1 - 9e-11 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_3 PF13302.7 OEU13307.1 - 3.7e-14 53.6 0.0 4.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU13307.1 - 3.4e-08 33.7 0.0 4.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU13307.1 - 0.056 13.9 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SET PF00856.28 OEU13308.1 - 5e-19 69.3 0.1 6.2e-18 65.7 0.1 2.0 1 1 0 1 1 1 1 SET domain SmpB PF01668.18 OEU13309.1 - 4.1e-50 169.4 2.3 4.7e-50 169.2 2.3 1.0 1 0 0 1 1 1 1 SmpB protein DUF4576 PF15144.6 OEU13310.1 - 0.097 12.6 0.2 0.47 10.4 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) PseudoU_synth_2 PF00849.22 OEU13311.1 - 1.1e-15 58.1 0.0 2.5e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Methyltransf_11 PF08241.12 OEU13312.1 - 9.3e-17 61.5 0.1 2.3e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU13312.1 - 2.4e-14 53.5 0.0 4.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU13312.1 - 8.7e-14 52.0 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU13312.1 - 1.3e-11 44.3 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU13312.1 - 4.3e-11 43.4 0.3 1.4e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU13312.1 - 1.5e-09 37.8 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OEU13312.1 - 0.00039 19.1 0.0 0.0007 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 OEU13312.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase PseudoU_synth_2 PF00849.22 OEU13313.1 - 3.8e-18 66.1 0.0 7.2e-18 65.2 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase Kinesin PF00225.23 OEU13314.1 - 2.2e-100 335.8 5.9 2.7e-100 335.6 5.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU13314.1 - 1e-23 83.9 0.4 2.5e-23 82.6 0.1 1.8 2 0 0 2 2 2 1 Microtubule binding NUC153 PF08159.12 OEU13317.1 - 4.6e-06 26.3 6.2 0.00012 21.9 0.3 3.3 3 0 0 3 3 3 2 NUC153 domain AAA_12 PF13087.6 OEU13318.1 - 1.4e-51 175.0 0.0 1.7e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OEU13318.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OEU13318.1 - 0.0045 16.8 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OEU13318.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain GTP1_OBG PF01018.22 OEU13319.1 - 6e-35 120.1 1.5 6e-35 120.1 1.5 1.5 2 0 0 2 2 2 1 GTP1/OBG MMR_HSR1 PF01926.23 OEU13319.1 - 1.1e-18 67.4 0.0 1.8e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU13319.1 - 1e-06 28.4 0.0 2.3e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 OEU13319.1 - 0.0016 18.0 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OEU13319.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MeaB PF03308.16 OEU13319.1 - 0.035 13.1 0.1 7.2 5.5 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ADAM_spacer1 PF05986.14 OEU13319.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Hydantoinase_B PF02538.14 OEU13319.1 - 0.25 9.7 3.0 0.37 9.1 3.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase AstE_AspA PF04952.14 OEU13320.1 - 4.6e-14 52.2 0.0 3.5e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Nsp1_C PF05064.13 OEU13320.1 - 0.35 10.7 1.6 0.72 9.7 1.6 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Sugar_tr PF00083.24 OEU13321.1 - 2.9e-40 138.5 17.9 3.9e-40 138.1 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU13321.1 - 3.1e-26 92.1 16.4 4.4e-26 91.6 16.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OEU13321.1 - 0.00093 17.7 4.5 0.00093 17.7 4.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_35 PF01301.19 OEU13322.1 - 4e-52 177.8 3.2 4.3e-50 171.1 3.2 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OEU13322.1 - 7.6e-05 23.3 4.5 0.02 15.5 0.0 3.8 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain Methyltransf_15 PF09445.10 OEU13323.1 - 7.9e-23 80.8 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 OEU13323.1 - 0.0031 17.2 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 OEU13323.1 - 0.021 14.5 0.0 0.27 10.9 0.0 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 OEU13323.1 - 0.064 12.5 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 OEU13323.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 DNA methylase LCM PF04072.14 OEU13325.1 - 1.1e-21 77.6 0.1 1.5e-11 44.6 0.0 2.4 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase UFD1 PF03152.14 OEU13326.1 - 1.9e-22 79.6 0.2 3e-12 46.3 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 OEU13326.1 - 7.8e-08 32.4 0.1 2.2e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 UBX domain SRP54 PF00448.22 OEU13328.1 - 3.3e-69 232.5 0.2 6.2e-69 231.6 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OEU13328.1 - 2.1e-21 76.4 8.7 4.3e-21 75.4 4.9 2.8 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 OEU13328.1 - 1.5e-16 60.4 2.4 1.6e-15 57.0 0.2 2.7 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 OEU13328.1 - 1.9e-06 27.3 0.1 3.5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OEU13328.1 - 0.0094 16.4 0.4 0.021 15.2 0.2 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OEU13328.1 - 0.015 14.9 0.8 0.059 12.9 0.7 2.1 1 1 0 1 1 1 0 AAA domain DUF5498 PF17602.2 OEU13328.1 - 0.042 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5498) AAA_24 PF13479.6 OEU13328.1 - 0.044 13.5 0.4 0.29 10.8 0.4 2.3 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 OEU13328.1 - 0.047 13.0 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein MMR_HSR1 PF01926.23 OEU13328.1 - 0.25 11.5 2.3 0.93 9.6 0.1 2.9 4 0 0 4 4 4 0 50S ribosome-binding GTPase NUDIX PF00293.28 OEU13329.1 - 7.4e-12 45.4 0.1 1.3e-11 44.6 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain DUF5340 PF17275.2 OEU13329.1 - 0.13 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5340) ETRAMP PF09716.10 OEU13329.1 - 0.33 11.0 2.4 1.2 9.2 2.4 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PI3_PI4_kinase PF00454.27 OEU13330.1 - 8.6e-29 101.1 0.0 9.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HTH_38 PF13936.6 OEU13330.1 - 0.031 14.0 0.0 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Serinc PF03348.15 OEU13331.1 - 2e-79 267.6 3.4 2.3e-79 267.3 3.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) SbcCD_C PF13558.6 OEU13331.1 - 0.075 13.3 0.1 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF2070 PF09843.9 OEU13331.1 - 2.3 6.4 16.8 0.25 9.6 4.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Tom22 PF04281.13 OEU13333.1 - 0.0045 16.8 0.1 0.0056 16.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DHFR_1 PF00186.19 OEU13334.1 - 1.6e-10 41.0 0.6 8.9e-09 35.2 0.1 2.9 2 1 0 2 2 2 1 Dihydrofolate reductase HA PF03457.14 OEU13336.1 - 1e-72 240.4 16.1 2.8e-16 59.6 0.1 6.3 6 0 0 6 6 6 6 Helicase associated domain Gag_p10 PF02337.17 OEU13336.1 - 0.01 15.8 1.3 3.5 7.6 0.1 4.1 4 0 0 4 4 4 0 Retroviral GAG p10 protein RRN3 PF05327.11 OEU13337.1 - 1.8e-77 261.2 0.5 9.7e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.11 OEU13337.1 - 0.037 14.1 0.0 0.16 12.0 0.0 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) CdiA_C PF18451.1 OEU13337.1 - 0.063 13.5 0.4 0.27 11.5 0.4 2.1 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain Kelch_2 PF07646.15 OEU13337.1 - 0.16 12.0 0.0 0.51 10.4 0.0 1.9 1 0 0 1 1 1 0 Kelch motif FKBP_C PF00254.28 OEU13338.1 - 6.1e-17 61.7 0.0 7.8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AIRC PF00731.20 OEU13339.1 - 7.2e-14 51.6 3.6 7.2e-14 51.6 3.6 1.6 2 0 0 2 2 2 1 AIR carboxylase GP70 PF17429.2 OEU13339.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Gene product 70 DnaJ PF00226.31 OEU13341.1 - 0.0089 16.1 1.2 0.06 13.5 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain CRAL_TRIO_2 PF13716.6 OEU13341.1 - 0.11 12.6 1.7 0.11 12.6 0.6 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain DUF4407 PF14362.6 OEU13341.1 - 0.74 9.1 3.2 0.88 8.9 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L41 PF05162.13 OEU13342.1 - 5.5e-07 29.5 35.6 8.2e-07 29.0 35.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L41 ubiquitin PF00240.23 OEU13342.1 - 0.11 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family NUDIX PF00293.28 OEU13343.1 - 1.9e-18 66.7 0.0 2.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 OEU13343.1 - 2.4e-11 43.4 0.4 6e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 Nudix hydrolase domain DUF3738 PF12543.8 OEU13343.1 - 0.22 11.6 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) DUF1995 PF09353.10 OEU13344.1 - 6.9e-10 39.3 0.0 7.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) SF3b1 PF08920.10 OEU13347.1 - 9.1e-31 106.8 11.3 1.2e-28 99.9 4.3 2.6 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 OEU13347.1 - 2.9e-08 34.0 9.1 0.063 13.7 0.1 6.5 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.22 OEU13347.1 - 1.3e-05 25.0 15.7 11 6.6 0.0 9.8 14 0 0 14 14 10 2 HEAT repeat HEAT_EZ PF13513.6 OEU13347.1 - 0.00016 22.1 6.0 0.6 10.7 0.0 7.3 8 1 1 9 9 8 1 HEAT-like repeat Adaptin_N PF01602.20 OEU13347.1 - 0.00049 18.8 0.1 1.3 7.4 0.0 3.0 2 2 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OEU13347.1 - 0.0007 20.1 1.8 4.7 7.9 0.0 4.7 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region CTD PF12815.7 OEU13347.1 - 0.00094 19.7 5.5 0.0036 17.8 5.6 1.9 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 MMS22L_C PF14911.6 OEU13347.1 - 0.0047 16.1 0.0 0.039 13.1 0.0 2.4 2 0 0 2 2 2 1 S-phase genomic integrity recombination mediator, C-terminal NUC173 PF08161.12 OEU13347.1 - 0.006 16.3 0.2 1 9.0 0.0 4.4 5 1 1 6 6 6 1 NUC173 domain MMS19_C PF12460.8 OEU13347.1 - 0.0063 15.7 0.0 0.61 9.1 0.0 3.0 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OEU13347.1 - 0.05 13.2 0.2 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal DRIM PF07539.12 OEU13347.1 - 0.089 11.1 0.1 4.8 5.4 0.0 3.2 3 1 1 4 4 4 0 Down-regulated in metastasis Paz_1 PF18349.1 OEU13347.1 - 0.15 12.0 0.1 3.7 7.6 0.1 2.8 2 0 0 2 2 2 0 PAZ domain Lipase_3 PF01764.25 OEU13349.1 - 6.6e-24 84.4 0.0 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 OEU13349.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OEU13349.1 - 0.035 13.4 0.1 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU13349.1 - 0.049 14.2 0.0 0.076 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OEU13349.1 - 0.059 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 OEU13349.1 - 0.12 11.9 0.3 1 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF1351 PF07083.11 OEU13350.1 - 0.0023 17.8 0.3 0.0062 16.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1351) Fis1_TPR_C PF14853.6 OEU13351.1 - 1.2e-06 28.4 0.2 5.4e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OEU13351.1 - 1.2e-05 24.8 0.4 2.5e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.6 OEU13351.1 - 0.0032 18.0 0.5 0.0081 16.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU13351.1 - 0.018 15.7 0.2 0.037 14.7 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TMEM61 PF15105.6 OEU13351.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 TMEM61 protein family TPR_3 PF07720.12 OEU13351.1 - 0.12 12.4 1.0 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Zip PF02535.22 OEU13352.1 - 6.9e-10 38.7 19.1 3.9e-07 29.6 14.1 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter FA_desaturase PF00487.24 OEU13352.1 - 0.43 10.4 3.1 0.21 11.4 0.2 1.9 2 0 0 2 2 2 0 Fatty acid desaturase Fer2 PF00111.27 OEU13353.1 - 1.6e-07 31.2 2.3 2.8e-07 30.4 2.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 OEU13353.1 - 2.4e-05 24.3 1.5 2.4e-05 24.3 1.5 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 OEU13353.1 - 0.00036 20.5 2.7 0.00082 19.4 2.7 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mak10 PF04112.13 OEU13354.1 - 1.1e-19 70.6 6.5 1e-18 67.5 6.5 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Myb_DNA-binding PF00249.31 OEU13355.1 - 5.6e-21 74.5 0.4 2.2e-11 43.7 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU13355.1 - 1.1e-16 60.8 0.4 3.1e-12 46.5 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU13355.1 - 0.0009 19.1 0.1 0.0016 18.3 0.0 1.4 1 1 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OEU13355.1 - 0.1 12.8 0.1 0.66 10.2 0.1 2.0 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 PSI PF01437.25 OEU13356.1 - 0.0002 21.8 39.6 0.0043 17.6 14.8 3.2 2 1 0 2 2 2 2 Plexin repeat DUF3568 PF12092.8 OEU13356.1 - 0.46 10.6 7.6 0.049 13.7 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) MAP65_ASE1 PF03999.12 OEU13356.1 - 0.75 8.4 5.3 0.9 8.2 5.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PSI_integrin PF17205.3 OEU13356.1 - 4.6 7.1 40.0 0.48 10.2 13.0 3.1 2 2 0 2 2 2 0 Integrin plexin domain ABC_membrane PF00664.23 OEU13357.1 - 3.6e-82 276.1 21.8 1.4e-42 146.2 1.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU13357.1 - 5.5e-68 227.8 0.4 1.1e-33 116.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_29 PF13555.6 OEU13357.1 - 2.3e-08 33.6 0.1 0.0059 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU13357.1 - 1.1e-07 32.2 0.8 0.0089 16.3 0.0 3.4 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OEU13357.1 - 5.2e-07 29.7 0.0 0.053 13.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase SMC_N PF02463.19 OEU13357.1 - 7e-07 28.9 0.0 0.00048 19.6 0.5 3.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU13357.1 - 1.9e-06 28.4 0.1 0.0099 16.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OEU13357.1 - 2.1e-06 27.6 0.2 0.0051 16.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 OEU13357.1 - 2.2e-06 26.7 0.4 0.0082 15.0 0.3 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 OEU13357.1 - 1.9e-05 24.6 4.9 0.047 13.4 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 OEU13357.1 - 2.8e-05 24.7 0.9 0.63 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 OEU13357.1 - 7.2e-05 22.8 0.5 3.9 7.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OEU13357.1 - 8.4e-05 22.6 0.0 0.17 11.8 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA PF00004.29 OEU13357.1 - 0.00016 22.1 2.9 0.43 11.0 0.1 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OEU13357.1 - 0.0003 21.3 0.0 0.43 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OEU13357.1 - 0.00032 20.6 0.1 1.3 8.7 0.0 3.7 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 OEU13357.1 - 0.0012 19.2 0.8 3.9 7.9 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_7 PF12775.7 OEU13357.1 - 0.0016 18.0 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OEU13357.1 - 0.0049 16.6 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 OEU13357.1 - 0.007 16.1 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase PRK PF00485.18 OEU13357.1 - 0.007 16.1 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 OEU13357.1 - 0.017 14.7 0.0 4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OEU13357.1 - 0.026 13.7 0.3 1.4 8.0 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit APS_kinase PF01583.20 OEU13357.1 - 0.031 14.2 0.0 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 OEU13357.1 - 0.043 14.2 0.3 6.1 7.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OEU13357.1 - 0.044 14.0 1.0 8.9 6.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 OEU13357.1 - 0.051 13.8 2.2 6.4 7.1 0.2 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 OEU13357.1 - 0.053 13.7 0.0 17 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OEU13357.1 - 0.058 13.1 1.2 3.7 7.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OEU13357.1 - 0.066 13.1 0.1 7.1 6.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 OEU13357.1 - 0.081 12.6 0.0 7.5 6.2 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 OEU13357.1 - 0.094 12.1 0.0 17 4.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 OEU13357.1 - 0.12 12.5 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2852 PF11014.8 OEU13357.1 - 9.1 6.5 6.3 4.2 7.5 0.2 3.0 4 0 0 4 4 2 0 Protein of unknown function (DUF2852) Glyco_transf_34 PF05637.12 OEU13358.1 - 4e-10 39.8 0.1 7.2e-09 35.7 0.1 2.3 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family WBP-1 PF11669.8 OEU13359.1 - 0.079 13.6 0.2 0.19 12.4 0.2 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 ThiF PF00899.21 OEU13360.1 - 8.2e-29 100.7 0.1 9.8e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 ThiF family Nitro_FeMo-Co PF02579.17 OEU13360.1 - 0.05 13.9 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor ELFV_dehydrog PF00208.21 OEU13360.1 - 0.069 12.9 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 OEU13360.1 - 0.077 13.3 0.7 0.47 10.7 0.7 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 OEU13360.1 - 0.3 10.6 2.4 0.49 9.9 2.2 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_C1 PF00112.23 OEU13361.1 - 4.7e-46 157.6 10.8 7.6e-46 156.9 10.8 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OEU13361.1 - 3.1e-08 33.9 0.7 5.3e-08 33.2 0.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) GDP_Man_Dehyd PF16363.5 OEU13362.1 - 1.1e-56 192.7 0.0 1.3e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU13362.1 - 1.9e-47 161.8 0.0 2.5e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU13362.1 - 6.2e-14 51.7 0.1 8.4e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU13362.1 - 5.9e-12 45.3 0.0 2.5e-10 40.0 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OEU13362.1 - 1.6e-08 34.0 0.0 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OEU13362.1 - 7.5e-08 31.8 0.0 1.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 OEU13362.1 - 4.6e-06 26.7 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OEU13362.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 OEU13362.1 - 0.0089 15.6 0.4 0.016 14.8 0.4 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 OEU13362.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Atx10homo_assoc PF09759.9 OEU13363.1 - 1.5e-20 73.0 2.5 2.2e-17 62.9 0.1 3.3 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain DUF2749 PF10907.8 OEU13365.1 - 0.23 11.6 2.1 0.32 11.2 0.6 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2749) Ank_2 PF12796.7 OEU13366.1 - 0.028 15.0 0.0 0.06 13.9 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Nucleocapsid-N PF11030.8 OEU13366.1 - 0.04 13.9 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N NMD3 PF04981.13 OEU13367.1 - 6.7e-11 42.1 0.1 8.8e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 NMD3 family FAM180 PF15173.6 OEU13367.1 - 0.072 13.1 0.0 0.76 9.8 0.0 1.9 2 0 0 2 2 2 0 FAM180 family CRA PF06589.11 OEU13368.1 - 0.99 9.5 16.6 2.1 8.5 8.0 2.2 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Nop14 PF04147.12 OEU13368.1 - 3.5 5.7 22.9 4 5.5 22.9 1.0 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.18 OEU13369.1 - 9.9e-57 192.5 2.3 1.7e-56 191.7 2.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein COX6C PF02937.15 OEU13369.1 - 0.2 11.8 0.2 2.7 8.2 0.0 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc YIF1 PF03878.15 OEU13370.1 - 2.9e-52 177.6 2.9 2.9e-52 177.6 2.9 1.5 2 0 0 2 2 2 1 YIF1 Yip1 PF04893.17 OEU13370.1 - 7.6e-07 29.0 1.0 7.6e-07 29.0 1.0 1.8 2 0 0 2 2 2 1 Yip1 domain TFIIA PF03153.13 OEU13370.1 - 0.085 12.8 20.0 0.11 12.5 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 OEU13370.1 - 0.19 12.4 17.4 0.37 11.4 17.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L18 PF17135.4 OEU13371.1 - 5.7e-79 263.9 2.0 6.3e-79 263.7 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OEU13371.1 - 0.00055 20.6 0.1 0.0014 19.3 0.1 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nudc_N PF14050.6 OEU13371.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. DUF1737 PF08410.10 OEU13371.1 - 0.058 13.2 0.3 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) HiaBD2 PF15403.6 OEU13373.1 - 0.019 15.4 3.7 15 6.0 0.0 4.6 5 0 0 5 5 5 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) CaM_bdg_C0 PF10562.9 OEU13373.1 - 0.13 12.3 53.0 0.21 11.6 3.6 6.9 6 0 0 6 6 6 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Tower PF09121.10 OEU13373.1 - 0.17 12.1 25.4 3.6 7.8 1.5 5.2 4 0 0 4 4 4 0 Tower Rad51 PF08423.11 OEU13374.1 - 1.1e-25 90.4 0.7 2.7e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 OEU13374.1 - 6.5e-10 38.8 0.0 8.7e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 OEU13374.1 - 7.8e-10 38.7 0.1 2.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 OEU13374.1 - 1.3e-05 25.2 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RecA PF00154.21 OEU13374.1 - 5e-05 22.9 0.0 0.00094 18.7 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 OEU13374.1 - 8.2e-05 22.1 0.0 0.28 10.5 0.0 2.4 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain ABC_tran PF00005.27 OEU13374.1 - 0.0075 16.8 0.6 0.0075 16.8 0.6 2.2 3 1 0 3 3 3 1 ABC transporter PhoH PF02562.16 OEU13374.1 - 0.098 12.1 0.4 0.18 11.2 0.4 1.3 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 OEU13374.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OEU13374.1 - 0.15 12.2 1.5 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain COPI_assoc PF08507.10 OEU13375.1 - 2.6 8.1 16.2 0.31 11.1 11.2 2.0 2 1 0 2 2 2 0 COPI associated protein adh_short PF00106.25 OEU13376.1 - 1.5e-25 89.8 0.0 5.4e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU13376.1 - 4.7e-20 72.1 0.0 6.7e-11 42.2 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU13376.1 - 5.9e-07 29.6 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OEU13376.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding CN_hydrolase PF00795.22 OEU13377.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase CSD PF00313.22 OEU13378.1 - 1.9e-17 62.8 0.5 2.7e-17 62.4 0.5 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU13378.1 - 0.023 14.4 0.1 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Secretin_N_2 PF07655.13 OEU13379.1 - 0.33 11.5 0.2 0.33 11.5 0.2 2.6 2 1 0 2 2 2 0 Secretin N-terminal domain Lipase_GDSL_2 PF13472.6 OEU13380.1 - 3.2e-06 27.6 0.0 0.00024 21.5 0.0 2.4 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Peptidase_M16_M PF16187.5 OEU13382.1 - 1.5e-75 254.1 0.1 2.4e-75 253.4 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OEU13382.1 - 8.4e-30 103.7 0.3 2.4e-29 102.2 0.3 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU13382.1 - 3.2e-22 79.4 0.1 3.2e-13 50.1 0.0 3.3 3 1 0 3 3 3 2 Peptidase M16 inactive domain YycC PF14174.6 OEU13383.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein DUF1744 PF08490.12 OEU13384.1 - 1.2e-66 225.0 0.0 1.2e-64 218.4 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OEU13384.1 - 6.5e-64 216.2 0.0 1.4e-63 215.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OEU13384.1 - 1.3e-11 43.9 0.2 3.7e-10 39.1 0.2 3.3 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OEU13384.1 - 8e-07 28.9 0.2 6.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OEU13384.1 - 7.3e-06 26.1 0.0 0.00011 22.3 0.0 2.6 2 0 0 2 2 2 1 RNase_H superfamily Mannitol_dh_C PF08125.13 OEU13384.1 - 0.09 12.2 1.7 0.094 12.2 0.0 1.8 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain AMP-binding PF00501.28 OEU13385.1 - 9.7e-25 87.0 0.0 1.7e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OEU13385.1 - 7.2e-07 29.5 0.5 1.5e-06 28.4 0.5 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PQQ_3 PF13570.6 OEU13385.1 - 2.5e-05 24.6 4.4 0.17 12.5 0.1 4.8 4 1 1 5 5 5 2 PQQ-like domain PQQ_2 PF13360.6 OEU13385.1 - 0.0008 19.1 0.0 0.16 11.5 0.0 2.7 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OEU13385.1 - 0.32 11.0 2.0 28 4.9 0.0 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat E1-E2_ATPase PF00122.20 OEU13386.1 - 5.8e-16 58.5 3.1 2.3e-13 50.1 0.0 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 OEU13386.1 - 6.1e-13 49.5 0.4 3.8e-06 27.3 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU13386.1 - 0.00028 20.9 0.0 0.00084 19.4 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) SUFU PF05076.13 OEU13386.1 - 0.087 12.8 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) HEAT_EZ PF13513.6 OEU13387.1 - 1.8e-26 92.2 19.8 5.6e-11 42.7 0.1 11.4 9 2 2 11 11 11 2 HEAT-like repeat HEAT PF02985.22 OEU13387.1 - 1.1e-20 71.9 28.7 4.9e-08 32.6 0.1 11.1 13 0 0 13 13 11 5 HEAT repeat HEAT_2 PF13646.6 OEU13387.1 - 3.8e-16 59.3 17.3 1.7e-05 25.1 0.0 10.0 8 3 3 11 11 10 6 HEAT repeats Vac14_Fab1_bd PF12755.7 OEU13387.1 - 1.3e-15 57.8 0.0 1.5e-08 35.1 0.0 6.7 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OEU13387.1 - 8e-09 35.7 0.7 1.1e-05 25.6 0.1 4.6 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OEU13387.1 - 7e-08 32.3 0.0 0.12 11.9 0.0 5.8 5 1 0 5 5 5 1 CLASP N terminal IBN_N PF03810.19 OEU13387.1 - 2.4e-07 30.5 0.0 1.1e-05 25.2 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Tti2 PF10521.9 OEU13387.1 - 4e-07 29.8 0.0 0.0051 16.4 0.0 4.1 3 1 1 4 4 4 2 Tti2 family Adaptin_N PF01602.20 OEU13387.1 - 8.9e-07 27.8 1.0 0.00031 19.5 0.1 2.9 3 0 0 3 3 3 2 Adaptin N terminal region UME PF08064.13 OEU13387.1 - 2.9e-06 27.1 0.8 1.7 8.6 0.0 5.8 5 1 0 6 6 5 1 UME (NUC010) domain RIX1 PF08167.12 OEU13387.1 - 4e-05 23.4 0.1 0.064 13.0 0.0 4.8 4 1 0 5 5 5 1 rRNA processing/ribosome biogenesis V-ATPase_H_N PF03224.14 OEU13387.1 - 0.0013 18.1 0.5 2.1 7.6 0.2 3.2 2 1 1 4 4 4 2 V-ATPase subunit H TIP120 PF08623.10 OEU13387.1 - 0.0017 18.1 0.2 0.62 9.8 0.0 3.7 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) Xpo1 PF08389.12 OEU13387.1 - 0.0019 18.2 0.9 1.9 8.6 0.2 4.4 3 1 0 3 3 3 1 Exportin 1-like protein Importin_rep_4 PF18808.1 OEU13387.1 - 0.013 15.7 4.0 0.036 14.3 0.1 3.4 3 0 0 3 3 3 0 Importin repeat RTP1_C1 PF10363.9 OEU13387.1 - 0.018 15.2 0.0 1.6 8.9 0.0 3.7 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 OEU13387.1 - 0.042 13.9 15.8 1.2 9.3 0.1 8.3 11 0 0 11 11 10 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 OEU13387.1 - 0.056 13.8 0.4 1.9 8.9 0.2 3.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 NUC173 PF08161.12 OEU13387.1 - 0.23 11.1 0.7 35 4.0 0.1 4.2 4 1 0 4 4 4 0 NUC173 domain HEAT_PBS PF03130.16 OEU13387.1 - 0.23 12.2 2.4 1.2e+02 3.8 0.0 5.2 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 OEU13387.1 - 0.23 11.6 0.5 63 3.7 0.0 4.2 5 0 0 5 5 5 0 V-ATPase subunit H DUF3730 PF12530.8 OEU13387.1 - 2.1 7.9 10.5 8.6 5.9 5.8 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3730) FrhB_FdhB_C PF04432.13 OEU13388.1 - 1.2e-28 99.9 0.1 1.9e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 OEU13388.1 - 4.2e-15 55.7 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term SR-25 PF10500.9 OEU13388.1 - 0.067 12.8 4.5 0.13 11.9 4.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 OEU13390.1 - 8.5e-15 53.6 10.3 0.1 12.9 0.0 8.7 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 OEU13390.1 - 3.5e-08 33.7 9.9 0.013 15.9 0.4 7.0 6 1 2 8 8 8 1 HEAT repeats CLASP_N PF12348.8 OEU13390.1 - 1e-05 25.3 0.1 0.051 13.1 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 OEU13390.1 - 0.0013 18.8 2.3 1.8 8.6 0.0 4.6 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OEU13390.1 - 0.058 13.9 3.0 4.2 8.0 0.1 4.3 3 1 1 4 4 4 0 HEAT-like repeat DUF591 PF04569.14 OEU13391.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2951 PF11166.8 OEU13392.1 - 2.7 8.3 7.9 1.5 9.1 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) PilJ PF13675.6 OEU13392.1 - 8.5 6.4 8.0 2.3 8.2 0.1 2.7 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cytadhesin_P30 PF07271.11 OEU13393.1 - 2.3 7.7 4.4 2.8 7.4 4.4 1.0 1 0 0 1 1 1 0 Cytadhesin P30/P32 CPBP PF02517.16 OEU13394.1 - 3.5e-12 46.5 0.8 8e-12 45.4 0.8 1.6 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Longin_2 PF18639.1 OEU13394.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Yeast longin domain Hexapep PF00132.24 OEU13395.1 - 1.9e-12 46.4 6.9 6.8e-07 28.8 0.2 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 OEU13395.1 - 1.6e-07 31.7 0.1 2.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 OEU13395.1 - 0.00015 21.4 11.3 0.00078 19.1 1.1 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Utp14 PF04615.13 OEU13396.1 - 0.0087 14.7 15.9 0.013 14.1 15.9 1.3 1 0 0 1 1 1 1 Utp14 protein SDA1 PF05285.12 OEU13396.1 - 0.012 15.0 31.7 0.017 14.6 31.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OEU13396.1 - 4.3 5.5 24.4 7.9 4.6 24.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Myosin_head PF00063.21 OEU13397.1 - 2.1e-208 693.8 0.1 3e-208 693.3 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 OEU13397.1 - 0.0043 17.5 0.1 0.016 15.6 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU13397.1 - 0.0067 16.7 0.3 0.072 13.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OEU13397.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3987 PF13148.6 OEU13397.1 - 0.057 12.4 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_10 PF12846.7 OEU13397.1 - 0.067 12.1 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain Peptidase_M41 PF01434.18 OEU13398.1 - 1.7e-60 204.1 0.1 2.7e-60 203.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OEU13398.1 - 2.3e-43 147.8 0.0 8.7e-43 145.9 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU13398.1 - 7.2e-14 51.3 0.2 2.5e-13 49.6 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OEU13398.1 - 1.9e-06 28.0 0.1 0.0026 17.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU13398.1 - 4.9e-05 23.6 0.0 0.027 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU13398.1 - 0.0011 19.2 0.0 0.0071 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OEU13398.1 - 0.0017 17.6 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 OEU13398.1 - 0.0028 17.4 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 OEU13398.1 - 0.0063 16.9 0.1 0.021 15.2 0.1 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_18 PF13238.6 OEU13398.1 - 0.01 16.4 1.2 0.17 12.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 OEU13398.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 OEU13398.1 - 0.014 15.6 0.0 0.071 13.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OEU13398.1 - 0.02 15.3 1.6 0.25 11.7 0.2 2.9 2 1 1 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 OEU13398.1 - 0.044 13.2 0.2 0.095 12.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OEU13398.1 - 0.083 13.3 1.2 0.14 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain THEG PF14912.6 OEU13398.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Testicular haploid expressed repeat AAA_28 PF13521.6 OEU13398.1 - 0.13 12.5 0.7 0.75 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OEU13398.1 - 0.13 12.2 0.1 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OEU13398.1 - 0.14 11.4 0.4 9.2 5.5 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin GlutR_dimer PF00745.20 OEU13398.1 - 4.7 7.7 6.0 6.3 7.3 2.3 2.3 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Gp_dh_C PF02800.20 OEU13399.1 - 1.9e-57 193.3 0.0 3.7e-57 192.3 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU13399.1 - 3.6e-31 107.5 0.1 8.6e-31 106.3 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Runt PF00853.19 OEU13399.1 - 0.1 12.1 0.3 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Runt domain Cys_Met_Meta_PP PF01053.20 OEU13400.1 - 1.1e-27 96.6 0.0 1.6e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OEU13400.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ABM PF03992.16 OEU13401.1 - 2.4e-14 53.2 0.3 2.6e-14 53.1 0.3 1.0 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_3 PF05977.13 OEU13401.1 - 0.018 13.4 0.3 0.019 13.4 0.3 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector RRM_1 PF00076.22 OEU13402.1 - 3.7e-11 42.7 0.0 7.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 OEU13402.1 - 0.062 12.6 13.4 0.073 12.4 13.4 1.0 1 0 0 1 1 1 0 BUD22 BLM_N PF16202.5 OEU13402.1 - 0.46 9.6 8.5 0.077 12.1 4.7 1.6 2 0 0 2 2 2 0 N-terminal region of Bloom syndrome protein ABC_tran PF00005.27 OEU13403.1 - 2.2e-25 89.8 0.1 4.2e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OEU13403.1 - 1.9e-19 70.0 4.3 5.4e-19 68.4 4.3 1.8 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OEU13403.1 - 0.00055 19.2 1.0 0.0013 17.9 1.0 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 OEU13403.1 - 0.0024 17.4 1.4 0.008 15.6 1.4 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OEU13403.1 - 0.0048 16.8 0.3 0.015 15.2 0.3 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 OEU13403.1 - 0.0085 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OEU13403.1 - 0.013 14.4 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 OEU13403.1 - 0.037 13.8 1.1 0.082 12.7 1.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OEU13403.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OEU13403.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 OEU13403.1 - 1.4 8.6 9.1 0.64 9.8 0.1 2.6 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OEU13403.1 - 4.7 7.2 5.3 2.1 8.4 2.4 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Ion_trans_2 PF07885.16 OEU13404.1 - 1.2e-06 28.4 6.7 1.7e-06 27.9 6.7 1.2 1 0 0 1 1 1 1 Ion channel EFhand_Ca_insen PF08726.10 OEU13404.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF3161 PF11362.8 OEU13404.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) 2OG-FeII_Oxy_3 PF13640.6 OEU13405.1 - 6.2e-13 49.4 0.0 1.4e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Bac_DNA_binding PF00216.21 OEU13407.1 - 1.1e-17 64.0 0.1 2e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 OEU13407.1 - 0.00052 20.1 0.0 0.00071 19.7 0.0 1.4 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif EF-G-binding_N PF07299.11 OEU13407.1 - 0.042 14.4 0.6 0.071 13.6 0.6 1.3 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal TraI_2 PF07514.11 OEU13407.1 - 0.19 10.6 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative helicase M-factor PF03855.13 OEU13407.1 - 0.23 11.6 1.3 0.51 10.5 0.1 2.1 3 0 0 3 3 3 0 M-factor NES_C_h PF18208.1 OEU13408.1 - 0.0033 17.7 1.4 0.0096 16.2 1.4 1.8 1 0 0 1 1 1 1 Nicking enzyme C-terminal middle helical domain UPF0029 PF01205.19 OEU13408.1 - 0.016 15.5 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 HLH PF00010.26 OEU13409.1 - 1.2e-09 38.0 1.0 2.9e-09 36.8 0.7 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_8 PF13188.7 OEU13409.1 - 0.003 17.5 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OEU13409.1 - 0.02 14.9 0.0 0.07 13.1 0.0 1.9 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 OEU13409.1 - 0.029 14.6 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 PAS domain MRC1 PF09444.10 OEU13409.1 - 2.2 8.8 10.3 0.063 13.8 3.5 1.9 2 0 0 2 2 2 0 MRC1-like domain Prenyltransf PF01255.19 OEU13410.1 - 8.9e-67 224.9 0.0 1e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Creatinase_N_2 PF16189.5 OEU13411.1 - 2.7e-44 151.1 0.3 8.1e-43 146.3 0.2 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OEU13411.1 - 3.6e-44 151.0 0.0 5.2e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OEU13411.1 - 2.9e-21 75.3 0.3 6.5e-21 74.2 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OEU13411.1 - 3.5e-17 63.3 0.0 1.2e-10 42.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Solute_trans_a PF03619.16 OEU13413.1 - 5.8e-52 176.8 1.7 6.7e-52 176.6 1.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PI-PLC-X PF00388.19 OEU13414.1 - 4.5e-05 23.1 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Varsurf_PPLC PF03490.13 OEU13414.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C DUF4050 PF13259.6 OEU13415.1 - 5.7 7.2 13.6 0.16 12.3 1.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4050) Multi_Drug_Res PF00893.19 OEU13416.1 - 3.1e-20 72.6 7.4 5.6e-20 71.8 7.4 1.4 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 OEU13416.1 - 7.6e-05 22.9 7.6 0.00012 22.2 7.6 1.4 1 0 0 1 1 1 1 EamA-like transporter family DUF969 PF06149.12 OEU13416.1 - 0.0081 15.6 4.8 0.016 14.7 4.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF969) TPT PF03151.16 OEU13416.1 - 0.019 14.3 2.3 0.026 13.9 2.3 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family TMEM43 PF07787.12 OEU13416.1 - 0.034 13.5 0.9 0.049 13.0 0.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 PUNUT PF16913.5 OEU13416.1 - 0.051 12.8 5.3 0.065 12.4 3.7 1.8 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport TMEM234 PF10639.9 OEU13416.1 - 0.056 13.5 0.6 0.11 12.6 0.6 1.5 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF2530 PF10745.9 OEU13416.1 - 0.066 13.5 3.5 0.6 10.4 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Nudc_N PF14050.6 OEU13416.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. DUF5381 PF17353.2 OEU13416.1 - 1.2 8.9 6.6 0.32 10.8 1.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5381) zf-CCCH PF00642.24 OEU13417.1 - 0.00082 19.2 4.8 0.48 10.4 0.3 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU13417.1 - 0.057 13.5 5.3 2.7 8.2 0.2 3.0 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 OEU13417.1 - 1.3 9.6 7.5 12 6.5 1.7 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 OEU13417.1 - 1.7 8.5 5.9 2.9 7.8 0.9 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger GnRH PF00446.17 OEU13418.1 - 0.062 13.7 1.2 0.14 12.6 1.2 1.6 1 0 0 1 1 1 0 Gonadotropin-releasing hormone UCH PF00443.29 OEU13419.1 - 3.2e-26 92.4 0.0 3.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU13419.1 - 3.3e-13 49.9 0.0 4.2e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Insulin_TMD PF17870.1 OEU13420.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RNA_pol_Rpc82 PF05645.13 OEU13420.1 - 0.092 12.5 5.8 0.065 13.0 2.5 2.5 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Orf78 PF06024.12 OEU13420.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.0 2 0 0 2 2 2 0 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 OEU13420.1 - 0.12 12.2 0.3 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CcmD PF04995.14 OEU13420.1 - 2.6 8.2 4.1 0.84 9.8 0.2 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ABC2_membrane_3 PF12698.7 OEU13420.1 - 4.2 6.4 11.0 0.22 10.6 4.6 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein FANCI_HD1 PF14679.6 OEU13421.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 FANCI helical domain 1 Pyridox_oxase_2 PF12766.7 OEU13421.1 - 0.099 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SUIM_assoc PF16619.5 OEU13423.1 - 1.5 8.9 15.4 6 7.0 1.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TCP PF03634.13 OEU13423.1 - 4.1 7.9 11.4 0.33 11.5 0.3 3.1 3 0 0 3 3 3 0 TCP family transcription factor TPR_2 PF07719.17 OEU13424.1 - 1.7e-10 40.2 0.4 0.00014 21.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13424.1 - 3.2e-09 36.2 0.0 0.0012 18.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OEU13424.1 - 1.5e-05 25.1 0.7 2.2e-05 24.5 0.7 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU13424.1 - 4.3e-05 23.4 0.0 0.00066 19.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU13424.1 - 6.4e-05 23.2 0.8 0.0089 16.3 0.6 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU13424.1 - 0.00018 21.1 1.3 0.035 13.8 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_15 PF13429.6 OEU13424.1 - 0.00026 20.3 0.3 0.00031 20.1 0.3 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Desmo_N PF06771.11 OEU13424.1 - 0.00054 20.3 0.2 0.8 10.1 0.0 2.3 1 1 1 2 2 2 2 Viral Desmoplakin N-terminus TPR_16 PF13432.6 OEU13424.1 - 0.0023 18.5 0.8 0.0036 17.9 0.8 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU13424.1 - 0.0039 17.5 0.3 17 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU13424.1 - 0.0071 15.8 1.0 1.6 8.3 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR NYD-SP12_N PF15015.6 OEU13424.1 - 0.0088 14.5 0.3 0.012 14.1 0.2 1.3 1 1 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_14 PF13428.6 OEU13424.1 - 0.011 16.5 0.8 0.14 13.1 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribos_L4_asso_C PF14374.6 OEU13424.1 - 0.044 13.8 0.7 0.068 13.2 0.7 1.2 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain Acid_phosphat_B PF03767.14 OEU13424.1 - 0.077 12.6 0.2 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LsmAD PF06741.13 OEU13425.1 - 5.3e-23 81.4 1.9 5.3e-23 81.4 1.9 2.8 2 1 1 3 3 3 1 LsmAD domain SM-ATX PF14438.6 OEU13425.1 - 3.1e-08 33.6 2.5 3.9e-08 33.3 0.0 2.6 2 0 0 2 2 2 1 Ataxin 2 SM domain PAM2 PF07145.15 OEU13425.1 - 0.028 14.1 4.4 0.1 12.3 0.9 2.7 1 1 1 2 2 2 0 Ataxin-2 C-terminal region DUF1800 PF08811.11 OEU13426.1 - 1.6e-46 159.2 0.0 7.8e-22 77.9 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1800) DUF1501 PF07394.12 OEU13426.1 - 1.1e-29 103.7 1.0 1.1e-28 100.5 1.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) Sulfatase PF00884.23 OEU13426.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Sulfatase PP2C_2 PF13672.6 OEU13428.1 - 0.035 13.8 0.3 0.25 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein phosphatase 2C FTZ PF03867.14 OEU13428.1 - 1.1 8.8 5.0 0.96 8.9 0.7 2.7 3 0 0 3 3 3 0 Fushi tarazu (FTZ), N-terminal region Pkinase PF00069.25 OEU13429.1 - 5e-52 176.9 0.0 6e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13429.1 - 3.6e-36 124.8 0.0 4.3e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DP-EP PF08985.11 OEU13429.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 DP-EP family Vps5 PF09325.10 OEU13430.1 - 0.051 13.1 13.4 0.061 12.9 13.4 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Tim17 PF02466.19 OEU13431.1 - 1.9e-06 28.2 0.2 3.1e-06 27.5 0.2 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HA PF03457.14 OEU13432.1 - 1e-24 86.7 0.0 1.8e-09 37.8 0.0 6.1 5 1 0 5 5 5 5 Helicase associated domain LETM1 PF07766.13 OEU13434.1 - 1.2e-12 47.8 0.4 4.4e-12 45.9 0.1 2.0 2 1 0 2 2 2 1 LETM1-like protein GlcNAc PF11397.8 OEU13435.1 - 8.6e-53 180.0 2.0 7.2e-41 140.8 0.6 2.6 1 1 0 2 2 2 2 Glycosyltransferase (GlcNAc) DUF5320 PF17253.2 OEU13436.1 - 0.08 14.0 0.1 0.08 14.0 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) bZIP_1 PF00170.21 OEU13436.1 - 0.084 13.0 1.2 0.22 11.6 1.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor APG6_N PF17675.1 OEU13436.1 - 0.091 13.3 4.1 0.15 12.6 4.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MatE PF01554.18 OEU13437.1 - 1.9e-20 73.2 24.9 2.7e-11 43.4 1.6 4.3 3 1 1 4 4 4 3 MatE Polysacc_synt_C PF14667.6 OEU13437.1 - 1e-11 45.1 6.9 1e-11 45.1 6.9 3.7 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DUF2106 PF09879.9 OEU13437.1 - 0.089 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) DUF4461 PF14688.6 OEU13438.1 - 2.1e-15 57.3 0.1 2.3e-15 57.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 OEU13439.1 - 0.069 13.2 0.5 0.52 10.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4460) MMR_HSR1 PF01926.23 OEU13440.1 - 1.4e-12 47.7 0.0 3.7e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU13440.1 - 2.9e-06 26.9 0.0 0.0048 16.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OEU13440.1 - 5.2e-05 23.2 0.0 0.0053 16.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase YL1 PF05764.13 OEU13441.1 - 0.00022 21.4 2.3 0.00034 20.8 2.3 1.3 1 1 0 1 1 1 1 YL1 nuclear protein HAS-barrel PF09378.10 OEU13441.1 - 0.11 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 HAS barrel domain Connexin PF00029.19 OEU13441.1 - 0.25 11.1 1.5 0.34 10.6 0.5 1.8 1 1 1 2 2 2 0 Connexin Nop16 PF09420.10 OEU13441.1 - 0.39 10.7 6.3 0.22 11.6 3.1 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Myc_N PF01056.18 OEU13441.1 - 0.97 9.3 6.2 2.1 8.1 5.9 1.5 1 1 1 2 2 2 0 Myc amino-terminal region PGA2 PF07543.12 OEU13441.1 - 4 7.4 7.6 0.24 11.4 2.1 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 TPR_1 PF00515.28 OEU13442.1 - 0.00023 20.8 2.1 0.14 12.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT PF02985.22 OEU13442.1 - 0.00027 21.0 1.5 6.9 7.2 0.2 5.1 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 OEU13442.1 - 0.00027 20.9 2.5 67 3.7 0.0 6.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF2877 PF11392.8 OEU13442.1 - 0.045 14.5 2.4 0.24 12.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2877) TFA2_Winged_2 PF18121.1 OEU13442.1 - 0.052 13.2 0.0 3.9 7.3 0.0 2.8 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 PBP1_TM PF14812.6 OEU13442.1 - 8.7 6.8 15.4 1.6 9.2 0.7 4.1 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfatase PF00884.23 OEU13443.1 - 1.9e-51 175.3 0.5 1.3e-50 172.6 0.5 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU13443.1 - 2.4e-06 27.4 1.2 1.2e-05 25.2 1.2 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Olfactory_mark PF06554.12 OEU13443.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Olfactory marker protein LysM PF01476.20 OEU13445.1 - 0.021 14.9 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 LysM domain UBA_4 PF14555.6 OEU13445.1 - 0.051 13.4 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 UBA-like domain DHDPS PF00701.22 OEU13446.1 - 1.1e-83 280.3 0.0 1.3e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family T2SSppdC PF12528.8 OEU13446.1 - 0.056 14.2 0.3 0.75 10.6 0.0 2.2 1 1 1 2 2 2 0 Type II secretion prepilin peptidase dependent protein C UPF0086 PF01868.16 OEU13447.1 - 0.024 14.5 0.1 0.08 12.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function UPF0086 Ribosomal_L44 PF00935.19 OEU13448.1 - 2.3e-31 108.1 14.5 3.1e-31 107.7 14.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Sar8_2 PF03058.14 OEU13448.1 - 1.6 9.3 6.0 2.7 8.6 6.0 1.6 1 1 0 1 1 1 0 Sar8.2 family TAF6_C PF07571.13 OEU13449.1 - 1.8e-18 66.7 0.0 3.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain PDCD2_C PF04194.13 OEU13450.1 - 1e-29 103.8 6.9 1e-29 103.8 6.9 3.1 2 2 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Hpr_kinase_N PF02603.16 OEU13452.1 - 0.00069 19.6 0.5 0.0036 17.3 0.1 2.2 1 1 1 2 2 2 1 HPr Serine kinase N terminus FAM184 PF15665.5 OEU13452.1 - 0.025 14.4 3.4 0.059 13.1 3.4 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B BLOC1_2 PF10046.9 OEU13452.1 - 0.028 14.7 0.7 0.028 14.7 0.7 2.3 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KfrA_N PF11740.8 OEU13452.1 - 0.047 14.4 2.8 0.064 13.9 1.0 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Val_tRNA-synt_C PF10458.9 OEU13452.1 - 0.048 13.9 0.5 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm OmpH PF03938.14 OEU13452.1 - 0.068 13.5 4.0 0.12 12.7 4.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HBM PF16591.5 OEU13452.1 - 0.089 12.2 6.4 0.54 9.6 1.3 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain TRAF_BIRC3_bd PF16673.5 OEU13452.1 - 0.16 11.8 2.2 0.16 11.8 0.5 1.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF4615 PF15393.6 OEU13452.1 - 0.3 11.7 0.2 0.3 11.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) DUF5082 PF16888.5 OEU13452.1 - 0.41 10.9 4.9 0.4 11.0 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 OEU13452.1 - 0.41 11.0 5.8 0.18 12.2 2.8 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ABC_tran_CTD PF16326.5 OEU13452.1 - 3.3 8.0 8.7 31 4.9 5.2 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain XhlA PF10779.9 OEU13452.1 - 4 7.7 5.4 1.1 9.5 1.5 2.0 2 0 0 2 2 2 0 Haemolysin XhlA 2-oxoacid_dh PF00198.23 OEU13453.1 - 1.6e-51 175.0 0.0 2.1e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OEU13453.1 - 7.2e-13 48.2 0.4 7.2e-13 48.2 0.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OEU13453.1 - 6.2e-12 45.6 0.9 2e-11 44.0 0.1 2.4 2 0 0 2 2 2 1 e3 binding domain Clp_N PF02861.20 OEU13453.1 - 0.067 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component DEC-1_N PF04625.13 OEU13453.1 - 0.081 11.9 14.9 0.12 11.4 14.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF839 PF05787.13 OEU13455.1 - 0.0037 16.5 0.0 0.0043 16.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) NPR2 PF06218.11 OEU13456.1 - 2.7e-50 171.4 0.4 5.3e-42 144.1 0.0 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Afi1 PF07792.12 OEU13456.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Bestrophin PF01062.21 OEU13457.1 - 2.2e-22 79.8 0.9 2.9e-22 79.4 0.9 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4633 PF15464.6 OEU13457.1 - 0.045 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) SapC PF07277.11 OEU13457.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 SapC Herpes_UL25 PF01499.16 OEU13458.1 - 0.09 11.3 1.8 0.16 10.5 1.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family SDA1 PF05285.12 OEU13458.1 - 0.1 12.0 14.7 0.14 11.6 14.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OEU13458.1 - 0.16 10.3 11.7 0.19 10.0 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OEU13458.1 - 2.5 6.2 14.6 3.2 5.9 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family MORN PF02493.20 OEU13460.1 - 9.5e-30 100.7 23.1 3.2e-07 29.9 0.3 6.0 6 0 0 6 6 6 6 MORN repeat Ecl1 PF12855.7 OEU13461.1 - 4.7 8.3 9.2 8.9 7.4 9.2 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Fapy_DNA_glyco PF01149.24 OEU13462.1 - 2.5e-16 60.4 0.0 4.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 OEU13462.1 - 7e-14 51.6 0.1 1.2e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Peptidase_A22B PF04258.13 OEU13463.1 - 6.5e-57 193.2 9.4 1e-56 192.6 9.4 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 OEU13463.1 - 0.00039 20.4 0.0 0.021 14.9 0.0 2.5 2 0 0 2 2 2 1 PA domain cNMP_binding PF00027.29 OEU13464.1 - 1.4e-36 124.4 0.3 6.4e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 OEU13465.1 - 2.5e-60 204.1 0.0 2.9e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13465.1 - 2e-34 119.1 0.0 2.5e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU13465.1 - 0.00079 19.4 0.0 0.0019 18.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU13465.1 - 0.03 13.1 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OEU13465.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Lon_C PF05362.13 OEU13466.1 - 1.3e-70 237.1 0.1 4.6e-70 235.3 0.0 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OEU13466.1 - 1.6e-27 96.7 0.4 6.9e-27 94.7 0.0 2.0 1 1 1 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OEU13466.1 - 3.7e-24 85.6 0.0 1.1e-23 84.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU13466.1 - 1.8e-07 31.3 0.0 3.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OEU13466.1 - 6.3e-07 29.7 0.1 1.9e-06 28.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 OEU13466.1 - 2e-06 27.7 0.0 5.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 OEU13466.1 - 2.2e-06 28.0 1.0 0.00017 21.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 OEU13466.1 - 0.00011 21.3 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 OEU13466.1 - 0.00026 21.4 2.7 0.0012 19.3 0.1 2.9 3 1 0 3 3 2 1 AAA ATPase domain AAA_3 PF07726.11 OEU13466.1 - 0.00034 20.5 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OEU13466.1 - 0.00035 21.1 0.1 0.0013 19.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU13466.1 - 0.00042 20.1 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OEU13466.1 - 0.0013 18.0 0.1 0.0029 16.9 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 OEU13466.1 - 0.0059 16.4 0.1 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OEU13466.1 - 0.0075 16.3 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OEU13466.1 - 0.0095 15.9 0.1 0.15 12.0 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_24 PF13479.6 OEU13466.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OEU13466.1 - 0.011 15.5 0.6 0.071 12.8 0.0 2.4 3 0 0 3 3 2 0 Cytidylate kinase RNA_helicase PF00910.22 OEU13466.1 - 0.015 15.7 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 OEU13466.1 - 0.018 15.1 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OEU13466.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 OEU13466.1 - 0.026 14.9 0.1 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU13466.1 - 0.028 14.3 0.0 0.62 10.0 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 OEU13466.1 - 0.035 14.3 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 OEU13466.1 - 0.044 12.9 0.1 0.1 11.7 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain PRESAN PF09687.10 OEU13466.1 - 0.049 14.2 4.4 0.037 14.6 2.3 1.8 1 1 1 2 2 1 0 Plasmodium RESA N-terminal AAA_28 PF13521.6 OEU13466.1 - 0.079 13.2 0.2 0.29 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OEU13466.1 - 0.085 12.2 0.2 0.52 9.7 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OEU13466.1 - 0.096 12.2 0.8 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_6 PF12774.7 OEU13466.1 - 0.11 11.5 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 OEU13466.1 - 0.11 12.0 0.5 0.28 10.7 0.1 1.8 2 0 0 2 2 1 0 AAA domain MiaE_2 PF13794.6 OEU13466.1 - 0.19 11.4 0.2 0.39 10.4 0.2 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Cytidylate_kin2 PF13189.6 OEU13466.1 - 0.22 11.6 1.3 0.32 11.1 0.0 1.9 2 1 0 2 2 1 0 Cytidylate kinase-like family DnaB_C PF03796.15 OEU13466.1 - 0.23 10.8 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 1 0 DnaB-like helicase C terminal domain AAA_11 PF13086.6 OEU13466.1 - 0.26 11.0 5.6 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OEU13466.1 - 0.74 10.2 3.4 2.6 8.5 0.1 3.0 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 OEU13466.1 - 1.3 9.5 3.2 1.9 9.0 0.1 2.3 2 0 0 2 2 2 0 ABC transporter UPF0242 PF06785.11 OEU13466.1 - 1.8 8.6 10.7 3.3 7.8 10.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 OEU13466.1 - 3.3 7.9 7.6 7.4 6.7 7.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GFO_IDH_MocA PF01408.22 OEU13467.1 - 3.6e-13 50.4 0.1 1.9e-12 48.1 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold RRM_3 PF08777.11 OEU13469.1 - 5.1e-13 48.9 6.4 3.5e-12 46.3 0.2 3.6 4 1 0 4 4 4 1 RNA binding motif La PF05383.17 OEU13469.1 - 1.2e-10 41.2 0.1 2.3e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OEU13469.1 - 0.0011 18.8 0.1 2.7 7.9 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas1 PF01867.16 OEU13469.1 - 0.096 11.8 0.1 0.44 9.7 0.0 1.9 2 0 0 2 2 2 0 CRISPR associated protein Cas1 AhpC-TSA_2 PF13911.6 OEU13470.1 - 4.7e-08 33.1 0.0 5.7e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme KRAB PF01352.27 OEU13470.1 - 0.2 11.4 0.1 0.65 9.7 0.0 1.8 2 0 0 2 2 2 0 KRAB box DUF1836 PF08876.11 OEU13471.1 - 0.21 11.6 7.1 0.84 9.7 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1836) CemA PF03040.14 OEU13471.1 - 0.77 9.6 4.2 1.4 8.8 0.4 2.6 2 0 0 2 2 2 0 CemA family Drf_FH1 PF06346.12 OEU13472.1 - 0.021 14.6 0.8 0.021 14.6 0.8 1.9 2 0 0 2 2 2 0 Formin Homology Region 1 Ribo_biogen_C PF04034.13 OEU13474.1 - 2.9e-45 153.1 0.0 3.8e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OEU13474.1 - 8.4e-10 38.3 0.2 1.4e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI dCMP_cyt_deam_1 PF00383.23 OEU13476.1 - 1.3e-07 31.4 0.1 3.2e-07 30.2 0.1 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OEU13476.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OEU13476.1 - 0.029 14.4 0.1 0.13 12.3 0.1 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase efThoc1 PF11957.8 OEU13477.1 - 0.021 13.5 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor DUF4080 PF13311.6 OEU13478.1 - 0.075 13.2 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) UbiA PF01040.18 OEU13480.1 - 5.3e-35 120.9 10.6 7e-35 120.5 10.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Asn_synthase PF00733.21 OEU13481.1 - 3.1e-90 303.4 0.0 3.5e-55 188.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OEU13481.1 - 2.2e-37 127.7 0.0 3.5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OEU13481.1 - 1.1e-29 103.3 0.0 1.7e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OEU13481.1 - 6.8e-13 48.6 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 OEU13481.1 - 0.0032 16.6 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Sulfotransfer_2 PF03567.14 OEU13482.1 - 1e-20 74.7 1.5 1.7e-20 74.0 1.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF2730 PF10805.8 OEU13483.1 - 8.9 6.5 8.5 1.2 9.2 1.6 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) Lipase_3 PF01764.25 OEU13484.1 - 1e-12 48.1 0.0 2.4e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OEU13484.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) ABC_ATPase PF09818.9 OEU13486.1 - 2.7e-158 527.4 0.0 3.5e-158 527.1 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 OEU13486.1 - 0.00018 22.1 0.2 0.00038 21.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain Na_H_Exchanger PF00999.21 OEU13487.1 - 7.2e-45 153.4 23.9 1.2e-37 129.6 15.9 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family ClpS PF02617.17 OEU13488.1 - 2.9e-08 33.4 0.9 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS BDHCT PF08072.11 OEU13488.1 - 0.17 12.0 0.8 0.31 11.2 0.8 1.4 1 0 0 1 1 1 0 BDHCT (NUC031) domain Ank_2 PF12796.7 OEU13489.1 - 8.1e-27 93.6 0.0 4.9e-09 36.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU13489.1 - 5.3e-22 77.6 2.5 2.3e-06 27.7 0.0 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU13489.1 - 5.6e-21 74.6 1.5 1.1e-05 25.8 0.0 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU13489.1 - 2e-19 67.6 0.1 0.083 13.5 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 OEU13489.1 - 3.9e-18 65.0 0.0 0.026 15.0 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat mTERF PF02536.14 OEU13489.1 - 0.00054 19.0 0.9 0.54 9.1 0.0 2.8 3 0 0 3 3 3 2 mTERF F-112 PF09645.10 OEU13489.1 - 1.6 8.9 6.9 0.75 9.9 3.6 2.2 2 0 0 2 2 2 0 F-112 protein Kelch_4 PF13418.6 OEU13491.1 - 8e-31 105.8 8.5 2.5e-07 30.6 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OEU13491.1 - 3.7e-28 97.0 0.0 6.5e-07 29.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OEU13491.1 - 3e-19 68.8 22.6 0.00022 21.4 0.1 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OEU13491.1 - 3.3e-18 64.9 6.2 0.00012 21.9 0.1 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OEU13491.1 - 2.3e-11 43.5 6.3 0.02 15.2 0.1 6.3 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OEU13491.1 - 6.4e-10 38.5 9.7 0.38 10.4 0.1 5.7 5 0 0 5 5 5 4 Kelch motif E1-E2_ATPase PF00122.20 OEU13492.1 - 0.00033 20.2 5.6 0.022 14.3 0.0 3.8 4 0 0 4 4 4 1 E1-E2 ATPase PI-PLC-X PF00388.19 OEU13492.1 - 0.052 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF4131 PF13567.6 OEU13492.1 - 2.8 7.6 8.4 16 5.1 2.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DNA_topoisoIV PF00521.20 OEU13493.1 - 3.5e-123 411.7 0.1 7e-123 410.7 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OEU13493.1 - 1.3e-43 148.3 2.2 3.2e-43 147.0 2.2 1.7 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OEU13493.1 - 1.9e-23 82.9 0.5 4.7e-23 81.5 0.1 1.8 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 OEU13493.1 - 5.3e-14 52.7 0.4 2.4e-13 50.6 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OEU13493.1 - 2.6e-06 27.6 0.0 7.8e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain DUF4570 PF15134.6 OEU13493.1 - 2.5 8.2 4.6 1.1 9.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Ribosomal_S9 PF00380.19 OEU13494.1 - 7.2e-45 152.4 0.0 8.3e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAA PF00004.29 OEU13495.1 - 1.3e-28 100.1 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OEU13495.1 - 7.1e-07 29.6 0.3 7.5e-06 26.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU13495.1 - 4.4e-06 26.7 0.2 1.2e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OEU13495.1 - 1.7e-05 25.2 0.0 3.3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 OEU13495.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OEU13495.1 - 0.0003 20.8 0.4 0.00058 19.8 0.4 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 OEU13495.1 - 0.0014 19.1 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OEU13495.1 - 0.0044 17.1 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OEU13495.1 - 0.0054 17.1 0.0 0.02 15.3 0.0 1.9 1 1 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 OEU13495.1 - 0.0089 16.2 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU13495.1 - 0.014 15.4 0.1 0.092 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU13495.1 - 0.024 14.0 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OEU13495.1 - 0.032 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OEU13495.1 - 0.053 13.9 0.2 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OEU13495.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OEU13495.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OEU13495.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OEU13495.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 OEU13495.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.19 OEU13496.1 - 6.4e-28 97.0 9.1 2.3e-21 76.0 1.8 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU13496.1 - 1.5e-16 60.7 7.9 4.6e-11 43.2 1.2 2.2 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 OEU13496.1 - 0.029 14.3 0.0 0.2 11.6 0.0 2.3 2 1 1 3 3 3 0 CHDNT (NUC034) domain Sec63 PF02889.16 OEU13497.1 - 1.4e-148 493.0 0.9 3e-78 262.5 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OEU13497.1 - 4.8e-52 176.3 0.0 1e-25 90.6 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OEU13497.1 - 4.9e-28 98.3 0.0 1.3e-14 54.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 OEU13497.1 - 5.6e-27 94.1 1.2 2.2e-26 92.2 0.8 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain Helicase_C PF00271.31 OEU13497.1 - 9.8e-12 45.2 0.0 1.3e-06 28.7 0.0 3.9 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OEU13497.1 - 6.8e-09 36.1 0.0 0.0087 16.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OEU13497.1 - 4.3e-07 29.8 0.0 0.011 15.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 OEU13497.1 - 0.00095 19.5 0.0 0.28 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OEU13497.1 - 0.0031 17.3 0.0 0.88 9.3 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 OEU13497.1 - 0.0072 15.9 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_11 PF13086.6 OEU13497.1 - 0.018 14.9 0.0 2.8 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OEU13497.1 - 0.022 14.3 0.0 2.4 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU13497.1 - 0.025 14.9 0.0 13 6.1 0.0 3.2 3 0 0 3 3 2 0 AAA ATPase domain Ank_2 PF12796.7 OEU13498.1 - 1.8e-20 73.3 0.9 3.1e-10 40.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU13498.1 - 2.5e-10 40.7 0.1 2.3e-05 24.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU13498.1 - 3.5e-08 33.1 0.0 1.1e-06 28.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU13498.1 - 2.6e-05 24.5 0.0 0.00035 20.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OEU13498.1 - 0.0015 18.8 0.3 0.022 15.1 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF5480 PF17576.2 OEU13499.1 - 0.087 12.8 0.1 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Nup54 PF13874.6 OEU13501.1 - 6.2e-21 75.0 4.5 6.2e-21 75.0 4.5 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 OEU13501.1 - 0.0023 18.7 10.2 0.0023 18.7 10.2 2.3 2 0 0 2 2 2 1 Nucleoporin FG repeat region Med3 PF11593.8 OEU13501.1 - 2 7.5 8.6 0.37 9.9 5.0 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SnoaL_2 PF12680.7 OEU13502.1 - 8.4e-12 45.6 0.0 1.6e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain RSN1_7TM PF02714.15 OEU13504.1 - 6.1e-47 160.2 11.1 7.5e-47 159.9 11.1 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 OEU13504.1 - 0.11 11.4 3.0 0.38 9.6 0.0 2.2 1 1 0 2 2 2 0 Calcium-activated chloride channel LNS2 PF08235.13 OEU13505.1 - 1.1e-40 139.6 0.1 1.2e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RRM_1 PF00076.22 OEU13506.1 - 1.3e-22 79.4 0.0 1.1e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 OEU13506.1 - 3.2e-09 37.3 5.5 5.9e-09 36.5 5.5 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_occluded PF16842.5 OEU13506.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif 2Fe-2S_thioredx PF01257.19 OEU13507.1 - 9.2e-05 22.3 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DEAD PF00270.29 OEU13508.1 - 5.2e-49 166.4 0.0 3.1e-48 163.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU13508.1 - 2.7e-25 88.9 0.0 2.8e-24 85.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU13508.1 - 0.00012 22.1 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OEU13508.1 - 0.00039 19.7 0.0 0.00063 19.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase WLM PF08325.10 OEU13509.1 - 0.2 11.7 1.7 0.29 11.2 1.5 1.4 1 1 0 1 1 1 0 WLM domain LapA_dom PF06305.11 OEU13509.1 - 8.2 6.3 5.4 22 4.9 5.4 1.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GvpL_GvpF PF06386.11 OEU13510.1 - 0.23 11.3 1.8 0.46 10.4 0.0 2.2 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF KIND PF16474.5 OEU13510.1 - 2 8.2 10.1 0.31 10.9 0.3 3.1 1 1 3 4 4 4 0 Kinase non-catalytic C-lobe domain TSC22 PF01166.18 OEU13511.1 - 7.2 7.0 22.5 2.4 8.5 1.3 4.1 2 1 2 4 4 4 0 TSC-22/dip/bun family YabA PF06156.13 OEU13511.1 - 9.2 7.0 25.5 57 4.4 1.8 3.5 1 1 2 3 3 3 0 Initiation control protein YabA HpcH_HpaI PF03328.14 OEU13512.1 - 9.7e-25 87.0 0.0 1.1e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 OEU13512.1 - 0.0086 15.5 0.0 0.043 13.3 0.0 1.9 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PK PF00224.21 OEU13512.1 - 0.022 13.7 0.1 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Tropomyosin_1 PF12718.7 OEU13513.1 - 0.0021 18.2 25.1 0.036 14.2 5.5 3.2 1 1 2 3 3 3 2 Tropomyosin like DUF4472 PF14739.6 OEU13513.1 - 0.022 15.5 2.3 0.022 15.5 2.3 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4472) CALCOCO1 PF07888.11 OEU13513.1 - 0.025 13.5 20.2 0.035 13.0 20.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3958 PF13125.6 OEU13513.1 - 0.39 11.0 11.1 0.16 12.2 0.4 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3958) Csm1_N PF18504.1 OEU13513.1 - 0.63 10.4 18.5 1 9.7 0.3 5.0 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF724 PF05266.14 OEU13513.1 - 0.69 9.7 17.3 0.14 11.9 1.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) PI3K_P85_iSH2 PF16454.5 OEU13513.1 - 0.88 9.2 19.1 0.17 11.5 1.0 3.9 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Atg14 PF10186.9 OEU13513.1 - 0.93 8.5 12.7 4 6.4 12.5 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 OEU13513.1 - 1.8 8.5 19.4 0.11 12.5 6.1 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 OEU13513.1 - 2.6 8.1 25.5 0.35 10.9 1.7 5.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding LPP PF04728.13 OEU13513.1 - 3.8 8.0 13.7 1.3 9.5 0.2 4.4 5 1 0 5 5 5 0 Lipoprotein leucine-zipper CLZ PF16526.5 OEU13513.1 - 4.6 7.7 18.3 0.19 12.1 1.2 4.0 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Shugoshin_N PF07558.11 OEU13513.1 - 6.3 6.8 9.1 0.71 9.8 0.5 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Ribosomal_L37ae PF01780.19 OEU13515.1 - 7.4e-39 131.7 8.8 8.4e-39 131.6 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family CarbpepA_inh PF02977.15 OEU13515.1 - 0.018 14.8 3.3 0.054 13.3 3.3 1.8 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor Zn_Tnp_IS1595 PF12760.7 OEU13515.1 - 0.3 11.1 4.9 0.53 10.3 4.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Clathrin PF00637.20 OEU13516.1 - 1.1e-157 518.2 14.5 9.1e-25 87.2 1.5 7.9 7 1 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OEU13516.1 - 7.9e-25 86.6 0.7 3.2e-24 84.6 0.6 2.2 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 OEU13516.1 - 4.1e-11 42.6 0.5 0.011 16.0 0.0 5.5 5 0 0 5 5 5 2 Clathrin propeller repeat Clathrin-link PF09268.10 OEU13516.1 - 5.9e-07 28.7 0.2 2.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_2 PF07719.17 OEU13516.1 - 0.00052 19.9 0.5 6.6 7.1 0.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 OEU13516.1 - 0.0028 16.7 2.7 8.7 5.3 0.0 4.1 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 OEU13516.1 - 0.005 16.8 0.7 10 6.4 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat PQQ_2 PF13360.6 OEU13516.1 - 0.019 14.6 0.5 3.1 7.3 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 OEU13516.1 - 0.057 13.4 1.2 0.18 11.8 0.0 2.4 3 0 0 3 3 2 0 PQQ enzyme repeat TPR_1 PF00515.28 OEU13516.1 - 0.12 12.2 0.1 19 5.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 OEU13516.1 - 0.38 11.1 4.2 10 6.4 0.1 4.3 5 0 0 5 5 5 0 Vacuolar sorting protein 39 domain 1 RNase_J_C PF17770.1 OEU13517.1 - 0.14 13.2 0.0 6.6 7.9 0.0 3.0 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain Sigma70_r2 PF04542.14 OEU13518.1 - 5.2e-15 55.0 0.1 2e-14 53.1 0.1 2.1 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 OEU13518.1 - 2.2e-14 53.3 3.5 2.8e-12 46.5 0.8 3.7 3 1 0 3 3 3 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 OEU13518.1 - 8.2e-13 47.7 1.3 2.6e-12 46.1 0.6 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 OEU13518.1 - 0.0011 18.6 0.9 0.0011 18.6 0.9 2.6 2 1 0 2 2 2 1 Sigma-70, region 4 adh_short PF00106.25 OEU13518.1 - 0.13 11.7 0.3 0.6 9.5 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase AMP-binding PF00501.28 OEU13519.1 - 2.3e-66 224.1 0.0 2.9e-56 190.9 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OEU13519.1 - 3.4e-15 56.8 0.1 6.1e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Choline_transpo PF04515.12 OEU13520.1 - 5e-15 55.5 0.0 6.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter Nitrate_red_gam PF02665.14 OEU13520.1 - 0.00075 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Nitrate reductase gamma subunit LAP1C PF05609.12 OEU13520.1 - 0.78 8.8 9.7 1.1 8.3 9.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 OEU13520.1 - 5.2 6.3 21.1 7.8 5.7 21.1 1.2 1 0 0 1 1 1 0 BUD22 ABC_membrane PF00664.23 OEU13521.1 - 4.7e-58 197.0 25.2 4.7e-30 105.2 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU13521.1 - 5.1e-46 156.6 0.1 1.8e-26 93.3 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OEU13521.1 - 1.5e-07 31.1 6.3 0.0041 16.6 0.5 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU13521.1 - 1.1e-06 28.7 1.4 0.038 14.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU13521.1 - 5.2e-05 23.2 0.8 0.078 12.9 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OEU13521.1 - 7.8e-05 22.3 0.3 0.41 10.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU13521.1 - 0.0011 19.5 3.4 0.58 10.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.9 OEU13521.1 - 0.0016 17.4 0.5 0.85 8.5 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Orai-1 PF07856.12 OEU13521.1 - 0.0028 17.4 1.4 0.0055 16.4 0.1 2.2 2 0 0 2 2 2 1 Mediator of CRAC channel activity Dynamin_N PF00350.23 OEU13521.1 - 0.0039 17.3 9.7 0.0057 16.7 0.7 2.7 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.17 OEU13521.1 - 0.0068 16.5 7.2 0.018 15.1 0.1 2.8 3 0 0 3 3 3 1 Helicase HerA, central domain NACHT PF05729.12 OEU13521.1 - 0.008 16.1 0.3 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 OEU13521.1 - 0.0082 15.2 0.3 1.6 7.7 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 OEU13521.1 - 0.013 15.7 0.4 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OEU13521.1 - 0.02 14.2 0.2 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 OEU13521.1 - 0.024 13.8 0.4 2 7.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 OEU13521.1 - 0.029 14.1 5.4 7.1 6.3 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OEU13521.1 - 0.043 13.5 2.0 2.7 7.7 0.4 3.3 3 1 0 3 3 2 0 AAA domain AIG1 PF04548.16 OEU13521.1 - 0.079 12.3 2.3 4 6.7 0.4 2.4 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 OEU13521.1 - 0.091 12.3 2.8 3.9 7.0 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OEU13521.1 - 0.1 13.0 0.4 24 5.3 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 OEU13521.1 - 0.12 12.2 1.0 5.6 6.7 0.0 2.6 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 OEU13521.1 - 0.16 11.4 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OEU13521.1 - 0.99 9.8 3.9 15 6.0 0.0 3.5 4 0 0 4 4 3 0 RNA helicase SKA1 PF07160.12 OEU13522.1 - 0.82 9.5 0.0 0.82 9.5 0.0 3.7 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 1 NOA36 PF06524.12 OEU13522.1 - 1.4 8.2 5.0 3 7.1 5.0 1.6 1 0 0 1 1 1 0 NOA36 protein Ank_2 PF12796.7 OEU13523.1 - 1.1e-16 61.2 2.0 2.7e-05 24.7 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU13523.1 - 1.8e-13 49.3 5.5 0.066 13.8 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OEU13523.1 - 2.9e-10 40.5 1.8 0.00098 19.7 0.0 4.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU13523.1 - 1.5e-09 37.9 0.0 0.01 16.1 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU13523.1 - 1.4e-07 31.6 7.6 0.028 14.9 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat ribosomal_L24 PF17136.4 OEU13524.1 - 5.5e-13 49.1 0.3 5.5e-13 49.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 OEU13524.1 - 0.042 13.8 0.2 0.042 13.8 0.2 2.9 3 0 0 3 3 3 0 KOW motif Dymeclin PF09742.9 OEU13525.1 - 3.6e-64 217.3 4.5 2.9e-63 214.3 4.5 1.9 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SH2_2 PF14633.6 OEU13526.1 - 8.1e-52 175.8 0.0 1.8e-51 174.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 OEU13526.1 - 2e-17 63.4 0.0 4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 OEU13526.1 - 7.8e-11 42.4 0.1 2.5e-10 40.8 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.23 OEU13526.1 - 9e-08 32.4 1.4 1.6e-07 31.5 0.3 2.1 2 0 0 2 2 2 1 S1 RNA binding domain YqgF PF14639.6 OEU13526.1 - 1.7e-06 27.9 0.0 4.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_9 PF17674.1 OEU13526.1 - 0.0037 18.1 3.0 0.0083 17.0 0.1 3.0 2 0 0 2 2 2 1 HHH domain Tex_YqgF PF16921.5 OEU13526.1 - 0.025 15.0 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Tex protein YqgF-like domain DASH_Spc19 PF08287.11 OEU13526.1 - 0.16 11.9 4.5 1.3 8.8 0.9 2.8 2 0 0 2 2 2 0 Spc19 Ribosomal_L9_C PF03948.14 OEU13526.1 - 0.21 12.1 1.0 1 9.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain PCRF PF03462.18 OEU13526.1 - 1.1 9.1 5.7 0.39 10.5 1.2 2.5 2 0 0 2 2 2 0 PCRF domain OTU PF02338.19 OEU13527.1 - 1.3e-05 25.7 0.0 1.8e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Metallophos PF00149.28 OEU13528.1 - 1e-38 133.9 0.2 1.4e-38 133.5 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OEU13528.1 - 0.0026 18.2 0.1 0.0071 16.8 0.1 1.7 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OEU13528.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Arc_C PF18162.1 OEU13530.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Arc C-lobe Nop14 PF04147.12 OEU13531.1 - 0.74 8.0 29.9 0.83 7.8 5.3 2.1 2 0 0 2 2 2 0 Nop14-like family FA_desaturase PF00487.24 OEU13532.1 - 9e-38 130.6 6.7 9e-38 130.6 6.7 1.3 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OEU13532.1 - 2.3e-06 27.7 0.2 5.2e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 OEU13533.1 - 2.3e-58 197.6 0.0 2.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13533.1 - 3.8e-32 111.6 0.0 4.8e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU13533.1 - 0.0002 21.4 0.0 0.00064 19.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU13533.1 - 0.12 12.0 0.1 0.3 10.7 0.1 1.7 1 1 0 1 1 1 0 RIO1 family UCH PF00443.29 OEU13534.1 - 1.6e-20 73.7 0.1 1.9e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU13534.1 - 3.6e-06 26.8 0.0 4.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IBB PF01749.20 OEU13535.1 - 0.017 15.6 1.7 0.088 13.3 0.3 2.7 2 0 0 2 2 2 0 Importin beta binding domain Arm_3 PF16186.5 OEU13535.1 - 0.13 11.8 0.4 0.36 10.4 0.4 1.7 1 0 0 1 1 1 0 Atypical Arm repeat Mucin PF01456.17 OEU13536.1 - 0.58 10.1 30.9 0.25 11.3 21.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Sigma70_r4 PF04545.16 OEU13539.1 - 1.7e-09 37.1 0.2 2.7e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 OEU13539.1 - 0.00083 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 HP1451_C PF18472.1 OEU13539.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 HP1451 C-terminal domain HMG_box PF00505.19 OEU13541.1 - 1.4e-09 38.2 2.4 5.2e-06 26.8 0.5 3.0 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU13541.1 - 2.4e-06 28.1 1.8 9.5e-05 22.9 1.8 2.7 1 1 0 1 1 1 1 HMG-box domain MlaC PF05494.12 OEU13541.1 - 0.054 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 MlaC protein DUF305 PF03713.13 OEU13542.1 - 0.12 12.5 5.2 0.33 11.1 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF305) zinc_ribbon_2 PF13240.6 OEU13542.1 - 0.12 12.1 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 OEU13542.1 - 0.13 12.3 1.7 0.3 11.2 1.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Clr2 PF10383.9 OEU13542.1 - 0.14 12.9 1.3 0.28 12.0 1.3 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 PNPase_C PF12111.8 OEU13542.1 - 0.17 11.3 2.0 0.24 10.9 0.8 1.8 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal TFIIA PF03153.13 OEU13543.1 - 7.5 6.4 32.9 4.3 7.2 21.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HMGL-like PF00682.19 OEU13544.1 - 1.5e-45 155.8 0.1 2.5e-45 155.1 0.1 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OEU13544.1 - 1.7e-20 73.3 1.5 9.1e-20 70.9 0.1 2.5 3 0 0 3 3 3 1 LeuA allosteric (dimerisation) domain zf-RING_2 PF13639.6 OEU13545.1 - 2.1e-09 37.6 7.2 2.1e-09 37.6 7.2 1.6 2 0 0 2 2 1 1 Ring finger domain CUE PF02845.16 OEU13545.1 - 3e-07 30.0 2.0 7.5e-06 25.5 0.0 3.3 4 0 0 4 4 4 1 CUE domain zf-RING_11 PF17123.5 OEU13545.1 - 4.3e-06 26.4 6.7 4.3e-06 26.4 6.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OEU13545.1 - 1.6e-05 24.8 4.8 3.2e-05 23.8 4.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OEU13545.1 - 2.3e-05 24.1 8.5 4.3e-05 23.3 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU13545.1 - 7.5e-05 22.9 7.3 0.00021 21.5 7.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OEU13545.1 - 0.00031 20.5 5.1 0.00053 19.8 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU13545.1 - 0.00067 19.4 7.9 0.0014 18.4 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU13545.1 - 0.0018 18.3 5.1 0.0066 16.5 5.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OEU13545.1 - 0.022 14.5 3.7 0.045 13.6 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 OEU13545.1 - 0.027 13.8 0.8 0.035 13.5 0.1 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger GAGA PF09237.11 OEU13545.1 - 0.034 13.9 0.1 0.034 13.9 0.1 2.0 2 0 0 2 2 2 0 GAGA factor FANCL_C PF11793.8 OEU13545.1 - 0.056 13.6 4.2 0.16 12.2 4.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OEU13545.1 - 0.068 13.0 6.4 0.15 12.0 6.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OEU13545.1 - 0.086 12.8 9.6 0.27 11.2 9.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain TFIIA PF03153.13 OEU13545.1 - 0.095 12.7 2.6 0.12 12.3 2.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Nse PF11789.8 OEU13545.1 - 0.11 12.4 2.3 0.22 11.4 2.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 OEU13545.1 - 0.15 12.0 5.2 0.29 11.0 5.2 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 OEU13545.1 - 0.29 10.8 5.2 0.8 9.4 5.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OEU13545.1 - 0.31 11.2 6.6 0.73 10.0 6.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PDZ_6 PF17820.1 OEU13546.1 - 5.2e-06 26.2 0.1 0.0016 18.2 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OEU13546.1 - 5.6e-06 26.6 0.3 0.15 12.4 0.2 2.6 2 0 0 2 2 2 2 PDZ domain PGPGW PF09656.10 OEU13546.1 - 3.8e-05 23.1 2.6 6.9e-05 22.3 2.6 1.5 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) PDZ_2 PF13180.6 OEU13546.1 - 0.00023 21.4 0.1 0.039 14.3 0.0 2.9 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 OEU13546.1 - 0.007 16.3 0.1 2 8.5 0.0 3.0 3 0 0 3 3 3 1 Tricorn protease PDZ domain CCDC32 PF14989.6 OEU13546.1 - 0.038 14.0 0.1 0.038 14.0 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing 32 CMD PF02627.20 OEU13547.1 - 0.21 11.7 0.0 0.65 10.1 0.0 1.7 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family HemN_C PF06969.16 OEU13549.1 - 0.016 15.2 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 HemN C-terminal domain AAA_assoc_C PF09821.9 OEU13549.1 - 0.028 14.9 0.0 0.043 14.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal AAA-associated domain NACHT PF05729.12 OEU13550.1 - 1.3e-07 31.7 0.1 3.1e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain CHAT PF12770.7 OEU13550.1 - 2.8e-07 30.2 0.0 6.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 CHAT domain Arm PF00514.23 OEU13550.1 - 1.7e-05 24.6 4.9 0.21 11.7 0.1 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat AAA_16 PF13191.6 OEU13550.1 - 4.7e-05 23.8 0.1 0.00026 21.4 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain LRR_6 PF13516.6 OEU13550.1 - 0.00011 22.0 14.8 0.0087 16.0 0.1 5.6 5 0 0 5 5 5 2 Leucine Rich repeat AAA_22 PF13401.6 OEU13550.1 - 0.00077 19.7 0.3 0.0027 18.0 0.3 1.9 1 0 0 1 1 1 1 AAA domain GAT PF03127.14 OEU13550.1 - 0.0056 17.0 0.5 0.034 14.5 0.2 2.5 2 0 0 2 2 2 1 GAT domain DUF454 PF04304.13 OEU13550.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF454) LRR_1 PF00560.33 OEU13550.1 - 1.6 9.5 10.8 89 4.3 0.0 5.5 4 1 0 4 4 4 0 Leucine Rich Repeat ACT_6 PF13740.6 OEU13551.1 - 3.3e-16 59.0 0.1 4.8e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 ACT domain Mpv17_PMP22 PF04117.12 OEU13551.1 - 5.8e-13 48.9 0.1 1.2e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family ACT_4 PF13291.6 OEU13551.1 - 5.3e-10 39.8 0.2 0.0014 19.2 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 OEU13551.1 - 1.1e-07 31.4 0.2 0.0012 18.5 0.1 2.5 2 0 0 2 2 2 2 ACT domain DUF1406 PF07190.11 OEU13551.1 - 0.061 13.3 0.1 6.9 6.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1406) NAD_binding_10 PF13460.6 OEU13553.1 - 4e-11 43.1 0.0 4.9e-09 36.3 0.0 2.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OEU13553.1 - 0.0033 16.9 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 OEU13553.1 - 0.042 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OEU13553.1 - 0.059 13.6 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OEU13553.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 OEU13553.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S7 PF00177.21 OEU13554.1 - 6.2e-35 120.0 0.4 8.1e-35 119.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3336 PF11815.8 OEU13555.1 - 4.2e-25 88.1 2.7 6.3e-25 87.5 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OEU13555.1 - 3.8e-17 63.1 0.0 6.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Orthopox_A5L PF06193.11 OEU13555.1 - 0.14 11.6 0.4 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Na_Pi_cotrans PF02690.15 OEU13556.1 - 2.9e-41 140.8 34.0 3.8e-23 82.1 7.4 2.8 2 1 0 2 2 2 2 Na+/Pi-cotransporter DUF2649 PF10854.8 OEU13556.1 - 4.9 7.5 8.0 19 5.6 1.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2649) Jagunal PF07086.12 OEU13556.1 - 5 7.2 11.1 0.87 9.6 0.5 3.4 3 0 0 3 3 3 0 Jagunal, ER re-organisation during oogenesis Rer1 PF03248.13 OEU13556.1 - 9.3 6.0 8.9 38 4.0 0.0 3.5 4 0 0 4 4 4 0 Rer1 family Rad60-SLD PF11976.8 OEU13557.1 - 2.4e-06 27.3 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OEU13557.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family SET PF00856.28 OEU13558.1 - 8.5e-06 26.3 0.1 2.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 SET domain PDZ_5 PF17817.1 OEU13558.1 - 0.011 16.0 0.1 0.031 14.6 0.1 1.7 1 0 0 1 1 1 0 PDZ domain MecA PF05389.12 OEU13558.1 - 0.091 12.4 2.4 0.19 11.3 2.4 1.5 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Med15 PF09606.10 OEU13559.1 - 0.0089 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_pol_E_B PF04042.16 OEU13560.1 - 2.1e-37 128.5 0.1 2.4e-37 128.3 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_3 PF14582.6 OEU13560.1 - 0.044 13.1 0.2 7.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Pox_EPC_I2-L1 PF12575.8 OEU13560.1 - 0.19 12.0 0.1 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF1517 PF07466.11 OEU13561.1 - 8.1e-33 114.1 0.7 1.1e-32 113.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) PT PF04886.12 OEU13562.1 - 5e-15 54.8 55.7 1.7e+04 -4.5 55.7 3.8 1 1 0 1 1 1 0 PT repeat PT PF04886.12 OEU13563.1 - 5.5e-13 48.2 53.1 4.2e-05 23.0 26.2 2.9 1 1 1 2 2 2 2 PT repeat Glycoprotein_G PF00802.19 OEU13563.1 - 0.52 9.6 14.1 0.6 9.4 14.1 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Trypsin PF00089.26 OEU13564.1 - 2e-48 165.1 0.0 2.2e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin SCAI PF12070.8 OEU13565.1 - 0.22 10.4 1.6 0.35 9.7 1.6 1.2 1 0 0 1 1 1 0 Protein SCAI DUF2681 PF10883.8 OEU13565.1 - 3.4 8.1 8.1 8 6.9 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Pterin_bind PF00809.22 OEU13566.1 - 5e-71 239.2 0.2 5.8e-71 239.0 0.2 1.0 1 0 0 1 1 1 1 Pterin binding enzyme PEP_mutase PF13714.6 OEU13566.1 - 0.0041 16.6 0.7 0.086 12.3 0.1 2.1 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Sacchrp_dh_NADP PF03435.18 OEU13566.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAM60A PF15396.6 OEU13567.1 - 7.3 6.5 9.9 0.39 10.7 2.8 2.4 2 1 0 2 2 2 0 Protein Family FAM60A Arrestin_N PF00339.29 OEU13568.1 - 3.2e-06 27.3 0.6 4.3e-05 23.6 0.1 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain DUF4633 PF15464.6 OEU13568.1 - 0.041 14.0 0.1 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) DUF3678 PF12435.8 OEU13568.1 - 4.4 6.8 5.7 29 4.2 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DnaJ PF00226.31 OEU13569.1 - 2.5e-16 59.6 0.0 2.6e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain E1-E2_ATPase PF00122.20 OEU13570.1 - 8.9e-45 152.4 1.4 8.9e-45 152.4 1.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OEU13570.1 - 1.9e-32 113.3 0.0 4.1e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OEU13570.1 - 1.5e-07 31.4 0.1 0.0085 15.9 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU13570.1 - 6.1e-07 30.0 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OEU13570.1 - 0.0016 18.8 0.4 0.026 15.0 0.0 2.8 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_6 PF13344.6 OEU13570.1 - 0.074 13.2 0.0 0.97 9.6 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Aa_trans PF01490.18 OEU13571.1 - 7.1e-20 71.1 7.7 1.4e-18 66.8 5.0 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein ABC_tran PF00005.27 OEU13572.1 - 2.8e-30 105.6 0.0 5.1e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OEU13572.1 - 2.3e-27 96.4 1.9 3e-27 96.0 1.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OEU13572.1 - 5.6e-05 22.7 0.1 0.00082 18.9 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OEU13572.1 - 0.0058 16.5 0.3 0.085 12.8 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 OEU13572.1 - 0.011 15.5 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OEU13572.1 - 0.017 15.6 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OEU13572.1 - 0.02 15.0 0.0 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OEU13572.1 - 0.023 14.9 0.7 0.15 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OEU13572.1 - 0.034 14.5 0.1 0.072 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OEU13572.1 - 0.035 13.8 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OEU13572.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 OEU13572.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 OEU13572.1 - 0.1 12.3 0.0 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 OEU13572.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Gp_dh_C PF02800.20 OEU13573.1 - 1e-63 213.6 0.0 1.5e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU13573.1 - 1.6e-37 127.9 0.0 4.8e-37 126.4 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OEU13573.1 - 0.038 14.1 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Chloroa_b-bind PF00504.21 OEU13574.1 - 9.8e-27 94.5 0.1 1.3e-26 94.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein WW PF00397.26 OEU13575.1 - 3.6e-21 74.9 14.9 2.7e-12 46.5 2.1 3.0 2 1 0 2 2 2 2 WW domain Tachylectin PF14517.6 OEU13575.1 - 0.0052 16.4 0.9 0.0083 15.7 0.9 1.4 1 0 0 1 1 1 1 Tachylectin DUF2956 PF11169.8 OEU13575.1 - 0.017 15.3 0.4 0.017 15.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Neur_chan_memb PF02932.16 OEU13575.1 - 0.026 14.6 0.7 0.026 14.6 0.7 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L13 PF00572.18 OEU13576.1 - 1.7e-54 183.4 0.1 2e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3848 PF12959.7 OEU13576.1 - 0.086 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) GHMP_kinases_C PF08544.13 OEU13577.1 - 2.5e-12 47.0 0.1 6.5e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OEU13577.1 - 2.2e-08 34.2 0.5 6.2e-08 32.8 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ntox34 PF15606.6 OEU13577.1 - 0.019 15.1 1.1 0.18 12.0 0.2 2.7 2 1 1 3 3 3 0 Bacterial toxin 34 HEAT_2 PF13646.6 OEU13579.1 - 0.0055 17.1 0.0 0.26 11.7 0.0 3.2 2 1 0 2 2 2 1 HEAT repeats RIX1 PF08167.12 OEU13579.1 - 0.01 15.6 1.9 0.12 12.1 0.1 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.8 OEU13579.1 - 0.05 13.7 0.5 9.3 6.4 0.1 3.0 2 0 0 2 2 2 0 V-ATPase subunit H HEAT PF02985.22 OEU13579.1 - 0.14 12.5 3.0 1.8 9.0 0.3 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 OEU13579.1 - 0.23 12.0 4.8 1.3 9.6 0.3 4.2 5 1 0 5 5 5 0 HEAT-like repeat zf-MYND PF01753.18 OEU13580.1 - 5.6e-08 32.7 17.5 9.4e-08 32.0 17.5 1.3 1 0 0 1 1 1 1 MYND finger Methyltr_RsmB-F PF01189.17 OEU13582.1 - 8.3e-37 126.8 0.0 2.2e-36 125.4 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DAO PF01266.24 OEU13584.1 - 1.7e-41 143.0 0.0 2.4e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OEU13584.1 - 1.6e-40 137.8 0.0 4.7e-40 136.4 0.0 1.8 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 OEU13584.1 - 4.3e-10 39.9 0.9 1e-09 38.7 0.9 1.6 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 OEU13584.1 - 9.2e-09 34.9 0.0 2.4e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain EF-hand_1 PF00036.32 OEU13584.1 - 5.3e-07 28.7 3.3 0.0047 16.4 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU13584.1 - 1.8e-06 27.4 0.5 0.0086 15.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU13584.1 - 6.7e-05 22.7 1.3 0.00096 19.0 0.2 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU13584.1 - 0.00011 21.5 4.3 0.0022 17.4 0.4 2.5 2 0 0 2 2 2 1 EF hand Pyr_redox_2 PF07992.14 OEU13584.1 - 0.00018 20.9 0.0 0.0071 15.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU13584.1 - 0.00063 19.1 0.2 0.088 12.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain SPARC_Ca_bdg PF10591.9 OEU13584.1 - 0.0095 16.2 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region HHH_4 PF14490.6 OEU13584.1 - 0.038 14.0 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain ADSL_C PF10397.9 OEU13584.1 - 0.039 14.5 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus FAD_oxidored PF12831.7 OEU13584.1 - 0.042 13.2 2.6 0.094 12.0 2.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OEU13584.1 - 0.049 12.9 0.6 0.27 10.5 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU13584.1 - 0.094 11.4 0.3 0.16 10.7 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OEU13584.1 - 0.25 10.4 1.8 0.58 9.2 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Radical_SAM PF04055.21 OEU13586.1 - 2.4e-21 76.8 0.0 5.4e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 OEU13586.1 - 5.3e-16 58.5 0.0 1.4e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM_2 PF18693.1 OEU13586.1 - 1e-10 41.6 0.1 2.5e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 TRAM domain DUF4252 PF14060.6 OEU13586.1 - 0.076 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) PRIMA1 PF16101.5 OEU13587.1 - 0.13 12.3 12.6 0.39 10.8 12.6 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EGF_2 PF07974.13 OEU13588.1 - 0.00026 21.3 0.6 0.00026 21.3 0.6 4.0 3 2 0 3 3 3 1 EGF-like domain DSL PF01414.19 OEU13588.1 - 0.086 13.1 5.3 0.64 10.3 1.1 2.8 2 0 0 2 2 2 0 Delta serrate ligand EGF PF00008.27 OEU13588.1 - 0.74 10.2 21.4 6.4 7.2 1.1 4.4 3 1 0 3 3 3 0 EGF-like domain RrnaAD PF00398.20 OEU13590.1 - 1.9e-60 204.2 0.2 2.5e-60 203.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OEU13590.1 - 3.2e-07 31.0 0.0 6.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU13590.1 - 4.1e-05 24.1 0.0 9.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OEU13590.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OEU13590.1 - 0.00025 20.5 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 OEU13590.1 - 0.0073 17.0 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU13590.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OEU13590.1 - 0.034 13.7 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 OEU13590.1 - 0.059 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 OEU13590.1 - 0.065 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 OEU13590.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 OEU13590.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Occludin_ELL PF07303.13 OEU13590.1 - 0.84 10.4 3.0 0.36 11.6 0.6 1.6 2 0 0 2 2 1 0 Occludin homology domain DUF1764 PF08576.10 OEU13591.1 - 1.2e-12 48.5 6.9 1.2e-12 48.5 6.9 2.1 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Ribosomal_L14 PF00238.19 OEU13592.1 - 3.5e-34 117.5 0.1 4.2e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Polo_box_3 PF18544.1 OEU13593.1 - 0.043 14.4 1.9 0.8 10.4 0.1 2.9 3 0 0 3 3 3 0 Polo box domain Calreticulin PF00262.18 OEU13595.1 - 4.1e-84 282.5 14.2 5.1e-63 213.1 4.4 2.2 1 1 1 2 2 2 2 Calreticulin family DUF3844 PF12955.7 OEU13596.1 - 4.3 7.5 5.5 19 5.4 1.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3844) PRIMA1 PF16101.5 OEU13596.1 - 6.9 6.7 16.6 19 5.3 1.0 3.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PMSR PF01625.21 OEU13597.1 - 3.9e-08 33.6 0.0 5.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PPR_2 PF13041.6 OEU13598.1 - 5e-09 36.2 0.1 0.00093 19.3 0.3 5.8 7 1 1 8 8 8 3 PPR repeat family PPR_1 PF12854.7 OEU13598.1 - 6.2e-05 22.6 0.0 9.1 6.1 0.0 5.3 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 OEU13598.1 - 0.00012 22.1 0.0 9.8 6.3 0.0 6.0 5 2 1 6 6 6 1 Pentatricopeptide repeat domain SET PF00856.28 OEU13599.1 - 4e-14 53.4 0.1 4.8e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 SET domain bVLRF1 PF18826.1 OEU13601.1 - 3.8e-35 121.0 3.7 3.6e-34 117.8 0.0 2.4 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor VATC PF18716.1 OEU13601.1 - 1.6e-07 31.1 2.7 1.6e-07 31.1 2.7 1.7 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank PF00023.30 OEU13601.1 - 0.0033 17.8 3.0 0.0041 17.5 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OEU13601.1 - 0.019 15.4 0.1 7.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat SDA1 PF05285.12 OEU13601.1 - 0.27 10.6 35.5 0.28 10.6 18.7 2.5 2 0 0 2 2 2 0 SDA1 zf-FCS PF06467.14 OEU13601.1 - 0.29 11.1 4.4 0.64 10.0 4.4 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif CDC45 PF02724.14 OEU13601.1 - 0.53 8.5 23.1 0.16 10.2 8.2 2.4 2 0 0 2 2 2 0 CDC45-like protein eIF3_subunit PF08597.10 OEU13601.1 - 7.2 6.4 33.0 5.2 6.9 15.3 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SAPS PF04499.15 OEU13601.1 - 7.4 5.2 19.6 4.8 5.9 1.6 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein 2Fe-2S_thioredx PF01257.19 OEU13602.1 - 0.0078 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Methyltransf_16 PF10294.9 OEU13604.1 - 5e-27 94.7 0.0 8.4e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ank_2 PF12796.7 OEU13604.1 - 1.6e-15 57.5 0.0 3.7e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU13604.1 - 2.2e-11 44.0 0.1 0.00087 19.8 0.0 3.5 4 0 0 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU13604.1 - 8.4e-11 41.1 0.1 0.024 15.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OEU13604.1 - 1.2e-09 38.2 0.1 0.0021 18.4 0.2 3.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OEU13604.1 - 1.2e-07 31.9 1.0 0.016 15.5 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Met_10 PF02475.16 OEU13604.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 OEU13604.1 - 3.1e-05 23.5 0.0 9.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU13604.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OEU13604.1 - 6.8e-05 22.8 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU13604.1 - 0.00052 20.7 0.0 0.0013 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU13604.1 - 0.0023 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU13604.1 - 0.011 16.4 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OEU13604.1 - 0.013 16.3 0.0 0.031 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 OEU13604.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase GidB PF02527.15 OEU13604.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HTH_Tnp_IS1 PF12759.7 OEU13605.1 - 0.0053 16.3 0.4 18 5.1 0.0 4.0 5 0 0 5 5 5 2 InsA C-terminal domain DUF874 PF05917.11 OEU13605.1 - 0.13 11.3 33.5 0.17 10.9 10.4 2.6 1 1 1 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) BIR PF00653.21 OEU13605.1 - 0.22 12.2 9.6 36 5.1 0.2 4.4 1 1 3 4 4 4 0 Inhibitor of Apoptosis domain PDZ PF00595.24 OEU13606.1 - 1.6e-05 25.2 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU13606.1 - 0.00034 20.4 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU13606.1 - 0.0035 17.6 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LRR_4 PF12799.7 OEU13607.1 - 1.4e-12 47.6 1.1 2.8e-05 24.4 0.0 5.1 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13607.1 - 1.5e-10 40.7 10.0 0.00027 20.7 2.9 3.9 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 OEU13607.1 - 0.00021 21.4 6.4 7.4 7.5 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 OEU13607.1 - 0.0026 17.3 0.0 0.008 15.7 0.0 1.8 2 0 0 2 2 2 1 Leucine-rich repeat PD40 PF07676.12 OEU13608.1 - 0.023 14.6 0.1 15 5.6 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat C2 PF00168.30 OEU13610.1 - 1.2e-05 25.6 0.0 0.67 10.3 0.0 3.7 3 0 0 3 3 3 2 C2 domain PRT_C PF08372.10 OEU13610.1 - 0.00011 22.0 0.8 0.29 10.9 0.1 2.4 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal C1_1 PF00130.22 OEU13610.1 - 0.015 15.2 6.0 0.027 14.4 6.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pex24p PF06398.11 OEU13610.1 - 0.017 14.1 0.1 0.82 8.6 0.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Reticulon PF02453.17 OEU13610.1 - 0.021 14.8 0.5 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Reticulon DUF639 PF04842.12 OEU13610.1 - 0.052 12.9 0.2 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) C1_2 PF03107.16 OEU13610.1 - 0.44 10.9 7.0 1.1 9.6 7.0 1.7 1 0 0 1 1 1 0 C1 domain zf-RING_2 PF13639.6 OEU13611.1 - 8.2e-12 45.3 5.8 1.3e-11 44.6 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU13611.1 - 1.2e-08 34.6 6.6 2.4e-08 33.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU13611.1 - 5.6e-08 32.6 3.2 9.8e-08 31.8 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OEU13611.1 - 1.2e-07 31.4 3.1 1.2e-07 31.4 3.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU13611.1 - 1.7e-07 31.4 7.7 5.3e-07 29.8 7.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OEU13611.1 - 6.2e-07 29.2 4.4 1.2e-06 28.3 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OEU13611.1 - 8.4e-07 28.8 6.5 1.9e-06 27.7 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU13611.1 - 8.8e-07 28.8 2.6 1.5e-06 28.1 0.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU13611.1 - 1.6e-05 24.7 7.4 2.7e-05 23.9 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU13611.1 - 7.2e-05 22.8 2.7 0.00012 22.0 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OEU13611.1 - 0.00032 20.3 6.7 0.00057 19.4 6.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OEU13611.1 - 0.0031 17.6 3.1 0.0067 16.5 3.1 1.6 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 OEU13611.1 - 0.014 15.5 8.5 0.091 13.0 8.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OEU13611.1 - 0.039 13.8 3.8 0.082 12.7 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.11 OEU13611.1 - 2.5 8.1 5.0 5.7 6.9 5.0 1.6 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF948 PF06103.11 OEU13612.1 - 0.0043 17.3 3.1 11 6.4 0.0 3.6 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) ASFV_360 PF01671.16 OEU13612.1 - 0.08 12.4 3.0 0.62 9.5 0.3 2.3 2 0 0 2 2 2 0 African swine fever virus multigene family 360 protein ApoLp-III PF07464.11 OEU13612.1 - 0.11 12.6 4.8 0.65 10.1 0.2 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) HPIH PF13323.6 OEU13612.1 - 0.21 11.4 1.7 0.52 10.2 0.0 2.4 3 0 0 3 3 3 0 N-terminal domain with HPIH motif HR1 PF02185.16 OEU13612.1 - 3.2 7.9 5.7 0.37 10.9 0.8 1.9 2 0 0 2 2 2 0 Hr1 repeat Mod_r PF07200.13 OEU13612.1 - 4.1 7.5 7.7 2.3 8.3 0.3 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein O-FucT PF10250.9 OEU13613.1 - 0.0041 16.9 5.5 0.84 9.3 0.0 2.9 3 1 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase DnaJ-X PF14308.6 OEU13614.1 - 5.2e-22 78.3 4.7 1.3e-13 50.8 2.1 2.8 1 1 2 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.31 OEU13614.1 - 8.9e-22 77.0 1.8 2e-21 75.9 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 OEU13615.1 - 0.1 13.5 1.2 30 5.7 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat SET PF00856.28 OEU13616.1 - 8.8e-07 29.5 0.0 7.2e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 SET domain PPR_2 PF13041.6 OEU13617.1 - 1.3e-16 60.5 0.0 0.0077 16.4 0.0 7.8 8 1 0 8 8 8 5 PPR repeat family PPR_1 PF12854.7 OEU13617.1 - 1.3e-13 50.4 0.0 0.091 12.5 0.0 7.7 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.6 OEU13617.1 - 5.3e-11 42.4 0.0 0.1 12.7 0.0 5.4 4 2 2 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 OEU13617.1 - 1.4e-08 34.4 8.0 0.6 10.5 0.0 8.7 9 0 0 9 9 9 2 PPR repeat ATP13 PF12921.7 OEU13617.1 - 1e-05 25.4 2.8 0.66 9.9 0.1 4.1 3 1 1 4 4 4 2 Mitochondrial ATPase expression PPR_long PF17177.4 OEU13617.1 - 0.001 18.5 0.4 3.1 7.1 0.0 3.5 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP Peptidase_M50 PF02163.22 OEU13618.1 - 8.6e-05 21.9 13.2 0.0036 16.6 1.8 2.7 1 1 2 3 3 3 2 Peptidase family M50 RNB PF00773.19 OEU13619.1 - 1.5e-55 188.8 0.0 1.4e-54 185.6 0.0 2.2 1 1 0 1 1 1 1 RNB domain WD40 PF00400.32 OEU13620.1 - 3.5e-12 46.6 11.2 0.00046 20.9 0.3 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OEU13620.1 - 0.15 11.0 0.1 4.4 6.2 0.0 2.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2285 PF10074.9 OEU13621.1 - 2.7 8.7 5.5 43 4.8 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) DUF5575 PF17738.1 OEU13624.1 - 0.0055 15.8 0.1 0.0073 15.4 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5575) Syntaxin-6_N PF09177.11 OEU13624.1 - 0.0088 16.6 1.6 0.024 15.2 1.6 1.6 1 0 0 1 1 1 1 Syntaxin 6, N-terminal DUF4825 PF16107.5 OEU13624.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) SSB PF00436.25 OEU13625.1 - 2.3e-10 40.4 0.0 4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Single-strand binding protein family PT PF04886.12 OEU13626.1 - 7e-09 35.1 43.7 7.1e-05 22.3 11.4 3.5 3 0 0 3 3 3 3 PT repeat Rol_Rep_N PF18106.1 OEU13627.1 - 0.00087 19.6 0.9 0.049 14.0 0.1 2.2 2 0 0 2 2 2 2 Rolling Circle replication initiation protein N-terminal domain Neur_chan_memb PF02932.16 OEU13627.1 - 8 6.4 8.8 12 5.8 0.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CBFD_NFYB_HMF PF00808.23 OEU13628.1 - 4.1e-14 52.6 1.4 7.6e-10 38.9 0.1 2.5 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU13628.1 - 4.2e-09 36.8 0.7 4.2e-09 36.8 0.7 2.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 INSIG PF07281.12 OEU13629.1 - 8.4e-05 22.3 0.2 0.00021 21.0 0.1 1.7 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DnaJ_CXXCXGXG PF00684.19 OEU13629.1 - 0.3 11.5 15.4 1.3 9.4 15.4 2.0 1 1 0 1 1 1 0 DnaJ central domain Anti-TRAP PF15777.5 OEU13629.1 - 7.4 6.6 8.9 1.2 9.2 3.5 2.1 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein FAD_binding_3 PF01494.19 OEU13631.1 - 1.7e-19 70.3 3.0 1.7e-09 37.4 0.0 3.7 3 1 1 4 4 4 3 FAD binding domain DAO PF01266.24 OEU13631.1 - 2.7e-07 30.5 0.3 4.3e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU13631.1 - 6.5e-05 22.2 1.7 0.00012 21.3 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OEU13631.1 - 0.00092 19.4 0.2 0.0022 18.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU13631.1 - 0.0018 17.6 0.0 0.0035 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU13631.1 - 0.0074 15.6 1.8 0.0074 15.6 1.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SPT6_acidic PF14632.6 OEU13631.1 - 0.019 15.5 2.5 0.019 15.5 2.5 3.5 4 0 0 4 4 4 0 Acidic N-terminal SPT6 Thi4 PF01946.17 OEU13631.1 - 0.023 14.0 0.7 0.048 12.9 0.7 1.5 1 0 0 1 1 1 0 Thi4 family DUF3446 PF11928.8 OEU13631.1 - 0.39 11.1 17.1 0.25 11.7 6.4 3.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Lycopene_cycl PF05834.12 OEU13631.1 - 0.81 8.7 2.2 0.75 8.8 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein CENP-B_dimeris PF09026.10 OEU13631.1 - 1.2 9.6 7.3 1.3 9.5 0.1 3.7 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Pirin PF02678.16 OEU13632.1 - 4.4e-22 78.1 0.7 1.5e-21 76.4 0.4 1.9 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 OEU13632.1 - 3.7e-16 59.4 0.0 8.1e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain UreE_N PF02814.15 OEU13632.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Pkinase PF00069.25 OEU13633.1 - 4.5e-76 255.7 0.0 5.5e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13633.1 - 5.8e-38 130.6 0.0 7.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU13633.1 - 2.7e-05 23.6 0.0 5.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 OEU13634.1 - 6.5e-19 68.7 0.0 7.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2OG-FeII_Oxy_3 PF13640.6 OEU13635.1 - 3.3e-11 43.9 0.0 8.1e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU13635.1 - 0.0073 16.8 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amino_oxidase PF01593.24 OEU13636.1 - 3e-24 86.1 0.0 1.9e-19 70.3 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU13636.1 - 6.2e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU13636.1 - 0.026 14.5 0.0 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Hormone_2 PF00123.20 OEU13637.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptide hormone MID_MedPIWI PF18296.1 OEU13637.1 - 0.086 12.6 2.1 0.088 12.6 2.1 1.1 1 0 0 1 1 1 0 MID domain of medPIWI DNA_pol_phi PF04931.13 OEU13637.1 - 0.14 10.2 7.4 0.17 10.0 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cullin PF00888.22 OEU13639.1 - 1.8e-162 542.1 5.1 2.5e-162 541.7 5.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OEU13639.1 - 2.2e-25 88.5 2.2 3.7e-25 87.7 0.7 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Sgf11_N PF18519.1 OEU13639.1 - 0.39 10.3 0.1 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain APOBEC4_like PF18774.1 OEU13640.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase HMG_box PF00505.19 OEU13641.1 - 1.1e-25 89.8 3.8 1.9e-16 60.2 0.1 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU13641.1 - 2e-15 57.1 3.9 4.7e-07 30.3 0.8 2.2 2 0 0 2 2 2 2 HMG-box domain Sec20 PF03908.13 OEU13643.1 - 2e-07 30.8 4.0 2.1e-06 27.6 0.1 2.5 2 1 1 3 3 3 1 Sec20 V-SNARE_C PF12352.8 OEU13643.1 - 3.3e-07 30.5 0.7 3.3e-07 30.5 0.7 2.1 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 OEU13643.1 - 7.5e-06 26.2 3.0 7.5e-06 26.2 3.0 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF4407 PF14362.6 OEU13643.1 - 0.0012 18.3 2.7 0.0015 17.9 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) RPW8 PF05659.11 OEU13643.1 - 0.0024 17.6 3.4 0.032 13.9 0.6 2.2 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5089 PF17002.5 OEU13643.1 - 0.0051 16.7 1.3 0.0051 16.7 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) Prominin PF05478.11 OEU13643.1 - 0.0056 14.7 0.2 0.063 11.2 0.0 1.9 2 0 0 2 2 2 1 Prominin Syntaxin-6_N PF09177.11 OEU13643.1 - 0.017 15.6 4.7 0.33 11.6 1.6 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal EMP24_GP25L PF01105.24 OEU13643.1 - 0.025 14.5 2.4 3.3 7.6 0.4 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Val_tRNA-synt_C PF10458.9 OEU13643.1 - 0.084 13.2 2.5 0.48 10.7 0.0 2.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2408 PF10303.9 OEU13643.1 - 0.17 12.4 4.2 1.6 9.3 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) WXG100 PF06013.12 OEU13643.1 - 0.82 9.9 7.0 7.2 6.9 1.3 3.2 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Synaptobrevin PF00957.21 OEU13643.1 - 1.4 8.8 5.1 7.9 6.4 2.5 2.5 2 1 0 2 2 2 0 Synaptobrevin Allexi_40kDa PF05549.11 OEU13643.1 - 2.4 7.6 4.3 2.4 7.6 1.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein Sec2p PF06428.11 OEU13643.1 - 4.9 7.2 11.5 10 6.1 1.7 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p GrpE PF01025.19 OEU13643.1 - 5.3 6.7 9.4 2.1 8.0 0.6 2.4 2 1 0 2 2 2 0 GrpE Mis14 PF08641.12 OEU13643.1 - 8.3 6.7 9.1 5.5 7.3 0.7 2.9 1 1 2 3 3 3 0 Kinetochore protein Mis14 like GDC-P PF02347.16 OEU13644.1 - 1.5e-181 603.9 0.0 4.6e-169 562.8 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 OEU13644.1 - 0.0001 21.4 1.0 0.00019 20.5 0.2 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OEU13644.1 - 0.00024 20.5 0.1 0.00052 19.4 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase UPF0253 PF06786.12 OEU13644.1 - 0.061 13.6 0.0 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Cation_ATPase_N PF00690.26 OEU13644.1 - 0.16 11.7 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Kinesin PF00225.23 OEU13646.1 - 3.2e-102 341.9 1.9 3.8e-102 341.6 1.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU13646.1 - 5.9e-21 75.0 0.3 2e-20 73.3 0.1 2.0 2 1 0 2 2 2 1 Microtubule binding PP2C PF00481.21 OEU13647.1 - 2.6e-41 142.0 0.1 2.9e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU13647.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C DUF241 PF03087.14 OEU13649.1 - 0.0064 16.4 0.3 0.021 14.7 0.3 1.9 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Topoisom_I_N PF02919.15 OEU13649.1 - 3.8 6.9 7.5 0.78 9.2 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4366 PF14283.6 OEU13650.1 - 0.04 14.0 0.4 0.043 13.9 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIG-I_C-RD PF11648.8 OEU13650.1 - 0.13 12.5 1.4 0.15 12.3 0.8 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I FAM165 PF14981.6 OEU13650.1 - 0.16 11.8 5.8 0.14 12.0 2.8 2.0 2 0 0 2 2 2 0 FAM165 family PPR_2 PF13041.6 OEU13651.1 - 7.2e-14 51.7 8.3 9e-06 25.8 0.3 6.5 4 3 3 7 7 7 3 PPR repeat family PPR_3 PF13812.6 OEU13651.1 - 1.2e-10 41.3 4.5 0.0042 17.1 0.1 6.3 5 1 2 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU13651.1 - 2.5e-08 33.5 11.9 0.013 15.2 0.0 7.0 9 0 0 9 9 9 3 PPR repeat ATP13 PF12921.7 OEU13651.1 - 0.003 17.4 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR PF01535.20 OEU13651.1 - 0.0058 16.8 22.6 0.042 14.1 0.1 9.0 10 1 0 10 10 10 1 PPR repeat TC1 PF15063.6 OEU13651.1 - 0.028 14.3 0.1 14 5.7 0.0 3.5 4 0 0 4 4 4 0 Thyroid cancer protein 1 RPM2 PF08579.11 OEU13651.1 - 0.039 14.4 1.4 1.5 9.3 0.1 3.3 2 2 2 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) DegV PF02645.16 OEU13651.1 - 0.065 12.6 0.6 0.14 11.4 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 TLD PF07534.16 OEU13653.1 - 2.5e-22 79.6 0.0 4.5e-22 78.8 0.0 1.4 1 1 0 1 1 1 1 TLD PAP_fibrillin PF04755.12 OEU13654.1 - 4.7e-22 78.9 2.2 8.7e-19 68.2 2.2 2.7 1 1 0 1 1 1 1 PAP_fibrillin Phage_G PF02306.15 OEU13654.1 - 0.1 12.3 0.1 0.25 11.0 0.1 1.7 1 1 1 2 2 2 0 Major spike protein (G protein) SNAP PF14938.6 OEU13656.1 - 3.4e-06 26.7 0.1 3.4e-06 26.7 0.1 2.7 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP DUF3446 PF11928.8 OEU13656.1 - 0.023 15.0 4.3 0.062 13.6 4.3 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF4820 PF16091.5 OEU13656.1 - 0.36 10.2 4.3 0.63 9.4 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ALMT PF11744.8 OEU13656.1 - 0.67 8.7 4.5 1.1 8.0 4.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GDA1_CD39 PF01150.17 OEU13657.1 - 1.1e-66 225.3 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SNARE_assoc PF09335.11 OEU13657.1 - 0.046 14.2 0.2 0.092 13.2 0.2 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF3789 PF12664.7 OEU13657.1 - 0.11 12.2 0.2 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) ResIII PF04851.15 OEU13659.1 - 8.6e-16 58.4 0.2 7.7e-15 55.3 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU13659.1 - 1.7e-14 54.1 0.0 6.4e-14 52.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU13659.1 - 4e-14 52.8 0.0 2.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Glycos_transf_1 PF00534.20 OEU13659.1 - 7.3e-07 28.9 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU13659.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Tn7_TnsC_Int PF11426.8 OEU13661.1 - 0.009 16.2 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 Tn7 transposition regulator TnsC WD40 PF00400.32 OEU13663.1 - 0.00076 20.2 0.3 0.3 12.1 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU13663.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L10 PF00466.20 OEU13664.1 - 2.3e-19 69.3 0.2 4.2e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 P34-Arc PF04045.14 OEU13665.1 - 1.4e-23 83.8 0.0 2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc GNT-I PF03071.15 OEU13666.1 - 9.8e-92 308.0 0.0 1.2e-91 307.7 0.0 1.0 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 OEU13666.1 - 0.00097 18.3 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Glyco_hydro_47 PF01532.20 OEU13667.1 - 2.5e-87 293.7 0.0 1.1e-86 291.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 K_channel_TID PF07941.11 OEU13669.1 - 0.3 11.6 1.8 4 8.0 0.1 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Fasciclin PF02469.22 OEU13670.1 - 7.1e-16 58.6 0.0 1.1e-07 32.2 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain IGPS PF00218.21 OEU13672.1 - 3.9e-21 75.4 0.0 4.3e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NIBRIN_BRCT_II PF16508.5 OEU13673.1 - 0.045 14.1 5.3 0.39 11.0 0.5 2.7 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein zf-ZPR1 PF03367.13 OEU13673.1 - 0.29 11.0 3.1 0.21 11.4 0.5 2.1 2 0 0 2 2 2 0 ZPR1 zinc-finger domain S1-P1_nuclease PF02265.16 OEU13676.1 - 5e-42 144.5 0.9 1.5e-40 139.6 0.9 2.5 1 1 0 1 1 1 1 S1/P1 Nuclease DUF4879 PF16219.5 OEU13676.1 - 0.54 10.5 3.5 1 9.6 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4879) MRP-L46 PF11788.8 OEU13678.1 - 3.4e-06 27.8 0.6 7.6e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 DUF4214 PF13946.6 OEU13678.1 - 0.097 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) FixH PF05751.11 OEU13678.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 FixH HBD PF18534.1 OEU13679.1 - 0.042 14.0 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Helical bundle domain DUF4142 PF13628.6 OEU13679.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) NDUF_B7 PF05676.13 OEU13680.1 - 1.3e-21 76.0 6.1 1.5e-21 75.9 6.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ATP-synt_D PF01813.17 OEU13681.1 - 1.8e-58 197.7 1.6 2.4e-58 197.2 1.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF5446 PF17522.2 OEU13681.1 - 0.033 14.4 0.6 0.071 13.3 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF1451 PF07295.11 OEU13681.1 - 0.96 9.5 4.2 0.82 9.7 0.7 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF1272 PF06906.11 OEU13682.1 - 0.00082 19.4 14.9 0.00099 19.1 13.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) zf-RING_5 PF14634.6 OEU13682.1 - 0.012 15.5 16.5 0.028 14.4 16.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Angiomotin_C PF12240.8 OEU13682.1 - 0.032 13.8 7.6 0.13 11.8 2.9 2.4 1 1 1 2 2 2 0 Angiomotin C terminal Sec2p PF06428.11 OEU13682.1 - 0.05 13.6 4.0 0.12 12.4 4.0 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p zf-RING_7 PF02591.15 OEU13682.1 - 0.065 13.4 0.3 0.065 13.4 0.3 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain V_ATPase_I PF01496.19 OEU13682.1 - 0.32 8.9 4.1 0.4 8.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4_3 PF13920.6 OEU13682.1 - 0.42 10.5 17.5 0.94 9.4 16.1 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OEU13682.1 - 1.8 8.4 15.6 4 7.3 15.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OEU13682.1 - 3.4 8.1 17.2 8.2 6.9 17.2 1.7 1 0 0 1 1 1 0 Ring finger domain ABC2_membrane PF01061.24 OEU13683.1 - 1.7e-30 106.0 1.2 2.6e-30 105.4 1.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OEU13683.1 - 6.8e-25 88.2 0.0 1.7e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU13683.1 - 3.7e-05 23.7 0.0 0.025 14.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OEU13683.1 - 7.4e-05 23.2 0.4 0.00017 22.0 0.1 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU13683.1 - 0.00025 21.3 0.0 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OEU13683.1 - 0.0007 20.0 0.1 0.013 16.0 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 OEU13683.1 - 0.001 18.6 0.1 0.0042 16.5 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 OEU13683.1 - 0.0026 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 OEU13683.1 - 0.0028 17.4 0.1 0.0072 16.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU13683.1 - 0.0039 17.1 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 OEU13683.1 - 0.0079 16.1 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OEU13683.1 - 0.012 15.4 1.3 0.026 14.2 0.7 1.9 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 OEU13683.1 - 0.012 15.4 0.6 0.031 14.0 0.5 1.9 2 1 0 2 2 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 OEU13683.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 OEU13683.1 - 0.077 13.2 0.0 0.34 11.2 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 OEU13683.1 - 0.081 12.5 1.2 0.81 9.2 1.2 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU13683.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OEU13683.1 - 0.13 11.9 0.1 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OEU13683.1 - 0.14 12.6 0.2 0.39 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OEU13683.1 - 0.17 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 OEU13684.1 - 5.5e-21 74.5 0.4 6.2e-21 74.4 0.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit zf_CCCH_4 PF18345.1 OEU13685.1 - 4e-11 42.6 25.8 2.7e-05 24.1 0.7 4.1 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 OEU13685.1 - 4.6e-08 32.8 19.0 0.00075 19.3 3.7 4.0 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OEU13685.1 - 1.7e-06 28.7 14.1 0.014 16.0 5.0 2.7 1 1 2 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 OEU13685.1 - 3e-05 24.3 20.5 0.0033 17.8 1.8 3.2 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 OEU13685.1 - 0.0021 17.8 20.3 0.0023 17.7 0.1 3.8 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OEU13685.1 - 0.015 15.5 13.1 0.047 13.9 3.7 2.2 1 1 1 2 2 2 0 Zinc-finger containing family Fasciclin PF02469.22 OEU13686.1 - 2.7e-22 79.4 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain LRR_4 PF12799.7 OEU13687.1 - 2.7e-07 30.8 0.7 0.0067 16.8 0.1 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13687.1 - 1e-05 25.2 0.6 0.00029 20.5 0.1 2.3 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 OEU13687.1 - 0.018 15.5 0.9 3.2 8.7 0.7 3.9 4 1 0 4 4 4 0 Leucine Rich Repeat Utp14 PF04615.13 OEU13688.1 - 0.0046 15.6 37.8 0.0057 15.3 37.8 1.1 1 0 0 1 1 1 1 Utp14 protein Spt5_N PF11942.8 OEU13690.1 - 0.027 15.4 7.6 0.027 15.4 7.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Utp14 PF04615.13 OEU13690.1 - 0.58 8.7 25.9 0.9 8.0 25.9 1.2 1 0 0 1 1 1 0 Utp14 protein SelK_SelG PF10961.8 OEU13690.1 - 1.2 9.8 0.0 1.2 9.8 0.0 3.1 3 1 0 3 3 3 0 Selenoprotein SelK_SelG Pkinase PF00069.25 OEU13691.1 - 9.3e-57 192.4 0.1 1.1e-56 192.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13691.1 - 7.8e-25 87.6 0.1 1e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU13691.1 - 0.00018 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OEU13691.1 - 0.0017 18.0 0.0 0.0069 16.0 0.0 1.8 1 1 0 2 2 2 1 Choline/ethanolamine kinase ABC1 PF03109.16 OEU13691.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC1 family DUF1904 PF08921.11 OEU13691.1 - 0.11 12.8 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) AhpC-TSA_2 PF13911.6 OEU13693.1 - 2.5e-14 53.3 0.0 8.7e-14 51.6 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Actin PF00022.19 OEU13695.1 - 5.4e-144 479.8 0.0 1.9e-143 478.0 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OEU13695.1 - 0.054 12.3 0.0 0.34 9.7 0.0 2.2 3 0 0 3 3 3 0 MreB/Mbl protein Methyltransf_21 PF05050.12 OEU13696.1 - 6.2e-05 23.1 0.0 0.00014 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase FkbM domain LRR_4 PF12799.7 OEU13697.1 - 5.8e-33 112.4 25.2 1.6e-08 34.7 2.3 6.8 4 3 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13697.1 - 6.1e-24 83.6 14.7 2.1e-10 40.2 3.1 7.5 3 3 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 OEU13697.1 - 1.4e-11 44.3 10.0 6.7e-06 25.7 0.9 3.7 2 2 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OEU13697.1 - 9.3e-11 40.9 25.1 0.023 14.7 0.4 8.8 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 OEU13697.1 - 4.1e-08 32.7 18.6 5.7 7.9 0.1 9.4 10 0 0 10 10 10 3 Leucine Rich Repeat AAA_33 PF13671.6 OEU13698.1 - 0.00081 19.6 0.0 0.0014 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU13698.1 - 0.00083 18.7 0.0 0.0029 16.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin IPT PF01745.16 OEU13698.1 - 0.033 13.6 0.5 0.86 8.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DUF2507 PF10702.9 OEU13700.1 - 0.0076 16.2 1.0 0.02 14.8 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2507) Actin PF00022.19 OEU13702.1 - 5.4e-144 479.8 0.0 1.9e-143 478.0 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OEU13702.1 - 0.054 12.3 0.0 0.34 9.7 0.0 2.2 3 0 0 3 3 3 0 MreB/Mbl protein Chloroa_b-bind PF00504.21 OEU13703.1 - 6.5e-38 130.8 0.2 8.4e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PDZ_6 PF17820.1 OEU13704.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Ras PF00071.22 OEU13705.1 - 2.4e-59 199.6 0.0 2.9e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU13705.1 - 2.5e-33 114.8 0.0 3.8e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU13705.1 - 8.2e-12 44.9 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU13705.1 - 6.1e-05 23.1 0.0 0.0001 22.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OEU13705.1 - 0.001 18.5 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OEU13705.1 - 0.0025 17.8 0.1 0.35 10.8 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OEU13705.1 - 0.011 15.3 0.0 0.065 12.8 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OEU13705.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 OEU13705.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 OEU13705.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Actin PF00022.19 OEU13706.1 - 5.4e-144 479.8 0.0 1.9e-143 478.0 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OEU13706.1 - 0.054 12.3 0.0 0.34 9.7 0.0 2.2 3 0 0 3 3 3 0 MreB/Mbl protein SCP2 PF02036.17 OEU13708.1 - 4.1e-07 30.4 2.9 4.8e-06 27.0 2.9 2.1 1 1 0 1 1 1 1 SCP-2 sterol transfer family Peptidase_M11 PF05548.11 OEU13709.1 - 1.1e-07 31.3 0.2 3.1e-07 29.9 0.2 1.7 1 1 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_4 PF13583.6 OEU13709.1 - 5.6e-05 22.9 1.2 0.001 18.8 0.0 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OEU13709.1 - 0.00082 19.9 0.1 0.0071 16.9 0.0 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU13709.1 - 0.0023 17.8 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 OEU13709.1 - 0.0042 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 OEU13709.1 - 0.012 14.6 0.1 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 WD40 PF00400.32 OEU13710.1 - 1e-17 64.1 1.7 0.0022 18.8 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 OEU13710.1 - 0.0001 21.1 0.1 0.0028 16.4 0.0 2.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Aa_trans PF01490.18 OEU13711.1 - 5.1e-37 127.6 20.3 4e-29 101.5 13.4 3.2 2 1 1 3 3 3 2 Transmembrane amino acid transporter protein 7tm_3 PF00003.22 OEU13712.1 - 1.5e-30 106.7 22.3 2.3e-30 106.1 22.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OEU13712.1 - 2.4e-23 82.8 0.0 6e-23 81.5 0.0 1.6 1 1 1 2 2 2 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OEU13712.1 - 7.8e-05 22.5 0.2 0.00043 20.0 0.2 2.1 2 1 0 2 2 2 1 Periplasmic binding protein Fmp27_WPPW PF10359.9 OEU13712.1 - 0.003 16.5 0.6 0.0044 15.9 0.6 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain FA_desaturase PF00487.24 OEU13713.1 - 5.3e-24 85.4 18.5 7.8e-24 84.9 18.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF4286 PF14114.6 OEU13713.1 - 0.8 10.2 6.2 1.3 9.6 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF393 PF04134.12 OEU13714.1 - 2.4e-19 70.7 0.0 2.8e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 PrsW-protease PF13367.6 OEU13715.1 - 2.2e-05 24.0 8.2 0.0017 17.8 1.0 2.5 2 0 0 2 2 2 2 PrsW family intramembrane metalloprotease Saf_2TM PF18303.1 OEU13715.1 - 4.2 6.9 6.3 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain DUF2157 PF09925.9 OEU13715.1 - 5.3 6.8 8.6 14 5.5 3.8 3.7 5 0 0 5 5 5 0 Predicted membrane protein (DUF2157) KH_1 PF00013.29 OEU13716.1 - 2.9e-29 100.7 0.5 1.3e-13 50.5 0.1 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 OEU13716.1 - 0.00091 19.0 0.2 0.34 10.8 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 OEU13716.1 - 0.053 13.4 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 KH domain DUF3835 PF12927.7 OEU13716.1 - 0.52 11.2 3.5 2.1 9.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) 7tm_3 PF00003.22 OEU13717.1 - 1.3e-31 110.2 21.3 1.6e-31 109.9 21.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR rhaM PF05336.13 OEU13718.1 - 4.5e-08 33.1 0.0 6.9e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 L-rhamnose mutarotase Chloroa_b-bind PF00504.21 OEU13720.1 - 1.3e-34 120.1 0.0 1.9e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATP-grasp_4 PF13535.6 OEU13721.1 - 3.3e-25 88.5 0.0 2.3e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 OEU13721.1 - 6.9e-22 78.2 0.0 2.1e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 OEU13721.1 - 1.3e-20 74.0 0.0 5.6e-09 36.0 0.0 3.3 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 OEU13721.1 - 1e-08 35.0 0.0 0.002 17.9 0.0 4.3 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 OEU13721.1 - 1e-07 31.6 0.0 0.015 14.8 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain LAL_C2 PF18603.1 OEU13721.1 - 4.1e-05 23.7 0.0 0.0052 16.9 0.0 2.8 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 RimK PF08443.11 OEU13721.1 - 0.00089 18.9 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DUF1336 PF07059.12 OEU13722.1 - 4e-47 161.2 0.0 5.4e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Methyltrans_RNA PF04452.14 OEU13723.1 - 2.5e-25 89.1 0.0 6.2e-25 87.9 0.0 1.6 2 0 0 2 2 2 1 RNA methyltransferase SMC_Nse1 PF07574.13 OEU13724.1 - 5.4e-05 23.2 0.9 0.0029 17.5 0.1 3.1 2 2 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex DUF4611 PF15387.6 OEU13724.1 - 0.045 14.0 0.6 0.082 13.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFIIA PF03153.13 OEU13725.1 - 0.00019 21.5 27.3 0.00034 20.8 27.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BORG_CEP PF14957.6 OEU13725.1 - 0.0065 17.6 3.7 0.0065 17.6 3.7 2.5 2 0 0 2 2 2 1 Cdc42 effector FAR1 PF03101.15 OEU13725.1 - 0.059 14.1 8.5 1.8 9.3 0.8 2.6 2 0 0 2 2 2 0 FAR1 DNA-binding domain Exonuc_VII_L PF02601.15 OEU13725.1 - 0.13 11.8 11.4 0.2 11.2 11.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RuvX PF03652.15 OEU13726.1 - 1.4e-25 90.2 0.0 1.7e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Holliday junction resolvase Nuc_sug_transp PF04142.15 OEU13727.1 - 3.5e-40 138.1 19.7 3.9e-40 138.0 19.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OEU13727.1 - 3.4e-09 36.3 20.6 1.9e-08 33.9 20.6 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU13727.1 - 0.00045 20.4 2.1 0.00045 20.4 2.1 2.5 3 0 0 3 3 3 2 EamA-like transporter family PTR2 PF00854.21 OEU13730.1 - 5e-43 147.4 17.7 2.4e-26 92.5 4.0 2.2 1 1 1 2 2 2 2 POT family DHHC PF01529.20 OEU13731.1 - 1.3e-22 80.4 10.5 1.3e-22 80.4 10.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase SYS1 PF09801.9 OEU13731.1 - 0.018 15.2 2.5 0.019 15.1 0.3 2.0 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network AAA_16 PF13191.6 OEU13732.1 - 0.00018 21.9 0.3 0.00061 20.2 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OEU13732.1 - 0.00093 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA12 PF10443.9 OEU13732.1 - 0.0018 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein AAA_22 PF13401.6 OEU13732.1 - 0.0062 16.8 0.1 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OEU13732.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 OEU13732.1 - 0.031 14.3 0.2 0.057 13.4 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE S_4TM PF18159.1 OEU13732.1 - 0.043 13.1 0.6 0.061 12.6 0.0 1.4 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain AAA_7 PF12775.7 OEU13732.1 - 0.043 13.3 0.1 0.092 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Kinesin PF00225.23 OEU13732.1 - 0.05 12.5 0.1 0.091 11.7 0.1 1.3 1 1 0 1 1 1 0 Kinesin motor domain AAA PF00004.29 OEU13732.1 - 0.061 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OEU13732.1 - 0.068 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 OEU13732.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 OEU13733.1 - 3.8e-40 138.0 0.2 3.5e-29 101.9 0.2 2.4 2 1 0 2 2 2 2 Cytochrome P450 Spore-coat_CotD PF11122.8 OEU13734.1 - 0.042 14.7 0.7 0.042 14.7 0.7 2.1 2 0 0 2 2 2 0 Inner spore coat protein D DUF2968 PF11180.8 OEU13734.1 - 0.46 10.1 11.9 4.6 6.8 8.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) adh_short PF00106.25 OEU13735.1 - 3.2e-16 59.4 0.3 0.00044 19.8 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OEU13735.1 - 6.6e-05 22.6 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Secretin_N_2 PF07655.13 OEU13735.1 - 0.08 13.5 14.1 2.1 9.0 7.1 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain GST_N_2 PF13409.6 OEU13739.1 - 1.3e-10 41.5 1.1 2.4e-09 37.4 0.4 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU13739.1 - 2.1e-05 24.8 0.0 0.0001 22.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU13739.1 - 0.00011 22.3 0.1 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU13739.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU13739.1 - 0.012 16.0 0.1 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OEU13739.1 - 0.04 14.1 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF726 PF05277.12 OEU13740.1 - 1e-71 241.7 0.3 1.1e-34 119.9 0.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF726) DUF1612 PF07756.12 OEU13740.1 - 0.052 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) DUF3040 PF11239.8 OEU13740.1 - 0.058 13.7 0.3 0.17 12.1 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) VirJ PF06057.11 OEU13740.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) WW PF00397.26 OEU13742.1 - 2.5e-19 69.0 15.4 3.7e-10 39.7 5.4 2.1 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OEU13742.1 - 0.037 14.3 2.5 1.1 9.6 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Mustang PF15682.5 OEU13742.1 - 0.11 12.6 0.8 8.5 6.5 0.0 2.3 1 1 1 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 peroxidase PF00141.23 OEU13743.1 - 6.7e-45 153.6 0.0 9.6e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Glutaredoxin2_C PF04399.13 OEU13744.1 - 1.5e-27 96.0 0.0 1.5e-25 89.6 0.0 2.1 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 OEU13744.1 - 1.7e-08 34.8 0.0 3.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU13744.1 - 0.00013 22.2 0.0 0.00043 20.5 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU13744.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Pkinase PF00069.25 OEU13745.1 - 3.2e-08 33.2 0.0 6.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OEU13745.1 - 1e-05 25.4 2.5 0.84 10.1 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 OEU13745.1 - 0.0033 17.5 0.2 0.11 12.6 0.4 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OEU13745.1 - 0.038 12.6 0.5 0.29 9.6 0.5 2.0 1 1 0 1 1 1 0 Adaptin N terminal region Sporozoite_P67 PF05642.11 OEU13745.1 - 0.63 8.0 7.3 1.1 7.3 7.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA-synt_2c PF01411.19 OEU13746.1 - 1.1e-200 667.9 0.0 1.5e-200 667.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OEU13746.1 - 1.7e-14 53.6 0.1 4.9e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OEU13746.1 - 1.6e-10 41.5 1.7 4.1e-10 40.2 1.7 1.8 1 0 0 1 1 1 1 DHHA1 domain Peptidase_M24 PF00557.24 OEU13747.1 - 4.6e-15 55.9 0.1 7e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 CHMI PF02962.15 OEU13747.1 - 0.098 13.0 0.1 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 5-carboxymethyl-2-hydroxymuconate isomerase RRP14 PF15459.6 OEU13747.1 - 0.33 11.6 6.7 0.63 10.7 6.7 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Chloroa_b-bind PF00504.21 OEU13748.1 - 2e-36 126.0 0.2 2.8e-36 125.5 0.2 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 OEU13749.1 - 1e-23 84.7 0.1 1.3e-23 84.3 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TPR_2 PF07719.17 OEU13750.1 - 6e-06 26.0 1.2 0.0018 18.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13750.1 - 9.6e-05 22.0 1.3 0.0012 18.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU13750.1 - 0.0024 17.8 0.2 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU13750.1 - 0.013 15.6 2.6 0.019 15.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU13750.1 - 0.021 15.5 0.1 8.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU13750.1 - 0.096 13.0 0.9 0.49 10.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 OEU13750.1 - 0.21 12.5 4.0 5.4 8.1 0.2 4.3 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_11 PF13414.6 OEU13750.1 - 1.4 8.6 3.2 38 4.1 0.0 2.8 3 0 0 3 3 3 0 TPR repeat Hid1 PF12722.7 OEU13750.1 - 4.5 5.3 14.9 8.3 4.4 14.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AA_permease_2 PF13520.6 OEU13752.1 - 3.9e-44 151.1 38.9 3.9e-44 151.1 38.9 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 OEU13752.1 - 1.5e-25 89.8 30.6 1.5e-25 89.8 30.6 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OEU13752.1 - 1.8e-16 59.9 5.2 1.8e-16 59.9 5.2 4.4 5 0 0 5 5 5 2 C-terminus of AA_permease Snf7 PF03357.21 OEU13753.1 - 1e-35 122.9 18.4 1.2e-35 122.6 18.4 1.0 1 0 0 1 1 1 1 Snf7 DivIC PF04977.15 OEU13753.1 - 0.81 9.5 6.5 1.6 8.6 0.2 2.9 2 1 1 3 3 3 0 Septum formation initiator Pkinase PF00069.25 OEU13754.1 - 7.9e-20 71.3 0.1 9.5e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13754.1 - 9.9e-13 48.0 0.0 1.2e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU13754.1 - 0.00041 20.3 0.0 0.00041 20.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU13754.1 - 0.00057 19.3 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OEU13754.1 - 0.0026 16.6 0.1 0.0029 16.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OEU13754.1 - 0.0031 17.2 0.1 0.0035 17.0 0.1 1.0 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OEU13754.1 - 0.0067 15.8 0.0 0.0067 15.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OEU13754.1 - 0.046 13.4 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1387 PF07139.11 OEU13756.1 - 1.2 8.8 13.9 3 7.5 13.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CDC45 PF02724.14 OEU13756.1 - 4.8 5.4 8.6 8 4.6 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.9 OEU13756.1 - 7.9 4.6 18.2 13 3.9 18.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HNH_5 PF14279.6 OEU13757.1 - 5.3e-16 58.2 0.8 8.6e-16 57.6 0.8 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 OEU13757.1 - 1.5e-11 44.3 1.6 2.2e-11 43.8 1.6 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 OEU13757.1 - 1.9e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease NodZ PF05830.11 OEU13759.1 - 0.022 13.6 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) MscL PF01741.18 OEU13759.1 - 0.11 12.7 0.5 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Chorion_3 PF05387.11 OEU13759.1 - 0.17 11.5 3.3 0.43 10.2 3.3 1.6 1 1 0 1 1 1 0 Chorion family 3 GT-D PF08759.11 OEU13760.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold PGK PF00162.19 OEU13762.1 - 1.2e-151 505.0 0.5 1.4e-151 504.8 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF4431 PF14485.6 OEU13762.1 - 0.13 12.1 0.0 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) adh_short PF00106.25 OEU13763.1 - 8.1e-17 61.3 0.1 1.9e-08 34.0 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU13763.1 - 6.9e-08 32.3 0.1 0.00012 21.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU13763.1 - 2.8e-05 24.1 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 KR domain UBA_4 PF14555.6 OEU13763.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain BAT PF15915.5 OEU13763.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Lipase_3 PF01764.25 OEU13764.1 - 9.3e-21 74.2 0.0 7.5e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) SPESP1 PF15754.5 OEU13764.1 - 0.00097 18.4 4.2 0.00097 18.4 4.2 1.7 2 0 0 2 2 2 1 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 OEU13764.1 - 0.0012 18.8 2.0 0.0012 18.8 2.0 2.4 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Abhydrolase_1 PF00561.20 OEU13764.1 - 0.0043 16.7 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 OEU13764.1 - 0.0058 16.2 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 OEU13764.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 OEU13764.1 - 0.031 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OEU13764.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 OEU13764.1 - 0.077 13.6 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU13764.1 - 0.2 10.9 0.0 0.6 9.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MMR_HSR1 PF01926.23 OEU13765.1 - 1.5e-20 73.4 0.0 2.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 OEU13765.1 - 1.4e-14 53.6 0.9 2.4e-14 52.9 0.9 1.4 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.23 OEU13765.1 - 5.5e-08 33.0 0.6 0.0018 18.3 0.0 2.7 1 1 2 3 3 3 2 Dynamin family FeoB_N PF02421.18 OEU13765.1 - 2.9e-07 30.1 0.0 5.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OEU13765.1 - 1.3e-05 24.8 0.2 0.015 14.9 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU13765.1 - 0.00013 21.9 0.9 0.014 15.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 OEU13765.1 - 0.0049 16.6 0.1 0.028 14.2 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 OEU13765.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Peptidase_C4 PF00863.19 OEU13765.1 - 0.021 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 NOG1 PF06858.14 OEU13765.1 - 0.075 12.8 0.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Roc PF08477.13 OEU13765.1 - 0.096 12.9 0.0 6.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 OEU13765.1 - 0.12 12.2 0.2 3.5 7.4 0.0 2.2 1 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop EIIA-man PF03610.16 OEU13765.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 PTS system fructose IIA component DUF3039 PF11238.8 OEU13766.1 - 0.0074 16.0 3.2 1.4 8.7 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3039) Coatomer_WDAD PF04053.14 OEU13767.1 - 2.9e-104 349.6 0.0 4.2e-104 349.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OEU13767.1 - 2.3e-72 244.0 0.9 2.2e-48 165.0 1.5 2.2 1 1 1 2 2 2 2 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OEU13767.1 - 9.7e-43 143.3 18.6 2.7e-08 34.3 0.1 8.7 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU13767.1 - 6.9e-11 42.3 0.2 0.00031 21.0 0.1 5.3 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OEU13767.1 - 0.064 11.9 3.2 1.3 7.6 0.0 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF1336 PF07059.12 OEU13768.1 - 1.5e-45 156.0 0.0 1.9e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Caa3_CtaG PF09678.10 OEU13769.1 - 0.028 13.9 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) VPS13_C PF16909.5 OEU13770.1 - 2.5e-38 131.6 0.2 4.6e-33 114.5 0.0 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 OEU13770.1 - 1.1e-20 74.5 14.0 1.2e-16 61.2 8.3 5.9 3 1 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OEU13770.1 - 2.4e-15 56.7 0.1 2.4e-15 56.7 0.1 3.0 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 OEU13770.1 - 1.7e-13 50.5 9.2 2.9e-11 43.3 0.4 5.5 5 0 0 5 5 5 1 Repeating coiled region of VPS13 ATG_C PF09333.11 OEU13770.1 - 1.1e-08 35.3 0.0 4.6e-08 33.3 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PDZ PF00595.24 OEU13770.1 - 0.024 15.0 1.1 0.23 11.8 0.1 2.9 2 0 0 2 2 2 0 PDZ domain PDZ_6 PF17820.1 OEU13770.1 - 0.029 14.2 0.3 0.34 10.8 0.0 2.8 2 0 0 2 2 2 0 PDZ domain LSM PF01423.22 OEU13771.1 - 3.3e-14 52.3 0.0 7.1e-14 51.3 0.0 1.5 2 0 0 2 2 2 1 LSM domain Ndc1_Nup PF09531.10 OEU13772.1 - 1.5 7.4 9.1 1.7 7.3 9.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 OEU13772.1 - 2.7 6.7 10.1 3.1 6.5 10.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OEU13772.1 - 6.5 4.8 14.0 7.7 4.5 14.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FA_desaturase PF00487.24 OEU13774.1 - 7.5e-30 104.6 23.4 1e-29 104.1 23.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OEU13774.1 - 1.2e-08 34.9 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pex24p PF06398.11 OEU13774.1 - 0.47 9.4 4.6 0.99 8.3 0.8 2.4 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin VASt PF16016.5 OEU13775.1 - 4.6e-12 46.6 0.3 4.6e-12 46.6 0.3 2.5 2 1 1 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain E1-E2_ATPase PF00122.20 OEU13777.1 - 4.2e-18 65.5 0.1 6.3e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase EamA PF00892.20 OEU13778.1 - 6.2e-30 104.2 23.4 9.6e-15 55.0 7.0 2.6 2 1 0 2 2 2 2 EamA-like transporter family PAP_fibrillin PF04755.12 OEU13780.1 - 0.00085 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin DUF489 PF04356.12 OEU13782.1 - 0.0012 18.9 45.8 0.014 15.4 2.0 6.4 2 1 3 6 6 6 4 Protein of unknown function (DUF489) DUF1664 PF07889.12 OEU13782.1 - 0.0085 16.1 66.3 0.012 15.6 8.2 7.2 1 1 5 7 7 7 5 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 OEU13782.1 - 0.07 13.2 0.2 0.07 13.2 0.2 9.7 10 1 3 13 13 13 0 Basic region leucine zipper Ank_3 PF13606.6 OEU13783.1 - 1.5e-14 52.7 3.2 0.0014 19.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OEU13783.1 - 1.2e-13 51.4 0.0 1.8e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU13783.1 - 8.2e-10 38.7 3.2 0.047 14.2 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OEU13783.1 - 9.5e-10 38.6 0.3 0.00062 20.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU13783.1 - 8.1e-08 32.7 0.5 0.0039 17.7 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF5492 PF17596.2 OEU13783.1 - 0.031 14.6 0.3 31 5.0 0.0 3.2 2 1 0 3 3 3 0 Family of unknown function (DUF5492) DUF5593 PF18007.1 OEU13783.1 - 0.093 13.4 0.0 10 6.9 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5593) HECT PF00632.25 OEU13784.1 - 1.8e-80 270.7 0.1 2.2e-80 270.4 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Metallophos PF00149.28 OEU13785.1 - 3.4e-33 115.9 0.3 5.2e-33 115.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OEU13785.1 - 0.0027 18.1 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain MFS_5 PF05631.14 OEU13786.1 - 2.8e-79 266.6 6.8 4.4e-79 265.9 6.8 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM IMPDH PF00478.25 OEU13787.1 - 5.5e-127 423.5 6.0 6.3e-127 423.3 6.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OEU13787.1 - 3.6e-13 49.8 0.0 6.7e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 OEU13787.1 - 3.2e-09 36.6 3.6 6.5e-06 25.8 1.2 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OEU13787.1 - 9.5e-07 28.2 2.1 1.7e-06 27.3 2.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OEU13787.1 - 0.00052 19.5 0.4 0.0051 16.3 0.1 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 OEU13787.1 - 0.002 17.3 1.3 0.099 11.8 1.3 2.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 OEU13787.1 - 0.0036 16.6 4.2 0.0076 15.6 0.5 2.2 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 OEU13787.1 - 0.023 14.1 0.3 0.67 9.3 0.1 2.4 2 0 0 2 2 2 0 KDPG and KHG aldolase Dus PF01207.17 OEU13787.1 - 0.03 13.4 0.3 1.8 7.6 0.0 2.3 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) SapB_2 PF03489.17 OEU13788.1 - 0.18 11.9 0.5 6.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 EMP70 PF02990.16 OEU13790.1 - 1.5e-155 518.8 11.1 2.3e-155 518.2 11.1 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Chloroa_b-bind PF00504.21 OEU13791.1 - 2.4e-36 125.7 0.0 3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TPT PF03151.16 OEU13792.1 - 8.6e-67 225.5 14.0 9.8e-67 225.3 14.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU13792.1 - 3e-07 30.7 18.6 1.2e-05 25.5 2.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OEU13792.1 - 2.2e-05 23.8 1.4 2.2e-05 23.8 1.4 2.1 2 0 0 2 2 2 1 UAA transporter family Adeno_E3_14_5 PF04834.12 OEU13792.1 - 0.028 14.9 0.0 0.075 13.6 0.0 1.7 1 0 0 1 1 1 0 Early E3 14.5 kDa protein MccV PF17508.2 OEU13792.1 - 0.66 10.6 0.1 0.66 10.6 0.1 2.7 3 0 0 3 3 3 0 Microcin V bacteriocin DUF4231 PF14015.6 OEU13792.1 - 7.5 7.1 12.7 0.15 12.5 0.6 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF4231) S4_2 PF13275.6 OEU13793.1 - 1.6e-21 75.8 0.3 1.7e-21 75.8 0.3 1.0 1 0 0 1 1 1 1 S4 domain PTPS PF01242.19 OEU13794.1 - 8.6e-19 67.7 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Methyltransf_16 PF10294.9 OEU13795.1 - 1.4e-12 47.7 1.0 1.5e-10 41.1 1.0 2.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 OEU13795.1 - 0.027 15.2 0.2 0.065 14.0 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.17 OEU13796.1 - 1.7e-46 159.1 0.0 1.7e-46 159.1 0.0 5.0 3 1 1 4 4 4 1 C-5 cytosine-specific DNA methylase Ribonuclease_3 PF00636.26 OEU13796.1 - 6.3e-26 91.1 0.2 1.4e-15 57.8 0.0 4.1 3 1 0 3 3 3 2 Ribonuclease III domain DEAD PF00270.29 OEU13796.1 - 1.5e-17 63.9 0.1 1.3e-16 60.9 0.1 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Ribonucleas_3_3 PF14622.6 OEU13796.1 - 4.5e-16 59.2 0.0 4.1e-08 33.4 0.0 3.3 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 OEU13796.1 - 8.1e-10 39.0 4.5 1.3e-09 38.4 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU13796.1 - 6.5e-07 29.5 0.0 6.5e-07 29.5 0.0 5.9 3 2 3 6 6 6 2 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 OEU13796.1 - 8.2e-05 22.7 0.1 0.00023 21.3 0.1 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain ATP-grasp PF02222.22 OEU13797.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain CytB6-F_Fe-S PF08802.10 OEU13797.1 - 0.76 9.9 4.3 4.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit TLC PF03219.14 OEU13798.1 - 1.4e-07 30.6 4.3 3.3e-05 22.8 0.1 2.5 2 1 0 3 3 3 2 TLC ATP/ADP transporter DUF1541 PF07563.11 OEU13799.1 - 0.0072 16.2 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1541) HLH PF00010.26 OEU13799.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain MPC PF03650.13 OEU13800.1 - 1.2e-18 67.3 0.2 1.2e-18 67.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Popeye PF04831.13 OEU13800.1 - 0.022 14.9 0.2 0.024 14.8 0.2 1.2 1 0 0 1 1 1 0 Popeye protein conserved region DUF5562 PF17717.1 OEU13800.1 - 0.065 13.2 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5562) MPC PF03650.13 OEU13801.1 - 2.1e-24 85.8 0.1 2.2e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers BcsB PF03170.13 OEU13801.1 - 0.2 10.0 0.1 0.19 10.0 0.1 1.0 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit zf-LSD1 PF06943.12 OEU13802.1 - 0.0044 16.8 1.8 0.0044 16.8 1.8 2.2 2 0 0 2 2 2 1 LSD1 zinc finger DZR PF12773.7 OEU13802.1 - 0.024 14.7 7.8 0.035 14.1 7.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.13 OEU13802.1 - 0.032 14.0 0.5 0.032 14.0 0.5 2.7 3 0 0 3 3 3 0 InsA N-terminal domain PRANC PF09372.10 OEU13803.1 - 0.0097 16.2 3.9 4.7 7.6 0.8 3.2 3 1 1 4 4 4 2 PRANC domain F-box PF00646.33 OEU13803.1 - 0.058 13.3 0.1 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 OEU13803.1 - 0.066 13.1 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 F-box-like DUF3475 PF11961.8 OEU13803.1 - 0.088 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) zf-RING_2 PF13639.6 OEU13804.1 - 6.8e-09 35.9 15.8 2.4e-07 31.0 11.1 2.4 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU13804.1 - 9e-06 25.4 4.5 9e-06 25.4 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU13804.1 - 2.8e-05 23.9 2.0 2.8e-05 23.9 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU13804.1 - 6.9e-05 23.1 12.7 0.00022 21.5 12.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU13804.1 - 0.00015 21.6 8.0 0.00036 20.3 8.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU13804.1 - 0.0016 18.3 12.9 0.0073 16.2 12.9 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU13804.1 - 0.016 15.2 6.6 0.016 15.2 6.6 2.7 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.7 OEU13804.1 - 0.035 14.2 4.2 0.035 14.2 4.2 2.4 2 1 0 2 2 2 0 RING-variant domain YqzE PF14038.6 OEU13804.1 - 0.04 13.9 0.6 0.082 12.9 0.6 1.4 1 0 0 1 1 1 0 YqzE-like protein zf-ANAPC11 PF12861.7 OEU13804.1 - 0.043 13.9 6.6 0.15 12.1 6.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 OEU13804.1 - 0.057 13.1 6.0 0.044 13.5 2.8 2.3 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_4 PF14447.6 OEU13804.1 - 0.25 11.2 8.8 0.91 9.4 8.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OEU13804.1 - 2.2 8.1 18.5 2.6 7.9 7.3 3.1 2 1 1 3 3 3 0 RING-like zinc finger CitMHS PF03600.16 OEU13805.1 - 0.02 14.1 0.2 0.025 13.8 0.2 1.1 1 0 0 1 1 1 0 Citrate transporter DUF5058 PF16481.5 OEU13805.1 - 0.023 14.4 1.4 0.79 9.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5058) Pilin_N PF07790.11 OEU13805.1 - 0.071 14.0 0.0 0.19 12.7 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal CRA PF06589.11 OEU13805.1 - 0.085 13.0 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF2207 PF09972.9 OEU13805.1 - 0.11 11.3 4.2 0.31 9.8 0.8 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4939 PF16297.5 OEU13806.1 - 0.085 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) MFS_1 PF07690.16 OEU13807.1 - 9.5e-12 44.5 31.6 4.7e-11 42.2 31.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TAF PF02969.17 OEU13807.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3087 PF11286.8 OEU13807.1 - 4.1 6.8 5.2 12 5.3 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Connexin PF00029.19 OEU13808.1 - 0.012 15.4 0.2 0.012 15.4 0.2 3.8 4 0 0 4 4 4 0 Connexin Sas10_Utp3 PF04000.15 OEU13808.1 - 0.033 14.8 2.0 0.033 14.8 2.0 3.3 1 1 1 2 2 2 0 Sas10/Utp3/C1D family Goodbye PF17109.5 OEU13808.1 - 1.2 9.6 11.7 0.66 10.4 1.4 3.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain MSV199 PF10553.9 OEU13808.1 - 1.8 8.8 8.2 0.3 11.4 0.2 3.1 1 1 1 2 2 2 0 MSV199 domain Iron_permease PF04120.12 OEU13808.1 - 2.1 8.1 10.0 0.63 9.8 1.7 3.0 2 0 0 2 2 2 0 Low affinity iron permease CaMKII_AD PF08332.10 OEU13809.1 - 8.6e-19 67.9 0.0 5.6e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 OEU13809.1 - 1.2e-14 54.6 0.6 2.3e-06 27.9 0.1 2.7 2 1 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 OEU13809.1 - 5.2e-08 33.3 0.1 0.00077 19.8 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 OEU13809.1 - 3.7e-06 27.1 1.8 0.076 13.1 0.1 2.5 3 0 0 3 3 3 2 SnoaL-like domain SnoaL_2 PF12680.7 OEU13809.1 - 0.0099 16.5 0.0 0.3 11.7 0.0 2.3 2 1 0 2 2 2 1 SnoaL-like domain Alfin PF12165.8 OEU13809.1 - 0.016 14.9 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Alfin Y_Y_Y PF07495.13 OEU13809.1 - 0.028 14.4 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Y_Y_Y domain TPP1 PF10341.9 OEU13810.1 - 4.4e-05 23.4 0.2 0.00022 21.2 0.2 2.2 1 1 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD FGGY_C PF02782.16 OEU13811.1 - 1e-07 31.9 0.0 2.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OEU13811.1 - 2e-05 24.3 0.4 0.036 13.6 0.0 2.8 4 0 0 4 4 4 2 FGGY family of carbohydrate kinases, N-terminal domain Apis_Csd PF11671.8 OEU13811.1 - 3 7.9 8.6 6.7 6.7 4.5 3.1 3 0 0 3 3 3 0 Complementary sex determiner protein ELFV_dehydrog PF00208.21 OEU13812.1 - 7.7e-39 133.9 0.0 1.1e-38 133.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OEU13812.1 - 1.6e-08 32.7 0.1 0.0033 15.0 0.0 3.3 3 0 0 3 3 3 3 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 OEU13812.1 - 0.00095 19.1 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ins_allergen_rp PF06757.13 OEU13812.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification EcoR124_C PF12008.8 OEU13812.1 - 0.17 11.5 0.9 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Sulfotransfer_3 PF13469.6 OEU13813.1 - 0.00064 20.2 0.1 0.028 14.8 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family Mito_carr PF00153.27 OEU13814.1 - 1e-49 166.4 2.9 8.4e-17 60.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MRP-S31 PF15433.6 OEU13815.1 - 1.8 8.2 8.1 2 8.0 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SQHop_cyclase_C PF13243.6 OEU13816.1 - 4.1e-48 164.1 3.0 3.7e-45 154.4 0.8 2.7 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OEU13816.1 - 6.1e-48 163.4 0.5 4e-39 134.4 0.0 4.7 4 1 1 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OEU13816.1 - 3.2e-26 90.8 22.1 8.8e-07 28.6 2.6 7.1 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 OEU13816.1 - 5.5e-05 22.6 0.1 0.23 10.8 0.0 3.9 2 2 0 3 3 3 1 Pectic acid lyase Mito_carr PF00153.27 OEU13817.1 - 3e-67 222.6 1.5 4.7e-22 77.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TMEM187 PF15100.6 OEU13817.1 - 0.007 16.0 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 TMEM187 protein family TraB PF01963.17 OEU13818.1 - 0.00063 19.7 0.0 0.013 15.4 0.0 2.5 3 0 0 3 3 3 1 TraB family ArsR PF09824.9 OEU13818.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator Pkinase PF00069.25 OEU13819.1 - 6e-20 71.7 0.6 5.6e-16 58.7 0.1 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13819.1 - 1.1e-18 67.5 13.9 2.2e-08 33.7 11.6 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OEU13819.1 - 0.00055 19.4 0.0 0.0018 17.7 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU13819.1 - 0.052 12.9 0.0 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like EBP PF05241.12 OEU13820.1 - 8.3e-06 25.4 2.8 1.6e-05 24.5 2.8 1.6 1 1 0 1 1 1 1 Emopamil binding protein DUF1910 PF08928.10 OEU13820.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PqiA PF04403.13 OEU13821.1 - 7.2e-11 42.2 33.0 8.8e-08 32.1 3.4 3.6 3 1 0 4 4 4 2 Paraquat-inducible protein A AHH PF14412.6 OEU13821.1 - 0.19 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Chordopox_A33R PF05966.12 OEU13822.1 - 0.035 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A33R protein WD40 PF00400.32 OEU13823.1 - 7.1e-48 159.6 22.5 4.1e-09 36.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU13823.1 - 2.6e-12 46.8 0.4 0.051 13.9 0.0 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU13823.1 - 0.00076 18.5 0.1 0.86 8.5 0.0 3.7 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OEU13823.1 - 0.0018 17.0 7.4 0.11 11.2 0.1 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OEU13823.1 - 0.0042 15.7 0.0 0.025 13.1 0.0 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 OEU13823.1 - 0.074 12.4 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Asp-B-Hydro_N PF05279.11 OEU13825.1 - 4.5 7.3 14.3 5.5 7.0 14.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RRM_1 PF00076.22 OEU13826.1 - 7.4e-77 253.2 0.0 1.4e-20 72.9 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OEU13826.1 - 1.1e-08 34.8 0.0 0.033 14.0 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 OEU13826.1 - 6.6e-08 32.5 0.7 0.22 11.6 0.0 4.8 5 0 0 5 5 5 3 RNA binding motif DUF3343 PF11823.8 OEU13826.1 - 0.0001 21.7 0.0 3.9 7.0 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3343) Nup35_RRM_2 PF14605.6 OEU13826.1 - 0.00015 21.7 0.0 0.27 11.2 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 OEU13826.1 - 0.0016 18.4 0.4 7 6.8 0.0 4.0 4 0 0 4 4 4 1 Limkain b1 DbpA PF03880.15 OEU13826.1 - 0.038 14.0 0.0 45 4.1 0.0 4.0 4 0 0 4 4 4 0 DbpA RNA binding domain RRM_7 PF16367.5 OEU13826.1 - 0.058 13.5 0.0 2.4 8.3 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif DUF4926 PF16277.5 OEU13826.1 - 0.15 11.5 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) YflT PF11181.8 OEU13826.1 - 0.45 11.1 3.0 31 5.1 0.1 4.4 5 0 0 5 5 5 0 Heat induced stress protein YflT GRP PF07172.11 OEU13826.1 - 2.4 8.9 48.3 4.3 8.1 16.4 3.8 3 0 0 3 3 3 0 Glycine rich protein family NadA PF02445.16 OEU13827.1 - 3.7e-33 115.0 0.7 4.6e-32 111.4 0.1 2.2 1 1 0 2 2 2 2 Quinolinate synthetase A protein Methyltransf_21 PF05050.12 OEU13828.1 - 7.1e-11 42.4 0.0 9.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain GlutR_N PF05201.15 OEU13829.1 - 0.31 10.8 2.8 0.58 9.9 2.3 1.6 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Semialdhyde_dhC PF02774.18 OEU13830.1 - 1.8e-42 145.5 0.0 2.4e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OEU13830.1 - 4.8e-25 88.3 0.1 1.4e-24 86.8 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OEU13830.1 - 8.1e-06 26.3 0.8 1.4e-05 25.6 0.3 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent WD40 PF00400.32 OEU13832.1 - 4.5e-07 30.5 9.9 1.3 10.0 0.0 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU13832.1 - 0.00087 19.5 0.0 6.3 7.2 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OEU13832.1 - 0.0089 15.4 0.0 0.023 14.1 0.0 1.5 1 1 1 2 2 2 1 WD40-like domain Antimicrobial22 PF16047.5 OEU13832.1 - 0.034 14.0 1.5 0.067 13.1 1.5 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF2138 PF09909.9 OEU13832.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) EpuA PF11772.8 OEU13832.1 - 0.17 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Fumerase_C PF05683.12 OEU13833.1 - 3.5e-84 281.2 0.0 6.1e-84 280.4 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 OEU13833.1 - 1.4e-82 277.1 0.0 2e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Galactosyl_T PF01762.21 OEU13834.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase TRAM_LAG1_CLN8 PF03798.16 OEU13836.1 - 0.00051 19.8 27.1 0.0017 18.1 16.4 2.9 1 1 1 2 2 2 2 TLC domain Phage_Gp23 PF10669.9 OEU13836.1 - 0.064 13.6 0.5 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF443 PF04276.12 OEU13836.1 - 4.3 7.1 9.9 23 4.7 9.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF443) GDI PF00996.18 OEU13837.1 - 3.4e-183 609.1 0.0 4e-183 608.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor ZZ PF00569.17 OEU13840.1 - 0.02 14.7 2.2 75 3.2 0.0 4.1 4 0 0 4 4 4 0 Zinc finger, ZZ type Tudor_3 PF18115.1 OEU13841.1 - 0.33 10.8 1.1 0.48 10.3 0.2 1.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain GTP_EFTU PF00009.27 OEU13842.1 - 9.3e-45 152.5 0.0 1.3e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OEU13842.1 - 1.2e-17 64.3 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OEU13842.1 - 9.2e-09 35.6 0.3 3.5e-08 33.7 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OEU13842.1 - 1e-05 25.3 1.6 4.1e-05 23.4 0.9 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OEU13842.1 - 0.00012 22.1 0.0 0.0032 17.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Na_H_Exchanger PF00999.21 OEU13844.1 - 5.4e-53 180.1 13.2 6.9e-53 179.8 13.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PHO4 PF01384.20 OEU13844.1 - 0.0096 15.0 1.1 0.017 14.1 1.1 1.8 1 1 0 1 1 1 1 Phosphate transporter family DnaJ PF00226.31 OEU13847.1 - 1e-15 57.6 1.4 2.1e-15 56.6 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain TFIIF_alpha PF05793.12 OEU13848.1 - 3.7 6.0 7.8 4.3 5.8 7.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) adh_short PF00106.25 OEU13850.1 - 3.7e-26 91.8 0.0 8.1e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU13850.1 - 6.8e-15 55.3 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU13850.1 - 1.8e-09 37.7 0.2 5.8e-09 36.1 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OEU13850.1 - 0.037 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family potato_inhibit PF00280.18 OEU13851.1 - 0.041 14.5 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Potato inhibitor I family Tetraspanin PF00335.20 OEU13851.1 - 1.5 8.5 6.3 1.7 8.3 3.0 2.5 3 1 0 3 3 3 0 Tetraspanin family TPR_7 PF13176.6 OEU13853.1 - 0.0017 18.2 0.6 0.68 10.1 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU13853.1 - 0.0054 16.6 0.5 1.6 8.7 0.5 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU13853.1 - 0.015 15.6 0.0 5 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat K_channel_TID PF07941.11 OEU13853.1 - 2.9 8.4 7.3 0.87 10.1 2.8 2.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain LMBR1 PF04791.16 OEU13853.1 - 6.9 5.5 6.5 9.9 4.9 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein BUD22 PF09073.10 OEU13854.1 - 0.00091 18.7 5.9 3.4 6.9 0.0 2.1 1 1 1 2 2 2 1 BUD22 TPR_10 PF13374.6 OEU13854.1 - 0.0025 17.6 0.4 0.01 15.6 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Porph_ging PF09697.10 OEU13854.1 - 0.017 15.7 8.2 0.15 12.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (Porph_ging) TPR_2 PF07719.17 OEU13854.1 - 0.061 13.5 0.0 2.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU13854.1 - 0.31 11.2 3.7 1.2 9.3 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Coat_F PF07875.12 OEU13854.1 - 1.4 9.2 12.0 0.054 13.7 1.8 3.3 3 0 0 3 3 3 0 Coat F domain Hydin_ADK PF17213.3 OEU13854.1 - 4.8 7.4 14.9 2.1 8.6 6.9 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Myb_DNA-bind_5 PF13873.6 OEU13856.1 - 0.059 13.5 0.4 0.059 13.5 0.4 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3439 PF11921.8 OEU13857.1 - 8.6 6.3 11.8 0.73 9.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TRAM_LAG1_CLN8 PF03798.16 OEU13858.1 - 0.0025 17.6 16.9 0.03 14.1 15.0 2.6 1 1 1 2 2 2 1 TLC domain DUF5086 PF16985.5 OEU13859.1 - 0.036 14.0 1.9 0.085 12.8 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5086) Glyco_tranf_2_4 PF13704.6 OEU13863.1 - 2.2e-06 28.1 5.4 2.2e-06 28.1 5.4 3.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 LIDHydrolase PF10230.9 OEU13864.1 - 5.7e-26 91.7 0.0 7.2e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ependymin PF00811.18 OEU13865.1 - 0.086 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Ependymin Nup54 PF13874.6 OEU13866.1 - 2.4 8.3 12.4 0.15 12.2 3.8 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 eIF-4B PF06273.11 OEU13867.1 - 0.022 13.9 0.5 0.022 13.9 0.5 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B APG6_N PF17675.1 OEU13868.1 - 0.0032 18.0 4.6 0.0032 18.0 4.6 4.7 4 1 1 5 5 5 1 Apg6 coiled-coil region Dynein_AAA_lid PF17852.1 OEU13869.1 - 0.084 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain MerR-DNA-bind PF09278.11 OEU13870.1 - 0.074 13.6 0.3 0.13 12.8 0.3 1.3 1 0 0 1 1 1 0 MerR, DNA binding TPR_12 PF13424.6 OEU13873.1 - 2.1e-30 104.8 0.0 7.8e-18 64.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU13873.1 - 9.7e-24 82.5 0.1 9.6e-11 41.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU13873.1 - 1.9e-07 30.6 0.0 3.4e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13873.1 - 4.2e-06 26.3 0.0 3.1e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU13873.1 - 1.8e-05 24.5 0.0 0.0031 17.5 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU13873.1 - 3.8e-05 23.6 0.0 0.0015 18.6 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU13873.1 - 0.013 16.1 0.0 0.12 13.1 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU13873.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 MalT-like TPR region TPR_14 PF13428.6 OEU13873.1 - 0.021 15.6 0.1 1.1 10.3 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OEU13873.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DUF1681 PF07933.14 OEU13875.1 - 1.9e-27 95.8 0.0 2.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SET PF00856.28 OEU13876.1 - 6.2e-07 30.0 0.0 0.0032 17.9 0.0 2.8 2 2 0 2 2 2 2 SET domain F-box-like PF12937.7 OEU13877.1 - 0.00053 19.8 0.2 0.0013 18.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU13877.1 - 0.061 13.2 0.6 0.29 11.1 0.1 2.5 2 0 0 2 2 2 0 F-box domain PrpF PF04303.13 OEU13879.1 - 1.5e-52 178.8 17.2 1.8e-36 125.9 6.4 6.5 2 2 3 5 5 5 5 PrpF protein Trypsin_2 PF13365.6 OEU13880.1 - 1.5e-15 58.4 0.6 3.8e-14 53.8 0.0 3.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain Roc PF08477.13 OEU13880.1 - 3.2e-15 56.4 0.0 5.4e-14 52.4 0.0 2.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 OEU13880.1 - 4.6e-14 52.3 7.1 1.1e-05 25.6 0.4 4.1 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13880.1 - 2.2e-12 46.6 10.9 1.7e-08 34.1 1.2 3.7 1 1 2 3 3 3 3 Leucine rich repeat Ras PF00071.22 OEU13880.1 - 1.4e-06 28.0 0.0 4.7e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Ras family COR PF16095.5 OEU13880.1 - 0.00021 21.1 0.0 0.76 9.6 0.0 3.0 3 0 0 3 3 3 2 C-terminal of Roc, COR, domain LRR_1 PF00560.33 OEU13880.1 - 0.00053 20.2 7.4 4.7 8.2 0.1 6.9 6 1 0 6 6 5 1 Leucine Rich Repeat Gtr1_RagA PF04670.12 OEU13880.1 - 0.0012 18.3 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU13880.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 OEU13880.1 - 0.062 12.7 0.1 2 7.8 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family LRR_9 PF14580.6 OEU13880.1 - 0.097 12.2 2.4 1.6 8.2 0.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 OEU13880.1 - 0.21 11.7 11.9 3.3 8.0 0.4 6.0 6 0 0 6 6 6 0 Leucine Rich repeat ThiD2 PF17792.1 OEU13881.1 - 0.081 13.4 0.2 0.42 11.1 0.2 2.2 1 0 0 1 1 1 0 ThiD2 family ABC2_membrane PF01061.24 OEU13882.1 - 1.3e-31 109.7 9.4 1.3e-31 109.7 9.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OEU13882.1 - 8.3e-11 41.6 3.0 1e-10 41.3 3.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OEU13882.1 - 1.9e-07 31.7 0.1 3.2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU13882.1 - 0.0024 17.8 0.1 0.0038 17.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OEU13882.1 - 0.0058 17.2 0.2 0.011 16.2 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU13882.1 - 0.0067 16.8 0.4 0.025 15.0 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OEU13882.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OEU13882.1 - 0.018 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OEU13882.1 - 0.037 14.3 0.2 0.14 12.5 0.4 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OEU13882.1 - 0.074 12.8 0.5 0.16 11.7 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 OEU13882.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OEU13882.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_S30 PF04758.14 OEU13883.1 - 2.6e-29 101.2 8.5 3e-29 101.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 PseudoU_synth_1 PF01416.20 OEU13885.1 - 5.2e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridine synthase Methyltransf_21 PF05050.12 OEU13885.1 - 1.4e-05 25.2 0.0 4.2e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-C2H2_4 PF13894.6 OEU13885.1 - 0.0089 16.8 0.4 0.048 14.5 0.4 2.3 1 0 0 1 1 1 1 C2H2-type zinc finger V_cholerae_RfbT PF05575.11 OEU13885.1 - 0.024 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Methyltransf_23 PF13489.6 OEU13885.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2 PF00096.26 OEU13885.1 - 0.077 13.5 0.3 0.3 11.6 0.3 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type PseudoU_synth_1 PF01416.20 OEU13886.1 - 0.0011 19.4 0.0 0.0028 18.1 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridine synthase zf-C2H2_4 PF13894.6 OEU13886.1 - 0.0028 18.3 0.5 0.0082 16.9 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OEU13886.1 - 0.0055 17.1 1.2 0.015 15.7 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OEU13886.1 - 0.06 13.1 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OEU13886.1 - 0.37 11.1 2.6 0.44 10.9 1.2 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MBOAT_2 PF13813.6 OEU13888.1 - 7.9e-10 38.9 0.1 3.9e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.19 OEU13888.1 - 9.9e-09 35.0 3.1 2e-08 34.0 3.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Zip PF02535.22 OEU13888.1 - 0.059 12.6 3.4 0.076 12.2 1.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3943 PF13084.6 OEU13888.1 - 0.079 12.8 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) HhH-GPD PF00730.25 OEU13889.1 - 1.9e-15 57.2 0.0 2.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OEU13889.1 - 0.00047 19.9 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.6 OEU13889.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 1 1 2 2 2 0 Helix-hairpin-helix domain DUF5623 PF18536.1 OEU13889.1 - 0.16 12.3 0.0 18 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Rhodanese PF00581.20 OEU13890.1 - 1.2e-07 32.3 0.0 2.1e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain TraB PF01963.17 OEU13891.1 - 1.5e-10 41.4 2.6 8.7e-10 38.9 2.6 2.0 1 1 0 1 1 1 1 TraB family VPS28 PF03997.12 OEU13891.1 - 0.012 15.3 0.3 0.029 14.1 0.3 1.6 1 0 0 1 1 1 0 VPS28 protein DUF1298 PF06974.13 OEU13892.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) FA_desaturase PF00487.24 OEU13894.1 - 1.2e-19 71.2 3.4 1e-11 45.2 2.6 2.2 1 1 1 2 2 2 2 Fatty acid desaturase FUN14 PF04930.15 OEU13895.1 - 1.1e-18 67.4 0.9 1.2e-18 67.3 0.9 1.1 1 0 0 1 1 1 1 FUN14 family DUF3947 PF13135.6 OEU13896.1 - 0.035 14.3 1.7 0.035 14.3 1.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) Gln-synt_N PF03951.19 OEU13896.1 - 0.039 13.7 0.5 0.13 12.0 0.4 1.9 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain RNA_pol_Rpb1_7 PF04990.12 OEU13896.1 - 0.11 12.4 3.1 1.6 8.7 1.8 2.4 1 1 0 2 2 2 0 RNA polymerase Rpb1, domain 7 AIM3 PF17096.5 OEU13896.1 - 2.4 9.2 6.8 1.6 9.7 0.2 2.8 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 SR-25 PF10500.9 OEU13896.1 - 9.8 5.7 27.7 0.19 11.3 8.5 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Img2 PF05046.14 OEU13899.1 - 5.3e-09 36.3 0.9 1.1e-08 35.3 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) SAP PF02037.27 OEU13899.1 - 1.1e-07 31.4 0.6 2.6e-07 30.2 0.6 1.7 1 0 0 1 1 1 1 SAP domain SUI1 PF01253.22 OEU13899.1 - 4.3e-06 27.2 1.9 3.2e-05 24.4 1.4 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 SMN PF06003.12 OEU13899.1 - 0.68 9.1 5.3 0.22 10.8 0.2 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Allantoicase PF03561.15 OEU13901.1 - 1.7e-84 281.0 0.0 6.9e-45 152.6 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Fungus-induced PF10917.8 OEU13902.1 - 0.11 12.8 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein Methyltransf_24 PF13578.6 OEU13903.1 - 8.2e-05 23.6 0.0 0.00031 21.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF4834 PF16118.5 OEU13903.1 - 0.0053 17.7 2.9 0.013 16.5 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Protocadherin PF08374.11 OEU13903.1 - 0.011 15.7 2.6 0.02 14.9 2.6 1.3 1 0 0 1 1 1 0 Protocadherin COX14 PF14880.6 OEU13903.1 - 0.014 15.2 0.2 0.014 15.2 0.2 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF1980 PF09323.10 OEU13903.1 - 0.067 13.1 1.8 0.12 12.3 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 OEU13903.1 - 0.076 13.1 0.7 0.12 12.5 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PcfK PF14058.6 OEU13903.1 - 0.096 13.0 4.5 0.039 14.2 1.6 1.8 2 0 0 2 2 2 0 PcfK-like protein Spt20 PF12090.8 OEU13903.1 - 0.098 12.3 13.0 0.17 11.5 13.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF4199 PF13858.6 OEU13903.1 - 0.16 12.4 0.2 0.24 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2232 PF09991.9 OEU13903.1 - 0.35 10.0 2.0 0.46 9.6 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) O-antigen_lig PF13425.6 OEU13903.1 - 0.36 9.6 2.4 0.51 9.1 2.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Androgen_recep PF02166.16 OEU13903.1 - 0.59 8.9 5.6 0.95 8.2 5.6 1.3 1 0 0 1 1 1 0 Androgen receptor SID-1_RNA_chan PF13965.6 OEU13903.1 - 0.73 8.2 3.3 1 7.7 3.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 OEU13903.1 - 0.89 8.2 3.5 1.2 7.8 3.5 1.2 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 OEU13903.1 - 2.5 7.0 4.2 3.3 6.6 4.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator His_Phos_1 PF00300.22 OEU13904.1 - 2.6e-22 79.5 0.0 3e-16 59.7 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) IMUP PF15761.5 OEU13905.1 - 0.071 13.8 4.0 0.13 13.0 1.4 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Ion_trans_2 PF07885.16 OEU13906.1 - 0.0012 18.8 6.8 0.021 14.8 7.1 2.5 1 1 1 2 2 2 1 Ion channel MscS_TM PF12794.7 OEU13906.1 - 0.011 14.6 0.2 0.61 8.9 0.0 2.6 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 7TM_GPCR_Srv PF10323.9 OEU13906.1 - 0.11 11.9 2.2 1.9 7.8 0.3 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Pkinase PF00069.25 OEU13907.1 - 1.7e-46 158.7 0.0 2.8e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU13907.1 - 1.3e-28 100.0 0.0 2e-27 96.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OEU13907.1 - 0.00061 18.8 0.0 0.0015 17.6 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OEU13907.1 - 0.0071 16.3 0.2 0.023 14.7 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU13907.1 - 0.032 13.5 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Phage_TAC_12 PF12363.8 OEU13907.1 - 0.14 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC LisH_TPL PF17814.1 OEU13907.1 - 0.15 11.8 1.8 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 LisH-like dimerisation domain Seadorna_VP7 PF07387.11 OEU13907.1 - 0.3 10.1 1.0 1.2 8.1 0.0 2.4 4 0 0 4 4 4 0 Seadornavirus VP7 RVT_1 PF00078.27 OEU13908.1 - 6.2e-08 32.4 0.3 2.4e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU13908.1 - 0.038 14.7 1.7 0.17 12.6 1.7 2.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Mei5_like PF17021.5 OEU13908.1 - 0.93 9.6 5.8 0.26 11.4 0.1 3.2 3 1 1 4 4 4 0 Putative double-strand recombination repair-like Glyco_hydro_99 PF16317.5 OEU13910.1 - 5.3e-12 45.5 2.2 2.5e-07 30.2 0.4 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 99 CBM_35 PF16990.5 OEU13910.1 - 6.4e-05 23.2 0.1 0.00017 21.8 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) B_lectin PF01453.24 OEU13910.1 - 0.00083 19.9 0.1 0.0022 18.5 0.1 1.8 1 0 0 1 1 1 1 D-mannose binding lectin Endotoxin_C PF03944.14 OEU13910.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 delta endotoxin Amino_oxidase PF01593.24 OEU13913.1 - 9.1e-11 41.7 0.0 4.8e-06 26.1 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU13913.1 - 9.8e-07 28.9 0.1 2.4e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU13913.1 - 0.00019 20.8 0.2 0.00052 19.3 0.1 1.7 2 1 1 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OEU13913.1 - 0.035 13.3 0.1 0.081 12.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU13913.1 - 0.039 13.5 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_C2 PF00648.21 OEU13914.1 - 6.1e-38 130.5 0.0 9.4e-37 126.6 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Ribosomal_S21e PF01249.18 OEU13914.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S21e Cys_Met_Meta_PP PF01053.20 OEU13916.1 - 1.1e-120 402.8 0.0 1.7e-120 402.1 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OEU13916.1 - 1.1e-11 44.5 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OEU13916.1 - 7.7e-10 38.3 0.2 1.2e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OEU13916.1 - 1.8e-05 24.2 0.2 3.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 OEU13916.1 - 9.5e-05 21.1 0.0 0.00013 20.6 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase ABC_sub_bind PF04392.12 OEU13916.1 - 0.024 13.9 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein GDC-P PF02347.16 OEU13916.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein ABC1 PF03109.16 OEU13917.1 - 5.6e-18 65.2 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU13917.1 - 1.6e-06 28.3 0.1 9.2e-05 22.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU13917.1 - 0.006 16.0 0.0 0.079 12.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain TPR_10 PF13374.6 OEU13918.1 - 0.014 15.3 0.0 0.048 13.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU13918.1 - 0.054 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Connexin PF00029.19 OEU13918.1 - 0.084 12.6 3.3 0.078 12.7 1.5 1.8 2 0 0 2 2 2 0 Connexin Spore_coat_CotO PF14153.6 OEU13918.1 - 1.2 9.1 9.9 0.7 9.8 3.2 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Kei1 PF08552.11 OEU13918.1 - 7.4 6.4 11.8 0.53 10.1 0.4 3.2 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Lipase_3 PF01764.25 OEU13919.1 - 5.1e-19 68.5 0.0 1.3e-15 57.5 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Esterase PF00756.20 OEU13919.1 - 0.0051 16.5 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase KIP1 PF07765.12 OEU13919.1 - 0.042 14.0 0.5 0.23 11.6 0.5 2.3 1 0 0 1 1 1 0 KIP1-like protein Abhydrolase_6 PF12697.7 OEU13919.1 - 0.05 14.2 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU13919.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU13919.1 - 0.1 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Asp_Arg_Hydrox PF05118.15 OEU13920.1 - 5e-24 84.9 1.6 3.5e-23 82.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase NOA36 PF06524.12 OEU13922.1 - 0.8 9.0 6.0 1.4 8.1 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein NUDIX PF00293.28 OEU13924.1 - 3.6e-09 36.8 0.0 4.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DEP PF00610.21 OEU13925.1 - 9.8e-12 44.8 0.1 2.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Arm PF00514.23 OEU13926.1 - 4.9e-08 32.7 1.1 0.13 12.3 0.0 3.7 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 OEU13926.1 - 0.079 13.0 0.2 4.2 7.5 0.0 2.7 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Exo_endo_phos PF03372.23 OEU13927.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OEU13927.1 - 0.015 15.2 0.5 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase SKG6 PF08693.10 OEU13928.1 - 0.17 11.3 0.8 0.52 9.8 0.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CPBP PF02517.16 OEU13929.1 - 7.7e-13 48.6 5.2 1.4e-12 47.8 5.2 1.4 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease EF-hand_7 PF13499.6 OEU13929.1 - 2e-09 37.7 0.0 3.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU13929.1 - 3.4e-08 32.6 0.1 0.00084 18.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OEU13929.1 - 1.2e-07 30.8 0.0 0.0037 16.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU13929.1 - 1.5e-06 27.7 0.0 0.0021 17.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU13929.1 - 0.00011 22.0 0.1 0.0025 17.6 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU13929.1 - 0.18 12.1 0.1 0.31 11.4 0.1 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SR-25 PF10500.9 OEU13930.1 - 0.00035 20.2 12.7 0.00039 20.1 12.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3558 PF12079.8 OEU13930.1 - 0.068 13.2 5.6 0.086 12.8 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) SAP PF02037.27 OEU13930.1 - 0.1 12.4 0.4 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 SAP domain EBP50_C PF09007.11 OEU13930.1 - 0.29 12.1 9.9 0.38 11.8 9.9 1.3 1 0 0 1 1 1 0 EBP50, C-terminal DNA_pol_phi PF04931.13 OEU13930.1 - 0.38 8.8 10.8 0.45 8.6 10.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 OEU13930.1 - 2.5 6.4 9.1 2.9 6.2 9.1 1.1 1 0 0 1 1 1 0 SGT1 protein Macoilin PF09726.9 OEU13930.1 - 3.1 6.2 10.3 3.4 6.1 10.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 OEU13930.1 - 6.6 6.7 14.1 8.1 6.4 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 OEU13930.1 - 7.2 5.3 12.6 7.4 5.3 12.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 OEU13930.1 - 7.3 5.2 6.3 6.5 5.4 6.3 1.1 1 0 0 1 1 1 0 Presenilin NAM-associated PF14303.6 OEU13930.1 - 8.7 7.0 14.4 3.4 8.4 12.1 1.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Menin PF05053.13 OEU13930.1 - 9.5 4.4 8.3 12 4.2 8.3 1.0 1 0 0 1 1 1 0 Menin MFS_1 PF07690.16 OEU13931.1 - 9.4e-15 54.4 13.8 9.4e-15 54.4 13.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Protocadherin PF08374.11 OEU13931.1 - 0.0032 17.5 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Protocadherin LAB_N PF07578.11 OEU13931.1 - 0.015 15.4 3.0 0.02 15.0 0.7 2.5 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain SARAF PF06682.12 OEU13931.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Helicase_C PF00271.31 OEU13932.1 - 6.1e-09 36.2 0.0 7.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Rhodanese_C PF12368.8 OEU13933.1 - 5e-11 42.8 7.3 1.1e-10 41.7 7.3 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 OEU13933.1 - 1.2e-08 35.2 0.0 3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain RRM_1 PF00076.22 OEU13933.1 - 1.8e-07 30.9 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.20 OEU13933.1 - 2.3e-07 31.3 0.0 5.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DEAD PF00270.29 OEU13934.1 - 9e-34 116.7 0.0 1.1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 OEU13934.1 - 0.012 15.0 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 OEU13934.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3246 PF11596.8 OEU13934.1 - 0.19 11.2 1.8 3.1 7.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Helicase_C PF00271.31 OEU13935.1 - 3.1e-15 56.5 0.0 3.5e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3523 PF12037.8 OEU13936.1 - 5.3e-85 285.0 26.0 1.1e-84 284.0 26.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 OEU13936.1 - 4.9e-22 78.8 0.0 1.2e-21 77.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OEU13936.1 - 6.6e-05 22.7 1.3 0.00016 21.5 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OEU13936.1 - 0.00058 19.9 2.8 0.013 15.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU13936.1 - 0.00095 19.4 3.4 0.013 15.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OEU13936.1 - 0.0028 17.8 0.0 0.0028 17.8 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OEU13936.1 - 0.0032 18.0 2.3 0.064 13.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OEU13936.1 - 0.0038 17.5 0.0 0.0038 17.5 0.0 2.9 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.21 OEU13936.1 - 0.0043 16.5 0.1 0.016 14.6 0.1 2.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OEU13936.1 - 0.0063 16.4 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU13936.1 - 0.0064 16.9 11.7 0.011 16.1 0.0 3.5 2 2 1 3 3 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OEU13936.1 - 0.007 15.7 8.5 0.15 11.4 0.0 3.5 3 1 1 4 4 4 2 FtsK/SpoIIIE family NACHT PF05729.12 OEU13936.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.9 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 OEU13936.1 - 0.025 14.6 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 OEU13936.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OEU13936.1 - 0.063 13.0 0.2 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 OEU13936.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OEU13936.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.9 2 1 0 2 2 1 0 AAA domain Hydin_ADK PF17213.3 OEU13936.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.9 2 1 0 2 2 1 0 Hydin Adenylate kinase-like domain MIIP PF15734.5 OEU13936.1 - 9.5 5.6 12.5 15 5.0 12.5 1.2 1 0 0 1 1 1 0 Migration and invasion-inhibitory SET PF00856.28 OEU13938.1 - 8.4e-13 49.1 0.0 3.1e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 SET domain GHMP_kinases_N PF00288.26 OEU13939.1 - 1.4e-12 47.6 1.2 1.4e-12 47.6 1.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OEU13939.1 - 1.7e-08 34.7 0.0 5e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF515 PF04415.12 OEU13939.1 - 0.0061 15.0 1.1 0.0097 14.3 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF515) Thg1 PF04446.12 OEU13939.1 - 0.15 12.1 0.2 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 tRNAHis guanylyltransferase PT PF04886.12 OEU13940.1 - 5e-10 38.7 129.9 0.00015 21.2 9.9 9.5 3 1 3 6 6 6 2 PT repeat HAD_2 PF13419.6 OEU13941.1 - 2.7e-20 73.2 0.0 1.2e-19 71.0 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU13941.1 - 2.5e-13 50.8 0.1 2.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU13941.1 - 1.2e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like GMC_oxred_C PF05199.13 OEU13942.1 - 3.3e-09 37.4 0.0 5.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OEU13942.1 - 4.2e-06 26.4 0.3 0.036 13.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 OEU13942.1 - 0.042 13.1 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU13942.1 - 0.051 14.1 1.6 1e+02 3.5 0.1 4.5 5 0 0 5 5 5 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 OEU13943.1 - 0.011 15.3 0.1 0.038 13.6 0.1 2.0 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 OEU13943.1 - 0.025 14.1 2.4 0.029 13.9 0.6 2.0 2 0 0 2 2 2 0 EF hand EphA2_TM PF14575.6 OEU13943.1 - 0.036 14.9 0.3 0.22 12.4 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain EF-hand_8 PF13833.6 OEU13943.1 - 0.058 13.2 0.4 0.2 11.5 0.4 2.0 1 0 0 1 1 1 0 EF-hand domain pair GFO_IDH_MocA PF01408.22 OEU13945.1 - 0.00036 21.3 0.0 0.001 19.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DUF5005 PF16396.5 OEU13945.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) DUF4094 PF13334.6 OEU13946.1 - 0.23 11.9 0.9 0.28 11.6 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) CLZ PF16526.5 OEU13948.1 - 0.043 14.2 0.4 12 6.3 0.1 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PGK PF00162.19 OEU13949.1 - 1.9e-150 501.0 2.8 2.2e-150 500.8 2.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase CxxCxxCC PF03692.15 OEU13951.1 - 0.1 13.3 0.7 1.2 9.9 0.1 2.7 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain FAD_binding_3 PF01494.19 OEU13953.1 - 2.7e-12 46.6 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OEU13953.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OEU13953.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OEU13953.1 - 0.036 13.3 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU13953.1 - 0.038 12.7 0.0 0.067 11.9 0.0 1.5 1 1 0 1 1 1 0 HI0933-like protein DAO PF01266.24 OEU13953.1 - 0.1 12.1 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OEU13953.1 - 0.23 10.5 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TAF1D PF15333.6 OEU13955.1 - 0.68 9.6 8.4 0.18 11.5 5.5 1.5 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Zip PF02535.22 OEU13955.1 - 0.87 8.7 3.0 0.98 8.6 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.12 OEU13955.1 - 5.2 4.9 13.4 6.6 4.6 13.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.9 OEU13955.1 - 6.1 6.4 20.5 0.03 14.0 11.9 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Coatomer_E PF04733.14 OEU13956.1 - 1.5e-54 185.4 0.3 1.8e-54 185.2 0.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 OEU13956.1 - 9.4e-07 29.2 9.0 0.26 11.8 0.1 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU13956.1 - 0.0016 18.4 4.2 0.1 12.8 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OEU13956.1 - 0.032 14.2 0.2 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 OEU13956.1 - 0.09 13.6 2.7 64 4.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU13956.1 - 0.39 10.8 2.6 1 9.5 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13956.1 - 0.71 9.8 5.5 30 4.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 OEU13958.1 - 2.6e-11 42.8 0.0 4.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OEU13958.1 - 0.0002 22.2 0.0 0.00038 21.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S8 PF00082.22 OEU13959.1 - 3.3e-65 220.3 0.1 5.5e-65 219.6 0.1 1.4 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 OEU13959.1 - 8.2e-46 155.9 0.0 1.8e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Tripeptidyl peptidase II DUF5401 PF17380.2 OEU13959.1 - 0.65 8.0 6.5 1.1 7.2 6.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4363 PF14276.6 OEU13960.1 - 0.1 12.7 0.5 0.25 11.5 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) GAS PF13851.6 OEU13961.1 - 0.0026 17.2 13.3 0.0026 17.2 13.3 13.5 5 2 5 13 13 13 5 Growth-arrest specific micro-tubule binding Mito_carr PF00153.27 OEU13962.1 - 1.7e-05 24.6 0.1 4.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein Anthrax_toxA PF03497.16 OEU13963.1 - 0.0012 19.0 0.1 0.01 15.9 0.1 2.2 2 0 0 2 2 2 1 Anthrax toxin LF subunit Biopterin_H PF00351.21 OEU13965.1 - 3.2e-133 443.9 0.5 4.1e-133 443.5 0.5 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 OEU13965.1 - 2.8e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF2623 PF11115.8 OEU13965.1 - 0.064 13.3 0.1 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) HA PF03457.14 OEU13966.1 - 9.6e-26 89.9 3.5 3.7e-15 56.0 0.1 2.5 2 0 0 2 2 2 2 Helicase associated domain DUF5613 PF18467.1 OEU13966.1 - 0.041 14.3 1.3 0.3 11.5 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5613) WIYLD PF10440.9 OEU13967.1 - 0.048 13.5 0.4 0.089 12.6 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_6 PF13921.6 OEU13967.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rhodanese_C PF12368.8 OEU13969.1 - 2e-12 47.3 4.3 8.3e-12 45.3 4.3 2.2 1 1 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 OEU13969.1 - 1.5e-07 31.7 0.0 3.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OEU13969.1 - 1.6e-05 25.4 0.0 0.0001 22.8 0.0 2.5 3 1 0 3 3 3 1 Rhodanese-like domain zf-CCCH_2 PF14608.6 OEU13969.1 - 0.12 12.8 2.9 0.37 11.4 2.9 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FYVE PF01363.21 OEU13969.1 - 1.8 8.8 9.1 5.1 7.3 9.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger Methyltransf_16 PF10294.9 OEU13970.1 - 5.8e-18 65.2 0.2 8.7e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OEU13970.1 - 1.3e-08 34.6 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OEU13970.1 - 0.00015 22.4 0.0 0.00026 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU13970.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OEU13970.1 - 0.018 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OEU13970.1 - 0.06 14.0 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OEU13970.1 - 0.13 13.0 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 OEU13970.1 - 0.14 12.1 0.0 0.59 10.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ABC_membrane PF00664.23 OEU13971.1 - 2.2e-34 119.4 0.3 4.1e-34 118.5 0.3 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OEU13971.1 - 5.9e-27 94.8 0.0 1.5e-26 93.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU13971.1 - 1.2e-08 34.7 1.5 4.9e-07 29.4 0.1 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU13971.1 - 0.0024 18.2 0.0 0.011 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OEU13971.1 - 0.0042 16.8 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OEU13971.1 - 0.0043 16.9 0.0 0.046 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OEU13971.1 - 0.01 16.3 0.4 0.036 14.5 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 OEU13971.1 - 0.011 15.3 0.0 0.036 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain TMF_DNA_bd PF12329.8 OEU13971.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lipase_GDSL_3 PF14606.6 OEU13971.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AAA_18 PF13238.6 OEU13971.1 - 0.047 14.2 0.1 0.14 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OEU13971.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Asp2 PF16929.5 OEU13972.1 - 0.013 14.5 1.5 0.015 14.3 1.5 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter DUF1690 PF07956.11 OEU13972.1 - 0.11 12.9 4.7 0.19 12.1 3.7 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Mod_r PF07200.13 OEU13972.1 - 0.21 11.7 5.6 0.23 11.5 1.4 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nup54 PF13874.6 OEU13972.1 - 1.2 9.2 8.8 6 7.0 4.3 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SRP72 PF08492.12 OEU13973.1 - 3.8 8.0 10.4 2.7 8.5 4.2 2.8 3 0 0 3 3 3 0 SRP72 RNA-binding domain SPT6_acidic PF14632.6 OEU13973.1 - 5.1 7.7 12.8 11 6.7 3.0 3.0 3 0 0 3 3 3 0 Acidic N-terminal SPT6 SAE2 PF08573.10 OEU13974.1 - 9.4e-05 23.5 4.1 0.003 18.6 0.5 9.5 7 4 1 9 9 9 2 DNA repair protein endonuclease SAE2/CtIP C-terminus HMG_CoA_synt_C PF08540.10 OEU13975.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Cons_hypoth698 PF03601.14 OEU13975.1 - 0.18 10.6 3.8 0.24 10.2 3.8 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 698 WD40 PF00400.32 OEU13977.1 - 6.4e-65 213.5 15.5 2.7e-09 37.5 0.0 9.2 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU13977.1 - 1.1e-23 83.3 1.4 0.001 19.3 0.0 6.9 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU13977.1 - 1.1e-09 37.7 0.3 0.032 13.2 0.0 5.7 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OEU13977.1 - 1.8e-09 37.8 0.2 0.009 15.9 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OEU13977.1 - 5.4e-06 26.2 4.1 1.2 9.1 0.0 5.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 OEU13977.1 - 9.4e-06 25.2 0.1 1.1 8.5 0.0 4.2 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 OEU13977.1 - 0.00011 20.9 0.7 0.25 9.8 0.0 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 OEU13977.1 - 0.00012 21.6 0.0 2.2 7.6 0.0 4.0 4 0 0 4 4 4 1 WD40-like domain NLE PF08154.12 OEU13977.1 - 0.00067 20.1 0.1 0.0012 19.3 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain nos_propeller PF18764.1 OEU13977.1 - 0.0038 17.1 0.7 23 5.0 0.0 4.2 4 0 0 4 4 4 0 Nitrous oxide reductase propeller repeat Proteasome_A_N PF10584.9 OEU13977.1 - 0.0046 16.6 2.7 4.8 7.0 0.0 4.4 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature Nup160 PF11715.8 OEU13977.1 - 0.041 12.5 0.7 7.6 5.0 0.0 3.4 3 2 2 5 5 5 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OEU13977.1 - 0.082 11.8 1.1 39 3.0 0.1 3.8 2 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain TFIIIC_delta PF12657.7 OEU13977.1 - 0.15 12.0 2.3 5.1 7.0 0.0 3.5 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term AIM24 PF01987.17 OEU13978.1 - 1.5e-58 197.9 0.6 1.8e-58 197.7 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Glycos_transf_1 PF00534.20 OEU13979.1 - 5.2e-21 74.9 0.0 8.1e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU13979.1 - 1.2e-20 74.3 0.0 2.9e-20 73.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OEU13979.1 - 1.5e-11 44.6 0.8 5.8e-11 42.7 0.8 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OEU13979.1 - 0.00036 21.0 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OEU13979.1 - 0.013 15.8 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 PrmA PF06325.13 OEU13980.1 - 3.3e-11 43.1 0.0 5.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OEU13980.1 - 4.6e-10 40.1 0.0 1.2e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU13980.1 - 3.1e-08 33.6 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU13980.1 - 1.3e-07 32.2 0.1 4.6e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU13980.1 - 9.6e-07 28.8 0.0 1.6e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU13980.1 - 5.5e-05 22.8 0.1 8.8e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 OEU13980.1 - 0.0016 17.4 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 OEU13980.1 - 0.0027 18.4 0.0 0.0054 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 OEU13980.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 OEU13980.1 - 0.0087 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 OEU13980.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 PRMT5 oligomerisation domain TehB PF03848.14 OEU13980.1 - 0.034 13.6 0.6 0.13 11.6 0.5 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 OEU13980.1 - 0.047 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OEU13980.1 - 0.096 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MIG-14_Wnt-bd PF06664.12 OEU13981.1 - 0.00046 19.5 0.7 0.0009 18.5 0.7 1.4 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion bZIP_Maf PF03131.17 OEU13981.1 - 0.63 10.6 0.1 0.63 10.6 0.1 2.8 2 1 0 2 2 2 0 bZIP Maf transcription factor DUF4407 PF14362.6 OEU13981.1 - 6.9 5.9 9.4 12 5.2 8.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) STE2 PF02116.15 OEU13982.1 - 0.047 13.0 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DUF2569 PF10754.9 OEU13982.1 - 0.064 13.7 1.3 6.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) dbPDZ_assoc PF16610.5 OEU13982.1 - 0.093 13.0 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 DUF267 PF03268.14 OEU13982.1 - 0.16 10.8 3.0 3.8 6.3 0.4 2.1 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 DUF1240 PF06836.12 OEU13982.1 - 0.99 10.0 0.1 0.99 10.0 0.1 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1240) DHHC PF01529.20 OEU13982.1 - 1.1 9.4 4.6 1.9 8.6 1.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Metallophos PF00149.28 OEU13983.1 - 7.3e-25 88.7 0.0 1.6e-24 87.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OEU13983.1 - 2.6e-19 69.4 1.6 5e-19 68.5 0.9 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF316 PF03761.15 OEU13983.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 DUF3903 PF13043.6 OEU13983.1 - 0.15 11.9 0.2 0.33 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) ATP-synt_ab PF00006.25 OEU13984.1 - 7.6e-07 29.0 0.3 2.3e-06 27.4 0.3 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3130 PF11328.8 OEU13984.1 - 0.024 14.9 0.9 0.049 13.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Mito_carr PF00153.27 OEU13986.1 - 8.8e-09 35.2 0.1 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein LolB PF03550.14 OEU13986.1 - 0.00016 21.7 0.2 0.0002 21.4 0.2 1.3 1 1 0 1 1 1 1 Outer membrane lipoprotein LolB tRNA-synt_1 PF00133.22 OEU13987.1 - 3.5e-173 577.1 0.1 1.8e-126 422.9 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OEU13987.1 - 5e-30 104.5 0.0 9.6e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OEU13987.1 - 2.3e-13 49.7 0.0 2.6e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OEU13987.1 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OEU13987.1 - 0.018 14.4 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Bromodomain PF00439.25 OEU13988.1 - 9.3e-19 67.3 0.0 9.9e-19 67.2 0.0 1.0 1 0 0 1 1 1 1 Bromodomain MADF_DNA_bdg PF10545.9 OEU13989.1 - 0.31 11.4 10.1 3.5 8.0 1.7 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LEA_6 PF10714.9 OEU13989.1 - 3.9 7.6 6.7 14 5.8 6.7 2.0 1 1 0 1 1 1 0 Late embryogenesis abundant protein 18 LRR_6 PF13516.6 OEU13991.1 - 3.1e-08 33.0 10.8 0.12 12.5 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 OEU13991.1 - 1.1e-06 28.9 17.0 0.047 14.1 0.1 5.7 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU13991.1 - 5.8e-05 22.8 14.3 9.5e-05 22.1 0.1 4.5 5 0 0 5 5 5 2 Leucine rich repeat Gal_Lectin PF02140.18 OEU13991.1 - 0.0017 18.7 0.4 0.027 14.9 0.0 3.0 2 1 0 2 2 2 1 Galactose binding lectin domain F-box-like PF12937.7 OEU13991.1 - 0.13 12.2 1.7 0.96 9.4 0.9 2.4 2 0 0 2 2 2 0 F-box-like TPR_2 PF07719.17 OEU13993.1 - 2.1e-06 27.4 0.7 0.15 12.3 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU13993.1 - 2.7e-06 27.1 2.0 0.033 14.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU13993.1 - 0.0002 21.5 0.0 0.68 10.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU13993.1 - 0.0007 19.8 1.4 0.034 14.4 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU13993.1 - 0.0013 18.4 3.6 0.36 10.7 0.2 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU13993.1 - 0.0072 16.0 0.2 5.8 6.7 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 OEU13993.1 - 0.091 13.4 0.2 5.9 7.6 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OEU13993.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.6 OEU13993.1 - 0.22 10.9 1.3 4.2 6.7 0.4 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Cwf_Cwc_15 PF04889.12 OEU13993.1 - 0.61 9.8 13.3 1.3 8.7 2.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ANAPC15 PF15243.6 OEU13993.1 - 1.8 9.0 15.4 3.1 8.3 2.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 eIF_4EBP PF05456.11 OEU13993.1 - 2.9 7.8 5.5 11 6.0 1.8 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CENP-B_dimeris PF09026.10 OEU13993.1 - 3 8.3 15.1 0.38 11.2 3.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.32 OEU13994.1 - 1.9e-11 44.3 2.4 0.00084 20.1 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat RVT_3 PF13456.6 OEU13995.1 - 8e-11 41.8 0.0 2e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 OEU13995.1 - 9.8e-08 32.3 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 RNase H DUF16 PF01519.16 OEU13996.1 - 0.013 16.0 0.8 0.013 16.0 0.8 3.7 4 0 0 4 4 4 0 Protein of unknown function DUF16 VasI PF11319.8 OEU13996.1 - 2.9 7.5 6.8 0.41 10.3 0.4 2.7 3 0 0 3 3 3 0 Type VI secretion system VasI, EvfG, VC_A0118 TSC22 PF01166.18 OEU13997.1 - 0.12 12.7 0.2 0.12 12.7 0.2 3.6 4 0 0 4 4 4 0 TSC-22/dip/bun family Epimerase PF01370.21 OEU13999.1 - 3.2e-12 46.4 0.0 1.5e-10 41.0 0.0 2.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OEU13999.1 - 3e-10 39.7 0.0 8.6e-07 28.3 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 OEU13999.1 - 7.4e-08 31.7 0.1 7.6e-05 21.9 0.2 2.6 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OEU13999.1 - 8.2e-08 32.4 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OEU13999.1 - 0.00064 19.2 0.0 0.014 14.8 0.1 2.1 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OEU13999.1 - 0.00068 18.9 0.4 3.6 6.7 0.0 2.9 2 1 1 3 3 3 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 OEU13999.1 - 0.02 15.2 0.0 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 OEU13999.1 - 0.029 14.5 0.1 0.088 12.9 0.1 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 OEU13999.1 - 0.032 13.8 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 NmrA-like family zf-MYND PF01753.18 OEU14000.1 - 3.9e-08 33.2 19.8 3.9e-08 33.2 19.8 2.0 2 1 0 2 2 2 1 MYND finger Glyco_hydro_88 PF07470.13 OEU14000.1 - 0.31 10.1 2.7 1.5 7.8 0.0 2.5 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 DAO PF01266.24 OEU14001.1 - 1.1e-16 61.4 0.1 1.9e-16 60.6 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DLH PF01738.18 OEU14001.1 - 3e-16 59.6 0.0 1.1e-13 51.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Pyr_redox PF00070.27 OEU14001.1 - 0.00048 20.6 0.3 0.0029 18.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OEU14001.1 - 0.0013 18.0 0.1 0.0044 16.3 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU14001.1 - 0.0046 17.2 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU14001.1 - 0.01 15.1 0.6 0.019 14.2 0.6 1.3 1 0 0 1 1 1 0 Thi4 family Abhydrolase_3 PF07859.13 OEU14001.1 - 0.017 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PA PF02225.22 OEU14002.1 - 2.4e-09 37.1 0.0 6.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PA domain MUG113 PF13455.6 OEU14003.1 - 0.43 11.3 3.4 0.39 11.4 2.0 1.7 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Pet191_N PF10203.9 OEU14003.1 - 0.99 9.8 10.3 3.5 8.0 2.6 2.5 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF1517 PF07466.11 OEU14004.1 - 4.7e-35 121.4 0.0 5.4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) PA PF02225.22 OEU14005.1 - 1.4e-06 28.2 0.0 5.3e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 PA domain DUF3213 PF11491.8 OEU14006.1 - 0.022 15.0 0.4 0.022 15.0 0.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3213) CENP-K PF11802.8 OEU14006.1 - 1 8.9 17.7 1.6 8.2 17.7 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF2203 PF09969.9 OEU14006.1 - 2.1 9.1 11.9 0.84 10.4 1.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YtxH PF12732.7 OEU14006.1 - 2.2 8.9 6.2 7.5 7.2 6.2 2.0 1 1 0 1 1 1 0 YtxH-like protein Fmp27_WPPW PF10359.9 OEU14006.1 - 3.4 6.4 17.9 5.9 5.6 17.7 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 OEU14006.1 - 7.1 5.8 13.2 2.6 7.2 10.5 1.5 1 1 1 2 2 2 0 TMPIT-like protein AAA_14 PF13173.6 OEU14007.1 - 0.00013 22.0 0.0 0.00048 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OEU14007.1 - 0.065 12.8 0.0 0.21 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OEU14007.1 - 0.091 12.2 4.1 0.88 9.0 0.0 3.3 4 1 0 4 4 4 0 Signal recognition particle receptor beta subunit Spt20 PF12090.8 OEU14007.1 - 0.89 9.1 35.5 0.19 11.3 14.1 3.6 4 0 0 4 4 4 0 Spt20 family CSG2 PF16965.5 OEU14007.1 - 4.3 6.2 10.1 0.2 10.5 3.5 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Ureide_permease PF07168.11 OEU14007.1 - 7.1 5.3 7.6 20 3.8 2.9 2.4 2 0 0 2 2 2 0 Ureide permease Caa3_CtaG PF09678.10 OEU14008.1 - 0.054 12.9 0.0 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) PDZ_6 PF17820.1 OEU14009.1 - 2.9e-07 30.2 0.0 5.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU14009.1 - 0.0018 18.6 0.8 0.0033 17.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 OEU14009.1 - 0.0071 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Abhydrolase_1 PF00561.20 OEU14010.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU14010.1 - 0.0001 23.0 0.0 0.00015 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU14010.1 - 0.0064 15.8 0.0 4.1 6.6 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 TP6A_N PF04406.14 OEU14011.1 - 4.6e-10 39.3 0.3 6.4e-09 35.7 0.3 2.4 2 0 0 2 2 2 1 Type IIB DNA topoisomerase RNF220 PF15926.5 OEU14011.1 - 0.035 13.7 0.4 0.035 13.7 0.4 3.6 3 1 0 4 4 4 0 E3 ubiquitin-protein ligase RNF220 SR-25 PF10500.9 OEU14011.1 - 4.9 6.7 34.5 0.45 10.1 13.9 3.8 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Aldo_ket_red PF00248.21 OEU14012.1 - 2.6e-49 168.0 0.0 4.9e-49 167.1 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family CAF1C_H4-bd PF12265.8 OEU14013.1 - 2.7e-26 91.6 0.2 2.5e-25 88.5 0.2 2.5 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OEU14013.1 - 2.4e-23 82.0 15.0 1.9e-05 25.3 0.3 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Helicase_C PF00271.31 OEU14014.1 - 6.5e-11 42.6 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU14014.1 - 0.00016 21.5 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase zf-CSL PF05207.13 OEU14015.1 - 1.3e-20 72.8 1.8 1.5e-20 72.6 1.8 1.1 1 0 0 1 1 1 1 CSL zinc finger eIF-5a PF01287.20 OEU14016.1 - 1.3e-15 57.3 0.1 1.8e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OEU14016.1 - 0.00019 21.4 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Pantoate_transf PF02548.15 OEU14017.1 - 3.5e-99 331.4 0.6 5e-99 330.9 0.6 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 OEU14017.1 - 0.0019 18.1 0.1 0.0037 17.1 0.1 1.6 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase PEP_mutase PF13714.6 OEU14017.1 - 0.0036 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ubie_methyltran PF01209.18 OEU14017.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DNA_photolyase PF00875.18 OEU14018.1 - 2.4e-18 66.7 0.2 4e-18 66.0 0.2 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 OEU14018.1 - 0.18 12.3 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family Rdx PF10262.9 OEU14020.1 - 0.00074 19.7 0.0 0.0012 19.0 0.0 1.3 1 1 0 1 1 1 1 Rdx family PDEase_I_N PF08499.12 OEU14020.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Nucleoporin_N PF08801.11 OEU14023.1 - 3.5e-26 92.0 8.3 5.8e-13 48.4 0.2 3.3 2 2 0 2 2 2 2 Nup133 N terminal like Nucleoporin_C PF03177.14 OEU14023.1 - 1.8e-14 53.4 0.0 1.1e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal TetR_C_29 PF17938.1 OEU14023.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain EXS PF03124.14 OEU14024.1 - 1.1e-63 215.6 19.2 1.5e-63 215.2 19.2 1.2 1 0 0 1 1 1 1 EXS family TED_complement PF07678.14 OEU14024.1 - 0.051 12.6 0.3 0.082 11.9 0.3 1.2 1 0 0 1 1 1 0 A-macroglobulin TED domain KASH PF10541.9 OEU14024.1 - 2.7 8.3 10.4 2.1 8.7 0.3 4.5 5 0 0 5 5 5 0 Nuclear envelope localisation domain dCMP_cyt_deam_1 PF00383.23 OEU14025.1 - 4.1e-10 39.4 0.0 7.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OEU14025.1 - 0.0002 21.1 0.1 0.00056 19.7 0.1 1.9 1 1 0 1 1 1 1 MafB19-like deaminase ADK PF00406.22 OEU14026.1 - 3.2e-49 166.9 0.0 4.2e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU14026.1 - 5.6e-26 91.6 0.4 1.2e-25 90.5 0.0 1.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 OEU14026.1 - 2.6e-09 37.7 0.0 6.8e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 OEU14026.1 - 2.2e-05 24.9 4.3 0.0025 18.1 0.1 2.6 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 OEU14026.1 - 0.0016 17.8 0.0 0.0036 16.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.18 OEU14026.1 - 0.004 16.9 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase AAA_33 PF13671.6 OEU14026.1 - 0.0045 17.2 0.1 0.038 14.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OEU14026.1 - 0.016 14.9 0.1 3.3 7.4 0.0 2.9 2 1 0 3 3 3 0 Thymidylate kinase ADK_lid PF05191.14 OEU14026.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid dNK PF01712.19 OEU14026.1 - 0.034 14.0 0.5 25 4.6 0.1 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase TPP_enzyme_N PF02776.18 OEU14027.1 - 6.2e-39 133.4 0.5 1.2e-38 132.5 0.5 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OEU14027.1 - 2.7e-23 82.5 0.0 1.2e-22 80.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OEU14027.1 - 5.6e-14 52.1 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain HEAT_2 PF13646.6 OEU14028.1 - 8.9e-18 64.5 0.3 1e-08 35.4 0.0 2.4 2 0 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 OEU14028.1 - 1.8e-12 46.7 0.0 0.22 12.3 0.0 4.6 4 0 0 4 4 4 4 PBS lyase HEAT-like repeat HEAT PF02985.22 OEU14028.1 - 0.00023 21.1 0.1 2.1 8.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 OEU14028.1 - 0.046 14.2 0.2 20 5.8 0.0 3.0 2 1 0 2 2 2 0 HEAT-like repeat TPD PF14811.6 OEU14029.1 - 5.1e-25 87.9 0.1 6.6e-25 87.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif PDDEXK_3 PF13366.6 OEU14029.1 - 9.4e-05 22.8 0.2 0.00027 21.3 0.0 2.0 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily EamA PF00892.20 OEU14031.1 - 1.2e-05 25.5 0.0 1.2e-05 25.5 0.0 3.7 4 1 0 4 4 4 1 EamA-like transporter family Tetraspanin PF00335.20 OEU14031.1 - 0.51 10.0 8.3 5.5 6.6 0.0 3.6 2 1 1 3 3 3 0 Tetraspanin family TMEM252 PF15664.5 OEU14031.1 - 0.64 9.7 2.9 3.2 7.5 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 252 family TMEM51 PF15345.6 OEU14031.1 - 1.9 8.3 0.0 1.9 8.3 0.0 2.5 3 0 0 3 3 3 0 Transmembrane protein 51 FlgM PF04316.13 OEU14032.1 - 0.029 14.7 0.3 0.12 12.8 0.3 2.0 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Met_asp_mut_E PF06368.11 OEU14032.1 - 0.079 11.4 0.6 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) Aminotran_5 PF00266.19 OEU14033.1 - 4.7e-25 88.3 0.0 2.7e-13 49.6 0.0 3.1 3 0 0 3 3 3 2 Aminotransferase class-V ATP_bind_3 PF01171.20 OEU14033.1 - 2.5e-14 53.4 0.0 6.9e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 PP-loop family HA PF03457.14 OEU14034.1 - 3.9e-130 424.3 26.5 6.2e-22 77.7 0.8 9.4 7 3 0 7 7 7 7 Helicase associated domain TAN PF11640.8 OEU14034.1 - 0.62 10.2 3.2 21 5.2 0.0 3.6 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair FKBP_C PF00254.28 OEU14035.1 - 8e-14 51.7 0.0 9.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Syntaxin PF00804.25 OEU14036.1 - 7.1e-32 110.7 11.4 9.8e-32 110.3 11.4 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 OEU14036.1 - 6.6e-12 45.2 0.6 2e-11 43.7 0.6 1.9 1 0 0 1 1 1 1 SNARE domain Pepsin-I3 PF06394.13 OEU14036.1 - 0.011 15.9 1.0 0.011 15.9 1.0 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Syntaxin_2 PF14523.6 OEU14036.1 - 0.1 13.0 14.5 0.048 14.0 10.0 2.4 2 1 0 2 2 2 0 Syntaxin-like protein KIP1 PF07765.12 OEU14036.1 - 0.22 11.7 3.4 6.7 6.9 0.3 2.9 2 0 0 2 2 2 0 KIP1-like protein IL15 PF02372.15 OEU14036.1 - 2.9 7.9 8.1 5 7.1 2.2 2.5 2 1 0 2 2 2 0 Interleukin 15 Ank_2 PF12796.7 OEU14037.1 - 3.6e-22 78.7 0.1 1.4e-12 48.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU14037.1 - 1e-19 68.5 0.1 0.0001 22.4 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OEU14037.1 - 1.5e-19 69.7 0.2 1.2e-05 25.5 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU14037.1 - 1.3e-18 66.5 1.0 0.00034 20.9 0.1 4.8 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OEU14037.1 - 7e-18 64.7 0.2 3.3e-08 33.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PTS_IIA PF02255.16 OEU14037.1 - 0.011 15.8 0.1 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Pep_deformylase PF01327.21 OEU14038.1 - 1.1e-50 171.4 0.0 1.5e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase CbiX PF01903.17 OEU14039.1 - 1.6e-16 60.5 0.0 1.8e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 OEU14039.1 - 0.00069 19.0 0.0 0.00082 18.8 0.0 1.0 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) GUN4 PF05419.12 OEU14041.1 - 2.6e-44 150.7 0.0 3e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 GUN4-like TLC PF03219.14 OEU14042.1 - 3.7e-186 619.6 13.3 4.6e-186 619.3 13.3 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter SSURE PF11966.8 OEU14042.1 - 0.038 13.7 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Fibronectin-binding repeat Peptidase_M48_N PF16491.5 OEU14042.1 - 1.2 9.0 8.8 0.14 12.0 0.4 3.0 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices WD40_4 PF16300.5 OEU14043.1 - 1.2e-15 57.1 0.0 2.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 OEU14043.1 - 4.9e-14 51.9 0.0 8.6e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 OEU14043.1 - 1.6e-10 41.4 3.7 0.007 17.2 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 OEU14043.1 - 3.7e-05 22.6 0.2 0.00085 18.1 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OEU14043.1 - 4.4e-05 23.7 0.1 4.1 7.8 0.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Acyltransferase PF01553.21 OEU14044.1 - 2.9e-26 91.7 0.0 4.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Tic22 PF04278.12 OEU14045.1 - 0.017 14.5 0.0 1.9 7.8 0.0 2.1 1 1 0 2 2 2 0 Tic22-like family PGAP1 PF07819.13 OEU14046.1 - 5.1e-07 29.6 0.0 1.9e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OEU14046.1 - 3.7e-06 26.6 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OEU14046.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 OEU14046.1 - 0.0045 17.6 0.0 0.013 16.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family BCDHK_Adom3 PF10436.9 OEU14047.1 - 3e-24 85.7 0.0 4.4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OEU14047.1 - 4.4e-09 36.8 0.0 8.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OEU14047.1 - 9.9e-06 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0126 PF03458.13 OEU14048.1 - 8.3e-39 131.3 16.4 3.1e-21 75.1 5.3 2.0 2 0 0 2 2 2 2 UPF0126 domain TMEM135_C_rich PF15982.5 OEU14048.1 - 0.058 14.0 0.2 0.073 13.7 0.2 1.2 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 Tox-SHH PF15652.6 OEU14050.1 - 0.74 10.8 4.2 0.73 10.8 0.7 2.3 1 1 1 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature DUF148 PF02520.17 OEU14050.1 - 0.91 9.7 16.5 1 9.5 4.9 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF148 MBOAT PF03062.19 OEU14051.1 - 7.9e-21 74.8 21.3 7.9e-21 74.8 21.3 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OEU14051.1 - 0.0048 17.1 6.4 0.0048 17.1 6.4 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF4209 PF13910.6 OEU14052.1 - 6.2e-11 42.4 0.4 4.4e-05 23.6 0.6 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) PAC3 PF10178.9 OEU14053.1 - 0.013 15.6 0.4 6.3 7.0 0.1 2.3 1 1 1 2 2 2 0 Proteasome assembly chaperone 3 vATP-synt_E PF01991.18 OEU14053.1 - 0.057 12.8 4.7 0.075 12.4 4.7 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Cyclin_N PF00134.23 OEU14054.1 - 2.1e-11 43.6 2.6 2.1e-11 43.6 2.6 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain ExbD PF02472.16 OEU14054.1 - 0.07 13.3 4.2 0.23 11.6 4.2 1.9 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR BUD22 PF09073.10 OEU14054.1 - 2.8 7.2 23.6 0.094 12.0 11.0 2.1 2 0 0 2 2 2 0 BUD22 Peptidase_M48 PF01435.18 OEU14055.1 - 1.4e-19 70.7 0.7 2.4e-11 43.8 0.1 3.0 1 1 1 2 2 2 2 Peptidase family M48 Peptidase_M56 PF05569.11 OEU14055.1 - 0.00034 19.9 0.0 0.00058 19.1 0.0 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 Aromatic_hydrox PF11723.8 OEU14055.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase BaxI_1 PF12811.7 OEU14056.1 - 0.012 15.2 0.6 0.015 14.9 0.6 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like TFIIE_alpha PF02002.17 OEU14057.1 - 1.8e-14 53.5 0.0 4.3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit AAA_17 PF13207.6 OEU14057.1 - 0.083 13.3 2.9 0.51 10.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain zf-C4_ClpX PF06689.13 OEU14057.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger Dicty_REP PF05086.12 OEU14057.1 - 0.52 8.2 4.6 0.7 7.8 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ABC2_membrane PF01061.24 OEU14058.1 - 7.8e-33 113.7 21.8 7.8e-33 113.7 21.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OEU14058.1 - 1.1e-28 100.5 0.0 4.6e-28 98.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 OEU14058.1 - 8.3e-09 35.0 12.8 1.5e-08 34.1 12.8 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 OEU14058.1 - 1.1e-05 25.1 1.0 0.0017 17.8 0.6 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU14058.1 - 1.4e-05 25.1 0.8 0.046 13.5 0.0 2.6 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU14058.1 - 0.0018 18.2 0.2 0.0056 16.6 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OEU14058.1 - 0.002 18.6 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OEU14058.1 - 0.066 13.7 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OEU14058.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 OEU14058.1 - 0.16 12.1 1.1 0.53 10.3 1.1 1.9 1 1 0 1 1 1 0 Dynamin family ECF_trnsprt PF12822.7 OEU14058.1 - 1.8 8.6 10.1 6.4 6.9 10.1 1.9 1 1 0 1 1 1 0 ECF transporter, substrate-specific component LRR_6 PF13516.6 OEU14060.1 - 4e-06 26.4 19.3 0.0019 18.1 0.3 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 OEU14060.1 - 0.00059 20.2 23.9 0.0015 18.9 3.4 4.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 OEU14060.1 - 0.0042 17.7 6.5 0.66 10.7 0.4 3.6 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.6 OEU14060.1 - 0.097 12.4 19.5 0.92 9.3 4.2 4.4 2 1 2 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 OEU14060.1 - 0.35 11.6 9.5 43 5.2 0.1 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat Got1 PF04178.12 OEU14061.1 - 1.1e-25 90.2 9.6 1.7e-25 89.7 9.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family TB2_DP1_HVA22 PF03134.19 OEU14061.1 - 1.7 8.6 9.5 0.14 12.1 3.8 1.9 2 0 0 2 2 2 0 TB2/DP1, HVA22 family LTV PF04180.14 OEU14062.1 - 0.0075 16.1 0.3 0.017 14.9 0.3 1.5 1 1 0 1 1 1 1 Low temperature viability protein IMUP PF15761.5 OEU14063.1 - 0.59 10.8 19.7 0.1 13.3 6.6 3.0 2 1 1 3 3 3 0 Immortalisation up-regulated protein Ank_4 PF13637.6 OEU14064.1 - 0.13 12.9 0.0 41 4.9 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Sigma70_ner PF04546.13 OEU14064.1 - 3.8 7.4 14.3 0.83 9.5 10.0 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region SEEEED PF14797.6 OEU14064.1 - 3.8 7.7 35.4 0.16 12.1 13.4 2.4 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex YL1 PF05764.13 OEU14064.1 - 6.4 6.8 19.9 7.6 6.6 11.5 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Nab1 PF04902.12 OEU14065.1 - 0.059 13.8 0.1 0.084 13.3 0.1 1.4 1 1 0 1 1 1 0 Conserved region in Nab1 UBX PF00789.20 OEU14066.1 - 0.00065 19.9 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.14 OEU14066.1 - 0.17 11.0 9.9 0.23 10.6 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CemA PF03040.14 OEU14066.1 - 0.62 10.0 4.2 1.3 8.9 4.2 1.5 1 0 0 1 1 1 0 CemA family DUF4746 PF15928.5 OEU14066.1 - 0.95 8.8 7.8 1.3 8.3 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 OEU14066.1 - 2.4 6.8 6.3 3.9 6.1 6.3 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_S18 PF01084.20 OEU14067.1 - 0.13 12.5 0.7 5.2 7.4 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S18 Serglycin PF04360.12 OEU14068.1 - 0.004 17.1 3.4 0.0087 16.0 3.4 1.5 1 0 0 1 1 1 1 Serglycin AF-4 PF05110.13 OEU14068.1 - 0.0058 14.8 11.9 0.0088 14.2 11.9 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PAF-AH_p_II PF03403.13 OEU14071.1 - 2.5e-18 65.8 0.0 6.9e-15 54.4 0.0 2.6 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OEU14071.1 - 1.3e-05 24.7 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU14071.1 - 0.00052 19.7 0.0 0.01 15.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OEU14071.1 - 0.0019 17.2 0.0 0.0082 15.1 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 OEU14071.1 - 0.063 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 OEU14071.1 - 0.16 11.8 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family PQQ_2 PF13360.6 OEU14072.1 - 9.6e-06 25.3 0.5 0.0064 16.1 0.1 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OEU14072.1 - 0.0001 22.1 3.9 0.083 12.8 0.1 4.0 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.6 OEU14072.1 - 0.038 14.5 15.5 2 9.0 0.2 6.7 7 0 0 7 7 7 0 PQQ-like domain adh_short PF00106.25 OEU14074.1 - 3.2e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU14074.1 - 3.5e-23 82.4 0.0 4.2e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU14074.1 - 2e-06 27.8 0.1 9.7e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 KR domain DUF1860 PF08949.10 OEU14074.1 - 0.00062 19.6 2.2 0.0011 18.8 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1860) Epimerase PF01370.21 OEU14074.1 - 0.17 11.4 0.0 1.1 8.7 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 OEU14075.1 - 1.3e-15 57.3 0.1 6e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Methyltransf_11 PF08241.12 OEU14075.1 - 6.6e-06 26.7 0.0 2.4e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU14075.1 - 8.5e-05 22.4 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU14075.1 - 0.00057 20.5 0.0 0.0024 18.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ALO PF04030.14 OEU14075.1 - 0.0013 18.6 1.2 0.0049 16.7 0.3 2.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Methyltransf_12 PF08242.12 OEU14075.1 - 0.014 16.2 0.0 0.044 14.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OEU14075.1 - 0.023 14.5 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B_3 PF13483.6 OEU14075.1 - 0.099 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Beta-lactamase superfamily domain KH_5 PF13184.6 OEU14075.1 - 0.14 12.3 0.3 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 NusA-like KH domain Peptidase_M50 PF02163.22 OEU14076.1 - 0.00034 20.0 0.6 0.0038 16.5 0.2 2.0 2 0 0 2 2 2 2 Peptidase family M50 Sporozoite_P67 PF05642.11 OEU14077.1 - 0.47 8.5 5.0 0.09 10.8 1.8 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myc_N PF01056.18 OEU14077.1 - 0.81 9.5 4.9 1.1 9.1 4.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SPACA7 PF15307.6 OEU14077.1 - 0.98 9.7 5.0 11 6.3 0.1 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Peroxin-3 PF04882.12 OEU14078.1 - 1.4e-07 31.0 11.3 1.7e-05 24.1 10.7 2.7 2 1 1 3 3 3 2 Peroxin-3 SARAF PF06682.12 OEU14078.1 - 6.1e-05 22.8 4.0 0.00012 21.9 4.0 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Pex2_Pex12 PF04757.14 OEU14078.1 - 0.68 9.5 6.7 0.38 10.3 2.4 2.8 2 1 0 2 2 2 0 Pex2 / Pex12 amino terminal region Ctr PF04145.15 OEU14078.1 - 0.87 10.2 4.8 1.7 9.2 3.7 2.2 2 1 0 2 2 2 0 Ctr copper transporter family Acetyltransf_2 PF00797.17 OEU14079.1 - 9.1e-15 55.1 0.0 7.2e-09 35.8 0.0 2.4 2 1 0 2 2 2 2 N-acetyltransferase FH2 PF02181.23 OEU14079.1 - 0.00018 20.7 3.6 0.00026 20.3 3.6 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Transglut_core PF01841.19 OEU14079.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Tropomyosin_1 PF12718.7 OEU14079.1 - 0.1 12.7 20.8 0.19 11.9 20.8 1.4 1 0 0 1 1 1 0 Tropomyosin like Golgin_A5 PF09787.9 OEU14079.1 - 0.13 11.7 19.9 0.21 11.0 19.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 ERM PF00769.19 OEU14079.1 - 1.2 8.9 22.6 2.8 7.7 22.6 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF641 PF04859.12 OEU14079.1 - 1.5 9.2 9.5 1.1 9.6 7.5 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Cortex-I_coil PF09304.10 OEU14079.1 - 1.6 8.9 15.6 3.4 7.9 15.2 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil LMBR1 PF04791.16 OEU14079.1 - 2.5 6.9 5.4 3.2 6.6 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Laminin_II PF06009.12 OEU14079.1 - 2.6 8.1 9.5 2.3 8.2 7.8 1.7 1 1 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 OEU14079.1 - 2.8 7.2 11.3 4.4 6.6 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 OEU14079.1 - 4.7 6.5 10.2 7.1 5.9 10.2 1.2 1 0 0 1 1 1 0 FAM76 protein YabA PF06156.13 OEU14079.1 - 4.9 7.8 17.4 16 6.2 4.5 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 OEU14079.1 - 7.3 6.1 11.5 11 5.5 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 OEU14079.1 - 7.9 6.5 9.6 3.8 7.6 4.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) MFS_5 PF05631.14 OEU14081.1 - 6.7e-13 48.3 0.7 2.7e-05 23.3 0.0 2.8 2 1 0 2 2 2 2 Sugar-tranasporters, 12 TM CENP-B_dimeris PF09026.10 OEU14081.1 - 0.079 13.3 7.7 2.9 8.3 2.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TPR_9 PF13371.6 OEU14082.1 - 2.6e-09 37.1 0.3 5.5e-06 26.4 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU14082.1 - 1.6e-08 34.0 1.5 8e-06 25.5 0.2 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU14082.1 - 6.7e-07 29.0 7.6 0.0002 21.2 0.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU14082.1 - 7.6e-06 25.5 0.7 0.0014 18.3 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 OEU14082.1 - 4.4e-05 24.0 6.0 0.00037 21.1 1.5 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU14082.1 - 8.4e-05 23.1 1.4 0.28 12.1 0.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU14082.1 - 0.00011 22.3 1.9 0.61 10.6 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU14082.1 - 0.00019 21.9 2.3 0.00059 20.3 2.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU14082.1 - 0.00023 21.1 2.2 0.51 10.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat GRP PF07172.11 OEU14082.1 - 0.0053 17.4 10.3 0.01 16.5 10.3 1.4 1 0 0 1 1 1 1 Glycine rich protein family TPR_12 PF13424.6 OEU14082.1 - 0.0061 16.8 1.9 0.086 13.1 1.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 OEU14082.1 - 0.034 13.4 0.3 0.034 13.4 0.3 1.4 2 0 0 2 2 2 0 Tetratricopeptide repeat STI1 PF17830.1 OEU14082.1 - 0.038 13.9 1.8 0.33 10.9 0.2 2.9 3 0 0 3 3 3 0 STI1 domain Microvir_H PF04687.12 OEU14082.1 - 0.07 12.5 0.5 0.075 12.4 0.5 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) TPR_7 PF13176.6 OEU14082.1 - 0.12 12.5 0.7 4.7 7.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 OEU14082.1 - 0.23 11.2 4.5 0.31 10.8 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2514 PF10721.9 OEU14082.1 - 0.33 11.0 6.5 0.77 9.8 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Borrelia_P83 PF05262.11 OEU14082.1 - 0.62 8.5 7.0 0.71 8.3 7.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MIT PF04212.18 OEU14082.1 - 0.68 10.0 12.9 0.34 11.0 0.4 3.7 3 1 0 3 3 2 0 MIT (microtubule interacting and transport) domain Forkhead_N PF08430.12 OEU14082.1 - 1.2 9.7 14.2 2 9.0 14.2 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region DUF1682 PF07946.14 OEU14082.1 - 1.8 7.7 12.7 2.5 7.2 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Nitroreductase PF00881.24 OEU14083.1 - 2.2e-17 63.6 0.0 1.6e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Nitroreductase family EF-hand_1 PF00036.32 OEU14083.1 - 8.9e-13 46.8 0.3 1.8e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OEU14083.1 - 1.1e-12 48.2 0.1 5.6e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU14083.1 - 8.6e-12 44.0 0.1 1.5e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU14083.1 - 1e-10 40.6 0.1 0.0008 19.2 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OEU14083.1 - 1.4e-08 34.4 1.1 4.3e-05 23.3 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OEU14083.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU14083.1 - 0.019 15.2 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region CNOT1_TTP_bind PF16417.5 OEU14083.1 - 0.025 13.8 0.2 0.04 13.1 0.2 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Dockerin_1 PF00404.18 OEU14083.1 - 0.043 14.0 0.0 0.2 11.9 0.1 2.2 2 1 0 2 2 2 0 Dockerin type I domain KH_1 PF00013.29 OEU14084.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 KH domain DUF2062 PF09835.9 OEU14085.1 - 0.064 13.1 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) TraL PF07178.11 OEU14085.1 - 0.098 13.1 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 TraL protein DNA_pol_B_N PF18094.1 OEU14085.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase beta N-terminal domain RIFIN PF02009.16 OEU14085.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Rifin DUF952 PF06108.12 OEU14086.1 - 3.3e-08 33.4 0.0 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF952) EutQ PF06249.12 OEU14086.1 - 0.037 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DLIC PF05783.11 OEU14086.1 - 0.053 12.3 0.1 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MtrG PF04210.13 OEU14086.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Acetyltransf_1 PF00583.25 OEU14087.1 - 2.7e-07 30.8 0.0 1.7e-06 28.2 0.0 2.3 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU14087.1 - 2.2e-06 28.0 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU14087.1 - 0.00017 21.7 0.0 0.71 10.0 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU14087.1 - 0.0048 16.8 0.0 0.024 14.6 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 OEU14087.1 - 0.0075 16.2 0.0 0.069 13.1 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DNA_pol_phi PF04931.13 OEU14087.1 - 1.5 6.8 6.9 1.9 6.5 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lipase_GDSL_2 PF13472.6 OEU14088.1 - 1.5e-24 87.4 0.2 2.6e-24 86.6 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU14088.1 - 1.6e-21 77.2 0.0 2.1e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NolV PF06635.12 OEU14088.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolV Me-amine-dh_H PF06433.11 OEU14089.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) TFIIA PF03153.13 OEU14090.1 - 0.98 9.3 12.6 1.3 9.0 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-4B PF06273.11 OEU14093.1 - 0.26 10.3 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF2181 PF10223.9 OEU14094.1 - 7.9e-33 113.9 1.5 3.9e-25 88.7 0.1 2.6 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2181) Lipid_DES PF08557.10 OEU14094.1 - 0.045 13.3 0.3 5.3 6.6 0.0 2.6 1 1 1 2 2 2 0 Sphingolipid Delta4-desaturase (DES) GH-E PF14410.6 OEU14094.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues ALMT PF11744.8 OEU14095.1 - 4.9e-16 58.6 0.0 7.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC PF04632.12 OEU14095.1 - 1.9e-10 40.0 0.5 2e-09 36.6 0.5 2.1 1 1 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 OEU14095.1 - 9.5e-10 38.7 7.1 4.4e-09 36.5 7.1 2.0 1 1 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 OEU14095.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Phosphonate-bd PF12974.7 OEU14098.1 - 2e-10 40.7 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Dynein_heavy PF03028.15 OEU14098.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain PLA2_B PF01735.18 OEU14099.1 - 0.29 9.5 2.5 0.19 10.1 0.9 1.4 2 0 0 2 2 2 0 Lysophospholipase catalytic domain HA PF03457.14 OEU14100.1 - 3e-38 130.0 13.0 4.9e-20 71.6 1.4 2.7 3 0 0 3 3 3 2 Helicase associated domain Phage_DsbA PF11126.8 OEU14100.1 - 0.047 13.9 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator DsbA DUF3926 PF13080.6 OEU14101.1 - 0.0012 18.7 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3926) PDZ_6 PF17820.1 OEU14102.1 - 2e-06 27.5 0.5 0.073 12.9 0.2 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OEU14102.1 - 7.7e-05 22.9 0.0 0.068 13.5 0.0 3.7 4 0 0 4 4 4 1 PDZ domain PDZ PF00595.24 OEU14102.1 - 0.00019 21.7 0.0 0.09 13.1 0.0 2.8 2 0 0 2 2 2 2 PDZ domain DUF3394 PF11874.8 OEU14102.1 - 0.61 9.7 0.0 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) CDH1_2_SANT_HL1 PF18375.1 OEU14102.1 - 1.6 9.4 4.6 10 6.9 1.8 3.2 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 PI3_PI4_kinase PF00454.27 OEU14103.1 - 1.2e-32 113.7 0.1 4.3e-31 108.6 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TFIIS_C PF01096.18 OEU14104.1 - 1.4e-14 53.6 0.6 1.4e-14 53.6 0.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 OEU14104.1 - 0.00029 20.8 4.7 0.089 12.8 0.4 2.6 2 1 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.16 OEU14104.1 - 0.029 14.2 0.8 0.029 14.2 0.8 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit RPA_interact_C PF14768.6 OEU14104.1 - 0.067 13.8 1.6 0.12 13.0 1.6 1.4 1 1 0 1 1 1 0 Replication protein A interacting C-terminal UPF0547 PF10571.9 OEU14104.1 - 0.24 11.5 8.3 2 8.6 0.7 3.4 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 OEU14104.1 - 0.55 10.3 4.7 0.75 9.8 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-TFIIB PF13453.6 OEU14104.1 - 0.82 9.1 10.6 0.29 10.5 1.8 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-CSL PF05207.13 OEU14104.1 - 0.86 9.4 4.6 0.31 10.8 0.3 2.1 2 0 0 2 2 2 0 CSL zinc finger Zn_Tnp_IS91 PF14319.6 OEU14104.1 - 1 9.4 4.9 1.5 8.9 0.4 2.7 2 1 0 2 2 2 0 Transposase zinc-binding domain TF_Zn_Ribbon PF08271.12 OEU14104.1 - 4.1 7.0 8.7 2.4 7.7 1.1 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 OEU14104.1 - 5.2 7.1 11.3 9.2 6.3 0.1 3.9 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 OEU14104.1 - 6.2 6.7 10.2 0.19 11.5 1.2 2.8 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 OEU14104.1 - 8.1 6.5 6.3 30 4.7 0.7 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sas10_Utp3 PF04000.15 OEU14105.1 - 3.3e-06 27.6 0.6 3.3e-06 27.6 0.6 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family PALP PF00291.25 OEU14106.1 - 4.2e-29 101.9 0.0 5.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 OEU14107.1 - 1.8e-87 290.5 0.0 3.1e-43 147.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU14107.1 - 4.2e-24 84.1 0.1 7.8e-11 41.6 0.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OEU14107.1 - 1.3e-12 47.7 0.0 2.2e-05 24.2 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OEU14107.1 - 3e-12 47.3 5.0 0.00032 21.1 0.4 4.6 4 1 0 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 OEU14107.1 - 1.5e-10 41.4 0.0 0.00012 22.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OEU14107.1 - 2.7e-10 40.6 0.0 0.00014 22.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OEU14107.1 - 3.2e-08 33.7 0.5 0.0098 15.9 0.2 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OEU14107.1 - 4.8e-08 33.6 1.2 0.012 16.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OEU14107.1 - 6.7e-08 32.9 0.9 0.0047 17.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU14107.1 - 1e-07 32.3 0.0 0.0056 17.1 0.0 3.0 3 0 0 3 3 2 2 RNA helicase TIP49 PF06068.13 OEU14107.1 - 1.5e-07 31.0 0.1 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 OEU14107.1 - 6e-07 29.6 0.0 0.0081 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OEU14107.1 - 8.9e-07 28.8 0.2 0.076 12.7 0.0 3.0 2 1 1 3 3 3 2 IstB-like ATP binding protein TsaE PF02367.17 OEU14107.1 - 1.4e-06 28.3 0.0 0.036 14.1 0.0 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OEU14107.1 - 2.2e-06 28.1 0.0 0.08 13.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OEU14107.1 - 2.7e-06 27.4 0.1 0.64 9.9 0.0 3.7 3 0 0 3 3 3 2 NACHT domain Mg_chelatase PF01078.21 OEU14107.1 - 3.7e-06 26.5 3.9 0.03 13.7 0.1 3.1 4 0 0 4 4 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 OEU14107.1 - 3.9e-06 26.8 0.3 0.00012 22.0 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 OEU14107.1 - 6.4e-06 25.6 0.0 0.0039 16.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 OEU14107.1 - 9.3e-06 26.0 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OEU14107.1 - 1.8e-05 24.4 0.0 0.082 12.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 OEU14107.1 - 3.5e-05 23.3 0.1 0.27 10.5 0.1 2.9 2 1 0 2 2 2 2 KaiC Parvo_NS1 PF01057.17 OEU14107.1 - 4.6e-05 22.6 0.2 0.081 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 OEU14107.1 - 8.8e-05 22.3 0.2 0.84 9.3 0.1 3.5 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 OEU14107.1 - 0.00011 22.7 0.2 0.74 10.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter Rad17 PF03215.15 OEU14107.1 - 0.00018 21.5 0.0 0.098 12.6 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 OEU14107.1 - 0.0002 21.4 0.1 1.9 8.3 0.0 3.5 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OEU14107.1 - 0.00025 20.7 0.2 2.1 7.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OEU14107.1 - 0.00044 20.0 0.0 0.98 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OEU14107.1 - 0.00047 19.5 0.1 0.1 11.8 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 OEU14107.1 - 0.0005 20.2 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OEU14107.1 - 0.00057 19.7 0.0 0.54 9.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OEU14107.1 - 0.0013 18.0 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.6 OEU14107.1 - 0.0018 18.1 1.0 1.7 8.3 0.0 3.1 4 0 0 4 4 3 1 AAA domain Hydin_ADK PF17213.3 OEU14107.1 - 0.0019 18.5 1.8 0.25 11.6 0.0 3.1 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain Bac_DnaA PF00308.18 OEU14107.1 - 0.0019 18.1 0.4 0.46 10.3 0.2 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_3 PF07726.11 OEU14107.1 - 0.0024 17.7 0.0 1.3 8.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OEU14107.1 - 0.0037 16.4 0.0 0.22 10.5 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 OEU14107.1 - 0.0064 16.2 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OEU14107.1 - 0.0071 16.7 1.2 2.4 8.5 0.1 3.1 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 OEU14107.1 - 0.0077 15.7 0.4 2.3 7.6 0.0 2.7 2 1 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 OEU14107.1 - 0.016 15.2 0.2 4.8 7.2 0.0 2.9 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit IPT PF01745.16 OEU14107.1 - 0.02 14.3 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_6 PF12774.7 OEU14107.1 - 0.028 13.4 0.1 10 4.9 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 OEU14107.1 - 0.036 13.8 0.0 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.6 OEU14107.1 - 0.073 13.2 0.0 6.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family SRPRB PF09439.10 OEU14107.1 - 0.083 12.3 0.0 5.4 6.4 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 OEU14107.1 - 0.093 13.2 1.4 13 6.3 0.0 3.1 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 OEU14107.1 - 0.1 12.5 0.0 25 4.7 0.0 2.8 2 0 0 2 2 2 0 NTPase Polyoma_lg_T_C PF06431.11 OEU14107.1 - 0.14 11.0 0.0 16 4.2 0.0 2.4 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus TniB PF05621.11 OEU14107.1 - 0.15 11.4 0.0 15 4.9 0.0 3.0 4 0 0 4 4 3 0 Bacterial TniB protein KTI12 PF08433.10 OEU14107.1 - 0.16 11.4 0.1 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NOA36 PF06524.12 OEU14107.1 - 9.7 5.4 8.0 14 4.8 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein Mannosyl_trans PF05007.13 OEU14108.1 - 9.4e-55 186.3 16.1 1.4e-54 185.7 16.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 OEU14108.1 - 4.1e-16 59.0 6.7 4.1e-16 59.0 6.7 1.8 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U TACC_C PF05010.14 OEU14109.1 - 0.0072 16.1 21.6 0.0072 16.1 21.6 2.5 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Lebercilin PF15619.6 OEU14109.1 - 0.21 11.2 41.1 0.74 9.4 11.9 3.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 OEU14109.1 - 0.37 9.6 35.1 0.43 9.4 35.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 OEU14109.1 - 2.8 8.1 22.0 0.87 9.8 11.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 OEU14109.1 - 3.7 8.1 24.1 0.17 12.4 10.7 3.2 1 1 1 3 3 3 0 Spectrin repeat Hamartin PF04388.12 OEU14109.1 - 7.6 5.1 28.9 9 4.8 28.9 1.0 1 0 0 1 1 1 0 Hamartin protein TarH PF02203.15 OEU14109.1 - 8.3 6.3 17.4 0.11 12.4 2.5 2.6 1 1 1 2 2 2 0 Tar ligand binding domain homologue Macoilin PF09726.9 OEU14109.1 - 8.3 4.8 32.9 10 4.5 32.9 1.1 1 0 0 1 1 1 0 Macoilin family Tweety PF04906.13 OEU14109.1 - 9.6 4.7 6.3 1.3 7.6 2.3 1.6 2 0 0 2 2 2 0 Tweety LCAT PF02450.15 OEU14110.1 - 3.3e-44 151.6 0.3 2.5e-26 92.7 0.1 2.6 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 OEU14110.1 - 0.02 14.4 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DDHD PF02862.17 OEU14110.1 - 0.02 15.1 0.3 0.032 14.4 0.3 1.3 1 0 0 1 1 1 0 DDHD domain FAM91_C PF14648.6 OEU14110.1 - 0.028 13.3 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 FAM91 C-terminus PIEZO PF15917.5 OEU14110.1 - 0.038 13.5 8.4 0.083 12.4 8.4 1.5 1 0 0 1 1 1 0 Piezo UPF0524 PF15823.5 OEU14110.1 - 0.085 12.2 1.2 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 FAM60A PF15396.6 OEU14110.1 - 0.098 12.6 4.8 0.18 11.8 4.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4834 PF16118.5 OEU14110.1 - 0.15 13.0 5.1 0.41 11.6 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ctr PF04145.15 OEU14110.1 - 0.39 11.3 1.1 0.82 10.3 1.1 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Connexin PF00029.19 OEU14110.1 - 0.45 10.2 2.7 0.8 9.4 2.7 1.4 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 OEU14110.1 - 0.45 9.2 4.7 0.68 8.6 4.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 OEU14110.1 - 0.48 9.7 3.9 0.76 9.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydin_ADK PF17213.3 OEU14110.1 - 0.64 10.3 3.5 1.1 9.5 3.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF1168 PF06658.12 OEU14110.1 - 0.68 9.8 14.3 1.5 8.6 14.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) EMC3_TMCO1 PF01956.16 OEU14110.1 - 0.86 9.3 5.6 1.5 8.5 5.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FYDLN_acid PF09538.10 OEU14110.1 - 0.94 10.2 8.7 3.4 8.4 8.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CNDH2_M PF16869.5 OEU14110.1 - 1.4 9.6 18.6 7.4 7.3 13.0 2.9 4 0 0 4 4 2 0 PF16858 MFAP1 PF06991.11 OEU14110.1 - 1.4 8.7 15.0 0.9 9.3 12.7 1.7 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Androgen_recep PF02166.16 OEU14110.1 - 3.1 6.6 11.0 4.5 6.0 11.0 1.1 1 0 0 1 1 1 0 Androgen receptor DUF3464 PF11947.8 OEU14110.1 - 5.4 6.7 7.7 11 5.8 7.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Cwf_Cwc_15 PF04889.12 OEU14110.1 - 7 6.3 20.4 0.072 12.8 12.5 1.6 2 0 0 2 2 1 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 OEU14110.1 - 10 4.8 11.1 19 3.9 11.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IF4E PF01652.18 OEU14111.1 - 5e-33 114.1 0.4 6.6e-33 113.8 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RRM_1 PF00076.22 OEU14112.1 - 5e-08 32.7 0.0 1.8e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.6 OEU14112.1 - 0.011 15.5 2.7 0.057 13.3 2.7 2.1 1 1 0 1 1 1 0 Zinc knuckle Nop52 PF05997.12 OEU14114.1 - 1.7e-15 57.4 0.1 2.9e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF4867 PF16161.5 OEU14114.1 - 0.12 11.8 0.3 0.23 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4867) Tox-SHH PF15652.6 OEU14114.1 - 0.74 10.8 4.9 0.95 10.5 2.5 2.0 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature Galactosyl_T PF01762.21 OEU14115.1 - 2e-12 47.4 4.4 2.9e-11 43.6 0.1 2.2 2 0 0 2 2 2 2 Galactosyltransferase DUF4366 PF14283.6 OEU14116.1 - 0.039 14.0 0.2 0.59 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Arylesterase PF01731.20 OEU14116.1 - 0.2 11.9 1.3 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Arylesterase PQQ_3 PF13570.6 OEU14116.1 - 0.63 10.6 3.9 0.73 10.4 0.8 2.9 2 0 0 2 2 2 0 PQQ-like domain Orf78 PF06024.12 OEU14116.1 - 3.1 8.1 0.0 3.1 8.1 0.0 4.4 5 0 0 5 5 5 0 Orf78 (ac78) LmjF365940-deam PF14421.6 OEU14117.1 - 3.2e-53 180.2 0.1 7.5e-53 179.0 0.1 1.6 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases SLATT_4 PF18186.1 OEU14118.1 - 6.5e-07 29.1 0.6 1.8e-06 27.7 0.6 1.7 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 LMWPc PF01451.21 OEU14118.1 - 0.077 13.4 0.3 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase SLATT_5 PF18160.1 OEU14118.1 - 2.2 7.6 5.2 0.17 11.2 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TC1 PF15063.6 OEU14119.1 - 0.09 12.7 0.1 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Thyroid cancer protein 1 SPT_ssu-like PF11779.8 OEU14119.1 - 0.24 11.1 0.7 0.45 10.2 0.7 1.4 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like MMR_HSR1 PF01926.23 OEU14120.1 - 7.3e-22 77.6 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 OEU14120.1 - 1.1e-21 77.0 24.1 1.9e-12 47.1 8.0 3.9 2 1 1 3 3 3 2 GTP1/OBG ATP_bind_1 PF03029.17 OEU14120.1 - 3.2e-07 30.4 0.1 1.4e-05 25.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OEU14120.1 - 9.1e-07 28.5 0.2 1.3e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OEU14120.1 - 5.7e-05 22.7 0.1 0.0019 17.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OEU14120.1 - 0.00067 18.7 0.2 0.41 9.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OEU14120.1 - 0.0015 18.6 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 2 Dynamin family Arf PF00025.21 OEU14120.1 - 0.0021 17.5 0.2 0.36 10.3 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family ATP-grasp_4 PF13535.6 OEU14121.1 - 1.8e-08 34.1 0.0 1.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 OEU14121.1 - 6.8e-07 29.5 0.2 4e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 OEU14121.1 - 0.00016 21.6 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 OEU14121.1 - 0.001 18.8 0.0 0.039 13.7 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon TTL PF03133.15 OEU14121.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family RimK PF08443.11 OEU14121.1 - 0.1 12.2 0.1 0.38 10.3 0.1 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain UL42 PF17638.2 OEU14122.1 - 0.017 15.1 4.0 0.051 13.5 4.0 1.8 1 0 0 1 1 1 0 HCMV UL42 RSRP PF17069.5 OEU14124.1 - 0.007 16.0 9.5 0.0091 15.6 9.5 1.1 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 Transformer PF06495.11 OEU14124.1 - 0.32 11.1 8.6 0.47 10.5 8.6 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Ndc1_Nup PF09531.10 OEU14124.1 - 0.98 8.0 3.5 1 8.0 3.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 OEU14124.1 - 0.98 8.1 5.8 1.1 8.0 5.8 1.1 1 0 0 1 1 1 0 Presenilin YjbH PF06082.11 OEU14124.1 - 2.2 7.0 8.4 6.7 5.4 7.4 1.8 1 1 1 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Acyltransferase PF01553.21 OEU14125.1 - 8.8e-10 38.3 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase HSF_DNA-bind PF00447.17 OEU14126.1 - 5.2e-22 78.3 0.1 1.3e-21 77.0 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1257 PF06868.11 OEU14127.1 - 7.4e-29 100.1 0.8 9.6e-29 99.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1257) DUF5491 PF17595.2 OEU14127.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5491) DNA_primase_S PF01896.19 OEU14129.1 - 1.2e-51 175.2 0.1 2e-51 174.6 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit Chloroa_b-bind PF00504.21 OEU14130.1 - 5.6e-38 131.0 0.8 7.4e-38 130.6 0.8 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Abhydrolase_6 PF12697.7 OEU14131.1 - 0.00016 22.3 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OEU14131.1 - 0.00037 20.3 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 OEU14131.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OEU14131.1 - 0.0054 16.0 0.0 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU14131.1 - 0.0056 16.4 0.0 0.055 13.1 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 OEU14131.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PI3_PI4_kinase PF00454.27 OEU14132.1 - 4.4e-44 151.2 0.0 6.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OEU14132.1 - 2.1e-08 33.9 1.0 5.2e-08 32.6 0.3 2.0 2 0 0 2 2 2 1 FATC domain DUF4135 PF13575.6 OEU14132.1 - 0.059 12.7 0.0 0.29 10.4 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4135) Plant_tran PF04827.14 OEU14133.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 2 0 0 2 2 2 0 Plant transposon protein Mt_ATP-synt_D PF05873.12 OEU14134.1 - 2.1e-07 30.9 6.5 2.5e-07 30.6 6.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GYF_2 PF14237.6 OEU14134.1 - 0.0011 18.8 0.1 0.15 11.9 0.0 3.0 2 1 1 3 3 3 2 GYF domain 2 3HCDH_N PF02737.18 OEU14135.1 - 4.6e-57 192.8 0.0 6e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OEU14135.1 - 1.8e-28 99.0 0.0 6.1e-28 97.3 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OEU14135.1 - 0.06 13.5 0.2 0.14 12.3 0.2 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase YadA_head PF05658.14 OEU14135.1 - 1.3 9.5 6.8 0.12 12.7 1.1 2.1 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin Glycos_transf_1 PF00534.20 OEU14136.1 - 6.1e-28 97.5 0.0 9.7e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU14136.1 - 7.2e-24 84.7 0.0 1.1e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OEU14136.1 - 4e-12 46.5 0.5 1.4e-11 44.7 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OEU14136.1 - 3.4e-08 34.1 0.0 6.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OEU14136.1 - 2e-06 28.1 0.0 4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 OEU14136.1 - 0.021 14.6 0.3 0.037 13.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CDC48_2 PF02933.17 OEU14136.1 - 0.077 12.8 0.2 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Yae1_N PF09811.9 OEU14137.1 - 0.017 14.8 44.3 23 4.8 5.5 12.0 4 2 6 10 10 10 0 Essential protein Yae1, N terminal KRTAP7 PF15034.6 OEU14137.1 - 0.46 11.5 2.0 52 4.9 0.0 3.5 3 1 1 4 4 4 0 KRTAP type 7 family Pox_Ag35 PF03286.14 OEU14138.1 - 0.02 14.7 3.2 0.033 14.0 3.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ABM PF03992.16 OEU14139.1 - 1.9e-20 72.8 0.0 1.2e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SOR PF07682.11 OEU14139.1 - 0.23 10.3 0.0 0.49 9.2 0.0 1.5 1 1 0 1 1 1 0 Sulphur oxygenase reductase Chloroa_b-bind PF00504.21 OEU14140.1 - 5.1e-32 111.6 0.0 6.6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein FeThRed_B PF02943.15 OEU14141.1 - 1.9e-34 117.8 1.7 2.9e-34 117.3 1.7 1.2 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain peroxidase PF00141.23 OEU14142.1 - 9.7e-12 45.1 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 OEU14143.1 - 5.7e-20 72.0 0.0 7.2e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Thioredoxin PF00085.20 OEU14144.1 - 2.2e-23 82.2 0.0 2.4e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU14144.1 - 5.1e-09 36.5 0.3 1e-07 32.3 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OEU14144.1 - 1.4e-08 34.5 0.1 1.6e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 OEU14144.1 - 3.6e-08 33.2 0.0 4.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU14144.1 - 1.8e-05 25.0 0.2 0.00098 19.4 0.0 2.5 2 1 1 3 3 2 1 Thioredoxin-like Glutaredoxin PF00462.24 OEU14144.1 - 6.5e-05 23.1 0.0 0.00025 21.2 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 OEU14144.1 - 0.00024 21.1 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 OEU14144.1 - 0.00087 19.1 0.2 0.73 9.6 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.6 OEU14144.1 - 0.0018 18.1 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OEU14144.1 - 0.003 17.7 0.0 0.0077 16.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like DUF1947 PF09183.10 OEU14144.1 - 0.0068 16.7 0.3 0.023 15.0 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1947) Thioredoxin_5 PF13743.6 OEU14144.1 - 0.0074 16.0 0.2 0.02 14.6 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 OEU14144.1 - 0.019 14.9 0.3 0.055 13.4 0.1 1.8 1 1 0 2 2 2 0 AhpC/TSA family DUF836 PF05768.14 OEU14144.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF929 PF06053.11 OEU14144.1 - 0.085 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Orthopox_A47 PF06334.11 OEU14144.1 - 0.095 12.0 0.4 0.33 10.2 0.1 1.8 1 1 0 2 2 2 0 Orthopoxvirus A47 protein Redoxin PF08534.10 OEU14144.1 - 0.13 12.0 0.2 0.14 11.9 0.2 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin PF00085.20 OEU14145.1 - 4.5e-23 81.2 0.0 5.9e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OEU14145.1 - 1.1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OEU14145.1 - 1.3e-09 37.9 0.4 1.6e-09 37.5 0.4 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OEU14145.1 - 1.2e-08 35.3 0.3 2.3e-07 31.2 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU14145.1 - 1.4e-05 25.4 0.3 0.0017 18.6 0.0 3.0 1 1 2 3 3 3 1 Thioredoxin-like Glutaredoxin PF00462.24 OEU14145.1 - 9e-05 22.6 0.0 0.00049 20.3 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin DSBA PF01323.20 OEU14145.1 - 0.002 17.9 0.2 1.3 8.8 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.6 OEU14145.1 - 0.0021 17.9 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OEU14145.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_5 PF13743.6 OEU14145.1 - 0.012 15.3 0.1 0.034 13.8 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin DUF1947 PF09183.10 OEU14145.1 - 0.013 15.7 0.3 0.04 14.2 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1947) AhpC-TSA PF00578.21 OEU14145.1 - 0.02 14.8 0.5 0.074 13.0 0.1 2.1 1 1 1 2 2 2 0 AhpC/TSA family DUF836 PF05768.14 OEU14145.1 - 0.021 15.2 0.1 0.11 12.9 0.0 2.0 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 OEU14146.1 - 6.4e-25 87.1 0.5 8.4e-25 86.7 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU14146.1 - 1.2e-07 31.9 0.1 3.1e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU14146.1 - 2.2e-07 31.3 0.7 8.2e-07 29.5 0.7 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OEU14146.1 - 3e-07 30.1 0.1 3.5e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OEU14146.1 - 1.7e-06 28.0 0.1 2.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 OEU14146.1 - 6.2e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 OEU14146.1 - 2.9e-05 24.0 0.0 3.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OEU14146.1 - 0.0001 22.0 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 Redoxin DIM1 PF02966.16 OEU14146.1 - 0.00031 20.5 0.1 0.00043 20.1 0.1 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 OEU14146.1 - 0.00037 20.4 0.1 0.00047 20.1 0.1 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 OEU14146.1 - 0.0007 19.6 0.1 0.0017 18.3 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU14146.1 - 0.0024 17.6 0.1 0.0034 17.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU14146.1 - 0.0051 17.0 0.2 0.008 16.3 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like DSBA PF01323.20 OEU14146.1 - 0.014 15.2 0.7 0.98 9.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain T4_deiodinase PF00837.17 OEU14146.1 - 0.057 12.7 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase DUF836 PF05768.14 OEU14146.1 - 0.095 13.1 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 OEU14146.1 - 0.11 12.6 0.3 0.25 11.5 0.3 1.5 1 1 1 2 2 2 0 Thioredoxin Thioredoxin PF00085.20 OEU14147.1 - 8e-25 86.8 0.5 1.1e-24 86.4 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU14147.1 - 1.5e-07 31.6 0.1 3.9e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU14147.1 - 2.7e-07 31.0 0.6 9.5e-07 29.2 0.6 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OEU14147.1 - 3.5e-07 29.9 0.1 4.3e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OEU14147.1 - 2.1e-06 27.7 0.1 2.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 OEU14147.1 - 7.1e-06 26.2 0.1 1.3e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 OEU14147.1 - 3.6e-05 23.7 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OEU14147.1 - 0.00012 21.8 0.1 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 Redoxin DIM1 PF02966.16 OEU14147.1 - 0.00038 20.2 0.1 0.00053 19.8 0.1 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 OEU14147.1 - 0.00045 20.1 0.1 0.00062 19.7 0.1 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 OEU14147.1 - 0.0009 19.2 0.1 0.0022 18.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU14147.1 - 0.003 17.3 0.1 0.0042 16.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU14147.1 - 0.0061 16.7 0.2 0.0097 16.1 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like DSBA PF01323.20 OEU14147.1 - 0.018 14.8 0.8 1.1 9.0 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain T4_deiodinase PF00837.17 OEU14147.1 - 0.061 12.6 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase DUF836 PF05768.14 OEU14147.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 OEU14147.1 - 0.14 12.3 0.4 0.3 11.2 0.4 1.5 1 1 1 2 2 2 0 Thioredoxin GCS PF03074.16 OEU14148.1 - 1.5e-154 514.8 0.0 2.1e-154 514.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS PF03074.16 OEU14149.1 - 1.7e-154 514.6 0.0 2.4e-154 514.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Glu_cyclase_2 PF05096.12 OEU14150.1 - 1.7e-72 243.9 4.0 2.5e-72 243.4 4.0 1.2 1 0 0 1 1 1 1 Glutamine cyclotransferase DUF3198 PF11433.8 OEU14150.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) DUF4296 PF14129.6 OEU14150.1 - 0.12 12.9 4.7 5.2 7.8 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) Neur_chan_memb PF02932.16 OEU14150.1 - 0.17 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Phytochelatin PF05023.14 OEU14151.1 - 2.1e-72 242.8 0.0 3.9e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 OEU14151.1 - 0.016 15.8 8.3 2 9.0 0.1 3.2 3 0 0 3 3 3 0 Peptidase_C39 like family Dicty_REP PF05086.12 OEU14151.1 - 0.086 10.8 3.9 0.12 10.3 3.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3664 PF12406.8 OEU14151.1 - 0.1 13.2 1.2 0.2 12.3 1.2 1.4 1 0 0 1 1 1 0 Surface protein DUF3439 PF11921.8 OEU14151.1 - 0.19 11.7 3.3 0.64 10.0 3.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Methyltransf_23 PF13489.6 OEU14152.1 - 9.8e-21 74.3 3.3 1.2e-20 74.0 0.3 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU14152.1 - 2.2e-15 57.1 0.0 4.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU14152.1 - 3.6e-13 50.0 0.0 7.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU14152.1 - 5.5e-13 49.0 0.3 1.2e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU14152.1 - 8.1e-12 45.8 0.2 2.7e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 OEU14152.1 - 3.6e-08 33.3 0.0 6.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 OEU14152.1 - 9.2e-05 21.9 0.0 0.00034 20.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OEU14152.1 - 9.4e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 OEU14152.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU14152.1 - 0.00027 20.5 0.0 0.0009 18.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 OEU14152.1 - 0.0023 17.4 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 OEU14152.1 - 0.02 14.9 0.0 0.02 14.9 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain TPMT PF05724.11 OEU14152.1 - 0.029 14.0 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SUIM_assoc PF16619.5 OEU14152.1 - 0.059 13.4 7.1 0.15 12.1 7.1 1.8 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TadF PF16964.5 OEU14152.1 - 0.074 12.8 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Putative tight adherence pilin protein F CYSTM PF12734.7 OEU14152.1 - 8.8 6.7 8.4 28 5.1 8.4 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Tyrosinase PF00264.20 OEU14153.1 - 2.3e-33 116.4 9.0 2.3e-33 116.4 9.0 2.9 2 1 0 2 2 2 2 Common central domain of tyrosinase DAHP_synth_2 PF01474.16 OEU14154.1 - 1.7e-185 616.7 0.0 1.9e-185 616.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family CytB6-F_Fe-S PF08802.10 OEU14154.1 - 0.03 14.4 0.4 0.059 13.4 0.4 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Tocopherol_cycl PF14249.6 OEU14155.1 - 1.8e-100 336.3 11.2 6.2e-97 324.7 6.5 2.9 2 1 0 2 2 2 2 Tocopherol cyclase Radical_SAM PF04055.21 OEU14156.1 - 1.7e-13 51.3 0.0 3.4e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily YacG PF03884.14 OEU14156.1 - 1.3 8.8 5.0 5.1 6.9 0.2 3.1 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG HATPase_c PF02518.26 OEU14157.1 - 4.2e-24 85.2 0.0 6.1e-23 81.5 0.0 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OEU14157.1 - 2.6e-19 69.4 0.4 1.2e-18 67.3 0.0 2.4 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 OEU14157.1 - 7.5e-14 51.5 0.1 1.5e-06 28.1 0.0 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PMAIP1 PF15150.6 OEU14157.1 - 0.066 13.1 0.1 1 9.3 0.1 2.5 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced PAS_4 PF08448.10 OEU14157.1 - 0.12 12.7 0.0 5.6 7.3 0.0 2.7 3 0 0 3 3 3 0 PAS fold PAS PF00989.25 OEU14157.1 - 0.12 12.4 0.0 7.7 6.6 0.0 3.2 3 0 0 3 3 3 0 PAS fold PAS_9 PF13426.7 OEU14158.1 - 2.5e-08 34.1 0.0 7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OEU14158.1 - 4.4e-08 33.1 0.0 1.6e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OEU14158.1 - 0.0095 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain HLH PF00010.26 OEU14159.1 - 8.1e-10 38.5 2.0 1.7e-09 37.5 2.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 OEU14159.1 - 5.7e-09 36.0 0.0 5.7e-09 36.0 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 OEU14159.1 - 1e-06 28.9 0.0 3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OEU14159.1 - 1.6e-05 24.8 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OEU14159.1 - 0.014 15.6 0.2 0.13 12.5 0.0 2.5 2 0 0 2 2 2 0 PAS fold BChl_A PF02327.17 OEU14159.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll A protein SKN1 PF03935.15 OEU14161.1 - 1.3e-72 244.9 9.8 2.3e-61 207.7 9.6 3.8 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) TMEM51 PF15345.6 OEU14161.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_26 PF13500.6 OEU14162.1 - 1.4e-38 132.7 0.0 2.2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OEU14162.1 - 4.7e-08 33.1 0.0 1.3e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Codanin-1_C PF15296.6 OEU14162.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Codanin-1 C-terminus VbhA PF18495.1 OEU14162.1 - 0.13 12.1 1.0 6.4 6.7 0.2 2.7 2 0 0 2 2 2 0 Antitoxin VbhA DUF4147 PF13660.6 OEU14163.1 - 2.7e-74 249.5 0.1 7.5e-74 248.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 OEU14163.1 - 1.9e-32 111.7 2.8 2.4e-32 111.4 1.4 1.9 2 0 0 2 2 2 1 MOFRL family ROK PF00480.20 OEU14164.1 - 6.2e-29 101.4 0.9 3.1e-28 99.1 0.1 2.2 2 1 0 2 2 2 1 ROK family Glucokinase PF02685.16 OEU14164.1 - 0.014 14.4 0.4 0.041 12.9 0.4 1.9 1 1 0 1 1 1 0 Glucokinase GalKase_gal_bdg PF10509.9 OEU14165.1 - 1.1e-17 63.3 0.1 2.7e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 OEU14165.1 - 8.3e-14 51.7 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OEU14165.1 - 7.6e-09 35.7 0.2 2.1e-08 34.3 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain FBPase PF00316.20 OEU14166.1 - 7.5e-52 175.6 0.2 1.2e-51 174.9 0.2 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Alg14 PF08660.11 OEU14167.1 - 1.8e-57 194.1 0.0 3.4e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Atthog PF18800.1 OEU14167.1 - 0.0064 16.4 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 Attenuator of Hedgehog DUF2561 PF10812.8 OEU14167.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Peptidase_M11 PF05548.11 OEU14169.1 - 3.2e-16 59.4 0.0 6.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M10 PF00413.24 OEU14169.1 - 0.0052 16.6 0.1 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 OEU14169.1 - 0.0062 15.5 0.5 0.018 14.0 0.5 1.8 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 OEU14169.1 - 0.0065 17.0 2.3 0.022 15.3 0.4 2.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OEU14169.1 - 0.018 14.7 0.1 0.018 14.7 0.1 2.4 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OEU14169.1 - 0.11 12.6 3.8 0.16 12.1 0.9 2.8 2 1 0 2 2 2 0 Metallo-peptidase family M12 PIP49_C PF12260.8 OEU14169.1 - 0.13 11.9 2.8 0.25 10.9 2.8 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF45 PF01863.17 OEU14169.1 - 4.6 7.2 6.7 10 6.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 YvrJ PF12841.7 OEU14170.1 - 0.06 12.9 0.3 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 YvrJ protein family NAD_binding_8 PF13450.6 OEU14172.1 - 6.1e-07 29.6 0.4 1.4e-06 28.4 0.4 1.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU14172.1 - 3.9e-06 26.3 0.2 5.9e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OEU14172.1 - 2.6e-05 23.5 1.8 3.3e-05 23.2 1.8 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OEU14172.1 - 0.00019 20.9 0.3 0.00025 20.5 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OEU14172.1 - 0.00052 18.8 0.1 0.002 16.9 0.6 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OEU14172.1 - 0.0029 16.9 0.1 0.0035 16.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU14172.1 - 0.03 13.6 0.3 0.041 13.1 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OEU14172.1 - 0.044 13.3 0.4 0.06 12.9 0.4 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 OEU14172.1 - 0.048 12.7 0.5 0.062 12.4 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OEU14172.1 - 0.23 10.7 1.0 0.32 10.2 1.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Baculo_VP1054 PF05789.11 OEU14174.1 - 0.027 13.7 0.4 0.049 12.8 0.1 1.6 2 0 0 2 2 2 0 Baculovirus VP1054 protein IMUP PF15761.5 OEU14174.1 - 4.4 8.0 15.8 12 6.6 3.4 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF563 PF04577.14 OEU14176.1 - 4.7e-05 23.6 0.1 0.00016 21.9 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Abhydrolase_1 PF00561.20 OEU14177.1 - 3.4e-11 43.3 0.0 5.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OEU14177.1 - 1.9e-05 24.7 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OEU14177.1 - 0.24 10.6 0.1 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 FAM176 PF14851.6 OEU14178.1 - 0.32 10.6 1.2 0.44 10.2 1.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 OEU14178.1 - 0.61 11.1 2.3 0.86 10.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 OEU14178.1 - 0.66 10.3 1.8 0.91 9.9 1.8 1.2 1 0 0 1 1 1 0 Orf78 (ac78) CDC45 PF02724.14 OEU14178.1 - 9.2 4.4 6.2 11 4.2 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Hydrolase_3 PF08282.12 OEU14179.1 - 0.0069 16.2 1.6 0.013 15.3 1.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro_67C PF07477.12 OEU14179.1 - 0.028 13.9 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus SCP1201-deam PF14428.6 OEU14182.1 - 0.0094 15.8 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 SCP1.201-like deaminase FMO-like PF00743.19 OEU14184.1 - 6.5e-11 41.3 1.9 4.3e-05 22.1 0.1 3.3 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OEU14184.1 - 9.9e-05 21.7 0.3 0.0017 17.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OEU14184.1 - 0.00027 20.3 0.0 0.24 10.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU14184.1 - 0.0016 18.6 0.0 3.6 7.9 0.0 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Chloroa_b-bind PF00504.21 OEU14185.1 - 8.6e-32 110.9 0.0 1.1e-31 110.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein zf-MYND PF01753.18 OEU14189.1 - 1.1e-06 28.6 13.0 2.5e-06 27.4 13.0 1.7 1 0 0 1 1 1 1 MYND finger PT PF04886.12 OEU14190.1 - 0.068 12.7 10.0 0.11 12.1 10.0 1.3 1 0 0 1 1 1 0 PT repeat Peptidase_M11 PF05548.11 OEU14191.1 - 2.5e-08 33.5 0.6 4.8e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 Gametolysin peptidase M11 Reprolysin_3 PF13582.6 OEU14191.1 - 0.0024 18.4 0.1 0.011 16.3 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU14191.1 - 0.0029 17.4 0.4 0.0058 16.5 0.3 1.8 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 OEU14191.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 OEU14191.1 - 0.02 14.8 0.6 0.045 13.7 0.2 1.7 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A PT PF04886.12 OEU14191.1 - 0.021 14.4 22.3 0.18 11.4 22.3 2.3 1 1 0 1 1 1 0 PT repeat Peptidase_M66 PF10462.9 OEU14191.1 - 0.028 13.4 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 0 Peptidase M66 MCR_beta PF02241.18 OEU14191.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Reprolysin_5 PF13688.6 OEU14191.1 - 3.9 7.6 7.4 0.71 10.0 0.3 2.9 3 2 0 3 3 3 0 Metallo-peptidase family M12 TMEM132D_C PF15706.5 OEU14192.1 - 0.098 12.4 0.1 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Hexapep PF00132.24 OEU14194.1 - 7.2e-13 47.7 7.7 1.2e-07 31.1 1.6 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 OEU14194.1 - 2.4e-10 40.7 0.2 4e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 OEU14194.1 - 3e-05 23.7 9.4 0.00054 19.7 2.2 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Apis_Csd PF11671.8 OEU14195.1 - 0.14 12.2 2.9 0.35 10.9 2.9 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein LRR_6 PF13516.6 OEU14196.1 - 0.00072 19.4 3.4 3.1 8.1 0.0 4.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 OEU14196.1 - 0.0042 16.8 0.7 0.76 9.6 0.1 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU14196.1 - 0.09 13.2 10.7 0.7 10.4 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14196.1 - 3.3 8.6 0.0 3.3 8.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Raffinose_syn PF05691.12 OEU14197.1 - 4.7e-92 309.1 0.0 5.9e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 UL42 PF17638.2 OEU14200.1 - 0.31 11.0 1.8 20 5.2 0.4 2.6 2 0 0 2 2 2 0 HCMV UL42 CxC6 PF18721.1 OEU14201.1 - 0.02 15.2 7.6 0.05 13.9 7.6 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases SDA1 PF05285.12 OEU14201.1 - 0.1 12.0 13.3 0.12 11.7 13.3 1.2 1 0 0 1 1 1 0 SDA1 FOXP-CC PF16159.5 OEU14201.1 - 0.29 11.8 5.3 0.8 10.4 2.7 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain IBR PF01485.21 OEU14201.1 - 0.37 11.0 6.2 0.81 10.0 6.2 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CDC45 PF02724.14 OEU14201.1 - 0.41 8.9 8.9 0.45 8.7 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 OEU14201.1 - 0.65 9.1 22.4 0.99 8.5 22.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BSP_II PF05432.11 OEU14201.1 - 1.7 8.3 25.7 2.3 7.8 25.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FSA_C PF10479.9 OEU14201.1 - 2 6.5 13.0 2.7 6.0 13.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus VIR_N PF15912.5 OEU14202.1 - 0.24 11.0 9.1 0.24 11.0 8.0 1.5 1 1 0 1 1 1 0 Virilizer, N-terminal AIDA PF16168.5 OEU14202.1 - 0.36 11.0 2.8 1 9.5 0.5 2.9 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk RIH_assoc PF08454.11 OEU14202.1 - 6.5 6.7 12.6 17 5.3 3.1 3.8 4 0 0 4 4 4 0 RyR and IP3R Homology associated Sec7 PF01369.20 OEU14203.1 - 7.7e-61 205.0 0.1 1.8e-60 203.8 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OEU14203.1 - 3.1e-25 88.9 5.2 3.1e-25 88.9 5.2 2.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OEU14203.1 - 1.1e-21 76.4 4.1 8.6e-21 73.6 0.3 3.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Chloroa_b-bind PF00504.21 OEU14205.1 - 1.2e-42 146.2 0.0 1.7e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ELM2 PF01448.24 OEU14206.1 - 0.16 12.8 0.4 1.8 9.4 0.1 2.6 2 1 0 2 2 2 0 ELM2 domain Cnn_1N PF07989.11 OEU14207.1 - 0.048 13.8 2.8 0.048 13.8 2.8 4.4 4 1 0 4 4 4 0 Centrosomin N-terminal motif 1 7TM_GPCR_Srab PF10292.9 OEU14207.1 - 0.086 11.7 1.6 0.17 10.8 1.6 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF2703 PF10865.8 OEU14207.1 - 0.5 10.6 8.2 1 9.5 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) ATG16 PF08614.11 OEU14208.1 - 0.00087 19.6 47.6 0.049 13.8 6.0 3.7 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) DUF2203 PF09969.9 OEU14208.1 - 0.0029 18.3 2.7 0.0029 18.3 2.7 3.6 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2203) DUF2353 PF09789.9 OEU14208.1 - 0.0049 16.3 38.3 0.0073 15.7 38.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) HOOK PF05622.12 OEU14208.1 - 0.032 12.4 43.4 0.06 11.5 11.8 3.0 1 1 2 3 3 3 0 HOOK protein Ac76 PF05814.11 OEU14208.1 - 0.12 12.4 2.7 0.45 10.5 0.9 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) E2R135 PF11570.8 OEU14208.1 - 0.15 12.3 11.3 1.8 8.9 5.3 3.0 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Phage_GP20 PF06810.11 OEU14208.1 - 0.17 11.7 33.4 0.44 10.3 21.4 3.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 2_5_RNA_ligase2 PF13563.6 OEU14208.1 - 0.22 11.5 2.0 1.1 9.1 0.2 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily DUF1492 PF07374.11 OEU14208.1 - 0.35 11.1 10.6 1.3 9.2 0.8 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1492) HALZ PF02183.18 OEU14208.1 - 0.88 9.8 29.3 1.7 8.9 0.1 6.8 5 2 2 7 7 7 0 Homeobox associated leucine zipper Rootletin PF15035.6 OEU14208.1 - 1 9.4 42.4 0.85 9.6 16.1 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 OEU14208.1 - 1.9 7.8 48.2 4.5 6.6 12.0 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 OEU14208.1 - 3.4 8.1 23.6 9.4 6.7 0.1 6.2 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 OEU14208.1 - 3.4 7.9 38.6 1.2 9.4 10.8 4.1 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain NAD_binding_5 PF07994.12 OEU14208.1 - 3.6 6.9 8.6 0.63 9.4 4.9 1.6 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase FAM176 PF14851.6 OEU14209.1 - 0.38 10.4 11.0 7 6.3 0.3 3.4 3 0 0 3 3 3 0 FAM176 family ABC_membrane PF00664.23 OEU14210.1 - 3.4e-75 253.2 23.9 4.4e-39 134.8 6.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU14210.1 - 5.3e-53 179.2 0.0 7.6e-30 104.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 OEU14210.1 - 1.7e-07 31.6 1.1 0.018 15.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 OEU14210.1 - 1.9e-07 30.8 0.0 5.5e-05 22.7 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU14210.1 - 2.9e-07 31.0 1.4 0.02 15.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU14210.1 - 1.5e-06 27.8 1.7 0.022 14.5 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OEU14210.1 - 4.7e-05 23.4 0.2 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OEU14210.1 - 9.9e-05 22.0 1.7 0.31 10.6 0.1 3.5 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OEU14210.1 - 0.00014 21.8 0.3 0.41 10.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OEU14210.1 - 0.00026 21.5 0.1 0.13 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OEU14210.1 - 0.00044 20.3 0.1 0.12 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OEU14210.1 - 0.00046 20.4 0.1 0.11 12.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OEU14210.1 - 0.0011 19.4 0.4 3.4 8.1 0.2 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OEU14210.1 - 0.0012 18.9 1.1 3.5 7.7 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase MoaE PF02391.17 OEU14210.1 - 0.0015 18.8 0.1 7.6 6.9 0.0 3.4 3 0 0 3 3 3 0 MoaE protein AAA_7 PF12775.7 OEU14210.1 - 0.0017 17.9 0.1 0.94 9.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OEU14210.1 - 0.0046 17.3 0.3 4.4 7.8 0.1 2.8 3 0 0 3 3 2 1 RNA helicase DEAD PF00270.29 OEU14210.1 - 0.0049 16.7 0.3 0.035 13.9 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_23 PF13476.6 OEU14210.1 - 0.005 17.4 0.1 2 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OEU14210.1 - 0.0071 16.1 3.4 2.4 7.8 0.3 2.9 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 OEU14210.1 - 0.019 14.9 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 OEU14210.1 - 0.027 14.6 2.1 3.3 7.8 0.2 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_28 PF13521.6 OEU14210.1 - 0.028 14.7 0.6 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OEU14210.1 - 0.045 13.7 1.1 33 4.3 0.0 3.6 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.6 OEU14210.1 - 0.049 13.3 0.2 2.9 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OEU14210.1 - 0.065 12.4 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 OEU14210.1 - 0.065 13.1 0.2 15 5.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.20 OEU14210.1 - 0.092 12.6 0.3 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase G-alpha PF00503.20 OEU14210.1 - 0.11 11.7 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 OEU14210.1 - 0.13 11.6 0.1 9.8 5.4 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin NST1 PF13945.6 OEU14210.1 - 0.43 10.7 2.5 0.77 9.8 2.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator AAA_10 PF12846.7 OEU14210.1 - 0.44 9.4 3.1 6.1 5.7 0.1 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_15 PF13175.6 OEU14210.1 - 0.83 9.3 4.4 3.6 7.2 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain LRR_8 PF13855.6 OEU14211.1 - 4.1e-39 132.1 53.7 2.2e-09 36.9 4.9 6.2 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OEU14211.1 - 2.2e-22 78.7 43.4 0.0016 18.8 0.7 8.4 3 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14211.1 - 7.7e-17 59.3 22.6 1.6 9.6 0.2 12.9 13 0 0 13 13 13 4 Leucine Rich Repeat LRR_9 PF14580.6 OEU14211.1 - 8.4e-05 22.1 13.0 0.11 12.0 0.1 4.1 2 1 2 5 5 5 3 Leucine-rich repeat Peptidase_C21 PF05381.12 OEU14211.1 - 0.035 14.5 0.9 9.6 6.6 0.1 3.1 3 1 0 3 3 3 0 Tymovirus endopeptidase LRR_6 PF13516.6 OEU14211.1 - 0.059 13.5 30.1 3.9 7.8 0.1 9.5 10 0 0 10 10 10 0 Leucine Rich repeat LRR_5 PF13306.6 OEU14211.1 - 0.068 13.1 0.6 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Ribosomal_60s PF00428.19 OEU14212.1 - 6.1 7.5 8.5 0.25 11.9 0.6 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein LRR_8 PF13855.6 OEU14213.1 - 7.9e-22 76.8 21.8 5.6e-05 22.8 0.1 5.7 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OEU14213.1 - 9.2e-20 70.4 24.8 0.00055 20.3 0.0 8.0 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14213.1 - 6.1e-07 29.1 14.4 5.2 8.0 0.1 9.7 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU14213.1 - 0.011 15.8 13.3 30 5.0 0.9 7.4 8 0 0 8 8 8 0 Leucine Rich repeat Yae1_N PF09811.9 OEU14214.1 - 5.4e-11 42.0 84.7 0.96 9.2 1.0 18.5 5 4 9 15 15 15 10 Essential protein Yae1, N terminal Rick_17kDa_Anti PF05433.15 OEU14214.1 - 0.019 14.8 9.0 0.019 14.8 9.0 11.6 3 3 7 10 10 10 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OEU14214.1 - 7.9 6.6 84.8 0.07 13.1 11.0 9.4 2 2 4 6 6 6 0 Glycine zipper DUF3641 PF12345.8 OEU14216.1 - 2.4e-48 163.6 0.2 4.3e-48 162.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 OEU14216.1 - 3.2e-07 30.9 0.0 5.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OEU14216.1 - 2.8e-06 27.7 0.0 6.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain AFG1_ATPase PF03969.16 OEU14216.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase TPR_MLP1_2 PF07926.12 OEU14217.1 - 0.00065 19.8 5.0 0.0011 19.1 5.0 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Flagellar_rod PF05149.12 OEU14217.1 - 0.0033 17.0 6.2 0.01 15.3 6.2 1.7 1 1 0 1 1 1 1 Paraflagellar rod protein Spc7 PF08317.11 OEU14217.1 - 0.086 11.7 3.5 0.14 11.0 3.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 OEU14217.1 - 0.21 12.2 1.6 0.44 11.2 1.6 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Atg14 PF10186.9 OEU14217.1 - 0.29 10.2 2.8 0.37 9.8 2.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 OEU14217.1 - 0.32 11.1 1.8 6.4 6.9 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CENP-F_leu_zip PF10473.9 OEU14217.1 - 0.32 11.0 10.6 2.1 8.3 2.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PV-1 PF06637.11 OEU14217.1 - 0.86 8.4 8.1 13 4.5 8.5 1.9 1 1 0 1 1 1 0 PV-1 protein (PLVAP) GTP-bdg_M PF16360.5 OEU14217.1 - 1.6 9.3 13.3 7.1 7.3 2.7 2.4 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region APG6_N PF17675.1 OEU14217.1 - 3 8.4 9.2 7.5 7.1 9.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DegS PF05384.11 OEU14217.1 - 3.1 7.3 12.4 0.36 10.3 4.2 2.2 1 1 1 2 2 2 0 Sensor protein DegS DUF2207 PF09972.9 OEU14218.1 - 0.0046 15.8 0.0 0.01 14.6 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Otopetrin PF03189.13 OEU14218.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Otopetrin TIM PF00121.18 OEU14220.1 - 3.9e-81 272.0 0.0 4.5e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Methyltransf_32 PF13679.6 OEU14221.1 - 6.7e-08 32.7 2.7 4.1e-07 30.1 2.7 2.4 1 1 0 1 1 1 1 Methyltransferase domain Arc_PepC_II PF06847.11 OEU14221.1 - 0.47 11.0 2.2 5.4 7.6 0.1 3.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Serinc PF03348.15 OEU14221.1 - 3.5 6.5 6.8 0.21 10.4 1.2 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) APG17 PF04108.12 OEU14222.1 - 0.0057 15.8 4.1 0.0069 15.6 4.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 PRIMA1 PF16101.5 OEU14222.1 - 0.015 15.3 2.0 0.029 14.4 2.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2052 PF09747.9 OEU14222.1 - 0.098 12.8 5.7 0.11 12.6 5.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF966 PF06136.13 OEU14222.1 - 0.22 11.2 10.9 0.26 11.0 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) V_ATPase_I PF01496.19 OEU14222.1 - 0.39 8.6 2.6 0.45 8.4 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF3_N PF09440.10 OEU14222.1 - 0.45 11.0 7.2 0.61 10.5 6.9 1.3 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain ThiD2 PF17792.1 OEU14222.1 - 0.81 10.2 6.2 0.29 11.6 3.6 1.5 1 1 1 2 2 2 0 ThiD2 family Cytochrom_C552 PF02335.15 OEU14222.1 - 0.84 8.5 9.8 1.1 8.2 9.8 1.0 1 0 0 1 1 1 0 Cytochrome c552 Presenilin PF01080.17 OEU14222.1 - 3.2 6.4 8.6 3.9 6.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin RCDG1 PF15725.5 OEU14222.1 - 3.3 8.2 8.2 0.77 10.2 3.2 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Vfa1 PF08432.10 OEU14222.1 - 8.3 6.7 17.4 12 6.2 17.3 1.3 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FKBP_C PF00254.28 OEU14223.1 - 1.8e-11 44.2 0.0 3.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4465 PF14717.6 OEU14223.1 - 0.025 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4465) Lar_N PF09861.9 OEU14224.1 - 3.6e-07 29.6 0.1 0.0023 17.1 0.1 2.8 2 1 0 2 2 2 2 Lactate racemase N-terminal domain DDE_3 PF13358.6 OEU14225.1 - 0.069 12.9 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3606 PF12244.8 OEU14226.1 - 0.078 12.9 0.2 0.89 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) TFIIA PF03153.13 OEU14226.1 - 0.28 11.1 45.4 0.44 10.5 45.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HA PF03457.14 OEU14229.1 - 3.9e-31 107.2 1.3 6.9e-18 64.8 0.2 2.0 2 0 0 2 2 2 2 Helicase associated domain cwf21 PF08312.12 OEU14230.1 - 0.1 12.8 2.2 5.7 7.2 0.2 2.8 2 0 0 2 2 2 0 cwf21 domain Rrp44_CSD1 PF17216.3 OEU14230.1 - 3.8 7.2 7.8 5.2 6.8 6.7 1.8 2 0 0 2 2 2 0 Rrp44-like cold shock domain Sulfotransfer_1 PF00685.27 OEU14231.1 - 2.1e-17 63.5 0.2 3.8e-17 62.6 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU14231.1 - 0.00011 22.7 2.2 0.0049 17.3 0.1 3.1 1 1 1 2 2 2 1 Sulfotransferase family DUF4070 PF13282.6 OEU14231.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) DUF819 PF05684.12 OEU14233.1 - 2.8e-31 108.9 19.7 4e-31 108.4 19.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Cyd_oper_YbgE PF09600.10 OEU14233.1 - 0.39 11.1 5.9 0.2 12.1 0.3 3.3 3 0 0 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF4698 PF15769.5 OEU14233.1 - 8.8 5.3 7.0 13 4.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Dirigent PF03018.14 OEU14234.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Dirigent-like protein Use1 PF09753.9 OEU14236.1 - 2.4e-10 40.6 9.9 2.4e-10 40.6 9.9 4.6 4 1 1 5 5 5 1 Membrane fusion protein Use1 Ank_2 PF12796.7 OEU14236.1 - 8.2e-08 32.7 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU14236.1 - 1.5e-06 28.6 0.1 3.6e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU14236.1 - 5.5e-06 26.5 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU14236.1 - 2.5e-05 24.5 0.1 5.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 OEU14236.1 - 0.00023 21.3 0.0 0.00076 19.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat SNARE PF05739.19 OEU14236.1 - 0.042 13.8 0.7 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 SNARE domain Phage_XkdX PF09693.10 OEU14237.1 - 0.074 13.1 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Thioredoxin_2 PF13098.6 OEU14238.1 - 0.1 13.0 0.1 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain Hemerythrin PF01814.23 OEU14238.1 - 0.11 13.1 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Nop14 PF04147.12 OEU14241.1 - 0.56 8.3 4.2 0.56 8.4 4.2 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OEU14241.1 - 0.86 7.6 10.0 0.91 7.5 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 OEU14241.1 - 0.89 7.3 6.4 1 7.1 6.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 OEU14241.1 - 1 8.6 14.7 0.25 10.6 8.5 2.0 2 0 0 2 2 2 0 NOA36 protein DUF3915 PF13054.6 OEU14241.1 - 3.7 7.6 6.4 7.8 6.5 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) BUD22 PF09073.10 OEU14241.1 - 6.2 6.1 10.1 7.8 5.7 10.1 1.2 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 OEU14242.1 - 1.6e-10 40.8 0.0 1.8e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14242.1 - 4.2e-07 29.5 0.0 0.018 14.4 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Zip PF02535.22 OEU14243.1 - 0.67 9.1 4.5 0.75 8.9 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter 4HBT PF03061.22 OEU14244.1 - 1.6e-07 31.6 0.0 1.7e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase superfamily Nop16 PF09420.10 OEU14245.1 - 0.095 12.7 1.6 0.17 11.9 1.6 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Nitroreductase PF00881.24 OEU14246.1 - 2.5e-05 24.4 0.0 6.2e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Nitroreductase family DUF1648 PF07853.11 OEU14249.1 - 0.028 14.1 0.0 0.094 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) DUF1043 PF06295.12 OEU14252.1 - 0.011 15.8 3.3 0.11 12.5 3.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) SARAF PF06682.12 OEU14252.1 - 0.015 15.0 0.5 0.015 15.0 0.5 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3450 PF11932.8 OEU14252.1 - 0.1 11.9 5.6 0.19 11.0 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1943 PF09172.11 OEU14252.1 - 0.67 9.1 4.6 1.1 8.4 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Presenilin PF01080.17 OEU14252.1 - 6.4 5.4 8.4 9.2 4.9 8.4 1.2 1 0 0 1 1 1 0 Presenilin DUF1635 PF07795.11 OEU14253.1 - 0.069 13.0 7.7 0.18 11.7 7.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Pro-MCH PF05824.12 OEU14253.1 - 0.091 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) RibD_C PF01872.17 OEU14253.1 - 0.13 12.0 1.8 0.13 12.1 0.5 1.6 2 0 0 2 2 2 0 RibD C-terminal domain DUF4224 PF13986.6 OEU14253.1 - 0.14 12.1 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Ly49 PF08391.10 OEU14253.1 - 0.44 10.9 5.9 1.4 9.3 4.2 2.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region MAP17 PF15807.5 OEU14253.1 - 2.2 8.5 0.0 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RusA PF05866.11 OEU14254.1 - 2.4e-06 28.1 0.0 4.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA DUF1180 PF06679.12 OEU14255.1 - 0.11 12.9 0.6 0.35 11.3 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 OEU14255.1 - 0.12 12.3 1.0 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family Syndecan PF01034.20 OEU14255.1 - 0.21 11.5 0.9 0.49 10.4 0.9 1.6 1 0 0 1 1 1 0 Syndecan domain Chordopox_A13L PF05961.11 OEU14255.1 - 4.8 7.5 6.2 14 6.0 6.2 2.0 1 1 0 1 1 1 0 Chordopoxvirus A13L protein CRAL_TRIO PF00650.20 OEU14256.1 - 0.028 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain ID PF18543.1 OEU14256.1 - 0.03 14.3 0.2 0.069 13.2 0.2 1.6 1 0 0 1 1 1 0 Intracellular delivery domain SWI-SNF_Ssr4 PF08549.10 OEU14256.1 - 4 5.9 11.3 5 5.6 11.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3446 PF11928.8 OEU14256.1 - 5.7 7.3 17.3 3.4 8.0 5.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain TMEM51 PF15345.6 OEU14257.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Ion_trans PF00520.31 OEU14257.1 - 0.061 12.5 0.6 0.11 11.7 0.6 1.4 1 0 0 1 1 1 0 Ion transport protein PalH PF08733.10 OEU14257.1 - 0.18 10.8 6.3 0.1 11.6 0.5 2.7 3 0 0 3 3 3 0 PalH/RIM21 PPTA PF01239.22 OEU14258.1 - 3.2e-09 36.2 7.1 0.0004 20.0 0.0 4.8 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat BSP_II PF05432.11 OEU14258.1 - 0.00036 20.3 6.7 0.00036 20.3 6.7 4.7 4 1 0 4 4 4 1 Bone sialoprotein II (BSP-II) Antistasin PF02822.14 OEU14259.1 - 0.0024 18.5 2.6 1.5 9.5 0.5 3.2 2 0 0 2 2 2 2 Antistasin family Myelin_PLP PF01275.19 OEU14259.1 - 0.023 14.6 0.0 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) LRR_8 PF13855.6 OEU14261.1 - 2e-05 24.2 2.2 3.2e-05 23.6 2.2 1.3 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 OEU14261.1 - 0.00021 21.4 4.8 0.096 13.3 0.2 3.1 2 1 1 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.7 OEU14261.1 - 0.0016 18.8 3.1 0.21 12.1 3.1 2.2 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU14261.1 - 0.16 12.1 1.0 5.4 7.3 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeat Peptidase_C14 PF00656.22 OEU14262.1 - 3.2e-44 151.7 0.9 2.2e-34 119.5 0.3 2.0 2 0 0 2 2 2 2 Caspase domain Peptidase_C13 PF01650.18 OEU14262.1 - 0.0065 16.0 3.5 0.76 9.2 0.4 2.4 1 1 1 2 2 2 2 Peptidase C13 family Raptor_N PF14538.6 OEU14262.1 - 0.036 14.0 0.1 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain TIP120 PF08623.10 OEU14263.1 - 1.2e-34 119.5 7.3 1.4e-31 109.5 0.1 5.9 5 2 1 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 OEU14263.1 - 1.1e-10 40.9 12.4 0.05 13.9 0.1 8.3 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 OEU14263.1 - 7.3e-08 32.7 1.3 0.25 11.7 0.0 6.8 5 2 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 OEU14263.1 - 9.7e-05 22.8 8.2 2.4 8.8 0.0 8.5 10 0 0 10 10 10 1 HEAT-like repeat Sec7_N PF12783.7 OEU14263.1 - 0.00041 20.3 3.0 6.7 6.6 0.0 5.1 4 1 1 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 OEU14263.1 - 0.012 15.6 0.1 11 6.2 0.0 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 OEU14263.1 - 0.037 14.2 0.6 26 5.1 0.0 4.5 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 OEU14263.1 - 0.05 13.5 0.0 17 5.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) CLASP_N PF12348.8 OEU14263.1 - 0.52 9.8 4.5 16 5.0 0.0 4.5 5 0 0 5 5 5 0 CLASP N terminal RIX1 PF08167.12 OEU14263.1 - 9.1 6.0 19.1 0.97 9.1 1.5 5.5 7 1 0 7 7 7 0 rRNA processing/ribosome biogenesis RVT_2 PF07727.14 OEU14264.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 OEU14264.1 - 0.038 14.4 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair HSF_DNA-bind PF00447.17 OEU14265.1 - 4.3e-13 49.7 0.1 4.8e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1430 PF07242.11 OEU14265.1 - 0.0031 17.8 0.4 0.0041 17.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1430) RasGAP PF00616.19 OEU14265.1 - 0.025 14.3 0.1 0.025 14.3 0.1 1.0 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase RCDG1 PF15725.5 OEU14266.1 - 0.39 11.2 3.8 0.82 10.1 0.4 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein SR-25 PF10500.9 OEU14266.1 - 3.2 7.3 7.3 5.3 6.6 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HMG_box PF00505.19 OEU14267.1 - 2.5e-10 40.6 15.9 2.5e-05 24.6 4.1 3.2 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU14267.1 - 1.6e-06 28.6 9.0 0.0023 18.5 0.5 2.6 2 1 0 2 2 2 2 HMG-box domain PGI PF00342.19 OEU14267.1 - 0.077 11.6 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase BNIP2 PF12496.8 OEU14267.1 - 2.7 8.4 6.2 3.5 8.0 6.2 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Eapp_C PF10238.9 OEU14268.1 - 0.14 12.2 1.1 0.17 12.0 1.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Coilin_N PF15862.5 OEU14268.1 - 0.65 9.8 9.4 1 9.1 9.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus SWIRM-assoc_2 PF16496.5 OEU14268.1 - 2.4 7.0 13.5 2.7 6.8 13.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal UPF0239 PF06783.11 OEU14268.1 - 2.7 8.2 7.9 5.3 7.3 7.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) VCX_VCY PF15231.6 OEU14270.1 - 0.00025 21.7 3.4 0.00056 20.6 3.4 1.5 1 0 0 1 1 1 1 Variable charge X/Y family Serglycin PF04360.12 OEU14270.1 - 0.024 14.6 1.3 0.031 14.2 0.1 1.8 2 0 0 2 2 2 0 Serglycin DUF1664 PF07889.12 OEU14272.1 - 7.5e-05 22.8 0.8 0.00014 21.9 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OEU14272.1 - 0.0035 17.4 1.0 0.0066 16.5 1.0 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DLP_helical PF18709.1 OEU14272.1 - 0.017 14.4 0.4 0.025 13.8 0.4 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain MscS_porin PF12795.7 OEU14272.1 - 0.041 13.4 0.8 0.041 13.4 0.8 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CorA PF01544.18 OEU14272.1 - 0.076 12.3 1.2 0.2 11.0 0.3 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.12 OEU14272.1 - 0.085 12.9 1.3 0.16 12.0 1.3 1.5 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 OEU14272.1 - 0.11 11.3 3.5 1.3 7.8 2.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 OEU14272.1 - 0.66 10.6 4.7 0.17 12.5 1.2 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3328 PF11807.8 OEU14274.1 - 0.32 10.7 1.6 0.42 10.4 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) CSRNP_N PF16019.5 OEU14274.1 - 0.66 9.8 2.9 0.47 10.3 0.2 1.8 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Mtc PF03820.17 OEU14275.1 - 2.7e-86 289.5 0.4 3.1e-86 289.3 0.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SRP9-21 PF05486.12 OEU14275.1 - 0.028 14.8 0.4 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Secretin_N_2 PF07655.13 OEU14275.1 - 0.46 11.1 8.1 0.52 10.9 4.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain PDGF_N PF04692.13 OEU14275.1 - 1 10.2 3.6 3.7 8.4 0.2 2.5 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region RRP14 PF15459.6 OEU14275.1 - 3.4 8.4 7.6 8.3 7.1 0.5 2.5 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 DUF3915 PF13054.6 OEU14277.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) Sec-ASP3 PF15432.6 OEU14277.1 - 0.041 14.0 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 ABC2_membrane_3 PF12698.7 OEU14278.1 - 0.0011 18.1 1.0 0.0014 17.8 1.0 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Apelin PF15360.6 OEU14279.1 - 0.14 12.7 0.1 0.35 11.4 0.1 1.7 1 0 0 1 1 1 0 APJ endogenous ligand UPF0560 PF10577.9 OEU14279.1 - 0.26 9.8 2.8 0.34 9.4 2.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.14 OEU14279.1 - 0.95 7.7 13.4 1.4 7.2 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OEU14279.1 - 2 6.5 20.3 2.7 6.0 20.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sulfotransfer_4 PF17784.1 OEU14280.1 - 2.6e-32 112.4 0.0 6.3e-32 111.2 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain CENP-T_N PF16171.5 OEU14282.1 - 5.5 5.8 9.7 13 4.6 9.4 1.6 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T N-terminus FHA PF00498.26 OEU14283.1 - 1.8e-05 25.0 0.0 4.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Clathrin_propel PF01394.20 OEU14283.1 - 0.0079 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Clathrin propeller repeat Folliculin PF11704.8 OEU14283.1 - 0.23 11.4 1.4 2.8 7.8 0.2 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Yae1_N PF09811.9 OEU14284.1 - 4.9e-13 48.5 111.7 1.5 8.6 0.4 25.8 11 6 13 25 25 25 14 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU14284.1 - 0.0034 17.5 2.0 68 3.5 0.0 5.8 5 1 0 6 6 6 2 Outer membrane protein beta-barrel domain adh_short PF00106.25 OEU14285.1 - 3.3e-26 92.0 0.0 2e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU14285.1 - 2.5e-11 43.6 0.0 9.2e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU14285.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 OEU14285.1 - 0.041 14.5 0.0 0.081 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Fer2 PF00111.27 OEU14286.1 - 5.3e-07 29.5 0.3 8.2e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 OEU14286.1 - 0.0021 18.0 0.6 0.0045 17.0 0.6 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-MYND PF01753.18 OEU14287.1 - 3e-07 30.4 7.5 7.3e-07 29.2 7.5 1.7 1 0 0 1 1 1 1 MYND finger LCM PF04072.14 OEU14288.1 - 1.3e-05 25.2 0.0 5.8e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 Leucine carboxyl methyltransferase Peripla_BP_4 PF13407.6 OEU14289.1 - 1e-54 185.9 9.1 9.3e-29 100.8 3.0 2.5 2 1 0 2 2 2 2 Periplasmic binding protein domain Internalin_N PF12354.8 OEU14289.1 - 0.0035 17.4 1.3 0.011 15.8 1.3 1.8 1 0 0 1 1 1 1 Bacterial adhesion/invasion protein N terminal TMEM169 PF15052.6 OEU14290.1 - 0.014 15.5 0.1 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 TMEM169 protein family Spore_YhaL PF14147.6 OEU14290.1 - 0.5 10.1 4.1 1.9 8.3 4.1 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL DUF2749 PF10907.8 OEU14290.1 - 0.52 10.5 2.5 0.93 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF3421 PF11901.8 OEU14292.1 - 0.053 13.5 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) RAMA PF18755.1 OEU14292.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated UQ_con PF00179.26 OEU14293.1 - 1.7e-15 56.9 0.0 4.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4 PF00097.25 OEU14293.1 - 1.7e-09 37.4 10.5 6.7e-09 35.5 10.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU14293.1 - 3.6e-09 36.3 11.7 1.2e-08 34.6 11.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU14293.1 - 5e-09 35.9 7.4 5e-09 35.9 7.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU14293.1 - 2.8e-07 30.5 8.9 3.2e-06 27.1 9.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU14293.1 - 3e-07 30.6 10.3 3e-07 30.6 10.3 2.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 OEU14293.1 - 3.7e-07 30.0 9.0 9.7e-07 28.6 9.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU14293.1 - 8.5e-07 28.7 9.3 1.9e-06 27.6 9.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OEU14293.1 - 0.00022 21.0 4.1 0.00069 19.4 4.1 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OEU14293.1 - 0.00095 18.9 4.0 0.00095 18.9 4.0 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OEU14293.1 - 0.0014 18.9 6.3 0.0061 16.8 6.3 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OEU14293.1 - 0.0014 18.7 10.2 0.0014 18.7 10.2 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OEU14293.1 - 0.0056 16.5 5.5 0.021 14.6 5.5 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OEU14293.1 - 0.022 14.8 3.4 0.075 13.1 3.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_5 PF17121.5 OEU14293.1 - 0.035 14.0 6.2 0.11 12.4 6.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF641 PF04859.12 OEU14293.1 - 0.18 12.2 1.0 0.35 11.2 1.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Sina PF03145.16 OEU14293.1 - 1 9.2 6.8 2.8 7.9 6.3 1.9 1 1 1 2 2 2 0 Seven in absentia protein family zf-RING_10 PF16685.5 OEU14293.1 - 2.3 8.4 7.8 7.7 6.7 7.8 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_8 PF13181.6 OEU14294.1 - 0.023 14.9 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU14294.1 - 0.026 14.6 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU14294.1 - 0.052 13.4 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU14294.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TFR_dimer PF04253.15 OEU14296.1 - 1.5e-18 67.0 7.2 4.9e-18 65.4 2.5 2.8 2 1 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OEU14296.1 - 4.2e-15 56.0 0.0 6.3e-13 48.9 0.0 2.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OEU14296.1 - 1.4e-09 37.8 0.0 4.7e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 PA domain DUF202 PF02656.15 OEU14297.1 - 0.46 11.0 4.5 0.29 11.6 1.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GlutR_N PF05201.15 OEU14298.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Pkinase_Tyr PF07714.17 OEU14299.1 - 2e-30 105.9 0.1 2.3e-30 105.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU14299.1 - 2.6e-26 92.6 0.0 3.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU14299.1 - 0.0049 15.7 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_7 PF13508.7 OEU14301.1 - 1e-05 25.8 0.0 2.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU14301.1 - 3.1e-05 23.9 0.0 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 OEU14301.1 - 0.0028 17.5 0.1 2.6 7.9 0.0 3.5 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU14301.1 - 0.0074 16.5 0.0 0.022 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OEU14301.1 - 0.21 11.7 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Mtc PF03820.17 OEU14302.1 - 1.3e-88 297.0 0.4 1.5e-88 296.8 0.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF3176 PF11374.8 OEU14302.1 - 0.12 12.6 0.4 0.27 11.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) DnaJ_C PF01556.18 OEU14303.1 - 0.00016 21.8 2.8 0.39 10.8 0.0 3.6 2 1 2 4 4 4 2 DnaJ C terminal domain RskA PF10099.9 OEU14303.1 - 0.00022 21.6 13.1 0.011 16.0 7.9 3.0 2 1 0 2 2 2 2 Anti-sigma-K factor rskA NfeD PF01957.18 OEU14303.1 - 0.00059 20.2 0.6 17 5.8 0.0 4.3 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding Ig_5 PF16681.5 OEU14303.1 - 0.00091 19.6 0.1 6.3 7.3 0.0 4.1 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 OEU14303.1 - 0.011 15.9 1.0 0.17 12.1 0.5 2.9 2 0 0 2 2 2 0 Immunoglobulin C2-set domain RseC_MucC PF04246.12 OEU14303.1 - 0.043 13.8 0.1 50 3.8 0.0 3.7 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC TRAF6_Z2 PF18048.1 OEU14303.1 - 0.13 12.4 2.4 39 4.5 0.2 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Ysc84 PF04366.12 OEU14303.1 - 0.49 10.1 0.0 0.49 10.1 0.0 3.1 2 1 0 2 2 1 0 Las17-binding protein actin regulator DUF4179 PF13786.6 OEU14303.1 - 0.74 10.3 6.9 33 5.0 4.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) FixH PF05751.11 OEU14303.1 - 2.1 8.3 6.5 1.1 9.3 0.9 2.7 2 1 1 3 3 3 0 FixH ANAPC1 PF12859.7 OEU14303.1 - 9.9 6.7 13.0 2.5 8.7 5.2 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Exo_endo_phos PF03372.23 OEU14304.1 - 0.00016 21.2 0.0 0.00043 19.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 OEU14304.1 - 0.00065 19.3 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GARS_A PF01071.19 OEU14304.1 - 0.03 14.1 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Orbi_NS3 PF01616.16 OEU14306.1 - 0.083 12.6 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Orbivirus NS3 XRCC4 PF06632.12 OEU14307.1 - 9 5.0 11.1 17 4.1 11.1 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 eIF3g PF12353.8 OEU14308.1 - 0.00016 22.1 0.3 0.00016 22.1 0.3 3.5 4 0 0 4 4 4 1 Eukaryotic translation initiation factor 3 subunit G LcrG PF07216.12 OEU14308.1 - 0.4 10.6 3.7 3.2 7.7 1.2 2.4 2 0 0 2 2 2 0 LcrG protein BHD_2 PF10404.9 OEU14308.1 - 2.2 9.3 4.4 22 6.1 0.1 3.5 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 2 MRPL52 PF18699.1 OEU14308.1 - 4.9 7.4 10.9 4.9 7.4 3.1 3.0 2 0 0 2 2 2 0 Mitoribosomal protein mL52 LRR_8 PF13855.6 OEU14309.1 - 2e-19 69.1 60.7 2.5e-06 27.2 4.3 4.8 2 1 6 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OEU14309.1 - 1.1e-15 57.4 29.1 0.00067 20.0 0.7 6.4 1 1 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14309.1 - 5.6e-06 26.2 20.7 12 6.9 0.1 9.6 8 2 1 9 9 9 3 Leucine Rich Repeat Notch PF00066.17 OEU14309.1 - 0.011 16.2 14.0 0.43 11.1 6.2 2.7 2 0 0 2 2 2 0 LNR domain Plk4_PB2 PF18409.1 OEU14309.1 - 0.026 15.2 0.2 0.068 13.9 0.2 1.7 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 APG9 PF04109.16 OEU14310.1 - 1.9e-94 317.4 0.7 3.6e-94 316.5 0.7 1.4 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF5326 PF17260.2 OEU14310.1 - 1.7 8.9 4.3 1.7 8.8 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) CRAL_TRIO PF00650.20 OEU14311.1 - 4.7e-13 49.2 0.1 1.2e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OEU14311.1 - 0.04 14.1 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain FG-GAP_2 PF14312.6 OEU14311.1 - 0.098 12.9 0.9 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 FG-GAP repeat KH_6 PF15985.5 OEU14315.1 - 1.9e-09 37.7 0.6 3.3e-09 37.0 0.6 1.4 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 OEU14315.1 - 2.6e-09 36.7 0.0 1.8e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Late_protein_L2 PF00513.18 OEU14317.1 - 4.8 6.1 12.5 2.6 7.0 11.0 1.2 1 1 0 1 1 1 0 Late Protein L2 TP53IP5 PF15331.6 OEU14317.1 - 8.5 6.5 12.3 6 6.9 10.5 1.7 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 tRNA_bind PF01588.20 OEU14318.1 - 1.8e-05 24.8 0.1 3.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Chloroa_b-bind PF00504.21 OEU14321.1 - 9.5e-35 120.5 0.1 1.2e-34 120.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SAP PF02037.27 OEU14322.1 - 8.7e-07 28.6 2.0 6.6e-06 25.8 0.2 2.5 2 0 0 2 2 2 1 SAP domain Peptidase_M66 PF10462.9 OEU14324.1 - 1.3e-60 205.0 4.1 5e-60 203.0 4.6 1.6 2 0 0 2 2 2 1 Peptidase M66 TagA PF12561.8 OEU14324.1 - 1.9e-24 85.9 0.1 5.5e-24 84.5 0.1 1.8 1 0 0 1 1 1 1 ToxR activated gene A lipoprotein domain SR-25 PF10500.9 OEU14324.1 - 0.0048 16.5 13.0 0.01 15.4 13.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Reprolysin_3 PF13582.6 OEU14324.1 - 0.11 13.0 3.1 0.52 10.8 1.2 2.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OEU14324.1 - 0.54 10.4 5.9 0.31 11.2 0.7 2.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 EF-hand_1 PF00036.32 OEU14325.1 - 4.2e-27 91.6 9.7 1.1e-05 24.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OEU14325.1 - 4.1e-25 86.1 9.7 1.3e-06 27.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OEU14325.1 - 6.9e-25 84.8 3.8 3e-05 23.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OEU14325.1 - 1.3e-23 82.5 3.9 5.4e-05 23.0 0.0 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 OEU14325.1 - 6.5e-23 81.0 3.0 4.3e-11 43.1 0.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU14325.1 - 0.00011 22.5 0.0 0.23 11.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OEU14325.1 - 0.0083 16.4 0.3 1.2 9.5 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 OEU14325.1 - 0.047 13.6 0.0 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 OEU14325.1 - 0.067 13.4 0.1 34 4.6 0.0 3.0 1 1 1 3 3 3 0 p25-alpha HOIP-UBA PF16678.5 OEU14325.1 - 0.2 11.6 0.0 27 4.7 0.0 2.2 2 0 0 2 2 2 0 HOIP UBA domain pair BolA PF01722.18 OEU14326.1 - 8.6e-12 45.2 0.1 1.6e-11 44.3 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein DUF3235 PF11574.8 OEU14327.1 - 0.45 11.4 3.6 0.42 11.5 0.2 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3235) SET PF00856.28 OEU14328.1 - 0.0087 16.5 0.1 0.032 14.6 0.1 2.0 1 1 0 1 1 1 1 SET domain bZIP_1 PF00170.21 OEU14330.1 - 8.3e-08 32.2 7.6 2.6e-07 30.6 7.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU14330.1 - 1.5e-07 31.4 6.4 6.1e-07 29.4 6.4 2.1 1 0 0 1 1 1 1 Basic region leucine zipper Phospholip_A2_2 PF05826.12 OEU14330.1 - 0.059 13.6 4.8 0.26 11.5 1.5 3.1 2 0 0 2 2 2 0 Phospholipase A2 Ank_5 PF13857.6 OEU14331.1 - 0.0037 17.6 0.0 0.52 10.7 0.1 3.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU14331.1 - 0.0055 17.2 0.1 1.3 9.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) MATH PF00917.26 OEU14332.1 - 3.2e-06 27.3 0.0 7.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 MATH domain Tudor_FRX1 PF18336.1 OEU14332.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain zf-RING_2 PF13639.6 OEU14333.1 - 1.4e-07 31.7 3.4 2.6e-07 30.9 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain Tmpp129 PF10272.9 OEU14333.1 - 0.0001 21.8 0.5 0.00026 20.4 0.5 1.7 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-RING_11 PF17123.5 OEU14333.1 - 0.00013 21.6 3.0 0.00024 20.8 3.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU14333.1 - 0.0013 18.5 3.2 0.0034 17.2 3.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU14333.1 - 0.0015 18.8 3.2 0.0043 17.3 3.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 OEU14333.1 - 0.0018 18.4 4.9 0.0033 17.6 4.9 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OEU14333.1 - 0.0077 16.2 1.7 0.0096 15.9 0.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU14333.1 - 0.016 15.1 3.0 0.032 14.2 3.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.6 OEU14333.1 - 0.016 15.1 7.1 0.019 14.9 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 OEU14333.1 - 0.018 15.1 3.3 0.07 13.2 3.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OEU14333.1 - 0.16 11.9 5.6 0.082 12.8 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU14333.1 - 0.53 10.2 7.1 1.6 8.6 7.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OEU14333.1 - 0.53 10.2 3.5 1.4 8.9 3.5 1.8 1 0 0 1 1 1 0 PHD-finger MAP17 PF15807.5 OEU14333.1 - 2.4 8.4 4.9 0.93 9.7 0.1 2.7 1 1 2 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 zf-RING_2 PF13639.6 OEU14334.1 - 8.6e-10 38.8 1.9 1.2e-09 38.3 1.9 1.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OEU14334.1 - 1.7e-07 31.1 1.0 7.5e-07 29.1 0.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OEU14334.1 - 3.8e-07 30.2 4.1 4.3e-07 30.0 4.1 1.1 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 OEU14334.1 - 5.2e-07 29.4 4.3 1.3e-06 28.1 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU14334.1 - 3.6e-06 26.6 4.6 6.3e-06 25.8 4.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OEU14334.1 - 8.7e-05 22.4 2.4 0.00031 20.6 2.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OEU14334.1 - 0.00022 21.4 5.6 0.0013 19.0 5.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU14334.1 - 0.00025 20.8 6.5 0.0093 15.8 6.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OEU14334.1 - 0.00057 19.8 3.7 0.0031 17.4 0.5 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 OEU14334.1 - 0.00068 19.4 3.4 0.0028 17.5 3.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU14334.1 - 0.0024 17.9 2.4 0.01 15.8 2.4 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OEU14334.1 - 0.0065 16.3 2.1 0.0076 16.0 0.3 1.9 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 OEU14334.1 - 0.028 14.0 4.1 0.048 13.3 4.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OEU14334.1 - 0.095 12.5 5.9 0.74 9.7 5.9 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OEU14334.1 - 0.11 12.4 3.4 0.19 11.6 3.4 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 OEU14334.1 - 0.12 12.4 1.1 0.12 12.4 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger zf-RING-like PF08746.11 OEU14334.1 - 0.47 10.8 7.2 3.5 8.0 7.2 2.3 1 1 0 1 1 1 0 RING-like domain DUF1664 PF07889.12 OEU14335.1 - 0.00039 20.5 3.0 0.00039 20.5 3.0 3.6 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 OEU14335.1 - 0.00043 20.2 7.7 0.00043 20.2 7.7 2.5 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 OEU14335.1 - 0.00066 18.4 10.8 0.001 17.8 10.8 1.2 1 0 0 1 1 1 1 Macoilin family LapA_dom PF06305.11 OEU14335.1 - 0.0041 16.9 0.2 0.01 15.6 0.2 1.7 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain HAP1_N PF04849.13 OEU14335.1 - 0.0071 15.6 15.4 0.0069 15.6 13.8 1.8 1 1 1 2 2 2 1 HAP1 N-terminal conserved region LPP PF04728.13 OEU14335.1 - 0.019 15.3 14.9 1.9 9.0 0.5 4.3 3 1 1 4 4 3 0 Lipoprotein leucine-zipper GAS PF13851.6 OEU14335.1 - 0.021 14.2 16.1 0.24 10.8 8.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 OEU14335.1 - 0.049 13.8 16.5 0.095 12.9 1.7 4.2 1 1 3 4 4 4 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 OEU14335.1 - 0.14 11.0 15.6 0.22 10.3 9.6 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 OEU14335.1 - 0.25 10.9 15.5 2.4 7.6 15.5 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit THOC7 PF05615.13 OEU14335.1 - 0.31 11.3 8.5 0.64 10.3 7.3 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 TMPIT PF07851.13 OEU14335.1 - 0.36 10.0 7.3 0.11 11.7 1.6 2.3 1 1 1 2 2 2 0 TMPIT-like protein DUF4200 PF13863.6 OEU14335.1 - 0.4 11.1 7.9 9 6.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MbeD_MobD PF04899.12 OEU14335.1 - 0.43 10.7 0.0 0.43 10.7 0.0 4.8 5 0 0 5 5 4 0 MbeD/MobD like FUSC PF04632.12 OEU14335.1 - 0.49 8.9 3.1 0.33 9.5 0.1 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF745 PF05335.13 OEU14335.1 - 0.54 10.0 4.8 1.1 9.0 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ERM PF00769.19 OEU14335.1 - 0.56 10.0 13.3 0.031 14.1 7.9 1.7 2 0 0 2 2 1 0 Ezrin/radixin/moesin family ZapB PF06005.12 OEU14335.1 - 0.76 10.3 25.4 0.34 11.4 4.3 4.5 1 1 3 4 4 3 0 Cell division protein ZapB HalX PF08663.10 OEU14335.1 - 0.92 9.9 3.8 6 7.3 1.0 3.3 2 2 1 3 3 3 0 HalX domain NPV_P10 PF05531.12 OEU14335.1 - 1.3 9.5 21.2 0.42 11.1 2.7 4.5 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 OEU14335.1 - 1.4 9.3 9.2 1.3 9.4 0.5 3.5 1 1 3 4 4 4 0 Uncharacterized conserved protein Cor1 PF04803.12 OEU14335.1 - 1.7 8.9 13.7 3.7 7.8 9.0 2.7 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region YabA PF06156.13 OEU14335.1 - 1.7 9.3 20.6 5.5 7.7 0.8 4.3 1 1 2 3 3 3 0 Initiation control protein YabA Sec34 PF04136.15 OEU14335.1 - 1.8 8.4 18.4 0.55 10.1 7.0 3.1 2 1 2 4 4 4 0 Sec34-like family Occludin_ELL PF07303.13 OEU14335.1 - 1.9 9.3 10.8 6.4 7.6 0.7 3.5 2 1 2 4 4 3 0 Occludin homology domain CEP63 PF17045.5 OEU14335.1 - 2.1 8.2 14.3 0.55 10.1 8.4 2.2 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF4164 PF13747.6 OEU14335.1 - 2.4 8.5 6.6 2.8 8.3 1.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) BAR_3 PF16746.5 OEU14335.1 - 2.4 7.8 16.7 1.4 8.5 10.0 2.9 1 1 2 3 3 3 0 BAR domain of APPL family bZIP_1 PF00170.21 OEU14335.1 - 2.6 8.2 16.3 2.5 8.3 1.1 4.1 2 1 1 4 4 4 0 bZIP transcription factor GCN5L1 PF06320.13 OEU14335.1 - 2.6 8.2 10.5 0.56 10.4 0.7 2.8 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) DivIVA PF05103.13 OEU14335.1 - 2.8 8.1 12.3 6.4 6.9 0.6 3.0 1 1 1 2 2 2 0 DivIVA protein HMMR_N PF15905.5 OEU14335.1 - 3.1 7.2 16.8 19 4.6 16.8 2.2 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 OEU14335.1 - 3.3 7.4 13.5 7.1 6.3 3.7 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 OEU14335.1 - 3.8 8.0 17.0 2.5 8.6 1.4 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 OEU14335.1 - 4.2 7.7 8.1 7.7 6.9 0.8 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Tup_N PF08581.10 OEU14335.1 - 4.3 7.7 9.8 2.6 8.4 3.5 3.3 1 1 0 2 2 2 0 Tup N-terminal ADIP PF11559.8 OEU14335.1 - 4.4 7.4 22.3 2.4 8.2 0.9 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 OEU14335.1 - 5.1 7.1 20.1 0.037 14.1 5.8 3.3 2 1 1 3 3 3 0 Laminin Domain II TMF_DNA_bd PF12329.8 OEU14335.1 - 6.9 6.7 13.9 1.1 9.3 0.3 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SAS4 PF15460.6 OEU14335.1 - 7.1 6.8 9.4 2.8 8.1 1.9 2.9 1 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF2205 PF10224.9 OEU14335.1 - 7.2 6.7 17.0 2.1 8.4 1.8 4.1 1 1 2 4 4 4 0 Short coiled-coil protein DUF948 PF06103.11 OEU14335.1 - 7.3 6.9 17.8 12 6.3 2.4 4.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 OEU14335.1 - 9 6.1 28.2 0.15 11.8 1.3 5.0 3 1 3 6 6 5 0 Septum formation initiator MIS13 PF08202.11 OEU14335.1 - 9.1 5.5 19.6 0.26 10.5 2.3 2.8 2 1 1 3 3 2 0 Mis12-Mtw1 protein family SPT16 PF08644.11 OEU14336.1 - 0.18 12.0 7.5 0.93 9.7 7.5 2.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) P3A PF08727.11 OEU14337.1 - 0.052 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like Na_Ca_ex_C PF16494.5 OEU14338.1 - 6.7 7.2 9.5 6.4 7.3 0.2 3.0 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain PT PF04886.12 OEU14339.1 - 5.7e-08 32.2 60.7 0.00042 19.8 21.7 3.7 1 1 2 3 3 3 3 PT repeat DUF1616 PF07760.11 OEU14340.1 - 0.019 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Serglycin PF04360.12 OEU14342.1 - 0.0011 18.9 3.8 0.0011 18.9 3.8 2.2 3 0 0 3 3 3 1 Serglycin Dirigent PF03018.14 OEU14343.1 - 0.011 15.6 0.2 0.021 14.7 0.2 1.4 1 0 0 1 1 1 0 Dirigent-like protein OB_NTP_bind PF07717.16 OEU14344.1 - 2.6e-15 56.5 0.1 6.2e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold rOmpB PF12334.8 OEU14344.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B 2_5_RNA_ligase2 PF13563.6 OEU14345.1 - 3.6e-09 36.7 0.0 1.8e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Neur_chan_memb PF02932.16 OEU14345.1 - 1.2 9.1 4.3 3.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 OEU14345.1 - 2.6 7.2 3.2 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter CRCB PF02537.15 OEU14346.1 - 0.00023 21.4 2.9 0.00033 20.9 3.0 1.4 1 1 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) SNARE PF05739.19 OEU14347.1 - 0.007 16.3 1.0 0.021 14.8 1.0 1.9 1 0 0 1 1 1 1 SNARE domain VP4_helical PF17478.2 OEU14347.1 - 0.0096 15.4 1.7 0.0096 15.4 1.7 3.0 2 1 1 3 3 3 1 Rotavirus VP4 helical domain V-SNARE_C PF12352.8 OEU14347.1 - 0.016 15.5 9.5 0.083 13.2 0.3 3.5 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 OEU14347.1 - 1.9 8.3 36.1 4.3 7.2 18.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) UPF0184 PF03670.13 OEU14347.1 - 5.9 7.4 10.0 15 6.0 0.4 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Aa_trans PF01490.18 OEU14349.1 - 6.7e-47 160.1 21.6 3.3e-37 128.2 10.2 3.0 3 0 0 3 3 3 2 Transmembrane amino acid transporter protein BUD22 PF09073.10 OEU14349.1 - 6.5e-05 22.4 1.3 9.9e-05 21.9 1.3 1.2 1 0 0 1 1 1 1 BUD22 FAM176 PF14851.6 OEU14349.1 - 0.0055 16.4 1.3 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 FAM176 family CENP-B_dimeris PF09026.10 OEU14349.1 - 0.31 11.5 24.6 0.12 12.8 6.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.12 OEU14349.1 - 0.89 8.9 7.6 2.3 7.5 7.6 1.6 1 1 0 1 1 1 0 SDA1 NOA36 PF06524.12 OEU14349.1 - 4.2 6.6 23.2 5.4 6.3 5.7 2.2 2 0 0 2 2 2 0 NOA36 protein Mem_trans PF03547.18 OEU14350.1 - 0.18 10.2 1.0 0.3 9.4 1.0 1.4 1 0 0 1 1 1 0 Membrane transport protein FlgH PF02107.16 OEU14350.1 - 1.8 8.2 9.0 0.17 11.5 0.4 2.8 2 0 0 2 2 2 0 Flagellar L-ring protein DUF3915 PF13054.6 OEU14350.1 - 6 6.9 13.7 0.5 10.4 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3915) PseudoU_synth_2 PF00849.22 OEU14351.1 - 2e-07 31.2 2.1 0.00063 19.9 1.1 4.8 3 2 0 3 3 3 2 RNA pseudouridylate synthase PC-Esterase PF13839.6 OEU14352.1 - 2.1e-07 31.0 10.3 8.6e-05 22.4 10.3 3.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p zf-RING_2 PF13639.6 OEU14353.1 - 3e-13 49.9 5.7 3.3e-13 49.7 5.7 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU14353.1 - 3.4e-11 42.8 5.6 4.2e-11 42.5 5.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU14353.1 - 4.9e-09 36.4 8.7 2.5e-08 34.1 8.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU14353.1 - 9.4e-09 35.0 3.1 1.3e-08 34.6 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU14353.1 - 5.3e-08 32.7 3.8 6.1e-08 32.5 3.8 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OEU14353.1 - 1.4e-07 31.1 3.3 2.4e-07 30.4 3.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OEU14353.1 - 7.7e-07 29.0 0.8 8.9e-07 28.8 0.2 1.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU14353.1 - 7.3e-06 25.8 3.7 1e-05 25.3 3.7 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OEU14353.1 - 1.5e-05 24.5 5.3 3.8e-05 23.2 5.3 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OEU14353.1 - 6.8e-05 23.0 7.1 0.0011 19.1 7.1 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 OEU14353.1 - 0.00013 22.0 5.6 0.00081 19.5 5.6 1.9 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 OEU14353.1 - 0.00029 20.6 5.8 0.0014 18.4 5.7 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 OEU14353.1 - 0.00038 20.7 3.7 0.00049 20.4 3.7 1.2 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 OEU14353.1 - 0.0014 18.6 5.1 0.0026 17.8 5.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YdjO PF14169.6 OEU14353.1 - 0.0021 17.8 0.2 0.74 9.6 0.0 2.1 2 0 0 2 2 2 2 Cold-inducible protein YdjO zf-C3H2C3 PF17122.5 OEU14353.1 - 0.016 15.3 5.7 0.07 13.2 5.7 2.1 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 OEU14353.1 - 0.044 13.7 4.5 0.069 13.1 4.5 1.4 1 1 0 1 1 1 0 PHD-finger zinc_ribbon_16 PF17034.5 OEU14353.1 - 0.1 12.8 3.4 0.13 12.4 1.2 1.8 1 1 1 2 2 2 0 Zinc-ribbon like family zf-P11 PF03854.14 OEU14353.1 - 0.33 10.6 6.1 1.2 8.9 6.1 1.8 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_1 PF14446.6 OEU14353.1 - 1.1 9.2 6.9 1.1 9.2 2.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 SHQ1 PF04925.15 OEU14354.1 - 3.5e-33 114.6 0.5 5.5e-33 114.0 0.5 1.2 1 0 0 1 1 1 1 SHQ1 protein BHD_2 PF10404.9 OEU14354.1 - 0.99 10.4 0.0 0.99 10.4 0.0 3.8 4 1 0 4 4 4 0 Rad4 beta-hairpin domain 2 Alk_phosphatase PF00245.20 OEU14357.1 - 1e-35 123.5 3.1 2.2e-16 59.8 0.1 3.1 3 0 0 3 3 3 3 Alkaline phosphatase Phosphodiest PF01663.22 OEU14357.1 - 0.0013 18.4 0.7 0.012 15.3 0.2 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OEU14357.1 - 0.0062 16.0 0.3 0.044 13.2 0.3 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 OEU14357.1 - 0.062 12.6 2.6 0.17 11.2 1.0 2.4 2 1 0 2 2 2 0 Metalloenzyme superfamily CRAL_TRIO PF00650.20 OEU14357.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain Sel1 PF08238.12 OEU14358.1 - 4.9e-10 39.7 0.1 1.8e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Sel1 repeat zf-MYND PF01753.18 OEU14358.1 - 1.7e-05 24.8 16.9 1.7e-05 24.8 16.9 3.5 4 1 0 4 4 4 1 MYND finger DUF525 PF04379.14 OEU14358.1 - 0.0026 18.0 0.0 0.0075 16.5 0.0 1.7 1 1 1 2 2 2 1 ApaG domain DUF1543 PF07566.12 OEU14358.1 - 0.093 12.5 0.2 0.89 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) Methyltransf_16 PF10294.9 OEU14359.1 - 1.8e-10 40.9 0.8 0.00065 19.5 0.0 2.7 1 1 0 2 2 2 2 Lysine methyltransferase Glycoprot_B_PH2 PF17417.2 OEU14360.1 - 3.7 7.9 6.1 1.3 9.4 1.1 2.3 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain RRP36 PF06102.12 OEU14360.1 - 6.3 6.7 17.9 1.1 9.2 4.8 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 zf-RING_2 PF13639.6 OEU14362.1 - 4.4e-10 39.7 8.3 4.4e-10 39.7 8.3 1.6 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU14362.1 - 3.9e-07 30.3 9.3 1.8e-06 28.2 9.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU14362.1 - 1e-05 25.2 7.7 1e-05 25.2 7.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU14362.1 - 2.3e-05 24.2 7.2 4.9e-05 23.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU14362.1 - 0.00014 21.5 7.1 0.00014 21.5 7.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 OEU14362.1 - 0.00056 19.8 7.3 0.001 19.0 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OEU14362.1 - 0.0038 17.2 2.6 0.0071 16.4 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OEU14362.1 - 0.0091 16.0 5.5 0.02 14.9 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 OEU14362.1 - 0.014 15.5 6.0 0.049 13.8 6.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OEU14362.1 - 0.25 11.2 6.0 0.85 9.5 6.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU14362.1 - 0.36 10.5 4.0 0.81 9.4 4.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU14362.1 - 0.42 10.5 7.3 0.92 9.4 7.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OEU14362.1 - 1.2 9.3 6.7 4.1 7.6 6.7 1.9 1 1 0 1 1 1 0 RING-variant domain SPX PF03105.19 OEU14362.1 - 1.4 8.8 11.1 2.4 8.0 11.1 1.5 1 1 0 1 1 1 0 SPX domain zf-RING-like PF08746.11 OEU14362.1 - 2.6 8.4 7.0 5.4 7.4 7.0 1.6 1 0 0 1 1 1 0 RING-like domain SID-1_RNA_chan PF13965.6 OEU14363.1 - 0.002 16.6 0.9 0.0024 16.3 0.9 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SAPS PF04499.15 OEU14363.1 - 0.0028 16.5 1.3 0.0033 16.3 1.3 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SCIMP PF15050.6 OEU14363.1 - 0.0056 17.1 1.7 0.0076 16.7 1.7 1.2 1 0 0 1 1 1 1 SCIMP protein RNA_polI_A34 PF08208.11 OEU14363.1 - 0.0068 16.5 20.1 0.0077 16.3 20.1 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 O-antigen_lig PF13425.6 OEU14363.1 - 0.007 15.2 1.1 0.0084 14.9 1.1 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Otopetrin PF03189.13 OEU14363.1 - 0.0073 15.2 0.1 0.0086 14.9 0.1 1.2 1 0 0 1 1 1 1 Otopetrin HemX PF04375.14 OEU14363.1 - 0.0086 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase WBP-1 PF11669.8 OEU14363.1 - 0.039 14.6 0.1 0.058 14.0 0.1 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 Serinc PF03348.15 OEU14363.1 - 0.064 12.2 0.2 0.067 12.1 0.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tetraspanin PF00335.20 OEU14363.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Zip PF02535.22 OEU14363.1 - 0.069 12.4 1.1 0.09 12.0 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 OEU14363.1 - 0.082 13.9 7.5 0.4 11.7 6.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) 7TM_GPCR_Str PF10326.9 OEU14363.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str OATP PF03137.20 OEU14363.1 - 0.14 10.4 3.0 0.23 9.7 3.0 1.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DcuA_DcuB PF03605.14 OEU14363.1 - 0.17 10.8 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter EMC3_TMCO1 PF01956.16 OEU14363.1 - 0.22 11.2 1.3 0.51 10.1 1.3 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4554 PF15091.6 OEU14363.1 - 1.9 7.3 8.4 2.5 6.9 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Connexin PF00029.19 OEU14363.1 - 3 7.5 8.9 10 5.8 8.9 1.8 1 1 0 1 1 1 0 Connexin CDC45 PF02724.14 OEU14363.1 - 5.3 5.2 20.9 6.6 4.9 20.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4366 PF14283.6 OEU14363.1 - 7.3 6.6 12.3 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) MAP17 PF15807.5 OEU14363.1 - 8.3 6.7 14.5 24 5.2 13.6 2.0 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ShK PF01549.24 OEU14364.1 - 0.006 17.1 10.4 0.011 16.2 0.2 3.1 3 1 0 3 3 3 2 ShK domain-like FERM_C PF09380.10 OEU14365.1 - 0.027 14.9 0.1 0.037 14.4 0.1 1.4 1 0 0 1 1 1 0 FERM C-terminal PH-like domain TMEM171 PF15471.6 OEU14366.1 - 0.0065 15.5 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein family 171 Aa_trans PF01490.18 OEU14368.1 - 5e-36 124.3 16.3 1.8e-16 59.9 0.3 4.2 3 1 1 4 4 4 4 Transmembrane amino acid transporter protein Sporozoite_P67 PF05642.11 OEU14368.1 - 0.00017 19.9 0.0 0.0007 17.8 0.0 1.9 2 1 1 3 3 3 1 Sporozoite P67 surface antigen MID_MedPIWI PF18296.1 OEU14368.1 - 0.032 14.0 8.4 0.89 9.3 0.2 3.1 3 0 0 3 3 3 0 MID domain of medPIWI LRRC37AB_C PF14914.6 OEU14368.1 - 0.065 13.1 0.1 0.065 13.1 0.1 3.6 4 0 0 4 4 4 0 LRRC37A/B like protein 1 C-terminal domain DUF2207 PF09972.9 OEU14368.1 - 0.17 10.6 0.3 6.4 5.4 0.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Cadherin_C_2 PF16492.5 OEU14368.1 - 0.23 12.2 8.9 23 5.8 0.6 4.6 4 1 0 4 4 4 0 Cadherin cytoplasmic C-terminal Sigma70_ECF PF07638.11 OEU14368.1 - 0.25 11.2 2.7 0.48 10.3 2.7 1.4 1 0 0 1 1 1 0 ECF sigma factor MscS_TM PF12794.7 OEU14368.1 - 0.63 8.9 4.0 3.7 6.3 0.0 3.5 3 1 1 4 4 4 0 Mechanosensitive ion channel inner membrane domain 1 PRRSV_2b PF07069.11 OEU14369.1 - 0.08 13.5 0.2 0.72 10.4 0.0 2.5 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b DUF3139 PF11337.8 OEU14369.1 - 0.14 12.8 0.1 1.1 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Herpes_UL35 PF04496.12 OEU14370.1 - 5.1 7.4 7.7 0.15 12.3 0.4 2.3 2 0 0 2 2 2 0 Herpesvirus UL35 family zf-C3HC4_3 PF13920.6 OEU14371.1 - 0.36 10.7 7.9 0.074 12.9 2.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhoD PF09423.10 OEU14373.1 - 4.7e-07 29.1 7.9 4.5e-05 22.6 7.9 3.2 1 1 0 1 1 1 1 PhoD-like phosphatase K_oxygenase PF13434.6 OEU14374.1 - 1.1e-20 74.1 0.2 1.4e-18 67.2 0.2 2.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OEU14374.1 - 1.9e-13 50.3 0.0 7.9e-12 45.0 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU14374.1 - 1.5e-05 25.1 0.0 0.71 9.8 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OEU14374.1 - 1.8e-05 24.2 0.1 0.061 12.6 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU14374.1 - 0.0041 16.8 0.0 7.4 6.0 0.0 3.4 3 1 1 4 4 4 1 FAD dependent oxidoreductase SR-25 PF10500.9 OEU14374.1 - 0.0094 15.6 13.3 0.022 14.4 13.3 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pyr_redox PF00070.27 OEU14374.1 - 0.014 15.9 0.0 0.044 14.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cwf_Cwc_15 PF04889.12 OEU14374.1 - 0.048 13.4 5.2 0.084 12.6 5.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Chorion_2 PF03964.15 OEU14374.1 - 0.073 13.9 2.4 0.17 12.7 2.4 1.6 1 0 0 1 1 1 0 Chorion family 2 TarS_C1 PF18674.1 OEU14374.1 - 0.092 12.7 0.5 0.17 11.8 0.1 1.6 2 0 0 2 2 2 0 TarS beta-glycosyltransferase C-terminal domain 1 NAD_binding_8 PF13450.6 OEU14374.1 - 0.14 12.4 3.8 1.7 8.9 0.1 3.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain BUD22 PF09073.10 OEU14374.1 - 3.4 6.9 12.0 5.1 6.3 12.0 1.1 1 0 0 1 1 1 0 BUD22 ATP_bind_3 PF01171.20 OEU14375.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 PP-loop family DUF1989 PF09347.10 OEU14376.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) Pneumo_NS1 PF03438.13 OEU14376.1 - 0.056 13.6 1.5 0.7 10.0 0.1 2.3 1 1 1 2 2 2 0 Pneumovirus NS1 protein RCC1_2 PF13540.6 OEU14378.1 - 0.28 11.0 1.3 0.35 10.7 0.2 1.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat TPR_10 PF13374.6 OEU14379.1 - 0.0088 15.9 0.5 0.041 13.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat RPA_interact_C PF14768.6 OEU14379.1 - 0.019 15.5 0.1 0.041 14.4 0.1 1.5 1 0 0 1 1 1 0 Replication protein A interacting C-terminal TPR_12 PF13424.6 OEU14379.1 - 0.023 15.0 0.1 0.086 13.1 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Prenyltransf PF01255.19 OEU14380.1 - 1.1e-50 172.3 2.5 2.3e-50 171.2 2.5 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Trypsin PF00089.26 OEU14381.1 - 4.5e-20 72.4 0.0 6.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin zf-MYND PF01753.18 OEU14382.1 - 2.3e-06 27.6 19.6 5.8e-06 26.3 19.6 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU14382.1 - 0.65 10.1 10.5 3.3 7.9 10.5 2.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 GDE_N PF12439.8 OEU14383.1 - 0.047 13.1 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Patatin PF01734.22 OEU14384.1 - 1.5e-07 31.8 0.5 7.5e-07 29.5 0.5 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase BshC PF10079.9 OEU14385.1 - 0.062 12.0 7.7 0.082 11.6 7.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC CDC45 PF02724.14 OEU14385.1 - 0.63 8.3 14.4 0.75 8.0 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein EMC3_TMCO1 PF01956.16 OEU14385.1 - 6.3 6.5 6.2 12 5.6 6.2 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RMI1_N PF08585.12 OEU14385.1 - 7.4 6.3 15.2 32 4.2 1.1 2.0 1 1 1 2 2 2 0 RecQ mediated genome instability protein Presenilin PF01080.17 OEU14385.1 - 7.5 5.2 14.1 9.4 4.9 14.1 1.2 1 0 0 1 1 1 0 Presenilin Bestrophin PF01062.21 OEU14386.1 - 8.8e-43 146.8 1.1 1.2e-42 146.3 1.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DctQ PF04290.12 OEU14386.1 - 0.47 10.4 9.0 1.2 9.1 0.2 2.8 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Bestrophin PF01062.21 OEU14387.1 - 1e-42 146.6 0.6 1.4e-42 146.1 0.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ATP-grasp_2 PF08442.10 OEU14388.1 - 1.6e-63 213.9 1.9 2.3e-63 213.4 1.9 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OEU14388.1 - 1.6e-26 92.9 1.9 4e-26 91.7 1.9 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OEU14388.1 - 6.9e-11 42.0 0.7 1.1e-10 41.4 0.7 1.2 1 0 0 1 1 1 1 ATP-grasp domain MIP PF00230.20 OEU14389.1 - 6.9e-35 120.8 14.3 9.3e-35 120.4 14.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF5134 PF17197.4 OEU14389.1 - 0.055 13.4 4.7 0.069 13.0 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) DUF285 PF03382.14 OEU14390.1 - 8.4e-225 732.5 165.3 7.5e-37 125.8 18.7 6.0 1 1 7 8 8 8 8 Mycoplasma protein of unknown function, DUF285 Csm2_III-A PF03750.13 OEU14390.1 - 0.00018 22.3 1.1 4.6 8.1 0.0 4.4 4 1 1 5 5 5 1 Csm2 Type III-A U5_2-snRNA_bdg PF10597.9 OEU14390.1 - 0.0019 18.3 36.2 5.2 7.1 0.1 9.5 1 1 9 11 11 11 3 U5-snRNA binding site 2 of PrP8 Phi29_Phage_SSB PF17427.2 OEU14390.1 - 0.019 15.1 8.7 0.9 9.7 0.1 4.5 5 0 0 5 5 5 0 Phage Single-stranded DNA-binding protein GATase_7 PF13537.6 OEU14390.1 - 0.026 14.4 0.1 3.3 7.6 0.0 2.8 2 0 0 2 2 2 0 Glutamine amidotransferase domain DDE_Tnp_IS1 PF03400.13 OEU14390.1 - 0.027 14.8 0.2 50 4.2 0.0 4.0 2 1 1 4 4 4 0 IS1 transposase FANCI_S1 PF14675.6 OEU14390.1 - 0.096 12.2 24.3 2.6 7.6 0.1 9.3 9 2 1 11 11 11 0 FANCI solenoid 1 NAD_synthase PF02540.17 OEU14390.1 - 0.17 11.0 1.2 6.1 5.9 0.2 2.5 2 1 0 2 2 2 0 NAD synthase DUF456 PF04306.13 OEU14392.1 - 0.0052 17.1 0.9 0.0052 17.1 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF456) MKT1_C PF12246.8 OEU14392.1 - 0.031 13.5 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DUF1269 PF06897.12 OEU14392.1 - 0.65 10.3 6.1 0.27 11.6 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 OEU14392.1 - 9.9 6.1 16.6 77 3.3 16.6 2.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Ubie_methyltran PF01209.18 OEU14393.1 - 1.4e-35 122.7 0.0 1.8e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU14393.1 - 6e-10 39.1 0.0 7.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU14393.1 - 8.1e-09 36.1 0.0 2.4e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU14393.1 - 6.3e-08 33.2 0.0 1.6e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU14393.1 - 9.9e-07 29.4 0.1 2.4e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU14393.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 OEU14393.1 - 0.0099 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 OEU14393.1 - 0.04 13.2 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 OEU14393.1 - 0.094 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TruB_N PF01509.18 OEU14395.1 - 2.3e-40 138.4 0.2 4.3e-40 137.5 0.2 1.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OEU14395.1 - 3e-07 30.5 0.1 6.3e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain bZIP_1 PF00170.21 OEU14396.1 - 0.0037 17.3 9.0 0.013 15.6 9.0 1.9 1 0 0 1 1 1 1 bZIP transcription factor Peptidase_S8 PF00082.22 OEU14397.1 - 3.2e-41 141.5 6.8 4.3e-41 141.1 6.8 1.2 1 0 0 1 1 1 1 Subtilase family PDZ PF00595.24 OEU14400.1 - 0.00013 22.3 4.5 0.01 16.2 0.0 3.3 3 0 0 3 3 3 1 PDZ domain Ribosomal_60s PF00428.19 OEU14400.1 - 0.00095 19.7 2.2 0.0014 19.1 0.8 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein PGPGW PF09656.10 OEU14400.1 - 0.0013 18.2 0.2 0.002 17.6 0.2 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) DUF3984 PF13136.6 OEU14400.1 - 0.0066 15.9 1.9 0.0066 15.9 1.9 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3984) CENP-B_dimeris PF09026.10 OEU14400.1 - 0.031 14.7 3.3 0.031 14.7 3.3 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PDZ_2 PF13180.6 OEU14400.1 - 0.05 13.9 0.2 11 6.5 0.0 2.8 2 0 0 2 2 2 0 PDZ domain Cytomega_UL84 PF06284.11 OEU14400.1 - 0.13 10.7 3.4 0.19 10.1 3.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Alpha-amyl_C PF09071.10 OEU14400.1 - 0.16 11.8 0.1 5.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Alpha-amylase, C terminal DUF719 PF05334.13 OEU14400.1 - 0.45 10.7 17.9 2 8.6 6.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF719) Phostensin PF13914.6 OEU14400.1 - 0.69 10.5 9.3 0.89 10.2 0.7 2.8 3 0 0 3 3 3 0 Phostensin PP1-binding and SH3-binding region PI3K_1B_p101 PF10486.9 OEU14400.1 - 0.91 7.2 9.4 0.023 12.5 2.8 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EIIBC-GUT_N PF03612.14 OEU14400.1 - 1.2 8.9 17.7 0.76 9.5 0.1 3.0 3 1 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.20 OEU14400.1 - 3.8 5.7 7.0 8.4 4.6 0.2 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ABC_tran PF00005.27 OEU14401.1 - 8e-43 146.2 0.1 5.7e-20 72.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OEU14401.1 - 1.7e-17 63.2 9.5 8.5e-17 61.0 8.4 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OEU14401.1 - 1.1e-16 61.5 3.9 0.00021 21.2 0.0 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OEU14401.1 - 2.4e-10 40.7 0.0 0.00057 19.7 0.5 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU14401.1 - 3.5e-07 29.9 0.1 0.04 13.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 OEU14401.1 - 8.1e-07 28.7 8.7 0.004 16.6 0.2 4.2 3 2 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OEU14401.1 - 3.4e-06 27.6 0.1 0.16 12.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OEU14401.1 - 1.3e-05 25.4 0.0 0.012 15.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU14401.1 - 2.8e-05 24.3 0.0 0.29 11.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OEU14401.1 - 4.1e-05 24.2 16.2 0.043 14.3 0.7 3.7 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 OEU14401.1 - 4.5e-05 23.4 5.7 0.0038 17.2 0.0 3.4 4 0 0 4 4 3 2 RsgA GTPase AAA_24 PF13479.6 OEU14401.1 - 6e-05 22.8 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OEU14401.1 - 0.00019 21.9 0.4 0.018 15.4 0.1 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OEU14401.1 - 0.00028 21.3 0.0 0.12 12.8 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 OEU14401.1 - 0.00037 20.9 0.2 0.049 14.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 OEU14401.1 - 0.00076 19.8 0.0 0.22 11.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OEU14401.1 - 0.0012 18.9 0.3 2 8.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 OEU14401.1 - 0.0014 18.6 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 OEU14401.1 - 0.0015 18.6 0.6 1.2 9.2 0.0 3.5 3 1 1 4 4 3 1 AAA domain SRP54 PF00448.22 OEU14401.1 - 0.0039 16.8 0.4 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 OEU14401.1 - 0.004 17.0 3.1 5.8 6.6 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OEU14401.1 - 0.0051 16.6 0.7 0.75 9.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OEU14401.1 - 0.0056 16.6 2.5 0.41 10.5 0.1 2.9 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.6 OEU14401.1 - 0.0088 15.6 0.0 0.56 9.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 OEU14401.1 - 0.0096 14.9 0.2 2.2 7.2 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 OEU14401.1 - 0.01 15.9 3.0 0.43 10.6 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain IstB_IS21 PF01695.17 OEU14401.1 - 0.012 15.4 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 OEU14401.1 - 0.022 14.7 0.0 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 OEU14401.1 - 0.031 13.8 0.0 5.1 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU14401.1 - 0.046 13.2 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 OEU14401.1 - 0.051 13.3 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Arf PF00025.21 OEU14401.1 - 0.062 12.8 1.5 2.7 7.4 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 OEU14401.1 - 0.063 13.0 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 OEU14401.1 - 0.088 13.2 0.0 30 5.0 0.1 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OEU14401.1 - 0.096 12.6 0.4 0.69 9.8 0.0 2.5 3 0 0 3 3 3 0 NTPase RuvB_N PF05496.12 OEU14401.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 OEU14401.1 - 1.2 8.7 5.5 2.3 7.8 0.1 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 OEU14401.1 - 1.2 8.5 5.7 7.9 5.9 0.1 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_13 PF13166.6 OEU14401.1 - 2 7.0 0.0 2 7.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain HSF_DNA-bind PF00447.17 OEU14402.1 - 1.3e-16 61.0 0.2 4.5e-16 59.3 0.2 2.0 1 0 0 1 1 1 1 HSF-type DNA-binding PIN_3 PF13470.6 OEU14402.1 - 0.046 14.5 0.3 0.16 12.8 0.1 1.9 1 1 1 2 2 2 0 PIN domain HSF_DNA-bind PF00447.17 OEU14403.1 - 4.2e-24 85.0 0.1 4.6e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DUF543 PF04418.12 OEU14405.1 - 5.7e-11 42.3 2.6 8.8e-11 41.6 2.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF543) Glycophorin_A PF01102.18 OEU14405.1 - 0.0075 16.5 0.1 0.011 16.0 0.1 1.2 1 0 0 1 1 1 1 Glycophorin A Gly-zipper_YMGG PF13441.6 OEU14405.1 - 0.0099 15.6 3.0 0.017 14.9 3.0 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper MotA_ExbB PF01618.16 OEU14405.1 - 0.017 14.9 0.2 0.13 12.0 0.0 2.2 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF5588 PF17826.1 OEU14405.1 - 0.032 13.1 0.9 0.034 13.0 0.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Rick_17kDa_Anti PF05433.15 OEU14405.1 - 0.47 10.4 7.2 0.71 9.8 7.2 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain NUDE_C PF04880.13 OEU14405.1 - 2.8 8.4 9.2 3.3 8.2 9.2 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region BUD22 PF09073.10 OEU14405.1 - 5.4 6.2 6.3 5.8 6.2 6.3 1.0 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 OEU14406.1 - 6e-16 58.6 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14406.1 - 0.00066 19.0 0.0 0.0063 15.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Methyltransf_22 PF13383.6 OEU14407.1 - 9.1e-79 264.6 3.0 1e-78 264.4 3.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OEU14407.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain PT PF04886.12 OEU14408.1 - 2.4e-08 33.4 72.4 5.6 6.6 4.6 5.7 3 1 0 3 3 3 1 PT repeat PARM PF17061.5 OEU14408.1 - 9.1 6.3 39.5 1.8 8.7 18.2 2.2 2 0 0 2 2 2 0 PARM DUF3446 PF11928.8 OEU14409.1 - 1.2 9.5 19.1 1.3 9.3 3.5 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Macoilin PF09726.9 OEU14409.1 - 1.9 6.9 7.6 2.5 6.6 7.6 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 OEU14409.1 - 4.9 7.0 16.1 3.9 7.4 3.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2975 PF11188.8 OEU14410.1 - 0.29 11.0 4.6 0.45 10.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2207 PF09972.9 OEU14410.1 - 0.54 8.9 3.6 0.18 10.6 0.9 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PT PF04886.12 OEU14413.1 - 1.6e-09 37.1 98.5 0.01 15.4 12.0 6.3 1 1 5 6 6 6 6 PT repeat LVIVD PF08309.11 OEU14413.1 - 7.6e-05 22.0 0.7 1.2 8.5 0.1 4.1 4 0 0 4 4 4 2 LVIVD repeat Gly_transf_sug PF04488.15 OEU14415.1 - 9.2e-09 35.8 0.3 9.2e-09 35.8 0.3 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU14415.1 - 0.00036 19.9 0.3 0.0031 16.9 0.0 2.1 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain FGE-sulfatase PF03781.16 OEU14419.1 - 2.2e-36 125.7 0.3 1.1e-33 117.0 0.1 2.7 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 PDT PF00800.18 OEU14421.1 - 0.024 14.5 0.6 0.032 14.1 0.6 1.2 1 0 0 1 1 1 0 Prephenate dehydratase MFAP1 PF06991.11 OEU14421.1 - 0.047 13.6 6.2 0.084 12.7 6.2 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing SSP160 PF06933.11 OEU14421.1 - 0.62 8.2 7.1 1 7.5 7.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CNDH2_M PF16869.5 OEU14421.1 - 3.7 8.2 7.4 5.3 7.7 7.2 1.4 1 1 0 1 1 1 0 PF16858 adh_short PF00106.25 OEU14424.1 - 5.2e-15 55.4 0.3 2.1e-12 46.9 0.3 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU14424.1 - 0.00025 21.0 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OEU14424.1 - 0.0041 16.7 0.1 0.37 10.3 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 OEU14424.1 - 0.015 15.0 0.9 0.045 13.5 0.2 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 OEU14424.1 - 0.07 13.2 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2306 PF10067.9 OEU14425.1 - 9.3e-05 22.7 3.3 0.00024 21.3 3.3 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) LapA_dom PF06305.11 OEU14425.1 - 0.011 15.6 5.5 0.5 10.2 0.3 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Aa_trans PF01490.18 OEU14426.1 - 4.4e-40 137.6 26.5 6.1e-40 137.2 26.4 1.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3789 PF12664.7 OEU14426.1 - 0.59 9.9 5.4 5.9 6.7 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) UPF0715 PF17094.5 OEU14426.1 - 0.84 10.2 10.6 0.085 13.4 5.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0715) YpjP PF14005.6 OEU14427.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 YpjP-like protein Tic22 PF04278.12 OEU14429.1 - 0.032 13.6 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Tic22-like family Terminase_4 PF05119.12 OEU14430.1 - 0.0025 18.2 0.3 0.0075 16.7 0.0 1.9 2 0 0 2 2 2 1 Phage terminase, small subunit PAF-AH_p_II PF03403.13 OEU14431.1 - 1.7e-20 72.9 0.9 6.4e-12 44.7 0.0 3.6 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 OEU14431.1 - 2.3e-07 30.7 0.7 0.00011 22.0 0.3 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OEU14431.1 - 9.5e-07 28.0 0.0 2.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 OEU14431.1 - 1.8e-06 27.6 1.0 0.0015 18.1 0.2 3.0 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OEU14431.1 - 6.2e-06 26.2 0.3 0.00063 19.6 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OEU14431.1 - 7.1e-06 25.5 0.7 0.1 11.8 0.0 3.2 2 1 1 3 3 3 3 Serine aminopeptidase, S33 DLH PF01738.18 OEU14431.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 OEU14431.1 - 0.0012 17.9 0.0 0.0048 16.0 0.0 1.9 3 0 0 3 3 3 1 Chlorophyllase Abhydrolase_1 PF00561.20 OEU14431.1 - 0.034 13.8 1.2 15 5.1 0.1 3.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold MLD PF11647.8 OEU14432.1 - 0.0037 17.5 0.3 3.9 7.8 0.0 2.6 2 0 0 2 2 2 2 Membrane Localization Domain 2OG-FeII_Oxy_3 PF13640.6 OEU14434.1 - 4.7e-15 56.2 0.0 1.9e-11 44.7 0.0 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU14434.1 - 4e-08 33.8 0.1 0.0011 19.5 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OEU14434.1 - 0.0066 16.8 0.0 0.082 13.3 0.0 2.7 3 0 0 3 3 3 1 Putative 2OG-Fe(II) oxygenase DUF2572 PF10833.8 OEU14434.1 - 0.0072 16.1 0.3 0.011 15.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2572) Head_binding PF09008.10 OEU14434.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Head binding SR-25 PF10500.9 OEU14434.1 - 1.5 8.4 15.2 2.5 7.6 15.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DSPc PF00782.20 OEU14435.1 - 7.8e-18 64.6 0.0 1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OEU14435.1 - 0.00046 19.8 0.5 0.0062 16.1 0.1 2.0 1 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OEU14435.1 - 0.0022 18.1 0.1 0.0058 16.7 0.1 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate C2 PF00168.30 OEU14436.1 - 1.2e-23 83.3 0.1 1.5e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 C2 domain Retrotran_gag_2 PF14223.6 OEU14437.1 - 0.00079 19.1 1.6 0.0015 18.2 0.1 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type RuvA_C PF07499.13 OEU14437.1 - 0.0032 17.9 0.7 4.3 7.9 0.4 2.6 2 0 0 2 2 2 2 RuvA, C-terminal domain IFT20 PF14931.6 OEU14437.1 - 0.031 14.4 1.8 0.047 13.9 0.5 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 SP_C-Propep PF08999.10 OEU14437.1 - 0.08 12.7 1.3 0.14 12.0 1.3 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tweety PF04906.13 OEU14437.1 - 0.13 10.9 3.2 0.26 9.9 1.0 1.9 1 1 1 2 2 2 0 Tweety SNF2_N PF00176.23 OEU14438.1 - 3.7e-36 124.6 0.8 6.5e-36 123.8 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU14438.1 - 2.1e-18 66.7 0.0 8e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU14438.1 - 6.7e-05 23.0 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OEU14438.1 - 0.00023 20.9 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 OEU14438.1 - 0.0046 16.2 0.0 0.014 14.6 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU14438.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase Rhodanese PF00581.20 OEU14438.1 - 0.029 14.9 0.0 13 6.4 0.0 2.5 2 0 0 2 2 2 0 Rhodanese-like domain AAA_22 PF13401.6 OEU14438.1 - 0.1 12.9 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain CRISPR_Cas9_WED PF18061.1 OEU14438.1 - 0.28 11.2 2.6 4.4 7.4 2.6 2.4 1 1 0 1 1 1 0 CRISPR-Cas9 WED domain PIEZO PF15917.5 OEU14440.1 - 2.9 7.3 12.6 0.25 10.8 7.4 1.9 2 1 0 2 2 2 0 Piezo DUF285 PF03382.14 OEU14441.1 - 1.1e-121 399.6 106.7 5.8e-33 113.2 23.6 4.7 1 1 4 5 5 5 5 Mycoplasma protein of unknown function, DUF285 SEFIR PF08357.11 OEU14441.1 - 2.5e-05 24.6 4.6 16 5.8 0.0 5.2 1 1 6 7 7 7 0 SEFIR domain T2SSF PF00482.23 OEU14441.1 - 0.015 15.2 0.7 6.6 6.7 0.2 3.7 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F DDE_Tnp_IS1 PF03400.13 OEU14441.1 - 0.042 14.2 0.1 15 5.9 0.0 3.5 1 1 2 4 4 4 0 IS1 transposase DUF445 PF04286.12 OEU14441.1 - 0.093 12.5 8.7 0.77 9.5 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Fimbrial_K88 PF02432.15 OEU14441.1 - 0.11 12.5 7.8 0.26 11.3 0.3 4.4 4 2 1 6 6 6 0 Fimbrial, major and minor subunit FANCI_S1 PF14675.6 OEU14441.1 - 0.22 11.1 21.3 10 5.6 0.4 7.5 4 2 4 8 8 8 0 FANCI solenoid 1 BRX_N PF13713.6 OEU14441.1 - 0.28 11.0 0.6 56 3.6 0.0 3.8 4 0 0 4 4 4 0 Transcription factor BRX N-terminal domain DUF3932 PF13068.6 OEU14441.1 - 0.47 10.8 51.2 1.1 9.6 0.4 10.1 2 1 10 12 12 12 0 Protein of unknown function (DUF3932) MecA_N PF05223.11 OEU14441.1 - 0.87 9.9 35.0 26 5.1 0.5 8.2 1 1 5 8 8 8 0 NTF2-like N-terminal transpeptidase domain SF3b10 PF07189.11 OEU14441.1 - 1.2 9.3 7.2 11 6.2 0.1 4.1 2 1 2 4 4 4 0 Splicing factor 3B subunit 10 (SF3b10) Nop PF01798.18 OEU14441.1 - 1.9 7.9 10.1 30 4.0 5.3 3.0 1 1 1 2 2 2 0 snoRNA binding domain, fibrillarin Death_2 PF14786.6 OEU14441.1 - 2.2 8.2 12.7 46 3.9 0.1 5.5 1 1 5 6 6 6 0 Tube Death domain Cytochrom_C_2 PF01322.20 OEU14441.1 - 3.6 8.5 21.3 4.3 8.2 0.1 4.4 1 1 3 4 4 4 0 Cytochrome C' Phage_rep_O PF04492.13 OEU14441.1 - 6.5 7.4 13.9 8.3 7.1 0.5 4.6 1 1 3 4 4 4 0 Bacteriophage replication protein O DUF2052 PF09747.9 OEU14442.1 - 0.00042 20.5 3.6 0.00076 19.7 3.6 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) PBP1_TM PF14812.6 OEU14442.1 - 0.0024 18.2 10.5 1.1 9.7 7.9 2.7 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OEU14442.1 - 0.012 15.3 12.6 0.044 13.5 3.4 2.6 3 0 0 3 3 3 0 FAM176 family Presenilin PF01080.17 OEU14442.1 - 0.19 10.5 2.1 0.28 9.9 2.1 1.2 1 0 0 1 1 1 0 Presenilin CSRNP_N PF16019.5 OEU14442.1 - 0.24 11.3 8.1 1 9.2 3.6 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Spt20 PF12090.8 OEU14442.1 - 1.3 8.6 16.5 0.11 12.2 8.1 2.3 2 0 0 2 2 2 0 Spt20 family RPN2_C PF18004.1 OEU14442.1 - 1.8 8.4 9.0 0.1 12.5 1.7 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 OEU14442.1 - 2.1 8.4 15.4 1.2 9.2 8.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 OEU14442.1 - 4.3 6.6 11.8 0.16 11.3 1.9 2.4 2 0 0 2 2 2 0 NOA36 protein DUF2956 PF11169.8 OEU14442.1 - 4.5 7.5 12.0 0.37 11.0 6.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) FYDLN_acid PF09538.10 OEU14442.1 - 6.7 7.4 15.5 3.6 8.3 8.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 OEU14442.1 - 9.3 4.2 11.9 17 3.4 11.9 1.3 1 1 0 1 1 1 0 DNA polymerase phi Ig_5 PF16681.5 OEU14443.1 - 0.055 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Phospholip_A2_3 PF09056.11 OEU14445.1 - 0.0047 17.5 0.2 0.013 16.1 0.2 1.7 1 1 0 1 1 1 1 Prokaryotic phospholipase A2 Myb_DNA-binding PF00249.31 OEU14447.1 - 1.6e-19 69.8 6.0 1.3e-09 38.1 1.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU14447.1 - 2.8e-13 49.9 4.7 5.9e-10 39.3 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Beta-lactamase PF00144.24 OEU14449.1 - 4.8e-10 39.2 0.0 8.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF98 PF01947.16 OEU14449.1 - 0.038 14.0 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 p-hydroxybenzoic acid synthase PT PF04886.12 OEU14450.1 - 1.2e-14 53.5 139.8 0.0029 17.1 12.2 9.6 5 3 1 6 6 6 2 PT repeat PSI PF01437.25 OEU14450.1 - 0.0082 16.7 4.9 0.016 15.7 4.9 1.5 1 0 0 1 1 1 1 Plexin repeat DUF677 PF05055.12 OEU14451.1 - 0.071 12.0 0.7 0.13 11.1 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF677) BSD PF03909.17 OEU14452.1 - 7.2e-09 35.5 2.9 6.1e-07 29.4 0.0 3.8 4 1 1 5 5 5 2 BSD domain MatE PF01554.18 OEU14454.1 - 0.0012 18.5 6.0 3.4 7.3 0.2 3.6 1 1 2 4 4 4 4 MatE XdhC_C PF13478.6 OEU14454.1 - 0.038 14.5 26.1 16 6.0 0.1 6.2 1 1 8 9 9 9 0 XdhC Rossmann domain LYTB PF02401.18 OEU14454.1 - 3.2 7.0 11.0 46 3.2 0.1 4.8 2 2 4 6 6 6 0 LytB protein MFS_1 PF07690.16 OEU14455.1 - 7e-16 58.1 22.5 1.1e-15 57.4 22.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU14456.1 - 4.5e-86 289.5 13.1 2.1e-61 208.2 4.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OEU14456.1 - 5.1e-33 114.5 17.4 2.2e-26 92.6 3.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 OEU14456.1 - 6.6e-06 25.1 0.1 1.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Reduced folate carrier Orf78 PF06024.12 OEU14456.1 - 0.0011 19.2 1.7 0.0033 17.7 1.0 2.2 1 1 0 1 1 1 1 Orf78 (ac78) MFS_2 PF13347.6 OEU14456.1 - 0.0023 16.5 0.7 0.0023 16.5 0.7 4.1 2 2 3 5 5 5 2 MFS/sugar transport protein zf-RING_2 PF13639.6 OEU14457.1 - 2.6e-14 53.2 7.8 3e-14 53.1 7.8 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU14457.1 - 1.1e-09 37.9 8.2 1.4e-09 37.7 8.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU14457.1 - 4.8e-08 32.6 5.2 7.4e-08 32.0 5.2 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU14457.1 - 1.4e-07 31.6 11.6 5.9e-07 29.7 11.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU14457.1 - 1.6e-07 31.1 7.4 2.1e-07 30.7 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU14457.1 - 1.6e-06 27.9 5.3 2e-06 27.7 5.3 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU14457.1 - 2.2e-06 27.4 5.3 2.8e-06 27.1 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU14457.1 - 4.3e-06 26.7 5.2 1.1e-05 25.4 5.3 1.6 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 OEU14457.1 - 6.3e-06 26.3 3.5 6.3e-06 26.3 3.5 2.2 1 1 1 2 2 2 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OEU14457.1 - 9.5e-05 22.0 4.9 0.00012 21.6 4.9 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OEU14457.1 - 0.00011 22.0 8.5 0.00027 20.7 8.5 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OEU14457.1 - 0.00016 21.6 6.1 0.0005 20.1 6.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 OEU14457.1 - 0.00033 20.2 1.1 0.00033 20.2 1.1 2.0 2 0 0 2 2 2 1 P-11 zinc finger RINGv PF12906.7 OEU14457.1 - 0.00051 20.1 6.9 0.0014 18.7 6.9 1.7 1 1 0 1 1 1 1 RING-variant domain Zf_RING PF16744.5 OEU14457.1 - 0.027 14.6 4.0 0.038 14.1 4.0 1.4 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 OEU14457.1 - 0.031 14.6 5.2 0.042 14.2 5.2 1.2 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 OEU14457.1 - 0.038 13.9 6.9 0.039 13.9 2.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OEU14457.1 - 0.26 11.2 8.4 0.59 10.1 8.4 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 OEU14457.1 - 0.67 10.0 9.0 2.6 8.2 9.0 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 OEU14457.1 - 0.68 9.8 10.2 3.4 7.5 10.3 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.12 OEU14458.1 - 0.01 13.9 11.6 0.013 13.6 11.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Activator_LAG-3 PF11498.8 OEU14458.1 - 0.15 11.0 27.4 0.23 10.4 27.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Hydin_ADK PF17213.3 OEU14458.1 - 1.2 9.4 6.3 1.4 9.1 6.3 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MraZ PF02381.18 OEU14458.1 - 1.7 8.7 5.0 7.1 6.7 5.0 2.0 1 1 0 1 1 1 0 MraZ protein, putative antitoxin-like Presenilin PF01080.17 OEU14458.1 - 3.3 6.4 7.8 3.7 6.2 7.8 1.1 1 0 0 1 1 1 0 Presenilin DUF5008 PF16400.5 OEU14459.1 - 0.062 13.4 0.3 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5008) DUF2116 PF09889.9 OEU14459.1 - 0.14 12.2 0.7 0.3 11.1 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SpoIIE PF07228.12 OEU14462.1 - 2.1e-06 27.8 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OEU14462.1 - 0.00054 19.7 0.2 1 8.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C DUF5643 PF18705.1 OEU14463.1 - 0.0069 16.3 1.9 0.012 15.6 1.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5643) TFIIF_beta_N PF17683.1 OEU14463.1 - 0.059 14.1 1.0 0.084 13.6 1.0 1.3 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus SnoaL_3 PF13474.6 OEU14464.1 - 1.5e-16 60.7 0.2 3.6e-09 36.9 0.0 2.5 2 1 0 2 2 2 2 SnoaL-like domain CaMKII_AD PF08332.10 OEU14464.1 - 2.7e-16 59.9 0.0 2e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 OEU14464.1 - 5e-10 39.7 0.0 3.2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 OEU14464.1 - 2.4e-08 34.1 0.3 0.037 14.2 0.0 3.1 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_2 PF12680.7 OEU14464.1 - 1.8e-06 28.5 0.0 7.8e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain DUF3225 PF11533.8 OEU14464.1 - 0.01 15.5 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) EAV_GS PF01309.18 OEU14464.1 - 0.02 14.5 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein DUF2911 PF11138.8 OEU14464.1 - 0.022 14.6 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2911) SNF PF00209.18 OEU14466.1 - 1.9e-90 304.1 37.2 3e-89 300.1 37.2 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4126 PF13548.6 OEU14468.1 - 4e-17 62.5 14.8 8.3e-17 61.4 14.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) VHP PF02209.19 OEU14468.1 - 6.5e-10 38.9 1.4 1.1e-09 38.1 1.4 1.4 1 0 0 1 1 1 1 Villin headpiece domain DUF5383 PF17355.2 OEU14469.1 - 3.4 8.1 5.8 2.2 8.7 1.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) PDZ PF00595.24 OEU14470.1 - 2.8e-14 53.2 2.9 8.7e-05 22.8 0.0 3.8 3 1 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OEU14470.1 - 8.2e-11 42.1 3.2 0.0016 18.8 0.2 4.3 3 1 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 OEU14470.1 - 6.4e-10 38.7 0.2 0.071 13.0 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 OEU14470.1 - 4.9e-05 23.2 2.9 0.056 13.4 0.0 3.9 5 0 0 5 5 5 2 Tricorn protease PDZ domain AIF_C PF14721.6 OEU14470.1 - 0.009 16.4 3.5 0.009 16.4 3.5 1.8 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Neugrin PF06413.11 OEU14470.1 - 0.052 13.6 2.4 0.12 12.3 2.4 1.6 1 0 0 1 1 1 0 Neugrin SOBP PF15279.6 OEU14470.1 - 0.061 13.9 13.0 0.14 12.8 9.8 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein PulA_N1 PF17999.1 OEU14470.1 - 2.3 9.0 13.9 22 5.9 0.1 4.3 2 1 2 4 4 4 0 Pullulanase N1-terminal domain DUF3949 PF13133.6 OEU14471.1 - 1.4 9.4 6.2 13 6.3 4.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) PAF PF15715.5 OEU14472.1 - 0.016 15.8 0.9 0.21 12.2 0.0 2.8 3 0 0 3 3 3 0 PCNA-associated factor histone like domain HAD PF12710.7 OEU14473.1 - 2.4e-13 50.9 0.0 6.8e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU14473.1 - 7.4e-11 42.7 0.5 3.2e-10 40.6 0.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OEU14473.1 - 4.6e-06 26.2 0.0 8.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OEU14473.1 - 0.00018 21.1 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Arc_trans_TRASH PF08394.10 OEU14474.1 - 0.014 15.7 0.2 0.039 14.3 0.2 1.7 1 0 0 1 1 1 0 Archaeal TRASH domain Citrus_P18 PF05520.11 OEU14474.1 - 0.097 12.4 7.2 0.024 14.4 2.6 1.9 2 0 0 2 2 2 0 Citrus tristeza virus P18 protein RSN1_7TM PF02714.15 OEU14475.1 - 5.8e-48 163.6 21.8 1.3e-47 162.5 21.8 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OEU14475.1 - 8.3e-29 100.4 0.3 8.3e-29 100.4 0.3 3.7 3 1 0 3 3 3 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OEU14475.1 - 3e-07 30.8 0.0 0.062 13.5 0.0 3.3 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DUF1757 PF08560.10 OEU14475.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) HA PF03457.14 OEU14476.1 - 6.9e-27 93.6 3.5 1.4e-12 47.7 0.3 2.8 2 0 0 2 2 2 2 Helicase associated domain OATP PF03137.20 OEU14476.1 - 1.9 6.7 3.4 2.6 6.2 3.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3304 PF11745.8 OEU14476.1 - 5.2 7.5 13.2 9.3 6.7 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3304) Peptidase_S9 PF00326.21 OEU14478.1 - 7.6e-40 136.6 0.0 8.4e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OEU14478.1 - 4.1e-07 29.9 0.5 0.00022 20.9 0.4 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OEU14478.1 - 5.9e-05 22.7 0.0 0.00025 20.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OEU14478.1 - 0.011 15.1 0.1 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OEU14478.1 - 0.013 15.3 0.1 3.6 7.3 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 OEU14478.1 - 0.015 15.0 0.1 0.057 13.1 0.1 2.0 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 OEU14478.1 - 0.015 14.9 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3141 PF11339.8 OEU14478.1 - 0.017 13.6 0.2 0.02 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) AXE1 PF05448.12 OEU14478.1 - 0.017 13.8 0.1 0.033 12.9 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OEU14478.1 - 0.043 14.4 0.0 0.059 14.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU14478.1 - 0.059 13.0 0.3 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 OEU14478.1 - 0.23 10.2 0.2 0.32 9.7 0.2 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DPPIV_N PF00930.21 OEU14479.1 - 4.2e-56 190.2 0.8 6.1e-56 189.7 0.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region adh_short PF00106.25 OEU14480.1 - 3.9e-11 42.8 4.1 5.1e-06 26.1 0.1 3.1 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU14480.1 - 0.0048 16.5 0.5 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase EMC3_TMCO1 PF01956.16 OEU14480.1 - 0.018 14.8 0.1 0.13 12.0 0.1 2.1 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Rsd_AlgQ PF04353.13 OEU14481.1 - 0.003 17.5 2.6 0.0041 17.1 0.5 1.9 2 0 0 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ F-box PF00646.33 OEU14482.1 - 7.5e-06 25.7 0.2 3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OEU14482.1 - 0.00043 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OEU14482.1 - 0.0005 19.9 0.1 0.0039 17.1 0.0 2.5 3 0 0 3 3 3 1 F-box PAP_assoc PF03828.19 OEU14483.1 - 0.085 13.1 0.1 13 6.1 0.0 3.0 2 0 0 2 2 2 0 Cid1 family poly A polymerase ABC1 PF03109.16 OEU14484.1 - 6.3e-14 52.2 0.0 8.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 ABC1 family DUF2971 PF11185.8 OEU14485.1 - 0.023 15.8 1.6 0.42 11.8 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2971) SnoaL_2 PF12680.7 OEU14486.1 - 0.013 16.1 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Gly-zipper_YMGG PF13441.6 OEU14488.1 - 0.43 10.4 17.5 0.11 12.2 3.5 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 OEU14488.1 - 9.2 6.5 13.2 17 5.6 3.6 2.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4366 PF14283.6 OEU14489.1 - 0.061 13.4 0.4 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) ADP_ribosyl_GH PF03747.14 OEU14489.1 - 0.47 10.1 5.6 15 5.2 5.1 2.4 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Zip PF02535.22 OEU14490.1 - 0.47 9.6 1.7 0.86 8.7 1.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OEU14490.1 - 0.59 8.8 3.3 1.1 8.0 3.3 1.4 1 0 0 1 1 1 0 Presenilin Otopetrin PF03189.13 OEU14490.1 - 1.5 7.6 7.3 8 5.2 0.1 2.2 2 0 0 2 2 2 0 Otopetrin Menin PF05053.13 OEU14490.1 - 2.7 6.3 10.3 4.7 5.5 10.3 1.3 1 0 0 1 1 1 0 Menin NST1 PF13945.6 OEU14490.1 - 4.2 7.4 19.0 2.4 8.2 13.7 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator MMR_HSR1 PF01926.23 OEU14491.1 - 1.6e-13 50.7 0.0 3.5e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU14491.1 - 0.0044 16.6 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU14491.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Dynamin family BRX_N PF13713.6 OEU14491.1 - 0.11 12.2 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain ABC_tran PF00005.27 OEU14491.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Pinin_SDK_N PF04697.13 OEU14491.1 - 0.19 12.4 0.3 0.91 10.2 0.0 1.9 2 0 0 2 2 2 0 pinin/SDK conserved region DJ-1_PfpI PF01965.24 OEU14492.1 - 9e-21 74.4 0.0 7.5e-20 71.4 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OEU14492.1 - 0.036 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like SNF2_N PF00176.23 OEU14496.1 - 9.6e-27 93.6 0.0 1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU14497.1 - 4e-17 62.6 0.0 6.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU14497.1 - 0.00013 21.3 0.2 0.00023 20.4 0.2 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UBN_AB PF14075.6 OEU14497.1 - 0.025 14.3 5.0 0.76 9.5 0.5 2.3 2 0 0 2 2 2 0 Ubinuclein conserved middle domain FAM176 PF14851.6 OEU14497.1 - 0.036 13.7 9.5 0.6 9.8 4.4 2.7 2 1 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 OEU14497.1 - 1.8 6.6 22.5 0.93 7.5 14.8 2.2 2 0 0 2 2 2 0 DNA polymerase phi DUF285 PF03382.14 OEU14498.1 - 2.1e-83 276.0 50.2 8e-32 109.6 12.9 3.0 1 1 2 3 3 3 3 Mycoplasma protein of unknown function, DUF285 Tubulin-binding PF00418.19 OEU14498.1 - 0.0033 17.4 4.4 12 6.1 0.0 5.2 6 0 0 6 6 6 1 Tau and MAP protein, tubulin-binding repeat Spo0A_C PF08769.11 OEU14498.1 - 0.15 12.1 5.6 1.1e+02 2.9 0.0 5.4 2 1 4 6 6 6 0 Sporulation initiation factor Spo0A C terminal Dicistro_VP4 PF11492.8 OEU14498.1 - 0.16 12.0 0.1 59 3.7 0.0 3.3 3 0 0 3 3 3 0 Cricket paralysis virus, VP4 Amidase PF01425.21 OEU14499.1 - 7.9e-53 180.0 0.0 3.4e-52 177.9 0.0 1.9 1 1 0 1 1 1 1 Amidase DUF2371 PF10177.9 OEU14499.1 - 0.19 11.9 1.2 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF5423 PF17461.2 OEU14499.1 - 9.9 4.9 11.3 16 4.2 11.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) MTP18 PF10558.9 OEU14500.1 - 2.1e-05 24.6 6.1 0.0024 17.9 1.9 2.9 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Fe_bilin_red PF05996.12 OEU14501.1 - 7e-12 45.5 0.1 6.1e-10 39.2 0.1 3.7 3 1 1 4 4 4 2 Ferredoxin-dependent bilin reductase Vma12 PF11712.8 OEU14501.1 - 0.09 12.8 0.0 0.09 12.8 0.0 2.7 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Zip PF02535.22 OEU14501.1 - 4.5 6.4 6.6 8.2 5.5 0.8 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Patatin PF01734.22 OEU14505.1 - 1.6e-09 38.2 0.3 6.1e-09 36.3 0.3 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase T2SSJ PF11612.8 OEU14505.1 - 0.079 13.2 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J Ank_2 PF12796.7 OEU14506.1 - 0.00079 20.0 0.0 0.0061 17.1 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) DUF2718 PF10918.8 OEU14506.1 - 1.7 9.2 7.9 14 6.2 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2718) Borealin PF10512.9 OEU14507.1 - 1.9e-11 44.0 1.5 0.0001 22.2 0.0 2.9 3 0 0 3 3 3 2 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 OEU14507.1 - 0.0038 16.8 0.7 0.0083 15.7 0.0 2.0 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal COP-gamma_platf PF08752.10 OEU14510.1 - 2e-12 47.5 0.0 4.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Vps39_2 PF10367.9 OEU14510.1 - 1.6e-05 25.3 0.3 4.6e-05 23.8 0.3 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 SUIM_assoc PF16619.5 OEU14510.1 - 0.014 15.5 0.1 0.014 15.5 0.1 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TPR_14 PF13428.6 OEU14510.1 - 0.4 11.6 1.4 8.5 7.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 OEU14511.1 - 7.3e-05 23.3 0.1 0.00029 21.4 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU14511.1 - 0.0036 17.7 0.0 0.018 15.6 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OEU14511.1 - 0.021 15.2 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Spt5-NGN PF03439.13 OEU14511.1 - 0.06 13.2 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Ank PF00023.30 OEU14511.1 - 0.1 13.1 0.0 0.45 11.1 0.0 2.1 3 0 0 3 3 3 0 Ankyrin repeat PP-binding_2 PF14573.6 OEU14511.1 - 0.12 12.6 0.9 5.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Acyl-carrier PAP2 PF01569.21 OEU14515.1 - 1.5e-14 53.9 1.4 1.5e-14 53.9 1.4 2.5 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 OEU14515.1 - 7.1e-08 32.4 3.2 1.1e-06 28.4 1.7 2.4 1 1 1 2 2 2 1 PAP2 superfamily DUF5389 PF17364.2 OEU14515.1 - 0.25 11.4 4.4 1.7 8.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5389) DUF2570 PF10828.8 OEU14516.1 - 0.01 15.6 0.4 0.017 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Pho88 PF10032.9 OEU14516.1 - 0.045 13.0 5.5 0.13 11.5 0.1 2.6 1 1 2 3 3 3 0 Phosphate transport (Pho88) DUF4064 PF13273.6 OEU14517.1 - 0.0023 18.2 3.4 2.2 8.6 2.6 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF4064) Sec20 PF03908.13 OEU14517.1 - 0.0049 16.8 0.5 0.08 12.9 0.1 2.4 2 0 0 2 2 2 1 Sec20 Serinc PF03348.15 OEU14517.1 - 0.59 9.0 8.1 0.58 9.0 6.4 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) COesterase PF00135.28 OEU14518.1 - 4.5e-55 187.5 0.5 5.5e-55 187.2 0.5 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OEU14518.1 - 5.1e-09 36.3 0.0 2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU14518.1 - 0.027 14.0 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 OEU14518.1 - 0.084 12.5 0.0 4.8 6.7 0.0 2.0 2 0 0 2 2 2 0 Putative esterase CD99L2 PF12301.8 OEU14519.1 - 0.078 13.3 7.1 0.12 12.7 7.1 1.5 1 1 0 1 1 1 0 CD99 antigen like protein 2 DUF1168 PF06658.12 OEU14519.1 - 0.76 9.6 17.1 1.2 9.0 17.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) XRN_M PF17846.1 OEU14519.1 - 5.4 5.9 9.4 5 6.0 9.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Choline_transpo PF04515.12 OEU14520.1 - 3.8e-67 226.8 43.1 3.8e-67 226.8 43.1 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter Sulfotransfer_2 PF03567.14 OEU14521.1 - 9e-15 55.3 18.5 3e-12 47.0 5.3 3.2 2 1 1 3 3 3 2 Sulfotransferase family DUF1657 PF07870.11 OEU14521.1 - 0.028 14.3 1.3 0.047 13.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) LAM_C PF12544.8 OEU14521.1 - 0.38 10.9 3.7 1 9.5 3.7 1.8 1 0 0 1 1 1 0 Lysine-2,3-aminomutase UPF0175 PF03683.13 OEU14522.1 - 5.1e-08 32.5 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0175) HTH_50 PF18024.1 OEU14522.1 - 6e-08 32.2 0.3 0.0013 18.3 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_24 PF13412.6 OEU14522.1 - 2.3e-06 27.1 0.1 0.037 13.6 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding DisA-linker PF10635.9 OEU14522.1 - 0.00044 20.0 0.2 0.18 11.6 0.0 2.4 3 0 0 3 3 3 2 DisA bacterial checkpoint controller linker region HTH_AsnC-type PF13404.6 OEU14522.1 - 0.00098 18.9 0.1 0.89 9.4 0.0 2.1 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_8 PF02954.19 OEU14522.1 - 0.0037 17.0 1.4 0.68 9.8 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, Fis family DUF1351 PF07083.11 OEU14522.1 - 0.012 15.4 0.8 0.013 15.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) HTH_37 PF13744.6 OEU14522.1 - 0.016 15.1 0.1 3 7.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 OEU14522.1 - 0.02 14.6 0.1 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4859 PF16151.5 OEU14522.1 - 0.035 14.0 0.2 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) DUF739 PF05339.11 OEU14522.1 - 0.035 14.3 0.8 4.7 7.4 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF739) HTH_29 PF13551.6 OEU14522.1 - 0.051 13.6 0.0 8.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_19 PF12844.7 OEU14522.1 - 0.061 13.4 0.2 15 5.7 0.0 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain DUF4269 PF14091.6 OEU14522.1 - 0.088 13.0 0.1 10 6.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4269) HTH_31 PF13560.6 OEU14522.1 - 0.15 12.4 0.0 5.2 7.5 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain PEX-2N PF09263.10 OEU14522.1 - 0.15 12.4 0.0 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Aldo_ket_red PF00248.21 OEU14524.1 - 5.4e-36 124.3 0.0 6.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Transpeptidase PF00905.22 OEU14524.1 - 0.0055 15.9 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain DUF1189 PF06691.11 OEU14525.1 - 0.009 15.6 0.9 0.013 15.1 0.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1189) SLM4 PF16818.5 OEU14525.1 - 0.044 13.8 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein SLM4 Cwf_Cwc_15 PF04889.12 OEU14525.1 - 1.2 8.8 5.9 1.8 8.2 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BAF1_ABF1 PF04684.13 OEU14526.1 - 3.1 6.7 32.1 1.9 7.4 14.0 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor COX6A PF02046.15 OEU14527.1 - 1.9e-07 31.5 0.3 3.6e-07 30.6 0.3 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Clathrin_lg_ch PF01086.17 OEU14528.1 - 6.3e-18 65.7 5.4 8.2e-18 65.3 5.4 1.2 1 0 0 1 1 1 1 Clathrin light chain adh_short_C2 PF13561.6 OEU14529.1 - 6.1e-61 206.0 0.8 7.3e-61 205.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU14529.1 - 3.1e-56 189.9 1.8 3.6e-56 189.7 1.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU14529.1 - 1.2e-20 74.2 0.8 1.7e-20 73.7 0.8 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OEU14529.1 - 0.018 14.5 0.0 0.076 12.4 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OEU14529.1 - 0.054 12.9 0.1 0.14 11.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 OEU14529.1 - 0.095 13.3 0.5 3.8 8.1 0.0 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L27A PF00828.19 OEU14530.1 - 3.2e-31 108.6 0.3 4.3e-31 108.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3439 PF11921.8 OEU14531.1 - 0.013 15.4 5.2 0.021 14.8 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF5506 PF17611.2 OEU14531.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5506) PLDc_2 PF13091.6 OEU14532.1 - 8.4e-10 38.6 0.1 3.6e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OEU14532.1 - 5.2e-05 23.2 5.0 0.18 12.0 1.0 3.0 2 0 0 2 2 2 2 Phospholipase D Active site motif IBR PF01485.21 OEU14533.1 - 6.9e-16 58.2 38.6 6.1e-10 39.2 10.0 4.9 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain Ank_5 PF13857.6 OEU14533.1 - 6.6e-12 45.4 4.1 1.4e-05 25.2 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU14533.1 - 4.3e-11 43.3 3.7 6.5e-06 26.6 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU14533.1 - 2.7e-10 40.6 0.1 0.00051 20.5 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU14533.1 - 1.4e-07 31.3 1.1 0.036 14.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OEU14533.1 - 5.8e-06 26.5 0.1 0.094 13.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 OEU14533.1 - 0.01 15.7 3.8 0.01 15.7 3.8 4.3 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Fe_dep_repr_C PF02742.15 OEU14533.1 - 0.034 14.2 0.1 0.17 12.0 0.1 2.2 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain zf-C3HC4 PF00097.25 OEU14533.1 - 0.38 10.7 37.2 0.013 15.3 8.0 5.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.19 OEU14533.1 - 0.51 11.0 3.9 2.7 8.6 3.9 2.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Bestrophin PF01062.21 OEU14535.1 - 5.7e-32 111.3 0.0 7.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GST_N_3 PF13417.6 OEU14536.1 - 4.1e-26 91.2 0.1 1e-14 54.7 0.1 2.1 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU14536.1 - 9.8e-14 51.4 0.0 5.9e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU14536.1 - 4e-05 23.9 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU14536.1 - 0.0002 21.5 0.0 0.0017 18.5 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin zf-MYND PF01753.18 OEU14537.1 - 2.8e-07 30.5 12.7 6e-07 29.5 12.7 1.6 1 0 0 1 1 1 1 MYND finger SR-25 PF10500.9 OEU14537.1 - 0.18 11.4 7.6 0.34 10.5 7.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec5 PF15469.6 OEU14538.1 - 4.1e-14 52.8 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 OEU14538.1 - 5.5e-07 28.6 0.6 1.1e-06 27.5 0.6 1.5 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.13 OEU14538.1 - 0.0037 15.9 0.2 0.0066 15.1 0.2 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF1517 PF07466.11 OEU14538.1 - 0.036 14.2 0.4 0.15 12.1 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DASH_Dad2 PF08654.10 OEU14538.1 - 0.43 11.0 2.7 0.95 9.9 0.0 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad2 ERCC4 PF02732.15 OEU14539.1 - 2.7e-17 63.4 1.1 7.3e-17 62.0 0.2 2.3 2 0 0 2 2 2 1 ERCC4 domain SUIM_assoc PF16619.5 OEU14539.1 - 0.042 13.9 12.8 0.68 10.0 3.6 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HHH_8 PF14716.6 OEU14539.1 - 0.063 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Med19 PF10278.9 OEU14539.1 - 4.3 7.2 12.3 0.54 10.2 3.8 2.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 TFB6 PF17110.5 OEU14539.1 - 8.9 6.0 7.1 10 5.8 0.8 2.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Robl_LC7 PF03259.17 OEU14540.1 - 7e-06 25.7 3.2 0.0018 18.0 1.1 2.4 3 0 0 3 3 3 2 Roadblock/LC7 domain DUF1635 PF07795.11 OEU14540.1 - 0.34 10.7 2.3 0.52 10.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) 2OG-FeII_Oxy_3 PF13640.6 OEU14541.1 - 4.7e-05 24.2 0.1 0.00034 21.5 0.0 2.3 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Gemini_AL1_M PF08283.11 OEU14541.1 - 0.061 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain DUF3724 PF12521.8 OEU14541.1 - 0.075 13.0 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Miga PF10265.9 OEU14541.1 - 0.51 9.3 3.3 0.68 8.8 3.3 1.1 1 0 0 1 1 1 0 Mitoguardin MFS_1 PF07690.16 OEU14543.1 - 3.5e-27 95.3 17.9 8.9e-27 93.9 18.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 OEU14543.1 - 0.24 11.0 1.4 16 5.1 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) NUDIX PF00293.28 OEU14544.1 - 6.3e-05 23.0 0.0 7.6e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Dehydrin PF00257.19 OEU14544.1 - 0.037 14.6 2.9 0.056 14.0 2.9 1.2 1 0 0 1 1 1 0 Dehydrin SWIRM-assoc_2 PF16496.5 OEU14546.1 - 0.056 12.3 9.9 0.11 11.4 9.9 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ribosomal_60s PF00428.19 OEU14546.1 - 0.55 10.8 14.7 1.1 9.9 0.7 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF4148 PF13663.6 OEU14546.1 - 3.3 8.0 6.3 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) adh_short_C2 PF13561.6 OEU14547.1 - 2.4e-40 138.6 0.3 7.9e-40 136.9 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU14547.1 - 7.3e-36 123.5 1.4 1e-35 123.0 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OEU14547.1 - 0.0015 18.0 0.0 0.0032 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 OEU14547.1 - 0.005 16.4 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 SLOG cluster4 family ADH_zinc_N PF00107.26 OEU14547.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 OEU14547.1 - 0.014 15.3 0.7 0.049 13.5 0.1 2.0 2 0 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.8 OEU14547.1 - 0.017 14.9 1.1 0.044 13.6 1.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 OEU14547.1 - 0.038 13.3 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 OEU14547.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF599 PF04654.12 OEU14549.1 - 2.7e-22 79.2 0.5 3.1e-22 79.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 PAE PF03283.13 OEU14550.1 - 9.3e-08 31.6 0.4 1.1e-07 31.3 0.4 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Ncstrn_small PF18266.1 OEU14550.1 - 0.041 13.9 1.1 0.067 13.2 1.1 1.5 1 1 0 1 1 1 0 Nicastrin small lobe Helicase_C PF00271.31 OEU14553.1 - 1.8e-22 79.8 0.0 3.7e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Thioredoxin_11 PF18078.1 OEU14553.1 - 0.057 13.5 1.3 0.17 12.0 1.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like SNTX domain BNIP2 PF12496.8 OEU14553.1 - 7 7.1 9.3 49 4.4 9.3 2.1 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TetR_C_19 PF17924.1 OEU14554.1 - 0.23 12.0 6.5 1.4 9.5 0.4 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Serglycin PF04360.12 OEU14555.1 - 0.033 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Serglycin 7tm_3 PF00003.22 OEU14556.1 - 1.2e-35 123.4 13.6 1.7e-35 122.8 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Ephrin_rec_like PF07699.13 OEU14556.1 - 0.00018 21.2 3.0 0.00018 21.2 3.0 2.0 2 0 0 2 2 2 1 Putative ephrin-receptor like Peripla_BP_6 PF13458.6 OEU14556.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Periplasmic binding protein DUF4818 PF16089.5 OEU14556.1 - 1.1 9.8 4.5 1.7 9.2 2.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4818) DUF898 PF05987.13 OEU14556.1 - 3.7 6.5 9.2 12 4.9 9.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Tricorn_C1 PF14684.6 OEU14558.1 - 2.9e-25 88.1 0.2 6e-25 87.1 0.2 1.6 1 0 0 1 1 1 1 Tricorn protease C1 domain Peptidase_S41 PF03572.18 OEU14558.1 - 7.3e-18 64.7 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 OEU14558.1 - 1.3e-08 34.6 2.5 3.5e-08 33.2 0.5 2.6 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 OEU14558.1 - 7.9e-05 22.6 0.0 0.00042 20.2 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 OEU14558.1 - 0.0028 17.9 0.3 0.0093 16.3 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OEU14558.1 - 0.0037 17.6 0.0 0.0098 16.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain CIDE-N PF02017.15 OEU14559.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.5 1 1 1 2 2 2 0 CIDE-N domain Aa_trans PF01490.18 OEU14561.1 - 4.1e-58 197.0 18.0 4.8e-58 196.8 18.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3671 PF12420.8 OEU14561.1 - 0.0094 16.0 3.2 2.2 8.4 1.6 3.0 2 1 0 2 2 2 2 Protein of unknown function MWFE PF15879.5 OEU14561.1 - 2.1 8.6 7.1 4.3 7.6 0.9 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit SNF2_N PF00176.23 OEU14563.1 - 1.8e-72 244.0 0.2 1.8e-72 244.0 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 OEU14563.1 - 1.2e-24 86.5 1.0 4.5e-24 84.7 1.0 2.1 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 OEU14563.1 - 1.5e-19 70.4 0.0 9.1e-19 67.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU14563.1 - 2e-10 40.9 1.2 1e-09 38.7 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 OEU14563.1 - 8.9e-10 39.0 1.5 7e-09 36.2 1.5 2.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 OEU14563.1 - 5.7e-09 36.3 1.3 5.7e-09 36.3 1.3 4.1 5 0 0 5 5 5 1 HMG (high mobility group) box HDA2-3 PF11496.8 OEU14563.1 - 2.6e-06 26.8 0.2 9.3e-06 25.0 0.2 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU14563.1 - 0.00033 20.5 0.0 0.0026 17.6 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_M3 PF01432.20 OEU14564.1 - 5.8e-25 88.5 0.0 1.1e-23 84.2 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M3 Peptidase_M2 PF01401.18 OEU14564.1 - 4e-07 29.1 2.5 6.9e-07 28.3 2.5 1.3 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M32 PF02074.15 OEU14564.1 - 0.0013 17.6 0.0 1.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Carboxypeptidase Taq (M32) metallopeptidase LRR_8 PF13855.6 OEU14565.1 - 2.7e-23 81.5 27.8 3.5e-07 29.9 1.0 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OEU14565.1 - 1.7e-18 66.4 24.2 6.9e-05 23.1 1.3 5.1 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14565.1 - 0.00046 20.4 29.0 4.7 8.2 0.3 7.5 7 1 1 8 8 8 5 Leucine Rich Repeat LRR_9 PF14580.6 OEU14565.1 - 0.017 14.6 4.8 0.59 9.6 1.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeat Chaperone_III PF07824.12 OEU14565.1 - 0.028 14.6 0.4 0.062 13.5 0.1 1.8 2 1 0 2 2 2 0 Type III secretion chaperone domain DUF5565 PF17720.1 OEU14565.1 - 0.057 12.3 0.4 6.6 5.5 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5565) Voldacs PF03517.13 OEU14566.1 - 0.057 13.5 3.7 0.1 12.7 0.3 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling GPAT_N PF14829.6 OEU14567.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Methyltransf_32 PF13679.6 OEU14568.1 - 0.0061 16.6 10.4 0.0077 16.2 0.1 4.2 4 1 0 4 4 4 1 Methyltransferase domain TRM13 PF05206.14 OEU14568.1 - 0.039 13.5 2.1 0.14 11.7 2.0 2.0 1 1 0 1 1 1 0 Methyltransferase TRM13 AAA PF00004.29 OEU14569.1 - 9.4e-39 132.9 0.0 1.1e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OEU14569.1 - 4.8e-05 23.1 0.1 0.00017 21.4 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OEU14569.1 - 0.00011 22.3 0.0 0.00038 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OEU14569.1 - 0.00036 20.8 0.1 0.0031 17.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU14569.1 - 0.00054 20.5 0.0 0.00073 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU14569.1 - 0.0009 19.7 0.2 0.0057 17.1 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 OEU14569.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 OEU14569.1 - 0.0019 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OEU14569.1 - 0.0033 17.6 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU14569.1 - 0.0038 17.2 0.0 0.016 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU14569.1 - 0.0053 16.2 0.3 0.0098 15.3 0.1 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OEU14569.1 - 0.013 15.2 0.2 0.021 14.6 0.2 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 OEU14569.1 - 0.019 15.4 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU14569.1 - 0.071 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 OEU14569.1 - 0.1 12.3 0.0 0.42 10.3 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 OEU14569.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU14569.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OEU14569.1 - 0.21 11.3 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 OEU14569.1 - 0.25 11.5 0.0 0.32 11.1 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family zf-C3HC4 PF00097.25 OEU14571.1 - 5.3e-08 32.6 13.7 2.4e-07 30.5 13.7 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU14571.1 - 2e-07 30.7 14.1 6e-07 29.2 14.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU14571.1 - 3.1e-06 27.4 13.7 3.1e-06 27.4 13.7 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU14571.1 - 5.4e-06 26.2 9.3 5.4e-06 26.2 9.3 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU14571.1 - 2e-05 24.3 11.8 7.3e-05 22.5 11.8 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OEU14571.1 - 5.9e-05 22.9 7.2 0.00017 21.4 7.2 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OEU14571.1 - 7.6e-05 22.6 11.0 7.6e-05 22.6 11.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 OEU14571.1 - 0.0012 19.0 8.8 0.0012 19.0 8.8 3.0 3 1 0 3 3 3 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 OEU14571.1 - 0.0017 18.4 13.3 0.0017 18.4 13.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OEU14571.1 - 0.041 14.2 10.8 0.041 14.2 10.8 3.5 4 1 0 4 4 4 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OEU14571.1 - 0.069 13.3 17.0 0.047 13.9 12.0 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING WASH-7_C PF14746.6 OEU14571.1 - 0.069 12.8 1.9 0.13 11.9 1.9 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal ZapB PF06005.12 OEU14571.1 - 1.3 9.5 19.5 8.4 6.9 19.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF1043 PF06295.12 OEU14571.1 - 1.4 8.9 5.9 1.1 9.3 4.2 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1043) DUF5320 PF17253.2 OEU14571.1 - 1.7 9.7 3.5 0.58 11.3 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) ADIP PF11559.8 OEU14571.1 - 2.1 8.4 14.4 3 7.9 14.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3552 PF12072.8 OEU14571.1 - 2.7 7.4 13.7 4.1 6.8 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fer2 PF00111.27 OEU14572.1 - 0.00012 21.9 0.3 0.00028 20.8 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DEAD PF00270.29 OEU14573.1 - 3.7e-41 140.8 0.0 1.3e-40 139.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU14573.1 - 1.7e-19 70.2 0.1 3.2e-18 66.1 0.1 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU14573.1 - 1e-06 28.9 0.0 1.1e-05 25.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OEU14573.1 - 5e-06 26.0 0.2 1.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Arginosuc_synth PF00764.19 OEU14573.1 - 0.02 14.2 0.1 4.1 6.6 0.1 2.4 2 1 0 2 2 2 0 Arginosuccinate synthase AAA_22 PF13401.6 OEU14573.1 - 0.021 15.1 0.2 0.086 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain HEPN_AbiU2 PF18734.1 OEU14574.1 - 0.086 12.3 2.5 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 AbiU2 PH_4 PF15404.6 OEU14574.1 - 0.31 10.8 3.4 2.1 8.1 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DNA_pol_phi PF04931.13 OEU14574.1 - 1.4 6.9 39.2 0.2 9.7 20.0 2.1 2 0 0 2 2 2 0 DNA polymerase phi CDC45 PF02724.14 OEU14574.1 - 2.1 6.5 18.5 0.018 13.3 4.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Mpp10 PF04006.12 OEU14574.1 - 3.7 5.9 23.6 0.19 10.1 9.2 2.1 2 0 0 2 2 2 0 Mpp10 protein RPA43_OB PF17875.1 OEU14574.1 - 3.8 8.2 9.6 0.97 10.1 1.7 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Nop14 PF04147.12 OEU14574.1 - 5.3 5.1 25.6 0.19 9.9 10.1 2.1 2 0 0 2 2 2 0 Nop14-like family Astro_capsid_p PF12226.8 OEU14574.1 - 7.5 5.6 25.8 1 8.5 7.6 2.4 2 0 0 2 2 2 0 Turkey astrovirus capsid protein TPR_2 PF07719.17 OEU14575.1 - 0.0013 18.6 0.3 0.017 15.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU14575.1 - 0.12 13.0 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 OEU14577.1 - 1.3e-40 139.5 0.0 1e-38 133.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14577.1 - 2.9e-08 33.3 0.0 8.7e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU14577.1 - 0.00013 20.9 0.0 0.00025 19.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OEU14577.1 - 0.048 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OEU14577.1 - 0.14 12.1 0.6 2.1 8.2 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family GIY-YIG PF01541.24 OEU14578.1 - 2.3e-11 43.8 0.1 2.3e-11 43.8 0.1 2.5 2 0 0 2 2 2 1 GIY-YIG catalytic domain Ion_trans_2 PF07885.16 OEU14579.1 - 4.4e-27 93.8 18.7 1.3e-14 53.9 9.5 2.6 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.31 OEU14579.1 - 9.6e-08 31.5 7.8 0.00013 21.3 2.9 2.3 1 1 1 2 2 2 2 Ion transport protein DUF2254 PF10011.9 OEU14579.1 - 3.6e-05 22.8 0.1 0.022 13.6 0.0 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2254) Lig_chan PF00060.26 OEU14579.1 - 0.00017 21.5 0.1 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 Ligand-gated ion channel 7tm_7 PF08395.12 OEU14579.1 - 0.00041 19.7 0.3 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 7tm Chemosensory receptor IRK PF01007.20 OEU14579.1 - 0.041 13.7 4.5 0.22 11.3 1.0 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain CCDC106 PF15794.5 OEU14581.1 - 0.51 10.0 4.4 0.54 9.9 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SRC-1 PF08832.10 OEU14581.1 - 2.1 9.4 5.9 1.8 9.7 1.1 2.5 2 0 0 2 2 2 0 Steroid receptor coactivator DUF2196 PF09962.9 OEU14582.1 - 3.1e-21 75.1 2.0 5.2e-21 74.4 2.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-RanBP PF00641.18 OEU14582.1 - 0.00011 21.5 4.5 0.00018 20.7 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Acetyltransf_9 PF13527.7 OEU14583.1 - 3.2e-09 36.9 0.0 4.5e-08 33.2 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU14583.1 - 0.0011 18.9 0.0 0.0039 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU14583.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 OEU14583.1 - 0.0019 18.4 0.0 0.0073 16.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family BUD22 PF09073.10 OEU14583.1 - 0.83 8.9 18.5 0.17 11.2 12.6 2.2 2 0 0 2 2 2 0 BUD22 SUIM_assoc PF16619.5 OEU14583.1 - 1 9.5 8.5 1.1 9.4 1.0 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UAA PF08449.11 OEU14584.1 - 2.1e-38 132.3 8.9 2.4e-38 132.1 8.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU14584.1 - 2.3e-05 24.6 9.4 2.3e-05 24.6 9.4 2.6 2 1 1 3 3 3 1 EamA-like transporter family TPT PF03151.16 OEU14584.1 - 0.016 14.6 6.9 0.024 14.0 6.9 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family RTP1_C1 PF10363.9 OEU14585.1 - 1.2e-17 64.0 0.0 1.1e-16 61.0 0.0 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF775 PF05603.12 OEU14585.1 - 0.28 10.7 2.6 4 6.9 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) zf-Nse PF11789.8 OEU14587.1 - 1.8e-10 40.5 0.2 3.9e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 OEU14587.1 - 8.4e-09 35.5 0.4 1.7e-06 28.1 0.1 2.5 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.6 OEU14587.1 - 1.2e-05 25.2 0.4 3e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU14587.1 - 0.00076 19.8 0.2 0.0017 18.6 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU14587.1 - 0.00077 19.7 0.2 0.0028 17.9 0.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OEU14587.1 - 0.0015 18.6 0.1 0.0035 17.5 0.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OEU14587.1 - 0.0035 17.1 0.2 0.008 16.0 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU14587.1 - 0.0052 16.6 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU14587.1 - 0.0088 16.1 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-NOSIP PF15906.5 OEU14587.1 - 0.0098 16.0 0.0 0.033 14.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein BUD22 PF09073.10 OEU14587.1 - 0.018 14.4 14.5 0.16 11.3 12.1 2.1 2 0 0 2 2 2 0 BUD22 Herpes_US9 PF06072.11 OEU14587.1 - 0.099 12.5 1.7 0.27 11.1 1.7 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SNARE PF05739.19 OEU14587.1 - 0.12 12.4 2.1 0.31 11.1 2.1 1.7 1 0 0 1 1 1 0 SNARE domain Pox_EPC_I2-L1 PF12575.8 OEU14587.1 - 1 9.7 2.8 3.7 7.9 0.6 2.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Auxin_canalis PF05703.11 OEU14588.1 - 0.32 10.9 11.9 0.68 9.8 0.9 2.2 2 0 0 2 2 2 0 Auxin canalisation FAM60A PF15396.6 OEU14588.1 - 5.1 7.1 9.2 2.1 8.3 3.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Kinesin PF00225.23 OEU14589.1 - 1.2e-56 192.1 4.5 3.8e-56 190.4 4.5 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU14589.1 - 4.6e-28 98.0 0.0 8e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AvrPphF-ORF-2 PF09143.10 OEU14589.1 - 0.0033 17.4 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 AvrPphF-ORF-2 Thioesterase PF00975.20 OEU14589.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Cons_hypoth95 PF03602.15 OEU14590.1 - 0.062 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 YjbH PF06082.11 OEU14590.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH TFIIS_C PF01096.18 OEU14591.1 - 4.1e-17 61.7 4.0 6.8e-17 61.0 4.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 OEU14591.1 - 8e-15 55.3 2.9 8e-15 55.3 2.9 2.2 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 OEU14591.1 - 5.8e-09 35.8 0.3 1.7e-08 34.3 0.3 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 OEU14591.1 - 0.01 15.8 0.7 0.036 14.0 0.7 2.0 1 0 0 1 1 1 0 DNL zinc finger Chloroa_b-bind PF00504.21 OEU14592.1 - 7.8e-28 98.0 0.0 1.6e-27 97.0 0.0 1.5 1 1 0 1 1 1 1 Chlorophyll A-B binding protein PMSR PF01625.21 OEU14593.1 - 5.4e-27 94.9 1.7 7.5e-27 94.4 1.7 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Exo_endo_phos PF03372.23 OEU14594.1 - 1.4e-11 44.4 0.1 3.1e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Arf PF00025.21 OEU14595.1 - 9.5e-45 152.2 0.1 1e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OEU14595.1 - 1.3e-14 54.4 0.0 2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OEU14595.1 - 6e-14 51.9 0.0 8.1e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OEU14595.1 - 7.7e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OEU14595.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OEU14595.1 - 7.4e-08 32.2 0.1 1.9e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OEU14595.1 - 2.9e-07 30.1 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OEU14595.1 - 4.2e-06 26.2 0.5 0.00029 20.1 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 OEU14595.1 - 0.00075 19.1 0.5 0.036 13.6 0.5 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 OEU14595.1 - 0.0036 16.9 0.1 0.37 10.4 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OEU14595.1 - 0.032 14.3 0.1 7 6.7 0.1 2.2 1 1 0 2 2 2 0 Dynamin family 6PF2K PF01591.18 OEU14595.1 - 0.038 13.3 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1_Xtn PF16897.5 OEU14595.1 - 0.045 13.8 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MobB PF03205.14 OEU14595.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B preATP-grasp_3 PF18301.1 OEU14595.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain PduV-EutP PF10662.9 OEU14595.1 - 0.11 12.2 0.1 0.82 9.4 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OEU14595.1 - 0.16 12.2 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OEU14595.1 - 0.18 11.4 0.1 0.24 10.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain Bac_globin PF01152.21 OEU14597.1 - 3.1e-23 82.2 0.0 4.6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial-like globin DnaJ PF00226.31 OEU14598.1 - 3.5e-21 75.1 1.4 9.2e-21 73.7 1.4 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 OEU14598.1 - 1.3e-13 50.8 0.7 3.6e-13 49.4 0.3 2.0 1 1 1 2 2 2 1 X-domain of DnaJ-containing RPT PF13446.6 OEU14598.1 - 0.077 12.9 0.4 8.5 6.4 0.0 3.4 3 0 0 3 3 3 0 A repeated domain in UCH-protein Myb_DNA-binding PF00249.31 OEU14599.1 - 4e-15 55.7 5.2 3.4e-08 33.5 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU14599.1 - 6.9e-10 39.0 6.9 0.00011 22.3 0.4 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU14599.1 - 4.5e-06 26.5 0.8 1.1e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OEU14599.1 - 0.0044 17.1 0.0 1.4 9.0 0.0 2.8 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Tna_leader PF08053.11 OEU14599.1 - 0.069 13.1 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Afaf PF15339.6 OEU14599.1 - 0.091 12.5 0.6 0.12 12.1 0.6 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor TENA_THI-4 PF03070.16 OEU14601.1 - 0.057 13.2 2.0 0.21 11.4 0.2 2.4 3 0 0 3 3 3 0 TENA/THI-4/PQQC family Taxilin PF09728.9 OEU14601.1 - 0.17 11.0 11.9 0.33 10.1 11.9 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.12 OEU14601.1 - 0.25 11.4 10.5 0.085 12.9 3.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_holin_7_1 PF16081.5 OEU14601.1 - 1.9 8.6 4.3 1.7 8.8 0.2 2.6 1 1 2 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Gp-FAR-1 PF05823.12 OEU14601.1 - 2.7 8.3 8.2 5.7 7.3 2.4 2.6 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Actin PF00022.19 OEU14602.1 - 2.8e-70 237.0 0.0 3.2e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OEU14602.1 - 0.037 12.8 0.0 1.3 7.7 0.0 2.5 2 1 1 3 3 3 0 MreB/Mbl protein AIM3 PF17096.5 OEU14602.1 - 0.25 12.3 5.2 2.3 9.2 0.5 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DTC PF18102.1 OEU14603.1 - 5.4e-40 136.6 0.8 1.4e-39 135.3 0.1 2.0 2 0 0 2 2 2 1 Deltex C-terminal domain zf-RING_2 PF13639.6 OEU14603.1 - 8.2e-09 35.7 10.1 2.2e-08 34.3 10.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU14603.1 - 2.9e-06 27.0 9.5 7.8e-06 25.6 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU14603.1 - 3.5e-06 27.2 5.4 1.4e-05 25.3 5.4 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OEU14603.1 - 1.4e-05 24.8 8.3 3e-05 23.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU14603.1 - 2.8e-05 24.1 4.2 2.8e-05 24.1 4.2 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU14603.1 - 0.00018 21.4 8.7 0.00041 20.2 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain PARP PF00644.20 OEU14603.1 - 0.00086 18.9 0.4 0.00086 18.9 0.4 2.7 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain Prok-RING_4 PF14447.6 OEU14603.1 - 0.0014 18.5 10.3 0.044 13.7 10.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OEU14603.1 - 0.0022 17.7 3.6 0.0022 17.7 3.6 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OEU14603.1 - 0.0038 17.3 2.6 0.01 15.9 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OEU14603.1 - 0.0092 15.8 9.5 0.024 14.5 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OEU14603.1 - 0.022 14.7 4.2 0.059 13.3 4.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DarT PF14487.6 OEU14603.1 - 0.026 14.4 0.1 0.08 12.8 0.1 1.9 1 0 0 1 1 1 0 ssDNA thymidine ADP-ribosyltransferase, DarT zf-C3HC4_5 PF17121.5 OEU14603.1 - 0.36 10.8 5.7 10 6.1 7.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 OEU14603.1 - 0.42 10.3 3.6 11 5.8 1.0 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-Nse PF11789.8 OEU14603.1 - 0.47 10.3 6.9 1.4 8.8 6.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 OEU14603.1 - 1.8 8.8 7.7 4.4 7.5 7.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_1 PF14446.6 OEU14603.1 - 3.2 7.7 10.0 7.6 6.6 4.1 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OEU14603.1 - 7.1 6.5 7.6 27 4.6 7.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ADIP PF11559.8 OEU14604.1 - 0.0018 18.4 12.4 0.0018 18.4 12.4 4.0 2 2 2 4 4 4 2 Afadin- and alpha -actinin-Binding TetR_C_13 PF16925.5 OEU14604.1 - 0.046 13.6 0.2 0.046 13.6 0.2 2.8 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain NPV_P10 PF05531.12 OEU14604.1 - 0.049 14.1 3.5 0.096 13.2 0.9 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 OEU14604.1 - 0.32 10.5 22.8 0.16 11.5 5.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3866 PF12982.7 OEU14604.1 - 0.76 8.8 3.3 2.3 7.3 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3866) Laminin_II PF06009.12 OEU14604.1 - 0.77 9.8 22.6 0.051 13.6 9.1 2.5 2 1 0 2 2 2 0 Laminin Domain II Golgin_A5 PF09787.9 OEU14604.1 - 1.5 8.2 39.6 1.8 8.0 13.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF948 PF06103.11 OEU14604.1 - 2.2 8.6 4.5 2 8.8 2.0 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Me-amine-dh_L PF02975.14 OEU14605.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain RVT_1 PF00078.27 OEU14607.1 - 4.8e-05 23.0 0.0 0.00026 20.6 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU14607.1 - 0.012 16.2 0.3 0.056 14.2 0.3 2.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 OEU14607.1 - 0.03 13.8 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Mei5_like PF17021.5 OEU14607.1 - 0.098 12.7 4.6 0.2 11.7 0.2 2.8 2 0 0 2 2 2 0 Putative double-strand recombination repair-like GRP PF07172.11 OEU14608.1 - 4.2 8.1 15.4 14 6.4 15.4 1.9 1 0 0 1 1 1 0 Glycine rich protein family TPR_12 PF13424.6 OEU14609.1 - 5.2e-21 74.7 5.0 1.1e-07 32.0 0.1 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 OEU14609.1 - 2.6e-15 56.3 0.0 2.4e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 OEU14609.1 - 3.3e-10 39.5 7.6 0.039 13.8 0.0 6.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU14609.1 - 2.6e-09 36.4 0.4 0.07 13.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU14609.1 - 5.2e-07 29.4 7.6 0.013 15.6 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat SNAP PF14938.6 OEU14609.1 - 5.2e-06 26.1 4.6 0.00034 20.1 0.2 3.7 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 OEU14609.1 - 0.0025 17.6 3.3 0.76 9.7 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU14609.1 - 0.0057 16.1 0.2 0.17 11.2 0.2 2.5 2 0 0 2 2 2 1 MalT-like TPR region DUF2333 PF10095.9 OEU14609.1 - 0.019 14.0 1.0 0.83 8.6 0.5 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2333) TPR_2 PF07719.17 OEU14609.1 - 0.1 12.8 6.7 88 3.6 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 OEU14609.1 - 0.11 12.8 2.8 9.6 6.7 0.0 4.4 4 0 0 4 4 4 0 PPR repeat RPN6_N PF18055.1 OEU14609.1 - 0.24 11.8 1.4 39 4.6 0.1 3.4 3 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain MIT PF04212.18 OEU14609.1 - 0.51 10.4 2.1 2.2 8.4 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF4061 PF13270.6 OEU14610.1 - 0.0075 16.6 4.2 0.0075 16.6 4.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) Nup88 PF10168.9 OEU14610.1 - 0.14 9.9 8.7 0.21 9.4 8.7 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF3122 PF11320.8 OEU14610.1 - 0.61 10.2 3.4 15 5.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3122) DUF2321 PF10083.9 OEU14610.1 - 5.7 6.5 7.0 0.56 9.8 1.9 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Linker_histone PF00538.19 OEU14611.1 - 1.8e-13 50.6 1.0 1.8e-13 50.6 1.0 2.7 1 1 0 2 2 2 1 linker histone H1 and H5 family SAPS PF04499.15 OEU14611.1 - 5.6 5.6 11.1 6.6 5.4 11.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2981 PF11200.8 OEU14611.1 - 6.1 6.5 12.0 7 6.3 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PCM1_C PF15717.5 OEU14611.1 - 6.9 5.2 15.0 8.4 4.9 15.0 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus RR_TM4-6 PF06459.12 OEU14611.1 - 7.6 6.3 22.7 10 5.8 22.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 OEU14611.1 - 9.8 5.1 16.8 12 4.8 16.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Glyco_transf_90 PF05686.12 OEU14613.1 - 6.4e-15 55.0 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 ABC_tran PF00005.27 OEU14615.1 - 2.4e-42 144.7 0.1 9.8e-21 74.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OEU14615.1 - 1.5e-18 67.7 0.4 7.3e-05 22.7 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU14615.1 - 1.6e-11 44.1 0.1 8.7e-07 28.6 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU14615.1 - 4.9e-07 30.3 0.2 0.027 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU14615.1 - 2e-06 27.4 0.0 0.039 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 OEU14615.1 - 2.7e-06 27.4 0.0 0.0045 16.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 OEU14615.1 - 2.4e-05 25.0 6.2 0.069 13.6 2.4 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OEU14615.1 - 2.5e-05 24.3 0.0 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 OEU14615.1 - 2.5e-05 24.7 0.0 0.19 12.2 0.0 3.2 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OEU14615.1 - 6.2e-05 23.2 0.0 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OEU14615.1 - 0.00012 22.1 0.0 0.0068 16.4 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 OEU14615.1 - 0.00013 21.8 0.0 0.39 10.4 0.0 3.0 4 0 0 4 4 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 OEU14615.1 - 0.00014 21.9 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OEU14615.1 - 0.00026 21.2 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran_Xtn PF12848.7 OEU14615.1 - 0.00027 20.9 5.1 0.00054 19.9 5.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OEU14615.1 - 0.00037 20.8 0.1 1.2 9.4 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OEU14615.1 - 0.00082 19.1 0.1 2.8 7.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 OEU14615.1 - 0.0012 19.3 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 OEU14615.1 - 0.0014 18.6 0.1 0.51 10.2 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 OEU14615.1 - 0.0018 18.3 0.1 3.3 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OEU14615.1 - 0.002 18.4 0.0 0.72 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OEU14615.1 - 0.0036 17.0 0.0 2 8.1 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 OEU14615.1 - 0.006 16.3 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OEU14615.1 - 0.013 15.0 0.0 1 8.9 0.0 2.9 4 0 0 4 4 4 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OEU14615.1 - 0.018 14.8 0.2 0.92 9.2 0.2 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OEU14615.1 - 0.022 13.9 0.0 3.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OEU14615.1 - 0.027 15.0 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OEU14615.1 - 0.035 13.3 0.1 7.3 5.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 OEU14615.1 - 0.041 13.6 0.0 17 5.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 OEU14615.1 - 0.093 12.8 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 OEU14615.1 - 0.17 11.4 1.0 7.3 6.1 0.0 3.3 4 1 1 5 5 5 0 AAA domain SbcCD_C PF13558.6 OEU14615.1 - 0.24 11.7 1.3 5.6 7.3 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Aph-1 PF06105.12 OEU14616.1 - 9e-29 100.5 7.2 7.6e-28 97.5 7.2 1.9 1 1 0 1 1 1 1 Aph-1 protein YhfC PF10086.9 OEU14616.1 - 0.068 12.5 0.7 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease Nab6_mRNP_bdg PF10567.9 OEU14616.1 - 0.15 11.5 0.9 0.21 11.0 0.9 1.1 1 0 0 1 1 1 0 RNA-recognition motif MscS_TM PF12794.7 OEU14616.1 - 0.33 9.8 0.0 0.33 9.8 0.0 2.4 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 SASA PF03629.18 OEU14617.1 - 3e-12 46.7 0.1 5.6e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SKA1 PF07160.12 OEU14618.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Ank_5 PF13857.6 OEU14619.1 - 6.8e-10 39.0 0.1 1.7e-05 25.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU14619.1 - 1.6e-08 35.0 0.0 0.0091 16.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU14619.1 - 1.8e-06 28.1 0.0 0.12 12.9 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Pkinase PF00069.25 OEU14619.1 - 9.6e-06 25.2 0.1 0.00015 21.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Ank_4 PF13637.6 OEU14619.1 - 8.8e-05 23.0 0.0 0.41 11.3 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU14619.1 - 0.00016 21.9 0.0 1 10.2 0.0 4.2 3 0 0 3 3 3 1 Ankyrin repeat AP2 PF00847.20 OEU14619.1 - 0.21 11.8 1.7 0.67 10.2 1.7 1.8 1 0 0 1 1 1 0 AP2 domain DUF1118 PF06549.12 OEU14620.1 - 9e-13 48.6 20.9 9.3e-07 29.2 7.5 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1118) Myb_DNA-binding PF00249.31 OEU14621.1 - 3.2e-26 91.2 8.4 2.1e-10 40.6 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU14621.1 - 9.1e-22 77.1 11.7 1.7e-10 41.0 0.1 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OEU14621.1 - 0.071 13.3 0.0 0.66 10.2 0.0 2.4 1 1 1 2 2 2 0 Rap1 Myb domain VP4_2 PF08935.10 OEU14621.1 - 0.16 12.6 0.1 0.25 12.0 0.1 1.3 1 0 0 1 1 1 0 Viral protein VP4 subunit MADF_DNA_bdg PF10545.9 OEU14621.1 - 0.6 10.5 4.2 13 6.2 0.1 3.1 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OEU14621.1 - 0.61 10.5 9.7 6.7 7.2 0.6 3.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ig_5 PF16681.5 OEU14622.1 - 0.054 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Peptidase_S10 PF00450.22 OEU14623.1 - 6.7e-80 269.5 0.1 1.4e-79 268.5 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Tannase PF07519.11 OEU14623.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase His_Phos_1 PF00300.22 OEU14624.1 - 3.2e-23 82.4 0.3 1.4e-21 77.1 0.3 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OEU14624.1 - 0.035 13.4 2.1 0.079 12.3 2.1 1.8 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Clathrin_lg_ch PF01086.17 OEU14624.1 - 0.078 13.0 0.6 0.078 13.0 0.6 1.7 2 0 0 2 2 2 0 Clathrin light chain FGGY_C PF02782.16 OEU14625.1 - 9.8e-61 204.9 0.4 1.1e-59 201.6 0.2 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OEU14625.1 - 3.7e-57 193.7 0.2 8.6e-57 192.5 0.2 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hydrolase_6 PF13344.6 OEU14626.1 - 1.1e-16 60.8 0.0 2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU14626.1 - 1.6e-10 40.9 0.0 3.6e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OEU14626.1 - 1.8e-08 34.7 0.1 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU14626.1 - 0.00076 19.8 0.0 0.0041 17.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OEU14626.1 - 0.02 14.5 1.9 0.76 9.4 0.3 2.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase 4_1_CTD PF05902.13 OEU14628.1 - 0.0053 16.8 3.8 0.035 14.2 3.8 2.5 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) Mis12 PF05859.12 OEU14629.1 - 0.0085 16.2 0.0 0.32 11.1 0.1 2.4 1 1 1 2 2 2 1 Mis12 protein DUF2229 PF09989.9 OEU14629.1 - 0.086 12.5 4.6 0.11 12.1 1.8 2.2 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) OATP PF03137.20 OEU14629.1 - 0.11 10.8 0.1 0.11 10.8 0.1 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Apolipoprotein PF01442.18 OEU14629.1 - 0.13 12.1 9.0 0.46 10.3 8.8 1.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.10 OEU14629.1 - 0.43 10.9 10.6 2.5 8.4 5.1 3.1 1 1 0 2 2 2 0 Phasin protein DUF883 PF05957.13 OEU14629.1 - 0.86 10.2 11.5 26 5.5 6.3 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 OEU14629.1 - 0.88 10.2 16.3 6.5 7.4 0.3 3.6 2 1 1 3 3 3 0 YtxH-like protein Perilipin PF03036.16 OEU14629.1 - 3.2 6.7 19.4 0.15 11.1 2.4 2.3 1 1 1 2 2 2 0 Perilipin family Prominin PF05478.11 OEU14629.1 - 3.4 5.5 11.5 5.8 4.7 10.6 1.6 1 1 0 1 1 1 0 Prominin HSF_DNA-bind PF00447.17 OEU14630.1 - 1.3e-35 121.8 5.0 5.4e-11 43.0 0.0 3.8 3 0 0 3 3 3 3 HSF-type DNA-binding Peripla_BP_2 PF01497.18 OEU14633.1 - 2.4e-10 40.4 0.0 1.5e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Periplasmic binding protein E3_UbLigase_R4 PF13764.6 OEU14633.1 - 0.0062 14.8 0.3 0.0083 14.3 0.3 1.1 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DeoRC PF00455.22 OEU14633.1 - 0.02 14.8 0.1 4.1 7.3 0.0 2.8 3 0 0 3 3 3 0 DeoR C terminal sensor domain RmuC PF02646.16 OEU14633.1 - 0.022 13.9 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 RmuC family DUF4242 PF14026.6 OEU14633.1 - 0.19 11.9 1.2 17 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4242) Herpes_gE PF02480.16 OEU14634.1 - 0.0036 16.1 0.9 0.0047 15.7 0.9 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E NTF2 PF02136.20 OEU14635.1 - 1.3e-10 41.9 0.0 4e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OEU14635.1 - 3.3e-06 26.8 0.2 2.4e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1517 PF07466.11 OEU14638.1 - 2.3e-41 142.0 1.8 2.5e-41 141.8 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) SR-25 PF10500.9 OEU14640.1 - 0.0087 15.7 21.1 0.053 13.1 8.9 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Rpr2 PF04032.16 OEU14640.1 - 0.09 13.1 5.1 0.11 12.8 2.3 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pribosyltran_N PF13793.6 OEU14642.1 - 1.4e-36 124.9 0.0 3.2e-34 117.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OEU14642.1 - 8.5e-13 48.7 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OEU14642.1 - 4.3e-11 42.6 0.0 6.1e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OEU14642.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF2633 PF11119.8 OEU14643.1 - 1.8 8.5 10.8 0.17 11.8 3.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) OrfB_IS605 PF01385.19 OEU14643.1 - 2.8 8.2 7.6 19 5.5 0.2 3.4 3 0 0 3 3 3 0 Probable transposase PT PF04886.12 OEU14644.1 - 1.2e-11 43.9 36.1 2e-06 27.2 15.0 2.6 1 1 1 2 2 2 2 PT repeat Glycoprotein_G PF00802.19 OEU14644.1 - 0.97 8.7 14.3 1.1 8.6 14.3 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF3439 PF11921.8 OEU14645.1 - 0.069 13.1 7.4 0.79 9.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Thioredoxin PF00085.20 OEU14648.1 - 3.9e-24 84.6 0.1 6.5e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OEU14648.1 - 3.3e-06 26.7 0.1 3.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OEU14648.1 - 1.1e-05 25.7 0.1 2.9e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OEU14648.1 - 1.5e-05 24.8 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OEU14648.1 - 8.5e-05 22.5 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU14648.1 - 0.00025 20.8 0.3 0.00034 20.3 0.3 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 OEU14648.1 - 0.00057 20.3 0.5 0.0025 18.2 0.3 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OEU14648.1 - 0.0033 17.6 0.1 0.0064 16.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 OEU14648.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 OEU14648.1 - 0.066 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Nup84_Nup100 PF04121.13 OEU14650.1 - 7.3e-27 93.8 2.2 8.1e-27 93.7 2.2 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 FA_hydroxylase PF04116.13 OEU14651.1 - 4.5e-11 43.2 22.4 5.1e-11 43.1 22.4 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily CENP-B_dimeris PF09026.10 OEU14652.1 - 0.99 9.8 4.9 1.9 8.9 4.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RasGEF_N PF00618.20 OEU14655.1 - 3.8 7.8 8.6 0.69 10.2 0.1 3.3 4 0 0 4 4 4 0 RasGEF N-terminal motif DKCLD PF08068.12 OEU14656.1 - 2.2e-32 110.9 2.2 8.4e-31 105.8 0.8 2.6 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 OEU14656.1 - 2.5e-22 79.8 0.2 5.7e-19 69.0 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OEU14656.1 - 4e-20 71.7 1.5 8e-20 70.8 1.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OEU14656.1 - 3.8e-19 68.4 2.3 9.3e-19 67.2 2.3 1.7 1 0 0 1 1 1 1 PUA domain VIR_N PF15912.5 OEU14656.1 - 1.7 8.2 7.2 2.9 7.4 7.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CCDC106 PF15794.5 OEU14656.1 - 9.9 5.8 17.3 21 4.8 17.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Hydrolase_4 PF12146.8 OEU14657.1 - 4.5e-07 29.4 0.0 5.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU14657.1 - 1.7e-06 27.9 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 OEU14657.1 - 0.00091 19.2 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 OEU14657.1 - 0.0043 16.9 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.16 OEU14657.1 - 0.1 12.4 0.0 3.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 OEU14657.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TAXi_N PF14543.6 OEU14658.1 - 8.6e-16 58.7 6.4 2.5e-15 57.2 6.4 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 OEU14658.1 - 3.5e-11 43.1 0.4 0.0003 20.3 0.0 3.5 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 OEU14658.1 - 0.011 15.5 0.0 1.7 8.4 0.0 2.6 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal TAXi_N PF14543.6 OEU14659.1 - 1e-19 71.5 3.7 1.8e-19 70.6 3.7 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 OEU14659.1 - 1.8e-13 50.6 1.4 1.5e-05 24.6 0.1 3.2 1 1 0 2 2 2 2 Eukaryotic aspartyl protease DDE_Tnp_1_6 PF13751.6 OEU14659.1 - 0.14 12.4 5.8 0.36 11.1 5.8 1.7 1 0 0 1 1 1 0 Transposase DDE domain SPT6_acidic PF14632.6 OEU14659.1 - 0.16 12.5 3.9 0.37 11.4 3.9 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 RseC_MucC PF04246.12 OEU14659.1 - 0.5 10.3 4.8 1.6 8.7 4.8 1.8 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC PTH2 PF01981.16 OEU14660.1 - 6.8e-44 148.9 0.1 7.5e-44 148.8 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPP_enzyme_C PF02775.21 OEU14660.1 - 0.0055 16.5 0.0 0.0065 16.3 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HTH_ParB PF17762.1 OEU14660.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 HTH domain found in ParB protein Acetyltransf_1 PF00583.25 OEU14661.1 - 2.8e-15 56.6 0.0 3.3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU14661.1 - 2.7e-11 43.5 0.0 3.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU14661.1 - 4.5e-11 42.6 0.1 6.1e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OEU14661.1 - 4.1e-10 39.9 0.0 5.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU14661.1 - 5.9e-06 26.4 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU14661.1 - 0.00039 20.5 0.1 0.00073 19.6 0.1 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 OEU14661.1 - 0.00048 19.9 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 OEU14661.1 - 0.004 17.8 0.0 0.0047 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OEU14661.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 OEU14661.1 - 0.056 13.7 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_13 PF13880.6 OEU14661.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RecX PF02631.16 OEU14661.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 RecX family zf-RING_2 PF13639.6 OEU14662.1 - 1.2e-12 47.9 10.1 2.1e-12 47.1 10.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU14662.1 - 1.9e-09 37.1 8.2 5.5e-09 35.6 8.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU14662.1 - 9.6e-09 35.0 9.2 1.6e-08 34.3 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU14662.1 - 3.6e-07 29.9 8.5 6.5e-07 29.1 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU14662.1 - 1.5e-06 28.4 9.3 3.6e-06 27.2 9.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 OEU14662.1 - 2.2e-05 24.7 7.7 3.7e-05 23.9 7.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_UBOX PF13445.6 OEU14662.1 - 3e-05 24.0 6.1 3.3e-05 23.8 4.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU14662.1 - 4.2e-05 23.4 7.7 7.1e-05 22.7 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 OEU14662.1 - 0.0024 18.0 1.6 0.0046 17.1 1.6 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.6 OEU14662.1 - 0.0052 16.6 5.9 0.0088 15.9 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU14662.1 - 0.0062 16.6 3.3 0.016 15.2 3.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Dehydrin PF00257.19 OEU14662.1 - 0.0073 16.9 1.1 1.2 9.6 0.7 2.8 3 0 0 3 3 3 1 Dehydrin zf-HC5HC2H PF13771.6 OEU14662.1 - 0.011 16.0 3.4 0.023 14.9 3.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 OEU14662.1 - 0.11 12.1 8.7 0.24 11.1 8.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OEU14662.1 - 0.15 12.2 5.5 0.34 11.1 5.5 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 OEU14662.1 - 0.18 11.6 7.8 0.13 12.1 5.9 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OEU14662.1 - 0.21 11.4 6.7 0.44 10.4 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OEU14662.1 - 0.32 11.2 7.5 0.61 10.3 7.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OEU14662.1 - 9.3 6.3 7.9 31 4.6 3.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 LUC7 PF03194.15 OEU14663.1 - 3.7e-28 98.9 17.8 5.3e-26 91.8 14.3 2.9 2 1 0 2 2 2 2 LUC7 N_terminus ALMT PF11744.8 OEU14663.1 - 0.13 11.0 7.6 0.18 10.6 7.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0228 PF05727.11 OEU14663.1 - 0.32 10.8 8.1 0.1 12.4 4.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0228) DDHD PF02862.17 OEU14663.1 - 0.37 10.9 2.7 0.52 10.4 2.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 OEU14663.1 - 2.5 7.4 12.9 0.6 9.4 9.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) dsRBD2 PF17842.1 OEU14663.1 - 5.2 7.3 7.3 1.5 9.0 3.6 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 GSDH PF07995.11 OEU14664.1 - 1.1e-38 133.4 0.1 1.1e-35 123.5 0.1 2.2 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU14664.1 - 6.1e-13 48.4 0.4 1.4e-12 47.3 0.4 1.6 1 0 0 1 1 1 1 PKD domain DUF2207 PF09972.9 OEU14664.1 - 0.011 14.5 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 OEU14664.1 - 0.018 15.0 1.6 0.046 13.6 0.1 2.6 3 0 0 3 3 3 0 TMEM154 protein family Big_7 PF17957.1 OEU14664.1 - 0.023 15.5 0.1 0.14 13.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig domain UPF0506 PF11703.8 OEU14664.1 - 0.025 14.9 5.9 0.052 13.9 5.9 1.5 1 0 0 1 1 1 0 UPF0506 Herpes_gE PF02480.16 OEU14664.1 - 0.033 12.9 0.8 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E PKD_3 PF16820.5 OEU14664.1 - 0.05 13.4 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 PKD-like domain ABG_transport PF03806.13 OEU14664.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Toxin_29 PF08116.11 OEU14664.1 - 1.8 8.6 7.0 3.8 7.6 7.0 1.5 1 0 0 1 1 1 0 PhTx neurotoxin family F-box-like PF12937.7 OEU14666.1 - 0.036 14.0 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 OEU14667.1 - 2.9e-27 94.2 25.4 1.4e-07 31.2 5.6 5.4 3 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OEU14667.1 - 5.2e-11 42.6 31.9 0.024 15.1 0.5 7.2 4 2 5 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14667.1 - 0.00034 20.8 30.4 0.16 12.6 0.2 10.4 12 1 0 12 12 12 2 Leucine Rich Repeat DUF3338 PF11819.8 OEU14667.1 - 0.0065 16.5 0.0 0.8 9.7 0.0 3.7 4 2 1 5 5 5 1 Domain of unknown function (DUF3338) LRRNT_2 PF08263.12 OEU14667.1 - 0.053 13.8 2.1 0.14 12.5 2.1 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 OEU14667.1 - 6.2 7.1 27.0 4.1 7.7 1.1 8.0 11 0 0 11 11 11 0 Leucine Rich repeat COPI_assoc PF08507.10 OEU14668.1 - 2.4e-09 37.3 4.9 3.1e-09 37.0 4.9 1.1 1 0 0 1 1 1 1 COPI associated protein NrsF PF06532.11 OEU14668.1 - 0.0079 15.9 5.5 0.018 14.8 5.4 1.5 1 1 0 1 1 1 1 Negative regulator of sigma F LRR_8 PF13855.6 OEU14669.1 - 4.6e-23 80.7 42.2 1.1e-05 25.1 0.4 6.5 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OEU14669.1 - 2.9e-12 46.6 48.9 0.0023 18.3 2.8 8.2 3 1 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OEU14669.1 - 0.003 17.1 11.5 0.11 12.0 0.2 3.2 2 1 0 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 OEU14669.1 - 0.018 15.5 34.3 3.5 8.6 0.3 10.9 13 0 0 13 13 13 0 Leucine Rich Repeat LRRNT_2 PF08263.12 OEU14669.1 - 0.097 13.0 2.6 0.32 11.3 2.6 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain GSDH PF07995.11 OEU14670.1 - 2.3e-36 125.8 0.0 4.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU14670.1 - 4.2e-10 39.3 0.5 1.6e-09 37.4 0.4 2.0 2 0 0 2 2 2 1 PKD domain Conotoxin PF02950.17 OEU14670.1 - 1.8 9.6 9.2 0.3 12.1 4.0 2.5 2 0 0 2 2 2 0 Conotoxin GSDH PF07995.11 OEU14672.1 - 2e-33 116.1 0.1 4.5e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU14672.1 - 1.9e-12 46.8 0.2 4.5e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 PKD domain CppA_C PF14507.6 OEU14674.1 - 0.021 15.5 12.2 4.2 8.2 0.6 4.6 1 1 2 3 3 3 0 CppA C-terminal UPF1_Zn_bind PF09416.10 OEU14675.1 - 0.046 13.7 0.4 0.083 12.9 0.4 1.4 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Cupin_8 PF13621.6 OEU14676.1 - 1.1e-17 64.6 0.4 1.2e-17 64.4 0.4 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU14676.1 - 1.8e-06 27.7 0.0 2.6e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OEU14676.1 - 0.0026 18.2 0.0 0.0039 17.6 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OEU14676.1 - 0.024 14.4 0.1 0.049 13.4 0.0 1.5 2 0 0 2 2 2 0 Cupin domain Thioredoxin PF00085.20 OEU14677.1 - 1e-06 28.7 1.0 2.9e-06 27.2 0.2 2.2 2 1 0 2 2 2 1 Thioredoxin zn-ribbon_14 PF16503.5 OEU14677.1 - 0.11 12.0 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon Glutaredoxin PF00462.24 OEU14677.1 - 0.12 12.6 0.1 0.36 11.1 0.1 1.9 1 0 0 1 1 1 0 Glutaredoxin 2OG-FeII_Oxy_3 PF13640.6 OEU14679.1 - 4.1e-13 50.0 0.0 7.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSF_DNA-bind PF00447.17 OEU14681.1 - 2.6e-16 60.0 0.2 4.4e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding LicD PF04991.13 OEU14683.1 - 0.0097 16.1 6.4 0.0097 16.1 6.4 1.9 1 1 0 2 2 2 1 LicD family SOBP PF15279.6 OEU14683.1 - 4.1 7.9 17.8 1.3 9.5 11.9 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein CreD PF06123.12 OEU14683.1 - 4.2 6.0 5.2 7.1 5.3 5.2 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD CTU2 PF10288.9 OEU14684.1 - 8.3 6.7 10.5 16 5.8 1.4 3.0 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 Pkinase PF00069.25 OEU14685.1 - 2.2e-13 50.2 0.0 3.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU14685.1 - 6.5e-06 25.2 0.0 7.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OEU14685.1 - 0.00013 21.3 0.0 0.00025 20.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Aa_trans PF01490.18 OEU14686.1 - 4.3e-42 144.3 13.9 5.3e-42 144.0 13.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 2OG-FeII_Oxy_5 PF13759.6 OEU14686.1 - 0.099 13.1 0.3 2.5 8.5 0.1 2.4 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase SPRY PF00622.28 OEU14687.1 - 8.1e-07 29.2 0.6 0.0035 17.4 0.1 2.5 2 0 0 2 2 2 2 SPRY domain Methyltransf_16 PF10294.9 OEU14688.1 - 4.2e-22 78.7 0.1 7e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OEU14688.1 - 4.5e-05 23.1 0.1 9.4e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OEU14688.1 - 0.00029 21.5 2.1 0.00061 20.5 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 OEU14688.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OEU14688.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OEU14688.1 - 0.0097 15.7 0.0 0.029 14.1 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein SprT-like PF10263.9 OEU14689.1 - 4e-26 91.1 0.0 6.3e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 OEU14689.1 - 8.3e-06 25.6 1.7 1.8e-05 24.6 1.7 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain zf-DNA_Pol PF08996.10 OEU14689.1 - 0.0016 18.2 0.6 0.0022 17.8 0.6 1.2 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger HMG_box PF00505.19 OEU14689.1 - 0.17 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Hydrolase_4 PF12146.8 OEU14690.1 - 5.4e-06 25.8 0.0 6.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU14690.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family CSD PF00313.22 OEU14691.1 - 1.1e-21 76.5 1.6 1.6e-21 75.9 1.6 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU14691.1 - 0.00097 18.8 0.4 0.0017 18.0 0.4 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain DUF1325 PF07039.11 OEU14692.1 - 1.7e-16 60.5 0.0 3.1e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain ING PF12998.7 OEU14692.1 - 4.9e-14 52.8 3.8 8.8e-14 51.9 2.1 2.2 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding CAP_C PF08603.11 OEU14693.1 - 6.4e-46 155.8 5.4 1e-45 155.2 5.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 OEU14693.1 - 8.6e-46 156.9 0.0 1.2e-45 156.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal LON_substr_bdg PF02190.16 OEU14694.1 - 2.7e-08 33.9 0.0 5.9e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain BCDHK_Adom3 PF10436.9 OEU14695.1 - 3.7e-39 134.2 0.9 5.1e-39 133.7 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OEU14695.1 - 1.8e-10 41.3 0.0 4.8e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OEU14695.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YolD PF08863.10 OEU14696.1 - 0.0073 16.3 5.8 0.022 14.8 5.8 1.8 1 1 0 1 1 1 1 YolD-like protein Retrotran_gag_2 PF14223.6 OEU14696.1 - 0.018 14.7 1.0 0.042 13.5 0.6 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type C2-set PF05790.15 OEU14696.1 - 0.79 9.9 4.7 2.5 8.3 1.1 2.4 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Med13_C PF06333.12 OEU14697.1 - 0.014 14.7 7.9 0.075 12.3 7.4 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain ETRAMP PF09716.10 OEU14697.1 - 4.4 7.4 8.7 1.4e+02 2.7 9.9 2.6 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Nse4_C PF08743.10 OEU14698.1 - 2.9e-24 85.1 0.0 2.5e-23 82.1 0.0 2.3 2 0 0 2 2 2 1 Nse4 C-terminal RRM_1 PF00076.22 OEU14699.1 - 3.3e-65 215.8 6.5 1.1e-18 66.8 0.1 7.5 6 1 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU14699.1 - 1.2e-05 24.9 0.0 0.0076 15.8 0.0 3.8 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU14699.1 - 0.0033 17.5 0.0 4.2 7.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif Mtr2 PF10429.9 OEU14699.1 - 0.012 15.6 3.3 0.026 14.5 2.6 1.9 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 Nup35_RRM_2 PF14605.6 OEU14699.1 - 0.032 14.2 0.0 0.7 9.9 0.1 3.0 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif NAM-associated PF14303.6 OEU14699.1 - 0.034 14.9 0.0 0.034 14.9 0.0 6.2 4 3 1 5 5 5 0 No apical meristem-associated C-terminal domain Ammonium_transp PF00909.21 OEU14700.1 - 3.2e-117 391.6 28.0 3.6e-117 391.4 28.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E7R PF17467.2 OEU14700.1 - 0.024 14.8 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 Viral Protein E7 LRR_8 PF13855.6 OEU14701.1 - 5.7e-17 61.2 16.4 1.9e-09 37.1 2.3 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OEU14701.1 - 1.1e-12 47.9 18.0 0.00015 22.1 0.6 4.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14701.1 - 8.5e-07 28.7 14.5 0.82 10.5 0.1 6.4 5 2 2 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU14701.1 - 0.11 12.6 10.8 2.7 8.3 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.6 OEU14701.1 - 1.1 8.7 3.2 2.3 7.7 1.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeat APG6 PF04111.12 OEU14702.1 - 1.2e-11 44.9 0.0 4.5e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OEU14702.1 - 2.8e-05 24.7 9.2 2.8e-05 24.7 9.2 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region CobU PF02283.16 OEU14702.1 - 0.0031 17.1 0.2 0.0031 17.1 0.2 2.4 4 0 0 4 4 4 1 Cobinamide kinase / cobinamide phosphate guanyltransferase PseudoU_synth_2 PF00849.22 OEU14703.1 - 1.1e-28 100.4 0.1 1.4e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2220 PF09983.9 OEU14703.1 - 0.079 12.3 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) ELFV_dehydrog PF00208.21 OEU14704.1 - 2.4e-38 132.2 0.0 1.3e-37 129.8 0.0 1.9 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OEU14704.1 - 1.1e-34 119.1 0.0 1.8e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPA PF08616.10 OEU14704.1 - 0.00029 20.7 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis 2-Hacid_dh_C PF02826.19 OEU14704.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 OEU14704.1 - 0.059 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase K_oxygenase PF13434.6 OEU14704.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-RVT PF13966.6 OEU14706.1 - 0.021 15.5 1.0 0.021 15.5 1.0 2.8 3 1 0 3 3 3 0 zinc-binding in reverse transcriptase Trypsin PF00089.26 OEU14707.1 - 4.1e-33 115.1 1.0 4.9e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 OEU14707.1 - 7.3e-05 23.7 0.0 0.00023 22.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Toxin_19 PF08088.12 OEU14707.1 - 0.23 11.6 9.8 0.53 10.5 9.8 1.6 1 0 0 1 1 1 0 Conotoxin I-superfamily Conotoxin_I2 PF17557.2 OEU14707.1 - 0.51 10.5 10.7 1.2 9.3 10.7 1.6 1 0 0 1 1 1 0 I2-superfamily conotoxins Trypsin PF00089.26 OEU14708.1 - 8.7e-33 114.0 0.0 5.9e-32 111.3 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU14708.1 - 0.00039 21.4 0.0 0.0014 19.6 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain TPT PF03151.16 OEU14710.1 - 2.4e-89 299.5 15.4 2.7e-89 299.3 15.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU14710.1 - 1.5e-08 34.9 27.8 0.00019 21.6 7.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OEU14710.1 - 0.0018 17.5 4.0 0.0018 17.5 4.0 2.2 2 1 1 3 3 3 1 UAA transporter family RRM_1 PF00076.22 OEU14711.1 - 6.3e-05 22.7 0.0 0.00095 18.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_anti-like PF12869.7 OEU14711.1 - 0.014 15.0 3.3 0.014 15.0 3.3 1.6 2 0 0 2 2 2 0 tRNA_anti-like ORC3_N PF07034.11 OEU14711.1 - 0.12 11.5 0.3 0.2 10.8 0.3 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Actin PF00022.19 OEU14712.1 - 1.7e-09 36.8 0.0 0.00044 19.0 0.0 2.7 1 1 1 2 2 2 2 Actin zf-met PF12874.7 OEU14713.1 - 2.3e-05 24.6 2.4 4e-05 23.9 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OEU14713.1 - 0.00065 19.9 2.9 0.0011 19.1 2.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 OEU14713.1 - 0.018 15.6 1.3 0.018 15.6 1.3 2.2 2 0 0 2 2 2 0 AAA domain zf-U1 PF06220.12 OEU14713.1 - 0.028 14.2 2.9 0.058 13.2 2.9 1.4 1 0 0 1 1 1 0 U1 zinc finger SNRNP27 PF08648.12 OEU14713.1 - 0.046 13.8 1.8 0.21 11.7 1.8 2.2 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins RhoGEF67_u2 PF16614.5 OEU14713.1 - 0.33 11.1 2.2 0.91 9.6 2.2 1.7 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 DUF4829 PF16111.5 OEU14713.1 - 1.8 9.3 8.5 0.35 11.7 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4829) NUMOD3 PF07460.11 OEU14714.1 - 1.9e-13 50.4 26.4 6.4e-07 29.5 0.2 5.5 4 2 2 6 6 6 4 NUMOD3 motif (2 copies) SHOCT PF09851.9 OEU14714.1 - 0.13 12.0 4.5 2 8.3 2.4 2.8 2 0 0 2 2 2 0 Short C-terminal domain GerD PF17898.1 OEU14714.1 - 0.42 10.6 7.3 0.12 12.4 3.4 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain CreD PF06123.12 OEU14714.1 - 1.1 7.9 4.7 0.46 9.2 1.8 1.7 2 0 0 2 2 2 0 Inner membrane protein CreD DUF2285 PF10074.9 OEU14714.1 - 2.4 8.8 5.8 4.1 8.1 0.8 3.2 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2285) DUF1299 PF06975.11 OEU14714.1 - 5.9 7.1 7.4 0.61 10.2 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) DUF2631 PF10939.8 OEU14715.1 - 0.0064 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2631) PhyH PF05721.13 OEU14715.1 - 0.13 12.5 0.5 6.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) rve PF00665.26 OEU14717.1 - 0.041 14.1 0.0 0.062 13.5 0.0 1.4 1 1 0 1 1 1 0 Integrase core domain NAD_binding_10 PF13460.6 OEU14719.1 - 0.00046 20.1 0.0 0.0078 16.1 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding DUF4377 PF14302.6 OEU14719.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) NIF PF03031.18 OEU14719.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase NmrA PF05368.13 OEU14719.1 - 0.44 10.1 1.8 41 3.6 0.0 2.9 3 0 0 3 3 3 0 NmrA-like family TFIIF_beta PF02270.15 OEU14721.1 - 1.8e-18 66.4 0.2 3e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OEU14721.1 - 8e-10 39.5 0.5 1.6e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus DUF3591 PF12157.8 OEU14721.1 - 0.0051 15.5 0.1 0.0087 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Tau95 PF09734.9 OEU14721.1 - 0.013 16.3 1.0 0.023 15.5 0.8 1.6 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain SCPU PF05229.15 OEU14721.1 - 0.017 15.5 0.1 0.067 13.6 0.0 1.9 1 1 0 1 1 1 0 Spore Coat Protein U domain DUF3520 PF12034.8 OEU14721.1 - 0.13 12.4 0.4 0.2 11.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) Form_Nir_trans PF01226.17 OEU14722.1 - 2.8e-70 236.4 22.3 2.8e-70 236.4 22.3 1.4 2 0 0 2 2 2 1 Formate/nitrite transporter Homeobox_KN PF05920.11 OEU14723.1 - 7.2e-08 32.2 0.1 9.8e-08 31.8 0.1 1.3 1 1 0 1 1 1 1 Homeobox KN domain HCMV_UL124 PF17609.2 OEU14723.1 - 0.13 12.4 0.0 0.15 12.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function TPR_12 PF13424.6 OEU14724.1 - 4.5e-81 267.2 14.5 1.9e-17 63.3 0.1 9.2 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_10 PF13374.6 OEU14724.1 - 2.2e-62 205.4 18.7 1.8e-06 27.6 0.0 12.3 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_1 PF00515.28 OEU14724.1 - 4.5e-55 181.4 25.7 9.5e-06 25.2 0.1 13.7 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_2 PF07719.17 OEU14724.1 - 1e-46 153.3 24.7 0.0016 18.4 0.1 13.5 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_8 PF13181.6 OEU14724.1 - 3.8e-35 117.1 25.3 0.00022 21.2 0.1 13.7 15 0 0 15 15 13 7 Tetratricopeptide repeat TPR_7 PF13176.6 OEU14724.1 - 2.3e-29 99.2 19.2 0.0025 17.7 0.0 12.6 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU14724.1 - 1.4e-26 93.7 0.7 2.1e-15 56.9 0.1 4.3 2 1 1 4 4 4 3 MalT-like TPR region TPR_11 PF13414.6 OEU14724.1 - 5.1e-17 61.3 22.2 0.0092 15.6 0.1 10.6 9 1 1 10 10 10 6 TPR repeat TPR_14 PF13428.6 OEU14724.1 - 4.1e-15 55.2 4.4 0.43 11.5 0.1 9.8 9 2 2 11 11 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU14724.1 - 4.9e-13 49.5 2.7 0.0069 17.0 0.1 7.6 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU14724.1 - 5.2e-13 48.7 13.6 1 10.1 0.0 11.6 13 0 0 13 13 12 2 Tetratricopeptide repeat SNAP PF14938.6 OEU14724.1 - 5.4e-13 49.0 7.8 9.4e-08 31.8 2.8 4.4 4 1 1 5 5 5 3 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 OEU14724.1 - 1.1e-10 41.8 9.5 0.0026 18.2 0.2 6.7 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU14724.1 - 4.6e-07 29.8 9.0 0.48 10.9 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat MIT PF04212.18 OEU14724.1 - 7.3e-07 29.2 21.4 4.3 7.5 0.0 9.5 8 1 2 10 10 10 1 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 OEU14724.1 - 1.4e-05 24.8 15.8 0.51 10.0 0.7 6.4 1 1 3 5 5 5 2 26S proteasome subunit RPN7 ANAPC3 PF12895.7 OEU14724.1 - 2.5e-05 24.4 16.6 3.1 8.1 2.7 7.3 3 2 2 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OEU14724.1 - 0.00012 22.2 2.8 1.9 8.7 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU14724.1 - 0.00032 20.3 2.8 7.7 5.9 0.1 4.9 2 2 3 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_15 PF13429.6 OEU14724.1 - 0.00098 18.4 4.2 8.3 5.5 0.1 6.1 4 2 1 7 7 7 0 Tetratricopeptide repeat TruD PF01142.18 OEU14724.1 - 0.013 14.4 0.0 0.067 12.0 0.0 2.1 1 1 0 2 2 2 0 tRNA pseudouridine synthase D (TruD) TPR_4 PF07721.14 OEU14724.1 - 0.024 15.2 0.0 90 4.1 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 OEU14724.1 - 0.065 13.3 7.2 0.66 10.0 0.2 4.6 4 1 1 5 5 4 0 Protein of unknown function (DUF627) Peripla_BP_2 PF01497.18 OEU14724.1 - 0.066 12.8 0.1 0.81 9.2 0.0 2.2 1 1 0 2 2 2 0 Periplasmic binding protein TPR_21 PF09976.9 OEU14724.1 - 0.42 10.3 3.8 1.2 8.8 0.3 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain PPR PF01535.20 OEU14724.1 - 1.3 9.5 15.5 39 4.8 0.1 7.6 10 0 0 10 10 7 0 PPR repeat CRCB PF02537.15 OEU14726.1 - 3.9e-21 75.2 2.0 4.9e-21 74.9 2.0 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Brix PF04427.18 OEU14727.1 - 3.2e-36 125.3 0.1 4.4e-36 124.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain PPL5 PF18168.1 OEU14727.1 - 0.0063 15.9 5.3 0.011 15.1 5.3 1.3 1 0 0 1 1 1 1 Prim-pol family 5 ATP-synt_E PF05680.12 OEU14727.1 - 0.4 11.0 10.3 0.71 10.3 9.4 1.9 1 1 0 1 1 1 0 ATP synthase E chain FGF-BP1 PF06473.12 OEU14727.1 - 0.58 10.0 6.5 1.2 9.0 6.5 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CNDH2_C PF16858.5 OEU14727.1 - 4.4 7.1 15.5 8.5 6.1 15.5 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_repr_REX1B PF14966.6 OEU14728.1 - 7.3e-16 58.6 0.6 3.5e-15 56.4 0.6 2.2 1 1 0 1 1 1 1 DNA repair REX1-B Cyclin_C PF02984.19 OEU14728.1 - 0.082 13.0 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Pkinase PF00069.25 OEU14729.1 - 5e-73 245.7 0.0 5.8e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14729.1 - 3.3e-35 121.6 0.0 4.3e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU14729.1 - 0.005 16.2 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OEU14729.1 - 0.013 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OEU14729.1 - 0.023 14.3 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family LRR_8 PF13855.6 OEU14730.1 - 1.4e-23 82.4 22.6 2e-07 30.7 0.9 5.4 3 2 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OEU14730.1 - 6.7e-17 61.3 22.6 0.00051 20.4 0.5 6.6 2 1 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14730.1 - 2.1e-08 33.6 27.0 0.86 10.4 0.0 10.1 11 1 1 12 12 12 5 Leucine Rich Repeat LRR_9 PF14580.6 OEU14730.1 - 0.00023 20.7 1.5 3.3 7.2 0.0 3.4 1 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OEU14730.1 - 0.011 15.7 23.8 2.7 8.3 0.4 8.2 9 0 0 9 9 9 0 Leucine Rich repeat PseudoU_synth_1 PF01416.20 OEU14731.1 - 3.2e-21 75.8 0.0 5.9e-13 49.2 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase Myb_DNA-binding PF00249.31 OEU14732.1 - 3.8e-22 78.2 8.9 3.7e-12 46.2 2.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU14732.1 - 4.2e-20 71.7 7.6 2.4e-13 50.1 4.8 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OEU14732.1 - 0.011 15.7 0.6 0.026 14.6 0.6 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CHAD PF05235.14 OEU14732.1 - 0.023 14.7 1.0 0.025 14.6 1.0 1.1 1 0 0 1 1 1 0 CHAD domain DUF722 PF05263.11 OEU14732.1 - 0.06 13.6 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Myb_DNA-bind_4 PF13837.6 OEU14732.1 - 0.074 13.4 7.3 0.63 10.5 1.1 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SAMP PF05924.11 OEU14732.1 - 0.37 10.1 4.3 8.9 5.8 0.0 2.6 2 0 0 2 2 2 0 SAMP Motif MADF_DNA_bdg PF10545.9 OEU14732.1 - 0.4 11.0 3.8 0.65 10.4 2.9 1.8 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_Cef PF11831.8 OEU14733.1 - 5.2e-28 98.2 4.3 5.2e-28 98.2 4.3 2.4 1 1 1 2 2 2 1 pre-mRNA splicing factor component HALZ PF02183.18 OEU14733.1 - 0.027 14.7 2.2 0.84 9.9 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPK_catalytic PF04263.16 OEU14733.1 - 0.12 12.5 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Asparaginase PF00710.20 OEU14734.1 - 1e-49 168.7 0.0 1.5e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OEU14734.1 - 1.3e-26 93.0 0.1 2e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Chordopox_G2 PF05796.12 OEU14734.1 - 0.17 11.3 0.0 0.53 9.7 0.0 1.8 1 1 1 2 2 2 0 Chordopoxvirus protein G2 Glyco_transf_64 PF09258.10 OEU14737.1 - 9.1e-17 61.2 0.0 5.4e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 64 domain CSTF2_hinge PF14327.6 OEU14737.1 - 0.14 12.6 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 XPC-binding PF09280.11 OEU14737.1 - 0.15 11.8 0.9 22 4.9 0.0 2.9 3 0 0 3 3 3 0 XPC-binding domain Pkinase PF00069.25 OEU14738.1 - 1.7e-48 165.3 0.0 8.1e-48 163.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14738.1 - 6.1e-19 68.3 0.0 1.2e-18 67.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU14738.1 - 0.028 13.7 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OEU14738.1 - 0.056 12.8 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5529 PF17669.1 OEU14739.1 - 0.041 13.9 8.0 0.43 10.6 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5529) 30K_MP_C_Ter PF11330.8 OEU14739.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Dynactin PF12455.8 OEU14739.1 - 0.15 11.3 1.2 0.28 10.4 1.0 1.5 2 0 0 2 2 2 0 Dynein associated protein Pribosyl_synth PF14572.6 OEU14740.1 - 0.024 14.7 1.7 0.04 13.9 0.7 1.8 2 1 0 2 2 2 0 Phosphoribosyl synthetase-associated domain Pox_Rap94 PF03294.14 OEU14740.1 - 0.033 12.3 0.3 0.044 11.9 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 zf-A20 PF01754.16 OEU14740.1 - 0.22 11.5 2.2 0.44 10.5 2.2 1.5 1 0 0 1 1 1 0 A20-like zinc finger eIF-3_zeta PF05091.12 OEU14743.1 - 6.1e-136 454.4 0.0 6.9e-136 454.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 OEU14743.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus UCH PF00443.29 OEU14745.1 - 9e-45 153.2 0.8 5.9e-24 84.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU14745.1 - 4e-17 62.8 4.5 2.2e-13 50.5 0.1 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OEU14745.1 - 0.00021 20.9 1.7 0.66 9.4 0.4 3.4 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase bacHORMA_2 PF18173.1 OEU14746.1 - 0.052 13.4 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial HORMA domain 2 DUF4876 PF16215.5 OEU14746.1 - 0.097 12.7 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4876) COX14 PF14880.6 OEU14746.1 - 0.61 10.0 2.4 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RNase_T PF00929.24 OEU14748.1 - 5.3e-17 62.8 0.0 7.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OEU14748.1 - 0.071 12.8 0.0 1 9.0 0.0 2.3 1 1 0 1 1 1 0 3'-5' exonuclease PPDK_N PF01326.19 OEU14749.1 - 7.4e-67 225.9 0.0 1.3e-66 225.1 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OEU14749.1 - 8.3e-20 70.3 0.1 1.9e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF3810 PF12725.7 OEU14750.1 - 0.075 12.4 0.2 0.075 12.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Myc_N PF01056.18 OEU14751.1 - 0.12 12.3 6.8 0.14 12.1 6.8 1.0 1 0 0 1 1 1 0 Myc amino-terminal region PAH PF02671.21 OEU14752.1 - 2.4e-39 133.2 2.7 4.2e-18 65.2 2.6 3.4 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OEU14752.1 - 9.4e-20 70.5 0.6 1.8e-19 69.6 0.6 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 OEU14753.1 - 0.0044 16.8 0.3 0.0087 15.8 0.3 1.5 1 1 0 1 1 1 1 C-terminal domain of Sin3a protein PMBR PF09373.10 OEU14753.1 - 0.12 12.5 0.3 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat Astro_capsid_p PF12226.8 OEU14753.1 - 0.19 10.8 2.2 0.23 10.6 2.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 OEU14753.1 - 3 7.5 9.2 1.1 9.0 7.0 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OEU14753.1 - 3.7 6.8 8.1 6.6 6.0 8.1 1.4 1 0 0 1 1 1 0 NOA36 protein NifU PF01106.17 OEU14754.1 - 9.4e-23 80.1 0.3 1e-22 80.0 0.3 1.0 1 0 0 1 1 1 1 NifU-like domain TRAM_LAG1_CLN8 PF03798.16 OEU14755.1 - 1.1e-25 90.5 25.5 8.6e-25 87.6 25.5 2.2 1 1 0 1 1 1 1 TLC domain DUF4834 PF16118.5 OEU14755.1 - 2.6 9.0 7.0 3.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4477 PF14780.6 OEU14756.1 - 0.0022 17.6 17.4 0.0086 15.7 4.3 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4477) Band_3_cyto PF07565.13 OEU14756.1 - 0.017 15.0 0.6 0.017 15.0 0.6 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain YL1 PF05764.13 OEU14756.1 - 4.7 7.3 34.7 0.07 13.2 19.3 2.5 1 1 0 2 2 2 0 YL1 nuclear protein EGF PF00008.27 OEU14758.1 - 0.0033 17.7 36.0 0.02 15.2 0.6 5.0 4 1 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 OEU14758.1 - 0.023 15.1 7.4 0.023 15.1 7.4 4.8 3 2 0 3 3 3 0 EGF-like domain Choline_kinase PF01633.20 OEU14759.1 - 2.5e-21 76.3 3.3 2.5e-21 76.3 3.3 2.5 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 OEU14759.1 - 8e-10 39.0 0.0 6.5e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU14759.1 - 0.00032 20.1 0.5 0.00073 19.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain MID_MedPIWI PF18296.1 OEU14759.1 - 0.11 12.3 0.2 0.11 12.3 0.2 3.0 2 1 0 3 3 3 0 MID domain of medPIWI Glyco_hydro_99 PF16317.5 OEU14760.1 - 5e-17 62.0 0.8 5e-14 52.2 0.4 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 99 CBM_6 PF03422.15 OEU14760.1 - 2.6e-07 31.0 0.3 6.8e-07 29.6 0.3 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) B_lectin PF01453.24 OEU14760.1 - 2e-06 28.3 10.3 0.03 14.9 0.0 4.1 2 2 2 4 4 4 3 D-mannose binding lectin Endotoxin_C PF03944.14 OEU14760.1 - 0.098 13.0 2.8 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 delta endotoxin PP2C PF00481.21 OEU14761.1 - 8.2e-45 153.4 0.1 9.3e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C ATP-synt_ab PF00006.25 OEU14763.1 - 2.8e-104 347.4 0.0 4.4e-104 346.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OEU14763.1 - 1.1e-37 128.6 0.0 2e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OEU14763.1 - 3.5e-15 56.3 1.4 5.2e-15 55.7 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Tape_meas_lam_C PF09718.10 OEU14763.1 - 0.08 13.1 0.0 9.6 6.4 0.0 2.8 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RVT_1 PF00078.27 OEU14764.1 - 5.5e-08 32.6 2.0 2.5e-07 30.4 0.0 2.9 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU14764.1 - 0.00018 21.1 0.0 0.00054 19.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU14764.1 - 0.091 13.5 1.9 0.33 11.7 1.9 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 OEU14765.1 - 1.1e-07 31.7 0.1 4.9e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU14765.1 - 0.0012 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU14765.1 - 0.074 13.8 1.2 0.36 11.6 1.2 2.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase LBR_tudor PF09465.10 OEU14765.1 - 0.12 12.3 0.2 0.32 10.8 0.2 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF1199 PF06712.11 OEU14765.1 - 0.52 10.4 2.5 2.3 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) SlyX PF04102.12 OEU14765.1 - 9 7.0 9.9 0.17 12.5 0.3 3.4 3 0 0 3 3 3 0 SlyX PGK PF00162.19 OEU14766.1 - 2.3e-142 474.4 0.0 2.6e-142 474.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Pkinase PF00069.25 OEU14767.1 - 5.1e-58 196.5 0.0 1.6e-54 185.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14767.1 - 1.2e-38 132.9 0.0 1.3e-36 126.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU14767.1 - 4.4e-06 25.7 2.7 1.3e-05 24.1 2.7 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU14767.1 - 0.00036 20.5 0.9 0.00055 19.9 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4805 PF16063.5 OEU14767.1 - 0.057 12.8 1.7 0.11 11.9 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) FAM176 PF14851.6 OEU14767.1 - 0.15 11.7 3.5 0.25 11.0 3.5 1.3 1 0 0 1 1 1 0 FAM176 family DUF775 PF05603.12 OEU14767.1 - 0.36 10.4 5.4 0.61 9.6 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Bromodomain PF00439.25 OEU14768.1 - 3.8e-11 42.9 0.0 4.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 OEU14769.1 - 4.2e-18 65.2 0.9 4.5e-18 65.1 0.9 1.0 1 0 0 1 1 1 1 Bromodomain Vpu PF00558.19 OEU14770.1 - 0.84 9.5 3.0 7.7 6.4 0.3 2.4 2 0 0 2 2 2 0 Vpu protein PDZ PF00595.24 OEU14771.1 - 2.1e-06 28.0 0.1 6.5e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU14771.1 - 0.0063 16.8 0.2 0.021 15.1 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU14771.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PBP1_TM PF14812.6 OEU14771.1 - 6.1 7.3 9.1 18 5.8 1.0 3.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glutaredoxin PF00462.24 OEU14772.1 - 1.1e-36 124.9 0.0 5.4e-17 61.8 0.0 3.4 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 OEU14772.1 - 3.3e-08 33.4 0.0 1.1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin SH3BGR PF04908.15 OEU14772.1 - 0.00047 20.3 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein OST3_OST6 PF04756.13 OEU14772.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RdRP PF05183.12 OEU14772.1 - 0.051 12.2 0.0 0.15 10.7 0.0 1.6 1 1 0 1 1 1 0 RNA dependent RNA polymerase Thioredoxin_2 PF13098.6 OEU14772.1 - 0.06 13.8 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OEU14772.1 - 0.094 12.8 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain MFS_1 PF07690.16 OEU14773.1 - 1.9e-10 40.2 30.8 8.6e-07 28.2 10.9 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 OEU14773.1 - 1.2e-07 31.5 3.4 1.2e-07 31.5 3.4 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Chloroa_b-bind PF00504.21 OEU14774.1 - 3.4e-30 105.7 0.3 4.7e-30 105.2 0.3 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein GFO_IDH_MocA PF01408.22 OEU14775.1 - 0.00037 21.3 0.0 0.00085 20.1 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_synthase PF02540.17 OEU14777.1 - 0.00036 19.7 0.1 0.00073 18.7 0.1 1.4 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 OEU14777.1 - 0.013 15.2 0.6 0.021 14.5 0.6 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 OEU14777.1 - 0.024 14.1 0.1 5.4 6.5 0.1 2.5 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OEU14777.1 - 0.026 13.3 0.2 0.07 11.9 0.2 1.7 1 1 0 1 1 1 0 tRNA methyl transferase NPBW PF15180.6 OEU14777.1 - 0.086 12.7 0.1 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Neuropeptides B and W SR-25 PF10500.9 OEU14777.1 - 1.1 8.9 9.9 1.2 8.7 3.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TLD PF07534.16 OEU14778.1 - 0.066 13.4 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 TLD Xan_ur_permease PF00860.20 OEU14779.1 - 8.6e-69 232.1 28.4 1.3e-48 165.7 9.2 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 OEU14779.1 - 7.5e-08 31.5 2.8 1.6e-07 30.5 2.8 1.5 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 OEU14779.1 - 0.00017 22.0 1.2 0.00017 22.0 1.2 3.2 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF2157 PF09925.9 OEU14779.1 - 5.1 6.9 8.3 1 9.1 3.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) CobD_Cbib PF03186.13 OEU14780.1 - 3.5e-72 242.9 0.0 7e-72 241.9 0.0 1.5 1 0 0 1 1 1 1 CobD/Cbib protein CbiZ PF01955.18 OEU14780.1 - 2.3e-38 132.2 0.5 2.1e-33 116.0 1.7 2.8 1 1 1 2 2 2 2 Adenosylcobinamide amidohydrolase CENP-B_dimeris PF09026.10 OEU14781.1 - 2.6 8.5 7.2 1.1 9.6 1.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CBS PF00571.28 OEU14782.1 - 1.3e-23 83.1 0.3 2.1e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain EF-hand_1 PF00036.32 OEU14782.1 - 5e-09 35.1 2.4 0.00044 19.6 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU14782.1 - 1e-08 35.5 3.5 2.7e-08 34.1 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OEU14782.1 - 2.8e-06 27.0 2.4 4.3e-05 23.3 1.0 2.5 2 1 1 3 3 3 2 EF-hand domain pair DHHA1 PF02272.19 OEU14782.1 - 0.00016 22.1 1.4 0.00054 20.4 0.1 2.3 2 0 0 2 2 2 1 DHHA1 domain EF-hand_5 PF13202.6 OEU14782.1 - 0.00024 20.4 6.2 0.0074 15.7 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OEU14782.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 4.3 5 0 0 5 5 5 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU14782.1 - 0.0056 17.0 2.2 0.01 16.1 0.1 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region FAM176 PF14851.6 OEU14782.1 - 0.16 11.6 1.6 0.24 11.0 1.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF3402 PF11882.8 OEU14782.1 - 0.32 10.1 5.2 0.46 9.5 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) U79_P34 PF03064.16 OEU14782.1 - 0.44 9.9 6.2 0.74 9.1 6.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ATP-synt_C PF00137.21 OEU14783.1 - 9.7e-25 86.7 30.1 3.3e-12 46.6 14.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SR-25 PF10500.9 OEU14784.1 - 0.0019 17.9 11.0 0.0019 17.8 11.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 OEU14784.1 - 0.038 13.7 5.9 0.04 13.6 5.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ABC1 PF03109.16 OEU14785.1 - 6.4e-28 97.3 0.0 1.3e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU14785.1 - 4.2e-05 23.6 5.6 0.0081 16.1 0.3 3.1 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase PF00069.25 OEU14785.1 - 0.00011 21.6 0.0 0.022 14.1 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain GNAT_acetyltr_2 PF13718.6 OEU14786.1 - 2.9e-95 318.0 0.0 8.9e-95 316.4 0.0 1.9 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OEU14786.1 - 1.9e-63 214.3 0.0 1.9e-63 214.3 0.0 1.7 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OEU14786.1 - 5.2e-54 182.8 0.0 1.1e-53 181.8 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 OEU14786.1 - 1.6e-31 108.1 0.0 3.4e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 OEU14786.1 - 0.031 14.5 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU14786.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.31 OEU14787.1 - 2.5e-05 24.3 0.4 6.6e-05 23.0 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4171 PF13775.6 OEU14787.1 - 0.0012 19.3 9.2 0.0012 19.3 9.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4171) FAM193_C PF15914.5 OEU14787.1 - 0.23 11.2 1.2 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 FAM193 family C-terminal RRM_1 PF00076.22 OEU14788.1 - 8.8e-18 63.9 0.0 9.7e-18 63.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU14788.1 - 5.7e-06 26.4 0.0 1.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 OEU14788.1 - 0.013 15.1 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF285 PF03382.14 OEU14789.1 - 3.1e-68 227.1 22.8 6e-38 129.3 6.0 2.3 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Mog1 PF04603.12 OEU14789.1 - 0.19 12.1 0.1 30 5.0 0.0 3.1 3 0 0 3 3 3 0 Ran-interacting Mog1 protein ShK PF01549.24 OEU14789.1 - 3.8 8.1 20.9 0.64 10.6 3.2 3.8 3 1 0 3 3 3 0 ShK domain-like Peptidase_S41 PF03572.18 OEU14790.1 - 1.6e-41 141.7 1.0 3.2e-41 140.7 1.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 OEU14790.1 - 4.9e-10 39.6 0.2 1.2e-09 38.3 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU14790.1 - 9.6e-09 35.5 0.6 2.7e-08 34.1 0.6 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU14790.1 - 1.3e-08 34.5 0.1 3.5e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Sulfotransfer_2 PF03567.14 OEU14791.1 - 4.3e-06 26.8 1.4 4.6e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 Sulfotransferase family DUF2448 PF10476.9 OEU14791.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) PAD_porph PF04371.15 OEU14792.1 - 8.7e-96 320.9 0.1 9.9e-96 320.8 0.1 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase IL1 PF00340.19 OEU14792.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Interleukin-1 / 18 AhpC-TSA_2 PF13911.6 OEU14793.1 - 1.9e-09 37.6 0.0 3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF4776 PF16003.5 OEU14794.1 - 0.1 11.6 8.2 0.16 10.9 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Apis_Csd PF11671.8 OEU14794.1 - 2.6 8.1 9.4 6.3 6.8 9.4 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein LCM PF04072.14 OEU14796.1 - 7.9e-23 81.4 0.0 7.1e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase CRPA PF05745.11 OEU14797.1 - 2.5 8.1 10.1 0.3 11.1 2.4 2.7 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF1996 PF09362.10 OEU14798.1 - 9.3e-36 124.0 1.6 1.8e-35 123.0 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DNA_pol_phi PF04931.13 OEU14798.1 - 0.94 7.5 22.8 1.1 7.3 22.0 1.4 2 0 0 2 2 2 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 OEU14798.1 - 3.4 5.3 6.2 4.4 4.9 6.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Utp14 PF04615.13 OEU14798.1 - 7.1 5.1 12.1 11 4.4 12.1 1.2 1 0 0 1 1 1 0 Utp14 protein Sigma70_ner PF04546.13 OEU14798.1 - 7.8 6.3 13.1 0.89 9.4 7.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Dicty_REP PF05086.12 OEU14798.1 - 7.8 4.3 14.0 11 3.8 14.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RXT2_N PF08595.11 OEU14798.1 - 9.6 6.2 11.2 1.7 8.7 5.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal ParBc PF02195.18 OEU14799.1 - 4.9e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain HA PF03457.14 OEU14800.1 - 1.1e-21 77.0 0.2 1.2e-21 76.8 0.2 1.0 1 0 0 1 1 1 1 Helicase associated domain RRM_1 PF00076.22 OEU14801.1 - 4.6e-18 64.8 0.0 5.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OEU14801.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4788 PF16032.5 OEU14801.1 - 0.025 13.5 0.1 0.17 10.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4788) RRM_7 PF16367.5 OEU14801.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 OEU14801.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif ABC_tran PF00005.27 OEU14804.1 - 1.1e-53 181.5 0.0 3.2e-31 108.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OEU14804.1 - 4.6e-45 154.4 40.7 1.7e-33 116.4 16.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_22 PF13401.6 OEU14804.1 - 9.4e-07 29.2 0.0 0.076 13.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OEU14804.1 - 1.3e-06 28.1 0.3 0.085 12.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 OEU14804.1 - 3.9e-06 26.5 0.6 1.2 8.5 0.1 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU14804.1 - 2.9e-05 24.1 2.1 0.79 9.5 0.1 4.3 4 1 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OEU14804.1 - 7.2e-05 23.2 0.0 0.065 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 OEU14804.1 - 0.00017 21.6 0.1 0.096 12.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU14804.1 - 0.00019 21.3 0.2 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 OEU14804.1 - 0.0011 19.1 1.8 0.019 15.0 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain NACHT PF05729.12 OEU14804.1 - 0.0017 18.3 0.3 2.9 7.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ATP_bind_1 PF03029.17 OEU14804.1 - 0.0018 18.1 0.5 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 OEU14804.1 - 0.0027 18.1 0.3 2.2 8.7 0.1 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OEU14804.1 - 0.0037 16.8 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 OEU14804.1 - 0.0046 16.7 4.0 0.47 10.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 OEU14804.1 - 0.005 16.6 0.0 0.5 10.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU14804.1 - 0.0059 16.8 0.0 4.5 7.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OEU14804.1 - 0.0065 16.5 3.2 0.55 10.3 0.0 3.4 3 0 0 3 3 3 1 Dynamin family AAA_18 PF13238.6 OEU14804.1 - 0.0074 16.8 4.3 0.86 10.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OEU14804.1 - 0.011 15.1 4.0 0.2 11.0 0.2 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 OEU14804.1 - 0.016 14.3 0.2 7.1 5.6 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 OEU14804.1 - 0.026 14.2 0.0 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 OEU14804.1 - 0.051 14.1 6.9 2 8.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 OEU14804.1 - 0.06 12.5 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 OEU14804.1 - 0.068 12.1 0.3 0.92 8.4 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OEU14804.1 - 0.07 12.7 0.6 8.9 5.9 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OEU14804.1 - 7.6 7.0 6.6 3.9 7.9 0.0 3.4 4 0 0 4 4 3 0 RNA helicase zf-MYND PF01753.18 OEU14805.1 - 2.6e-06 27.4 17.3 5.3e-06 26.4 17.3 1.6 1 0 0 1 1 1 1 MYND finger SUIM_assoc PF16619.5 OEU14806.1 - 0.066 13.3 9.9 0.19 11.8 2.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 OEU14806.1 - 1.2 10.1 9.8 1.7 9.6 0.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RF-1 PF00472.20 OEU14807.1 - 1.9e-21 76.2 6.5 2.2e-21 75.9 6.5 1.1 1 0 0 1 1 1 1 RF-1 domain DUF4037 PF13228.6 OEU14807.1 - 0.074 13.9 0.1 0.16 12.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4037) Menin PF05053.13 OEU14808.1 - 0.3 9.4 5.2 0.38 9.0 5.2 1.2 1 0 0 1 1 1 0 Menin ETRAMP PF09716.10 OEU14808.1 - 5.5 7.1 7.0 33 4.6 0.1 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PalH PF08733.10 OEU14809.1 - 0.031 13.3 1.4 0.047 12.7 1.4 1.3 1 1 0 1 1 1 0 PalH/RIM21 TMEM43 PF07787.12 OEU14810.1 - 1.5e-64 217.8 0.0 2.1e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 Nuc_deoxyri_tr3 PF11071.8 OEU14811.1 - 7e-60 201.1 0.0 9e-60 200.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase YtoQ Nuc_deoxyri_tr2 PF15891.5 OEU14811.1 - 0.00015 22.1 0.0 0.00076 19.8 0.0 2.0 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 OEU14811.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase PAD_porph PF04371.15 OEU14812.1 - 1.3e-65 221.8 0.1 1.5e-65 221.6 0.1 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 OEU14812.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase RskA PF10099.9 OEU14815.1 - 0.3 11.3 12.7 0.88 9.8 6.9 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PT PF04886.12 OEU14816.1 - 6.4e-15 54.4 47.3 1.7e+04 -4.6 47.3 3.5 1 1 0 1 1 1 0 PT repeat Glycoprotein_G PF00802.19 OEU14816.1 - 2.3 7.5 19.3 0.36 10.1 11.4 2.0 1 1 1 2 2 2 0 Pneumovirus attachment glycoprotein G Lant_dehydr_C PF14028.6 OEU14817.1 - 0.23 10.9 1.0 0.4 10.2 1.0 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term V_ATPase_I PF01496.19 OEU14819.1 - 1.6 6.5 9.2 1.9 6.3 9.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-LITAF-like PF10601.9 OEU14821.1 - 1.9e-15 56.9 4.9 1.9e-15 56.9 4.9 1.6 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 OEU14821.1 - 0.027 14.4 0.3 0.027 14.4 0.3 2.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DZR PF12773.7 OEU14821.1 - 0.029 14.4 8.5 0.61 10.2 1.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Ogr_Delta PF04606.12 OEU14821.1 - 0.037 14.0 1.1 0.037 14.0 1.1 1.9 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger HC2 PF07382.11 OEU14822.1 - 0.0001 22.5 50.0 0.00018 21.6 50.0 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 PSII_Pbs31 PF18240.1 OEU14823.1 - 2.8e-29 101.4 11.2 2.8e-29 101.4 11.2 2.0 2 0 0 2 2 2 1 Photosystem II Psb31 protein Pkinase_Tyr PF07714.17 OEU14825.1 - 0.00058 19.2 0.1 0.00093 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU14825.1 - 0.0013 18.1 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuclease PF00545.20 OEU14825.1 - 0.018 15.8 0.3 0.076 13.8 0.0 2.2 2 0 0 2 2 2 0 ribonuclease MADF_DNA_bdg PF10545.9 OEU14825.1 - 0.65 10.4 4.6 0.12 12.7 0.8 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FSH1 PF03959.13 OEU14826.1 - 9.4e-20 71.2 0.0 1.7e-17 63.8 0.0 2.4 1 1 1 2 2 2 2 Serine hydrolase (FSH1) PGA_cap PF09587.10 OEU14826.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap RNA_pol_Rpc4 PF05132.14 OEU14826.1 - 0.069 13.6 0.2 10 6.5 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF243 PF03103.17 OEU14826.1 - 0.081 13.2 0.9 0.32 11.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DNA_pol_phi PF04931.13 OEU14826.1 - 2.7 6.0 4.4 3.8 5.5 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3246 PF11596.8 OEU14826.1 - 7.3 5.9 13.0 0.52 9.7 6.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3246) Lipase_GDSL_2 PF13472.6 OEU14827.1 - 2e-19 70.7 0.3 4.2e-18 66.4 0.1 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_18 PF00704.28 OEU14827.1 - 4.7e-19 69.3 0.1 7.8e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipase_GDSL PF00657.22 OEU14827.1 - 6.6e-10 39.3 0.0 2.9e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 OEU14827.1 - 3.8e-08 33.3 0.0 1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal PWWP PF00855.17 OEU14827.1 - 1.1 9.7 3.8 7.5 7.0 0.2 2.5 2 0 0 2 2 2 0 PWWP domain Par3_HAL_N_term PF12053.8 OEU14828.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins NPR3 PF03666.13 OEU14830.1 - 0.00066 18.6 0.4 0.00066 18.6 0.4 6.6 5 2 0 5 5 5 3 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_transf_90 PF05686.12 OEU14832.1 - 3.4e-12 46.0 8.3 1.3e-11 44.1 8.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF4710 PF15828.5 OEU14832.1 - 0.53 10.4 5.4 2.8 8.1 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) HlyIII PF03006.20 OEU14834.1 - 0.093 12.4 2.8 0.13 12.0 2.8 1.1 1 0 0 1 1 1 0 Haemolysin-III related Jak1_Phl PF17887.1 OEU14834.1 - 0.094 12.7 1.5 0.23 11.4 1.5 1.6 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF1275 PF06912.11 OEU14834.1 - 5.7 6.8 6.3 0.62 10.0 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) Galactosyl_T PF01762.21 OEU14835.1 - 0.00013 21.9 0.2 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 Galactosyltransferase APC_N_CC PF16689.5 OEU14835.1 - 0.086 12.9 4.1 1.1 9.4 0.7 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3560 PF12083.8 OEU14835.1 - 0.25 11.5 5.2 6.4 6.9 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Clat_adaptor_s PF01217.20 OEU14836.1 - 2.1e-07 30.9 0.0 7.4e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain HDPD PF02924.14 OEU14836.1 - 0.048 13.8 0.0 0.35 11.0 0.0 2.1 1 1 0 1 1 1 0 Bacteriophage lambda head decoration protein D DUF4570 PF15134.6 OEU14837.1 - 0.13 12.2 2.8 0.32 11.0 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) RRN3 PF05327.11 OEU14838.1 - 0.0051 15.4 5.4 0.007 15.0 5.4 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF4752 PF15944.5 OEU14839.1 - 0.042 13.9 0.2 0.042 13.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) REV PF00424.18 OEU14839.1 - 0.41 10.7 4.1 2.1 8.4 0.6 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) SnoaL PF07366.12 OEU14840.1 - 2.9e-17 62.6 0.0 5.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OEU14840.1 - 0.00038 21.0 0.0 0.00071 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF3275 PF11679.8 OEU14840.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3275) Tocopherol_cycl PF14249.6 OEU14843.1 - 4.6e-06 26.0 0.1 1.8e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Tocopherol cyclase LRR_4 PF12799.7 OEU14844.1 - 0.0049 17.3 14.6 0.25 11.8 2.3 4.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU14844.1 - 0.057 14.0 3.8 21 6.1 0.2 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 OEU14844.1 - 0.1 12.4 7.2 3.7 7.4 0.2 3.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 OEU14844.1 - 1.3 9.3 5.0 4.1 7.7 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat TTL PF03133.15 OEU14845.1 - 0.22 10.6 0.0 0.26 10.4 0.0 1.0 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family CIA30 PF08547.12 OEU14846.1 - 7.4e-11 42.3 0.4 3.1e-10 40.3 0.4 1.9 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) FKBP_C PF00254.28 OEU14848.1 - 1e-27 96.2 0.0 1.2e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Response_reg PF00072.24 OEU14849.1 - 7.2e-20 71.2 0.0 1.6e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OEU14849.1 - 9.4e-18 64.8 1.0 2.1e-17 63.6 1.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OEU14849.1 - 4.2e-06 26.7 0.1 1.3e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OEU14849.1 - 0.00064 19.6 1.4 0.0017 18.2 1.2 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CCDC73 PF15818.5 OEU14849.1 - 0.02 12.8 0.5 0.03 12.2 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family Iso_dh PF00180.20 OEU14850.1 - 1.5e-130 435.4 0.0 1.9e-130 435.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S41 PF03572.18 OEU14851.1 - 5.6e-43 146.4 0.1 8.7e-43 145.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 OEU14851.1 - 1.1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU14851.1 - 0.00011 22.5 0.1 0.0012 19.2 0.1 2.3 2 0 0 2 2 2 1 PDZ domain HSP33 PF01430.19 OEU14851.1 - 0.00022 20.8 0.1 0.00033 20.2 0.1 1.2 1 0 0 1 1 1 1 Hsp33 protein PDZ PF00595.24 OEU14851.1 - 0.0036 17.6 0.2 0.0069 16.7 0.2 1.4 1 0 0 1 1 1 1 PDZ domain DUF3859 PF12975.7 OEU14851.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Tricorn_C1 PF14684.6 OEU14851.1 - 0.074 13.1 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain zf-MYND PF01753.18 OEU14852.1 - 7.1e-06 26.0 14.3 1.7e-05 24.8 14.3 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU14852.1 - 0.022 14.8 3.2 0.053 13.6 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 OEU14852.1 - 0.023 14.6 8.4 0.055 13.4 8.4 1.6 1 0 0 1 1 1 0 HIT zinc finger TEX33 PF15400.6 OEU14852.1 - 0.032 14.7 0.2 0.073 13.6 0.1 1.7 1 1 0 1 1 1 0 Testis-expressed sequence 33 protein family Spore_III_AB PF09548.10 OEU14853.1 - 7.4e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Piwi PF02171.17 OEU14854.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Piwi domain Peptidase_C14 PF00656.22 OEU14857.1 - 1.7e-21 77.3 0.1 2.3e-21 76.9 0.1 1.2 1 1 0 1 1 1 1 Caspase domain Nas2_N PF18265.1 OEU14857.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Nas2 N_terminal domain CaMKII_AD PF08332.10 OEU14859.1 - 1.4e-12 47.9 0.0 1.8e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 OEU14859.1 - 3.2e-08 33.9 0.0 6.2e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain GHMP_kinases_N PF00288.26 OEU14860.1 - 2.2e-12 47.0 0.9 5.2e-12 45.8 0.9 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OEU14860.1 - 8.2e-06 26.1 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GTP_EFTU PF00009.27 OEU14861.1 - 3.8e-50 170.2 0.0 5.4e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 OEU14861.1 - 5.3e-40 136.3 0.0 8.8e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 OEU14861.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OEU14861.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OEU14861.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 ADH_N_2 PF16884.5 OEU14863.1 - 4.1e-21 74.9 0.0 8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OEU14863.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU14863.1 - 0.047 14.7 0.0 0.083 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 OEU14863.1 - 0.062 13.0 0.5 0.097 12.4 0.5 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase zf-MYND PF01753.18 OEU14865.1 - 0.00011 22.2 20.5 0.00032 20.7 20.5 1.8 1 0 0 1 1 1 1 MYND finger Ribosomal_L9_N PF01281.19 OEU14867.1 - 9.4e-16 57.1 0.1 1.6e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain ANAPC2 PF08672.11 OEU14867.1 - 0.018 15.5 0.0 5 7.7 0.1 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 DUF4611 PF15387.6 OEU14867.1 - 0.058 13.6 0.3 0.092 13.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF563 PF04577.14 OEU14868.1 - 3e-08 34.0 0.1 4e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) zf-MYND PF01753.18 OEU14869.1 - 8.6e-05 22.5 9.2 8.6e-05 22.5 9.2 2.5 3 0 0 3 3 3 1 MYND finger PALP PF00291.25 OEU14870.1 - 1.4e-73 247.8 1.4 1.8e-73 247.6 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 OEU14870.1 - 2.8e-05 23.8 0.0 0.0001 22.0 0.0 2.0 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OEU14870.1 - 0.039 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 ACT domain ACT_4 PF13291.6 OEU14870.1 - 0.076 13.6 0.0 0.26 11.9 0.0 1.9 1 0 0 1 1 1 0 ACT domain Dirigent PF03018.14 OEU14871.1 - 0.15 11.8 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Dirigent-like protein DUF4256 PF14066.6 OEU14872.1 - 0.017 14.8 0.3 0.02 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) UBA_6 PF18039.1 OEU14872.1 - 0.039 13.9 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain DUF333 PF03891.15 OEU14874.1 - 0.01 16.0 0.3 0.032 14.4 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF333) PFU PF09070.11 OEU14875.1 - 0.0085 16.4 1.0 1.6 9.0 0.2 2.7 2 0 0 2 2 2 2 PFU (PLAA family ubiquitin binding) SUIM_assoc PF16619.5 OEU14875.1 - 0.029 14.5 27.7 2 8.5 0.2 5.1 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 PUD PF03714.14 OEU14875.1 - 0.071 14.0 6.9 2.7 8.9 0.4 3.8 3 0 0 3 3 3 0 Bacterial pullanase-associated domain DUF4982 PF16355.5 OEU14875.1 - 0.18 11.7 0.1 16 5.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) Inj_translocase PF16928.5 OEU14876.1 - 0.33 10.4 8.1 0.052 13.0 4.1 1.6 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome OTU PF02338.19 OEU14877.1 - 4.6e-16 59.5 0.3 1.9e-15 57.5 0.0 2.0 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OEU14877.1 - 0.004 16.6 7.6 0.036 13.5 0.0 3.0 3 1 0 3 3 3 2 Peptidase C65 Otubain UBA PF00627.31 OEU14877.1 - 0.046 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 UBA/TS-N domain Macoilin PF09726.9 OEU14877.1 - 1.9 6.9 20.7 2.7 6.5 20.7 1.1 1 0 0 1 1 1 0 Macoilin family Fic PF02661.18 OEU14878.1 - 3.4e-08 34.3 0.1 2.5e-07 31.5 0.1 2.6 2 1 0 2 2 2 1 Fic/DOC family zf-RING_2 PF13639.6 OEU14878.1 - 8.9e-06 25.9 7.8 8.9e-06 25.9 7.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU14878.1 - 0.00054 19.8 6.0 0.00054 19.8 6.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU14878.1 - 0.0032 17.7 3.6 0.0032 17.7 3.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OEU14878.1 - 0.024 14.7 0.9 0.024 14.7 0.9 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger ArAE_2_N PF10337.9 OEU14878.1 - 0.16 11.0 1.3 0.26 10.3 1.3 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF5593 PF18007.1 OEU14878.1 - 0.5 11.1 2.8 2.2 9.0 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5593) Guanylate_cyc PF00211.20 OEU14879.1 - 5.2e-48 163.1 0.1 6.4e-47 159.5 0.0 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 OEU14879.1 - 3.3e-27 95.8 7.2 1.3e-26 93.8 7.2 1.9 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_L35Ae PF01247.18 OEU14880.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L35Ae F-box-like PF12937.7 OEU14881.1 - 0.00013 21.8 0.4 0.00027 20.8 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OEU14881.1 - 0.0034 17.2 0.2 0.0094 15.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain TP53IP5 PF15331.6 OEU14882.1 - 0.011 15.8 0.2 0.019 15.2 0.2 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 ETRAMP PF09716.10 OEU14882.1 - 0.057 13.5 0.2 0.057 13.5 0.2 2.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Cpn10 PF00166.21 OEU14882.1 - 0.12 12.4 0.4 0.12 12.4 0.4 2.4 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit STAC2_u1 PF16664.5 OEU14882.1 - 0.21 12.0 3.7 0.41 11.1 3.7 1.4 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CobT PF06213.12 OEU14884.1 - 0.031 13.7 1.8 0.049 13.0 1.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Androgen_recep PF02166.16 OEU14884.1 - 0.085 11.7 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Androgen receptor SDA1 PF05285.12 OEU14884.1 - 0.19 11.1 7.7 0.27 10.6 7.7 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 OEU14884.1 - 0.28 9.2 9.6 0.37 8.8 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 OEU14884.1 - 0.31 9.6 4.5 0.43 9.1 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 OEU14884.1 - 0.73 8.9 9.0 1.2 8.2 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Lactamase_B PF00753.27 OEU14885.1 - 7.7e-19 68.5 0.0 1.1e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PorA PF11271.8 OEU14885.1 - 0.0046 16.3 0.0 0.0083 15.5 0.0 1.4 1 1 0 1 1 1 1 Porin PorA Lactamase_B_2 PF12706.7 OEU14885.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Myb_DNA-binding PF00249.31 OEU14886.1 - 9.7e-26 89.7 3.3 1.8e-10 40.8 0.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU14886.1 - 1.2e-20 73.5 4.5 2.4e-09 37.3 0.0 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OEU14886.1 - 0.35 11.2 3.5 23 5.4 0.2 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HMG_box PF00505.19 OEU14887.1 - 6.1e-27 93.8 9.2 1.1e-20 73.8 1.7 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU14887.1 - 1.7e-15 57.3 7.4 9.3e-11 42.2 0.9 2.1 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 OEU14887.1 - 0.064 13.2 0.0 0.36 10.8 0.0 2.2 2 1 1 3 3 3 0 CHDNT (NUC034) domain DOG1 PF14144.6 OEU14887.1 - 0.11 12.7 0.1 39 4.6 0.0 2.9 3 0 0 3 3 3 0 Seed dormancy control Globin PF00042.22 OEU14888.1 - 5.1e-10 39.9 0.0 6.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Globin Eno-Rase_FAD_bd PF07055.12 OEU14888.1 - 0.071 13.5 0.4 0.27 11.7 0.4 2.0 1 1 0 1 1 1 0 Enoyl reductase FAD binding domain Rsd_AlgQ PF04353.13 OEU14888.1 - 0.076 13.0 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ PSRT PF07636.11 OEU14888.1 - 0.42 10.3 1.0 0.71 9.6 1.0 1.3 1 0 0 1 1 1 0 PSRT Hydrolase_4 PF12146.8 OEU14889.1 - 1e-12 47.9 0.0 4.2e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU14889.1 - 3.4e-10 40.9 0.0 4.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OEU14889.1 - 1.7e-06 28.1 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 OEU14889.1 - 0.0003 20.6 0.0 0.0012 18.7 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU14889.1 - 0.00036 20.3 0.0 0.22 11.1 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 OEU14889.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.6 1 1 1 2 2 2 1 PGAP1-like protein DUF3089 PF11288.8 OEU14889.1 - 0.0031 17.1 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) LIDHydrolase PF10230.9 OEU14889.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 OEU14889.1 - 0.017 14.0 0.0 0.048 12.6 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 OEU14889.1 - 0.081 11.9 0.0 0.21 10.6 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase CARD_2 PF16739.5 OEU14889.1 - 0.096 12.7 0.1 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Caspase recruitment domain DUF562 PF04763.12 OEU14889.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF562) Dehydrin PF00257.19 OEU14890.1 - 0.015 15.9 1.9 0.041 14.4 1.9 1.7 1 0 0 1 1 1 0 Dehydrin UPF0524 PF15823.5 OEU14890.1 - 0.077 12.4 1.9 0.093 12.1 0.0 2.0 3 0 0 3 3 3 0 UPF0524 of C3orf70 Coatomer_WDAD PF04053.14 OEU14893.1 - 0.0057 15.8 0.0 1.2 8.1 0.0 3.1 3 0 0 3 3 3 2 Coatomer WD associated region Ammonium_transp PF00909.21 OEU14894.1 - 7.1e-104 347.7 18.8 8.9e-104 347.3 18.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sel1 PF08238.12 OEU14897.1 - 0.00066 20.3 0.0 1.5 9.6 0.0 2.6 2 0 0 2 2 2 2 Sel1 repeat RNase_H2_suC PF08615.11 OEU14898.1 - 0.0068 16.6 3.6 0.0068 16.6 3.6 2.4 2 1 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HA PF03457.14 OEU14899.1 - 8.3e-36 122.1 10.5 2.4e-15 56.6 0.1 3.1 3 0 0 3 3 3 3 Helicase associated domain ELL PF10390.9 OEU14899.1 - 7.7e-05 22.3 0.1 0.047 13.2 0.0 2.8 2 1 1 3 3 3 2 RNA polymerase II elongation factor ELL DUF3836 PF12930.7 OEU14899.1 - 0.0024 17.6 1.4 1.5 8.6 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF3836) Phosphoesterase PF04185.14 OEU14899.1 - 0.044 13.0 0.9 0.58 9.3 0.1 2.0 1 1 1 2 2 2 0 Phosphoesterase family GA-like PF17573.2 OEU14899.1 - 0.086 12.8 0.5 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 GA-like domain WD40_alt PF14077.6 OEU14900.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif RVT_1 PF00078.27 OEU14901.1 - 1.5e-06 27.9 0.0 6.2e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU14901.1 - 6.2e-05 23.6 0.4 6.2e-05 23.6 0.4 3.1 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase HDC PF02329.16 OEU14901.1 - 0.037 13.0 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine carboxylase PI chain zf-RVT PF13966.6 OEU14903.1 - 0.0076 16.9 0.7 0.034 14.9 0.7 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Mei5_like PF17021.5 OEU14903.1 - 0.14 12.2 0.3 0.14 12.2 0.3 3.8 3 1 1 4 4 4 0 Putative double-strand recombination repair-like DUF4407 PF14362.6 OEU14903.1 - 0.25 10.7 3.1 2.9 7.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5097 PF17020.5 OEU14904.1 - 0.041 14.2 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) DUF3295 PF11702.8 OEU14905.1 - 3.7 6.8 9.6 4.6 6.5 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF1117 PF06547.12 OEU14906.1 - 0.075 13.6 1.3 0.092 13.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) BTB PF00651.31 OEU14908.1 - 8.6e-15 54.9 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 OEU14908.1 - 0.023 14.9 0.1 3.5 7.8 0.2 2.6 1 1 1 2 2 2 0 MATH domain BACK PF07707.15 OEU14908.1 - 0.024 14.8 0.1 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch TbpB_C PF17483.2 OEU14909.1 - 0.049 14.0 0.5 0.086 13.2 0.5 1.3 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B gag-asp_proteas PF13975.6 OEU14910.1 - 4.4e-10 40.0 5.9 6.3e-05 23.5 0.4 5.3 4 1 2 6 6 6 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OEU14910.1 - 6.4e-10 39.5 3.9 2.8e-05 24.7 0.1 4.1 4 1 1 5 5 5 2 Aspartyl protease RVP PF00077.20 OEU14910.1 - 0.0075 16.6 0.1 0.036 14.4 0.1 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 OEU14910.1 - 0.11 12.3 0.0 0.5 10.2 0.0 2.0 3 0 0 3 3 3 0 Aspartyl protease BTB PF00651.31 OEU14911.1 - 4.4e-16 59.1 0.5 3.2e-15 56.3 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain DUF4788 PF16032.5 OEU14911.1 - 0.008 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4788) SAP PF02037.27 OEU14911.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.3 3 0 0 3 3 3 0 SAP domain HA2 PF04408.23 OEU14914.1 - 3.9e-18 65.7 0.0 9.1e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OEU14914.1 - 2e-15 57.1 0.1 6.9e-15 55.4 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OEU14914.1 - 1.1e-12 48.1 0.0 2.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OEU14914.1 - 7.4e-12 45.4 2.0 7.4e-12 45.4 2.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OEU14914.1 - 8.3e-06 26.1 0.8 8.3e-06 26.1 0.8 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OEU14914.1 - 0.00021 21.6 3.9 0.00049 20.5 1.0 2.8 3 0 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.14 OEU14914.1 - 0.001 19.0 0.5 0.0027 17.7 0.5 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 OEU14914.1 - 0.0015 18.6 0.1 0.0036 17.3 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OEU14914.1 - 0.0041 16.9 1.2 0.0055 16.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OEU14914.1 - 0.018 14.6 0.2 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytochrom_C PF00034.21 OEU14916.1 - 1e-11 45.8 0.1 1.4e-11 45.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OEU14916.1 - 1.1e-06 28.8 2.0 7.7e-06 26.1 2.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OEU14916.1 - 0.0045 16.7 0.3 0.016 14.9 0.2 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Neur_chan_LBD PF02931.23 OEU14920.1 - 3e-23 82.4 0.1 4.8e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain KSHV_K1 PF11049.8 OEU14922.1 - 0.24 11.4 7.0 1.4 8.9 0.1 3.4 4 0 0 4 4 4 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus GTPase_binding PF09027.10 OEU14922.1 - 3.6 7.6 7.0 5.6 7.0 1.7 3.2 4 0 0 4 4 4 0 GTPase binding His_Phos_1 PF00300.22 OEU14923.1 - 0.00036 20.3 0.0 5.1 6.7 0.0 3.6 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) CENP-B_dimeris PF09026.10 OEU14923.1 - 0.13 12.7 12.7 0.55 10.6 0.1 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 OEU14923.1 - 6.8 7.0 13.0 4.7 7.5 1.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Serglycin PF04360.12 OEU14924.1 - 0.32 10.9 7.1 0.075 13.0 3.4 1.8 2 0 0 2 2 2 0 Serglycin PP2C PF00481.21 OEU14926.1 - 2.4e-39 135.5 0.0 5.4e-39 134.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU14926.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C Pkinase PF00069.25 OEU14927.1 - 1e-10 41.4 0.0 1.6e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Methyltransf_16 PF10294.9 OEU14929.1 - 1.1e-19 70.8 0.1 6.7e-11 42.2 0.0 2.5 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 OEU14929.1 - 4e-06 26.8 0.1 2e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MMR1 PF08505.10 OEU14929.1 - 0.0019 18.6 2.8 0.0019 18.6 2.8 1.7 2 0 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein Methyltransf_12 PF08242.12 OEU14929.1 - 0.0023 18.6 2.0 0.4 11.5 0.1 2.5 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU14929.1 - 0.01 15.6 2.9 0.42 10.4 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain SR-25 PF10500.9 OEU14929.1 - 0.014 15.0 1.7 0.014 15.0 1.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lep_receptor_Ig PF06328.11 OEU14929.1 - 0.03 14.3 2.6 0.07 13.1 2.6 1.7 1 0 0 1 1 1 0 Ig-like C2-type domain DUF2859 PF11072.8 OEU14929.1 - 0.051 13.3 0.3 0.3 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) GFP PF01353.22 OEU14929.1 - 0.062 12.8 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein Spt20 PF12090.8 OEU14929.1 - 0.064 12.9 14.9 0.1 12.2 14.9 1.3 1 0 0 1 1 1 0 Spt20 family CLN3 PF02487.17 OEU14929.1 - 0.13 11.3 5.2 0.24 10.4 5.2 1.3 1 1 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 OEU14929.1 - 0.16 10.7 0.8 0.18 10.5 0.8 1.2 1 0 0 1 1 1 0 Presenilin DUF755 PF05501.11 OEU14929.1 - 2.6 8.3 27.2 0.41 10.9 14.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4050 PF13259.6 OEU14929.1 - 7.6 6.8 11.1 10 6.4 11.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) ARD PF03079.14 OEU14931.1 - 1.6e-41 142.1 1.7 9.2e-41 139.6 0.1 2.4 2 1 0 2 2 2 1 ARD/ARD' family AraC_binding PF02311.19 OEU14931.1 - 9.8e-08 32.0 0.1 1.4e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 OEU14931.1 - 1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OEU14931.1 - 1.2e-05 24.9 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Glyco_transf_11 PF01531.16 OEU14931.1 - 0.0037 16.5 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 Kri1 PF05178.12 OEU14931.1 - 0.3 11.7 4.5 0.66 10.6 1.6 2.2 2 0 0 2 2 2 0 KRI1-like family COX15-CtaA PF02628.15 OEU14934.1 - 0.025 13.6 0.1 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Yae1_N PF09811.9 OEU14935.1 - 1.3e-08 34.3 54.4 1.5 8.6 0.7 13.9 3 2 9 12 12 12 8 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU14935.1 - 0.2 11.7 40.9 0.051 13.6 11.1 6.6 3 1 3 6 6 6 0 Glycine zipper MtrG PF04210.13 OEU14935.1 - 2.2 8.2 23.7 4.8 7.1 0.1 7.7 3 3 5 8 8 8 0 Tetrahydromethanopterin S-methyltransferase, subunit G Drf_FH1 PF06346.12 OEU14937.1 - 0.003 17.3 42.0 0.003 17.3 42.0 2.1 1 1 1 2 2 2 1 Formin Homology Region 1 PT PF04886.12 OEU14938.1 - 4.4e-05 22.9 39.1 0.072 12.6 7.8 5.0 1 1 3 4 4 4 3 PT repeat LCIB_C_CA PF18599.1 OEU14939.1 - 1.6e-62 210.7 0.0 1.9e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Trypsin PF00089.26 OEU14941.1 - 1.7e-31 109.7 0.2 7.5e-31 107.7 0.2 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU14941.1 - 0.041 14.8 0.0 0.087 13.7 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain FAM176 PF14851.6 OEU14941.1 - 4.5 6.9 7.5 0.7 9.6 0.3 2.6 3 0 0 3 3 3 0 FAM176 family Mucin PF01456.17 OEU14941.1 - 9.2 6.3 10.0 25 4.8 10.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Dapper PF15268.6 OEU14942.1 - 0.41 9.5 24.2 0.48 9.2 24.2 1.2 1 0 0 1 1 1 0 Dapper V_ATPase_I PF01496.19 OEU14942.1 - 2.9 5.7 17.8 3.6 5.4 17.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PNISR PF15996.5 OEU14942.1 - 9.1 6.5 30.7 0.33 11.2 12.3 2.1 1 1 1 2 2 2 0 Arginine/serine-rich protein PNISR E1-E2_ATPase PF00122.20 OEU14943.1 - 1.1e-45 155.4 0.0 2.9e-45 154.0 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OEU14943.1 - 3.8e-38 131.0 3.5 1.2e-37 129.4 3.5 2.0 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OEU14943.1 - 8e-17 62.2 0.6 2.2e-15 57.5 0.6 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU14943.1 - 5.6e-12 45.6 0.4 5.6e-12 45.6 0.4 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OEU14943.1 - 7.5e-11 41.6 0.0 2.4e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OEU14943.1 - 1.7e-05 24.7 1.2 1.7e-05 24.7 1.2 3.5 3 1 0 4 4 4 1 haloacid dehalogenase-like hydrolase Mucin PF01456.17 OEU14943.1 - 4.7 7.2 8.2 18 5.3 1.0 3.1 3 0 0 3 3 3 0 Mucin-like glycoprotein TauE PF01925.19 OEU14944.1 - 3.3e-18 66.2 5.8 3.3e-18 66.2 5.8 2.4 3 0 0 3 3 3 1 Sulfite exporter TauE/SafE OFeT_1 PF16955.5 OEU14944.1 - 0.018 14.8 0.8 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron uptake permease, iron-lead transporter NYN_YacP PF05991.11 OEU14947.1 - 1.2e-28 100.1 0.0 2e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 YacP-like NYN domain BAT2_N PF07001.11 OEU14947.1 - 0.063 13.7 6.3 0.12 12.8 6.3 1.4 1 0 0 1 1 1 0 BAT2 N-terminus MccV PF17508.2 OEU14947.1 - 0.38 11.3 0.2 0.38 11.3 0.2 1.9 2 0 0 2 2 2 0 Microcin V bacteriocin HA PF03457.14 OEU14948.1 - 3.2e-17 62.6 2.7 6.8e-12 45.5 0.2 2.1 2 0 0 2 2 2 2 Helicase associated domain Tudor-knot PF11717.8 OEU14948.1 - 0.018 14.9 1.0 1.8 8.5 0.3 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Peptidase_M16 PF00675.20 OEU14950.1 - 1.5e-51 174.3 0.4 2.9e-51 173.4 0.4 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU14950.1 - 2.3e-32 112.5 0.1 2.4e-30 105.9 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain PI_PP_C PF18365.1 OEU14950.1 - 0.029 14.3 0.0 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Ank_2 PF12796.7 OEU14952.1 - 1.7e-17 63.7 0.0 7.7e-12 45.6 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU14952.1 - 8.8e-13 48.5 0.1 1.5e-05 25.4 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU14952.1 - 5.9e-10 39.1 0.2 0.0016 18.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OEU14952.1 - 3.2e-08 33.7 0.5 0.13 12.7 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU14952.1 - 9.9e-08 31.7 0.8 0.0031 17.9 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat DCB PF16213.5 OEU14952.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 LPG_synthase_TM PF03706.13 OEU14953.1 - 0.076 12.5 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SOG2 PF10428.9 OEU14953.1 - 4.3 6.4 18.2 5.2 6.2 18.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein EF-hand_1 PF00036.32 OEU14954.1 - 0.015 14.8 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 OEU14954.1 - 0.029 13.9 0.2 0.079 12.5 0.2 1.7 1 0 0 1 1 1 0 EF hand Myc_N PF01056.18 OEU14954.1 - 0.047 13.6 0.4 0.047 13.6 0.4 1.6 2 0 0 2 2 2 0 Myc amino-terminal region EF-hand_6 PF13405.6 OEU14954.1 - 0.074 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DUF2807 PF10988.8 OEU14954.1 - 0.58 9.9 10.6 0.23 11.2 8.0 1.7 2 0 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain PRR18 PF15671.5 OEU14954.1 - 4.7 7.0 13.9 0.94 9.3 10.5 1.5 2 0 0 2 2 2 0 Proline-rich protein family 18 Herpes_gE PF02480.16 OEU14957.1 - 0.0016 17.3 0.1 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 OEU14957.1 - 0.0026 17.7 2.1 0.0026 17.7 2.1 1.7 2 0 0 2 2 2 1 TMEM154 protein family PTP_tm PF18861.1 OEU14957.1 - 0.057 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MFS_1 PF07690.16 OEU14959.1 - 2.4e-13 49.7 35.7 2.4e-13 49.7 35.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TssO PF17561.2 OEU14959.1 - 5.3 7.1 9.1 18 5.4 0.4 3.7 4 0 0 4 4 4 0 Type VI secretion system, TssO SUIM_assoc PF16619.5 OEU14960.1 - 0.12 12.4 1.4 0.36 10.9 1.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FAD_binding_4 PF01565.23 OEU14961.1 - 2.2e-14 53.4 2.8 1.4e-13 50.8 0.4 3.1 2 1 0 2 2 2 1 FAD binding domain zf-MYND PF01753.18 OEU14963.1 - 6.3e-05 23.0 7.6 8.4e-05 22.6 6.2 1.9 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 OEU14963.1 - 0.27 11.1 6.3 0.96 9.4 6.3 1.9 1 1 0 1 1 1 0 HIT zinc finger DUF2256 PF10013.9 OEU14963.1 - 6.5 7.0 9.9 6.6 6.9 8.2 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF5351 PF17302.2 OEU14964.1 - 1.4 9.2 6.1 2.4 8.4 6.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5351) Forkhead PF00250.18 OEU14967.1 - 0.042 14.1 0.1 0.21 11.9 0.1 2.2 1 0 0 1 1 1 0 Forkhead domain AAA PF00004.29 OEU14968.1 - 1.6e-89 297.2 0.0 5.5e-46 156.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU14968.1 - 6.2e-25 86.7 6.5 5.2e-12 45.4 0.1 3.5 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 OEU14968.1 - 1.2e-14 54.8 0.0 1e-08 35.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OEU14968.1 - 1.3e-13 51.7 1.5 1.3e-05 25.7 0.0 4.0 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 OEU14968.1 - 2.2e-13 50.4 0.0 4e-08 33.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU14968.1 - 3.1e-12 46.5 0.0 3e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 OEU14968.1 - 2.5e-10 40.4 0.2 9.2e-10 38.6 0.1 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 OEU14968.1 - 8.9e-10 38.9 0.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 OEU14968.1 - 9.1e-10 38.3 0.0 0.0002 20.7 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OEU14968.1 - 6.8e-09 36.1 0.6 0.055 13.7 0.1 4.1 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 OEU14968.1 - 6.1e-08 32.8 0.0 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OEU14968.1 - 1.7e-07 31.8 0.0 0.017 15.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OEU14968.1 - 4.4e-07 30.5 0.7 0.0073 16.8 0.0 3.5 3 1 0 3 3 2 2 ABC transporter RNA_helicase PF00910.22 OEU14968.1 - 5.8e-07 29.9 0.0 0.013 15.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.26 OEU14968.1 - 9.5e-07 28.7 0.0 0.0037 17.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OEU14968.1 - 9.8e-07 28.7 0.0 0.034 13.9 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 OEU14968.1 - 1.2e-06 28.4 0.2 0.03 14.1 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 OEU14968.1 - 1.2e-06 28.5 0.1 0.079 12.9 0.0 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_28 PF13521.6 OEU14968.1 - 3e-06 27.6 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OEU14968.1 - 3.2e-06 27.2 0.1 0.34 10.8 0.0 3.6 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea ATPase PF06745.13 OEU14968.1 - 6.6e-06 25.6 0.5 0.038 13.3 0.2 3.4 2 1 0 2 2 2 1 KaiC TsaE PF02367.17 OEU14968.1 - 8.5e-06 25.8 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OEU14968.1 - 1.6e-05 24.4 1.9 0.011 15.1 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OEU14968.1 - 2.3e-05 24.0 0.1 0.29 10.6 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 OEU14968.1 - 2.9e-05 23.7 2.2 1.4 8.5 0.0 3.6 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 OEU14968.1 - 2.9e-05 24.1 0.3 0.3 11.0 0.0 3.1 3 1 0 3 3 3 2 NACHT domain CDC48_2 PF02933.17 OEU14968.1 - 0.0001 22.0 0.0 0.00035 20.3 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.12 OEU14968.1 - 0.00019 20.7 0.0 0.39 10.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 OEU14968.1 - 0.00022 21.0 0.0 1 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.6 OEU14968.1 - 0.00028 21.3 1.1 0.11 12.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 OEU14968.1 - 0.00054 19.5 0.2 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.10 OEU14968.1 - 0.00074 19.5 0.2 0.0029 17.6 0.2 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 OEU14968.1 - 0.00091 19.4 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 OEU14968.1 - 0.001 19.2 0.1 1.5 8.9 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.17 OEU14968.1 - 0.0012 18.0 0.3 0.072 12.2 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OEU14968.1 - 0.0012 18.0 0.0 0.86 8.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 OEU14968.1 - 0.0015 17.8 0.0 0.42 9.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.9 OEU14968.1 - 0.0015 18.3 0.1 3.3 7.5 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 OEU14968.1 - 0.0035 17.9 1.7 4.3 7.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 OEU14968.1 - 0.0056 16.4 0.0 0.72 9.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SKI PF01202.22 OEU14968.1 - 0.0087 16.2 0.0 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase TMEM156 PF15106.6 OEU14968.1 - 0.0091 15.5 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 TMEM156 protein family Cytidylate_kin PF02224.18 OEU14968.1 - 0.018 14.8 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_3 PF07726.11 OEU14968.1 - 0.019 14.9 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OEU14968.1 - 0.019 14.8 0.0 1.4 8.7 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein Molydop_binding PF01568.21 OEU14968.1 - 0.026 14.5 0.2 3.3 7.8 0.0 2.6 1 1 1 2 2 2 0 Molydopterin dinucleotide binding domain DUF1967 PF09269.11 OEU14968.1 - 0.032 14.2 0.1 17 5.4 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF1967) IPT PF01745.16 OEU14968.1 - 0.045 13.2 0.3 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 OEU14968.1 - 0.062 13.0 0.3 8.1 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OEU14968.1 - 0.064 13.2 0.0 4.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OEU14968.1 - 0.069 12.9 2.3 5.1 6.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 OEU14968.1 - 0.075 12.9 1.5 7.8 6.4 0.0 3.5 3 1 1 4 4 3 0 NTPase AAA_6 PF12774.7 OEU14968.1 - 0.17 10.8 0.1 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Enolase_like_N PF18374.1 OEU14968.1 - 0.18 11.2 0.9 15 5.1 0.0 3.4 4 0 0 4 4 3 0 Enolase N-terminal domain-like AAA_19 PF13245.6 OEU14968.1 - 1 9.7 4.4 24 5.3 0.0 3.2 3 1 0 4 4 2 0 AAA domain DUF1754 PF08555.10 OEU14968.1 - 3.1 8.7 17.2 2.1 9.2 5.2 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Rtf2 PF04641.12 OEU14968.1 - 6.4 6.1 10.7 4.6 6.5 0.9 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Aminotran_3 PF00202.21 OEU14969.1 - 6.7e-74 249.0 0.0 8.1e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OEU14969.1 - 0.0075 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DHQ_synthase PF01761.20 OEU14970.1 - 3e-105 351.1 0.0 3.9e-105 350.7 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OEU14970.1 - 1.2e-11 44.8 0.2 8.5e-11 42.0 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 OEU14970.1 - 6.7e-09 35.0 0.5 1.6e-08 33.8 0.5 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase UbiA PF01040.18 OEU14971.1 - 1.5e-33 116.1 15.3 3.1e-33 115.1 15.3 1.6 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF5305 PF17231.2 OEU14971.1 - 0.083 12.3 5.6 0.22 10.9 5.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BNIP2 PF12496.8 OEU14971.1 - 0.11 12.9 1.9 0.21 12.0 1.9 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 URO-D PF01208.17 OEU14972.1 - 1.5e-97 326.9 0.0 1.9e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pheromone PF08015.11 OEU14972.1 - 2.8 9.1 4.5 2 9.5 2.1 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone NUDIX PF00293.28 OEU14973.1 - 3.9e-21 75.5 0.0 7.1e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain SQS_PSY PF00494.19 OEU14974.1 - 1.2e-30 106.9 0.0 1.7e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Coprogen_oxidas PF01218.18 OEU14975.1 - 5e-96 320.9 0.0 6e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PEPcase PF00311.17 OEU14976.1 - 2.7e-260 865.8 0.6 3.2e-260 865.6 0.6 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 OEU14976.1 - 0.00013 20.7 0.0 0.00021 19.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Adenylate_cycl PF01295.18 OEU14976.1 - 0.019 13.6 0.1 0.032 12.9 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I Glyco_hydro_16 PF00722.21 OEU14977.1 - 1.1e-17 64.0 4.2 1.5e-17 63.7 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 OEU14977.1 - 9.3e-07 29.1 4.5 1.2e-06 28.8 4.5 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) SKN1 PF03935.15 OEU14977.1 - 0.00045 18.8 1.1 0.59 8.5 0.2 2.7 3 0 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 OEU14978.1 - 2.4e-10 40.2 0.2 5.6e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FA_desaturase PF00487.24 OEU14979.1 - 1.8e-32 113.2 20.3 3.1e-32 112.4 20.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OEU14979.1 - 2.3e-09 37.3 0.0 4.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_1 PF00441.24 OEU14980.1 - 2.2e-46 157.8 3.9 5.5e-46 156.5 3.7 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OEU14980.1 - 4e-31 108.0 0.1 1.7e-30 106.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OEU14980.1 - 1.3e-27 95.9 0.1 2.3e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OEU14980.1 - 1.1e-19 71.0 2.2 1.8e-19 70.4 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OEU14980.1 - 0.0077 15.9 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 OEU14981.1 - 2.1e-36 125.4 0.2 3.3e-36 124.8 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OEU14981.1 - 4.9e-19 69.1 0.0 1.4e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OEU14981.1 - 9.4e-19 67.4 0.1 2e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OEU14981.1 - 7.9e-16 58.5 0.0 1.4e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CAP_N PF01213.19 OEU14981.1 - 0.2 11.1 1.6 0.37 10.2 1.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pheromone PF08015.11 OEU14981.1 - 5.5 8.1 13.5 0.84 10.7 5.5 3.1 3 1 0 3 3 3 0 Fungal mating-type pheromone Mito_fiss_reg PF05308.11 OEU14981.1 - 7.1 6.6 7.4 0.93 9.5 2.7 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Epimerase PF01370.21 OEU14982.1 - 1.2e-15 57.7 0.0 4.4e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU14982.1 - 2.3e-08 33.8 0.0 0.00016 21.2 0.0 3.5 2 2 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OEU14982.1 - 0.035 13.3 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 OEU14982.1 - 0.069 12.3 0.0 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OEU14982.1 - 0.13 11.2 0.1 0.87 8.5 0.0 2.4 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF908 PF06012.12 OEU14982.1 - 0.27 10.6 4.5 0.49 9.7 4.1 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF3494 PF11999.8 OEU14983.1 - 1.1e-52 178.7 13.5 1.1e-52 178.7 13.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU14984.1 - 9.7e-47 159.3 8.8 1.2e-46 159.0 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Bactofilin PF04519.13 OEU14984.1 - 0.079 13.3 0.2 0.079 13.3 0.2 2.7 3 1 0 3 3 3 0 Polymer-forming cytoskeletal DUF3494 PF11999.8 OEU14985.1 - 2.1e-51 174.6 21.6 2.1e-51 174.6 21.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) NADH-u_ox-rdase PF10785.9 OEU14985.1 - 0.18 12.5 0.5 4.5 8.0 0.2 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4200 PF13863.6 OEU14986.1 - 0.041 14.3 0.1 0.081 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Brix PF04427.18 OEU14988.1 - 2e-36 125.9 0.0 2.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain HMG_box PF00505.19 OEU14990.1 - 3.5e-16 59.4 0.0 1e-15 57.9 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU14990.1 - 3.3e-11 43.6 2.4 3.8e-11 43.4 0.0 2.4 2 1 0 2 2 2 1 HMG-box domain NINJA_B PF16136.5 OEU14990.1 - 0.032 14.6 0.4 0.032 14.6 0.4 3.8 3 1 1 4 4 4 0 Putative nuclear localisation signal DUF1013 PF06242.11 OEU14990.1 - 0.9 9.6 8.0 0.095 12.7 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) NDK PF00334.19 OEU14991.1 - 1e-07 32.1 0.0 0.00047 20.2 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Pkinase PF00069.25 OEU14992.1 - 1.2e-41 142.8 0.0 3.2e-39 134.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU14992.1 - 2.4e-16 59.8 0.0 2.2e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU14992.1 - 0.0026 17.7 0.0 0.0065 16.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DTC PF18102.1 OEU14993.1 - 5.5e-39 133.4 0.0 8.8e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_2 PF13639.6 OEU14993.1 - 9.2e-10 38.7 10.4 1.8e-09 37.8 10.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU14993.1 - 3.3e-07 30.0 14.2 2e-06 27.6 14.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU14993.1 - 3.9e-07 29.8 11.1 7.4e-07 28.9 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU14993.1 - 3.2e-06 27.0 5.5 8.4e-06 25.7 5.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OEU14993.1 - 8.6e-05 22.2 7.6 0.00032 20.4 7.6 2.0 1 1 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU14993.1 - 0.00014 22.1 15.0 0.00028 21.1 13.0 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OEU14993.1 - 0.0006 19.6 11.0 0.0014 18.4 11.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU14993.1 - 0.0015 18.5 7.6 0.0095 16.0 7.6 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OEU14993.1 - 0.0059 16.4 11.5 0.041 13.7 11.5 2.2 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OEU14993.1 - 0.0099 15.7 11.5 0.04 13.8 5.5 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 OEU14993.1 - 0.025 14.8 6.2 0.076 13.2 6.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU14993.1 - 0.031 14.2 13.1 0.12 12.3 13.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 OEU14993.1 - 0.049 13.4 9.2 0.16 11.8 9.2 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.11 OEU14993.1 - 0.057 13.4 1.2 0.088 12.8 1.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 OEU14993.1 - 0.089 12.4 10.2 0.95 9.1 10.2 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OEU14993.1 - 0.9 9.9 14.0 0.16 12.3 8.5 2.4 3 0 0 3 3 2 0 RING-like domain zf-C3HC4_4 PF15227.6 OEU14993.1 - 2 8.6 10.5 15 5.8 0.2 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_9 PF13901.6 OEU14993.1 - 2 8.3 11.4 8.6 6.3 11.7 1.7 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Methyltransf_16 PF10294.9 OEU14994.1 - 6.7e-22 78.0 0.0 4.6e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 OEU14994.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OEU14994.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF4342 PF14242.6 OEU14994.1 - 0.19 11.7 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) GARS_A PF01071.19 OEU14995.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TFIIA PF03153.13 OEU14995.1 - 0.08 12.9 7.7 0.095 12.7 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 OEU14995.1 - 0.13 10.2 19.4 0.19 9.6 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4810 PF16068.5 OEU14995.1 - 0.31 11.6 6.4 0.56 10.8 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) PPR_2 PF13041.6 OEU14996.1 - 8.2e-10 38.7 0.1 3.4e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 OEU14996.1 - 1.8e-07 30.9 0.1 0.074 13.3 0.0 3.4 3 0 0 3 3 3 3 PPR repeat PPR_long PF17177.4 OEU14996.1 - 0.00038 19.9 0.3 0.0016 17.8 0.0 1.9 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP RPN7 PF10602.9 OEU14996.1 - 0.00053 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PPR_1 PF12854.7 OEU14996.1 - 0.00097 18.8 0.4 14 5.5 0.0 3.3 3 0 0 3 3 3 2 PPR repeat Peptidase_M99_C PF17129.4 OEU14996.1 - 0.023 14.9 0.6 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain of metallo-carboxypeptidase Secretin_N_2 PF07655.13 OEU14996.1 - 0.22 12.1 8.2 2.8 8.5 1.8 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CENP-B_dimeris PF09026.10 OEU14996.1 - 6.6 7.2 9.6 1.5 9.3 0.9 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain TFB6 PF17110.5 OEU14996.1 - 9.4 5.9 8.4 0.9 9.3 1.3 2.2 1 1 1 2 2 2 0 Subunit 11 of the general transcription factor TFIIH PRORP PF16953.5 OEU14997.1 - 6.2e-08 32.5 0.7 0.00014 21.5 0.1 2.2 2 0 0 2 2 2 2 Protein-only RNase P PRORP PF16953.5 OEU14998.1 - 8.2e-07 28.8 1.4 0.0027 17.3 0.3 2.6 2 2 0 2 2 2 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 OEU14998.1 - 0.0026 17.6 0.1 0.098 12.4 0.0 2.2 2 0 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain ThiF PF00899.21 OEU14999.1 - 1.1e-62 211.6 0.0 1.6e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OEU14999.1 - 1.7e-25 89.0 0.3 3.2e-25 88.1 0.3 1.5 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OEU14999.1 - 0.056 13.5 0.5 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 OEU14999.1 - 0.1 12.8 3.7 0.28 11.4 0.8 2.3 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein HTH_Tnp_1 PF01527.20 OEU15000.1 - 6.2e-07 29.6 1.8 1e-06 28.9 0.2 2.2 2 0 0 2 2 2 1 Transposase DUF2732 PF10809.8 OEU15000.1 - 0.0081 16.0 0.6 0.022 14.6 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2732) MPM1 PF17234.2 OEU15000.1 - 2.4 8.4 19.8 3.3 8.0 11.1 2.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PAS PF00989.25 OEU15000.1 - 4.1 7.4 5.8 11 6.1 1.2 2.7 2 0 0 2 2 2 0 PAS fold HSF_DNA-bind PF00447.17 OEU15001.1 - 1.7e-22 79.9 0.1 1.8e-22 79.7 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Proteasome_A_N PF10584.9 OEU15001.1 - 0.021 14.5 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Ebola_NP PF05505.12 OEU15001.1 - 0.13 10.6 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3984 PF13136.6 OEU15002.1 - 0.026 14.0 2.9 0.033 13.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF2244 PF10003.9 OEU15002.1 - 1 9.0 4.8 1.6 8.4 4.8 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Myb_DNA-binding PF00249.31 OEU15003.1 - 9.9e-25 86.5 0.1 3.2e-13 49.7 0.1 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU15003.1 - 2.2e-21 75.9 0.1 4.8e-15 55.5 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU15003.1 - 5.4e-07 29.4 0.0 0.00016 21.5 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OEU15003.1 - 0.001 19.4 0.6 0.94 9.9 0.2 3.0 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OEU15003.1 - 0.024 14.8 0.0 1.7 8.9 0.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OEU15003.1 - 0.032 14.4 0.2 0.44 10.8 0.0 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Na_H_Exchanger PF00999.21 OEU15005.1 - 9.5e-62 209.0 39.1 1.2e-61 208.6 39.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 OEU15005.1 - 0.0013 18.5 24.7 0.0084 15.9 7.1 2.8 2 1 1 3 3 3 2 Predicted Permease Membrane Region zf-met2 PF12907.7 OEU15006.1 - 1.5e-06 28.2 2.0 2.4e-06 27.6 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding Abhydrolase_6 PF12697.7 OEU15007.1 - 2.9e-18 67.3 0.0 3.9e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU15007.1 - 8.3e-16 58.4 0.0 1.2e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OEU15007.1 - 9.9e-09 35.1 0.0 4.3e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 OEU15007.1 - 4.5e-08 32.7 0.1 7.4e-05 22.1 0.1 3.1 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 OEU15007.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OEU15007.1 - 0.0041 17.0 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OEU15007.1 - 0.011 15.6 0.0 0.46 10.4 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 OEU15007.1 - 0.016 14.7 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase PF00151.19 OEU15007.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase Ser_hydrolase PF06821.13 OEU15007.1 - 0.035 13.9 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase UPF0227 PF05728.12 OEU15007.1 - 0.038 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-MYND PF01753.18 OEU15008.1 - 9.9e-16 57.6 36.8 8.7e-09 35.3 17.3 2.7 2 0 0 2 2 2 2 MYND finger TPR_12 PF13424.6 OEU15008.1 - 0.0016 18.7 0.2 0.0034 17.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15008.1 - 0.1 12.5 6.6 0.11 12.3 1.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_His PF13393.6 OEU15008.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase MIT PF04212.18 OEU15008.1 - 0.22 11.6 5.4 3.1 7.9 0.1 2.8 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OEU15008.1 - 0.28 11.4 4.5 8.6 6.7 1.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15008.1 - 1.1 9.7 6.0 3.7 8.0 0.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 OEU15009.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like Peptidase_M50B PF13398.6 OEU15010.1 - 5.1e-43 147.0 14.5 6.6e-43 146.7 14.5 1.1 1 0 0 1 1 1 1 Peptidase M50B-like COX14 PF14880.6 OEU15010.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.9 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF4604 PF15377.6 OEU15011.1 - 0.002 18.6 0.3 0.002 18.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) E7 PF00527.18 OEU15011.1 - 0.034 14.3 0.9 0.054 13.7 0.9 1.3 1 0 0 1 1 1 0 E7 protein, Early protein LpxB PF02684.15 OEU15011.1 - 0.049 12.5 0.1 0.057 12.2 0.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Myc_N PF01056.18 OEU15011.1 - 0.051 13.5 2.0 0.057 13.3 2.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF4202 PF13875.6 OEU15011.1 - 0.056 13.3 1.8 0.071 13.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) FAM176 PF14851.6 OEU15011.1 - 0.075 12.7 5.0 0.089 12.5 5.0 1.2 1 0 0 1 1 1 0 FAM176 family SET PF00856.28 OEU15012.1 - 6.8e-08 33.1 0.0 2.1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 SET domain Cyclin_N PF00134.23 OEU15013.1 - 3.2e-34 117.4 0.3 7.5e-34 116.2 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU15013.1 - 4.2e-25 88.2 0.3 3.2e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 OEU15013.1 - 0.034 14.2 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Aldo_ket_red PF00248.21 OEU15014.1 - 1e-49 169.3 0.0 1.2e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 OEU15015.1 - 9e-53 176.2 2.3 2.2e-20 72.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M48_N PF16491.5 OEU15016.1 - 2.6e-64 216.5 0.6 6.2e-64 215.2 0.6 1.6 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OEU15016.1 - 9e-43 146.3 0.0 1.4e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Sec62 PF03839.16 OEU15016.1 - 0.044 13.3 1.1 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Vfa1 PF08432.10 OEU15016.1 - 0.095 13.0 8.1 0.17 12.2 8.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_M56 PF05569.11 OEU15016.1 - 0.12 11.5 0.1 0.31 10.2 0.1 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 CPSF100_C PF13299.6 OEU15016.1 - 0.18 11.9 2.1 0.29 11.3 2.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal YchF-GTPase_C PF06071.13 OEU15017.1 - 2e-35 120.8 0.1 3.8e-35 119.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OEU15017.1 - 2.7e-21 75.8 0.0 4.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU15017.1 - 8.8e-06 25.3 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU15017.1 - 0.04 14.0 0.0 1.1 9.2 0.0 2.4 1 1 0 2 2 2 0 Dynamin family MeaB PF03308.16 OEU15017.1 - 0.052 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 OEU15017.1 - 0.15 12.5 0.0 0.91 10.0 0.0 2.0 1 1 0 1 1 1 0 ABC transporter Ribonuclease_3 PF00636.26 OEU15018.1 - 1.4e-11 44.9 0.0 1.6e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease III domain His_Phos_1 PF00300.22 OEU15020.1 - 9.3e-06 25.5 0.0 0.46 10.1 0.0 3.3 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) PUNUT PF16913.5 OEU15021.1 - 0.094 11.9 14.7 0.042 13.1 11.8 1.7 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Fer4_19 PF06902.11 OEU15022.1 - 0.01 15.9 0.5 21 5.3 0.1 4.4 3 1 0 3 3 3 0 Divergent 4Fe-4S mono-cluster KCT2 PF17818.1 OEU15024.1 - 0.0015 18.7 0.1 0.0015 18.7 0.1 2.0 1 1 1 2 2 2 1 Keratinocyte-associated gene product GH101_N PF17995.1 OEU15024.1 - 0.02 14.5 4.5 0.043 13.5 4.5 1.6 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal SDA1 PF05285.12 OEU15024.1 - 3.8 6.8 9.5 4.5 6.6 9.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OEU15024.1 - 7.3 5.8 10.9 8.5 5.6 10.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OEU15024.1 - 8.5 4.4 8.0 9.5 4.3 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family EMP24_GP25L PF01105.24 OEU15025.1 - 1.7e-14 54.2 0.2 2.2e-14 53.8 0.2 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 60KD_IMP PF02096.20 OEU15025.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein CLZ PF16526.5 OEU15025.1 - 0.44 10.9 8.0 0.086 13.2 2.8 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3024 PF11225.8 OEU15027.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) PqiA PF04403.13 OEU15028.1 - 1.9e-15 57.0 18.1 3.2e-10 40.0 3.6 3.0 3 0 0 3 3 3 2 Paraquat-inducible protein A Herpes_gE PF02480.16 OEU15028.1 - 0.17 10.6 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FlgM PF04316.13 OEU15029.1 - 0.66 10.4 8.5 0.059 13.7 1.0 3.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Serglycin PF04360.12 OEU15030.1 - 5 7.1 12.0 2.1 8.3 6.9 2.8 1 1 1 2 2 2 0 Serglycin TPR_MLP1_2 PF07926.12 OEU15031.1 - 0.012 15.7 2.3 0.012 15.7 2.3 6.3 3 3 4 7 7 7 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OEU15031.1 - 0.013 15.9 2.2 0.013 15.9 2.2 7.4 3 2 2 5 5 5 0 Cell division protein ZapB TolA_bind_tri PF16331.5 OEU15031.1 - 0.029 14.4 23.9 0.038 14.0 2.3 4.5 3 1 1 4 4 4 0 TolA binding protein trimerisation BLOC1_2 PF10046.9 OEU15031.1 - 1.1 9.6 20.1 0.059 13.7 3.3 4.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 OEU15031.1 - 3.1 8.3 15.7 3.8 8.0 0.3 5.4 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Amino_oxidase PF01593.24 OEU15032.1 - 2.4e-12 46.9 1.0 0.00012 21.6 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU15032.1 - 4.2e-07 30.1 0.1 1.1e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU15032.1 - 0.00054 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 OEU15032.1 - 0.13 11.5 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ParE_toxin PF05016.15 OEU15033.1 - 0.088 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Sigma_reg_N PF13800.6 OEU15034.1 - 0.051 13.9 1.5 0.36 11.2 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF929 PF06053.11 OEU15034.1 - 0.25 10.6 1.4 1.3 8.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF929) DUF4330 PF14221.6 OEU15034.1 - 0.3 11.3 1.8 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) CD34_antigen PF06365.12 OEU15034.1 - 6.6 6.3 8.4 14 5.2 0.2 2.5 2 0 0 2 2 2 0 CD34/Podocalyxin family eIF2A PF08662.11 OEU15035.1 - 9.2e-51 172.5 0.0 1.8e-48 165.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PspA_IM30 PF04012.12 OEU15036.1 - 0.0022 17.6 2.4 0.0033 17.0 2.4 1.3 1 0 0 1 1 1 1 PspA/IM30 family SelR PF01641.18 OEU15037.1 - 0.0034 17.4 0.2 0.013 15.6 0.2 1.8 1 1 0 1 1 1 1 SelR domain 2Fe-2S_thioredx PF01257.19 OEU15038.1 - 5e-05 23.2 0.9 0.00018 21.4 0.4 2.0 2 0 0 2 2 2 1 Thioredoxin-like [2Fe-2S] ferredoxin FxsA PF04186.13 OEU15039.1 - 0.026 14.6 4.3 3.1 8.0 0.2 3.5 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein DUF4731 PF15875.5 OEU15039.1 - 0.68 10.2 2.4 3.7 7.8 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) DNA_processg_A PF02481.15 OEU15040.1 - 3.7e-06 26.3 0.0 4.3e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 DNA recombination-mediator protein A Cyto_heme_lyase PF01265.17 OEU15041.1 - 6.2e-47 160.6 6.3 6.2e-47 160.6 6.3 4.5 2 2 1 3 3 3 2 Cytochrome c/c1 heme lyase FeS_assembly_P PF01883.19 OEU15042.1 - 1.8e-11 44.1 0.0 6.8e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Cullin PF00888.22 OEU15043.1 - 1.1e-202 675.0 1.1 1.3e-202 674.7 1.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OEU15043.1 - 1.3e-28 98.8 0.2 3.5e-28 97.4 0.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1803 PF08820.10 OEU15043.1 - 0.044 13.8 0.3 13 5.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1803) Cnd1 PF12717.7 OEU15044.1 - 3.5e-22 79.2 0.6 4.2e-14 52.9 0.0 6.0 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OEU15044.1 - 5.7e-07 29.2 20.2 0.013 15.7 0.6 7.6 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.20 OEU15044.1 - 1.2e-05 24.2 4.5 0.0015 17.2 0.2 3.3 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 OEU15044.1 - 4.1e-05 22.9 0.7 0.00089 18.5 0.0 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OEU15044.1 - 0.00023 21.5 8.5 0.0026 18.1 0.5 5.4 6 1 0 6 6 6 1 HEAT repeats HupH_C PF04809.13 OEU15044.1 - 0.022 14.4 0.1 0.1 12.3 0.1 2.1 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region CLASP_N PF12348.8 OEU15044.1 - 0.57 9.7 4.2 2.4 7.6 0.2 3.1 2 1 1 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 OEU15044.1 - 5.3 7.7 9.3 7.6 7.2 0.7 5.2 4 1 1 5 5 5 0 HEAT-like repeat His_Phos_1 PF00300.22 OEU15045.1 - 7.5e-33 113.9 0.0 1.2e-20 74.0 0.0 4.1 4 0 0 4 4 4 4 Histidine phosphatase superfamily (branch 1) BUD22 PF09073.10 OEU15045.1 - 0.051 12.9 8.5 0.096 12.0 8.5 1.4 1 0 0 1 1 1 0 BUD22 LRR_8 PF13855.6 OEU15046.1 - 1.7e-18 66.1 22.4 0.00011 21.9 0.8 5.2 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OEU15046.1 - 7.7e-17 61.1 23.5 0.00017 21.9 0.6 6.9 3 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU15046.1 - 1.6e-09 37.0 10.5 13 6.8 0.0 9.8 10 1 0 10 10 10 3 Leucine Rich Repeat ODC_AZ PF02100.17 OEU15046.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Ornithine decarboxylase antizyme DUF3802 PF12290.8 OEU15047.1 - 0.026 15.0 0.3 0.067 13.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) FA_desaturase PF00487.24 OEU15047.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase zf-RING_2 PF13639.6 OEU15048.1 - 1.2e-13 51.1 5.3 1.6e-13 50.7 5.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU15048.1 - 3.7e-10 39.4 1.9 3.7e-10 39.4 1.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU15048.1 - 6.5e-10 38.7 4.2 9.6e-10 38.2 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU15048.1 - 2.5e-08 33.6 3.8 3.7e-08 33.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU15048.1 - 4.1e-08 33.0 3.4 5.2e-08 32.6 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU15048.1 - 3.3e-07 30.5 7.0 1.5e-06 28.4 7.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OEU15048.1 - 7e-06 25.8 5.1 9.5e-06 25.4 5.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OEU15048.1 - 7.1e-06 25.9 0.7 7.1e-06 25.9 0.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU15048.1 - 1.4e-05 24.9 5.2 1.9e-05 24.5 5.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OEU15048.1 - 0.0024 17.9 2.6 0.0029 17.6 2.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OEU15048.1 - 0.0024 18.0 6.1 0.19 11.9 6.1 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OEU15048.1 - 0.0058 16.2 3.0 0.012 15.2 3.0 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OEU15048.1 - 0.017 15.2 2.5 0.043 13.9 2.5 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 OEU15048.1 - 0.019 14.8 2.1 0.03 14.1 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OEU15048.1 - 0.067 13.5 2.9 0.099 13.0 2.9 1.3 1 0 0 1 1 1 0 RING-like domain Antistasin PF02822.14 OEU15048.1 - 0.48 11.1 3.8 54 4.6 0.1 3.1 3 0 0 3 3 3 0 Antistasin family zf-C3H2C3 PF17122.5 OEU15048.1 - 5.8 7.1 7.8 0.53 10.4 2.9 1.9 2 1 0 2 2 1 0 Zinc-finger DUF1499 PF07386.11 OEU15049.1 - 4.4e-06 27.2 0.9 1.5e-05 25.5 0.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1499) YGGT PF02325.17 OEU15050.1 - 1e-09 38.6 2.3 1.6e-09 38.0 2.3 1.3 1 0 0 1 1 1 1 YGGT family AMP-binding PF00501.28 OEU15051.1 - 0.0039 15.8 0.0 0.0047 15.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NUC129 PF08157.11 OEU15054.1 - 1.7 9.1 9.1 1.9 8.9 1.6 2.4 2 0 0 2 2 2 0 NUC129 domain DUF4106 PF13388.6 OEU15054.1 - 9.8 5.3 18.0 18 4.4 18.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Rrp40_N PF18311.1 OEU15055.1 - 0.002 18.0 4.7 2.1 8.3 0.1 4.7 3 1 1 4 4 4 2 Exosome complex exonuclease Rrp40 N-terminal domain PSCyt3 PF07627.11 OEU15055.1 - 0.11 12.7 9.5 3.9 7.8 0.4 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1588) Pkinase_Tyr PF07714.17 OEU15056.1 - 4.4e-57 193.3 0.0 5.3e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU15056.1 - 3.3e-51 174.2 0.0 4.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OEU15056.1 - 0.0018 17.3 0.0 0.0094 14.9 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OEU15056.1 - 0.029 13.7 0.0 0.063 12.6 0.0 1.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OEU15056.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU15056.1 - 0.24 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CAP_GLY PF01302.25 OEU15057.1 - 8.3e-20 70.6 1.9 1.2e-19 70.0 0.9 1.8 2 0 0 2 2 2 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OEU15057.1 - 1.2e-13 51.3 1.0 2.6e-13 50.2 1.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 OEU15057.1 - 1.4e-05 24.8 0.1 2.9e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C97 PF05903.14 OEU15058.1 - 3.5e-21 75.6 0.1 7.4e-20 71.3 0.1 2.4 1 1 0 1 1 1 1 PPPDE putative peptidase domain LRR_4 PF12799.7 OEU15060.1 - 2.9e-06 27.5 1.9 1.5 9.4 0.2 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU15060.1 - 2.4e-05 24.0 0.4 0.025 14.3 0.1 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_2 PF07723.13 OEU15060.1 - 0.012 16.2 0.2 2.4 9.0 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_1 PF00560.33 OEU15060.1 - 0.33 11.7 4.6 54 4.9 0.1 4.7 4 2 1 5 5 5 0 Leucine Rich Repeat OCD_Mu_crystall PF02423.15 OEU15061.1 - 9.6e-55 185.7 0.2 1.2e-54 185.4 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_2 PF03446.15 OEU15061.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OEU15061.1 - 0.09 13.4 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sec10 PF07393.11 OEU15062.1 - 1.3e-19 70.1 0.2 4.4e-08 32.0 0.1 3.7 2 1 0 2 2 2 2 Exocyst complex component Sec10 Linker_histone PF00538.19 OEU15063.1 - 2.9e-13 50.0 1.3 2.9e-13 50.0 1.3 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family DUF3006 PF11213.8 OEU15063.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) RR_TM4-6 PF06459.12 OEU15063.1 - 0.91 9.3 22.7 1.2 8.9 22.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mitofilin PF09731.9 OEU15063.1 - 4.2 6.1 29.6 4.6 5.9 29.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PEN-2 PF10251.9 OEU15064.1 - 4.3e-07 30.3 0.0 2.2e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase Lipase_3 PF01764.25 OEU15065.1 - 1.6e-13 50.7 0.0 5.4e-11 42.5 0.0 2.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OEU15065.1 - 0.0009 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 OEU15065.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_L27e PF01777.18 OEU15067.1 - 0.053 13.9 0.2 0.19 12.1 0.2 1.9 1 0 0 1 1 1 0 Ribosomal L27e protein family SelK_SelG PF10961.8 OEU15067.1 - 0.057 14.0 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Cnd3 PF12719.7 OEU15068.1 - 7.8e-24 84.4 2.6 7.8e-24 84.4 2.6 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OEU15068.1 - 1.9e-07 31.4 0.3 2.5 8.6 0.2 4.3 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 OEU15068.1 - 0.0029 17.7 0.4 1.1e+02 3.5 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat CDC45 PF02724.14 OEU15068.1 - 0.069 11.4 3.4 0.12 10.6 3.4 1.3 1 0 0 1 1 1 0 CDC45-like protein HEAT_EZ PF13513.6 OEU15068.1 - 0.081 13.5 0.2 8.6 7.0 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat DUF4042 PF13251.6 OEU15068.1 - 0.095 12.4 2.5 51 3.5 0.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) Thioredoxin PF00085.20 OEU15069.1 - 1.3e-06 28.3 0.0 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 OEU15069.1 - 0.002 18.0 0.0 0.5 10.2 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OEU15069.1 - 0.057 13.6 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU15069.1 - 0.11 13.0 0.0 7.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain Zn-ribbon_8 PF09723.10 OEU15070.1 - 0.0003 20.8 1.4 0.00049 20.2 1.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-Dof PF02701.15 OEU15070.1 - 0.00057 20.0 1.3 0.025 14.7 0.0 2.1 2 0 0 2 2 2 1 Dof domain, zinc finger TF_Zn_Ribbon PF08271.12 OEU15070.1 - 0.00072 19.0 3.4 0.019 14.5 0.1 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 OEU15070.1 - 0.001 18.7 1.1 0.013 15.2 0.2 2.3 2 0 0 2 2 2 1 A2L zinc ribbon domain zf-Mss51 PF13824.6 OEU15070.1 - 0.0018 18.3 5.6 0.027 14.6 0.3 2.2 1 1 1 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_3 PF13878.6 OEU15070.1 - 0.026 14.3 0.7 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO HypA PF01155.19 OEU15070.1 - 0.029 14.4 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 OEU15070.1 - 0.066 12.6 6.6 1.5 8.3 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OEU15070.1 - 0.17 11.8 1.0 0.63 10.0 1.1 1.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 OEU15070.1 - 0.21 11.3 0.8 0.21 11.3 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Rubredoxin PF00301.20 OEU15070.1 - 0.22 11.6 11.2 1.6 8.8 2.5 2.2 1 1 1 2 2 2 0 Rubredoxin TFIIS_C PF01096.18 OEU15070.1 - 0.26 11.2 2.0 4 7.4 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.6 OEU15070.1 - 0.88 10.1 7.2 4.6 7.8 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Ubiq_cyt_C_chap PF03981.12 OEU15071.1 - 6.2e-13 49.0 0.2 1.2e-12 48.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 OEU15071.1 - 1.5e-08 34.5 1.1 4e-08 33.2 1.1 1.8 1 0 0 1 1 1 1 WW domain Transket_pyr PF02779.24 OEU15072.1 - 3.7e-40 137.5 0.0 4.9e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OEU15072.1 - 1.8e-30 105.4 0.0 2.7e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pentaxin PF00354.17 OEU15072.1 - 0.055 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family cNMP_binding PF00027.29 OEU15073.1 - 7.1e-27 93.3 1.3 5.1e-19 68.1 0.1 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 OEU15074.1 - 9.4e-59 198.9 0.0 1.1e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15074.1 - 1.7e-28 99.7 0.0 2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OEU15074.1 - 0.025 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OEU15074.1 - 0.14 12.1 0.0 1 9.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S15 PF00312.22 OEU15075.1 - 3.9e-30 103.9 0.5 6e-30 103.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 MT PF12777.7 OEU15075.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Proteasome PF00227.26 OEU15076.1 - 9.6e-57 191.5 0.3 1.2e-56 191.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU15076.1 - 7.7e-13 47.9 0.0 1.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature polyprenyl_synt PF00348.17 OEU15077.1 - 4.5e-60 202.9 0.0 5.4e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase UbiA PF01040.18 OEU15077.1 - 0.23 10.7 0.0 0.5 9.6 0.0 1.5 2 0 0 2 2 2 0 UbiA prenyltransferase family Proteasome PF00227.26 OEU15079.1 - 1.5e-33 115.9 0.0 1.9e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Chorismate_bind PF00425.18 OEU15080.1 - 2e-35 122.6 0.0 2.3e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 chorismate binding enzyme Ints3 PF10189.9 OEU15080.1 - 0.072 12.4 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 3 TPP_enzyme_N PF02776.18 OEU15081.1 - 1.6e-21 76.7 0.0 1.7e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Polyketide_cyc2 PF10604.9 OEU15082.1 - 2.7e-09 37.5 0.3 2.9e-09 37.4 0.3 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OEU15082.1 - 5.1e-06 26.7 0.3 6.1e-06 26.5 0.3 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport USP8_dimer PF08969.11 OEU15083.1 - 0.002 18.3 1.4 0.0035 17.5 0.1 2.1 2 0 0 2 2 2 1 USP8 dimerisation domain DUF1599 PF07659.11 OEU15083.1 - 0.55 10.7 2.1 0.76 10.3 0.2 2.2 2 1 1 3 3 3 0 Nucleotide modification associated domain 1 PDZ PF00595.24 OEU15084.1 - 2.1e-07 31.2 0.1 4.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU15084.1 - 0.001 19.3 0.2 0.0023 18.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU15084.1 - 0.0056 16.5 1.6 0.02 14.7 1.6 2.0 1 1 0 1 1 1 1 PDZ domain EFTUD2 PF16004.5 OEU15085.1 - 0.82 10.3 7.1 0.53 10.9 2.8 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MRP-S26 PF14943.6 OEU15085.1 - 6.5 6.6 23.9 0.48 10.3 18.6 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF179 PF02622.15 OEU15086.1 - 1.4e-29 103.1 0.0 2.3e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 PAP1 PF08601.10 OEU15086.1 - 0.13 12.0 8.6 0.19 11.5 8.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4698 PF15769.5 OEU15086.1 - 0.53 9.3 4.6 0.73 8.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) SR-25 PF10500.9 OEU15086.1 - 2.2 7.8 12.6 3.8 7.0 12.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S24 PF00717.23 OEU15087.1 - 1.4e-14 53.7 0.0 8.8e-13 48.0 0.0 2.4 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OEU15087.1 - 0.00084 19.1 0.2 0.0075 16.1 0.2 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 DUF5641 PF18701.1 OEU15087.1 - 0.0042 17.2 1.1 0.85 9.8 0.0 3.0 2 1 1 3 3 3 2 Family of unknown function (DUF5641) Glyco_transf_92 PF01697.27 OEU15088.1 - 1.4e-14 54.4 9.5 2.5e-13 50.3 9.5 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU15088.1 - 3.1e-09 37.2 0.3 9.9e-09 35.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ank_2 PF12796.7 OEU15089.1 - 3e-18 66.2 0.4 2.3e-09 37.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU15089.1 - 2e-16 59.6 0.4 8.7e-08 32.3 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OEU15089.1 - 4e-16 59.1 1.2 1.3e-08 35.2 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU15089.1 - 8.9e-13 48.2 0.5 0.0022 18.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU15089.1 - 4.7e-12 45.0 0.2 0.00034 20.8 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat DRY_EERY PF09750.9 OEU15090.1 - 0.021 15.1 2.7 0.032 14.5 2.7 1.3 1 0 0 1 1 1 0 Alternative splicing regulator Gar1 PF04410.14 OEU15090.1 - 0.027 14.2 3.2 0.047 13.5 3.2 1.4 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Menin PF05053.13 OEU15090.1 - 0.55 8.5 6.9 0.72 8.1 6.9 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 OEU15091.1 - 6.8e-33 114.1 0.0 3.6e-32 111.8 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15091.1 - 5.3e-32 111.1 0.0 7.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU15091.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Daxx PF03344.15 OEU15091.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain Kinase-like PF14531.6 OEU15091.1 - 0.19 11.0 0.0 0.55 9.5 0.0 1.7 1 1 0 1 1 1 0 Kinase-like PBP1_TM PF14812.6 OEU15092.1 - 1.4 9.3 4.5 0.32 11.4 1.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TraT PF05818.12 OEU15093.1 - 0.14 11.9 0.7 0.23 11.1 0.7 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein PBP1_TM PF14812.6 OEU15094.1 - 0.22 11.9 4.2 0.73 10.2 2.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.8 OEU15094.1 - 1.1 9.8 5.9 1.5 9.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PGA2 PF07543.12 OEU15094.1 - 1.5 8.8 4.4 5 7.1 0.8 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 INCENP_ARK-bind PF03941.15 OEU15094.1 - 7.7 6.5 9.3 0.33 10.9 2.0 2.3 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Glyco_transf_92 PF01697.27 OEU15097.1 - 4.1e-23 82.4 1.1 6.6e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU15097.1 - 4.5e-06 27.1 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 OEU15098.1 - 1.8e-19 70.4 0.1 3.7e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU15098.1 - 0.00055 20.4 0.0 0.0015 19.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ustilago_mating PF05722.12 OEU15098.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Arm PF00514.23 OEU15099.1 - 2.1e-33 113.3 15.9 2.1e-06 27.6 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OEU15099.1 - 1.7e-14 53.9 0.1 0.00058 20.3 0.0 6.0 6 0 0 6 6 6 3 HEAT-like repeat Arm_3 PF16186.5 OEU15099.1 - 2.1e-12 46.4 1.0 6.6e-12 44.8 1.0 1.9 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 OEU15099.1 - 1.1e-10 40.8 1.5 0.03 14.6 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OEU15099.1 - 2e-09 37.7 0.1 0.00099 19.5 0.0 3.9 3 2 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 OEU15099.1 - 0.2 12.4 2.9 94 4.1 0.0 4.7 5 1 0 5 5 5 0 PBS lyase HEAT-like repeat SNARE PF05739.19 OEU15100.1 - 0.00018 21.4 0.7 0.00062 19.7 0.0 2.4 2 0 0 2 2 2 1 SNARE domain Utp12 PF04003.12 OEU15100.1 - 0.06 13.7 0.2 0.06 13.7 0.2 2.2 3 0 0 3 3 3 0 Dip2/Utp12 Family ODV-E18 PF10717.9 OEU15100.1 - 0.52 10.2 2.6 1.6 8.7 2.6 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 MscS_TM PF12794.7 OEU15100.1 - 9.5 5.0 6.6 3.8 6.3 0.0 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 PGK PF00162.19 OEU15101.1 - 2.5e-151 503.9 0.8 2.8e-151 503.8 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TFIIS_C PF01096.18 OEU15102.1 - 9.4e-21 73.4 2.2 9.4e-21 73.4 2.2 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 OEU15102.1 - 0.0001 21.9 0.8 0.00024 20.7 0.6 1.7 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 OEU15102.1 - 0.00046 20.1 3.1 0.00087 19.2 0.4 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 OEU15102.1 - 0.0031 17.4 0.1 0.17 11.9 0.0 2.6 2 1 0 2 2 2 1 PhnA Zinc-Ribbon Cript PF10235.9 OEU15102.1 - 0.042 14.4 3.2 0.054 14.1 0.0 2.3 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT Terminase_GpA PF05876.12 OEU15102.1 - 0.061 11.9 1.3 0.057 12.0 1.3 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.6 OEU15102.1 - 0.066 13.6 3.4 0.22 11.9 0.7 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar HNH_5 PF14279.6 OEU15102.1 - 0.11 12.4 2.0 0.11 12.4 0.0 2.1 2 1 1 3 3 3 0 HNH endonuclease zf-RRN7 PF11781.8 OEU15102.1 - 0.28 10.9 6.0 5.2 6.8 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RNA_POL_M_15KD PF02150.16 OEU15102.1 - 0.41 10.6 8.8 0.15 12.0 0.9 3.3 3 1 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 OEU15102.1 - 1.1 9.0 6.8 12 5.7 0.0 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Arm PF00514.23 OEU15103.1 - 7.3e-48 159.2 13.1 4.8e-11 42.3 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 OEU15103.1 - 5.9e-12 45.0 3.4 1.8e-11 43.4 2.2 2.5 2 1 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 OEU15103.1 - 1.1e-11 44.9 0.4 1.4e-05 25.5 0.0 5.3 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 OEU15103.1 - 6e-11 41.6 4.5 0.0027 17.8 0.0 6.0 7 0 0 7 7 6 2 HEAT repeat IBB PF01749.20 OEU15103.1 - 2.1e-10 40.9 2.4 2.1e-10 40.9 2.4 2.3 3 0 0 3 3 3 1 Importin beta binding domain HEAT_2 PF13646.6 OEU15103.1 - 5.2e-10 39.6 0.1 0.0022 18.3 0.0 4.2 2 1 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 OEU15103.1 - 8.8e-09 35.6 0.1 0.0058 16.7 0.0 3.2 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 OEU15103.1 - 9.6e-05 22.5 2.0 2 8.7 0.1 4.5 3 2 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 OEU15103.1 - 0.00024 21.1 2.5 0.026 14.5 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) NopRA1 PF16201.5 OEU15103.1 - 0.00092 18.8 0.2 0.38 10.3 0.0 3.4 2 2 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Adaptin_N PF01602.20 OEU15103.1 - 0.0013 17.4 1.2 0.024 13.2 0.1 2.8 1 1 1 2 2 2 1 Adaptin N terminal region Mo25 PF08569.11 OEU15103.1 - 0.01 15.2 0.3 0.042 13.2 0.1 1.9 1 1 1 2 2 2 0 Mo25-like HEAT_PBS PF03130.16 OEU15103.1 - 0.017 15.7 0.1 31 5.6 0.0 4.1 4 1 0 4 4 3 0 PBS lyase HEAT-like repeat DUF3385 PF11865.8 OEU15103.1 - 0.06 13.3 0.1 7.5 6.4 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) Arm_2 PF04826.13 OEU15103.1 - 0.07 12.6 1.4 1.5 8.2 0.1 3.2 2 2 1 3 3 3 0 Armadillo-like tRNA-synt_1 PF00133.22 OEU15104.1 - 1.9e-72 244.4 0.1 6e-48 163.5 0.0 3.5 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OEU15104.1 - 9.5e-67 224.1 0.0 1.7e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 OEU15104.1 - 2e-25 89.4 0.2 2.6e-17 62.7 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OEU15104.1 - 1.2e-13 51.3 0.0 4.2e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OEU15104.1 - 0.00073 19.0 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 OEU15104.1 - 0.0093 14.9 0.0 0.76 8.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.25 OEU15104.1 - 0.031 13.6 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Beta_helix PF13229.6 OEU15106.1 - 6.1e-05 22.9 2.7 0.00016 21.6 2.7 1.7 1 0 0 1 1 1 1 Right handed beta helix region CBM_4_9 PF02018.17 OEU15106.1 - 0.046 14.0 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 Carbohydrate binding domain Abhydrolase_1 PF00561.20 OEU15107.1 - 2.7e-13 50.1 0.1 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU15107.1 - 7.9e-11 41.7 0.0 1.5e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU15107.1 - 9e-10 39.5 0.0 1.2e-09 39.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OEU15107.1 - 0.00061 19.4 0.0 0.0021 17.6 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 OEU15107.1 - 0.0012 18.3 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1057 PF06342.12 OEU15107.1 - 0.0017 17.5 0.0 0.0055 15.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 OEU15107.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Say1_Mug180 PF10340.9 OEU15107.1 - 0.015 14.1 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase IMS_HHH PF11798.8 OEU15107.1 - 0.017 15.4 0.0 0.76 10.2 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif PTE PF02126.18 OEU15107.1 - 0.018 14.5 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotriesterase family Ser_hydrolase PF06821.13 OEU15107.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase PAF-AH_p_II PF03403.13 OEU15107.1 - 0.06 11.9 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 OEU15107.1 - 0.097 12.4 0.1 0.66 9.6 0.0 2.3 3 0 0 3 3 3 0 PGAP1-like protein Sarcolipin PF05366.11 OEU15108.1 - 0.8 9.5 3.5 2 8.2 3.5 1.7 1 1 0 1 1 1 0 Sarcolipin DHHC PF01529.20 OEU15108.1 - 3.1 7.9 4.9 5.4 7.1 4.9 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_holin_3_6 PF07332.11 OEU15108.1 - 3.6 7.6 8.1 2.4 8.2 5.7 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Cullin_binding PF03556.15 OEU15109.1 - 3.4e-15 56.5 0.1 3.8e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Cullin binding Thioredoxin PF00085.20 OEU15110.1 - 1.8e-21 76.1 0.4 2.4e-21 75.6 0.4 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OEU15110.1 - 1.9e-05 24.6 0.1 3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OEU15110.1 - 2.3e-05 24.6 0.2 0.0056 17.0 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU15110.1 - 0.00085 19.7 1.8 0.058 13.9 1.8 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU15110.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 OEU15110.1 - 0.032 13.6 0.2 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family T4_deiodinase PF00837.17 OEU15110.1 - 0.037 13.3 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase DUF1635 PF07795.11 OEU15110.1 - 0.17 11.7 5.0 0.24 11.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Peptidase_C14 PF00656.22 OEU15111.1 - 1.2e-45 156.4 0.5 3.3e-33 115.7 0.3 2.0 2 0 0 2 2 2 2 Caspase domain Peptidase_C13 PF01650.18 OEU15111.1 - 0.16 11.4 0.3 0.38 10.2 0.2 1.6 1 1 0 1 1 1 0 Peptidase C13 family Pkinase PF00069.25 OEU15112.1 - 1.4e-73 247.6 0.0 1.6e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15112.1 - 5e-35 121.0 0.0 6.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU15112.1 - 5.2e-07 29.3 0.0 1.1e-06 28.1 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OEU15112.1 - 0.00098 18.0 0.0 0.0015 17.4 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OEU15112.1 - 0.0015 17.6 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OEU15112.1 - 0.0015 18.2 0.8 0.0029 17.2 0.8 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OEU15112.1 - 0.0033 16.8 0.2 0.0054 16.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU15112.1 - 0.0041 17.1 0.1 0.016 15.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OEU15112.1 - 0.018 14.1 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 OEU15112.1 - 0.048 13.2 0.0 0.076 12.5 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL CBFB_NFYA PF02045.15 OEU15114.1 - 0.25 12.0 3.2 0.51 11.0 3.2 1.5 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Metallophos PF00149.28 OEU15115.1 - 6.4e-14 52.9 1.0 8.8e-14 52.5 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OEU15115.1 - 1.4e-05 25.3 0.0 3.9e-05 23.9 0.0 1.7 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain MAGE PF01454.19 OEU15116.1 - 4.3e-22 78.9 0.0 6.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 MAGE family Utp11 PF03998.13 OEU15117.1 - 7.9e-64 215.9 34.2 4e-63 213.6 34.2 1.8 1 1 0 1 1 1 1 Utp11 protein DUF4144 PF13642.6 OEU15117.1 - 0.31 11.6 1.9 1 10.0 0.0 2.5 3 0 0 3 3 3 0 protein structure with unknown function Methyltransf_18 PF12847.7 OEU15118.1 - 2.3e-26 92.6 4.7 2.6e-23 82.6 0.9 2.9 3 0 0 3 3 3 2 Methyltransferase domain TrmK PF04816.12 OEU15118.1 - 4e-22 78.8 5.3 6.7e-17 61.7 0.9 2.1 2 0 0 2 2 2 2 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_25 PF13649.6 OEU15118.1 - 3.5e-07 30.9 0.3 8.9e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OEU15118.1 - 1.8e-05 24.3 0.3 3e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OEU15118.1 - 2.2e-05 24.3 0.5 2.2e-05 24.3 0.5 1.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OEU15118.1 - 2.4e-05 23.9 0.8 4.6e-05 23.0 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OEU15118.1 - 0.00048 20.7 0.1 0.0051 17.4 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU15118.1 - 0.0091 16.7 0.6 0.5 11.1 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Helicase_C PF00271.31 OEU15119.1 - 2.4e-21 76.1 0.0 3.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LLGL PF08366.13 OEU15119.1 - 0.095 13.1 0.0 0.23 11.8 0.0 1.8 1 1 0 1 1 1 0 LLGL2 ELYS-bb PF16687.5 OEU15119.1 - 0.17 10.4 0.0 3.3 6.2 0.0 2.0 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin DEAD PF00270.29 OEU15120.1 - 1.1e-28 100.2 0.1 1.2e-28 100.0 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 OEU15120.1 - 3.2e-07 30.0 0.1 4.7e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 OEU15120.1 - 2.1e-06 27.8 0.0 2.5e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TF_Zn_Ribbon PF08271.12 OEU15121.1 - 9.2e-08 31.5 1.3 2.1e-07 30.4 1.3 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding EF-hand_1 PF00036.32 OEU15122.1 - 0.00022 20.6 0.1 0.0025 17.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OEU15122.1 - 0.0005 20.5 2.0 0.0018 18.7 0.1 3.0 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU15122.1 - 0.0014 18.4 0.5 0.0092 15.8 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 OEU15122.1 - 0.01 15.8 0.2 0.04 13.9 0.1 2.0 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OEU15122.1 - 0.023 15.0 0.5 0.11 12.8 0.0 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 OEU15122.1 - 0.045 13.3 4.5 0.052 13.1 0.6 2.6 2 0 0 2 2 2 0 EF hand VHS PF00790.19 OEU15122.1 - 1.7 8.5 5.2 25 4.7 0.1 3.0 3 0 0 3 3 3 0 VHS domain MCM PF00493.23 OEU15123.1 - 8.5e-67 224.5 0.0 1.2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 OEU15123.1 - 7.5e-21 74.4 2.0 1.7e-20 73.2 2.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OEU15123.1 - 2e-13 50.3 1.2 8.8e-13 48.2 0.1 2.2 2 0 0 2 2 2 1 MCM OB domain Mg_chelatase PF01078.21 OEU15123.1 - 6.3e-07 29.0 0.3 1.9e-06 27.4 0.1 1.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU15123.1 - 0.00045 20.2 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) KH_8 PF17903.1 OEU15124.1 - 5.1e-30 103.4 0.0 1.2e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OEU15124.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 KH domain Pup PF05639.11 OEU15124.1 - 0.82 10.6 5.0 3.4 8.6 5.0 2.1 1 0 0 1 1 1 0 Pup-like protein ESP PF16590.5 OEU15124.1 - 0.94 9.8 4.2 2.1 8.7 4.2 1.6 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Snf7 PF03357.21 OEU15125.1 - 4.8e-13 49.1 8.5 5.8e-13 48.8 8.5 1.1 1 0 0 1 1 1 1 Snf7 GrpE PF01025.19 OEU15125.1 - 0.0012 18.5 2.0 0.0012 18.5 2.0 1.6 2 0 0 2 2 2 1 GrpE DUF842 PF05811.13 OEU15125.1 - 0.0048 16.6 2.2 0.0071 16.0 2.0 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) ATS PF15445.6 OEU15125.1 - 0.035 13.5 0.5 0.043 13.2 0.5 1.2 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 DUF1844 PF08899.11 OEU15125.1 - 0.079 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Mt_ATP-synt_D PF05873.12 OEU15125.1 - 0.097 12.5 1.2 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DMSP_lyase PF16867.5 OEU15125.1 - 0.12 12.0 0.0 0.77 9.4 0.0 2.2 2 1 1 3 3 3 0 Dimethlysulfonioproprionate lyase PX PF00787.24 OEU15127.1 - 2.8e-17 62.7 0.0 5.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SUIM_assoc PF16619.5 OEU15127.1 - 5.3 7.2 27.4 7.4 6.7 4.4 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 AMP-binding PF00501.28 OEU15128.1 - 1.1e-84 284.5 0.0 1.5e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OEU15128.1 - 2.8e-24 84.8 0.5 6e-24 83.7 0.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OEU15128.1 - 7e-24 84.6 0.0 1.5e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 OEU15129.1 - 2.8e-48 164.7 1.6 3.7e-48 164.2 1.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU15129.1 - 1e-27 96.5 0.7 2.4e-27 95.3 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU15129.1 - 3.9e-14 53.0 0.0 1.5e-13 51.1 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU15129.1 - 0.00029 20.1 4.8 0.0022 17.2 3.8 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 OEU15129.1 - 0.0029 17.5 0.1 0.52 10.2 0.0 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OEU15129.1 - 0.005 16.4 0.1 0.057 13.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 OEU15129.1 - 0.012 14.7 5.1 0.094 11.8 2.7 2.4 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 OEU15129.1 - 2.5 7.4 7.0 2.6 7.3 3.6 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase AAA_11 PF13086.6 OEU15130.1 - 6.6e-27 94.9 0.3 2.3e-23 83.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 OEU15130.1 - 1.9e-10 40.7 0.8 2.8e-10 40.2 0.4 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OEU15130.1 - 0.0019 18.5 0.0 0.0032 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU15130.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OEU15130.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NUC173 PF08161.12 OEU15130.1 - 0.049 13.3 0.0 1.6 8.3 0.0 2.1 1 1 1 2 2 2 0 NUC173 domain AAA_12 PF13087.6 OEU15131.1 - 6.4e-20 71.6 0.3 6.8e-20 71.5 0.3 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OEU15131.1 - 9.8e-05 22.1 0.1 0.00025 20.8 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 OEU15131.1 - 0.077 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF1481 PF07356.12 OEU15132.1 - 0.00015 21.6 0.0 1.9 8.2 0.0 3.4 1 1 3 4 4 4 4 Protein of unknown function (DUF1481) DAPG_hydrolase PF18089.1 OEU15132.1 - 0.00067 19.3 0.0 23 4.5 0.0 3.8 1 1 3 4 4 4 0 DAPG hydrolase PhiG domain AGOG PF09171.10 OEU15132.1 - 0.0031 16.9 9.8 1.8 7.8 0.6 3.7 1 1 3 4 4 4 3 N-glycosylase/DNA lyase Flp_N PF03930.14 OEU15132.1 - 0.0065 16.4 3.2 67 3.6 0.0 4.4 4 0 0 4 4 4 0 Recombinase Flp protein N-terminus AAA_lid_3 PF17862.1 OEU15132.1 - 0.012 15.4 0.0 1.5e+02 2.3 0.0 4.2 4 0 0 4 4 4 0 AAA+ lid domain DHNA PF04038.12 OEU15132.1 - 0.051 14.1 8.2 4 8.0 0.4 3.6 1 1 4 5 5 5 0 Dihydroneopterin aldolase DUF2986 PF11661.8 OEU15132.1 - 0.056 14.0 11.8 4.2 8.0 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2986) YqzH PF14164.6 OEU15132.1 - 0.11 12.6 1.1 7.9 6.6 0.0 3.8 5 0 0 5 5 5 0 YqzH-like protein Rep_3 PF01051.21 OEU15132.1 - 0.47 10.2 8.4 80 2.9 0.0 4.5 1 1 2 3 3 3 0 Initiator Replication protein Aerolysin PF01117.20 OEU15132.1 - 0.76 8.9 5.8 3 7.0 0.3 3.6 2 1 3 5 5 5 0 Aerolysin toxin Aspzincin_M35 PF14521.6 OEU15132.1 - 1 9.9 6.2 2.2e+02 2.3 0.1 4.5 5 1 0 5 5 5 0 Lysine-specific metallo-endopeptidase Actin PF00022.19 OEU15133.1 - 5.3e-74 249.3 0.0 8.3e-73 245.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OEU15133.1 - 4.6e-08 32.2 0.0 0.0044 15.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Peptidase_S41 PF03572.18 OEU15134.1 - 5.9e-18 65.0 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 EPSP_synthase PF00275.20 OEU15135.1 - 6.9e-133 443.4 0.0 7.8e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Tcf25 PF04910.14 OEU15136.1 - 8.2e-50 169.8 4.0 1.2e-49 169.3 4.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DNA_pol3_delta2 PF13177.6 OEU15137.1 - 8.6e-11 41.9 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OEU15137.1 - 8.2e-08 32.6 0.1 2.6e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 OEU15137.1 - 0.0008 19.8 0.0 0.0024 18.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OEU15137.1 - 0.012 15.4 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU15137.1 - 0.014 15.8 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 OEU15137.1 - 0.024 14.8 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 OEU15137.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 OEU15137.1 - 0.057 13.4 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OEU15137.1 - 0.086 13.3 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 OEU15137.1 - 0.098 12.4 0.0 0.57 9.9 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 OEU15137.1 - 0.12 12.2 0.0 14 5.4 0.0 2.7 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain RVT_1 PF00078.27 OEU15138.1 - 1.7e-07 31.0 0.0 4.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU15138.1 - 5.1e-06 27.1 1.2 2.9e-05 24.7 1.2 2.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FUR PF01475.19 OEU15138.1 - 0.069 13.3 0.5 7.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Ferric uptake regulator family DUF3464 PF11947.8 OEU15139.1 - 1.2 8.9 3.6 23 4.7 0.6 2.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 AreA_N PF07573.11 OEU15139.1 - 2.1 9.0 5.5 0.85 10.3 0.2 3.1 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus Tim17 PF02466.19 OEU15142.1 - 0.0013 19.1 3.0 0.0019 18.5 3.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 OEU15142.1 - 0.21 12.0 15.6 0.18 12.2 7.0 2.7 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Cwf_Cwc_15 PF04889.12 OEU15143.1 - 0.00088 19.1 14.5 0.00097 18.9 14.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 OEU15143.1 - 0.0068 15.9 1.3 0.0082 15.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) TFIIF_alpha PF05793.12 OEU15143.1 - 0.039 12.5 20.8 0.044 12.4 20.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 OEU15143.1 - 0.061 12.7 17.4 0.065 12.6 17.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1754 PF08555.10 OEU15143.1 - 0.066 14.0 30.6 2.1 9.2 30.6 2.9 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Rrn6 PF10214.9 OEU15143.1 - 0.13 10.7 8.3 0.15 10.6 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PCM1_C PF15717.5 OEU15143.1 - 0.42 9.3 14.0 0.5 9.0 14.0 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus DUF724 PF05266.14 OEU15143.1 - 0.86 9.4 11.0 1 9.2 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RR_TM4-6 PF06459.12 OEU15143.1 - 1.6 8.5 10.8 1.9 8.3 10.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-I PF07778.11 OEU15143.1 - 1.7 7.3 6.4 1.9 7.1 6.4 1.0 1 0 0 1 1 1 0 Mis6 DUF3827 PF12877.7 OEU15143.1 - 1.7 6.9 10.8 2 6.7 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PDDEXK_6 PF04720.12 OEU15143.1 - 1.9 8.4 8.9 2.2 8.1 8.9 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function NPR3 PF03666.13 OEU15143.1 - 2.3 6.9 13.5 2.6 6.7 13.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 OEU15143.1 - 2.5 6.8 4.9 2.8 6.7 4.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 OEU15143.1 - 3.1 6.7 6.7 3.4 6.6 6.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Rpn3_C PF08375.11 OEU15143.1 - 5.4 7.5 14.4 9 6.8 2.7 2.1 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal CDC45 PF02724.14 OEU15143.1 - 8.9 4.5 16.0 10 4.3 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 OEU15143.1 - 9.4 6.7 21.5 41 4.6 21.5 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phage_pRha PF09669.10 OEU15145.1 - 0.12 13.0 2.0 0.25 11.9 0.3 1.9 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) PWI PF01480.17 OEU15146.1 - 7.8e-21 74.2 0.0 1.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 PWI domain APG12 PF04110.13 OEU15147.1 - 4.8e-29 100.6 0.0 5.4e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OEU15147.1 - 0.00032 20.9 0.0 0.00035 20.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like RNA_pol_Rpb1_1 PF04997.12 OEU15148.1 - 3.7e-88 295.9 0.0 6.2e-88 295.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OEU15148.1 - 4.7e-87 291.8 0.2 6.8e-87 291.3 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OEU15148.1 - 3.5e-73 245.3 0.1 5.8e-73 244.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OEU15148.1 - 7e-34 117.0 0.0 8.8e-33 113.5 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OEU15148.1 - 3.5e-26 91.3 0.0 8.7e-26 90.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2207 PF09972.9 OEU15149.1 - 0.0042 15.9 1.4 0.67 8.7 0.1 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) XPC-binding PF09280.11 OEU15151.1 - 1.9e-21 75.5 11.8 1.9e-21 75.5 11.8 3.3 2 1 1 3 3 3 1 XPC-binding domain UBA PF00627.31 OEU15151.1 - 4.6e-20 71.1 0.4 2.1e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 OEU15151.1 - 1.5e-17 63.0 0.2 2.7e-17 62.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU15151.1 - 0.00013 21.8 0.1 0.00023 20.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OEU15151.1 - 0.0025 18.3 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU15151.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 OEU15151.1 - 0.014 15.1 0.0 0.059 13.1 0.0 2.1 2 0 0 2 2 2 0 CUE domain CCDC85 PF10226.9 OEU15151.1 - 0.086 12.5 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 CCDC85 family MSA-2c PF12238.8 OEU15151.1 - 0.097 12.7 2.6 0.23 11.4 2.6 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c LRR_9 PF14580.6 OEU15152.1 - 1.1e-12 47.8 0.3 4.1e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OEU15152.1 - 1.8e-10 40.9 11.4 0.0019 18.5 0.2 5.8 3 1 0 5 5 5 3 Leucine Rich repeats (2 copies) CAP_GLY PF01302.25 OEU15152.1 - 2e-09 37.4 0.1 4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OEU15152.1 - 1.4e-05 25.4 0.0 4.7e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.6 OEU15152.1 - 0.021 14.6 11.5 6.9 6.5 0.3 5.5 4 2 2 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 OEU15152.1 - 0.74 10.6 10.5 66 4.7 0.0 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat H2O2_YaaD PF03883.14 OEU15153.1 - 1.2e-54 185.3 0.0 1.4e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA DUF630 PF04783.12 OEU15154.1 - 0.41 10.9 2.0 0.78 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF630) RCC1 PF00415.18 OEU15155.1 - 1.4e-43 147.2 14.9 6.4e-09 36.3 0.1 8.2 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU15155.1 - 1.9e-32 110.4 9.3 5.5e-06 26.0 0.0 7.0 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat ChaC PF04752.12 OEU15155.1 - 3.3e-31 108.7 0.0 5.3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 OEU15155.1 - 0.093 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like DUF1289 PF06945.13 OEU15156.1 - 0.071 12.9 1.8 0.1 12.4 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1289) PP2C_2 PF13672.6 OEU15156.1 - 0.098 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C tRNA-synt_1e PF01406.19 OEU15157.1 - 3.6e-118 394.3 0.4 7.2e-118 393.3 0.4 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OEU15157.1 - 5.7e-05 22.0 2.2 0.00052 18.9 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 OEU15157.1 - 0.0026 16.7 0.0 0.0087 15.0 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.22 OEU15157.1 - 0.0078 14.5 0.1 0.034 12.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) YlbD_coat PF14071.6 OEU15157.1 - 0.53 10.6 5.8 0.11 12.8 1.1 2.4 2 0 0 2 2 2 0 Putative coat protein OmpH PF03938.14 OEU15157.1 - 2.2 8.6 23.0 0.037 14.4 3.6 3.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Gluconate_2-dh3 PF13618.6 OEU15157.1 - 2.8 8.2 7.9 7.4 6.8 0.7 3.0 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Phage_T7_Capsid PF05396.11 OEU15157.1 - 3.9 7.8 7.2 1.5 9.2 0.5 3.0 3 1 1 4 4 4 0 Phage T7 capsid assembly protein Spc7 PF08317.11 OEU15158.1 - 0.038 12.9 1.0 0.057 12.3 1.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mt_ATP-synt_D PF05873.12 OEU15158.1 - 0.058 13.3 0.2 0.091 12.6 0.2 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) CP12 PF02672.15 OEU15158.1 - 0.17 12.7 0.6 0.39 11.5 0.6 1.6 1 0 0 1 1 1 0 CP12 domain WD40 PF00400.32 OEU15159.1 - 7e-10 39.3 13.9 2.6 9.0 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU15159.1 - 0.00012 22.3 0.0 0.16 12.3 0.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 OEU15159.1 - 0.037 13.3 0.2 0.39 10.0 0.0 2.6 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Utp21 PF04192.12 OEU15160.1 - 8.4e-05 22.2 0.8 0.00014 21.4 0.8 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain DUF3560 PF12083.8 OEU15160.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Afi1 PF07792.12 OEU15160.1 - 0.058 13.9 0.7 0.075 13.5 0.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PIG-U PF06728.13 OEU15161.1 - 4e-26 92.0 18.4 4.7e-26 91.7 18.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Sec62 PF03839.16 OEU15162.1 - 2.5e-24 86.0 7.0 2.5e-24 86.0 7.0 1.9 2 1 0 2 2 2 1 Translocation protein Sec62 SAC3_GANP PF03399.16 OEU15163.1 - 4.8e-20 72.1 0.6 4.8e-20 72.1 0.6 1.5 2 0 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OEU15163.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Heme_oxygenase PF01126.20 OEU15164.1 - 5.4e-11 42.7 0.1 7.2e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Heme oxygenase DUF4688 PF15752.5 OEU15164.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) FAD_binding_7 PF03441.14 OEU15165.1 - 4.5e-56 189.5 0.0 1.3e-55 188.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OEU15165.1 - 4.9e-28 98.2 0.0 1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase HtrL_YibB PF09612.10 OEU15166.1 - 3.1e-14 53.1 1.1 5.2e-14 52.4 1.1 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) PRMT5 PF05185.16 OEU15167.1 - 1.5e-56 191.0 0.0 2e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OEU15167.1 - 1.2e-39 136.1 0.2 2.2e-39 135.1 0.2 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 OEU15167.1 - 0.002 17.9 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Thioredoxin PF00085.20 OEU15169.1 - 1.3e-05 25.1 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 OEU15169.1 - 5.4e-05 22.3 0.1 7.7e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Phosducin TraF PF13728.6 OEU15169.1 - 0.00012 22.0 0.1 0.00026 20.9 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 OEU15169.1 - 0.012 16.0 0.0 0.039 14.4 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain RVT_connect PF06815.13 OEU15169.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase connection domain DUF2358 PF10184.9 OEU15170.1 - 5.5e-15 55.6 0.0 1.9e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SOUL PF04832.12 OEU15170.1 - 4.7e-14 52.9 0.0 1.8e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 SOUL heme-binding protein Phage_spike_2 PF18781.1 OEU15170.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Phage spike trimer SnoaL_2 PF12680.7 OEU15170.1 - 0.17 12.5 0.0 0.43 11.2 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain COX7a PF02238.15 OEU15171.1 - 0.065 13.7 1.1 0.082 13.3 0.1 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII 2-oxoacid_dh PF00198.23 OEU15172.1 - 1.4e-58 198.1 0.1 1.5e-58 198.0 0.1 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IQ PF00612.27 OEU15173.1 - 1.6e-62 201.5 260.8 0.0043 16.7 0.0 49.7 52 0 0 52 52 52 36 IQ calmodulin-binding motif DUF3562 PF12085.8 OEU15173.1 - 0.17 11.5 5.7 28 4.4 0.1 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3562) Thymidylate_kin PF02223.17 OEU15173.1 - 1.9 8.1 10.1 2.1 8.0 1.2 3.3 2 0 0 2 2 2 0 Thymidylate kinase XPG_N PF00752.17 OEU15174.1 - 8.2e-11 42.3 0.0 2e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OEU15174.1 - 9.5e-09 35.5 0.1 5e-08 33.2 0.1 2.4 1 1 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OEU15174.1 - 0.00036 20.1 0.8 0.00086 18.9 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing zf-CHY PF05495.12 OEU15175.1 - 5.7e-15 55.6 12.7 5.7e-15 55.6 12.7 4.9 2 2 0 2 2 1 1 CHY zinc finger zinc_ribbon_6 PF14599.6 OEU15175.1 - 2.8e-14 52.9 0.1 2.8e-14 52.9 0.1 3.8 3 2 1 4 4 3 1 Zinc-ribbon zf-RING_2 PF13639.6 OEU15175.1 - 2.4e-08 34.2 8.4 2.4e-08 34.2 8.4 5.7 5 2 0 5 5 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 OEU15175.1 - 7.7e-06 25.6 7.2 7.7e-06 25.6 7.2 5.7 5 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU15175.1 - 1.2e-05 25.2 7.1 1.2e-05 25.2 7.1 6.0 3 2 3 6 6 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU15175.1 - 0.00021 21.3 1.5 0.00021 21.3 1.5 5.9 5 1 1 6 6 6 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU15175.1 - 0.00038 20.2 6.7 0.00038 20.2 6.7 5.9 3 2 2 5 5 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU15175.1 - 0.0017 18.2 3.1 0.0017 18.2 3.1 5.8 3 2 2 6 6 5 1 Prokaryotic RING finger family 4 Ribosomal_L40e PF01020.17 OEU15175.1 - 0.019 14.9 0.8 0.019 14.9 0.8 2.7 2 0 0 2 2 2 0 Ribosomal L40e family zf-WRNIP1_ubi PF18279.1 OEU15175.1 - 0.19 12.4 8.2 4.2 8.2 0.0 4.5 4 1 0 4 4 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DNA_ligase_ZBD PF03119.16 OEU15175.1 - 0.46 10.5 8.9 20 5.3 0.1 4.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Rad50_zn_hook PF04423.14 OEU15175.1 - 9 6.2 10.5 1.8 8.5 0.3 3.5 4 0 0 4 4 4 0 Rad50 zinc hook motif FoP_duplication PF13865.6 OEU15177.1 - 1.2e-15 57.8 14.8 1.2e-15 57.8 14.8 2.9 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 GP38 PF05268.11 OEU15177.1 - 8.4 6.0 14.2 11 5.6 14.2 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Nkap_C PF06047.11 OEU15178.1 - 1.7e-45 153.3 0.8 2.1e-45 153.0 0.8 1.1 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Gyro_capsid PF04162.12 OEU15178.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Cyclin_N PF00134.23 OEU15179.1 - 3e-09 36.7 0.1 3.7e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OEU15179.1 - 9.1e-09 35.9 0.1 1.1e-08 35.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OEU15180.1 - 3.6e-07 30.0 0.1 5.3e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OEU15180.1 - 2.5e-05 24.7 0.1 3.1e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin PseudoU_synth_2 PF00849.22 OEU15181.1 - 1.8e-13 50.9 0.1 8.1e-13 48.8 0.1 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase UL42 PF17638.2 OEU15182.1 - 0.35 10.9 6.6 1.1 9.3 6.6 1.8 1 0 0 1 1 1 0 HCMV UL42 DTC PF18102.1 OEU15185.1 - 5.2e-19 68.7 0.0 1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Deltex C-terminal domain zf-rbx1 PF12678.7 OEU15185.1 - 0.00011 22.4 2.9 0.00011 22.4 2.9 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OEU15185.1 - 0.0011 19.2 3.7 0.0011 19.2 3.7 3.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU15185.1 - 0.0015 18.4 0.9 0.0015 18.4 0.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU15185.1 - 0.0016 18.5 0.5 0.0016 18.5 0.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OEU15185.1 - 0.012 15.6 3.0 0.012 15.6 3.0 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_11 PF17123.5 OEU15185.1 - 0.013 15.3 2.4 0.031 14.0 0.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OEU15185.1 - 0.048 13.7 2.9 0.17 12.0 2.9 2.0 1 0 0 1 1 1 0 RING-type zinc-finger HrpA_pilin PF09589.10 OEU15186.1 - 0.0037 17.9 4.5 0.013 16.1 4.5 1.9 1 0 0 1 1 1 1 HrpA pilus formation protein SMAP PF15477.6 OEU15186.1 - 0.73 10.8 0.1 0.73 10.8 0.1 2.9 3 1 0 3 3 3 0 Small acidic protein family Thioredoxin_8 PF13905.6 OEU15187.1 - 2.4e-09 37.4 0.7 9.8e-09 35.4 0.4 2.1 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.20 OEU15187.1 - 3e-06 27.1 0.6 0.00012 22.0 0.2 2.5 1 1 1 2 2 2 1 Thioredoxin Calmodulin_bind PF07887.11 OEU15187.1 - 0.0028 17.0 0.2 0.0037 16.6 0.2 1.3 1 0 0 1 1 1 1 Calmodulin binding protein-like AhpC-TSA PF00578.21 OEU15187.1 - 0.0053 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family AKAP95 PF04988.12 OEU15187.1 - 0.014 15.6 0.9 0.024 14.9 0.9 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Thioredoxin_2 PF13098.6 OEU15187.1 - 0.02 15.3 0.3 0.055 13.9 0.3 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1676 PF07898.13 OEU15187.1 - 0.34 10.9 2.3 0.75 9.8 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1676) EF-hand_6 PF13405.6 OEU15188.1 - 9e-06 25.2 0.8 0.0065 16.3 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU15188.1 - 2e-05 24.9 0.4 3.2e-05 24.3 0.4 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU15188.1 - 5.2e-05 22.5 0.1 0.0063 16.0 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OEU15188.1 - 0.017 14.6 0.8 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 OEU15188.1 - 0.028 14.3 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Aminotran_1_2 PF00155.21 OEU15189.1 - 4e-37 128.2 0.0 5.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_16 PF10294.9 OEU15191.1 - 1.2e-23 83.7 0.0 2.2e-23 82.9 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 OEU15191.1 - 2.8e-05 24.0 0.0 9.3e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU15191.1 - 0.00031 20.4 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OEU15191.1 - 0.00058 19.7 0.0 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU15191.1 - 0.0025 18.5 0.0 0.012 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OEU15191.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 OEU15191.1 - 0.021 15.5 0.0 0.046 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 OEU15191.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 LSM domain DUF4662 PF15578.6 OEU15192.1 - 0.00062 19.7 2.4 0.00088 19.1 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4662) Menin PF05053.13 OEU15193.1 - 1.9 6.7 10.1 2.1 6.6 10.1 1.0 1 0 0 1 1 1 0 Menin CSN5_C PF18323.1 OEU15193.1 - 2.1 9.3 16.0 4.8 8.2 1.2 2.3 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Ribosomal_S8 PF00410.19 OEU15194.1 - 2.1e-23 82.6 0.0 3.4e-23 82.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L35Ae PF01247.18 OEU15195.1 - 3e-38 129.9 0.1 3.3e-38 129.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OEU15195.1 - 0.057 13.6 0.4 14 6.0 0.1 2.5 2 1 0 2 2 2 0 RimM N-terminal domain zf-RING_UBOX PF13445.6 OEU15196.1 - 7e-06 26.0 3.0 1e-05 25.5 2.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU15196.1 - 0.0001 22.6 11.1 0.00026 21.3 11.1 1.8 1 1 0 1 1 1 1 Ring finger domain PDZ_2 PF13180.6 OEU15196.1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain zf-RING_4 PF14570.6 OEU15196.1 - 0.00034 20.4 12.0 0.0015 18.3 12.0 2.1 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OEU15196.1 - 0.0077 16.4 14.9 0.077 13.2 14.9 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OEU15196.1 - 0.037 13.9 9.9 0.13 12.2 9.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ_6 PF17820.1 OEU15196.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain IBR PF01485.21 OEU15196.1 - 1.2 9.4 14.7 0.63 10.3 9.0 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 OEU15196.1 - 3.5 7.8 11.9 4.2 7.6 9.9 2.2 2 1 0 2 2 2 0 FYVE zinc finger zf-C3HC4_2 PF13923.6 OEU15196.1 - 6.3 6.7 11.7 1.2 9.0 6.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 OEU15197.1 - 5.2e-07 29.7 12.1 1.9e-06 27.9 12.1 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OEU15197.1 - 0.0051 16.9 20.8 0.01 15.8 20.8 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 OEU15197.1 - 0.01 15.2 11.4 0.017 14.5 6.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_28 PF13521.6 OEU15197.1 - 0.015 15.5 0.9 2 8.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 OEU15197.1 - 0.033 13.1 12.1 0.056 12.4 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TMEM247 PF15444.6 OEU15197.1 - 2.1 8.4 6.8 17 5.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 TERB2 PF15101.6 OEU15197.1 - 4.7 7.2 11.9 0.95 9.5 8.0 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 HMG_box PF00505.19 OEU15198.1 - 3.1e-07 30.7 0.1 0.025 15.0 0.0 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU15198.1 - 1.2e-06 29.1 1.1 0.023 15.3 0.0 3.0 3 0 0 3 3 3 2 HMG-box domain YABBY PF04690.13 OEU15198.1 - 0.0072 16.9 4.0 0.016 15.8 4.0 1.7 1 1 0 1 1 1 1 YABBY protein Macoilin PF09726.9 OEU15198.1 - 0.049 12.2 11.4 0.053 12.1 11.4 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 OEU15198.1 - 0.44 8.8 6.6 0.54 8.5 6.6 1.1 1 0 0 1 1 1 0 Menin PI3K_1B_p101 PF10486.9 OEU15198.1 - 0.58 7.9 4.8 0.62 7.8 4.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Caskin1-CID PF16600.5 OEU15198.1 - 4.4 8.0 7.2 1.1 9.9 3.3 1.9 1 1 1 2 2 2 0 Caskin1 CASK-interaction domain CTP_synth_N PF06418.14 OEU15199.1 - 4.8e-124 412.9 0.1 6.4e-124 412.5 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OEU15199.1 - 3.2e-50 170.6 0.0 4.8e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OEU15199.1 - 0.0015 18.4 0.0 0.011 15.5 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 OEU15199.1 - 0.0026 17.8 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ComX PF05952.12 OEU15199.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX MeaB PF03308.16 OEU15199.1 - 0.13 11.2 0.4 0.22 10.5 0.4 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HMG_box PF00505.19 OEU15200.1 - 2.1e-09 37.6 0.5 0.00018 21.8 0.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU15200.1 - 1.5e-07 31.9 1.3 0.0029 18.2 0.2 2.8 2 0 0 2 2 2 2 HMG-box domain Peptidase_M41 PF01434.18 OEU15202.1 - 0.0011 18.8 0.8 0.0092 15.8 0.2 2.6 1 1 1 2 2 2 1 Peptidase family M41 Viral_P18 PF04521.13 OEU15202.1 - 0.17 11.6 0.1 0.45 10.3 0.1 1.8 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein LSM PF01423.22 OEU15205.1 - 1.1e-18 66.6 0.4 1.5e-18 66.2 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OEU15205.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF1115 PF06544.12 OEU15206.1 - 2.6e-07 30.8 0.0 8.8e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 OEU15206.1 - 0.00076 19.8 0.0 0.057 13.7 0.0 2.5 1 1 0 1 1 1 1 RWD domain MFS_5 PF05631.14 OEU15207.1 - 2.4e-85 286.5 9.6 4.7e-85 285.6 9.6 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OEU15207.1 - 5e-21 75.0 36.1 5.3e-18 65.1 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 OEU15207.1 - 0.73 10.3 3.5 7.1 7.1 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) NAD_binding_1 PF00175.21 OEU15208.1 - 1e-23 84.0 0.0 1.9e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 OEU15208.1 - 0.2 11.2 0.0 2 8.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Mito_carr PF00153.27 OEU15209.1 - 9.2e-19 67.2 3.8 6.3e-06 26.0 0.1 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3672 PF12421.8 OEU15209.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Fibronectin type III protein ADH_N PF08240.12 OEU15210.1 - 3.5e-15 55.8 2.0 4.9e-14 52.1 2.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OEU15210.1 - 4.6e-09 36.3 0.0 9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OEU15210.1 - 0.00082 18.9 0.0 0.0021 17.6 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OEU15210.1 - 0.014 16.4 0.0 3.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Zinc-binding dehydrogenase DnaJ PF00226.31 OEU15211.1 - 1.2e-13 51.0 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain TALPID3 PF15324.6 OEU15211.1 - 0.095 10.4 1.4 0.11 10.2 1.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Herpes_UL4 PF03277.13 OEU15211.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family PCO_ADO PF07847.12 OEU15212.1 - 2.9e-34 118.3 0.2 2e-33 115.6 0.0 2.1 2 0 0 2 2 2 1 PCO_ADO SPX PF03105.19 OEU15212.1 - 5.5 6.8 21.3 2.7 7.8 5.4 2.2 2 0 0 2 2 2 0 SPX domain ABC_tran PF00005.27 OEU15214.1 - 4.3e-47 160.1 0.4 6.3e-25 88.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU15214.1 - 8.5e-17 61.9 0.3 0.0048 16.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OEU15214.1 - 8.6e-15 54.5 0.5 8.6e-15 54.5 0.5 1.6 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 OEU15214.1 - 7.7e-13 48.4 0.7 0.00065 19.2 0.2 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OEU15214.1 - 2.7e-09 36.6 0.7 0.0016 18.1 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU15214.1 - 1.8e-07 31.9 4.6 0.0047 17.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OEU15214.1 - 2.5e-05 24.3 0.2 0.083 12.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 OEU15214.1 - 2.7e-05 23.9 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 OEU15214.1 - 6.8e-05 22.0 0.1 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OEU15214.1 - 7.9e-05 22.5 2.8 0.16 11.7 0.2 3.2 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OEU15214.1 - 8.9e-05 22.6 1.4 0.087 12.9 0.4 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OEU15214.1 - 0.00012 22.5 0.2 0.023 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OEU15214.1 - 0.00016 22.2 0.1 0.2 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU15214.1 - 0.00041 20.5 0.1 0.09 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OEU15214.1 - 0.00075 19.8 0.1 0.088 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OEU15214.1 - 0.005 16.1 0.0 0.45 9.6 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.6 OEU15214.1 - 0.0091 15.7 2.7 0.52 10.0 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain cobW PF02492.19 OEU15214.1 - 0.0097 15.5 0.2 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OEU15214.1 - 0.01 15.9 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 OEU15214.1 - 0.019 14.9 0.9 1.9 8.4 0.0 2.7 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.6 OEU15214.1 - 0.02 15.1 0.6 3.6 7.8 0.0 2.8 2 1 1 3 3 2 0 AAA domain Arf PF00025.21 OEU15214.1 - 0.026 14.0 0.1 1.4 8.3 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family T2SSE PF00437.20 OEU15214.1 - 0.028 13.5 0.0 0.55 9.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 OEU15214.1 - 0.029 14.1 0.0 0.96 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OEU15214.1 - 0.037 13.2 0.2 0.65 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 OEU15214.1 - 0.04 13.3 1.6 0.075 12.4 0.0 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 OEU15214.1 - 0.046 14.1 0.0 4.5 7.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 OEU15214.1 - 0.054 12.3 0.7 4.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 OEU15214.1 - 0.07 13.5 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.6 OEU15214.1 - 0.076 11.7 0.0 6.2 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OEU15214.1 - 0.082 12.6 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein G-alpha PF00503.20 OEU15214.1 - 0.12 11.5 0.0 0.62 9.2 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 OEU15214.1 - 0.14 12.2 0.0 9.9 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 OEU15214.1 - 0.14 11.7 0.1 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU15214.1 - 0.18 11.3 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1769 PF08588.10 OEU15215.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CLP_protease PF00574.23 OEU15216.1 - 5.4e-80 267.6 0.0 6.1e-80 267.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease PurA PF04845.13 OEU15216.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein Methyltransf_16 PF10294.9 OEU15217.1 - 3.2e-05 23.7 2.1 0.12 12.1 0.2 2.7 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 OEU15217.1 - 0.00076 19.3 0.1 0.0023 17.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU15217.1 - 4.1 8.2 9.9 26 5.7 4.1 4.0 2 2 0 2 2 2 0 Methyltransferase domain Spindle_Spc25 PF08234.12 OEU15218.1 - 0.0042 17.2 0.5 0.0095 16.1 0.1 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF1421 PF07223.11 OEU15218.1 - 0.36 10.7 1.0 7.1 6.5 0.0 2.6 3 0 0 3 3 3 0 UBA-like domain (DUF1421) TatD_DNase PF01026.21 OEU15219.1 - 3.6e-18 65.9 0.1 2.7e-13 49.9 0.1 2.2 2 0 0 2 2 2 2 TatD related DNase EIF_2_alpha PF07541.12 OEU15219.1 - 0.021 14.9 0.1 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit ODV-E18 PF10717.9 OEU15220.1 - 0.00086 19.1 0.1 0.0027 17.5 0.1 1.8 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Mucin PF01456.17 OEU15220.1 - 0.02 14.9 2.9 0.032 14.2 0.1 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Phytochelatin PF05023.14 OEU15221.1 - 1.2e-36 126.0 0.0 1.7e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase EamA PF00892.20 OEU15222.1 - 1.2e-19 70.8 31.0 4.5e-17 62.5 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family HupE_UreJ PF04955.12 OEU15222.1 - 0.01 15.3 2.4 0.011 15.2 0.3 2.0 2 0 0 2 2 2 0 HupE / UreJ protein Bmt2 PF11968.8 OEU15223.1 - 6.9e-32 111.1 7.1 4.3e-19 69.2 0.0 3.0 3 1 0 3 3 3 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Abhydrolase_1 PF00561.20 OEU15224.1 - 2.2e-22 79.9 0.1 7.3e-21 75.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU15224.1 - 7.2e-11 41.8 0.0 1.7e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU15224.1 - 6.1e-06 27.0 0.0 1e-05 26.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OEU15224.1 - 0.0016 18.0 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OEU15224.1 - 0.045 13.5 0.0 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 OEU15224.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1837 PF08878.11 OEU15224.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Cyto_heme_lyase PF01265.17 OEU15225.1 - 2e-38 132.7 9.9 1.6e-19 70.6 1.0 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase NADH_dhqG_C PF09326.11 OEU15225.1 - 0.018 15.7 0.1 0.032 14.9 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal LssY_C PF14067.6 OEU15225.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 LssY C-terminus dCache_1 PF02743.18 OEU15226.1 - 3.4e-11 43.4 7.5 7.4e-05 22.7 0.3 3.4 2 1 1 3 3 3 2 Cache domain VWA_3 PF13768.6 OEU15226.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain MatE PF01554.18 OEU15227.1 - 7e-22 77.8 20.1 5.6e-18 65.1 5.2 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU15227.1 - 3.1e-09 37.0 0.3 3.1e-09 37.0 0.3 4.3 3 1 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Tir_receptor_C PF07489.11 OEU15227.1 - 0.053 13.5 8.7 0.11 12.5 8.7 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TMEM154 PF15102.6 OEU15227.1 - 6.6 6.6 11.9 42 4.0 9.3 2.8 3 0 0 3 3 3 0 TMEM154 protein family Aminotran_1_2 PF00155.21 OEU15228.1 - 3.3e-24 85.7 0.0 4.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SH2_2 PF14633.6 OEU15231.1 - 0.018 14.4 0.1 0.021 14.2 0.1 1.0 1 0 0 1 1 1 0 SH2 domain Bee_toxin PF17454.2 OEU15231.1 - 0.2 11.7 0.3 0.38 10.8 0.3 1.5 1 0 0 1 1 1 0 Honey bee toxin Na_Ca_ex PF01699.24 OEU15232.1 - 2.6e-40 137.8 37.2 4.6e-22 78.6 14.9 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Haemadin PF09065.10 OEU15232.1 - 0.027 14.2 0.1 0.067 13.0 0.1 1.7 1 0 0 1 1 1 0 Haemadin Kinesin PF00225.23 OEU15233.1 - 6.8e-98 327.7 0.6 8.5e-98 327.3 0.6 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU15233.1 - 1.5e-22 80.1 0.1 3.9e-22 78.8 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 OEU15233.1 - 0.011 15.5 0.7 0.044 13.6 0.2 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2206 PF09971.9 OEU15234.1 - 1.2 7.8 4.6 0.39 9.4 0.1 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2206) DUF1349 PF07081.11 OEU15235.1 - 2.8e-54 183.5 0.8 3.1e-54 183.4 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 OEU15235.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1349 PF07081.11 OEU15236.1 - 7.7e-47 159.3 0.1 8.5e-47 159.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 OEU15236.1 - 1.7e-05 24.6 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Helicase_C PF00271.31 OEU15237.1 - 9.2e-13 48.5 0.1 9.1e-12 45.3 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 OEU15239.1 - 2.7e-14 53.3 16.0 8.5e-05 23.2 0.1 6.2 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 OEU15239.1 - 1.2e-08 34.5 10.8 0.00041 20.3 0.1 5.4 5 0 0 5 5 4 2 HEAT repeat HEAT_2 PF13646.6 OEU15239.1 - 1.2e-05 25.6 1.1 0.0032 17.8 0.2 3.8 2 1 1 3 3 3 1 HEAT repeats Tti2 PF10521.9 OEU15239.1 - 0.00016 21.3 0.1 0.00053 19.6 0.0 1.8 2 0 0 2 2 2 1 Tti2 family Pkinase PF00069.25 OEU15239.1 - 0.00062 19.2 0.0 0.0024 17.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Vac14_Fab1_bd PF12755.7 OEU15239.1 - 0.0014 19.1 0.0 0.016 15.8 0.0 2.4 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OEU15239.1 - 0.0029 16.2 0.2 0.15 10.6 0.3 2.2 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 OEU15239.1 - 0.0086 16.1 0.0 4.9 7.2 0.1 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OEU15239.1 - 0.015 15.5 0.2 0.13 12.5 0.1 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3717 PF12512.8 OEU15239.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) HEAT_EZ PF13513.6 OEU15239.1 - 0.036 14.6 0.2 0.69 10.5 0.1 3.0 2 0 0 2 2 2 0 HEAT-like repeat DUF4529 PF15032.6 OEU15239.1 - 0.046 12.8 0.4 0.09 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) ANAPC4_WD40 PF12894.7 OEU15239.1 - 0.14 12.5 0.1 11 6.4 0.0 3.3 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain peroxidase PF00141.23 OEU15240.1 - 7.5e-76 254.8 0.0 4.8e-41 141.0 0.0 2.4 2 1 0 2 2 2 2 Peroxidase SatRNA_48 PF17485.2 OEU15240.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein GDH_N PF12466.8 OEU15240.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal PT PF04886.12 OEU15241.1 - 0.023 14.2 17.3 21 4.7 17.3 3.0 1 1 0 1 1 1 0 PT repeat DUF3867 PF12983.7 OEU15242.1 - 0.1 12.6 5.5 0.71 9.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) HS1_rep PF02218.15 OEU15243.1 - 0.11 12.8 0.3 0.21 11.9 0.3 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin DUF1295 PF06966.12 OEU15245.1 - 1.4e-29 103.3 6.0 2.1e-29 102.7 5.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) MFS_1 PF07690.16 OEU15246.1 - 6.2e-15 55.0 11.3 6.2e-15 55.0 11.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OEU15246.1 - 9e-07 27.6 1.9 1e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FAM176 PF14851.6 OEU15246.1 - 6 6.5 7.3 7.2 6.3 0.0 3.5 4 0 0 4 4 4 0 FAM176 family Asn_synthase PF00733.21 OEU15247.1 - 9.7e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 1 0 1 1 1 1 Asparagine synthase F_bP_aldolase PF01116.20 OEU15248.1 - 1.4e-84 283.9 0.0 1.6e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Aa_trans PF01490.18 OEU15249.1 - 1.5e-49 168.9 19.2 1.9e-49 168.5 19.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sulfotransfer_2 PF03567.14 OEU15250.1 - 7.9e-20 71.8 3.6 1.5e-19 70.9 3.6 1.4 1 0 0 1 1 1 1 Sulfotransferase family CrgA PF06781.12 OEU15250.1 - 0.04 14.0 0.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Cell division protein CrgA DUF4506 PF14958.6 OEU15251.1 - 0.0027 17.2 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) TnpV PF14198.6 OEU15251.1 - 0.14 12.1 5.1 3.2 7.8 0.2 3.0 2 0 0 2 2 2 0 Transposon-encoded protein TnpV ptaRNA1_toxin PF12703.7 OEU15251.1 - 0.17 11.9 1.5 0.35 11.0 0.1 2.2 3 0 0 3 3 3 0 Toxin of toxin-antitoxin type 1 system SUIM_assoc PF16619.5 OEU15251.1 - 0.23 11.5 9.7 0.12 12.4 4.3 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cpn60_TCP1 PF00118.24 OEU15252.1 - 1.2e-132 443.1 13.8 1.3e-132 442.9 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GAGE PF05831.11 OEU15252.1 - 0.16 12.5 0.0 4.2 7.9 0.0 2.4 2 0 0 2 2 2 0 GAGE protein Peptidase_S8 PF00082.22 OEU15254.1 - 7.9e-32 110.7 0.7 1.3e-31 110.0 0.7 1.3 1 0 0 1 1 1 1 Subtilase family DUF262 PF03235.14 OEU15255.1 - 4.7e-15 56.4 0.3 1.3e-14 54.9 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF262 ETC_C1_NDUFA5 PF04716.14 OEU15256.1 - 2.5e-10 40.0 0.0 3.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region FATC PF02260.20 OEU15256.1 - 1 9.2 4.0 20 5.1 1.2 2.8 2 1 1 3 3 3 0 FATC domain Beta_helix PF13229.6 OEU15257.1 - 4.4e-11 42.9 4.4 4.4e-11 42.9 4.4 2.1 2 1 0 2 2 2 1 Right handed beta helix region F-box-like PF12937.7 OEU15257.1 - 0.00068 19.5 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like Membralin PF09746.9 OEU15257.1 - 0.18 10.8 2.3 0.39 9.7 2.3 1.4 1 0 0 1 1 1 0 Tumour-associated protein NosD PF05048.13 OEU15257.1 - 0.52 9.5 11.7 0.058 12.7 5.2 2.6 2 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Suf PF05843.14 OEU15257.1 - 0.55 10.2 8.0 1.2 9.0 8.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt5_N PF11942.8 OEU15257.1 - 0.64 11.0 11.3 2.1 9.4 3.5 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Macoilin PF09726.9 OEU15257.1 - 1.9 7.0 15.1 0.065 11.8 7.0 1.9 2 0 0 2 2 2 0 Macoilin family DUF4834 PF16118.5 OEU15257.1 - 2.1 9.3 4.9 1 10.4 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 OEU15257.1 - 4 6.2 10.2 8.9 5.0 10.2 1.5 1 0 0 1 1 1 0 Androgen receptor AF-4 PF05110.13 OEU15257.1 - 4.8 5.1 25.6 0.16 10.0 19.6 1.5 2 0 0 2 2 2 0 AF-4 proto-oncoprotein p450 PF00067.22 OEU15258.1 - 3.2e-72 243.7 0.0 4.6e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OEU15258.1 - 3.5e-26 92.2 0.0 6.6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OEU15258.1 - 1.1e-21 77.6 0.0 2.2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OEU15258.1 - 2.7e-19 69.8 0.1 1.6e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OEU15258.1 - 0.0016 18.7 0.0 0.0054 17.0 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Band_7 PF01145.25 OEU15259.1 - 1.2e-27 97.1 1.2 3e-27 95.8 0.5 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4290 PF14123.6 OEU15259.1 - 0.085 12.4 0.6 0.13 11.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) T6SS_HCP PF05638.12 OEU15260.1 - 0.01 16.3 0.0 0.35 11.3 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system effector, Hcp GP38 PF05268.11 OEU15260.1 - 0.15 11.7 1.9 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 LRR_8 PF13855.6 OEU15262.1 - 5.6e-25 86.9 34.1 1.3e-07 31.2 0.2 6.8 3 3 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OEU15262.1 - 1.6e-20 72.8 35.4 0.0026 18.1 1.9 8.7 3 2 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU15262.1 - 1.5e-09 37.0 26.5 0.45 11.3 0.0 11.9 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU15262.1 - 0.31 11.2 28.5 7.8 6.8 0.0 8.9 10 0 0 10 10 10 0 Leucine Rich repeat LRR_9 PF14580.6 OEU15262.1 - 0.31 10.5 6.7 6.2 6.3 0.4 3.6 1 1 4 5 5 5 0 Leucine-rich repeat LRR_8 PF13855.6 OEU15263.1 - 1.8e-16 59.6 36.7 1.1e-08 34.7 3.8 5.4 2 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OEU15263.1 - 1.9e-11 44.0 35.1 0.0037 17.6 0.3 6.2 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU15263.1 - 1.1e-06 28.4 24.1 3.9 8.4 0.0 9.2 7 3 1 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU15263.1 - 8.6 6.7 31.2 13 6.2 0.2 8.9 10 0 0 10 10 10 0 Leucine Rich repeat AP_endonuc_2 PF01261.24 OEU15264.1 - 0.0016 17.9 0.0 0.015 14.7 0.0 2.1 1 1 0 2 2 2 1 Xylose isomerase-like TIM barrel Semialdhyde_dh PF01118.24 OEU15265.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 OEU15265.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TraB PF01963.17 OEU15266.1 - 4.9e-17 62.7 0.1 2.9e-09 37.2 0.0 2.6 1 1 1 2 2 2 2 TraB family GCIP PF13324.6 OEU15266.1 - 0.089 12.4 5.6 0.19 11.3 4.4 1.9 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting KCNQ2_u3 PF16642.5 OEU15266.1 - 0.13 13.3 0.7 0.13 13.3 0.7 3.3 3 0 0 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 SPT6_acidic PF14632.6 OEU15266.1 - 0.28 11.8 7.3 0.84 10.3 7.3 1.8 1 0 0 1 1 1 0 Acidic N-terminal SPT6 MaoC_dehydrat_N PF13452.6 OEU15267.1 - 0.031 14.4 0.0 4.6 7.4 0.0 2.8 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase DUF3006 PF11213.8 OEU15267.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) FAM212 PF15342.6 OEU15268.1 - 1.9e-09 37.2 12.0 0.038 13.8 0.1 6.6 5 0 0 5 5 5 4 FAM212 family CLZ PF16526.5 OEU15268.1 - 0.08 13.3 21.0 0.16 12.4 3.0 3.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 OEU15268.1 - 4.9 7.2 9.3 1.7 8.7 5.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_8 PF13181.6 OEU15269.1 - 0.00084 19.4 2.4 4.1 7.9 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU15269.1 - 0.024 14.3 0.9 0.25 11.0 0.0 3.1 4 0 0 4 4 4 0 TPR repeat zf-LITAF-like PF10601.9 OEU15270.1 - 1.2e-14 54.3 5.2 1.6e-14 53.9 5.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DZR PF12773.7 OEU15270.1 - 0.0015 18.5 1.0 0.21 11.6 0.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU15270.1 - 0.0021 17.7 3.6 0.23 11.3 0.3 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Nudix_N_2 PF14803.6 OEU15270.1 - 0.017 15.1 2.4 3.9 7.5 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal NOB1_Zn_bind PF08772.11 OEU15270.1 - 0.026 14.7 1.2 5.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 OEU15270.1 - 0.042 13.3 2.0 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OEU15270.1 - 0.087 12.8 1.1 7.7 6.5 0.2 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RecR PF02132.15 OEU15270.1 - 0.11 12.1 2.7 3.8 7.1 0.1 2.2 2 0 0 2 2 2 0 RecR protein Zn_Tnp_IS1595 PF12760.7 OEU15270.1 - 0.17 11.9 2.2 0.96 9.5 0.3 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RRN7 PF11781.8 OEU15270.1 - 0.41 10.4 6.0 1.4 8.7 1.9 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 OEU15270.1 - 0.46 10.7 3.0 6.8 6.9 0.2 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RanBP PF00641.18 OEU15270.1 - 3.8 6.9 10.2 1.8 7.9 0.8 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others TPR_3 PF07720.12 OEU15271.1 - 0.035 14.1 0.2 0.085 12.9 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU15271.1 - 0.084 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5363 PF17320.2 OEU15271.1 - 0.13 12.2 0.7 0.36 10.7 0.1 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5363) HAD_2 PF13419.6 OEU15272.1 - 3.2e-15 56.7 0.1 4.9e-15 56.1 0.1 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU15272.1 - 1.7e-11 44.8 0.0 1.5e-10 41.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU15272.1 - 4.4e-05 24.0 0.0 5.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 OEU15272.1 - 0.0039 17.0 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase MgtE_N PF03448.17 OEU15272.1 - 0.029 15.0 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain DUF3994 PF13159.6 OEU15272.1 - 0.059 13.9 0.0 0.19 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) TPR_12 PF13424.6 OEU15273.1 - 6.9e-44 148.0 27.1 2.7e-17 62.8 0.8 6.0 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 OEU15273.1 - 6.4e-41 137.1 16.4 6.7e-09 35.3 0.3 6.9 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15273.1 - 3.6e-20 70.9 15.8 1.7e-05 24.4 0.4 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU15273.1 - 1.6e-19 68.4 15.5 1.8e-05 24.5 0.3 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU15273.1 - 5.8e-17 60.4 18.0 0.00011 21.9 0.1 6.6 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15273.1 - 1.3e-16 59.4 16.4 0.00048 20.1 0.4 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 OEU15273.1 - 3.1e-11 42.9 5.8 0.26 11.8 0.0 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OEU15273.1 - 8.2e-11 42.4 0.5 0.011 16.4 0.0 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.9 OEU15273.1 - 4.5e-08 33.1 4.7 0.0019 18.0 0.2 3.3 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 OEU15273.1 - 5.4e-08 32.9 1.4 0.046 13.9 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU15273.1 - 1.9e-07 30.8 9.1 4.5e-07 29.6 9.1 1.6 1 1 0 1 1 1 1 MalT-like TPR region SNAP PF14938.6 OEU15273.1 - 6.7e-07 29.0 3.2 0.0024 17.3 0.4 2.4 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 OEU15273.1 - 1.2e-06 28.8 6.1 8.5 7.5 0.0 5.9 5 1 2 7 7 6 0 Tetratricopeptide repeat DUF2753 PF10952.8 OEU15273.1 - 4.1e-05 23.7 1.0 0.031 14.4 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF2753) DUF3856 PF12968.7 OEU15273.1 - 6.3e-05 23.1 3.5 0.014 15.4 0.2 3.4 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 OEU15273.1 - 8.7e-05 22.1 13.2 0.077 12.7 1.1 7.0 6 2 2 8 8 8 1 TPR repeat TPR_6 PF13174.6 OEU15273.1 - 0.00017 22.0 8.8 1.2 10.0 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU15273.1 - 0.00035 20.2 3.1 0.093 12.2 0.5 2.6 1 1 1 2 2 2 2 Meiosis protein SPO22/ZIP4 like DUF4404 PF14357.6 OEU15273.1 - 0.00067 20.2 2.4 1.6 9.4 0.2 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4404) Vta1_C PF18097.1 OEU15273.1 - 0.00089 18.9 2.5 0.48 10.2 0.2 4.2 4 0 0 4 4 4 1 Vta1 C-terminal domain BTAD PF03704.17 OEU15273.1 - 0.0014 19.1 8.0 1.8 9.0 0.1 4.6 2 1 3 5 5 5 2 Bacterial transcriptional activator domain MIT PF04212.18 OEU15273.1 - 0.0015 18.5 6.8 20 5.4 0.0 5.3 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain ATG16 PF08614.11 OEU15273.1 - 0.0023 18.2 2.6 0.013 15.8 1.6 2.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF5113 PF17140.4 OEU15273.1 - 0.0086 15.9 8.4 0.28 11.0 0.1 4.2 2 2 3 5 5 5 1 Domain of unknown function (DUF5113) TPR_15 PF13429.6 OEU15273.1 - 0.0094 15.2 3.7 2.4 7.3 0.1 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OEU15273.1 - 0.012 15.7 0.2 0.26 11.3 0.0 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AATF-Che1 PF13339.6 OEU15273.1 - 0.62 10.8 2.9 0.82 10.4 0.7 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor TPR_MLP1_2 PF07926.12 OEU15273.1 - 0.82 9.7 5.5 2.7 8.1 0.2 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Clathrin PF00637.20 OEU15273.1 - 1.4 8.8 4.9 4.4 7.2 0.6 2.9 1 1 2 3 3 3 0 Region in Clathrin and VPS CCDC53 PF10152.9 OEU15274.1 - 1.1e-07 32.4 0.0 1.1e-07 32.4 0.0 5.2 3 2 0 3 3 3 1 Subunit CCDC53 of WASH complex DUF641 PF04859.12 OEU15274.1 - 0.02 15.2 9.4 0.86 9.9 2.8 4.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.10 OEU15274.1 - 0.035 14.5 0.3 0.11 12.9 0.3 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cep57_MT_bd PF06657.13 OEU15274.1 - 0.23 11.9 3.6 0.96 9.9 2.6 2.7 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CC2-LZ PF16516.5 OEU15274.1 - 1.9 8.9 12.2 2 8.9 1.6 3.5 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fe-S_biosyn PF01521.20 OEU15275.1 - 2.2e-18 66.4 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DP PF08781.10 OEU15276.1 - 5.1e-30 104.2 3.2 7.7e-30 103.6 2.0 1.9 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.20 OEU15276.1 - 5.5e-21 74.4 0.8 1.2e-20 73.3 0.8 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DHO_dh PF01180.21 OEU15277.1 - 2.4e-57 194.4 0.1 2.7e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 OEU15277.1 - 0.00082 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OEU15277.1 - 0.0069 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OEU15277.1 - 0.015 14.3 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OEU15277.1 - 0.03 13.7 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 OEU15277.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FlpD PF02662.16 OEU15277.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit UPF0016 PF01169.19 OEU15279.1 - 1.2e-43 147.3 16.7 5.8e-23 81.0 2.8 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 OEU15279.1 - 2.5e-05 24.1 3.3 3.1e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Integral membrane protein TerC family OFeT_1 PF16955.5 OEU15279.1 - 0.00014 21.6 0.1 0.0002 21.1 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter Cad PF03596.13 OEU15279.1 - 0.031 14.2 1.7 0.034 14.0 0.1 1.7 2 0 0 2 2 2 0 Cadmium resistance transporter UQ_con PF00179.26 OEU15280.1 - 1.9e-38 131.3 0.0 2.2e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADIP PF11559.8 OEU15280.1 - 6.7e-05 23.0 0.0 7.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding RWD PF05773.22 OEU15280.1 - 0.016 15.5 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain DUF1154 PF06631.11 OEU15280.1 - 3.8 7.6 9.9 1.4 9.0 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) NifU PF01106.17 OEU15281.1 - 0.01 15.9 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 0 NifU-like domain 14-3-3 PF00244.20 OEU15282.1 - 2e-103 344.7 1.4 2.3e-103 344.5 1.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 OEU15282.1 - 0.15 12.1 1.0 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FlaF DrrA_P4M PF14860.6 OEU15282.1 - 0.32 10.8 3.0 0.46 10.4 0.3 2.5 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF4743 PF15916.5 OEU15283.1 - 1.9e-15 56.9 0.0 3.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OEU15283.1 - 1.3e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ant_C PF05586.11 OEU15285.1 - 0.13 12.9 6.9 5.9 7.6 0.0 2.9 2 0 0 2 2 2 0 Anthrax receptor C-terminus region DDHD PF02862.17 OEU15285.1 - 2.1 8.4 10.3 0.6 10.2 5.2 2.2 2 0 0 2 2 2 0 DDHD domain Presenilin PF01080.17 OEU15285.1 - 6.5 5.4 12.1 0.49 9.1 7.4 1.5 2 0 0 2 2 2 0 Presenilin Atrophin-1 PF03154.15 OEU15285.1 - 8.8 4.5 11.1 13 3.9 11.1 1.3 1 0 0 1 1 1 0 Atrophin-1 family DUF2057 PF09829.9 OEU15288.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Proteasome PF00227.26 OEU15289.1 - 5.4e-21 74.9 0.0 6.6e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU15289.1 - 6.1e-09 35.4 0.1 9e-09 34.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SNF2_N PF00176.23 OEU15290.1 - 9.4e-49 166.0 0.0 1.7e-47 161.9 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU15290.1 - 1.3e-18 67.3 0.0 2e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15290.1 - 3.8e-09 36.8 0.0 9.2e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU15290.1 - 0.011 14.9 0.0 0.038 13.1 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OEU15290.1 - 0.12 11.6 0.7 0.37 9.9 0.2 2.0 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF3736 PF12540.8 OEU15291.1 - 0.15 12.2 0.1 0.41 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) Thymidylat_synt PF00303.19 OEU15292.1 - 2e-05 23.9 0.0 2.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase PGPGW PF09656.10 OEU15293.1 - 1.1e-09 37.6 1.9 2.1e-09 36.8 1.9 1.4 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) NIF PF03031.18 OEU15294.1 - 3.5e-54 182.8 0.2 4.3e-54 182.5 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HTH_Tnp_IS1 PF12759.7 OEU15294.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 InsA C-terminal domain HAD PF12710.7 OEU15294.1 - 0.036 14.5 0.1 0.52 10.7 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Sec23_trunk PF04811.15 OEU15295.1 - 1.2e-56 192.0 0.0 3.7e-43 147.8 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OEU15295.1 - 7.5e-26 90.7 0.0 1.6e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OEU15295.1 - 2.1e-21 75.7 0.2 5.5e-21 74.3 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OEU15295.1 - 2e-17 63.0 6.8 4e-17 62.0 6.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OEU15295.1 - 4.4e-11 42.5 0.0 9.7e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 OEU15295.1 - 0.04 14.6 0.0 2.2 9.0 0.0 3.0 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF3015 PF11220.8 OEU15296.1 - 0.088 12.7 0.7 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) DUF885 PF05960.11 OEU15297.1 - 0.00019 21.2 1.7 0.00019 21.2 1.7 2.4 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF885) DUF1192 PF06698.11 OEU15297.1 - 0.049 13.7 0.1 0.049 13.7 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Collagen_mid PF15984.5 OEU15297.1 - 0.051 13.3 0.5 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF3316 PF11777.8 OEU15297.1 - 0.062 13.4 4.6 0.15 12.1 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) YvfG PF09628.10 OEU15297.1 - 0.44 10.9 2.7 1.5 9.2 0.2 3.0 3 0 0 3 3 3 0 YvfG protein Baculo_PEP_C PF04513.12 OEU15297.1 - 0.93 9.5 17.4 0.053 13.6 4.5 3.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_MT_bd PF06657.13 OEU15297.1 - 1.8 9.1 23.2 0.19 12.2 1.1 4.8 3 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 zf-RanBP PF00641.18 OEU15298.1 - 0.0015 17.8 12.9 0.024 14.0 5.8 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Ribosomal_L37ae PF01780.19 OEU15298.1 - 1.5 9.0 4.7 2.9 8.1 0.2 2.6 2 0 0 2 2 2 0 Ribosomal L37ae protein family Pkinase PF00069.25 OEU15300.1 - 2.2e-77 260.0 0.2 2.6e-77 259.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15300.1 - 1.3e-35 122.9 0.0 1.7e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU15300.1 - 5.1e-06 26.0 0.2 8.6e-06 25.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU15300.1 - 5.7e-05 22.1 0.1 0.00014 20.7 0.0 1.8 2 1 0 2 2 2 1 Fungal protein kinase PACT_coil_coil PF10495.9 OEU15300.1 - 0.067 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein HAUS-augmin3 PF14932.6 OEU15301.1 - 0.0092 15.6 14.8 0.0092 15.6 14.8 5.1 2 2 2 5 5 5 2 HAUS augmin-like complex subunit 3 zf-Di19 PF05605.12 OEU15301.1 - 0.077 13.3 0.9 0.2 12.0 0.9 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LEA_4 PF02987.16 OEU15301.1 - 3.8 7.7 20.2 12 6.0 20.2 1.9 1 0 0 1 1 1 0 Late embryogenesis abundant protein Sec20 PF03908.13 OEU15301.1 - 4.9 7.1 16.5 8 6.5 5.0 3.5 1 1 2 3 3 3 0 Sec20 GFD1 PF17331.2 OEU15302.1 - 0.46 10.7 9.4 0.074 13.3 4.2 2.6 2 0 0 2 2 2 0 GFD1 mRNA transport factor IMUP PF15761.5 OEU15304.1 - 0.05 14.3 2.4 0.05 14.3 2.4 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 OEU15304.1 - 1 8.9 7.7 0.12 12.0 3.6 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_A_exo1 PF01612.20 OEU15305.1 - 0.013 15.3 0.3 0.089 12.5 0.3 1.9 1 1 0 1 1 1 0 3'-5' exonuclease HET-S PF17108.5 OEU15305.1 - 0.49 10.2 2.1 21 5.0 0.4 2.3 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic T2SSS_2 PF16549.5 OEU15306.1 - 0.0057 16.6 0.2 0.017 15.1 0.1 1.9 1 1 0 1 1 1 1 Type II secretion system (T2SS) pilotin, S protein T2SS_PulS_OutS PF09691.10 OEU15306.1 - 0.019 15.2 0.1 0.056 13.6 0.1 1.9 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) Herpes_capsid PF06112.11 OEU15306.1 - 0.041 14.0 10.5 0.089 12.9 10.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein EF-hand_like PF09279.11 OEU15306.1 - 0.24 11.9 2.2 0.87 10.1 2.2 1.9 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like MCD_N PF17408.2 OEU15306.1 - 1.2 9.3 6.9 12 6.1 0.1 4.3 2 1 3 5 5 5 0 Malonyl-CoA decarboxylase N-terminal domain HTH_Tnp_4 PF13613.6 OEU15307.1 - 0.24 11.2 0.4 8.2 6.2 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease PI3K_1B_p101 PF10486.9 OEU15307.1 - 1.4 6.6 5.1 1.7 6.4 5.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Beta_propel PF09826.9 OEU15308.1 - 2.3e-85 287.4 5.2 3.7e-85 286.7 5.2 1.3 1 0 0 1 1 1 1 Beta propeller domain Silic_transp PF03842.13 OEU15309.1 - 1.1e-176 588.2 8.4 1.2e-176 588.0 8.4 1.0 1 0 0 1 1 1 1 Silicon transporter DUF21 PF01595.20 OEU15309.1 - 0.0018 18.0 1.6 0.0018 18.0 1.6 2.5 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain CBFD_NFYB_HMF PF00808.23 OEU15310.1 - 1.1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU15310.1 - 4.1e-07 30.4 0.1 5.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OEU15310.1 - 0.011 15.8 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold B12-binding PF02310.19 OEU15310.1 - 0.055 13.5 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain Bromo_TP PF07524.13 OEU15310.1 - 0.062 13.3 0.1 0.23 11.5 0.1 1.9 1 1 1 2 2 2 0 Bromodomain associated TAF PF02969.17 OEU15310.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) F-box PF00646.33 OEU15312.1 - 0.0032 17.3 0.2 0.011 15.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain PNKP-ligase_C PF16536.5 OEU15312.1 - 0.097 12.9 0.1 0.91 9.8 0.0 2.5 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Med3 PF11593.8 OEU15312.1 - 3.8 6.6 8.7 5.7 6.0 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CcmD PF04995.14 OEU15312.1 - 9.1 6.5 7.5 20 5.3 7.5 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) HI0933_like PF03486.14 OEU15314.1 - 1.7e-96 323.4 0.0 2.2e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OEU15314.1 - 2.7e-08 33.4 0.3 0.011 15.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU15314.1 - 1.4e-06 28.2 4.5 0.039 13.5 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU15314.1 - 0.00022 20.4 8.1 0.002 17.3 5.3 2.6 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OEU15314.1 - 0.0043 17.6 4.5 0.92 10.1 1.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU15314.1 - 0.0048 16.0 5.8 0.37 9.8 3.0 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OEU15314.1 - 0.0058 16.6 0.3 0.056 13.4 0.3 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OEU15314.1 - 0.01 15.1 1.2 0.21 10.8 0.1 3.0 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU15314.1 - 0.02 15.1 0.9 0.058 13.6 0.9 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OEU15314.1 - 0.032 13.6 5.7 0.053 12.9 5.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OEU15314.1 - 0.035 13.4 0.3 0.2 10.9 0.6 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OEU15314.1 - 0.056 12.7 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase LBR_tudor PF09465.10 OEU15314.1 - 0.059 13.2 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain FAD_binding_3 PF01494.19 OEU15314.1 - 0.12 11.5 1.5 2.5 7.3 1.1 2.8 2 1 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 OEU15314.1 - 0.39 9.5 2.7 0.76 8.6 2.7 1.4 1 0 0 1 1 1 0 Tryptophan halogenase V_ATPase_I PF01496.19 OEU15315.1 - 8.8e-07 27.3 2.5 8.8e-07 27.3 2.5 1.3 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family CSG2 PF16965.5 OEU15315.1 - 0.0034 16.4 3.2 0.005 15.8 3.2 1.2 1 0 0 1 1 1 1 Ceramide synthase regulator SARAF PF06682.12 OEU15315.1 - 0.011 15.5 4.2 0.016 14.9 4.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Synaptobrevin PF00957.21 OEU15315.1 - 0.015 15.1 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 0 Synaptobrevin CLN3 PF02487.17 OEU15315.1 - 0.028 13.5 0.7 0.047 12.7 0.7 1.4 1 0 0 1 1 1 0 CLN3 protein Peroxin-13_N PF04088.13 OEU15315.1 - 0.099 12.9 6.6 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Peroxin 13, N-terminal region SID-1_RNA_chan PF13965.6 OEU15315.1 - 0.19 10.1 2.5 0.24 9.8 2.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TRAP_alpha PF03896.16 OEU15315.1 - 0.33 10.1 6.9 0.024 13.9 0.9 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit OATP PF03137.20 OEU15315.1 - 0.34 9.1 2.1 0.58 8.4 1.8 1.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.16 OEU15315.1 - 1.1 9.3 3.4 1.8 8.6 3.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CHD5 PF04420.14 OEU15315.1 - 1.2 9.0 5.2 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 CHD5-like protein CrgA PF06781.12 OEU15315.1 - 3 8.0 0.0 3 8.0 0.0 2.8 3 1 0 3 3 3 0 Cell division protein CrgA Orf78 PF06024.12 OEU15315.1 - 3.7 7.9 0.0 3.7 7.9 0.0 3.1 3 1 0 3 3 2 0 Orf78 (ac78) Ctr PF04145.15 OEU15315.1 - 8.8 6.9 7.4 1.2 9.7 3.0 1.9 2 1 0 2 2 2 0 Ctr copper transporter family adh_short PF00106.25 OEU15316.1 - 2.9e-31 108.4 0.0 3.6e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU15316.1 - 1.5e-17 63.9 0.0 2.1e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU15316.1 - 7.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU15316.1 - 0.00082 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 OEU15316.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_33 PF10017.9 OEU15316.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Chloroa_b-bind PF00504.21 OEU15317.1 - 1.7e-40 139.2 0.0 2.7e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein UPF0225 PF17775.1 OEU15318.1 - 9e-18 64.9 0.4 1.3e-17 64.4 0.4 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 OEU15318.1 - 0.0056 16.6 4.6 0.011 15.6 4.6 1.5 1 0 0 1 1 1 1 SEC-C motif SLATT_5 PF18160.1 OEU15318.1 - 0.19 11.0 0.5 0.26 10.6 0.5 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DJ-1_PfpI PF01965.24 OEU15320.1 - 3.9e-19 69.0 0.0 1.7e-18 67.0 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OEU15320.1 - 1.5e-12 47.6 0.0 3e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 OEU15320.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CTP_transf_like PF01467.26 OEU15321.1 - 2.9e-09 37.2 0.0 4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Rsm22 PF09243.10 OEU15322.1 - 3.1e-20 72.6 0.1 2.5e-14 53.2 0.0 3.8 3 1 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 DUF150 PF02576.17 OEU15322.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RimP N-terminal domain CAP PF00188.26 OEU15323.1 - 0.0068 17.3 0.1 0.056 14.3 0.0 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family bZIP_1 PF00170.21 OEU15324.1 - 8e-09 35.5 4.9 8e-09 35.5 4.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OEU15324.1 - 8.3e-06 25.8 5.9 8.3e-06 25.8 5.9 2.8 2 1 1 3 3 3 1 Basic region leucine zipper SUIM_assoc PF16619.5 OEU15324.1 - 4.7 7.3 25.9 3.9 7.6 18.6 4.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SAC3_GANP PF03399.16 OEU15325.1 - 6.1e-18 65.2 0.3 6.6e-16 58.5 0.1 2.2 2 0 0 2 2 2 2 SAC3/GANP family RuBisCo_chap_C PF18087.1 OEU15326.1 - 9.1e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Rubisco Assembly chaperone C-terminal domain HhH-GPD PF00730.25 OEU15327.1 - 5.3e-19 68.7 0.0 8.7e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OEU15327.1 - 3.5e-06 26.6 0.1 8.5e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_8 PF14716.6 OEU15327.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Methyltransf_28 PF02636.17 OEU15329.1 - 2.4e-24 86.4 0.0 3.9e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 OEU15329.1 - 0.03 15.0 3.4 0.075 13.8 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain DUF2099 PF09872.9 OEU15329.1 - 0.087 12.0 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) ATP11 PF06644.11 OEU15331.1 - 5.3e-20 72.3 0.0 9.1e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 ATP11 protein CTD_bind PF04818.13 OEU15332.1 - 1.6e-05 25.6 1.2 4.9e-05 24.1 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. NAC PF01849.18 OEU15333.1 - 6.4e-22 77.3 0.0 1.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.19 OEU15333.1 - 0.035 14.7 0.7 0.035 14.7 0.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LBR_tudor PF09465.10 OEU15334.1 - 3.7e-07 29.8 1.8 7.8e-07 28.8 1.8 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 OEU15334.1 - 0.00028 20.5 0.3 0.00064 19.3 0.3 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 OEU15334.1 - 0.0017 18.2 0.1 0.0068 16.2 0.1 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain SNF2_N PF00176.23 OEU15335.1 - 2.7e-45 154.6 0.1 8.6e-45 153.0 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU15335.1 - 3.3e-20 72.5 0.4 5.8e-19 68.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15335.1 - 7.4e-10 39.1 1.6 4.7e-09 36.5 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU15335.1 - 1.9e-07 30.6 0.0 4.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU15335.1 - 2.6e-07 30.6 0.1 6.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Hydrolase_6 PF13344.6 OEU15335.1 - 0.0022 18.0 0.0 1.2 9.2 0.0 3.0 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase ERCC3_RAD25_C PF16203.5 OEU15335.1 - 0.0082 15.4 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CBS PF00571.28 OEU15336.1 - 3.9e-20 72.0 0.2 1.3e-11 44.8 0.1 2.5 3 0 0 3 3 3 2 CBS domain FIT1_2 PF17357.2 OEU15336.1 - 0.11 12.6 0.8 9.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 KH_1 PF00013.29 OEU15337.1 - 1.2e-10 41.0 2.6 2.6e-10 40.0 2.6 1.6 1 1 0 1 1 1 1 KH domain FAA_hydro_N_2 PF18288.1 OEU15337.1 - 0.043 14.2 0.7 0.066 13.6 0.7 1.4 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 TIM PF00121.18 OEU15338.1 - 6.1e-80 268.1 0.2 1.2e-79 267.2 0.0 1.5 2 0 0 2 2 2 1 Triosephosphate isomerase Gp_dh_C PF02800.20 OEU15338.1 - 2.3e-66 222.2 0.0 4e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU15338.1 - 1.3e-34 118.5 0.4 3.8e-34 117.1 0.2 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OEU15338.1 - 0.022 14.9 0.4 0.072 13.2 0.4 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 OEU15338.1 - 0.067 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OEU15338.1 - 0.099 12.6 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.20 OEU15339.1 - 2.9e-67 225.2 0.0 6.6e-67 224.0 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OEU15339.1 - 2.1e-35 121.1 0.1 3.8e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OEU15339.1 - 0.0055 16.8 0.2 0.011 15.9 0.2 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 OEU15339.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bromodomain PF00439.25 OEU15340.1 - 2.3e-16 59.6 0.0 5.9e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 OEU15340.1 - 0.00015 21.6 16.6 0.00015 21.6 16.6 3.3 3 0 0 3 3 3 1 PHD-finger SNF5 PF04855.12 OEU15340.1 - 0.059 13.2 0.0 0.059 13.2 0.0 2.6 4 0 0 4 4 4 0 SNF5 / SMARCB1 / INI1 PCB_OB PF17092.5 OEU15340.1 - 0.1 13.4 0.1 0.71 10.6 0.0 2.5 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain zf-4CXXC_R1 PF10497.9 OEU15340.1 - 0.32 11.2 27.5 0.025 14.8 13.5 3.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Med7 PF05983.11 OEU15342.1 - 1.7e-14 54.3 12.7 3e-13 50.3 12.7 2.1 1 1 0 1 1 1 1 MED7 protein FAM150 PF15129.6 OEU15342.1 - 0.0011 19.1 0.5 0.0017 18.5 0.5 1.3 1 0 0 1 1 1 1 FAM150 family PhyH PF05721.13 OEU15343.1 - 8.3e-09 36.0 0.2 1.7e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF585 PF04522.12 OEU15343.1 - 0.022 14.4 0.2 0.05 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF585) DEAD PF00270.29 OEU15344.1 - 2e-41 141.7 0.0 5e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU15344.1 - 1.2e-27 96.5 0.1 6.8e-27 94.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15344.1 - 4e-05 23.7 0.0 8.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 OEU15344.1 - 0.0019 17.8 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU15344.1 - 0.019 15.3 0.1 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3245 PF11595.8 OEU15344.1 - 0.023 15.2 0.5 0.059 13.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) AAA_22 PF13401.6 OEU15344.1 - 0.06 13.6 1.6 0.27 11.5 0.5 2.6 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OEU15344.1 - 0.083 12.6 0.1 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OEU15344.1 - 0.12 12.8 0.0 0.43 11.0 0.0 2.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) T4SS-DNA_transf PF02534.14 OEU15344.1 - 0.15 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Methyltr_RsmB-F PF01189.17 OEU15345.1 - 1.8e-31 109.4 0.0 1.3e-29 103.3 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 OEU15345.1 - 5.9e-07 29.4 0.3 1.6e-06 28.0 0.3 1.7 1 1 0 1 1 1 1 PUA domain SNF2_N PF00176.23 OEU15346.1 - 2.1e-33 115.5 0.0 2.9e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU15346.1 - 4.9e-10 39.7 0.2 1.5e-08 34.9 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15346.1 - 2.3e-09 37.5 0.0 8.1e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 OEU15346.1 - 0.0014 18.3 0.1 0.0038 16.9 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 HycH PF07450.11 OEU15346.1 - 0.027 14.8 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH TniB PF05621.11 OEU15346.1 - 0.059 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein ERCC3_RAD25_C PF16203.5 OEU15346.1 - 0.066 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GPS PF01825.21 OEU15347.1 - 0.07 13.7 1.0 0.07 13.7 1.0 3.6 3 0 0 3 3 3 0 GPCR proteolysis site, GPS, motif CDC45 PF02724.14 OEU15348.1 - 0.05 11.9 1.8 0.083 11.2 1.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OEU15348.1 - 2.2 6.4 5.5 3.3 5.8 5.5 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OEU15348.1 - 7.8 5.7 18.8 16 4.7 18.8 1.5 1 0 0 1 1 1 0 NOA36 protein Cyclin_N PF00134.23 OEU15349.1 - 1.6e-15 57.0 0.2 3.2e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain HA PF03457.14 OEU15350.1 - 1.1e-18 67.3 0.1 8.9e-06 25.9 0.0 4.2 4 0 0 4 4 4 4 Helicase associated domain EF-hand_4 PF12763.7 OEU15350.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Acetyltransf_1 PF00583.25 OEU15351.1 - 1.7e-10 41.1 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU15351.1 - 1e-07 32.0 0.0 2.7e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU15351.1 - 1.7e-07 31.6 0.0 3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU15351.1 - 0.00067 19.6 0.0 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 OEU15351.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OEU15351.1 - 0.15 12.7 0.0 0.21 12.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 OEU15353.1 - 8.5e-45 152.6 0.5 1.2e-44 152.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU15353.1 - 2.1e-24 86.4 0.1 2.8e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU15353.1 - 3.2e-11 43.5 0.1 5e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU15353.1 - 0.00056 19.1 0.1 0.00078 18.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OEU15353.1 - 0.0025 17.3 0.2 0.0081 15.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABC_cobalt PF09819.9 OEU15353.1 - 0.043 14.0 0.1 1.5 8.9 0.0 2.7 3 1 0 3 3 3 0 ABC-type cobalt transport system, permease component DUF520 PF04461.13 OEU15353.1 - 0.085 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF520) ApbA PF02558.16 OEU15353.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4179 PF13786.6 OEU15353.1 - 0.4 11.2 2.3 5.1 7.7 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) P_C PF06640.11 OEU15354.1 - 0.04 14.1 0.8 0.04 14.1 0.8 1.6 2 0 0 2 2 2 0 P protein C-terminus Med13_C PF06333.12 OEU15354.1 - 0.14 11.4 2.5 0.075 12.3 0.6 1.5 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain DnaJ PF00226.31 OEU15355.1 - 8.6e-27 93.1 2.3 1.5e-26 92.2 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF5348 PF17295.2 OEU15355.1 - 0.12 12.3 0.1 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5348) Las1 PF04031.13 OEU15356.1 - 3e-36 124.9 0.5 6.4e-36 123.8 0.5 1.6 1 0 0 1 1 1 1 Las1-like L_biotic_typeA PF04604.13 OEU15356.1 - 0.02 14.8 0.2 0.059 13.2 0.2 1.8 1 0 0 1 1 1 0 Type-A lantibiotic Amino_oxidase PF01593.24 OEU15358.1 - 1.6e-69 235.3 0.0 2.1e-69 235.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU15358.1 - 2.9e-13 49.8 0.0 7.6e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU15358.1 - 6.4e-11 42.4 1.2 1.7e-10 41.0 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU15358.1 - 3.5e-06 26.5 0.1 0.012 14.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU15358.1 - 3e-05 23.4 1.4 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU15358.1 - 0.00011 21.6 0.1 0.00018 20.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OEU15358.1 - 0.00013 20.9 3.7 0.22 10.2 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 OEU15358.1 - 0.00021 21.3 0.2 0.11 12.4 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding MCRA PF06100.11 OEU15358.1 - 0.00033 19.6 0.0 0.00048 19.0 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox PF00070.27 OEU15358.1 - 0.00048 20.6 1.1 0.031 14.8 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU15358.1 - 0.00096 18.5 0.3 0.0024 17.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OEU15358.1 - 0.001 18.3 0.1 0.0023 17.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OEU15358.1 - 0.0014 17.7 0.3 0.11 11.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 OEU15358.1 - 0.0036 16.4 3.4 0.024 13.7 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU15358.1 - 0.023 14.0 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase YrhC PF14143.6 OEU15358.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 YrhC-like protein DUF2423 PF10338.9 OEU15359.1 - 9.1e-09 35.4 1.7 9.1e-09 35.4 1.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Complex1_LYR PF05347.15 OEU15359.1 - 0.63 10.1 3.5 0.27 11.3 0.6 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Ku PF02735.16 OEU15360.1 - 2.8e-19 69.6 0.0 8.5e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Iwr1 PF08574.10 OEU15360.1 - 0.0049 17.8 15.3 0.04 14.9 8.4 3.0 2 0 0 2 2 2 1 Transcription factor Iwr1 Ku_N PF03731.15 OEU15360.1 - 0.0079 16.0 2.7 0.02 14.6 0.4 2.6 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Tfb4 PF03850.14 OEU15360.1 - 0.024 14.1 0.0 0.06 12.8 0.1 1.7 2 0 0 2 2 2 0 Transcription factor Tfb4 RXT2_N PF08595.11 OEU15360.1 - 0.11 12.6 6.0 1.3 9.1 2.6 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal FANCI_HD2 PF14680.6 OEU15360.1 - 0.15 11.2 0.3 0.74 9.0 0.3 2.1 2 0 0 2 2 2 0 FANCI helical domain 2 CENP-B_dimeris PF09026.10 OEU15360.1 - 1 9.8 18.2 0.7 10.3 9.2 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OEU15360.1 - 2.4 6.1 8.0 0.33 9.0 1.4 2.1 2 0 0 2 2 2 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OEU15360.1 - 6.5 6.4 15.8 6.1 6.5 7.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OEU15360.1 - 8 5.7 13.8 2.1 7.6 6.2 2.3 2 0 0 2 2 2 0 NOA36 protein DUF2457 PF10446.9 OEU15360.1 - 8.5 5.4 13.6 0.25 10.4 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) AF-4 PF05110.13 OEU15362.1 - 2.2 6.3 6.1 2.6 6.0 6.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ion_trans_2 PF07885.16 OEU15363.1 - 1.5e-28 98.6 20.3 1.2e-15 57.2 3.4 2.2 2 0 0 2 2 2 2 Ion channel EF-hand_5 PF13202.6 OEU15363.1 - 3.8e-08 32.5 0.3 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OEU15363.1 - 2.6e-07 29.7 1.1 0.0019 17.6 0.1 2.4 2 0 0 2 2 2 2 EF hand Ion_trans PF00520.31 OEU15363.1 - 2.4e-06 26.9 4.1 0.015 14.5 0.7 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_6 PF13405.6 OEU15363.1 - 1.1e-05 25.0 1.0 0.19 11.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU15363.1 - 4.3e-05 23.9 0.7 0.12 12.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OEU15363.1 - 0.0019 18.0 0.3 0.031 14.1 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain pair RRM_1 PF00076.22 OEU15364.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OAD_gamma PF04277.13 OEU15365.1 - 0.42 11.2 4.4 0.59 10.8 3.9 1.6 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RPN7 PF10602.9 OEU15366.1 - 3e-34 118.2 0.1 4.4e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OEU15366.1 - 2.3e-12 47.4 0.0 6.3e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain HiaBD2 PF15403.6 OEU15366.1 - 0.03 14.7 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Peptidase_C14 PF00656.22 OEU15368.1 - 2.4e-23 83.4 0.1 7.2e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Caspase domain DUF4898 PF16239.5 OEU15368.1 - 0.15 12.1 0.5 2 8.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4898) START PF01852.19 OEU15369.1 - 1.6e-11 44.0 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 START domain SPT16 PF08644.11 OEU15370.1 - 3.4e-50 170.1 0.1 6.8e-49 165.9 0.0 3.0 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OEU15370.1 - 4.5e-33 114.3 0.0 1.1e-32 113.1 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OEU15370.1 - 1.9e-29 102.9 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OEU15370.1 - 2.7e-13 50.2 0.1 5.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.12 OEU15370.1 - 2.7 6.1 39.1 2.1 6.5 7.1 2.3 2 0 0 2 2 2 0 Nop14-like family RAB3GAP2_N PF14655.6 OEU15371.1 - 7.5e-31 107.8 0.0 1.5e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 OEU15371.1 - 4e-07 28.7 0.2 0.0016 16.8 0.1 3.0 3 0 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit C-terminus TPR_2 PF07719.17 OEU15372.1 - 2e-23 80.6 21.8 0.0035 17.3 0.4 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 OEU15372.1 - 2.3e-19 69.6 11.8 9.2e-05 22.9 0.5 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OEU15372.1 - 4.8e-18 64.3 27.8 0.013 16.3 0.1 10.1 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15372.1 - 2.3e-17 61.7 9.4 0.043 14.0 0.1 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15372.1 - 9.7e-17 60.0 8.7 0.011 15.5 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 OEU15372.1 - 8.5e-16 58.3 22.6 0.0002 22.0 0.6 6.4 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 OEU15372.1 - 3e-14 53.1 18.7 0.048 14.0 1.7 8.0 5 3 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 OEU15372.1 - 1.4e-09 37.6 0.1 0.22 12.0 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU15372.1 - 1.7e-08 34.0 0.5 0.0012 18.5 0.2 5.6 5 1 1 6 6 6 1 TPR repeat TPR_7 PF13176.6 OEU15372.1 - 1.3e-07 31.1 19.2 4 7.7 0.3 10.5 11 1 1 12 12 12 2 Tetratricopeptide repeat MIT PF04212.18 OEU15372.1 - 0.00014 21.9 2.3 2 8.6 0.1 4.9 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain PPR PF01535.20 OEU15372.1 - 0.00043 20.4 1.9 91 3.6 0.1 6.5 7 0 0 7 7 6 0 PPR repeat ANAPC3 PF12895.7 OEU15372.1 - 0.0041 17.3 8.4 3.5 7.9 0.0 5.0 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 OEU15372.1 - 0.0047 16.9 2.9 25 4.9 0.0 5.7 5 2 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_10 PF13374.6 OEU15372.1 - 0.0058 16.5 15.9 1.9 8.5 0.4 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU15372.1 - 0.02 15.0 21.7 0.62 10.3 0.4 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU15372.1 - 0.034 14.8 17.9 34 5.4 0.1 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 OEU15372.1 - 0.88 10.4 11.8 25 5.9 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Macoilin PF09726.9 OEU15373.1 - 1.9 7.0 20.1 2.1 6.8 20.1 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 OEU15373.1 - 3.2 6.3 10.6 3.7 6.1 10.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_M20 PF01546.28 OEU15374.1 - 3e-33 115.3 0.1 3.9e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OEU15374.1 - 2.6e-08 33.8 0.0 8.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain DnaJ PF00226.31 OEU15375.1 - 9.4e-24 83.3 2.0 1.1e-23 83.1 2.0 1.1 1 0 0 1 1 1 1 DnaJ domain FlbT PF07378.11 OEU15375.1 - 0.019 15.0 0.3 0.028 14.5 0.3 1.4 1 1 0 1 1 1 0 Flagellar protein FlbT TPR_2 PF07719.17 OEU15376.1 - 3.3e-08 33.0 0.0 0.0006 19.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15376.1 - 1.1e-07 31.5 0.0 0.00029 20.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU15376.1 - 3.7e-07 30.3 0.0 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15376.1 - 8.8e-07 28.5 0.0 0.00014 21.6 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU15376.1 - 0.00046 20.4 0.0 1.8 9.1 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU15376.1 - 0.00066 20.1 0.0 0.007 16.9 0.0 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU15376.1 - 0.0011 19.6 0.0 0.82 10.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU15376.1 - 0.002 18.7 0.0 3 8.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat HTH_23 PF13384.6 OEU15376.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TPR_20 PF14561.6 OEU15376.1 - 0.036 14.4 0.0 0.29 11.5 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU15376.1 - 0.043 13.7 0.0 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1896 PF08989.10 OEU15376.1 - 0.13 12.3 0.1 1.6 8.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1896) TPR_MalT PF17874.1 OEU15376.1 - 0.19 11.1 0.0 0.47 9.8 0.0 1.7 1 1 0 1 1 1 0 MalT-like TPR region DUF3172 PF11371.8 OEU15378.1 - 1.2e-56 190.3 0.2 1.5e-56 189.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) Nucleo_P87 PF07267.11 OEU15378.1 - 0.12 11.2 4.8 0.19 10.6 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RXT2_N PF08595.11 OEU15378.1 - 0.23 11.5 2.8 0.21 11.6 0.7 2.0 2 1 0 2 2 2 0 RXT2-like, N-terminal SelR PF01641.18 OEU15379.1 - 2e-29 102.1 0.1 6.7e-29 100.4 0.0 1.9 2 1 0 2 2 2 1 SelR domain AdoHcyase PF05221.17 OEU15381.1 - 1e-138 461.6 0.0 1.1e-138 461.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OEU15381.1 - 4.8e-80 267.3 3.5 7.6e-80 266.7 3.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OEU15381.1 - 2.7e-08 33.4 0.2 4.6e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OEU15381.1 - 1e-05 25.2 0.1 1.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 OEU15381.1 - 0.001 18.4 1.2 0.0049 16.2 1.2 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 OEU15381.1 - 0.002 18.2 0.2 0.0053 16.8 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OEU15381.1 - 0.02 15.2 0.4 0.11 12.7 0.4 2.2 1 1 0 1 1 1 0 TrkA-N domain DLH PF01738.18 OEU15382.1 - 2.1e-30 105.9 0.0 2.8e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OEU15382.1 - 0.00059 19.4 0.2 0.037 13.5 0.1 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 OEU15382.1 - 0.0029 17.6 0.2 0.018 15.0 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Phage_antitermQ PF06530.12 OEU15382.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q Peripla_BP_4 PF13407.6 OEU15383.1 - 2.1e-17 63.6 6.8 3.2e-17 63.0 6.8 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 OEU15383.1 - 0.031 14.6 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain SpecificRecomb PF10136.9 OEU15384.1 - 0.047 12.0 0.0 0.05 11.9 0.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase PfkB PF00294.24 OEU15385.1 - 1.6e-21 76.9 0.1 8.8e-12 44.9 0.0 3.0 3 0 0 3 3 3 2 pfkB family carbohydrate kinase RCDG1 PF15725.5 OEU15386.1 - 1.4 9.4 0.1 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein DSHCT PF08148.12 OEU15387.1 - 1.5e-52 177.6 0.1 2.9e-52 176.6 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OEU15387.1 - 4.2e-17 62.5 0.0 8.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 OEU15387.1 - 2.8e-15 57.0 1.2 1.2e-14 54.9 1.2 2.1 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.15 OEU15387.1 - 8.6e-07 29.1 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU15387.1 - 3.1e-06 27.5 0.1 8.9e-05 22.8 0.1 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OEU15387.1 - 0.053 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OEU15387.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein FA_hydroxylase PF04116.13 OEU15388.1 - 2.2e-15 57.2 17.1 2.2e-15 57.2 17.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short_C2 PF13561.6 OEU15389.1 - 2.7e-50 171.1 0.4 3.4e-50 170.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU15389.1 - 5.7e-42 143.4 2.2 7.4e-42 143.0 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU15389.1 - 2.8e-05 24.1 0.4 0.0001 22.3 0.3 1.8 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 OEU15389.1 - 0.00018 20.9 0.5 0.00054 19.3 0.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HSF_DNA-bind PF00447.17 OEU15390.1 - 1.9e-24 86.1 0.4 5.3e-24 84.7 0.4 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Trs65 PF12735.7 OEU15391.1 - 1.7e-07 31.0 0.2 7.8e-07 28.8 0.2 2.1 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 CENP-B_dimeris PF09026.10 OEU15391.1 - 0.086 13.2 2.9 0.14 12.5 2.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Symplekin_C PF12295.8 OEU15393.1 - 2.7e-24 86.3 0.0 3e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal His_Phos_2 PF00328.22 OEU15394.1 - 1.3e-15 57.6 0.1 4.6e-15 55.9 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NifU PF01106.17 OEU15395.1 - 1.9e-22 79.2 0.3 2e-22 79.1 0.3 1.0 1 0 0 1 1 1 1 NifU-like domain DUF211 PF02680.14 OEU15395.1 - 0.058 13.6 0.1 0.073 13.2 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF2012 PF09430.10 OEU15396.1 - 5.4e-23 81.4 0.0 8.3e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 OEU15396.1 - 0.0069 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OEU15396.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain SOP4 PF17081.5 OEU15396.1 - 0.046 13.2 0.5 0.088 12.3 0.2 1.5 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein Chloroa_b-bind PF00504.21 OEU15397.1 - 1.5e-26 93.9 0.2 2.4e-26 93.2 0.2 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EspB PF05802.11 OEU15397.1 - 0.12 12.4 1.8 0.36 10.8 1.8 1.7 1 1 0 1 1 1 0 Enterobacterial EspB protein Pkinase PF00069.25 OEU15398.1 - 2.7e-66 223.7 0.0 3e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15398.1 - 4.5e-28 98.2 0.0 5.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU15398.1 - 3.9e-05 23.1 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OEU15398.1 - 6.7e-05 22.0 0.0 0.00013 21.0 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OEU15398.1 - 0.01 15.8 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Proteasome PF00227.26 OEU15399.1 - 2.8e-16 59.6 0.0 3.4e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU15399.1 - 8.3e-05 22.2 0.2 0.0006 19.4 0.0 2.5 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DUF4748 PF15932.5 OEU15400.1 - 0.27 11.0 3.7 0.61 9.9 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4748) Methyltransf_32 PF13679.6 OEU15401.1 - 3.3e-06 27.2 2.9 4.1e-06 26.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain C_Hendra PF16821.5 OEU15401.1 - 0.05 13.5 4.7 0.093 12.6 4.7 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses Med12-LCEWAV PF12145.8 OEU15401.1 - 0.064 12.1 4.6 0.089 11.6 4.6 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Methyltransf_25 PF13649.6 OEU15401.1 - 0.086 13.6 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 OEU15402.1 - 4.2e-35 121.4 0.0 6e-35 120.9 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15402.1 - 5.5e-15 55.4 0.0 1.4e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU15402.1 - 6.9e-06 26.2 0.2 1.8e-05 24.8 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU15402.1 - 4.2e-05 22.5 0.0 5.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OEU15402.1 - 0.00024 20.8 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OEU15402.1 - 0.00032 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU15402.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Peripla_BP_4 PF13407.6 OEU15403.1 - 1.1e-40 139.8 11.0 6.1e-21 75.1 2.9 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 OEU15403.1 - 7.6e-07 28.8 0.1 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding proteins and sugar binding domain of LacI family ApbA PF02558.16 OEU15403.1 - 0.083 12.5 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.6 OEU15403.1 - 0.14 12.6 0.1 7.1 7.2 0.0 2.7 3 0 0 3 3 3 0 CoA binding domain CoA_binding PF02629.19 OEU15403.1 - 3.8 8.3 5.5 6.7 7.5 0.3 3.0 3 0 0 3 3 3 0 CoA binding domain Nicastrin PF05450.15 OEU15404.1 - 1e-16 61.2 0.0 4.6e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 OEU15404.1 - 5.1e-11 42.9 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 OEU15404.1 - 0.00097 18.9 0.3 0.0021 17.8 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 DUF4432 PF14486.6 OEU15404.1 - 0.057 12.2 0.1 0.095 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) DEAD PF00270.29 OEU15406.1 - 6.9e-32 110.6 0.0 9.3e-31 106.9 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU15406.1 - 3.3e-26 91.8 0.0 6.8e-25 87.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15406.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OEU15406.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps53_N PF04100.12 OEU15407.1 - 8.2e-54 183.0 8.6 2.3e-34 119.0 5.6 3.2 2 1 0 2 2 2 2 Vps53-like, N-terminal COG7 PF10191.9 OEU15407.1 - 0.00011 20.7 6.1 0.0037 15.6 0.0 3.1 3 0 0 3 3 3 1 Golgi complex component 7 (COG7) Spc7 PF08317.11 OEU15407.1 - 0.003 16.5 6.0 0.0063 15.4 6.0 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 OEU15407.1 - 0.003 17.7 4.6 0.003 17.7 4.6 1.8 2 0 0 2 2 1 1 Tropomyosin like DUF2451 PF10474.9 OEU15407.1 - 0.0067 16.2 0.7 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Filament PF00038.21 OEU15407.1 - 0.014 15.0 4.5 0.045 13.3 4.5 1.8 1 0 0 1 1 1 0 Intermediate filament protein DUF4763 PF15960.5 OEU15407.1 - 0.031 13.6 4.3 0.082 12.2 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CCDC32 PF14989.6 OEU15407.1 - 0.035 14.1 2.2 0.091 12.8 2.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Exonuc_VII_L PF02601.15 OEU15407.1 - 0.065 12.8 6.6 0.14 11.7 6.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 OEU15407.1 - 0.12 10.9 3.3 0.18 10.3 3.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 OEU15407.1 - 0.18 12.0 5.7 1.3 9.2 4.8 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 OEU15407.1 - 0.21 11.8 9.6 0.083 13.2 2.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FadA PF09403.10 OEU15407.1 - 0.22 12.0 4.3 0.5 10.9 2.9 2.4 2 0 0 2 2 2 0 Adhesion protein FadA COG2 PF06148.11 OEU15407.1 - 0.27 11.3 5.8 3.1 7.9 5.9 2.8 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 OEU15407.1 - 0.32 11.0 9.1 0.26 11.3 4.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CREPT PF16566.5 OEU15407.1 - 0.4 10.8 11.7 0.16 12.2 5.0 3.0 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour TMPIT PF07851.13 OEU15407.1 - 0.44 9.7 4.5 1.2 8.3 4.5 1.6 1 0 0 1 1 1 0 TMPIT-like protein OrfB_IS605 PF01385.19 OEU15407.1 - 0.69 10.2 4.9 1.7 8.8 4.1 2.1 1 1 0 1 1 1 0 Probable transposase DUF1690 PF07956.11 OEU15407.1 - 0.69 10.3 7.8 0.81 10.1 5.8 2.2 2 0 0 2 2 1 0 Protein of Unknown function (DUF1690) SKA2 PF16740.5 OEU15407.1 - 0.86 9.4 6.8 1.1 9.1 3.0 2.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 OEU15407.1 - 1.2 9.7 6.5 0.61 10.6 2.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region KASH_CCD PF14662.6 OEU15407.1 - 1.5 8.6 10.5 0.08 12.8 4.3 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH BRE1 PF08647.11 OEU15407.1 - 2 8.5 14.9 0.033 14.2 6.1 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DEAD PF00270.29 OEU15409.1 - 3.9e-37 127.7 0.1 6.2e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU15409.1 - 8.6e-25 87.2 0.0 5.9e-24 84.5 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15409.1 - 2.2e-05 24.5 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OEU15409.1 - 0.021 13.6 0.0 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TLP-20 PF06088.11 OEU15409.1 - 0.022 14.6 0.2 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TPR_14 PF13428.6 OEU15410.1 - 2e-10 40.6 12.0 0.14 13.0 0.2 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU15410.1 - 1.6e-07 31.5 3.6 0.28 11.5 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OEU15410.1 - 4.9e-07 30.2 0.4 0.54 10.8 0.0 5.3 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU15410.1 - 1.6e-06 27.8 2.8 0.035 14.2 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU15410.1 - 4.1e-05 24.1 11.2 0.14 12.9 0.3 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15410.1 - 0.00053 20.0 1.4 0.65 10.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU15410.1 - 0.011 16.3 0.1 30 5.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU15410.1 - 0.013 15.5 0.3 0.77 9.9 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU15410.1 - 0.18 11.7 1.2 2.2 8.3 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4407 PF14362.6 OEU15410.1 - 0.45 9.8 3.1 0.74 9.1 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APOC4 PF15119.6 OEU15411.1 - 0.087 13.1 0.3 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein C4 Inhibitor_I53 PF11714.8 OEU15412.1 - 0.023 14.9 2.3 0.064 13.5 2.3 1.7 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Cwf_Cwc_15 PF04889.12 OEU15412.1 - 6.5 6.4 24.9 0.87 9.3 9.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cofilin_ADF PF00241.20 OEU15413.1 - 0.00043 20.1 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SLBP_RNA_bind PF15247.6 OEU15414.1 - 4.2e-17 62.0 0.6 7.7e-17 61.2 0.6 1.4 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain SOBP PF15279.6 OEU15414.1 - 0.94 10.0 9.1 1.1 9.8 9.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_L7Ae PF01248.26 OEU15415.1 - 1.7e-26 91.8 0.1 2.3e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OEU15415.1 - 0.00023 21.0 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Pico_P2B PF01552.17 OEU15415.1 - 0.054 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Picornavirus 2B protein RNase_P_pop3 PF08228.11 OEU15415.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 RNase P subunit Pop3 DFP PF04127.15 OEU15417.1 - 3e-17 63.0 0.0 2.2e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein HHH PF00633.23 OEU15418.1 - 7e-06 25.7 0.9 2.3e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OEU15418.1 - 0.022 15.4 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_8 PF14716.6 OEU15418.1 - 0.07 13.5 0.2 0.2 12.0 0.1 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF92 PF01940.16 OEU15419.1 - 6.4e-53 179.6 10.3 1.1e-52 178.8 10.3 1.4 1 0 0 1 1 1 1 Integral membrane protein DUF92 Mito_carr PF00153.27 OEU15420.1 - 6.4e-32 109.4 1.6 1.3e-17 63.5 0.0 4.2 2 1 1 3 3 3 3 Mitochondrial carrier protein NigD_N PF12667.7 OEU15421.1 - 0.084 13.0 0.0 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 NigD-like N-terminal OB domain BTV_NS2 PF04514.12 OEU15421.1 - 0.12 11.2 0.1 0.12 11.2 0.1 1.5 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Thioredoxin_8 PF13905.6 OEU15422.1 - 2.4e-24 85.5 0.0 3.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OEU15422.1 - 5.1e-09 36.1 0.0 4.6e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OEU15422.1 - 1.5e-06 28.6 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU15422.1 - 7.9e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU15422.1 - 0.00077 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin NADH_4Fe-4S PF10589.9 OEU15422.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_7 PF13899.6 OEU15422.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 OEU15422.1 - 0.17 11.6 0.1 2.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin RNase_P_p30 PF01876.16 OEU15424.1 - 1.4e-27 96.5 0.2 3.5e-26 92.0 0.4 2.1 1 1 1 2 2 2 2 RNase P subunit p30 DTHCT PF08070.11 OEU15424.1 - 0.044 14.5 5.9 2.4 9.0 0.5 3.1 3 0 0 3 3 3 0 DTHCT (NUC029) region Aminotran_1_2 PF00155.21 OEU15425.1 - 1.6e-43 149.3 0.0 1.8e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OEU15425.1 - 0.065 12.5 0.0 0.66 9.2 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Metallophos PF00149.28 OEU15426.1 - 1.7e-34 120.1 0.4 3e-34 119.3 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OEU15426.1 - 0.00065 20.1 0.2 0.0015 18.9 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PseudoU_synth_2 PF00849.22 OEU15427.1 - 9.2e-15 55.1 0.1 3.1e-14 53.4 0.1 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_L4 PF00573.22 OEU15428.1 - 4.4e-36 124.4 0.0 4.4e-36 124.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OEU15428.1 - 1.1e-16 60.6 2.5 1.1e-16 60.6 2.5 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain BBIP10 PF14777.6 OEU15428.1 - 0.15 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 UreF PF01730.16 OEU15428.1 - 0.74 10.4 6.7 6.6 7.3 1.4 2.4 2 0 0 2 2 2 0 UreF DDE_Tnp_1_7 PF13843.6 OEU15430.1 - 1.1e-06 28.2 0.0 7.9e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 Transposase IS4 Adeno_E3_CR2 PF02439.15 OEU15430.1 - 0.058 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SDA1 PF05285.12 OEU15430.1 - 0.44 9.9 13.7 0.53 9.7 13.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OEU15430.1 - 0.67 8.1 15.1 0.82 7.8 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 OEU15430.1 - 1.5 7.7 10.9 1.8 7.4 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CxxCxxCC PF03692.15 OEU15431.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain 2OG-FeII_Oxy_5 PF13759.6 OEU15431.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Kelch_6 PF13964.6 OEU15432.1 - 6.3e-05 23.1 0.9 1.4 9.3 0.0 4.7 4 1 0 4 4 4 2 Kelch motif DUF987 PF06174.11 OEU15432.1 - 0.075 13.0 0.1 20 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF987) DUF4873 PF16170.5 OEU15432.1 - 0.17 12.1 0.7 3.7 7.8 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4873) Helicase_C PF00271.31 OEU15434.1 - 4.4e-16 59.2 0.0 5.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF5018 PF16410.5 OEU15434.1 - 0.034 12.9 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) DUF4834 PF16118.5 OEU15435.1 - 0.0015 19.4 0.1 0.0037 18.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) IQCJ-SCHIP1 PF15157.6 OEU15435.1 - 0.023 14.5 0.7 0.043 13.6 0.7 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF5521 PF17659.1 OEU15435.1 - 0.059 11.2 2.8 0.078 10.8 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) SR-25 PF10500.9 OEU15435.1 - 4.8 6.7 12.0 7.9 6.0 12.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MPP6 PF10175.9 OEU15436.1 - 1.3e-14 54.9 15.8 7.3e-14 52.4 15.8 2.0 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Hamartin PF04388.12 OEU15436.1 - 0.12 11.0 4.3 0.12 11.0 4.3 1.1 1 0 0 1 1 1 0 Hamartin protein DNA_pol_phi PF04931.13 OEU15436.1 - 3.4 5.7 13.0 4.9 5.1 13.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C1 PF00112.23 OEU15437.1 - 1.1e-66 225.1 0.0 1.6e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OEU15437.1 - 5.3e-15 55.6 2.4 9e-15 54.9 2.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OEU15437.1 - 9.4e-06 24.6 0.0 0.0048 15.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF1894 PF08979.11 OEU15437.1 - 0.0039 17.5 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1894) PPR_2 PF13041.6 OEU15438.1 - 7.6e-22 77.3 4.9 0.0032 17.6 0.0 10.3 7 3 3 10 10 10 6 PPR repeat family PPR_long PF17177.4 OEU15438.1 - 3.1e-18 65.9 0.6 0.00026 20.4 0.0 4.6 3 2 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 OEU15438.1 - 5e-15 55.3 0.1 0.026 14.6 0.0 9.4 3 3 8 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU15438.1 - 7.2e-15 54.4 4.8 0.0015 18.2 0.0 10.1 10 0 0 10 10 10 2 PPR repeat PPR PF01535.20 OEU15438.1 - 3e-06 27.1 19.6 0.01 16.1 0.0 11.0 11 2 0 11 11 11 1 PPR repeat COG7 PF10191.9 OEU15439.1 - 9.8e-07 27.4 0.0 1.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Pkinase PF00069.25 OEU15440.1 - 3.7e-48 164.2 0.0 8.1e-48 163.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15440.1 - 9.2e-36 123.4 0.1 1.3e-34 119.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU15440.1 - 5.4e-05 22.1 0.1 6.9e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OEU15440.1 - 0.0015 17.6 0.8 0.0022 17.0 0.8 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OEU15440.1 - 0.0099 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU15440.1 - 0.041 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OEU15440.1 - 0.073 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_2d PF01409.20 OEU15441.1 - 3.1e-86 288.8 0.0 4.4e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OEU15441.1 - 1.8e-14 53.8 0.6 1.1e-13 51.2 0.5 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 OEU15441.1 - 6.6e-07 29.0 0.0 2.3e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 OEU15441.1 - 8.9e-07 28.6 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OEU15441.1 - 0.00022 20.4 0.0 0.00062 18.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 OEU15441.1 - 0.0033 17.4 2.5 0.0076 16.2 2.5 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 PB1 PF00564.24 OEU15441.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain UPF0020 PF01170.18 OEU15442.1 - 6e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 OEU15442.1 - 0.00055 19.6 0.1 0.0025 17.5 0.1 1.9 1 1 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 OEU15442.1 - 0.02 14.6 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.8 OEU15442.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa N6_N4_Mtase PF01555.18 OEU15442.1 - 0.027 14.2 0.0 2.1 8.0 0.0 2.6 2 1 0 2 2 2 0 DNA methylase N6_Mtase PF02384.16 OEU15442.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase N6-adenineMlase PF10237.9 OEU15442.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DUF1943 PF09172.11 OEU15442.1 - 0.19 10.9 0.0 3.4 6.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) TPR_2 PF07719.17 OEU15443.1 - 1.2e-24 84.3 18.3 3.6e-05 23.6 0.1 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15443.1 - 1.3e-19 69.1 12.2 9.6e-05 22.0 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OEU15443.1 - 4.3e-19 67.6 21.2 0.0047 17.6 0.1 9.0 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15443.1 - 1.4e-18 65.5 12.4 0.05 13.8 0.1 7.8 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 OEU15443.1 - 1.3e-14 54.5 27.1 0.0057 17.1 0.1 6.8 5 1 3 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 OEU15443.1 - 1.5e-13 51.2 19.1 0.0083 16.8 0.0 6.5 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 OEU15443.1 - 1e-10 41.8 19.6 0.09 13.1 0.3 7.1 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU15443.1 - 1.7e-10 40.1 6.2 0.056 13.5 0.3 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU15443.1 - 8.2e-10 38.2 6.5 0.01 15.5 0.0 6.5 5 1 2 7 7 7 2 TPR repeat TPR_9 PF13371.6 OEU15443.1 - 2.8e-07 30.6 12.0 0.58 10.3 0.9 6.2 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 OEU15443.1 - 6.5e-07 29.3 14.7 0.75 10.3 0.1 8.4 8 1 1 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU15443.1 - 5e-06 26.6 8.9 0.14 12.4 0.5 5.5 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OEU15443.1 - 3.2e-05 24.3 14.6 0.074 13.7 0.1 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU15443.1 - 3.9e-05 23.0 1.4 0.0018 17.7 0.0 3.5 4 0 0 4 4 4 1 SHNi-TPR Vps39_1 PF10366.9 OEU15443.1 - 0.0094 16.2 0.2 0.57 10.5 0.1 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 NRBF2_MIT PF17169.4 OEU15443.1 - 0.016 15.4 2.8 0.83 9.9 0.1 3.4 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 DUF4919 PF16266.5 OEU15443.1 - 0.019 14.9 1.8 3.3 7.6 0.0 3.8 3 2 2 5 5 5 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 OEU15443.1 - 0.049 13.5 10.3 0.36 10.8 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 OEU15443.1 - 0.05 13.6 5.5 0.092 12.8 0.3 3.4 3 1 0 3 3 2 0 Protein of unknown function (DUF627) BTAD PF03704.17 OEU15443.1 - 0.068 13.6 7.7 0.11 13.0 2.9 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.10 OEU15443.1 - 0.08 11.9 2.3 4.1 6.3 0.3 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 OEU15443.1 - 0.09 13.5 12.1 0.91 10.3 0.2 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.20 OEU15443.1 - 0.12 12.7 0.3 50 4.5 0.1 3.6 3 0 0 3 3 3 0 PPR repeat MIT PF04212.18 OEU15443.1 - 0.25 11.5 11.9 3.3 7.8 0.2 4.9 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 OEU15443.1 - 0.59 10.2 3.4 2.6 8.2 0.0 3.4 5 1 0 5 5 4 0 MAS20 protein import receptor DUF3813 PF12758.7 OEU15443.1 - 2.9 8.3 6.3 25 5.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) Sel1 PF08238.12 OEU15444.1 - 3.5e-14 52.9 0.0 7.3e-05 23.3 0.0 4.9 5 0 0 5 5 5 4 Sel1 repeat Steroid_dh PF02544.16 OEU15445.1 - 2.4e-22 79.6 1.3 2.4e-22 79.6 1.3 1.9 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OEU15445.1 - 4.8e-06 26.3 0.4 7.3e-06 25.7 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OEU15445.1 - 0.00026 21.3 2.0 0.00026 21.3 2.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 OEU15445.1 - 1.3 9.5 4.4 0.56 10.7 0.1 2.3 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEP_mutase PF13714.6 OEU15446.1 - 4.7e-42 144.1 0.0 5.9e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OEU15446.1 - 9.6e-12 44.1 0.1 1.5e-10 40.2 0.0 2.0 1 1 1 2 2 2 1 Isocitrate lyase family Pantoate_transf PF02548.15 OEU15446.1 - 1e-05 25.1 0.0 6.2e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 Ketopantoate hydroxymethyltransferase DUF4392 PF14336.6 OEU15446.1 - 0.055 12.9 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) adh_short_C2 PF13561.6 OEU15448.1 - 3.3e-37 128.3 0.3 3.8e-37 128.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU15448.1 - 4.4e-18 65.5 0.9 5.4e-18 65.2 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 OEU15448.1 - 0.003 17.0 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TTC5_OB PF16669.5 OEU15448.1 - 0.14 11.8 0.0 0.69 9.6 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain DER1 PF04511.15 OEU15449.1 - 2.2e-32 112.6 5.2 2.5e-32 112.3 5.2 1.0 1 0 0 1 1 1 1 Der1-like family PsbP PF01789.16 OEU15450.1 - 0.0039 17.3 0.0 0.0094 16.1 0.0 1.7 1 1 0 1 1 1 1 PsbP zf-MYND PF01753.18 OEU15451.1 - 9.4e-07 28.8 9.8 9.4e-07 28.8 9.8 2.1 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.7 OEU15451.1 - 0.066 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OEU15451.1 - 0.093 12.6 0.1 0.093 12.6 0.1 1.9 2 0 0 2 2 2 0 F-box domain SR-25 PF10500.9 OEU15451.1 - 9.9 5.7 14.2 19 4.8 14.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aminotran_4 PF01063.19 OEU15452.1 - 8.4e-34 117.4 0.0 1.1e-33 117.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Nefa_Nip30_N PF10187.9 OEU15453.1 - 5.4e-10 39.6 1.9 5.4e-10 39.6 1.9 2.7 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 zf-LYAR PF08790.11 OEU15454.1 - 2e-14 53.2 8.7 2.4e-14 52.9 2.6 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger RRN3 PF05327.11 OEU15454.1 - 0.00086 18.0 5.4 0.00095 17.8 5.4 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 zf-ACC PF17848.1 OEU15454.1 - 0.0025 17.8 0.6 0.0081 16.2 0.6 2.0 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain UCH PF00443.29 OEU15454.1 - 0.032 13.7 4.8 0.046 13.2 4.8 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AAA_assoc_C PF09821.9 OEU15454.1 - 0.12 12.9 4.2 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 C-terminal AAA-associated domain CNDH2_N PF06278.11 OEU15454.1 - 0.23 11.7 7.1 0.52 10.5 7.1 1.7 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal IBR PF01485.21 OEU15454.1 - 0.27 11.5 7.8 0.96 9.7 7.8 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 OEU15454.1 - 0.45 10.5 8.7 1.5 8.8 7.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4093 PF13331.6 OEU15454.1 - 1.4 9.4 8.9 4.5 7.8 8.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4093) DUF2018 PF09442.10 OEU15454.1 - 1.8 9.6 6.7 2.5 9.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) C1_4 PF07975.12 OEU15454.1 - 2.8 8.3 9.5 8.2 6.8 8.4 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain Slu7 PF11708.8 OEU15454.1 - 4.6 6.9 20.2 11 5.7 17.9 2.0 1 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Nup54_C PF18437.1 OEU15454.1 - 7.3 6.6 9.5 1e+02 2.9 7.6 2.4 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain Abhydrolase_1 PF00561.20 OEU15457.1 - 2.5e-08 33.9 0.0 0.001 18.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU15457.1 - 1.4e-07 31.1 0.0 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU15457.1 - 3.3e-06 27.9 0.0 6.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OEU15457.1 - 4.3e-06 26.5 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Peptidase_S10 PF00450.22 OEU15457.1 - 1.3e-05 24.9 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.13 OEU15457.1 - 2.1e-05 24.5 0.0 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Acyltransferase PF01553.21 OEU15457.1 - 2.9e-05 23.7 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 OEU15457.1 - 3.7e-05 22.8 0.0 8.6e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol acyltransferase BAAT_C PF08840.11 OEU15457.1 - 0.012 15.5 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 OEU15457.1 - 0.013 15.3 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 OEU15457.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 OEU15457.1 - 0.029 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 OEU15457.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 OEU15457.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TP_methylase PF00590.20 OEU15458.1 - 6.1e-26 91.7 0.1 1.4e-25 90.5 0.1 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases IMD PF08397.11 OEU15458.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain Rhomboid PF01694.22 OEU15459.1 - 5.8e-35 120.5 8.2 7.5e-35 120.1 8.2 1.1 1 0 0 1 1 1 1 Rhomboid family NodZ PF05830.11 OEU15461.1 - 9.2e-11 41.1 0.0 1.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) Mad3_BUB1_I_2 PF17014.5 OEU15462.1 - 0.11 12.6 0.7 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein SSP160 PF06933.11 OEU15462.1 - 3.2 5.9 5.0 6.4 4.8 5.0 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4611 PF15387.6 OEU15464.1 - 0.25 11.6 10.8 0.98 9.7 1.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF4484 PF14831.6 OEU15464.1 - 1.1 9.2 7.4 0.25 11.3 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) PBP1_TM PF14812.6 OEU15464.1 - 1.2 9.6 13.0 4.8 7.6 1.8 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfotransfer_3 PF13469.6 OEU15465.1 - 1.5e-05 25.5 0.0 4.5e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase family Orbi_VP5 PF00901.17 OEU15465.1 - 1.6 7.1 5.3 0.36 9.2 0.1 2.0 2 1 0 2 2 2 0 Orbivirus outer capsid protein VP5 DUF4467 PF14729.6 OEU15465.1 - 2.9 8.3 11.2 0.23 11.9 6.0 1.9 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) GN3L_Grn1 PF08701.11 OEU15466.1 - 2.9e-18 65.7 14.5 6.4e-18 64.6 14.5 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OEU15466.1 - 6.8e-17 61.6 1.9 9.3e-13 48.3 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU15466.1 - 1.3e-07 31.3 0.2 2.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OEU15466.1 - 0.00024 21.1 0.7 0.43 10.5 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OEU15466.1 - 0.0007 19.2 0.3 0.033 13.7 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DNA_binding_2 PF13724.6 OEU15466.1 - 0.019 15.4 0.1 0.063 13.7 0.1 1.9 1 0 0 1 1 1 0 DNA-binding domain Dynamin_N PF00350.23 OEU15466.1 - 0.041 13.9 4.9 0.81 9.7 0.1 3.4 2 2 1 3 3 3 0 Dynamin family cobW PF02492.19 OEU15466.1 - 0.065 12.8 1.4 0.17 11.4 0.4 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OEU15466.1 - 0.35 11.2 2.7 3.7 7.9 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Amnionless PF14828.6 OEU15466.1 - 0.69 8.7 5.6 0.15 10.9 0.3 2.0 2 0 0 2 2 2 0 Amnionless Arf PF00025.21 OEU15466.1 - 5 6.5 6.9 2.9 7.3 0.0 2.9 4 0 0 4 4 4 0 ADP-ribosylation factor family TIM PF00121.18 OEU15467.1 - 2.5e-74 249.7 0.0 2.9e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase COX14 PF14880.6 OEU15468.1 - 0.044 13.6 0.2 0.066 13.1 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly LapA_dom PF06305.11 OEU15468.1 - 0.054 13.3 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pox_A14 PF05767.12 OEU15468.1 - 0.064 13.4 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 SARAF PF06682.12 OEU15468.1 - 0.1 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TMCCDC2 PF15844.5 OEU15468.1 - 0.21 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Nop PF01798.18 OEU15469.1 - 1.3e-57 194.9 0.5 1.3e-57 194.9 0.5 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OEU15469.1 - 1.1e-19 71.5 12.8 1.1e-19 71.5 12.8 2.1 2 0 0 2 2 2 1 Prp31 C terminal domain PPR_2 PF13041.6 OEU15470.1 - 3.1e-07 30.5 0.4 5.4e-05 23.3 0.0 3.8 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 OEU15470.1 - 5.9e-07 29.5 0.0 0.00072 19.6 0.0 4.4 5 0 0 5 5 5 1 Pentatricopeptide repeat domain Cytochrom_C552 PF02335.15 OEU15470.1 - 0.021 13.8 0.4 0.12 11.3 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c552 PPR_long PF17177.4 OEU15470.1 - 0.048 13.0 0.1 0.68 9.3 0.0 2.5 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Gluconate_2-dh3 PF13618.6 OEU15470.1 - 0.18 12.0 1.0 2.2 8.5 0.1 3.0 3 1 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 WD40 PF00400.32 OEU15471.1 - 4.8e-17 62.0 26.7 0.001 19.9 1.5 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat HA PF03457.14 OEU15472.1 - 8.2e-37 125.4 8.5 3.8e-18 65.6 1.0 2.1 2 0 0 2 2 2 2 Helicase associated domain HAGH_C PF16123.5 OEU15472.1 - 0.046 14.2 0.5 0.16 12.5 0.1 2.1 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus RecX PF02631.16 OEU15472.1 - 0.097 13.1 1.3 2.3 8.7 0.1 2.1 2 0 0 2 2 2 0 RecX family DUF4695 PF15766.5 OEU15474.1 - 0.0098 16.1 0.1 0.02 15.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4695) Imm26 PF15428.6 OEU15474.1 - 0.081 13.2 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 26 ClpS PF02617.17 OEU15475.1 - 7.9e-16 57.6 0.0 1.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS G10 PF01125.17 OEU15475.1 - 0.057 13.2 0.2 0.074 12.8 0.2 1.1 1 0 0 1 1 1 0 G10 protein ABC1 PF03109.16 OEU15476.1 - 8.2e-30 103.4 0.1 2e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU15476.1 - 1.6e-06 28.3 2.8 0.00056 19.9 1.4 3.1 2 1 0 3 3 3 2 Phosphotransferase enzyme family IF4E PF01652.18 OEU15477.1 - 1.3e-52 177.8 1.3 1.6e-52 177.5 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ELP6 PF09807.9 OEU15478.1 - 8.9e-05 22.0 0.0 0.054 12.9 0.0 3.0 2 1 0 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 OEU15478.1 - 0.12 11.8 0.1 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Elongator subunit Iki1 DUF3372 PF11852.8 OEU15478.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Chorion_2 PF03964.15 OEU15478.1 - 2.5 9.0 9.9 3.9 8.4 3.8 2.4 2 0 0 2 2 2 0 Chorion family 2 MFS_1 PF07690.16 OEU15479.1 - 4.5e-24 85.0 10.2 4.5e-24 85.0 10.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU15479.1 - 9.2e-08 31.4 7.3 1.9e-07 30.3 7.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter RVT_2 PF07727.14 OEU15480.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NKAIN PF05640.14 OEU15482.1 - 0.0048 16.2 3.7 0.0061 15.8 3.7 1.2 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Herpes_US9 PF06072.11 OEU15482.1 - 1.3 9.0 5.8 3 7.8 0.5 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DASH_Duo1 PF08651.10 OEU15483.1 - 0.092 12.5 1.1 0.31 10.8 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 SesA PF17107.5 OEU15483.1 - 0.1 12.8 4.1 2.2 8.5 0.9 3.9 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Beach PF02138.18 OEU15484.1 - 7.8e-92 307.6 0.0 9.3e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OEU15484.1 - 3.5e-09 36.7 0.1 5.9e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Peptidase_M48 PF01435.18 OEU15485.1 - 4.6e-31 108.1 0.0 6.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cecropin PF00272.19 OEU15485.1 - 0.028 14.1 0.5 0.065 13.0 0.5 1.5 1 0 0 1 1 1 0 Cecropin family Pox_P4B PF03292.14 OEU15486.1 - 0.07 11.4 0.0 0.098 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF4220 PF13968.6 OEU15487.1 - 0.094 12.1 1.6 0.11 11.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4064 PF13273.6 OEU15487.1 - 0.13 12.6 4.8 0.21 11.9 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) MlaE PF02405.16 OEU15487.1 - 1.5 8.4 8.3 0.24 11.0 4.3 1.6 2 0 0 2 2 2 0 Permease MlaE zf-MYND PF01753.18 OEU15488.1 - 3.3e-07 30.3 41.7 0.0016 18.5 41.7 3.7 1 1 0 1 1 1 1 MYND finger PHD PF00628.29 OEU15489.1 - 3.5e-07 30.0 8.4 7e-07 29.0 8.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 OEU15489.1 - 0.00087 19.4 2.4 0.002 18.2 2.4 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OEU15489.1 - 0.0011 19.2 3.6 0.0032 17.7 3.6 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OEU15489.1 - 0.0095 15.5 2.9 0.0095 15.5 2.9 1.7 2 0 0 2 2 2 1 PHD-finger DUF4364 PF14277.6 OEU15489.1 - 0.024 14.4 1.5 0.15 11.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Importin_rep PF18773.1 OEU15489.1 - 0.033 13.9 0.2 0.097 12.4 0.2 1.7 1 0 0 1 1 1 0 Importin 13 repeat RNase_E_G PF10150.9 OEU15489.1 - 0.043 13.2 0.6 0.076 12.4 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease E/G family Hema_HEFG PF02710.14 OEU15489.1 - 0.045 14.0 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein PhnA_Zn_Ribbon PF08274.12 OEU15489.1 - 0.053 13.5 1.3 0.12 12.4 1.3 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon C1_2 PF03107.16 OEU15489.1 - 0.28 11.5 7.2 0.68 10.3 3.9 2.3 2 0 0 2 2 2 0 C1 domain zf-RING-like PF08746.11 OEU15489.1 - 3.7 7.9 7.5 6.5 7.1 6.5 2.0 1 1 1 2 2 2 0 RING-like domain Adap_comp_sub PF00928.21 OEU15493.1 - 6.5e-05 22.4 0.1 8.3e-05 22.1 0.1 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF1824 PF08854.10 OEU15494.1 - 9.4e-12 44.9 0.0 9.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1824) Stevor PF17410.2 OEU15494.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame IMUP PF15761.5 OEU15494.1 - 2 9.1 10.3 3.7 8.3 10.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein RAP1 PF07218.11 OEU15494.1 - 3.1 6.0 8.3 3.6 5.8 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nup88 PF10168.9 OEU15495.1 - 2.2e-05 22.5 2.1 4.2e-05 21.6 2.1 1.6 1 0 0 1 1 1 1 Nuclear pore component CxC1 PF18802.1 OEU15495.1 - 0.007 16.5 0.2 0.081 13.1 0.0 2.4 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases FAM76 PF16046.5 OEU15495.1 - 0.023 14.0 5.2 0.036 13.4 5.2 1.2 1 0 0 1 1 1 0 FAM76 protein A_deaminase PF00962.22 OEU15496.1 - 3.5e-77 259.9 0.0 3.9e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase OAF PF14941.6 OEU15496.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, Out at first MS_channel PF00924.18 OEU15498.1 - 1.2e-14 54.3 0.1 2.2e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel dCMP_cyt_deam_1 PF00383.23 OEU15499.1 - 5.1e-15 55.2 0.6 6.5e-15 54.8 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OEU15499.1 - 3.7e-10 39.7 0.3 4.7e-10 39.4 0.3 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 OEU15499.1 - 0.0038 17.3 0.0 0.0047 17.0 0.0 1.1 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 OEU15499.1 - 0.0074 16.4 0.0 0.0093 16.1 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 OEU15499.1 - 0.0092 16.1 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 APOBEC3 NAD1 PF18778.1 OEU15499.1 - 0.023 14.8 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 AID PF18767.1 OEU15499.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase SNAD4 PF18750.1 OEU15499.1 - 0.06 13.5 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 OEU15499.1 - 0.065 13.1 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain CheW PF01584.19 OEU15499.1 - 0.075 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 CheW-like domain Bd3614-deam PF14439.6 OEU15499.1 - 0.08 13.0 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase PPR_2 PF13041.6 OEU15500.1 - 1.6e-18 66.6 2.4 0.00048 20.3 0.1 8.7 5 3 3 8 8 8 6 PPR repeat family PPR_3 PF13812.6 OEU15500.1 - 4.8e-12 45.8 3.1 0.0018 18.3 0.0 7.3 5 2 1 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU15500.1 - 4.7e-10 39.2 0.7 0.027 13.8 0.0 4.3 2 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OEU15500.1 - 2.2e-09 36.9 0.1 3.6 7.4 0.0 7.4 7 0 0 7 7 7 2 PPR repeat PPR PF01535.20 OEU15500.1 - 6e-07 29.3 12.8 0.15 12.4 0.0 8.3 9 1 0 9 9 9 2 PPR repeat Vps23_core PF09454.10 OEU15500.1 - 0.069 13.1 0.1 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Vps23 core domain EH_Signature PF15611.6 OEU15500.1 - 0.072 12.5 0.3 0.3 10.5 0.0 2.1 3 0 0 3 3 3 0 EH_Signature domain DUF2779 PF11074.8 OEU15500.1 - 0.94 10.0 3.2 2.1 8.8 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function(DUF2779) Ribosomal_L13 PF00572.18 OEU15501.1 - 3e-06 27.5 0.7 7.5e-05 23.0 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 HisG PF01634.18 OEU15502.1 - 6.6e-54 182.2 0.5 8.7e-54 181.8 0.5 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OEU15502.1 - 1.2e-19 70.2 0.1 3.3e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 OEU15502.1 - 0.0035 17.3 0.2 0.0053 16.7 0.2 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 OEU15502.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 OEU15502.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 LysR substrate binding domain Ycf66_N PF07444.11 OEU15503.1 - 0.099 12.8 0.2 0.099 12.8 0.2 2.4 3 0 0 3 3 3 0 Ycf66 protein N-terminus U-box PF04564.15 OEU15504.1 - 3.2e-17 62.4 0.0 3.5e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OEU15504.1 - 1.3e-08 34.5 0.1 1.4e-07 31.2 0.1 1.9 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OEU15504.1 - 0.00037 20.3 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU15504.1 - 0.0023 18.2 0.0 0.0035 17.6 0.0 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU15504.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU15504.1 - 0.0059 16.6 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OEU15504.1 - 0.0067 16.7 0.0 0.0087 16.4 0.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-NOSIP PF15906.5 OEU15504.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.4 1 1 1 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein T3SS_NleG PF06416.12 OEU15504.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 1 0 1 1 1 0 Effector protein NleG Mpv17_PMP22 PF04117.12 OEU15505.1 - 2.2e-19 69.4 4.0 2.2e-19 69.4 4.0 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family GCV_H PF01597.19 OEU15506.1 - 5.6e-44 148.9 0.0 6.8e-44 148.7 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OEU15506.1 - 9.8e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 OEU15506.1 - 0.00014 21.8 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 OEU15506.1 - 0.03 14.1 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 zf-primase PF09329.11 OEU15507.1 - 7e-05 22.5 4.4 7e-05 22.5 4.4 2.5 2 1 0 2 2 2 1 Primase zinc finger Vps39_2 PF10367.9 OEU15507.1 - 0.014 15.8 0.7 0.014 15.8 0.7 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_jaz PF12171.8 OEU15507.1 - 6.7 7.1 6.6 0.54 10.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Galactosyl_T PF01762.21 OEU15509.1 - 0.0044 16.9 0.1 0.017 14.9 0.0 1.9 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_25 PF01755.17 OEU15509.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-MYND PF01753.18 OEU15510.1 - 0.002 18.2 12.3 0.0048 17.0 12.3 1.7 1 0 0 1 1 1 1 MYND finger CENP-B_dimeris PF09026.10 OEU15510.1 - 0.058 13.8 3.4 0.11 13.0 0.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PolC_DP2 PF03833.13 OEU15510.1 - 1.7 6.4 4.7 2.4 5.9 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Trypsin PF00089.26 OEU15511.1 - 2.2e-42 145.3 0.2 2.9e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU15511.1 - 0.0087 17.0 0.0 0.017 16.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain NAD_binding_1 PF00175.21 OEU15512.1 - 5e-14 52.9 0.4 1.3e-13 51.6 0.4 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 OEU15512.1 - 0.00063 19.4 0.1 0.011 15.3 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain B3 PF02362.21 OEU15512.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 B3 DNA binding domain NAD_binding_6 PF08030.12 OEU15512.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Ank_2 PF12796.7 OEU15514.1 - 2e-09 37.9 0.2 0.057 14.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU15514.1 - 8.4e-09 35.5 0.4 0.91 9.9 0.1 4.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU15514.1 - 2.9e-08 33.8 1.4 0.17 12.4 0.0 5.0 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OEU15514.1 - 8.5e-08 32.6 0.6 0.9 10.2 0.0 5.6 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU15514.1 - 5.1e-07 29.5 0.5 0.47 11.2 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Abhydrolase_1 PF00561.20 OEU15515.1 - 7.5e-14 52.0 0.1 8.4e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU15515.1 - 5e-13 48.9 0.0 6.3e-08 32.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU15515.1 - 1.5e-07 31.1 0.0 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF818 PF05677.12 OEU15515.1 - 5.9e-07 28.8 0.0 8.1e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 OEU15515.1 - 6.7e-07 30.1 0.0 0.00019 22.1 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 OEU15515.1 - 0.00053 19.6 0.0 0.0019 17.8 0.0 1.8 1 1 1 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OEU15515.1 - 0.0069 16.2 0.0 0.021 14.6 0.0 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OEU15515.1 - 0.0089 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OEU15515.1 - 0.025 14.2 0.1 0.05 13.2 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.10 OEU15515.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) FSH1 PF03959.13 OEU15515.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 OEU15515.1 - 0.15 12.0 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PC4 PF02229.16 OEU15516.1 - 2.1e-25 88.1 0.1 3.7e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CAF1A PF12253.8 OEU15516.1 - 0.15 12.3 8.7 0.23 11.6 8.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Sporozoite_P67 PF05642.11 OEU15516.1 - 0.17 9.9 6.2 0.2 9.7 6.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CBFD_NFYB_HMF PF00808.23 OEU15517.1 - 1.3e-09 38.1 0.2 1.6e-09 37.9 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU15517.1 - 0.0045 17.3 0.1 0.0052 17.1 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 OEU15517.1 - 0.075 13.1 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit UQ_con PF00179.26 OEU15518.1 - 2e-46 157.1 0.0 2.4e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU15518.1 - 0.064 13.0 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B eIF-5_eIF-2B PF01873.17 OEU15519.1 - 5.2e-34 116.6 0.0 5.2e-34 116.6 0.0 1.8 2 0 0 2 2 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OEU15519.1 - 8.8e-14 51.4 1.1 8.8e-14 51.4 1.1 2.3 2 0 0 2 2 1 1 eIF4-gamma/eIF5/eIF2-epsilon TERB2 PF15101.6 OEU15519.1 - 0.00056 20.0 3.6 0.00091 19.3 3.6 1.4 1 0 0 1 1 1 1 Telomere-associated protein TERB2 DDHD PF02862.17 OEU15519.1 - 0.0037 17.5 1.4 0.0053 16.9 1.4 1.3 1 0 0 1 1 1 1 DDHD domain PPP4R2 PF09184.11 OEU15519.1 - 0.018 14.7 13.0 0.028 14.0 13.0 1.2 1 0 0 1 1 1 0 PPP4R2 Zn_Tnp_IS1595 PF12760.7 OEU15519.1 - 0.03 14.3 0.3 0.065 13.2 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zip PF02535.22 OEU15519.1 - 0.037 13.2 4.2 0.046 13.0 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.11 OEU15519.1 - 0.064 11.3 10.0 0.087 10.9 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ndc1_Nup PF09531.10 OEU15519.1 - 0.065 11.9 1.8 0.076 11.7 1.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CKAP2_C PF15297.6 OEU15519.1 - 0.068 12.3 13.8 0.1 11.7 13.8 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SAPS PF04499.15 OEU15519.1 - 0.2 10.4 9.5 0.3 9.8 9.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM75 PF14650.6 OEU15519.1 - 0.76 9.3 8.8 1.1 8.7 8.8 1.1 1 0 0 1 1 1 0 FAM75 family RPN2_C PF18004.1 OEU15519.1 - 0.83 9.6 25.5 1.7 8.5 24.0 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_Rpc4 PF05132.14 OEU15519.1 - 1.3 9.4 11.7 2.4 8.6 11.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 OEU15519.1 - 1.4 9.2 23.1 2.5 8.4 23.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.8 OEU15519.1 - 7.9 5.2 22.8 16 4.2 21.8 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 OEU15519.1 - 9.6 4.4 14.8 15 3.7 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OEU15520.1 - 0.026 13.1 9.3 0.031 12.9 9.3 1.0 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 OEU15520.1 - 0.6 10.5 10.3 0.44 11.0 9.1 1.3 1 1 0 1 1 1 0 Fez1 TMPIT PF07851.13 OEU15520.1 - 0.76 9.0 3.9 1.1 8.5 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 OEU15521.1 - 2e-39 135.6 0.0 2.4e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15521.1 - 4.9e-19 68.6 0.0 6.2e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU15521.1 - 1.2e-06 28.7 0.1 0.00052 20.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 OEU15521.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OEU15521.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OEU15521.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU15521.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OEU15521.1 - 0.18 10.7 0.1 0.25 10.2 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OEU15521.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UcrQ PF02939.16 OEU15522.1 - 0.0067 16.3 0.1 0.0084 16.0 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Pkinase PF00069.25 OEU15523.1 - 2.5e-33 115.6 0.0 5.9e-33 114.3 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15523.1 - 8.2e-15 54.8 0.0 3.2e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU15523.1 - 5.4e-06 26.5 0.3 4.3e-05 23.6 0.2 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU15523.1 - 0.0041 16.5 0.1 0.049 12.9 0.1 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OEU15523.1 - 0.038 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GLF PF03275.13 OEU15524.1 - 9.2e-68 228.0 0.6 1.3e-67 227.5 0.6 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 OEU15524.1 - 1.7e-15 57.0 0.1 3.6e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OEU15524.1 - 0.00022 20.7 0.0 0.00069 19.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OEU15524.1 - 0.00031 20.8 0.0 0.017 15.1 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OEU15524.1 - 0.0014 17.9 0.1 0.0028 16.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 OEU15524.1 - 0.0017 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase CRISPR_Cse1 PF09481.10 OEU15524.1 - 0.041 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DAO PF01266.24 OEU15524.1 - 0.051 13.1 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OEU15524.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SOUL PF04832.12 OEU15525.1 - 3.4e-38 131.4 0.3 5.7e-38 130.7 0.3 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein CheR_N PF03705.15 OEU15525.1 - 0.23 11.2 1.9 3 7.7 1.8 2.6 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain DSPc PF00782.20 OEU15526.1 - 2.7e-16 59.6 0.0 3.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OEU15526.1 - 6e-06 26.0 0.0 7.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OEU15526.1 - 0.0061 16.7 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 OEU15526.1 - 0.091 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain ANAPC3 PF12895.7 OEU15527.1 - 0.024 14.8 0.5 0.81 10.0 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OEU15527.1 - 0.035 14.6 0.1 0.1 13.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 OEU15527.1 - 0.072 13.4 0.8 0.21 12.0 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU15527.1 - 0.23 11.6 1.1 8.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU15527.1 - 0.33 11.9 6.2 27 5.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU15527.1 - 1.8 8.5 3.8 10 6.1 0.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 OEU15528.1 - 1.7e-50 171.8 0.0 2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ADK PF00406.22 OEU15529.1 - 1.9e-45 154.7 0.0 2.8e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU15529.1 - 1.2e-18 67.8 0.1 2.3e-18 66.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OEU15529.1 - 1.7e-15 56.7 0.0 3.5e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OEU15529.1 - 8.6e-06 26.3 0.0 1.8e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OEU15529.1 - 0.17 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2796 PF10986.8 OEU15531.1 - 0.024 14.6 1.7 0.054 13.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) GPS2_interact PF15784.5 OEU15531.1 - 0.037 14.5 1.6 0.037 14.5 1.6 2.5 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF2203 PF09969.9 OEU15531.1 - 5.2 7.8 0.0 5.2 7.8 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) SOAR PF16533.5 OEU15531.1 - 7.3 6.6 12.7 5.7 7.0 2.3 3.4 2 1 1 3 3 3 0 STIM1 Orai1-activating region Ssu72 PF04722.13 OEU15532.1 - 1.7e-59 200.6 0.0 1.9e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Hydrolase_4 PF12146.8 OEU15533.1 - 2.2e-10 40.2 0.0 0.00026 20.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU15533.1 - 9.9e-05 21.9 0.0 0.00038 20.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OEU15533.1 - 0.00033 20.4 0.1 0.35 10.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU15533.1 - 0.0025 18.5 1.8 0.06 13.9 0.4 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.14 OEU15533.1 - 0.003 16.9 0.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_2 PF02230.16 OEU15533.1 - 0.018 14.9 0.0 0.042 13.6 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 OEU15533.1 - 0.025 14.2 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) 3HBOH PF10605.9 OEU15533.1 - 0.038 12.2 0.0 0.052 11.8 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) DUF818 PF05677.12 OEU15533.1 - 0.054 12.5 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_4 PF08386.10 OEU15533.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein SNF2_N PF00176.23 OEU15536.1 - 1.4e-69 234.5 0.7 3.5e-69 233.2 0.7 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OEU15536.1 - 1.5e-31 108.8 0.1 1.5e-31 108.8 0.1 3.8 4 0 0 4 4 4 1 SLIDE Helicase_C PF00271.31 OEU15536.1 - 9.7e-18 64.5 0.0 3.6e-17 62.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15536.1 - 3.1e-11 43.6 0.0 3.1e-11 43.6 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU15536.1 - 1.3e-05 25.0 0.1 4.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OEU15536.1 - 3.5e-05 23.1 0.1 3.5e-05 23.1 0.1 3.1 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 SesA PF17107.5 OEU15536.1 - 0.072 13.3 2.2 0.29 11.3 2.2 2.0 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HMG_box PF00505.19 OEU15536.1 - 0.43 11.0 15.7 0.3 11.5 0.2 3.4 3 0 0 3 3 3 0 HMG (high mobility group) box WD40 PF00400.32 OEU15537.1 - 9.2e-14 51.6 12.3 0.02 15.7 0.2 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Sec16_C PF12931.7 OEU15537.1 - 1.1e-11 45.0 1.7 4.6e-10 39.6 1.7 3.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WW PF00397.26 OEU15537.1 - 9.6e-10 38.4 0.3 2.3e-09 37.1 0.3 1.7 1 0 0 1 1 1 1 WW domain ANAPC4_WD40 PF12894.7 OEU15537.1 - 6.6e-06 26.3 0.5 0.0075 16.6 0.6 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 OEU15537.1 - 3.3e-05 23.7 0.0 3.3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Nup84_Nup100 PF04121.13 OEU15537.1 - 0.029 12.5 0.0 0.39 8.8 0.0 2.1 1 1 1 2 2 2 0 Nuclear pore protein 84 / 107 DS PF01916.17 OEU15538.1 - 2.9e-126 420.6 0.0 3.5e-126 420.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase BAF PF02961.14 OEU15538.1 - 0.026 15.0 0.1 0.17 12.4 0.1 2.1 1 1 0 1 1 1 0 Barrier to autointegration factor HEXIM PF15313.6 OEU15538.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein LRR_8 PF13855.6 OEU15539.1 - 1.5e-10 40.7 13.5 0.00018 21.2 1.4 3.4 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU15539.1 - 4.2e-08 33.4 18.8 0.00017 21.9 3.2 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 OEU15539.1 - 0.00055 20.2 0.2 0.0012 19.2 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 OEU15539.1 - 0.071 13.7 20.7 7.2 7.6 0.5 6.7 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 OEU15539.1 - 0.08 12.4 0.8 6.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 OEU15539.1 - 0.47 10.6 11.3 2.2 8.6 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat PH PF00169.29 OEU15540.1 - 7.1e-14 52.2 0.4 2.7e-13 50.3 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OEU15540.1 - 0.00039 20.8 4.5 0.0053 17.2 1.0 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 OEU15540.1 - 0.0069 16.7 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain S1 PF00575.23 OEU15541.1 - 3.7e-10 40.0 2.7 3.7e-10 40.0 0.0 2.6 3 0 0 3 3 3 1 S1 RNA binding domain Hist_deacetyl PF00850.19 OEU15542.1 - 6e-81 272.3 0.0 8.2e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain AAA PF00004.29 OEU15543.1 - 2.1e-34 118.8 0.0 3.3e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU15543.1 - 2.7e-14 52.7 1.0 4.8e-14 51.9 1.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OEU15543.1 - 2.7e-07 31.1 0.2 0.00032 21.1 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OEU15543.1 - 6.8e-07 29.6 0.0 5.1e-05 23.6 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OEU15543.1 - 2.6e-05 24.2 0.0 7.6e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU15543.1 - 6.3e-05 22.5 0.1 0.00012 21.6 0.1 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OEU15543.1 - 0.00015 21.1 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 OEU15543.1 - 0.0016 18.2 1.0 0.0062 16.3 0.2 2.5 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OEU15543.1 - 0.0026 18.1 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 OEU15543.1 - 0.0028 18.2 0.3 0.0093 16.5 0.0 2.1 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OEU15543.1 - 0.0039 17.3 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OEU15543.1 - 0.0073 16.5 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU15543.1 - 0.0076 16.0 0.1 0.019 14.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU15543.1 - 0.0078 16.1 0.1 0.056 13.4 0.0 2.2 2 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 OEU15543.1 - 0.0088 15.8 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 OEU15543.1 - 0.0093 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OEU15543.1 - 0.013 15.2 0.0 0.039 13.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 OEU15543.1 - 0.015 14.8 0.0 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OEU15543.1 - 0.016 15.0 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OEU15543.1 - 0.02 14.8 0.0 0.9 9.4 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OEU15543.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OEU15543.1 - 0.023 15.2 0.1 0.075 13.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_28 PF13521.6 OEU15543.1 - 0.042 14.1 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OEU15543.1 - 0.051 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 OEU15543.1 - 0.066 12.7 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 OEU15543.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU15543.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OEU15543.1 - 0.1 11.9 0.2 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 OEU15543.1 - 0.11 12.9 1.7 0.29 11.5 0.1 2.2 2 1 1 3 3 2 0 AAA domain DUF2075 PF09848.9 OEU15543.1 - 0.13 11.5 0.0 0.63 9.2 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 OEU15543.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PALP PF00291.25 OEU15543.1 - 0.16 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AAA_3 PF07726.11 OEU15543.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CIAPIN1 PF05093.13 OEU15545.1 - 2e-14 53.9 14.2 1.4e-12 48.0 4.5 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1841 PF08897.11 OEU15546.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Vpu PF00558.19 OEU15546.1 - 0.06 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Vpu protein 7TM_GPCR_Srh PF10318.9 OEU15546.1 - 0.066 12.2 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh SGTA_dimer PF16546.5 OEU15547.1 - 0.00036 20.3 0.3 0.00086 19.0 0.3 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA Exo84_C PF16528.5 OEU15547.1 - 0.0047 16.8 6.3 2 8.2 0.0 3.9 5 0 0 5 5 5 2 Exocyst component 84 C-terminal Vps51 PF08700.11 OEU15547.1 - 0.0061 16.6 0.3 0.0061 16.6 0.3 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 OEU15547.1 - 0.018 15.1 0.1 0.018 15.1 0.1 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_11 PF13086.6 OEU15548.1 - 4e-33 115.3 0.1 1.2e-15 58.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OEU15548.1 - 3.4e-06 27.5 0.0 0.0002 21.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU15548.1 - 9.6e-06 25.4 0.0 0.0035 17.1 0.0 2.6 1 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OEU15548.1 - 1.6e-05 24.8 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 OEU15548.1 - 0.0017 18.8 0.7 0.0039 17.6 0.6 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OEU15548.1 - 0.0037 17.8 0.1 0.0047 17.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU15548.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU15548.1 - 0.011 16.2 0.0 0.047 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OEU15548.1 - 0.052 13.0 0.0 2 7.8 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein SEN1_N PF12726.7 OEU15548.1 - 0.056 11.7 0.1 0.067 11.4 0.1 1.1 1 0 0 1 1 1 0 SEN1 N terminal AAA_22 PF13401.6 OEU15548.1 - 0.14 12.4 0.1 0.69 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 OEU15549.1 - 4.4e-43 147.2 0.2 5.3e-43 147.0 0.2 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OEU15549.1 - 0.0038 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OEU15549.1 - 0.018 14.8 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 OEU15549.1 - 0.14 11.5 0.2 0.52 9.6 0.2 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain HAD_2 PF13419.6 OEU15553.1 - 1.4e-17 64.3 0.0 4.2e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU15553.1 - 2.5e-09 37.7 0.0 4e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU15553.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 OEU15553.1 - 0.016 14.9 0.0 0.33 10.7 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU15553.1 - 0.035 14.5 0.0 0.16 12.4 0.0 1.8 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ion_trans PF00520.31 OEU15554.1 - 6.3e-05 22.3 2.2 0.0001 21.6 2.2 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OEU15554.1 - 0.0014 18.5 5.6 0.0033 17.3 5.6 1.6 1 1 0 1 1 1 1 Ion channel IRK PF01007.20 OEU15554.1 - 0.018 14.8 1.4 0.034 14.0 1.4 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain SPT6_acidic PF14632.6 OEU15554.1 - 0.18 12.4 0.3 0.18 12.4 0.3 2.9 3 0 0 3 3 3 0 Acidic N-terminal SPT6 VDE PF07137.11 OEU15556.1 - 4.6e-13 49.3 0.0 5.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain TUDOR PF00567.24 OEU15557.1 - 0.12 12.5 0.1 0.22 11.5 0.0 1.5 2 0 0 2 2 2 0 Tudor domain RNase_HII PF01351.18 OEU15558.1 - 5e-46 157.0 0.0 7.5e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII zf-C3HC4_3 PF13920.6 OEU15558.1 - 0.022 14.6 0.8 0.044 13.7 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Adap_comp_sub PF00928.21 OEU15559.1 - 7.2e-65 219.0 0.0 8.6e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OEU15559.1 - 0.00028 20.8 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 OEU15559.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain WRNPLPNID PF15017.6 OEU15560.1 - 1.6 9.6 4.7 1.7 9.6 0.3 2.6 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Glyco_trans_1_2 PF13524.6 OEU15561.1 - 2.5e-10 40.6 0.0 4.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 RRM_1 PF00076.22 OEU15562.1 - 2e-13 50.0 0.0 4.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FtsJ PF01728.19 OEU15562.1 - 3e-13 50.2 0.1 9.9e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase RRM_7 PF16367.5 OEU15562.1 - 2.6e-05 24.2 0.0 7.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif Methyltransf_25 PF13649.6 OEU15562.1 - 0.1 13.3 0.0 0.5 11.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pet20 PF08692.10 OEU15563.1 - 0.047 14.4 0.9 0.17 12.6 0.0 2.2 2 1 0 2 2 2 0 Mitochondrial protein Pet20 NOA36 PF06524.12 OEU15563.1 - 1.7 7.9 7.4 0.33 10.2 2.9 1.9 2 0 0 2 2 2 0 NOA36 protein BRCT_2 PF16589.5 OEU15564.1 - 0.049 14.0 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AIM24 PF01987.17 OEU15565.1 - 5.8e-60 202.5 1.8 6.5e-60 202.4 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF2917 PF11142.8 OEU15565.1 - 0.18 11.2 0.1 9.9 5.6 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2917) DEAD PF00270.29 OEU15566.1 - 5.9e-34 117.3 0.3 2.4e-33 115.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 OEU15566.1 - 5.2e-23 81.0 0.0 1.1e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OEU15566.1 - 1.8e-22 79.8 0.0 1.2e-21 77.1 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU15566.1 - 0.0039 17.2 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OEU15566.1 - 0.0079 15.4 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase 5-FTHF_cyc-lig PF01812.20 OEU15568.1 - 4.4e-37 127.8 0.0 5.5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF3245 PF11595.8 OEU15569.1 - 0.81 10.2 6.3 0.54 10.7 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Sel1 PF08238.12 OEU15570.1 - 8.7e-30 102.5 2.8 4.2e-08 33.6 0.0 5.2 5 0 0 5 5 5 5 Sel1 repeat Feld-I_B PF09252.10 OEU15570.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Allergen Fel d I-B chain F-box-like PF12937.7 OEU15570.1 - 0.071 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like HA2 PF04408.23 OEU15572.1 - 2.5e-19 69.6 0.0 5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OEU15572.1 - 1.6e-10 41.3 0.0 1.1e-09 38.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU15572.1 - 8.6e-08 32.1 0.1 2e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OEU15572.1 - 3.4e-07 30.5 0.0 9e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OEU15572.1 - 6e-05 23.3 0.0 0.00016 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OEU15572.1 - 0.19 12.2 0.0 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Homeobox_KN PF05920.11 OEU15573.1 - 9.8e-14 51.0 0.0 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OEU15573.1 - 6.9e-06 25.8 0.1 9.5e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 Homeodomain SNF2_N PF00176.23 OEU15574.1 - 4.6e-72 242.7 0.1 7.4e-72 242.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU15574.1 - 1.5e-19 70.4 0.0 2.2e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 OEU15574.1 - 1.2e-16 60.5 0.1 4e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Bromodomain ResIII PF04851.15 OEU15574.1 - 2.4e-12 47.2 0.0 1.1e-11 45.0 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SnAC PF14619.6 OEU15574.1 - 3.7e-09 37.1 0.8 9.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex AAA_22 PF13401.6 OEU15574.1 - 0.076 13.3 0.9 5.6 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain BolA PF01722.18 OEU15575.1 - 7.1e-13 48.6 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Macro PF01661.21 OEU15575.1 - 0.087 12.9 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Macro domain Mg_chelatase PF01078.21 OEU15576.1 - 3.3e-13 49.5 0.3 4.7e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 OEU15576.1 - 1.6e-12 48.0 0.0 8.9e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_lid_2 PF17863.1 OEU15576.1 - 3e-11 43.0 0.0 9.7e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain Sigma54_activat PF00158.26 OEU15576.1 - 4e-06 26.6 0.0 0.018 14.7 0.0 2.6 3 0 0 3 3 3 2 Sigma-54 interaction domain VWA PF00092.28 OEU15576.1 - 4.3e-06 27.1 0.0 8.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MCM PF00493.23 OEU15576.1 - 2.4e-05 23.5 0.0 0.00022 20.4 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 OEU15576.1 - 0.00038 20.4 0.0 0.078 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 OEU15576.1 - 0.0021 18.1 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 OEU15576.1 - 0.0086 16.5 2.6 0.044 14.2 0.4 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 OEU15576.1 - 0.019 14.5 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mito_fiss_reg PF05308.11 OEU15576.1 - 0.1 12.6 6.6 0.033 14.3 3.5 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator CDC45 PF02724.14 OEU15576.1 - 0.11 10.8 2.3 0.18 10.0 2.3 1.3 1 0 0 1 1 1 0 CDC45-like protein F-protein PF00469.20 OEU15576.1 - 0.15 11.6 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef CAP_N PF01213.19 OEU15576.1 - 0.18 11.3 5.9 0.45 10.0 5.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal VIR_N PF15912.5 OEU15576.1 - 0.3 10.7 8.1 0.85 9.2 8.1 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal CCDC53 PF10152.9 OEU15576.1 - 2.7 8.4 7.9 0.086 13.3 1.4 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Retrotran_gag_2 PF14223.6 OEU15577.1 - 0.0044 16.7 1.3 0.0092 15.6 0.0 2.1 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type IFT20 PF14931.6 OEU15577.1 - 0.013 15.7 1.9 0.035 14.3 0.8 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 PspA_IM30 PF04012.12 OEU15577.1 - 0.27 10.8 5.1 3.6 7.1 5.0 2.2 1 1 0 1 1 1 0 PspA/IM30 family Rad17 PF03215.15 OEU15578.1 - 4.6e-22 78.9 0.1 9.9e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 OEU15578.1 - 7.5e-06 26.4 0.0 4.1e-05 24.0 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU15578.1 - 0.00013 22.4 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU15578.1 - 0.00023 21.5 0.1 0.00088 19.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 OEU15578.1 - 0.0009 19.8 0.0 0.0033 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU15578.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 OEU15578.1 - 0.0038 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 OEU15578.1 - 0.0047 17.4 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 OEU15578.1 - 0.005 17.0 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OEU15578.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 OEU15578.1 - 0.014 15.5 0.6 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_17 PF13207.6 OEU15578.1 - 0.019 15.4 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OEU15578.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OEU15578.1 - 0.02 15.3 0.1 0.093 13.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OEU15578.1 - 0.035 13.8 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OEU15578.1 - 0.038 14.4 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 OEU15578.1 - 0.052 13.5 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 OEU15578.1 - 0.059 13.3 0.2 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 OEU15578.1 - 0.07 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 OEU15578.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 OEU15578.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain SOBP PF15279.6 OEU15579.1 - 4.9 7.7 6.4 7.3 7.1 6.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0160 PF03690.13 OEU15580.1 - 1.7e-119 399.1 0.0 2e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DJ-1_PfpI PF01965.24 OEU15581.1 - 1.9e-38 131.8 0.1 2.2e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family DAO PF01266.24 OEU15583.1 - 6.7e-08 32.5 0.0 1.9e-05 24.4 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU15583.1 - 0.00011 21.4 0.0 0.0026 16.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU15583.1 - 0.031 13.5 0.1 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU15583.1 - 0.064 11.9 0.0 7.3 5.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 OEU15583.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF615 PF04751.14 OEU15584.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Methyltransf_16 PF10294.9 OEU15585.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase NOA36 PF06524.12 OEU15586.1 - 0.25 10.6 9.6 0.32 10.3 9.6 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OEU15586.1 - 0.94 9.2 13.1 1.1 9.0 13.1 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 OEU15586.1 - 1.6 9.2 15.4 2.1 8.8 15.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRS4 PF10422.9 OEU15586.1 - 1.6 8.2 4.7 1.8 8.1 4.7 1.0 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DNA_pol_phi PF04931.13 OEU15586.1 - 4.3 5.3 13.0 5 5.1 13.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Methyltr_RsmB-F PF01189.17 OEU15587.1 - 1.4e-70 237.0 0.0 2.1e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OEU15587.1 - 3.6e-07 30.6 0.0 9.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OEU15587.1 - 1.2e-06 28.7 0.1 2.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 OEU15587.1 - 0.0008 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mg_chelatase_C PF13335.6 OEU15587.1 - 0.065 13.9 0.0 0.3 11.7 0.0 2.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal ALMS_motif PF15309.6 OEU15587.1 - 5.5 7.5 12.1 0.25 11.8 3.3 2.5 2 0 0 2 2 2 0 ALMS motif MFS_1 PF07690.16 OEU15588.1 - 5.4e-28 97.9 37.1 5.4e-28 97.9 37.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU15588.1 - 3.3e-07 29.5 5.6 3.3e-07 29.5 5.6 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 OEU15589.1 - 2.4e-49 168.3 0.0 2.7e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 OEU15590.1 - 3.7e-05 23.9 2.0 0.011 15.9 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU15590.1 - 0.00034 20.5 8.3 0.18 12.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15590.1 - 0.0008 19.4 2.7 9.4 6.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15590.1 - 0.003 17.3 5.5 0.77 9.7 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU15590.1 - 0.018 15.6 0.3 7.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 OEU15590.1 - 0.023 14.8 0.2 11 6.1 0.2 2.8 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 OEU15590.1 - 0.068 13.8 2.7 49 4.9 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU15590.1 - 0.091 12.8 0.0 0.46 10.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU15590.1 - 0.15 11.9 3.1 1.9 8.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU15590.1 - 0.19 12.6 4.6 8.2 7.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 OEU15591.1 - 2.1e-70 237.4 0.0 3e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OEU15591.1 - 1.1e-31 110.3 0.0 1.9e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OEU15591.1 - 0.00053 19.7 0.3 0.15 11.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU15591.1 - 0.00085 18.6 0.2 0.19 11.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OEU15591.1 - 0.0065 15.6 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OEU15591.1 - 0.017 15.3 0.2 0.048 13.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU15591.1 - 0.026 15.1 0.1 6.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LAMTOR5 PF16672.5 OEU15592.1 - 4e-13 49.1 1.6 8.1e-12 44.9 1.6 2.1 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 YiiD_C PF09500.10 OEU15592.1 - 0.03 14.2 0.3 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) Glycos_transf_4 PF00953.21 OEU15593.1 - 1.9e-36 125.4 13.1 1.9e-36 125.4 13.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 MFS_1 PF07690.16 OEU15594.1 - 5.5e-17 61.7 17.2 8.3e-12 44.7 0.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OEU15594.1 - 4.2e-10 39.5 7.0 4.2e-10 39.5 7.0 2.5 2 0 0 2 2 2 1 Nodulin-like DUF872 PF05915.12 OEU15594.1 - 0.049 13.8 0.1 0.049 13.8 0.1 3.9 5 0 0 5 5 5 0 Eukaryotic protein of unknown function (DUF872) Cupin_4 PF08007.12 OEU15595.1 - 3.2e-13 49.9 0.1 4.4e-12 46.1 0.1 2.3 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU15595.1 - 2.4e-12 47.1 0.0 9e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 OEU15595.1 - 0.00036 20.2 0.1 0.0015 18.2 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 OEU15595.1 - 0.15 11.8 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Lipase_3 PF01764.25 OEU15596.1 - 6.6e-14 52.0 0.0 2.4e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 OEU15596.1 - 0.0093 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CEP44 PF15007.6 OEU15596.1 - 0.062 13.5 0.1 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 MMR_HSR1 PF01926.23 OEU15599.1 - 4.7e-18 65.3 0.2 1.4e-17 63.8 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase KH_2 PF07650.17 OEU15599.1 - 1.6e-08 34.2 0.4 3.2e-08 33.3 0.4 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 OEU15599.1 - 1.9e-08 34.0 0.0 3.2e-07 30.0 0.1 2.5 1 1 1 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OEU15599.1 - 1.6e-05 24.9 0.2 0.0047 16.8 0.2 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OEU15599.1 - 2.5e-05 24.4 1.0 0.0022 18.1 0.5 3.6 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 OEU15599.1 - 0.00012 21.7 0.1 0.012 15.2 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 OEU15599.1 - 0.0069 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 MeaB PF03308.16 OEU15599.1 - 0.011 14.8 0.3 0.84 8.6 0.1 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AF-4 PF05110.13 OEU15599.1 - 0.019 13.1 5.3 0.026 12.6 5.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_5 PF07728.14 OEU15599.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AlaDh_PNT_C PF01262.21 OEU15599.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SDP_N PF12278.8 OEU15599.1 - 2.8 8.1 6.4 0.88 9.7 2.6 2.0 2 0 0 2 2 2 0 Sex determination protein N terminal PTPS PF01242.19 OEU15600.1 - 1.7e-16 60.3 0.0 1.8e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase WD40 PF00400.32 OEU15601.1 - 2.9e-31 107.0 26.2 2e-06 28.4 0.0 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat Utp12 PF04003.12 OEU15601.1 - 2.1e-15 56.9 1.4 2.1e-15 56.9 1.4 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family Nup160 PF11715.8 OEU15601.1 - 0.0021 16.8 10.9 0.015 14.0 0.0 4.5 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Hira PF07569.11 OEU15601.1 - 0.14 11.9 2.9 12 5.6 0.1 3.5 2 1 1 3 3 3 0 TUP1-like enhancer of split TMEM191C PF15194.6 OEU15601.1 - 1.8 8.7 4.5 1.6e+02 2.5 3.7 3.4 3 1 0 3 3 3 0 TMEM191C family PRKCSH PF07915.13 OEU15602.1 - 3.8e-06 27.8 10.4 2.9e-05 25.0 6.3 2.3 1 1 1 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OEU15602.1 - 6.7e-06 25.9 2.0 4.2e-05 23.3 2.0 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF1522 PF07482.11 OEU15602.1 - 0.076 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) DUF1221 PF06760.11 OEU15602.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Laps PF10169.9 OEU15603.1 - 0.014 15.9 0.8 0.034 14.7 0.8 1.6 1 0 0 1 1 1 0 Learning-associated protein Calcipressin PF04847.12 OEU15603.1 - 0.43 10.3 2.1 0.57 9.9 1.1 1.8 2 0 0 2 2 2 0 Calcipressin SF-assemblin PF06705.11 OEU15604.1 - 0.00068 19.1 6.3 0.0012 18.2 6.3 1.4 1 0 0 1 1 1 1 SF-assemblin/beta giardin p31comet PF06581.12 OEU15605.1 - 0.0027 16.9 0.2 0.0039 16.4 0.2 1.2 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding DUF92 PF01940.16 OEU15605.1 - 1.7 8.0 9.6 1.6 8.1 8.7 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF92 Choline_transpo PF04515.12 OEU15606.1 - 8.3e-62 209.3 38.3 8.3e-62 209.3 38.3 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter SNF2_N PF00176.23 OEU15607.1 - 1.1e-46 159.1 0.4 1.7e-45 155.3 0.4 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU15607.1 - 2.9e-16 59.8 0.0 1.2e-13 51.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 OEU15607.1 - 0.00012 21.8 8.9 0.00012 21.8 8.9 3.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.6 OEU15607.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 2.5 2 0 0 2 2 1 1 zinc-finger of a C2HC-type DEAD PF00270.29 OEU15607.1 - 0.002 17.9 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_4 PF14570.6 OEU15607.1 - 0.006 16.4 16.8 0.097 12.5 9.5 3.1 2 1 0 2 2 2 2 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 OEU15607.1 - 0.011 15.7 1.8 0.011 15.7 1.8 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zinc_ribbon_4 PF13717.6 OEU15607.1 - 0.017 15.0 3.3 1.2 9.1 0.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 OEU15607.1 - 0.1 12.4 2.7 5.1 7.0 0.6 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 OEU15607.1 - 0.12 12.8 2.0 0.93 10.0 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger double domain TRAF6_Z2 PF18048.1 OEU15607.1 - 8.1 6.6 8.0 0.82 9.8 0.4 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Pho88 PF10032.9 OEU15608.1 - 3.3e-29 101.5 5.2 9.6e-29 99.9 5.2 1.7 1 1 0 1 1 1 1 Phosphate transport (Pho88) TFIIA PF03153.13 OEU15608.1 - 0.00048 20.2 32.5 0.00083 19.5 13.4 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OEU15608.1 - 0.0032 15.8 9.0 0.0032 15.8 9.0 2.1 2 0 0 2 2 2 1 Nop14-like family BUD22 PF09073.10 OEU15608.1 - 0.0057 16.0 40.4 0.0063 15.9 18.9 2.1 2 0 0 2 2 2 2 BUD22 CDC45 PF02724.14 OEU15608.1 - 0.024 13.0 31.1 0.0061 14.9 1.8 2.1 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.7 OEU15608.1 - 0.081 12.7 18.0 0.42 10.4 6.1 2.6 3 0 0 3 3 3 0 SpoIIIAH-like protein Spore_coat_CotO PF14153.6 OEU15608.1 - 0.15 12.0 13.9 1.4 8.8 1.9 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Astro_capsid_p PF12226.8 OEU15608.1 - 0.22 10.6 37.2 0.18 10.9 16.8 2.3 2 0 0 2 2 2 0 Turkey astrovirus capsid protein CPSF100_C PF13299.6 OEU15608.1 - 3.5 7.8 13.7 9.1 6.4 3.9 2.8 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Endomucin PF07010.12 OEU15609.1 - 0.46 10.4 0.0 0.46 10.4 0.0 3.0 3 0 0 3 3 3 0 Endomucin Ndc80_HEC PF03801.13 OEU15610.1 - 4.3e-40 136.8 0.0 9.3e-40 135.7 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family zf-C4H2 PF10146.9 OEU15610.1 - 0.0024 18.2 7.3 0.0024 18.2 7.3 2.6 2 0 0 2 2 2 1 Zinc finger-containing protein Spc7 PF08317.11 OEU15610.1 - 0.1 11.4 37.3 0.0082 15.1 18.3 3.0 3 1 1 4 4 4 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OEU15610.1 - 0.14 12.2 7.1 1.5 8.9 4.8 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_Tnp_IS240 PF13610.6 OEU15610.1 - 0.17 12.1 4.5 1.8 8.8 1.0 2.7 2 1 0 2 2 2 0 DDE domain Fez1 PF06818.15 OEU15610.1 - 0.33 11.4 26.8 1.8 9.0 9.7 2.2 2 0 0 2 2 2 0 Fez1 BLOC1_2 PF10046.9 OEU15610.1 - 0.53 10.6 25.0 0.25 11.7 3.0 5.5 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 OEU15610.1 - 0.61 10.5 12.2 2.7 8.4 0.3 4.0 2 2 2 4 4 4 0 Uncharacterized KorC regulated protein A NPV_P10 PF05531.12 OEU15610.1 - 0.61 10.6 13.1 1.1 9.7 0.9 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3829 PF12889.7 OEU15610.1 - 0.65 9.4 14.8 0.015 14.8 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF3496 PF12001.8 OEU15610.1 - 0.79 10.1 8.9 1.5 9.2 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) MAD PF05557.13 OEU15610.1 - 0.85 7.9 31.4 0.058 11.7 13.3 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein Cauli_AT PF03233.13 OEU15610.1 - 3.4 7.6 13.0 6.1 6.7 6.7 2.6 2 1 0 2 2 2 0 Aphid transmission protein Noelin-1 PF12308.8 OEU15610.1 - 4.6 7.3 7.3 5.9 6.9 2.3 3.3 3 1 0 3 3 3 0 Neurogenesis glycoprotein AATF-Che1 PF13339.6 OEU15610.1 - 6.1 7.5 14.2 0.42 11.3 5.4 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF948 PF06103.11 OEU15610.1 - 7.1 7.0 6.3 13 6.1 2.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PI-PLC-X PF00388.19 OEU15611.1 - 0.00096 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain LpoB PF13036.6 OEU15611.1 - 0.23 11.4 0.3 0.36 10.8 0.3 1.2 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Guanylate_cyc PF00211.20 OEU15612.1 - 7.3e-46 156.1 0.1 8.2e-46 155.9 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF829 PF05705.14 OEU15616.1 - 4.4e-33 115.2 0.8 2.9e-22 79.7 0.4 2.6 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) YejG PF13989.6 OEU15616.1 - 0.044 14.2 0.1 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 YejG-like protein CAP_N PF01213.19 OEU15616.1 - 0.17 11.4 1.8 0.3 10.5 1.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Lactamase_B PF00753.27 OEU15617.1 - 0.00022 21.3 3.3 0.00058 19.9 1.5 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Serine_protease PF18405.1 OEU15617.1 - 0.038 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease TPP_enzyme_M PF00205.22 OEU15617.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Flavoprotein PF02441.19 OEU15618.1 - 9.5e-40 135.9 0.0 7.5e-37 126.5 0.0 2.0 1 1 1 2 2 2 2 Flavoprotein RPA_C PF08784.11 OEU15619.1 - 8.2e-13 48.9 4.2 8.2e-13 48.9 4.2 2.4 2 2 1 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OEU15619.1 - 5.4e-05 23.1 1.7 0.00012 21.9 1.7 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 OEU15619.1 - 0.031 14.1 0.4 0.053 13.4 0.4 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 DUF4539 PF15072.6 OEU15619.1 - 0.033 14.2 0.2 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) M_domain PF12938.7 OEU15619.1 - 1.8 8.3 10.6 0.14 11.9 4.9 1.9 2 0 0 2 2 2 0 M domain of GW182 TB2_DP1_HVA22 PF03134.19 OEU15620.1 - 2.7e-28 97.7 6.1 2.7e-28 97.7 6.1 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Rhomboid PF01694.22 OEU15621.1 - 4.7e-19 68.9 15.2 4.7e-19 68.9 15.2 1.5 2 0 0 2 2 2 1 Rhomboid family ER_lumen_recept PF00810.18 OEU15622.1 - 6.8e-36 124.3 2.7 1.2e-35 123.5 2.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF4345 PF14248.6 OEU15622.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4345) PQ-loop PF04193.14 OEU15622.1 - 0.81 9.5 7.7 0.85 9.4 0.1 3.3 3 0 0 3 3 3 0 PQ loop repeat Peptidase_M16_M PF16187.5 OEU15623.1 - 1.2e-48 165.9 0.0 6.9e-48 163.4 0.0 2.3 1 1 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OEU15623.1 - 9.3e-35 119.8 0.1 1.7e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU15623.1 - 6.1e-24 85.0 0.0 5.3e-14 52.6 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF3306 PF11748.8 OEU15623.1 - 0.13 13.1 0.1 1 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Vps51 PF08700.11 OEU15624.1 - 3.3e-08 33.5 1.1 1.9e-07 31.1 1.1 2.4 1 0 0 1 1 1 1 Vps51/Vps67 EF-hand_1 PF00036.32 OEU15624.1 - 0.039 13.5 0.6 0.2 11.3 0.1 2.6 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 OEU15624.1 - 0.061 13.3 0.3 2.9 8.1 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain DUF3824 PF12868.7 OEU15624.1 - 0.73 10.5 8.0 0.64 10.7 6.3 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) T7SS_ESX_EspC PF10824.8 OEU15624.1 - 1.8 9.1 5.8 7.6 7.1 0.6 3.5 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm SMC_N PF02463.19 OEU15625.1 - 6.2e-05 22.5 0.2 0.0057 16.1 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU15625.1 - 0.0003 21.1 0.2 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OEU15625.1 - 0.0083 16.6 1.4 0.078 13.5 0.0 3.1 3 1 0 3 3 3 1 ABC transporter NACHT PF05729.12 OEU15625.1 - 0.016 15.1 0.0 0.056 13.4 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 OEU15625.1 - 0.044 13.8 0.2 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU15625.1 - 0.1 13.0 0.0 0.1 13.0 0.0 2.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 OEU15625.1 - 0.1 12.3 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OEU15625.1 - 0.12 12.3 0.2 0.32 10.9 0.2 1.8 1 0 0 1 1 1 0 NTPase AAA PF00004.29 OEU15625.1 - 0.13 12.7 1.3 38 4.7 0.1 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OEU15625.1 - 1.7 9.1 4.3 9.4 6.7 4.3 2.2 1 1 0 1 1 1 0 AAA domain NDK PF00334.19 OEU15628.1 - 1.2e-53 180.8 0.0 1.4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase LRR_6 PF13516.6 OEU15629.1 - 5.4e-26 88.4 21.8 0.00063 19.6 0.3 10.0 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 OEU15629.1 - 5.9e-05 23.4 21.8 0.77 10.3 0.3 7.2 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU15629.1 - 0.00047 19.9 18.7 0.34 10.7 0.6 7.0 5 3 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 OEU15629.1 - 0.0098 16.3 11.5 1.7e+02 3.4 0.0 8.1 8 0 0 8 8 8 0 Leucine Rich Repeat UDPGP PF01704.18 OEU15630.1 - 1.2e-55 188.8 0.0 1.5e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 OEU15630.1 - 4e-05 24.0 0.0 8.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Complex1_LYR PF05347.15 OEU15631.1 - 5.4e-11 42.4 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 OEU15631.1 - 0.00082 19.9 0.0 0.00091 19.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 OEU15631.1 - 0.039 14.7 0.1 0.044 14.5 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like NARP1 PF12569.8 OEU15632.1 - 5.8e-135 451.1 15.2 5.3e-134 447.9 10.1 2.9 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 OEU15632.1 - 4.6e-11 41.9 15.3 7.8e-05 22.5 0.1 7.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU15632.1 - 9.3e-11 42.1 5.9 0.0046 17.4 0.3 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 OEU15632.1 - 2.1e-08 34.3 5.8 0.29 12.1 0.0 6.8 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15632.1 - 8.8e-07 28.5 17.2 0.00083 19.1 0.2 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15632.1 - 2.7e-06 27.1 5.9 0.00047 20.2 0.1 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU15632.1 - 3.1e-05 24.2 8.4 0.28 11.5 0.0 6.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU15632.1 - 4.5e-05 23.0 0.2 4.5e-05 23.0 0.2 5.4 6 0 0 6 6 6 1 TPR repeat TPR_9 PF13371.6 OEU15632.1 - 7e-05 22.9 0.3 3 8.1 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU15632.1 - 7.2e-05 22.8 12.6 0.48 10.5 0.4 5.2 5 0 0 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 OEU15632.1 - 8.4e-05 23.1 6.4 6.8 7.4 0.1 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU15632.1 - 0.00016 21.9 0.4 0.9 10.1 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU15632.1 - 0.00016 22.1 2.7 5.9 7.7 0.2 5.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU15632.1 - 0.0007 19.4 0.1 0.0076 16.2 0.1 2.9 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU15632.1 - 0.0013 18.9 8.4 0.066 13.4 1.1 5.1 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 OEU15632.1 - 0.05 13.6 3.6 0.13 12.3 0.3 2.8 2 1 0 2 2 2 0 Putative TPR-like repeat TPR_MalT PF17874.1 OEU15632.1 - 0.081 12.3 0.4 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 MalT-like TPR region YfiO PF13525.6 OEU15632.1 - 0.082 12.6 5.9 0.92 9.2 0.2 3.1 3 0 0 3 3 2 0 Outer membrane lipoprotein AAA_18 PF13238.6 OEU15633.1 - 2.6e-28 99.2 0.1 4e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OEU15633.1 - 5.8e-11 43.0 0.3 1.5e-10 41.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU15633.1 - 9.7e-09 35.5 0.0 6.3e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 OEU15633.1 - 5.6e-06 26.5 0.3 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 OEU15633.1 - 2.6e-05 24.5 0.1 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OEU15633.1 - 3.1e-05 24.4 0.0 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 OEU15633.1 - 0.00018 21.4 1.8 0.018 14.9 0.2 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase Zeta_toxin PF06414.12 OEU15633.1 - 0.00027 20.3 0.1 0.00092 18.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 OEU15633.1 - 0.003 18.0 0.2 0.0074 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OEU15633.1 - 0.0041 17.0 0.1 0.065 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OEU15633.1 - 0.008 15.9 0.2 0.016 15.0 0.2 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU15633.1 - 0.0089 16.3 0.5 0.024 14.9 0.1 1.7 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 OEU15633.1 - 0.014 15.5 1.5 0.11 12.6 1.5 2.1 1 1 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.15 OEU15633.1 - 0.019 14.9 0.2 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 OEU15633.1 - 0.022 14.0 0.5 0.079 12.2 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OEU15633.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OEU15633.1 - 0.039 14.3 0.6 0.039 14.3 0.6 2.0 1 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 OEU15633.1 - 0.059 13.6 0.1 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 OEU15633.1 - 0.14 11.9 1.8 0.32 10.7 0.7 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OEU15633.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ANTH PF07651.16 OEU15634.1 - 4.2e-09 35.8 0.0 6.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OEU15634.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TFIIA PF03153.13 OEU15634.1 - 0.0029 17.7 8.0 0.0034 17.5 8.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 OEU15634.1 - 0.3 11.7 6.5 13 6.4 4.4 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTS_2-RNA PF01885.16 OEU15635.1 - 4.5e-51 173.5 0.0 5.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family eIF-1a PF01176.19 OEU15636.1 - 3.5e-11 42.8 0.0 7.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Radial_spoke PF04712.12 OEU15636.1 - 0.31 9.9 11.9 0.054 12.4 8.0 1.5 1 1 0 1 1 1 0 Radial spokehead-like protein Presenilin PF01080.17 OEU15636.1 - 0.53 9.0 6.1 0.71 8.6 6.1 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 OEU15636.1 - 0.87 8.3 7.2 1.3 7.8 7.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 OEU15636.1 - 4.5 7.7 6.1 1.7 9.1 1.3 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 PhoQ_Sensor PF08918.10 OEU15636.1 - 5.7 6.7 10.1 12 5.7 2.4 2.2 2 0 0 2 2 2 0 PhoQ Sensor PepSY_TM_like_2 PF16357.5 OEU15637.1 - 0.14 12.1 0.2 0.14 12.1 0.2 2.6 3 0 0 3 3 3 0 Putative PepSY_TM-like WTF PF03303.13 OEU15638.1 - 4.7 6.9 5.1 8.1 6.1 5.1 1.4 1 0 0 1 1 1 0 WTF protein Prefoldin PF02996.17 OEU15640.1 - 1.6e-10 40.9 2.1 2.1e-10 40.6 1.6 1.5 1 1 0 1 1 1 1 Prefoldin subunit DUF2207 PF09972.9 OEU15641.1 - 0.0073 15.1 0.1 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Pneumo_ncap PF03246.13 OEU15641.1 - 0.061 12.1 0.6 0.11 11.3 0.6 1.3 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein SNARE PF05739.19 OEU15641.1 - 3.4 7.7 4.3 6.6 6.8 4.3 1.4 1 0 0 1 1 1 0 SNARE domain Rad9 PF04139.13 OEU15642.1 - 1e-23 84.1 0.2 1.4e-23 83.6 0.2 1.2 1 0 0 1 1 1 1 Rad9 IL1_propep PF02394.16 OEU15642.1 - 0.014 16.3 0.7 0.036 15.0 0.7 1.7 1 1 0 1 1 1 0 Interleukin-1 propeptide Branch PF02485.21 OEU15644.1 - 4.3e-08 33.0 0.3 5.1e-08 32.7 0.3 1.0 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ricin_B_lectin PF00652.22 OEU15645.1 - 0.0097 16.2 0.2 0.053 13.8 0.0 2.4 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain zf-C2HE PF16278.5 OEU15645.1 - 0.048 14.1 0.8 0.067 13.6 0.0 1.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LRR_6 PF13516.6 OEU15646.1 - 1.5e-07 30.9 1.3 0.1 12.7 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 OEU15646.1 - 0.022 15.2 0.2 63 4.7 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 OEU15646.1 - 0.023 15.1 6.9 0.21 12.1 0.2 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 OEU15646.1 - 0.026 15.2 1.7 2.7 8.8 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat TrmE_N PF10396.9 OEU15646.1 - 0.044 14.1 0.0 0.075 13.4 0.0 1.4 1 1 0 1 1 1 0 GTP-binding protein TrmE N-terminus LRR_8 PF13855.6 OEU15646.1 - 0.72 9.7 4.7 2.7 7.8 0.1 3.6 4 1 0 4 4 4 0 Leucine rich repeat Pro_isomerase PF00160.21 OEU15647.1 - 9e-44 149.5 0.1 1e-43 149.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PapD-like PF14874.6 OEU15647.1 - 0.05 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like CLPTM1 PF05602.12 OEU15648.1 - 1.7e-61 208.6 0.6 2e-61 208.3 0.6 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OEU15648.1 - 2.7e-05 23.9 1.0 0.093 12.5 0.0 2.8 2 0 0 2 2 2 2 PQ loop repeat APP_Cu_bd PF12924.7 OEU15649.1 - 0.07 13.9 0.1 0.14 13.0 0.1 1.5 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD GARS_A PF01071.19 OEU15650.1 - 1.5e-76 256.6 0.0 2.4e-76 255.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 OEU15650.1 - 2.7e-44 151.1 0.0 4.6e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.22 OEU15650.1 - 3.1e-33 115.1 0.0 7.1e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 OEU15650.1 - 9.1e-24 83.6 0.2 2.7e-23 82.1 0.2 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OEU15650.1 - 6.6e-15 55.5 1.0 2.3e-14 53.8 1.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GARS_N PF02844.15 OEU15650.1 - 3.5e-09 37.3 0.1 1.4e-08 35.4 0.1 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain ATP-grasp_3 PF02655.14 OEU15650.1 - 0.00017 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OEU15650.1 - 0.002 17.6 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Sulfotransfer_1 PF00685.27 OEU15651.1 - 6.8e-07 29.0 0.3 1.3e-06 28.1 0.3 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU15651.1 - 0.063 13.7 2.9 11 6.3 0.0 2.8 2 1 0 3 3 3 0 Sulfotransferase family AMP-binding PF00501.28 OEU15652.1 - 3.6e-83 279.5 0.0 4.7e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OEU15652.1 - 1.8e-18 67.3 0.1 3.6e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OEU15652.1 - 3.2e-15 55.8 1.6 3.2e-15 55.8 1.6 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Chalcone_3 PF16036.5 OEU15653.1 - 2e-13 50.8 0.0 2.6e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone_2 PF16035.5 OEU15653.1 - 4.5e-06 26.6 0.0 0.012 15.4 0.0 2.1 1 1 1 2 2 2 2 Chalcone isomerase like Bystin PF05291.11 OEU15654.1 - 5e-128 426.5 1.1 5.8e-128 426.2 1.1 1.0 1 0 0 1 1 1 1 Bystin Ribosomal_S2 PF00318.20 OEU15655.1 - 2.5e-25 89.0 0.0 1.2e-11 44.2 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OEU15655.1 - 1.1 10.6 7.5 2.4 9.6 7.5 1.6 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Histone PF00125.24 OEU15656.1 - 1.5e-18 67.4 0.0 2.1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OEU15656.1 - 2.3e-13 49.6 0.7 4.2e-13 48.8 0.7 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OEU15656.1 - 0.00047 20.4 0.0 0.00063 20.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OEU15657.1 - 2.4e-18 66.4 0.0 4e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OEU15657.1 - 2.2e-05 24.6 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU15657.1 - 0.083 13.3 0.0 0.083 13.3 0.0 5.0 4 1 0 4 4 4 0 Core histone H2A/H2B/H3/H4 TPR_12 PF13424.6 OEU15659.1 - 0.0075 16.5 11.6 0.31 11.4 0.2 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15659.1 - 0.039 14.2 11.7 4.1 7.9 0.0 5.8 4 1 0 4 4 4 0 Tetratricopeptide repeat HD_6 PF18019.1 OEU15659.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.2 3 0 0 3 3 3 0 HD domain NPV_P10 PF05531.12 OEU15659.1 - 1.7 9.2 9.4 0.14 12.6 2.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_7 PF13176.6 OEU15659.1 - 2.8 8.2 8.9 14 6.0 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat NTP_transf_2 PF01909.23 OEU15660.1 - 1e-07 32.2 0.0 3e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OEU15660.1 - 2.1e-07 31.1 0.6 1.5e-06 28.3 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase Fes1 PF08609.10 OEU15661.1 - 0.045 14.6 1.9 0.12 13.3 0.4 2.5 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 PhyH PF05721.13 OEU15662.1 - 3.2e-18 66.8 0.0 6e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CPL PF08144.11 OEU15663.1 - 2.7e-16 60.2 5.6 2.3e-15 57.2 0.1 4.1 4 2 1 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 OEU15663.1 - 0.0011 18.6 0.0 3 7.7 0.0 3.6 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat TOPRIM_C PF16898.5 OEU15663.1 - 0.12 12.7 1.5 0.33 11.2 0.1 2.3 1 1 0 2 2 2 0 C-terminal associated domain of TOPRIM OmpH PF03938.14 OEU15663.1 - 0.53 10.6 9.6 0.5 10.7 7.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SET PF00856.28 OEU15665.1 - 3.7e-05 24.2 0.1 5.4e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 SET domain GlcNAc PF11397.8 OEU15666.1 - 4.1e-58 197.5 0.9 2.6e-45 155.4 0.3 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 OEU15666.1 - 0.0078 16.0 0.1 0.093 12.5 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 GST_N_3 PF13417.6 OEU15667.1 - 2.6e-05 24.6 0.0 4.3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU15667.1 - 0.0018 18.6 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU15667.1 - 0.0029 17.9 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PKI PF02827.16 OEU15667.1 - 0.33 11.2 1.9 0.7 10.1 1.9 1.6 1 1 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF2358 PF10184.9 OEU15668.1 - 6.6e-06 26.4 0.3 0.012 15.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2358) UBA2_C PF16195.5 OEU15668.1 - 0.22 12.3 5.8 0.71 10.6 0.5 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF2714 PF10896.8 OEU15668.1 - 1 9.4 4.0 1.6 8.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) CDC73_C PF05179.14 OEU15669.1 - 2.2e-28 98.9 0.1 2.3e-28 98.9 0.1 1.0 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Cpn60_TCP1 PF00118.24 OEU15670.1 - 5.2e-144 480.5 2.4 6e-144 480.3 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_3 PF13456.6 OEU15671.1 - 7.5e-27 93.6 0.2 2.1e-12 46.9 0.1 2.9 2 1 0 2 2 2 2 Reverse transcriptase-like BATS PF06968.13 OEU15672.1 - 5.7e-18 64.8 0.0 2e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OEU15672.1 - 2.7e-13 50.6 0.1 4.5e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M24 PF00557.24 OEU15672.1 - 0.031 14.0 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 Ribosomal_S24e PF01282.19 OEU15673.1 - 8.7e-32 108.9 0.3 1.6e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e Lipase_GDSL_2 PF13472.6 OEU15674.1 - 0.03 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ArfGap PF01412.18 OEU15675.1 - 3.1e-25 88.5 2.2 2.1e-24 85.8 2.2 2.0 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1077 PF06417.12 OEU15677.1 - 4 7.5 8.5 7.8 6.5 8.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1077) NIF PF03031.18 OEU15678.1 - 2.5e-24 85.8 0.0 5.2e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 OEU15678.1 - 0.00042 20.0 1.4 0.00065 19.4 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF2627 PF11118.8 OEU15680.1 - 0.001 19.6 0.2 0.0024 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2627) RIFIN PF02009.16 OEU15680.1 - 0.051 13.5 0.2 0.075 12.9 0.2 1.2 1 0 0 1 1 1 0 Rifin Saf_2TM PF18303.1 OEU15680.1 - 0.066 12.8 0.4 0.12 11.9 0.1 1.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Pox_A14 PF05767.12 OEU15680.1 - 0.093 12.9 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Peptidase_M56 PF05569.11 OEU15680.1 - 0.2 10.8 0.0 0.51 9.5 0.0 1.6 2 0 0 2 2 2 0 BlaR1 peptidase M56 ATP-synt_E PF05680.12 OEU15680.1 - 0.91 9.9 3.9 0.75 10.2 0.7 2.2 2 0 0 2 2 2 0 ATP synthase E chain CDC45 PF02724.14 OEU15680.1 - 1.2 7.3 14.2 1.7 6.9 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OEU15680.1 - 3.1 5.9 24.3 4 5.5 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 OEU15680.1 - 3.3 7.3 15.5 5.1 6.7 15.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 OEU15680.1 - 3.8 6.8 25.2 5.1 6.4 25.2 1.1 1 0 0 1 1 1 0 SDA1 Lipid_DES PF08557.10 OEU15681.1 - 1.3e-13 50.1 0.0 2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 OEU15681.1 - 1.3e-07 31.7 3.9 1.3e-07 31.7 3.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DNA_gyraseB PF00204.25 OEU15682.1 - 1.5e-48 164.6 0.0 2.6e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 OEU15682.1 - 1.2e-27 95.8 0.1 2.4e-27 94.9 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 OEU15682.1 - 7.8e-19 67.8 0.0 2e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 OEU15682.1 - 1.3e-17 64.3 0.2 3.5e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OEU15682.1 - 0.0002 21.2 0.0 0.00071 19.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDPD PF03009.17 OEU15682.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Arm PF00514.23 OEU15683.1 - 2.8e-13 49.4 5.8 0.00023 21.1 0.0 6.9 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 OEU15683.1 - 7.9e-05 22.6 7.1 0.22 11.6 0.1 5.6 3 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 OEU15683.1 - 0.00072 20.0 0.7 7 7.3 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 OEU15683.1 - 0.042 14.1 0.1 7.9 7.0 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat UNC45-central PF11701.8 OEU15683.1 - 0.13 12.2 1.8 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Methyltransf_21 PF05050.12 OEU15685.1 - 1.6e-12 47.8 0.0 3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 OEU15685.1 - 0.0031 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain IF-2B PF01008.17 OEU15686.1 - 3e-47 161.2 0.1 3.4e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ala_racemase_N PF01168.20 OEU15687.1 - 1.4e-33 116.4 1.3 6.6e-33 114.2 1.3 2.1 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 OEU15687.1 - 3.2e-31 107.7 0.0 6.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Cation_efflux PF01545.21 OEU15688.1 - 2.8e-06 27.2 16.8 4.7e-06 26.5 16.8 1.3 1 0 0 1 1 1 1 Cation efflux family DUF5408 PF17402.2 OEU15688.1 - 0.016 15.1 1.8 3.4 7.6 0.7 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF1077 PF06417.12 OEU15688.1 - 0.091 12.8 1.7 0.11 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) Tmemb_14 PF03647.13 OEU15688.1 - 0.17 12.7 8.2 4.4 8.1 4.9 2.6 1 1 0 2 2 2 0 Transmembrane proteins 14C Fig1 PF12351.8 OEU15688.1 - 0.19 11.6 10.2 0.62 10.0 3.2 2.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 FA_desaturase PF00487.24 OEU15690.1 - 0.072 12.9 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Apq12 PF12716.7 OEU15690.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Calc_CGRP_IAPP PF00214.19 OEU15691.1 - 0.16 12.4 1.0 0.74 10.2 1.0 2.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family RunxI PF08504.11 OEU15691.1 - 0.19 12.5 5.2 0.35 11.6 0.1 3.6 3 0 0 3 3 3 0 Runx inhibition domain PCI PF01399.27 OEU15692.1 - 2.7e-11 43.9 0.1 7.9e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 OEU15692.1 - 3.7e-08 32.9 0.4 3.7e-08 32.9 0.4 2.2 3 0 0 3 3 3 1 eIF3 subunit M, C-terminal helix GM_CSF PF01109.17 OEU15692.1 - 0.019 15.2 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor NCD1 PF04904.13 OEU15692.1 - 0.08 13.0 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Pyr_redox_2 PF07992.14 OEU15693.1 - 5.2e-19 68.6 0.0 6.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU15693.1 - 2.3e-05 24.9 0.0 4.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU15693.1 - 0.06 12.5 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NIL PF09383.10 OEU15693.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NIL domain NAD_binding_8 PF13450.6 OEU15693.1 - 0.11 12.8 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU15693.1 - 0.13 11.8 0.6 0.22 11.1 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase EccE PF11203.8 OEU15693.1 - 0.5 10.7 2.0 2.4 8.5 0.0 2.8 3 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE HA PF03457.14 OEU15694.1 - 2.6e-10 40.5 2.1 5.6e-10 39.4 2.1 1.7 1 1 0 1 1 1 1 Helicase associated domain CNDH2_M PF16869.5 OEU15694.1 - 0.48 11.1 8.9 0.66 10.7 8.7 1.3 1 1 0 1 1 1 0 PF16858 AAA_18 PF13238.6 OEU15695.1 - 2.7e-06 27.9 0.2 4.9e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU15695.1 - 2.8e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OEU15695.1 - 0.00013 22.4 1.3 0.0029 18.0 1.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU15695.1 - 0.00013 22.4 0.0 0.00024 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 OEU15695.1 - 0.00017 21.0 0.2 0.00026 20.3 0.2 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OEU15695.1 - 0.00021 21.6 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OEU15695.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 OEU15695.1 - 0.0075 16.6 0.0 0.017 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU15695.1 - 0.0079 15.5 0.0 0.02 14.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 OEU15695.1 - 0.0093 16.4 0.2 0.039 14.4 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 OEU15695.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 OEU15695.1 - 0.014 15.3 0.1 0.021 14.7 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OEU15695.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 OEU15695.1 - 0.047 13.4 0.3 0.087 12.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OEU15695.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 OEU15695.1 - 0.081 12.6 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OEU15695.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 OEU15695.1 - 0.14 11.9 3.0 0.5 10.1 3.0 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OEU15695.1 - 0.18 11.4 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 OEU15695.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain GP24_25 PF17388.2 OEU15696.1 - 0.038 14.0 1.9 0.082 12.9 1.9 1.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 DUF3246 PF11596.8 OEU15696.1 - 0.51 9.7 9.9 0.015 14.7 3.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) KIAA1430 PF13879.6 OEU15696.1 - 0.78 10.5 3.9 1.9 9.3 0.3 2.7 2 1 0 2 2 2 0 KIAA1430 homologue TFIIE-A_C PF11521.8 OEU15696.1 - 9.9 6.5 11.7 1.3 9.3 1.9 3.3 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha DUF1118 PF06549.12 OEU15697.1 - 0.00015 22.1 4.7 0.00015 22.1 4.7 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1118) PQ-loop PF04193.14 OEU15698.1 - 6.4e-07 29.0 2.9 0.00049 19.8 0.0 3.2 3 0 0 3 3 3 2 PQ loop repeat YrhK PF14145.6 OEU15698.1 - 0.042 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 YrhK-like protein FUSC-like PF12805.7 OEU15698.1 - 0.076 12.1 0.2 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS MNSV_P7B PF06692.11 OEU15698.1 - 0.12 12.4 0.4 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Glutaredoxin PF00462.24 OEU15699.1 - 1.7e-09 37.7 0.0 5.1e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Glutaredoxin Methyltransf_4 PF02390.17 OEU15700.1 - 3.1e-05 23.5 0.4 0.63 9.5 0.0 3.5 4 0 0 4 4 4 2 Putative methyltransferase CCB2_CCB4 PF11152.8 OEU15700.1 - 0.054 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 DUF406 PF04175.12 OEU15700.1 - 2.2 8.8 7.4 0.53 10.8 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF406) IMS PF00817.20 OEU15701.1 - 2e-38 131.7 0.0 4.1e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 OEU15701.1 - 1.8e-10 41.1 0.0 9.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 OEU15701.1 - 1.1e-07 32.5 0.0 6.5e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.7 OEU15701.1 - 9.2e-06 25.5 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 OEU15701.1 - 1.3e-05 25.5 0.0 0.00011 22.5 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 OEU15701.1 - 1.8e-05 24.8 0.4 0.00012 22.2 0.1 2.6 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 OEU15701.1 - 0.00052 20.2 0.1 0.0029 17.9 0.0 2.4 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain SRR1 PF07985.12 OEU15702.1 - 2.6e-09 37.0 0.0 7.5e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 SRR1 Dishevelled PF02377.15 OEU15702.1 - 0.33 11.4 18.1 0.064 13.7 3.7 3.3 3 0 0 3 3 3 0 Dishevelled specific domain Spt5_N PF11942.8 OEU15702.1 - 4.4 8.3 10.5 3.2 8.8 3.1 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Isochorismatase PF00857.20 OEU15703.1 - 1.6e-24 87.0 0.2 1.9e-24 86.8 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family Reprolysin_3 PF13582.6 OEU15704.1 - 8.7e-05 23.0 7.3 0.00015 22.3 0.6 3.0 2 1 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OEU15704.1 - 0.0059 16.8 6.3 0.014 15.5 6.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OEU15704.1 - 0.045 13.6 0.3 0.083 12.7 0.3 1.6 1 1 0 1 1 1 0 Matrixin Apis_Csd PF11671.8 OEU15704.1 - 1.2 9.1 8.6 1.1 9.3 2.3 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein Secretin_N_2 PF07655.13 OEU15704.1 - 2.4 8.7 18.2 1.8 9.2 1.2 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Apc13p PF05839.11 OEU15705.1 - 4.2e-07 30.1 0.9 9.7e-07 28.9 0.9 1.6 1 1 0 1 1 1 1 Apc13p protein Herpes_pp85 PF04637.12 OEU15705.1 - 0.34 9.3 4.9 0.46 8.8 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Aldo_ket_red PF00248.21 OEU15706.1 - 1.9e-21 76.5 0.0 8.6e-21 74.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Ham1p_like PF01725.16 OEU15708.1 - 7.7e-56 189.0 0.0 9e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family PfkB PF00294.24 OEU15709.1 - 6.1e-47 160.4 3.0 9e-47 159.8 3.0 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OEU15709.1 - 7.3e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase SpoU_methylase PF00588.19 OEU15710.1 - 0.0048 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family Tub_N PF16322.5 OEU15710.1 - 0.65 10.4 15.4 1.5 9.2 5.6 2.5 2 0 0 2 2 2 0 Tubby N-terminal CDK5_activator PF03261.15 OEU15711.1 - 1.6 8.2 19.9 0.11 12.0 13.7 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.13 OEU15711.1 - 3.1 7.7 29.8 0.013 15.6 19.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 OEU15714.1 - 3.7e-09 36.3 0.0 5.5e-09 35.8 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 OEU15714.1 - 0.069 12.8 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Topoisom_bac PF01131.20 OEU15715.1 - 5.6e-95 318.8 1.5 4e-88 296.2 0.9 2.6 2 0 0 2 2 2 2 DNA topoisomerase HMG_box PF00505.19 OEU15715.1 - 8.5e-41 138.2 9.1 4.3e-14 52.7 0.3 3.7 3 0 0 3 3 3 3 HMG (high mobility group) box Toprim_C_rpt PF13368.6 OEU15715.1 - 3.4e-34 116.6 0.4 8.3e-12 44.9 0.0 5.0 4 1 0 4 4 4 4 Topoisomerase C-terminal repeat HMG_box_2 PF09011.10 OEU15715.1 - 5.1e-33 113.5 10.3 4.2e-12 46.5 0.2 3.8 3 0 0 3 3 3 3 HMG-box domain Toprim PF01751.22 OEU15715.1 - 2.6e-23 82.2 0.0 8.3e-23 80.6 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 OEU15715.1 - 0.0046 17.3 0.2 0.026 14.9 0.1 2.4 2 0 0 2 2 2 1 Toprim-like Toprim_4 PF13662.6 OEU15715.1 - 0.0056 17.1 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 OEU15715.1 - 0.054 13.9 0.0 0.26 11.7 0.0 2.2 1 0 0 1 1 1 0 Toprim domain DUF2380 PF09533.10 OEU15715.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) ROS_MUCR PF05443.11 OEU15716.1 - 0.072 13.1 0.0 0.088 12.9 0.0 1.4 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Shisa PF13908.6 OEU15716.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3439 PF11921.8 OEU15717.1 - 0.14 12.1 2.5 0.22 11.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF445 PF04286.12 OEU15718.1 - 1.7e-09 38.0 2.5 0.043 13.6 0.1 4.1 2 2 2 4 4 4 4 Protein of unknown function (DUF445) DNA_primase_S PF01896.19 OEU15718.1 - 0.21 11.6 3.4 3.3 7.7 3.4 2.2 1 1 0 1 1 1 0 DNA primase small subunit TMEM151 PF14857.6 OEU15720.1 - 9.3e-11 41.3 5.0 6.4e-05 22.1 0.5 2.2 2 0 0 2 2 2 2 TMEM151 family Trypsin_2 PF13365.6 OEU15721.1 - 3e-22 80.1 1.7 8.5e-22 78.7 0.7 2.3 2 1 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 OEU15721.1 - 1.1e-11 45.0 0.2 6.1e-11 42.6 0.2 2.0 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 OEU15721.1 - 2.9e-09 37.1 0.1 6e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU15721.1 - 0.00016 21.5 0.3 0.62 9.9 0.1 2.7 1 1 1 2 2 2 2 PDZ domain Peptidase_S29 PF02907.15 OEU15721.1 - 0.00092 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 OEU15721.1 - 0.00098 19.0 0.2 0.0023 17.8 0.2 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.24 OEU15721.1 - 0.0022 18.3 0.9 0.048 14.0 0.3 3.0 2 1 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 OEU15721.1 - 0.0092 14.7 0.9 0.021 13.5 0.2 1.7 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S7 PF00949.21 OEU15721.1 - 0.063 13.1 0.6 0.16 11.8 0.6 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 OEU15721.1 - 0.094 12.2 0.4 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Putative peptidase (DUF31) V-ATPase_H_C PF11698.8 OEU15722.1 - 2.6e-35 121.1 0.1 7e-35 119.7 0.0 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 OEU15722.1 - 1.6e-25 90.1 0.0 1.4e-24 87.0 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 OEU15722.1 - 7.1e-08 32.2 4.4 0.05 13.7 0.9 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OEU15722.1 - 0.77 10.2 2.5 16 6.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat PPR_2 PF13041.6 OEU15723.1 - 1.9e-10 40.8 0.9 3.2e-06 27.2 0.0 4.2 4 1 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 OEU15723.1 - 2.1e-10 40.5 0.0 4.7e-05 23.4 0.0 4.5 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 OEU15723.1 - 7.7e-06 25.8 1.3 0.019 15.2 0.0 4.9 6 0 0 6 6 6 1 PPR repeat ATP13 PF12921.7 OEU15723.1 - 0.0017 18.2 0.3 0.06 13.2 0.1 2.8 2 0 0 2 2 2 1 Mitochondrial ATPase expression DUF2247 PF10004.9 OEU15723.1 - 0.005 16.6 3.0 0.093 12.5 0.0 3.3 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2247) PPR_1 PF12854.7 OEU15723.1 - 0.057 13.1 0.0 34 4.3 0.0 3.4 3 0 0 3 3 3 0 PPR repeat PPR_long PF17177.4 OEU15723.1 - 0.1 11.9 0.2 3.8 6.8 0.1 2.5 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP zf-DNL PF05180.12 OEU15724.1 - 5e-26 90.4 0.6 5.3e-26 90.3 0.6 1.0 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 OEU15724.1 - 0.0054 16.6 0.4 0.15 12.0 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon domain CpXC PF14353.6 OEU15724.1 - 0.03 14.4 0.7 0.04 14.0 0.7 1.3 1 1 0 1 1 1 0 CpXC protein HypA PF01155.19 OEU15724.1 - 0.078 13.0 0.4 0.086 12.9 0.4 1.0 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 OEU15724.1 - 0.088 12.2 0.9 0.13 11.6 0.9 1.3 1 0 0 1 1 1 0 Transcription factor zinc-finger Peroxin-22 PF12827.7 OEU15724.1 - 0.09 12.7 0.0 0.095 12.6 0.0 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Zn_Tnp_IS1595 PF12760.7 OEU15724.1 - 0.15 12.1 1.3 0.54 10.3 0.0 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 OEU15724.1 - 0.17 11.6 3.4 2.1 8.2 0.1 2.3 2 1 0 2 2 2 0 A2L zinc ribbon domain NAD_binding_10 PF13460.6 OEU15725.1 - 5.3e-36 124.2 0.3 7.3e-36 123.8 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU15725.1 - 7.4e-07 29.0 0.9 3.2e-06 26.9 0.9 1.9 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OEU15725.1 - 1.9e-06 27.1 0.3 2.7e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OEU15725.1 - 4.1e-06 26.4 0.8 6.9e-06 25.7 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OEU15725.1 - 1.8e-05 24.3 0.1 8e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OEU15725.1 - 0.0023 18.2 0.2 0.0049 17.1 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.12 OEU15725.1 - 0.0086 15.3 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 OEU15725.1 - 0.0099 15.4 0.4 0.017 14.7 0.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amnionless PF14828.6 OEU15725.1 - 0.073 11.9 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Amnionless LSM PF01423.22 OEU15726.1 - 1.9e-15 56.3 0.5 2.4e-15 56.0 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OEU15726.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.5 1 1 0 1 1 1 1 Hfq protein CopK PF11525.8 OEU15726.1 - 0.084 12.5 0.3 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Copper resistance protein K EMC3_TMCO1 PF01956.16 OEU15727.1 - 8.2e-05 22.4 1.6 0.01 15.6 0.3 3.0 1 1 1 2 2 2 2 Integral membrane protein EMC3/TMCO1-like Polysacc_synt PF01943.17 OEU15727.1 - 0.022 14.1 0.9 0.082 12.3 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.12 OEU15728.1 - 0.32 11.8 0.0 0.32 11.8 0.0 3.5 3 1 1 4 4 4 0 Methyltransferase domain IMUP PF15761.5 OEU15728.1 - 0.5 11.1 10.0 2.4 8.9 3.2 3.6 3 0 0 3 3 3 0 Immortalisation up-regulated protein Q_salvage PF10343.9 OEU15731.1 - 5.3e-51 173.9 0.4 1.6e-50 172.3 0.4 1.6 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family eIF2_C PF09173.11 OEU15732.1 - 1.6e-37 127.6 0.4 4.4e-37 126.2 0.4 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OEU15732.1 - 5.2e-23 81.6 1.3 2.9e-22 79.2 1.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OEU15732.1 - 5.9e-13 49.0 1.6 5.9e-13 49.0 1.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU15732.1 - 0.0049 16.9 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OEU15732.1 - 0.09 12.8 0.2 0.4 10.7 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Glyco_hydro_20 PF00728.22 OEU15733.1 - 4.3e-82 276.3 2.8 5e-81 272.8 2.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OEU15733.1 - 1.8e-09 38.3 0.0 3.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like GHL6 PF14871.6 OEU15733.1 - 0.076 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Peptidase_S41 PF03572.18 OEU15734.1 - 1.9e-40 138.1 1.0 1.2e-39 135.5 0.0 2.7 2 1 2 4 4 4 1 Peptidase family S41 PDZ_2 PF13180.6 OEU15734.1 - 1.9e-05 24.9 0.4 5.4e-05 23.4 0.4 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU15734.1 - 0.032 14.1 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 PDZ domain ETC_C1_NDUFA5 PF04716.14 OEU15734.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region VASP_tetra PF08776.11 OEU15734.1 - 0.34 10.5 4.5 0.79 9.3 4.5 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain Dus PF01207.17 OEU15735.1 - 8e-46 156.5 0.1 2.6e-40 138.4 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 OEU15735.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OEU15735.1 - 0.022 14.2 0.0 0.087 12.3 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein MLANA PF14991.6 OEU15735.1 - 0.26 11.6 1.2 0.84 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein melan-A ANAPC_CDC26 PF10471.9 OEU15735.1 - 0.63 10.9 9.8 0.072 13.9 3.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CbiJ PF02571.14 OEU15736.1 - 0.1 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK 2OG-FeII_Oxy_3 PF13640.6 OEU15738.1 - 1e-08 35.9 0.0 2.4e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SMK-1 PF04802.15 OEU15739.1 - 1.1e-40 139.5 0.0 2.3e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF4802 PF16060.5 OEU15739.1 - 0.026 14.7 1.8 0.042 14.0 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4802) YL1 PF05764.13 OEU15741.1 - 0.019 15.1 8.8 0.025 14.7 8.8 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S49 PF01343.18 OEU15743.1 - 1e-37 129.5 0.0 1.7e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 OEU15743.1 - 7.2e-23 81.3 0.7 3.2e-22 79.2 0.0 2.2 3 0 0 3 3 3 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 OEU15743.1 - 0.00041 19.4 0.0 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Macoilin PF09726.9 OEU15744.1 - 1.3 7.4 11.4 1.8 7.0 11.4 1.2 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 OEU15744.1 - 7.9 4.6 13.8 4.7 5.4 5.1 2.0 2 0 0 2 2 2 0 CDC45-like protein HA PF03457.14 OEU15745.1 - 5.1e-37 126.0 2.0 1e-18 67.4 0.1 2.1 2 0 0 2 2 2 2 Helicase associated domain Ribosomal_L6e_N PF03868.15 OEU15745.1 - 1.2 9.4 4.5 11 6.4 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L6, N-terminal domain CoA_transf_3 PF02515.17 OEU15746.1 - 0.12 11.5 0.5 0.21 10.7 0.5 1.3 1 0 0 1 1 1 0 CoA-transferase family III Spc24 PF08286.11 OEU15746.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.4 4 1 0 4 4 4 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 OEU15746.1 - 6.5 6.8 23.2 14 5.8 14.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Bromodomain PF00439.25 OEU15747.1 - 0.076 13.1 0.3 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 Bromodomain Hist_deacetyl PF00850.19 OEU15748.1 - 2.1e-38 132.6 0.0 3.3e-38 131.9 0.0 1.3 1 1 0 1 1 1 1 Histone deacetylase domain DUF2499 PF10693.9 OEU15750.1 - 3.3e-17 62.5 1.4 7e-17 61.5 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 OEU15751.1 - 3.5e-29 100.7 1.7 3.8e-29 100.5 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) TauD PF02668.16 OEU15752.1 - 5.6e-19 69.0 0.0 8.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OEU15752.1 - 0.0051 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 CsiD Pentapeptide PF00805.22 OEU15753.1 - 2.8e-14 52.4 4.3 1.1e-06 28.1 4.3 3.4 2 1 1 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OEU15753.1 - 4.5e-13 49.2 5.6 4.7e-07 29.9 0.3 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 OEU15753.1 - 1.9e-09 37.5 9.7 6.6e-06 26.2 1.5 2.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Reo_P9 PF06043.11 OEU15753.1 - 0.073 12.5 0.2 0.085 12.3 0.2 1.1 1 0 0 1 1 1 0 Reovirus P9-like family HSF_DNA-bind PF00447.17 OEU15754.1 - 8.4e-13 48.8 0.1 1.4e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding FXMR_C2 PF16098.5 OEU15754.1 - 0.14 12.7 0.7 0.4 11.2 0.7 1.7 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 ThiF PF00899.21 OEU15756.1 - 5.4e-60 202.8 0.0 1.3e-58 198.2 0.0 2.3 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OEU15756.1 - 4.5e-20 72.0 0.0 1.5e-19 70.4 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OEU15756.1 - 9.5e-11 42.1 2.7 2.2e-06 27.8 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OEU15756.1 - 0.0003 21.2 0.0 0.00074 19.9 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding E2_bind PF08825.10 OEU15756.1 - 0.00052 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 E2 binding domain Sacchrp_dh_NADP PF03435.18 OEU15756.1 - 0.013 15.8 3.5 1.3 9.3 0.1 3.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 OEU15756.1 - 0.096 12.3 1.4 0.91 9.1 0.0 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Chlam_vir PF05475.11 OEU15757.1 - 0.031 14.0 0.4 0.037 13.8 0.4 1.2 1 0 0 1 1 1 0 Pgp3 C-terminal domain Osw5 PF17062.5 OEU15758.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.2 1 0 0 1 1 1 0 Outer spore wall 5 Na_Ca_ex PF01699.24 OEU15759.1 - 1.2e-34 119.5 32.3 1.4e-17 64.0 7.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Thioredoxin PF00085.20 OEU15760.1 - 6e-06 26.2 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 OEU15760.1 - 0.084 11.8 0.1 0.29 10.0 0.1 1.7 1 1 1 2 2 2 0 Phosducin CCSAP PF15748.5 OEU15760.1 - 0.36 11.0 3.9 0.48 10.5 3.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CFIA_Pcf11 PF11526.8 OEU15760.1 - 8.7 6.9 10.1 2.9 8.5 6.7 2.0 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 EamA PF00892.20 OEU15763.1 - 4.4e-21 75.5 26.3 1.5e-11 44.6 7.2 2.8 3 0 0 3 3 3 2 EamA-like transporter family Pro_isomerase PF00160.21 OEU15764.1 - 7.7e-33 114.0 0.0 8.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HtrL_YibB PF09612.10 OEU15765.1 - 1e-08 35.0 0.1 1.6e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Exostosin PF03016.15 OEU15766.1 - 4.9e-18 65.4 0.0 4.5e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Exostosin family Sulfatase_C PF14707.6 OEU15767.1 - 5.6e-05 23.9 0.0 7.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 OEU15767.1 - 0.00011 22.1 0.0 0.00042 20.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function Sulfatase PF00884.23 OEU15769.1 - 6.5e-18 65.2 1.2 2.7e-16 59.9 1.2 2.8 1 1 0 1 1 1 1 Sulfatase DUF4047 PF13256.6 OEU15771.1 - 0.033 14.4 0.1 0.047 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) S1-P1_nuclease PF02265.16 OEU15771.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 S1/P1 Nuclease P4Ha_N PF08336.11 OEU15772.1 - 0.0072 16.3 0.3 0.011 15.7 0.3 1.2 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Coagulase PF08764.10 OEU15772.1 - 0.029 14.6 2.5 0.037 14.2 2.5 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Ran-binding PF05508.11 OEU15772.1 - 0.034 13.1 0.6 0.046 12.7 0.6 1.1 1 0 0 1 1 1 0 RanGTP-binding protein T4_Rnl2_C PF18043.1 OEU15772.1 - 0.051 13.7 1.1 0.082 13.1 0.5 1.6 1 1 0 1 1 1 0 T4 RNA ligase 2 C-terminal Bombinin PF05298.11 OEU15772.1 - 0.064 12.9 0.8 0.099 12.3 0.7 1.4 1 1 0 1 1 1 0 Bombinin Pex24p PF06398.11 OEU15772.1 - 0.22 10.4 2.2 0.21 10.5 0.6 1.6 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF5595 PF18077.1 OEU15772.1 - 0.27 11.3 2.8 1.2 9.3 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) FlaC_arch PF05377.11 OEU15772.1 - 0.3 11.5 4.4 0.31 11.5 3.0 1.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) SH3_3 PF08239.11 OEU15773.1 - 0.00022 21.5 0.3 0.007 16.6 0.2 3.5 4 0 0 4 4 4 1 Bacterial SH3 domain Mre11_DNA_bind PF04152.14 OEU15774.1 - 1.8e-33 116.2 0.4 1.8e-33 116.2 0.4 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OEU15774.1 - 7.3e-10 39.7 7.2 7.7e-09 36.3 7.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OEU15774.1 - 3.1e-06 27.5 0.0 0.00099 19.3 0.0 3.0 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Pro_dh PF01619.18 OEU15774.1 - 0.058 12.9 0.0 3.5 7.1 0.0 2.4 3 0 0 3 3 3 0 Proline dehydrogenase PBP1_TM PF14812.6 OEU15774.1 - 7.5 7.0 11.3 20 5.6 11.3 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GDP_Man_Dehyd PF16363.5 OEU15776.1 - 1.3e-68 231.9 0.0 1.5e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU15776.1 - 8.8e-56 189.1 0.0 1.1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU15776.1 - 5.9e-22 78.0 0.0 7.9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OEU15776.1 - 2.4e-20 72.8 0.0 2.5e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OEU15776.1 - 1.1e-19 70.7 0.0 5.7e-13 48.6 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU15776.1 - 5.2e-17 61.9 0.0 6.5e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OEU15776.1 - 0.047 13.1 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DUF3109 PF11307.8 OEU15776.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) Sacchrp_dh_NADP PF03435.18 OEU15776.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PPP4R2 PF09184.11 OEU15777.1 - 2.8e-05 23.9 4.8 2.8e-05 23.9 4.8 5.6 3 2 2 6 6 6 1 PPP4R2 ECR1_N PF14382.6 OEU15778.1 - 4e-11 42.5 0.2 8.3e-11 41.5 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 OEU15778.1 - 1.6e-08 35.1 0.1 0.00014 22.5 0.0 2.6 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 DNA_pol_B_palm PF14792.6 OEU15779.1 - 1.3e-20 73.7 0.0 6.7e-19 68.2 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 OEU15779.1 - 2.3e-20 72.5 0.3 6.6e-20 71.0 0.3 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OEU15779.1 - 8.4e-12 44.7 0.0 1.9e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OEU15779.1 - 1e-08 35.4 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 OEU15779.1 - 0.00085 19.9 0.0 1.4 9.5 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix domain BRCT_2 PF16589.5 OEU15779.1 - 0.0035 17.7 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 OEU15779.1 - 0.012 15.9 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain LIG3_BRCT PF16759.5 OEU15779.1 - 0.093 13.0 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Chloroa_b-bind PF00504.21 OEU15780.1 - 7.6e-35 120.8 0.1 1.1e-34 120.3 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pkinase PF00069.25 OEU15781.1 - 8.9e-50 169.5 0.1 9.8e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15781.1 - 3.9e-27 95.2 0.0 4.4e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU15781.1 - 0.0028 17.0 2.0 0.0073 15.7 2.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OEU15781.1 - 0.0065 16.1 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OEU15781.1 - 0.035 14.0 0.6 0.041 13.8 0.6 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MafB19-deam PF14437.6 OEU15782.1 - 3.5e-25 88.3 0.4 3.7e-24 85.0 0.4 2.0 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 OEU15782.1 - 6e-22 77.4 0.6 1.5e-20 72.9 0.6 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 OEU15782.1 - 1.4e-05 25.2 0.3 3.7e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 OEU15782.1 - 0.00015 21.9 0.2 0.00022 21.4 0.0 1.5 2 0 0 2 2 2 1 APOBEC3 APOBEC2 PF18772.1 OEU15782.1 - 0.00045 20.3 0.1 0.00072 19.6 0.1 1.3 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 OEU15782.1 - 0.00051 20.0 0.2 0.00059 19.8 0.2 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 OEU15782.1 - 0.00078 19.6 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 NAD1 PF18778.1 OEU15782.1 - 0.0021 18.1 0.1 0.0037 17.4 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Inv-AAD PF18785.1 OEU15782.1 - 0.021 14.7 0.2 0.048 13.5 0.2 1.7 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Toxin-deaminase PF14424.6 OEU15782.1 - 0.051 13.7 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF2162 PF09930.9 OEU15782.1 - 0.18 11.2 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) SR-25 PF10500.9 OEU15783.1 - 0.03 14.0 2.3 0.047 13.3 2.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HHH_8 PF14716.6 OEU15783.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMUP PF15761.5 OEU15783.1 - 0.43 11.3 4.5 2.4 8.9 0.6 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein PAS_9 PF13426.7 OEU15785.1 - 3.1e-08 33.8 1.4 1.2e-07 31.9 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OEU15785.1 - 0.0003 20.7 0.0 0.0003 20.7 0.0 3.2 2 1 0 2 2 2 1 PAS fold bZIP_1 PF00170.21 OEU15785.1 - 0.0011 19.0 5.3 0.0028 17.7 5.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAS_8 PF13188.7 OEU15785.1 - 0.026 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain Med15 PF09606.10 OEU15785.1 - 2.9 6.4 93.4 0.93 8.1 9.3 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal AIG2_2 PF13772.6 OEU15786.1 - 0.0015 18.9 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Aldose_epim PF01263.20 OEU15787.1 - 2.8e-27 95.8 0.0 4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Glycos_transf_2 PF00535.26 OEU15788.1 - 1.1e-13 51.4 0.5 3.2e-13 49.8 0.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OEU15788.1 - 0.017 15.1 0.0 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OEU15788.1 - 0.081 13.4 0.1 2.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 GRP PF07172.11 OEU15789.1 - 0.0012 19.5 1.5 0.0016 19.1 1.5 1.2 1 0 0 1 1 1 1 Glycine rich protein family MA3 PF02847.17 OEU15790.1 - 2.3e-34 117.7 2.6 1.1e-19 70.4 0.1 2.3 2 0 0 2 2 2 2 MA3 domain MMS19_C PF12460.8 OEU15790.1 - 0.039 13.1 0.1 7 5.6 0.0 2.1 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Proteasome PF00227.26 OEU15791.1 - 1.3e-35 122.6 0.0 1.6e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU15791.1 - 1.1e-13 50.6 0.1 1.7e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DnaJ PF00226.31 OEU15792.1 - 9.8e-11 41.6 0.0 2.2e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain DUF3114 PF11311.8 OEU15792.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) PAP_fibrillin PF04755.12 OEU15793.1 - 1.9e-17 63.8 0.0 5.6e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 PAP_fibrillin Fungal_trans_2 PF11951.8 OEU15793.1 - 0.03 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain dCMP_cyt_deam_1 PF00383.23 OEU15794.1 - 2e-09 37.2 0.1 2.8e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OEU15794.1 - 0.00083 19.1 0.1 0.0012 18.6 0.1 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 OEU15794.1 - 0.0047 16.8 0.1 0.0073 16.2 0.1 1.4 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase CPBP PF02517.16 OEU15795.1 - 2.4e-06 27.8 2.1 0.00016 21.9 0.6 3.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Opi1 PF08618.10 OEU15795.1 - 0.017 14.4 0.4 0.037 13.3 0.4 1.5 1 0 0 1 1 1 0 Transcription factor Opi1 Peptidase_M56 PF05569.11 OEU15795.1 - 0.11 11.6 3.0 0.69 9.0 0.1 2.7 3 0 0 3 3 3 0 BlaR1 peptidase M56 Aminotran_1_2 PF00155.21 OEU15796.1 - 6.1e-88 295.4 0.0 7.1e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Transglut_core PF01841.19 OEU15797.1 - 2.8e-08 34.2 0.0 6.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Cas6_N PF17952.1 OEU15797.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Cas6 N-terminal domain Spt20 PF12090.8 OEU15798.1 - 0.12 11.9 12.5 0.023 14.3 3.9 2.5 2 0 0 2 2 2 0 Spt20 family N1221 PF07923.13 OEU15798.1 - 0.2 10.8 8.7 17 4.5 5.8 3.8 2 1 0 2 2 2 0 N1221-like protein PAP_RNA-bind PF04926.15 OEU15798.1 - 2 8.1 7.0 0.54 9.9 0.9 2.6 3 0 0 3 3 3 0 Poly(A) polymerase predicted RNA binding domain DUF4834 PF16118.5 OEU15798.1 - 3.2 8.8 7.3 11 7.0 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Kelch_6 PF13964.6 OEU15799.1 - 2.7e-13 49.7 13.0 0.0023 18.2 0.2 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 OEU15799.1 - 5.1e-10 39.4 17.2 0.0001 22.5 0.5 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OEU15799.1 - 3.2e-06 26.9 2.5 1.2 9.2 0.3 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 OEU15799.1 - 9.4e-06 25.6 16.1 0.012 15.6 0.6 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OEU15799.1 - 0.068 13.2 12.0 0.2 11.7 0.1 4.6 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 OEU15799.1 - 0.15 11.7 17.2 5.9 6.6 0.2 6.2 7 0 0 7 7 7 0 Kelch motif CRAL_TRIO PF00650.20 OEU15800.1 - 2.6e-08 33.7 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain H_PPase PF03030.16 OEU15801.1 - 1.2e-253 843.6 35.6 1.4e-253 843.3 35.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase SnoaL_2 PF12680.7 OEU15802.1 - 0.055 14.1 0.0 0.13 12.9 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain SET PF00856.28 OEU15803.1 - 0.077 13.4 0.0 0.077 13.4 0.0 2.4 2 2 0 2 2 2 0 SET domain Sod_Cu PF00080.20 OEU15804.1 - 4.8e-35 120.8 0.5 5.9e-35 120.5 0.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) GTP_EFTU PF00009.27 OEU15805.1 - 8.7e-57 191.8 0.3 1.1e-56 191.4 0.3 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OEU15805.1 - 3.4e-26 91.7 0.1 7.1e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OEU15805.1 - 3.3e-16 59.4 2.2 3.3e-16 59.4 2.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU15805.1 - 0.00012 22.2 0.1 0.00032 20.8 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 OEU15805.1 - 0.0047 16.5 0.0 0.022 14.3 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OEU15805.1 - 0.014 15.1 0.4 0.34 10.6 0.4 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S8 PF00410.19 OEU15805.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S8 RsgA_GTPase PF03193.16 OEU15805.1 - 0.055 13.4 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Macoilin PF09726.9 OEU15806.1 - 0.38 9.3 17.5 0.51 8.8 17.5 1.1 1 0 0 1 1 1 0 Macoilin family ETRAMP PF09716.10 OEU15806.1 - 7.7 6.7 8.3 3.6e+02 1.3 0.0 3.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Branch PF02485.21 OEU15807.1 - 1.1e-06 28.3 0.9 2.5e-06 27.2 0.1 1.8 1 1 1 2 2 2 1 Core-2/I-Branching enzyme HMG_box PF00505.19 OEU15810.1 - 2e-27 95.4 14.6 1.6e-14 54.1 1.6 2.5 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU15810.1 - 8.6e-20 71.1 13.4 2.2e-13 50.6 3.7 2.1 2 0 0 2 2 2 2 HMG-box domain DUF2057 PF09829.9 OEU15810.1 - 0.3 11.2 4.2 0.11 12.7 1.0 1.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) S4 PF01479.25 OEU15812.1 - 7.4e-09 35.2 0.0 1.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OEU15812.1 - 8.1e-08 33.1 0.8 1e-07 32.8 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain CCT PF06203.14 OEU15813.1 - 1.8e-15 56.7 13.2 1.8e-15 56.7 13.2 1.7 2 0 0 2 2 2 1 CCT motif PT PF04886.12 OEU15815.1 - 1.6e-17 62.7 66.9 4.3e-05 22.9 10.8 5.3 2 2 1 3 3 3 3 PT repeat KAR9 PF08580.10 OEU15815.1 - 3.5 6.0 30.2 4.4 5.7 30.2 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_L7Ae PF01248.26 OEU15816.1 - 4.4e-21 74.4 0.7 1.2e-20 73.0 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OEU15816.1 - 0.0015 18.6 0.4 0.0055 16.8 0.1 2.0 1 1 1 2 2 2 1 RNase P subunit Pop3 WD40 PF00400.32 OEU15817.1 - 5.6e-38 128.3 11.0 2.2e-08 34.6 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU15817.1 - 1.7e-12 47.4 0.1 0.0059 16.9 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU15817.1 - 4.6e-09 36.4 0.0 4.2e-05 23.5 0.0 3.1 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OEU15817.1 - 8.5e-09 34.6 1.3 0.011 14.5 0.0 4.2 3 1 2 5 5 5 3 Nucleoporin Nup120/160 VID27 PF08553.10 OEU15817.1 - 0.0003 20.0 0.0 0.0041 16.2 0.0 2.3 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 OEU15817.1 - 0.0019 17.2 0.1 0.18 10.7 0.0 3.0 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OEU15817.1 - 0.011 15.1 0.0 0.17 11.1 0.0 2.5 1 1 1 3 3 3 0 WD40-like domain Frtz PF11768.8 OEU15817.1 - 0.017 13.5 0.0 0.069 11.5 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 OEU15817.1 - 0.019 13.5 0.0 0.059 11.9 0.0 1.8 2 1 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 OEU15817.1 - 0.043 12.7 0.2 2.5 6.9 0.1 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 OEU15817.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glyco_hydro_99 PF16317.5 OEU15818.1 - 1.1e-34 120.1 0.9 5.3e-34 117.9 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 OEU15818.1 - 1.4e-11 44.4 0.0 5.8e-11 42.4 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase WbsX DUF5010 PF16402.5 OEU15818.1 - 0.001 18.0 0.0 0.0027 16.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5010) PAP_fibrillin PF04755.12 OEU15819.1 - 3.3e-15 56.6 5.7 1.3e-12 48.1 0.6 3.3 2 2 1 3 3 3 2 PAP_fibrillin FKBP_C PF00254.28 OEU15821.1 - 6.6e-19 68.0 0.0 8.5e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF179 PF02622.15 OEU15822.1 - 1.2e-13 51.4 0.0 1.3e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Med3 PF11593.8 OEU15823.1 - 0.0022 17.3 5.4 0.004 16.4 5.4 1.5 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 OEU15823.1 - 0.17 12.0 9.2 0.043 13.9 4.8 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Lin-8 PF03353.15 OEU15823.1 - 1 8.9 7.9 2 7.9 7.9 1.6 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist PP2C PF00481.21 OEU15825.1 - 4e-16 59.4 0.0 4.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU15825.1 - 0.016 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) CS PF04969.16 OEU15826.1 - 2.3e-08 34.9 0.4 4.9e-08 33.9 0.4 1.6 1 1 0 1 1 1 1 CS domain DUF3405 PF11885.8 OEU15828.1 - 0.013 14.2 0.0 0.014 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) PPR_1 PF12854.7 OEU15829.1 - 2.9e-42 142.0 0.0 8.8e-05 22.1 0.0 11.7 10 2 0 10 10 10 8 PPR repeat PPR_2 PF13041.6 OEU15829.1 - 2.2e-39 133.4 4.8 2.3e-06 27.7 0.0 9.7 5 3 4 9 9 9 8 PPR repeat family PPR_3 PF13812.6 OEU15829.1 - 2e-29 101.4 0.5 0.003 17.6 0.0 9.7 5 4 5 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.20 OEU15829.1 - 1.7e-18 65.5 13.9 0.2 12.0 0.0 12.5 10 2 0 10 10 10 5 PPR repeat PPR_long PF17177.4 OEU15829.1 - 4.8e-15 55.5 2.0 0.011 15.1 0.0 5.2 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP DUF3168 PF11367.8 OEU15829.1 - 0.00034 20.8 6.4 0.061 13.5 0.0 5.2 4 2 1 5 5 5 1 Protein of unknown function (DUF3168) MRP-S27 PF10037.9 OEU15829.1 - 0.0036 16.2 0.0 2.6 6.8 0.0 3.8 3 1 1 4 4 4 1 Mitochondrial 28S ribosomal protein S27 DUF3701 PF12482.8 OEU15829.1 - 0.013 15.5 1.9 0.71 10.0 0.0 3.7 3 1 0 4 4 4 0 Phage integrase protein LPD11 PF18824.1 OEU15829.1 - 0.02 15.0 0.3 8.3 6.6 0.0 4.7 4 1 1 5 5 5 0 Large polyvalent protein-associated domain 11 TetR_C_27 PF17935.1 OEU15829.1 - 0.056 13.5 0.2 14 5.8 0.0 4.0 4 1 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain RNA_pol_Rpb1_4 PF05000.17 OEU15829.1 - 0.25 11.3 3.4 7.9 6.5 0.2 4.0 4 1 0 5 5 5 0 RNA polymerase Rpb1, domain 4 TPR_MalT PF17874.1 OEU15829.1 - 1.5 8.1 4.1 28 3.9 0.1 3.2 2 2 2 4 4 4 0 MalT-like TPR region Guanylate_cyc PF00211.20 OEU15830.1 - 2.2e-45 154.5 0.0 4.9e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 OEU15830.1 - 9.7e-29 100.8 0.8 2.4e-28 99.5 0.8 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TssO PF17561.2 OEU15830.1 - 0.18 11.9 4.3 2.4 8.3 1.2 2.6 2 0 0 2 2 2 0 Type VI secretion system, TssO Tam41_Mmp37 PF09139.11 OEU15831.1 - 1.4e-11 44.4 0.4 1.6e-11 44.3 0.4 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial TMEM173 PF15009.6 OEU15831.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 173 CybS PF05328.12 OEU15831.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Chalcone_3 PF16036.5 OEU15833.1 - 1.5e-12 48.0 0.0 5.1e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Chalcone isomerase-like DUF681 PF05080.12 OEU15833.1 - 0.099 13.3 1.7 0.18 12.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF681) DSPn PF14671.6 OEU15833.1 - 0.14 12.6 0.2 0.26 11.7 0.2 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half EamA PF00892.20 OEU15834.1 - 1.4e-14 54.4 18.2 1.2e-08 35.2 9.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family Allatostatin PF05953.12 OEU15834.1 - 0.2 12.3 0.1 0.44 11.3 0.1 1.5 1 0 0 1 1 1 0 Allatostatin GSDH PF07995.11 OEU15835.1 - 3.8e-37 128.3 0.0 6.8e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU15835.1 - 1.7e-09 37.4 0.0 4.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 PKD domain EF-hand_7 PF13499.6 OEU15837.1 - 1.4e-13 51.1 0.7 1.4e-13 51.1 0.7 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU15837.1 - 3.2e-12 45.1 1.2 1.5e-06 27.4 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OEU15837.1 - 3.5e-12 46.0 2.1 3.1e-10 39.7 0.4 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU15837.1 - 2.4e-10 39.5 0.4 0.00017 21.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU15837.1 - 5e-08 32.1 2.2 0.00071 19.0 0.4 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 OEU15837.1 - 0.00029 21.1 0.0 0.00049 20.4 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OEU15837.1 - 0.0048 16.8 1.2 0.23 11.4 0.4 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 OEU15838.1 - 7e-16 58.3 0.0 6.2e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU15838.1 - 1.2e-06 28.2 0.0 1.7e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 OEU15838.1 - 0.00044 19.3 0.2 0.046 12.7 0.0 2.2 1 1 1 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OEU15838.1 - 0.00083 18.9 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU15838.1 - 0.0021 18.0 0.0 0.49 10.3 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 OEU15838.1 - 0.0049 16.2 0.0 0.024 14.0 0.0 2.1 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.23 OEU15838.1 - 0.053 13.6 0.1 0.5 10.4 0.0 2.2 1 1 1 2 2 2 0 Dynamin family DUF2431 PF10354.9 OEU15839.1 - 6.7e-34 117.6 0.3 1.1e-33 116.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Rhomboid PF01694.22 OEU15840.1 - 3.2e-14 53.2 14.0 9.4e-14 51.7 14.0 1.7 1 1 0 1 1 1 1 Rhomboid family Spt20 PF12090.8 OEU15840.1 - 5.3 6.6 20.8 9 5.8 20.8 1.3 1 0 0 1 1 1 0 Spt20 family MgsA_C PF12002.8 OEU15840.1 - 5.7 6.9 5.4 8.7 6.3 5.4 1.2 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF2428 PF10350.9 OEU15842.1 - 8.3e-34 117.1 0.3 1.3e-32 113.1 0.1 2.7 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 OEU15842.1 - 1.6e-10 40.3 4.7 0.11 12.9 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 OEU15842.1 - 1.7e-08 34.8 0.3 0.05 14.0 0.0 4.2 3 0 0 3 3 3 3 HEAT repeats Arm PF00514.23 OEU15842.1 - 0.00063 19.7 4.8 0.059 13.4 0.0 4.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 OEU15842.1 - 0.00069 19.7 0.8 0.27 11.3 0.0 3.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OEU15842.1 - 0.057 14.0 2.6 15 6.2 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT_PBS PF03130.16 OEU15842.1 - 0.078 13.7 0.0 18 6.4 0.0 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF2796 PF10986.8 OEU15843.1 - 0.25 11.3 7.4 0.079 12.9 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) GET2 PF08690.10 OEU15843.1 - 1.1 8.8 9.8 1.7 8.2 9.8 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Macoilin PF09726.9 OEU15843.1 - 3.6 6.0 14.8 4.4 5.7 14.8 1.0 1 0 0 1 1 1 0 Macoilin family IstB_IS21_ATP PF08483.11 OEU15844.1 - 0.0095 15.8 0.2 0.021 14.7 0.2 1.6 1 0 0 1 1 1 1 IstB-like ATP binding N-terminal Fib_alpha PF08702.10 OEU15844.1 - 0.21 11.8 4.6 0.34 11.1 4.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OEU15844.1 - 0.78 10.4 7.0 7.5 7.3 2.0 3.0 1 1 1 2 2 2 0 SlyX 4HBT PF03061.22 OEU15847.1 - 0.0022 18.3 0.1 0.37 11.2 0.0 3.5 3 0 0 3 3 3 1 Thioesterase superfamily DUF647 PF04884.14 OEU15848.1 - 2.4e-72 243.5 0.0 3.6e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis 2TM PF13239.6 OEU15848.1 - 0.1 12.9 1.6 1.2 9.5 0.2 2.4 2 0 0 2 2 2 0 2TM domain Orf78 PF06024.12 OEU15849.1 - 0.00097 19.4 0.7 0.00097 19.4 0.7 2.1 1 1 1 2 2 2 1 Orf78 (ac78) Shisa PF13908.6 OEU15849.1 - 0.0015 18.8 1.1 0.0018 18.6 1.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Renin_r PF07850.14 OEU15849.1 - 0.0026 18.3 2.0 0.0046 17.5 0.4 1.9 2 0 0 2 2 2 1 Renin receptor-like protein SARAF PF06682.12 OEU15849.1 - 0.0037 17.0 1.3 0.0061 16.2 1.3 1.5 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis YukC PF10140.9 OEU15849.1 - 0.0038 16.1 0.7 0.0055 15.6 0.7 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC TRIQK PF15168.6 OEU15849.1 - 0.0044 16.9 1.6 0.026 14.4 0.5 2.1 2 0 0 2 2 2 1 Triple QxxK/R motif-containing protein family CrgA PF06781.12 OEU15849.1 - 0.0077 16.3 4.2 0.0078 16.2 0.3 2.1 2 0 0 2 2 2 1 Cell division protein CrgA DUF3377 PF11857.8 OEU15849.1 - 0.0091 15.9 0.2 0.018 14.9 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3377) DUF2207 PF09972.9 OEU15849.1 - 0.011 14.5 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UL45 PF05473.12 OEU15849.1 - 0.011 15.3 0.5 0.023 14.4 0.0 1.6 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like UNC-50 PF05216.13 OEU15849.1 - 0.012 15.1 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 UNC-50 family SUR7 PF06687.12 OEU15849.1 - 0.03 14.0 1.2 0.045 13.4 1.2 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF5305 PF17231.2 OEU15849.1 - 0.03 13.7 2.5 0.042 13.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4366 PF14283.6 OEU15849.1 - 0.03 14.3 2.4 0.065 13.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF3671 PF12420.8 OEU15849.1 - 0.043 13.9 1.1 0.061 13.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2371 PF10177.9 OEU15849.1 - 0.046 13.9 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DcuC PF03606.15 OEU15849.1 - 0.051 12.0 0.6 0.054 12.0 0.6 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Cytochrom_B_N_2 PF13631.6 OEU15849.1 - 0.053 13.5 1.3 0.072 13.1 0.3 1.7 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF3899 PF13038.6 OEU15849.1 - 0.095 13.2 0.3 0.16 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Gaa1 PF04114.14 OEU15849.1 - 0.14 11.2 3.1 0.15 11.0 3.1 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component TMEM154 PF15102.6 OEU15849.1 - 0.16 11.9 7.6 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family SID-1_RNA_chan PF13965.6 OEU15849.1 - 0.17 10.2 2.0 0.22 9.9 2.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DcuA_DcuB PF03605.14 OEU15849.1 - 0.2 10.5 2.6 0.25 10.2 2.6 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Glt_symporter PF03616.14 OEU15849.1 - 0.21 10.3 1.0 0.23 10.1 1.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter 7TM_GPCR_Sru PF10322.9 OEU15849.1 - 0.27 10.5 6.6 0.34 10.2 6.1 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF3112 PF11309.8 OEU15849.1 - 0.35 10.3 4.5 0.19 11.1 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) LAP1C PF05609.12 OEU15849.1 - 0.35 9.9 3.9 0.088 11.9 0.5 1.6 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Mucin PF01456.17 OEU15849.1 - 0.75 9.8 11.4 2 8.4 11.4 1.7 1 1 0 1 1 1 0 Mucin-like glycoprotein OppC_N PF12911.7 OEU15849.1 - 1.6 8.8 4.1 3.2 7.8 4.1 1.5 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C GET2 PF08690.10 OEU15849.1 - 1.8 8.1 8.1 0.27 10.9 3.7 1.6 1 1 1 2 2 2 0 GET complex subunit GET2 Fasciclin PF02469.22 OEU15850.1 - 1.5e-17 64.0 0.0 2.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU15850.1 - 0.00012 22.8 0.5 0.001 19.8 0.5 2.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DinB_2 PF12867.7 OEU15851.1 - 0.04 14.4 0.1 0.096 13.2 0.1 1.6 1 1 0 1 1 1 0 DinB superfamily DUF4611 PF15387.6 OEU15851.1 - 1.2 9.4 10.8 1.3 9.2 9.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF848 PF05852.11 OEU15851.1 - 1.4 9.0 6.1 2.6 8.2 6.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Mntp PF02659.15 OEU15853.1 - 5.2e-06 26.3 2.3 0.0057 16.4 2.3 2.2 2 0 0 2 2 2 2 Putative manganese efflux pump RGS12_us1 PF16613.5 OEU15853.1 - 0.069 13.5 0.8 0.11 12.8 0.8 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 COX16 PF14138.6 OEU15853.1 - 0.13 12.7 0.0 0.65 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 LptF_LptG PF03739.14 OEU15853.1 - 7 5.4 8.0 0.38 9.6 1.7 1.9 2 2 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Ras PF00071.22 OEU15854.1 - 5.9e-47 159.3 0.0 7.5e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU15854.1 - 4.5e-30 104.3 0.0 1.3e-29 102.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU15854.1 - 8.4e-09 35.1 0.0 1.8e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU15854.1 - 3.4e-05 23.9 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU15854.1 - 8.4e-05 22.2 0.2 0.007 15.9 0.2 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU15854.1 - 0.0011 19.0 0.1 0.0052 16.7 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OEU15854.1 - 0.0029 18.0 0.0 0.0074 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OEU15854.1 - 0.0072 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU15854.1 - 0.0079 16.5 0.1 0.023 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 OEU15854.1 - 0.0099 15.7 0.4 0.51 10.1 0.0 2.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OEU15854.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OEU15854.1 - 0.054 12.9 0.2 0.079 12.4 0.2 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 OEU15854.1 - 0.08 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OEU15854.1 - 0.098 13.2 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 OEU15854.1 - 0.11 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain YadA_anchor PF03895.15 OEU15854.1 - 0.12 12.4 0.3 9.1 6.5 0.1 2.3 2 0 0 2 2 2 0 YadA-like membrane anchor domain TniB PF05621.11 OEU15854.1 - 0.13 11.6 0.1 0.31 10.4 0.0 1.7 1 1 1 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OEU15854.1 - 0.19 11.2 0.1 3.5 7.1 0.0 2.6 2 1 1 3 3 3 0 Ferrous iron transport protein B DHHC PF01529.20 OEU15855.1 - 6.6e-36 123.4 13.0 6.6e-36 123.4 13.0 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Nucleoporin2 PF04096.14 OEU15856.1 - 2.5e-34 118.5 0.0 2.8e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin autopeptidase Formyl_trans_N PF00551.19 OEU15857.1 - 1.6e-35 122.5 0.1 2e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OEU15857.1 - 4.7e-05 23.1 0.0 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 OEU15857.1 - 0.00018 21.4 0.1 0.00082 19.3 0.0 2.1 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 OEU15857.1 - 0.082 13.5 0.0 0.52 10.9 0.0 2.1 2 0 0 2 2 2 0 ACT domain COX4 PF02936.14 OEU15858.1 - 5.7e-07 29.6 0.0 7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HemN_C PF06969.16 OEU15859.1 - 0.055 13.5 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 HemN C-terminal domain AMP-binding PF00501.28 OEU15860.1 - 7.1e-83 278.5 0.1 8.7e-83 278.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CW_binding_2 PF04122.12 OEU15860.1 - 0.0079 16.8 0.0 0.026 15.2 0.0 1.9 1 0 0 1 1 1 1 Putative cell wall binding repeat 2 DUF4205 PF13898.6 OEU15861.1 - 2e-34 119.0 0.0 2.3e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) GCV_T PF01571.21 OEU15863.1 - 7.6e-05 22.2 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain Rrp44_CSD1 PF17216.3 OEU15863.1 - 0.51 10.0 5.4 0.17 11.6 0.4 2.2 2 0 0 2 2 2 0 Rrp44-like cold shock domain UCH PF00443.29 OEU15864.1 - 1.1e-64 218.4 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU15864.1 - 2e-21 76.9 0.1 8.1e-19 68.4 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glucodextran_C PF09985.9 OEU15864.1 - 0.15 11.5 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase DNA_ligase_ZBD PF03119.16 OEU15864.1 - 0.25 11.4 2.3 8.2 6.5 0.0 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 OEU15864.1 - 1.7 8.9 3.6 24 5.2 1.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L19e PF01280.20 OEU15865.1 - 1.2e-59 200.5 7.6 1.2e-59 200.5 7.6 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e EXS PF03124.14 OEU15866.1 - 9.6e-29 100.7 0.5 1.1e-28 100.6 0.5 1.0 1 0 0 1 1 1 1 EXS family EXS PF03124.14 OEU15867.1 - 2.3e-06 27.2 4.3 2.3e-06 27.2 4.3 1.5 2 0 0 2 2 2 1 EXS family DnaJ PF00226.31 OEU15868.1 - 1.2e-10 41.3 0.0 3.5e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain SAP PF02037.27 OEU15868.1 - 3.5e-06 26.6 2.6 0.017 14.9 0.0 3.7 4 0 0 4 4 4 2 SAP domain Rho_N PF07498.12 OEU15868.1 - 0.0018 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain zf-LITAF-like PF10601.9 OEU15868.1 - 0.97 9.8 13.9 1.1 9.6 10.9 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain UPF0047 PF01894.17 OEU15869.1 - 8.2e-32 109.8 0.1 2e-31 108.5 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 Methyltransf_16 PF10294.9 OEU15870.1 - 7.3e-06 25.8 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase dsrm PF00035.26 OEU15872.1 - 3.6e-06 27.6 0.1 7.1e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif BAG PF02179.16 OEU15873.1 - 2.2e-07 31.2 0.2 4.9e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OEU15873.1 - 0.002 17.8 0.0 3 7.6 0.0 3.0 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 OEU15873.1 - 0.014 15.8 0.5 0.034 14.6 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Enolase_C PF00113.22 OEU15873.1 - 0.028 13.7 1.8 0.05 12.8 1.8 1.4 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain DUF4497 PF14924.6 OEU15873.1 - 0.039 14.4 0.3 0.12 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) V-ATPase_H_N PF03224.14 OEU15874.1 - 2.7e-15 56.5 13.2 2.1e-13 50.3 13.2 3.0 1 1 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OEU15874.1 - 2.4e-11 43.8 0.1 5.8e-10 39.3 0.0 3.0 2 1 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 OEU15874.1 - 0.049 13.7 1.4 0.6 10.2 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2897 PF11446.8 OEU15875.1 - 0.28 11.1 0.9 0.66 9.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) NIF PF03031.18 OEU15876.1 - 3.6e-34 117.8 0.0 4.2e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.25 OEU15878.1 - 4.6e-49 167.2 0.2 5.6e-49 166.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15878.1 - 2.7e-27 95.7 0.0 3.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU15878.1 - 0.0021 16.9 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OEU15878.1 - 0.014 14.7 0.5 0.082 12.2 0.4 2.3 1 1 1 2 2 2 0 Kinase-like COPI_C PF06957.11 OEU15878.1 - 0.092 11.5 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TarH PF02203.15 OEU15879.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue CaKB PF03185.15 OEU15879.1 - 0.13 11.9 0.2 0.28 10.8 0.1 1.5 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit Lipase_GDSL_2 PF13472.6 OEU15880.1 - 0.039 14.3 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2973 PF11189.8 OEU15881.1 - 0.1 12.7 0.0 0.36 10.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2973) BUD22 PF09073.10 OEU15882.1 - 0.0028 17.1 13.7 0.0033 16.8 13.7 1.1 1 0 0 1 1 1 1 BUD22 DUF755 PF05501.11 OEU15882.1 - 0.0098 16.2 6.0 0.0098 16.2 6.0 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF755) zf-RING_2 PF13639.6 OEU15882.1 - 0.024 15.0 8.3 0.038 14.3 8.3 1.3 1 0 0 1 1 1 0 Ring finger domain PAP1 PF08601.10 OEU15882.1 - 0.2 11.4 24.8 0.26 11.0 24.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 zf-rbx1 PF12678.7 OEU15882.1 - 0.21 11.9 4.2 3.6 8.0 0.7 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Nop14 PF04147.12 OEU15882.1 - 3 6.0 13.7 3.8 5.6 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family SPX PF03105.19 OEU15882.1 - 7.4 6.4 22.5 11 5.8 22.5 1.3 1 0 0 1 1 1 0 SPX domain FTHFS PF01268.19 OEU15883.1 - 1e-150 502.6 2.9 4.7e-138 460.8 0.8 2.0 1 1 1 2 2 2 2 Formate--tetrahydrofolate ligase Anoctamin PF04547.12 OEU15884.1 - 5.7e-88 295.7 17.9 4.9e-48 164.1 12.7 2.2 2 0 0 2 2 2 2 Calcium-activated chloride channel DUF3611 PF12263.8 OEU15885.1 - 6.9e-14 52.1 5.4 1.2e-13 51.3 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) PBP1_TM PF14812.6 OEU15885.1 - 0.013 15.8 1.5 0.021 15.2 1.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORF45 PF17620.2 OEU15885.1 - 0.063 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function SLATT_4 PF18186.1 OEU15885.1 - 2.1 8.0 3.7 8.4 6.0 0.9 2.6 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 PI3_PI4_kinase PF00454.27 OEU15888.1 - 5.4e-22 78.8 0.0 7.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-CCCH_6 PF18585.1 OEU15888.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Proteasome PF00227.26 OEU15888.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Proteasome subunit APH PF01636.23 OEU15888.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.22 OEU15890.1 - 1.2e-12 47.4 0.0 1.2e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Podoplanin PF05808.11 OEU15892.1 - 6.1 6.9 8.9 0.78 9.8 2.3 2.3 2 0 0 2 2 2 0 Podoplanin DNA_ligase_aden PF01653.18 OEU15893.1 - 1.1e-34 120.0 4.3 7.8e-17 61.3 2.3 3.7 1 1 1 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 OEU15893.1 - 1e-22 79.8 1.0 4.2e-22 77.8 0.6 2.1 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain BRCT PF00533.26 OEU15893.1 - 6.5e-10 39.3 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_2 PF12826.7 OEU15893.1 - 1.1e-06 28.7 0.0 4.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 OEU15893.1 - 0.0018 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Lar_restr_allev PF14354.6 OEU15893.1 - 0.16 12.4 0.5 0.37 11.2 0.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar DNA_ligase_ZBD PF03119.16 OEU15893.1 - 0.16 12.0 2.3 0.48 10.5 2.3 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF4829 PF16111.5 OEU15893.1 - 0.55 11.0 3.1 3.1 8.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4829) SIR2 PF02146.17 OEU15894.1 - 2.3e-33 115.6 0.1 2.8e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OEU15894.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf_UBZ PF18439.1 OEU15894.1 - 0.6 9.8 4.3 5.1 6.8 0.9 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 OEU15895.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15895.1 - 0.0034 16.7 0.0 0.027 13.8 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase SBF PF01758.16 OEU15896.1 - 1e-18 67.7 5.8 1e-18 67.7 5.8 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3845 PF12956.7 OEU15896.1 - 0.11 11.9 0.3 0.18 11.2 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure EGF PF00008.27 OEU15897.1 - 1.3e-09 38.2 67.2 0.0023 18.2 1.0 9.3 7 3 0 7 7 7 6 EGF-like domain EGF_2 PF07974.13 OEU15897.1 - 0.044 14.2 77.1 0.14 12.5 9.8 8.2 7 3 0 7 7 7 0 EGF-like domain Tub_N PF16322.5 OEU15897.1 - 0.066 13.6 0.5 0.16 12.4 0.5 1.7 1 0 0 1 1 1 0 Tubby N-terminal ABC2_membrane_3 PF12698.7 OEU15898.1 - 0.02 14.0 1.0 0.52 9.4 0.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2834 PF11196.8 OEU15899.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) TPT PF03151.16 OEU15900.1 - 3.7e-61 207.0 8.9 4.3e-61 206.8 8.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU15900.1 - 2.8e-05 24.3 19.7 0.00012 22.3 9.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family TIM PF00121.18 OEU15901.1 - 1.6e-18 67.0 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase HSF_DNA-bind PF00447.17 OEU15902.1 - 3e-16 59.8 0.2 3.5e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 OEU15903.1 - 7.7e-61 205.8 0.0 9.1e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15903.1 - 1.5e-25 90.0 0.0 1.8e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU15903.1 - 4.9e-07 29.3 0.0 8.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU15903.1 - 7.5e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OEU15903.1 - 0.023 13.5 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1284 PF06935.11 OEU15903.1 - 0.1 13.0 3.6 0.33 11.4 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1284) EF-hand_1 PF00036.32 OEU15904.1 - 0.11 12.1 0.0 0.43 10.2 0.0 2.1 1 0 0 1 1 1 0 EF hand La_HTH_kDCL PF18177.1 OEU15904.1 - 0.16 12.3 0.1 0.5 10.7 0.1 1.9 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain TFIIA PF03153.13 OEU15905.1 - 0.009 16.0 34.2 0.014 15.4 34.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3807 PF12720.7 OEU15905.1 - 2.1 8.6 31.3 0.29 11.4 6.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Cofac_haem_bdg PF04187.13 OEU15906.1 - 9.2e-45 153.2 0.0 1.7e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN VbhA PF18495.1 OEU15906.1 - 0.068 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Antitoxin VbhA LRR_6 PF13516.6 OEU15908.1 - 3e-14 51.8 8.3 0.0013 18.7 0.0 7.3 7 0 0 7 7 7 4 Leucine Rich repeat INSIG PF07281.12 OEU15908.1 - 0.04 13.6 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) SDA1 PF05285.12 OEU15908.1 - 0.52 9.7 12.4 0.018 14.5 6.8 1.4 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 OEU15908.1 - 6.3 5.0 10.4 9.4 4.4 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein LCM PF04072.14 OEU15909.1 - 2.2e-10 40.8 0.0 7.4e-08 32.5 0.0 2.4 1 1 1 2 2 2 2 Leucine carboxyl methyltransferase Neurokinin_B PF03823.14 OEU15909.1 - 0.29 11.2 2.1 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Neurokinin B Sulfotransfer_2 PF03567.14 OEU15910.1 - 0.00087 19.3 3.0 0.0021 18.0 2.2 2.1 1 1 1 2 2 2 1 Sulfotransferase family DUF3914 PF13053.6 OEU15910.1 - 0.42 11.0 2.4 1.7 9.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) HHV-5_US34A PF17087.5 OEU15911.1 - 0.12 12.5 0.3 0.18 12.0 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus US34A protein family Peptidase_S49_N PF08496.10 OEU15911.1 - 0.14 12.2 2.0 0.16 12.0 2.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMEM154 PF15102.6 OEU15912.1 - 0.02 14.8 0.3 0.02 14.8 0.3 2.0 2 0 0 2 2 2 0 TMEM154 protein family FAM176 PF14851.6 OEU15912.1 - 0.077 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Saf_2TM PF18303.1 OEU15912.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Chloroa_b-bind PF00504.21 OEU15913.1 - 5.3e-21 75.8 0.0 6.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein AFG1_ATPase PF03969.16 OEU15914.1 - 1e-78 264.8 0.8 2.3e-71 240.6 0.2 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OEU15914.1 - 0.0022 18.4 0.2 0.028 14.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OEU15914.1 - 0.029 14.4 0.0 0.19 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU15914.1 - 0.072 13.4 0.1 0.25 11.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain cNMP_binding PF00027.29 OEU15915.1 - 6.6e-13 48.5 0.0 1.5e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Bestrophin PF01062.21 OEU15915.1 - 6.1e-05 22.5 0.0 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Rhodanese PF00581.20 OEU15918.1 - 1.3e-08 35.3 0.1 0.0089 16.5 0.0 4.3 2 2 1 3 3 3 3 Rhodanese-like domain Tmemb_9 PF05434.11 OEU15918.1 - 0.12 12.3 1.3 7 6.5 0.1 2.6 2 0 0 2 2 2 0 TMEM9 Cry1Ac_D5 PF17997.1 OEU15919.1 - 0.057 13.3 0.9 0.066 13.1 0.2 1.4 2 0 0 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 EF-hand_5 PF13202.6 OEU15921.1 - 0.00012 21.4 0.2 0.00029 20.2 0.2 1.6 1 0 0 1 1 1 1 EF hand Pkinase_fungal PF17667.1 OEU15921.1 - 0.00048 19.0 0.5 0.00075 18.4 0.5 1.2 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_1 PF00036.32 OEU15921.1 - 0.0029 17.1 0.0 0.0073 15.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OEU15921.1 - 0.019 14.8 0.1 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 OEU15921.1 - 0.089 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Sod_Cu PF00080.20 OEU15923.1 - 0.00013 22.1 7.4 0.00045 20.4 0.9 2.6 2 1 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) NPR3 PF03666.13 OEU15925.1 - 0.69 8.6 3.9 0.76 8.5 3.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC27 PF09507.10 OEU15925.1 - 1.7 7.9 12.7 2.2 7.6 12.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 OEU15925.1 - 2.5 6.3 11.1 3 6.0 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UspA1_rep PF18792.1 OEU15926.1 - 2.8e-13 49.1 69.9 0.016 15.7 1.5 10.6 11 0 0 11 11 11 7 Ubiquitous surface protein adhesin repeat YadA_head PF05658.14 OEU15926.1 - 0.00033 20.9 1.8 0.048 14.1 0.1 6.4 6 2 2 8 8 8 3 Head domain of trimeric autotransporter adhesin Dynactin_p22 PF07426.11 OEU15926.1 - 0.02 14.7 3.4 0.032 14.1 3.4 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 NAD_binding_2 PF03446.15 OEU15926.1 - 1.3 9.2 18.4 2.4 8.3 0.4 4.6 1 1 4 5 5 5 0 NAD binding domain of 6-phosphogluconate dehydrogenase SAP PF02037.27 OEU15927.1 - 4.1e-10 39.2 1.8 7.9e-10 38.3 1.8 1.5 1 0 0 1 1 1 1 SAP domain GGACT PF06094.12 OEU15928.1 - 1e-06 29.4 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OEU15928.1 - 3.9e-06 27.2 0.0 6.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family zf-C3HC4 PF00097.25 OEU15929.1 - 5.3e-06 26.2 10.4 1.1e-05 25.1 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 OEU15929.1 - 5.6e-05 23.4 0.0 0.23 11.9 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-RING_UBOX PF13445.6 OEU15929.1 - 0.00016 21.6 8.6 0.00038 20.4 8.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU15929.1 - 0.00025 21.1 9.2 0.00049 20.2 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OEU15929.1 - 0.00025 21.3 10.3 0.00051 20.3 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU15929.1 - 0.00038 20.2 10.0 0.00084 19.1 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_2 PF16589.5 OEU15929.1 - 0.0038 17.6 1.6 1.6 9.2 0.0 3.7 3 1 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_5 PF14634.6 OEU15929.1 - 0.0046 16.9 11.0 0.0091 15.9 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU15929.1 - 0.0073 16.1 13.1 0.013 15.4 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OEU15929.1 - 0.037 13.9 4.7 0.094 12.5 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 OEU15929.1 - 0.32 11.3 6.0 0.98 9.8 6.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OEU15929.1 - 6.4 6.6 7.3 14 5.5 7.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF393 PF04134.12 OEU15930.1 - 5e-16 60.1 0.0 8.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF4113 PF13438.6 OEU15930.1 - 0.09 12.9 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Pribosyltran PF00156.27 OEU15931.1 - 5.7e-15 55.2 0.1 8.6e-15 54.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NIBRIN_BRCT_II PF16508.5 OEU15932.1 - 0.078 13.3 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF4611 PF15387.6 OEU15932.1 - 2 8.7 5.3 5.1 7.4 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Beta-lactamase PF00144.24 OEU15933.1 - 4.2e-47 161.0 0.0 8.5e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase ABC1 PF03109.16 OEU15933.1 - 1.2e-26 93.2 0.1 9.4e-26 90.3 0.1 2.4 2 0 0 2 2 2 1 ABC1 family Voldacs PF03517.13 OEU15933.1 - 0.19 11.8 3.4 0.38 10.9 3.4 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF4820 PF16091.5 OEU15933.1 - 0.54 9.6 4.1 1.1 8.5 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 OEU15933.1 - 0.96 9.1 3.2 2.2 8.0 3.2 1.5 1 0 0 1 1 1 0 FAM176 family Caldesmon PF02029.15 OEU15934.1 - 0.096 11.4 18.5 0.13 11.0 18.5 1.1 1 0 0 1 1 1 0 Caldesmon TFIIA PF03153.13 OEU15934.1 - 0.13 12.2 25.4 0.17 11.8 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1840 PF08895.11 OEU15934.1 - 0.2 12.0 7.5 8.1 6.8 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) YfhO PF09586.10 OEU15934.1 - 2.7 6.1 5.7 3.2 5.9 5.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Membralin PF09746.9 OEU15934.1 - 8.6 5.3 9.4 11 4.9 9.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein WW PF00397.26 OEU15935.1 - 0.00019 21.5 0.1 0.00032 20.7 0.1 1.4 1 0 0 1 1 1 1 WW domain Cyt-b5 PF00173.28 OEU15936.1 - 2.1e-07 31.0 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OEU15936.1 - 0.00017 21.7 0.0 0.00047 20.3 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 OEU15936.1 - 0.00038 21.1 0.0 0.00088 19.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain OCRE PF17780.1 OEU15936.1 - 0.04 13.9 0.1 0.098 12.7 0.1 1.6 1 0 0 1 1 1 0 OCRE domain F-box-like PF12937.7 OEU15936.1 - 1.4 8.9 4.1 2.7 7.9 4.1 1.5 1 0 0 1 1 1 0 F-box-like DNA_methylase PF00145.17 OEU15938.1 - 8.2e-34 117.4 0.3 5.7e-33 114.7 0.0 2.0 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 OEU15938.1 - 0.0055 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Epimerase PF01370.21 OEU15939.1 - 2.4e-13 50.1 0.1 4.8e-13 49.1 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OEU15939.1 - 4.5e-13 49.5 0.4 2.3e-12 47.2 0.4 2.0 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OEU15939.1 - 8.5e-09 35.2 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU15939.1 - 4.9e-07 29.0 0.2 8.5e-07 28.3 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OEU15939.1 - 3.4e-05 23.4 0.1 4.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 OEU15939.1 - 3.8e-05 23.4 0.4 6.4e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OEU15939.1 - 0.00013 21.1 0.1 0.00021 20.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 OEU15939.1 - 0.0014 18.9 0.1 0.0025 18.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 OEU15939.1 - 0.0025 18.0 0.1 0.0048 17.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RELT PF12606.8 OEU15939.1 - 0.0082 15.1 0.2 0.0082 15.1 0.2 1.6 2 0 0 2 2 2 1 Tumour necrosis factor receptor superfamily member 19 NAD_binding_4 PF07993.12 OEU15939.1 - 0.016 14.4 0.6 0.37 9.9 0.6 2.4 1 1 0 1 1 1 0 Male sterility protein KR PF08659.10 OEU15939.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 OEU15939.1 - 0.026 14.8 0.3 0.052 13.8 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 OEU15939.1 - 0.035 14.7 0.2 0.072 13.7 0.2 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 OEU15940.1 - 1.4e-12 47.5 0.1 1.8e-07 30.8 0.0 2.9 2 1 0 2 2 2 2 ThiF family Piezo_RRas_bdg PF12166.8 OEU15940.1 - 0.01 15.1 0.3 0.013 14.9 0.3 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain rRNA_processing PF08524.11 OEU15940.1 - 2.2 8.3 4.6 11 6.1 0.2 2.0 1 1 1 2 2 2 0 rRNA processing PBP1_TM PF14812.6 OEU15940.1 - 6.8 7.1 7.8 5 7.6 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PhyH PF05721.13 OEU15943.1 - 0.0037 17.5 0.0 0.087 13.1 0.0 2.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3439 PF11921.8 OEU15943.1 - 0.36 10.8 5.5 0.96 9.4 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CRAL_TRIO_N PF03765.15 OEU15944.1 - 0.15 12.3 0.1 0.47 10.7 0.1 1.9 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain 7tm_1 PF00001.21 OEU15945.1 - 0.065 12.6 2.9 1.8 7.8 0.2 2.3 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Rgp1 PF08737.10 OEU15945.1 - 0.16 11.1 17.1 0.028 13.6 10.3 2.6 2 0 0 2 2 2 0 Rgp1 CLZ PF16526.5 OEU15945.1 - 0.23 11.8 3.3 0.95 9.9 3.3 2.0 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tetraspanin PF00335.20 OEU15945.1 - 0.63 9.7 5.6 1.1 8.9 5.6 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF1151 PF06625.11 OEU15945.1 - 1.1 9.3 14.1 0.29 11.1 6.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) DUF948 PF06103.11 OEU15946.1 - 0.12 12.7 4.7 0.85 9.9 0.3 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FBPase_glpX PF03320.13 OEU15946.1 - 0.13 11.1 0.3 0.27 10.1 0.1 1.5 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded TauD PF02668.16 OEU15947.1 - 0.0037 17.1 0.1 0.0044 16.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.25 OEU15948.1 - 1.1e-23 83.7 0.4 3.5e-19 69.0 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU15948.1 - 2.1e-16 60.2 0.0 1e-11 44.9 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU15948.1 - 9.4e-09 35.4 0.1 1.5e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU15948.1 - 0.00066 19.2 0.0 0.0058 16.1 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OEU15948.1 - 0.0034 16.6 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OEU15948.1 - 0.058 12.5 0.0 0.18 11.0 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 OEU15948.1 - 0.22 10.6 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NLPC_P60 PF00877.19 OEU15950.1 - 0.088 12.8 0.2 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 NlpC/P60 family DUF4995 PF16386.5 OEU15951.1 - 0.11 12.5 0.3 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function SPX PF03105.19 OEU15951.1 - 0.13 12.2 0.0 0.13 12.2 0.0 5.3 1 1 0 3 3 3 0 SPX domain adh_short_C2 PF13561.6 OEU15953.1 - 1e-44 152.8 0.0 1.3e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU15953.1 - 1.8e-40 138.5 0.0 2.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU15953.1 - 2.4e-08 34.1 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OEU15953.1 - 0.0056 17.2 0.2 0.015 15.9 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OEU15953.1 - 0.017 15.0 0.3 0.034 14.0 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OEU15953.1 - 0.19 11.8 0.5 0.39 10.8 0.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_11 PF08241.12 OEU15954.1 - 1.6e-11 44.7 0.0 2.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU15954.1 - 4.7e-07 29.7 0.0 6.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU15954.1 - 6e-07 29.0 0.0 8.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OEU15954.1 - 9.6e-07 29.4 0.0 1.8e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU15954.1 - 7.4e-06 26.6 0.0 1.1e-05 26.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU15954.1 - 9.1e-06 25.6 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OEU15954.1 - 6.5e-05 21.7 0.0 9e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 OEU15954.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.3 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 OEU15954.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 OEU15954.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Peptidase_C101 PF16218.5 OEU15955.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C101 Zip PF02535.22 OEU15955.1 - 0.014 14.6 0.0 0.037 13.3 0.0 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter EMP70 PF02990.16 OEU15955.1 - 0.04 12.6 4.3 0.11 11.2 4.3 1.6 1 0 0 1 1 1 0 Endomembrane protein 70 OAD_gamma PF04277.13 OEU15955.1 - 0.055 14.1 1.3 0.24 12.0 0.1 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Reprolysin_3 PF13582.6 OEU15956.1 - 3.5 8.2 8.4 26 5.3 0.0 4.3 4 0 0 4 4 4 0 Metallo-peptidase family M12B Reprolysin-like 2OG-FeII_Oxy_3 PF13640.6 OEU15957.1 - 3e-11 44.0 0.0 5.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EamA PF00892.20 OEU15959.1 - 4.3e-25 88.5 18.2 6.9e-15 55.4 3.8 2.7 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU15959.1 - 1.1e-08 34.8 3.5 0.00017 21.0 0.7 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 OEU15959.1 - 1.3e-05 24.6 5.6 1.3e-05 24.6 5.6 1.8 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport Nrap_D5 PF17406.2 OEU15959.1 - 0.027 14.2 0.3 0.047 13.4 0.3 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Response_reg PF00072.24 OEU15960.1 - 4.7e-09 36.4 0.0 2.1e-08 34.3 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OEU15960.1 - 8.9e-08 32.6 0.0 2.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OEU15960.1 - 0.00047 20.1 2.0 0.0021 18.1 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Imm48 PF15574.6 OEU15961.1 - 0.073 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 48 PMSR PF01625.21 OEU15962.1 - 3e-44 150.9 0.1 3.7e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TPMT PF05724.11 OEU15963.1 - 1.9e-09 37.5 0.0 1.3e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OEU15963.1 - 0.00028 21.5 0.0 0.89 10.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OEU15963.1 - 0.00035 21.2 0.0 0.0082 16.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU15963.1 - 0.01 16.6 0.1 0.02 15.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OEU15963.1 - 0.031 14.1 0.0 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 OEU15963.1 - 0.033 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 OEU15964.1 - 3.6e-07 30.1 0.0 6.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 OEU15964.1 - 0.00046 20.2 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 OEU15964.1 - 0.011 15.3 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Nitroreductase PF00881.24 OEU15965.1 - 2e-21 76.8 0.0 2.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OEU15965.1 - 0.00053 19.6 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase EF-hand_7 PF13499.6 OEU15965.1 - 0.00092 19.6 0.1 0.0029 18.0 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OEU15965.1 - 0.012 15.5 0.3 0.028 14.3 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair NAD_binding_10 PF13460.6 OEU15966.1 - 9.9e-22 77.7 0.0 1.2e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OEU15966.1 - 0.0024 16.9 0.0 0.0052 15.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OEU15966.1 - 0.0061 16.1 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OEU15966.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 OEU15966.1 - 0.045 14.2 0.1 0.11 12.9 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OEU15966.1 - 0.061 13.6 0.1 0.093 13.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OEU15966.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family MPP6 PF10175.9 OEU15967.1 - 0.002 18.6 0.7 0.1 13.1 0.1 2.3 2 0 0 2 2 2 1 M-phase phosphoprotein 6 TPR_7 PF13176.6 OEU15967.1 - 0.0035 17.3 0.4 0.3 11.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU15967.1 - 0.011 15.5 0.2 3.9 7.4 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU15967.1 - 0.037 14.2 0.1 0.92 9.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3408 PF11888.8 OEU15967.1 - 0.098 12.8 5.2 0.47 10.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TPR_12 PF13424.6 OEU15967.1 - 0.11 12.8 3.9 5.1 7.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Roughex PF06020.11 OEU15967.1 - 6.6 5.7 10.2 9.9 5.1 3.9 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Gti1_Pac2 PF09729.9 OEU15967.1 - 8.5 6.4 11.2 21 5.2 11.2 1.7 1 1 0 1 1 1 0 Gti1/Pac2 family RRM_1 PF00076.22 OEU15968.1 - 7.8e-06 25.6 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytomega_UL84 PF06284.11 OEU15968.1 - 0.65 8.4 9.2 0.91 7.9 9.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Dicty_REP PF05086.12 OEU15968.1 - 2.4 6.0 4.8 3.1 5.7 4.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MCM_bind PF09739.9 OEU15968.1 - 2.6 6.4 6.3 3.4 6.0 6.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Vfa1 PF08432.10 OEU15968.1 - 4.1 7.7 10.6 6.7 7.0 10.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 E1_dh PF00676.20 OEU15969.1 - 4.6e-97 324.6 0.6 5.3e-97 324.4 0.6 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OEU15969.1 - 9.5e-05 22.2 3.4 0.00012 21.9 1.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OEU15969.1 - 0.0047 16.2 1.0 0.008 15.4 0.1 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DEK_C PF08766.11 OEU15969.1 - 0.015 15.2 0.3 0.026 14.4 0.3 1.3 1 0 0 1 1 1 0 DEK C terminal domain DEDD_Tnp_IS110 PF01548.17 OEU15970.1 - 0.0075 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Transposase TssO PF17561.2 OEU15970.1 - 0.024 14.7 0.1 0.042 14.0 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF908 PF06012.12 OEU15970.1 - 0.53 9.6 8.1 0.72 9.2 8.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Orf78 PF06024.12 OEU15970.1 - 0.59 10.5 5.7 2.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Orf78 (ac78) DUF2615 PF11027.8 OEU15970.1 - 0.99 9.6 10.5 0.2 11.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Conotoxin PF02950.17 OEU15970.1 - 1.7 9.7 6.6 0.57 11.2 0.3 2.6 2 1 1 3 3 3 0 Conotoxin MAP65_ASE1 PF03999.12 OEU15970.1 - 2 7.0 11.2 2.2 6.9 11.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) CLN3 PF02487.17 OEU15970.1 - 7.2 5.5 5.6 0.66 8.9 0.5 1.7 1 1 1 2 2 2 0 CLN3 protein DUF4834 PF16118.5 OEU15970.1 - 9.1 7.3 10.4 14 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Elf1 PF05129.13 OEU15972.1 - 5.6e-25 87.2 0.7 6e-25 87.1 0.7 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 OEU15972.1 - 0.0046 17.3 1.2 0.0068 16.8 1.2 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.15 OEU15972.1 - 0.0079 16.2 1.6 1.1 9.4 0.4 2.3 1 1 1 2 2 2 2 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.7 OEU15972.1 - 0.021 14.8 2.0 0.042 13.8 2.0 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain CcmH PF03918.14 OEU15972.1 - 0.036 13.3 0.5 0.04 13.2 0.5 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein zf-C2H2_4 PF13894.6 OEU15972.1 - 0.17 12.8 3.0 12 7.0 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CTP_transf_1 PF01148.20 OEU15973.1 - 1.1e-46 159.8 5.7 1.2e-46 159.6 5.7 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family ECF-ribofla_trS PF07155.12 OEU15973.1 - 1.9 8.5 7.2 2 8.4 2.9 2.1 1 1 1 2 2 2 0 ECF-type riboflavin transporter, S component ATP-sulfurylase PF01747.17 OEU15974.1 - 9.5e-70 234.4 0.0 1.2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 OEU15974.1 - 1.6e-34 118.8 0.0 2.6e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain TssD PF17642.1 OEU15975.1 - 0.027 14.3 0.0 0.074 12.9 0.0 1.8 2 0 0 2 2 2 0 Hemolysin coregulated protein Hcp (TssD) Auto_anti-p27 PF06677.12 OEU15975.1 - 0.035 14.3 0.5 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-LITAF-like PF10601.9 OEU15975.1 - 0.16 12.2 1.6 12 6.2 0.0 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.6 OEU15975.1 - 0.36 10.3 3.0 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 OEU15975.1 - 1 9.5 4.6 26 5.0 4.6 2.6 1 1 0 1 1 1 0 Zinc-binding RING-finger AFP PF02420.15 OEU15975.1 - 4.9 7.8 7.3 4.9 7.8 1.2 2.7 2 0 0 2 2 2 0 Insect antifreeze protein repeat Ras PF00071.22 OEU15976.1 - 1.1e-24 86.8 0.1 1.2e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU15976.1 - 1.6e-24 86.4 0.0 1.7e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU15976.1 - 5.8e-06 25.9 0.0 6.1e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OEU15976.1 - 0.00014 21.3 0.0 0.00014 21.3 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OEU15976.1 - 0.016 14.6 0.0 0.018 14.5 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OEU15976.1 - 0.02 14.5 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OEU15976.1 - 0.05 13.7 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase CPT PF07931.12 OEU15976.1 - 0.067 13.0 0.0 0.072 12.9 0.0 1.0 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 OEU15976.1 - 0.099 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region GRDP-like PF07173.12 OEU15977.1 - 1.7e-18 67.6 7.6 6.6e-15 56.0 0.5 3.7 3 1 1 4 4 4 2 Glycine-rich domain-containing protein-like Apocytochr_F_C PF01333.19 OEU15977.1 - 0.071 13.2 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Apocytochrome F, C-terminal DUF4191 PF13829.6 OEU15977.1 - 0.21 10.9 0.4 0.34 10.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) TPR_2 PF07719.17 OEU15978.1 - 0.021 14.9 0.0 0.6 10.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU15978.1 - 0.087 13.1 0.0 2.6 8.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat CbtA PF09490.10 OEU15978.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TPR_7 PF13176.6 OEU15978.1 - 0.59 10.3 2.7 34 4.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 OEU15979.1 - 3.9e-12 46.1 0.0 8.1e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU15979.1 - 5.3e-10 39.0 0.1 2.8e-09 36.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 OEU15979.1 - 0.078 12.5 0.1 0.32 10.6 0.1 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF4806 PF16064.5 OEU15982.1 - 0.038 14.3 1.1 0.063 13.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) TUDOR_5 PF18359.1 OEU15986.1 - 0.037 13.7 0.5 0.09 12.5 0.5 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 LBR_tudor PF09465.10 OEU15986.1 - 0.037 13.8 1.0 0.088 12.6 1.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 OEU15986.1 - 0.059 13.4 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) MgrB PF13998.6 OEU15986.1 - 0.18 11.7 0.2 0.63 10.0 0.2 2.0 1 0 0 1 1 1 0 MgrB protein Agenet PF05641.12 OEU15986.1 - 0.18 12.3 2.1 0.51 10.8 0.6 2.5 2 0 0 2 2 2 0 Agenet domain Tudor_2 PF18104.1 OEU15986.1 - 0.23 11.2 3.3 0.41 10.4 0.2 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Clr2_transil PF16761.5 OEU15986.1 - 0.41 11.5 3.3 36 5.3 0.1 3.9 3 0 0 3 3 3 0 Transcription-silencing protein, cryptic loci regulator Clr2 Macoilin PF09726.9 OEU15987.1 - 0.053 12.1 19.4 0.066 11.8 19.4 1.0 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 OEU15987.1 - 1 9.2 30.8 1.3 8.8 30.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-MYND PF01753.18 OEU15988.1 - 5.6e-08 32.7 6.6 5.6e-08 32.7 6.6 2.7 3 0 0 3 3 3 1 MYND finger LRR_6 PF13516.6 OEU15988.1 - 0.11 12.6 0.2 4.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat zf-Mss51 PF13824.6 OEU15988.1 - 0.4 10.8 2.9 1.7 8.8 2.9 2.2 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Mit_KHE1 PF10173.9 OEU15990.1 - 5.9 6.9 9.5 7.9 6.5 6.3 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related TraI PF07057.11 OEU15991.1 - 0.063 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 DNA helicase TraI SNARE PF05739.19 OEU15991.1 - 0.38 10.8 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 SNARE domain ADIP PF11559.8 OEU15991.1 - 1.2 9.3 9.8 0.38 10.8 5.0 2.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.10 OEU15991.1 - 5.3 7.4 13.1 12 6.3 13.1 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ATP-grasp_4 PF13535.6 OEU15992.1 - 2.1e-12 46.9 0.0 5.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OEU15992.1 - 1e-09 38.4 0.4 9.8e-09 35.3 0.0 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 OEU15992.1 - 1.6e-09 38.1 0.2 4e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OEU15992.1 - 0.00018 21.1 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain LAL_C2 PF18603.1 OEU15992.1 - 0.00025 21.2 0.0 0.00072 19.7 0.0 1.9 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 OEU15992.1 - 0.096 12.4 0.4 1.3 8.8 0.1 2.5 2 1 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Atracotoxin PF05353.11 OEU15994.1 - 0.15 12.2 4.4 0.27 11.3 4.4 1.5 1 0 0 1 1 1 0 Delta Atracotoxin Toxin_12 PF07740.12 OEU15994.1 - 0.15 12.8 7.2 0.24 12.1 7.2 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Toxin_22 PF08092.11 OEU15994.1 - 0.16 12.0 4.6 0.3 11.2 4.6 1.5 1 0 0 1 1 1 0 Magi peptide toxin family Conotoxin PF02950.17 OEU15994.1 - 0.81 10.8 8.9 0.66 11.0 4.2 2.2 2 0 0 2 2 2 0 Conotoxin Chloroa_b-bind PF00504.21 OEU15995.1 - 9.9e-30 104.2 0.0 1.4e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HA2 PF04408.23 OEU15996.1 - 3.7e-16 59.3 0.2 8e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OEU15996.1 - 1.7e-15 57.1 0.0 3.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OEU15996.1 - 1.2e-12 48.1 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU15996.1 - 4.9e-10 39.5 0.1 1.3e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OEU15996.1 - 0.00013 22.3 1.8 0.00052 20.4 0.1 2.7 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 OEU15996.1 - 0.0032 16.9 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.6 OEU15996.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OEU15996.1 - 0.078 12.0 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 OEU15996.1 - 0.085 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OEU15996.1 - 0.091 12.7 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 OEU15996.1 - 0.11 12.8 0.1 0.37 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.6 OEU15997.1 - 0.00017 21.4 0.1 0.067 13.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 OEU15997.1 - 0.0022 17.6 0.6 0.46 10.0 0.3 2.2 1 1 1 2 2 2 2 Methyltransferase small domain TIP_N PF12457.8 OEU15997.1 - 0.0075 16.6 1.8 0.17 12.3 0.0 2.3 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal UPF0020 PF01170.18 OEU15997.1 - 0.043 13.5 0.4 1.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Tachylectin PF14517.6 OEU15997.1 - 0.047 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Tachylectin CheR PF01739.18 OEU15997.1 - 0.07 12.6 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Striatin PF08232.12 OEU15998.1 - 0.56 10.8 11.2 0.67 10.5 11.2 1.2 1 0 0 1 1 1 0 Striatin family CRCB PF02537.15 OEU15999.1 - 9.9e-30 102.7 13.3 1.2e-15 57.5 2.4 2.8 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CBM46 PF18448.1 OEU15999.1 - 0.016 15.5 0.6 0.041 14.2 0.6 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain LAMTOR5 PF16672.5 OEU15999.1 - 0.082 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Pyr_redox_2 PF07992.14 OEU16000.1 - 4.6e-54 183.7 0.0 6.9e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU16000.1 - 1.6e-26 92.7 0.0 3.3e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU16000.1 - 1.4e-17 64.0 1.9 4.2e-14 52.9 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU16000.1 - 1.5e-08 34.3 0.1 8.6e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU16000.1 - 4e-06 26.2 2.9 0.00027 20.2 2.9 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 OEU16000.1 - 3.2e-05 23.5 0.9 6.8e-05 22.4 0.6 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OEU16000.1 - 3.4e-05 23.1 0.9 6.4e-05 22.2 0.9 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OEU16000.1 - 0.0002 20.2 1.0 0.0084 14.8 0.6 2.9 4 0 0 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OEU16000.1 - 0.00048 19.5 0.0 0.0015 17.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF971 PF06155.12 OEU16000.1 - 0.017 15.7 0.0 0.052 14.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DAO PF01266.24 OEU16000.1 - 0.035 13.7 1.3 0.064 12.8 0.6 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OEU16000.1 - 0.049 12.9 0.9 0.093 12.0 0.9 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 OEU16000.1 - 9.7 6.5 6.3 2 8.7 1.8 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU16001.1 - 4.2e-54 183.8 0.0 6.3e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU16001.1 - 1.5e-26 92.8 0.0 3.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU16001.1 - 1.3e-17 64.1 1.9 4.1e-14 52.9 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU16001.1 - 2.5e-08 33.5 0.2 8e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU16001.1 - 4.9e-06 25.9 3.3 0.00026 20.2 2.9 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 OEU16001.1 - 2.9e-05 23.6 0.8 6.2e-05 22.5 0.6 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OEU16001.1 - 3.6e-05 23.0 1.1 7.4e-05 22.0 1.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OEU16001.1 - 0.00018 20.3 1.0 0.0081 14.9 0.6 2.9 4 0 0 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OEU16001.1 - 0.0005 19.4 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF971 PF06155.12 OEU16001.1 - 0.017 15.8 0.0 0.05 14.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DAO PF01266.24 OEU16001.1 - 0.031 13.9 1.2 0.062 12.9 0.6 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OEU16001.1 - 0.041 13.1 0.5 0.082 12.1 0.5 1.4 1 0 0 1 1 1 0 Thi4 family Oxidored_q6 PF01058.22 OEU16002.1 - 4.7e-23 81.4 0.1 7e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ALAD PF00490.21 OEU16003.1 - 6.4e-141 469.1 0.0 7.6e-141 468.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Amino_oxidase PF01593.24 OEU16004.1 - 4e-15 56.1 0.0 6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU16004.1 - 3.7e-14 52.7 0.0 7.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU16004.1 - 7.4e-13 48.8 3.0 3.9e-06 26.7 0.5 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU16004.1 - 1.3e-10 41.0 0.3 1.2e-06 27.9 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OEU16004.1 - 2.8e-07 30.0 0.5 2.4e-06 27.0 0.2 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OEU16004.1 - 8e-07 28.1 0.1 0.002 16.9 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 OEU16004.1 - 6e-06 25.7 0.1 8.9e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU16004.1 - 3.9e-05 23.0 0.2 6.9e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU16004.1 - 0.00055 20.4 1.1 0.025 15.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU16004.1 - 0.0019 17.6 0.5 0.0084 15.5 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 OEU16004.1 - 0.0037 15.9 0.3 0.11 11.0 0.1 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 OEU16004.1 - 0.0058 15.9 0.1 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OEU16004.1 - 0.053 12.3 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 MCRA family GMC_oxred_N PF00732.19 OEU16004.1 - 0.054 12.9 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase GIDA PF01134.22 OEU16004.1 - 0.059 12.4 0.8 0.15 11.1 0.8 1.7 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OEU16004.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.22 OEU16005.1 - 3.4e-75 253.5 0.0 4.9e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_1c PF00749.21 OEU16006.1 - 1.6e-95 319.6 0.0 2.4e-95 319.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_bind PF01588.20 OEU16006.1 - 8.8e-27 93.1 0.0 1.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GlutR_N PF05201.15 OEU16007.1 - 3e-39 134.1 0.0 6.7e-39 133.0 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 OEU16007.1 - 6.2e-37 126.7 0.5 6e-36 123.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 OEU16007.1 - 5.5e-23 81.2 3.2 5.5e-23 81.2 3.2 2.0 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 OEU16007.1 - 2.6e-06 26.6 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OEU16007.1 - 0.0003 21.3 0.1 0.0022 18.6 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent VirB8 PF04335.13 OEU16007.1 - 0.0018 18.2 0.1 0.0042 16.9 0.1 1.6 1 0 0 1 1 1 1 VirB8 protein NAD_binding_2 PF03446.15 OEU16007.1 - 0.0077 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OEU16007.1 - 0.073 12.9 0.8 0.32 10.9 0.0 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OEU16007.1 - 0.077 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Chloroa_b-bind PF00504.21 OEU16008.1 - 7.3e-42 143.6 0.2 7.2e-41 140.4 0.0 2.5 2 1 0 2 2 2 1 Chlorophyll A-B binding protein PEPCK_ATP PF01293.20 OEU16009.1 - 9.9e-207 687.2 0.0 1.2e-206 686.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 OEU16009.1 - 0.14 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain CPSase_L_D2 PF02786.17 OEU16010.1 - 1.6e-75 253.3 0.2 3.1e-75 252.3 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OEU16010.1 - 1.3e-65 220.8 0.0 2.1e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OEU16010.1 - 4.5e-35 120.5 0.1 8.8e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OEU16010.1 - 8.6e-35 119.1 0.0 1.9e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OEU16010.1 - 3.8e-27 95.5 0.0 9.2e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OEU16010.1 - 1.2e-18 66.7 6.2 3.1e-18 65.4 6.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OEU16010.1 - 4.6e-10 39.4 0.0 9.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OEU16010.1 - 3.2e-09 36.6 0.1 6.7e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OEU16010.1 - 3.6e-05 23.9 0.1 8.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OEU16010.1 - 7.3e-05 22.5 0.1 0.00018 21.2 0.1 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OEU16010.1 - 0.00042 20.1 6.6 0.0046 16.8 0.3 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like DUF2118 PF09891.9 OEU16010.1 - 0.012 15.5 0.9 0.029 14.3 0.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.6 OEU16010.1 - 0.019 15.7 0.6 0.19 12.4 0.3 2.9 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_D23 PF16576.5 OEU16010.1 - 0.024 13.9 1.1 2.9 7.1 0.1 3.2 3 1 1 4 4 4 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_Ter PF15632.6 OEU16010.1 - 0.042 13.6 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 OEU16010.1 - 0.094 12.0 0.0 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 OEU16010.1 - 0.11 12.4 0.5 0.25 11.3 0.5 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein TTL PF03133.15 OEU16010.1 - 0.12 11.5 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family RnfC_N PF13375.6 OEU16010.1 - 0.15 12.0 0.9 0.39 10.7 0.9 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 OEU16010.1 - 0.35 10.5 2.0 1.1 8.9 0.3 2.5 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Chloroa_b-bind PF00504.21 OEU16011.1 - 4.5e-33 115.1 0.0 6.6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PGI PF00342.19 OEU16012.1 - 9.9e-40 136.5 0.0 1e-36 126.6 0.0 3.2 2 1 0 2 2 2 2 Phosphoglucose isomerase FBPase PF00316.20 OEU16013.1 - 1.9e-34 118.8 0.1 2e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Fructose-1-6-bisphosphatase, N-terminal domain SIS PF01380.22 OEU16014.1 - 3.8e-33 114.1 0.5 1.5e-16 60.5 0.0 2.7 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OEU16014.1 - 7.4e-20 71.5 0.1 2e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OEU16014.1 - 4.5e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OEU16014.1 - 0.00018 20.5 0.1 0.00032 19.7 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 OEU16014.1 - 0.15 12.1 0.0 1.9 8.5 0.0 2.3 1 1 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain UAA PF08449.11 OEU16015.1 - 2.6e-54 184.5 14.0 2.8e-53 181.1 14.0 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU16015.1 - 2.4e-08 34.2 22.2 2.2e-06 27.9 8.6 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OEU16015.1 - 7.3e-07 28.6 3.9 0.00018 20.8 0.2 2.6 2 1 0 2 2 2 2 Nucleotide-sugar transporter UPF0220 PF05255.11 OEU16015.1 - 0.0013 18.3 2.7 0.13 11.8 0.0 2.6 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0220) NAD_binding_10 PF13460.6 OEU16016.1 - 2.2e-21 76.6 0.0 4e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OEU16016.1 - 9.7e-05 21.5 0.1 0.00015 20.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OEU16016.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OEU16016.1 - 0.15 12.5 0.1 1.2 9.6 0.1 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SET PF00856.28 OEU16017.1 - 4e-05 24.1 1.9 0.00023 21.6 0.9 2.4 2 1 0 2 2 2 1 SET domain 2OG-FeII_Oxy_3 PF13640.6 OEU16018.1 - 6e-05 23.9 0.2 0.00017 22.4 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 OEU16018.1 - 0.031 13.8 0.2 3.8 7.0 0.0 2.3 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA TF_Zn_Ribbon PF08271.12 OEU16019.1 - 3e-05 23.4 0.0 6.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Integrin_b_cyt PF08725.11 OEU16019.1 - 0.026 14.2 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain zf-CCHC PF00098.23 OEU16023.1 - 1e-08 34.8 2.0 2.1e-08 33.9 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 OEU16023.1 - 3.1e-08 33.8 0.4 3.1e-08 33.8 0.4 2.8 2 1 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC_5 PF14787.6 OEU16023.1 - 9.4e-05 22.0 0.5 0.0002 21.0 0.5 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OEU16023.1 - 0.00014 21.6 2.2 0.00029 20.6 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OEU16023.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Menin PF05053.13 OEU16023.1 - 0.41 8.9 3.8 0.63 8.3 3.8 1.3 1 0 0 1 1 1 0 Menin Melibiase PF02065.18 OEU16024.1 - 5e-13 48.7 0.0 6.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Melibiase GHL10 PF02638.15 OEU16024.1 - 6.3e-05 22.2 0.0 8.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 OEU16024.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Melibiase_2 PF16499.5 OEU16024.1 - 0.011 14.9 1.6 0.039 13.1 0.0 2.3 3 0 0 3 3 3 0 Alpha galactosidase A GHL15 PF14885.6 OEU16024.1 - 0.012 15.6 0.1 0.038 13.9 0.0 1.8 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Raffinose_syn PF05691.12 OEU16024.1 - 0.061 11.1 0.1 0.092 10.5 0.1 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Bud13 PF09736.9 OEU16025.1 - 1.7e-37 129.1 16.9 1.7e-37 129.1 16.9 1.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex HAD_SAK_2 PF18143.1 OEU16025.1 - 0.032 14.6 3.1 0.042 14.2 2.7 1.4 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Peptidase_S24 PF00717.23 OEU16026.1 - 3.4e-10 39.7 0.8 5.3e-10 39.1 0.8 1.3 1 0 0 1 1 1 1 Peptidase S24-like tRNA_U5-meth_tr PF05958.11 OEU16030.1 - 3.1e-20 72.5 0.0 5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OEU16030.1 - 3.6e-06 26.9 0.0 7.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16030.1 - 0.00017 22.2 0.0 0.00043 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU16030.1 - 0.0041 16.5 0.1 0.0077 15.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OEU16030.1 - 0.016 15.8 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 OEU16030.1 - 0.02 14.5 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Myc_N PF01056.18 OEU16030.1 - 0.033 14.1 0.3 0.066 13.1 0.3 1.5 1 0 0 1 1 1 0 Myc amino-terminal region N6_N4_Mtase PF01555.18 OEU16030.1 - 0.085 12.5 0.0 0.31 10.7 0.0 2.2 1 1 0 1 1 1 0 DNA methylase Cons_hypoth95 PF03602.15 OEU16030.1 - 0.12 12.1 0.1 0.28 10.8 0.1 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 OEU16030.1 - 0.33 10.4 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase EMP24_GP25L PF01105.24 OEU16031.1 - 1.3e-18 67.6 0.0 2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3923 PF13061.6 OEU16031.1 - 0.0079 16.3 0.5 0.015 15.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3923) GLTSCR1 PF15249.6 OEU16031.1 - 0.019 15.4 0.2 0.031 14.7 0.2 1.3 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein FAD_binding_7 PF03441.14 OEU16032.1 - 4e-26 91.8 0.0 5.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Pkinase PF00069.25 OEU16033.1 - 1.6e-19 70.3 0.0 2.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16033.1 - 0.0016 17.8 0.0 0.0044 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4233 PF14017.6 OEU16034.1 - 0.21 12.0 0.1 0.37 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Galactosyl_T PF01762.21 OEU16035.1 - 1.1e-24 87.3 0.5 3.2e-19 69.5 0.0 2.6 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 OEU16035.1 - 9.5e-10 38.3 0.0 9.5e-10 38.3 0.0 2.9 3 1 1 4 4 4 1 Fringe-like NTPase_I-T PF01931.18 OEU16036.1 - 7.7e-43 146.1 0.0 2.2e-41 141.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF84 Glyco_hydro_31 PF01055.26 OEU16037.1 - 1.1e-71 242.4 0.3 1.9e-71 241.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OEU16037.1 - 1.1e-10 41.6 0.9 8.2e-10 38.8 0.9 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5110) RelB_N PF18506.1 OEU16037.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain Amino_oxidase PF01593.24 OEU16040.1 - 1.3e-45 156.6 0.0 1.6e-45 156.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU16040.1 - 1.5e-08 34.8 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU16040.1 - 0.0014 18.3 0.0 0.0059 16.2 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OEU16040.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU16040.1 - 0.095 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU16040.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OEU16040.1 - 0.19 10.9 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 OEU16040.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Sec63 PF02889.16 OEU16041.1 - 0.053 12.7 0.0 0.79 8.8 0.0 2.3 2 1 0 2 2 2 0 Sec63 Brl domain DUF2188 PF09954.9 OEU16041.1 - 0.089 12.9 0.8 0.27 11.4 0.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) PVL_ORF50 PF07768.11 OEU16041.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.8 3 1 1 4 4 4 0 PVL ORF-50-like family RNA_pol_Rpc4 PF05132.14 OEU16041.1 - 0.3 11.5 1.9 1.9 8.9 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4366 PF14283.6 OEU16041.1 - 1.9 8.5 11.3 1.7 8.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Vfa1 PF08432.10 OEU16041.1 - 3.9 7.8 10.1 12 6.1 10.1 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-RING_2 PF13639.6 OEU16042.1 - 4e-07 30.3 11.7 4e-07 30.3 11.7 2.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OEU16042.1 - 1.7e-06 27.7 5.3 6.4e-06 25.8 5.3 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU16042.1 - 0.00018 21.7 10.5 0.00018 21.7 10.5 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU16042.1 - 0.0011 18.7 13.3 0.0039 17.0 13.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU16042.1 - 0.0017 18.4 8.6 0.0061 16.6 8.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OEU16042.1 - 0.0059 16.5 12.7 0.0059 16.5 12.7 2.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OEU16042.1 - 0.094 12.6 14.3 0.57 10.1 14.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU16042.1 - 0.34 10.8 16.5 0.9 9.4 16.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OEU16042.1 - 1.2 9.1 16.5 2.7 8.0 15.7 2.1 1 1 0 1 1 1 0 PHD-finger TB2_DP1_HVA22 PF03134.19 OEU16043.1 - 2.7e-16 59.3 2.0 3e-16 59.1 2.0 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GTP_EFTU PF00009.27 OEU16044.1 - 1.3e-51 175.0 0.0 2.2e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OEU16044.1 - 1.6e-19 69.7 0.0 3.9e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OEU16044.1 - 5.1e-08 33.2 1.4 1.5e-07 31.7 0.4 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU16044.1 - 2e-06 27.8 0.1 4.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OEU16044.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Septin EFG_II PF14492.6 OEU16044.1 - 0.0073 16.4 0.3 0.024 14.7 0.1 2.0 1 1 1 2 2 2 1 Elongation Factor G, domain II tRNA-synt_2b PF00587.25 OEU16045.1 - 7.2e-33 114.0 0.0 1.1e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OEU16045.1 - 2.1e-17 63.3 6.1 4.4e-17 62.3 6.1 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF2156 PF09924.9 OEU16045.1 - 0.093 11.7 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) zf-UBR PF02207.20 OEU16046.1 - 3.3e-18 65.6 14.4 5.6e-18 64.9 14.4 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) SRA PF18491.1 OEU16046.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 SET and RING associated domain TubC_N PF18563.1 OEU16046.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 TubC N-terminal docking domain Mucin PF01456.17 OEU16046.1 - 4.6 7.2 14.5 1.8 8.5 11.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Homeobox_KN PF05920.11 OEU16047.1 - 7.5e-12 45.0 1.0 1.5e-11 44.0 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OEU16047.1 - 0.095 12.6 0.4 0.44 10.4 0.0 2.2 1 1 1 2 2 2 0 Homeodomain FAD_binding_2 PF00890.24 OEU16048.1 - 2.5e-12 46.6 2.0 6.1e-07 28.9 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OEU16048.1 - 1.5e-10 41.1 0.0 3.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU16048.1 - 6.1e-09 35.7 0.1 0.002 17.5 0.2 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 OEU16048.1 - 6.4e-06 25.6 0.2 1.3e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OEU16048.1 - 7.5e-06 24.9 0.7 0.002 16.9 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 OEU16048.1 - 8.4e-06 25.2 0.1 5.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU16048.1 - 8.7e-06 25.5 3.8 0.00026 20.7 1.4 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU16048.1 - 7.1e-05 22.2 0.4 0.00012 21.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 OEU16048.1 - 0.00013 20.7 0.8 0.082 11.4 0.2 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 OEU16048.1 - 0.00072 18.9 0.4 0.0016 17.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU16048.1 - 0.0041 16.5 0.2 0.0041 16.5 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OEU16048.1 - 0.091 13.3 1.8 0.24 12.0 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU16048.1 - 0.2 10.7 3.0 0.25 10.4 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A PIG-P PF08510.12 OEU16049.1 - 0.051 13.5 0.1 0.48 10.4 0.1 2.7 1 0 0 1 1 1 0 PIG-P DA1-like PF12315.8 OEU16049.1 - 0.13 11.6 4.0 0.38 10.1 0.1 2.6 3 0 0 3 3 3 0 Protein DA1 Ni_hydr_CYTB PF01292.20 OEU16049.1 - 4.4 6.8 8.5 14 5.2 8.5 1.8 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 zf-RING_2 PF13639.6 OEU16050.1 - 7.8e-12 45.3 8.0 1.7e-11 44.2 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU16050.1 - 8.5e-10 38.8 6.8 1.2e-09 38.3 5.6 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU16050.1 - 5.2e-08 32.8 3.6 1.4e-07 31.4 3.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU16050.1 - 5.9e-07 29.2 6.9 1.7e-06 27.7 6.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU16050.1 - 2.1e-06 27.5 6.2 4.5e-06 26.4 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU16050.1 - 4.8e-06 26.2 2.9 4.8e-06 26.2 2.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 OEU16050.1 - 7.8e-06 25.8 4.7 2e-05 24.4 4.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU16050.1 - 4e-05 23.4 4.5 4e-05 23.4 4.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU16050.1 - 5.4e-05 23.0 4.6 9.5e-05 22.2 4.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU16050.1 - 9.6e-05 21.9 4.6 0.00023 20.7 4.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OEU16050.1 - 0.0026 17.9 3.2 0.0064 16.6 3.2 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain Rtf2 PF04641.12 OEU16050.1 - 0.0051 16.2 0.5 0.0069 15.8 0.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 OEU16050.1 - 0.0054 16.7 5.6 0.039 14.0 5.6 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 OEU16050.1 - 0.033 14.3 5.5 0.11 12.7 5.5 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_9 PF13901.6 OEU16050.1 - 0.09 12.7 3.3 0.18 11.7 3.3 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 OEU16050.1 - 0.31 11.4 5.9 0.75 10.2 5.9 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OEU16050.1 - 0.71 10.0 5.1 0.33 11.0 1.8 2.1 2 0 0 2 2 2 0 Zinc-finger Zf_RING PF16744.5 OEU16050.1 - 1.3 9.2 6.1 0.85 9.8 3.9 1.8 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_4 PF14570.6 OEU16050.1 - 1.4 8.7 4.7 6.2 6.7 4.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHC2_SAM_assoc PF16616.5 OEU16051.1 - 4.9 8.0 20.1 9.7 7.0 17.9 2.8 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 adh_short PF00106.25 OEU16052.1 - 8e-22 77.6 0.0 1.7e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU16052.1 - 1.7e-14 54.0 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU16052.1 - 3.1e-06 27.2 0.1 7.6e-06 26.0 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU16052.1 - 0.00041 19.9 0.0 0.00097 18.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OEU16052.1 - 0.017 15.0 0.1 0.033 14.1 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding CM2 PF03021.14 OEU16052.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein TPR_12 PF13424.6 OEU16053.1 - 2.4e-29 101.4 5.3 2.1e-13 50.3 0.1 3.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16053.1 - 3.4e-26 90.3 7.2 1.5e-06 27.9 0.1 5.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16053.1 - 7.4e-12 44.6 0.2 0.0023 17.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16053.1 - 1.3e-11 43.8 0.1 0.0011 19.0 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU16053.1 - 1.4e-11 43.5 2.2 0.0025 17.8 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU16053.1 - 4e-08 32.7 2.7 1 9.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU16053.1 - 2.7e-05 24.6 2.8 3.9 8.5 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU16053.1 - 3.1e-05 23.5 1.9 0.00014 21.4 1.3 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 OEU16053.1 - 0.00041 20.0 0.8 1.3 8.8 0.0 4.4 3 2 2 5 5 5 1 TPR repeat TPR_16 PF13432.6 OEU16053.1 - 0.00041 20.9 0.2 0.058 14.1 0.0 3.5 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU16053.1 - 0.0022 18.5 0.2 17 6.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU16053.1 - 0.016 15.7 1.0 0.41 11.2 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16053.1 - 0.027 14.8 0.2 0.14 12.6 0.0 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 OEU16053.1 - 0.029 14.5 0.9 0.56 10.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.9 OEU16053.1 - 0.062 12.3 0.0 0.52 9.3 0.0 2.1 1 1 1 2 2 2 0 RNA polymerase I-associated factor PAF67 ANAPC5 PF12862.7 OEU16053.1 - 0.065 13.3 1.2 9.9 6.3 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 OEU16053.1 - 0.12 12.5 0.5 11 6.1 0.0 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 OEU16053.1 - 0.22 11.9 2.8 0.33 11.4 0.8 2.3 1 1 0 2 2 2 0 Bacterial transcriptional activator domain zf-C3HC4_3 PF13920.6 OEU16054.1 - 5.2e-11 42.2 5.5 9.8e-11 41.4 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU16054.1 - 3.7e-10 39.5 5.6 7.4e-10 38.5 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU16054.1 - 2.6e-09 36.7 6.7 6.6e-09 35.5 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU16054.1 - 1.7e-08 34.6 6.7 3.4e-08 33.7 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OEU16054.1 - 3.3e-08 33.4 3.9 6.7e-08 32.4 3.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU16054.1 - 5e-08 33.0 7.6 1e-07 32.0 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OEU16054.1 - 3.4e-07 30.0 4.0 6.6e-07 29.1 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OEU16054.1 - 2.2e-05 24.3 6.0 4.6e-05 23.3 6.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Ank_4 PF13637.6 OEU16054.1 - 2.6e-05 24.7 0.1 0.00018 22.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-rbx1 PF12678.7 OEU16054.1 - 0.00037 20.7 3.4 0.00092 19.5 3.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Ank_2 PF12796.7 OEU16054.1 - 0.00053 20.5 0.1 0.011 16.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU16054.1 - 0.0016 18.8 2.6 1.8 9.4 0.1 4.1 5 0 0 5 5 4 1 Ankyrin repeat zf-RING_4 PF14570.6 OEU16054.1 - 0.13 12.1 7.8 0.3 10.9 7.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OEU16054.1 - 0.34 11.1 3.9 1.1 9.4 3.9 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 OEU16054.1 - 0.45 10.3 4.7 1.2 9.0 4.7 1.8 1 1 0 1 1 1 0 RING-like zinc finger zinc_ribbon_9 PF14369.6 OEU16054.1 - 1.8 8.9 9.7 0.051 13.9 2.8 2.1 3 0 0 3 3 1 0 zinc-ribbon PPR_3 PF13812.6 OEU16055.1 - 3.3e-35 120.0 1.7 4.8e-08 33.0 0.0 5.7 3 1 3 6 6 6 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 OEU16055.1 - 1.6e-34 117.8 12.4 3.5e-08 33.5 0.0 6.7 3 3 4 7 7 7 7 PPR repeat family PPR PF01535.20 OEU16055.1 - 9.8e-24 81.9 13.7 7.3e-05 22.7 0.1 7.6 8 1 0 8 8 8 5 PPR repeat PPR_1 PF12854.7 OEU16055.1 - 1.1e-19 69.7 3.0 1.2e-05 24.9 0.0 8.3 8 1 0 8 8 8 2 PPR repeat PPR_long PF17177.4 OEU16055.1 - 1.2e-18 67.2 4.4 2.3e-10 40.2 0.8 3.1 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OEU16055.1 - 0.012 16.4 0.4 34 5.6 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 OEU16055.1 - 0.087 13.0 0.1 6.6 6.9 0.0 2.3 1 1 1 2 2 2 0 Putative Mad3/BUB1 like region 1 protein FKBP_C PF00254.28 OEU16056.1 - 1.3e-06 28.6 0.0 2.1e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dexa_ind PF15198.6 OEU16057.1 - 0.031 14.4 0.7 0.068 13.3 0.7 1.6 1 0 0 1 1 1 0 Dexamethasone-induced Myc_target_1 PF15179.6 OEU16057.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.1 3 0 0 3 3 3 0 Myc target protein 1 TMEMspv1-c74-12 PF11044.8 OEU16057.1 - 0.82 9.7 3.5 1.8 8.6 3.5 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MS_channel PF00924.18 OEU16058.1 - 4.3e-27 95.0 0.1 5e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Methyltransf_25 PF13649.6 OEU16059.1 - 4.4e-12 46.6 0.0 8.6e-10 39.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU16059.1 - 4.9e-11 42.4 0.3 3.2e-06 26.7 0.2 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OEU16059.1 - 1.5e-10 41.6 0.0 1.8e-09 38.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU16059.1 - 1.1e-09 38.2 0.0 9.5e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16059.1 - 6.6e-09 35.8 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16059.1 - 8.8e-09 36.0 0.1 2.4e-08 34.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain NodS PF05401.11 OEU16059.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 OEU16059.1 - 0.0022 17.5 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OEU16059.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OEU16059.1 - 0.0074 16.3 0.1 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OEU16059.1 - 0.019 14.5 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 OEU16059.1 - 0.027 14.0 0.2 0.076 12.5 0.2 1.8 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Cons_hypoth95 PF03602.15 OEU16059.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 OEU16059.1 - 0.046 12.8 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 OEU16059.1 - 0.055 12.6 0.2 0.085 11.9 0.2 1.2 1 0 0 1 1 1 0 DREV methyltransferase His_Phos_1 PF00300.22 OEU16060.1 - 4.7e-11 42.7 0.0 3.2e-06 27.0 0.0 2.4 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 OEU16061.1 - 0.018 14.9 0.0 0.087 12.7 0.0 2.2 2 0 0 2 2 2 0 F-box-like L_protein_N PF15518.6 OEU16061.1 - 0.076 12.9 0.6 0.16 11.8 0.2 1.7 2 0 0 2 2 2 0 L protein N-terminus Y_phosphatase3 PF13350.6 OEU16063.1 - 2.2e-25 90.0 0.0 5.8e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 OEU16063.1 - 0.0038 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 OEU16063.1 - 0.0061 16.8 0.7 0.058 13.7 0.0 2.7 3 0 0 3 3 3 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 OEU16063.1 - 0.0065 16.6 0.2 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Myotub-related PF06602.14 OEU16063.1 - 0.012 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.13 OEU16063.1 - 0.078 12.6 0.2 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Transposase_21 PF02992.14 OEU16063.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 FAM104 PF15434.6 OEU16064.1 - 0.034 14.7 8.4 0.039 14.5 8.4 1.1 1 0 0 1 1 1 0 Family 104 RRXRR PF14239.6 OEU16064.1 - 0.037 13.9 2.0 0.037 13.9 2.0 1.0 1 0 0 1 1 1 0 RRXRR protein SR-25 PF10500.9 OEU16064.1 - 0.21 11.2 15.0 0.22 11.1 15.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 OEU16064.1 - 0.34 11.8 11.6 0.43 11.5 11.6 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 OEU16064.1 - 4.3 8.4 8.8 4.3 8.4 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 OEU16064.1 - 7.8 5.1 8.3 8.1 5.1 8.3 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OEU16064.1 - 8.5 5.0 10.3 8.8 5.0 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asp PF00026.23 OEU16065.1 - 1.2e-97 327.1 0.4 1.4e-97 326.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OEU16065.1 - 8.1e-14 52.2 2.0 6.9e-11 42.7 2.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OEU16065.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3006 PF11213.8 OEU16067.1 - 8.6e-06 25.9 14.1 39 4.6 0.2 7.8 7 1 0 7 7 7 6 Protein of unknown function (DUF3006) AOC_like PF18678.1 OEU16067.1 - 0.0047 16.5 3.0 0.78 9.3 0.1 3.8 2 1 1 4 4 4 2 Allene oxide cyclase barrel like domain DnaJ PF00226.31 OEU16068.1 - 1.3e-23 82.8 0.8 1.6e-23 82.6 0.8 1.1 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 OEU16070.1 - 8.3e-28 97.5 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16070.1 - 6.7e-17 61.6 0.0 8.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU16070.1 - 2.8e-09 36.3 0.1 4.5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU16070.1 - 0.001 19.0 0.0 0.006 16.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OEU16070.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cgr1 PF03879.14 OEU16071.1 - 6.4e-06 26.5 25.8 5.3e-05 23.6 25.8 1.9 1 1 0 1 1 1 1 Cgr1 family zf-RING_2 PF13639.6 OEU16072.1 - 1.1e-10 41.7 8.7 2.2e-10 40.7 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU16072.1 - 4.2e-07 29.6 7.1 7e-07 28.9 6.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU16072.1 - 2.5e-06 27.2 10.3 6.1e-06 26.0 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU16072.1 - 1e-05 25.7 11.5 3.5e-05 24.0 11.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU16072.1 - 1.3e-05 24.9 8.0 3.8e-05 23.4 8.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU16072.1 - 1.4e-05 25.1 6.5 2.6e-05 24.1 5.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU16072.1 - 7e-05 22.7 8.6 0.00013 21.8 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OEU16072.1 - 0.0021 18.1 6.1 0.0066 16.5 6.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OEU16072.1 - 0.0032 17.0 8.1 0.0062 16.1 8.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU16072.1 - 0.0035 17.2 7.9 0.0063 16.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OEU16072.1 - 0.03 14.1 3.1 0.073 12.9 3.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 OEU16072.1 - 0.058 13.5 4.4 0.11 12.6 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zf_RING PF16744.5 OEU16072.1 - 0.18 12.0 5.9 0.39 10.9 6.0 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 OEU16072.1 - 0.23 11.4 6.8 0.52 10.3 6.8 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OEU16072.1 - 0.3 11.3 8.0 2.5 8.3 8.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OEU16072.1 - 0.36 10.8 6.8 0.3 11.0 2.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 OEU16072.1 - 0.43 10.7 9.0 1 9.6 9.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 OEU16072.1 - 0.46 10.6 5.9 1.6 8.9 5.9 1.9 1 1 0 1 1 1 0 Zinc-finger Zn-ribbon_8 PF09723.10 OEU16072.1 - 3.6 7.8 6.0 2.2e+02 2.1 6.0 2.4 1 1 0 1 1 1 0 Zinc ribbon domain zf-P11 PF03854.14 OEU16072.1 - 4.6 7.0 9.9 8.8 6.1 8.7 2.0 1 1 1 2 2 2 0 P-11 zinc finger Dioxygenase_C PF00775.21 OEU16075.1 - 7.9e-14 51.5 0.4 3.4e-12 46.2 0.4 2.3 1 1 0 1 1 1 1 Dioxygenase PT PF04886.12 OEU16075.1 - 1.3 8.6 21.6 0.03 13.9 3.2 3.7 3 0 0 3 3 3 0 PT repeat Abhydrolase_1 PF00561.20 OEU16076.1 - 5.6e-10 39.3 0.0 5.6e-10 39.3 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU16076.1 - 1.9e-06 28.7 0.0 2.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU16076.1 - 0.00068 19.0 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OEU16076.1 - 0.0093 16.1 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Nop14 PF04147.12 OEU16076.1 - 0.055 11.7 15.7 0.088 11.0 15.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OEU16076.1 - 0.66 9.3 15.5 1.2 8.4 15.5 1.3 1 0 0 1 1 1 0 BUD22 NESP55 PF06390.12 OEU16076.1 - 0.82 9.2 7.0 1.9 8.1 7.0 1.6 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) SID-1_RNA_chan PF13965.6 OEU16076.1 - 1.9 6.8 7.2 2.8 6.2 7.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 OEU16076.1 - 6.9 5.5 7.6 13 4.6 7.6 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Glycos_transf_1 PF00534.20 OEU16077.1 - 1.9e-29 102.4 0.0 3.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU16077.1 - 4.2e-25 88.7 0.0 7.7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OEU16077.1 - 3e-21 76.2 0.0 9.4e-21 74.5 0.0 1.9 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OEU16077.1 - 1.3e-12 48.5 0.0 1.2e-11 45.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OEU16077.1 - 6.8e-09 36.0 0.0 4e-08 33.5 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OEU16077.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferase 4-like HSF_DNA-bind PF00447.17 OEU16078.1 - 4.5e-16 59.2 0.1 5.3e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1430 PF07242.11 OEU16078.1 - 0.15 12.4 0.5 0.2 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Flavodoxin_1 PF00258.25 OEU16079.1 - 1.3e-18 67.6 0.1 3e-17 63.1 0.1 2.0 1 1 0 1 1 1 1 Flavodoxin PUB PF09409.10 OEU16080.1 - 6.5e-06 26.0 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 PUB domain AJAP1_PANP_C PF15298.6 OEU16080.1 - 3.7 7.7 10.2 0.75 10.0 6.1 1.8 1 1 0 2 2 2 0 AJAP1/PANP C-terminus TIP41 PF04176.13 OEU16081.1 - 3.3e-12 46.2 2.8 5.6e-05 22.7 0.3 3.6 2 2 0 2 2 2 2 TIP41-like family SET PF00856.28 OEU16082.1 - 0.00061 20.2 0.0 0.0027 18.1 0.0 2.2 2 1 0 2 2 2 1 SET domain Zwilch PF09817.9 OEU16082.1 - 0.097 11.1 0.1 0.84 8.0 0.0 2.1 2 0 0 2 2 2 0 RZZ complex, subunit zwilch ABC2_membrane_3 PF12698.7 OEU16083.1 - 2.6e-42 145.2 14.6 4.6e-42 144.4 14.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OEU16083.1 - 8.1e-25 87.9 0.0 1e-21 77.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU16083.1 - 1.1e-11 45.1 0.0 0.00015 21.7 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system HEAT PF02985.22 OEU16084.1 - 5.7e-42 138.1 22.0 0.00076 19.5 0.0 19.2 20 1 0 21 21 20 9 HEAT repeat HEAT_2 PF13646.6 OEU16084.1 - 2e-34 117.8 32.5 4e-05 23.9 0.0 13.6 7 4 8 15 15 15 12 HEAT repeats HEAT_EZ PF13513.6 OEU16084.1 - 2.6e-30 104.4 29.9 0.0006 20.3 0.0 17.7 15 4 6 21 21 20 6 HEAT-like repeat Cnd1 PF12717.7 OEU16084.1 - 2.5e-21 76.4 7.4 0.0026 17.8 0.0 9.1 7 3 2 9 9 9 6 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OEU16084.1 - 1.8e-18 66.9 0.0 0.045 14.4 0.0 9.6 8 3 2 10 10 10 5 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OEU16084.1 - 1.9e-14 53.8 0.0 3.1e-05 23.6 0.0 6.4 5 2 1 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 OEU16084.1 - 2.6e-12 46.1 5.5 0.002 16.8 0.8 6.8 5 1 0 6 6 6 3 Adaptin N terminal region IFRD PF05004.13 OEU16084.1 - 1.2e-08 34.4 3.6 0.27 10.3 0.0 7.7 4 4 3 8 8 8 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 OEU16084.1 - 1.8e-06 27.8 0.1 3 7.8 0.0 5.5 4 1 0 4 4 4 2 UME (NUC010) domain ParcG PF10274.9 OEU16084.1 - 1.8e-05 24.9 2.7 5.7 7.0 0.0 6.4 7 2 1 8 8 7 1 Parkin co-regulated protein Arm PF00514.23 OEU16084.1 - 2.6e-05 24.1 7.0 10 6.3 0.0 9.8 12 0 0 12 12 11 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 OEU16084.1 - 0.00047 20.0 3.4 0.13 12.0 0.0 4.4 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) Ipi1_N PF12333.8 OEU16084.1 - 0.045 14.3 0.6 9.8 6.8 0.0 4.6 5 1 0 5 5 3 0 Rix1 complex component involved in 60S ribosome maturation Ecm29 PF13001.7 OEU16084.1 - 0.086 11.5 0.1 3.3 6.3 0.0 3.3 2 1 0 3 3 3 0 Proteasome stabiliser PfUIS3 PF11567.8 OEU16084.1 - 0.16 12.4 0.2 0.39 11.1 0.2 1.6 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein MMS19_C PF12460.8 OEU16084.1 - 0.18 10.9 16.9 5.8 5.9 4.4 6.3 4 2 1 5 5 5 0 RNAPII transcription regulator C-terminal RRM_1 PF00076.22 OEU16087.1 - 1.7e-21 75.8 0.1 2e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OEU16087.1 - 6.1e-06 26.0 0.0 9.7e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 OEU16087.1 - 0.014 15.6 0.6 1.4 9.1 0.1 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RNA_bind PF08675.11 OEU16087.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 OEU16087.1 - 0.032 14.2 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OEU16087.1 - 0.042 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif DUF1492 PF07374.11 OEU16089.1 - 0.01 16.0 1.9 0.01 16.0 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) AXH PF08517.12 OEU16089.1 - 3 8.4 6.8 5.8 7.5 0.2 3.1 2 0 0 2 2 2 0 Ataxin-1 and HBP1 module (AXH) adh_short PF00106.25 OEU16090.1 - 1.5e-28 99.6 0.0 3.2e-27 95.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU16090.1 - 4.8e-12 45.9 0.0 2.7e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU16090.1 - 6e-07 29.5 0.0 8.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU16090.1 - 0.026 14.0 0.0 0.048 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OEU16090.1 - 0.13 12.0 0.4 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thymidylat_synt PF00303.19 OEU16090.1 - 0.19 10.9 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Thymidylate synthase E1-E2_ATPase PF00122.20 OEU16091.1 - 7.4e-34 116.8 1.4 7.4e-34 116.8 1.4 3.8 5 1 1 6 6 6 1 E1-E2 ATPase Hydrolase PF00702.26 OEU16091.1 - 6e-12 46.3 0.1 1e-11 45.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OEU16091.1 - 1.7e-11 43.6 1.4 2.5e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OEU16091.1 - 0.0029 17.4 0.8 0.0054 16.5 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2407 PF10302.9 OEU16092.1 - 0.00022 21.7 0.0 0.0012 19.3 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OEU16092.1 - 0.00088 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family SDA1 PF05285.12 OEU16092.1 - 0.19 11.1 17.6 0.63 9.4 1.2 2.4 2 0 0 2 2 2 0 SDA1 DNA_pol_phi PF04931.13 OEU16092.1 - 0.82 7.7 21.7 0.2 9.7 7.4 2.1 2 0 0 2 2 2 0 DNA polymerase phi zf-HIT PF04438.16 OEU16094.1 - 1.9e-05 24.4 12.3 3.4e-05 23.6 12.3 1.4 1 0 0 1 1 1 1 HIT zinc finger Sulfotransfer_1 PF00685.27 OEU16095.1 - 2.8e-10 40.1 0.3 4.8e-10 39.4 0.3 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU16095.1 - 2.1e-07 31.5 0.5 0.00017 22.1 0.2 3.1 2 1 0 2 2 2 1 Sulfotransferase family LRR_6 PF13516.6 OEU16096.1 - 3.2e-05 23.6 10.4 0.0091 16.0 0.3 4.9 4 0 0 4 4 4 3 Leucine Rich repeat Stk19 PF10494.9 OEU16097.1 - 3.1e-09 36.9 1.4 3.1e-09 36.9 1.4 3.0 2 1 0 2 2 2 1 Serine-threonine protein kinase 19 DapB_C PF05173.14 OEU16097.1 - 0.059 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus PGAP1 PF07819.13 OEU16098.1 - 2.1e-21 76.7 1.2 1.8e-13 50.8 0.2 2.5 2 0 0 2 2 2 2 PGAP1-like protein TctB PF07331.11 OEU16098.1 - 0.49 10.7 10.1 4.2 7.7 0.1 3.7 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family V-SNARE PF05008.15 OEU16099.1 - 5.1e-10 39.6 2.0 5.1e-10 39.6 2.0 2.8 2 2 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OEU16099.1 - 5.2e-10 39.5 4.6 5.2e-10 39.5 4.6 2.1 1 1 1 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OEU16099.1 - 0.00036 20.4 1.7 0.00036 20.4 1.7 2.2 2 1 0 2 2 2 1 Sec20 DUF2353 PF09789.9 OEU16099.1 - 0.0089 15.4 12.1 0.012 15.0 12.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ThiD2 PF17792.1 OEU16099.1 - 0.68 10.4 6.9 0.3 11.6 2.5 2.4 1 1 1 2 2 2 0 ThiD2 family DUF745 PF05335.13 OEU16099.1 - 4.6 6.9 12.9 2 8.1 8.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CCDC-167 PF15188.6 OEU16099.1 - 6.5 7.2 10.1 0.24 11.8 1.6 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4149 PF13664.6 OEU16101.1 - 2e-27 95.5 3.9 2e-27 95.5 3.9 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 OEU16101.1 - 1.1e-05 25.7 0.6 4e-05 23.9 0.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5527 PF17665.1 OEU16101.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5527) DUF4013 PF13197.6 OEU16101.1 - 0.96 9.3 8.8 0.06 13.2 3.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) SET PF00856.28 OEU16102.1 - 8.2e-08 32.8 0.0 3.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 SET domain Av_adeno_fibre PF06536.11 OEU16102.1 - 0.019 14.8 0.6 0.19 11.6 0.0 2.5 3 0 0 3 3 3 0 Avian adenovirus fibre, N-terminal Helicase_C PF00271.31 OEU16103.1 - 2.3e-20 73.0 0.2 1.5e-17 64.0 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 OEU16103.1 - 1.8e-17 63.7 0.0 4.6e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase CarD_CdnL_TRCF PF02559.16 OEU16103.1 - 6.1e-07 30.1 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 OEU16103.1 - 0.00014 22.2 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 TRCF domain ResIII PF04851.15 OEU16103.1 - 0.006 16.6 0.0 0.044 13.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU16103.1 - 0.12 12.7 0.2 1.1 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain Helicase_C PF00271.31 OEU16104.1 - 1.5e-26 92.9 0.2 2e-26 92.5 0.2 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OEU16104.1 - 0.022 13.5 0.0 0.027 13.3 0.0 1.0 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HWE_HK PF07536.14 OEU16104.1 - 0.064 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 HWE histidine kinase SIR2 PF02146.17 OEU16105.1 - 1.1e-26 93.9 0.1 9.3e-24 84.3 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Prok-RING_1 PF14446.6 OEU16105.1 - 0.18 11.7 2.6 5.7 6.9 0.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 NeA_P2 PF12312.8 OEU16106.1 - 0.09 12.2 1.3 0.2 11.1 1.3 1.5 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DUF3439 PF11921.8 OEU16107.1 - 8.6 6.4 27.7 5.5 7.0 11.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Fasciclin PF02469.22 OEU16108.1 - 3.2e-07 30.6 0.0 4.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain CD24 PF14984.6 OEU16108.1 - 0.21 11.8 2.1 0.73 10.1 2.1 1.9 1 0 0 1 1 1 0 CD24 protein PMSR PF01625.21 OEU16109.1 - 3.3e-48 163.7 0.3 3.9e-48 163.5 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SpoU_methylase PF00588.19 OEU16110.1 - 8.7e-27 94.0 0.0 1.5e-25 90.0 0.0 2.4 2 1 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OEU16110.1 - 7.7e-05 22.9 0.1 0.0012 19.1 0.0 2.5 2 1 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding LRR_8 PF13855.6 OEU16111.1 - 1.9e-06 27.5 10.5 0.0019 17.9 1.2 3.7 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OEU16111.1 - 2.8e-06 27.6 12.8 0.00074 19.9 1.9 4.8 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU16111.1 - 0.0018 18.5 10.5 4 8.4 1.3 5.8 7 0 0 7 7 7 2 Leucine Rich Repeat CxC6 PF18721.1 OEU16112.1 - 0.55 10.5 18.7 3.3 8.0 5.9 3.7 1 1 2 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases RCSD PF05177.12 OEU16112.1 - 6.3 7.8 9.0 0.39 11.7 1.7 3.0 3 0 0 3 3 3 0 RCSD region Phostensin_N PF13916.6 OEU16113.1 - 0.01 16.2 11.6 0.26 11.6 0.6 4.0 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal DUF525 PF04379.14 OEU16115.1 - 2.7e-23 82.0 0.0 3e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 ApaG domain DUF4354 PF14263.6 OEU16115.1 - 0.08 12.8 0.0 0.09 12.6 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4354) DUF525 PF04379.14 OEU16116.1 - 6e-22 77.7 0.0 6.5e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 ApaG domain Methyltransf_16 PF10294.9 OEU16117.1 - 1.2e-14 54.4 0.0 2.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase DUF1929 PF09118.11 OEU16117.1 - 0.13 12.6 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) CENP-B_dimeris PF09026.10 OEU16117.1 - 1.1 9.7 9.8 2.2 8.7 9.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fasciclin PF02469.22 OEU16119.1 - 1.9e-19 70.1 0.0 2.2e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain DUF4993 PF16384.5 OEU16119.1 - 0.15 11.0 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Fasciclin PF02469.22 OEU16120.1 - 3.5e-19 69.3 0.0 4.2e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain UPF0515 PF15135.6 OEU16121.1 - 3.9e-11 42.8 5.2 3.9e-11 42.8 5.2 1.8 2 0 0 2 2 2 1 Uncharacterised protein UPF0515 zf-3CxxC_2 PF17180.4 OEU16121.1 - 8.2e-08 32.9 1.6 8.2e-08 32.9 1.6 3.7 6 0 0 6 6 6 1 Zinc-binding domain Stc1 PF12898.7 OEU16121.1 - 0.0049 17.4 0.1 0.0049 17.4 0.1 3.8 3 1 1 4 4 4 2 Stc1 domain Ribosomal_L5_C PF00673.21 OEU16121.1 - 0.11 12.7 0.1 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 ribosomal L5P family C-terminus Cytomega_UL20A PF05984.12 OEU16121.1 - 6.9 7.0 9.0 0.27 11.5 0.9 2.3 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein SMC_N PF02463.19 OEU16122.1 - 3.6e-56 190.0 22.6 1.1e-55 188.5 22.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OEU16122.1 - 2.1e-21 76.4 0.0 6e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OEU16122.1 - 4.2e-12 46.5 6.4 3.1e-06 27.2 0.0 3.7 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OEU16122.1 - 3.7e-07 29.8 0.0 8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU16122.1 - 7.7e-05 23.3 48.3 7.7e-05 23.3 48.3 7.0 3 2 0 4 4 4 1 AAA domain AAA_15 PF13175.6 OEU16122.1 - 0.00018 21.4 26.5 0.00018 21.4 26.5 6.0 2 2 2 4 4 4 1 AAA ATPase domain DUF4407 PF14362.6 OEU16122.1 - 0.0018 17.7 19.9 0.0018 17.7 19.9 6.4 3 2 3 6 6 6 1 Domain of unknown function (DUF4407) sCache_2 PF17200.4 OEU16122.1 - 0.083 12.7 3.7 0.18 11.7 0.5 3.3 3 0 0 3 3 3 0 Single Cache domain 2 Surfac_D-trimer PF09006.11 OEU16122.1 - 0.46 10.4 2.3 1.2 9.1 0.6 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Prp19 PF08606.11 OEU16123.1 - 1.5e-27 95.3 2.4 3.1e-27 94.3 2.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 OEU16123.1 - 8.3e-10 39.1 0.9 0.0031 18.3 0.0 5.3 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU16123.1 - 1.8e-06 28.2 2.3 0.0012 19.1 0.1 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU16123.1 - 0.00054 19.9 1.6 0.005 16.7 0.2 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 OEU16123.1 - 0.014 15.9 0.0 9.2 6.9 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain ATP-synt_D PF01813.17 OEU16123.1 - 0.054 13.3 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 ATP synthase subunit D SRP54_N PF02881.19 OEU16123.1 - 0.06 13.6 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain BBS2_Mid PF14783.6 OEU16123.1 - 0.07 13.2 1.3 0.78 9.8 0.3 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SUKH_6 PF14568.6 OEU16123.1 - 0.15 12.5 0.1 2.8 8.4 0.0 2.9 1 1 2 3 3 3 0 SMI1-KNR4 cell-wall CortBP2 PF09727.9 OEU16123.1 - 0.18 11.7 2.0 1.8 8.5 0.5 2.4 2 0 0 2 2 2 0 Cortactin-binding protein-2 Afi1 PF07792.12 OEU16124.1 - 5 7.6 11.1 10 6.6 1.4 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Anoctamin PF04547.12 OEU16126.1 - 4.7e-07 29.0 1.4 5.7e-07 28.7 1.4 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 OEU16126.1 - 5.7e-06 25.8 3.6 7.6e-06 25.4 3.6 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate EcKinase PF02958.20 OEU16127.1 - 8.6e-14 51.5 0.0 3e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OEU16127.1 - 6.7e-07 29.5 0.1 1.3e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU16127.1 - 0.011 15.1 0.2 0.022 14.1 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM100 PF16311.5 OEU16127.1 - 0.059 13.0 0.3 0.16 11.5 0.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 zf-MYND PF01753.18 OEU16129.1 - 5.3e-07 29.6 14.0 1.1e-06 28.6 14.0 1.5 1 0 0 1 1 1 1 MYND finger DUF3449 PF11931.8 OEU16129.1 - 0.014 15.2 1.1 0.021 14.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) PALP PF00291.25 OEU16130.1 - 9e-67 225.5 0.2 1e-66 225.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SRA PF18491.1 OEU16131.1 - 0.046 13.8 3.8 0.073 13.2 3.8 1.4 1 0 0 1 1 1 0 SET and RING associated domain Methyltransf_2 PF00891.18 OEU16132.1 - 9.1e-32 110.1 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OEU16132.1 - 4.6e-06 26.5 0.0 8.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 OEU16132.1 - 0.0078 16.9 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16132.1 - 0.029 15.1 0.0 0.068 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_15 PF01793.16 OEU16135.1 - 0.00087 18.6 7.5 0.0077 15.5 7.5 2.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIR2 PF02146.17 OEU16136.1 - 1e-54 185.1 0.0 1.4e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family RXT2_N PF08595.11 OEU16136.1 - 1.3 9.0 9.1 2.3 8.3 9.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 OEU16136.1 - 8.6 5.6 27.9 45 3.2 27.9 1.8 1 1 0 1 1 1 0 NOA36 protein Cpn60_TCP1 PF00118.24 OEU16137.1 - 4.1e-141 471.0 9.9 4.6e-141 470.8 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltransf_28 PF02636.17 OEU16138.1 - 1e-58 199.0 0.1 1.6e-58 198.4 0.1 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1295 PF06966.12 OEU16139.1 - 1.8e-14 53.9 1.4 3.7e-14 52.8 1.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OEU16139.1 - 8.8e-06 26.1 0.4 0.00031 21.1 0.0 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 OEU16139.1 - 6.1e-05 23.0 2.4 0.0018 18.2 0.1 2.6 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OEU16139.1 - 0.00031 21.1 2.3 0.0026 18.1 0.1 2.7 2 2 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 OEU16139.1 - 0.0059 15.4 0.7 0.0097 14.7 0.2 1.6 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4233 PF14017.6 OEU16139.1 - 0.07 13.5 0.3 0.07 13.5 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) DUF4395 PF14340.6 OEU16139.1 - 0.076 13.3 0.2 0.076 13.3 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) DUF1013 PF06242.11 OEU16140.1 - 0.03 14.4 3.8 1.1 9.3 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1013) TRAP_alpha PF03896.16 OEU16140.1 - 1.6 7.8 23.4 1.4 8.1 3.4 3.7 1 1 5 6 6 6 0 Translocon-associated protein (TRAP), alpha subunit Mog1 PF04603.12 OEU16140.1 - 9.5 6.6 11.2 6.5e+03 -2.6 11.2 3.5 1 1 0 1 1 1 0 Ran-interacting Mog1 protein Nrap_D4 PF17405.2 OEU16141.1 - 3.7e-28 98.4 0.0 1.7e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 OEU16141.1 - 4.6e-28 98.0 0.2 1.7e-26 92.9 0.0 3.0 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 OEU16141.1 - 1.4e-25 90.3 0.1 6e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 OEU16141.1 - 1.7e-19 70.3 0.1 4.3e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 OEU16141.1 - 1.1e-13 51.6 0.0 3.1e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 OEU16141.1 - 1.4e-12 47.7 0.4 4.4e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Tim17 PF02466.19 OEU16142.1 - 6.1e-27 94.2 7.4 9.4e-27 93.6 7.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tmemb_14 PF03647.13 OEU16143.1 - 7.4e-22 77.9 11.2 8e-22 77.8 11.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Glug PF07581.12 OEU16143.1 - 4.5 7.9 6.1 58 4.4 0.1 3.5 3 1 0 3 3 3 0 The GLUG motif RRM_1 PF00076.22 OEU16144.1 - 2.7e-16 59.1 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU16144.1 - 6.9e-06 25.7 0.0 8.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OEU16144.1 - 0.0005 20.1 0.1 0.0007 19.6 0.1 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 OEU16144.1 - 0.0055 16.5 0.1 0.0096 15.8 0.1 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif DUF4904 PF16247.5 OEU16144.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) Rhamno_transf PF11316.8 OEU16146.1 - 1.5e-08 34.4 0.1 0.00014 21.3 0.1 2.4 2 0 0 2 2 2 2 Putative rhamnosyl transferase NMT PF01233.19 OEU16147.1 - 4.5e-75 250.9 0.4 1.4e-72 242.8 0.0 2.1 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 OEU16147.1 - 2.7e-65 219.8 3.1 1.8e-64 217.1 2.7 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 OEU16147.1 - 3.1e-05 24.2 0.0 7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OEU16147.1 - 0.051 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Cupin_2 PF07883.11 OEU16149.1 - 2.6e-07 30.3 0.1 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OEU16149.1 - 3.7e-06 26.5 1.3 0.065 12.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding_2 PF14525.6 OEU16149.1 - 0.00017 21.3 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 2 AraC-binding-like domain EutQ PF06249.12 OEU16149.1 - 0.00082 19.2 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 OEU16149.1 - 0.012 15.6 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain BspA_v PF18220.1 OEU16149.1 - 0.18 11.9 0.0 3.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Adhesin BspA variable domain DUF1884 PF08967.10 OEU16150.1 - 0.16 12.3 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) Phage_Coat_B PF05356.11 OEU16151.1 - 0.045 13.6 0.2 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 Phage Coat protein B ArsA_ATPase PF02374.15 OEU16153.1 - 1.4e-104 349.6 0.1 6.1e-102 340.9 0.1 2.0 1 1 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OEU16153.1 - 9.6e-14 51.7 0.1 2.4e-13 50.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 OEU16153.1 - 9.2e-13 48.4 0.0 3.5e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 OEU16153.1 - 7.5e-07 28.9 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 OEU16153.1 - 2.2e-06 27.3 0.3 0.00048 19.6 0.1 2.9 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 OEU16153.1 - 6.8e-05 22.6 0.3 0.0035 17.0 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 OEU16153.1 - 0.00074 19.1 0.0 0.0019 17.8 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 OEU16153.1 - 0.0021 17.7 0.1 0.028 14.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OEU16153.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MeaB PF03308.16 OEU16153.1 - 0.033 13.2 0.1 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OEU16153.1 - 0.12 11.5 0.1 0.27 10.4 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.11 OEU16153.1 - 0.49 9.6 1.5 3.5 6.9 0.2 2.2 1 1 0 2 2 2 0 ATPase MipZ DUF308 PF03729.13 OEU16154.1 - 0.0064 16.8 3.8 0.015 15.6 3.8 1.6 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) PASTA PF03793.19 OEU16154.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 PASTA domain Octopine_DH PF02317.17 OEU16155.1 - 6.6e-33 113.9 0.0 9.9e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 OEU16155.1 - 0.00015 22.3 0.9 0.0016 19.0 0.9 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Staph_opine_DH PF10100.9 OEU16155.1 - 0.0032 16.2 0.1 0.0045 15.7 0.1 1.1 1 0 0 1 1 1 1 Staphylopine dehydrogenase NAD_Gly3P_dh_N PF01210.23 OEU16155.1 - 0.0084 16.1 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OEU16155.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF563 PF04577.14 OEU16155.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF563) 2-Hacid_dh_C PF02826.19 OEU16155.1 - 0.15 11.4 0.0 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Presenilin PF01080.17 OEU16157.1 - 6.6 5.4 9.9 8.3 5.0 9.9 1.1 1 0 0 1 1 1 0 Presenilin FUSC PF04632.12 OEU16158.1 - 1.2 7.5 3.3 2.5 6.6 3.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 OEU16158.1 - 1.5 7.9 17.8 0.84 8.7 15.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 OEU16158.1 - 5.7 7.7 15.8 1.2 9.9 9.3 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Utp14 PF04615.13 OEU16158.1 - 8.3 4.8 43.9 5.8 5.4 30.7 2.3 2 0 0 2 2 2 0 Utp14 protein DUF1664 PF07889.12 OEU16158.1 - 9.6 6.3 10.8 2.9 7.9 5.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GCD14 PF08704.10 OEU16159.1 - 1.7e-65 221.2 0.0 1.9e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 OEU16159.1 - 0.00083 19.1 0.5 0.0043 16.9 0.0 2.1 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 OEU16159.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OEU16159.1 - 0.0059 16.4 0.0 0.01 15.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain LRR_8 PF13855.6 OEU16160.1 - 8.3e-11 41.5 0.6 0.00076 19.2 0.1 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU16160.1 - 2.4e-08 34.1 0.6 0.00022 21.6 0.0 3.2 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU16160.1 - 0.00023 21.3 0.0 2.8 8.9 0.0 4.1 5 0 0 5 5 5 1 Leucine Rich Repeat MukB PF04310.12 OEU16160.1 - 0.1 12.4 0.0 0.43 10.4 0.0 1.9 1 1 1 2 2 2 0 MukB N-terminal Guanylate_cyc PF00211.20 OEU16162.1 - 6.5e-14 52.0 0.1 2.6e-10 40.2 0.0 2.0 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Peptidase_M16_C PF05193.21 OEU16163.1 - 3.6e-25 89.0 0.0 5.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OEU16163.1 - 4.6e-19 68.9 0.1 8.8e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FA_desaturase PF00487.24 OEU16164.1 - 6.6e-16 58.9 16.4 1e-15 58.3 16.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase FA_hydroxylase PF04116.13 OEU16164.1 - 0.3 11.5 12.8 0.59 10.5 0.6 2.4 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily DnaJ PF00226.31 OEU16165.1 - 2.4e-08 34.0 0.0 4.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain THDPS_N_2 PF14805.6 OEU16165.1 - 0.05 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PEP-utilisers_N PF05524.13 OEU16165.1 - 0.076 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TPR_2 PF07719.17 OEU16166.1 - 9e-05 22.3 4.5 0.81 10.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16166.1 - 0.0022 17.7 6.9 1.4 8.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat eIF3_subunit PF08597.10 OEU16166.1 - 0.084 12.8 7.4 0.037 13.9 4.8 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TPR_8 PF13181.6 OEU16166.1 - 0.12 12.7 2.5 33 5.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_7 PF12775.7 OEU16166.1 - 0.14 11.6 0.2 0.26 10.8 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region YL1 PF05764.13 OEU16166.1 - 5.3 7.1 9.4 7.9 6.5 9.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase PF00069.25 OEU16167.1 - 1.4e-48 165.5 0.0 1.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16167.1 - 4.2e-25 88.5 0.0 4.8e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU16167.1 - 4.6e-08 33.3 0.4 8.2e-08 32.5 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU16167.1 - 3.5e-07 29.8 0.1 2.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OEU16167.1 - 1.4e-06 27.3 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU16167.1 - 0.00019 20.8 0.4 0.0003 20.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OEU16167.1 - 0.0036 16.9 0.6 0.0046 16.6 0.6 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OEU16167.1 - 0.0044 16.7 1.5 0.0082 15.8 0.3 1.8 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 OEU16167.1 - 0.0084 15.7 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OEU16167.1 - 0.012 14.5 0.2 0.023 13.6 0.1 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Glyco_transf_8 PF01501.20 OEU16168.1 - 0.02 14.5 0.2 0.046 13.3 0.2 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 8 DUF2371 PF10177.9 OEU16168.1 - 0.27 11.4 0.1 0.27 11.4 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) TPR_12 PF13424.6 OEU16169.1 - 4.1e-37 126.3 17.3 2.9e-11 43.5 0.5 5.0 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU16169.1 - 8.4e-22 75.5 15.4 0.0022 18.0 0.1 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16169.1 - 1.5e-20 72.3 12.3 0.0038 17.0 0.3 8.2 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16169.1 - 2.8e-18 64.9 12.2 0.00051 19.8 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16169.1 - 9e-16 56.7 15.0 0.017 15.3 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 OEU16169.1 - 6.1e-12 45.0 9.3 0.13 12.0 0.1 8.2 7 3 2 9 9 9 2 TPR repeat TPR_7 PF13176.6 OEU16169.1 - 3e-10 39.4 12.7 0.72 10.0 0.1 7.5 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OEU16169.1 - 1.9e-08 34.4 5.2 12 7.0 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU16169.1 - 9.6e-08 32.6 4.5 1.6 9.5 0.0 6.6 5 3 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU16169.1 - 1.5e-07 31.1 0.1 0.00023 20.7 0.0 2.8 2 1 0 3 3 3 2 MalT-like TPR region DUF2225 PF09986.9 OEU16169.1 - 2.2e-05 24.3 3.8 0.003 17.3 0.3 2.7 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.9 OEU16169.1 - 4.4e-05 22.8 0.1 7 6.2 0.1 5.5 6 0 0 6 6 6 1 SHNi-TPR ANAPC3 PF12895.7 OEU16169.1 - 8e-05 22.8 3.8 0.051 13.8 0.1 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OEU16169.1 - 0.0003 21.2 6.2 9.4 7.1 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16169.1 - 0.00072 19.8 0.3 56 4.4 0.0 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU16169.1 - 0.0075 16.8 5.7 0.49 10.9 0.0 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat DUF5113 PF17140.4 OEU16169.1 - 0.014 15.2 3.7 4.8 7.0 0.1 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF5113) TPR_21 PF09976.9 OEU16169.1 - 0.028 14.1 1.3 6.3 6.5 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 OEU16169.1 - 0.038 14.6 3.6 26 5.8 0.0 4.7 6 0 0 6 6 3 0 Tetratricopeptide repeat MIT PF04212.18 OEU16169.1 - 0.093 12.8 11.9 4.6 7.4 0.3 4.8 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 OEU16169.1 - 0.11 12.7 2.2 11 6.4 0.1 3.2 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 DUF5093 PF17011.5 OEU16169.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) Sox_N PF12444.8 OEU16169.1 - 4 8.6 4.8 31 5.8 0.0 2.6 2 0 0 2 2 2 0 Sox developmental protein N terminal DUF357 PF04010.13 OEU16169.1 - 5.5 7.1 12.9 0.82 9.8 0.3 5.1 7 0 0 7 7 7 0 Protein of unknown function (DUF357) Pro_isomerase PF00160.21 OEU16170.1 - 2.2e-24 86.5 0.0 3.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4482 PF14818.6 OEU16170.1 - 0.025 15.5 3.0 0.039 14.8 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Effector_1 PF04518.12 OEU16170.1 - 0.1 11.7 1.5 0.16 11.0 1.5 1.2 1 0 0 1 1 1 0 Effector from type III secretion system PDZ PF00595.24 OEU16172.1 - 0.0035 17.7 0.0 0.0068 16.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU16172.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PulG PF11773.8 OEU16172.1 - 0.048 13.5 0.6 0.093 12.6 0.6 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin DUF4570 PF15134.6 OEU16172.1 - 0.11 12.5 2.0 0.18 11.9 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) PI-PLC-X PF00388.19 OEU16174.1 - 3e-53 179.3 0.0 2.8e-51 172.9 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OEU16174.1 - 7e-34 116.6 0.0 1.7e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OEU16174.1 - 7e-13 48.8 0.0 2.2e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 OEU16174.1 - 3.1e-05 23.2 0.0 0.0022 17.4 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OEU16174.1 - 7.4e-05 22.4 0.0 0.013 15.4 0.0 3.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OEU16174.1 - 0.0065 16.9 0.5 0.27 11.7 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU16174.1 - 0.033 13.7 0.2 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 EF hand Aminotran_3 PF00202.21 OEU16175.1 - 3.6e-121 404.6 0.0 4.3e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OEU16175.1 - 0.00026 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OEU16175.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF1207 PF06727.11 OEU16175.1 - 0.15 10.9 0.1 0.27 10.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) Peptidase_C1 PF00112.23 OEU16176.1 - 4.4e-36 125.0 0.0 5.5e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OEU16176.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family LRR_8 PF13855.6 OEU16177.1 - 0.053 13.3 0.2 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat EIF_2_alpha PF07541.12 OEU16177.1 - 0.087 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Endonuclease_7 PF02945.15 OEU16177.1 - 0.22 11.4 2.9 0.8 9.7 0.1 2.5 3 0 0 3 3 3 0 Recombination endonuclease VII LRR_6 PF13516.6 OEU16177.1 - 6.1 7.2 7.4 7.3 6.9 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat 2OG-FeII_Oxy_3 PF13640.6 OEU16178.1 - 4.8e-09 37.0 0.0 8.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU16178.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cas1_AcylT PF07779.12 OEU16180.1 - 6.3e-80 269.4 30.5 7.2e-80 269.2 30.5 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Methyltransf_22 PF13383.6 OEU16181.1 - 2e-06 27.5 0.0 3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OEU16181.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain SNARE_assoc PF09335.11 OEU16182.1 - 3.7e-24 85.5 7.7 5.1e-24 85.1 7.7 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein zf-C3HC4_3 PF13920.6 OEU16183.1 - 4.7e-08 32.8 11.5 7.4e-08 32.1 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU16183.1 - 2.1e-06 27.5 10.0 3.7e-06 26.7 10.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OEU16183.1 - 1.6e-05 25.1 11.8 2.9e-05 24.3 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OEU16183.1 - 5.4e-05 23.0 13.2 0.0001 22.1 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU16183.1 - 0.00011 22.0 12.1 0.00076 19.4 12.6 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OEU16183.1 - 0.00051 19.8 12.2 0.00093 19.0 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU16183.1 - 0.012 15.8 10.5 0.023 14.9 10.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TMF_TATA_bd PF12325.8 OEU16183.1 - 0.013 15.7 10.6 0.013 15.7 10.6 7.2 5 3 0 6 6 5 0 TATA element modulatory factor 1 TATA binding zf-RING_UBOX PF13445.6 OEU16183.1 - 0.016 15.2 9.6 0.033 14.2 9.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OEU16183.1 - 0.05 13.9 7.9 0.14 12.5 7.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OEU16183.1 - 0.085 12.7 8.9 0.18 11.6 8.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 OEU16183.1 - 0.15 12.1 4.8 0.4 10.8 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OEU16183.1 - 9.5 6.3 8.4 20 5.3 8.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 OEU16184.1 - 0.011 15.4 0.3 0.032 14.0 0.1 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 OEU16184.1 - 0.04 13.9 0.5 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RRN7 PF11781.8 OEU16184.1 - 0.13 12.0 0.4 0.31 10.8 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rubredoxin PF00301.20 OEU16184.1 - 0.18 11.8 1.7 1 9.5 1.7 2.1 1 1 0 1 1 1 0 Rubredoxin A2L_zn_ribbon PF08792.10 OEU16184.1 - 0.65 9.8 2.1 26 4.7 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_S30AE PF02482.19 OEU16185.1 - 1.3e-19 70.7 0.0 2.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 OEU16185.1 - 8.2e-16 57.4 0.8 1.9e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Sigma 54 modulation/S30EA ribosomal protein C terminus PRA-CH PF01502.18 OEU16185.1 - 0.06 13.2 0.7 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase CD99L2 PF12301.8 OEU16185.1 - 0.31 11.3 2.5 3.6 7.9 1.6 2.1 1 1 0 2 2 2 0 CD99 antigen like protein 2 Presenilin PF01080.17 OEU16186.1 - 1.4 7.6 8.1 2.2 7.0 8.1 1.2 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 OEU16187.1 - 1.2e-106 357.3 7.7 3.8e-105 352.3 9.0 2.5 2 1 0 2 2 2 1 Hsp70 protein Fer2 PF00111.27 OEU16188.1 - 1e-05 25.4 2.1 2.2e-05 24.3 2.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PDZ PF00595.24 OEU16188.1 - 0.0056 17.0 1.2 0.028 14.8 0.4 2.4 3 0 0 3 3 3 1 PDZ domain Fer2_4 PF13510.6 OEU16188.1 - 0.01 15.9 0.3 0.035 14.1 0.4 1.8 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain KTI12 PF08433.10 OEU16190.1 - 1.2e-09 38.1 3.4 4.8e-08 32.8 3.4 2.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OEU16190.1 - 1.1e-07 32.1 0.2 9.6e-07 29.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU16190.1 - 7.1e-06 26.6 2.1 2.2e-05 25.0 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU16190.1 - 0.00014 22.3 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 OEU16190.1 - 0.00023 21.1 0.1 0.0026 17.6 0.1 2.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein 6PF2K PF01591.18 OEU16190.1 - 0.00026 20.4 6.7 0.0014 18.0 0.1 3.1 3 2 0 3 3 3 1 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 OEU16190.1 - 0.0007 18.9 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 OEU16190.1 - 0.00073 19.5 0.0 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.6 OEU16190.1 - 0.002 18.4 0.2 0.0044 17.3 0.2 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 OEU16190.1 - 0.014 15.3 0.0 0.33 10.8 0.0 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase ThiP_synth PF10120.9 OEU16190.1 - 0.15 11.6 0.2 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Thiamine-phosphate synthase FlxA PF14282.6 OEU16190.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.8 4 0 0 4 4 4 0 FlxA-like protein His_biosynth PF00977.21 OEU16191.1 - 9.7e-26 90.6 0.1 5.5e-25 88.2 0.1 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein SR-25 PF10500.9 OEU16191.1 - 2.8 7.5 10.5 4.5 6.8 10.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OEU16191.1 - 2.9 8.6 8.7 5.9 7.6 8.7 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein RraB PF06877.11 OEU16192.1 - 0.017 15.8 0.2 0.043 14.5 0.2 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B DUF5055 PF16478.5 OEU16193.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5055) DDE_Tnp_1_7 PF13843.6 OEU16195.1 - 0.0002 20.8 0.2 0.00024 20.5 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 Tic110 PF16940.5 OEU16196.1 - 1.1e-06 27.4 0.0 0.00055 18.6 0.1 2.6 2 0 0 2 2 2 2 Chloroplast envelope transporter Tab2_like PF06485.11 OEU16196.1 - 0.095 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Glyco_hydro_47 PF01532.20 OEU16196.1 - 0.11 11.3 0.2 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 Chloroa_b-bind PF00504.21 OEU16197.1 - 1e-29 104.1 0.1 1.3e-29 103.8 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PGG PF13962.6 OEU16197.1 - 0.15 11.9 1.9 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function Enolase_C PF00113.22 OEU16198.1 - 1.2e-131 438.4 0.0 1.5e-131 438.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OEU16198.1 - 2e-56 189.7 0.1 3.5e-56 189.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OEU16198.1 - 2.8e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OEU16198.1 - 0.00048 19.4 1.0 0.0017 17.6 0.1 2.0 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Stealth_CR4 PF17103.5 OEU16199.1 - 0.14 12.1 3.4 0.19 11.7 2.0 1.8 1 1 1 2 2 2 0 Stealth protein CR4, conserved region 4 HEAT PF02985.22 OEU16200.1 - 1e-13 50.2 9.0 0.0037 17.4 0.2 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 OEU16200.1 - 5.6e-07 29.9 2.0 0.36 11.2 0.1 4.8 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 OEU16200.1 - 0.0054 17.2 8.7 0.095 13.2 0.4 4.9 5 1 0 5 5 5 1 HEAT-like repeat Ipi1_N PF12333.8 OEU16200.1 - 0.0056 17.3 0.0 0.026 15.1 0.0 2.1 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.8 OEU16200.1 - 0.006 16.2 0.5 2.9 7.4 0.0 3.4 3 1 1 4 4 4 2 CLASP N terminal UNC45-central PF11701.8 OEU16200.1 - 0.019 14.9 0.2 0.58 10.1 0.0 3.3 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 OEU16200.1 - 0.063 13.9 0.0 0.5 11.0 0.0 2.6 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region SNase PF00565.17 OEU16201.1 - 1.8e-39 134.5 0.0 7.8e-08 32.8 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OEU16201.1 - 5.2e-12 45.9 0.0 9.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 OEU16201.1 - 0.059 13.9 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 Agenet domain Fasciclin PF02469.22 OEU16202.1 - 1.9e-07 31.4 0.0 2.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Ribosomal_S10 PF00338.22 OEU16203.1 - 5.6e-27 93.8 0.3 6.6e-27 93.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 OEU16203.1 - 0.024 15.4 0.1 0.047 14.5 0.1 1.4 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Asp_Arg_Hydrox PF05118.15 OEU16204.1 - 0.016 15.0 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase Kinesin PF00225.23 OEU16205.1 - 3.1e-90 302.5 0.2 3.7e-90 302.2 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU16205.1 - 3.5e-33 114.6 0.0 8.4e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding BTB_2 PF02214.22 OEU16206.1 - 8.5e-17 61.3 0.0 2.6e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU16206.1 - 0.023 14.8 0.0 0.092 12.9 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain STT3 PF02516.14 OEU16207.1 - 5.3e-66 223.5 14.4 1.8e-65 221.7 14.4 1.7 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 OEU16208.1 - 3e-53 181.5 30.7 1.9e-52 178.8 30.7 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit AAA_2 PF07724.14 OEU16210.1 - 1.4e-53 181.5 0.0 7.7e-50 169.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OEU16210.1 - 6.4e-26 91.3 0.1 4.4e-14 53.0 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU16210.1 - 2.5e-18 66.4 0.6 9.9e-12 45.0 0.0 3.5 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU16210.1 - 5e-12 46.5 7.8 2.9e-06 27.8 0.1 5.8 5 1 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 OEU16210.1 - 9.1e-12 45.4 2.6 0.00048 20.4 0.5 4.4 3 2 0 3 3 2 2 AAA domain ClpB_D2-small PF10431.9 OEU16210.1 - 6.5e-11 42.1 0.0 2.6e-10 40.2 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 OEU16210.1 - 1e-09 38.3 0.1 6.2e-06 26.0 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 OEU16210.1 - 1.9e-08 33.9 0.0 0.00012 21.6 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 OEU16210.1 - 4.2e-08 32.9 0.1 0.02 14.4 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_14 PF13173.6 OEU16210.1 - 1.2e-06 28.6 0.0 0.018 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_lid_9 PF17871.1 OEU16210.1 - 1.3e-06 28.3 0.1 4.7e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain AAA_30 PF13604.6 OEU16210.1 - 2e-06 27.7 1.9 0.034 13.9 0.0 4.5 4 1 0 4 4 4 1 AAA domain TsaE PF02367.17 OEU16210.1 - 1.4e-05 25.1 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OEU16210.1 - 2.1e-05 25.1 0.8 0.041 14.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 OEU16210.1 - 3.3e-05 23.7 0.1 0.24 11.1 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.6 OEU16210.1 - 3.8e-05 24.0 0.7 0.017 15.4 0.1 3.9 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OEU16210.1 - 6.1e-05 23.4 0.5 0.38 11.2 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Clp_N PF02861.20 OEU16210.1 - 7.1e-05 22.9 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_33 PF13671.6 OEU16210.1 - 7.1e-05 23.0 0.5 0.12 12.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OEU16210.1 - 8.1e-05 22.1 0.2 3.1 7.1 0.1 3.7 2 2 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OEU16210.1 - 0.00011 22.0 0.0 0.075 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OEU16210.1 - 0.00014 21.5 1.4 0.45 10.1 0.0 3.3 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain ResIII PF04851.15 OEU16210.1 - 0.00015 21.8 1.3 0.32 11.0 0.0 3.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 OEU16210.1 - 0.00029 21.4 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter T2SSE PF00437.20 OEU16210.1 - 0.00038 19.6 0.3 0.68 8.9 0.0 2.6 2 1 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 OEU16210.1 - 0.00039 20.1 0.0 0.019 14.7 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OEU16210.1 - 0.00044 19.6 0.0 0.061 12.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 OEU16210.1 - 0.00047 20.4 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OEU16210.1 - 0.0005 20.6 0.8 0.21 12.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OEU16210.1 - 0.00064 19.7 0.1 0.031 14.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.13 OEU16210.1 - 0.0017 17.6 0.1 0.42 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 OEU16210.1 - 0.0017 18.3 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 OEU16210.1 - 0.0026 18.0 0.2 1.2 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OEU16210.1 - 0.0027 17.6 0.8 1.6 8.6 0.1 3.7 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea Torsin PF06309.11 OEU16210.1 - 0.0028 17.8 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Torsin PduV-EutP PF10662.9 OEU16210.1 - 0.0044 16.8 0.3 0.75 9.5 0.0 2.8 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OEU16210.1 - 0.0052 16.6 1.1 2.9 7.6 0.0 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein MCM PF00493.23 OEU16210.1 - 0.0093 15.1 1.8 0.28 10.2 0.1 3.3 3 1 0 3 3 3 1 MCM P-loop domain NTPase_1 PF03266.15 OEU16210.1 - 0.014 15.3 4.1 0.27 11.1 0.1 3.2 3 0 0 3 3 2 0 NTPase AAA_6 PF12774.7 OEU16210.1 - 0.017 14.1 2.9 0.017 14.1 0.1 2.3 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region NB-ARC PF00931.22 OEU16210.1 - 0.031 13.5 0.1 0.18 10.9 0.0 2.2 3 0 0 3 3 2 0 NB-ARC domain Rad17 PF03215.15 OEU16210.1 - 0.041 13.8 0.1 16 5.3 0.0 3.1 2 1 1 3 3 3 0 Rad17 P-loop domain Septin PF00735.18 OEU16210.1 - 0.048 12.9 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Septin DNA_pol3_delta2 PF13177.6 OEU16210.1 - 0.048 13.4 0.1 1.3 8.8 0.1 2.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit PhoH PF02562.16 OEU16210.1 - 0.068 12.6 0.0 13 5.2 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 OEU16210.1 - 0.17 11.0 0.1 19 4.2 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 EF-hand_1 PF00036.32 OEU16211.1 - 9.7e-08 31.0 1.6 0.00013 21.3 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU16211.1 - 2.1e-05 24.9 0.0 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OEU16211.1 - 5.4e-05 22.9 0.5 0.0013 18.6 0.2 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU16211.1 - 0.00023 20.5 2.9 0.00077 18.9 0.4 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OEU16211.1 - 0.00045 19.9 2.7 0.02 14.8 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain ABC1 PF03109.16 OEU16212.1 - 7e-19 68.2 0.0 2e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 ABC1 family Pkinase_Tyr PF07714.17 OEU16212.1 - 9.6e-08 31.6 0.0 0.00041 19.7 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OEU16212.1 - 9.4e-06 25.2 0.1 0.00018 20.9 0.0 2.5 2 1 1 3 3 3 1 Protein kinase domain RIO1 PF01163.22 OEU16212.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OEU16212.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HAD_2 PF13419.6 OEU16213.1 - 1.4e-08 35.0 0.0 1.8e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU16213.1 - 2.8e-06 27.8 0.0 9.7e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OEU16213.1 - 0.00016 21.5 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Acid Phosphatase Hydrolase_like PF13242.6 OEU16213.1 - 0.049 13.7 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 HAD-hyrolase-like NIF PF03031.18 OEU16213.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase CPBP PF02517.16 OEU16214.1 - 2.9e-05 24.4 2.1 2.9e-05 24.4 2.1 1.7 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Aa_trans PF01490.18 OEU16215.1 - 9.7e-37 126.6 21.2 1.3e-36 126.2 21.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 OEU16216.1 - 1.1e-44 152.8 27.9 1.4e-44 152.4 27.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 OEU16217.1 - 1.4e-42 145.9 26.1 1.7e-42 145.6 26.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5079 PF16882.5 OEU16217.1 - 0.032 14.1 0.8 0.085 12.7 0.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5079) TMEM125 PF15109.6 OEU16217.1 - 0.084 13.2 3.5 0.41 11.0 3.5 2.2 1 0 0 1 1 1 0 TMEM125 protein family SR-25 PF10500.9 OEU16218.1 - 0.0035 17.0 21.0 0.0035 17.0 21.0 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein ATP11 PF06644.11 OEU16218.1 - 0.15 11.9 10.6 0.038 13.8 7.0 1.8 1 1 1 2 2 2 0 ATP11 protein Presenilin PF01080.17 OEU16218.1 - 3 6.5 9.0 4.4 6.0 9.0 1.4 1 0 0 1 1 1 0 Presenilin DUF4315 PF14193.6 OEU16219.1 - 0.012 15.6 1.0 0.045 13.8 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Histone PF00125.24 OEU16220.1 - 1.4e-38 132.2 0.1 1.5e-38 132.1 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OEU16220.1 - 0.0018 18.6 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OEU16220.1 - 0.017 15.3 0.0 0.024 14.8 0.0 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold HMG-CoA_red PF00368.18 OEU16221.1 - 1.6e-79 267.6 9.1 1.7e-79 267.5 9.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Fe_bilin_red PF05996.12 OEU16222.1 - 0.0014 18.3 0.9 0.0014 18.3 0.9 1.8 2 0 0 2 2 2 1 Ferredoxin-dependent bilin reductase Metallothio_2 PF01439.18 OEU16222.1 - 0.028 15.3 3.3 1.2 10.1 0.1 3.1 2 1 0 2 2 2 0 Metallothionein DUF434 PF04256.12 OEU16222.1 - 0.16 11.7 0.5 6.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF434) Thioredoxin_8 PF13905.6 OEU16223.1 - 5.2e-14 52.3 0.0 6.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU16223.1 - 5.7e-05 22.9 0.1 8.2e-05 22.4 0.1 1.3 1 1 0 1 1 1 1 Redoxin DUF953 PF06110.11 OEU16223.1 - 0.00012 21.7 0.1 0.00048 19.7 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 OEU16223.1 - 0.00058 19.6 0.0 0.0074 16.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU16223.1 - 0.0089 16.5 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 OEU16223.1 - 0.13 12.2 0.5 0.97 9.5 0.2 2.1 1 1 0 2 2 2 0 Thioredoxin CoA_binding_2 PF13380.6 OEU16224.1 - 7.2e-23 81.3 0.0 1.2e-22 80.6 0.0 1.3 1 1 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 OEU16224.1 - 0.003 18.2 0.0 0.0042 17.7 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain DnaB PF00772.21 OEU16224.1 - 0.052 13.6 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Ank_2 PF12796.7 OEU16225.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Mac PF12464.8 OEU16226.1 - 6.5e-14 51.9 0.2 1e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 OEU16226.1 - 1.4e-13 50.0 14.1 5.3e-12 45.0 4.8 3.3 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OEU16226.1 - 1.4e-13 50.3 14.2 2.5e-13 49.5 4.2 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Sugar_tr PF00083.24 OEU16227.1 - 1.8e-81 274.3 28.1 2.1e-81 274.1 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU16227.1 - 1.9e-25 89.5 25.3 1.9e-25 89.5 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YabA PF06156.13 OEU16228.1 - 0.58 10.8 2.7 1.7 9.3 2.7 1.7 1 0 0 1 1 1 0 Initiation control protein YabA MFS_1 PF07690.16 OEU16229.1 - 5.7e-23 81.4 38.8 3.8e-15 55.7 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU16229.1 - 1.7e-22 79.9 21.6 4.3e-19 68.7 9.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 OEU16229.1 - 1.2e-05 23.9 15.6 4.4e-05 22.1 5.9 3.1 2 1 1 3 3 3 3 Transmembrane secretion effector FixP_N PF14715.6 OEU16229.1 - 0.31 10.8 2.2 1.3 8.9 2.2 2.1 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP HECT PF00632.25 OEU16231.1 - 2.2e-45 155.5 0.0 3.9e-40 138.2 0.0 2.1 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Creatininase PF02633.14 OEU16231.1 - 0.034 13.6 0.1 9.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Creatinine amidohydrolase DUF1970 PF09301.10 OEU16231.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Acid_PPase PF12689.7 OEU16232.1 - 6.8e-25 87.9 0.0 9.5e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 OEU16232.1 - 0.013 15.8 0.0 0.22 11.8 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OEU16232.1 - 0.091 12.8 0.3 4.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase ATP12 PF07542.11 OEU16233.1 - 8.4e-25 87.3 0.3 3.5e-24 85.3 0.3 1.9 1 1 0 1 1 1 1 ATP12 chaperone protein SF-assemblin PF06705.11 OEU16234.1 - 1.3e-21 77.1 26.9 1.5e-21 76.9 26.9 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Toast_rack_N PF17115.5 OEU16234.1 - 0.043 14.1 2.2 0.082 13.2 0.1 2.3 2 1 0 2 2 2 0 N-terminal domain of toast_rack, DUF2154 DUF1599 PF07659.11 OEU16234.1 - 0.076 13.5 0.7 12 6.4 0.0 3.0 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 Minor_tail_Z PF06763.11 OEU16234.1 - 0.094 12.5 5.6 3 7.6 1.8 2.5 2 1 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Seadorna_VP6 PF07407.11 OEU16234.1 - 0.15 11.0 7.2 0.17 10.8 7.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Baculo_PEP_C PF04513.12 OEU16234.1 - 0.23 11.5 10.1 0.14 12.2 0.7 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Hsk3 PF08227.11 OEU16234.1 - 0.24 11.8 4.5 0.65 10.4 0.3 3.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like NuA4 PF09340.10 OEU16234.1 - 3.1 7.7 7.0 4 7.4 0.2 3.1 3 2 0 3 3 3 0 Histone acetyltransferase subunit NuA4 ORF6C PF10552.9 OEU16234.1 - 6.9 6.8 11.3 4.3 7.5 0.9 2.9 3 0 0 3 3 3 0 ORF6C domain DUF1279 PF06916.13 OEU16235.1 - 2.1e-09 37.8 0.3 9.5e-09 35.7 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MatE PF01554.18 OEU16236.1 - 1.2e-28 99.8 27.3 4.7e-15 55.6 6.1 3.9 3 1 1 4 4 4 2 MatE WW PF00397.26 OEU16236.1 - 1.7e-05 24.8 0.5 3.5e-05 23.8 0.5 1.6 1 0 0 1 1 1 1 WW domain YrhC PF14143.6 OEU16236.1 - 0.015 15.3 0.2 0.015 15.3 0.2 2.7 3 0 0 3 3 3 0 YrhC-like protein CclA_1 PF16942.5 OEU16236.1 - 6.2 7.2 10.4 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Putative cyclic bacteriocin adh_short PF00106.25 OEU16237.1 - 3.7e-29 101.6 0.0 1.9e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU16237.1 - 1.3e-19 70.7 0.0 1.6e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU16237.1 - 0.0088 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 KR domain SRP40_C PF05022.12 OEU16238.1 - 2.4e-18 66.7 3.9 7.9e-18 65.1 3.9 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Peptidase_S9 PF00326.21 OEU16239.1 - 1.7e-52 178.0 0.0 2.3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family EAP30 PF04157.16 OEU16240.1 - 1.2e-21 77.1 0.2 2.1e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family RCC1 PF00415.18 OEU16241.1 - 4e-31 107.4 23.3 6.4e-12 45.9 0.1 7.8 6 3 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU16241.1 - 2.7e-21 74.8 17.0 9.8e-06 25.2 0.0 6.4 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat 5_nucleotid_C PF02872.18 OEU16242.1 - 2.4e-28 99.3 0.0 1.4e-13 51.4 0.0 2.4 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain DUF5383 PF17355.2 OEU16242.1 - 2.9 8.3 4.8 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) LIN37 PF15306.6 OEU16242.1 - 5.9 7.1 12.4 0.038 14.2 3.2 2.0 2 1 0 2 2 2 0 LIN37 SR-25 PF10500.9 OEU16243.1 - 0.0034 17.0 20.1 0.0034 17.0 20.1 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.10 OEU16243.1 - 5.1 5.6 6.4 7.6 5.1 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 OEU16243.1 - 8.6 5.1 8.5 13 4.4 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_transf_8 PF01501.20 OEU16244.1 - 8.9e-05 22.2 0.7 0.0047 16.5 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OEU16244.1 - 0.0058 16.0 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative DUF2721 PF11026.8 OEU16244.1 - 0.084 12.8 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) 120_Rick_ant PF12574.8 OEU16244.1 - 0.11 11.6 0.4 0.2 10.9 0.4 1.3 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen C2 PF00168.30 OEU16246.1 - 0.00012 22.3 0.2 0.00064 20.0 0.0 2.3 3 0 0 3 3 3 1 C2 domain Tli4_C PF18426.1 OEU16246.1 - 0.078 13.3 1.0 0.75 10.1 0.0 2.8 2 1 1 3 3 3 0 Tle cognate immunity protein 4 C-terminal domain DUF604 PF04646.12 OEU16246.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 AAA PF00004.29 OEU16247.1 - 3.7e-24 85.6 0.0 4.7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OEU16247.1 - 4.3e-05 23.5 0.2 0.23 11.4 0.0 2.2 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 OEU16247.1 - 0.00011 22.5 0.2 0.033 14.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 OEU16247.1 - 0.0003 21.2 0.3 0.0041 17.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OEU16247.1 - 0.0011 19.2 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU16247.1 - 0.0016 18.4 0.1 0.0079 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OEU16247.1 - 0.003 17.8 0.3 0.021 15.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OEU16247.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 OEU16247.1 - 0.016 14.8 0.1 0.21 11.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 OEU16247.1 - 0.017 15.1 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OEU16247.1 - 0.019 15.5 0.0 0.036 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OEU16247.1 - 0.02 14.6 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 OEU16247.1 - 0.03 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 OEU16247.1 - 0.034 13.9 0.1 0.059 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OEU16247.1 - 0.054 12.9 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OEU16247.1 - 0.056 13.2 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 OEU16247.1 - 0.071 13.0 0.0 1 9.3 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OEU16247.1 - 0.082 13.3 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 OEU16247.1 - 0.084 11.9 0.4 0.44 9.6 0.1 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 OEU16247.1 - 0.11 12.9 0.5 0.16 12.3 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OEU16247.1 - 0.11 12.2 0.3 0.18 11.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OEU16247.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OEU16247.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 OEU16249.1 - 2.1e-11 44.1 2.4 4.6e-11 43.0 2.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU16249.1 - 9.1e-11 40.5 0.6 0.00016 21.0 0.1 2.6 2 0 0 2 2 2 2 EF hand Na_Ca_ex PF01699.24 OEU16249.1 - 2.5e-08 34.0 30.0 1.9e-07 31.2 13.0 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_6 PF13405.6 OEU16249.1 - 6.4e-07 28.8 7.7 4.4e-05 23.1 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OEU16249.1 - 2.8e-06 26.6 0.4 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OEU16249.1 - 0.0011 18.8 2.2 0.0073 16.1 1.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU16249.1 - 0.051 13.9 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PCIF1_WW PF12237.8 OEU16250.1 - 3e-57 193.0 1.1 3.6e-57 192.7 1.1 1.1 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Herpes_LMP2 PF07415.11 OEU16251.1 - 0.0054 15.6 1.6 0.0068 15.2 1.6 1.2 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein CPSase_L_D2 PF02786.17 OEU16252.1 - 3.1e-112 373.2 0.2 2.3e-81 272.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OEU16252.1 - 2.9e-50 169.4 0.0 6.9e-50 168.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OEU16252.1 - 2e-41 141.8 0.0 1.3e-40 139.2 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OEU16252.1 - 6.7e-37 126.5 0.1 1.9e-36 125.1 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OEU16252.1 - 1.3e-16 60.6 0.0 3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OEU16252.1 - 1.2e-15 57.6 0.1 8.7e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 OEU16252.1 - 1.9e-15 56.8 0.0 9.1e-15 54.6 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 OEU16252.1 - 7.1e-11 42.0 0.0 0.00024 20.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OEU16252.1 - 5.8e-06 26.4 0.0 0.006 16.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 OEU16252.1 - 0.00033 20.5 0.2 0.013 15.2 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 OEU16252.1 - 0.028 14.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 OEU16252.1 - 0.07 12.6 0.0 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain HA PF03457.14 OEU16253.1 - 5.6e-40 135.5 19.1 2.5e-14 53.3 0.3 3.5 4 0 0 4 4 4 3 Helicase associated domain PhoD PF09423.10 OEU16254.1 - 2.2e-13 49.9 0.0 1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Mpv17_PMP22 PF04117.12 OEU16255.1 - 5.1e-14 52.3 3.1 9.1e-14 51.4 0.1 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family TPR_12 PF13424.6 OEU16256.1 - 2e-49 165.8 13.4 1.2e-12 47.9 0.2 4.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16256.1 - 2.1e-23 81.4 6.7 0.00076 19.3 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU16256.1 - 6.5e-21 72.7 10.6 0.0048 16.9 0.1 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16256.1 - 2.8e-16 58.5 10.0 0.0014 18.3 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU16256.1 - 5.9e-15 55.5 1.5 9.6e-06 25.2 0.0 3.1 1 1 1 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 OEU16256.1 - 1.1e-12 47.0 8.0 0.15 12.2 0.1 6.9 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OEU16256.1 - 3.6e-08 33.8 3.0 0.023 15.2 0.1 5.6 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16256.1 - 1.1e-05 25.3 9.4 4.3 7.8 0.1 6.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU16256.1 - 1.8e-05 25.2 7.5 18 6.5 0.0 6.9 4 3 3 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU16256.1 - 3.4e-05 24.4 4.7 19 6.0 0.1 6.4 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16256.1 - 0.00011 22.3 0.0 7.7 7.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU16256.1 - 0.00021 21.5 6.2 0.2 11.9 0.1 5.1 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OEU16256.1 - 0.00023 21.2 7.7 2 8.9 0.1 5.8 6 1 1 7 7 6 2 PPR repeat TPR_11 PF13414.6 OEU16256.1 - 0.00062 19.4 4.0 3.9 7.3 0.0 5.6 7 0 0 7 7 7 1 TPR repeat MIT PF04212.18 OEU16256.1 - 0.0007 19.6 9.0 12 6.1 0.0 5.9 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 OEU16256.1 - 0.0026 17.2 3.2 0.3 10.5 0.3 3.3 1 1 2 3 3 3 1 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 OEU16256.1 - 0.0048 16.3 0.3 0.57 9.6 0.1 2.5 2 0 0 2 2 2 1 Coatomer epsilon subunit RPN7 PF10602.9 OEU16256.1 - 0.045 13.5 3.1 2.9 7.6 0.1 3.7 2 2 0 3 3 3 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 OEU16256.1 - 0.08 12.4 0.1 2.5 7.6 0.0 3.5 5 0 0 5 5 5 0 SHNi-TPR TPR_4 PF07721.14 OEU16256.1 - 0.092 13.4 2.4 1.4e+02 3.6 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 OEU16256.1 - 0.094 12.4 0.7 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain DUF5113 PF17140.4 OEU16256.1 - 0.098 12.5 3.1 15 5.4 0.1 3.9 3 2 2 5 5 4 0 Domain of unknown function (DUF5113) TPR_15 PF13429.6 OEU16256.1 - 0.1 11.8 0.1 8.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Brix PF04427.18 OEU16257.1 - 1.8e-18 67.3 0.1 2e-18 67.2 0.1 1.0 1 0 0 1 1 1 1 Brix domain Adaptin_N PF01602.20 OEU16258.1 - 2.1e-80 270.8 3.8 3.1e-80 270.2 3.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 OEU16258.1 - 7.8e-56 187.5 0.1 1.7e-55 186.4 0.1 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 OEU16258.1 - 7.9e-49 165.2 0.0 1.8e-48 164.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 OEU16258.1 - 2.9e-09 37.2 1.8 1.9e-06 28.0 0.0 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OEU16258.1 - 5.9e-07 29.8 0.9 0.59 10.6 0.0 5.9 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.22 OEU16258.1 - 4e-06 26.6 1.4 0.22 11.9 0.0 5.7 5 1 1 6 6 6 2 HEAT repeat Coatomer_g_Cpla PF16381.5 OEU16258.1 - 1.1e-05 25.6 0.3 5e-05 23.4 0.0 2.4 3 0 0 3 3 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Arm PF00514.23 OEU16258.1 - 0.0041 17.1 0.3 1.4 9.0 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ERAP1_C PF11838.8 OEU16258.1 - 0.037 13.6 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 ERAP1-like C-terminal domain HEAT_EZ PF13513.6 OEU16258.1 - 0.069 13.7 2.2 24 5.5 0.0 5.4 4 3 2 6 6 6 0 HEAT-like repeat DUF4747 PF15931.5 OEU16258.1 - 0.11 12.2 0.2 0.27 10.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4747) DUF3730 PF12530.8 OEU16258.1 - 0.11 12.0 2.7 2.6 7.6 3.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3730) V-ATPase_H_C PF11698.8 OEU16258.1 - 0.13 12.4 0.5 12 6.1 0.0 3.8 3 1 0 4 4 4 0 V-ATPase subunit H Sigma70_r4 PF04545.16 OEU16259.1 - 7.9e-20 70.1 9.2 6.4e-19 67.2 2.0 3.2 4 0 0 4 4 4 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 OEU16259.1 - 2.6e-19 68.8 0.1 6.4e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 OEU16259.1 - 3.3e-11 43.1 3.5 2.9e-09 36.9 0.1 3.5 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 OEU16259.1 - 0.00015 21.7 0.0 0.0004 20.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 SLIDE PF09111.10 OEU16259.1 - 0.006 16.6 0.9 0.047 13.7 0.4 2.5 2 0 0 2 2 2 1 SLIDE PPR_2 PF13041.6 OEU16260.1 - 8.9e-16 57.8 2.4 0.00034 20.8 0.1 7.2 5 3 2 7 7 7 4 PPR repeat family PPR_3 PF13812.6 OEU16260.1 - 1.7e-13 50.4 0.3 0.14 12.3 0.0 7.2 4 2 3 7 7 7 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU16260.1 - 5.1e-09 35.7 14.8 0.012 15.3 0.0 9.3 10 0 0 10 10 10 2 PPR repeat PPR PF01535.20 OEU16260.1 - 5e-05 23.3 14.4 0.81 10.1 0.6 9.1 10 2 0 10 10 10 1 PPR repeat PPR_long PF17177.4 OEU16260.1 - 0.00044 19.7 2.4 0.012 15.0 0.6 2.6 1 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP Cadherin_pro PF08758.11 OEU16261.1 - 0.023 14.8 0.1 0.057 13.6 0.1 1.7 1 0 0 1 1 1 0 Cadherin prodomain like Na_H_Exchanger PF00999.21 OEU16262.1 - 8.2e-47 159.8 43.2 1.2e-46 159.3 43.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1104 PF06518.11 OEU16262.1 - 0.19 12.1 2.7 0.56 10.6 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Acetyltransf_1 PF00583.25 OEU16263.1 - 3.6e-12 46.6 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU16263.1 - 3.1e-09 37.1 0.0 4.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU16263.1 - 3.4e-09 36.7 0.0 6.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU16263.1 - 9.4e-09 35.1 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OEU16263.1 - 0.0023 18.6 0.0 0.0029 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NMT PF01233.19 OEU16263.1 - 0.008 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_CG PF14542.6 OEU16263.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OEU16263.1 - 0.059 13.5 0.0 0.077 13.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OEU16263.1 - 0.061 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 OEU16263.1 - 0.077 12.4 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF4336 PF14234.6 OEU16264.1 - 8.4e-110 366.9 0.1 9.6e-110 366.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) DUF3755 PF12579.8 OEU16264.1 - 0.41 10.3 0.0 0.41 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) Inhibitor_I53 PF11714.8 OEU16265.1 - 0.093 12.9 0.3 0.093 12.9 0.3 2.1 2 1 0 2 2 2 0 Thrombin inhibitor Madanin Vps54 PF07928.12 OEU16266.1 - 1e-35 123.1 1.8 1e-35 123.1 1.8 2.7 2 0 0 2 2 2 1 Vps54-like protein Sec8_exocyst PF04048.14 OEU16266.1 - 0.0013 18.6 0.9 0.0013 18.6 0.9 2.8 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain MCC-bdg_PDZ PF10506.9 OEU16266.1 - 0.21 11.6 4.5 2.2 8.4 0.2 3.3 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome IPK PF03770.16 OEU16266.1 - 8.2 6.2 7.6 1.3 8.8 1.7 2.4 2 1 0 2 2 2 0 Inositol polyphosphate kinase MTS PF05175.14 OEU16267.1 - 2.4e-08 33.7 0.1 1.3e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OEU16267.1 - 1.4e-07 31.3 0.0 4.4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OEU16267.1 - 0.00081 20.0 0.0 0.0025 18.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU16267.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16267.1 - 0.095 12.5 0.0 0.41 10.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain TPR_14 PF13428.6 OEU16267.1 - 0.19 12.7 0.0 0.62 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat VEG PF06257.11 OEU16268.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Biofilm formation stimulator VEG DUF2057 PF09829.9 OEU16268.1 - 0.3 11.2 4.2 0.14 12.3 0.8 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Ribosomal_L22 PF00237.19 OEU16269.1 - 9.5e-17 61.1 0.4 2.3e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e TTL PF03133.15 OEU16270.1 - 1.4e-07 30.9 0.5 2.5e-07 30.2 0.5 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Amidohydro_2 PF04909.14 OEU16271.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 1 1 2 2 2 1 Amidohydrolase GHL6 PF14871.6 OEU16271.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 WD40 PF00400.32 OEU16273.1 - 0.00038 21.2 0.1 13 6.8 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Mpv17_PMP22 PF04117.12 OEU16274.1 - 2.5e-11 43.6 1.0 2.5e-11 43.6 1.0 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Pex14_N PF04695.13 OEU16274.1 - 3.5 8.3 7.1 0.31 11.7 2.5 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asn_synthase PF00733.21 OEU16276.1 - 1.4e-66 225.6 0.2 4.5e-42 145.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OEU16276.1 - 7.5e-24 84.0 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OEU16276.1 - 1.3e-20 74.0 0.0 2.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OEU16276.1 - 0.0001 21.9 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein Chloroa_b-bind PF00504.21 OEU16277.1 - 1.2e-21 77.9 0.1 2.4e-21 77.0 0.1 1.5 1 1 0 1 1 1 1 Chlorophyll A-B binding protein DPPIV_N PF00930.21 OEU16278.1 - 1.5e-61 208.1 0.0 5.5e-60 203.0 0.0 2.6 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OEU16278.1 - 6.9e-55 185.8 0.0 2.3e-54 184.1 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OEU16278.1 - 1.2e-08 34.9 0.4 1.2e-06 28.3 0.0 3.0 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OEU16278.1 - 0.00022 20.9 0.0 0.00066 19.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OEU16278.1 - 0.00094 19.8 1.1 0.00094 19.8 1.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.14 OEU16278.1 - 0.0025 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Esterase_phd PF10503.9 OEU16278.1 - 0.0068 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 OEU16278.1 - 0.022 14.0 0.4 0.52 9.5 0.1 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 RVT_3 PF13456.6 OEU16278.1 - 0.029 14.2 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Abhydrolase_3 PF07859.13 OEU16278.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3141 PF11339.8 OEU16278.1 - 0.094 11.1 0.2 0.16 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) COPI_assoc PF08507.10 OEU16279.1 - 8.9e-14 51.7 7.4 1.1e-13 51.4 7.4 1.1 1 0 0 1 1 1 1 COPI associated protein pKID PF02173.17 OEU16279.1 - 0.033 13.7 0.3 0.057 12.9 0.3 1.3 1 0 0 1 1 1 0 pKID domain Ion_trans PF00520.31 OEU16280.1 - 2.7e-08 33.4 2.1 2.7e-08 33.4 2.1 1.4 2 0 0 2 2 2 1 Ion transport protein Linker_histone PF00538.19 OEU16283.1 - 1.9e-11 44.2 0.6 9.9e-11 41.9 0.6 2.3 1 0 0 1 1 1 1 linker histone H1 and H5 family WSD PF15613.6 OEU16283.1 - 1.9e-06 28.2 0.0 1.9e-06 28.2 0.0 4.0 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PWWP PF00855.17 OEU16283.1 - 8.8e-06 26.0 0.0 8.8e-06 26.0 0.0 4.5 5 0 0 5 5 5 1 PWWP domain Toxin_10 PF05431.11 OEU16284.1 - 0.087 12.3 0.3 0.18 11.3 0.3 1.5 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Synaptobrevin PF00957.21 OEU16285.1 - 1.3e-09 37.7 7.7 3.7e-09 36.2 7.7 1.8 1 0 0 1 1 1 1 Synaptobrevin Ank_3 PF13606.6 OEU16285.1 - 0.00058 20.1 0.0 0.0039 17.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OEU16285.1 - 0.00086 19.6 0.0 0.0032 17.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU16285.1 - 0.0057 17.2 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU16285.1 - 0.013 16.1 0.0 0.036 14.7 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OEU16285.1 - 0.046 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat HSF_DNA-bind PF00447.17 OEU16287.1 - 4.4e-06 27.2 0.2 5.9e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding MatE PF01554.18 OEU16288.1 - 1.3e-17 63.9 21.2 1.2e-14 54.3 6.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU16288.1 - 3.3e-08 33.7 6.0 3.3e-08 33.7 6.0 3.3 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain HSP70 PF00012.20 OEU16289.1 - 3.5e-09 35.4 0.4 0.013 13.8 0.1 3.1 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 OEU16289.1 - 0.068 12.0 0.1 1.2 7.9 0.1 2.3 2 0 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.25 OEU16290.1 - 5.5e-58 196.4 0.0 6.1e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16290.1 - 1.2e-36 126.3 0.1 2.1e-36 125.5 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU16290.1 - 4.7e-06 26.1 0.0 1.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OEU16290.1 - 2.1e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 OEU16290.1 - 0.0039 17.4 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF5602 PF18197.1 OEU16292.1 - 0.046 14.2 0.1 0.63 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5602) Agenet PF05641.12 OEU16293.1 - 0.082 13.4 2.7 0.11 13.0 0.2 2.6 2 0 0 2 2 2 0 Agenet domain AMPK1_CBM PF16561.5 OEU16294.1 - 1e-33 115.4 0.2 2.3e-33 114.2 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 OEU16294.1 - 3.2e-25 88.2 5.4 5.8e-25 87.4 5.4 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CSD PF00313.22 OEU16295.1 - 2.9e-26 91.1 0.1 3.8e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU16295.1 - 2.8e-05 23.7 0.2 4.9e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain Cupin_8 PF13621.6 OEU16296.1 - 1.7 8.3 6.9 2.6 7.7 0.0 2.1 1 1 0 2 2 2 0 Cupin-like domain Atrophin-1 PF03154.15 OEU16296.1 - 1.9 6.6 15.1 3.2 5.9 15.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family Imm5 PF14423.6 OEU16296.1 - 2.1 8.5 9.4 3.5 7.8 2.4 2.3 2 0 0 2 2 2 0 Immunity protein Imm5 BAF1_ABF1 PF04684.13 OEU16296.1 - 2.4 7.1 18.8 1.5 7.7 11.9 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TAF4 PF05236.14 OEU16296.1 - 2.6 7.7 19.9 0.097 12.4 12.8 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Cwf_Cwc_15 PF04889.12 OEU16296.1 - 2.7 7.7 22.5 0.1 12.3 0.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein eIF3_subunit PF08597.10 OEU16296.1 - 5.3 6.9 31.2 0.23 11.4 16.7 2.4 2 1 0 2 2 2 0 Translation initiation factor eIF3 subunit DDRGK PF09756.9 OEU16296.1 - 6.9 6.2 22.2 0.28 10.8 15.5 1.9 2 0 0 2 2 2 0 DDRGK domain Drc1-Sld2 PF11719.8 OEU16297.1 - 0.9 9.0 18.9 1.2 8.5 18.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Glyco_transf_6 PF03414.13 OEU16298.1 - 0.061 12.1 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 Ccdc124 PF06244.12 OEU16299.1 - 5.8e-19 68.9 19.9 4.2e-17 62.9 19.9 2.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 OEU16299.1 - 0.032 14.6 0.2 0.032 14.6 0.2 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box UQ_con PF00179.26 OEU16300.1 - 1e-48 164.5 0.0 1.2e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU16300.1 - 0.00086 19.0 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OEU16300.1 - 0.039 13.8 0.1 0.085 12.7 0.1 1.5 1 1 0 1 1 1 0 UEV domain ArgJ PF01960.18 OEU16302.1 - 3.9e-107 358.2 0.1 4.8e-107 357.9 0.1 1.0 1 0 0 1 1 1 1 ArgJ family MutS_III PF05192.18 OEU16303.1 - 1 9.5 5.0 1.5 9.0 5.0 1.3 1 0 0 1 1 1 0 MutS domain III zf-RING_11 PF17123.5 OEU16304.1 - 5e-06 26.2 4.7 5e-06 26.2 4.7 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 OEU16304.1 - 6.1e-06 26.5 2.5 6.1e-06 26.5 2.5 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OEU16304.1 - 0.00011 21.9 2.0 0.00011 21.9 2.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU16304.1 - 0.00015 21.7 0.6 0.00015 21.7 0.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OEU16304.1 - 0.0006 19.9 2.5 0.0006 19.9 2.5 2.1 2 0 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OEU16304.1 - 0.00092 19.2 3.8 0.0024 17.9 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OEU16304.1 - 0.005 16.7 2.4 0.005 16.7 2.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU16304.1 - 0.012 15.9 4.8 0.012 15.9 4.8 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 OEU16304.1 - 0.1 12.3 5.1 0.33 10.6 5.1 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-LITAF-like PF10601.9 OEU16304.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.0 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain TP_methylase PF00590.20 OEU16305.1 - 8.6e-43 146.8 0.0 1.1e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Fer2_3 PF13085.6 OEU16306.1 - 0.00076 19.5 0.2 0.0013 18.8 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 OEU16306.1 - 0.0019 18.1 0.1 0.0025 17.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ATP-synt PF00231.19 OEU16307.1 - 5.3e-84 282.2 0.5 6.1e-84 282.0 0.5 1.0 1 0 0 1 1 1 1 ATP synthase Pox_P4A PF03395.14 OEU16308.1 - 0.015 12.9 0.2 0.02 12.5 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein BRCT_2 PF16589.5 OEU16308.1 - 0.086 13.3 0.2 0.24 11.8 0.2 1.9 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain zf-C2H2_10 PF16588.5 OEU16308.1 - 0.68 9.7 3.8 0.38 10.5 0.6 2.0 1 1 1 2 2 2 0 C2H2 zinc-finger PH_4 PF15404.6 OEU16309.1 - 6.1 6.6 9.8 0.84 9.4 0.1 2.8 1 1 1 3 3 3 0 Pleckstrin homology domain Nucleo_P87 PF07267.11 OEU16310.1 - 2.5 6.9 8.0 3.6 6.3 8.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 KH_6 PF15985.5 OEU16311.1 - 2.5e-10 40.5 0.0 4.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 KH domain FapA PF03961.13 OEU16311.1 - 0.042 12.5 0.3 0.066 11.8 0.0 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A SPRY PF00622.28 OEU16311.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 SPRY domain UNC-50 PF05216.13 OEU16313.1 - 1.7e-67 227.3 13.8 1.9e-67 227.1 13.8 1.0 1 0 0 1 1 1 1 UNC-50 family zinc_ribbon_6 PF14599.6 OEU16314.1 - 1.2e-18 66.9 0.7 1.2e-18 66.9 0.7 4.2 2 1 2 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 OEU16314.1 - 1e-15 58.0 17.6 1e-15 58.0 17.6 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 OEU16314.1 - 1.8e-09 37.8 6.1 1.8e-09 37.8 6.1 5.5 3 2 3 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 OEU16314.1 - 6.9e-07 29.1 5.5 6.9e-07 29.1 5.5 5.9 4 3 1 5 5 5 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU16314.1 - 0.00017 21.5 1.5 0.00017 21.5 1.5 4.9 5 2 1 6 6 6 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OEU16314.1 - 0.00049 19.9 2.1 0.00049 19.9 2.1 5.8 4 3 1 5 5 5 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OEU16314.1 - 0.004 16.9 8.1 0.004 16.9 8.1 6.3 5 3 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU16314.1 - 0.0044 16.8 8.5 0.0044 16.8 8.5 6.8 3 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Clat_adaptor_s PF01217.20 OEU16315.1 - 1.1e-41 142.1 0.4 1.2e-41 142.0 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sorb PF02208.16 OEU16316.1 - 0.031 14.1 0.2 0.074 12.9 0.2 1.6 1 0 0 1 1 1 0 Sorbin homologous domain SR-25 PF10500.9 OEU16316.1 - 0.05 13.2 11.0 0.056 13.0 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 OEU16316.1 - 0.27 9.7 12.0 0.3 9.6 12.0 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OEU16316.1 - 0.33 9.7 6.5 0.35 9.6 6.5 1.0 1 0 0 1 1 1 0 Presenilin Tubulin PF00091.25 OEU16317.1 - 2.8e-66 223.5 0.0 4.1e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OEU16317.1 - 6.4e-50 168.5 0.0 9.8e-50 167.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OEU16317.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain FGGY_C PF02782.16 OEU16318.1 - 9.3e-37 126.7 0.0 1.4e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OEU16318.1 - 4.4e-30 105.0 0.0 1.1e-28 100.5 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3446 PF11928.8 OEU16318.1 - 0.0011 19.2 1.5 0.0027 18.0 1.5 1.6 1 0 0 1 1 1 1 Early growth response N-terminal domain ODV-E18 PF10717.9 OEU16318.1 - 0.067 13.1 0.9 0.15 12.0 0.9 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Aldedh PF00171.22 OEU16319.1 - 9.8e-170 565.0 0.0 1.1e-169 564.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ATPgrasp_ST PF14397.6 OEU16320.1 - 4.3e-07 29.5 0.0 0.00016 21.0 0.0 2.8 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp RNA_pol_L_2 PF13656.6 OEU16321.1 - 5.8e-29 99.7 0.0 7.8e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OEU16321.1 - 1.6e-11 43.5 0.0 2.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4530 PF15039.6 OEU16321.1 - 0.0099 16.0 1.5 0.014 15.5 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) CENP-B_dimeris PF09026.10 OEU16321.1 - 0.078 13.4 5.9 0.14 12.6 5.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SPC25 PF06703.11 OEU16323.1 - 0.04 13.7 0.6 0.5 10.1 0.0 2.6 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Cadherin_C_2 PF16492.5 OEU16323.1 - 0.058 14.1 1.5 0.3 11.9 1.5 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Diphthami_syn_2 PF01902.17 OEU16324.1 - 2e-30 106.0 0.1 9.8e-29 100.4 0.1 2.7 1 1 0 1 1 1 1 Diphthamide synthase tRNA-synt_2e PF02091.15 OEU16324.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit CCDC53 PF10152.9 OEU16325.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Glyco_transf_10 PF00852.19 OEU16326.1 - 2e-28 99.3 0.3 2.8e-28 98.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF4800 PF16057.5 OEU16326.1 - 0.084 12.1 0.0 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Blt1_C PF17183.4 OEU16326.1 - 0.19 11.4 0.6 0.4 10.3 0.6 1.5 1 0 0 1 1 1 0 Get5 carboxyl domain zf-NOSIP PF15906.5 OEU16327.1 - 1.3e-12 47.7 0.0 3.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 OEU16327.1 - 0.0019 17.6 10.7 0.079 12.3 4.8 2.8 2 1 1 3 3 3 2 Rtf2 RING-finger DUF2093 PF09866.9 OEU16327.1 - 0.0054 16.2 0.1 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2093) U-box PF04564.15 OEU16327.1 - 0.01 16.0 0.0 0.053 13.7 0.0 2.2 2 1 0 2 2 2 0 U-box domain DUF4196 PF13846.6 OEU16327.1 - 0.44 10.8 6.4 0.96 9.7 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) WLM PF08325.10 OEU16329.1 - 7.9e-28 97.8 2.2 3.1e-27 95.9 2.2 1.8 1 1 0 1 1 1 1 WLM domain TnpV PF14198.6 OEU16329.1 - 0.061 13.3 0.5 0.16 11.9 0.2 1.8 1 1 0 1 1 1 0 Transposon-encoded protein TnpV Connexin PF00029.19 OEU16331.1 - 0.011 15.6 2.5 0.31 10.7 0.6 2.6 2 0 0 2 2 2 0 Connexin CLN3 PF02487.17 OEU16331.1 - 0.054 12.5 1.7 1 8.3 0.1 2.6 3 0 0 3 3 3 0 CLN3 protein TRAP_alpha PF03896.16 OEU16331.1 - 0.091 12.0 4.4 0.88 8.7 1.8 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit zf-MYND PF01753.18 OEU16333.1 - 3.4e-09 36.6 13.5 6.8e-09 35.7 13.5 1.5 1 0 0 1 1 1 1 MYND finger Ig_5 PF16681.5 OEU16335.1 - 0.054 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF1045 PF06299.12 OEU16336.1 - 0.016 15.1 0.1 0.052 13.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Acetyltransf_1 PF00583.25 OEU16338.1 - 4e-12 46.4 0.0 6.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU16338.1 - 2.7e-08 34.1 0.0 1e-07 32.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU16338.1 - 2e-07 30.9 0.0 4.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 OEU16338.1 - 1.5e-06 28.2 0.7 3.5e-06 27.0 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU16338.1 - 0.00052 20.1 0.1 0.039 14.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OEU16338.1 - 0.001 19.8 0.0 0.0027 18.4 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OEU16338.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU16338.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RIX1 PF08167.12 OEU16338.1 - 0.037 13.8 0.6 0.3 10.8 0.4 2.2 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT PF02985.22 OEU16339.1 - 1.3e-15 56.1 18.3 0.004 17.3 0.0 8.9 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 OEU16339.1 - 3e-14 53.1 23.4 3e-05 24.4 0.0 9.7 7 2 3 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.6 OEU16339.1 - 9.4e-11 42.0 0.4 0.033 14.6 0.0 5.4 4 2 0 4 4 4 2 HEAT repeats MMS19_C PF12460.8 OEU16339.1 - 3.8e-07 29.6 8.3 0.002 17.3 0.7 4.3 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 OEU16339.1 - 0.00062 20.3 0.0 8.4 7.1 0.0 4.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OEU16339.1 - 0.0036 17.4 0.0 15 5.6 0.0 4.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 OEU16339.1 - 0.013 14.9 2.5 0.15 11.3 0.6 2.8 3 0 0 3 3 3 0 V-ATPase subunit H TAF6_C PF07571.13 OEU16339.1 - 0.032 14.5 0.0 2.7 8.4 0.0 3.4 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Importin_rep_4 PF18808.1 OEU16339.1 - 0.22 11.8 3.6 28 5.1 0.0 2.8 2 0 0 2 2 2 0 Importin repeat DUF1981 PF09324.10 OEU16339.1 - 0.47 10.3 3.4 0.18 11.7 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) IFRD PF05004.13 OEU16339.1 - 0.75 8.8 3.8 3.2 6.8 0.0 3.2 3 2 0 3 3 3 0 Interferon-related developmental regulator (IFRD) CENP-B_dimeris PF09026.10 OEU16339.1 - 1.6 9.2 7.7 3.9 7.9 7.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Arm PF00514.23 OEU16339.1 - 2.2 8.4 9.6 51 4.1 0.0 5.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat UCR_14kD PF02271.16 OEU16341.1 - 3.4e-14 52.6 0.2 4e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DnaJ PF00226.31 OEU16342.1 - 2.3e-19 69.3 0.3 8.4e-19 67.5 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 OEU16342.1 - 2.9e-08 33.8 5.0 6e-08 32.8 5.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OEU16342.1 - 2.2e-07 31.0 6.7 2.2e-07 31.0 6.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OEU16342.1 - 1.1e-05 25.7 2.1 4e-05 23.9 2.1 2.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 OEU16342.1 - 0.014 15.6 4.9 0.014 15.6 4.9 3.0 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 OEU16342.1 - 0.016 16.0 1.7 0.042 14.7 1.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 OEU16342.1 - 0.019 15.1 4.8 0.061 13.4 4.8 1.9 1 0 0 1 1 1 0 DBF zinc finger Agenet PF05641.12 OEU16342.1 - 0.063 13.8 1.3 1.7 9.2 0.3 3.0 2 0 0 2 2 2 0 Agenet domain DHHC PF01529.20 OEU16346.1 - 1.6e-26 93.0 3.7 1.6e-26 93.0 3.7 2.5 2 2 0 2 2 2 1 DHHC palmitoyltransferase Comm PF15957.5 OEU16346.1 - 2.9 8.2 4.9 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 Commissureless MitMem_reg PF13012.6 OEU16347.1 - 5.4e-10 39.7 0.5 1.1e-09 38.7 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OEU16347.1 - 0.019 14.9 0.0 0.065 13.2 0.0 2.0 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FHA PF00498.26 OEU16348.1 - 6.4e-10 39.2 0.0 4.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 FHA domain RINGv PF12906.7 OEU16348.1 - 1.1e-09 38.3 8.1 2.2e-09 37.3 8.1 1.6 1 0 0 1 1 1 1 RING-variant domain Yop-YscD_cpl PF16697.5 OEU16348.1 - 8.2e-05 22.8 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 OEU16348.1 - 0.64 10.4 9.3 10 6.5 10.3 2.2 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 OEU16348.1 - 1.4 9.2 6.2 2.4 8.4 6.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 OEU16348.1 - 2.8 8.3 6.1 7.1 7.0 3.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain tRNA-synt_1d PF00750.19 OEU16349.1 - 8.3e-125 416.3 0.0 1.3e-124 415.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OEU16349.1 - 6.3e-29 100.6 0.1 1.3e-28 99.5 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OEU16349.1 - 8.5e-16 58.3 0.1 6.6e-15 55.5 0.0 2.5 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 OEU16349.1 - 6.9e-05 22.3 0.0 0.00018 21.0 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF647 PF04884.14 OEU16350.1 - 1e-68 231.6 1.0 1.2e-68 231.4 1.0 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TB2_DP1_HVA22 PF03134.19 OEU16351.1 - 4.8e-23 80.9 0.6 4.8e-23 80.9 0.6 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family YiaAB PF05360.14 OEU16351.1 - 0.024 14.8 1.8 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 yiaA/B two helix domain AAA_5 PF07728.14 OEU16352.1 - 7.4e-79 262.5 0.0 2.6e-27 95.5 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OEU16352.1 - 3.1e-07 30.7 0.0 0.48 10.5 0.0 3.6 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OEU16352.1 - 2.4e-06 28.1 1.0 0.077 13.4 0.0 5.1 4 2 1 6 6 6 1 AAA ATPase domain AAA PF00004.29 OEU16352.1 - 6.5e-05 23.4 0.0 0.47 10.9 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OEU16352.1 - 0.0005 19.5 0.2 16 4.8 0.0 4.4 4 1 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OEU16352.1 - 0.0017 18.2 0.0 2.3 8.1 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) VWA_2 PF13519.6 OEU16352.1 - 0.0048 17.5 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OEU16352.1 - 0.0092 16.2 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 1 1 von Willebrand factor type A domain AAA_7 PF12775.7 OEU16352.1 - 0.0099 15.4 0.0 2.2 7.7 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 OEU16352.1 - 0.033 13.6 0.1 5 6.5 0.0 3.1 4 0 0 4 4 4 0 Bacterial TniB protein Cast PF10174.9 OEU16352.1 - 0.049 11.9 2.1 0.073 11.3 2.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone AvrRpt-cleavage PF05627.11 OEU16352.1 - 0.057 12.8 0.6 0.14 11.5 0.6 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr RNA_helicase PF00910.22 OEU16352.1 - 0.16 12.4 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase CxxCxxCC PF03692.15 OEU16353.1 - 0.018 15.7 2.0 0.03 15.0 2.0 1.4 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain CxC6 PF18721.1 OEU16353.1 - 0.17 12.2 7.7 0.39 11.0 7.7 1.6 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases SUI1 PF01253.22 OEU16354.1 - 1.7e-24 86.1 1.4 2.1e-24 85.8 1.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Hydrophob_seed PF14547.6 OEU16354.1 - 0.055 13.7 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 Hydrophobic seed protein LRR_8 PF13855.6 OEU16355.1 - 1.3e-30 104.9 48.0 2e-07 30.7 3.1 8.3 4 3 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 OEU16355.1 - 1.7e-18 66.4 56.2 0.00075 19.8 1.7 10.7 3 2 11 14 14 14 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU16355.1 - 2.5e-07 30.3 42.4 21 6.2 0.0 15.0 17 0 0 17 17 17 5 Leucine Rich Repeat UCH PF00443.29 OEU16356.1 - 8.1e-71 238.5 0.5 9.2e-71 238.3 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU16356.1 - 4.3e-17 62.7 0.1 1.3e-15 57.9 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rtf2 PF04641.12 OEU16357.1 - 0.17 11.2 6.8 0.28 10.5 6.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Rgp1 PF08737.10 OEU16357.1 - 0.5 9.5 5.1 0.71 9.0 5.1 1.2 1 0 0 1 1 1 0 Rgp1 FG-GAP_2 PF14312.6 OEU16358.1 - 2e-19 69.5 33.4 7.9e-05 22.8 0.2 8.4 7 0 0 7 7 7 7 FG-GAP repeat FTCD_C PF04961.12 OEU16358.1 - 0.073 12.8 1.1 0.2 11.4 1.1 1.7 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Imm31 PF15591.6 OEU16358.1 - 0.073 12.9 0.3 0.25 11.2 0.3 1.9 1 0 0 1 1 1 0 Immunity protein 31 GATase_4 PF13230.6 OEU16359.1 - 7.8e-75 251.3 0.0 1.3e-74 250.5 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 OEU16359.1 - 0.00033 20.9 0.0 0.00056 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Methyltransf_11 PF08241.12 OEU16360.1 - 6.2e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16360.1 - 3.3e-17 63.0 0.0 5.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OEU16360.1 - 1.3e-16 60.8 0.0 1.7e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 OEU16360.1 - 5.1e-14 52.3 0.0 7.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16360.1 - 1.7e-11 44.2 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU16360.1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU16360.1 - 4.7e-09 36.9 0.0 7.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OEU16360.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.8 OEU16360.1 - 0.016 14.4 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 OEU16360.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 OEU16360.1 - 0.023 14.0 0.0 0.036 13.3 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 OEU16360.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Pkinase PF00069.25 OEU16361.1 - 7.6e-60 202.5 0.0 9.4e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16361.1 - 8.9e-27 94.0 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU16361.1 - 0.0034 16.7 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like NicO PF03824.16 OEU16362.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF3246 PF11596.8 OEU16362.1 - 1.1 8.6 5.1 2.7 7.4 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Otopetrin PF03189.13 OEU16362.1 - 1.3 7.8 5.1 2.9 6.6 0.3 2.5 2 1 0 2 2 2 0 Otopetrin hNIFK_binding PF12196.8 OEU16362.1 - 7.9 6.1 0.0 7.9 6.1 0.0 3.2 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Cupin_8 PF13621.6 OEU16363.1 - 2.4e-19 70.0 4.8 2.4e-19 70.0 4.8 3.5 3 1 0 3 3 3 1 Cupin-like domain JmjC PF02373.22 OEU16363.1 - 2.9e-12 47.0 1.1 8.9e-12 45.4 0.1 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 OEU16363.1 - 0.00076 19.0 1.3 0.0036 16.8 0.2 2.5 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 OEU16363.1 - 0.0016 18.1 0.3 0.011 15.4 0.1 2.1 2 0 0 2 2 2 1 Cupin domain T2SSC PF11356.8 OEU16363.1 - 0.041 13.8 1.0 0.098 12.6 1.0 1.6 1 0 0 1 1 1 0 Type II secretion system protein C F-box-like PF12937.7 OEU16363.1 - 0.052 13.5 0.7 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 F-box-like Cupin_1 PF00190.22 OEU16363.1 - 0.09 12.4 1.4 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Cupin TPK_catalytic PF04263.16 OEU16364.1 - 1.9e-30 105.3 0.1 3.5e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OEU16364.1 - 3.7e-15 55.4 0.0 7e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CSN8_PSD8_EIF3K PF10075.9 OEU16365.1 - 6.6e-21 74.8 0.0 9.4e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF3007 PF11460.8 OEU16366.1 - 3.9e-29 100.8 0.2 4.4e-29 100.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) UbiA PF01040.18 OEU16366.1 - 0.0018 17.6 1.9 0.002 17.5 1.9 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family TctB PF07331.11 OEU16366.1 - 0.0034 17.7 1.9 0.0041 17.4 1.9 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF5379 PF17350.2 OEU16366.1 - 0.0073 16.5 2.0 0.0099 16.1 2.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5379) SieB PF14163.6 OEU16366.1 - 0.013 15.0 0.8 0.022 14.2 0.8 1.5 1 1 0 1 1 1 0 Super-infection exclusion protein B Cation_ATPase_C PF00689.21 OEU16366.1 - 0.34 10.6 3.2 0.44 10.2 3.2 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Myb_DNA-binding PF00249.31 OEU16367.1 - 1.7e-54 181.8 15.6 8.2e-19 67.5 0.8 3.0 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU16367.1 - 3.8e-41 139.2 10.2 3.9e-18 65.4 1.4 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OEU16367.1 - 3e-07 30.4 0.3 0.52 10.3 0.0 3.2 1 1 1 3 3 3 3 SLIDE SANT_DAMP1_like PF16282.5 OEU16367.1 - 0.00039 20.6 1.0 0.61 10.3 0.1 3.1 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OEU16367.1 - 0.00044 20.3 8.5 1.1 9.4 2.3 3.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OEU16367.1 - 0.00063 19.6 1.8 0.26 11.2 0.0 3.0 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OEU16367.1 - 0.036 14.4 16.4 3.9 7.9 0.9 4.8 3 3 0 3 3 3 0 Myb/SANT-like DNA-binding domain Sigma70_r4_2 PF08281.12 OEU16367.1 - 0.045 13.4 0.0 0.7 9.6 0.0 2.6 3 0 0 3 3 3 0 Sigma-70, region 4 DUF3693 PF12472.8 OEU16367.1 - 0.093 12.4 0.5 7.3 6.3 0.3 2.5 2 0 0 2 2 2 0 Phage related protein EcpB_C PF18649.1 OEU16367.1 - 0.1 12.6 0.1 2.1 8.4 0.0 2.6 3 0 0 3 3 3 0 EcpB C-terminal domain PQQ_3 PF13570.6 OEU16368.1 - 0.0081 16.6 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 PQQ-like domain DGF-1_C PF11040.8 OEU16368.1 - 0.13 12.3 0.2 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PMP22_Claudin PF00822.20 OEU16369.1 - 4.5 7.1 9.7 34 4.3 10.5 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Ank_5 PF13857.6 OEU16370.1 - 1.5e-07 31.6 0.0 0.0012 19.2 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) PhyH PF05721.13 OEU16371.1 - 1e-11 45.5 0.0 1.4e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GET2 PF08690.10 OEU16373.1 - 1.8 8.2 11.1 6.5 6.3 11.1 1.9 1 0 0 1 1 1 0 GET complex subunit GET2 DnaJ-X PF14308.6 OEU16373.1 - 3.5 7.0 9.2 3 7.2 6.9 2.1 2 0 0 2 2 2 0 X-domain of DnaJ-containing DUF2755 PF10954.8 OEU16375.1 - 0.089 12.7 3.7 0.52 10.3 3.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) NAD_binding_5 PF07994.12 OEU16376.1 - 6.4e-140 466.1 0.0 7.6e-140 465.9 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OEU16376.1 - 1.1e-46 157.6 0.2 2.3e-46 156.5 0.2 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Peptidase_C97 PF05903.14 OEU16377.1 - 1e-29 103.3 0.1 1.1e-29 103.2 0.1 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain EMP24_GP25L PF01105.24 OEU16378.1 - 3.7e-22 79.1 0.1 4.2e-22 79.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sec34 PF04136.15 OEU16378.1 - 0.04 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Sec34-like family RNase_PH PF01138.21 OEU16379.1 - 1.3e-34 119.5 0.0 1.5e-21 77.3 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OEU16379.1 - 4.5e-16 58.6 2.7 2.8e-10 40.1 0.1 3.2 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 OEU16379.1 - 2.2e-07 30.6 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 KH domain PNPase PF03726.14 OEU16379.1 - 0.00012 22.5 0.1 0.00024 21.5 0.1 1.5 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 OEU16379.1 - 0.00071 19.9 0.3 0.0032 17.8 0.3 2.1 1 1 0 1 1 1 1 S1 RNA binding domain KH_5 PF13184.6 OEU16379.1 - 0.012 15.7 0.7 0.037 14.1 0.1 2.1 2 0 0 2 2 2 0 NusA-like KH domain KH_4 PF13083.6 OEU16379.1 - 0.18 11.7 0.4 2.2 8.2 0.0 2.8 3 0 0 3 3 3 0 KH domain WD40 PF00400.32 OEU16380.1 - 1.7e-35 120.4 13.1 1.9e-09 37.9 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU16380.1 - 1.5e-12 47.6 0.0 0.00094 19.4 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OEU16380.1 - 2.5e-06 26.3 0.1 5.1e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OEU16380.1 - 8.8e-06 24.9 0.0 0.18 10.7 0.0 3.9 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OEU16380.1 - 9.2e-05 21.3 0.3 0.2 10.2 0.2 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OEU16380.1 - 0.0025 16.6 0.3 1.1 7.9 0.1 3.3 2 1 1 3 3 3 2 Nup133 N terminal like SUKH-4 PF14435.6 OEU16380.1 - 0.11 12.5 0.0 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 SUKH-4 immunity protein SR-25 PF10500.9 OEU16381.1 - 6 6.4 39.8 7.8 6.0 39.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.6 OEU16382.1 - 0.21 12.0 6.2 8.1 6.9 3.2 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.17 OEU16382.1 - 6.8 6.7 28.5 8.8 6.3 7.7 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein Fasciclin PF02469.22 OEU16383.1 - 1.3e-08 35.1 0.0 2.9e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain GST_N PF02798.20 OEU16384.1 - 4.7e-05 23.6 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU16384.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU16384.1 - 0.036 14.5 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TLD PF07534.16 OEU16386.1 - 4e-08 33.6 0.0 4.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 TLD LON_substr_bdg PF02190.16 OEU16387.1 - 3e-07 30.5 0.1 5.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Toprim_3 PF13362.6 OEU16387.1 - 0.56 10.6 3.6 0.45 10.9 0.3 2.6 2 1 0 2 2 2 0 Toprim domain Cwf_Cwc_15 PF04889.12 OEU16387.1 - 1.6 8.4 5.8 1.7 8.3 1.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WRNPLPNID PF15017.6 OEU16387.1 - 2.6 9.0 6.9 32 5.5 0.0 3.2 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box HA PF03457.14 OEU16388.1 - 8.2e-13 48.5 0.1 9.6e-05 22.6 0.1 3.2 3 0 0 3 3 3 2 Helicase associated domain DNA_pol_A_exo1 PF01612.20 OEU16389.1 - 1.9e-16 60.3 0.0 3.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease ThiC_Rad_SAM PF01964.18 OEU16390.1 - 1.9e-191 636.4 0.0 2.3e-191 636.1 0.0 1.1 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 OEU16390.1 - 5.8e-10 38.9 0.0 1.7e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 ThiC-associated domain Nuc_sug_transp PF04142.15 OEU16391.1 - 1.2e-26 93.7 7.3 1.5e-26 93.4 7.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OEU16391.1 - 5.3e-05 23.4 14.0 0.012 15.8 4.0 2.6 2 1 0 2 2 2 2 EamA-like transporter family DEAD PF00270.29 OEU16392.1 - 1.2e-44 152.2 0.0 2.6e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU16392.1 - 5.9e-26 91.0 0.1 4.7e-25 88.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OEU16392.1 - 2.4e-16 59.7 0.2 4.7e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 OEU16392.1 - 0.00016 21.0 0.0 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SPT6_acidic PF14632.6 OEU16392.1 - 0.096 13.3 15.1 0.32 11.6 15.1 2.0 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Cyt_c_ox_IV PF12270.8 OEU16392.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Tim54 PF11711.8 OEU16392.1 - 0.21 10.3 7.9 0.37 9.5 7.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3464 PF11947.8 OEU16392.1 - 1.5 8.6 5.4 3.3 7.4 5.4 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SOBP PF15279.6 OEU16392.1 - 1.6 9.2 6.7 2.6 8.6 6.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 OEU16392.1 - 1.6 7.8 4.3 0.96 8.6 2.3 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter CKAP2_C PF15297.6 OEU16392.1 - 5.4 6.0 13.8 8.5 5.4 13.8 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CENP-N PF05238.13 OEU16392.1 - 7.4 5.8 9.7 7.5 5.7 6.9 2.0 2 0 0 2 2 2 0 Kinetochore protein CHL4 like zf-HIT PF04438.16 OEU16393.1 - 0.00021 21.1 12.1 0.00041 20.1 12.1 1.5 1 0 0 1 1 1 1 HIT zinc finger Isochorismatase PF00857.20 OEU16394.1 - 1.4e-26 93.8 0.7 1.7e-26 93.5 0.7 1.1 1 0 0 1 1 1 1 Isochorismatase family His_Phos_1 PF00300.22 OEU16396.1 - 7.2e-33 113.9 0.0 9e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Neuromodulin PF06614.11 OEU16398.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.5 2 0 0 2 2 2 0 Neuromodulin TBCA PF02970.16 OEU16399.1 - 1.7e-26 92.4 3.3 2.4e-26 91.9 3.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Biotin_carb_C PF02785.19 OEU16399.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain TMEM51 PF15345.6 OEU16399.1 - 0.016 15.1 1.7 0.019 14.8 1.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3067 PF11267.8 OEU16401.1 - 3.2e-25 88.6 0.1 5.9e-25 87.7 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3067) WBS_methylT PF12589.8 OEU16402.1 - 4.4e-15 56.2 13.0 4.4e-15 56.2 13.0 2.1 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 OEU16402.1 - 1.3e-10 41.8 0.6 2e-07 31.6 0.2 2.7 2 1 1 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16402.1 - 3.8e-10 40.3 0.0 7.5e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16402.1 - 3.1e-06 27.9 0.0 1.5e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16402.1 - 7.1e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU16402.1 - 0.00013 21.8 0.0 0.0023 17.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OEU16402.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.18 OEU16402.1 - 0.026 14.3 1.9 0.16 11.6 0.0 2.3 2 1 0 2 2 2 0 DNA methylase Methyltransf_32 PF13679.6 OEU16402.1 - 0.026 14.5 1.9 0.038 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OEU16402.1 - 0.032 13.6 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OEU16402.1 - 0.05 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 OEU16402.1 - 0.079 12.2 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 OEU16402.1 - 0.087 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase p450 PF00067.22 OEU16403.1 - 5e-69 233.2 0.1 6.5e-69 232.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 OEU16403.1 - 0.094 12.4 0.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Lectin_like PF18560.1 OEU16405.1 - 0.089 12.9 0.2 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Lectin like domain SWI-SNF_Ssr4 PF08549.10 OEU16406.1 - 4.4 5.8 37.0 0.022 13.4 11.2 2.0 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) Methyltransf_31 PF13847.6 OEU16407.1 - 0.0017 18.1 0.4 0.0051 16.6 0.4 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16407.1 - 0.0032 18.1 0.0 0.0097 16.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OEU16407.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 OEU16407.1 - 0.029 15.0 0.0 0.13 12.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 OEU16407.1 - 0.035 15.1 0.0 0.57 11.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain DUF3846 PF12957.7 OEU16407.1 - 0.46 10.8 4.3 3.6 8.0 4.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3846) Elong-fact-P_C PF09285.11 OEU16408.1 - 1e-21 76.4 0.3 2.3e-21 75.3 0.3 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 OEU16408.1 - 5.2e-20 71.2 0.5 1.5e-19 69.8 0.6 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 OEU16408.1 - 8.7e-14 51.3 0.2 2e-13 50.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain ABC_tran PF00005.27 OEU16409.1 - 3.7e-51 173.2 0.9 8.1e-25 87.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OEU16409.1 - 7.8e-17 61.1 17.3 3.8e-14 52.5 1.0 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OEU16409.1 - 1.4e-11 44.8 10.3 0.00046 20.1 0.1 4.5 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU16409.1 - 4e-08 33.0 10.7 0.02 14.3 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU16409.1 - 2.5e-07 31.0 3.2 0.00065 20.0 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU16409.1 - 7.7e-07 29.6 0.0 0.038 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU16409.1 - 8e-07 28.7 0.2 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OEU16409.1 - 1.1e-05 25.5 0.9 0.032 14.3 0.0 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 OEU16409.1 - 5.6e-05 23.3 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OEU16409.1 - 0.00011 22.7 1.2 0.37 11.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OEU16409.1 - 0.00018 21.5 2.3 0.2 11.5 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 OEU16409.1 - 0.00028 21.2 0.8 0.31 11.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OEU16409.1 - 0.00029 20.6 3.1 0.95 9.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain cobW PF02492.19 OEU16409.1 - 0.00073 19.2 0.3 0.26 10.9 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 OEU16409.1 - 0.00077 19.5 0.3 0.52 10.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 OEU16409.1 - 0.0011 18.7 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OEU16409.1 - 0.0013 18.6 0.0 0.43 10.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 OEU16409.1 - 0.0015 18.0 0.2 0.57 9.7 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA PF00004.29 OEU16409.1 - 0.0016 18.9 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OEU16409.1 - 0.0024 17.2 0.0 0.66 9.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 OEU16409.1 - 0.0043 17.6 24.5 0.041 14.4 0.5 4.4 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.6 OEU16409.1 - 0.0065 16.1 0.6 0.28 10.7 0.0 3.1 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.23 OEU16409.1 - 0.0084 16.2 4.8 0.068 13.2 0.0 3.0 3 1 0 3 3 2 1 Dynamin family SRP54 PF00448.22 OEU16409.1 - 0.0085 15.7 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RuvB_N PF05496.12 OEU16409.1 - 0.011 15.5 0.0 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OEU16409.1 - 0.014 15.4 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OEU16409.1 - 0.019 15.4 0.0 5.1 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 OEU16409.1 - 0.023 13.8 0.3 0.74 8.8 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein ATPase_2 PF01637.18 OEU16409.1 - 0.026 14.4 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 OEU16409.1 - 0.039 14.2 4.0 1.8 8.8 0.0 3.6 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 OEU16409.1 - 0.058 13.1 0.1 0.78 9.5 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein MeaB PF03308.16 OEU16409.1 - 0.07 12.1 0.0 5.3 5.9 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 OEU16409.1 - 0.1 12.3 0.0 0.1 12.3 0.0 4.2 1 1 2 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 OEU16409.1 - 0.12 11.0 7.7 0.92 8.1 2.3 3.0 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OEU16409.1 - 0.13 11.6 3.1 0.72 9.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family LXG PF04740.12 OEU16409.1 - 0.24 11.1 8.2 6 6.5 4.6 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF87 PF01935.17 OEU16409.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.6 3 1 1 4 4 4 0 Helicase HerA, central domain AAA_17 PF13207.6 OEU16409.1 - 4.6 7.7 10.8 19 5.7 3.3 3.6 3 1 1 4 4 3 0 AAA domain His_Phos_1 PF00300.22 OEU16410.1 - 9.7e-08 31.9 0.0 0.012 15.3 0.0 3.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ecm29 PF13001.7 OEU16410.1 - 0.076 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser RasGEF PF00617.19 OEU16410.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.4 1 1 0 1 1 1 0 RasGEF domain Pkinase PF00069.25 OEU16411.1 - 9.3e-31 107.1 0.0 5.1e-30 104.7 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16411.1 - 5.8e-30 104.4 0.0 1.1e-29 103.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU16411.1 - 0.0028 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Tropomodulin PF03250.14 OEU16411.1 - 0.043 13.9 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 Tropomodulin DUF3493 PF11998.8 OEU16412.1 - 5.1e-19 68.2 1.7 6.3e-19 67.9 0.1 1.9 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 PPR_2 PF13041.6 OEU16413.1 - 3e-18 65.7 1.0 3.4e-08 33.6 0.0 6.5 5 1 2 7 7 7 4 PPR repeat family PPR_3 PF13812.6 OEU16413.1 - 4.5e-16 58.7 0.1 3.6e-07 30.2 0.0 4.8 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU16413.1 - 2.6e-07 30.2 7.6 0.93 9.2 0.0 6.2 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 OEU16413.1 - 6.9e-07 29.1 6.4 15 6.1 0.0 7.7 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 OEU16413.1 - 0.00026 20.4 0.1 1.2 8.4 0.0 3.8 3 1 0 4 4 4 1 Pentacotripeptide-repeat region of PRORP CRM1_C PF08767.11 OEU16414.1 - 3.7e-121 404.2 3.1 1.7e-120 402.1 1.7 2.4 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OEU16414.1 - 3.2e-38 131.1 2.7 3.2e-38 131.1 2.7 3.2 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OEU16414.1 - 3.7e-33 113.0 0.9 1.2e-32 111.3 0.9 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OEU16414.1 - 5.6e-27 93.6 0.4 5.6e-27 93.6 0.4 2.4 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OEU16414.1 - 2.3e-17 62.2 0.2 5.2e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OEU16414.1 - 5.2e-13 48.7 0.1 2.2e-12 46.7 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 OEU16414.1 - 0.0029 16.2 0.5 0.52 8.8 0.0 2.8 3 0 0 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 OEU16414.1 - 0.0049 16.8 1.6 0.54 10.2 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) BID PF06393.11 OEU16414.1 - 0.02 14.4 0.3 0.29 10.6 0.0 2.9 3 0 0 3 3 3 0 BH3 interacting domain (BID) HEAT PF02985.22 OEU16414.1 - 0.17 12.2 0.0 1.4e+02 3.1 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat 2OG-FeII_Oxy_3 PF13640.6 OEU16415.1 - 2.6e-19 69.9 0.0 4.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 OEU16415.1 - 0.0084 15.3 0.0 0.013 14.7 0.0 1.4 1 1 0 1 1 1 1 Poxvirus C4/C10 protein Mito_carr PF00153.27 OEU16416.1 - 2.5e-39 133.1 8.7 2.9e-14 52.8 0.2 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein Proton_antipo_M PF00361.20 OEU16416.1 - 0.0064 15.7 11.1 0.14 11.3 0.7 2.1 2 0 0 2 2 2 2 Proton-conducting membrane transporter E3_UFM1_ligase PF09743.9 OEU16416.1 - 0.0067 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 DUF1891 PF09004.10 OEU16416.1 - 0.042 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Hid1 PF12722.7 OEU16417.1 - 0.00062 18.1 6.3 0.00062 18.1 6.3 2.1 3 0 0 3 3 3 1 High-temperature-induced dauer-formation protein CNDH2_C PF16858.5 OEU16417.1 - 0.0039 17.1 8.5 0.0039 17.1 8.5 2.6 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term MENTAL PF10457.9 OEU16417.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.2 3 0 0 3 3 3 0 Cholesterol-capturing domain Androgen_recep PF02166.16 OEU16417.1 - 0.49 9.2 7.1 0.08 11.8 2.9 1.8 2 0 0 2 2 2 0 Androgen receptor SDA1 PF05285.12 OEU16417.1 - 4.5 6.6 21.6 0.29 10.5 12.6 2.3 2 0 0 2 2 2 0 SDA1 zf-MYND PF01753.18 OEU16418.1 - 2.8e-05 24.1 15.7 2.8e-05 24.1 15.7 1.9 2 0 0 2 2 2 1 MYND finger IBR PF01485.21 OEU16419.1 - 1.6e-15 57.0 30.7 4.8e-09 36.3 7.8 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OEU16419.1 - 7.2e-06 25.8 8.8 7.2e-06 25.8 8.8 5.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU16419.1 - 2.1e-05 24.4 5.7 2.1e-05 24.4 5.7 4.6 4 2 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU16419.1 - 0.00013 22.2 7.9 0.00013 22.2 7.9 5.2 3 2 2 5 5 5 2 Ring finger domain zf-C3HC4 PF00097.25 OEU16419.1 - 0.00024 20.9 6.0 0.00024 20.9 6.0 5.2 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU16419.1 - 0.0017 18.0 2.9 0.0017 18.0 2.9 4.6 5 0 0 5 5 5 1 RING-like zinc finger Holin_BhlA PF10960.8 OEU16419.1 - 0.092 12.7 0.5 0.21 11.6 0.5 1.5 1 0 0 1 1 1 0 BhlA holin family Phage_TAC_4 PF08748.11 OEU16420.1 - 0.012 15.9 0.1 0.027 14.8 0.1 1.8 1 1 0 1 1 1 0 Phage tail assembly chaperone rve PF00665.26 OEU16421.1 - 3.2e-11 43.5 0.0 4.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Herpes_pp85 PF04637.12 OEU16422.1 - 5.8 5.2 6.5 9.1 4.6 6.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2570 PF10828.8 OEU16423.1 - 0.6 10.0 5.0 1.6 8.5 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PBP1_TM PF14812.6 OEU16425.1 - 0.0002 21.7 1.1 0.0002 21.7 1.1 3.5 3 1 1 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OEU16425.1 - 7.2 7.1 12.9 17 5.8 5.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TSKS PF15358.6 OEU16426.1 - 0.03 12.7 0.1 0.037 12.4 0.1 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Glyco_hydro_30 PF02055.16 OEU16428.1 - 1e-58 199.0 5.1 8.3e-39 133.5 1.1 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OEU16428.1 - 4.3e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Peptidase_M48 PF01435.18 OEU16428.1 - 0.0084 15.9 0.0 0.038 13.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M48 PCRF PF03462.18 OEU16429.1 - 9.3e-67 224.6 0.4 9.3e-67 224.6 0.4 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OEU16429.1 - 5.1e-37 126.3 0.9 1.2e-36 125.2 0.9 1.6 1 0 0 1 1 1 1 RF-1 domain FlxA PF14282.6 OEU16430.1 - 0.0079 16.2 5.8 0.0079 16.2 5.8 4.5 3 2 2 5 5 5 1 FlxA-like protein TMF_TATA_bd PF12325.8 OEU16430.1 - 0.015 15.5 1.9 0.015 15.5 1.9 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 OEU16430.1 - 0.044 13.9 0.4 0.044 13.9 0.4 4.0 4 1 1 5 5 5 0 bZIP transcription factor ZapB PF06005.12 OEU16430.1 - 0.058 13.8 1.0 0.058 13.8 1.0 4.1 3 2 0 3 3 3 0 Cell division protein ZapB IMUP PF15761.5 OEU16430.1 - 0.27 12.0 12.8 0.4 11.4 7.6 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Fib_alpha PF08702.10 OEU16430.1 - 4.4 7.5 26.5 0.87 9.8 2.3 3.8 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family EMP70 PF02990.16 OEU16431.1 - 1.1e-172 575.4 1.3 1.4e-172 575.0 1.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 LRR_8 PF13855.6 OEU16432.1 - 2.1e-34 117.0 73.2 3.6e-08 33.0 3.3 10.3 4 3 8 13 13 13 13 Leucine rich repeat LRR_4 PF12799.7 OEU16432.1 - 6.2e-27 93.2 80.7 2.6e-06 27.7 2.4 12.1 4 4 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU16432.1 - 7e-15 53.3 58.9 1.7 9.5 0.0 17.2 15 2 1 16 16 16 6 Leucine Rich Repeat DUF5612 PF18462.1 OEU16432.1 - 0.031 14.1 0.7 24 4.7 0.1 4.4 4 2 1 6 6 6 0 Domain of unknown function (DUF5612) LRR_6 PF13516.6 OEU16432.1 - 0.044 13.9 56.8 0.54 10.5 0.1 13.6 16 0 0 16 16 16 0 Leucine Rich repeat LRR_9 PF14580.6 OEU16432.1 - 0.28 10.7 21.9 0.45 10.0 0.2 4.6 1 1 4 5 5 5 0 Leucine-rich repeat FAD_binding_3 PF01494.19 OEU16433.1 - 2.1e-11 43.7 2.1 2.2e-09 37.0 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 OEU16433.1 - 3.2e-05 24.0 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU16433.1 - 0.0015 17.8 0.3 0.012 14.8 0.1 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU16433.1 - 0.0016 18.1 0.1 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OEU16433.1 - 0.0032 16.7 0.1 0.0077 15.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OEU16433.1 - 0.0039 17.4 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OEU16433.1 - 0.054 12.7 0.4 0.054 12.7 0.4 2.6 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU16433.1 - 0.1 11.3 0.4 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 OEU16433.1 - 0.14 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Peptidase_S49 PF01343.18 OEU16434.1 - 4.5e-39 133.9 0.0 6.6e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 OEU16434.1 - 6.6e-15 55.5 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 OEU16434.1 - 0.0016 17.5 0.1 0.0023 17.0 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 OEU16434.1 - 0.0065 16.4 1.4 2.2 8.2 0.1 2.3 2 0 0 2 2 2 2 Clp protease ECH_1 PF00378.20 OEU16434.1 - 0.26 10.6 2.4 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Methyltrans_SAM PF10672.9 OEU16435.1 - 5.9e-17 61.8 0.0 1.2e-16 60.8 0.0 1.4 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 OEU16435.1 - 1.2e-12 47.9 0.2 2e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OEU16435.1 - 5.3e-11 42.5 0.0 8.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 OEU16435.1 - 3.1e-10 39.9 0.1 5.4e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OEU16435.1 - 2.6e-08 34.4 0.0 5.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU16435.1 - 3e-07 30.1 0.1 4.8e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PUA_3 PF17785.1 OEU16435.1 - 4.1e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 PUA-like domain FtsJ PF01728.19 OEU16435.1 - 7.4e-06 26.2 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OEU16435.1 - 4.5e-05 23.2 0.3 0.00053 19.7 0.3 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TRM PF02005.16 OEU16435.1 - 0.0011 18.2 1.5 0.0028 16.9 1.5 1.6 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_11 PF08241.12 OEU16435.1 - 0.002 18.8 0.0 0.0047 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OEU16435.1 - 0.0028 17.4 0.0 0.008 15.9 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_23 PF13489.6 OEU16435.1 - 0.0035 17.2 0.1 0.007 16.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OEU16435.1 - 0.0043 17.0 0.1 0.0082 16.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 OEU16435.1 - 0.0044 16.3 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 OEU16435.1 - 0.0046 16.7 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 OEU16435.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.16 OEU16435.1 - 0.081 12.0 0.4 0.15 11.2 0.4 1.4 1 0 0 1 1 1 0 mRNA capping enzyme DNA_methylase PF00145.17 OEU16435.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_9 PF08003.11 OEU16435.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) N6-adenineMlase PF10237.9 OEU16435.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase AAA_16 PF13191.6 OEU16437.1 - 7.5e-21 75.2 0.0 1.6e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OEU16437.1 - 0.0077 16.1 0.1 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase TPR_12 PF13424.6 OEU16437.1 - 0.032 14.5 1.9 2.7 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_helicase PF00910.22 OEU16437.1 - 0.052 13.9 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 OEU16437.1 - 0.11 12.3 1.1 0.22 11.3 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TPR_2 PF07719.17 OEU16437.1 - 7.3 7.0 7.4 19 5.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Proteasome PF00227.26 OEU16438.1 - 3.9e-26 91.7 0.0 9.9e-15 54.5 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit zf-C2HC5 PF06221.13 OEU16439.1 - 1.2e-07 31.6 5.6 2.4e-07 30.6 5.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type AF-4 PF05110.13 OEU16439.1 - 0.00053 18.2 15.1 0.00079 17.7 15.1 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Ndc1_Nup PF09531.10 OEU16439.1 - 0.041 12.6 6.1 0.043 12.5 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Menin PF05053.13 OEU16439.1 - 0.9 7.8 10.3 1.4 7.2 10.3 1.2 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 OEU16439.1 - 1.5 5.9 12.4 2 5.5 12.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer COX5B PF01215.19 OEU16440.1 - 1.7e-07 31.0 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb PH PF00169.29 OEU16441.1 - 1.6e-10 41.5 0.2 0.0006 20.3 0.1 3.0 1 1 1 2 2 2 2 PH domain PH_11 PF15413.6 OEU16441.1 - 5.5e-05 23.5 0.6 0.00087 19.7 0.6 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain SbcCD_C PF13558.6 OEU16441.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit zf-CCHC PF00098.23 OEU16442.1 - 0.004 17.2 5.2 0.0084 16.1 5.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OEU16442.1 - 0.18 11.6 1.7 0.33 10.7 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle PP2C PF00481.21 OEU16444.1 - 3.5e-47 161.2 0.5 4.4e-46 157.6 0.5 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU16444.1 - 0.00017 21.3 0.3 0.025 14.2 0.0 2.7 1 1 1 2 2 2 2 Protein phosphatase 2C DUF1266 PF06889.11 OEU16444.1 - 0.029 14.4 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) SpoIIE PF07228.12 OEU16444.1 - 0.03 14.2 0.0 0.095 12.6 0.0 1.8 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) ABC_tran PF00005.27 OEU16445.1 - 3.7e-26 92.3 0.0 2e-12 47.8 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OEU16445.1 - 2.9e-09 37.2 2.4 0.0058 16.5 0.2 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OEU16445.1 - 1.3e-07 31.5 3.7 2.5e-07 30.6 3.7 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU16445.1 - 1.3e-06 28.0 0.2 0.16 11.4 0.0 3.1 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 OEU16445.1 - 0.0014 17.8 0.1 0.0035 16.6 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.6 OEU16445.1 - 0.0026 17.4 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU16445.1 - 0.0056 17.2 0.0 0.0056 17.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OEU16445.1 - 0.01 15.7 0.3 0.042 13.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 OEU16445.1 - 0.017 14.9 3.4 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 OEU16445.1 - 0.022 14.7 0.2 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 OEU16445.1 - 0.043 14.1 0.5 0.21 11.8 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU16445.1 - 0.078 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 OEU16445.1 - 0.16 11.9 1.3 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 OEU16445.1 - 5.9 6.9 6.6 9.3 6.3 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain DUF4718 PF15842.5 OEU16446.1 - 0.36 10.6 3.4 0.2 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Abhydrolase_6 PF12697.7 OEU16447.1 - 0.0012 19.4 0.1 0.0026 18.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.25 OEU16448.1 - 3e-08 33.3 0.0 3.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU16448.1 - 2.3e-05 23.3 0.0 3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase GMP_synt_C PF00958.22 OEU16450.1 - 1.1e-39 134.3 0.0 2.7e-39 133.1 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OEU16450.1 - 8.2e-38 130.1 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OEU16450.1 - 4.4e-10 39.7 0.0 1e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 OEU16450.1 - 1.2e-06 27.8 0.0 3.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 OEU16450.1 - 0.0032 17.1 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 OEU16450.1 - 0.012 14.4 0.1 0.025 13.4 0.1 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.19 OEU16450.1 - 0.054 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase QueC PF06508.13 OEU16450.1 - 0.063 12.8 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Pyr_redox_2 PF07992.14 OEU16452.1 - 0.00015 21.1 0.2 0.0098 15.1 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU16452.1 - 0.00098 19.1 0.0 1.3 9.0 0.0 2.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OEU16452.1 - 0.003 16.9 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OEU16452.1 - 0.0031 17.7 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain YscW PF09619.10 OEU16452.1 - 0.029 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) Pyr_redox PF00070.27 OEU16452.1 - 0.077 13.6 1.2 0.28 11.8 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU16452.1 - 0.12 11.9 0.0 0.88 9.1 0.0 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase PsbM PF05151.12 OEU16452.1 - 3 7.7 6.3 5.8 6.8 6.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Lyase_1 PF00206.20 OEU16453.1 - 6.2e-108 360.9 0.0 7.6e-108 360.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OEU16453.1 - 2.2e-24 85.6 0.2 8.8e-24 83.7 0.0 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus PTR2 PF00854.21 OEU16454.1 - 7.5e-88 295.0 2.2 4.1e-87 292.6 1.7 2.0 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 OEU16454.1 - 2.9e-12 46.2 9.3 7.2e-07 28.4 0.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily SAYSvFN PF10260.9 OEU16454.1 - 0.015 15.2 0.9 0.46 10.4 0.1 3.2 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) 5TM-5TMR_LYT PF07694.12 OEU16454.1 - 0.017 14.6 0.1 0.017 14.6 0.1 2.9 3 0 0 3 3 3 0 5TMR of 5TMR-LYT KCT2 PF17818.1 OEU16454.1 - 0.079 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte-associated gene product DUF2645 PF10840.8 OEU16454.1 - 0.46 11.1 4.2 0.89 10.2 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2645) Saf_2TM PF18303.1 OEU16454.1 - 0.55 9.8 3.3 7.5 6.1 0.2 3.2 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain CK_II_beta PF01214.18 OEU16455.1 - 2.5e-65 219.7 0.0 5.9e-65 218.5 0.0 1.6 2 0 0 2 2 2 1 Casein kinase II regulatory subunit DUF1077 PF06417.12 OEU16456.1 - 2.8e-29 101.5 3.2 4e-29 101.0 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Aminotran_3 PF00202.21 OEU16457.1 - 1.1e-113 380.0 0.0 1.3e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF334 PF03904.13 OEU16458.1 - 0.81 9.2 6.4 1 8.8 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Shugoshin_N PF07558.11 OEU16462.1 - 0.04 13.8 3.4 42 4.1 0.1 3.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region UVR PF02151.19 OEU16463.1 - 0.00069 19.3 2.3 0.00069 19.3 2.3 4.9 5 0 0 5 5 5 3 UvrB/uvrC motif Peptidase_M23 PF01551.22 OEU16466.1 - 2.3e-15 56.6 0.0 1.8e-14 53.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M23 Pyrid_oxidase_2 PF13883.6 OEU16467.1 - 2.2e-17 63.6 0.0 4.6e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 OEU16467.1 - 3e-08 33.7 0.0 6.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 OEU16467.1 - 7.4e-08 32.9 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Patatin PF01734.22 OEU16469.1 - 1.6e-27 97.0 0.1 3.4e-27 96.0 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Arm PF00514.23 OEU16469.1 - 0.028 14.4 0.9 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HisKA_4TM PF16926.5 OEU16469.1 - 0.039 13.5 0.3 0.12 12.0 0.2 1.8 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase Ank_2 PF12796.7 OEU16470.1 - 3.4e-11 43.6 0.0 2.1e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU16470.1 - 2.9e-10 40.5 0.6 2.4e-07 31.1 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU16470.1 - 6.3e-09 35.4 0.0 0.00037 20.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OEU16470.1 - 1.4e-07 31.6 0.0 0.0007 19.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OEU16470.1 - 0.0004 20.6 0.0 0.25 11.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PP2C PF00481.21 OEU16471.1 - 2.6e-26 92.8 0.0 9.2e-26 91.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 OEU16472.1 - 5.4e-19 68.8 0.0 3.1e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Bgal_small_N PF02929.17 OEU16472.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Beta galactosidase small chain DnaJ PF00226.31 OEU16473.1 - 1.1e-11 44.7 0.1 3.2e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 OEU16473.1 - 0.0015 18.2 0.0 0.0052 16.6 0.0 1.9 1 0 0 1 1 1 1 GYF domain 2 Brr6_like_C_C PF10104.9 OEU16473.1 - 0.042 13.6 0.7 0.91 9.3 0.0 2.6 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain UQ_con PF00179.26 OEU16474.1 - 1.9e-47 160.4 0.0 2.1e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CoA_binding PF02629.19 OEU16475.1 - 1.4e-31 109.0 3.1 1.4e-31 109.0 0.3 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OEU16475.1 - 6.1e-24 84.6 0.1 1.1e-23 83.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OEU16475.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OEU16475.1 - 8.6e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain AMP-binding PF00501.28 OEU16476.1 - 2.7e-07 29.5 0.0 3.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NIR_SIR PF01077.22 OEU16477.1 - 1e-48 164.8 0.2 1.9e-35 121.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OEU16477.1 - 4.5e-36 122.5 0.0 4.5e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain HECT PF00632.25 OEU16478.1 - 1.3e-92 310.6 0.0 1.6e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fib_alpha PF08702.10 OEU16480.1 - 0.031 14.5 5.9 0.05 13.8 5.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 OEU16480.1 - 0.04 14.4 5.4 0.058 13.9 5.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 OEU16480.1 - 0.12 12.5 4.3 0.17 12.0 4.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1043 PF06295.12 OEU16480.1 - 0.16 12.0 5.0 0.24 11.4 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) XhlA PF10779.9 OEU16480.1 - 0.65 10.2 7.1 0.21 11.8 1.9 2.3 1 1 1 2 2 2 0 Haemolysin XhlA COX16 PF14138.6 OEU16480.1 - 0.85 10.2 0.1 0.85 10.2 0.1 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Prp18 PF02840.15 OEU16481.1 - 2.3e-56 189.8 0.1 2.6e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Prp18 domain Band_7 PF01145.25 OEU16482.1 - 3.7e-26 92.2 0.6 5.6e-26 91.6 0.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF533 PF04391.12 OEU16482.1 - 6.9 6.2 8.2 17 4.9 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DnaJ PF00226.31 OEU16483.1 - 3.6e-18 65.4 1.0 8e-18 64.3 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 OEU16483.1 - 0.0041 16.8 7.7 0.29 10.9 7.7 2.5 1 1 0 1 1 1 1 CSL zinc finger Methyltrans_SAM PF10672.9 OEU16484.1 - 1.5e-19 70.2 0.0 5.6e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 OEU16484.1 - 2e-06 27.5 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 OEU16484.1 - 5.2e-06 26.1 0.0 8.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Spermine_synth PF01564.17 OEU16484.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltr_RsmB-F PF01189.17 OEU16484.1 - 0.021 14.5 0.0 0.074 12.7 0.0 1.8 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 OEU16484.1 - 0.028 15.1 0.0 0.061 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 OEU16484.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MBOAT PF03062.19 OEU16485.1 - 1.1e-25 90.8 7.9 2e-25 89.9 7.8 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Cyclin_N PF00134.23 OEU16486.1 - 7e-50 168.0 2.7 1e-46 157.8 0.6 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU16486.1 - 6.4e-27 94.0 0.2 1e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.25 OEU16487.1 - 1.1e-35 123.3 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16487.1 - 6.1e-22 78.1 0.0 1.8e-21 76.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU16487.1 - 4.9e-05 22.8 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU16487.1 - 0.0094 15.9 0.0 0.031 14.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU16487.1 - 0.046 13.3 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Sec62 PF03839.16 OEU16488.1 - 0.11 12.0 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4083 PF13314.6 OEU16488.1 - 0.32 11.0 1.6 0.78 9.7 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) SKICH PF17751.1 OEU16488.1 - 0.55 10.8 2.7 0.86 10.2 0.0 2.5 2 1 1 3 3 3 0 SKICH domain Roughex PF06020.11 OEU16488.1 - 1.1 8.3 10.1 2.2 7.3 10.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Lin-8 PF03353.15 OEU16488.1 - 4.8 6.7 19.2 10 5.6 19.2 1.6 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist FKBP_C PF00254.28 OEU16489.1 - 1.3e-33 115.2 0.0 1.5e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ETRAMP PF09716.10 OEU16490.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) 4HB_MCP_1 PF12729.7 OEU16491.1 - 0.17 11.4 1.2 0.39 10.2 1.2 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Menin PF05053.13 OEU16491.1 - 6.8 4.9 6.8 9.2 4.5 6.8 1.2 1 0 0 1 1 1 0 Menin Ribosomal_L34e PF01199.18 OEU16492.1 - 0.014 15.7 1.2 0.028 14.7 1.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L34e BioT2 PF15368.6 OEU16492.1 - 1.6 8.6 8.3 7 6.6 5.0 2.2 1 1 1 2 2 2 0 Spermatogenesis family BioT2 LRR_8 PF13855.6 OEU16494.1 - 2.2e-20 72.1 18.3 8.7e-07 28.6 0.7 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU16494.1 - 3.6e-12 46.3 21.2 0.00036 20.9 0.3 3.5 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU16494.1 - 2.8e-08 33.2 20.1 0.63 10.8 0.0 6.3 6 0 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 OEU16494.1 - 0.026 14.6 23.6 4.2 7.7 0.3 6.0 6 0 0 6 6 6 0 Leucine Rich repeat SET PF00856.28 OEU16495.1 - 3.6e-07 30.7 0.0 6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 SET domain Rad60-SLD_2 PF13881.6 OEU16497.1 - 5.4e-13 49.0 0.0 7.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OEU16497.1 - 0.0003 20.5 0.0 0.00084 19.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family PI3K_rbd PF00794.18 OEU16497.1 - 0.057 13.6 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF2407 PF10302.9 OEU16497.1 - 0.094 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TerC PF03741.16 OEU16498.1 - 8.3e-47 159.2 7.1 1.4e-46 158.5 7.1 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family PP2C PF00481.21 OEU16500.1 - 1.1e-34 120.2 0.0 3.3e-34 118.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU16500.1 - 0.00019 21.4 0.0 0.021 14.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF4601 PF15373.6 OEU16500.1 - 0.074 12.0 0.2 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) cNMP_binding PF00027.29 OEU16501.1 - 7.8e-27 93.2 0.5 2.5e-13 49.9 0.1 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ribosomal_S25 PF03297.15 OEU16501.1 - 0.066 13.4 1.9 0.16 12.2 1.2 1.9 2 0 0 2 2 2 0 S25 ribosomal protein CALM_bind PF16025.5 OEU16501.1 - 0.42 11.1 1.4 0.68 10.4 1.4 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Pkinase PF00069.25 OEU16502.1 - 9.7e-12 44.8 0.0 1.1e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU16502.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU16502.1 - 0.042 13.2 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU16502.1 - 0.056 13.4 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 OEU16503.1 - 1.7e-34 119.4 0.1 5.4e-34 117.7 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family FIST_C PF10442.9 OEU16504.1 - 1.3e-07 31.7 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 FIST C domain ubiquitin PF00240.23 OEU16505.1 - 1e-05 25.2 0.0 8.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 OEU16505.1 - 0.22 11.5 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DENN PF02141.21 OEU16507.1 - 1.8e-48 165.0 1.7 4.2e-48 163.8 1.7 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain ArfGap PF01412.18 OEU16507.1 - 2.9e-10 40.2 2.5 7.6e-08 32.4 0.0 2.9 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf uDENN PF03456.18 OEU16507.1 - 2.3e-09 37.9 2.1 2.3e-09 37.9 2.1 2.6 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OEU16507.1 - 2.6e-09 36.9 0.6 5.8e-09 35.8 0.6 1.6 1 0 0 1 1 1 1 dDENN domain IQ PF00612.27 OEU16507.1 - 0.002 17.8 0.1 0.002 17.8 0.1 4.1 4 0 0 4 4 4 2 IQ calmodulin-binding motif DUF3490 PF11995.8 OEU16507.1 - 0.018 14.8 0.8 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) FKBP_C PF00254.28 OEU16508.1 - 3.1e-19 69.1 0.0 3.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TGT PF01702.18 OEU16509.1 - 1.5e-96 323.7 0.0 4.5e-71 239.8 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase WD40 PF00400.32 OEU16510.1 - 1.7e-27 95.1 24.0 9e-06 26.3 0.2 7.3 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU16510.1 - 3.1e-10 40.2 0.1 0.008 16.5 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 OEU16510.1 - 1.9e-07 30.5 0.1 4.3e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 OEU16510.1 - 2.7e-06 26.6 1.1 0.00038 19.5 0.2 3.3 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OEU16510.1 - 0.13 10.9 6.2 2.1 6.9 0.2 4.3 2 2 3 5 5 5 0 Nucleoporin Nup120/160 DUF2773 PF10971.8 OEU16510.1 - 0.14 12.3 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) DNA_topoisoIV PF00521.20 OEU16511.1 - 1.1e-111 373.8 0.0 1.5e-111 373.3 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OEU16511.1 - 1.7e-38 131.8 1.2 4.5e-38 130.4 1.2 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OEU16511.1 - 8.1e-16 58.0 0.0 1.7e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OEU16511.1 - 3.6e-10 40.3 0.0 1.7e-09 38.2 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OEU16511.1 - 3.5e-08 33.6 0.0 1.4e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 Toprim domain RRM_Rrp7 PF17799.1 OEU16511.1 - 0.063 13.1 0.3 0.2 11.4 0.3 1.9 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Aldo_ket_red PF00248.21 OEU16512.1 - 2.1e-25 89.6 0.4 1e-23 84.0 0.1 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family Aminotran_1_2 PF00155.21 OEU16514.1 - 9.9e-41 140.1 0.0 1.2e-40 139.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II T6SS-SciN PF12790.7 OEU16514.1 - 0.059 13.1 0.0 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 PAP_fibrillin PF04755.12 OEU16515.1 - 7.1e-07 29.4 0.3 0.00044 20.3 0.0 2.4 2 1 0 2 2 2 2 PAP_fibrillin Slu7 PF11708.8 OEU16515.1 - 0.051 13.3 3.5 0.072 12.8 3.5 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor CDC45 PF02724.14 OEU16515.1 - 0.2 9.9 3.1 0.23 9.7 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 OEU16515.1 - 0.24 11.6 5.7 0.67 10.2 5.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 OEU16515.1 - 1.8 7.6 11.5 2.4 7.2 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 OEU16515.1 - 2.1 8.4 9.7 3 7.9 9.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 OEU16515.1 - 4.7 6.5 9.4 6.6 6.0 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 OEU16515.1 - 4.7 7.6 10.9 1.8 9.0 8.4 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 OEU16515.1 - 5.3 5.5 8.9 6.8 5.1 8.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OEU16515.1 - 6.4 4.7 12.5 7.9 4.4 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi TTL PF03133.15 OEU16516.1 - 1.7e-14 53.7 0.0 1.1e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OEU16516.1 - 1.1e-05 24.9 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.11 OEU16516.1 - 0.016 14.8 0.0 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 OEU16516.1 - 0.064 12.5 0.0 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OEU16516.1 - 0.12 12.4 0.0 7.7 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Amino_oxidase PF01593.24 OEU16517.1 - 5e-30 105.2 0.0 6.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU16517.1 - 1e-11 44.9 0.0 2.7e-11 43.6 0.0 1.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU16517.1 - 8.6e-10 38.7 0.5 3.1e-05 23.7 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU16517.1 - 8.8e-07 28.3 0.8 0.00026 20.2 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 OEU16517.1 - 5.7e-06 25.3 2.3 0.0012 17.6 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OEU16517.1 - 8.5e-06 25.4 1.6 1.3e-05 24.7 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU16517.1 - 7.1e-05 22.2 0.6 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OEU16517.1 - 0.0016 17.8 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OEU16517.1 - 0.0019 18.2 0.1 0.0046 16.9 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OEU16517.1 - 0.0026 18.3 0.5 0.38 11.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU16517.1 - 0.0051 16.1 0.2 0.011 15.0 0.2 1.4 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 OEU16517.1 - 0.0086 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 MCRA family GIDA PF01134.22 OEU16517.1 - 0.054 12.6 0.2 0.097 11.7 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Peripla_BP_3 PF13377.6 OEU16517.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain HEV_ORF1 PF02444.16 OEU16518.1 - 0.43 11.2 3.2 0.75 10.4 3.2 1.4 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) ORC2 PF04084.14 OEU16519.1 - 3.3e-44 151.1 0.2 4.7e-44 150.7 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF111 PF01969.17 OEU16521.1 - 1.8e-39 135.9 0.4 1.5e-37 129.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function DUF111 PPR_2 PF13041.6 OEU16522.1 - 5.2e-18 65.0 0.0 1.3e-07 31.7 0.1 4.6 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.20 OEU16522.1 - 1.4e-16 59.5 2.6 0.00049 20.2 0.1 7.6 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 OEU16522.1 - 7.5e-08 32.3 0.0 0.061 13.4 0.0 4.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU16522.1 - 0.00016 21.3 0.0 2.7 7.8 0.0 4.9 6 0 0 6 6 6 2 PPR repeat TPR_7 PF13176.6 OEU16522.1 - 0.002 18.0 0.0 2.6 8.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Smr PF01713.21 OEU16522.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Smr domain TPR_14 PF13428.6 OEU16522.1 - 0.096 13.6 0.0 23 6.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FA_desaturase_2 PF03405.14 OEU16523.1 - 5.6e-132 439.5 0.0 6.6e-132 439.3 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase FtsJ PF01728.19 OEU16524.1 - 3.6e-66 222.6 0.0 4.4e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Aminotran_1_2 PF00155.21 OEU16525.1 - 1.7e-19 70.3 0.0 3.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II RCC1 PF00415.18 OEU16526.1 - 3.3e-48 162.1 3.9 9.5e-09 35.8 0.0 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU16526.1 - 9.7e-26 89.0 31.1 7.4e-06 25.6 0.4 7.9 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Arf PF00025.21 OEU16527.1 - 1.4e-79 265.6 0.0 1.6e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OEU16527.1 - 9.7e-15 54.8 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OEU16527.1 - 9.2e-13 48.0 0.0 1.1e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OEU16527.1 - 9.4e-13 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OEU16527.1 - 8.6e-12 44.9 0.7 8.8e-08 31.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OEU16527.1 - 2.8e-09 36.7 0.0 3.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU16527.1 - 1.8e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OEU16527.1 - 0.0093 15.3 0.2 0.02 14.2 0.1 1.5 1 1 0 2 2 2 1 6-phosphofructo-2-kinase Ebp2 PF05890.12 OEU16528.1 - 1.9e-34 119.4 4.8 2.3e-34 119.2 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 AA_kinase PF00696.28 OEU16529.1 - 4.7e-44 150.8 1.7 6.2e-44 150.4 1.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family TP6A_N PF04406.14 OEU16530.1 - 1.4e-20 73.0 0.1 3.1e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Aa_trans PF01490.18 OEU16531.1 - 5.2e-15 55.1 20.7 2.8e-09 36.2 11.6 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF3742 PF12553.8 OEU16531.1 - 0.22 11.6 2.2 1.8 8.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DGF-1_C PF11040.8 OEU16532.1 - 0.13 12.3 1.3 0.24 11.4 1.3 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus ATP-synt_B PF00430.18 OEU16532.1 - 0.35 11.0 2.9 0.24 11.5 0.6 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Spem1 PF15670.5 OEU16532.1 - 0.94 9.0 3.3 1.4 8.5 3.3 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 muHD PF10291.9 OEU16533.1 - 1.5e-11 44.3 0.0 7.1e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 OEU16533.1 - 4.7e-09 36.0 0.1 8.8e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Myb_DNA-binding PF00249.31 OEU16534.1 - 5.2e-19 68.2 1.8 2.1e-10 40.6 0.2 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU16534.1 - 2.2e-17 63.1 2.3 1e-11 44.9 0.3 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU16534.1 - 6.6e-05 22.7 0.2 0.00012 21.9 0.2 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OEU16534.1 - 6.8e-05 23.2 0.8 0.0023 18.3 0.1 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OEU16534.1 - 0.19 11.8 1.6 0.36 11.0 0.1 2.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NAP PF00956.18 OEU16535.1 - 2.2e-64 217.3 0.0 2.5e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) ING PF12998.7 OEU16535.1 - 0.0087 16.6 1.4 0.016 15.8 1.4 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Phage_Mu_Gam PF07352.12 OEU16535.1 - 0.062 13.2 2.1 0.11 12.4 2.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein FCH PF00611.23 OEU16535.1 - 0.063 13.6 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 OEU16535.1 - 0.082 13.3 2.5 0.14 12.5 2.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MoaE PF02391.17 OEU16536.1 - 6.3e-35 119.9 0.0 7.5e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Rft-1 PF04506.13 OEU16538.1 - 1e-81 275.3 10.4 1.2e-81 275.0 10.4 1.1 1 0 0 1 1 1 1 Rft protein GREB1 PF15782.5 OEU16539.1 - 4.6 4.2 17.4 6.2 3.8 17.4 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Clathrin PF00637.20 OEU16540.1 - 0.0087 15.9 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS Pkinase PF00069.25 OEU16541.1 - 1.6e-76 257.2 0.0 2.9e-76 256.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16541.1 - 2.9e-42 144.8 0.0 1.5e-41 142.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU16541.1 - 6e-10 38.9 0.0 1.7e-09 37.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like AdenylateSensor PF16579.5 OEU16541.1 - 7.5e-10 39.3 1.4 2e-08 34.7 1.4 3.0 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase KA1 PF02149.19 OEU16541.1 - 2.4e-05 24.0 0.0 7.1e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 OEU16541.1 - 0.0058 15.6 0.2 0.011 14.7 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OEU16541.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPR_1 PF00515.28 OEU16542.1 - 2.3e-30 103.1 4.4 7e-07 28.8 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU16542.1 - 9e-26 87.9 4.4 8e-06 25.6 0.1 6.6 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 OEU16542.1 - 1.5e-19 69.4 5.0 0.00013 21.6 0.0 6.2 4 1 2 6 6 6 4 TPR repeat TPR_14 PF13428.6 OEU16542.1 - 2.2e-19 68.5 1.5 0.0029 18.3 0.1 6.5 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16542.1 - 5.4e-18 63.6 1.9 0.00074 19.5 0.0 6.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OEU16542.1 - 1.4e-17 64.0 0.4 0.00069 20.2 0.0 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU16542.1 - 9.2e-17 59.8 0.4 0.0002 21.2 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OEU16542.1 - 6.9e-16 58.5 2.9 5.2e-05 23.7 0.1 4.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16542.1 - 3e-15 55.4 15.4 0.004 17.4 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 OEU16542.1 - 1.4e-12 47.7 2.9 0.0007 19.8 0.0 4.3 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 OEU16542.1 - 8.3e-11 41.8 0.1 0.67 10.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 OEU16542.1 - 9.4e-09 35.3 0.7 0.16 12.2 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 OEU16542.1 - 0.00012 22.3 3.0 0.5 10.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 OEU16542.1 - 0.00015 21.1 1.0 1.1 8.4 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16542.1 - 0.00076 19.3 5.2 0.46 10.4 0.2 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.12 OEU16542.1 - 0.001 19.0 0.0 1.9 8.6 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU16542.1 - 0.014 15.5 0.3 7.1 6.8 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Clathrin PF00637.20 OEU16542.1 - 0.031 14.1 1.8 5 7.0 0.0 3.7 4 0 0 4 4 4 0 Region in Clathrin and VPS ANAPC3 PF12895.7 OEU16542.1 - 0.067 13.4 2.7 8.5 6.7 0.0 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RRM_1 PF00076.22 OEU16544.1 - 2.3e-08 33.7 0.1 7.2e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEX13 PF15186.6 OEU16544.1 - 0.73 9.5 4.8 2.8 7.6 0.6 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Adaptin_N PF01602.20 OEU16545.1 - 2.9e-92 309.9 0.0 4.4e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OEU16545.1 - 1e-17 64.6 0.1 1e-14 54.9 0.0 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OEU16545.1 - 4.4e-10 38.9 3.9 0.18 12.1 0.1 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 OEU16545.1 - 7.4e-07 29.5 0.1 0.071 13.5 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 OEU16545.1 - 0.0014 18.8 0.3 6.6 7.0 0.0 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OEU16545.1 - 0.0022 18.4 0.6 1.3 9.6 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat RasGEF_N_2 PF14663.6 OEU16545.1 - 0.0027 18.1 0.5 1.7 9.0 0.0 3.0 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.7 OEU16545.1 - 0.097 13.0 0.1 0.76 10.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion GATase_5 PF13507.6 OEU16546.1 - 1.5e-108 361.9 0.0 2.1e-108 361.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OEU16546.1 - 4.9e-35 121.0 0.7 1.6e-19 70.6 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 OEU16546.1 - 1.3e-11 44.9 0.0 3.2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain FGAR-AT_N PF18076.1 OEU16546.1 - 5.5e-09 36.0 0.1 9.6e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal AIRS PF00586.24 OEU16546.1 - 0.00023 21.8 0.3 0.0012 19.4 0.0 2.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Cyclin_N PF00134.23 OEU16547.1 - 9.7e-18 64.1 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU16547.1 - 5.5e-07 29.7 0.5 1.3e-06 28.5 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Thioredoxin_7 PF13899.6 OEU16548.1 - 7.1e-14 51.8 0.0 2.2e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 OEU16548.1 - 2.7e-13 49.5 0.0 4.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OEU16548.1 - 2e-11 43.9 0.0 3.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain IFT57 PF10498.9 OEU16548.1 - 0.33 9.9 2.1 0.28 10.1 0.1 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Med3 PF11593.8 OEU16548.1 - 0.68 9.1 7.8 1.6 7.8 7.8 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2457 PF10446.9 OEU16548.1 - 3.3 6.8 15.9 1.1 8.3 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FYDLN_acid PF09538.10 OEU16548.1 - 5.9 7.6 12.4 16 6.2 7.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 OEU16548.1 - 6.2 7.3 22.9 8.7 6.8 3.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain E1_dh PF00676.20 OEU16549.1 - 7.4e-85 284.5 0.0 8.4e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 OEU16549.1 - 2.6e-06 26.6 0.0 5.4e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 OEU16549.1 - 0.00021 21.1 0.1 0.0015 18.3 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Chloroa_b-bind PF00504.21 OEU16551.1 - 9.9e-31 107.4 0.3 1.3e-30 107.0 0.3 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 OEU16552.1 - 1.3e-30 107.1 0.0 1.8e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RNA_pol_Rpb2_6 PF00562.28 OEU16553.1 - 6.5e-115 384.3 0.3 1.1e-114 383.5 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OEU16553.1 - 2.4e-32 112.1 0.0 5e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OEU16553.1 - 5.9e-27 93.6 0.0 1.4e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 OEU16553.1 - 8.1e-19 67.4 0.0 2e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 OEU16553.1 - 4.6e-16 59.0 0.2 1.3e-14 54.4 0.2 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OEU16553.1 - 7.4e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 zf-C3HC4_3 PF13920.6 OEU16554.1 - 3.3e-08 33.2 8.3 6.3e-08 32.4 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU16554.1 - 6.8e-05 22.7 9.6 0.00013 21.9 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU16554.1 - 0.00071 19.6 2.3 0.0023 17.9 2.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OEU16554.1 - 0.0023 17.6 0.8 0.0023 17.6 0.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 OEU16554.1 - 0.012 16.0 9.4 0.024 14.9 9.4 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OEU16554.1 - 0.77 9.7 7.0 1.8 8.5 7.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cwf_Cwc_15 PF04889.12 OEU16554.1 - 1.7 8.4 14.6 0.077 12.7 8.8 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4 PF00097.25 OEU16554.1 - 1.8 8.5 9.0 3.8 7.5 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OEU16554.1 - 5 7.0 7.5 9.8 6.1 7.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Presenilin PF01080.17 OEU16554.1 - 5.1 5.8 5.5 1.7 7.4 2.5 1.6 2 0 0 2 2 2 0 Presenilin Bravo_FIGEY PF13882.6 OEU16554.1 - 8 7.9 7.6 11 7.5 3.2 2.8 2 1 0 2 2 2 0 Bravo-like intracellular region PPR_2 PF13041.6 OEU16555.1 - 2.7e-26 91.5 9.8 1.2e-06 28.5 1.2 9.2 8 2 1 9 9 9 5 PPR repeat family PPR_1 PF12854.7 OEU16555.1 - 1.2e-14 53.7 22.6 0.038 13.7 0.7 11.1 12 2 0 12 12 12 5 PPR repeat PPR_3 PF13812.6 OEU16555.1 - 1.9e-12 47.1 0.2 0.097 12.8 0.0 7.6 4 2 3 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU16555.1 - 9.1e-09 35.0 1.7 0.0015 18.0 0.0 4.1 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OEU16555.1 - 9.3e-05 22.4 32.5 0.0041 17.3 0.4 11.6 12 4 0 12 12 12 2 PPR repeat RACo_linker PF17650.1 OEU16555.1 - 0.012 15.5 0.0 0.043 13.7 0.0 2.0 1 0 0 1 1 1 0 RACo linker region V_ATPase_I PF01496.19 OEU16556.1 - 0.25 9.2 0.1 0.33 8.8 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MULE PF10551.9 OEU16557.1 - 3.7e-08 33.7 0.4 5e-07 30.0 0.0 3.2 4 0 0 4 4 4 1 MULE transposase domain SWIM PF04434.17 OEU16557.1 - 0.014 15.1 0.7 0.014 15.1 0.7 2.1 2 0 0 2 2 2 0 SWIM zinc finger DUF520 PF04461.13 OEU16557.1 - 2.3 8.3 5.7 1.4 9.0 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF520) ATP-synt_ab PF00006.25 OEU16558.1 - 1.3e-66 224.3 0.0 1.8e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OEU16558.1 - 3.6e-13 49.8 0.2 6.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OEU16558.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) GWT1 PF06423.12 OEU16559.1 - 0.22 11.7 2.8 1.2 9.2 2.0 2.4 1 1 0 1 1 1 0 GWT1 Anoctamin PF04547.12 OEU16559.1 - 6.3 5.5 12.1 2.8 6.7 1.1 2.6 2 1 1 3 3 3 0 Calcium-activated chloride channel DUF420 PF04238.12 OEU16560.1 - 6.2 7.1 9.8 0.097 13.0 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Ribosomal_L27e PF01777.18 OEU16561.1 - 1.4e-25 89.5 7.0 2.2e-25 88.8 7.0 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OEU16561.1 - 6.6e-06 25.9 1.9 6.6e-06 25.9 1.9 2.1 2 0 0 2 2 2 1 KOW motif MAP65_ASE1 PF03999.12 OEU16564.1 - 4.4e-60 204.0 43.7 2.1e-59 201.8 40.6 2.0 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Apolipoprotein PF01442.18 OEU16564.1 - 0.0092 15.9 6.2 0.0092 15.9 6.2 3.8 3 2 0 3 3 3 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 OEU16564.1 - 0.016 15.2 18.4 0.18 11.9 1.3 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF1818 PF08848.11 OEU16564.1 - 0.087 12.9 2.7 0.15 12.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) DUF148 PF02520.17 OEU16564.1 - 0.64 10.2 15.0 1.6 8.9 0.1 4.6 4 1 1 5 5 5 0 Domain of unknown function DUF148 Carbpep_Y_N PF05388.11 OEU16564.1 - 1.1 9.8 9.4 25 5.4 0.1 4.7 4 2 0 4 4 4 0 Carboxypeptidase Y pro-peptide DUF948 PF06103.11 OEU16564.1 - 2.4 8.5 6.1 65 3.9 0.1 4.2 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 OEU16564.1 - 6.4 6.9 17.4 0.48 10.5 3.1 4.1 4 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) SNF2_N PF00176.23 OEU16565.1 - 1.4e-16 60.2 0.0 7.8e-16 57.7 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OEU16565.1 - 4e-09 36.3 0.0 0.0011 18.5 0.1 3.5 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase ResIII PF04851.15 OEU16565.1 - 0.00038 20.5 0.0 0.0041 17.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1858 PF08984.11 OEU16565.1 - 0.13 12.5 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) Shugoshin_C PF07557.11 OEU16565.1 - 3.9 7.4 6.0 9.4 6.1 6.0 1.7 1 0 0 1 1 1 0 Shugoshin C terminus BCL_N PF04714.13 OEU16566.1 - 0.45 10.6 2.0 1.5 8.9 0.1 2.9 2 0 0 2 2 2 0 BCL7, N-terminal conserver region T2SSM PF04612.12 OEU16566.1 - 0.51 10.4 8.1 8.5 6.4 0.2 3.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M AAA PF00004.29 OEU16567.1 - 2.4e-28 99.2 0.0 5.7e-28 98.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OEU16567.1 - 0.00042 19.7 0.1 0.00071 19.0 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU16567.1 - 0.0015 18.6 0.3 0.024 14.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU16567.1 - 0.004 17.4 0.2 0.026 14.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OEU16567.1 - 0.0093 16.3 0.1 0.02 15.3 0.0 1.6 1 1 0 1 1 1 1 RNA helicase ATPase PF06745.13 OEU16567.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OEU16567.1 - 0.022 15.1 0.2 0.059 13.7 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OEU16567.1 - 0.023 15.2 0.0 0.031 14.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OEU16567.1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU16567.1 - 0.092 13.3 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OEU16567.1 - 0.099 12.2 0.4 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 OEU16567.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 OEU16567.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OEU16567.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OEU16567.1 - 0.17 11.6 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RRM_1 PF00076.22 OEU16568.1 - 5.1e-33 112.7 0.1 3.4e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU16568.1 - 2.1e-14 53.4 0.7 8.7e-07 29.0 0.0 2.7 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OEU16568.1 - 9.5e-05 22.4 0.1 0.38 10.8 0.0 2.6 2 1 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 OEU16568.1 - 0.0041 17.4 0.0 0.4 10.9 0.0 2.4 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Laminin_G_1 PF00054.23 OEU16568.1 - 0.027 14.7 0.0 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain DUF4614 PF15391.6 OEU16568.1 - 0.039 14.0 0.4 0.055 13.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.13 OEU16568.1 - 2.7 8.6 10.3 4.1 8.0 10.3 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DEAD PF00270.29 OEU16569.1 - 1.8e-28 99.5 0.0 5e-28 98.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU16569.1 - 1.3e-18 67.4 0.4 1.4e-17 64.0 0.1 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU16569.1 - 0.00017 21.7 0.0 0.00043 20.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 OEU16569.1 - 0.008 16.5 0.0 22 5.5 0.0 3.7 3 0 0 3 3 3 2 RNA helicase DUF1955 PF09205.10 OEU16569.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1955) YTH PF04146.15 OEU16572.1 - 0.058 13.3 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 YT521-B-like domain DRMBL PF07522.14 OEU16573.1 - 3.7e-23 81.8 0.0 6.3e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OEU16573.1 - 5.2e-05 22.8 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU16573.1 - 0.0019 18.3 1.8 0.021 14.8 1.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OEU16573.1 - 0.042 13.3 0.0 0.46 9.9 0.0 2.1 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OEU16573.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain TRAPPC10 PF12584.8 OEU16574.1 - 4.4e-08 33.0 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_2 PF07719.17 OEU16574.1 - 0.17 12.1 0.6 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.20 OEU16575.1 - 2.5e-96 323.3 0.0 4.1e-96 322.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Ribosomal_L19 PF01245.20 OEU16576.1 - 4.3e-15 55.6 0.9 5e-15 55.4 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Pkinase PF00069.25 OEU16577.1 - 2e-06 27.4 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4267 PF14087.6 OEU16577.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) DHHC PF01529.20 OEU16578.1 - 7.6e-34 116.7 13.4 7.6e-34 116.7 13.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase PGG PF13962.6 OEU16578.1 - 0.051 13.4 2.0 7.5 6.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function Sec15 PF04091.12 OEU16579.1 - 1.3e-15 57.6 0.0 4.6e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like CoaE PF01121.20 OEU16581.1 - 6.1e-20 71.6 0.0 2.6e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase UNC-50 PF05216.13 OEU16582.1 - 0.054 13.0 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 UNC-50 family PEMT PF04191.13 OEU16584.1 - 2.5e-06 27.8 1.1 2.5e-06 27.8 1.1 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF3419 PF11899.8 OEU16585.1 - 1.2e-68 232.1 0.0 2.1e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 OEU16585.1 - 1.6e-15 57.3 0.0 3.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16585.1 - 1.2e-08 35.6 0.0 2.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16585.1 - 8.7e-08 32.8 0.0 1.4e-06 28.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU16585.1 - 1.1e-07 31.5 0.0 3.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU16585.1 - 7.4e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16585.1 - 1.6e-05 25.5 0.0 6.5e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 OEU16585.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PP2C PF00481.21 OEU16586.1 - 9.8e-53 179.4 1.1 1.2e-52 179.2 1.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU16586.1 - 2.7e-07 30.5 0.1 4.3e-07 29.8 0.1 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C IZUMO PF15005.6 OEU16587.1 - 0.082 13.4 0.2 1 9.9 0.0 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated PCI PF01399.27 OEU16588.1 - 5.2e-13 49.4 0.2 2e-12 47.5 0.1 2.2 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 OEU16588.1 - 6.2e-09 35.8 2.0 1.4e-08 34.7 2.0 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_14 PF13428.6 OEU16588.1 - 0.037 14.8 1.2 12 7.1 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rpb6 PF01192.22 OEU16588.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb6 TPR_21 PF09976.9 OEU16588.1 - 1.5 8.5 6.3 0.13 12.0 0.9 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain F-box-like PF12937.7 OEU16589.1 - 0.00033 20.5 0.5 0.00072 19.4 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU16589.1 - 0.0012 18.7 0.2 0.0025 17.6 0.2 1.5 1 0 0 1 1 1 1 F-box domain Methyltransf_31 PF13847.6 OEU16590.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16590.1 - 0.00019 22.0 0.0 0.00034 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OEU16590.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 OEU16590.1 - 0.0042 17.8 0.0 0.0076 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 60KD_IMP PF02096.20 OEU16592.1 - 1.2e-30 106.6 0.9 1.4e-30 106.4 0.9 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein Caa3_CtaG PF09678.10 OEU16592.1 - 0.0066 15.9 0.9 0.015 14.8 0.7 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) XRN1_D1 PF18332.1 OEU16593.1 - 1.9e-26 93.1 0.0 3.8e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 OEU16593.1 - 9.4e-18 64.1 0.2 2.8e-17 62.6 0.2 1.9 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN_M PF17846.1 OEU16593.1 - 4.1e-06 26.0 0.0 6.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN1_D2_D3 PF18334.1 OEU16593.1 - 0.0037 17.4 0.0 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain XRN_N PF03159.18 OEU16594.1 - 1.7e-71 240.5 0.1 1.9e-71 240.3 0.1 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SNF2_N PF00176.23 OEU16596.1 - 1.5e-50 171.9 0.6 1.5e-50 171.9 0.6 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU16596.1 - 2.1e-19 69.9 1.5 4.1e-16 59.3 0.0 3.8 4 1 1 5 5 5 2 Helicase conserved C-terminal domain ResIII PF04851.15 OEU16596.1 - 1.1e-11 45.0 0.0 3.6e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OEU16596.1 - 6.2e-05 22.8 0.6 0.00036 20.3 0.0 2.3 2 1 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 OEU16596.1 - 0.00027 20.8 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 OEU16596.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.9 2 0 0 2 2 2 0 DEAD_2 ERCC3_RAD25_C PF16203.5 OEU16596.1 - 0.02 14.1 0.7 0.5 9.5 0.0 2.8 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 OEU16596.1 - 0.067 13.5 0.1 3.2 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AzlD PF05437.12 OEU16596.1 - 0.079 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) AAA_14 PF13173.6 OEU16596.1 - 0.097 12.7 0.2 0.69 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 OEU16597.1 - 0.02 15.0 0.1 0.065 13.4 0.0 1.8 2 0 0 2 2 2 0 DnaJ domain DUF3271 PF11675.8 OEU16597.1 - 0.24 10.6 0.4 0.34 10.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Lentiviral_Tat PF02998.14 OEU16597.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein Ribosomal_L37 PF08561.10 OEU16598.1 - 4.3e-09 36.9 1.7 1.4e-06 28.8 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DUF885 PF05960.11 OEU16599.1 - 1.8e-132 443.7 0.0 2e-132 443.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) SEP PF08059.13 OEU16599.1 - 0.12 12.9 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 SEP domain IRK_C PF17655.1 OEU16600.1 - 1.8e-16 60.2 0.0 1.5e-06 28.0 0.0 3.3 2 1 1 3 3 3 3 Inward rectifier potassium channel C-terminal domain UDG PF03167.19 OEU16601.1 - 1.8e-18 67.0 0.1 2e-17 63.6 0.1 2.2 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_S21 PF01165.20 OEU16602.1 - 0.016 14.9 0.4 0.041 13.6 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 FAT PF02259.23 OEU16603.1 - 1.5e-34 119.7 4.7 3.4e-34 118.6 4.7 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OEU16603.1 - 9.8e-15 55.0 1.1 5.6e-14 52.5 0.1 2.6 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OEU16603.1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain AbiH PF14253.6 OEU16603.1 - 0.12 12.3 1.2 1.1 9.1 0.2 3.0 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH ERp29 PF07749.12 OEU16603.1 - 4.7 8.2 6.7 6.7 7.7 0.1 4.1 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain BSD PF03909.17 OEU16605.1 - 0.00015 21.7 0.0 0.00046 20.1 0.0 1.8 1 0 0 1 1 1 1 BSD domain Tim54 PF11711.8 OEU16605.1 - 0.015 14.1 4.9 0.028 13.2 4.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 OEU16605.1 - 0.42 8.9 8.7 0.75 8.0 8.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Epimerase PF01370.21 OEU16606.1 - 9.5e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 OEU16607.1 - 6.3e-20 71.7 0.0 2e-10 40.5 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 OEU16607.1 - 7.9e-08 32.3 0.7 6.2e-07 29.3 0.1 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU16607.1 - 2.6e-05 24.3 0.0 7.7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OEU16607.1 - 3.7e-05 22.9 0.1 0.00071 18.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 OEU16607.1 - 7.2e-05 22.2 0.3 0.0005 19.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU16607.1 - 0.00022 20.4 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OEU16607.1 - 0.0016 17.8 0.0 0.023 14.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OEU16607.1 - 0.038 12.7 0.1 0.07 11.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 OEU16607.1 - 0.053 12.4 0.1 2.1 7.1 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 OEU16607.1 - 0.058 14.0 0.0 0.22 12.1 0.0 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU16607.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OEU16607.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OEU16607.1 - 0.15 11.3 0.1 0.49 9.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF711 PF05167.12 OEU16608.1 - 3.6e-50 171.0 0.0 6.5e-50 170.2 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised ACR (DUF711) Pico_P1A PF02226.16 OEU16608.1 - 0.37 10.9 1.7 0.58 10.2 0.0 2.1 3 0 0 3 3 3 0 Picornavirus coat protein (VP4) DUF4191 PF13829.6 OEU16609.1 - 0.14 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DEAD PF00270.29 OEU16610.1 - 3.9e-33 114.7 0.0 8.3e-33 113.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU16610.1 - 1.8e-22 79.8 0.2 5.1e-21 75.1 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU16610.1 - 4.3e-06 26.1 0.1 1.1e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OEU16610.1 - 0.001 19.1 0.1 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myco_arth_vir_N PF09610.10 OEU16610.1 - 0.38 10.9 3.4 0.26 11.4 1.4 1.8 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Aminotran_5 PF00266.19 OEU16611.1 - 6.4e-26 91.2 1.1 4.7e-19 68.6 0.9 3.1 1 1 0 2 2 2 2 Aminotransferase class-V TTL PF03133.15 OEU16611.1 - 1.2e-21 77.2 0.0 3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family COPIIcoated_ERV PF07970.12 OEU16612.1 - 3.2e-68 229.9 0.0 4.6e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OEU16612.1 - 4.1e-18 65.5 0.3 1.1e-17 64.1 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Rotamase PF00639.21 OEU16613.1 - 0.091 13.7 2.1 5.8 7.9 0.5 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Peptidase_C3 PF00548.20 OEU16613.1 - 0.16 11.9 0.3 0.31 11.0 0.3 1.5 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) PRIMA1 PF16101.5 OEU16613.1 - 1.4 9.0 11.3 2.2 8.3 10.4 1.8 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 ArfGap PF01412.18 OEU16615.1 - 1.3e-30 105.9 1.5 3.6e-30 104.4 1.5 1.6 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_C78 PF07910.13 OEU16616.1 - 2.5e-17 63.1 14.5 1.4e-15 57.3 9.8 3.8 2 1 0 2 2 2 1 Peptidase family C78 60KD_IMP PF02096.20 OEU16617.1 - 5.4e-15 55.7 3.0 6.4e-14 52.2 0.1 2.6 2 1 0 2 2 2 1 60Kd inner membrane protein Armet PF10208.9 OEU16618.1 - 2.7e-25 89.0 9.9 4.3e-25 88.3 9.9 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding HeH PF12949.7 OEU16618.1 - 1.2e-05 25.0 0.3 2.4e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 OEU16618.1 - 0.002 17.8 0.3 0.0045 16.7 0.3 1.6 1 0 0 1 1 1 1 SAP domain DHR10 PF18595.1 OEU16618.1 - 2.8 8.0 6.3 2.2 8.4 0.7 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain AAA PF00004.29 OEU16619.1 - 4.1e-37 127.5 0.0 7.7e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU16619.1 - 4.1e-09 36.1 0.0 8.8e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OEU16619.1 - 1.1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU16619.1 - 1.3e-05 25.5 1.1 0.0035 17.6 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 OEU16619.1 - 4.1e-05 23.6 0.2 0.00085 19.3 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU16619.1 - 4.4e-05 23.9 2.5 0.013 15.9 0.1 3.1 1 1 0 3 3 3 1 AAA ATPase domain Vps4_C PF09336.10 OEU16619.1 - 7.4e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 OEU16619.1 - 0.0001 22.5 0.0 0.00025 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OEU16619.1 - 0.00017 21.8 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OEU16619.1 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OEU16619.1 - 0.00097 18.6 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OEU16619.1 - 0.0016 18.2 0.1 0.0088 15.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 OEU16619.1 - 0.0019 17.5 0.4 0.0073 15.5 0.1 2.0 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 OEU16619.1 - 0.0022 18.0 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU16619.1 - 0.0025 18.3 0.0 0.011 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 OEU16619.1 - 0.013 15.0 0.0 1.7 8.0 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OEU16619.1 - 0.027 14.0 0.2 0.11 12.0 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OEU16619.1 - 0.033 13.6 0.2 0.08 12.4 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein Bac_DnaA PF00308.18 OEU16619.1 - 0.036 13.9 0.1 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_25 PF13481.6 OEU16619.1 - 0.038 13.5 0.9 0.17 11.5 0.9 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU16619.1 - 0.04 14.2 0.2 0.091 13.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 OEU16619.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 OEU16619.1 - 0.048 13.0 0.1 0.19 11.1 0.1 2.0 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 OEU16619.1 - 0.068 13.1 0.2 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Hydin_ADK PF17213.3 OEU16619.1 - 0.07 13.4 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 OEU16619.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 OEU16619.1 - 0.086 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 OEU16619.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase TPR_12 PF13424.6 OEU16620.1 - 3.2e-41 139.5 10.5 2.2e-13 50.3 0.1 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16620.1 - 1.8e-26 91.2 12.9 0.00016 21.4 0.1 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16620.1 - 6.9e-25 85.8 8.6 2.6e-05 23.8 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16620.1 - 5.5e-24 82.3 10.7 0.00099 19.1 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 OEU16620.1 - 7.1e-21 72.6 8.8 0.0064 16.5 0.1 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 OEU16620.1 - 1.3e-13 49.9 9.3 6.5e-05 22.7 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU16620.1 - 3.1e-11 42.8 7.0 0.0056 16.3 0.0 6.6 7 1 1 8 8 8 3 TPR repeat TPR_14 PF13428.6 OEU16620.1 - 1.9e-07 31.3 12.7 4.8 8.3 0.1 6.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU16620.1 - 2.3e-07 30.5 3.8 0.00027 20.4 0.1 2.7 1 1 1 2 2 2 2 MalT-like TPR region SNAP PF14938.6 OEU16620.1 - 3.8e-07 29.8 0.1 0.008 15.6 0.1 3.3 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 OEU16620.1 - 0.0064 16.5 5.2 3.7 7.7 0.0 4.7 4 1 1 5 5 5 1 MIT (microtubule interacting and transport) domain CHDCT2 PF08074.11 OEU16620.1 - 0.0093 16.2 1.7 1.9 8.6 0.2 2.1 2 0 0 2 2 2 2 CHDCT2 (NUC038) domain TPR_6 PF13174.6 OEU16620.1 - 0.016 15.8 7.0 1.2e+02 3.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 OEU16620.1 - 0.025 15.2 0.1 7.9 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 OEU16620.1 - 0.033 14.2 0.3 8.2 6.5 0.0 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF627) TPR_17 PF13431.6 OEU16620.1 - 0.067 13.6 4.7 13 6.5 0.0 5.2 6 1 1 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 OEU16620.1 - 0.31 10.7 3.1 5.4 6.7 0.2 3.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 OEU16620.1 - 0.38 10.4 2.5 23 4.6 0.2 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 OEU16620.1 - 0.66 10.1 3.7 88 3.3 0.0 4.5 1 1 5 6 6 6 0 Anaphase-promoting complex subunit 5 CorA PF01544.18 OEU16620.1 - 1.7 7.9 7.6 2.3 7.4 1.5 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ProRS-C_1 PF09180.11 OEU16621.1 - 1.1e-21 76.8 1.8 1.7e-21 76.2 0.1 2.3 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OEU16621.1 - 1.9e-20 73.6 0.0 3.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OEU16621.1 - 2.5e-11 43.6 0.0 6.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 OEU16621.1 - 1.2e-10 41.3 3.7 1.2e-10 41.3 3.7 2.0 2 0 0 2 2 2 1 WHEP-TRS domain DUF724 PF05266.14 OEU16621.1 - 0.002 18.0 2.7 0.0042 16.9 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF1764 PF08576.10 OEU16621.1 - 0.044 14.7 5.3 0.21 12.5 5.3 2.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Med3 PF11593.8 OEU16621.1 - 0.12 11.6 6.7 0.24 10.5 6.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RP-C_C PF11800.8 OEU16621.1 - 1 9.4 5.3 0.31 11.1 2.2 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region CobT PF06213.12 OEU16621.1 - 2.1 7.7 8.3 4 6.8 8.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ig_5 PF16681.5 OEU16622.1 - 0.054 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain K_channel_TID PF07941.11 OEU16623.1 - 0.014 15.8 4.8 0.014 15.8 4.8 2.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Mpv17_PMP22 PF04117.12 OEU16624.1 - 1.2e-16 60.6 0.2 3.4e-16 59.2 0.2 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family UBA PF00627.31 OEU16625.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain CDC45 PF02724.14 OEU16626.1 - 9.9e-151 503.2 0.2 1.1e-150 503.0 0.2 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 OEU16626.1 - 1e-06 28.5 7.6 1.5e-06 27.9 7.6 1.2 1 0 0 1 1 1 1 SDA1 Presenilin PF01080.17 OEU16626.1 - 0.08 11.7 2.4 0.15 10.8 2.4 1.3 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 OEU16626.1 - 0.76 8.1 16.9 1.3 7.4 16.9 1.3 1 0 0 1 1 1 0 Mpp10 protein Pkinase PF00069.25 OEU16627.1 - 7e-56 189.5 0.0 8e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16627.1 - 2.6e-27 95.8 0.0 3.1e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU16627.1 - 2.1e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU16627.1 - 0.02 14.8 0.0 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OEU16627.1 - 0.031 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_3 PF00202.21 OEU16629.1 - 4.5e-71 239.7 0.0 5.4e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OEU16629.1 - 0.0012 18.1 0.0 0.64 9.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OEU16629.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase PHTB1_N PF14727.6 OEU16629.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 PTHB1 N-terminus FKBP_C PF00254.28 OEU16630.1 - 2.9e-25 88.4 0.0 4.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 OEU16630.1 - 2e-05 25.5 0.1 5.6e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Fungus-induced PF10917.8 OEU16630.1 - 0.017 15.4 0.2 0.017 15.4 0.2 1.8 2 0 0 2 2 2 0 Fungus-induced protein SUI1 PF01253.22 OEU16631.1 - 1.1e-14 54.7 3.6 1.8e-14 54.0 3.6 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 CDC45 PF02724.14 OEU16631.1 - 0.083 11.2 2.1 0.11 10.8 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3335 PF11814.8 OEU16631.1 - 0.16 11.4 0.3 0.24 10.8 0.3 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Pox_Ag35 PF03286.14 OEU16631.1 - 1.1 9.0 6.9 1.9 8.3 6.9 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein PGA2 PF07543.12 OEU16631.1 - 1.8 8.5 7.4 0.56 10.2 2.4 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Spt5_N PF11942.8 OEU16631.1 - 2.2 9.3 12.9 0.42 11.6 5.5 2.6 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.13 OEU16631.1 - 4.4 7.3 9.5 6.1 6.9 9.5 1.3 1 1 0 1 1 1 0 YL1 nuclear protein SPC22 PF04573.12 OEU16632.1 - 0.13 11.8 0.6 0.31 10.5 0.1 1.9 2 0 0 2 2 2 0 Signal peptidase subunit DUF1391 PF07151.12 OEU16632.1 - 0.3 10.9 1.5 0.74 9.7 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) DUF4499 PF14934.6 OEU16633.1 - 0.0015 18.8 0.6 0.003 17.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 OEU16633.1 - 0.018 15.6 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) PH PF00169.29 OEU16634.1 - 1.4e-08 35.2 0.0 2.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PGP_phosphatase PF09419.10 OEU16635.1 - 8.3e-36 123.1 0.0 1.1e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OEU16635.1 - 0.0007 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OEU16635.1 - 0.0017 18.7 0.1 0.15 12.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Abhydrolase_3 PF07859.13 OEU16636.1 - 3.3e-16 59.8 0.0 4.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DnaJ PF00226.31 OEU16637.1 - 1.1e-19 70.2 0.6 1.3e-19 70.1 0.6 1.0 1 0 0 1 1 1 1 DnaJ domain Methyltransf_11 PF08241.12 OEU16638.1 - 0.00026 21.6 0.0 0.00038 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16638.1 - 0.00047 20.8 0.2 0.00066 20.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16638.1 - 0.0094 16.6 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain LRR_8 PF13855.6 OEU16639.1 - 1.2e-31 108.2 54.6 2.9e-07 30.1 4.4 10.2 8 3 0 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 OEU16639.1 - 7.1e-30 102.6 57.3 1.6e-05 25.1 0.3 13.2 7 4 8 15 15 15 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU16639.1 - 1.4e-10 40.2 44.8 1.6 9.6 0.4 17.3 18 2 0 18 18 18 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU16639.1 - 0.0047 16.9 42.6 18 5.7 0.1 14.3 15 0 0 15 15 15 1 Leucine Rich repeat LRRNT_2 PF08263.12 OEU16639.1 - 0.021 15.1 4.4 0.061 13.6 4.4 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Pro_isomerase PF00160.21 OEU16640.1 - 7.7e-45 153.0 0.1 9.7e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peripla_BP_4 PF13407.6 OEU16640.1 - 0.077 12.6 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain GOLD_2 PF13897.6 OEU16641.1 - 0.016 15.7 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking mono-CXXC PF15626.6 OEU16641.1 - 0.095 13.1 3.3 0.21 12.0 3.3 1.5 1 0 0 1 1 1 0 single CXXC unit DUF4366 PF14283.6 OEU16641.1 - 0.2 11.7 9.2 0.033 14.2 5.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) PRP38_assoc PF12871.7 OEU16641.1 - 8.6 7.0 12.1 15 6.3 11.8 1.4 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glu_synthase PF01645.17 OEU16642.1 - 2.7e-150 500.6 0.6 9.5e-150 498.8 0.1 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.21 OEU16642.1 - 8.1e-145 482.7 0.0 7.6e-143 476.2 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 OEU16642.1 - 9.5e-103 343.5 0.0 3.1e-102 341.8 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OEU16642.1 - 5.4e-75 251.2 8.0 9.8e-75 250.3 8.0 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 OEU16642.1 - 4e-05 22.8 1.4 0.00013 21.1 1.4 1.8 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PBECR4 PF18813.1 OEU16642.1 - 0.079 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 DNA_pol_A PF00476.20 OEU16643.1 - 6.5e-70 236.1 0.0 7.4e-68 229.3 0.0 2.8 1 1 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 OEU16643.1 - 4.6e-09 36.2 0.0 3.8e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 3'-5' exonuclease SET PF00856.28 OEU16644.1 - 1.4e-11 45.1 0.0 3.1e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 SET domain 2OG-FeII_Oxy_2 PF13532.6 OEU16645.1 - 1.2e-14 55.0 0.0 2.8e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 OEU16646.1 - 3.5e-17 62.8 0.0 5.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16646.1 - 1.3e-13 51.4 0.0 4.7e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16646.1 - 1e-06 29.4 0.0 1.6e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU16646.1 - 2.3e-06 27.5 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16646.1 - 5.5e-06 26.3 0.0 9.2e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU16646.1 - 0.0075 16.1 1.8 0.048 13.5 1.9 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase IQ PF00612.27 OEU16646.1 - 8.9 6.4 6.4 0.89 9.5 0.7 2.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif Proteasome PF00227.26 OEU16648.1 - 6e-06 25.9 0.1 0.00011 21.8 0.1 2.6 1 1 0 1 1 1 1 Proteasome subunit ABC_ATPase PF09818.9 OEU16650.1 - 3.7e-92 309.5 0.5 3.9e-77 260.0 0.1 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 OEU16650.1 - 0.009 16.5 0.5 0.044 14.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain Yae1_N PF09811.9 OEU16652.1 - 6.8e-06 25.7 2.1 1.1e-05 25.1 2.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SKA2 PF16740.5 OEU16652.1 - 0.011 15.5 0.6 1.9 8.3 0.4 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Peptidase_M3 PF01432.20 OEU16653.1 - 4e-133 445.0 0.0 6.3e-133 444.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OEU16653.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Methyltransf_31 PF13847.6 OEU16654.1 - 1.9e-15 56.9 0.1 3.1e-14 53.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 OEU16654.1 - 2.1e-15 56.8 0.0 7.1e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OEU16654.1 - 2e-14 53.8 0.0 3.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16654.1 - 4.8e-13 49.6 0.0 1.1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16654.1 - 2.6e-11 44.1 0.0 5.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16654.1 - 3.1e-09 37.5 0.0 5.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 OEU16654.1 - 0.00027 20.9 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DOT1 PF08123.13 OEU16654.1 - 0.0023 17.5 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Ubie_methyltran PF01209.18 OEU16654.1 - 0.0057 16.0 0.1 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 OEU16654.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 OEU16654.1 - 0.026 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 OEU16655.1 - 1.2e-12 48.3 0.0 2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16655.1 - 6.4e-11 42.8 0.1 1.6e-10 41.6 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU16655.1 - 3.8e-07 30.0 0.1 4.5e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16655.1 - 5.3e-06 26.4 0.1 1.3e-05 25.2 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16655.1 - 3e-05 24.7 0.0 4.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OEU16655.1 - 0.00066 20.7 0.0 0.0013 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU16655.1 - 0.0008 18.8 0.0 0.016 14.5 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OEU16655.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 OEU16655.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 OEU16656.1 - 2.1e-39 134.7 0.0 3e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OEU16656.1 - 8.3e-07 28.7 0.0 9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OEU16656.1 - 0.0039 17.4 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.32 OEU16657.1 - 1.7e-14 53.9 11.6 0.0026 18.6 1.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU16657.1 - 6e-07 29.7 0.6 0.025 14.9 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 OEU16658.1 - 1.9e-46 158.0 0.0 9.3e-22 78.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU16658.1 - 5.1e-18 65.9 0.1 0.00049 20.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OEU16658.1 - 1e-17 63.9 0.7 1e-17 63.9 0.7 3.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 OEU16658.1 - 2.4e-11 43.5 6.2 0.0049 16.3 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OEU16658.1 - 1e-08 36.0 4.2 0.011 16.2 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OEU16658.1 - 1.8e-08 34.0 0.0 0.0028 17.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 OEU16658.1 - 7e-07 29.7 0.1 0.079 13.4 0.2 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 OEU16658.1 - 2.4e-06 27.5 1.8 0.044 13.5 0.1 3.4 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OEU16658.1 - 3.8e-06 27.2 0.2 0.084 13.1 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OEU16658.1 - 5.1e-06 27.0 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 OEU16658.1 - 7e-06 25.9 0.0 0.19 11.4 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 OEU16658.1 - 7.1e-06 26.4 0.0 0.056 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OEU16658.1 - 1.3e-05 25.2 0.1 0.32 11.0 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 OEU16658.1 - 1.6e-05 25.4 0.2 0.043 14.4 0.0 2.9 2 1 1 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 OEU16658.1 - 2.9e-05 24.0 0.0 0.13 12.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 OEU16658.1 - 3.2e-05 24.1 0.0 0.46 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU16658.1 - 3.5e-05 24.1 0.1 0.75 10.2 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_7 PF12775.7 OEU16658.1 - 8.9e-05 22.1 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OEU16658.1 - 0.00017 21.6 0.1 0.19 11.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 OEU16658.1 - 0.00038 20.5 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 OEU16658.1 - 0.00052 20.0 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 OEU16658.1 - 0.00065 19.5 0.1 0.44 10.3 0.0 2.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OEU16658.1 - 0.00068 19.4 0.9 1.3 8.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 OEU16658.1 - 0.0011 19.2 0.3 2.9 7.9 0.1 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_27 PF13514.6 OEU16658.1 - 0.0021 17.7 0.2 1.5 8.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OEU16658.1 - 0.0023 17.9 0.0 0.53 10.2 0.0 2.6 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OEU16658.1 - 0.0024 17.8 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OEU16658.1 - 0.0026 17.0 0.0 0.6 9.3 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain Cytidylate_kin PF02224.18 OEU16658.1 - 0.0043 16.8 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase IstB_IS21 PF01695.17 OEU16658.1 - 0.0059 16.3 0.0 2.9 7.6 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein SRP54 PF00448.22 OEU16658.1 - 0.0077 15.9 0.1 1.2 8.7 0.4 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 OEU16658.1 - 0.0089 15.6 0.1 0.87 9.1 0.2 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OEU16658.1 - 0.015 15.0 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 OEU16658.1 - 0.019 15.2 2.6 1.7 8.9 0.0 3.9 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 OEU16658.1 - 0.026 14.6 0.1 3.7 7.6 0.0 3.3 2 1 1 3 3 2 0 Dynamin family Rad17 PF03215.15 OEU16658.1 - 0.028 14.3 0.0 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MukB PF04310.12 OEU16658.1 - 0.029 14.2 1.4 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal Zeta_toxin PF06414.12 OEU16658.1 - 0.034 13.4 0.0 0.83 8.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 OEU16658.1 - 0.042 14.1 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OEU16658.1 - 0.043 13.7 0.7 1.9 8.4 0.2 2.6 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 OEU16658.1 - 0.054 12.9 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OEU16658.1 - 0.091 12.3 0.0 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OEU16658.1 - 0.094 13.1 2.5 3.9 7.9 0.2 3.0 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 OEU16658.1 - 0.11 11.2 2.7 3.5 6.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain SRPRB PF09439.10 OEU16658.1 - 0.13 11.7 0.7 0.45 9.9 0.0 2.2 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit DUF3584 PF12128.8 OEU16658.1 - 0.18 9.3 4.6 0.17 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_tran_CTD PF16326.5 OEU16658.1 - 0.36 11.1 5.2 1.2 9.4 5.2 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain Fasciclin PF02469.22 OEU16659.1 - 5e-90 298.3 0.0 3.5e-18 66.0 0.0 6.8 6 1 0 6 6 6 6 Fasciclin domain Aa_trans PF01490.18 OEU16660.1 - 5.2e-42 144.0 3.7 1.2e-41 142.8 3.7 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PAP_fibrillin PF04755.12 OEU16661.1 - 2.9e-18 66.5 0.2 1.2e-17 64.5 0.2 2.0 1 1 0 1 1 1 1 PAP_fibrillin Ank_2 PF12796.7 OEU16662.1 - 4.7e-12 46.3 0.0 2.1e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU16662.1 - 5.3e-11 42.8 0.0 6.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU16662.1 - 1.1e-09 38.3 0.0 3.8e-09 36.6 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU16662.1 - 1.3e-08 34.9 0.1 2.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OEU16662.1 - 2.1e-07 30.7 0.0 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OEU16663.1 - 3.5e-15 55.9 1.2 2.1e-11 43.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU16663.1 - 9.3e-13 48.4 0.3 5.2e-07 30.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU16663.1 - 1.1e-11 45.2 0.3 9.8e-10 38.9 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU16663.1 - 8.8e-09 34.9 0.2 2e-06 27.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU16663.1 - 1.1e-08 35.1 0.1 1.7e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat ADK PF00406.22 OEU16664.1 - 1.2e-34 119.6 0.0 1.4e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU16664.1 - 2e-21 76.8 0.1 2.7e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU16664.1 - 5.7e-12 46.3 0.1 2.5e-11 44.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU16664.1 - 1.8e-09 37.9 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 OEU16664.1 - 0.00073 19.4 0.1 0.073 12.9 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 OEU16664.1 - 0.0019 17.9 0.1 0.14 11.8 0.0 2.1 1 1 1 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 OEU16664.1 - 0.029 13.7 0.1 0.032 13.5 0.1 1.4 1 1 0 1 1 1 0 Zeta toxin CobU PF02283.16 OEU16664.1 - 0.094 12.3 0.2 0.59 9.7 0.0 2.1 2 1 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PPR_2 PF13041.6 OEU16665.1 - 8.5e-10 38.7 0.0 0.83 9.9 0.0 7.9 7 0 0 7 7 7 1 PPR repeat family PPR_1 PF12854.7 OEU16665.1 - 4.3e-06 26.3 5.9 6.7 6.5 0.1 6.3 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.6 OEU16665.1 - 0.0002 21.4 0.8 14 5.8 0.0 5.3 5 0 0 5 5 5 1 Pentatricopeptide repeat domain Mit_KHE1 PF10173.9 OEU16665.1 - 1.4 9.0 5.1 0.8 9.8 1.4 2.2 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related SUIM_assoc PF16619.5 OEU16665.1 - 6 7.0 9.8 0.9 9.7 5.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SNF5 PF04855.12 OEU16666.1 - 7.3e-08 32.5 1.8 3.4e-07 30.3 1.8 1.8 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Arrestin_C PF02752.22 OEU16667.1 - 9.4e-14 52.0 3.3 5.2e-13 49.6 1.2 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OEU16667.1 - 1.3e-07 31.8 0.4 3.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 OEU16667.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like Spo0M PF07070.11 OEU16667.1 - 0.12 11.9 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 SpoOM protein AFG1_ATPase PF03969.16 OEU16668.1 - 4.3e-70 236.4 0.0 9.4e-67 225.4 0.0 2.8 2 1 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 OEU16668.1 - 0.0001 22.2 0.5 0.49 10.2 0.0 3.1 2 1 1 3 3 3 2 Bacterial dnaA protein AAA_16 PF13191.6 OEU16668.1 - 0.0073 16.7 0.2 0.053 13.9 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OEU16668.1 - 0.0098 16.2 0.3 0.056 13.7 0.3 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OEU16668.1 - 0.011 15.5 0.0 1.7 8.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 OEU16668.1 - 0.078 13.4 0.1 0.59 10.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OEU16668.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OEU16668.1 - 0.087 13.2 0.0 1.5 9.3 0.0 2.7 2 1 1 3 3 3 0 RNA helicase CP12 PF02672.15 OEU16670.1 - 5.4e-08 33.5 3.6 0.00049 20.8 0.1 2.8 3 0 0 3 3 3 2 CP12 domain RMI1_N PF08585.12 OEU16671.1 - 9.5e-20 71.3 14.3 1.2e-19 70.9 1.8 3.5 2 1 0 2 2 2 1 RecQ mediated genome instability protein TFIIA PF03153.13 OEU16671.1 - 0.15 12.0 25.6 0.03 14.3 22.2 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 OEU16671.1 - 0.49 9.2 6.0 0.7 8.7 6.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOG2 PF10428.9 OEU16671.1 - 0.68 9.1 30.7 1.4 8.0 30.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Dpy-30 PF05186.13 OEU16672.1 - 1.8e-18 65.9 0.2 2.5e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF5586 PF17824.1 OEU16672.1 - 0.23 10.5 0.6 0.24 10.5 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5586) DUF3891 PF13030.6 OEU16673.1 - 0.013 15.3 0.5 0.015 15.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) EF-hand_1 PF00036.32 OEU16674.1 - 2.6e-41 136.1 14.6 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OEU16674.1 - 1.3e-34 118.4 3.5 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU16674.1 - 1.8e-30 102.3 8.0 1.3e-09 37.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OEU16674.1 - 2.3e-30 104.2 12.9 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OEU16674.1 - 1.9e-27 93.5 10.4 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OEU16674.1 - 7.2e-15 55.1 0.2 7.3e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OEU16674.1 - 1.9e-09 37.4 0.7 0.00013 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OEU16674.1 - 1.3e-07 31.9 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OEU16674.1 - 3.1e-06 28.0 0.0 0.00016 22.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OEU16674.1 - 0.00013 21.9 2.0 0.28 11.3 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 OEU16674.1 - 0.00013 21.9 1.6 0.00037 20.5 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OEU16674.1 - 0.00055 20.1 2.3 0.044 14.0 0.3 2.8 1 1 3 4 4 4 1 Dockerin type I domain DUF3349 PF11829.8 OEU16674.1 - 0.0022 18.7 0.3 1.4 9.7 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 OEU16674.1 - 0.0029 17.5 0.9 0.21 11.5 0.3 3.2 1 1 1 2 2 2 1 Caleosin related protein TerB PF05099.13 OEU16674.1 - 0.0036 17.3 0.2 1.3 9.0 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 OEU16674.1 - 0.011 14.3 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF4497 PF14924.6 OEU16674.1 - 0.013 15.9 0.0 6.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 OEU16674.1 - 0.02 15.2 0.7 0.73 10.2 0.1 2.5 3 0 0 3 3 2 0 RNA polymerase Rpb4 SurA_N_2 PF13623.6 OEU16674.1 - 0.032 14.1 0.5 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 OEU16674.1 - 0.034 14.3 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF853 PF05872.12 OEU16674.1 - 0.037 12.6 0.1 0.62 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 OEU16674.1 - 0.076 13.3 0.1 11 6.3 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein FGAR-AT_linker PF18072.1 OEU16674.1 - 0.093 13.3 0.3 4.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain SapB_1 PF05184.15 OEU16674.1 - 0.18 11.9 2.4 22 5.2 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 PGM_PMM_I PF02878.16 OEU16675.1 - 9.5e-29 99.9 0.0 4.5e-28 97.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OEU16675.1 - 8.7e-21 74.5 0.1 2.5e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OEU16675.1 - 5.7e-13 49.1 0.0 1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OEU16675.1 - 2.6e-05 24.3 0.0 5.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GP3 PF03076.14 OEU16675.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus GP3 EF-hand_1 PF00036.32 OEU16676.1 - 9e-35 115.6 21.2 2.3e-09 36.1 1.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OEU16676.1 - 1.1e-32 112.3 7.0 1.4e-17 63.8 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU16676.1 - 3.3e-28 95.2 10.7 2.3e-08 33.3 0.2 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OEU16676.1 - 1.3e-23 82.5 14.8 2.7e-15 55.9 1.2 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OEU16676.1 - 5.2e-22 76.3 17.8 6.2e-07 28.6 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OEU16676.1 - 1.1e-16 60.8 0.3 4.2e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU16676.1 - 2.8e-08 34.0 0.8 0.0063 16.8 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OEU16676.1 - 3.3e-08 33.4 0.5 0.0064 16.5 0.0 2.5 3 0 0 3 3 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OEU16676.1 - 2.4e-06 28.4 0.0 0.0014 19.5 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OEU16676.1 - 1e-05 25.6 4.8 0.066 13.4 0.5 3.4 1 1 3 4 4 4 3 Dockerin type I domain EF-hand_4 PF12763.7 OEU16676.1 - 1.6e-05 24.8 9.6 0.22 11.5 0.4 3.5 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 OEU16676.1 - 4.3e-05 23.7 0.5 0.0048 17.1 0.1 2.7 1 1 2 3 3 3 1 p25-alpha DUF3349 PF11829.8 OEU16676.1 - 0.00024 21.8 0.4 0.72 10.7 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3349) FGAR-AT_linker PF18072.1 OEU16676.1 - 0.00057 20.4 0.5 0.26 11.9 0.1 2.9 2 1 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain TerB PF05099.13 OEU16676.1 - 0.003 17.5 1.4 0.039 13.9 0.0 2.5 1 1 2 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.13 OEU16676.1 - 0.0042 17.0 0.1 0.3 11.0 0.0 2.8 1 1 3 4 4 4 1 Caleosin related protein DUF4191 PF13829.6 OEU16676.1 - 0.02 14.3 0.0 4.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SurA_N_2 PF13623.6 OEU16676.1 - 0.028 14.3 1.3 2.9 7.8 0.2 2.6 2 1 0 2 2 2 0 SurA N-terminal domain UBA_6 PF18039.1 OEU16676.1 - 0.036 14.0 0.1 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain DUF533 PF04391.12 OEU16676.1 - 0.037 13.6 1.9 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) GlutR_dimer PF00745.20 OEU16676.1 - 0.05 14.0 1.6 1.9 9.0 0.4 2.4 1 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain SRP54_N PF02881.19 OEU16676.1 - 0.058 13.6 3.0 0.91 9.8 0.2 2.8 2 1 0 2 2 2 0 SRP54-type protein, helical bundle domain ExbD PF02472.16 OEU16676.1 - 0.062 13.5 0.1 7 6.8 0.0 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Bile_Hydr_Trans PF04775.14 OEU16676.1 - 0.063 13.3 0.0 5.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Cadherin_C PF01049.17 OEU16676.1 - 0.075 13.4 0.2 0.088 13.1 0.2 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region VbhA PF18495.1 OEU16676.1 - 0.095 12.6 0.2 79 3.2 0.0 4.0 4 0 0 4 4 4 0 Antitoxin VbhA SurA_N_3 PF13624.6 OEU16676.1 - 0.11 12.3 0.8 2 8.2 0.2 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF4479 PF14794.6 OEU16676.1 - 0.12 12.2 0.7 26 4.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4479) FG-GAP PF01839.23 OEU16676.1 - 0.97 9.6 3.4 29 4.9 0.1 2.5 2 0 0 2 2 2 0 FG-GAP repeat DUF572 PF04502.13 OEU16677.1 - 3.9e-27 95.8 15.2 4.7e-27 95.5 15.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) TPR_19 PF14559.6 OEU16678.1 - 0.002 18.6 0.2 0.02 15.4 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16678.1 - 0.0025 18.1 0.2 4.2 8.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Chorion_2 PF03964.15 OEU16678.1 - 0.0064 17.3 4.7 0.022 15.6 4.7 2.0 1 0 0 1 1 1 1 Chorion family 2 PyrI PF01948.18 OEU16678.1 - 0.0089 16.3 0.4 0.057 13.7 0.1 2.4 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain TPR_2 PF07719.17 OEU16678.1 - 0.019 15.0 0.2 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16678.1 - 0.023 14.5 1.0 6.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OEU16678.1 - 0.032 13.9 0.6 6.1 6.6 0.1 2.5 2 0 0 2 2 2 0 TPR repeat CDC45 PF02724.14 OEU16678.1 - 0.046 12.0 24.4 0.074 11.3 24.4 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_14 PF13428.6 OEU16678.1 - 0.12 13.3 0.0 7.6 7.7 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat ThiF PF00899.21 OEU16679.1 - 1.5e-30 106.4 0.1 2.4e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 OEU16679.1 - 9.4e-05 22.1 0.1 0.00021 21.0 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OEU16679.1 - 0.0029 17.8 0.3 0.71 10.1 0.0 2.6 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OEU16679.1 - 0.0074 15.9 0.4 0.023 14.4 0.4 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 OEU16679.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain LTXXQ PF07813.12 OEU16679.1 - 0.11 13.2 2.4 0.25 12.1 2.4 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein 3HCDH_N PF02737.18 OEU16679.1 - 0.29 11.0 1.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1581 PF07619.11 OEU16680.1 - 0.045 13.9 0.2 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) GIIM PF08388.11 OEU16680.1 - 0.68 10.0 1.8 23 5.1 0.2 2.4 2 0 0 2 2 2 0 Group II intron, maturase-specific domain CedA PF10729.9 OEU16681.1 - 0.0045 16.8 0.7 30 4.6 0.0 4.8 2 1 3 5 5 5 3 Cell division activator CedA SR-25 PF10500.9 OEU16682.1 - 0.068 12.8 21.4 0.16 11.6 21.4 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Endotoxin_N PF03945.14 OEU16682.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Plasmid_parti PF01672.16 OEU16684.1 - 1 10.0 6.2 2.5 8.8 0.8 2.3 1 1 1 2 2 2 0 Putative plasmid partition protein MRP-L27 PF09809.9 OEU16686.1 - 5.3e-13 48.8 0.1 5.9e-13 48.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF2183 PF09949.9 OEU16687.1 - 4.4e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Beta_helix PF13229.6 OEU16688.1 - 0.029 14.2 2.0 0.11 12.3 2.0 2.0 1 1 0 1 1 1 0 Right handed beta helix region Peptidase_M90 PF06167.12 OEU16690.1 - 0.056 13.0 0.5 0.47 10.0 0.1 2.2 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 RNaseH_C PF09293.10 OEU16690.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 T4 RNase H, C terminal FBPase PF00316.20 OEU16691.1 - 2.3e-40 138.1 0.0 3.4e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CPBP PF02517.16 OEU16692.1 - 3.5e-18 65.7 3.1 4e-18 65.6 3.1 1.0 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease PT PF04886.12 OEU16695.1 - 3.2e-08 33.0 16.7 0.023 14.2 16.7 2.5 1 1 0 1 1 1 1 PT repeat DUF285 PF03382.14 OEU16696.1 - 6.9e-57 190.4 36.8 1.3e-29 102.4 15.3 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Chordopox_E11 PF06138.12 OEU16696.1 - 0.0097 16.2 1.1 0.45 10.8 0.1 2.8 1 1 2 3 3 3 2 Chordopoxvirus E11 protein Hemocyanin_N PF03722.14 OEU16696.1 - 0.026 15.0 1.2 0.071 13.6 1.0 1.8 1 1 1 2 2 2 0 Hemocyanin, all-alpha domain Neurensin PF14927.6 OEU16696.1 - 0.037 13.7 0.1 1.9 8.2 0.0 2.9 1 1 2 3 3 3 0 Neurensin CBM64 PF18666.1 OEU16696.1 - 1.3 9.2 11.9 25 5.0 0.2 4.3 1 1 3 4 4 4 0 Carbohydrate-binding module 64 DUF2431 PF10354.9 OEU16697.1 - 1.4e-11 45.0 0.0 2.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zinc_ribbon_9 PF14369.6 OEU16697.1 - 0.0033 17.7 11.2 0.027 14.7 0.0 4.1 4 0 0 4 4 4 2 zinc-ribbon zf-Di19 PF05605.12 OEU16697.1 - 0.0036 17.6 17.9 0.024 14.9 1.7 5.3 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 OEU16697.1 - 0.013 15.4 0.5 7.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_UBZ PF18439.1 OEU16697.1 - 0.061 12.9 10.4 6.5 6.4 0.6 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 OEU16697.1 - 0.086 12.3 9.0 0.22 11.0 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_3rep PF18868.1 OEU16697.1 - 0.1 13.3 9.5 2.2 9.0 1.5 3.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats FYDLN_acid PF09538.10 OEU16697.1 - 0.17 12.6 12.2 2.9e+02 2.2 12.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-FPG_IleRS PF06827.14 OEU16697.1 - 0.44 10.5 0.1 0.44 10.5 0.1 3.2 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Sgf11 PF08209.11 OEU16697.1 - 0.76 9.4 0.0 0.76 9.4 0.0 3.8 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-C2H2_12 PF18658.1 OEU16697.1 - 2.5 7.7 6.0 0.74 9.4 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type UBZ_FAAP20 PF15750.5 OEU16697.1 - 3.7 7.6 9.3 5 7.1 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger HMG_box PF00505.19 OEU16698.1 - 6.5e-34 116.2 14.7 2.1e-21 76.1 1.2 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU16698.1 - 3.3e-22 78.8 15.2 8.3e-12 45.5 1.0 2.9 3 0 0 3 3 3 2 HMG-box domain Carbpep_Y_N PF05388.11 OEU16698.1 - 0.018 15.5 0.1 0.041 14.4 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Sigma70_r4 PF04545.16 OEU16699.1 - 1e-13 50.5 0.6 2.5e-11 42.9 0.2 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 OEU16699.1 - 5.8e-12 45.2 0.0 1.7e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 OEU16699.1 - 0.0003 20.8 0.0 0.0082 16.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-70 region 3 MarR_2 PF12802.7 OEU16699.1 - 0.011 15.5 0.8 2.4 8.1 0.7 3.1 2 1 1 3 3 3 0 MarR family Sigma70_r4_2 PF08281.12 OEU16699.1 - 0.065 12.9 2.2 9.5 6.0 1.2 3.3 2 1 0 2 2 2 0 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 OEU16699.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF4160 PF13711.6 OEU16699.1 - 0.23 11.8 1.0 1.8 8.9 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4160) IF2_N PF04760.15 OEU16699.1 - 0.35 10.7 2.4 1.8 8.5 0.1 3.2 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region XPG_I PF00867.18 OEU16701.1 - 2.3e-19 69.5 0.3 7.5e-19 67.9 0.3 2.0 1 0 0 1 1 1 1 XPG I-region Chromo_2 PF18704.1 OEU16701.1 - 5.3e-09 36.2 0.1 1.7e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 XPG_N PF00752.17 OEU16701.1 - 1.5e-06 28.6 0.0 5.6e-06 26.8 0.0 1.9 1 1 0 2 2 2 1 XPG N-terminal domain zinc_ribbon_12 PF11331.8 OEU16701.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OEU16701.1 - 1.3 9.0 6.1 3.7 7.5 6.1 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain EPL1 PF10513.9 OEU16702.1 - 5.7e-07 30.0 1.2 5.7e-07 30.0 1.2 2.0 2 1 0 2 2 2 1 Enhancer of polycomb-like PUF PF00806.19 OEU16703.1 - 1.8e-32 109.2 0.8 2.2e-07 30.2 0.0 5.4 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat FliG_C PF01706.16 OEU16703.1 - 0.0043 17.2 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 FliG C-terminal domain Neuropep_like PF15161.6 OEU16703.1 - 0.016 14.8 0.1 0.044 13.4 0.1 1.7 1 0 0 1 1 1 0 Neuropeptide-like FA_FANCE PF11510.8 OEU16703.1 - 0.027 13.8 0.2 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE Skp1 PF01466.19 OEU16705.1 - 2.5e-19 69.1 0.9 4.3e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OEU16705.1 - 1.8e-14 53.6 3.4 4.8e-14 52.3 3.4 1.8 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain IFT46_B_C PF12317.8 OEU16705.1 - 0.00037 20.3 0.8 0.00046 20.0 0.8 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal RasGEF PF00617.19 OEU16705.1 - 0.011 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 RasGEF domain CENP-B_dimeris PF09026.10 OEU16705.1 - 4.8 7.6 9.6 0.41 11.1 3.8 2.1 2 1 0 2 2 2 0 Centromere protein B dimerisation domain AMP-binding PF00501.28 OEU16707.1 - 5.8e-92 308.5 0.1 7.3e-92 308.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OEU16707.1 - 0.0019 19.2 0.0 0.0052 17.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PSP94 PF05825.11 OEU16707.1 - 0.12 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) SGL PF08450.12 OEU16708.1 - 6.7e-48 163.4 0.1 8.3e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region EGF_3 PF12947.7 OEU16709.1 - 8.5e-09 35.5 47.8 0.00022 21.3 3.3 5.9 5 0 0 5 5 5 3 EGF domain EGF_CA PF07645.15 OEU16709.1 - 2.6e-07 30.7 18.9 3.5e-07 30.3 3.1 7.6 7 2 0 7 7 7 2 Calcium-binding EGF domain hEGF PF12661.7 OEU16709.1 - 5.4e-06 26.8 30.7 0.04 14.6 1.6 6.2 5 0 0 5 5 5 4 Human growth factor-like EGF DUF5011 PF16403.5 OEU16709.1 - 1.8e-05 24.7 2.1 0.21 11.7 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF5011) cEGF PF12662.7 OEU16709.1 - 0.012 15.5 1.1 0.012 15.5 1.1 6.6 7 0 0 7 7 7 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 OEU16709.1 - 0.022 15.1 35.0 0.16 12.3 2.4 6.0 4 1 1 5 5 5 0 Pvs28 EGF domain FXa_inhibition PF14670.6 OEU16709.1 - 0.18 12.1 46.1 0.09 13.1 1.5 5.7 5 0 0 5 5 5 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 OEU16709.1 - 1.3 9.4 42.7 0.064 13.6 1.8 6.9 5 2 1 6 6 6 0 EGF-like domain PT PF04886.12 OEU16710.1 - 0.00049 19.6 22.4 0.33 10.5 9.8 2.5 1 1 1 2 2 2 2 PT repeat Nop14 PF04147.12 OEU16710.1 - 0.017 13.4 0.1 0.021 13.0 0.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OEU16710.1 - 0.92 7.7 5.9 1.3 7.2 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 OEU16710.1 - 6.4 7.2 12.3 52 4.3 10.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-TRAF PF02176.18 OEU16711.1 - 0.023 15.4 2.4 0.033 14.9 0.2 2.3 3 0 0 3 3 3 0 TRAF-type zinc finger Spidroin_MaSp PF11260.8 OEU16711.1 - 0.24 11.7 0.0 0.38 11.1 0.0 1.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 MgtC PF02308.16 OEU16714.1 - 1.1e-29 103.3 8.9 1.5e-29 102.9 8.9 1.2 1 0 0 1 1 1 1 MgtC family CaMKII_AD PF08332.10 OEU16715.1 - 0.016 15.4 6.0 2.9 8.0 1.7 3.3 1 1 1 2 2 2 0 Calcium/calmodulin dependent protein kinase II association domain Methyltransf_12 PF08242.12 OEU16716.1 - 2.8e-05 24.8 0.1 0.049 14.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16716.1 - 3.3e-05 24.5 0.0 0.00016 22.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16716.1 - 0.00023 21.7 0.0 0.032 14.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 OEU16716.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain ApbA_C PF08546.11 OEU16716.1 - 0.23 11.7 0.0 0.53 10.5 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal SET PF00856.28 OEU16718.1 - 7.4e-11 42.7 0.0 0.0013 19.1 0.0 3.5 2 1 0 2 2 2 2 SET domain WD40 PF00400.32 OEU16719.1 - 7.7e-30 102.5 20.6 0.00044 21.0 0.7 9.6 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU16719.1 - 3.8e-11 43.2 2.4 0.0073 16.6 0.1 6.6 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OEU16719.1 - 1.7e-06 27.6 0.9 0.01 15.2 0.1 3.3 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 OEU16719.1 - 0.012 14.6 0.5 0.096 11.6 0.1 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OEU16719.1 - 0.17 12.4 0.7 24 5.6 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Cupin_4 PF08007.12 OEU16720.1 - 2.9e-38 132.1 0.1 4e-38 131.7 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU16720.1 - 8.9e-08 32.1 0.0 1.8e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain HrpB1_HrpK PF09613.10 OEU16720.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) HTH_22 PF13309.6 OEU16720.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain Myb_DNA-binding PF00249.31 OEU16721.1 - 8.6e-50 166.7 17.2 6.1e-18 64.8 1.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU16721.1 - 3.1e-37 126.6 11.0 6.6e-18 64.7 0.7 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OEU16721.1 - 1.4e-07 31.5 0.1 0.2 11.7 0.0 3.1 1 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OEU16721.1 - 3.7e-06 26.7 0.3 0.069 13.0 0.0 3.0 1 1 2 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 OEU16721.1 - 0.057 13.5 5.6 1.9 8.6 3.1 3.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sigma70_r4_2 PF08281.12 OEU16721.1 - 0.1 12.3 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 EMP24_GP25L PF01105.24 OEU16722.1 - 2.6e-18 66.6 0.2 3.7e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DDE_Tnp_1_7 PF13843.6 OEU16725.1 - 9e-17 61.4 0.4 2.9e-16 59.7 0.3 1.8 1 1 0 1 1 1 1 Transposase IS4 Cation_efflux PF01545.21 OEU16726.1 - 1.3e-46 158.8 5.3 1.6e-46 158.5 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family TFIIE-A_C PF11521.8 OEU16728.1 - 0.0035 17.6 0.8 0.0035 17.6 0.8 2.3 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha T4_Rnl2_C PF18043.1 OEU16729.1 - 0.22 11.7 2.9 9.9 6.4 0.0 2.8 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal MGDG_synth PF06925.11 OEU16730.1 - 2e-21 76.9 0.0 3e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 OEU16730.1 - 6.2e-13 49.1 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 OEU16730.1 - 6.5e-07 29.9 0.3 2.5e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OEU16730.1 - 8.2e-07 28.7 0.0 2.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 OEU16730.1 - 0.0012 17.7 0.0 0.0029 16.5 0.0 1.7 2 1 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Trp_syntA PF00290.20 OEU16733.1 - 1.7e-81 272.9 0.2 2.7e-81 272.2 0.2 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 OEU16733.1 - 5.2e-43 147.5 1.2 5.2e-43 147.5 1.2 2.3 3 0 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 OEU16733.1 - 5.3e-05 22.8 0.2 0.0008 18.9 0.0 2.7 3 0 0 3 3 3 1 Histidine biosynthesis protein PcrB PF01884.17 OEU16733.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 PcrB family BtpA PF03437.15 OEU16733.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 BtpA family SGS PF05002.15 OEU16734.1 - 0.045 13.9 0.3 0.058 13.5 0.3 1.2 1 0 0 1 1 1 0 SGS domain DUF2670 PF10875.8 OEU16734.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) TMPIT PF07851.13 OEU16735.1 - 0.032 13.5 0.6 0.037 13.3 0.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_L29e PF01779.17 OEU16735.1 - 0.058 13.7 0.3 0.11 12.9 0.3 1.4 1 0 0 1 1 1 0 Ribosomal L29e protein family DUF1514 PF07438.11 OEU16735.1 - 0.21 11.5 2.6 0.56 10.1 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1514) Sar8_2 PF03058.14 OEU16735.1 - 0.4 11.2 1.5 0.7 10.5 1.1 1.8 1 1 1 2 2 2 0 Sar8.2 family DUF1189 PF06691.11 OEU16735.1 - 0.7 9.4 3.8 0.27 10.7 1.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) Ion_trans PF00520.31 OEU16737.1 - 3e-20 72.5 21.8 9.1e-20 70.9 22.0 1.7 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OEU16737.1 - 1.3e-09 37.9 18.9 4.7e-09 36.1 13.1 3.4 2 1 0 2 2 2 1 Ion channel Mito_carr PF00153.27 OEU16739.1 - 1.3e-64 214.1 1.4 4.1e-22 77.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OEU16739.1 - 0.006 15.8 0.2 6 5.9 0.0 3.6 3 1 1 4 4 4 2 Gammaproteobacterial serine protease EutK_C PF16365.5 OEU16739.1 - 0.019 15.0 0.2 0.12 12.4 0.0 2.3 3 0 0 3 3 3 0 Ethanolamine utilization protein EutK C-terminus Fascin PF06268.13 OEU16740.1 - 0.054 13.7 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Fascin domain DnaJ PF00226.31 OEU16741.1 - 5.1e-18 65.0 0.9 5.1e-18 65.0 0.9 1.6 2 0 0 2 2 2 1 DnaJ domain DUF3429 PF11911.8 OEU16741.1 - 0.035 14.4 0.6 3.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) DUF3270 PF11674.8 OEU16741.1 - 0.096 12.9 1.3 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) tRNA-synt_2 PF00152.20 OEU16742.1 - 1e-64 218.6 0.0 1.4e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OEU16742.1 - 3.8e-16 58.8 0.4 7.7e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CS PF04969.16 OEU16743.1 - 4.8e-18 65.9 1.3 7.2e-18 65.4 1.3 1.3 1 0 0 1 1 1 1 CS domain Osteopontin PF00865.18 OEU16743.1 - 0.00034 20.2 3.9 0.00049 19.7 3.9 1.2 1 0 0 1 1 1 1 Osteopontin Zn_ribbon_17 PF17120.5 OEU16744.1 - 7e-10 38.4 6.7 7e-10 38.4 6.7 2.7 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type Cript PF10235.9 OEU16744.1 - 0.036 14.6 0.4 0.036 14.6 0.4 3.0 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT zinc_ribbon_16 PF17034.5 OEU16744.1 - 0.072 13.3 9.7 1.4 9.1 9.7 2.8 1 1 0 1 1 1 0 Zinc-ribbon like family PT PF04886.12 OEU16745.1 - 1.3e-13 50.2 43.4 1.2e-07 31.2 9.0 3.5 1 1 2 3 3 3 3 PT repeat Rick_17kDa_Anti PF05433.15 OEU16746.1 - 1.6e-07 31.1 57.5 0.053 13.4 8.6 8.0 3 2 3 7 7 7 6 Glycine zipper 2TM domain Yae1_N PF09811.9 OEU16746.1 - 4.7e-07 29.4 39.2 6.5 6.5 2.6 11.7 2 2 3 5 5 5 3 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU16746.1 - 0.00056 19.9 53.2 0.1 12.6 6.8 6.8 1 1 3 4 4 4 2 Glycine zipper MccV PF17508.2 OEU16746.1 - 2.1 8.9 19.9 41 4.8 0.3 5.6 1 1 3 4 4 4 0 Microcin V bacteriocin Gly-zipper_YMGG PF13441.6 OEU16746.1 - 2.4 8.0 44.8 0.08 12.7 3.0 6.6 1 1 1 3 3 3 0 YMGG-like Gly-zipper Nucleoporin_FG2 PF15967.5 OEU16746.1 - 4.2 5.8 30.8 2.7 6.4 0.8 6.0 1 1 5 6 6 6 0 Nucleoporin FG repeated region PT PF04886.12 OEU16747.1 - 5.6e-09 35.4 60.3 0.064 12.8 9.6 5.2 1 1 1 2 2 2 1 PT repeat MISS PF15822.5 OEU16747.1 - 0.68 9.7 49.8 2 8.2 21.6 2.0 1 1 1 2 2 2 0 MAPK-interacting and spindle-stabilising protein-like PT PF04886.12 OEU16748.1 - 0.00064 19.2 113.4 1.8e+04 -68.9 113.4 5.1 1 1 0 1 1 1 0 PT repeat TSGP1 PF07771.11 OEU16749.1 - 3.8 7.7 6.9 0.77 9.9 2.1 2.4 2 0 0 2 2 2 0 Tick salivary peptide group 1 DnaJ PF00226.31 OEU16753.1 - 1.6e-17 63.4 2.4 6.3e-17 61.5 2.4 2.1 1 1 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 OEU16753.1 - 0.043 13.6 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACR_tran PF00873.19 OEU16753.1 - 0.11 10.1 5.2 0.16 9.6 5.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PIGA PF08288.12 OEU16754.1 - 2.4e-36 124.2 0.1 6.2e-36 122.9 0.1 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OEU16754.1 - 1.8e-30 106.1 0.2 2.8e-30 105.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OEU16754.1 - 3e-29 101.8 0.0 5.7e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU16754.1 - 1.5e-23 83.7 0.5 1.9e-22 80.1 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OEU16754.1 - 1.9e-15 57.7 0.0 3.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OEU16754.1 - 4.6e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OEU16754.1 - 0.006 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 OEU16754.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Starch synthase catalytic domain Ank_2 PF12796.7 OEU16755.1 - 9.9e-12 45.3 0.1 3e-09 37.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU16755.1 - 1.4e-08 34.7 0.1 0.023 15.1 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OEU16755.1 - 9.1e-07 29.0 0.0 0.0012 19.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU16755.1 - 2.1e-06 28.2 0.0 0.00014 22.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU16755.1 - 2.4e-05 24.4 0.0 0.078 13.6 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat RPAP1_N PF08621.10 OEU16756.1 - 5.3e-08 32.5 3.9 1.8e-07 30.8 3.9 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal Metallophos_2 PF12850.7 OEU16757.1 - 1.3e-20 74.3 0.1 1.6e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OEU16757.1 - 0.00084 19.9 0.0 0.2 12.1 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase ANAPC5 PF12862.7 OEU16758.1 - 4.8e-21 74.6 2.0 4.8e-21 74.6 2.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_16 PF13432.6 OEU16758.1 - 7e-06 26.6 7.3 0.83 10.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU16758.1 - 1.1e-05 25.6 7.5 0.0016 18.7 0.2 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU16758.1 - 0.045 13.8 1.2 12 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16758.1 - 0.12 12.3 1.4 13 5.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU16758.1 - 0.27 12.1 5.5 1.8 9.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.23 OEU16759.1 - 4.1e-17 62.1 0.9 5.9e-17 61.6 0.4 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU16759.1 - 1.6e-05 25.0 1.2 3.9e-05 23.7 0.1 2.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain DUF3439 PF11921.8 OEU16760.1 - 0.32 11.0 11.5 0.77 9.7 7.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Methyltransf_12 PF08242.12 OEU16760.1 - 0.38 11.5 0.1 0.38 11.5 0.1 2.4 2 1 1 3 3 3 0 Methyltransferase domain Abhydrolase_6 PF12697.7 OEU16761.1 - 9.4e-06 26.4 0.0 2.3e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OEU16761.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 OEU16761.1 - 0.0036 16.9 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OEU16761.1 - 0.024 14.5 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 OEU16761.1 - 0.027 14.1 0.0 0.25 10.9 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold RAMP4 PF06624.12 OEU16761.1 - 0.091 12.8 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 FSH1 PF03959.13 OEU16761.1 - 0.15 11.7 0.1 0.29 10.7 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 OEU16761.1 - 0.16 10.6 0.0 0.72 8.5 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) SnoaL_3 PF13474.6 OEU16763.1 - 2.5e-17 63.2 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OEU16763.1 - 1.4e-08 35.1 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OEU16763.1 - 4.7e-05 24.0 0.0 0.00012 22.6 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 OEU16763.1 - 0.0011 19.1 0.2 0.029 14.5 0.2 2.0 1 1 0 1 1 1 1 SnoaL-like domain Maf PF02545.14 OEU16764.1 - 8.2e-51 172.2 0.0 9.3e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ketoacyl-synt PF00109.26 OEU16766.1 - 1.7e-12 47.5 2.9 7.1e-09 35.6 0.8 2.8 2 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OEU16766.1 - 1.4e-08 34.5 0.5 5.4e-07 29.4 0.4 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 OEU16767.1 - 2.4e-72 242.5 0.3 3.5e-72 241.9 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 OEU16767.1 - 2.4e-65 221.0 0.9 2.7e-65 220.8 0.1 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF2722 PF10846.8 OEU16767.1 - 0.0041 16.1 2.1 0.0053 15.8 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) ACP_syn_III_C PF08541.10 OEU16767.1 - 0.08 13.1 0.2 0.3 11.3 0.2 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Pal1 PF08316.11 OEU16767.1 - 0.16 12.7 3.7 0.42 11.4 3.7 1.6 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4834 PF16118.5 OEU16767.1 - 0.66 11.0 4.6 1.7 9.6 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 OEU16767.1 - 1.1 8.8 14.0 0.89 9.1 12.5 1.6 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 OEU16767.1 - 7.2 5.7 13.4 11 5.1 13.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mpv17_PMP22 PF04117.12 OEU16769.1 - 2.8e-12 46.7 0.9 2.8e-12 46.7 0.9 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family AAA PF00004.29 OEU16770.1 - 1.7e-40 138.5 0.0 4.6e-40 137.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 OEU16770.1 - 1.4e-19 69.9 0.7 3e-19 68.9 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 OEU16770.1 - 4.5e-15 55.4 0.0 1.6e-14 53.6 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 OEU16770.1 - 6.6e-06 25.8 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OEU16770.1 - 1.2e-05 25.6 0.3 0.0055 17.0 0.1 3.4 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 OEU16770.1 - 3.3e-05 23.7 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OEU16770.1 - 5.9e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 OEU16770.1 - 7.1e-05 22.6 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OEU16770.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 OEU16770.1 - 0.00017 20.8 0.0 0.00032 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OEU16770.1 - 0.00044 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU16770.1 - 0.0005 20.1 0.0 0.0024 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU16770.1 - 0.0014 19.1 0.1 0.0057 17.1 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 OEU16770.1 - 0.0024 18.1 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU16770.1 - 0.004 17.7 0.0 0.013 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OEU16770.1 - 0.0069 16.8 0.0 0.048 14.0 0.0 2.4 2 1 0 2 2 2 1 RNA helicase TIP49 PF06068.13 OEU16770.1 - 0.0095 15.2 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 OEU16770.1 - 0.018 15.5 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OEU16770.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TF_Zn_Ribbon PF08271.12 OEU16770.1 - 0.042 13.4 0.7 0.12 12.0 0.7 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Sigma54_activat PF00158.26 OEU16770.1 - 0.054 13.2 0.0 0.41 10.3 0.0 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 OEU16770.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 OEU16770.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OEU16770.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 OEU16770.1 - 0.08 12.5 0.2 1.3 8.6 0.1 2.2 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU16770.1 - 0.12 12.3 0.0 2.2 8.2 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 OEU16770.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 OEU16770.1 - 0.2 11.5 0.0 0.94 9.3 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein Acetyltransf_7 PF13508.7 OEU16771.1 - 4e-06 27.2 0.0 7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU16771.1 - 0.005 17.1 0.1 0.0089 16.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CRA PF06589.11 OEU16771.1 - 0.011 15.9 0.9 0.062 13.4 0.9 2.0 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) YlaC PF10777.9 OEU16771.1 - 0.32 10.8 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC CRAL_TRIO PF00650.20 OEU16772.1 - 4.8e-19 68.6 0.0 7.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU16772.1 - 7.5e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ERCC4 PF02732.15 OEU16773.1 - 1.3e-16 61.1 0.2 7.8e-16 58.7 0.0 2.5 2 1 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.6 OEU16773.1 - 0.01 16.4 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain MazG_C PF18722.1 OEU16773.1 - 0.12 11.9 3.0 0.23 11.0 1.3 2.2 2 0 0 2 2 2 0 MazG C-terminal domain RVT_1 PF00078.27 OEU16775.1 - 6.2e-05 22.6 0.0 0.00022 20.8 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU16775.1 - 0.00053 19.6 0.2 0.0012 18.4 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OEU16775.1 - 0.082 13.6 0.9 0.41 11.4 0.9 2.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RNase_PH PF01138.21 OEU16777.1 - 6.7e-11 42.8 0.2 6.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OEU16777.1 - 1.4e-07 31.4 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF5476 PF17570.2 OEU16777.1 - 0.19 12.1 0.1 0.79 10.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5476) polyprenyl_synt PF00348.17 OEU16778.1 - 2.3e-62 210.4 0.1 2.9e-62 210.1 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ArdA PF07275.11 OEU16778.1 - 0.029 15.0 0.0 0.047 14.3 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Mito_carr PF00153.27 OEU16779.1 - 1.7e-14 53.5 0.2 1e-13 51.0 0.2 2.1 1 1 0 1 1 1 1 Mitochondrial carrier protein CwfJ_C_2 PF04676.14 OEU16780.1 - 1.9e-23 83.2 0.1 2.2e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zinc_ribbon_16 PF17034.5 OEU16781.1 - 1.9e-21 76.6 11.0 1.9e-21 76.6 11.0 2.4 2 0 0 2 2 2 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 OEU16781.1 - 0.00029 21.1 0.1 0.03 14.6 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC_CDC26 PF10471.9 OEU16781.1 - 0.011 16.6 12.7 0.045 14.6 12.7 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 RuBisCO_small PF00101.20 OEU16781.1 - 0.012 15.5 0.2 0.07 13.1 0.1 2.3 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain Spt20 PF12090.8 OEU16781.1 - 0.017 14.7 13.4 0.045 13.4 13.4 1.7 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OEU16781.1 - 0.045 13.7 7.5 0.083 12.9 7.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 OEU16781.1 - 0.35 11.5 12.0 1.1 9.9 10.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAP65_ASE1 PF03999.12 OEU16781.1 - 0.95 8.1 5.2 1.4 7.5 5.2 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Roughex PF06020.11 OEU16781.1 - 2 7.4 7.8 4.6 6.2 7.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Activator_LAG-3 PF11498.8 OEU16781.1 - 5 6.0 18.8 7.6 5.4 18.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RasGEF_N PF00618.20 OEU16782.1 - 0.12 12.6 2.4 1.7 8.9 0.2 3.4 2 0 0 2 2 2 0 RasGEF N-terminal motif TPR_14 PF13428.6 OEU16783.1 - 1.5e-05 25.4 0.1 0.012 16.4 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU16783.1 - 7.7e-05 22.1 0.2 0.00031 20.1 0.0 2.1 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 OEU16783.1 - 0.00029 20.7 0.2 0.16 12.2 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16783.1 - 0.0012 18.5 0.8 3.3 7.7 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 OEU16783.1 - 0.0021 18.1 0.3 2.1 8.5 0.0 2.7 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 OEU16783.1 - 0.0025 18.3 0.5 1.1 10.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU16783.1 - 0.0044 17.5 0.9 1.5 9.4 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU16783.1 - 0.0048 17.5 0.8 0.44 11.2 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16783.1 - 0.0076 16.6 4.2 5.6 7.6 0.0 5.0 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU16783.1 - 0.028 14.7 2.5 11 6.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16783.1 - 0.031 14.5 0.7 11 6.6 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU16783.1 - 0.038 14.0 0.4 3.4 7.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat K_channel_TID PF07941.11 OEU16783.1 - 0.087 13.3 0.6 0.087 13.3 0.6 4.7 5 1 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain ANAPC3 PF12895.7 OEU16783.1 - 0.21 11.8 1.6 1.4 9.2 0.1 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 EF-hand_7 PF13499.6 OEU16784.1 - 1.4e-14 54.2 0.4 2.3e-08 34.3 0.1 3.9 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OEU16784.1 - 2.7e-14 51.8 1.2 0.0093 15.8 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OEU16784.1 - 3e-14 51.8 5.5 6.4e-05 22.3 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_1 PF00036.32 OEU16784.1 - 2.6e-13 48.5 1.7 0.0075 15.8 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OEU16784.1 - 2.5e-05 24.0 2.2 0.91 9.4 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU16784.1 - 0.00067 20.0 0.3 0.046 14.1 0.0 3.4 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Thymidylate_kin PF02223.17 OEU16785.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase DUF3522 PF12036.8 OEU16785.1 - 0.34 11.2 11.4 0.55 10.5 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) Ceramidase PF05875.12 OEU16785.1 - 1.2 8.5 8.8 4.7 6.6 8.8 2.1 1 1 0 1 1 1 0 Ceramidase CPBP PF02517.16 OEU16785.1 - 8.2 6.9 7.6 19 5.7 7.6 2.0 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease RWD PF05773.22 OEU16786.1 - 2.5e-09 37.4 0.1 6.2e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 OEU16786.1 - 1.2e-08 35.2 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) UQ_con PF00179.26 OEU16786.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme DUF4279 PF14106.6 OEU16787.1 - 0.065 13.5 0.6 20 5.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) LSM PF01423.22 OEU16789.1 - 3.5e-22 77.8 0.0 4.4e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Reprolysin_5 PF13688.6 OEU16790.1 - 0.0026 17.9 0.1 0.0026 17.9 0.1 2.8 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OEU16790.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 OEU16790.1 - 0.006 16.5 0.3 0.012 15.5 0.3 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Metallopep PF12044.8 OEU16790.1 - 0.0076 14.9 0.0 0.025 13.2 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M57 PF12388.8 OEU16790.1 - 0.008 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 OEU16790.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OEU16790.1 - 0.023 15.2 1.9 0.036 14.6 0.0 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU16790.1 - 0.025 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 OEU16790.1 - 0.13 11.4 2.5 0.15 11.2 0.8 1.9 2 1 0 2 2 2 0 Met-zincin AD PF09793.9 OEU16792.1 - 6.9e-20 71.0 0.0 1.1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 OEU16792.1 - 0.00051 19.6 0.5 0.0019 17.7 0.5 1.8 1 1 0 1 1 1 1 Gemin6 protein Usher_TcfC PF17271.2 OEU16792.1 - 0.004 16.0 0.8 0.006 15.4 0.8 1.2 1 0 0 1 1 1 1 TcfC Usher-like barrel domain Cons_hypoth95 PF03602.15 OEU16792.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Sas10 PF09368.10 OEU16793.1 - 1.6e-24 86.1 7.5 1.6e-24 86.1 7.5 2.6 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OEU16793.1 - 0.011 16.4 0.2 0.011 16.4 0.2 3.2 3 0 0 3 3 3 0 Sas10/Utp3/C1D family SNAPc_SNAP43 PF09808.9 OEU16793.1 - 0.61 10.0 2.9 2.1 8.2 2.9 1.9 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 FYVE PF01363.21 OEU16795.1 - 2.2e-17 62.9 8.9 2.4e-17 62.8 8.9 1.0 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 OEU16795.1 - 0.0056 16.9 4.4 0.0076 16.5 4.4 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 OEU16795.1 - 0.31 11.3 5.1 0.31 11.2 5.1 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CRD PF17979.1 OEU16795.1 - 0.49 10.5 7.1 0.48 10.5 7.1 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-H2C2_2 PF13465.6 OEU16795.1 - 0.54 10.8 11.8 2.1 8.9 0.1 3.7 2 2 2 4 4 4 0 Zinc-finger double domain Nudix_N_2 PF14803.6 OEU16795.1 - 4.6 7.2 16.4 4.1 7.4 0.1 3.3 2 1 1 3 3 3 0 Nudix N-terminal XAF1_C PF18608.1 OEU16795.1 - 7.2 6.2 9.4 2.2 7.9 4.2 2.2 1 1 1 2 2 2 0 XIAP-associated factor 1 C-terminal domain MOSC PF03473.17 OEU16796.1 - 1.6e-10 41.1 0.0 3.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OEU16796.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.5 1 1 0 1 1 1 0 MOSC N-terminal beta barrel domain A_deaminase PF00962.22 OEU16797.1 - 1.7e-34 119.6 0.0 3e-20 72.8 0.0 2.4 2 1 0 2 2 2 2 Adenosine/AMP deaminase Uteroglobin PF01099.17 OEU16797.1 - 0.1 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Uteroglobin family DUF647 PF04884.14 OEU16798.1 - 7.3e-55 186.2 1.2 8e-55 186.1 1.2 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RNase_PH PF01138.21 OEU16799.1 - 1.5e-11 44.9 0.0 3.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OEU16799.1 - 0.00072 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 G10 PF01125.17 OEU16800.1 - 4.8e-53 178.9 1.6 5.3e-53 178.7 1.6 1.0 1 0 0 1 1 1 1 G10 protein MCM PF00493.23 OEU16801.1 - 5.5e-99 329.8 0.0 3e-98 327.4 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OEU16801.1 - 1.8e-34 118.3 2.8 3.4e-34 117.4 2.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OEU16801.1 - 5.1e-26 90.9 0.1 1.1e-25 89.8 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OEU16801.1 - 4.9e-08 32.6 0.2 0.00017 21.0 0.0 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU16801.1 - 1.2e-06 28.6 0.0 4e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OEU16801.1 - 1.6e-05 24.8 0.0 0.0002 21.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OEU16801.1 - 0.0015 18.2 0.2 0.72 9.5 0.0 3.0 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_16 PF13191.6 OEU16801.1 - 0.17 12.3 1.7 3.3 8.1 0.1 2.9 2 2 1 3 3 3 0 AAA ATPase domain Zn-ribbon_8 PF09723.10 OEU16801.1 - 1.1 9.4 5.0 2.9 8.1 5.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Pyr_redox_2 PF07992.14 OEU16802.1 - 2.8e-05 23.5 0.0 4.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU16802.1 - 3.2e-05 24.0 0.0 0.0051 16.8 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OEU16802.1 - 0.00017 20.9 0.0 0.00065 18.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OEU16802.1 - 0.00021 20.6 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU16802.1 - 0.0014 18.8 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU16802.1 - 0.0097 15.2 0.0 0.077 12.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 OEU16802.1 - 0.05 14.1 0.0 0.73 10.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding MRP_L53 PF10780.9 OEU16805.1 - 5.2e-08 32.9 0.0 8.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF2977 PF11192.8 OEU16805.1 - 0.14 12.3 1.3 0.2 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Ank_5 PF13857.6 OEU16806.1 - 3.4e-12 46.3 3.5 3.5e-07 30.4 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU16806.1 - 1.2e-09 38.6 0.7 4e-06 27.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU16806.1 - 5.2e-09 36.5 2.4 0.037 14.6 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU16806.1 - 1.1e-07 32.0 0.5 0.21 12.1 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OEU16806.1 - 3.1e-06 27.1 3.1 0.093 13.3 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat SET PF00856.28 OEU16807.1 - 7.2e-07 29.7 0.1 4.2e-05 24.0 0.1 2.5 1 1 0 1 1 1 1 SET domain Abhydrolase_6 PF12697.7 OEU16808.1 - 1.2e-14 55.4 0.0 1.7e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU16808.1 - 3.4e-08 33.1 0.0 1.6e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU16808.1 - 2e-05 24.4 0.0 0.00051 19.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 OEU16808.1 - 0.0082 15.7 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Pox_I3 PF04661.12 OEU16808.1 - 0.022 13.9 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein Lipase_2 PF01674.18 OEU16808.1 - 0.026 14.1 0.0 0.28 10.7 0.0 2.4 2 1 0 2 2 2 0 Lipase (class 2) PGAP1 PF07819.13 OEU16808.1 - 0.1 12.3 0.2 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein SlyX PF04102.12 OEU16809.1 - 0.00016 22.2 13.0 0.025 15.2 0.1 4.3 4 0 0 4 4 4 2 SlyX Pox_A_type_inc PF04508.12 OEU16809.1 - 0.0065 16.3 2.5 1.1 9.3 0.3 3.4 2 1 1 3 3 3 1 Viral A-type inclusion protein repeat UPF0242 PF06785.11 OEU16809.1 - 0.0093 16.1 32.2 3 7.9 26.9 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus YgaB PF14182.6 OEU16809.1 - 0.09 13.2 0.8 0.09 13.2 0.8 4.0 2 1 3 5 5 5 0 YgaB-like protein TSC22 PF01166.18 OEU16809.1 - 0.1 13.0 0.7 0.1 13.0 0.7 5.1 3 1 1 4 4 4 0 TSC-22/dip/bun family zf-C2H2_aberr PF17017.5 OEU16809.1 - 0.25 11.5 2.2 0.31 11.2 0.9 1.7 2 0 0 2 2 2 0 Aberrant zinc-finger DUF3138 PF11336.8 OEU16809.1 - 0.31 9.6 1.5 0.45 9.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PKcGMP_CC PF16808.5 OEU16809.1 - 0.66 9.9 24.4 0.88 9.5 3.7 4.4 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 OEU16809.1 - 1.6 9.0 36.5 7.6 6.7 4.5 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) YabA PF06156.13 OEU16809.1 - 4.9 7.8 23.4 5.7 7.6 0.1 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 OEU16809.1 - 6.1 7.0 23.2 3.2 7.9 6.7 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 OEU16809.1 - 8.2 6.2 12.4 16 5.3 2.3 3.4 4 0 0 4 4 4 0 USP8 interacting Glycos_transf_1 PF00534.20 OEU16810.1 - 4.8e-06 26.2 0.0 1.6e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU16810.1 - 5.8e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OEU16810.1 - 0.019 15.3 0.1 0.062 13.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 zf-RING_UBOX PF13445.6 OEU16811.1 - 1e-05 25.4 14.7 2.2e-05 24.4 14.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OEU16811.1 - 7.8e-05 22.5 19.4 0.00015 21.6 19.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU16811.1 - 0.0044 17.3 19.0 0.0091 16.3 19.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OEU16811.1 - 0.095 12.9 20.0 0.18 12.0 20.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OEU16811.1 - 0.25 11.3 17.2 0.61 10.1 17.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU16811.1 - 0.62 10.0 15.7 1.1 9.2 15.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU16811.1 - 0.79 9.6 20.5 2.2 8.2 20.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU16811.1 - 3.8 7.9 11.7 13 6.2 11.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain ABC_tran PF00005.27 OEU16812.1 - 1.6e-30 106.4 0.0 3.6e-29 102.0 0.0 2.8 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 OEU16812.1 - 2.7e-20 73.2 2.6 2.7e-20 73.2 2.6 1.6 1 1 1 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 OEU16812.1 - 3.1e-06 26.8 1.8 0.018 14.5 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU16812.1 - 1.2e-05 25.2 0.1 0.0073 16.2 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OEU16812.1 - 0.0002 21.4 0.0 0.0031 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 OEU16812.1 - 0.0012 18.7 0.1 0.0092 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OEU16812.1 - 0.0028 17.4 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU16812.1 - 0.0029 17.6 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 OEU16812.1 - 0.0059 16.2 0.0 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OEU16812.1 - 0.012 16.2 0.0 0.012 16.2 0.0 2.6 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OEU16812.1 - 0.014 15.8 0.0 0.23 11.8 0.1 2.8 2 2 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 OEU16812.1 - 0.021 14.9 0.1 0.26 11.4 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase YfhO PF09586.10 OEU16812.1 - 0.039 12.2 1.1 0.06 11.6 1.1 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SRP54 PF00448.22 OEU16812.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OEU16812.1 - 0.065 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 OEU16812.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 OEU16812.1 - 0.12 12.6 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OEU16812.1 - 0.14 12.7 0.0 0.47 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain ERCC4 PF02732.15 OEU16813.1 - 5e-08 33.3 0.4 3e-07 30.8 0.1 2.5 2 1 1 3 3 3 1 ERCC4 domain BRI3BP PF14965.6 OEU16814.1 - 0.0044 16.5 0.7 0.0073 15.8 0.7 1.3 1 0 0 1 1 1 1 Negative regulator of p53/TP53 VEFS-Box PF09733.9 OEU16814.1 - 0.1 12.4 0.6 0.22 11.4 0.6 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein BSP_II PF05432.11 OEU16814.1 - 0.52 10.0 12.1 0.33 10.6 7.8 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Uds1 PF15456.6 OEU16814.1 - 10 6.3 10.0 1.6 8.9 4.9 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Exo_endo_phos PF03372.23 OEU16815.1 - 1.1e-23 84.0 0.2 2.9e-23 82.6 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PSCyt2 PF07583.11 OEU16815.1 - 4.8e-05 23.4 0.1 8.7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1549) zf-C6H2 PF15801.5 OEU16815.1 - 0.68 10.3 6.4 1.6 9.1 6.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CIA30 PF08547.12 OEU16816.1 - 8.7e-09 35.6 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Cystatin PF00031.21 OEU16816.1 - 0.00089 19.5 1.4 0.1 12.9 0.2 2.4 1 1 1 2 2 2 2 Cystatin domain Carb_kinase PF01256.17 OEU16817.1 - 1.4e-40 139.3 0.1 4.1e-27 95.2 0.0 2.5 1 1 1 2 2 2 2 Carbohydrate kinase CvfB_WH PF17783.1 OEU16818.1 - 8.9e-17 60.6 0.1 1.7e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 CvfB-like winged helix domain Cofac_haem_bdg PF04187.13 OEU16819.1 - 1.4e-11 44.8 0.0 2.1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN DUF969 PF06149.12 OEU16819.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF969) NuA4 PF09340.10 OEU16821.1 - 2.3e-09 37.0 0.1 7.6e-09 35.3 0.1 2.0 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 HMG_box PF00505.19 OEU16822.1 - 1.1e-37 128.2 8.9 7.4e-19 67.9 2.0 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU16822.1 - 1.2e-26 93.1 8.1 5.3e-14 52.6 1.7 2.3 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 OEU16822.1 - 7.3e-11 41.9 0.0 6.6e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 CHDNT (NUC034) domain Cas_GSU0053 PF09617.10 OEU16822.1 - 0.0097 15.9 0.1 0.16 11.9 0.1 2.1 1 1 1 2 2 2 1 CRISPR-associated protein GSU0053 (Cas_GSU0053) HMG_box_5 PF14887.6 OEU16822.1 - 0.075 13.0 6.1 2.4 8.2 0.3 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box 5 GEN1_C PF18380.1 OEU16822.1 - 1.1 10.2 10.1 3.2 8.7 0.5 2.6 2 1 1 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain TFIIA PF03153.13 OEU16824.1 - 0.0018 18.4 19.2 0.0027 17.8 19.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit cIII PF08134.11 OEU16830.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 cIII protein family Aldose_epim PF01263.20 OEU16831.1 - 3.5e-45 154.6 0.0 2.2e-44 152.0 0.0 1.9 1 1 0 1 1 1 1 Aldose 1-epimerase Big_3_5 PF16640.5 OEU16831.1 - 0.022 14.9 0.1 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Methyltransf_PK PF05891.12 OEU16832.1 - 7.1e-62 208.8 0.0 8.4e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OEU16832.1 - 2.6e-05 24.8 0.0 4.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16832.1 - 0.017 15.7 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16832.1 - 0.048 14.4 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.9 OEU16833.1 - 7 6.2 27.7 0.17 11.4 17.3 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SAP PF02037.27 OEU16834.1 - 0.00044 19.9 0.1 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 SAP domain bZIP_1 PF00170.21 OEU16834.1 - 0.08 13.0 0.9 0.18 11.9 0.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor NAD_binding_9 PF13454.6 OEU16834.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding RHD_DNA_bind PF00554.22 OEU16835.1 - 0.1 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Rel homology DNA-binding domain Invasin_D3 PF09134.10 OEU16835.1 - 0.11 12.9 1.5 0.67 10.3 0.2 2.1 2 0 0 2 2 2 0 Invasin, domain 3 Methyltransf_25 PF13649.6 OEU16836.1 - 8e-14 52.1 0.0 1.7e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU16836.1 - 5.7e-11 42.5 0.0 7.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU16836.1 - 1.4e-10 41.8 0.0 2.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16836.1 - 5.8e-10 39.7 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU16836.1 - 5.6e-09 35.7 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU16836.1 - 1.7e-08 34.4 0.1 2.6e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 OEU16836.1 - 4.5e-06 26.0 0.0 6.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme NodS PF05401.11 OEU16836.1 - 0.0049 16.5 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 OEU16836.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Tox-PL-2 PF15643.6 OEU16836.1 - 0.12 12.6 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 Pkinase PF00069.25 OEU16837.1 - 2.5e-68 230.3 0.0 2.9e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16837.1 - 2.3e-31 109.0 0.0 2.9e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OEU16837.1 - 4.4e-06 27.3 4.1 1.1e-05 26.0 4.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OEU16837.1 - 5.8e-06 25.8 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OEU16837.1 - 0.00036 19.6 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OEU16837.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 OEU16838.1 - 2.8e-25 88.7 0.4 3.9e-19 69.0 0.4 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU16838.1 - 6.7e-25 87.1 6.0 7.8e-12 45.5 0.1 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU16838.1 - 7.9e-20 70.7 3.8 2.1e-08 34.3 0.1 4.7 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU16838.1 - 3e-16 57.9 1.6 3e-06 27.1 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OEU16838.1 - 3.1e-16 59.0 5.7 4.5e-08 33.2 0.1 4.2 5 0 0 5 5 5 2 Ankyrin repeat Mito_carr PF00153.27 OEU16839.1 - 1.7e-15 56.7 8.4 1.6e-05 24.7 0.2 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein PHD PF00628.29 OEU16841.1 - 5.4e-10 39.0 5.7 5.4e-10 39.0 5.7 1.9 2 0 0 2 2 2 1 PHD-finger Pyr_redox_2 PF07992.14 OEU16842.1 - 2.3e-29 102.6 0.0 8.2e-22 77.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU16842.1 - 3.6e-20 72.3 2.1 7.5e-13 48.9 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU16842.1 - 3e-14 53.2 0.0 5.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain AlaDh_PNT_C PF01262.21 OEU16842.1 - 1e-05 24.9 0.0 0.1 11.9 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OEU16842.1 - 0.00015 21.4 2.7 0.005 16.5 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU16842.1 - 0.00051 19.4 2.5 0.12 11.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain 2-Hacid_dh_C PF02826.19 OEU16842.1 - 0.00055 19.3 0.0 0.046 13.1 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OEU16842.1 - 0.0014 17.8 1.3 0.17 11.0 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OEU16842.1 - 0.0045 17.4 0.1 3.8 8.0 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OEU16842.1 - 0.0085 15.4 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU16842.1 - 0.012 15.0 3.6 0.061 12.7 0.7 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OEU16842.1 - 0.033 13.2 0.2 0.076 12.1 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 OEU16842.1 - 0.078 13.5 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_2 PF00890.24 OEU16842.1 - 0.12 11.4 0.1 0.12 11.4 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.14 OEU16842.1 - 0.15 10.7 0.1 0.34 9.6 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 OEU16842.1 - 0.2 11.5 0.5 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OEU16842.1 - 0.28 11.5 0.6 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 OEU16842.1 - 0.42 10.9 3.0 19 5.6 0.2 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 OEU16843.1 - 6.8e-40 136.9 0.0 9.5e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4598 PF15370.6 OEU16844.1 - 0.025 15.0 0.2 0.059 13.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) DIRP PF06584.13 OEU16845.1 - 1.6e-11 44.3 1.7 2.8e-11 43.5 0.2 2.3 2 0 0 2 2 2 1 DIRP zf-RING_5 PF14634.6 OEU16846.1 - 1.6e-06 28.0 7.7 1.6e-06 28.0 7.7 4.0 4 0 0 4 4 4 1 zinc-RING finger domain IBR PF01485.21 OEU16846.1 - 1.7e-06 28.2 12.8 1.7e-06 28.2 12.8 5.2 3 2 3 6 6 6 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OEU16846.1 - 1.2e-05 25.0 10.7 1.2e-05 25.0 10.7 5.6 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU16846.1 - 0.00015 22.0 13.0 0.00015 22.0 13.0 5.2 3 2 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 OEU16846.1 - 0.00028 20.9 7.6 0.00028 20.9 7.6 4.2 2 2 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU16846.1 - 0.027 14.6 2.3 0.027 14.6 2.3 5.0 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING MMR_HSR1 PF01926.23 OEU16847.1 - 1.4e-20 73.4 0.0 3.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OEU16847.1 - 7.9e-18 64.3 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OEU16847.1 - 4.5e-10 39.3 0.0 7.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU16847.1 - 0.00019 21.5 0.0 0.1 12.6 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 OEU16847.1 - 0.0003 20.2 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_28 PF13521.6 OEU16847.1 - 0.032 14.5 0.5 0.078 13.2 0.5 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OEU16847.1 - 0.072 12.5 0.2 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 OEU16847.1 - 0.079 12.7 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU16847.1 - 0.12 12.8 0.1 0.27 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OEU16847.1 - 0.12 11.9 0.7 13 5.3 0.1 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Methyltransf_32 PF13679.6 OEU16848.1 - 7.9e-17 61.7 0.2 7.9e-17 61.7 0.2 2.9 3 1 0 3 3 3 1 Methyltransferase domain TRM13 PF05206.14 OEU16848.1 - 8.3e-14 51.7 1.9 2.9e-13 50.0 0.1 2.6 3 0 0 3 3 3 1 Methyltransferase TRM13 MTS PF05175.14 OEU16848.1 - 4.2e-05 23.2 0.0 9.6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 OEU16848.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 OEU16848.1 - 0.00099 19.8 2.2 0.0039 17.9 0.0 3.1 3 1 1 4 4 4 1 Methyltransferase domain R3H PF01424.22 OEU16848.1 - 0.0014 18.6 0.0 0.0056 16.6 0.0 2.0 2 0 0 2 2 2 1 R3H domain Methyltransf_25 PF13649.6 OEU16848.1 - 0.0027 18.4 0.0 0.0079 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OEU16848.1 - 0.0065 15.8 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 OEU16848.1 - 0.0065 16.3 0.1 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 OEU16848.1 - 0.02 14.6 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 OEU16848.1 - 0.11 12.3 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain OGG_N PF07934.12 OEU16849.1 - 5e-23 81.5 0.0 1.8e-22 79.7 0.0 2.0 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OEU16849.1 - 1.7e-11 44.5 0.0 3.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ferlin_C PF16165.5 OEU16849.1 - 0.035 14.1 3.0 0.061 13.3 3.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Stealth_CR4 PF17103.5 OEU16849.1 - 0.055 13.4 3.0 18 5.3 0.0 3.4 3 0 0 3 3 3 0 Stealth protein CR4, conserved region 4 DUF308 PF03729.13 OEU16850.1 - 6.1e-12 45.7 28.3 1.4e-06 28.6 10.6 3.2 2 1 1 3 3 3 3 Short repeat of unknown function (DUF308) DUF4267 PF14087.6 OEU16850.1 - 0.38 10.9 6.2 2.2 8.4 6.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Spore_YhaL PF14147.6 OEU16850.1 - 1.4 8.6 3.9 4.3 7.1 3.9 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL PGPGW PF09656.10 OEU16850.1 - 4.5 6.9 13.2 3.1 7.4 3.2 3.5 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) PfkB PF00294.24 OEU16851.1 - 7.5e-25 87.8 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Rpn3_C PF08375.11 OEU16852.1 - 9.5e-24 83.6 0.4 1.8e-23 82.8 0.4 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OEU16852.1 - 1.2e-15 57.9 0.0 2.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OEU16852.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family RRM_1 PF00076.22 OEU16853.1 - 2.6e-55 184.1 0.0 3.1e-20 71.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU16853.1 - 4e-07 30.1 0.1 0.12 12.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OEU16853.1 - 0.0059 16.6 0.1 0.85 9.7 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1179 PF06678.11 OEU16854.1 - 0.021 14.8 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) His_Phos_1 PF00300.22 OEU16855.1 - 0.14 11.8 7.8 0.11 12.1 5.3 2.0 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) Chromo PF00385.24 OEU16855.1 - 1.2 9.1 7.5 2.9 7.9 0.7 2.6 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RXT2_N PF08595.11 OEU16855.1 - 1.2 9.1 7.3 2.7 8.0 7.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal HSF_DNA-bind PF00447.17 OEU16856.1 - 5.7e-28 97.4 1.3 1.1e-27 96.4 1.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMEM18 PF14770.6 OEU16857.1 - 4.6e-36 123.4 1.3 6e-36 123.0 1.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF4752 PF15944.5 OEU16857.1 - 0.0061 16.6 0.3 3.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4752) 7tm_3 PF00003.22 OEU16857.1 - 0.023 14.5 0.0 0.048 13.4 0.1 1.5 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Ribosomal_L5e PF17144.4 OEU16858.1 - 1.9e-78 262.1 0.3 1.9e-78 262.1 0.3 2.0 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OEU16858.1 - 6.8e-30 103.9 2.0 6.8e-30 103.9 2.0 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region CpeT PF06206.11 OEU16858.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) PAZ PF02170.22 OEU16858.1 - 0.039 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 PAZ domain zf-RING_2 PF13639.6 OEU16859.1 - 8.9e-09 35.5 8.5 1.7e-08 34.6 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU16859.1 - 1.2e-05 25.5 7.7 3.3e-05 24.1 7.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU16859.1 - 1.3e-05 24.9 7.9 2.6e-05 24.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU16859.1 - 7.5e-05 22.5 6.4 0.00017 21.3 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU16859.1 - 9.2e-05 22.4 3.0 0.00021 21.3 3.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OEU16859.1 - 0.00015 21.3 4.3 0.0003 20.3 4.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OEU16859.1 - 0.00022 21.1 6.9 0.00039 20.3 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OEU16859.1 - 0.00023 20.8 1.4 0.00023 20.8 1.4 1.9 2 0 0 2 2 1 1 RING-like zinc finger FANCL_C PF11793.8 OEU16859.1 - 0.00073 19.7 5.2 0.0028 17.8 5.2 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 OEU16859.1 - 0.00079 19.2 1.5 0.0016 18.2 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_9 PF13901.6 OEU16859.1 - 0.0021 18.1 1.5 0.0021 18.1 1.5 1.6 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon zf-RING_UBOX PF13445.6 OEU16859.1 - 0.0032 17.5 2.8 0.0087 16.1 2.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.7 OEU16859.1 - 0.078 13.1 7.2 0.16 12.1 7.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 OEU16859.1 - 0.28 11.1 6.5 0.62 10.0 6.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OEU16859.1 - 0.81 10.1 5.1 1.9 8.9 5.1 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OEU16859.1 - 4.6 7.4 7.4 18 5.5 7.4 2.0 1 1 0 1 1 1 0 Zinc-finger DAO PF01266.24 OEU16860.1 - 8.8e-29 101.2 0.2 1.8e-19 70.6 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU16860.1 - 0.00024 21.2 0.5 0.00064 19.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU16860.1 - 0.0062 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OEU16860.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 OEU16860.1 - 0.044 13.0 0.3 0.083 12.1 0.3 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 OEU16860.1 - 0.074 11.8 0.0 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 MCRA family AlaDh_PNT_C PF01262.21 OEU16860.1 - 0.11 11.7 0.3 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OEU16860.1 - 0.14 12.2 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OEU16860.1 - 0.17 12.2 0.3 2.2 8.6 0.1 2.2 1 1 1 2 2 2 0 TrkA-N domain DUF695 PF05117.12 OEU16860.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF695) Ammonium_transp PF00909.21 OEU16861.1 - 2.5e-22 79.1 10.2 5.4e-22 78.0 10.2 1.4 1 1 0 1 1 1 1 Ammonium Transporter Family HCV_core PF01542.18 OEU16861.1 - 0.038 14.4 0.2 0.038 14.4 0.2 2.5 2 1 1 3 3 3 0 Hepatitis C virus core protein Vma12 PF11712.8 OEU16861.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2104 PF09877.9 OEU16861.1 - 0.28 11.5 3.9 2.6 8.4 0.3 2.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2104) ATPase_gene1 PF09527.10 OEU16861.1 - 8.4 6.7 13.5 0.64 10.2 1.7 3.2 3 1 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1499 PF07386.11 OEU16862.1 - 3.7e-09 37.2 0.8 6.8e-09 36.3 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) PLRV_ORF5 PF01690.17 OEU16862.1 - 0.035 12.8 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Phytochelatin PF05023.14 OEU16863.1 - 3.6e-83 278.0 0.0 5.4e-83 277.4 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Ras_bdg_2 PF14847.6 OEU16863.1 - 0.13 12.6 0.9 0.76 10.1 0.4 2.2 2 0 0 2 2 2 0 Ras-binding domain of Byr2 FAM176 PF14851.6 OEU16863.1 - 0.48 10.1 2.7 0.87 9.2 0.2 2.1 2 0 0 2 2 2 0 FAM176 family Sod_Fe_N PF00081.22 OEU16864.1 - 4.9e-32 110.2 0.4 7.3e-32 109.7 0.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 OEU16864.1 - 1.3e-14 54.1 1.7 8.3e-13 48.4 0.7 2.5 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain RIBIOP_C PF04950.12 OEU16865.1 - 1.8e-84 283.6 0.0 1.8e-84 283.6 0.0 1.7 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OEU16865.1 - 2e-28 98.3 0.1 8.5e-28 96.3 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 OEU16865.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pex19 PF04614.12 OEU16866.1 - 5.2e-26 91.9 4.8 5.6e-26 91.8 4.8 1.0 1 0 0 1 1 1 1 Pex19 protein family STAT_int PF02865.17 OEU16866.1 - 0.0072 16.8 1.0 0.0082 16.6 1.0 1.1 1 0 0 1 1 1 1 STAT protein, protein interaction domain ING PF12998.7 OEU16866.1 - 0.026 15.1 0.1 0.035 14.7 0.1 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding UFC1 PF08694.11 OEU16866.1 - 0.043 13.5 0.7 0.051 13.2 0.7 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 SpoIIP PF07454.11 OEU16867.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Ank_2 PF12796.7 OEU16867.1 - 0.05 14.2 0.3 0.19 12.3 0.3 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU16867.1 - 0.059 14.0 0.2 0.2 12.3 0.1 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) NAD_binding_6 PF08030.12 OEU16869.1 - 0.0003 20.9 0.3 0.00065 19.8 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Corona_5a PF06336.11 OEU16869.1 - 0.14 12.2 0.2 0.33 11.0 0.2 1.6 1 0 0 1 1 1 0 Coronavirus 5a protein Ferric_reduct PF01794.19 OEU16869.1 - 4.3 7.5 9.4 0.62 10.2 4.5 2.0 2 1 0 2 2 2 0 Ferric reductase like transmembrane component UCH PF00443.29 OEU16870.1 - 1.7e-38 132.6 9.9 1.7e-38 132.6 9.9 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CCDC-167 PF15188.6 OEU16870.1 - 0.59 10.5 6.0 4.8 7.6 4.6 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Ank_2 PF12796.7 OEU16871.1 - 1.2e-07 32.2 0.0 0.0012 19.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU16871.1 - 0.00062 20.0 0.1 25 5.9 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OEU16871.1 - 0.087 13.2 0.7 8.2 6.9 0.2 4.2 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Aldo_ket_red PF00248.21 OEU16873.1 - 2.8e-41 141.6 0.0 8e-34 117.2 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family zf-CCCH_4 PF18044.1 OEU16874.1 - 6.5e-12 45.0 3.5 1.1e-11 44.3 3.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OEU16874.1 - 3.1e-08 33.4 8.3 5.1e-08 32.7 8.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OEU16874.1 - 6.4e-08 32.3 4.1 1.1e-07 31.5 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OEU16874.1 - 9.4e-05 23.1 0.8 0.00012 22.7 0.8 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 OEU16874.1 - 0.00083 19.7 7.1 0.0014 19.1 7.1 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Drf_FH1 PF06346.12 OEU16874.1 - 0.014 15.1 16.2 0.018 14.8 16.2 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 zf-CCCH_3 PF15663.5 OEU16874.1 - 0.083 13.1 0.4 0.12 12.6 0.4 1.2 1 0 0 1 1 1 0 Zinc-finger containing family Ribosomal_L7Ae PF01248.26 OEU16875.1 - 1e-11 44.4 0.2 1.8e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UBA2_C PF16195.5 OEU16875.1 - 0.013 16.2 0.2 0.029 15.1 0.2 1.6 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF4710 PF15828.5 OEU16875.1 - 0.14 12.3 0.8 3 8.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4710) MFS_1 PF07690.16 OEU16877.1 - 2.1e-11 43.4 27.1 6e-06 25.4 1.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Fe_bilin_red PF05996.12 OEU16878.1 - 1.4e-27 96.9 0.1 1.4e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 Ferredoxin-dependent bilin reductase DUF4978 PF16349.5 OEU16878.1 - 0.0026 17.4 0.3 0.0056 16.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4978) Thioredoxin_8 PF13905.6 OEU16878.1 - 0.0035 17.6 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Img2 PF05046.14 OEU16878.1 - 0.094 13.0 0.1 1.2 9.5 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) NUDIX PF00293.28 OEU16879.1 - 0.00031 20.8 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Glutaredoxin PF00462.24 OEU16880.1 - 1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Arf PF00025.21 OEU16881.1 - 2.7e-74 248.4 0.0 3e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OEU16881.1 - 6e-15 55.5 0.0 8.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OEU16881.1 - 6.6e-12 45.3 0.0 7.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OEU16881.1 - 9e-12 44.8 0.1 1e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OEU16881.1 - 3.8e-11 42.8 0.0 4.8e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OEU16881.1 - 6.5e-08 32.7 0.0 9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OEU16881.1 - 4.7e-07 29.4 0.0 5.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OEU16881.1 - 6.9e-05 22.4 0.2 0.00052 19.6 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 OEU16881.1 - 0.006 17.1 0.0 0.018 15.6 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Morc6_S5 PF17942.1 OEU16881.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like AAA_18 PF13238.6 OEU16881.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OEU16881.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF456 PF04306.13 OEU16882.1 - 0.00022 21.5 0.9 0.00037 20.8 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF1269 PF06897.12 OEU16882.1 - 0.016 15.5 1.2 0.031 14.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Dynamin_N PF00350.23 OEU16883.1 - 7.6e-24 84.6 1.4 5.9e-23 81.8 1.0 2.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OEU16883.1 - 3.7e-14 52.8 0.9 1e-13 51.4 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU16883.1 - 6e-11 42.2 0.6 6.1e-10 39.0 0.6 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU16883.1 - 1.4e-06 28.3 2.9 0.00015 21.7 0.3 3.1 3 0 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OEU16883.1 - 0.00044 19.8 0.4 0.17 11.4 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B Septin PF00735.18 OEU16883.1 - 0.0008 18.8 0.2 0.0057 16.0 0.0 2.4 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 OEU16883.1 - 0.0047 17.4 0.0 0.018 15.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.16 OEU16883.1 - 0.011 15.1 2.1 1.5 8.1 0.4 2.4 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.17 OEU16883.1 - 0.02 14.7 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OEU16883.1 - 0.056 13.2 0.0 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 OEU16883.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPC PF04151.15 OEU16884.1 - 0.061 14.4 0.1 0.061 14.4 0.1 5.1 3 2 2 5 5 5 0 Bacterial pre-peptidase C-terminal domain Topo-VIb_trans PF09239.11 OEU16885.1 - 5.8e-55 185.5 0.0 1.1e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 OEU16885.1 - 8.2e-08 32.2 0.2 5.2e-06 26.3 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OEU16885.1 - 3.7e-06 27.4 0.0 1.5e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF29 PF01724.16 OEU16885.1 - 0.00099 19.4 1.7 0.82 9.9 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF29 PALP PF00291.25 OEU16886.1 - 3.9e-57 193.9 0.0 2.2e-56 191.5 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 7tm_3 PF00003.22 OEU16887.1 - 3.2e-22 79.4 20.3 4.1e-22 79.1 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1345 PF07077.11 OEU16887.1 - 0.028 14.1 6.8 0.65 9.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Rad1 PF02144.16 OEU16888.1 - 2e-13 50.1 1.6 8e-13 48.1 1.6 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RNA_ligase PF09414.10 OEU16889.1 - 2.6e-06 27.8 0.0 4.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase ATP_bind_3 PF01171.20 OEU16890.1 - 1.1e-26 93.7 0.0 1.5e-25 90.1 0.0 2.6 2 1 0 2 2 2 1 PP-loop family DUF924 PF06041.11 OEU16890.1 - 6.9e-11 42.6 0.6 4.8e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF924) QueC PF06508.13 OEU16890.1 - 0.0018 17.8 0.0 0.024 14.1 0.0 2.2 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 OEU16890.1 - 0.0025 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase XRN_M PF17846.1 OEU16890.1 - 0.12 11.3 0.8 0.21 10.5 0.8 1.3 1 0 0 1 1 1 0 Xrn1 helical domain PK PF00224.21 OEU16892.1 - 1.1e-104 350.1 0.0 1.4e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OEU16892.1 - 1.1e-26 93.4 0.0 2.4e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Terminase_1 PF03354.15 OEU16892.1 - 0.19 10.2 0.0 0.51 8.8 0.0 1.6 2 0 0 2 2 2 0 Phage Terminase PMSR PF01625.21 OEU16893.1 - 1.1e-15 58.2 0.1 1.6e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TNFR_16_TM PF18422.1 OEU16893.1 - 0.024 14.6 2.0 0.045 13.7 2.0 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Epiglycanin_C PF14654.6 OEU16893.1 - 2.1 8.4 3.7 4.5 7.4 3.3 1.7 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Sulfate_transp PF00916.20 OEU16894.1 - 4.4e-45 154.1 22.6 4.4e-45 154.1 22.6 1.9 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 OEU16894.1 - 3.9e-05 23.3 0.2 7.8e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 STAS domain QCR10 PF09796.9 OEU16894.1 - 0.15 12.1 5.8 0.2 11.7 0.7 3.8 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RRP36 PF06102.12 OEU16896.1 - 2.6e-30 105.6 11.7 2.6e-30 105.6 11.7 2.3 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Hydrolase_like PF13242.6 OEU16896.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like LRR_4 PF12799.7 OEU16897.1 - 2.1 8.9 19.3 3.2 8.3 0.3 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) GRP PF07172.11 OEU16899.1 - 0.053 14.2 4.0 0.76 10.5 3.4 2.4 2 0 0 2 2 2 0 Glycine rich protein family Androgen_recep PF02166.16 OEU16900.1 - 0.00052 19.0 2.1 0.00093 18.1 2.1 1.3 1 0 0 1 1 1 1 Androgen receptor HEM4 PF02602.15 OEU16900.1 - 0.015 14.7 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD FAM177 PF14774.6 OEU16900.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.1 3 0 0 3 3 3 0 FAM177 family Flg_bb_rod PF00460.20 OEU16900.1 - 2.3 8.3 4.2 1.9 8.5 0.4 2.6 3 0 0 3 3 3 0 Flagella basal body rod protein F-box-like PF12937.7 OEU16901.1 - 8.4e-07 28.8 0.1 2.6e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like BRF1 PF07741.13 OEU16901.1 - 0.0054 17.0 5.3 0.0094 16.3 5.3 1.3 1 0 0 1 1 1 1 Brf1-like TBP-binding domain F-box PF00646.33 OEU16901.1 - 0.0067 16.3 0.6 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain SdrD_B PF17210.3 OEU16901.1 - 0.0079 16.4 0.4 0.016 15.4 0.0 1.6 2 0 0 2 2 2 1 SdrD B-like domain DUSP PF06337.12 OEU16901.1 - 0.057 14.0 0.3 0.11 13.1 0.3 1.5 1 0 0 1 1 1 0 DUSP domain PLAC8 PF04749.17 OEU16902.1 - 4.1e-05 24.5 16.6 5.4e-05 24.1 16.6 1.1 1 0 0 1 1 1 1 PLAC8 family DUF2054 PF10218.9 OEU16902.1 - 6.9 6.8 24.3 0.046 13.8 7.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2054) Peptidase_S28 PF05577.12 OEU16903.1 - 4.2e-67 226.8 0.1 5.3e-51 173.8 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 OEU16903.1 - 0.0004 19.7 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 OEU16903.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 OEU16903.1 - 0.0017 17.9 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OEU16903.1 - 0.026 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase RsdA_SigD_bd PF16751.5 OEU16904.1 - 0.12 12.6 1.1 0.24 11.7 1.1 1.4 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region SLC35F PF06027.12 OEU16905.1 - 8.3e-45 153.6 13.8 2e-39 135.9 8.8 2.3 2 1 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 OEU16905.1 - 0.00034 19.7 0.6 0.00034 19.7 0.6 1.7 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 OEU16905.1 - 0.18 11.0 7.9 0.019 14.2 3.7 1.4 2 0 0 2 2 2 0 UAA transporter family DUF3938 PF13074.6 OEU16905.1 - 0.66 10.3 6.0 6.9 7.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) TMEM100 PF16311.5 OEU16905.1 - 6.4 6.4 7.0 36 4.0 0.7 3.3 3 0 0 3 3 3 0 Transmembrane protein 100 Thioredoxin PF00085.20 OEU16906.1 - 2e-19 69.5 0.0 2.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU16906.1 - 1.9e-06 27.9 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OEU16906.1 - 6.5e-05 22.4 0.1 7.4e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OEU16906.1 - 8.2e-05 23.0 0.2 0.0003 21.2 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU16906.1 - 0.00082 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OEU16906.1 - 0.0031 17.4 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 OEU16906.1 - 0.0081 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 OEU16906.1 - 0.0082 16.5 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU16906.1 - 0.013 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF2306 PF10067.9 OEU16907.1 - 7.5e-05 23.0 8.1 7.5e-05 23.0 8.1 3.3 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF2681 PF10883.8 OEU16907.1 - 0.0056 17.1 0.0 0.047 14.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) WBP-1 PF11669.8 OEU16907.1 - 0.093 13.4 1.9 1.7 9.3 0.3 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF4405 PF14358.6 OEU16907.1 - 6.2 7.4 8.4 1.6 9.3 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) ubiquitin PF00240.23 OEU16909.1 - 2.7e-72 238.5 16.9 1.6e-12 47.0 0.2 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 OEU16909.1 - 9.1e-35 118.3 29.8 1.2e-06 28.2 0.0 6.1 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OEU16909.1 - 4.7e-12 45.7 0.0 0.016 15.1 0.0 6.0 4 1 2 6 6 6 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 OEU16909.1 - 8e-12 45.5 10.6 0.00067 20.1 0.1 6.0 5 1 1 6 6 6 3 Ubiquitin-like domain UN_NPL4 PF11543.8 OEU16909.1 - 1.5e-10 41.4 0.0 0.0016 18.9 0.0 5.5 3 2 2 5 5 5 2 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 OEU16909.1 - 1.6e-08 34.4 11.5 1.5 8.9 0.0 7.1 6 1 1 7 7 7 3 Ubiquitin-like domain UBX PF00789.20 OEU16909.1 - 0.0002 21.5 3.0 1.2 9.4 0.0 5.2 4 2 2 6 6 6 1 UBX domain DUF4957 PF16318.5 OEU16909.1 - 0.00085 19.3 1.2 7.4 6.5 0.0 4.2 1 1 2 4 4 4 1 Domain of unknown function (DUF4957) YukD PF08817.10 OEU16909.1 - 0.0027 18.3 5.6 3.4 8.4 0.0 5.1 5 0 0 5 5 5 1 WXG100 protein secretion system (Wss), protein YukD TUG-UBL1 PF11470.8 OEU16909.1 - 0.0041 17.3 0.2 29 5.0 0.0 3.9 3 0 0 3 3 3 0 TUG ubiquitin-like domain UAE_UbL PF14732.6 OEU16909.1 - 0.025 15.2 1.3 12 6.6 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain RBD PF02196.15 OEU16909.1 - 0.026 14.6 0.7 42 4.3 0.0 4.6 4 1 1 5 5 5 0 Raf-like Ras-binding domain fn3_5 PF06280.12 OEU16909.1 - 0.043 14.5 0.5 7.6 7.3 0.0 3.1 2 1 1 3 3 3 0 Fn3-like domain PI3K_p85B PF02192.16 OEU16909.1 - 0.11 12.3 0.2 56 3.6 0.0 3.5 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 OEU16909.1 - 0.17 12.1 1.1 21 5.4 0.0 3.3 4 0 0 4 4 4 0 PI3-kinase family, ras-binding domain Ribosomal_L27A PF00828.19 OEU16911.1 - 4.8e-22 79.0 0.2 6.8e-22 78.5 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A P2X_receptor PF00864.19 OEU16911.1 - 0.067 12.3 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 ATP P2X receptor DUF5026 PF16429.5 OEU16911.1 - 0.25 11.4 0.9 0.41 10.8 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Pribosyltran_N PF13793.6 OEU16912.1 - 7.1e-50 167.8 0.1 2.6e-49 166.0 0.0 1.9 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OEU16912.1 - 3.3e-26 92.4 0.0 1.4e-25 90.4 0.0 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OEU16912.1 - 1.6e-12 47.2 0.1 3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OEU16912.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Na_H_Exchanger PF00999.21 OEU16913.1 - 1.8e-41 142.2 28.6 2.8e-41 141.6 28.6 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Baculo_gp41 PF04700.12 OEU16914.1 - 0.0027 17.5 0.0 0.0086 15.9 0.0 1.8 1 1 1 2 2 2 1 Structural glycoprotein p40/gp41 conserved region TFCD_C PF12612.8 OEU16914.1 - 0.029 14.2 0.1 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Sigma70_r2 PF04542.14 OEU16915.1 - 1.6e-16 59.8 0.0 2.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 OEU16915.1 - 1.7e-14 53.7 0.4 1.5e-13 50.6 0.3 2.7 2 1 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 OEU16915.1 - 8e-08 31.7 0.3 1.9e-07 30.5 0.3 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 OEU16915.1 - 0.071 12.8 0.4 4.5 7.0 0.2 3.2 3 1 0 3 3 3 0 Sigma-70, region 4 Skp1_POZ PF03931.15 OEU16917.1 - 5.3e-09 36.1 0.0 7.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 OEU16917.1 - 0.00044 20.5 0.0 0.00051 20.3 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 OEU16918.1 - 1.4e-50 172.1 0.0 1.6e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16918.1 - 5.5e-38 130.7 0.0 6.4e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU16918.1 - 1.4e-08 34.0 0.0 1.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OEU16918.1 - 1.8e-07 30.8 0.0 2.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU16918.1 - 0.0027 17.7 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OEU16918.1 - 0.0041 16.1 0.1 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OEU16918.1 - 0.028 13.5 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OEU16918.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 OEU16919.1 - 1.1e-35 123.0 0.0 3e-35 121.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OEU16919.1 - 2.5e-09 37.5 0.2 0.00046 20.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 OEU16919.1 - 3e-06 27.7 0.2 0.00029 21.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OEU16919.1 - 1.3e-05 25.2 0.0 0.00058 19.9 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OEU16919.1 - 1.3e-05 24.9 0.0 4.1e-05 23.3 0.0 2.0 2 1 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 OEU16919.1 - 7.4e-05 22.5 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Vps4_C PF09336.10 OEU16919.1 - 0.00022 21.1 1.8 0.0004 20.3 0.1 2.3 4 0 0 4 4 1 1 Vps4 C terminal oligomerisation domain TniB PF05621.11 OEU16919.1 - 0.00026 20.5 0.0 0.12 11.7 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein RuvB_N PF05496.12 OEU16919.1 - 0.0003 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU16919.1 - 0.00088 19.8 0.0 0.0017 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OEU16919.1 - 0.0022 17.4 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OEU16919.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OEU16919.1 - 0.0031 17.6 0.0 0.0073 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OEU16919.1 - 0.004 17.1 0.0 0.018 15.0 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 OEU16919.1 - 0.0074 15.9 0.0 0.043 13.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 OEU16919.1 - 0.0093 15.5 0.0 0.031 13.8 0.0 1.9 2 1 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 OEU16919.1 - 0.0097 15.1 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 OEU16919.1 - 0.014 15.8 0.1 0.044 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU16919.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU16919.1 - 0.017 15.3 0.1 0.044 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OEU16919.1 - 0.019 14.3 0.0 0.098 12.0 0.0 1.9 1 1 1 2 2 2 0 KaiC MCM PF00493.23 OEU16919.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_11 PF13086.6 OEU16919.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OEU16919.1 - 0.035 13.8 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU16919.1 - 0.04 14.3 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 OEU16919.1 - 0.045 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OEU16919.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 OEU16919.1 - 0.052 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 OEU16919.1 - 0.065 13.1 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 OEU16919.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 OEU16919.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 OEU16919.1 - 0.075 13.5 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 ABC transporter DUF1860 PF08949.10 OEU16919.1 - 0.078 12.7 0.3 11 5.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1860) Transcrip_reg PF01709.20 OEU16919.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator ATPase_2 PF01637.18 OEU16919.1 - 0.087 12.7 0.0 0.49 10.3 0.0 2.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OEU16919.1 - 0.11 12.2 0.0 1.3 8.7 0.0 2.5 4 0 0 4 4 2 0 Sigma-54 interaction domain T2SSE PF00437.20 OEU16919.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Guanylate_kin PF00625.21 OEU16919.1 - 0.13 11.9 0.1 0.73 9.5 0.0 2.3 3 0 0 3 3 3 0 Guanylate kinase Myb_DNA-binding PF00249.31 OEU16921.1 - 5.9e-11 42.4 0.5 0.00035 20.7 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU16921.1 - 5.5e-09 36.1 0.1 0.0025 18.0 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain PHINT_rpt PF14882.6 OEU16921.1 - 3.2e-05 24.1 1.8 6.6e-05 23.1 1.8 1.5 1 0 0 1 1 1 1 Phage-integrase repeat unit DUF4770 PF15994.5 OEU16921.1 - 0.23 11.7 3.6 0.46 10.7 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 OEU16922.1 - 0.00022 22.1 4.1 0.0084 17.1 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) Spore_III_AF PF09581.10 OEU16922.1 - 0.00029 20.9 0.2 0.00055 20.0 0.2 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) JTB PF05439.12 OEU16922.1 - 0.91 9.6 13.2 0.66 10.0 8.7 2.7 2 1 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) GST_C_3 PF14497.6 OEU16924.1 - 3.7e-15 55.9 0.0 5.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU16924.1 - 4.7e-10 39.7 0.0 8.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU16924.1 - 7.3e-07 29.3 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU16924.1 - 3.9e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OEU16924.1 - 0.0038 17.5 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU16924.1 - 0.0038 17.6 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OEU16924.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5608 PF18356.1 OEU16924.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) TFIIS_M PF07500.14 OEU16925.1 - 1.7e-19 70.3 2.1 7.5e-19 68.3 2.1 2.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SeqA_N PF17206.3 OEU16925.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 SeqA protein N-terminal domain Presenilin PF01080.17 OEU16926.1 - 7.6e-99 331.2 1.4 2.7e-98 329.3 1.4 1.7 1 1 0 1 1 1 1 Presenilin Ycf1 PF05758.12 OEU16926.1 - 0.06 11.2 0.0 0.074 10.9 0.0 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_S15 PF02129.18 OEU16926.1 - 0.1 12.1 0.4 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RNA_pol_3_Rpc31 PF11705.8 OEU16926.1 - 0.11 12.7 12.4 0.19 11.9 12.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ATP-gua_Ptrans PF00217.19 OEU16926.1 - 0.14 11.6 0.1 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, C-terminal catalytic domain FAM60A PF15396.6 OEU16926.1 - 1.5 8.8 7.4 2.4 8.1 7.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 OEU16926.1 - 4.1 6.1 12.4 5.8 5.6 12.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dicty_REP PF05086.12 OEU16926.1 - 4.3 5.2 8.0 6.6 4.6 8.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1700 PF08006.11 OEU16926.1 - 4.5 6.8 10.5 0.13 11.8 2.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) Presenilin PF01080.17 OEU16927.1 - 1.6e-81 274.1 32.2 3.6e-48 164.3 15.8 2.0 1 1 1 2 2 2 2 Presenilin Dor1 PF04124.12 OEU16929.1 - 6.8e-33 113.8 11.9 1.5e-19 69.9 5.9 2.7 2 1 0 2 2 2 2 Dor1-like family Sec5 PF15469.6 OEU16929.1 - 0.024 14.4 0.3 0.058 13.2 0.3 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF4639 PF15479.6 OEU16929.1 - 0.091 11.7 0.8 0.18 10.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) HNF-1_N PF04814.13 OEU16929.1 - 1 10.0 7.3 0.1 13.2 1.1 2.5 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Dus PF01207.17 OEU16930.1 - 1.6e-20 73.4 0.0 1.9e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Phos_pyr_kin PF08543.12 OEU16931.1 - 3.6e-17 62.6 0.1 1.9e-16 60.2 0.0 1.9 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OEU16931.1 - 3.2e-09 36.5 0.0 3.6e-08 33.1 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase CPSF100_C PF13299.6 OEU16931.1 - 0.062 13.5 0.3 0.77 9.9 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RXT2_N PF08595.11 OEU16931.1 - 0.83 9.7 8.3 3.2 7.8 0.5 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 OEU16931.1 - 3.4 7.3 13.4 2.7 7.6 2.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 OEU16931.1 - 9.5 7.0 13.1 9 7.0 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BRO1 PF03097.18 OEU16932.1 - 2.8e-21 75.8 0.1 4.4e-21 75.1 0.1 1.3 1 1 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 OEU16932.1 - 0.003 16.7 0.2 0.0064 15.6 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5355) Armet PF10208.9 OEU16932.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding DUF3412 PF11892.8 OEU16932.1 - 0.088 12.9 0.3 19 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3412) tRNA_U5-meth_tr PF05958.11 OEU16934.1 - 1.2e-17 63.9 0.1 4.8e-08 32.4 0.0 2.8 2 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 OEU16934.1 - 2.5e-06 27.4 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 OEU16934.1 - 0.00021 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 OEU16934.1 - 0.0046 16.1 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OEU16934.1 - 0.0046 17.6 0.0 0.017 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OEU16934.1 - 0.0089 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OEU16934.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 OEU16934.1 - 0.015 16.0 0.0 0.12 13.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OEU16934.1 - 0.069 12.8 0.0 0.58 9.8 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical protein 95 Mpv17_PMP22 PF04117.12 OEU16935.1 - 1.9e-09 37.6 0.0 3.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Presenilin PF01080.17 OEU16935.1 - 0.061 12.1 6.1 0.13 11.0 6.1 1.5 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 OEU16935.1 - 0.068 14.1 10.3 1.4 10.0 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Helicase_RecD PF05127.14 OEU16935.1 - 0.072 12.9 1.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Helicase SRP9-21 PF05486.12 OEU16935.1 - 0.25 11.8 8.1 0.21 12.0 0.6 2.7 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) Maf1 PF09174.10 OEU16935.1 - 0.32 11.1 7.2 3 8.0 2.5 2.4 2 0 0 2 2 2 0 Maf1 regulator DUF1980 PF09323.10 OEU16935.1 - 0.43 10.5 8.1 2.2 8.2 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 OEU16935.1 - 2.2 7.8 19.0 0.9 9.1 3.1 2.6 2 0 0 2 2 2 0 Spt20 family dsDNA_bind PF01984.20 OEU16935.1 - 3.2 8.1 10.3 2.8 8.2 0.8 2.5 2 0 0 2 2 2 0 Double-stranded DNA-binding domain zf-C2H2_3rep PF18868.1 OEU16935.1 - 4.1 8.1 6.5 1.6 9.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats PAP2 PF01569.21 OEU16936.1 - 1.4e-13 50.8 1.3 1.4e-13 50.8 1.3 2.4 1 1 1 2 2 2 1 PAP2 superfamily CarS-like PF01864.17 OEU16936.1 - 0.02 14.9 5.8 7.8 6.5 0.0 3.2 2 1 1 3 3 3 0 CDP-archaeol synthase DUF4395 PF14340.6 OEU16936.1 - 0.055 13.8 0.3 0.055 13.8 0.3 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4395) VIT1 PF01988.19 OEU16936.1 - 0.1 12.4 3.1 0.16 11.8 0.2 2.5 2 1 0 2 2 2 0 VIT family Macoilin PF09726.9 OEU16936.1 - 0.51 8.8 7.6 0.73 8.3 7.6 1.2 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 OEU16936.1 - 3.5 7.3 9.9 7.1 6.3 9.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4400 PF14348.6 OEU16936.1 - 9.3 5.7 9.2 3.5 7.1 1.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4400) BCCT PF02028.17 OEU16937.1 - 6.8e-131 437.1 39.7 1.7e-107 359.8 29.6 2.3 2 0 0 2 2 2 2 BCCT, betaine/carnitine/choline family transporter PLAC8 PF04749.17 OEU16937.1 - 8.4e-07 29.9 0.0 8.4e-07 29.9 0.0 3.5 3 1 0 3 3 3 1 PLAC8 family CoA_binding_3 PF13727.6 OEU16937.1 - 1.2 9.1 6.2 0.52 10.3 1.4 2.7 2 0 0 2 2 2 0 CoA-binding domain Fic PF02661.18 OEU16938.1 - 0.017 16.0 0.4 0.058 14.3 0.4 1.9 1 0 0 1 1 1 0 Fic/DOC family DUF2126 PF09899.9 OEU16938.1 - 0.11 10.6 0.4 0.15 10.1 0.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4834 PF16118.5 OEU16938.1 - 0.14 13.2 6.0 0.23 12.4 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 OEU16938.1 - 0.22 11.3 3.5 0.13 12.0 1.7 1.5 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 OEU16938.1 - 0.28 9.9 3.1 0.34 9.6 3.1 1.2 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 OEU16938.1 - 2.7 7.6 13.8 7.9 6.1 6.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4175 PF13779.6 OEU16938.1 - 9.2 4.0 11.2 11 3.7 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Dak1 PF02733.17 OEU16939.1 - 2.5e-104 348.6 0.9 4.5e-104 347.7 0.9 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OEU16939.1 - 3e-42 144.4 4.5 8.1e-42 143.1 4.1 1.9 2 0 0 2 2 2 1 DAK2 domain Sec63 PF02889.16 OEU16940.1 - 1.8e-67 227.2 0.0 7.8e-67 225.1 0.0 1.9 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 OEU16940.1 - 4.4e-48 163.4 0.0 3.9e-26 91.9 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OEU16940.1 - 2.9e-23 82.7 0.0 3.5e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU16940.1 - 2.3e-13 50.4 0.0 2.2e-05 24.8 0.0 3.5 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.6 OEU16940.1 - 1.7e-08 35.0 0.0 0.0025 18.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OEU16940.1 - 4.9e-08 32.9 0.0 0.00014 21.6 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OEU16940.1 - 1.8e-05 25.0 3.9 0.54 10.5 0.6 4.4 2 2 0 2 2 2 2 AAA domain T2SSE PF00437.20 OEU16940.1 - 0.00075 18.6 0.0 0.11 11.6 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 OEU16940.1 - 0.0052 16.3 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 OEU16940.1 - 0.016 14.8 1.0 5.1 6.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 OEU16940.1 - 0.021 14.2 0.3 20 4.5 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein IstB_IS21 PF01695.17 OEU16940.1 - 0.094 12.4 0.0 0.96 9.2 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein SAM_PNT PF02198.16 OEU16942.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CagE_TrbE_VirB PF03135.14 OEU16942.1 - 0.13 12.4 0.1 1.1 9.4 0.0 2.1 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system Pyr_redox_2 PF07992.14 OEU16943.1 - 4.2e-33 114.8 0.0 5.5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU16943.1 - 1.5e-11 44.7 0.7 1.7e-09 38.1 0.8 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU16943.1 - 7.2 6.1 6.4 1.6 8.2 0.1 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase DUF2358 PF10184.9 OEU16944.1 - 1.3e-15 57.6 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Glyco_trans_1_3 PF13528.6 OEU16946.1 - 0.005 16.1 0.0 0.051 12.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_transf_28 PF03033.20 OEU16946.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain V-SNARE_C PF12352.8 OEU16947.1 - 6.3e-08 32.8 5.4 6.3e-08 32.8 5.4 1.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OEU16947.1 - 2.9e-05 23.9 0.1 5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Sec20 SNARE PF05739.19 OEU16947.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 SNARE domain Aha1_N PF09229.11 OEU16949.1 - 2.3e-24 86.2 1.5 2.3e-24 86.2 1.5 3.4 4 0 0 4 4 4 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 OEU16949.1 - 1.8e-09 37.0 0.0 0.00056 19.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU16949.1 - 4.1e-08 32.7 0.0 0.059 13.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU16949.1 - 1.4e-07 31.4 0.4 0.00038 20.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU16949.1 - 3.2e-07 30.1 11.7 0.0034 17.5 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU16949.1 - 2.5e-05 24.7 0.0 0.0066 17.2 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU16949.1 - 7.6e-05 22.7 0.0 0.16 12.0 0.0 2.8 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 OEU16949.1 - 0.00034 21.1 0.9 1.1 9.8 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU16949.1 - 0.001 18.7 0.1 0.46 10.2 0.0 3.5 2 2 2 4 4 4 2 TPR repeat TPR_12 PF13424.6 OEU16949.1 - 0.0012 19.1 0.1 1 9.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU16949.1 - 0.0037 17.9 0.0 0.012 16.2 0.0 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU16949.1 - 0.0083 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU16949.1 - 0.04 13.8 0.2 5.6 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU16949.1 - 0.077 13.7 2.6 1.1 10.0 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 OEU16950.1 - 2.6e-05 24.3 0.0 8.9e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OEU16950.1 - 0.049 12.9 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 OEU16950.1 - 0.064 12.3 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OEU16950.1 - 0.065 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.18 OEU16950.1 - 0.097 11.2 0.0 0.22 10.0 0.0 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor ExbD PF02472.16 OEU16950.1 - 0.12 12.5 0.2 0.37 11.0 0.2 1.8 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DAO PF01266.24 OEU16950.1 - 0.16 11.5 0.0 20 4.6 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase TPT PF03151.16 OEU16951.1 - 8.4e-100 333.9 15.0 1.1e-99 333.5 15.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU16951.1 - 1.8e-11 44.4 23.6 1.3e-05 25.4 7.6 2.6 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OEU16951.1 - 0.65 9.1 18.8 0.069 12.3 12.7 2.0 2 0 0 2 2 2 0 UAA transporter family NOT2_3_5 PF04153.18 OEU16952.1 - 5.2e-25 88.0 1.7 6.1e-25 87.8 1.7 1.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cupin_7 PF12973.7 OEU16953.1 - 0.097 12.6 0.3 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Pribosyltran PF00156.27 OEU16954.1 - 5.4e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 OEU16954.1 - 1.3e-07 31.9 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OEU16954.1 - 0.0003 20.7 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase DRMBL PF07522.14 OEU16954.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase SWI-SNF_Ssr4 PF08549.10 OEU16955.1 - 0.58 8.7 29.2 0.64 8.6 29.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SecE PF00584.20 OEU16956.1 - 2.4e-17 62.6 0.1 2.8e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 OEU16956.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) dCMP_cyt_deam_1 PF00383.23 OEU16957.1 - 6.1e-29 99.9 0.0 1e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OEU16957.1 - 5.9e-15 55.2 0.0 7.8e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OEU16957.1 - 0.0014 18.7 0.8 0.0047 17.0 0.1 1.9 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 OEU16957.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 OEU16957.1 - 0.0078 16.3 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 OEU16957.1 - 0.016 15.2 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase TMEM52 PF14979.6 OEU16958.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Transmembrane 52 Shisa PF13908.6 OEU16958.1 - 0.074 13.3 0.0 0.074 13.3 0.0 2.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator OPT PF03169.15 OEU16958.1 - 0.15 10.7 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF4442 PF14539.6 OEU16959.1 - 1.7e-32 112.3 0.1 1.9e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) DUF2500 PF10694.9 OEU16959.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) Glycos_transf_1 PF00534.20 OEU16960.1 - 3.4e-10 39.7 0.0 8.4e-10 38.4 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU16960.1 - 5.2e-08 33.4 0.0 1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OEU16960.1 - 0.012 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 F-box-like PF12937.7 OEU16961.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like SLATT_fungal PF18142.1 OEU16961.1 - 0.16 11.9 1.1 0.25 11.4 1.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF1475 PF07343.11 OEU16962.1 - 0.0074 16.1 2.3 0.01 15.7 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1475) Mid2 PF04478.12 OEU16962.1 - 0.044 13.6 1.7 0.054 13.3 1.7 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4711 PF15829.5 OEU16962.1 - 0.052 13.5 1.5 0.066 13.1 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Orf78 PF06024.12 OEU16962.1 - 0.057 13.7 0.1 0.097 13.0 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 OEU16962.1 - 0.076 12.9 1.7 0.11 12.5 1.7 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2116 PF09889.9 OEU16962.1 - 0.14 12.1 0.7 0.28 11.2 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TPT PF03151.16 OEU16963.1 - 4.7e-31 108.2 26.7 5.4e-31 108.0 26.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU16963.1 - 2.6e-07 30.9 29.8 0.0018 18.4 11.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family Synaptobrevin PF00957.21 OEU16964.1 - 2.7e-30 104.0 0.3 4.3e-30 103.4 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OEU16964.1 - 4.9e-23 81.0 0.2 8.4e-23 80.2 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nudix_hydro PF18290.1 OEU16964.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Nudix hydrolase domain UL2 PF08196.11 OEU16965.1 - 0.44 10.5 6.8 3.8 7.5 6.8 2.1 1 1 0 1 1 1 0 UL2 protein BTB_2 PF02214.22 OEU16966.1 - 5.3e-16 58.8 0.0 1.3e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU16966.1 - 8.8e-06 25.8 0.0 5.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain PsbP PF01789.16 OEU16967.1 - 0.0066 16.6 0.8 0.037 14.1 0.8 2.2 1 1 0 1 1 1 1 PsbP SpoOE-like PF09388.10 OEU16968.1 - 0.09 12.7 0.7 1.4 8.9 0.2 2.9 2 1 0 2 2 2 0 Spo0E like sporulation regulatory protein DUF3140 PF11338.8 OEU16968.1 - 0.14 12.6 2.6 0.32 11.5 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) GREB1 PF15782.5 OEU16968.1 - 1.1 6.3 11.9 1.3 6.0 11.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 OEU16968.1 - 9.4 4.4 13.0 12 4.0 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_33 PF13671.6 OEU16969.1 - 1.7e-15 57.5 0.1 4.7e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU16969.1 - 0.00014 22.4 0.2 0.00065 20.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 OEU16969.1 - 0.0012 18.2 0.0 0.0023 17.2 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 OEU16969.1 - 0.0014 18.6 0.2 0.0043 17.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 OEU16969.1 - 0.0028 17.0 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 OEU16969.1 - 0.0031 18.0 0.2 0.0056 17.2 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OEU16969.1 - 0.0045 17.3 0.7 0.011 16.0 0.0 2.1 3 0 0 3 3 3 1 AAA domain RRP7 PF12923.7 OEU16969.1 - 0.006 16.7 0.9 0.013 15.6 0.9 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain 6PF2K PF01591.18 OEU16969.1 - 0.0097 15.2 0.0 0.029 13.7 0.0 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 OEU16969.1 - 0.013 15.4 0.3 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 OEU16969.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 OEU16969.1 - 0.023 15.1 0.1 0.061 13.8 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU16969.1 - 0.024 15.0 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 OEU16969.1 - 0.025 15.0 0.2 0.32 11.4 0.2 2.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU16969.1 - 0.033 14.6 0.7 0.096 13.1 0.1 2.1 2 1 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OEU16969.1 - 0.054 13.0 0.3 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 OEU16969.1 - 0.1 12.3 0.4 7.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase CPT PF07931.12 OEU16969.1 - 0.22 11.3 0.5 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein CAF20 PF17052.5 OEU16969.1 - 0.26 11.5 4.5 0.074 13.2 1.3 1.8 2 0 0 2 2 2 0 Cap associated factor Cpn60_TCP1 PF00118.24 OEU16972.1 - 3.5e-92 309.6 15.8 1.6e-91 307.4 15.8 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 OEU16973.1 - 3.3e-33 114.9 0.0 6.8e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU16973.1 - 9.7e-10 38.1 0.1 2.8e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OEU16973.1 - 1.1e-07 31.9 0.6 8e-07 29.1 0.6 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU16973.1 - 6.9e-05 22.6 0.1 0.0013 18.5 0.1 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OEU16973.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU16973.1 - 0.00017 22.0 0.5 0.015 15.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OEU16973.1 - 0.00073 19.8 1.1 0.011 16.0 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 OEU16973.1 - 0.00087 19.4 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OEU16973.1 - 0.00099 19.3 0.1 0.0028 17.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU16973.1 - 0.0017 17.7 0.0 0.0043 16.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 OEU16973.1 - 0.0035 17.1 0.1 0.02 14.6 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 OEU16973.1 - 0.0051 16.2 0.1 0.015 14.6 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OEU16973.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU16973.1 - 0.007 16.9 0.9 0.035 14.7 0.0 2.6 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OEU16973.1 - 0.0086 16.4 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 OEU16973.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Viral_helicase1 PF01443.18 OEU16973.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 OEU16973.1 - 0.015 15.0 0.2 0.045 13.5 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OEU16973.1 - 0.02 14.8 0.1 0.085 12.8 0.1 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OEU16973.1 - 0.023 14.6 0.0 0.52 10.2 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.27 OEU16973.1 - 0.033 14.7 0.9 0.085 13.4 0.8 2.0 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OEU16973.1 - 0.035 13.7 1.4 0.18 11.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 OEU16973.1 - 0.041 14.3 0.0 0.041 14.3 0.0 2.7 3 1 0 4 4 3 0 AAA domain AAA_28 PF13521.6 OEU16973.1 - 0.068 13.4 0.2 0.23 11.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain MDD_C PF18376.1 OEU16973.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain AAA_11 PF13086.6 OEU16973.1 - 4.8 6.9 7.7 35 4.1 7.7 2.4 1 1 0 1 1 1 0 AAA domain Sedlin_N PF04628.13 OEU16974.1 - 7.8e-21 74.6 0.4 3e-20 72.7 0.1 1.9 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OEU16974.1 - 0.0089 16.0 0.3 0.11 12.4 0.3 2.3 1 1 0 1 1 1 1 Sybindin-like family Metal_resist PF13801.6 OEU16975.1 - 0.00066 19.9 2.5 0.0078 16.4 0.0 3.1 3 1 0 3 3 3 1 Heavy-metal resistance Erp_C PF06780.11 OEU16975.1 - 1.9 8.5 13.2 0.13 12.3 0.7 3.2 2 1 1 3 3 3 0 Erp protein C-terminus T3SSipB PF16535.5 OEU16975.1 - 1.9 8.9 9.2 3.7 8.0 1.4 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB IATP PF04568.12 OEU16975.1 - 4.6 7.7 15.9 1.4 9.4 0.4 3.7 3 1 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP FliJ PF02050.16 OEU16975.1 - 9.6 6.5 27.4 3.3 8.0 9.1 3.5 2 1 1 3 3 3 0 Flagellar FliJ protein SAP PF02037.27 OEU16976.1 - 6.4e-06 25.8 1.2 1.8e-05 24.4 0.3 2.0 2 0 0 2 2 2 1 SAP domain TPR_2 PF07719.17 OEU16976.1 - 0.0074 16.3 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU16976.1 - 0.11 12.4 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 OEU16977.1 - 7.5e-36 123.9 0.2 5.9e-34 117.7 0.0 3.0 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.12 OEU16977.1 - 4e-07 30.7 0.0 2.7e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU16977.1 - 8.3e-07 28.9 0.0 4.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU16977.1 - 2.5e-06 28.1 0.1 0.00072 20.2 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU16977.1 - 0.00014 22.5 0.1 0.34 11.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.6 OEU16977.1 - 0.13 12.2 0.0 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain CENP-B_dimeris PF09026.10 OEU16977.1 - 0.14 12.5 10.3 2.7 8.4 0.6 3.2 4 0 0 4 4 4 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OEU16977.1 - 4.7 7.7 11.5 12 6.4 1.2 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 OEU16979.1 - 2.2e-31 109.2 0.0 2.5e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16979.1 - 2.7e-29 102.3 0.0 2.9e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU16979.1 - 0.0091 15.9 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.21 OEU16980.1 - 0.047 13.4 5.1 0.074 12.8 5.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 NPR1_interact PF15699.5 OEU16980.1 - 0.38 11.4 7.6 1.7 9.3 1.7 3.0 2 1 0 2 2 2 0 NPR1 interacting SUIM_assoc PF16619.5 OEU16980.1 - 3.1 7.9 16.3 5.4 7.2 0.8 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GRIP PF01465.20 OEU16981.1 - 4.3e-12 45.8 0.0 8.3e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 GRIP domain TFIIA PF03153.13 OEU16982.1 - 0.015 15.3 0.3 0.02 14.9 0.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LSM PF01423.22 OEU16984.1 - 5.5e-10 38.8 1.8 2.4e-09 36.8 1.8 2.1 1 1 0 1 1 1 1 LSM domain TANGO2 PF05742.12 OEU16986.1 - 1.2e-27 97.6 0.1 1.8e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Methyltransf_12 PF08242.12 OEU16986.1 - 1.2 9.9 3.5 4.9 8.0 0.5 2.3 2 0 0 2 2 2 0 Methyltransferase domain TK PF00265.18 OEU16988.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase MTBP_C PF14920.6 OEU16989.1 - 0.088 12.5 2.0 0.12 12.1 2.0 1.1 1 0 0 1 1 1 0 MDM2-binding Hydrolase_4 PF12146.8 OEU16991.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 OEU16993.1 - 2.6e-76 256.5 0.0 5.4e-76 255.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU16993.1 - 2.6e-35 122.0 0.0 4.3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 OEU16993.1 - 3.6e-10 39.5 0.8 9.6e-06 25.4 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 OEU16993.1 - 3e-09 37.2 6.6 0.00033 21.1 4.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU16993.1 - 8.1e-09 34.4 2.1 5.1e-06 25.6 0.4 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU16993.1 - 1.7e-08 33.7 8.0 0.00035 20.3 0.3 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OEU16993.1 - 1.3e-06 27.6 2.4 0.00014 21.2 0.2 2.9 2 0 0 2 2 2 2 EF hand Kinase-like PF14531.6 OEU16993.1 - 2.4e-06 27.1 0.0 6.4e-05 22.4 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OEU16993.1 - 7.9e-06 25.4 0.1 1.9e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU16993.1 - 0.001 19.1 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3439 PF11921.8 OEU16994.1 - 0.11 12.5 3.3 0.16 12.0 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF87 PF01935.17 OEU16995.1 - 0.0008 19.6 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain DUF4746 PF15928.5 OEU16997.1 - 0.011 15.2 10.4 0.017 14.6 6.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF3381 PF11861.8 OEU16997.1 - 0.83 9.4 14.9 4 7.2 11.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Lin-8 PF03353.15 OEU16997.1 - 4.1 6.9 11.6 4.7 6.7 5.2 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Na_trans_assoc PF06512.13 OEU16997.1 - 4.6 7.5 11.3 0.9 9.8 2.4 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated Nop14 PF04147.12 OEU16997.1 - 9.1 4.4 16.4 0.17 10.0 9.6 1.5 2 0 0 2 2 2 0 Nop14-like family NnrU PF07298.11 OEU17000.1 - 9.8e-11 41.6 0.4 6.4e-09 35.6 0.0 2.8 2 1 0 2 2 2 1 NnrU protein FAD_binding_4 PF01565.23 OEU17001.1 - 5.9e-08 32.5 0.6 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 OEU17001.1 - 0.034 14.2 0.0 0.034 14.2 0.0 1.9 2 0 0 2 2 2 0 Berberine and berberine like DUF3439 PF11921.8 OEU17001.1 - 0.037 14.0 1.1 0.28 11.2 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Pico_P1A PF02226.16 OEU17001.1 - 0.11 12.5 0.9 0.33 11.0 0.1 2.2 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) CX9C PF16860.5 OEU17001.1 - 3 7.9 4.6 2.1 8.4 2.1 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_8 PF06259.12 OEU17002.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Palm_thioest PF02089.15 OEU17002.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase NOA36 PF06524.12 OEU17003.1 - 0.81 9.0 5.9 2.4 7.4 0.6 2.5 2 0 0 2 2 2 0 NOA36 protein DUF3439 PF11921.8 OEU17003.1 - 4.8 7.2 11.2 0.31 11.0 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) adh_short_C2 PF13561.6 OEU17004.1 - 2.2e-15 56.9 0.0 1.4e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU17004.1 - 4.3e-15 55.7 0.0 7.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU17004.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OEU17004.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF5387 PF17361.2 OEU17006.1 - 0.028 14.1 0.8 0.23 11.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5387) CDC45 PF02724.14 OEU17007.1 - 2 6.6 16.8 2.2 6.5 16.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OEU17007.1 - 4.3 6.0 4.9 4.8 5.8 4.9 1.1 1 0 0 1 1 1 0 Presenilin DAGK_prokar PF01219.19 OEU17008.1 - 0.095 12.5 0.2 0.71 9.7 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase PIEZO PF15917.5 OEU17008.1 - 0.11 12.0 5.9 0.17 11.4 5.9 1.2 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 OEU17008.1 - 0.45 9.2 1.9 0.81 8.4 1.9 1.3 1 0 0 1 1 1 0 Presenilin DUF536 PF04394.14 OEU17009.1 - 0.058 13.3 6.4 0.14 12.1 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF536 DZR PF12773.7 OEU17009.1 - 0.073 13.1 1.5 0.16 12.0 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon PNPase_C PF12111.8 OEU17009.1 - 0.11 11.9 0.8 0.24 10.9 0.8 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal MerR-DNA-bind PF09278.11 OEU17009.1 - 1.1 9.9 4.9 1.3 9.6 3.4 1.9 2 0 0 2 2 2 0 MerR, DNA binding DZR PF12773.7 OEU17011.1 - 0.12 12.4 1.8 0.28 11.2 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU17011.1 - 0.12 12.1 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain PNPase_C PF12111.8 OEU17011.1 - 0.15 11.5 2.0 0.24 10.9 0.8 1.9 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal DDE_Tnp_1 PF01609.21 OEU17012.1 - 0.017 14.8 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain rve PF00665.26 OEU17012.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain FAM199X PF15814.5 OEU17013.1 - 2.5 7.1 5.5 0.82 8.7 3.0 1.4 2 0 0 2 2 2 0 Protein family FAM199X SR-25 PF10500.9 OEU17013.1 - 5.9 6.4 15.1 0.37 10.4 10.1 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.19 OEU17016.1 - 9.7e-11 41.5 0.1 1.2e-06 28.0 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 OEU17016.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 OEU17016.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 OEU17016.1 - 0.15 11.1 0.1 0.32 10.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Helicase_C PF00271.31 OEU17017.1 - 3.9e-15 56.2 0.0 5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1 PF00133.22 OEU17018.1 - 3.2e-178 593.7 0.0 6.3e-177 589.5 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OEU17018.1 - 4.6e-37 127.3 0.0 8.2e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 OEU17018.1 - 3.2e-11 43.1 0.1 1.3e-07 31.3 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 OEU17018.1 - 1.3e-10 40.6 0.0 1.1e-06 27.7 0.1 3.6 3 1 0 3 3 3 2 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 OEU17018.1 - 0.00019 21.7 0.1 0.00019 21.7 0.1 2.4 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 OEU17018.1 - 0.0012 18.2 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Jag_N PF14804.6 OEU17018.1 - 0.012 15.9 0.4 0.038 14.3 0.4 1.9 1 0 0 1 1 1 0 Jag N-terminus tRNA-synt_1b PF00579.25 OEU17018.1 - 0.052 12.9 0.2 3.3 6.9 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Ion_trans_N PF08412.10 OEU17018.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal HCV_NS5a_1a PF08300.13 OEU17018.1 - 0.081 13.1 0.1 10 6.3 0.0 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Acatn PF13000.7 OEU17019.1 - 1.2e-85 288.1 0.1 3.5e-69 233.7 0.0 2.8 1 1 1 3 3 3 2 Acetyl-coenzyme A transporter 1 Fumarate_red_D PF02313.17 OEU17019.1 - 0.15 12.2 2.8 0.86 9.7 0.2 2.7 2 0 0 2 2 2 0 Fumarate reductase subunit D DNA_pol_A_exo1 PF01612.20 OEU17020.1 - 1.6e-11 44.3 0.0 4.2e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Desulfoferrod_N PF06397.12 OEU17020.1 - 0.12 12.0 0.5 0.28 10.8 0.5 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Peptidase_S46 PF10459.9 OEU17021.1 - 7.3e-62 210.0 0.2 1.4e-61 209.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase S46 Trypsin_2 PF13365.6 OEU17021.1 - 0.0018 19.2 0.0 0.004 18.1 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF4252 PF14060.6 OEU17021.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Peptidase_S46 PF10459.9 OEU17022.1 - 3.3e-63 214.5 0.1 1.5e-62 212.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase S46 Trypsin_2 PF13365.6 OEU17022.1 - 0.0013 19.7 0.0 0.0057 17.6 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain EamA PF00892.20 OEU17023.1 - 7e-19 68.4 27.0 2.7e-12 47.0 12.9 3.0 2 2 0 2 2 2 2 EamA-like transporter family Drf_GBD PF06371.13 OEU17023.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain TPT PF03151.16 OEU17023.1 - 0.043 13.2 9.4 0.041 13.2 0.8 2.7 2 1 1 3 3 3 0 Triose-phosphate Transporter family UPF0139 PF03669.13 OEU17024.1 - 0.96 9.4 10.9 52 3.8 0.1 5.0 2 1 4 6 6 6 0 Uncharacterised protein family (UPF0139) PPR_2 PF13041.6 OEU17025.1 - 2.3e-45 152.6 0.8 2.2e-06 27.8 0.0 11.1 9 3 2 11 11 11 8 PPR repeat family PPR_1 PF12854.7 OEU17025.1 - 8.8e-36 121.3 2.4 4.5e-07 29.5 0.0 14.1 16 0 0 16 16 16 6 PPR repeat PPR_3 PF13812.6 OEU17025.1 - 3.4e-27 94.3 0.0 0.00014 21.8 0.0 9.3 9 1 0 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.20 OEU17025.1 - 5.8e-20 70.1 33.3 6.6e-06 26.0 0.0 13.0 17 2 0 17 17 17 5 PPR repeat PPR_long PF17177.4 OEU17025.1 - 1.3e-15 57.3 3.2 2.6e-06 27.0 0.1 6.5 3 1 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP SAP PF02037.27 OEU17031.1 - 0.004 16.9 0.1 0.072 12.9 0.1 2.6 3 0 0 3 3 3 1 SAP domain CDC45 PF02724.14 OEU17031.1 - 0.34 9.1 14.0 0.49 8.6 14.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OEU17031.1 - 6.5 5.5 21.7 10 4.9 21.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 OEU17031.1 - 8.2 3.4 16.6 9 3.3 16.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Serinc PF03348.15 OEU17033.1 - 0.22 10.4 7.6 0.29 10.0 7.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 OEU17033.1 - 0.77 9.5 18.7 0.9 9.3 18.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 OEU17033.1 - 0.9 8.4 11.4 1 8.2 11.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NOA36 PF06524.12 OEU17033.1 - 1.6 8.0 16.5 2 7.6 16.5 1.1 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 OEU17033.1 - 2.5 6.0 19.0 3 5.7 19.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 OEU17033.1 - 2.6 8.0 6.8 3.4 7.7 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3959 PF13105.6 OEU17033.1 - 3.8 7.0 7.0 5.5 6.4 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) NPR3 PF03666.13 OEU17033.1 - 6.9 5.3 15.7 8.2 5.1 15.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 OEU17034.1 - 3.4e-05 23.5 0.0 7.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU17034.1 - 0.01 15.4 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Mei5_like PF17021.5 OEU17035.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.9 2 1 1 3 3 3 0 Putative double-strand recombination repair-like Endotoxin_N PF03945.14 OEU17035.1 - 0.065 12.9 1.3 0.14 11.9 0.0 2.1 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain HA PF03457.14 OEU17036.1 - 3.3e-25 88.2 6.0 4.2e-14 52.6 0.1 2.9 3 0 0 3 3 3 2 Helicase associated domain CDC45 PF02724.14 OEU17036.1 - 0.28 9.4 12.2 0.35 9.1 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OEU17036.1 - 2 7.1 11.2 2.5 6.8 11.2 1.3 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 OEU17036.1 - 4.1 7.9 12.4 5 7.6 12.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein LMBR1 PF04791.16 OEU17036.1 - 4.2 6.1 9.8 6 5.6 9.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CLN3 PF02487.17 OEU17036.1 - 6.9 5.6 5.2 9 5.2 5.2 1.3 1 0 0 1 1 1 0 CLN3 protein Sporozoite_P67 PF05642.11 OEU17037.1 - 0.053 11.6 7.2 0.057 11.5 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 OEU17037.1 - 0.077 11.2 4.0 0.088 11.0 4.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MS_channel PF00924.18 OEU17038.1 - 1.2e-25 90.3 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel zf-RING_2 PF13639.6 OEU17040.1 - 1.2e-05 25.5 1.5 1.2e-05 25.5 1.5 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OEU17040.1 - 4.6e-05 23.1 4.3 0.00013 21.6 4.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 OEU17040.1 - 8.2e-05 22.7 1.3 8.2e-05 22.7 1.3 1.8 2 0 0 2 2 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 OEU17040.1 - 0.0014 18.9 1.6 0.0014 18.9 1.6 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU17040.1 - 0.0018 18.1 1.5 0.0018 18.1 1.5 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU17040.1 - 0.0033 17.4 0.4 0.0033 17.4 0.4 2.0 2 0 0 2 2 1 1 RING-type zinc-finger RINGv PF12906.7 OEU17040.1 - 0.012 15.7 2.2 0.032 14.3 2.2 1.7 1 0 0 1 1 1 0 RING-variant domain Vpu PF00558.19 OEU17040.1 - 0.019 14.7 3.2 0.055 13.2 0.8 2.6 1 1 0 2 2 2 0 Vpu protein DUF2572 PF10833.8 OEU17040.1 - 0.038 13.7 1.1 0.071 12.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Zn_ribbon_17 PF17120.5 OEU17040.1 - 0.039 13.6 1.2 0.039 13.6 1.2 1.8 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OEU17040.1 - 0.083 12.9 1.8 0.25 11.4 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3483 PF11982.8 OEU17041.1 - 0.012 15.3 1.1 0.018 14.7 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) HATPase_c PF02518.26 OEU17042.1 - 1.4e-05 25.5 0.1 3.2e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OEU17042.1 - 0.00011 22.1 0.8 0.00034 20.6 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HWE_HK PF07536.14 OEU17042.1 - 0.17 12.6 3.7 12 6.7 0.2 3.7 3 0 0 3 3 3 0 HWE histidine kinase DUF3037 PF11236.8 OEU17042.1 - 0.68 10.4 10.1 0.31 11.5 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) PEP-utilizers_C PF02896.18 OEU17044.1 - 1.3e-95 319.9 0.0 2e-95 319.3 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 OEU17044.1 - 1.1e-52 179.4 0.0 1.4e-39 136.3 0.0 3.1 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OEU17044.1 - 8.4e-26 89.5 0.1 2.2e-25 88.2 0.1 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Cupin_3 PF05899.12 OEU17044.1 - 0.17 11.6 0.1 0.45 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF2070 PF09843.9 OEU17045.1 - 0.78 7.9 6.8 1.1 7.5 6.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FA_desaturase PF00487.24 OEU17045.1 - 3.8 7.3 5.8 1.7 8.4 3.1 1.7 1 1 1 2 2 2 0 Fatty acid desaturase RasGAP_C PF03836.15 OEU17046.1 - 0.21 11.7 4.4 0.33 11.1 4.4 1.2 1 0 0 1 1 1 0 RasGAP C-terminus TatD_DNase PF01026.21 OEU17048.1 - 2.6e-16 59.8 0.0 6.3e-10 38.9 0.0 2.4 1 1 1 2 2 2 2 TatD related DNase Nucleotid_trans PF03407.16 OEU17049.1 - 7.1e-31 107.8 2.2 9.2e-31 107.5 2.2 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Amidase PF01425.21 OEU17050.1 - 1.2e-76 258.5 0.5 1.2e-72 245.3 0.0 3.4 3 1 0 3 3 3 3 Amidase DUF2732 PF10809.8 OEU17050.1 - 0.017 15.0 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) F-box-like PF12937.7 OEU17052.1 - 0.0096 15.8 0.3 0.019 14.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 OEU17052.1 - 0.072 13.6 4.0 0.16 12.5 4.0 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TPR_MLP1_2 PF07926.12 OEU17052.1 - 0.17 11.9 1.2 0.32 11.1 1.2 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GYF PF02213.16 OEU17054.1 - 1.3e-10 40.8 0.3 3e-10 39.6 0.3 1.6 1 0 0 1 1 1 1 GYF domain Wbp11 PF09429.10 OEU17054.1 - 8.4e-09 35.7 10.9 8.4e-09 35.7 10.9 4.4 5 0 0 5 5 5 1 WW domain binding protein 11 GYF_2 PF14237.6 OEU17054.1 - 3.9e-06 26.6 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 GYF domain 2 NpwBP PF12622.7 OEU17054.1 - 0.0024 18.6 0.1 0.0024 18.6 0.1 5.4 4 1 0 4 4 4 1 mRNA biogenesis factor zf-MYND PF01753.18 OEU17055.1 - 2.2e-08 34.0 18.7 5.6e-08 32.7 18.7 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU17055.1 - 0.034 14.2 5.7 0.8 9.8 7.5 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DnaJ PF00226.31 OEU17056.1 - 2.5e-07 30.7 0.1 8.1e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Glyco_trans_2_3 PF13632.6 OEU17057.1 - 1.5e-15 57.6 0.1 1.5e-15 57.6 0.1 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 COX4_pro_2 PF07835.12 OEU17057.1 - 0.82 9.8 5.6 7.4 6.8 4.7 2.9 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF3663 PF12404.8 OEU17058.1 - 0.076 13.1 0.2 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Peptidase YL1 PF05764.13 OEU17058.1 - 0.086 12.9 3.7 0.6 10.2 0.3 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Ldh_2 PF02615.14 OEU17060.1 - 7.5e-84 281.7 0.2 1.4e-83 280.8 0.2 1.4 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase Thioredoxin PF00085.20 OEU17061.1 - 9.4e-20 70.5 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU17061.1 - 5.6e-06 26.8 0.0 2.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU17061.1 - 8e-05 22.4 0.0 9.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OEU17061.1 - 0.0011 18.7 0.1 0.0022 17.7 0.1 1.5 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 OEU17061.1 - 0.0012 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OEU17061.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 OEU17061.1 - 0.0067 16.4 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE GSHPx PF00255.19 OEU17062.1 - 1.1e-14 54.0 0.1 8.3e-14 51.1 0.1 2.2 1 1 0 1 1 1 1 Glutathione peroxidase Phosphonate-bd PF12974.7 OEU17062.1 - 0.012 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein GSHPx PF00255.19 OEU17063.1 - 7.6e-15 54.4 0.1 6.4e-14 51.4 0.1 2.2 1 1 0 1 1 1 1 Glutathione peroxidase Sod_Fe_C PF02777.18 OEU17064.1 - 5.5e-39 132.4 0.1 1.1e-38 131.5 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OEU17064.1 - 7.1e-26 90.5 0.9 1.2e-25 89.7 0.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 OEU17065.1 - 4.1e-39 132.9 0.1 8.2e-39 131.9 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OEU17065.1 - 9e-26 90.2 1.7 9.5e-26 90.1 0.3 1.8 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain polyprenyl_synt PF00348.17 OEU17066.1 - 3.5e-59 199.9 0.0 5.4e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 OEU17066.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.7 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Seadorna_VP7 PF07387.11 OEU17066.1 - 0.027 13.5 0.1 0.058 12.4 0.1 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Suc_Fer-like PF06999.12 OEU17066.1 - 0.094 12.6 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Sucrase/ferredoxin-like BPL_LplA_LipB PF03099.19 OEU17067.1 - 8.9e-09 35.3 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB PF03099.19 OEU17068.1 - 6.3e-09 35.8 0.0 3.4e-08 33.4 0.0 2.1 3 0 0 3 3 3 1 Biotin/lipoate A/B protein ligase family DUF4611 PF15387.6 OEU17068.1 - 0.88 9.8 6.3 2.8 8.2 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SHMT PF00464.19 OEU17069.1 - 1.1e-199 663.1 0.0 1.5e-199 662.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OEU17069.1 - 0.021 14.1 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OEU17070.1 - 5.8e-65 219.8 0.0 7.3e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OEU17070.1 - 0.0024 16.9 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OEU17070.1 - 0.0037 16.6 0.0 0.0079 15.5 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 OEU17070.1 - 0.009 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.21 OEU17070.1 - 0.026 13.2 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III TAP35_44 PF07265.11 OEU17070.1 - 0.082 12.9 1.7 0.18 11.8 1.7 1.6 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Glyoxalase PF00903.25 OEU17071.1 - 1.3e-06 28.7 0.0 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 OEU17071.1 - 4.7e-06 26.8 0.2 0.00045 20.4 0.0 3.4 3 1 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 OEU17071.1 - 0.0006 20.1 0.0 0.014 15.7 0.0 2.7 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OEU17071.1 - 0.008 16.3 0.2 0.44 10.6 0.1 2.9 2 1 0 2 2 2 1 Glyoxalase-like domain Kinase-PPPase PF03618.14 OEU17072.1 - 1.4e-74 251.1 0.0 2e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Kinase/pyrophosphorylase AAA_18 PF13238.6 OEU17072.1 - 3 8.4 5.5 10 6.7 0.1 3.2 2 1 1 3 3 3 0 AAA domain NUDIX PF00293.28 OEU17073.1 - 4.7e-17 62.2 0.4 1.6e-16 60.6 0.4 1.8 1 1 0 1 1 1 1 NUDIX domain CYLD_phos_site PF16607.5 OEU17073.1 - 0.11 12.3 0.5 0.2 11.5 0.5 1.3 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured p450 PF00067.22 OEU17074.1 - 2.1e-76 257.6 0.0 5.5e-76 256.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ldh_1_C PF02866.18 OEU17075.1 - 1.3e-43 148.8 0.0 2.5e-43 147.9 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OEU17075.1 - 8.3e-41 139.4 0.0 1.8e-40 138.3 0.0 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OEU17075.1 - 0.029 13.7 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 OEU17075.1 - 0.047 12.7 0.0 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cellulase PF00150.18 OEU17076.1 - 1.7e-09 37.6 1.8 4.7e-09 36.1 1.8 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 OEU17076.1 - 0.049 14.3 0.1 0.13 12.9 0.1 1.8 1 0 0 1 1 1 0 X8 domain Glucan_synthase PF02364.15 OEU17077.1 - 7.2e-189 629.8 14.5 3.3e-166 554.8 11.9 3.1 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OEU17077.1 - 1.7e-19 70.5 4.3 7.2e-19 68.4 4.3 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-met2 PF12907.7 OEU17078.1 - 2.1e-11 43.7 0.2 3.6e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding FYDLN_acid PF09538.10 OEU17078.1 - 0.049 14.3 1.9 0.086 13.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SKN1 PF03935.15 OEU17079.1 - 8.4e-62 209.2 8.6 1.1e-47 162.7 5.0 4.4 4 1 0 4 4 4 3 Beta-glucan synthesis-associated protein (SKN1) EGF_2 PF07974.13 OEU17079.1 - 0.0023 18.3 2.0 0.0023 18.3 2.0 3.2 3 0 0 3 3 3 1 EGF-like domain MutS_V PF00488.21 OEU17080.1 - 2.6e-47 161.3 1.0 3.5e-47 160.9 0.2 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OEU17080.1 - 2.4e-20 73.6 2.2 4.2e-20 72.8 0.9 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OEU17080.1 - 6e-07 29.7 0.2 1.6e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 MutS family domain IV AAA_22 PF13401.6 OEU17080.1 - 0.096 13.0 0.6 2.1 8.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain Sm_multidrug_ex PF06695.11 OEU17081.1 - 5.6e-29 101.2 5.3 1.3e-28 100.0 5.3 1.7 1 0 0 1 1 1 1 Putative small multi-drug export protein NAD_binding_1 PF00175.21 OEU17081.1 - 5.8e-27 94.5 0.0 1.3e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU17081.1 - 0.077 13.4 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF997 PF06196.12 OEU17081.1 - 0.44 10.6 2.6 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Trp_oprn_chp PF09534.10 OEU17081.1 - 0.76 9.5 7.4 9.6 6.0 0.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) His_Phos_1 PF00300.22 OEU17082.1 - 7.9e-35 120.3 0.0 5e-29 101.4 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 OEU17083.1 - 2.5e-27 95.8 0.0 6.6e-21 74.9 0.1 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) SMN PF06003.12 OEU17083.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Fcf2 PF08698.11 OEU17083.1 - 0.26 11.7 4.2 0.092 13.1 0.5 2.2 2 1 0 2 2 2 0 Fcf2 pre-rRNA processing His_Phos_1 PF00300.22 OEU17084.1 - 3.8e-35 121.4 0.0 7.6e-34 117.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EF-hand_6 PF13405.6 OEU17084.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 OEU17084.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 OEU17084.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 EF hand PGI PF00342.19 OEU17085.1 - 4e-189 629.3 0.0 5.5e-189 628.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.32 OEU17086.1 - 1.7e-08 34.9 0.4 0.018 15.9 0.2 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU17086.1 - 0.022 15.1 0.0 9.8 6.6 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GlcNAc PF11397.8 OEU17087.1 - 2.2e-64 218.1 1.1 4.6e-51 174.3 0.3 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 OEU17087.1 - 1e-15 58.4 0.0 2.9e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU17087.1 - 5.1e-07 30.3 0.0 1.7e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_10 PF00852.19 OEU17088.1 - 3.7e-37 127.8 0.7 7.2e-37 126.8 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term FAD_binding_3 PF01494.19 OEU17089.1 - 3.1e-08 33.3 0.0 1.8e-07 30.7 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain CENP-B_dimeris PF09026.10 OEU17089.1 - 0.015 15.7 1.8 0.39 11.1 0.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PASTA PF03793.19 OEU17089.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 PASTA domain HSA PF07529.13 OEU17090.1 - 4.7e-09 36.4 0.1 1.3e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 HSA ResIII PF04851.15 OEU17090.1 - 0.025 14.6 0.2 0.25 11.3 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Folate_carrier PF01770.18 OEU17091.1 - 0.0088 14.8 4.3 0.016 14.0 3.4 1.7 2 0 0 2 2 2 1 Reduced folate carrier Peptidase_S3 PF00944.19 OEU17091.1 - 0.087 12.6 0.2 7.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Alphavirus core protein Presenilin PF01080.17 OEU17091.1 - 3.5 6.3 6.2 7.6 5.2 6.2 1.6 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 OEU17091.1 - 4.4 7.3 23.4 9.8 6.2 5.9 3.3 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF4834 PF16118.5 OEU17091.1 - 5.7 8.0 15.9 1.1 10.3 5.4 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 OEU17093.1 - 8.5e-53 179.4 0.0 9.9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17093.1 - 1.3e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU17093.1 - 0.00026 20.4 0.2 0.0004 19.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OEU17093.1 - 0.0022 17.6 0.7 0.012 15.2 0.1 2.0 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 OEU17093.1 - 0.0055 16.1 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like GP44 PF17510.2 OEU17093.1 - 0.037 14.3 0.1 0.077 13.3 0.1 1.5 1 0 0 1 1 1 0 Gene product 44 APH PF01636.23 OEU17093.1 - 0.06 13.3 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-RanBP PF00641.18 OEU17094.1 - 0.12 11.7 8.0 0.33 10.3 8.0 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others HA2 PF04408.23 OEU17095.1 - 9.4e-18 64.5 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OEU17095.1 - 3.9e-16 59.2 0.0 1e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OEU17095.1 - 1e-13 51.6 0.0 2.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU17095.1 - 9.7e-05 22.2 0.2 0.00033 20.5 0.1 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase adh_short PF00106.25 OEU17096.1 - 2.5e-19 69.5 1.8 7.7e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17096.1 - 2.4e-06 27.3 0.2 0.0047 16.5 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OEU17096.1 - 0.017 14.6 0.3 0.038 13.4 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TFIIE-A_C PF11521.8 OEU17096.1 - 0.17 12.2 5.0 1.9 8.9 2.9 2.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha PDEase_I PF00233.19 OEU17097.1 - 1.6e-70 237.6 0.0 1.8e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2264 PF10022.9 OEU17097.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) DUF866 PF05907.13 OEU17098.1 - 2.5e-26 92.5 0.1 2.9e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Pyr_redox_2 PF07992.14 OEU17099.1 - 1.5e-25 90.0 0.1 4.3e-15 55.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OEU17099.1 - 6.3e-22 77.5 0.1 1.1e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OEU17099.1 - 5.8e-09 36.1 0.0 1.7e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OEU17099.1 - 1.1e-08 35.6 3.9 3.5e-07 30.7 0.5 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OEU17099.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OEU17099.1 - 5.4e-06 25.9 0.1 0.014 14.7 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU17099.1 - 1.6e-05 24.5 0.0 1.6e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OEU17099.1 - 3.9e-05 22.6 0.3 3.9e-05 22.6 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OEU17099.1 - 5e-05 22.6 0.2 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OEU17099.1 - 6.3e-05 22.7 1.5 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU17099.1 - 0.00032 20.1 0.2 0.00032 20.1 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OEU17099.1 - 0.00036 19.7 0.0 0.00036 19.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OEU17099.1 - 0.00047 19.6 0.3 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OEU17099.1 - 0.0021 18.5 0.1 0.24 11.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding zf-CRD PF17979.1 OEU17099.1 - 0.0052 16.9 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions GIDA PF01134.22 OEU17099.1 - 0.0062 15.7 1.6 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OEU17099.1 - 0.0071 16.3 0.1 0.11 12.5 0.1 2.6 2 1 1 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OEU17099.1 - 0.02 14.2 1.3 0.059 12.7 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 OEU17099.1 - 0.052 12.0 0.0 0.25 9.7 0.0 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 OEU17099.1 - 0.069 12.2 0.1 0.069 12.2 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 OEU17099.1 - 0.09 11.9 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 OEU17099.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YjeF_N PF03853.15 OEU17099.1 - 0.15 12.0 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.23 OEU17099.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 OEU17099.1 - 0.18 11.7 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OEU17099.1 - 0.82 10.0 0.0 0.82 10.0 0.0 2.4 3 0 0 3 3 2 0 TrkA-N domain Ribosomal_S8e PF01201.22 OEU17100.1 - 7.5e-44 149.2 9.7 6.1e-43 146.3 9.7 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Mito_carr PF00153.27 OEU17101.1 - 5.1e-07 29.5 4.0 0.0017 18.2 0.2 4.2 2 2 2 4 4 4 2 Mitochondrial carrier protein PsbX PF06596.11 OEU17101.1 - 6.1 6.9 5.1 9.1 6.4 0.1 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) SPC25 PF06703.11 OEU17102.1 - 4.7e-30 104.5 0.1 9.1e-30 103.6 0.1 1.4 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) UAA PF08449.11 OEU17103.1 - 9.8e-49 166.2 24.3 1.1e-48 166.0 24.3 1.0 1 0 0 1 1 1 1 UAA transporter family DUF2157 PF09925.9 OEU17103.1 - 2.2 8.1 10.3 1.3 8.8 5.4 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Arf PF00025.21 OEU17105.1 - 3.7e-44 150.2 0.0 4.5e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OEU17105.1 - 7.7e-13 48.3 0.0 9.1e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU17105.1 - 2e-10 41.0 0.0 5.8e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OEU17105.1 - 2.8e-08 33.4 0.0 3.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OEU17105.1 - 3.9e-08 32.9 0.2 2.5e-06 26.9 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 OEU17105.1 - 9.1e-08 31.7 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU17105.1 - 3e-07 30.5 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU17105.1 - 0.00044 19.8 0.1 0.047 13.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU17105.1 - 0.012 15.5 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OEU17105.1 - 0.068 13.4 0.1 0.33 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OEU17105.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 OEU17105.1 - 0.2 11.3 0.3 8.6 5.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Inhibitor_I29 PF08246.12 OEU17107.1 - 0.0037 17.7 0.3 0.0037 17.7 0.3 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) HEAT_EZ PF13513.6 OEU17108.1 - 1e-14 54.6 0.1 2.5e-07 31.0 0.0 6.8 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.22 OEU17108.1 - 5.7e-09 35.5 9.6 0.00012 22.1 0.1 8.9 10 0 0 10 10 9 1 HEAT repeat HEAT_2 PF13646.6 OEU17108.1 - 1.1e-06 28.9 2.6 0.021 15.2 0.0 5.8 3 2 3 6 6 6 2 HEAT repeats MMS19_C PF12460.8 OEU17108.1 - 2.9e-05 23.4 3.7 0.1 11.7 3.1 3.6 2 1 2 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OEU17108.1 - 4.3e-05 23.2 1.3 0.96 9.0 0.0 4.6 3 1 2 5 5 5 2 CLASP N terminal Adaptin_N PF01602.20 OEU17108.1 - 4.6e-05 22.2 6.6 0.014 14.0 2.2 3.6 3 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OEU17108.1 - 0.00019 22.0 1.3 0.6 10.8 0.2 5.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OEU17108.1 - 0.00043 20.4 5.9 0.00089 19.3 0.2 3.7 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 OEU17108.1 - 0.00065 18.1 5.2 0.0051 15.2 2.7 3.1 2 1 2 4 4 4 1 Down-regulated in metastasis Tti2 PF10521.9 OEU17108.1 - 0.009 15.6 0.2 1.8 8.0 0.0 3.3 2 1 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 OEU17108.1 - 0.018 15.2 1.7 2.1 8.6 0.0 4.4 2 1 3 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 OEU17108.1 - 0.07 12.2 0.0 0.67 9.0 0.0 2.6 2 0 0 2 2 2 0 Dopey, N-terminal Arm PF00514.23 OEU17108.1 - 0.085 12.9 9.5 12 6.1 0.0 6.1 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 OEU17108.1 - 0.1 12.6 4.7 9.6 6.1 0.1 4.3 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central Cnd3 PF12719.7 OEU17108.1 - 0.31 10.2 11.2 0.017 14.3 1.5 3.2 3 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain PUL PF08324.11 OEU17108.1 - 1.7 7.8 7.8 0.31 10.3 0.7 2.8 2 1 1 3 3 3 0 PUL domain FlxA PF14282.6 OEU17110.1 - 0.45 10.5 4.3 1.2 9.2 0.9 2.9 2 0 0 2 2 2 0 FlxA-like protein Arm-DNA-bind_5 PF17293.2 OEU17110.1 - 0.54 10.7 4.4 1.2 9.7 0.3 2.9 2 0 0 2 2 2 0 Arm DNA-binding domain Pkinase PF00069.25 OEU17111.1 - 2.8e-61 207.2 0.0 4.1e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17111.1 - 5.9e-31 107.7 0.0 8.9e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OEU17111.1 - 1.1e-05 25.8 0.5 0.00056 20.3 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair Kinase-like PF14531.6 OEU17111.1 - 7.2e-05 22.2 0.0 0.00025 20.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OEU17111.1 - 0.00015 21.2 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_6 PF13405.6 OEU17111.1 - 0.00022 20.9 0.6 0.13 12.2 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain APH PF01636.23 OEU17111.1 - 0.001 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU17111.1 - 0.0023 16.8 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_1 PF00036.32 OEU17111.1 - 0.0097 15.4 3.7 0.089 12.4 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 OEU17111.1 - 0.087 12.4 0.2 0.64 9.6 0.0 2.4 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 OEU17112.1 - 2.3e-62 210.8 0.0 3.8e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17112.1 - 3.2e-31 108.6 0.0 5.9e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OEU17112.1 - 9.3e-10 38.8 0.8 0.00034 21.0 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU17112.1 - 1.2e-07 30.8 3.4 0.0046 16.4 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OEU17112.1 - 2e-07 30.4 5.2 0.01 15.7 0.1 3.9 5 0 0 5 5 5 2 EF-hand domain Kinase-like PF14531.6 OEU17112.1 - 0.00013 21.4 0.0 0.00034 20.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like EF-hand_8 PF13833.6 OEU17112.1 - 0.00042 20.1 0.4 0.32 10.9 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain pair Kdo PF06293.14 OEU17112.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU17112.1 - 0.0043 17.0 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_5 PF13202.6 OEU17112.1 - 0.052 13.1 0.9 6.3 6.5 0.1 2.6 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 OEU17112.1 - 0.066 13.5 0.0 6.6 7.1 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain FTA2 PF13095.6 OEU17112.1 - 0.078 12.6 0.1 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2730 PF10805.8 OEU17113.1 - 0.0016 18.5 1.4 0.0016 18.5 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) SlyX PF04102.12 OEU17113.1 - 0.0071 16.9 0.4 0.0071 16.9 0.4 2.5 2 2 1 3 3 2 1 SlyX JAKMIP_CC3 PF16034.5 OEU17113.1 - 0.03 14.3 1.4 0.03 14.3 1.4 2.3 1 1 0 2 2 2 0 JAKMIP CC3 domain KxDL PF10241.9 OEU17113.1 - 0.057 13.7 7.4 0.32 11.3 1.9 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein DicB PF05358.11 OEU17113.1 - 0.06 13.5 0.3 0.83 9.8 0.1 2.3 2 0 0 2 2 2 0 DicB protein CENP-F_leu_zip PF10473.9 OEU17113.1 - 0.071 13.1 9.8 0.032 14.2 3.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 OEU17113.1 - 0.086 11.9 3.4 0.12 11.5 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4349 PF14257.6 OEU17113.1 - 0.091 12.2 4.0 0.15 11.5 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3450 PF11932.8 OEU17113.1 - 0.1 11.9 5.5 0.16 11.2 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 OEU17113.1 - 0.31 9.7 7.8 0.38 9.4 7.8 1.1 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 OEU17113.1 - 0.49 10.9 6.5 0.13 12.7 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 BRE1 PF08647.11 OEU17113.1 - 0.53 10.4 7.6 0.15 12.1 2.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 OEU17113.1 - 1.5 8.6 7.6 4.2 7.2 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) zf-C4H2 PF10146.9 OEU17113.1 - 3.3 7.9 9.3 1.5 9.1 4.0 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DivIC PF04977.15 OEU17113.1 - 5.1 6.9 9.6 0.85 9.4 2.0 2.5 1 1 0 2 2 2 0 Septum formation initiator Fib_alpha PF08702.10 OEU17113.1 - 6.9 6.9 10.6 1.4 9.1 5.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 OEU17114.1 - 0.0016 17.8 8.0 0.0016 17.8 8.0 2.9 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 OEU17114.1 - 0.0024 18.1 8.6 0.0024 18.1 8.6 2.7 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 HALZ PF02183.18 OEU17114.1 - 0.85 9.9 9.5 0.22 11.8 0.4 3.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 OEU17114.1 - 1.7 8.2 20.2 2.2 7.9 11.5 3.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Pox_F11 PF04943.12 OEU17114.1 - 1.9 7.5 15.7 0.026 13.6 6.3 2.0 1 1 1 2 2 2 0 Poxvirus F11 protein Spc7 PF08317.11 OEU17114.1 - 2.4 7.0 25.5 0.21 10.4 6.8 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OEU17114.1 - 3.2 7.8 29.6 8.2 6.5 12.0 3.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinesin PF00225.23 OEU17115.1 - 2.6e-94 315.9 0.0 2.9e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU17115.1 - 7.5e-47 159.0 0.0 1.2e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 OEU17115.1 - 0.0042 17.7 2.8 3.1 8.5 0.8 2.9 2 0 0 2 2 2 2 Initiation control protein YabA PIG-S PF10510.9 OEU17116.1 - 0.42 9.4 2.4 0.47 9.2 2.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein CDC45 PF02724.14 OEU17116.1 - 8.2 4.6 12.0 10 4.2 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Snurportin1 PF11538.8 OEU17116.1 - 9 6.6 11.7 0.61 10.3 4.7 2.3 2 0 0 2 2 2 0 Snurportin1 ETC_C1_NDUFA4 PF04800.12 OEU17117.1 - 2.3e-15 56.6 0.1 4e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region WGR PF05406.15 OEU17118.1 - 0.0088 16.1 2.0 0.017 15.2 0.5 2.1 2 0 0 2 2 2 1 WGR domain Cytochrome_P460 PF16694.5 OEU17118.1 - 0.095 13.1 2.0 2.1 8.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome P460 MMTV_SAg PF01054.17 OEU17119.1 - 0.086 12.4 0.0 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen HEAT_EZ PF13513.6 OEU17120.1 - 1.1e-14 54.6 0.1 2.5e-07 31.0 0.0 6.8 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.22 OEU17120.1 - 4.9e-09 35.7 9.6 0.00012 22.1 0.1 8.9 10 0 0 10 10 9 1 HEAT repeat HEAT_2 PF13646.6 OEU17120.1 - 1.3e-06 28.7 2.9 0.021 15.2 0.0 5.9 3 2 3 6 6 6 2 HEAT repeats MMS19_C PF12460.8 OEU17120.1 - 2.9e-05 23.4 3.7 0.1 11.7 3.1 3.6 2 1 2 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OEU17120.1 - 4.3e-05 23.2 1.3 0.96 9.0 0.0 4.6 3 1 2 5 5 5 2 CLASP N terminal Adaptin_N PF01602.20 OEU17120.1 - 5.4e-05 22.0 6.8 0.014 14.0 2.2 3.6 3 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OEU17120.1 - 0.00019 22.0 1.3 0.6 10.8 0.2 5.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OEU17120.1 - 0.00043 20.4 5.9 0.00089 19.3 0.2 3.7 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 OEU17120.1 - 0.00064 18.2 5.2 0.0051 15.2 2.7 3.1 2 1 2 4 4 4 1 Down-regulated in metastasis Tti2 PF10521.9 OEU17120.1 - 0.0087 15.6 0.2 1.8 8.0 0.0 3.3 2 1 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 OEU17120.1 - 0.018 15.2 1.7 2.1 8.6 0.0 4.4 2 1 3 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 OEU17120.1 - 0.021 14.9 8.4 12 6.1 0.0 6.4 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 OEU17120.1 - 0.07 12.2 0.0 0.67 9.0 0.0 2.6 2 0 0 2 2 2 0 Dopey, N-terminal Cnd3 PF12719.7 OEU17120.1 - 0.29 10.3 11.1 0.017 14.3 1.5 3.2 3 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain UNC45-central PF11701.8 OEU17120.1 - 0.43 10.5 6.6 9.6 6.1 0.1 4.3 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central PUL PF08324.11 OEU17120.1 - 1.7 7.8 7.8 0.31 10.3 0.7 2.8 2 1 1 3 3 3 0 PUL domain Inhibitor_I29 PF08246.12 OEU17121.1 - 0.0037 17.7 0.3 0.0037 17.7 0.3 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Arf PF00025.21 OEU17123.1 - 2.8e-44 150.6 0.0 3.4e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OEU17123.1 - 6e-13 48.7 0.0 7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU17123.1 - 1.9e-10 41.0 0.0 5.6e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OEU17123.1 - 2.7e-08 33.5 0.0 3.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OEU17123.1 - 5.4e-08 32.4 0.2 3.3e-06 26.5 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 OEU17123.1 - 8.7e-08 31.8 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU17123.1 - 3.1e-07 30.5 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU17123.1 - 0.0005 19.7 0.1 0.054 13.0 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU17123.1 - 0.01 15.7 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OEU17123.1 - 0.07 13.4 0.1 0.36 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OEU17123.1 - 0.18 11.3 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B UAA PF08449.11 OEU17125.1 - 1.8e-48 165.3 24.6 2e-48 165.1 24.6 1.0 1 0 0 1 1 1 1 UAA transporter family Gram_pos_anchor PF00746.21 OEU17125.1 - 0.36 10.8 1.4 0.65 10.0 0.2 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF2157 PF09925.9 OEU17125.1 - 4.2 7.2 10.9 1.3 8.9 5.1 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SPC25 PF06703.11 OEU17126.1 - 4.7e-30 104.5 0.1 9.1e-30 103.6 0.1 1.4 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Mito_carr PF00153.27 OEU17127.1 - 7.9e-08 32.1 4.4 0.0018 18.2 0.2 4.2 2 2 1 3 3 3 3 Mitochondrial carrier protein PsbX PF06596.11 OEU17127.1 - 6.5 6.8 5.1 9.5 6.3 0.1 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Ribosomal_S8e PF01201.22 OEU17128.1 - 7.5e-44 149.2 9.7 6.1e-43 146.3 9.7 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Pyr_redox_2 PF07992.14 OEU17129.1 - 3.6e-28 98.7 0.1 1.4e-27 96.8 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OEU17129.1 - 7.3e-22 77.3 0.1 1.2e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 OEU17129.1 - 4.4e-11 43.2 0.1 3.7e-07 30.6 0.5 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU17129.1 - 6.5e-09 35.9 0.0 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU17129.1 - 1.5e-06 27.8 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OEU17129.1 - 1.5e-06 27.7 0.1 0.017 14.4 0.0 3.3 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU17129.1 - 1.8e-06 26.9 0.2 4e-05 22.5 0.3 2.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OEU17129.1 - 1.7e-05 24.4 0.1 1.7e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OEU17129.1 - 3.8e-05 23.0 0.1 0.0013 18.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OEU17129.1 - 0.00019 21.1 0.0 0.00019 21.1 0.0 2.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU17129.1 - 0.00033 20.0 0.2 0.00033 20.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OEU17129.1 - 0.00038 19.7 0.0 0.00038 19.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OEU17129.1 - 0.00045 19.6 0.1 0.0054 16.1 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OEU17129.1 - 0.0011 18.3 0.1 0.063 12.6 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OEU17129.1 - 0.0012 18.8 0.2 0.11 12.5 0.1 2.8 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OEU17129.1 - 0.0014 19.0 0.1 0.24 11.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 OEU17129.1 - 0.0017 17.5 0.3 0.024 13.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A zf-CRD PF17979.1 OEU17129.1 - 0.0056 16.8 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions Lycopene_cycl PF05834.12 OEU17129.1 - 0.019 14.0 0.1 0.072 12.1 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 OEU17129.1 - 0.02 13.3 0.0 0.26 9.6 0.0 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OEU17129.1 - 0.041 13.0 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 OEU17129.1 - 0.062 13.6 0.2 0.85 9.9 0.0 2.6 3 0 0 3 3 2 0 TrkA-N domain AdoHcyase_NAD PF00670.21 OEU17129.1 - 0.065 13.3 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain YjeF_N PF03853.15 OEU17129.1 - 0.087 12.7 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.23 OEU17129.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 OEU17129.1 - 0.15 12.1 0.0 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OEU17129.1 - 0.15 11.6 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF866 PF05907.13 OEU17130.1 - 6.8e-27 94.3 0.2 8e-27 94.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PDEase_I PF00233.19 OEU17131.1 - 1.6e-70 237.5 0.0 1.9e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase adh_short PF00106.25 OEU17132.1 - 5.4e-20 71.7 0.7 5.7e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17132.1 - 1.6e-06 27.8 0.2 0.0036 16.9 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OEU17132.1 - 0.018 14.5 1.1 0.031 13.7 0.1 1.9 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family DUF3245 PF11595.8 OEU17132.1 - 0.074 13.5 1.8 0.085 13.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) TFIIE-A_C PF11521.8 OEU17132.1 - 1.5 9.2 6.8 1.6 9.0 2.7 2.7 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha HA2 PF04408.23 OEU17133.1 - 3.6e-18 65.8 1.5 2.5e-17 63.1 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OEU17133.1 - 1.1e-15 57.7 0.2 4.3e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OEU17133.1 - 1.1e-10 41.9 0.9 3e-09 37.2 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU17133.1 - 6.3e-05 22.8 0.4 0.00044 20.1 0.2 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OEU17133.1 - 0.12 12.7 1.4 0.7 10.2 0.1 2.9 3 1 0 3 3 3 0 AAA domain NST1 PF13945.6 OEU17133.1 - 8.7 6.4 15.4 5.2 7.1 10.5 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator HECT PF00632.25 OEU17134.1 - 1e-30 107.3 0.0 2.3e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OEU17134.1 - 1.5e-05 25.1 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Pkinase PF00069.25 OEU17135.1 - 8.5e-53 179.4 0.0 9.9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17135.1 - 1.3e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU17135.1 - 0.00026 20.4 0.2 0.0004 19.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OEU17135.1 - 0.0022 17.6 0.7 0.012 15.2 0.1 2.0 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 OEU17135.1 - 0.0055 16.1 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like GP44 PF17510.2 OEU17135.1 - 0.037 14.3 0.1 0.077 13.3 0.1 1.5 1 0 0 1 1 1 0 Gene product 44 APH PF01636.23 OEU17135.1 - 0.06 13.3 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Gemini_AL2 PF01440.16 OEU17136.1 - 0.76 10.2 4.2 1.2 9.6 0.8 2.4 1 1 1 2 2 2 0 Geminivirus AL2 protein Folate_carrier PF01770.18 OEU17137.1 - 0.0014 17.5 3.8 0.014 14.1 3.5 2.0 2 0 0 2 2 2 1 Reduced folate carrier DUF4834 PF16118.5 OEU17137.1 - 0.66 11.0 17.0 0.76 10.8 6.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Connexin PF00029.19 OEU17137.1 - 0.89 9.3 4.0 2.7 7.7 3.2 2.1 2 0 0 2 2 2 0 Connexin Mucin PF01456.17 OEU17137.1 - 1.3 9.0 21.2 2.3 8.2 4.4 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein HSA PF07529.13 OEU17138.1 - 5.1e-09 36.3 0.1 1.8e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 HSA Myb_DNA-bind_6 PF13921.6 OEU17138.1 - 0.00085 19.5 0.1 0.0031 17.7 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OEU17138.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain ResIII PF04851.15 OEU17138.1 - 0.05 13.6 0.0 0.35 10.9 0.0 2.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FAD_binding_3 PF01494.19 OEU17139.1 - 7.8e-12 45.1 0.0 7.4e-08 32.0 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 OEU17139.1 - 0.073 12.1 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase mRNA_cap_enzyme PF01331.19 OEU17139.1 - 0.087 12.6 0.1 4.3 7.1 0.0 2.7 3 0 0 3 3 3 0 mRNA capping enzyme, catalytic domain DNA_pol_phi PF04931.13 OEU17140.1 - 3.3 5.7 7.7 6.3 4.8 7.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi XPA_C PF05181.12 OEU17142.1 - 8.3e-08 32.1 0.1 1.6e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus CiPC PF15800.5 OEU17142.1 - 0.019 14.7 7.4 0.021 14.6 7.4 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian VGCC_beta4Aa_N PF12052.8 OEU17142.1 - 0.47 10.6 5.7 1.5 9.0 5.7 1.9 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF4551 PF15087.6 OEU17142.1 - 0.58 8.9 14.1 0.7 8.7 14.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 OEU17142.1 - 0.66 8.7 8.7 0.56 8.9 8.7 1.2 1 0 0 1 1 1 0 Presenilin Dapper PF15268.6 OEU17142.1 - 1.9 7.3 14.8 2.3 7.0 14.8 1.1 1 0 0 1 1 1 0 Dapper Membralin PF09746.9 OEU17142.1 - 6.1 5.8 6.3 6.4 5.7 6.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Cellulose_synt PF03552.14 OEU17142.1 - 6.4 5.1 5.6 8.6 4.7 5.6 1.2 1 0 0 1 1 1 0 Cellulose synthase ALMT PF11744.8 OEU17142.1 - 7 5.4 9.1 9.1 5.0 9.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 OEU17142.1 - 8.7 5.5 6.7 9.1 5.4 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HSF_DNA-bind PF00447.17 OEU17144.1 - 1.7e-19 70.2 0.7 2.2e-19 69.9 0.7 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding MFS_1 PF07690.16 OEU17145.1 - 4.1e-18 65.4 23.3 1.1e-10 41.0 5.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 OEU17145.1 - 1.9 8.0 6.2 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) zf-RING_2 PF13639.6 OEU17146.1 - 3.5e-13 49.6 4.1 7.9e-13 48.5 4.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU17146.1 - 1.4e-10 40.9 4.8 3e-10 39.8 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU17146.1 - 8.3e-10 38.8 5.2 3e-09 37.0 5.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OEU17146.1 - 6.2e-08 32.6 2.3 1.2e-07 31.7 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OEU17146.1 - 1.5e-07 31.2 3.5 3.5e-07 30.0 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU17146.1 - 2.9e-06 26.9 1.3 2.9e-06 26.9 1.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OEU17146.1 - 2.3e-05 24.2 2.1 6.5e-05 22.7 2.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU17146.1 - 2.6e-05 24.1 3.8 7.7e-05 22.6 3.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU17146.1 - 2.9e-05 24.0 0.5 0.00018 21.5 0.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 OEU17146.1 - 0.012 15.7 7.0 0.032 14.4 7.0 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 OEU17146.1 - 0.013 15.3 4.1 0.044 13.6 4.1 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OEU17146.1 - 0.013 15.6 5.8 0.054 13.7 5.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 OEU17146.1 - 0.014 15.2 1.5 0.031 14.1 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OEU17146.1 - 0.031 14.1 3.2 0.1 12.5 3.2 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU17146.1 - 0.058 13.0 6.8 0.14 11.8 6.8 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4834 PF16118.5 OEU17146.1 - 0.095 13.7 0.2 0.095 13.7 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) zf-RING-like PF08746.11 OEU17146.1 - 0.18 12.1 5.5 0.51 10.7 5.5 1.8 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.6 OEU17146.1 - 0.3 11.3 3.7 0.3 11.3 1.2 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain OSTbeta PF15048.6 OEU17146.1 - 0.35 11.0 3.5 3.6 7.8 0.0 2.7 2 1 0 2 2 2 0 Organic solute transporter subunit beta protein PHD PF00628.29 OEU17146.1 - 0.52 10.2 8.6 0.55 10.2 5.7 2.5 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 OEU17146.1 - 2.6 8.0 9.3 2.5 8.1 2.9 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 PAP_fibrillin PF04755.12 OEU17149.1 - 3.9e-12 46.5 3.0 9.1e-10 38.8 3.0 2.9 1 1 0 1 1 1 1 PAP_fibrillin Gp49 PF05973.14 OEU17149.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) LSM14 PF12701.7 OEU17152.1 - 1.1e-26 92.7 0.0 1.9e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OEU17152.1 - 2.3e-05 25.2 9.8 2.3e-05 25.2 9.8 3.5 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.6 OEU17152.1 - 0.00045 20.3 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain SOG2 PF10428.9 OEU17152.1 - 0.16 11.2 16.3 0.016 14.5 11.9 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein YqzL PF14006.6 OEU17152.1 - 0.33 11.4 1.8 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 YqzL-like protein Hid1 PF12722.7 OEU17152.1 - 4.9 5.2 6.6 7.2 4.6 6.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein bZIP_2 PF07716.15 OEU17155.1 - 1.3 9.1 7.0 0.66 10.1 1.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SID-1_RNA_chan PF13965.6 OEU17156.1 - 0.13 10.7 0.7 0.34 9.3 0.7 1.7 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CRAL_TRIO PF00650.20 OEU17158.1 - 2.7e-14 53.2 0.0 5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain JAB PF01398.21 OEU17159.1 - 4.5e-32 110.5 0.0 9.7e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OEU17159.1 - 1.4e-14 54.5 0.7 2.3e-14 53.8 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OEU17159.1 - 3.5e-06 26.8 0.0 5.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 OEU17159.1 - 0.0056 16.8 0.2 0.0099 16.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) KaiA PF07688.12 OEU17159.1 - 0.18 12.0 2.0 0.28 11.3 0.7 2.0 2 1 0 2 2 2 0 KaiA C-terminal domain Smoothelin PF12510.8 OEU17159.1 - 0.2 11.8 0.5 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Mito_carr PF00153.27 OEU17160.1 - 1.1e-25 89.3 3.4 6.4e-11 42.0 0.2 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 OEU17161.1 - 3.6e-62 209.4 0.2 7e-62 208.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OEU17161.1 - 5.7e-29 100.4 0.0 2.2e-28 98.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OEU17161.1 - 1.4e-22 79.6 0.0 4.4e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OEU17161.1 - 4e-14 52.8 0.1 2.7e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OEU17161.1 - 8.5e-13 48.2 0.0 2.3e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OEU17161.1 - 0.012 15.6 0.0 0.041 14.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Tti2 PF10521.9 OEU17162.1 - 0.006 16.2 0.4 0.64 9.5 0.1 2.9 2 0 0 2 2 2 2 Tti2 family DUF3730 PF12530.8 OEU17162.1 - 0.02 14.4 0.6 0.02 14.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) RIX1 PF08167.12 OEU17162.1 - 0.032 14.0 2.1 0.62 9.8 1.0 3.5 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT PF02985.22 OEU17162.1 - 0.1 12.9 0.5 5.2 7.6 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat ThiF PF00899.21 OEU17163.1 - 4.8e-57 193.1 0.0 6.5e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OEU17163.1 - 0.00095 19.7 0.1 0.009 16.5 0.0 2.8 2 1 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 OEU17163.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OEU17163.1 - 0.077 12.6 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RuvX PF03652.15 OEU17163.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction resolvase CTNNBL PF08216.11 OEU17164.1 - 3.5e-21 75.3 0.5 9e-21 74.0 0.5 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.6 OEU17164.1 - 0.0016 18.8 0.1 0.0073 16.7 0.0 2.1 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 OEU17164.1 - 0.055 13.5 0.1 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OEU17164.1 - 0.093 13.0 0.1 0.9 10.0 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat PHD PF00628.29 OEU17165.1 - 2e-10 40.4 8.9 2.3e-10 40.2 7.1 2.0 2 0 0 2 2 2 1 PHD-finger PLU-1 PF08429.11 OEU17165.1 - 1.6e-05 24.3 2.3 1.6e-05 24.3 2.3 2.3 2 0 0 2 2 2 1 PLU-1-like protein BUD22 PF09073.10 OEU17165.1 - 0.012 15.0 6.9 0.012 15.0 6.9 2.1 2 1 0 2 2 2 0 BUD22 PHD_2 PF13831.6 OEU17165.1 - 0.021 14.4 2.4 0.021 14.4 2.4 2.0 2 0 0 2 2 2 0 PHD-finger Suf PF05843.14 OEU17165.1 - 0.027 14.5 2.5 0.048 13.7 2.5 1.5 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) zf-PHD-like PF15446.6 OEU17165.1 - 0.045 13.4 6.6 0.11 12.2 6.6 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Wbp11 PF09429.10 OEU17165.1 - 0.43 11.0 15.7 0.094 13.1 8.2 2.6 2 0 0 2 2 2 0 WW domain binding protein 11 DnaJ PF00226.31 OEU17166.1 - 4.2e-21 74.8 2.1 1.5e-20 73.0 2.1 2.0 1 0 0 1 1 1 1 DnaJ domain HAT_KAT11 PF08214.11 OEU17169.1 - 1.3e-32 113.4 0.0 2.9e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Histone acetylation protein zf-TAZ PF02135.16 OEU17169.1 - 9.9e-26 90.0 56.7 1.7e-15 57.2 19.4 3.9 3 0 0 3 3 3 2 TAZ zinc finger Bromodomain PF00439.25 OEU17169.1 - 1.7e-20 72.9 0.1 1.2e-19 70.1 0.0 2.5 3 0 0 3 3 3 1 Bromodomain ZZ PF00569.17 OEU17169.1 - 2.4e-07 30.4 7.6 2.4e-07 30.4 7.6 3.1 3 0 0 3 3 3 1 Zinc finger, ZZ type KIX_2 PF16987.5 OEU17169.1 - 7.1e-06 25.9 0.3 7.1e-06 25.9 0.3 2.3 2 0 0 2 2 2 1 KIX domain PHD PF00628.29 OEU17169.1 - 1.1e-05 25.2 8.4 1.1e-05 25.2 8.4 4.0 3 0 0 3 3 3 1 PHD-finger AAA_12 PF13087.6 OEU17171.1 - 1.6e-18 67.1 0.0 1.4e-17 64.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain MTES_1575 PF18741.1 OEU17171.1 - 3.6e-08 33.5 1.8 3e-05 24.1 0.4 2.7 2 0 0 2 2 2 2 REase_MTES_1575 AAA_11 PF13086.6 OEU17171.1 - 1.5e-07 31.5 2.8 0.0002 21.3 0.3 3.6 4 1 0 4 4 4 2 AAA domain AAA_19 PF13245.6 OEU17171.1 - 1.5e-05 25.3 0.6 0.0012 19.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OEU17171.1 - 4.4e-05 23.3 0.0 0.0045 16.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 OEU17171.1 - 0.00094 19.1 0.0 0.031 14.1 0.1 2.5 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 OEU17171.1 - 0.015 14.9 1.1 0.1 12.1 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NPV_P10 PF05531.12 OEU17171.1 - 0.091 13.2 1.5 0.4 11.2 0.4 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 OEU17171.1 - 1.5 8.3 4.6 0.74 9.3 1.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 OEU17171.1 - 4 7.5 6.0 1.1 9.4 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SOR_SNZ PF01680.17 OEU17172.1 - 9.2e-110 365.3 7.2 1.2e-109 364.9 7.2 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OEU17172.1 - 1.1e-07 31.5 6.4 2.3e-06 27.1 0.4 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OEU17172.1 - 4.2e-05 22.8 0.2 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 OEU17172.1 - 0.00025 21.1 0.0 0.00069 19.6 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 OEU17172.1 - 0.00079 18.9 0.7 0.032 13.7 0.1 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 OEU17172.1 - 0.0018 17.5 1.0 0.016 14.4 0.1 2.3 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 OEU17172.1 - 0.0034 16.8 5.4 0.0036 16.7 0.5 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase OMPdecase PF00215.24 OEU17172.1 - 0.004 16.8 0.4 1.8 8.1 0.2 2.3 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family IMPDH PF00478.25 OEU17172.1 - 0.016 14.2 0.2 0.026 13.5 0.2 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 OEU17172.1 - 0.019 14.2 0.2 0.33 10.1 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase tRNA-synt_2 PF00152.20 OEU17173.1 - 1.5e-84 283.7 0.0 2.3e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OEU17173.1 - 1.3e-09 37.9 1.1 2.4e-09 37.0 1.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OEU17173.1 - 0.0021 17.6 0.6 2.2 7.7 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) 3Beta_HSD PF01073.19 OEU17174.1 - 5.8e-34 117.4 0.0 7.1e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OEU17174.1 - 8.6e-27 94.1 0.0 1.1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU17174.1 - 3.8e-14 52.8 0.0 3.3e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OEU17174.1 - 2.2e-12 46.7 0.0 3.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OEU17174.1 - 5.7e-09 35.5 0.0 3.1e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OEU17174.1 - 5.4e-08 32.3 0.0 7.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OEU17174.1 - 4.9e-05 23.3 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OEU17174.1 - 0.0029 17.1 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17174.1 - 0.0063 16.1 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU17174.1 - 0.0089 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF983 PF06170.12 OEU17174.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) NmrA PF05368.13 OEU17174.1 - 0.11 12.0 0.7 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Viral_Beta_CD PF04530.12 OEU17175.1 - 0.18 12.1 0.3 0.26 11.6 0.3 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family Glycos_transf_2 PF00535.26 OEU17176.1 - 1.3e-12 47.9 0.0 9.8e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Tmemb_40 PF10160.9 OEU17176.1 - 0.049 13.1 0.5 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein ApoC-I PF04691.12 OEU17176.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Alanine_zipper PF11839.8 OEU17177.1 - 0.017 15.5 0.5 0.017 15.5 0.5 2.0 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Lectin_N PF03954.14 OEU17177.1 - 0.025 14.3 10.9 0.15 11.8 1.3 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.8 OEU17177.1 - 0.2 9.1 29.3 0.3 8.5 29.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM184 PF15665.5 OEU17177.1 - 5.5 6.7 35.7 3.3 7.4 28.9 2.8 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF948 PF06103.11 OEU17177.1 - 7 7.0 14.8 0.98 9.7 2.2 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GFO_IDH_MocA PF01408.22 OEU17178.1 - 9.7e-19 68.4 0.0 1.6e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 OEU17178.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 OEU17178.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain 2-Hacid_dh_C PF02826.19 OEU17178.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aa_trans PF01490.18 OEU17179.1 - 1.1e-43 149.6 18.0 4.3e-34 117.9 15.2 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CRAL_TRIO PF00650.20 OEU17180.1 - 2e-14 53.6 0.0 3.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU17180.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain FMO-like PF00743.19 OEU17181.1 - 3.9e-46 157.6 0.0 1.4e-39 136.0 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OEU17181.1 - 5.2e-15 55.5 0.0 1.8e-07 30.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OEU17181.1 - 1.5e-09 37.6 0.0 2.9e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU17181.1 - 1.3e-06 28.6 0.0 7.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU17181.1 - 2.4e-06 27.4 0.0 0.0023 17.6 0.0 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU17181.1 - 1.7e-05 24.3 0.3 3.4e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OEU17181.1 - 0.0035 16.1 0.1 0.014 14.2 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OEU17181.1 - 0.0043 16.2 0.1 0.0065 15.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OEU17181.1 - 0.0046 16.2 0.1 0.016 14.4 0.2 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OEU17181.1 - 0.013 16.1 0.1 5 7.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OEU17181.1 - 0.023 14.0 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 OEU17181.1 - 0.11 11.6 1.0 24 3.9 0.0 3.6 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OEU17181.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 OEU17181.1 - 0.18 11.8 0.0 2 8.4 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus BING4CT PF08149.11 OEU17182.1 - 9.5e-33 111.9 0.0 1.1e-31 108.4 0.0 2.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 OEU17182.1 - 1.7e-06 28.7 5.4 4e-06 27.4 0.0 4.1 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU17182.1 - 1.8e-06 28.1 0.0 0.065 13.5 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-HC5HC2H PF13771.6 OEU17184.1 - 0.0023 18.1 5.4 0.014 15.7 5.4 2.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain TPR_MLP1_2 PF07926.12 OEU17184.1 - 0.0032 17.5 24.4 0.0032 17.5 24.4 3.8 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein zf-HC5HC2H_2 PF13832.6 OEU17184.1 - 0.23 11.6 8.0 0.13 12.4 5.2 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain Vpu PF00558.19 OEU17184.1 - 6 6.7 6.6 2.2 8.1 2.8 2.2 2 0 0 2 2 2 0 Vpu protein DUF1279 PF06916.13 OEU17185.1 - 0.00015 22.2 0.0 0.00023 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) TAtT PF16811.5 OEU17185.1 - 0.23 10.7 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 TRAP transporter T-component Pro_isomerase PF00160.21 OEU17186.1 - 2.1e-38 132.1 0.0 2.5e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Prefoldin PF02996.17 OEU17187.1 - 1.9e-22 79.4 0.1 3e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Ion_trans PF00520.31 OEU17188.1 - 1.9e-39 135.4 38.8 3.8e-25 88.5 19.9 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 OEU17188.1 - 1e-07 32.3 1.0 2.2e-07 31.2 1.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU17188.1 - 2.3e-05 24.0 2.5 0.093 12.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain PKD_channel PF08016.12 OEU17188.1 - 5e-05 22.2 8.1 5e-05 22.2 8.1 4.0 3 1 1 4 4 4 3 Polycystin cation channel EF-hand_1 PF00036.32 OEU17188.1 - 0.00013 21.3 6.1 0.08 12.5 1.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OEU17188.1 - 0.00014 21.7 1.6 0.32 10.9 0.8 2.7 1 1 1 2 2 2 2 EF-hand domain pair Flavin_Reduct PF01613.18 OEU17188.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain EF-hand_5 PF13202.6 OEU17188.1 - 1.8 8.2 6.1 7.6 6.2 0.0 3.1 3 0 0 3 3 3 0 EF hand FAD_binding_8 PF08022.12 OEU17189.1 - 1.8e-14 53.7 0.0 5e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 OEU17189.1 - 3.7e-10 40.0 14.1 3.7e-10 40.0 14.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Glyoxalase PF00903.25 OEU17190.1 - 3.1e-17 62.9 0.0 4.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OEU17190.1 - 0.0066 16.7 0.0 3.7 7.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OEU17190.1 - 0.012 16.4 0.0 0.078 13.8 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain DUF2201_N PF13203.6 OEU17192.1 - 2.9 7.4 6.0 6.1 6.4 5.9 1.6 1 1 0 1 1 1 0 Putative metallopeptidase domain MCM6_C PF18263.1 OEU17193.1 - 0.066 13.4 0.5 0.066 13.4 0.5 2.7 1 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Rhabdo_M1 PF03342.13 OEU17193.1 - 0.19 11.0 5.1 0.28 10.5 5.1 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) SNF2_N PF00176.23 OEU17194.1 - 5.7e-57 193.0 1.4 9e-57 192.4 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU17194.1 - 3.3e-13 50.0 0.0 8.5e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 OEU17194.1 - 5.3e-09 36.0 1.8 5.3e-09 36.0 1.8 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OEU17194.1 - 2e-07 30.7 4.8 2.3e-06 27.4 5.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 OEU17194.1 - 5.5e-07 29.7 2.8 1.3e-06 28.5 0.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 OEU17194.1 - 1.1e-06 28.9 8.8 1.1e-06 28.9 8.8 2.9 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU17194.1 - 2.6e-06 27.2 2.2 2.6e-06 27.2 2.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU17194.1 - 6e-06 26.0 7.3 7e-05 22.6 7.3 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU17194.1 - 0.00017 21.7 1.7 0.00017 21.7 1.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OEU17194.1 - 0.00019 21.2 13.0 0.048 13.5 11.6 4.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OEU17194.1 - 0.00023 21.1 6.9 0.00023 21.1 6.9 2.6 2 1 1 3 3 2 1 zinc-RING finger domain DEAD PF00270.29 OEU17194.1 - 0.0013 18.5 0.1 0.0036 17.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_11 PF17123.5 OEU17194.1 - 0.0046 16.7 3.9 0.0046 16.7 3.9 3.4 4 0 0 4 4 4 1 RING-like zinc finger Cupin_8 PF13621.6 OEU17194.1 - 0.072 12.8 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Cupin-like domain zf-RING_6 PF14835.6 OEU17194.1 - 0.39 10.6 3.7 1.7 8.6 0.9 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 OEU17194.1 - 1.5 9.1 5.3 5.7 7.2 5.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Pribosyltran PF00156.27 OEU17195.1 - 1.9e-26 92.5 0.0 2.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OEU17195.1 - 0.0017 17.9 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 OEU17195.1 - 0.0055 16.2 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase RuBisCO_small PF00101.20 OEU17195.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain COG4 PF08318.12 OEU17197.1 - 1.1e-07 31.2 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein SNF2_N PF00176.23 OEU17198.1 - 1.6e-17 63.3 0.4 1.3e-14 53.7 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU17198.1 - 5.5e-12 46.0 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU17198.1 - 0.00067 19.5 0.9 0.094 12.5 0.0 3.0 2 1 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 OEU17198.1 - 0.00076 19.5 0.6 1.2 9.1 0.1 2.7 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OEU17198.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RRM_1 PF00076.22 OEU17199.1 - 5.6e-10 38.9 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CLP_protease PF00574.23 OEU17200.1 - 2.3e-44 151.5 0.0 3.3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Clp protease ubiquitin PF00240.23 OEU17202.1 - 6e-135 439.2 17.8 4.9e-33 112.7 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 OEU17202.1 - 9.1e-64 211.2 20.9 2.2e-15 56.2 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU17202.1 - 2.3e-24 85.7 8.2 0.00027 21.3 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU17202.1 - 3e-17 62.3 2.3 0.02 14.8 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU17202.1 - 1.3e-14 54.2 1.9 0.12 12.5 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OEU17202.1 - 2.3e-14 53.5 3.9 0.09 13.1 0.0 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 OEU17202.1 - 1.5e-12 48.0 0.9 0.49 11.0 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 OEU17202.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 OEU17202.1 - 9.9e-06 25.5 21.2 25 5.0 0.0 7.9 8 0 0 8 8 8 0 Ubiquitin-like domain UDP-g_GGTase PF06427.11 OEU17202.1 - 7.7e-05 22.8 0.9 12 6.1 0.0 3.9 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase TmoB PF06234.12 OEU17202.1 - 0.00015 21.7 0.1 57 3.9 0.0 4.7 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF969 PF06149.12 OEU17202.1 - 0.00026 20.5 0.0 20 4.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) Raf1_HTH PF18579.1 OEU17202.1 - 0.0042 16.7 0.2 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 OEU17202.1 - 0.0049 16.9 0.0 91 3.3 0.0 4.5 4 0 0 4 4 4 0 ORF11CD3 domain Big_7 PF17957.1 OEU17202.1 - 0.0074 17.0 0.1 2e+02 2.8 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig domain DUF3861 PF12977.7 OEU17202.1 - 0.012 15.8 1.2 1.3e+02 2.9 0.0 4.1 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) FlgD_ig PF13860.6 OEU17202.1 - 0.023 14.5 6.8 55 3.7 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain TraK PF06586.11 OEU17202.1 - 0.033 13.9 0.2 1.3e+02 2.1 0.0 3.9 4 0 0 4 4 4 0 TraK protein Myosin_N PF02736.19 OEU17202.1 - 0.1 12.4 7.9 62 3.5 0.1 5.4 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CorA PF01544.18 OEU17202.1 - 0.13 11.5 0.7 1.4e+02 1.6 0.0 3.7 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein ProRS-C_2 PF09181.10 OEU17202.1 - 0.15 12.2 1.7 2.4e+02 2.0 0.0 3.9 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal MCM6_C PF18263.1 OEU17205.1 - 0.021 15.1 1.9 0.059 13.6 0.4 2.1 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain Pkinase PF00069.25 OEU17206.1 - 2.2e-26 92.8 0.0 2.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17206.1 - 4.3e-22 78.7 0.0 4.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5568 PF17724.1 OEU17207.1 - 0.028 14.2 0.7 0.044 13.6 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5568) Macoilin PF09726.9 OEU17207.1 - 0.25 9.9 2.7 0.29 9.7 2.7 1.1 1 0 0 1 1 1 0 Macoilin family TPR_2 PF07719.17 OEU17208.1 - 0.07 13.3 1.3 4.4 7.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MBF1 PF08523.10 OEU17208.1 - 0.22 12.0 2.9 0.33 11.4 0.9 2.4 2 0 0 2 2 2 0 Multiprotein bridging factor 1 DUF4834 PF16118.5 OEU17208.1 - 0.28 12.1 0.2 0.28 12.1 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DDHD PF02862.17 OEU17208.1 - 0.41 10.8 9.8 0.55 10.4 3.6 2.3 2 0 0 2 2 2 0 DDHD domain DUF5427 PF10310.9 OEU17208.1 - 0.68 8.8 22.5 0.28 10.1 7.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Methyltransf_11 PF08241.12 OEU17209.1 - 1.7e-09 38.2 0.0 4.6e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU17209.1 - 3e-07 31.1 0.0 7.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU17209.1 - 3.2e-06 27.8 0.0 9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU17209.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU17209.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU17209.1 - 0.0093 16.0 0.1 0.036 14.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OEU17209.1 - 0.033 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DUF4201 PF13870.6 OEU17210.1 - 2.1e-05 24.3 51.2 0.0019 18.0 3.6 4.3 2 1 2 4 4 4 3 Domain of unknown function (DUF4201) SHE3 PF17078.5 OEU17210.1 - 0.0026 17.5 19.4 0.0026 17.5 19.4 3.2 1 1 2 3 3 3 1 SWI5-dependent HO expression protein 3 GIT_CC PF16559.5 OEU17210.1 - 0.0042 16.9 0.2 0.0042 16.9 0.2 5.8 5 1 1 6 6 6 2 GIT coiled-coil Rho guanine nucleotide exchange factor Prp19 PF08606.11 OEU17210.1 - 0.1 12.6 0.4 0.1 12.6 0.4 3.5 4 0 0 4 4 4 0 Prp19/Pso4-like FAST_2 PF08368.12 OEU17210.1 - 0.17 12.7 3.0 8.1 7.3 0.2 2.9 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 DASH_Dam1 PF08653.10 OEU17210.1 - 1.5 8.6 10.2 0.27 11.1 0.2 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 Mating_N PF12731.7 OEU17210.1 - 8.3 6.6 7.7 3.3 7.9 0.1 3.4 3 1 0 3 3 3 0 Mating-type protein beta 1 Bestrophin PF01062.21 OEU17212.1 - 2.7e-12 46.7 1.9 8.4e-06 25.4 0.2 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 OEU17212.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.7 1 1 0 1 1 1 1 Phosphate transporter family Chloroa_b-bind PF00504.21 OEU17213.1 - 1.9e-33 116.3 0.1 2.5e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 OEU17214.1 - 1.3e-33 116.8 0.4 1.6e-33 116.5 0.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Thiolase_N PF00108.23 OEU17215.1 - 2.7e-70 236.7 0.5 3.7e-70 236.2 0.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OEU17215.1 - 3.5e-47 159.1 0.4 1.6e-46 156.9 0.2 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 OEU17215.1 - 0.012 15.8 0.3 0.53 10.5 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 OEU17215.1 - 0.075 12.6 0.3 0.24 10.9 0.3 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Bestrophin PF01062.21 OEU17217.1 - 3.3e-11 43.1 6.7 4.8e-11 42.6 6.7 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Transket_pyr PF02779.24 OEU17218.1 - 1.8e-43 148.3 0.1 2.9e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OEU17218.1 - 2.8e-38 130.6 0.1 5.1e-38 129.7 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 OEU17218.1 - 0.1 12.9 0.0 0.58 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II INCENP_ARK-bind PF03941.15 OEU17219.1 - 4.4e-18 65.0 2.0 5.2e-18 64.7 0.4 1.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region FAD-oxidase_C PF02913.19 OEU17220.1 - 2e-44 152.1 0.0 2.6e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OEU17220.1 - 2.6e-33 114.7 3.8 2.9e-33 114.5 1.9 1.9 2 0 0 2 2 2 1 FAD binding domain tRNA-synt_1b PF00579.25 OEU17221.1 - 2.9e-77 259.9 0.0 4.3e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 OEU17221.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 OEU17221.1 - 0.13 12.1 0.1 0.63 9.9 0.1 2.1 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain PDZ_2 PF13180.6 OEU17222.1 - 0.024 15.0 0.3 0.058 13.7 0.3 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 OEU17222.1 - 0.098 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Mito_carr PF00153.27 OEU17223.1 - 5.2e-50 167.3 1.7 2e-19 69.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAT_KAT11 PF08214.11 OEU17226.1 - 4.3e-33 115.1 0.4 1e-32 113.8 0.0 1.9 2 0 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 OEU17226.1 - 2.3e-18 66.0 0.0 5.7e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 OEU17226.1 - 2.1e-17 63.3 32.0 1.9e-12 47.4 14.8 5.2 5 0 0 5 5 5 2 TAZ zinc finger PHD PF00628.29 OEU17226.1 - 1.9e-08 34.1 6.5 1.9e-08 34.1 6.5 4.1 4 1 1 5 5 5 1 PHD-finger ZZ PF00569.17 OEU17226.1 - 1.4e-05 24.8 6.4 1.4e-05 24.8 6.4 4.2 4 0 0 4 4 4 1 Zinc finger, ZZ type PHD_2 PF13831.6 OEU17226.1 - 0.0023 17.5 3.0 0.01 15.4 3.0 2.3 1 0 0 1 1 1 1 PHD-finger DUF4483 PF14825.6 OEU17226.1 - 0.083 12.6 4.9 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DUF902 PF06001.13 OEU17226.1 - 0.22 12.0 4.5 0.59 10.7 4.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) SET PF00856.28 OEU17227.1 - 2.5e-07 31.2 1.1 8.8e-05 23.0 0.1 3.0 2 1 0 2 2 2 1 SET domain Ephrin_rec_like PF07699.13 OEU17228.1 - 0.026 14.3 10.6 0.079 12.7 6.8 2.9 2 1 0 2 2 2 0 Putative ephrin-receptor like PT PF04886.12 OEU17228.1 - 4 7.1 36.7 1.8e+04 -7.9 36.7 3.1 1 1 0 1 1 1 0 PT repeat TNFR_c6 PF00020.18 OEU17228.1 - 7.8 7.0 11.2 6 7.4 4.3 3.2 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region Dus PF01207.17 OEU17230.1 - 8.1e-28 97.4 0.0 1.1e-27 96.9 0.0 1.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 OEU17230.1 - 0.018 14.3 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme ThiS PF02597.20 OEU17230.1 - 0.038 14.6 0.0 0.092 13.4 0.0 1.6 1 0 0 1 1 1 0 ThiS family EF-hand_1 PF00036.32 OEU17231.1 - 7e-14 50.3 2.2 4.4e-05 22.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OEU17231.1 - 3e-13 50.0 3.1 3.7e-10 40.1 1.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU17231.1 - 2e-12 46.0 3.6 8.4e-05 22.2 0.0 4.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OEU17231.1 - 7.8e-11 41.7 0.9 1.3e-09 37.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU17231.1 - 2.2e-05 23.7 4.1 0.01 15.3 0.1 3.9 3 1 1 4 4 4 2 EF hand EF-hand_11 PF08976.11 OEU17231.1 - 0.00016 22.5 0.3 0.00041 21.2 0.2 1.8 2 0 0 2 2 1 1 EF-hand domain Ion_trans_2 PF07885.16 OEU17231.1 - 0.00093 19.1 14.3 0.011 15.7 1.9 2.9 3 1 0 3 3 3 2 Ion channel S_100 PF01023.19 OEU17231.1 - 0.028 14.1 0.1 0.075 12.8 0.1 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain EF-hand_4 PF12763.7 OEU17231.1 - 0.059 13.3 0.8 0.18 11.8 0.3 2.2 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF489 PF04356.12 OEU17231.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF489) RST PF12174.8 OEU17231.1 - 0.15 12.0 0.0 0.84 9.6 0.0 2.1 1 1 1 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Spermine_synth PF01564.17 OEU17232.1 - 1.7e-13 50.4 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 OEU17232.1 - 0.0002 21.6 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Methyltransf_12 PF08242.12 OEU17232.1 - 0.033 14.9 0.0 0.067 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 OEU17235.1 - 2.3e-19 69.6 0.1 3.4e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 OEU17235.1 - 0.00067 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Methyltransf_25 PF13649.6 OEU17235.1 - 0.021 15.5 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CIDE-N PF02017.15 OEU17235.1 - 0.096 12.7 0.2 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 CIDE-N domain Methyltransf_12 PF08242.12 OEU17235.1 - 0.13 13.0 0.0 0.43 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_99 PF16317.5 OEU17236.1 - 8.7e-09 34.9 0.1 1.1e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 99 DUF1207 PF06727.11 OEU17236.1 - 0.051 12.5 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) EXS PF03124.14 OEU17237.1 - 1.7e-30 106.5 1.0 1.8e-30 106.4 1.0 1.0 1 0 0 1 1 1 1 EXS family EXS PF03124.14 OEU17238.1 - 1.5e-05 24.5 1.8 2.3e-05 23.9 1.8 1.3 1 0 0 1 1 1 1 EXS family Pkinase PF00069.25 OEU17240.1 - 8.5e-30 104.0 0.1 1.2e-29 103.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17240.1 - 6.9e-23 81.2 0.0 9.9e-23 80.7 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.24 OEU17241.1 - 2.3e-96 323.4 22.6 7.5e-96 321.7 22.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU17241.1 - 1.1e-20 73.9 42.9 8.2e-19 67.7 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDZ_6 PF17820.1 OEU17242.1 - 5.8e-05 22.8 0.4 0.00016 21.5 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OEU17242.1 - 0.0048 17.2 0.7 0.011 16.1 0.1 1.8 2 0 0 2 2 2 1 PDZ domain GTP_EFTU PF00009.27 OEU17243.1 - 5.6e-46 156.5 0.0 9.1e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OEU17243.1 - 1.6e-06 28.1 0.0 4.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 OEU17243.1 - 7.7e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 OEU17243.1 - 0.0003 21.1 0.0 0.0033 17.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OEU17243.1 - 0.0045 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OEU17243.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4349 PF14257.6 OEU17243.1 - 0.087 12.3 0.2 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF755 PF05501.11 OEU17243.1 - 0.2 12.0 3.8 0.46 10.8 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 OEU17243.1 - 0.63 9.6 4.3 1.4 8.4 4.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OEU17243.1 - 1.8 9.3 4.5 5.3 7.8 4.5 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1018 PF06252.12 OEU17244.1 - 0.1 13.6 0.8 0.31 12.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) MIR PF02815.19 OEU17245.1 - 8.7e-10 38.7 0.0 2e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 MIR domain CRAL_TRIO PF00650.20 OEU17246.1 - 1.2e-07 31.6 0.0 2.3e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain cNMP_binding PF00027.29 OEU17247.1 - 7.9e-05 22.7 0.0 0.00019 21.4 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Ribosomal_L33 PF00471.20 OEU17250.1 - 6e-11 42.6 0.0 6.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 PsbP PF01789.16 OEU17251.1 - 4.9e-12 46.3 0.2 5.6e-12 46.1 0.2 1.1 1 0 0 1 1 1 1 PsbP E1_UFD PF09358.10 OEU17252.1 - 0.11 13.1 4.1 0.77 10.5 0.0 3.4 3 1 1 4 4 4 0 Ubiquitin fold domain SH2 PF00017.24 OEU17253.1 - 0.18 11.9 2.2 0.68 10.1 2.2 2.1 1 1 0 1 1 1 0 SH2 domain OTU PF02338.19 OEU17254.1 - 8.9e-08 32.7 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OEU17254.1 - 0.01 15.3 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase C65 Otubain PT PF04886.12 OEU17256.1 - 0.0049 16.4 10.8 0.42 10.2 10.8 2.2 1 1 0 1 1 1 1 PT repeat ADH_zinc_N_2 PF13602.6 OEU17257.1 - 7e-08 33.6 0.0 3.2e-06 28.2 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OEU17257.1 - 1.5e-07 31.5 0.1 2.4e-06 27.5 0.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF5510 PF17629.2 OEU17257.1 - 0.11 12.4 1.2 0.36 10.8 1.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Aldo_ket_red PF00248.21 OEU17258.1 - 1.7e-59 201.4 0.0 1.9e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NUMOD3 PF07460.11 OEU17258.1 - 0.13 12.6 0.0 2.5 8.4 0.0 2.7 3 0 0 3 3 3 0 NUMOD3 motif (2 copies) EF-hand_6 PF13405.6 OEU17259.1 - 2.4e-12 45.7 7.9 5.1e-05 22.9 0.0 5.1 5 1 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 OEU17259.1 - 9e-12 43.7 6.8 4.2e-05 22.8 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 OEU17259.1 - 3e-07 30.8 8.4 0.00084 19.7 0.5 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OEU17259.1 - 0.00063 19.1 3.5 0.0017 17.8 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 OEU17259.1 - 0.0024 17.8 6.9 1.4 8.9 0.0 3.6 2 2 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 OEU17259.1 - 0.093 12.6 0.9 1.4 8.8 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair Cytochrom_B562 PF07361.11 OEU17259.1 - 0.3 11.7 6.6 3.2 8.5 0.3 3.1 2 1 0 2 2 2 0 Cytochrome b562 Glyco_hydro_18 PF00704.28 OEU17261.1 - 2.3e-27 96.6 0.0 2.8e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sec23_BS PF08033.12 OEU17262.1 - 6.3e-14 52.5 0.0 1.4e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 OEU17262.1 - 6e-09 35.8 0.0 1.5e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OEU17262.1 - 6.6e-08 32.3 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OEU17262.1 - 5.8e-05 23.1 7.3 0.00014 21.8 7.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OEU17262.1 - 0.003 17.4 0.0 0.0099 15.8 0.0 2.0 1 0 0 1 1 1 1 Gelsolin repeat IR1-M PF12185.8 OEU17263.1 - 0.15 12.1 0.5 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF2721 PF11026.8 OEU17263.1 - 3.6 7.5 6.8 2.8 7.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Bestrophin PF01062.21 OEU17264.1 - 2.5e-12 46.8 6.0 2.1e-06 27.4 0.1 2.5 3 0 0 3 3 3 2 Bestrophin, RFP-TM, chloride channel ATP11 PF06644.11 OEU17265.1 - 0.15 11.8 1.5 0.26 11.0 1.5 1.3 1 0 0 1 1 1 0 ATP11 protein DUF883 PF05957.13 OEU17265.1 - 0.42 11.2 3.1 1.5 9.5 3.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SUIM_assoc PF16619.5 OEU17266.1 - 2.3e-09 37.2 1.4 1.4e+02 2.6 0.0 3.5 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 OEU17266.1 - 0.046 13.7 21.5 0.062 13.3 21.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlaC_arch PF05377.11 OEU17266.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TLD PF07534.16 OEU17267.1 - 2.1e-09 37.7 0.4 8.1e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 TLD SUZ PF12752.7 OEU17268.1 - 2e-10 41.2 5.5 2e-10 41.2 5.5 5.4 4 1 0 4 4 4 1 SUZ domain RCDG1 PF15725.5 OEU17268.1 - 8.5 6.9 9.7 0.5 10.8 2.7 2.7 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein TPR_12 PF13424.6 OEU17269.1 - 7e-31 106.4 3.5 6.8e-16 58.3 0.5 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU17269.1 - 8.7e-15 54.0 2.1 0.0011 18.7 0.1 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU17269.1 - 4.1e-11 42.2 7.1 2.2e-05 24.1 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU17269.1 - 8.5e-11 41.1 2.7 0.00013 21.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU17269.1 - 1e-09 37.8 5.7 0.017 15.3 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OEU17269.1 - 2.6e-06 27.8 0.1 0.19 12.6 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU17269.1 - 0.00011 22.7 2.3 0.1 13.3 0.1 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU17269.1 - 0.00031 21.3 0.0 0.052 14.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU17269.1 - 0.0004 20.2 2.6 0.1 12.7 1.6 3.9 3 1 0 3 3 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU17269.1 - 0.00055 19.3 0.8 0.035 13.6 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_19 PF14559.6 OEU17269.1 - 0.00066 20.1 0.4 0.0063 17.0 0.0 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU17269.1 - 0.001 18.7 9.1 0.84 9.4 0.1 5.0 3 2 2 5 5 5 1 TPR repeat DUF5113 PF17140.4 OEU17269.1 - 0.001 18.9 0.8 0.88 9.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5113) TPR_9 PF13371.6 OEU17269.1 - 0.0044 17.1 0.0 0.53 10.5 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU17269.1 - 0.015 15.5 0.7 0.098 12.9 0.3 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 OEU17269.1 - 0.034 13.6 0.2 0.96 8.9 0.0 2.1 1 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like SNAP PF14938.6 OEU17269.1 - 0.04 13.4 0.1 0.068 12.6 0.1 1.4 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 OEU17269.1 - 0.12 12.4 0.5 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 OEU17269.1 - 0.17 12.3 1.0 13 6.5 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 OEU17270.1 - 1.7e-16 60.2 0.1 3e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SR-25 PF10500.9 OEU17270.1 - 0.51 9.9 7.8 0.82 9.2 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_19 PF14559.6 OEU17271.1 - 5.4e-07 30.0 2.2 0.029 14.9 0.1 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat Suf PF05843.14 OEU17271.1 - 5.6e-05 23.3 3.6 0.0004 20.5 0.7 3.8 2 2 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OEU17271.1 - 0.14 13.0 4.9 58 4.9 0.0 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat Ribosomal_L30 PF00327.20 OEU17272.1 - 1.3e-20 73.0 0.9 2.2e-20 72.3 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 OEU17272.1 - 5.6e-13 48.9 5.8 1.1e-12 48.1 5.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF501 PF04417.12 OEU17273.1 - 1.3e-29 102.7 0.0 2.7e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Proteasome PF00227.26 OEU17274.1 - 2.2e-46 157.7 0.6 2.8e-46 157.4 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit LSM PF01423.22 OEU17275.1 - 2.3e-19 68.8 0.0 2.7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OEU17275.1 - 0.023 14.8 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF1275 PF06912.11 OEU17276.1 - 7.9e-13 48.8 19.4 1.4e-12 48.0 19.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) 2OG-FeII_Oxy PF03171.20 OEU17277.1 - 0.092 13.2 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1242 PF06842.12 OEU17278.1 - 7.1e-15 54.5 1.6 1.1e-14 53.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) UBA PF00627.31 OEU17279.1 - 5.7e-12 45.3 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 OEU17279.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain UBA_3 PF09288.10 OEU17279.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain MAP17 PF15807.5 OEU17279.1 - 0.31 11.3 0.9 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 peroxidase PF00141.23 OEU17280.1 - 1.7e-15 57.3 0.0 3.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Glyco_transf_20 PF00982.21 OEU17281.1 - 2.7e-99 333.0 0.0 3.9e-99 332.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OEU17281.1 - 2.8e-33 115.0 0.0 6.3e-33 113.8 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase adh_short PF00106.25 OEU17283.1 - 7.4e-18 64.7 0.0 8.8e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17283.1 - 1.2e-11 44.6 0.0 1.6e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU17283.1 - 1.5e-06 28.3 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OEU17283.1 - 0.00036 20.0 0.5 0.00064 19.2 0.1 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) HEPN_LA2681 PF18733.1 OEU17283.1 - 0.12 11.7 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 LA2681-like HEPN DUF1771 PF08590.10 OEU17285.1 - 2.1e-14 53.6 2.1 7.7e-14 51.8 2.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 OEU17285.1 - 3.3e-12 46.6 0.2 7.1e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Smr domain Exostosin PF03016.15 OEU17285.1 - 0.0012 18.1 0.5 0.0015 17.8 0.5 1.1 1 0 0 1 1 1 1 Exostosin family DUF2947 PF11163.8 OEU17285.1 - 0.043 13.7 1.6 0.06 13.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DnaJ PF00226.31 OEU17287.1 - 4.4e-11 42.7 0.0 6.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Mucin-like PF16058.5 OEU17287.1 - 0.34 11.0 5.3 0.52 10.4 5.3 1.2 1 0 0 1 1 1 0 Mucin-like Alanine_zipper PF11839.8 OEU17288.1 - 0.028 14.8 22.5 0.5 10.8 5.1 2.2 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein MFS_1 PF07690.16 OEU17289.1 - 2e-33 115.8 15.5 2.8e-18 66.0 1.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU17289.1 - 1.5e-11 43.8 17.1 3.7e-11 42.5 17.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OEU17289.1 - 0.12 10.8 4.4 0.043 12.2 0.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Rotamase_3 PF13616.6 OEU17290.1 - 7.6e-22 78.0 0.0 1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OEU17290.1 - 9.4e-21 74.6 0.0 1.5e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU17290.1 - 2.4e-05 25.1 0.0 3.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF3439 PF11921.8 OEU17290.1 - 0.0084 16.1 1.8 0.013 15.5 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 OEU17290.1 - 0.083 10.9 0.4 0.082 10.9 0.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.11 OEU17290.1 - 0.15 12.0 2.4 0.19 11.7 2.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Spectrin PF00435.21 OEU17291.1 - 0.014 15.9 1.1 0.037 14.5 1.1 1.7 1 0 0 1 1 1 0 Spectrin repeat DUF2524 PF10732.9 OEU17291.1 - 0.22 11.8 4.0 0.31 11.4 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Secretin_N_2 PF07655.13 OEU17291.1 - 0.35 11.4 7.3 15 6.2 4.2 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain NAD_binding_8 PF13450.6 OEU17292.1 - 2e-09 37.5 0.2 5.9e-09 36.0 0.2 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU17292.1 - 1.1e-05 25.2 0.7 1.8e-05 24.5 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OEU17292.1 - 1.6e-05 24.4 0.0 0.00079 18.8 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OEU17292.1 - 0.00055 19.3 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TFIIA PF03153.13 OEU17293.1 - 0.0027 17.8 13.9 0.0086 16.1 13.9 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF676 PF05057.14 OEU17294.1 - 4.1e-25 88.6 0.6 1.5e-23 83.5 0.6 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OEU17294.1 - 0.032 14.0 0.3 0.064 13.0 0.3 1.5 1 0 0 1 1 1 0 PGAP1-like protein CAC1F_C PF16885.5 OEU17295.1 - 0.13 11.9 9.6 0.22 11.1 9.6 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF5426 PF17473.2 OEU17295.1 - 1 9.6 3.3 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5426) Tristanin_u2 PF16638.5 OEU17295.1 - 5.4 7.9 7.5 2.4 9.0 2.1 2.5 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers AIF_C PF14721.6 OEU17295.1 - 7.8 6.9 12.1 29 5.0 0.0 3.7 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3439 PF11921.8 OEU17296.1 - 0.0025 17.8 9.5 0.0054 16.7 9.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Toxin_10 PF05431.11 OEU17296.1 - 0.029 13.8 3.8 0.17 11.3 0.0 2.5 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 Cytomega_gL PF01801.16 OEU17296.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L Tmemb_cc2 PF10267.9 OEU17297.1 - 0.12 11.5 5.3 0.15 11.2 5.3 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Trp_Tyr_perm PF03222.13 OEU17299.1 - 1.3e-38 133.1 17.4 4.2e-28 98.5 13.3 2.1 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 OEU17299.1 - 0.0037 16.0 7.2 0.0081 14.9 7.2 1.6 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAM76 PF16046.5 OEU17300.1 - 0.015 14.6 0.7 0.015 14.6 0.7 2.1 3 0 0 3 3 3 0 FAM76 protein Helitron_like_N PF14214.6 OEU17304.1 - 5.3e-12 46.3 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SIR2 PF02146.17 OEU17304.1 - 0.025 14.5 2.6 3.3 7.6 2.6 2.6 1 1 0 1 1 1 0 Sir2 family Fasciclin PF02469.22 OEU17305.1 - 1.7e-15 57.3 0.0 2.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain TMIE PF16038.5 OEU17305.1 - 1.1 9.2 4.9 2.3 8.1 4.9 1.5 1 0 0 1 1 1 0 TMIE protein Spermine_synth PF01564.17 OEU17307.1 - 9.8e-12 44.7 0.0 1.7e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 OEU17307.1 - 0.16 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Pcc1 PF09341.10 OEU17308.1 - 5.5e-16 58.5 0.0 8.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 LRR_4 PF12799.7 OEU17309.1 - 8e-08 32.5 22.1 0.015 15.7 0.0 7.6 7 0 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU17309.1 - 1.2e-06 28.0 22.7 0.82 9.9 0.1 10.1 10 0 0 10 10 10 2 Leucine Rich repeat LRR_8 PF13855.6 OEU17309.1 - 0.0031 17.2 16.5 1.6 8.6 0.0 7.1 6 1 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 OEU17309.1 - 0.18 12.4 21.8 1.3e+02 3.8 0.0 10.6 11 1 0 11 11 11 0 Leucine Rich Repeat O-FucT PF10250.9 OEU17310.1 - 1.2e-47 163.2 0.2 1.7e-47 162.7 0.2 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Flagellar_rod PF05149.12 OEU17310.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein MORN PF02493.20 OEU17311.1 - 2.2e-20 71.3 34.7 1.5e-06 27.7 1.2 7.0 6 2 0 6 6 6 6 MORN repeat DEAD PF00270.29 OEU17312.1 - 3.5e-42 144.1 0.0 8e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU17312.1 - 1.5e-25 89.7 0.0 3.8e-24 85.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OEU17312.1 - 9.8e-10 38.5 0.0 3.5e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OEU17312.1 - 2.8e-06 27.4 0.1 7.8e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Aldedh PF00171.22 OEU17313.1 - 1.9e-05 23.4 0.2 0.0018 16.9 0.0 3.1 3 1 0 3 3 3 3 Aldehyde dehydrogenase family Pex14_N PF04695.13 OEU17315.1 - 3 8.5 11.1 3 8.5 9.6 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4092 PF13322.6 OEU17316.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) PAP2 PF01569.21 OEU17317.1 - 2.2e-26 92.2 4.3 2.5e-26 92.1 4.3 1.0 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OEU17317.1 - 9.1e-05 22.2 6.6 0.027 14.2 6.6 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 OEU17317.1 - 0.02 15.0 1.4 0.29 11.3 0.2 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF1980 PF09323.10 OEU17317.1 - 0.098 12.6 0.6 0.15 11.9 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Cdc6_C PF09079.11 OEU17318.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF563 PF04577.14 OEU17319.1 - 1.7e-05 25.0 0.0 3.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) O-FucT PF10250.9 OEU17320.1 - 1.1e-54 186.5 0.4 1.3e-54 186.2 0.4 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Choline_transpo PF04515.12 OEU17321.1 - 4.2e-69 233.2 31.3 4.2e-69 233.2 31.3 2.4 1 1 1 2 2 2 1 Plasma-membrane choline transporter BRCA-2_OB1 PF09103.10 OEU17322.1 - 2.6e-30 104.9 0.0 4.2e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 OEU17322.1 - 3.1e-12 46.5 0.0 5.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical Terpene_synth_C PF03936.16 OEU17322.1 - 0.041 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Methyltransf_25 PF13649.6 OEU17324.1 - 2e-18 66.8 0.0 2.9e-09 37.5 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OEU17324.1 - 4.7e-18 65.6 0.0 3.9e-16 59.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU17324.1 - 2.8e-16 59.5 0.1 2e-13 50.2 0.1 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU17324.1 - 6.8e-11 42.2 0.0 5.1e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU17324.1 - 1.7e-10 41.0 0.0 2.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU17324.1 - 4e-10 40.3 0.0 9.4e-09 35.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU17324.1 - 2.2e-05 24.0 0.1 0.017 14.7 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Rsm22 PF09243.10 OEU17324.1 - 0.00031 20.1 0.0 0.016 14.5 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_2 PF00891.18 OEU17324.1 - 0.01 15.1 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_4 PF02390.17 OEU17324.1 - 0.05 13.1 0.0 3.9 6.9 0.0 2.7 2 1 1 3 3 3 0 Putative methyltransferase HA PF03457.14 OEU17325.1 - 9.4e-31 106.0 4.9 3.2e-17 62.6 0.1 2.1 2 0 0 2 2 2 2 Helicase associated domain Thioredoxin_6 PF13848.6 OEU17325.1 - 0.13 12.2 0.4 1.5 8.7 0.1 2.0 1 1 0 2 2 2 0 Thioredoxin-like domain Melittin PF01372.17 OEU17325.1 - 2.4 8.3 7.5 13 5.9 0.7 2.4 2 0 0 2 2 2 0 Melittin Choline_transpo PF04515.12 OEU17326.1 - 5.6e-41 140.8 0.6 7.4e-41 140.4 0.6 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter Acatn PF13000.7 OEU17326.1 - 0.0067 15.0 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 DUF543 PF04418.12 OEU17326.1 - 1.3 9.0 3.8 2 8.5 0.0 3.1 4 1 1 5 5 5 0 Domain of unknown function (DUF543) Tfb5 PF06331.12 OEU17327.1 - 7.2e-21 73.9 0.0 1.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Autophagy_N PF03986.13 OEU17327.1 - 0.064 13.2 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Aldedh PF00171.22 OEU17328.1 - 9.7e-148 492.5 0.3 1.2e-147 492.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OEU17328.1 - 0.0033 16.9 0.1 0.014 14.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Herpes_UL46 PF03387.14 OEU17329.1 - 0.094 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein Tudor_2 PF18104.1 OEU17330.1 - 0.00028 20.5 0.2 0.00054 19.6 0.2 1.5 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Cwf_Cwc_15 PF04889.12 OEU17330.1 - 0.13 12.0 3.8 0.2 11.4 3.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF962 PF06127.11 OEU17331.1 - 1.1 9.4 3.1 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Exostosin PF03016.15 OEU17333.1 - 2.5e-10 40.1 0.1 1.2e-07 31.2 0.0 2.5 2 1 0 2 2 2 2 Exostosin family Nup35_RRM PF05172.13 OEU17334.1 - 0.00049 20.0 0.0 0.0033 17.3 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OEU17334.1 - 0.006 16.6 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_S49 PF01343.18 OEU17335.1 - 3.1e-32 111.7 0.0 3.6e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 OEU17335.1 - 0.0014 17.7 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 OEU17335.1 - 0.018 15.0 1.4 1.1 9.1 1.4 2.5 1 1 0 1 1 1 0 Clp protease Peptidase_S49_N PF08496.10 OEU17335.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal POTRA_2 PF08479.11 OEU17336.1 - 0.00043 20.1 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 POTRA domain, ShlB-type POTRA PF07244.15 OEU17336.1 - 0.0064 17.1 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 2 Surface antigen variable number repeat adh_short_C2 PF13561.6 OEU17337.1 - 5.8e-33 114.4 0.1 6.7e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU17337.1 - 2.3e-22 79.4 0.1 2.9e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU17337.1 - 7.5e-07 29.2 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OEU17337.1 - 0.00023 21.1 0.1 0.00049 20.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OEU17337.1 - 0.00036 20.1 0.0 0.00042 19.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OEU17337.1 - 0.0041 16.3 0.1 0.0066 15.6 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein WD40 PF00400.32 OEU17338.1 - 2.8e-11 43.8 4.1 0.0025 18.6 0.2 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU17338.1 - 4.4e-11 42.9 0.0 0.00041 20.6 0.0 5.1 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OEU17338.1 - 0.00016 21.5 0.0 0.44 10.6 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Spt5_N PF11942.8 OEU17338.1 - 0.0004 21.3 6.5 0.0004 21.3 6.5 1.7 1 1 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Ge1_WD40 PF16529.5 OEU17338.1 - 0.0059 15.6 0.3 3.6 6.5 0.1 4.0 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OEU17338.1 - 0.012 15.0 0.2 0.042 13.2 0.1 1.8 2 0 0 2 2 2 0 WD40-like domain PEHE PF15275.6 OEU17338.1 - 1.1 9.9 7.0 0.12 13.0 2.5 1.7 2 0 0 2 2 2 0 PEHE domain Ribosomal_S25 PF03297.15 OEU17339.1 - 3.6e-38 129.8 2.7 4e-38 129.7 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 OEU17339.1 - 0.04 13.5 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EAP30 PF04157.16 OEU17339.1 - 0.042 13.1 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Macoilin PF09726.9 OEU17340.1 - 0.32 9.5 34.7 0.42 9.1 34.7 1.3 1 0 0 1 1 1 0 Macoilin family Med22 PF06179.12 OEU17341.1 - 4e-06 27.0 1.1 2.4e-05 24.5 1.1 1.9 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PAP_fibrillin PF04755.12 OEU17342.1 - 1.2e-05 25.4 0.1 0.00012 22.0 0.1 2.2 1 1 0 1 1 1 1 PAP_fibrillin AAA PF00004.29 OEU17343.1 - 1.1e-96 320.3 0.0 6.6e-47 159.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU17343.1 - 3.9e-26 90.6 7.5 1e-14 54.1 0.9 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OEU17343.1 - 8.2e-19 67.6 1.9 1.2e-18 67.1 0.8 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OEU17343.1 - 5.1e-14 52.3 0.0 1.9e-05 24.5 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 OEU17343.1 - 6.4e-14 51.5 0.0 1.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 OEU17343.1 - 1.5e-12 48.0 0.0 1e-05 25.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OEU17343.1 - 2.7e-12 47.4 2.1 0.00025 21.5 0.0 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 OEU17343.1 - 1.3e-10 41.6 0.0 5.9e-05 23.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OEU17343.1 - 4.2e-10 39.8 0.0 6.3e-05 23.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU17343.1 - 6.7e-10 39.4 0.1 0.022 15.0 0.0 4.6 3 2 1 4 4 4 2 AAA domain TIP49 PF06068.13 OEU17343.1 - 5.5e-08 32.4 0.0 0.00076 18.8 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 OEU17343.1 - 1e-07 32.0 0.0 0.0065 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU17343.1 - 5e-07 30.1 0.0 0.015 15.7 0.0 3.2 3 1 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 OEU17343.1 - 5.5e-07 30.2 0.0 0.043 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OEU17343.1 - 1.1e-06 28.2 0.3 0.059 12.7 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 OEU17343.1 - 1e-05 25.4 0.6 0.0017 18.3 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 OEU17343.1 - 1e-05 25.3 0.1 0.24 11.1 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 OEU17343.1 - 1.5e-05 24.6 0.0 0.089 12.3 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 OEU17343.1 - 1.7e-05 25.2 0.8 0.092 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 OEU17343.1 - 2.7e-05 24.7 0.0 0.15 12.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ATPase_2 PF01637.18 OEU17343.1 - 2.7e-05 24.2 0.0 0.28 11.1 0.0 3.2 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OEU17343.1 - 3.2e-05 23.6 0.2 1.6 8.3 0.0 3.6 2 1 0 3 3 3 1 AAA domain ATPase PF06745.13 OEU17343.1 - 3.2e-05 23.4 0.1 2 7.7 0.0 3.5 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.6 OEU17343.1 - 8.3e-05 22.9 0.1 0.51 10.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 OEU17343.1 - 8.3e-05 22.4 0.0 0.014 15.1 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OEU17343.1 - 0.0001 21.6 0.1 0.99 8.5 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain AAA_24 PF13479.6 OEU17343.1 - 0.00011 22.0 0.0 0.18 11.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 OEU17343.1 - 0.00012 22.0 0.0 0.6 10.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 OEU17343.1 - 0.00017 21.5 0.0 0.22 11.3 0.0 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein NACHT PF05729.12 OEU17343.1 - 0.00018 21.5 0.0 2.8 7.9 0.0 3.7 3 1 0 4 4 3 1 NACHT domain Sigma54_activat PF00158.26 OEU17343.1 - 0.00019 21.2 0.0 0.85 9.3 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 OEU17343.1 - 0.00021 21.4 0.1 0.14 12.3 0.0 2.9 3 0 0 3 3 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.17 OEU17343.1 - 0.00023 20.3 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 OEU17343.1 - 0.0004 19.7 0.0 0.69 9.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.6 OEU17343.1 - 0.00041 20.5 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 OEU17343.1 - 0.0006 19.9 0.0 0.095 12.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 OEU17343.1 - 0.0014 18.6 0.0 0.57 10.1 0.0 3.1 3 1 0 3 3 3 1 Rad17 P-loop domain AAA_3 PF07726.11 OEU17343.1 - 0.0014 18.5 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OEU17343.1 - 0.0015 17.7 0.0 0.34 10.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 OEU17343.1 - 0.003 17.0 0.2 3.3 7.1 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 OEU17343.1 - 0.0048 16.7 0.1 3.1 7.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OEU17343.1 - 0.0057 16.6 0.6 4.6 7.1 0.0 3.8 3 1 1 4 4 4 0 NTPase DUF2075 PF09848.9 OEU17343.1 - 0.0057 15.9 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UFD1 PF03152.14 OEU17343.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_19 PF13245.6 OEU17343.1 - 0.0092 16.3 1.5 7.1 6.9 0.1 3.6 3 1 1 4 4 3 0 AAA domain AAA_30 PF13604.6 OEU17343.1 - 0.01 15.5 0.1 6.7 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 OEU17343.1 - 0.032 14.4 0.6 12 6.0 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase Cytidylate_kin PF02224.18 OEU17343.1 - 0.042 13.6 0.0 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 OEU17343.1 - 0.044 13.4 0.0 1.4 8.5 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Molydop_binding PF01568.21 OEU17343.1 - 0.077 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 1 0 Molydopterin dinucleotide binding domain KAP_NTPase PF07693.14 OEU17343.1 - 0.087 12.0 0.2 3.2 6.9 0.0 3.0 2 2 2 4 4 4 0 KAP family P-loop domain AAA_29 PF13555.6 OEU17343.1 - 0.097 12.4 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 OEU17343.1 - 0.13 11.7 0.0 15 4.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein Sulfotransfer_3 PF13469.6 OEU17344.1 - 0.091 13.1 0.3 0.75 10.1 0.1 2.2 1 1 1 2 2 2 0 Sulfotransferase family PPR_1 PF12854.7 OEU17345.1 - 4.9e-11 42.1 0.0 2.4e-07 30.3 0.0 3.6 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 OEU17345.1 - 8.7e-10 38.6 1.9 0.00011 22.3 0.0 4.5 5 1 0 5 5 5 2 PPR repeat family PPR PF01535.20 OEU17345.1 - 8.7e-09 35.1 3.2 0.0012 18.9 0.0 5.2 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 OEU17345.1 - 1.3e-06 28.4 0.1 0.028 14.5 0.0 3.6 2 1 1 3 3 3 2 Pentatricopeptide repeat domain TPR_MalT PF17874.1 OEU17345.1 - 0.0013 18.2 4.0 0.22 10.9 0.0 2.7 2 1 1 3 3 3 2 MalT-like TPR region TPR_12 PF13424.6 OEU17345.1 - 0.073 13.4 1.4 0.88 9.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 OEU17346.1 - 4.8e-66 218.7 2.7 1.1e-21 76.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1450 PF07293.11 OEU17347.1 - 0.079 12.8 0.8 0.13 12.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) 2Fe-2S_thioredx PF01257.19 OEU17347.1 - 0.16 11.9 2.5 0.37 10.6 2.4 1.6 1 1 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin PHINT_rpt PF14882.6 OEU17348.1 - 0.04 14.2 0.2 0.04 14.2 0.2 2.0 1 1 1 2 2 2 0 Phage-integrase repeat unit DUF111 PF01969.17 OEU17349.1 - 1.2e-62 212.1 8.8 9e-62 209.3 8.8 2.2 1 1 0 1 1 1 1 Protein of unknown function DUF111 SPX PF03105.19 OEU17349.1 - 0.0045 17.0 1.7 0.0047 16.9 1.7 1.1 1 0 0 1 1 1 1 SPX domain Zip PF02535.22 OEU17349.1 - 0.3 10.3 7.0 0.4 9.9 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 OEU17349.1 - 3 7.1 6.5 4.1 6.7 6.5 1.1 1 0 0 1 1 1 0 FAM76 protein HMG_box PF00505.19 OEU17352.1 - 0.087 13.2 0.9 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box VWA_2 PF13519.6 OEU17353.1 - 0.042 14.5 0.1 16 6.2 0.0 2.7 3 0 0 3 3 3 0 von Willebrand factor type A domain PSD3 PF07626.11 OEU17353.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) BTB PF00651.31 OEU17354.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain 2-Hacid_dh_C PF02826.19 OEU17356.1 - 1.1e-44 151.9 0.0 1.9e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OEU17356.1 - 5.4e-24 84.4 0.0 6.3e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OEU17356.1 - 7.5e-07 29.4 0.0 2.7e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 OEU17356.1 - 0.044 13.8 0.2 0.097 12.7 0.2 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 OEU17356.1 - 0.066 12.8 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 OEU17356.1 - 0.086 12.4 0.4 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.19 OEU17357.1 - 2.5e-12 46.4 0.5 8.7e-10 38.1 0.0 2.9 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OEU17357.1 - 8.8e-06 26.0 0.1 1.7e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RRM_1 PF00076.22 OEU17358.1 - 5.1e-17 61.5 0.0 7.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU17358.1 - 1.7e-06 27.7 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 OEU17359.1 - 2.8e-20 72.6 0.0 3.4e-17 62.6 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17359.1 - 4.3e-13 49.4 0.0 2.5e-08 33.8 0.0 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase CPSF100_C PF13299.6 OEU17359.1 - 0.094 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4611 PF15387.6 OEU17359.1 - 0.49 10.7 4.0 1.1 9.5 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FA_desaturase PF00487.24 OEU17361.1 - 2.3e-38 132.5 15.3 2.3e-38 132.5 15.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OEU17361.1 - 4.9e-05 23.4 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spermine_synth PF01564.17 OEU17362.1 - 2.3e-50 170.6 0.0 4.1e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OEU17362.1 - 2.3e-12 46.6 0.6 4.5e-12 45.7 0.6 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OEU17362.1 - 5.5e-05 23.8 0.0 0.00027 21.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU17362.1 - 0.041 14.6 0.0 0.079 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain QVR PF17064.5 OEU17362.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Sleepless protein Nop14 PF04147.12 OEU17363.1 - 1.1e-133 447.5 26.2 1.4e-133 447.1 26.2 1.0 1 0 0 1 1 1 1 Nop14-like family Agenet PF05641.12 OEU17363.1 - 1.5e-05 25.4 1.0 0.00047 20.6 0.1 3.2 2 0 0 2 2 2 1 Agenet domain TUDOR_5 PF18359.1 OEU17363.1 - 4.2e-05 23.2 0.5 0.0001 21.9 0.5 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DHHC PF01529.20 OEU17364.1 - 1.9e-31 109.0 3.4 2.6e-31 108.5 3.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase EcsB PF05975.12 OEU17364.1 - 0.0013 17.7 0.9 0.0016 17.4 0.9 1.0 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB PsaX PF08078.12 OEU17364.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 PsaX family Choline_transpo PF04515.12 OEU17366.1 - 1.9e-52 178.5 20.2 1.9e-52 178.5 20.2 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF3446 PF11928.8 OEU17369.1 - 5.5 7.4 11.9 1.4 9.3 7.5 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain ExbD PF02472.16 OEU17372.1 - 0.0071 16.5 2.4 0.017 15.3 2.4 1.6 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR Hexapep PF00132.24 OEU17372.1 - 0.095 12.5 0.2 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) GNAT_acetyltr_2 PF13718.6 OEU17372.1 - 0.095 12.1 0.8 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF848 PF05852.11 OEU17372.1 - 0.29 11.2 4.3 0.48 10.5 3.0 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CMD PF02627.20 OEU17373.1 - 9.4e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Mito_carr PF00153.27 OEU17374.1 - 1.2e-21 76.4 1.9 7.3e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein FAST_1 PF06743.15 OEU17375.1 - 8e-06 25.7 0.1 0.064 13.2 0.0 3.7 3 1 0 3 3 3 3 FAST kinase-like protein, subdomain 1 DUF1601 PF07671.11 OEU17375.1 - 1.1 9.2 3.7 1.1 9.1 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) DUF603 PF04645.12 OEU17376.1 - 0.089 12.5 3.0 0.31 10.7 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF603 HSF_DNA-bind PF00447.17 OEU17377.1 - 6.7e-09 36.2 0.9 0.00028 21.4 0.1 2.5 1 1 1 2 2 2 2 HSF-type DNA-binding GOLGA2L5 PF15070.6 OEU17377.1 - 0.00065 18.5 0.4 0.00083 18.1 0.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Nup54 PF13874.6 OEU17377.1 - 0.017 15.3 1.1 1.1 9.4 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Cnn_1N PF07989.11 OEU17377.1 - 0.017 15.3 0.2 0.034 14.3 0.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF4709 PF15821.5 OEU17377.1 - 0.018 15.3 0.4 0.034 14.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) DEAD PF00270.29 OEU17378.1 - 1e-19 71.0 0.2 1.3e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU17378.1 - 9.4e-17 61.4 0.0 2.1e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OEU17378.1 - 4.1e-08 33.8 1.8 6.5e-08 33.2 0.6 2.0 2 0 0 2 2 2 1 RecQ zinc-binding Flavodoxin_5 PF12724.7 OEU17378.1 - 0.0093 16.2 0.3 0.037 14.3 0.5 1.9 2 0 0 2 2 2 1 Flavodoxin domain GTP_cyclohydroI PF01227.22 OEU17378.1 - 0.012 15.0 0.5 0.024 14.1 0.5 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I ResIII PF04851.15 OEU17378.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PAC4 PF16093.5 OEU17378.1 - 0.15 12.3 0.1 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 ubiquitin PF00240.23 OEU17379.1 - 2.1e-34 117.1 0.7 2.3e-34 117.0 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU17379.1 - 2.1e-16 59.5 0.9 2.3e-16 59.4 0.9 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU17379.1 - 5.3e-06 26.8 0.2 2.1e-05 24.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU17379.1 - 0.0013 18.6 0.1 0.0014 18.5 0.1 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU17379.1 - 0.0017 18.3 0.3 1.8 8.7 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OEU17379.1 - 0.0026 18.1 0.1 0.0032 17.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU17379.1 - 0.0035 17.4 0.1 0.0072 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OEU17379.1 - 0.0099 16.4 0.1 0.011 16.3 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OEU17379.1 - 0.06 13.2 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain SMC_N PF02463.19 OEU17380.1 - 4.7e-20 72.0 36.2 1.2e-19 70.6 36.3 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU17380.1 - 8.1e-09 35.7 6.0 0.00039 20.3 0.2 3.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OEU17380.1 - 3.9e-08 33.4 5.1 3.9e-08 33.4 5.1 4.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 OEU17380.1 - 4.1e-05 23.2 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OEU17380.1 - 0.00036 21.1 45.5 0.00036 21.1 45.5 6.3 2 2 1 3 3 3 1 AAA domain EzrA PF06160.12 OEU17380.1 - 0.0016 16.7 25.5 0.0016 16.7 25.5 5.3 3 1 1 5 5 5 3 Septation ring formation regulator, EzrA SbcCD_C PF13558.6 OEU17380.1 - 0.007 16.6 0.0 0.026 14.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Bap31_Bap29_C PF18035.1 OEU17380.1 - 0.0085 16.1 5.8 0.0085 16.1 5.8 5.0 4 1 1 5 5 5 1 Bap31/Bap29 cytoplasmic coiled-coil domain ABC_tran PF00005.27 OEU17380.1 - 0.87 10.1 0.0 0.87 10.1 0.0 5.3 3 2 0 3 3 3 0 ABC transporter DDE_Tnp_4 PF13359.6 OEU17382.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease AUX_IAA PF02309.16 OEU17382.1 - 0.084 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AUX/IAA family PHD PF00628.29 OEU17385.1 - 1.6e-10 40.7 36.1 7.2e-06 25.8 12.7 3.4 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 OEU17385.1 - 0.0086 15.6 1.9 0.0086 15.6 1.9 3.0 3 0 0 3 3 3 2 PHD-finger Rubredoxin PF00301.20 OEU17385.1 - 0.27 11.3 5.3 9.9 6.3 0.7 3.1 2 0 0 2 2 2 0 Rubredoxin AT_hook PF02178.19 OEU17385.1 - 0.53 10.3 41.8 0.63 10.1 7.4 5.3 4 0 0 4 4 4 0 AT hook motif AFP_2 PF18815.1 OEU17385.1 - 0.55 10.5 2.9 1.8 8.9 2.9 1.8 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat DUF3761 PF12587.8 OEU17386.1 - 0.16 12.4 0.1 0.19 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) GILT PF03227.16 OEU17387.1 - 3.5e-12 46.5 0.4 3.8e-11 43.2 0.4 2.3 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) HOCHOB PF17943.1 OEU17387.1 - 0.02 15.6 0.1 0.03 15.0 0.1 1.3 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox Thioredoxin_4 PF13462.6 OEU17387.1 - 0.096 12.8 0.1 1.4 9.1 0.0 2.1 1 1 0 2 2 2 0 Thioredoxin HhH-GPD PF00730.25 OEU17388.1 - 4.5e-05 23.9 0.0 8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ABC2_membrane PF01061.24 OEU17389.1 - 2.8e-29 102.1 15.8 2.8e-29 102.1 15.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OEU17389.1 - 9.9e-25 87.6 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU17389.1 - 3e-11 43.7 0.0 0.00026 20.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU17389.1 - 1.8e-06 27.6 0.0 2.1e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OEU17389.1 - 7.6e-06 25.6 0.1 1.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU17389.1 - 0.00028 20.8 0.2 0.00053 19.9 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 OEU17389.1 - 0.0006 19.0 23.8 0.0006 19.0 23.8 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 OEU17389.1 - 0.00061 20.2 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OEU17389.1 - 0.0011 19.5 0.1 0.0028 18.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU17389.1 - 0.0014 18.9 0.1 0.0058 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OEU17389.1 - 0.0043 16.7 0.0 0.07 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU17389.1 - 0.006 17.1 0.0 0.012 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU17389.1 - 0.016 15.4 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OEU17389.1 - 0.083 12.6 0.2 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OEU17389.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 OEU17389.1 - 0.085 12.6 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 OEU17389.1 - 0.12 12.0 0.2 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OEU17389.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 OEU17389.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OEU17389.1 - 0.18 11.7 0.8 0.42 10.5 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Na_H_Exchanger PF00999.21 OEU17390.1 - 1.9e-49 168.5 33.1 2.5e-49 168.1 33.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 OEU17390.1 - 2.3e-14 53.6 0.0 4.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain EF-hand_1 PF00036.32 OEU17390.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OEU17390.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 OEU17390.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair 2-Hacid_dh_C PF02826.19 OEU17390.1 - 0.19 11.1 0.0 0.71 9.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2615 PF11027.8 OEU17391.1 - 0.002 18.2 0.4 2.2 8.4 0.1 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2615) Tetraspanin PF00335.20 OEU17391.1 - 0.032 14.0 0.8 0.032 14.0 0.8 2.8 1 1 1 2 2 2 0 Tetraspanin family DUF2427 PF10348.9 OEU17391.1 - 0.056 13.2 1.2 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4834 PF16118.5 OEU17391.1 - 0.078 13.9 1.3 3.5 8.7 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1673 PF07895.11 OEU17391.1 - 0.082 12.6 3.2 0.094 12.4 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) MIG-14_Wnt-bd PF06664.12 OEU17391.1 - 1.1 8.4 8.7 3.9 6.6 0.1 2.3 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion G6PD_C PF02781.16 OEU17392.1 - 4.4e-92 308.4 0.0 6.2e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OEU17392.1 - 1.3e-55 188.8 0.0 1.9e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Thioredoxin PF00085.20 OEU17394.1 - 5e-09 36.1 0.0 7.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 OEU17394.1 - 4.4e-06 25.9 0.1 5.3e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Phosducin Methyltransf_4 PF02390.17 OEU17395.1 - 1e-48 165.1 0.0 1.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OEU17395.1 - 2.5e-06 28.1 0.0 4.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU17395.1 - 6.6e-06 25.8 0.0 4.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OEU17395.1 - 0.00029 21.4 0.0 0.0011 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU17395.1 - 0.0014 19.3 0.0 0.0046 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU17395.1 - 0.0018 18.3 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU17395.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OEU17395.1 - 0.013 15.3 0.0 0.081 12.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OEU17395.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 OEU17395.1 - 0.18 11.1 0.0 0.51 9.7 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_S28 PF05577.12 OEU17396.1 - 9.5e-60 202.6 0.3 1.8e-59 201.7 0.3 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 TrbE PF11100.8 OEU17397.1 - 0.16 12.2 3.1 7.1 6.9 0.1 2.8 2 1 1 3 3 3 0 Conjugal transfer protein TrbE MotA_ExbB PF01618.16 OEU17397.1 - 0.67 9.7 2.9 1.2 8.9 2.9 1.5 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family TENA_THI-4 PF03070.16 OEU17399.1 - 1.4e-06 28.3 0.0 1.7e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DUF3677 PF12432.8 OEU17400.1 - 6.8e-08 32.7 0.4 4.5e-06 26.9 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) RsbRD_N PF14361.6 OEU17400.1 - 0.023 15.4 0.2 1.2 9.9 0.0 3.9 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Trm112p PF03966.16 OEU17401.1 - 9.5e-10 38.9 0.0 1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein adh_short PF00106.25 OEU17402.1 - 8.5e-49 165.7 0.1 1e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17402.1 - 6.3e-35 120.8 0.1 9.5e-35 120.2 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU17402.1 - 6.4e-16 58.8 0.0 8.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU17402.1 - 1.4e-05 24.7 0.0 0.0002 20.9 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU17402.1 - 0.011 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase IMD PF08397.11 OEU17404.1 - 0.033 13.6 1.0 0.66 9.3 0.2 2.4 2 0 0 2 2 2 0 IRSp53/MIM homology domain GST_N_3 PF13417.6 OEU17407.1 - 3.5e-12 46.5 0.0 7.6e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU17407.1 - 3.2e-11 43.4 0.0 6.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU17407.1 - 2.4e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU17407.1 - 6.2e-06 26.5 0.0 3.1e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU17407.1 - 9.4e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU17407.1 - 0.00036 20.7 0.0 0.00097 19.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OEU17407.1 - 0.00045 20.8 0.0 0.00076 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OEU17407.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Myb_DNA-binding PF00249.31 OEU17410.1 - 8.5e-33 112.3 2.6 9e-12 45.0 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU17410.1 - 1.2e-26 92.7 0.4 5.9e-10 39.3 0.0 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU17410.1 - 3.6e-05 23.6 0.2 0.00061 19.6 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OEU17410.1 - 0.00023 21.2 0.3 2.7 8.2 0.1 3.5 2 1 1 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 OEU17410.1 - 0.00073 19.6 0.0 0.62 10.2 0.0 2.6 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OEU17410.1 - 0.032 14.2 0.1 0.95 9.5 0.0 2.3 1 1 0 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 OEU17410.1 - 0.049 14.0 1.8 0.072 13.5 0.1 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OEU17410.1 - 0.17 12.1 0.5 0.77 10.0 0.0 2.3 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 zf-A20 PF01754.16 OEU17411.1 - 6.2e-08 32.4 9.5 9.8e-08 31.8 9.5 1.3 1 0 0 1 1 1 1 A20-like zinc finger SR-25 PF10500.9 OEU17411.1 - 0.0019 17.8 9.7 0.0026 17.4 9.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tir_receptor_C PF07489.11 OEU17411.1 - 0.0031 17.5 7.2 0.0037 17.3 7.2 1.2 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.17 OEU17411.1 - 0.0049 16.9 17.8 0.0075 16.3 17.8 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Presenilin PF01080.17 OEU17411.1 - 0.037 12.8 1.2 0.052 12.3 1.2 1.2 1 0 0 1 1 1 0 Presenilin ASD2 PF08687.11 OEU17411.1 - 0.21 11.1 5.4 0.27 10.8 5.4 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Ndc1_Nup PF09531.10 OEU17411.1 - 0.54 8.9 6.2 0.64 8.6 6.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Guanylate_cyc PF00211.20 OEU17413.1 - 2e-46 158.0 0.0 4.3e-46 156.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 OEU17413.1 - 2.2e-32 112.7 2.2 4.8e-32 111.6 2.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PHO4 PF01384.20 OEU17413.1 - 0.088 11.8 0.1 0.53 9.3 0.0 1.9 2 0 0 2 2 2 0 Phosphate transporter family TMEM51 PF15345.6 OEU17413.1 - 0.16 11.8 0.2 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Sigma_reg_N PF13800.6 OEU17413.1 - 0.63 10.4 5.7 8.5 6.7 0.1 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal zf-CCHC PF00098.23 OEU17414.1 - 0.00025 21.0 6.9 0.0008 19.4 0.8 2.8 3 0 0 3 3 3 2 Zinc knuckle Methyltransf_32 PF13679.6 OEU17414.1 - 0.001 19.1 4.5 0.027 14.5 4.5 2.3 1 1 0 1 1 1 1 Methyltransferase domain zf-CCHC_3 PF13917.6 OEU17414.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle MTS PF05175.14 OEU17414.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PDZ PF00595.24 OEU17415.1 - 4.8e-08 33.2 0.2 2.8e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OEU17415.1 - 1.5e-06 28.0 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OEU17415.1 - 0.0025 18.1 0.1 0.092 13.1 0.0 2.3 2 0 0 2 2 2 1 PDZ domain Ank_2 PF12796.7 OEU17416.1 - 8.4e-08 32.7 0.1 0.00015 22.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU17416.1 - 7.7e-06 25.9 0.2 0.00049 20.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OEU17416.1 - 1.6e-05 25.1 0.0 0.044 14.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU17416.1 - 0.00042 20.6 0.1 0.0057 17.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OEU17416.1 - 0.0095 16.5 0.2 0.11 13.1 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Methyltr_RsmB-F PF01189.17 OEU17417.1 - 3.4e-28 98.7 0.2 8.2e-28 97.4 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F zf-LITAF-like PF10601.9 OEU17418.1 - 1e-13 51.3 4.7 1.5e-13 50.8 4.7 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain MatE PF01554.18 OEU17419.1 - 1.2e-27 96.6 24.4 7.8e-18 64.6 6.9 2.8 3 0 0 3 3 3 2 MatE ADP_ribosyl_GH PF03747.14 OEU17420.1 - 3.2e-35 122.3 0.1 7e-35 121.2 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase FAM91_C PF14648.6 OEU17421.1 - 0.0021 17.0 0.2 0.0035 16.3 0.2 1.5 1 1 0 1 1 1 1 FAM91 C-terminus Ribosomal_S28e PF01200.18 OEU17422.1 - 2.4e-31 107.5 0.6 2.6e-31 107.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Chorismate_bind PF00425.18 OEU17423.1 - 1e-77 261.2 0.0 1.4e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OEU17423.1 - 4.4e-41 140.8 0.0 7.4e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OEU17423.1 - 2.3e-13 50.4 0.0 4.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 OEU17423.1 - 7.3e-06 26.2 0.1 0.00039 20.6 0.1 3.1 2 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region Chromate_transp PF02417.15 OEU17424.1 - 3.6e-59 199.4 28.5 3.1e-38 131.4 13.5 2.2 2 0 0 2 2 2 2 Chromate transporter SLC3A2_N PF16028.5 OEU17424.1 - 0.6 9.7 2.0 17 5.0 0.6 2.6 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Cupin_8 PF13621.6 OEU17425.1 - 2.1e-19 70.2 0.0 2.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU17425.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 OEU17425.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin IBR PF01485.21 OEU17426.1 - 3.1e-05 24.1 6.4 3.1e-05 24.1 6.4 5.0 2 1 2 4 4 4 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OEU17426.1 - 5.4e-05 23.1 4.2 5.4e-05 23.1 4.2 3.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU17426.1 - 0.00023 20.9 2.1 0.00023 20.9 2.1 5.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU17426.1 - 0.00064 20.0 5.1 0.00064 20.0 5.1 4.5 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OEU17426.1 - 0.0027 17.6 4.0 0.0027 17.6 4.0 4.6 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU17426.1 - 0.0083 16.0 1.8 0.0083 16.0 1.8 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OEU17426.1 - 0.031 14.4 20.1 0.16 12.1 1.1 3.9 3 1 0 3 3 3 0 Zinc-binding RING-finger Epimerase PF01370.21 OEU17427.1 - 1.2e-24 87.1 0.0 2.2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU17427.1 - 4e-16 59.3 0.0 2.7e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OEU17427.1 - 4.8e-06 25.9 0.0 0.0054 15.9 0.1 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 OEU17427.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OEU17427.1 - 0.11 12.8 0.0 0.53 10.5 0.0 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Big_10 PF17964.1 OEU17429.1 - 0.19 11.7 10.3 0.24 11.3 1.8 2.3 1 1 2 3 3 3 0 Bacterial Ig domain RR_TM4-6 PF06459.12 OEU17429.1 - 2.7 7.7 12.0 3.4 7.4 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4681 PF15732.5 OEU17429.1 - 8.9 6.6 17.1 17 5.7 0.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4681) FHA PF00498.26 OEU17430.1 - 3.7e-18 65.6 0.3 1.5e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 FHA domain ANAPC4_WD40 PF12894.7 OEU17430.1 - 2.6e-05 24.4 0.0 17 5.8 0.0 5.3 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Yop-YscD_cpl PF16697.5 OEU17430.1 - 2.8e-05 24.3 0.0 0.0069 16.7 0.0 2.6 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PilN PF05137.13 OEU17430.1 - 0.0034 17.5 1.0 0.15 12.2 0.1 2.5 2 0 0 2 2 2 1 Fimbrial assembly protein (PilN) WD40 PF00400.32 OEU17430.1 - 0.0035 18.2 12.1 0.27 12.2 0.6 6.0 6 1 0 6 6 6 1 WD domain, G-beta repeat TMEM247 PF15444.6 OEU17430.1 - 0.54 10.3 3.0 1.2 9.1 3.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 Nop16 PF09420.10 OEU17431.1 - 5.9e-18 65.7 7.2 4.6e-10 39.9 0.3 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Mpv17_PMP22 PF04117.12 OEU17432.1 - 8.7e-15 54.7 0.1 2e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Wzz PF02706.15 OEU17432.1 - 0.0018 18.5 0.0 2.8 8.3 0.0 2.6 2 0 0 2 2 2 2 Chain length determinant protein Homoserine_dh PF00742.19 OEU17433.1 - 7.2e-44 149.8 0.1 9.6e-44 149.3 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OEU17433.1 - 6.7e-13 49.3 0.0 1.4e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PduV-EutP PF10662.9 OEU17433.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MAPEG PF01124.18 OEU17434.1 - 5.9e-06 26.2 1.1 5.9e-06 26.2 1.1 1.5 2 0 0 2 2 2 1 MAPEG family Bestrophin PF01062.21 OEU17435.1 - 3e-25 89.2 0.5 5.3e-25 88.4 0.5 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2842 PF11003.8 OEU17435.1 - 0.17 12.2 0.6 0.34 11.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Peptidase_S49_N PF08496.10 OEU17437.1 - 0.00056 20.0 1.3 0.00076 19.6 1.3 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Neurensin PF14927.6 OEU17437.1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Neurensin DUF3185 PF11381.8 OEU17437.1 - 0.044 13.8 0.3 0.075 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) SLATT_6 PF18169.1 OEU17437.1 - 0.046 13.3 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 PPL5 PF18168.1 OEU17437.1 - 0.14 11.4 2.7 0.17 11.1 2.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NARP1 PF12569.8 OEU17437.1 - 0.2 10.5 5.4 0.24 10.2 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FemAB PF02388.16 OEU17437.1 - 0.24 10.2 3.3 0.32 9.8 3.3 1.1 1 0 0 1 1 1 0 FemAB family RNA_pol_Rpc4 PF05132.14 OEU17437.1 - 0.24 11.8 2.7 0.28 11.6 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF755 PF05501.11 OEU17437.1 - 0.36 11.1 26.8 0.53 10.6 26.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 OEU17437.1 - 0.43 10.8 14.7 0.65 10.2 14.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Baculo_PP31 PF05311.11 OEU17437.1 - 1.6 8.2 10.7 2.2 7.7 10.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DDRGK PF09756.9 OEU17437.1 - 2.4 7.7 13.3 3.2 7.3 13.3 1.1 1 0 0 1 1 1 0 DDRGK domain Ctr PF04145.15 OEU17437.1 - 2.7 8.6 7.8 5.3 7.6 7.8 1.5 1 1 0 1 1 1 0 Ctr copper transporter family Med19 PF10278.9 OEU17437.1 - 3.6 7.5 13.4 4.9 7.1 13.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 OEU17437.1 - 4 6.1 7.8 5.9 5.5 7.8 1.2 1 0 0 1 1 1 0 Presenilin TMEM214 PF10151.9 OEU17437.1 - 9 4.6 6.9 11 4.4 6.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator ATP11 PF06644.11 OEU17437.1 - 9.6 5.9 9.5 12 5.5 9.5 1.1 1 0 0 1 1 1 0 ATP11 protein CRAL_TRIO PF00650.20 OEU17438.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain Ntox50 PF15542.6 OEU17438.1 - 3 8.7 6.0 1 10.2 1.8 2.3 1 1 1 2 2 2 0 Bacterial toxin 50 PI3K_1B_p101 PF10486.9 OEU17439.1 - 0.12 10.1 5.0 0.13 10.0 5.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 OEU17439.1 - 0.31 10.3 2.5 0.42 9.9 2.5 1.1 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 OEU17439.1 - 8.9 6.6 8.1 4.6 7.5 5.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DTC PF18102.1 OEU17440.1 - 2e-40 138.0 0.7 6.4e-40 136.4 0.2 2.0 2 0 0 2 2 2 1 Deltex C-terminal domain zf-RING_2 PF13639.6 OEU17440.1 - 1.5e-08 34.8 9.3 4.3e-08 33.3 9.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU17440.1 - 3e-05 23.8 12.5 5.3e-05 23.0 10.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU17440.1 - 8.7e-05 22.7 9.0 0.00025 21.3 9.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OEU17440.1 - 0.0004 20.3 11.5 0.0013 18.7 11.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU17440.1 - 0.0059 16.6 4.2 0.0059 16.6 4.2 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 OEU17440.1 - 0.0082 15.9 4.7 0.0082 15.9 4.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OEU17440.1 - 0.012 15.4 10.5 0.03 14.2 10.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU17440.1 - 0.016 15.1 11.0 0.051 13.5 11.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU17440.1 - 0.022 14.8 4.9 0.06 13.4 4.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OEU17440.1 - 0.14 12.0 6.4 0.26 11.1 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OEU17440.1 - 1.2 9.1 11.9 7.1 6.6 11.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 CBS PF00571.28 OEU17441.1 - 3.2e-21 75.5 1.3 1.3e-12 48.0 0.3 2.5 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 OEU17443.1 - 2.5e-45 154.9 0.0 2.8e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17443.1 - 6.7e-14 51.8 0.0 8.2e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU17443.1 - 0.0033 16.8 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OEU17443.1 - 0.02 13.7 0.0 0.051 12.3 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OEU17443.1 - 0.05 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MTABC_N PF16185.5 OEU17444.1 - 0.06 12.8 0.5 0.14 11.6 0.5 1.5 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region BSMAP PF12280.8 OEU17444.1 - 8.8 6.5 13.8 5.1 7.3 4.2 3.0 3 1 0 3 3 3 0 Brain specific membrane anchored protein DUF4834 PF16118.5 OEU17445.1 - 0.049 14.6 1.0 12 7.0 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) vATP-synt_E PF01991.18 OEU17446.1 - 2.5e-45 154.3 3.0 3e-45 154.1 3.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Aldedh PF00171.22 OEU17447.1 - 9.3e-138 459.6 0.0 1.1e-137 459.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SOG2 PF10428.9 OEU17449.1 - 8.2 5.5 23.0 0.039 13.1 6.8 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein TRAPP PF04051.16 OEU17450.1 - 6.1e-36 123.3 0.0 7.9e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component AAA_33 PF13671.6 OEU17451.1 - 0.0037 17.4 7.6 0.012 15.8 0.1 3.2 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OEU17451.1 - 0.017 15.5 0.1 0.068 13.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Nha1_C PF08619.10 OEU17451.1 - 0.03 13.6 16.9 0.047 12.9 16.9 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Methyltrn_RNA_2 PF04013.12 OEU17451.1 - 0.047 13.4 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Putative SAM-dependent RNA methyltransferase AAA_18 PF13238.6 OEU17451.1 - 0.065 13.8 0.1 0.065 13.8 0.1 2.6 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OEU17451.1 - 0.22 11.7 2.8 0.3 11.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain DUF3671 PF12420.8 OEU17452.1 - 0.06 13.4 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function Bac_rhamnosid6H PF17389.2 OEU17453.1 - 8.4e-80 268.6 0.2 1.1e-79 268.2 0.2 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OEU17453.1 - 3.1e-37 128.1 0.3 2.2e-35 122.0 0.3 2.5 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 OEU17453.1 - 5.2e-26 90.6 0.0 1.1e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OEU17453.1 - 0.0002 21.1 0.0 0.0007 19.3 0.0 2.0 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Rtf2 PF04641.12 OEU17454.1 - 1.5e-18 67.1 10.6 6.8e-18 65.0 10.6 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger DUF4604 PF15377.6 OEU17454.1 - 0.58 10.6 19.4 0.35 11.3 17.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Strep_SA_rep PF06696.11 OEU17455.1 - 0.075 13.1 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Methyltransf_16 PF10294.9 OEU17456.1 - 2.3e-11 43.7 0.2 4.1e-09 36.4 0.2 2.2 1 1 0 1 1 1 1 Lysine methyltransferase AlaDh_PNT_C PF01262.21 OEU17456.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2405 PF10293.9 OEU17457.1 - 0.0069 16.3 1.0 0.016 15.2 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Adeno_PV PF03910.13 OEU17457.1 - 0.033 12.9 0.5 0.059 12.1 0.5 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF5607 PF18355.1 OEU17457.1 - 0.075 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) GTP1_OBG PF01018.22 OEU17458.1 - 1.3e-38 132.0 3.5 2e-38 131.4 3.5 1.3 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 OEU17458.1 - 1.6e-23 83.0 0.0 3.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU17458.1 - 1e-10 41.3 0.1 5.2e-10 39.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 OEU17458.1 - 0.0015 17.5 0.2 0.36 9.8 0.1 2.5 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 OEU17458.1 - 0.0037 17.2 1.0 0.073 13.0 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 OEU17458.1 - 0.006 16.3 0.1 0.028 14.2 0.1 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 OEU17458.1 - 0.0094 15.4 0.0 0.078 12.4 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OEU17458.1 - 0.011 15.3 0.0 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 OEU17458.1 - 0.026 14.1 0.0 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 Ras family MMR_HSR1_Xtn PF16897.5 OEU17458.1 - 0.045 13.8 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 OEU17458.1 - 0.12 12.5 0.0 4.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Dynamin family Nas2_N PF18265.1 OEU17460.1 - 2.3e-16 59.4 0.6 4.9e-16 58.4 0.1 1.8 1 1 1 2 2 2 1 Nas2 N_terminal domain PDZ_2 PF13180.6 OEU17460.1 - 0.01 16.1 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 OEU17460.1 - 0.076 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zf-RING_2 PF13639.6 OEU17461.1 - 2.1e-05 24.8 7.8 4.2e-05 23.8 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OEU17461.1 - 0.0015 18.5 1.9 0.0023 17.9 1.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 OEU17461.1 - 0.0017 18.1 7.0 0.0072 16.1 7.0 2.1 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OEU17461.1 - 0.037 13.8 3.5 0.086 12.6 3.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger PDZ_6 PF17820.1 OEU17461.1 - 0.067 13.0 0.3 0.24 11.3 0.1 2.0 2 0 0 2 2 2 0 PDZ domain zf-C3HC4 PF00097.25 OEU17461.1 - 0.082 12.8 9.0 0.21 11.5 9.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OEU17461.1 - 0.16 12.1 2.9 0.19 11.9 1.5 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 OEU17461.1 - 0.27 11.1 10.5 3.6 7.5 10.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 OEU17461.1 - 1.3 9.2 5.6 3.1 8.0 5.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 OEU17461.1 - 1.8 8.5 6.2 6.6 6.7 6.2 1.9 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 OEU17461.1 - 2.8 8.0 9.1 8.9 6.4 9.2 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Pro_isomerase PF00160.21 OEU17462.1 - 7.9e-14 52.2 0.0 2.3e-13 50.7 0.0 1.7 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EamA PF00892.20 OEU17463.1 - 1.2e-14 54.6 19.1 6.9e-09 36.0 8.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU17463.1 - 0.11 11.9 3.7 0.053 12.9 0.5 1.9 2 0 0 2 2 2 0 Triose-phosphate Transporter family CorA PF01544.18 OEU17464.1 - 5.9e-05 22.5 1.0 8.6e-05 22.0 0.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ost5 PF05251.12 OEU17464.1 - 0.53 10.6 5.6 9.1 6.6 7.6 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 GSHPx PF00255.19 OEU17465.1 - 1.7e-11 43.6 0.0 4e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione peroxidase PseudoU_synth_2 PF00849.22 OEU17466.1 - 1.7e-16 60.7 0.1 6.2e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 OEU17466.1 - 0.00021 20.9 0.7 0.00043 19.9 0.7 1.6 1 0 0 1 1 1 1 S4 domain SR-25 PF10500.9 OEU17466.1 - 0.039 13.6 13.2 0.071 12.7 13.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Menin PF05053.13 OEU17466.1 - 0.097 11.0 2.1 0.13 10.6 2.1 1.1 1 0 0 1 1 1 0 Menin Ocular_alb PF02101.15 OEU17466.1 - 0.13 11.1 1.4 0.22 10.4 1.4 1.3 1 0 0 1 1 1 0 Ocular albinism type 1 protein JUPITER PF17054.5 OEU17466.1 - 0.17 11.4 5.4 0.23 10.9 5.4 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter LptF_LptG PF03739.14 OEU17466.1 - 0.23 10.3 0.1 0.37 9.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG CD52 PF15116.6 OEU17466.1 - 0.5 10.4 3.8 17 5.6 5.1 2.7 2 0 0 2 2 2 0 CAMPATH-1 antigen DUF755 PF05501.11 OEU17466.1 - 9.6 6.5 23.4 0.55 10.5 17.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF1604 PF07713.13 OEU17468.1 - 5.8e-20 70.9 1.8 5.8e-20 70.9 1.8 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) GlcNAc PF11397.8 OEU17469.1 - 7.1e-44 150.7 0.2 3e-32 112.4 0.0 3.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Form_Nir_trans PF01226.17 OEU17470.1 - 5.3e-65 219.1 25.4 6.1e-65 218.9 25.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter CBM_1 PF00734.18 OEU17470.1 - 0.074 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungal cellulose binding domain PHD PF00628.29 OEU17471.1 - 9.1e-10 38.3 10.0 1.4e-09 37.7 10.0 1.3 1 1 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 OEU17471.1 - 0.00043 20.3 10.3 0.0041 17.2 10.3 1.9 1 1 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 OEU17471.1 - 0.00048 20.2 2.7 0.00062 19.8 2.7 1.2 1 0 0 1 1 1 1 KIAA1045 RING finger zf-HC5HC2H PF13771.6 OEU17471.1 - 0.00082 19.6 2.1 0.00091 19.4 2.1 1.0 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-PHD-like PF15446.6 OEU17471.1 - 0.0011 18.6 2.7 0.0011 18.6 2.7 1.4 1 1 1 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OEU17471.1 - 1 9.3 8.9 0.16 11.8 4.3 2.0 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OEU17471.1 - 8.8 6.3 17.6 0.64 10.0 10.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ank_4 PF13637.6 OEU17472.1 - 6.5e-06 26.6 0.6 0.0012 19.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU17472.1 - 1e-05 26.0 0.0 1.8e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU17472.1 - 0.00011 22.3 0.0 0.097 13.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OEU17472.1 - 0.00014 22.1 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SoPB_HTH PF18090.1 OEU17472.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Centromere-binding protein HTH domain CHORD PF04968.12 OEU17473.1 - 8.3e-18 64.9 9.7 1.7e-17 63.9 9.7 1.5 1 0 0 1 1 1 1 CHORD BUD22 PF09073.10 OEU17474.1 - 0.37 10.1 6.2 0.68 9.2 6.2 1.4 1 0 0 1 1 1 0 BUD22 PCI PF01399.27 OEU17475.1 - 0.0022 18.5 0.0 0.0041 17.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain SPX PF03105.19 OEU17475.1 - 0.026 14.5 5.5 0.059 13.3 5.5 1.5 1 0 0 1 1 1 0 SPX domain Folliculin_C PF16692.5 OEU17475.1 - 0.049 13.4 0.4 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Folliculin C-terminal domain Arm PF00514.23 OEU17475.1 - 0.054 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat NADH_4Fe-4S PF10589.9 OEU17476.1 - 0.015 15.3 1.4 0.03 14.4 1.4 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Nup54 PF13874.6 OEU17477.1 - 0.0016 18.5 0.5 0.0021 18.2 0.5 1.2 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DUF2730 PF10805.8 OEU17477.1 - 0.047 13.8 1.8 1.3 9.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF3287 PF11690.8 OEU17477.1 - 0.091 12.5 0.6 0.14 11.9 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Glyco_hydro_99 PF16317.5 OEU17478.1 - 2.3e-17 63.2 4.4 9.7e-09 34.8 0.0 2.6 2 1 0 3 3 3 2 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 OEU17478.1 - 2e-08 34.1 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase WbsX Pox_A32 PF04665.12 OEU17478.1 - 0.038 13.5 0.1 0.11 12.0 0.1 1.6 1 1 1 2 2 2 0 Poxvirus A32 protein Bac_rhamnosid6H PF17389.2 OEU17479.1 - 9.1e-46 156.7 2.4 5.2e-32 111.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OEU17479.1 - 2e-18 66.8 0.0 5.7e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 OEU17479.1 - 0.12 12.1 0.0 0.38 10.6 0.0 1.9 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain 2OG-FeII_Oxy PF03171.20 OEU17480.1 - 1.7e-12 47.7 0.3 2.2e-11 44.1 0.3 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OEU17480.1 - 2.2e-11 44.5 1.0 5.2e-11 43.3 0.3 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Cwf_Cwc_15 PF04889.12 OEU17481.1 - 2.8e-43 148.5 12.6 9e-28 97.7 8.4 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Herpes_US12 PF05363.12 OEU17481.1 - 0.094 13.4 1.1 0.15 12.8 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus US12 family Pro-rich PF15240.6 OEU17482.1 - 0.043 14.1 4.7 0.14 12.5 4.7 1.7 1 1 0 1 1 1 0 Proline-rich ABC1 PF03109.16 OEU17483.1 - 1.9e-25 89.4 0.1 3.7e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 OEU17483.1 - 5.1e-09 35.9 0.0 1.5e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 OEU17483.1 - 7.5e-05 22.8 0.3 0.00046 20.2 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Na_Ca_ex PF01699.24 OEU17484.1 - 1.1e-42 145.5 23.8 3.1e-23 82.4 12.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Insulin_TMD PF17870.1 OEU17484.1 - 0.15 12.1 1.5 0.57 10.3 0.7 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF347 PF03988.12 OEU17484.1 - 0.35 11.1 7.0 8.5 6.7 0.1 3.9 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) DUF445 PF04286.12 OEU17485.1 - 0.03 14.1 7.9 0.023 14.5 4.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF445) CSF-1 PF05337.11 OEU17485.1 - 0.11 12.6 0.6 0.29 11.2 0.6 1.8 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) GerD PF17898.1 OEU17485.1 - 0.14 12.1 4.2 0.08 12.9 0.6 2.5 2 1 0 2 2 2 0 Spore germination GerD central core domain DUF3149 PF11346.8 OEU17485.1 - 0.21 11.2 2.6 8.9 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Glypican PF01153.19 OEU17485.1 - 0.23 10.3 1.7 0.39 9.5 1.7 1.3 1 0 0 1 1 1 0 Glypican MA3 PF02847.17 OEU17485.1 - 0.4 10.7 2.1 0.73 9.8 0.1 2.5 3 0 0 3 3 3 0 MA3 domain MGC-24 PF05283.11 OEU17485.1 - 1.4 9.3 7.0 0.056 13.9 0.8 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ALG11_N PF15924.5 OEU17486.1 - 2.2e-42 145.5 8.5 1.3e-31 110.3 5.4 2.3 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OEU17486.1 - 1.6e-25 89.6 0.0 1.5e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU17486.1 - 2.9e-10 40.7 0.0 2.6e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Nrap_D2 PF17403.2 OEU17486.1 - 0.043 13.6 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain SATase_N PF06426.14 OEU17487.1 - 8.8e-36 122.5 0.3 1.5e-35 121.7 0.1 1.5 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 OEU17487.1 - 5.3e-11 41.8 11.1 2.7e-07 30.1 3.0 3.3 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OEU17487.1 - 2.3e-05 24.0 11.5 0.0013 18.5 6.2 3.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Heme_oxygenase PF01126.20 OEU17488.1 - 0.0072 16.1 0.0 0.039 13.7 0.0 1.9 1 1 0 1 1 1 1 Heme oxygenase ABC1 PF03109.16 OEU17489.1 - 2.4e-30 105.1 0.0 5.1e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU17489.1 - 0.00087 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU17489.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain TrmO PF01980.16 OEU17490.1 - 6.7e-40 136.0 0.0 7.6e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 tRNA-methyltransferase O Pkinase PF00069.25 OEU17491.1 - 6.7e-37 127.3 0.1 1.7e-28 99.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17491.1 - 1.9e-14 53.6 0.1 5.9e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU17491.1 - 4.3e-05 22.5 0.1 7.9e-05 21.6 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OEU17491.1 - 0.00058 19.3 0.2 0.48 9.7 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 OEU17491.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU17491.1 - 0.082 12.8 0.2 0.5 10.3 0.1 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ammonium_transp PF00909.21 OEU17492.1 - 4.1e-107 358.3 20.7 5.1e-107 358.0 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Mannosyl_trans2 PF04188.13 OEU17493.1 - 4e-35 122.0 25.8 1.3e-34 120.3 12.8 3.7 2 1 1 3 3 3 2 Mannosyltransferase (PIG-V) SUIM_assoc PF16619.5 OEU17493.1 - 0.046 13.8 1.4 0.14 12.2 0.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2681 PF10883.8 OEU17493.1 - 0.075 13.4 0.7 0.31 11.5 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Gar1 PF04410.14 OEU17494.1 - 2.2e-12 47.0 17.5 1.1e-07 31.7 2.1 3.7 2 1 0 2 2 2 2 Gar1/Naf1 RNA binding region SMN PF06003.12 OEU17494.1 - 5.1 6.3 28.2 0.32 10.2 6.8 2.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) 4_1_CTD PF05902.13 OEU17495.1 - 0.038 14.1 0.7 0.1 12.7 0.7 1.7 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Beach PF02138.18 OEU17496.1 - 1e-119 399.0 0.5 1.2e-119 398.8 0.5 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OEU17496.1 - 4.8e-06 26.6 0.3 4.8e-06 26.6 0.3 1.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Ribosomal_L2_C PF03947.18 OEU17497.1 - 2.5e-42 144.0 2.5 5.4e-42 143.0 2.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OEU17497.1 - 3.7e-18 65.2 0.0 9.2e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DNA_primase_lrg PF04104.14 OEU17498.1 - 6.9e-68 228.9 0.6 1.5e-67 227.8 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Thiolase_N PF00108.23 OEU17499.1 - 2.2e-72 243.6 1.6 3.5e-72 242.9 1.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OEU17499.1 - 2.3e-38 130.6 0.0 9.6e-38 128.6 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OEU17499.1 - 5.2e-06 26.2 1.7 1.6e-05 24.6 0.6 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 OEU17499.1 - 9.4e-06 24.5 0.2 1.9e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 OEU17499.1 - 0.013 15.4 1.2 0.54 10.1 0.6 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_3 PF01494.19 OEU17500.1 - 6.8e-08 32.1 0.0 8.7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF1117 PF06547.12 OEU17500.1 - 0.018 15.6 0.0 0.033 14.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1117) Ion_trans PF00520.31 OEU17501.1 - 1.2e-21 77.1 54.1 5.8e-12 45.4 21.7 2.3 2 0 0 2 2 2 2 Ion transport protein Ribosomal_S27e PF01667.17 OEU17502.1 - 1.8e-26 91.6 4.8 2.2e-26 91.3 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 OEU17502.1 - 0.022 15.2 1.1 0.057 13.8 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Mu-like_Com PF10122.9 OEU17502.1 - 0.044 13.2 2.0 2.3 7.7 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Retrotran_gag_2 PF14223.6 OEU17504.1 - 0.0037 16.9 5.5 0.038 13.7 0.0 2.7 2 1 1 3 3 3 1 gag-polypeptide of LTR copia-type MnmE_helical PF12631.7 OEU17504.1 - 0.0069 16.6 1.7 0.01 16.0 1.7 1.2 1 0 0 1 1 1 1 MnmE helical domain DRAT PF07357.11 OEU17504.1 - 0.053 12.7 0.5 0.085 12.0 0.5 1.5 1 1 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF1860 PF08949.10 OEU17504.1 - 0.076 12.7 0.3 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) BLOC1_2 PF10046.9 OEU17504.1 - 0.13 12.6 9.0 0.12 12.6 2.6 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1104 PF06518.11 OEU17504.1 - 0.18 12.2 7.5 2.8 8.4 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) Sec8_exocyst PF04048.14 OEU17504.1 - 0.33 10.9 6.2 1.7 8.5 5.9 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain eIF3_N PF09440.10 OEU17504.1 - 0.93 9.9 9.7 5.8 7.4 3.4 2.4 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain Med9 PF07544.13 OEU17504.1 - 2.2 8.5 6.3 21 5.3 1.8 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MscS_porin PF12795.7 OEU17504.1 - 3.7 7.0 13.8 0.35 10.4 7.2 2.3 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4399 PF14347.6 OEU17505.1 - 1.1e-24 86.6 2.4 1.4e-24 86.3 1.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4399) FAM176 PF14851.6 OEU17506.1 - 0.17 11.6 2.4 0.27 10.9 0.3 2.3 3 0 0 3 3 3 0 FAM176 family Mucin PF01456.17 OEU17506.1 - 0.71 9.9 19.1 1.2 9.1 0.8 4.0 4 0 0 4 4 4 0 Mucin-like glycoprotein DUF3385 PF11865.8 OEU17506.1 - 4.1 7.3 4.7 13 5.6 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) MITF_TFEB_C_3_N PF15951.5 OEU17506.1 - 5.4 7.6 9.8 0.44 11.2 2.9 2.4 3 0 0 3 3 3 0 MITF/TFEB/TFEC/TFE3 N-terminus Ion_trans PF00520.31 OEU17507.1 - 7e-18 64.8 37.2 3e-09 36.5 18.1 2.4 2 0 0 2 2 2 2 Ion transport protein Lactamase_B PF00753.27 OEU17508.1 - 2.3e-17 63.7 2.2 3.5e-14 53.3 0.5 2.3 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OEU17508.1 - 5.3e-07 29.4 0.1 6.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SIR2 PF02146.17 OEU17509.1 - 8.5e-33 113.7 0.1 9e-32 110.4 0.1 2.1 1 1 0 1 1 1 1 Sir2 family Ribosomal_L24e PF01246.20 OEU17510.1 - 3.8e-32 110.3 7.7 3.8e-32 110.3 7.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CFAP91 PF14738.6 OEU17510.1 - 0.025 14.6 3.4 0.05 13.7 3.4 1.5 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 IML1 PF12257.8 OEU17511.1 - 1.4e-85 286.9 0.0 1.7e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DUF4154 PF13689.6 OEU17511.1 - 0.097 12.9 0.1 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 YfiR/HmsC-like GH-E PF14410.6 OEU17512.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues zf-C3HC4_3 PF13920.6 OEU17513.1 - 0.077 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PTP_N PF12453.8 OEU17514.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Dicty_REP PF05086.12 OEU17514.1 - 0.032 12.2 0.1 0.032 12.2 0.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 OEU17515.1 - 4.6 7.2 21.8 0.095 12.7 14.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein CENP-B_dimeris PF09026.10 OEU17515.1 - 5.8 7.4 8.0 9.9 6.6 0.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PseudoU_synth_1 PF01416.20 OEU17516.1 - 9.6e-19 67.8 0.0 1.9e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase RalF_SCD PF18248.1 OEU17516.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain SAS4 PF15460.6 OEU17516.1 - 0.3 11.2 2.7 28 4.9 0.1 3.2 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 Peptidase_S41 PF03572.18 OEU17517.1 - 2.9e-39 134.3 0.9 4.5e-39 133.7 0.9 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 OEU17517.1 - 6.9e-09 35.9 0.2 2.6e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OEU17517.1 - 2.4e-06 27.3 0.0 6.1e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 OEU17517.1 - 0.00065 19.7 1.0 0.0015 18.6 1.0 1.6 1 1 0 1 1 1 1 Tricorn protease C1 domain PDZ PF00595.24 OEU17517.1 - 0.0037 17.6 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PALP PF00291.25 OEU17518.1 - 1.8e-56 191.8 0.2 2.2e-56 191.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1749 PF08538.10 OEU17519.1 - 1.3e-23 83.6 0.0 1.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) MMPL PF03176.15 OEU17520.1 - 0.28 10.1 4.1 0.36 9.7 4.1 1.1 1 0 0 1 1 1 0 MMPL family Pyr_redox_2 PF07992.14 OEU17521.1 - 4.8e-33 114.7 0.0 5.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU17521.1 - 4.6e-05 23.9 0.1 0.00014 22.3 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU17521.1 - 0.0011 18.2 0.4 0.0049 16.2 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OEU17521.1 - 0.096 11.7 1.5 2.7 6.9 0.1 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 OEU17521.1 - 0.11 11.2 3.6 2.7 6.6 0.0 2.2 1 1 1 2 2 2 0 HI0933-like protein Cupin_8 PF13621.6 OEU17523.1 - 1.5e-39 136.2 0.0 2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU17523.1 - 1.5e-10 41.0 0.0 9.4e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 OEU17523.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 OEU17523.1 - 0.013 15.9 0.1 0.068 13.6 0.0 2.2 2 1 0 2 2 2 0 JmjC domain, hydroxylase Trigger_N PF05697.13 OEU17524.1 - 1e-19 71.2 0.0 1e-19 71.2 0.0 4.2 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 OEU17524.1 - 6.3e-11 42.6 14.4 6.3e-11 42.6 14.4 2.6 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 OEU17524.1 - 2.7e-06 27.6 0.1 7.3e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N_2 PF13623.6 OEU17524.1 - 1.1 9.1 7.1 0.73 9.7 3.4 2.4 1 1 1 2 2 2 0 SurA N-terminal domain DHH PF01368.20 OEU17526.1 - 3.4e-13 49.7 0.1 6.7e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 OEU17526.1 - 2.3e-09 37.6 0.0 3.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain RRM_Rrp7 PF17799.1 OEU17527.1 - 0.028 14.2 0.1 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Cwf_Cwc_15 PF04889.12 OEU17527.1 - 2 8.1 9.4 2.7 7.7 5.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ANTH PF07651.16 OEU17528.1 - 0.3 10.0 12.7 0.42 9.6 0.4 2.9 2 1 1 3 3 3 0 ANTH domain PDEase_I PF00233.19 OEU17529.1 - 1.2e-23 84.1 0.2 3e-22 79.5 0.2 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Methyltransf_16 PF10294.9 OEU17530.1 - 3.4e-06 26.9 0.1 0.00076 19.3 0.0 3.1 3 0 0 3 3 3 2 Lysine methyltransferase Mucin PF01456.17 OEU17530.1 - 0.0077 16.2 6.9 0.0077 16.2 6.9 2.2 3 0 0 3 3 3 1 Mucin-like glycoprotein Abhydrolase_3 PF07859.13 OEU17532.1 - 8.6e-12 45.4 0.1 1.2e-11 44.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OEU17532.1 - 2.7e-11 43.1 0.1 1.9e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 OEU17532.1 - 1.5e-06 27.9 0.2 0.0056 16.2 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OEU17532.1 - 7.6e-06 26.7 0.0 1.3e-05 25.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU17532.1 - 8e-06 25.7 0.7 0.025 14.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU17532.1 - 1.6e-05 24.3 0.0 0.00011 21.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OEU17532.1 - 2.6e-05 24.1 0.0 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 OEU17532.1 - 0.0064 16.2 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 OEU17532.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 OEU17532.1 - 0.064 12.9 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative esterase LIP PF03583.14 OEU17532.1 - 0.091 12.1 0.1 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase GST_C_3 PF14497.6 OEU17533.1 - 3.9e-06 27.0 0.1 7.2e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.6 OEU17534.1 - 4.2e-07 29.9 0.0 9.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU17534.1 - 7.1e-06 26.6 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU17534.1 - 0.0017 18.9 0.0 0.0036 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OEU17534.1 - 0.0029 17.1 0.0 0.014 14.9 0.0 2.1 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 OEU17534.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OEU17534.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 OEU17534.1 - 0.041 14.6 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OEU17535.1 - 3.8e-35 121.4 0.0 1e-34 120.0 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 OEU17535.1 - 4.1e-17 62.7 0.6 9.9e-17 61.4 0.6 1.7 1 0 0 1 1 1 1 NusB family Cons_hypoth95 PF03602.15 OEU17535.1 - 0.0019 17.9 0.0 0.0097 15.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 OEU17535.1 - 0.013 15.1 0.1 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF3877 PF12993.7 OEU17535.1 - 0.087 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Copine PF07002.16 OEU17538.1 - 5.1e-28 98.0 0.0 9.3e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.30 OEU17538.1 - 2.6e-16 59.8 0.0 2e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain ABC_membrane PF00664.23 OEU17539.1 - 2.9e-43 148.5 6.2 4.2e-43 148.0 6.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OEU17539.1 - 9.8e-33 113.6 0.0 1.9e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU17539.1 - 8.8e-08 31.8 0.0 2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OEU17539.1 - 0.00023 21.0 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 OEU17539.1 - 0.00054 19.9 0.0 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 OEU17539.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 OEU17539.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OEU17539.1 - 0.0027 18.1 0.1 0.0087 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OEU17539.1 - 0.0044 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU17539.1 - 0.0078 16.5 0.1 0.055 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OEU17539.1 - 0.014 15.9 0.1 0.22 12.0 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU17539.1 - 0.028 14.0 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OEU17539.1 - 0.06 13.9 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OEU17539.1 - 0.096 12.5 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OEU17539.1 - 0.13 11.0 0.0 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 OEU17539.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit EMP24_GP25L PF01105.24 OEU17541.1 - 0.00074 19.5 1.4 0.00074 19.5 1.4 2.1 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD ABC2_membrane_3 PF12698.7 OEU17541.1 - 0.077 12.1 0.5 0.08 12.0 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GSHPx PF00255.19 OEU17543.1 - 1.5e-08 34.1 0.1 2.6e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase DAO PF01266.24 OEU17544.1 - 3.3e-22 79.5 1.2 1e-17 64.7 1.8 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU17544.1 - 3.7e-08 33.0 3.3 1.5e-06 27.7 3.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU17544.1 - 8.6e-08 32.3 0.4 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OEU17544.1 - 5.6e-05 22.4 8.4 0.0019 17.3 8.4 2.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OEU17544.1 - 6.2e-05 22.2 2.0 0.0045 16.1 0.8 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 OEU17544.1 - 7.8e-05 21.9 1.6 0.018 14.1 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OEU17544.1 - 0.0001 21.7 0.5 0.28 10.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OEU17544.1 - 0.0002 21.5 0.2 0.00042 20.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OEU17544.1 - 0.00032 19.9 0.2 0.0078 15.4 0.1 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OEU17544.1 - 0.0031 16.8 0.1 0.0055 16.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OEU17544.1 - 0.0078 15.0 2.0 1.2 7.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 OEU17544.1 - 0.008 15.5 0.9 0.53 9.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OEU17544.1 - 0.019 13.6 0.9 0.23 10.0 0.1 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GMC_oxred_N PF00732.19 OEU17544.1 - 0.032 13.6 0.7 1.1 8.5 0.1 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.27 OEU17544.1 - 0.052 14.1 0.8 6.2 7.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU17544.1 - 1.3 8.3 10.6 2.9 7.2 0.1 2.8 1 1 2 3 3 3 0 FAD dependent oxidoreductase RRM_1 PF00076.22 OEU17545.1 - 1.4e-21 76.1 0.1 1.4e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU17545.1 - 0.0001 21.9 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OEU17545.1 - 0.18 12.0 0.8 9.6 6.4 0.0 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Mucin PF01456.17 OEU17545.1 - 5.3 7.0 21.6 8.3 6.4 21.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Proteasome PF00227.26 OEU17546.1 - 2.2e-57 193.6 0.0 3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU17546.1 - 7.3e-14 51.1 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ipi1_N PF12333.8 OEU17547.1 - 0.03 14.9 0.2 0.03 14.9 0.2 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF842 PF05811.13 OEU17548.1 - 3.9e-32 110.7 9.4 4.6e-32 110.5 9.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Col_cuticle_N PF01484.17 OEU17548.1 - 0.0025 17.8 0.3 0.0046 17.0 0.3 1.4 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain T3SS_needle_F PF09392.10 OEU17548.1 - 0.0047 17.1 1.3 0.0047 17.1 1.3 2.2 2 0 0 2 2 2 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF1326 PF07040.11 OEU17548.1 - 0.019 15.0 0.2 0.069 13.2 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1326) KxDL PF10241.9 OEU17548.1 - 0.032 14.5 3.2 2 8.8 0.3 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 OEU17548.1 - 0.11 12.0 2.8 0.12 11.9 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1S3 PF15753.5 OEU17548.1 - 0.12 12.4 1.9 0.15 12.2 1.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF1690 PF07956.11 OEU17548.1 - 0.16 12.4 5.0 0.21 12.0 1.0 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) TipAS PF07739.13 OEU17548.1 - 0.19 12.3 1.6 0.34 11.5 0.3 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF1525 PF07511.11 OEU17548.1 - 0.2 11.8 2.7 0.12 12.5 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) ApoLp-III PF07464.11 OEU17548.1 - 0.2 11.7 4.3 0.5 10.5 3.0 2.3 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) zf-Tim10_DDP PF02953.15 OEU17548.1 - 0.43 10.3 10.4 0.48 10.1 1.6 2.7 1 1 1 2 2 2 0 Tim10/DDP family zinc finger Apolipoprotein PF01442.18 OEU17548.1 - 0.59 10.0 4.7 4.6 7.1 4.1 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain WXG100 PF06013.12 OEU17548.1 - 0.67 10.2 7.8 2.7 8.3 0.2 2.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG OmpH PF03938.14 OEU17548.1 - 0.87 9.9 8.5 5.2 7.4 8.5 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF148 PF02520.17 OEU17548.1 - 2.1 8.5 6.3 2 8.5 2.1 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF148 Adaptin_N PF01602.20 OEU17549.1 - 4.5e-114 381.9 0.4 5.4e-114 381.6 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OEU17549.1 - 5.1e-08 33.1 4.0 0.00037 20.6 0.5 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OEU17549.1 - 0.0076 15.8 0.1 1.3 8.6 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal Nipped-B_C PF12830.7 OEU17549.1 - 0.039 13.9 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Vac14_Fab1_bd PF12755.7 OEU17549.1 - 0.096 13.3 0.2 2.9 8.6 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OEU17549.1 - 0.5 10.8 1.9 6.8 7.2 0.0 3.8 5 0 0 5 5 5 0 HEAT repeat vATP-synt_AC39 PF01992.16 OEU17550.1 - 1.8e-108 363.0 0.1 2e-108 362.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit G-alpha PF00503.20 OEU17551.1 - 2.8e-81 273.4 10.2 5.5e-65 219.8 5.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 OEU17551.1 - 2.5e-15 56.4 2.3 3.9e-12 46.0 0.5 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OEU17551.1 - 1.8e-05 25.0 0.5 0.042 14.1 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OEU17551.1 - 0.00045 19.6 4.1 0.014 14.8 4.1 2.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU17551.1 - 0.004 17.2 0.5 0.33 11.1 0.5 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU17551.1 - 0.0053 16.3 0.2 0.092 12.3 0.0 2.3 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 OEU17551.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM43 PF07787.12 OEU17552.1 - 1.9e-19 70.1 0.9 2.8e-17 62.9 0.0 2.7 3 0 0 3 3 3 2 Transmembrane protein 43 E1-E2_ATPase PF00122.20 OEU17552.1 - 0.75 9.3 6.4 2.9 7.4 5.3 2.1 2 0 0 2 2 2 0 E1-E2 ATPase DUF1673 PF07895.11 OEU17552.1 - 1.7 8.3 4.2 1.8 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) DUF2207 PF09972.9 OEU17552.1 - 2.4 6.8 5.2 15 4.2 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sec1 PF00995.23 OEU17553.1 - 2.6e-116 390.1 0.0 3e-116 390.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ribosomal_S14 PF00253.21 OEU17554.1 - 3.2e-12 46.0 0.6 3.9e-12 45.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e M16C_assoc PF08367.11 OEU17556.1 - 3.2e-44 151.0 0.0 6.3e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OEU17556.1 - 2.7e-06 27.5 0.1 8.9e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 Peptidase M16 inactive domain FSH1 PF03959.13 OEU17557.1 - 5.2e-21 75.3 0.0 1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OEU17557.1 - 0.00018 21.3 1.7 0.0024 17.6 0.1 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OEU17557.1 - 0.002 18.2 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 OEU17557.1 - 0.0094 15.4 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OEU17557.1 - 0.027 14.4 0.2 0.057 13.3 0.0 1.8 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OEU17557.1 - 0.034 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_trans_4_2 PF13477.6 OEU17557.1 - 0.13 12.2 0.0 0.44 10.6 0.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase 4-like GFO_IDH_MocA PF01408.22 OEU17558.1 - 2.6e-14 54.1 1.0 2.7e-13 50.8 0.4 2.5 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 OEU17558.1 - 0.13 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sec23_trunk PF04811.15 OEU17559.1 - 1.7e-70 237.3 0.0 2.7e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OEU17559.1 - 4.6e-21 74.6 0.0 7.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OEU17559.1 - 1.3e-15 57.9 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OEU17559.1 - 3.6e-14 52.5 4.4 7e-14 51.6 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OEU17559.1 - 7.7e-09 35.3 0.0 2.3e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Yippee-Mis18 PF03226.14 OEU17559.1 - 0.18 12.1 0.3 0.33 11.2 0.3 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HMA PF00403.26 OEU17560.1 - 8.4e-17 61.4 0.6 9e-17 61.3 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 OEU17560.1 - 0.00087 19.3 0.1 0.001 19.1 0.1 1.2 1 0 0 1 1 1 1 Alpha-lytic protease prodomain NapD PF03927.13 OEU17560.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 NapD protein UPF0020 PF01170.18 OEU17561.1 - 0.0014 18.4 0.0 0.042 13.5 0.0 2.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 OEU17561.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase CALCOCO1 PF07888.11 OEU17563.1 - 0.00061 18.8 30.1 0.00092 18.2 30.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 OEU17563.1 - 1.3 8.7 37.7 1.7 8.4 7.2 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 OEU17563.1 - 3.3 5.5 11.9 4.6 5.0 11.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 OEU17563.1 - 3.6 6.4 8.7 5.1 5.9 8.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Sugar_tr PF00083.24 OEU17564.1 - 8.8e-20 71.0 20.7 3.5e-10 39.3 1.9 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 OEU17564.1 - 3e-19 69.2 21.0 1.9e-12 46.8 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3290 PF11694.8 OEU17564.1 - 0.17 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Glyco_transf_8 PF01501.20 OEU17565.1 - 2.7e-16 59.9 2.9 2.7e-16 59.9 2.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 OEU17565.1 - 0.0001 21.8 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 HHH_8 PF14716.6 OEU17567.1 - 4.3e-08 33.4 0.1 8.5e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PADR1 PF08063.12 OEU17567.1 - 2.7e-05 23.8 0.1 5.8e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 PADR1 (NUC008) domain Mcm10 PF09332.11 OEU17567.1 - 0.025 14.0 6.3 0.064 12.7 6.3 1.6 1 0 0 1 1 1 0 Mcm10 replication factor GET2 PF08690.10 OEU17567.1 - 0.044 13.5 1.7 0.087 12.5 1.7 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 LuxS PF02664.15 OEU17567.1 - 0.091 12.4 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) Evr1_Alr PF04777.13 OEU17568.1 - 4.5e-29 100.9 2.5 5.9e-29 100.5 2.5 1.1 1 0 0 1 1 1 1 Erv1 / Alr family DUF4080 PF13311.6 OEU17568.1 - 0.027 14.7 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Kelch_4 PF13418.6 OEU17570.1 - 5.4e-24 83.9 4.2 5.4e-07 29.5 0.1 4.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OEU17570.1 - 3.8e-22 78.1 8.7 4.3e-05 23.7 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OEU17570.1 - 1.8e-20 72.4 0.0 4.6e-07 29.7 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OEU17570.1 - 6.9e-14 51.6 1.1 2.5e-05 24.4 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OEU17570.1 - 1.5e-13 50.1 3.9 1.4e-06 27.8 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OEU17570.1 - 8.8e-11 41.3 1.6 0.0021 18.0 0.0 4.6 4 1 0 4 4 4 3 Kelch motif RNA_pol_Rpb4 PF03874.16 OEU17571.1 - 3.4e-09 37.1 0.7 4.6e-09 36.6 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 GAT PF03127.14 OEU17571.1 - 0.0046 17.2 1.5 0.0089 16.3 1.5 1.5 1 0 0 1 1 1 1 GAT domain KASH_CCD PF14662.6 OEU17571.1 - 0.0084 16.0 2.5 0.011 15.5 2.5 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fzo_mitofusin PF04799.13 OEU17571.1 - 0.017 14.7 0.8 0.022 14.3 0.8 1.1 1 0 0 1 1 1 0 fzo-like conserved region UPF0449 PF15136.6 OEU17571.1 - 0.037 14.5 1.0 0.056 13.9 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 rve_3 PF13683.6 OEU17571.1 - 0.049 13.4 0.2 0.09 12.6 0.2 1.4 1 0 0 1 1 1 0 Integrase core domain Topoisom_I PF01028.20 OEU17572.1 - 3.6e-87 291.4 9.2 3.6e-87 291.4 9.2 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 OEU17572.1 - 2.5e-78 262.4 0.3 2.5e-78 262.4 0.3 2.5 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 OEU17572.1 - 1.5e-35 121.0 0.8 5.2e-35 119.2 0.8 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Methyltransf_16 PF10294.9 OEU17573.1 - 2.3e-16 60.0 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OEU17573.1 - 7.8e-08 32.9 0.0 4.7e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OEU17573.1 - 3e-06 26.9 0.1 4.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OEU17573.1 - 8.3e-06 26.5 1.1 0.0061 17.3 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 OEU17573.1 - 0.00029 20.7 0.0 0.00056 19.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU17573.1 - 0.0036 17.9 0.0 0.017 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OEU17573.1 - 0.025 14.2 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Senescence PF06911.12 OEU17574.1 - 3.1e-17 63.5 8.2 3.1e-17 63.5 8.2 1.7 2 0 0 2 2 2 1 Senescence-associated protein GARP PF16731.5 OEU17574.1 - 0.0067 16.1 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma MCM PF00493.23 OEU17576.1 - 1.5e-99 331.7 0.0 2.5e-99 330.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OEU17576.1 - 3.8e-28 97.8 0.1 9.8e-28 96.5 0.1 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OEU17576.1 - 2.8e-21 75.7 0.8 4.9e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain AAA_5 PF07728.14 OEU17576.1 - 1.7e-08 34.5 0.0 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU17576.1 - 8.1e-08 31.9 0.1 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OEU17576.1 - 0.0053 16.6 0.0 0.02 14.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 OEU17576.1 - 0.04 14.6 0.6 0.18 12.5 0.1 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 OEU17576.1 - 0.053 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 OEU17576.1 - 0.095 13.1 0.1 0.4 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DZR PF12773.7 OEU17576.1 - 0.14 12.2 0.3 0.25 11.4 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF3245 PF11595.8 OEU17576.1 - 0.93 10.0 2.9 2.1 8.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Swi3 PF07962.12 OEU17577.1 - 2.2e-07 30.7 0.0 4.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 CENP-B_dimeris PF09026.10 OEU17578.1 - 0.03 14.7 12.4 1.5 9.3 1.6 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SUIM_assoc PF16619.5 OEU17578.1 - 0.033 14.2 5.4 0.29 11.2 0.5 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 OEU17578.1 - 6 6.4 8.8 2.1 7.9 1.6 2.6 2 0 0 2 2 2 0 Spt20 family KASH_CCD PF14662.6 OEU17579.1 - 0.0038 17.1 1.5 0.0049 16.7 1.5 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TMEM52 PF14979.6 OEU17579.1 - 0.034 14.1 1.8 0.14 12.1 0.7 1.9 1 1 1 2 2 2 0 Transmembrane 52 Late_protein_L2 PF00513.18 OEU17579.1 - 0.037 13.1 2.7 0.039 13.0 2.7 1.0 1 0 0 1 1 1 0 Late Protein L2 DivIC PF04977.15 OEU17579.1 - 0.039 13.7 0.6 0.083 12.7 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator HBM PF16591.5 OEU17579.1 - 0.058 12.8 0.3 0.084 12.3 0.2 1.3 1 1 0 1 1 1 0 Helical bimodular sensor domain DUF3450 PF11932.8 OEU17579.1 - 0.06 12.6 0.6 0.069 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Desmo_N PF06771.11 OEU17579.1 - 0.077 13.4 1.1 0.68 10.3 0.2 2.1 1 1 1 2 2 2 0 Viral Desmoplakin N-terminus DivIVA PF05103.13 OEU17579.1 - 0.08 13.0 1.2 0.13 12.4 0.2 1.8 2 0 0 2 2 2 0 DivIVA protein DUF1664 PF07889.12 OEU17579.1 - 0.1 12.6 1.1 0.16 12.0 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 OEU17579.1 - 0.14 12.5 3.8 0.23 11.9 3.0 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Asp_protease_2 PF13650.6 OEU17580.1 - 7e-14 52.2 0.5 1.3e-08 35.3 0.1 2.6 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 OEU17580.1 - 5e-09 36.6 0.0 0.0023 18.5 0.1 3.4 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease DUF1319 PF07028.11 OEU17581.1 - 0.0078 16.4 0.5 0.024 14.9 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1319) DUF1690 PF07956.11 OEU17581.1 - 0.073 13.5 1.1 0.11 12.9 0.2 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Spc7 PF08317.11 OEU17581.1 - 0.1 11.4 2.7 0.14 11.0 2.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1400 PF07176.11 OEU17581.1 - 0.12 12.7 0.3 1.7 8.9 0.2 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) FlaC_arch PF05377.11 OEU17581.1 - 0.23 11.9 6.2 1.8 9.0 0.2 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 OEU17581.1 - 0.25 11.1 1.0 0.77 9.6 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 OEU17581.1 - 0.29 11.6 4.2 1.6 9.3 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OEU17581.1 - 0.76 9.8 3.5 6.3 6.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pro_isomerase PF00160.21 OEU17582.1 - 1.1e-42 146.0 0.1 1.4e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPP PF06550.11 OEU17583.1 - 0.21 11.0 7.8 0.31 10.5 7.8 1.2 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease DUF3413 PF11893.8 OEU17583.1 - 4.5 6.4 10.7 1.1 8.4 6.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) NAD_binding_10 PF13460.6 OEU17585.1 - 1.1e-31 110.2 0.0 1.7e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OEU17585.1 - 6.6e-10 38.9 0.0 9.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OEU17585.1 - 2.7e-08 33.6 0.1 4.1e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OEU17585.1 - 0.00014 21.4 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU17585.1 - 0.00026 20.1 0.7 0.00046 19.3 0.5 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OEU17585.1 - 0.041 14.3 0.1 0.31 11.5 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ank PF00023.30 OEU17586.1 - 2e-07 31.1 4.1 0.53 10.8 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 OEU17586.1 - 8.3e-07 29.5 0.0 0.046 14.3 0.0 3.4 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU17586.1 - 2.9e-06 27.7 0.1 0.93 10.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU17586.1 - 6.5e-06 26.3 0.3 0.69 10.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU17586.1 - 0.00014 22.0 2.0 22 6.1 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat K_trans PF02705.16 OEU17586.1 - 0.22 10.0 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter V-SNARE_C PF12352.8 OEU17587.1 - 3.1e-08 33.8 0.2 7.4e-08 32.6 0.2 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OEU17587.1 - 0.0047 16.8 0.1 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 OEU17587.1 - 0.028 13.8 2.3 0.036 13.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CBS PF00571.28 OEU17588.1 - 1.2e-10 41.7 0.1 0.00027 21.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain SpoIIE PF07228.12 OEU17588.1 - 7.7e-10 39.0 0.0 9.3e-08 32.2 0.0 3.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OEU17588.1 - 0.00012 21.8 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C DUF4527 PF15030.6 OEU17589.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Sad1_UNC PF07738.13 OEU17590.1 - 7.4e-18 64.8 0.2 3.6e-17 62.6 0.0 2.0 1 1 1 2 2 2 1 Sad1 / UNC-like C-terminal BAR_3 PF16746.5 OEU17590.1 - 0.048 13.4 3.0 1.9 8.1 0.8 2.6 3 0 0 3 3 3 0 BAR domain of APPL family DUF4304 PF14137.6 OEU17590.1 - 0.096 12.9 0.6 0.65 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) Methyltransf_21 PF05050.12 OEU17591.1 - 2.1e-15 57.2 0.0 2.7e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_hydro_12 PF01670.16 OEU17592.1 - 0.066 13.2 0.2 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 12 Peptidase_S49_N PF08496.10 OEU17592.1 - 0.14 12.2 3.5 0.23 11.5 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Apt1 PF10351.9 OEU17592.1 - 1.8 7.3 16.8 3.6 6.4 16.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Trp_Tyr_perm PF03222.13 OEU17593.1 - 2.7e-73 247.3 9.9 3.7e-73 246.8 9.9 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 OEU17593.1 - 3.1e-08 32.7 13.7 1.1e-07 31.0 13.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Ceramidase PF05875.12 OEU17593.1 - 0.0035 16.8 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Ceramidase Bromodomain PF00439.25 OEU17594.1 - 1.4e-18 66.7 0.2 2.3e-18 66.0 0.2 1.3 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OEU17594.1 - 2.6e-11 43.8 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU17594.1 - 3.9e-08 33.3 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU17594.1 - 4.5e-08 33.4 0.0 9.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU17594.1 - 0.022 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF3965 PF13112.6 OEU17594.1 - 0.053 12.7 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) Acetyltransf_3 PF13302.7 OEU17594.1 - 0.15 12.8 0.0 0.27 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Y_phosphatase2 PF03162.13 OEU17595.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Aminotran_3 PF00202.21 OEU17597.1 - 1.8e-64 217.9 0.0 2.2e-44 151.8 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III Beta_elim_lyase PF01212.21 OEU17597.1 - 0.16 11.2 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Beta-eliminating lyase ADK PF00406.22 OEU17598.1 - 4.1e-36 124.3 0.0 5.1e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU17598.1 - 2e-20 73.6 0.5 3.9e-20 72.7 0.5 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU17598.1 - 1.9e-09 38.2 0.2 4.1e-09 37.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU17598.1 - 4.4e-08 33.4 0.0 6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU17598.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 OEU17598.1 - 0.063 13.2 0.1 8.6 6.2 0.1 2.1 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 OEU17598.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OEU17598.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rib_5-P_isom_A PF06026.14 OEU17599.1 - 6.3e-66 221.2 0.1 8.7e-66 220.8 0.1 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) VCBS PF13517.6 OEU17600.1 - 2.1e-11 44.2 5.7 0.00012 22.6 0.5 4.6 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OEU17600.1 - 1.5e-06 28.2 9.2 0.062 13.4 1.2 3.7 3 0 0 3 3 3 3 FG-GAP repeat LPD11 PF18824.1 OEU17600.1 - 0.00029 20.9 15.5 0.15 12.1 1.3 4.5 1 1 2 3 3 3 3 Large polyvalent protein-associated domain 11 PQQ PF01011.21 OEU17600.1 - 0.0046 16.8 0.0 0.34 10.9 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat DUF261 PF03196.13 OEU17600.1 - 1.7 8.8 14.5 28 4.8 0.3 4.8 1 1 2 4 4 4 0 Protein of unknown function, DUF261 adh_short PF00106.25 OEU17601.1 - 0.0014 18.1 0.2 0.15 11.5 0.0 2.9 2 1 1 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 OEU17601.1 - 0.011 15.2 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DnaJ_C PF01556.18 OEU17602.1 - 1.7e-40 138.5 0.0 2.7e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OEU17602.1 - 3.1e-22 78.5 1.5 5.9e-22 77.6 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OEU17602.1 - 4.6e-12 46.1 17.6 9e-12 45.2 17.6 1.5 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.7 OEU17602.1 - 0.17 11.9 9.9 0.7 10.0 9.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon Anti-TRAP PF15777.5 OEU17602.1 - 1.6 8.7 17.5 3.6 7.6 5.3 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 OEU17602.1 - 2.1 8.0 5.6 0.94 9.1 0.6 2.1 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_15 PF17032.5 OEU17602.1 - 7.7 7.3 7.4 18 6.2 7.4 1.7 1 1 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 OEU17602.1 - 8.9 6.4 9.5 11 6.1 2.5 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIA PF03153.13 OEU17603.1 - 0.0014 18.7 7.9 0.0014 18.7 7.9 2.5 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit NPR1_like_C PF12313.8 OEU17603.1 - 1.9 8.0 5.8 0.46 10.0 0.4 2.5 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal IF2_N PF04760.15 OEU17604.1 - 0.019 14.7 0.2 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DDE_Tnp_1_7 PF13843.6 OEU17605.1 - 7.4e-15 55.1 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DUF333 PF03891.15 OEU17606.1 - 0.0097 16.1 0.7 0.039 14.2 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF333) SET PF00856.28 OEU17607.1 - 7e-09 36.3 0.1 1.4e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 SET domain RNase_HII PF01351.18 OEU17608.1 - 5.6e-25 88.3 0.0 8.2e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII LINES_C PF14695.6 OEU17608.1 - 0.011 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Lines C-terminus Ca_bind_SSO6904 PF18249.1 OEU17608.1 - 0.19 12.1 1.3 0.53 10.7 0.2 2.2 2 0 0 2 2 2 0 Calcium binding protein SSO6904 Proteasome PF00227.26 OEU17610.1 - 2.9e-11 43.2 0.1 1.8e-10 40.6 0.1 2.1 2 1 0 2 2 2 1 Proteasome subunit Optomotor-blind PF11078.8 OEU17611.1 - 0.081 13.5 0.4 0.15 12.7 0.4 1.4 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region Flavodoxin_5 PF12724.7 OEU17611.1 - 0.18 12.0 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain MFS_1 PF07690.16 OEU17613.1 - 3.8e-22 78.7 45.9 2e-16 59.9 16.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU17613.1 - 2.2e-10 40.0 7.3 2.2e-10 40.0 7.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3128 PF11326.8 OEU17614.1 - 1.5e-12 47.7 0.2 2.2e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF5470 PF17564.2 OEU17614.1 - 0.1 12.8 1.2 0.19 11.9 1.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Slu7 PF11708.8 OEU17616.1 - 3.1e-66 223.9 1.8 3.1e-66 223.9 1.8 2.1 2 0 0 2 2 2 2 Pre-mRNA splicing Prp18-interacting factor Trypsin_2 PF13365.6 OEU17617.1 - 4.1e-31 108.9 0.2 1.9e-30 106.7 0.1 2.2 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 OEU17617.1 - 7.4e-11 42.2 0.1 1.6e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 OEU17617.1 - 1.6e-10 41.2 0.0 2.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 OEU17617.1 - 4.9e-05 23.1 1.9 0.06 13.2 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OEU17617.1 - 0.056 13.8 0.8 0.92 9.9 0.8 2.5 1 1 0 1 1 1 0 PDZ domain A_deaminase PF00962.22 OEU17618.1 - 1.4e-45 156.1 0.0 2.2e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-RING_2 PF13639.6 OEU17618.1 - 0.78 10.1 0.1 0.78 10.1 0.1 2.6 3 0 0 3 3 3 0 Ring finger domain GreA_GreB PF01272.19 OEU17619.1 - 0.023 14.6 0.0 6.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term DUF3450 PF11932.8 OEU17619.1 - 0.39 10.0 3.8 0.71 9.1 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SURF6 PF04935.12 OEU17620.1 - 1.1e-24 87.3 43.9 1.1e-24 87.3 43.9 2.3 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 OEU17620.1 - 4.7e-15 55.9 0.8 4.7e-15 55.9 0.8 5.4 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 Abhydrolase_1 PF00561.20 OEU17621.1 - 5e-16 59.1 0.3 2.9e-08 33.7 0.3 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Methyltransf_2 PF00891.18 OEU17621.1 - 3.9e-13 49.2 0.0 9e-13 48.0 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Hydrolase_4 PF12146.8 OEU17621.1 - 3.6e-11 42.8 0.8 1.5e-10 40.7 0.8 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 OEU17621.1 - 4.4e-10 40.1 0.0 3.1e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation2 PF16864.5 OEU17621.1 - 6.9e-10 38.8 0.0 1.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_11 PF08241.12 OEU17621.1 - 2.6e-09 37.6 0.0 7.8e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU17621.1 - 2.9e-09 37.6 0.0 1.1e-08 35.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU17621.1 - 7.5e-09 35.6 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU17621.1 - 1.2e-08 34.9 0.0 7.7e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_6 PF12697.7 OEU17621.1 - 4.3e-08 34.0 0.1 8.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.18 OEU17621.1 - 2.6e-06 26.9 0.0 5.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OEU17621.1 - 1.2e-05 25.2 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_PK PF05891.12 OEU17621.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 OEU17621.1 - 0.0035 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_S9 PF00326.21 OEU17621.1 - 0.011 15.2 0.6 0.3 10.6 0.6 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1100 PF06500.11 OEU17621.1 - 0.012 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) MTS PF05175.14 OEU17621.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 OEU17621.1 - 0.035 15.1 0.3 0.12 13.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Abhydrolase_4 PF08386.10 OEU17621.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein CMAS PF02353.20 OEU17621.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BAAT_C PF08840.11 OEU17621.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF155 PF02582.14 OEU17622.1 - 1.9e-22 80.2 0.1 3.5e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SET PF00856.28 OEU17624.1 - 4.7e-05 23.9 8.3 5.2e-05 23.7 4.0 2.7 2 1 0 2 2 2 1 SET domain Pheromone PF08015.11 OEU17624.1 - 0.63 11.1 4.1 15 6.7 0.6 3.2 2 1 0 2 2 2 0 Fungal mating-type pheromone DUF4834 PF16118.5 OEU17624.1 - 5.2 8.1 8.3 13 6.8 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MRI PF15325.6 OEU17624.1 - 8.5 7.5 9.4 2 9.6 1.7 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection Glyco_transf_25 PF01755.17 OEU17625.1 - 2.1e-18 66.9 0.0 3e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pkinase PF00069.25 OEU17627.1 - 3e-09 36.7 0.0 6e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17627.1 - 0.00032 20.1 0.0 0.00099 18.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 OEU17628.1 - 2.5e-21 75.3 0.0 2.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OEU17628.1 - 0.0065 16.3 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 OEU17628.1 - 0.007 16.4 0.0 0.0089 16.1 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 OEU17628.1 - 0.045 13.8 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 RRM_7 PF16367.5 OEU17628.1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 OEU17629.1 - 3.3e-38 129.3 0.0 8.4e-20 70.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OEU17629.1 - 0.00051 20.0 0.0 0.74 9.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 OEU17629.1 - 0.01 15.9 0.5 2.1 8.5 0.1 2.8 2 1 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 OEU17629.1 - 0.034 13.7 0.0 6.6 6.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OEU17629.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 OEU17629.1 - 0.13 12.2 0.0 6.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif NADH-u_ox-rdase PF10785.9 OEU17630.1 - 1.4e-12 48.1 0.4 1.6e-12 47.9 0.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Gtr1_RagA PF04670.12 OEU17631.1 - 2.7e-91 305.0 0.0 3.3e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OEU17631.1 - 2.1e-07 30.7 0.0 4.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU17631.1 - 2.8e-07 30.8 0.0 8.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU17631.1 - 4.1e-07 29.6 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU17631.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ADD_DNMT3 PF17980.1 OEU17631.1 - 0.0037 17.2 3.3 0.067 13.2 0.6 3.1 3 0 0 3 3 3 1 Cysteine rich ADD domain in DNMT3 LT-IIB PF06453.11 OEU17631.1 - 0.056 13.3 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) G-alpha PF00503.20 OEU17631.1 - 0.12 11.5 1.6 3.6 6.6 0.1 2.8 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OEU17631.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MatE PF01554.18 OEU17632.1 - 7.6e-37 126.4 33.5 2.6e-23 82.4 9.7 3.0 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OEU17632.1 - 3e-07 30.6 3.2 3e-07 30.6 3.2 4.3 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Guanylate_cyc PF00211.20 OEU17633.1 - 3.3e-14 52.9 0.0 5.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain QslA_E PF18226.1 OEU17633.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E HTH_29 PF13551.6 OEU17634.1 - 1.3e-06 28.3 8.0 0.0055 16.7 0.0 3.6 3 1 0 3 3 3 2 Winged helix-turn helix HTH_23 PF13384.6 OEU17634.1 - 9e-05 22.2 4.5 0.0014 18.4 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain DisA-linker PF10635.9 OEU17634.1 - 0.00031 20.5 1.8 0.022 14.5 0.2 2.5 2 0 0 2 2 2 2 DisA bacterial checkpoint controller linker region HTH_24 PF13412.6 OEU17634.1 - 0.00078 19.0 0.1 0.0047 16.4 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 OEU17634.1 - 0.0011 19.0 1.0 0.16 12.1 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain DUF4031 PF13223.6 OEU17634.1 - 0.0035 17.5 0.1 3.5 7.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4031) Nod1 PF17114.5 OEU17634.1 - 0.04 14.1 0.4 0.071 13.3 0.4 1.4 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 HTH_26 PF13443.6 OEU17634.1 - 0.072 13.5 1.1 9.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Guanylate_cyc PF00211.20 OEU17635.1 - 6e-11 42.3 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain IQ PF00612.27 OEU17635.1 - 0.023 14.5 0.2 0.064 13.1 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif CshA_NR2 PF18651.1 OEU17637.1 - 0.048 12.9 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Surface adhesin CshA non-repetitive domain 2 DUF2076 PF09849.9 OEU17637.1 - 0.054 13.5 0.6 0.062 13.3 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1499 PF07386.11 OEU17638.1 - 2.5e-15 57.0 0.1 5.3e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) N2227 PF07942.12 OEU17639.1 - 3.7e-48 164.1 0.0 5.6e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 OEU17639.1 - 1.4e-06 28.2 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU17639.1 - 8.9e-05 23.1 0.0 0.64 10.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OEU17639.1 - 0.0001 23.0 0.0 0.027 15.2 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU17639.1 - 0.00015 22.4 0.1 0.00098 19.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Peptidase_S10 PF00450.22 OEU17640.1 - 2e-91 307.5 0.0 2.6e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sulfotransfer_3 PF13469.6 OEU17642.1 - 2.3e-07 31.4 0.0 6.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 OEU17642.1 - 3.7e-05 23.7 0.0 0.00015 21.6 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 OEU17642.1 - 0.0012 18.4 0.5 0.018 14.5 0.5 2.2 1 1 0 1 1 1 1 Sulfotransferase domain zf-3CxxC_2 PF17180.4 OEU17643.1 - 3 8.7 8.2 2.7 8.8 0.4 3.2 3 0 0 3 3 3 0 Zinc-binding domain A2L_zn_ribbon PF08792.10 OEU17643.1 - 6.3 6.6 7.4 21 5.0 0.6 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain BTB PF00651.31 OEU17644.1 - 1.8e-10 41.0 0.1 5.6e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Gln_deamidase_2 PF18626.1 OEU17644.1 - 0.088 13.1 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Glutaminase Methyltransf_16 PF10294.9 OEU17645.1 - 2.6e-14 53.3 0.8 2.9e-13 49.9 0.8 2.2 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OEU17645.1 - 0.00016 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OEU17645.1 - 0.0052 17.5 0.1 0.071 13.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain UPF0220 PF05255.11 OEU17646.1 - 0.031 13.8 2.3 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) TFCD_C PF12612.8 OEU17647.1 - 8.2e-37 126.9 0.1 3.1e-36 125.0 0.1 2.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 OEU17647.1 - 7.4e-07 29.5 2.3 0.32 11.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 OEU17647.1 - 8.8e-06 25.6 13.5 0.18 12.1 0.0 8.6 9 0 0 9 9 9 1 HEAT repeat Cnd1 PF12717.7 OEU17647.1 - 5.1e-05 23.4 0.1 7.1 6.6 0.0 5.3 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 OEU17647.1 - 0.0088 16.6 0.0 0.5 11.2 0.0 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat DUF1292 PF06949.11 OEU17647.1 - 0.14 13.1 0.1 0.94 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) Tubulin PF00091.25 OEU17649.1 - 2.2e-69 233.6 0.0 5.1e-69 232.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OEU17649.1 - 3.4e-38 130.6 0.1 5.1e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OEU17649.1 - 3.7e-05 24.0 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OEU17649.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain CaMKII_AD PF08332.10 OEU17650.1 - 6.9e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 OEU17650.1 - 8.7e-09 35.7 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OEU17650.1 - 2.6e-06 28.0 0.0 3.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OEU17650.1 - 6.5e-05 23.3 0.1 0.00012 22.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) Pro_dh PF01619.18 OEU17651.1 - 2.5e-80 270.2 0.0 6e-80 268.9 0.0 1.5 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_1 PF00036.32 OEU17651.1 - 9.4e-08 31.1 0.5 0.00013 21.3 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU17651.1 - 1.4e-06 27.7 0.5 0.0021 17.8 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU17651.1 - 2.3e-06 28.0 0.4 0.013 15.9 0.1 3.2 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU17651.1 - 0.00016 21.0 0.2 0.00016 21.0 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OEU17651.1 - 0.016 15.1 0.2 0.043 13.7 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain pair O-FucT PF10250.9 OEU17652.1 - 1.6e-50 172.8 3.1 2.1e-50 172.3 3.1 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AA_permease_2 PF13520.6 OEU17653.1 - 8.2e-36 123.7 30.3 9.3e-36 123.6 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OEU17653.1 - 3.5e-09 35.8 27.7 3.6e-08 32.4 27.7 2.5 1 1 0 1 1 1 1 Amino acid permease SR-25 PF10500.9 OEU17654.1 - 0.13 11.9 4.5 0.22 11.1 4.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein R3H PF01424.22 OEU17656.1 - 7.4e-14 51.5 0.1 2.8e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 R3H domain Caldesmon PF02029.15 OEU17656.1 - 0.00089 18.1 11.2 0.00089 18.1 11.2 4.1 4 0 0 4 4 4 3 Caldesmon ThrE PF06738.12 OEU17657.1 - 3.5e-12 46.2 7.0 3.5e-12 46.2 7.0 2.1 3 0 0 3 3 3 1 Putative threonine/serine exporter TYW3 PF02676.14 OEU17658.1 - 5.7e-38 130.4 0.0 8.9e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 OEU17658.1 - 2.9e-22 79.4 0.0 4.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 OEU17658.1 - 0.00092 19.9 0.0 0.0028 18.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OEU17658.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 OEU17658.1 - 0.092 13.4 0.0 0.57 10.9 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain CTD_bind PF04818.13 OEU17659.1 - 1.9e-14 54.2 0.0 6.8e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RPT PF13446.6 OEU17659.1 - 0.063 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein FYDLN_acid PF09538.10 OEU17659.1 - 5.4 7.7 16.4 4.6 8.0 6.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PBP_sp32 PF07222.12 OEU17659.1 - 8.4 5.8 8.1 17 4.7 8.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Cyclin_N PF00134.23 OEU17660.1 - 1e-08 35.0 2.6 1.1e-07 31.7 2.6 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 OEU17660.1 - 0.11 12.5 0.5 0.71 10.0 0.0 2.5 3 0 0 3 3 3 0 Transcription factor TFIIB repeat FAM60A PF15396.6 OEU17660.1 - 6.2 6.8 15.0 0.95 9.4 0.9 3.2 2 2 0 2 2 2 0 Protein Family FAM60A IMUP PF15761.5 OEU17661.1 - 0.17 12.6 5.2 0.2 12.4 5.2 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 OEU17661.1 - 0.28 10.7 8.3 0.33 10.5 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Caskin-tail PF16632.5 OEU17663.1 - 0.13 12.7 0.4 13 6.2 0.0 2.7 3 0 0 3 3 3 0 C-terminal region of Caskin RNase_T PF00929.24 OEU17665.1 - 8.7e-08 32.9 0.0 1.6e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Nuf2 PF03800.14 OEU17666.1 - 2.1e-30 105.7 0.1 5.5e-30 104.3 0.1 1.7 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 OEU17666.1 - 2.6e-07 30.7 24.6 2.6e-07 30.7 24.6 3.3 2 1 1 3 3 3 1 Designed helical repeat protein 10 domain HTH_19 PF12844.7 OEU17666.1 - 0.017 15.1 0.1 0.28 11.2 0.1 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain DUF465 PF04325.13 OEU17666.1 - 0.032 14.3 2.2 0.032 14.3 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Spc7 PF08317.11 OEU17666.1 - 0.15 11.0 49.3 0.069 12.0 30.0 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Img2 PF05046.14 OEU17666.1 - 0.33 11.3 1.4 0.67 10.3 0.2 2.1 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Fez1 PF06818.15 OEU17666.1 - 0.62 10.5 46.9 1.5 9.2 23.9 2.5 1 1 2 3 3 3 0 Fez1 Leu_zip PF15294.6 OEU17666.1 - 1 8.8 41.5 4.6 6.7 20.6 2.2 1 1 1 2 2 2 0 Leucine zipper DUF4407 PF14362.6 OEU17666.1 - 6.8 6.0 38.9 2.4 7.4 19.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 OEU17666.1 - 8.1 6.7 32.1 0.18 12.1 12.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) TFIIA PF03153.13 OEU17667.1 - 5e-05 23.5 12.3 5.6e-05 23.3 12.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 OEU17667.1 - 0.005 17.1 6.4 0.14 12.5 0.0 2.3 2 0 0 2 2 2 1 Orf78 (ac78) Amnionless PF14828.6 OEU17667.1 - 0.019 13.8 4.6 0.025 13.4 4.6 1.1 1 0 0 1 1 1 0 Amnionless DUF5305 PF17231.2 OEU17667.1 - 0.026 13.9 0.3 0.026 13.9 0.3 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Presenilin PF01080.17 OEU17667.1 - 0.051 12.4 7.7 0.075 11.8 7.7 1.3 1 0 0 1 1 1 0 Presenilin Herpes_UL32 PF06070.11 OEU17667.1 - 0.11 10.2 7.0 0.14 9.9 7.0 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Macoilin PF09726.9 OEU17667.1 - 0.12 10.9 17.8 0.15 10.6 17.8 1.0 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 OEU17667.1 - 0.13 12.2 15.2 1.3 8.9 15.1 2.3 1 1 0 1 1 1 0 TMEM154 protein family ALMT PF11744.8 OEU17667.1 - 0.62 8.8 5.7 0.81 8.4 5.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PNISR PF15996.5 OEU17667.1 - 0.73 10.1 12.5 1.1 9.6 12.5 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Miga PF10265.9 OEU17667.1 - 1.3 8.0 7.2 1.6 7.6 7.2 1.0 1 0 0 1 1 1 0 Mitoguardin SLC12 PF03522.15 OEU17667.1 - 3.1 6.7 12.5 4.1 6.3 12.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SOG2 PF10428.9 OEU17667.1 - 6.6 5.8 18.3 9.4 5.3 18.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1035 PF06281.12 OEU17667.1 - 6.6 6.8 11.2 4.9 7.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) Activator_LAG-3 PF11498.8 OEU17667.1 - 7 5.5 28.2 10 5.0 28.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Roughex PF06020.11 OEU17667.1 - 9.9 5.1 10.8 13 4.8 10.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ApbA_C PF08546.11 OEU17670.1 - 6.3e-29 100.7 0.2 8.4e-29 100.3 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MatE PF01554.18 OEU17671.1 - 7.8e-21 74.4 5.7 7.8e-21 74.4 5.7 3.5 3 1 0 3 3 3 1 MatE Polysacc_synt_C PF14667.6 OEU17671.1 - 1.2e-08 35.2 10.7 1.2e-08 35.2 10.7 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Borrelia_P13 PF05628.12 OEU17671.1 - 0.002 18.1 2.8 0.26 11.3 0.3 3.1 2 1 1 3 3 3 2 Borrelia membrane protein P13 DUF3341 PF11821.8 OEU17671.1 - 0.015 15.0 0.5 0.06 13.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Hexapep PF00132.24 OEU17673.1 - 2.5e-09 36.5 7.8 4.9e-05 22.9 0.0 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OEU17673.1 - 0.073 12.8 8.4 0.17 11.6 0.0 4.2 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Sde2_N_Ubi PF13019.6 OEU17674.1 - 0.027 14.3 0.1 0.09 12.6 0.2 1.9 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Glyco_transf_15 PF01793.16 OEU17674.1 - 0.36 10.0 8.1 26 3.9 0.0 3.1 2 1 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.25 OEU17675.1 - 3.3e-51 174.2 0.0 4.6e-50 170.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17675.1 - 1.3e-31 109.9 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU17675.1 - 0.00014 20.8 0.0 0.0002 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU17675.1 - 0.0013 18.7 0.0 0.0075 16.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU17675.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OEU17675.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_6 PF13516.6 OEU17676.1 - 2.8e-07 30.0 3.8 0.0018 18.2 0.4 3.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 OEU17676.1 - 0.01 16.2 0.2 0.035 14.5 0.2 1.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 OEU17678.1 - 2.8e-09 36.9 14.5 5.9e-09 35.9 14.5 1.6 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 OEU17678.1 - 0.073 13.7 0.1 1.1 9.9 0.0 2.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) UBA_3 PF09288.10 OEU17678.1 - 0.12 12.2 3.5 0.38 10.6 0.0 2.7 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain MMR_HSR1 PF01926.23 OEU17679.1 - 7.5e-24 84.0 0.0 1.6e-23 82.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU17679.1 - 3.2e-09 36.5 0.0 1.6e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP1_OBG PF01018.22 OEU17679.1 - 3.5e-06 26.7 0.3 6.3e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 GTP1/OBG Dynamin_N PF00350.23 OEU17679.1 - 0.00015 21.9 0.0 0.75 9.8 0.0 2.7 1 1 2 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 OEU17679.1 - 0.0002 20.9 0.0 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OEU17679.1 - 0.0029 16.6 2.3 0.48 9.4 1.2 2.4 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 OEU17679.1 - 0.027 14.3 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4813 PF16072.5 OEU17679.1 - 0.055 13.1 0.2 0.096 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) MMR_HSR1_Xtn PF16897.5 OEU17679.1 - 0.099 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OEU17679.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L3 PF00297.22 OEU17680.1 - 4.2e-143 476.8 10.4 4.8e-143 476.6 10.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Pox_D5 PF03288.16 OEU17680.1 - 0.16 12.5 1.9 0.36 11.3 0.1 2.3 2 0 0 2 2 2 0 Poxvirus D5 protein-like 2OG-FeII_Oxy_3 PF13640.6 OEU17681.1 - 0.025 15.5 0.0 0.046 14.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Semialdhyde_dh PF01118.24 OEU17682.1 - 2.3e-09 37.7 0.2 1.8e-08 34.9 0.0 2.3 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pro-kuma_activ PF09286.11 OEU17683.1 - 1.1e-09 38.7 0.0 2.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OEU17683.1 - 0.017 14.4 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Subtilase family SNARE PF05739.19 OEU17684.1 - 4.4e-15 55.4 1.4 3e-14 52.7 0.2 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OEU17684.1 - 2.7e-08 33.7 6.8 1.6e-07 31.2 6.8 2.0 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 OEU17684.1 - 0.0075 16.6 4.4 0.031 14.6 0.5 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Tropomyosin PF00261.20 OEU17684.1 - 0.027 13.9 3.2 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 Tropomyosin NBD94 PF16830.5 OEU17684.1 - 0.047 14.1 0.3 0.57 10.6 0.0 2.6 2 1 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH XLF PF09302.11 OEU17684.1 - 0.061 13.5 0.3 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Pox_EPC_I2-L1 PF12575.8 OEU17684.1 - 0.11 12.7 0.3 0.27 11.5 0.1 1.7 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Baculo_PEP_C PF04513.12 OEU17684.1 - 0.42 10.7 3.1 4.2 7.4 0.7 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 OEU17684.1 - 0.45 11.3 5.7 21 5.9 4.5 2.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF16 PF01519.16 OEU17684.1 - 0.46 11.0 6.6 0.44 11.1 3.1 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 Synaptobrevin PF00957.21 OEU17684.1 - 5.4 6.9 9.2 0.26 11.1 1.1 2.8 3 0 0 3 3 3 0 Synaptobrevin STIL_N PF15253.6 OEU17685.1 - 0.034 13.1 0.1 0.055 12.4 0.1 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Sld7_N PF18636.1 OEU17685.1 - 0.067 13.5 2.5 0.56 10.6 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain GREB1 PF15782.5 OEU17686.1 - 0.019 12.2 5.6 0.026 11.7 5.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TSC22 PF01166.18 OEU17686.1 - 0.44 10.9 6.5 0.5 10.7 0.4 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF2681 PF10883.8 OEU17686.1 - 0.9 10.0 10.6 4.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Thymidylate_kin PF02223.17 OEU17689.1 - 8.6e-40 136.4 0.0 1e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase DUF4795 PF16043.5 OEU17689.1 - 0.025 14.2 1.7 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) AAA_14 PF13173.6 OEU17689.1 - 0.046 13.8 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OEU17689.1 - 0.051 14.1 0.1 0.13 12.8 0.0 1.8 1 1 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 OEU17690.1 - 4.3e-48 164.0 2.9 6.1e-48 163.5 2.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU17690.1 - 3.4e-27 94.9 0.3 5.4e-25 87.8 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU17690.1 - 9.3e-16 58.2 11.3 2.1e-15 57.0 0.2 3.4 3 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU17690.1 - 8e-09 35.1 3.8 2.5e-06 26.9 1.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OEU17690.1 - 1.8e-07 30.7 4.3 0.00074 18.9 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OEU17690.1 - 5.4e-05 23.2 4.1 0.00025 21.0 0.3 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 OEU17690.1 - 8.1e-05 22.8 7.9 0.056 13.7 1.8 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 OEU17690.1 - 0.00012 21.5 0.1 0.00045 19.6 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 OEU17690.1 - 0.0028 17.1 2.2 0.0041 16.5 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 OEU17690.1 - 0.0047 17.1 0.3 0.013 15.6 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.6 OEU17690.1 - 0.0074 15.6 0.1 0.0074 15.6 0.1 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU17690.1 - 0.042 12.5 10.7 0.54 8.9 3.6 2.9 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.20 OEU17690.1 - 0.044 13.8 0.2 0.55 10.3 0.1 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 OEU17690.1 - 0.056 13.9 0.1 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain K_oxygenase PF13434.6 OEU17690.1 - 0.06 12.5 0.9 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_transf_4 PF13439.6 OEU17690.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 UDPG_MGDP_dh_N PF03721.14 OEU17690.1 - 0.1 12.2 6.4 0.36 10.4 0.3 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 OEU17690.1 - 0.16 12.6 0.5 0.55 10.9 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 OEU17690.1 - 0.17 11.7 1.0 13 5.6 0.1 2.2 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DAO PF01266.24 OEU17690.1 - 1.2 8.7 12.0 1 8.9 0.4 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OEU17690.1 - 1.9 7.5 8.2 2.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein MOSC PF03473.17 OEU17692.1 - 9.9e-19 67.7 0.0 2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OEU17692.1 - 1.1e-18 67.3 0.0 2.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OEU17692.1 - 3.6e-16 59.1 0.0 5.7e-13 48.6 0.0 3.1 4 0 0 4 4 4 2 Aminotransferase class-V Zip PF02535.22 OEU17692.1 - 0.00039 19.8 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter TraE PF05309.11 OEU17692.1 - 0.037 13.4 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 TraE protein TRP PF06011.12 OEU17692.1 - 0.043 12.5 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel NicO PF03824.16 OEU17692.1 - 0.11 11.8 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein RSB_motif PF16294.5 OEU17692.1 - 0.42 10.9 4.8 3 8.2 0.0 3.2 3 0 0 3 3 3 0 RNSP1-SAP18 binding (RSB) motif PHINT_rpt PF14882.6 OEU17693.1 - 1e-08 35.3 1.4 1.3e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Phage-integrase repeat unit Ferredoxin_N PF16947.5 OEU17693.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Fcf2 PF08698.11 OEU17695.1 - 1.1e-28 99.5 0.1 1.1e-28 99.5 0.1 1.6 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Peptidase_S24 PF00717.23 OEU17696.1 - 2.2e-12 46.7 0.0 1.7e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 OEU17696.1 - 2.8e-08 33.6 0.0 9.7e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Arginosuc_synth PF00764.19 OEU17697.1 - 2.7e-148 494.4 0.0 3.1e-148 494.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Ish1 PF10281.9 OEU17697.1 - 0.036 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein QueC PF06508.13 OEU17697.1 - 0.053 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC MTP18 PF10558.9 OEU17698.1 - 2.4e-20 73.2 3.9 2.6e-18 66.6 3.9 2.1 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2689 PF10894.8 OEU17698.1 - 0.078 12.8 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) ABC1 PF03109.16 OEU17699.1 - 1.7e-28 99.2 0.0 3.5e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU17699.1 - 1.4e-05 25.2 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU17699.1 - 0.00013 21.5 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17699.1 - 0.12 11.7 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase FlpD PF02662.16 OEU17700.1 - 0.13 12.3 0.9 0.2 11.6 0.9 1.2 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit DNA_ligase_A_M PF01068.21 OEU17702.1 - 3.6e-50 170.4 0.1 2.1e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OEU17702.1 - 4.4e-32 111.8 0.0 1e-31 110.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OEU17702.1 - 2e-24 86.1 0.0 5.4e-24 84.7 0.0 1.8 2 0 0 2 2 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OEU17702.1 - 2.6e-07 31.1 0.3 4.2e-07 30.4 0.3 1.4 1 0 0 1 1 1 1 RNA ligase TrmB PF01978.19 OEU17702.1 - 0.0088 15.9 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_ner PF04546.13 OEU17702.1 - 0.026 14.4 4.8 0.47 10.3 0.5 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_ligase_OB_2 PF14743.6 OEU17702.1 - 0.062 13.3 0.2 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain FAM176 PF14851.6 OEU17702.1 - 0.58 9.8 5.8 2.6 7.7 0.8 2.4 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 OEU17702.1 - 0.87 9.6 8.8 5 7.1 0.4 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 OEU17702.1 - 1.3 9.4 24.9 0.13 12.7 1.7 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 OEU17702.1 - 1.6 9.4 12.7 2 9.1 5.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFB6 PF17110.5 OEU17702.1 - 4.1 7.1 5.6 4.6 7.0 1.0 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH ApbA PF02558.16 OEU17703.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA LolB PF03550.14 OEU17703.1 - 0.033 14.2 0.0 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Outer membrane lipoprotein LolB AMP-binding PF00501.28 OEU17704.1 - 3.3e-86 289.5 0.0 4.3e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OEU17704.1 - 3.2e-13 50.4 0.1 8.5e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 OEU17704.1 - 0.0027 16.6 0.0 0.043 12.7 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter GFO_IDH_MocA PF01408.22 OEU17705.1 - 5.9e-27 94.9 0.5 1e-26 94.1 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OEU17705.1 - 6.1e-08 32.7 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 OEU17705.1 - 8.1e-05 22.9 0.2 0.00022 21.5 0.2 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 OEU17705.1 - 0.0025 18.4 0.1 0.0053 17.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 OEU17705.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain HYR PF02494.16 OEU17705.1 - 0.084 13.2 0.0 3.7 7.9 0.0 2.6 2 0 0 2 2 2 0 HYR domain 2-Hacid_dh_C PF02826.19 OEU17705.1 - 0.093 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3484 PF11983.8 OEU17705.1 - 0.095 13.8 0.2 0.44 11.7 0.0 2.2 2 1 1 3 3 3 0 Membrane-attachment and polymerisation-promoting switch NeuB PF03102.14 OEU17705.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NeuB family Gp_dh_N PF00044.24 OEU17705.1 - 0.17 12.2 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Solute_trans_a PF03619.16 OEU17706.1 - 2.1e-50 171.7 6.6 2.5e-50 171.5 6.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CBS PF00571.28 OEU17707.1 - 5.9e-20 71.5 0.4 1.7e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 CBS domain DUF1827 PF08860.10 OEU17707.1 - 0.036 14.3 0.2 0.063 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) Fer2_4 PF13510.6 OEU17707.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Pex26 PF07163.12 OEU17708.1 - 0.51 9.6 2.5 0.93 8.7 2.5 1.3 1 0 0 1 1 1 0 Pex26 protein Na_H_Exchanger PF00999.21 OEU17709.1 - 3.7e-10 39.1 0.3 5.1e-10 38.7 0.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FA_desaturase PF00487.24 OEU17710.1 - 1.1e-12 48.4 16.6 2.2e-12 47.4 16.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DNA_pol_phi PF04931.13 OEU17712.1 - 1.3 7.0 5.8 2.1 6.4 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RWD PF05773.22 OEU17713.1 - 3.5e-14 53.1 0.4 8.6e-14 51.8 0.1 1.8 2 0 0 2 2 2 1 RWD domain SRP54 PF00448.22 OEU17714.1 - 5.5e-77 257.8 0.1 1.1e-76 256.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OEU17714.1 - 1.4e-28 99.4 0.3 1.4e-28 99.4 0.3 3.1 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 OEU17714.1 - 5.4e-12 45.8 7.3 1.8e-11 44.1 7.3 2.0 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 OEU17714.1 - 1.3e-07 31.1 0.1 8.3e-07 28.5 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_16 PF13191.6 OEU17714.1 - 8.1e-06 26.3 0.0 2.3e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 OEU17714.1 - 1.7e-05 24.5 0.2 0.00016 21.3 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OEU17714.1 - 2.6e-05 24.0 0.1 9.8e-05 22.1 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU17714.1 - 9.3e-05 22.6 0.1 0.00028 21.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.20 OEU17714.1 - 0.0027 17.6 0.4 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase MeaB PF03308.16 OEU17714.1 - 0.0036 16.3 4.5 0.032 13.2 0.0 3.1 3 1 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OEU17714.1 - 0.0049 16.9 1.3 0.014 15.4 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.15 OEU17714.1 - 0.0052 16.8 1.1 0.095 12.7 1.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OEU17714.1 - 0.0062 16.9 0.8 0.013 15.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 OEU17714.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 OEU17714.1 - 0.016 15.1 0.1 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 OEU17714.1 - 0.017 15.4 0.1 0.066 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OEU17714.1 - 0.019 15.4 0.1 0.019 15.4 0.1 3.0 3 1 0 3 3 2 0 AAA domain AAA_24 PF13479.6 OEU17714.1 - 0.033 13.9 0.4 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OEU17714.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OEU17714.1 - 0.043 13.3 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF16 PF01519.16 OEU17714.1 - 0.044 14.3 5.0 2.1 8.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA PF00004.29 OEU17714.1 - 0.072 13.5 2.3 0.22 12.0 0.0 3.0 3 2 1 4 4 2 0 ATPase family associated with various cellular activities (AAA) RXT2_N PF08595.11 OEU17714.1 - 0.092 12.8 4.7 0.18 11.8 4.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4710 PF15828.5 OEU17714.1 - 0.13 12.4 0.3 0.45 10.7 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF4304 PF14137.6 OEU17714.1 - 0.15 12.2 0.3 0.43 10.7 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4304) ArsA_ATPase PF02374.15 OEU17714.1 - 2.3 7.3 7.2 9.3 5.3 0.1 3.6 3 1 0 3 3 3 0 Anion-transporting ATPase CPBP PF02517.16 OEU17715.1 - 0.00022 21.5 0.0 0.0025 18.2 0.0 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Pox_Ag35 PF03286.14 OEU17715.1 - 9.6 5.9 9.1 1.4 8.7 3.0 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Molybdop_Fe4S4 PF04879.16 OEU17718.1 - 0.074 13.0 0.8 0.13 12.3 0.8 1.4 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain zf-GRF PF06839.12 OEU17718.1 - 0.53 10.4 7.3 0.21 11.7 4.2 1.9 2 0 0 2 2 2 0 GRF zinc finger CorA PF01544.18 OEU17719.1 - 1.4e-30 106.7 0.1 1.2e-24 87.1 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_1 PF00036.32 OEU17719.1 - 2.5e-11 42.3 0.2 5.1e-05 22.5 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU17719.1 - 4e-10 38.8 0.3 2.7e-05 23.8 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU17719.1 - 2.6e-09 37.4 0.7 8.6e-09 35.7 0.7 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU17719.1 - 1.7e-07 30.4 4.3 0.0021 17.5 0.1 3.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OEU17719.1 - 3.8e-07 29.9 0.5 0.0072 16.2 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 OEU17719.1 - 0.06 13.3 0.3 2.6 8.0 0.1 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF4453 PF14627.6 OEU17720.1 - 0.0024 18.0 0.0 0.0041 17.2 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4453) DUF3106 PF11304.8 OEU17720.1 - 0.044 14.3 1.7 31 5.1 0.2 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) MatE PF01554.18 OEU17721.1 - 5.9e-25 87.8 27.6 3.4e-13 49.6 12.2 2.6 2 0 0 2 2 2 2 MatE Peptidase_M3 PF01432.20 OEU17723.1 - 1.5e-112 377.2 6.8 2e-112 376.8 6.8 1.2 1 0 0 1 1 1 1 Peptidase family M3 Reprolysin_5 PF13688.6 OEU17723.1 - 2.6 8.2 5.1 0.7 10.0 0.1 2.5 3 0 0 3 3 3 0 Metallo-peptidase family M12 Methyltransf_32 PF13679.6 OEU17724.1 - 3.8e-16 59.5 0.1 5.8e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU17724.1 - 9.7e-09 35.8 0.0 2.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU17724.1 - 4.4e-08 33.1 0.1 6.6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU17724.1 - 4.5e-07 29.6 0.1 9.5e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OEU17724.1 - 6e-05 22.5 0.1 0.00013 21.4 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OEU17724.1 - 0.00012 22.6 0.0 0.00025 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 OEU17724.1 - 0.00087 18.9 4.3 0.038 13.5 4.3 2.8 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_18 PF12847.7 OEU17724.1 - 0.0027 17.7 0.2 0.0056 16.6 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 OEU17724.1 - 0.0046 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 OEU17724.1 - 0.012 16.3 0.1 0.025 15.3 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OEU17724.1 - 0.044 13.2 0.5 0.069 12.5 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OEU17724.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OEU17724.1 - 0.12 12.4 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OEU17724.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Brix PF04427.18 OEU17725.1 - 9.6e-32 110.7 0.2 1.3e-31 110.2 0.2 1.2 1 0 0 1 1 1 1 Brix domain PUB PF09409.10 OEU17726.1 - 1.4e-14 53.8 0.1 3.8e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 PUB domain Thioredoxin PF00085.20 OEU17726.1 - 7.9e-13 48.3 0.2 2.2e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU17726.1 - 0.00041 20.8 1.2 0.002 18.5 0.2 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU17726.1 - 0.0015 18.8 0.1 0.02 15.2 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like zf-C2H2 PF00096.26 OEU17726.1 - 0.004 17.5 0.1 0.0087 16.5 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type Redoxin PF08534.10 OEU17726.1 - 0.018 14.8 0.5 0.062 13.0 0.2 2.1 2 0 0 2 2 2 0 Redoxin Thioredoxin_9 PF14595.6 OEU17726.1 - 0.035 13.9 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin NTS_2 PF15448.6 OEU17726.1 - 9.3 6.7 7.3 61 4.1 0.7 3.9 4 0 0 4 4 4 0 N-terminal segments of P. falciparum erythrocyte membrane protein RCR PF12273.8 OEU17727.1 - 0.83 10.3 10.0 0.5 11.0 6.6 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red zf-CCCH PF00642.24 OEU17728.1 - 1e-15 57.2 14.8 1.9e-08 34.0 2.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OEU17728.1 - 7.2e-14 51.2 20.3 2e-07 30.7 5.9 2.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OEU17728.1 - 1.7e-09 37.4 20.6 3.2e-06 27.0 5.5 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 OEU17728.1 - 2.1e-05 24.8 17.6 0.014 15.9 4.1 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger DUF2931 PF11153.8 OEU17728.1 - 0.0032 17.2 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2931) Torus PF16131.5 OEU17728.1 - 0.0049 17.5 8.7 0.12 13.1 0.6 3.1 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 OEU17728.1 - 0.1 12.8 6.4 0.54 10.5 6.4 2.1 1 1 0 1 1 1 0 Zinc-finger containing family Spt5_N PF11942.8 OEU17728.1 - 0.24 12.4 11.0 1.8 9.6 4.6 2.8 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-CCHH PF10283.9 OEU17728.1 - 1.7 8.7 4.5 10 6.2 0.2 2.6 2 0 0 2 2 2 0 PBZ domain Mucin PF01456.17 OEU17728.1 - 6.4 6.8 25.7 9.9 6.2 3.1 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein PAS PF00989.25 OEU17729.1 - 0.00034 20.6 0.0 0.00084 19.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OEU17729.1 - 0.004 17.4 0.0 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain Pox_LP_H2 PF03356.15 OEU17729.1 - 0.052 13.4 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Viral late protein H2 Rubredoxin_C PF18267.1 OEU17729.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain WD40 PF00400.32 OEU17730.1 - 5.2e-10 39.8 4.2 0.0093 16.8 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU17730.1 - 2.7e-05 24.4 0.1 0.09 13.1 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU17730.1 - 0.0037 16.3 0.0 0.0074 15.3 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_C PF00034.21 OEU17731.1 - 5.7e-14 53.0 0.1 8e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OEU17731.1 - 9.6e-08 32.2 1.7 5.6e-07 29.8 1.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OEU17731.1 - 0.004 16.9 0.5 0.042 13.6 0.2 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 OEU17731.1 - 0.034 14.5 1.1 3.7 7.9 0.3 2.1 2 0 0 2 2 2 0 Cytochrome P460 Haem_bd PF14376.6 OEU17731.1 - 0.13 12.3 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Haem-binding domain DUF3584 PF12128.8 OEU17732.1 - 0.0032 15.1 0.7 0.0034 15.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) LUC7 PF03194.15 OEU17732.1 - 0.0054 16.4 1.0 0.0059 16.3 1.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus ATP-synt_D PF01813.17 OEU17732.1 - 0.009 15.9 3.8 0.012 15.5 3.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Methyltransf_5 PF01795.19 OEU17732.1 - 0.021 14.3 0.1 0.023 14.2 0.1 1.0 1 0 0 1 1 1 0 MraW methylase family PCRF PF03462.18 OEU17732.1 - 0.028 14.3 2.0 0.034 14.0 2.0 1.1 1 0 0 1 1 1 0 PCRF domain L31 PF09784.9 OEU17732.1 - 0.031 14.7 0.9 0.04 14.3 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Shugoshin_N PF07558.11 OEU17732.1 - 0.037 13.9 0.9 0.037 13.9 0.9 1.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region EPO_TPO PF00758.18 OEU17732.1 - 0.041 13.9 0.3 0.05 13.6 0.3 1.1 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Prominin PF05478.11 OEU17732.1 - 0.047 11.7 0.8 0.053 11.5 0.8 1.0 1 0 0 1 1 1 0 Prominin Prefoldin_2 PF01920.20 OEU17732.1 - 0.072 13.0 9.4 10 6.1 9.2 2.1 1 1 0 1 1 1 0 Prefoldin subunit SlyX PF04102.12 OEU17732.1 - 0.099 13.3 3.0 7.5 7.3 0.2 2.1 1 1 1 2 2 2 0 SlyX AAA_23 PF13476.6 OEU17732.1 - 0.71 10.3 6.5 0.83 10.1 6.5 1.0 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.11 OEU17732.1 - 0.88 9.8 7.7 1.4 9.2 0.6 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Spc29 PF17082.5 OEU17732.1 - 1 9.2 5.5 0.61 9.9 1.0 1.9 1 1 1 2 2 2 0 Spindle Pole Component 29 YabA PF06156.13 OEU17732.1 - 1.5 9.5 5.5 1 10.1 1.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 OEU17732.1 - 1.6 8.8 6.9 4.1 7.6 1.1 2.1 1 1 1 2 2 2 0 Swi5 DivIC PF04977.15 OEU17732.1 - 3.8 7.3 6.9 38 4.1 6.9 2.0 1 1 0 1 1 1 0 Septum formation initiator TMEM144 PF07857.12 OEU17733.1 - 1.3e-17 63.8 20.8 1.5e-16 60.3 20.8 2.6 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 OEU17733.1 - 5.4e-07 29.2 21.4 1.8e-05 24.2 3.0 3.2 2 2 1 3 3 3 2 Sugar transport protein Ureide_permease PF07168.11 OEU17733.1 - 0.06 12.1 8.8 0.84 8.3 2.0 2.2 2 0 0 2 2 2 0 Ureide permease DSRB PF10781.9 OEU17733.1 - 0.86 9.3 3.9 4.1 7.1 1.3 2.5 2 1 0 2 2 2 0 Dextransucrase DSRB Cytochrom_B561 PF03188.16 OEU17734.1 - 2.1e-15 57.1 6.5 2.1e-15 57.1 6.5 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF998 PF06197.13 OEU17734.1 - 0.00061 19.4 0.4 0.00099 18.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) CrgA PF06781.12 OEU17735.1 - 0.002 18.1 0.8 0.0033 17.4 0.1 1.7 2 0 0 2 2 2 1 Cell division protein CrgA PEN-2 PF10251.9 OEU17735.1 - 0.051 14.0 0.3 0.13 12.7 0.3 1.6 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Glyco_transf_8 PF01501.20 OEU17736.1 - 0.0018 17.9 0.3 0.0031 17.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 RSS_P20 PF11757.8 OEU17736.1 - 0.0027 18.1 0.9 0.0052 17.2 0.1 1.8 2 0 0 2 2 2 1 Suppressor of RNA silencing P21-like N-terminal domain DUF2441 PF10386.9 OEU17736.1 - 0.04 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) DEDD_Tnp_IS110 PF01548.17 OEU17736.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Transposase RNA_pol_A_bac PF01000.26 OEU17737.1 - 1.2e-27 96.5 0.0 2e-26 92.5 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OEU17737.1 - 8.6e-23 79.6 0.0 2.2e-22 78.3 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CobN-Mg_chel PF02514.16 OEU17740.1 - 1e-278 927.5 0.0 8.7e-277 921.1 0.0 2.0 1 1 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 OEU17740.1 - 2e-30 106.0 0.0 3.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Hexapep PF00132.24 OEU17741.1 - 1.3e-07 31.0 5.0 0.0011 18.6 0.2 2.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OEU17741.1 - 8e-06 26.3 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 OEU17741.1 - 1.8e-05 24.4 0.0 6.5e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 OEU17741.1 - 0.011 14.0 0.3 0.017 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 OEU17741.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Rieske PF00355.26 OEU17742.1 - 2.2e-12 46.7 0.0 3.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 OEU17742.1 - 3.2e-10 39.9 0.2 3.2e-10 39.9 0.2 1.8 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit DegV PF02645.16 OEU17744.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 HA PF03457.14 OEU17745.1 - 1.6e-27 95.6 7.0 5.4e-14 52.3 0.7 3.0 2 0 0 2 2 2 2 Helicase associated domain Myc_N PF01056.18 OEU17745.1 - 0.015 15.2 0.5 0.015 15.2 0.5 2.7 3 0 0 3 3 3 0 Myc amino-terminal region Nop14 PF04147.12 OEU17748.1 - 2.1 6.4 33.6 2.9 6.0 33.6 1.2 1 0 0 1 1 1 0 Nop14-like family Hamartin PF04388.12 OEU17748.1 - 3.2 6.3 18.6 4.3 5.9 18.6 1.2 1 0 0 1 1 1 0 Hamartin protein PalH PF08733.10 OEU17748.1 - 3.3 6.6 5.5 0.3 10.1 0.2 1.6 1 1 0 2 2 2 0 PalH/RIM21 DIM1 PF02966.16 OEU17749.1 - 1.1e-64 216.2 0.8 1.2e-64 216.0 0.8 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 GlcNAc-1_reg PF18440.1 OEU17749.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF3192 PF11399.8 OEU17749.1 - 0.093 12.7 0.2 0.14 12.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) Ank_5 PF13857.6 OEU17751.1 - 0.0084 16.4 0.1 0.031 14.6 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU17751.1 - 0.062 13.9 0.1 0.32 11.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat UxuA PF03786.13 OEU17751.1 - 0.18 10.6 0.0 0.49 9.2 0.0 1.6 2 0 0 2 2 2 0 D-mannonate dehydratase (UxuA) Sld5 PF05916.11 OEU17752.1 - 3.5e-16 59.6 0.0 5.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein SR-25 PF10500.9 OEU17752.1 - 9.5 5.8 9.8 1 8.9 4.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lactamase_B_2 PF12706.7 OEU17753.1 - 0.032 13.8 0.1 0.077 12.5 0.1 1.6 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF3192 PF11399.8 OEU17753.1 - 0.052 13.5 3.1 0.059 13.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) zf-RING_2 PF13639.6 OEU17754.1 - 8e-08 32.5 5.4 1.2e-07 32.0 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain Ank_5 PF13857.6 OEU17754.1 - 2.7e-06 27.5 0.0 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-RING_5 PF14634.6 OEU17754.1 - 4.1e-06 26.7 6.6 5.7e-06 26.2 6.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OEU17754.1 - 5.2e-05 23.4 4.2 0.00012 22.3 4.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU17754.1 - 0.00027 20.8 7.2 0.00048 19.9 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU17754.1 - 0.00046 20.1 0.9 0.00079 19.4 0.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU17754.1 - 0.0015 18.5 2.4 0.0031 17.5 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OEU17754.1 - 0.0017 18.0 4.7 0.0032 17.2 4.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU17754.1 - 0.015 15.2 8.6 0.099 12.5 9.1 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OEU17754.1 - 0.016 15.1 6.3 0.024 14.5 5.9 1.5 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OEU17754.1 - 0.029 14.5 5.7 0.1 12.8 5.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 OEU17754.1 - 0.091 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 OEU17754.1 - 0.14 12.1 5.6 0.24 11.3 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU17754.1 - 0.22 11.4 5.9 0.6 10.0 5.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 OEU17754.1 - 0.25 11.4 3.6 0.52 10.4 3.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 OEU17754.1 - 0.25 11.3 3.7 8.5 6.4 1.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 OEU17754.1 - 0.33 11.2 4.7 0.68 10.2 4.7 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 OEU17754.1 - 0.4 11.0 4.5 0.87 10.0 3.9 1.8 1 1 1 2 2 2 0 RING-like domain Zn_ribbon_17 PF17120.5 OEU17754.1 - 0.51 10.0 5.7 0.89 9.2 4.9 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OEU17754.1 - 0.56 10.0 5.1 1.1 9.0 5.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OEU17754.1 - 1.4 9.3 6.1 0.78 10.1 1.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD_2 PF13831.6 OEU17754.1 - 4.3 7.0 6.0 4 7.1 2.8 2.2 2 0 0 2 2 2 0 PHD-finger Shisa PF13908.6 OEU17755.1 - 0.012 15.9 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ATPase PF06745.13 OEU17755.1 - 0.02 14.2 0.1 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 KaiC Herpes_gE PF02480.16 OEU17755.1 - 0.024 13.4 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4834 PF16118.5 OEU17755.1 - 0.054 14.5 1.4 0.057 14.4 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF4446 PF14584.6 OEU17755.1 - 0.066 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3169 PF11368.8 OEU17755.1 - 0.076 12.5 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Vpu PF00558.19 OEU17755.1 - 0.08 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Vpu protein COX16 PF14138.6 OEU17755.1 - 0.12 12.9 0.2 0.41 11.2 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 EphA2_TM PF14575.6 OEU17755.1 - 0.14 13.1 0.2 0.22 12.4 0.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM108 PF15759.5 OEU17755.1 - 0.17 10.9 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 TMEM108 family FAM176 PF14851.6 OEU17755.1 - 0.38 10.4 2.0 0.34 10.6 1.4 1.4 1 1 0 1 1 1 0 FAM176 family GFA PF04828.14 OEU17757.1 - 2.6e-06 27.7 0.2 2.6e-06 27.7 0.2 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme LHH PF14411.6 OEU17757.1 - 0.14 12.3 0.4 0.29 11.3 0.4 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH HA PF03457.14 OEU17758.1 - 1.7e-22 79.5 1.4 3.7e-12 46.4 0.6 2.1 2 0 0 2 2 2 2 Helicase associated domain AAA PF00004.29 OEU17759.1 - 1.4e-32 112.9 0.0 2.4e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU17759.1 - 8.8e-07 29.0 0.0 3e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OEU17759.1 - 7.9e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OEU17759.1 - 1.1e-05 25.8 0.2 0.034 14.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 OEU17759.1 - 1.7e-05 25.2 0.0 8.9e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OEU17759.1 - 0.00023 21.3 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OEU17759.1 - 0.0017 18.3 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.13 OEU17759.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 OEU17759.1 - 0.0022 17.4 0.2 0.011 15.1 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OEU17759.1 - 0.0025 17.5 0.0 0.0092 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU17759.1 - 0.0037 17.8 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OEU17759.1 - 0.0051 16.0 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 OEU17759.1 - 0.014 15.0 0.3 0.45 10.1 0.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OEU17759.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OEU17759.1 - 0.041 14.0 0.0 0.07 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU17759.1 - 0.045 14.2 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 OEU17759.1 - 0.046 13.5 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_13 PF13166.6 OEU17759.1 - 0.061 12.0 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OEU17759.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC1 PF03109.16 OEU17760.1 - 1.4e-27 96.2 0.0 2.9e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU17760.1 - 0.00014 21.9 0.1 0.04 13.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DNA_pol_B PF00136.21 OEU17762.1 - 5.2e-117 391.4 0.1 7.1e-117 390.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OEU17762.1 - 1.7e-34 119.2 2.9 3.5e-34 118.2 2.9 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OEU17762.1 - 5.7e-28 98.0 0.0 1.5e-27 96.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 OEU17762.1 - 0.0029 16.3 0.1 0.0044 15.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) PP2 PF14299.6 OEU17762.1 - 0.027 14.5 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Phloem protein 2 Exonuc_VII_S PF02609.16 OEU17762.1 - 0.042 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit DNA_pol_B_2 PF03175.13 OEU17762.1 - 0.062 12.2 0.3 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DUF4030 PF13222.6 OEU17762.1 - 0.073 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) DNA_pol_B_exo2 PF10108.9 OEU17762.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Oxidored_FMN PF00724.20 OEU17762.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Str_synth PF03088.16 OEU17763.1 - 1.9e-16 59.9 0.0 4.6e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 OEU17763.1 - 3.9e-08 33.2 0.1 7.6e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OEU17763.1 - 0.064 13.5 0.0 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Arylesterase PQQ PF01011.21 OEU17763.1 - 0.12 12.3 0.0 0.6 10.1 0.0 2.2 1 0 0 1 1 1 0 PQQ enzyme repeat Reg_prop PF07494.11 OEU17763.1 - 0.43 11.0 2.4 2.2e+02 2.7 0.0 4.0 3 0 0 3 3 3 0 Two component regulator propeller bZIP_1 PF00170.21 OEU17764.1 - 0.0068 16.5 4.7 0.023 14.8 4.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU17764.1 - 0.023 14.8 8.5 0.064 13.4 8.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper K_channel_TID PF07941.11 OEU17764.1 - 0.11 12.9 0.2 0.11 12.9 0.2 4.3 4 2 1 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain HA2 PF04408.23 OEU17765.1 - 6.8e-18 64.9 0.0 6.8e-18 64.9 0.0 5.1 4 1 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OEU17765.1 - 1.7e-11 44.3 0.4 5.3e-11 42.7 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OEU17765.1 - 0.0019 18.5 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU17765.1 - 0.0095 16.3 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 OEU17765.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 OEU17765.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 OEU17765.1 - 0.066 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 OEU17765.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 OEU17765.1 - 0.094 12.5 0.2 0.61 9.8 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 OEU17765.1 - 0.13 12.8 0.0 0.13 12.8 0.0 2.9 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.12 OEU17765.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 OEU17766.1 - 2.2e-15 56.8 0.3 2.6e-15 56.7 0.3 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OEU17766.1 - 0.00019 21.5 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OEU17766.1 - 0.0018 18.6 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU17766.1 - 0.0087 15.8 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OEU17766.1 - 0.057 12.9 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 OEU17766.1 - 0.058 12.5 0.1 0.058 12.5 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein T4SS-DNA_transf PF02534.14 OEU17766.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Synaphin PF05835.12 OEU17767.1 - 0.013 15.8 12.4 0.027 14.8 12.4 1.5 1 0 0 1 1 1 0 Synaphin protein SOBP PF15279.6 OEU17767.1 - 0.19 12.3 13.0 0.31 11.6 13.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CCSAP PF15748.5 OEU17767.1 - 4.7 7.3 25.0 7.3 6.7 25.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ABC_tran PF00005.27 OEU17768.1 - 1.1e-18 68.1 0.0 1.4e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU17768.1 - 7.6e-06 25.5 0.1 6.9e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU17768.1 - 8.1e-05 22.6 0.8 0.067 13.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OEU17768.1 - 0.02 15.1 0.5 0.25 11.6 0.5 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 OEU17768.1 - 0.024 15.0 0.2 0.033 14.6 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OEU17768.1 - 0.037 14.4 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OEU17768.1 - 0.038 13.9 0.1 0.08 12.9 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 OEU17768.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OEU17768.1 - 0.044 14.1 0.4 0.1 12.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OEU17768.1 - 0.057 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Adeno_IVa2 PF02456.15 OEU17768.1 - 0.069 11.9 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 OEU17768.1 - 0.074 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OEU17768.1 - 0.09 12.8 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OEU17768.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 OEU17768.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PRK PF00485.18 OEU17768.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 OEU17768.1 - 0.15 11.9 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 OEU17768.1 - 0.2 12.0 0.0 1.2 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain UPF0014 PF03649.13 OEU17769.1 - 1.1e-54 185.4 12.2 1.3e-54 185.1 12.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) HPP PF04982.13 OEU17769.1 - 3.1 8.0 8.4 0.81 9.9 3.1 2.3 1 1 1 2 2 2 0 HPP family Lipocalin_2 PF08212.12 OEU17770.1 - 2.4e-23 82.7 0.1 3.3e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Lipocalin-like domain WD40 PF00400.32 OEU17771.1 - 7.9e-10 39.2 0.6 0.002 18.9 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 OEU17771.1 - 1.4e-08 34.2 8.9 3.8e-08 32.8 8.9 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DZR PF12773.7 OEU17771.1 - 0.097 12.7 10.3 3.2 7.9 10.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_16 PF17034.5 OEU17771.1 - 0.56 10.4 12.6 46 4.2 12.6 3.3 1 1 0 1 1 1 0 Zinc-ribbon like family MoCF_biosynth PF00994.24 OEU17772.1 - 3.4e-24 85.1 0.1 8.9e-24 83.8 0.1 1.6 1 1 0 1 1 1 1 Probable molybdopterin binding domain DUF3052 PF11253.8 OEU17772.1 - 0.12 12.3 1.0 0.2 11.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Lact-deh-memb PF09330.11 OEU17774.1 - 2.7e-58 197.6 0.0 6.6e-58 196.3 0.0 1.6 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding FAD_binding_4 PF01565.23 OEU17774.1 - 7.5e-10 38.7 0.0 2.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 OEU17774.1 - 0.084 12.5 3.3 0.58 9.7 3.3 2.5 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Metallophos PF00149.28 OEU17778.1 - 7.1e-07 29.9 5.6 3.7e-06 27.6 5.6 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NUDIX PF00293.28 OEU17778.1 - 0.0069 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.21 OEU17779.1 - 4.6e-33 114.9 0.5 1e-32 113.8 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 OEU17779.1 - 1.8e-23 82.4 2.5 7.9e-23 80.4 2.5 2.0 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 OEU17779.1 - 8.8e-08 32.0 0.1 1.7e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 TRAM domain PIG-U PF06728.13 OEU17780.1 - 0.085 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U MDD_C PF18376.1 OEU17781.1 - 2.4e-72 242.6 0.5 3.4e-72 242.1 0.5 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OEU17781.1 - 3.9e-07 30.2 3.8 3.9e-07 30.2 3.8 3.0 3 0 0 3 3 3 1 GHMP kinases N terminal domain Peptidase_C69 PF03577.15 OEU17782.1 - 6.4e-42 143.9 2.3 1.2e-39 136.4 2.3 2.9 1 1 0 1 1 1 1 Peptidase family C69 Lipase_GDSL_2 PF13472.6 OEU17783.1 - 0.023 15.1 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU17783.1 - 0.041 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase 2OG-FeII_Oxy_3 PF13640.6 OEU17784.1 - 7e-08 33.3 0.0 1.3e-07 32.4 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU17784.1 - 0.034 14.8 0.0 0.054 14.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily O-FucT PF10250.9 OEU17785.1 - 0.00099 18.9 0.8 0.068 12.9 0.1 2.3 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase LrgB PF04172.16 OEU17786.1 - 4e-36 124.5 17.4 4e-36 124.5 17.4 2.5 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 OEU17786.1 - 0.01 15.8 0.8 0.01 15.8 0.8 3.9 4 0 0 4 4 4 0 LrgA family TLC PF03219.14 OEU17787.1 - 1.9e-12 46.7 15.9 1.4e-07 30.6 1.3 4.5 4 1 0 4 4 4 2 TLC ATP/ADP transporter SARAF PF06682.12 OEU17787.1 - 0.2 11.3 7.9 3.6 7.2 0.7 3.4 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis FAM176 PF14851.6 OEU17787.1 - 0.24 11.1 10.2 25 4.5 3.7 4.4 4 0 0 4 4 4 0 FAM176 family ETRAMP PF09716.10 OEU17787.1 - 4.3 7.5 0.0 4.3 7.5 0.0 4.0 5 0 0 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) DUF3899 PF13038.6 OEU17787.1 - 7.5 7.1 9.3 12 6.4 0.3 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3899) Mgr1 PF08602.10 OEU17788.1 - 0.002 17.0 4.4 0.0032 16.4 4.4 1.2 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit SUIM_assoc PF16619.5 OEU17788.1 - 0.0073 16.4 0.7 0.0073 16.4 0.7 3.2 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 OEU17788.1 - 0.044 13.8 12.5 0.056 13.4 12.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF853 PF05872.12 OEU17788.1 - 0.077 11.6 3.0 0.094 11.3 3.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Kei1 PF08552.11 OEU17788.1 - 0.2 11.5 2.2 0.37 10.7 2.2 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 YABBY PF04690.13 OEU17788.1 - 0.51 10.9 7.1 0.99 10.0 7.1 1.5 1 0 0 1 1 1 0 YABBY protein Hydin_ADK PF17213.3 OEU17788.1 - 1.1 9.5 9.3 0.098 12.9 4.4 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Coilin_N PF15862.5 OEU17788.1 - 1.3 8.9 10.2 2.2 8.1 10.2 1.4 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 OEU17788.1 - 1.7 7.4 9.4 2.3 6.9 9.4 1.2 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 OEU17788.1 - 2.1 7.3 4.4 3.5 6.6 4.4 1.3 1 0 0 1 1 1 0 CLN3 protein DUF3381 PF11861.8 OEU17788.1 - 2.1 8.1 12.5 3.1 7.6 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4407 PF14362.6 OEU17788.1 - 5 6.4 9.6 7.6 5.8 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRAL_TRIO_N PF03765.15 OEU17789.1 - 0.0083 16.3 2.3 0.013 15.6 0.7 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Glycoprot_B_PH2 PF17417.2 OEU17790.1 - 5.9 7.3 7.6 1.3 9.4 1.9 3.0 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain H_PPase PF03030.16 OEU17793.1 - 4.3e-239 795.5 33.8 4.9e-239 795.3 33.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase LrgB PF04172.16 OEU17794.1 - 2.1e-40 138.5 13.4 2.1e-40 138.5 13.4 2.6 3 0 0 3 3 3 1 LrgB-like family LrgA PF03788.14 OEU17794.1 - 0.00048 20.0 5.9 0.028 14.3 2.6 3.0 2 0 0 2 2 2 2 LrgA family Peptidase_S24 PF00717.23 OEU17796.1 - 1.1e-08 34.9 0.1 4.9e-05 23.2 0.0 3.3 3 0 0 3 3 3 2 Peptidase S24-like Peptidase_S26 PF10502.9 OEU17796.1 - 3.8e-06 26.7 0.0 9.7e-05 22.2 0.0 2.7 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Bap31_Bap29_C PF18035.1 OEU17796.1 - 0.2 11.7 7.2 0.43 10.6 7.2 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Myc_N PF01056.18 OEU17796.1 - 0.64 9.9 9.7 1.3 8.8 9.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Macoilin PF09726.9 OEU17796.1 - 0.97 7.9 12.4 1.7 7.1 12.4 1.3 1 0 0 1 1 1 0 Macoilin family 2OG-FeII_Oxy_3 PF13640.6 OEU17799.1 - 0.00024 21.9 0.0 0.0008 20.3 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 OEU17799.1 - 0.0059 16.9 0.0 0.32 11.2 0.0 2.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4124 PF13511.6 OEU17799.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) BppU_IgG PF18667.1 OEU17800.1 - 0.089 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain zf-C3HC4_3 PF13920.6 OEU17801.1 - 0.03 14.2 7.8 0.03 14.2 7.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Imm74 PF15603.6 OEU17801.1 - 0.082 13.1 0.9 0.17 12.1 0.3 1.8 2 0 0 2 2 2 0 Immunity protein 74 zf-Di19 PF05605.12 OEU17801.1 - 0.69 10.3 10.4 1.4 9.2 10.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rad52_Rad22 PF04098.15 OEU17802.1 - 1.5e-28 99.7 0.0 3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SP_C-Propep PF08999.10 OEU17802.1 - 0.035 13.9 3.2 0.064 13.0 3.2 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide RIFIN PF02009.16 OEU17802.1 - 0.34 10.7 1.5 0.34 10.8 0.2 1.5 2 0 0 2 2 2 0 Rifin Orf78 PF06024.12 OEU17802.1 - 0.56 10.5 3.7 0.57 10.5 0.1 2.7 3 0 0 3 3 3 0 Orf78 (ac78) ECSCR PF15820.5 OEU17802.1 - 7 6.5 6.9 17 5.3 6.9 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Chloroa_b-bind PF00504.21 OEU17803.1 - 5.7e-28 98.5 0.7 9e-15 55.6 0.0 2.5 2 1 1 3 3 3 2 Chlorophyll A-B binding protein Glyco_hydro_72 PF03198.14 OEU17804.1 - 2e-48 165.3 0.0 3.2e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Spt5_N PF11942.8 OEU17806.1 - 0.0011 19.9 4.0 0.0011 19.9 4.0 2.2 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 OEU17806.1 - 2.4 8.6 10.2 2.1 8.8 0.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3494 PF11999.8 OEU17808.1 - 1e-34 120.0 7.2 1.2e-34 119.8 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Tyr-DNA_phospho PF06087.12 OEU17809.1 - 2.3e-09 36.7 20.1 0.011 14.6 16.8 4.4 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase Inositol_P PF00459.25 OEU17810.1 - 2.9e-28 99.2 0.1 2.2e-27 96.3 0.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family PAS_9 PF13426.7 OEU17811.1 - 1e-15 57.8 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 OEU17811.1 - 0.00015 21.8 7.4 0.00025 21.0 7.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OEU17811.1 - 0.00034 20.6 8.7 0.00063 19.8 8.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 OEU17811.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OEU17811.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold IATP PF04568.12 OEU17811.1 - 0.089 13.2 1.8 0.22 12.0 1.8 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PAS_8 PF13188.7 OEU17811.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain LrgB PF04172.16 OEU17812.1 - 1.4e-36 126.1 17.8 3.4e-36 124.8 17.8 1.7 1 0 0 1 1 1 1 LrgB-like family RXLR PF16810.5 OEU17812.1 - 0.15 12.5 1.7 0.36 11.3 1.7 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity SR-25 PF10500.9 OEU17812.1 - 0.38 10.3 6.5 0.69 9.5 6.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sigma_reg_N PF13800.6 OEU17812.1 - 3.1 8.1 5.6 0.73 10.2 0.1 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Lact_bio_phlase PF09508.10 OEU17813.1 - 0.0032 16.0 0.4 0.0072 14.8 0.4 1.6 2 0 0 2 2 2 1 Lacto-N-biose phosphorylase N-terminal TIM barrel domain PPR_2 PF13041.6 OEU17814.1 - 1.4e-08 34.8 0.4 0.19 12.0 0.0 6.4 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.20 OEU17814.1 - 2.6e-05 24.2 0.0 0.98 9.8 0.0 5.3 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 OEU17814.1 - 0.016 15.3 1.8 1.8 8.7 0.1 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Vwaint PF14624.6 OEU17814.1 - 0.047 13.8 0.5 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 VWA / Hh protein intein-like DUF1863 PF08937.11 OEU17814.1 - 0.049 13.9 3.7 0.11 12.8 1.9 2.6 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) PPR_1 PF12854.7 OEU17814.1 - 0.054 13.2 2.0 18 5.1 0.0 4.0 4 0 0 4 4 4 0 PPR repeat XAP5 PF04921.14 OEU17814.1 - 2.3 8.0 11.5 0.31 10.8 6.9 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator Aldedh PF00171.22 OEU17815.1 - 1.7e-129 432.4 0.0 9.9e-129 429.8 0.0 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OEU17815.1 - 0.0024 17.0 0.1 0.0047 16.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) FSA_C PF10479.9 OEU17816.1 - 3.7 5.6 10.7 3.7 5.5 10.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus WD40 PF00400.32 OEU17817.1 - 1.2e-08 35.5 7.8 0.016 16.1 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat CRAL_TRIO PF00650.20 OEU17818.1 - 0.0049 16.6 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Tup_N PF08581.10 OEU17818.1 - 0.16 12.3 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Tup N-terminal Glyco_tranf_2_3 PF13641.6 OEU17818.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PTB PF08416.13 OEU17819.1 - 0.044 13.9 0.6 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Enolase_C PF00113.22 OEU17821.1 - 2.4e-117 391.4 0.0 3.1e-117 391.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OEU17821.1 - 4.5e-54 182.2 0.0 6.7e-54 181.6 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OEU17821.1 - 6.9e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OEU17821.1 - 3.2e-05 23.2 0.2 5.9e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF5437 PF17505.2 OEU17821.1 - 0.043 13.9 0.1 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5437) Cyt-b5 PF00173.28 OEU17822.1 - 1.7e-10 40.9 0.1 3.3e-10 40.0 0.1 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 OEU17824.1 - 1.1e-16 60.8 46.7 1.2e-10 40.9 14.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU17824.1 - 1e-07 31.2 28.4 1.8e-05 23.8 28.4 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2304 PF10066.9 OEU17824.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF4131 PF13567.6 OEU17824.1 - 1.7 8.3 7.5 2.5 7.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) MFS_2 PF13347.6 OEU17824.1 - 6.2 5.3 25.2 0.43 9.1 4.1 3.4 3 1 0 3 3 3 0 MFS/sugar transport protein Sulfotransfer_1 PF00685.27 OEU17825.1 - 5.7e-23 81.7 0.0 8.1e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU17825.1 - 0.017 15.5 0.0 1.1 9.5 0.0 2.7 2 1 0 2 2 2 0 Sulfotransferase family DTW PF03942.15 OEU17826.1 - 3.2e-13 49.8 10.7 9.7e-13 48.3 3.3 2.9 2 1 0 2 2 2 2 DTW domain NOZZLE PF08744.10 OEU17826.1 - 0.0043 16.6 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Plant transcription factor NOZZLE SASA PF03629.18 OEU17827.1 - 1.6e-17 64.0 0.0 8.3e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase XPG_I PF00867.18 OEU17828.1 - 1.2e-27 96.1 0.1 2.6e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OEU17828.1 - 0.048 13.1 0.2 0.095 12.2 0.1 1.5 2 0 0 2 2 2 0 XPG domain containing MMR_HSR1 PF01926.23 OEU17829.1 - 2e-20 73.0 0.0 3.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase YchF-GTPase_C PF06071.13 OEU17829.1 - 1.3e-17 63.7 0.0 2.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) FeoB_N PF02421.18 OEU17829.1 - 6.4e-06 25.8 0.0 2.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA PF00004.29 OEU17829.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MatE PF01554.18 OEU17830.1 - 1.2e-15 57.5 11.3 4.9e-09 36.0 0.1 3.4 3 0 0 3 3 3 3 MatE MurJ PF03023.14 OEU17830.1 - 1.5e-06 27.1 0.9 1.5e-06 27.1 0.9 2.7 2 1 1 3 3 3 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 OEU17830.1 - 5.7e-05 23.2 8.1 5.7e-05 23.2 8.1 3.2 2 2 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain NST1 PF13945.6 OEU17831.1 - 2.2 8.3 6.8 3.2 7.8 6.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator GTP_EFTU PF00009.27 OEU17832.1 - 8.2e-28 97.3 0.2 1.2e-27 96.8 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OEU17832.1 - 1.5e-06 28.3 0.1 3.5e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU17832.1 - 0.00031 20.3 0.4 0.034 13.7 0.2 3.0 1 1 1 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OEU17832.1 - 0.00033 20.5 0.3 0.067 13.0 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Septin PF00735.18 OEU17832.1 - 0.00054 19.3 0.2 0.082 12.2 0.0 2.1 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 OEU17832.1 - 0.00089 19.2 2.1 0.44 10.4 0.1 2.6 2 1 1 3 3 3 2 RsgA GTPase Roc PF08477.13 OEU17832.1 - 0.0026 18.0 0.0 2.5 8.3 0.1 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 OEU17832.1 - 0.0032 17.2 0.1 0.44 10.3 0.1 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D3 PF03143.17 OEU17832.1 - 0.0074 16.6 0.1 0.076 13.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain Dynamin_N PF00350.23 OEU17832.1 - 0.019 15.0 0.3 0.046 13.8 0.3 1.6 1 0 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 OEU17832.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4180 PF13788.6 OEU17832.1 - 0.11 12.5 0.1 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4180) Orthopox_F8 PF05886.11 OEU17833.1 - 2.6 8.2 7.2 0.6 10.3 3.3 2.0 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Cupin_8 PF13621.6 OEU17834.1 - 7e-07 29.2 1.7 2.3e-06 27.5 1.7 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OEU17834.1 - 1.5e-05 25.4 2.1 5.9e-05 23.5 0.1 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase JHD PF17811.1 OEU17834.1 - 0.00035 21.1 0.1 0.0014 19.1 0.0 2.1 2 0 0 2 2 2 1 Jumonji helical domain NinG PF05766.12 OEU17835.1 - 0.086 12.8 0.3 0.086 12.8 0.3 2.3 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein Thi4 PF01946.17 OEU17837.1 - 4.9e-05 22.7 0.0 0.0034 16.6 0.0 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 OEU17837.1 - 0.0059 16.8 0.0 0.062 13.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU17837.1 - 0.022 14.8 0.0 0.085 12.8 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU17837.1 - 0.064 12.5 0.0 0.65 9.2 0.0 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 OEU17838.1 - 0.17 12.5 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family GLTSCR1 PF15249.6 OEU17838.1 - 1.7 9.1 7.7 0.24 11.9 0.2 2.9 4 0 0 4 4 4 0 Conserved region of unknown function on GLTSCR protein DUF1349 PF07081.11 OEU17839.1 - 3e-22 79.2 11.7 2.4e-13 50.2 1.7 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1349) IL23 PF16649.5 OEU17839.1 - 0.13 12.3 1.3 1 9.4 0.2 2.2 2 0 0 2 2 2 0 Interleukin 23 subunit alpha MAP70 PF07058.11 OEU17839.1 - 7.1 5.2 6.6 9.7 4.8 6.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 ABC1 PF03109.16 OEU17840.1 - 9.6e-21 74.2 0.0 2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family MFS_1 PF07690.16 OEU17841.1 - 7.2e-16 58.0 13.4 1.3e-08 34.2 1.9 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily RNA_pol_Rbc25 PF08292.12 OEU17842.1 - 0.085 13.1 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 AAA PF00004.29 OEU17843.1 - 4.9e-37 127.3 0.0 8.9e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU17843.1 - 8.1e-09 35.2 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OEU17843.1 - 1.4e-05 25.1 0.0 6.8e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU17843.1 - 1.4e-05 25.5 2.3 0.00033 21.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OEU17843.1 - 1.6e-05 24.7 0.0 4.2e-05 23.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU17843.1 - 7.9e-05 23.0 0.1 0.0016 18.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 OEU17843.1 - 0.00028 20.9 0.0 0.00081 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OEU17843.1 - 0.00032 20.6 3.6 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OEU17843.1 - 0.00038 19.9 0.2 0.0031 16.9 0.3 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OEU17843.1 - 0.00039 20.2 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OEU17843.1 - 0.00069 20.2 0.5 0.0021 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU17843.1 - 0.0011 19.1 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OEU17843.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 OEU17843.1 - 0.0013 18.0 0.1 0.0025 17.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OEU17843.1 - 0.0015 18.7 0.6 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 OEU17843.1 - 0.0015 18.1 0.1 0.029 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OEU17843.1 - 0.0015 18.4 1.4 0.08 12.7 0.1 2.8 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 OEU17843.1 - 0.0037 17.6 0.4 0.01 16.2 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 OEU17843.1 - 0.0066 16.2 0.0 0.0066 16.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 OEU17843.1 - 0.0095 15.9 0.1 0.029 14.4 0.0 1.8 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 OEU17843.1 - 0.012 14.7 0.1 0.012 14.7 0.1 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 OEU17843.1 - 0.013 15.5 0.1 0.03 14.2 0.1 1.6 1 1 0 1 1 1 0 NACHT domain DUF4746 PF15928.5 OEU17843.1 - 0.016 14.7 3.6 0.024 14.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_7 PF12775.7 OEU17843.1 - 0.018 14.5 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 OEU17843.1 - 0.032 13.6 0.0 3.4 7.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein Saw1 PF11561.8 OEU17843.1 - 0.034 13.7 4.9 0.053 13.1 4.9 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 AAA_28 PF13521.6 OEU17843.1 - 0.045 14.0 0.1 0.095 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OEU17843.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2828 PF11443.8 OEU17843.1 - 0.072 11.2 5.1 0.096 10.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA_3 PF07726.11 OEU17843.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAR2 PF05282.11 OEU17843.1 - 0.2 11.1 3.0 0.28 10.6 3.0 1.1 1 0 0 1 1 1 0 AAR2 protein Neur_chan_memb PF02932.16 OEU17843.1 - 0.67 10.0 2.6 0.99 9.4 2.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSRNP_N PF16019.5 OEU17843.1 - 0.8 9.6 5.6 1.2 9.0 5.6 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF3807 PF12720.7 OEU17843.1 - 0.98 9.7 13.6 1.7 8.9 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PIEZO PF15917.5 OEU17843.1 - 1.4 8.3 5.9 2.1 7.8 5.9 1.2 1 0 0 1 1 1 0 Piezo Hydin_ADK PF17213.3 OEU17843.1 - 1.6 9.0 13.5 0.8 10.0 0.2 2.4 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Eapp_C PF10238.9 OEU17843.1 - 2.3 8.3 6.4 4 7.5 6.4 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein ALMT PF11744.8 OEU17843.1 - 4.1 6.1 6.8 5.7 5.7 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 OEU17843.1 - 6.7 5.4 8.4 9.1 4.9 8.4 1.2 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 OEU17844.1 - 4.5 5.7 6.1 4.6 5.7 6.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_2 PF07719.17 OEU17845.1 - 0.032 14.4 0.2 0.2 11.8 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU17845.1 - 0.046 13.8 0.5 0.51 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU17845.1 - 0.062 13.6 0.3 0.39 11.0 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FGGY_N PF00370.21 OEU17846.1 - 4.1e-19 69.1 0.1 1.3e-18 67.5 0.1 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OEU17846.1 - 5.4e-16 58.9 0.0 9.1e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SR-25 PF10500.9 OEU17846.1 - 0.00064 19.4 9.4 0.0056 16.3 3.9 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein HSP70 PF00012.20 OEU17846.1 - 0.02 13.1 0.0 0.032 12.4 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein Lin-8 PF03353.15 OEU17846.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3446 PF11928.8 OEU17846.1 - 0.053 13.8 16.4 0.82 10.0 7.9 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain CCDC106 PF15794.5 OEU17846.1 - 0.095 12.4 0.3 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF1840 PF08895.11 OEU17849.1 - 0.25 11.7 1.1 0.47 10.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) BROMI PF14961.6 OEU17849.1 - 2.1 5.7 6.5 2.5 5.4 6.5 1.0 1 0 0 1 1 1 0 Broad-minded protein ALMT PF11744.8 OEU17849.1 - 4.4 6.0 8.3 5.4 5.7 8.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GOLD_2 PF13897.6 OEU17849.1 - 5.7 7.4 5.8 4 7.9 3.8 1.7 1 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking F-box-like PF12937.7 OEU17851.1 - 0.034 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 F-box-like PRANC PF09372.10 OEU17851.1 - 0.29 11.5 10.1 3.9 7.9 0.0 3.8 3 1 1 4 4 4 0 PRANC domain DNA_pol_phi PF04931.13 OEU17851.1 - 1.6 6.8 9.6 2.3 6.2 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OEU17851.1 - 3.8 7.5 11.1 2.8 7.9 6.5 2.7 3 0 0 3 3 3 0 RXT2-like, N-terminal FAM176 PF14851.6 OEU17851.1 - 6.2 6.5 7.4 12 5.6 7.4 1.4 1 0 0 1 1 1 0 FAM176 family LSM PF01423.22 OEU17852.1 - 1.2e-09 37.8 5.7 2.8e-09 36.5 5.7 1.6 1 1 0 1 1 1 1 LSM domain RPN2_C PF18004.1 OEU17852.1 - 0.19 11.7 11.5 0.014 15.3 6.8 1.8 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Jak1_Phl PF17887.1 OEU17852.1 - 2 8.4 9.2 0.12 12.3 2.7 2.1 1 1 1 2 2 2 0 Jak1 pleckstrin homology-like domain Tyr-DNA_phospho PF06087.12 OEU17853.1 - 3.6e-12 45.9 0.4 0.00011 21.2 0.1 3.1 2 1 1 3 3 3 2 Tyrosyl-DNA phosphodiesterase SET PF00856.28 OEU17854.1 - 0.00038 20.9 0.0 0.00038 20.9 0.0 3.0 2 2 0 2 2 2 1 SET domain Glyco_tranf_2_4 PF13704.6 OEU17855.1 - 0.0041 17.6 0.6 6 7.5 0.1 3.0 2 0 0 2 2 2 2 Glycosyl transferase family 2 Connexin PF00029.19 OEU17855.1 - 0.024 14.4 0.4 0.024 14.4 0.4 2.1 2 0 0 2 2 2 0 Connexin ECSIT_C PF14784.6 OEU17855.1 - 0.071 13.5 1.9 0.16 12.3 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein Zip PF02535.22 OEU17855.1 - 4.2 6.5 8.2 0.7 9.1 1.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Abhydrolase_6 PF12697.7 OEU17856.1 - 0.04 14.5 0.2 0.074 13.6 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU17856.1 - 0.083 12.1 0.1 1.7 7.8 0.1 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Pro_isomerase PF00160.21 OEU17859.1 - 1.6e-11 44.8 0.5 2.2e-11 44.2 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Citrus_P18 PF05520.11 OEU17859.1 - 0.046 13.4 2.9 0.17 11.6 1.6 2.0 1 1 1 2 2 2 0 Citrus tristeza virus P18 protein TFIIA_gamma_C PF02751.14 OEU17859.1 - 2.4 8.4 4.8 0.95 9.7 0.3 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit Vps51 PF08700.11 OEU17860.1 - 0.011 15.7 0.4 0.023 14.8 0.1 1.8 2 1 0 2 2 2 0 Vps51/Vps67 DUF2813 PF11398.8 OEU17860.1 - 0.035 13.4 0.3 0.039 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) vATP-synt_E PF01991.18 OEU17860.1 - 0.08 12.3 0.4 0.089 12.2 0.4 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF3008 PF11450.8 OEU17860.1 - 0.58 10.4 2.4 4.9 7.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) TLD PF07534.16 OEU17861.1 - 3.1e-14 53.4 2.7 3e-10 40.5 0.1 2.7 2 0 0 2 2 2 2 TLD Mucin PF01456.17 OEU17861.1 - 1.9 8.5 13.7 0.24 11.4 1.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Exo_endo_phos PF03372.23 OEU17862.1 - 0.027 14.0 0.0 0.2 11.1 0.0 2.4 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CSTF_C PF14304.6 OEU17863.1 - 0.12 12.0 0.5 0.47 10.1 0.1 2.2 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Med3 PF11593.8 OEU17863.1 - 0.26 10.5 6.8 0.41 9.8 6.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3439 PF11921.8 OEU17863.1 - 0.49 10.4 6.0 1.4 8.9 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 OEU17863.1 - 2.9 5.8 14.2 4.5 5.1 14.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YqfQ PF14181.6 OEU17863.1 - 6 7.0 7.8 16 5.7 7.8 1.8 1 0 0 1 1 1 0 YqfQ-like protein Lipocalin_5 PF13924.6 OEU17864.1 - 0.066 13.0 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Lipocalin-like domain zf-MYND PF01753.18 OEU17865.1 - 1e-10 41.5 9.6 1.8e-10 40.7 9.6 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU17865.1 - 1.8 8.7 6.6 4.3 7.5 6.3 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 LAM_C PF12544.8 OEU17867.1 - 0.0039 17.4 0.1 0.014 15.6 0.1 1.9 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Choline_kinase PF01633.20 OEU17868.1 - 0.00014 21.5 1.0 0.00024 20.8 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 OEU17868.1 - 0.00078 19.4 0.3 0.0047 16.9 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OEU17868.1 - 0.02 14.2 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Ecdysteroid kinase LRAT PF04970.13 OEU17870.1 - 0.036 14.4 6.0 0.068 13.5 0.1 3.2 3 1 1 4 4 4 0 Lecithin retinol acyltransferase G5 PF07501.12 OEU17870.1 - 5.9 7.4 6.3 6.4 7.3 0.1 2.9 3 0 0 3 3 3 0 G5 domain Rubredoxin PF00301.20 OEU17871.1 - 0.079 13.0 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Rubredoxin DUF4746 PF15928.5 OEU17872.1 - 0.0066 15.9 0.2 0.0066 15.9 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) Peptidase_S49_N PF08496.10 OEU17872.1 - 0.42 10.7 20.4 0.023 14.8 7.1 3.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Mucin PF01456.17 OEU17872.1 - 2.3 8.2 7.9 0.26 11.3 2.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Ank_2 PF12796.7 OEU17873.1 - 7e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU17873.1 - 0.00017 22.0 0.0 0.00039 20.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU17873.1 - 0.0011 19.2 0.0 0.021 15.1 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU17873.1 - 0.011 16.2 0.0 0.43 11.3 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 OEU17873.1 - 0.16 12.4 0.0 0.78 10.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat DUF4342 PF14242.6 OEU17874.1 - 0.22 11.6 1.8 0.25 11.3 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4342) EPV_E5 PF08135.11 OEU17874.1 - 0.63 10.5 4.2 1.2 9.6 4.2 1.4 1 0 0 1 1 1 0 Major transforming protein E5 family Hyr1 PF15789.5 OEU17874.1 - 1.1 8.8 3.6 2.1 8.0 3.6 1.4 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 Cupin_8 PF13621.6 OEU17876.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OEU17876.1 - 1.2e-08 35.3 0.0 4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Meleagrin PF08189.11 OEU17876.1 - 0.021 14.5 1.3 0.067 12.9 1.3 1.9 1 0 0 1 1 1 0 Meleagrin/Cygnin family Cupin_1 PF00190.22 OEU17876.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Cupin Lipase_3 PF01764.25 OEU17877.1 - 3.1e-09 36.8 0.0 6.7e-08 32.5 0.0 2.9 3 0 0 3 3 3 1 Lipase (class 3) DUF5544 PF17698.1 OEU17877.1 - 0.051 13.7 1.8 0.39 10.8 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5544) Formyl_trans_N PF00551.19 OEU17879.1 - 7.5e-37 126.8 0.1 1.2e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OEU17879.1 - 5.5e-05 22.9 0.1 0.00011 21.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OEU17879.1 - 0.0069 16.4 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain Plasmid_RAQPRD PF09686.10 OEU17879.1 - 0.15 12.3 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Apc15p PF05841.11 OEU17880.1 - 0.018 15.9 12.5 0.018 15.9 12.5 2.5 2 1 0 2 2 2 0 Apc15p protein DEAD PF00270.29 OEU17881.1 - 9.5e-42 142.7 0.7 6.5e-41 140.0 0.3 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU17881.1 - 1.6e-27 96.0 0.1 4.1e-27 94.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU17881.1 - 3.8e-05 23.7 0.0 0.00018 21.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF285 PF03382.14 OEU17882.1 - 9.5e-136 445.0 94.5 7.9e-36 122.5 16.3 5.0 1 1 3 5 5 5 5 Mycoplasma protein of unknown function, DUF285 U5_2-snRNA_bdg PF10597.9 OEU17882.1 - 0.36 10.9 9.4 7.2 6.7 0.0 4.1 3 1 2 5 5 5 0 U5-snRNA binding site 2 of PrP8 Prok_Ub PF14454.6 OEU17882.1 - 0.47 10.1 4.2 1.8 8.2 0.0 3.5 4 0 0 4 4 4 0 Prokaryotic Ubiquitin THOC2_N PF16134.5 OEU17883.1 - 0.12 11.0 4.9 0.15 10.6 4.9 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Lin-8 PF03353.15 OEU17883.1 - 0.21 11.1 8.6 0.22 11.0 8.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SURF2 PF05477.11 OEU17883.1 - 2.8 7.6 11.2 3.3 7.3 11.2 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MGC-24 PF05283.11 OEU17883.1 - 3.1 8.3 9.4 1.7 9.1 7.2 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ureide_permease PF07168.11 OEU17883.1 - 3.7 6.2 4.8 5.7 5.6 4.8 1.2 1 0 0 1 1 1 0 Ureide permease SLC12 PF03522.15 OEU17883.1 - 6.4 5.7 7.6 7.3 5.5 7.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 OEU17883.1 - 7.6 5.9 11.2 1.2 8.4 7.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SLATT_5 PF18160.1 OEU17884.1 - 0.015 14.7 0.4 0.027 13.8 0.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 SLATT_4 PF18186.1 OEU17884.1 - 0.029 14.0 0.1 0.067 12.8 0.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 BTB_2 PF02214.22 OEU17886.1 - 2e-14 53.7 0.0 3.5e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OEU17886.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Flavin_Reduct PF01613.18 OEU17887.1 - 1.3e-05 25.3 0.1 2.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Flavin reductase like domain KKLCAg1 PF15204.6 OEU17887.1 - 1.6 8.9 6.1 0.7 10.0 0.4 2.8 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 DDE_Tnp_1_7 PF13843.6 OEU17889.1 - 2.3e-17 63.3 0.0 4.2e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 TPR_8 PF13181.6 OEU17892.1 - 0.0014 18.6 0.2 1.1 9.6 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU17892.1 - 0.0023 17.8 0.2 0.22 11.7 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU17892.1 - 0.01 16.1 0.5 0.068 13.5 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU17892.1 - 0.033 14.3 0.0 0.73 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU17892.1 - 0.082 12.8 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIIA PF03153.13 OEU17893.1 - 0.061 13.3 26.7 0.095 12.7 26.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WBP-1 PF11669.8 OEU17893.1 - 0.67 10.6 7.8 3 8.5 7.8 2.1 1 1 0 1 1 1 0 WW domain-binding protein 1 Imm70 PF15601.6 OEU17894.1 - 0.069 12.7 0.9 0.089 12.3 0.9 1.3 1 0 0 1 1 1 0 Immunity protein 70 Rpp20 PF12328.8 OEU17894.1 - 0.084 12.8 0.9 0.13 12.2 0.9 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Pox_A_type_inc PF04508.12 OEU17895.1 - 0.062 13.2 1.5 3 7.8 0.1 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Ank_2 PF12796.7 OEU17896.1 - 0.00031 21.3 0.0 0.068 13.8 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OEU17896.1 - 0.017 15.6 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 OEU17896.1 - 0.053 14.1 0.0 1.1 9.9 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF4710 PF15828.5 OEU17897.1 - 1.5 9.0 10.0 0.55 10.4 6.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF2371 PF10177.9 OEU17897.1 - 6.5 6.9 7.6 14 5.8 5.4 2.3 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) SR-25 PF10500.9 OEU17897.1 - 8.9 5.8 22.6 0.94 9.0 6.5 3.1 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein K_channel_TID PF07941.11 OEU17900.1 - 3 8.4 12.6 14 6.2 0.6 2.6 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PLAC8 PF04749.17 OEU17901.1 - 5.5e-05 24.1 18.0 7.4e-05 23.7 18.0 1.2 1 0 0 1 1 1 1 PLAC8 family CMAS PF02353.20 OEU17902.1 - 3.7e-70 236.3 0.0 5.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NAD_binding_8 PF13450.6 OEU17902.1 - 4.6e-14 52.4 0.0 1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU17902.1 - 6.3e-13 48.8 0.0 1e-12 48.1 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Methyltransf_25 PF13649.6 OEU17902.1 - 2.7e-11 44.0 0.0 6.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU17902.1 - 1.3e-10 41.7 0.0 2.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 OEU17902.1 - 1.2e-07 31.6 0.1 2.2e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_23 PF13489.6 OEU17902.1 - 4e-07 30.0 0.0 9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU17902.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.6 OEU17902.1 - 5.4e-05 23.2 0.0 0.00016 21.7 0.0 1.8 2 0 0 2 2 1 1 FAD-NAD(P)-binding MTS PF05175.14 OEU17902.1 - 0.00082 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Pyr_redox_2 PF07992.14 OEU17902.1 - 0.0023 17.2 1.1 0.0034 16.7 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FtsJ PF01728.19 OEU17902.1 - 0.0033 17.5 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase AlaDh_PNT_C PF01262.21 OEU17902.1 - 0.0047 16.3 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DOT1 PF08123.13 OEU17902.1 - 0.013 15.1 0.3 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 Trp_halogenase PF04820.14 OEU17902.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 OEU17902.1 - 0.019 15.5 0.0 0.054 14.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU17902.1 - 0.046 12.9 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 OEU17902.1 - 0.07 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 OEU17902.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OEU17902.1 - 0.18 10.9 0.1 0.39 9.7 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 OEU17902.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OEU17902.1 - 0.35 10.1 0.9 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ninjurin PF04923.12 OEU17903.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 Ninjurin Serinc PF03348.15 OEU17904.1 - 0.0038 16.2 0.9 0.82 8.5 0.0 2.7 3 0 0 3 3 3 2 Serine incorporator (Serinc) TMEM171 PF15471.6 OEU17904.1 - 0.1 11.6 0.2 6.6 5.6 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein family 171 CENP-K PF11802.8 OEU17904.1 - 0.19 11.2 7.9 0.36 10.4 7.9 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Chalcone_2 PF16035.5 OEU17904.1 - 0.82 9.4 5.9 1.1 9.0 4.9 1.6 1 1 0 1 1 1 0 Chalcone isomerase like CCDC24 PF15669.5 OEU17904.1 - 6.8 6.5 11.8 22 4.8 11.8 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SLAC1 PF03595.17 OEU17905.1 - 6.4e-12 45.4 38.6 8.2e-12 45.0 38.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DPM2 PF07297.12 OEU17905.1 - 0.068 13.5 0.1 0.068 13.5 0.1 2.9 3 0 0 3 3 3 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TPR_2 PF07719.17 OEU17906.1 - 0.55 10.5 3.6 14 6.1 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU17906.1 - 4.6 7.2 7.9 23 5.0 0.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_2 PF00152.20 OEU17907.1 - 5.2e-67 226.2 0.0 7e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 OEU17907.1 - 3.6e-09 36.7 0.0 3.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 OEU17907.1 - 0.00016 21.6 0.2 0.00031 20.6 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OEU17907.1 - 0.0083 15.6 0.6 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.8 OEU17907.1 - 0.91 8.4 6.5 1.4 7.7 6.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 OEU17908.1 - 1.3e-52 178.8 0.0 2.1e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17908.1 - 2.5e-29 102.3 0.0 4.1e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OEU17908.1 - 4.4e-15 55.9 12.1 1.8e-08 34.7 4.3 4.0 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 OEU17908.1 - 3.8e-11 42.6 10.8 5e-07 29.5 0.3 3.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OEU17908.1 - 1.7e-10 39.7 19.9 0.0073 15.8 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 OEU17908.1 - 1e-08 34.4 16.1 0.00028 20.6 0.5 5.2 5 0 0 5 5 5 2 EF-hand domain Pkinase_fungal PF17667.1 OEU17908.1 - 7.7e-05 21.6 0.0 0.00019 20.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OEU17908.1 - 0.00049 19.5 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OEU17908.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 OEU17908.1 - 0.03 14.6 2.2 0.24 11.7 0.2 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Haspin_kinase PF12330.8 OEU17908.1 - 0.039 12.9 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OEU17908.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_4 PF12763.7 OEU17908.1 - 0.66 10.0 5.1 11 6.0 0.1 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ShK PF01549.24 OEU17909.1 - 0.01 16.4 9.4 0.01 16.4 9.4 6.8 5 4 0 5 5 5 0 ShK domain-like P5-ATPase PF12409.8 OEU17909.1 - 1.7 8.8 3.8 8.2 6.6 0.2 3.1 1 1 2 3 3 3 0 P5-type ATPase cation transporter TENA_THI-4 PF03070.16 OEU17910.1 - 9.1e-27 94.2 1.3 1.2e-26 93.8 1.3 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Methyltransf_21 PF05050.12 OEU17911.1 - 3.1e-08 33.8 0.2 4.4e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Fiji_64_capsid PF05880.11 OEU17911.1 - 0.091 11.3 0.0 0.17 10.5 0.0 1.4 2 0 0 2 2 2 0 Fijivirus 64 kDa capsid protein AAA_12 PF13087.6 OEU17912.1 - 2.5e-29 102.3 0.2 2.8e-29 102.2 0.2 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OEU17912.1 - 1.4e-05 24.8 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OEU17912.1 - 0.00017 21.4 0.0 0.00019 21.3 0.0 1.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 OEU17912.1 - 0.00098 18.6 0.1 0.0015 18.0 0.1 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain T3SS_NleG PF06416.12 OEU17913.1 - 0.0079 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Effector protein NleG Band_7 PF01145.25 OEU17914.1 - 1.1e-23 84.1 0.3 1.5e-23 83.7 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OEU17914.1 - 0.00037 20.3 0.2 0.00063 19.5 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pkinase PF00069.25 OEU17915.1 - 2.6e-61 207.3 1.3 4.9e-61 206.4 1.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17915.1 - 5.6e-31 107.8 0.1 8.7e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OEU17915.1 - 1.5e-23 83.0 6.8 1.3e-11 44.8 2.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU17915.1 - 8.4e-19 65.7 13.1 0.00012 21.4 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OEU17915.1 - 8.5e-18 62.7 8.3 8.3e-05 22.2 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OEU17915.1 - 4.7e-17 61.6 10.1 3.1e-09 36.6 0.2 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OEU17915.1 - 6.9e-11 41.1 8.1 0.00083 18.7 0.2 4.5 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 OEU17915.1 - 3.3e-05 24.2 2.5 0.047 14.0 0.1 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 OEU17915.1 - 3.7e-05 22.7 0.0 8e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU17915.1 - 0.00021 20.7 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_11 PF08976.11 OEU17915.1 - 0.0038 18.1 0.4 0.02 15.7 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OEU17915.1 - 0.0043 17.0 3.5 0.41 10.6 0.3 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF5446 PF17522.2 OEU17915.1 - 0.0048 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5446) Kinase-like PF14531.6 OEU17915.1 - 0.015 14.6 0.0 0.23 10.8 0.0 2.3 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 OEU17915.1 - 0.032 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OEU17915.1 - 0.048 13.3 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OEU17915.1 - 0.052 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OEU17916.1 - 4.3e-50 170.5 0.0 6.2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU17916.1 - 2.2e-25 89.4 0.0 4.2e-25 88.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 OEU17916.1 - 6.2e-16 56.9 1.6 0.00038 20.1 0.3 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OEU17916.1 - 5.6e-15 55.6 5.1 3.5e-06 27.4 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OEU17916.1 - 1.1e-13 49.6 5.1 0.0011 18.4 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OEU17916.1 - 1.7e-12 47.0 0.2 7.4e-07 28.9 0.0 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU17916.1 - 3.5e-08 32.6 1.3 0.039 13.5 0.0 3.7 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 OEU17916.1 - 3.8e-05 23.2 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU17916.1 - 0.0023 17.3 0.0 0.014 14.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OEU17916.1 - 0.0052 15.8 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OEU17916.1 - 0.056 13.0 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OEU17916.1 - 0.07 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase H2TH PF06831.14 OEU17917.1 - 2.3e-08 33.9 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-GRF PF06839.12 OEU17917.1 - 2.7e-05 24.2 15.3 0.009 16.1 0.4 3.4 3 0 0 3 3 3 2 GRF zinc finger Fapy_DNA_glyco PF01149.24 OEU17917.1 - 2.8e-05 24.7 0.0 4.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 OEU17917.1 - 0.062 13.2 2.5 0.28 11.1 2.5 2.2 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Dimer_Tnp_hAT PF05699.14 OEU17921.1 - 9e-05 22.2 0.2 9e-05 22.2 0.2 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Glyco_transf_17 PF04724.13 OEU17922.1 - 1.8e-09 37.1 0.0 4.5e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF4692 PF15763.5 OEU17923.1 - 0.017 15.6 0.7 0.021 15.3 0.7 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) JUPITER PF17054.5 OEU17923.1 - 0.079 12.4 4.5 0.1 12.1 4.5 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter DUF1180 PF06679.12 OEU17923.1 - 0.21 12.0 2.7 0.26 11.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF755 PF05501.11 OEU17923.1 - 0.58 10.4 11.7 0.83 9.9 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) IMUP PF15761.5 OEU17923.1 - 3 8.6 14.5 4.2 8.1 14.5 1.4 1 1 0 1 1 1 0 Immortalisation up-regulated protein SOG2 PF10428.9 OEU17924.1 - 0.14 11.4 9.6 0.14 11.4 9.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SelP_N PF04592.14 OEU17924.1 - 0.39 10.1 5.9 0.51 9.7 5.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region EBP50_C PF09007.11 OEU17924.1 - 3.1 8.8 11.7 0.36 11.8 7.3 1.6 2 0 0 2 2 2 0 EBP50, C-terminal TENA_THI-4 PF03070.16 OEU17927.1 - 2.4e-10 40.6 0.0 2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 TENA/THI-4/PQQC family PhyH PF05721.13 OEU17928.1 - 9.4e-11 42.4 0.2 2.5e-10 41.0 0.2 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zip PF02535.22 OEU17929.1 - 0.77 8.9 7.6 1.1 8.4 1.4 2.6 3 0 0 3 3 3 0 ZIP Zinc transporter TMEM174 PF15029.6 OEU17930.1 - 2.2 7.9 7.4 4.3 7.0 7.0 1.7 1 1 0 1 1 1 0 Transmembrane protein 174 Sm_multidrug_ex PF06695.11 OEU17931.1 - 0.0025 18.4 0.9 0.0054 17.4 0.9 1.6 1 1 0 1 1 1 1 Putative small multi-drug export protein BPD_transp_2 PF02653.16 OEU17931.1 - 0.22 10.7 9.3 0.29 10.3 9.3 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF5423 PF17461.2 OEU17931.1 - 1.1 8.0 2.8 1.7 7.4 2.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) PH_BEACH PF14844.6 OEU17932.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH CAP_N PF01213.19 OEU17933.1 - 0.02 14.4 0.2 0.03 13.8 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2254 PF10011.9 OEU17933.1 - 0.058 12.2 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Tnp_P_element_C PF12596.8 OEU17933.1 - 0.43 11.2 5.3 1.2 9.7 4.8 1.8 1 1 0 1 1 1 0 87kDa Transposase BTB PF00651.31 OEU17934.1 - 8.4e-15 55.0 0.1 3.9e-14 52.8 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 OEU17934.1 - 0.00089 19.4 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 MATH domain BTB_2 PF02214.22 OEU17934.1 - 0.0082 16.5 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OEU17934.1 - 0.054 13.6 0.7 0.15 12.2 0.3 2.1 2 0 0 2 2 2 0 BTB And C-terminal Kelch BCNT PF07572.12 OEU17934.1 - 0.057 13.5 0.9 0.88 9.7 0.2 2.3 2 0 0 2 2 2 0 Bucentaur or craniofacial development PP2C PF00481.21 OEU17935.1 - 2.3e-64 217.5 0.1 2.7e-52 178.0 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 OEU17935.1 - 0.0028 17.6 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OEU17935.1 - 0.041 13.5 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C Cupin_4 PF08007.12 OEU17936.1 - 5.8e-17 62.1 0.1 2.8e-16 59.9 0.0 2.2 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU17936.1 - 4e-08 33.3 0.3 4.5e-07 29.8 0.0 2.6 3 0 0 3 3 3 1 Cupin-like domain TRF PF08558.10 OEU17936.1 - 0.002 17.8 1.0 0.0043 16.7 1.0 1.5 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) JmjC PF02373.22 OEU17936.1 - 0.0081 16.6 2.7 0.26 11.7 0.0 3.2 3 1 0 3 3 3 1 JmjC domain, hydroxylase TPR_19 PF14559.6 OEU17936.1 - 0.017 15.6 0.1 0.04 14.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Cupin_1 PF00190.22 OEU17936.1 - 0.028 14.0 0.0 0.082 12.5 0.0 1.8 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 OEU17936.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Tudor_3 PF18115.1 OEU17936.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain HA PF03457.14 OEU17938.1 - 4.7e-71 235.1 11.5 3e-19 69.1 0.1 4.0 4 0 0 4 4 4 4 Helicase associated domain PRC PF05239.16 OEU17938.1 - 3.3e-05 23.9 0.3 2.4 8.3 0.0 3.6 3 1 0 3 3 3 2 PRC-barrel domain DUF3836 PF12930.7 OEU17938.1 - 0.00013 21.7 1.5 3 7.6 0.0 3.2 3 0 0 3 3 3 3 Family of unknown function (DUF3836) Ribosomal_L7Ae PF01248.26 OEU17938.1 - 0.0002 21.0 0.0 2.7 7.8 0.0 3.9 4 0 0 4 4 4 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FixS PF03597.15 OEU17938.1 - 0.015 15.0 2.6 19 5.1 0.0 3.2 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type C_Hendra PF16821.5 OEU17938.1 - 0.027 14.3 0.2 16 5.3 0.0 3.1 2 1 1 3 3 3 0 C protein from hendra and measles viruses Cpta_toxin PF07254.12 OEU17938.1 - 2 8.4 9.3 1.8 8.6 0.2 3.0 4 0 0 4 4 4 0 Membrane-bound toxin component of toxin-antitoxin system HTH_24 PF13412.6 OEU17938.1 - 2.5 7.8 9.2 14 5.3 0.7 3.6 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding Trypan_PARP PF05887.11 OEU17939.1 - 0.095 12.7 0.1 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PI3K_1B_p101 PF10486.9 OEU17939.1 - 0.84 7.3 7.3 0.98 7.1 7.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HNF-1_N PF04814.13 OEU17939.1 - 1.1 9.9 7.6 1.5 9.4 7.6 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF4698 PF15769.5 OEU17939.1 - 2 7.4 6.6 2.3 7.2 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Macoilin PF09726.9 OEU17939.1 - 4.2 5.8 6.9 5.1 5.5 6.9 1.2 1 0 0 1 1 1 0 Macoilin family Mito_carr PF00153.27 OEU17940.1 - 6.4e-18 64.5 1.6 2.1e-05 24.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1129 PF06570.11 OEU17940.1 - 0.098 12.1 0.1 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SET PF00856.28 OEU17941.1 - 0.001 19.5 0.2 0.0019 18.6 0.1 1.6 1 1 0 1 1 1 1 SET domain Dendrin PF15498.6 OEU17941.1 - 0.24 10.1 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin MatE PF01554.18 OEU17942.1 - 2.3e-31 108.6 27.5 1.4e-19 70.3 6.7 2.8 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OEU17942.1 - 1.5e-07 31.5 8.9 1.5e-07 31.5 8.9 3.7 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain LRR_4 PF12799.7 OEU17943.1 - 0.015 15.7 2.3 0.082 13.4 1.5 2.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) OMP_b-brl PF13505.6 OEU17944.1 - 0.00013 22.2 0.2 9.4 6.3 0.0 5.3 1 1 2 3 3 3 1 Outer membrane protein beta-barrel domain Yae1_N PF09811.9 OEU17944.1 - 0.00077 19.1 62.4 25 4.7 0.8 14.1 1 1 5 6 6 6 1 Essential protein Yae1, N terminal Ntox25 PF15530.6 OEU17944.1 - 0.0052 17.0 3.5 32 4.6 0.1 4.9 1 1 4 5 5 5 0 Bacterial toxin 25 Rick_17kDa_Anti PF05433.15 OEU17944.1 - 0.058 13.3 62.0 1.3 9.0 0.5 7.3 4 1 3 7 7 7 0 Glycine zipper 2TM domain Transgly_assoc PF04226.13 OEU17944.1 - 0.14 12.4 50.0 1.8 8.9 0.8 9.8 1 1 8 9 9 9 0 Transglycosylase associated protein MspA PF09203.11 OEU17944.1 - 0.34 10.8 17.1 1.8e+04 -7.2 17.1 4.7 1 1 0 1 1 1 0 MspA Gly-zipper_Omp PF13488.6 OEU17944.1 - 2.6 8.1 50.6 17 5.5 1.0 7.1 1 1 4 5 5 5 0 Glycine zipper HSF_DNA-bind PF00447.17 OEU17945.1 - 6.7e-16 58.7 2.4 2.4e-15 56.9 0.3 2.6 3 0 0 3 3 3 1 HSF-type DNA-binding HA PF03457.14 OEU17945.1 - 1.1e-06 28.8 1.0 1.1e-06 28.8 1.0 2.0 2 0 0 2 2 2 1 Helicase associated domain Pex2_Pex12 PF04757.14 OEU17946.1 - 0.087 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Epimerase PF01370.21 OEU17948.1 - 0.00015 21.3 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_Tnp_ISL3 PF13542.6 OEU17948.1 - 0.07 12.6 0.4 0.16 11.4 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 CAP_GLY PF01302.25 OEU17949.1 - 8.6e-15 54.5 0.1 1.7e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Peptidase_M6 PF05547.11 OEU17950.1 - 1.6e-17 63.1 12.4 3.1e-17 62.2 12.4 1.4 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 EF-hand_1 PF00036.32 OEU17950.1 - 2.2 8.0 6.5 1.3 8.7 2.3 2.4 1 1 1 2 2 2 0 EF hand EF-hand_6 PF13405.6 OEU17950.1 - 2.5 8.3 6.6 0.57 10.3 1.6 2.5 2 1 1 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 OEU17950.1 - 5 6.8 6.0 1.5 8.4 2.0 2.2 2 0 0 2 2 2 0 EF hand Sel1 PF08238.12 OEU17951.1 - 3e-05 24.6 3.1 0.53 11.1 0.0 4.2 5 0 0 5 5 5 2 Sel1 repeat 2OG-FeII_Oxy_3 PF13640.6 OEU17951.1 - 0.00023 22.0 0.9 0.00046 21.0 0.9 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exo_endo_phos PF03372.23 OEU17953.1 - 2e-10 40.6 0.0 3.6e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OEU17953.1 - 0.097 12.5 0.0 2 8.3 0.0 2.3 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Mpv17_PMP22 PF04117.12 OEU17955.1 - 9.6e-09 35.3 0.2 1.8e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ArsP_1 PF03773.13 OEU17955.1 - 0.0073 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Predicted permease Glyco_transf_17 PF04724.13 OEU17956.1 - 6.2e-10 38.6 0.2 2.7e-09 36.5 0.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF2448 PF10476.9 OEU17956.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF5383 PF17355.2 OEU17956.1 - 1.7 9.0 7.6 3.1 8.2 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5383) CIA30 PF08547.12 OEU17957.1 - 7.7e-10 39.0 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Jiraiya PF15038.6 OEU17957.1 - 0.048 13.1 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Jiraiya Orf78 PF06024.12 OEU17957.1 - 0.12 12.7 0.9 0.19 12.0 0.3 1.7 2 0 0 2 2 2 0 Orf78 (ac78) HA PF03457.14 OEU17958.1 - 6.2e-35 119.3 4.9 1.3e-18 67.1 0.6 2.0 2 0 0 2 2 2 2 Helicase associated domain Peptidase_M6 PF05547.11 OEU17958.1 - 0.065 11.6 0.1 0.072 11.4 0.1 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Fasciclin PF02469.22 OEU17960.1 - 1.3e-15 57.7 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain SET PF00856.28 OEU17961.1 - 8e-08 32.9 0.0 3.2e-05 24.4 0.0 3.6 3 1 0 3 3 3 2 SET domain Pex14_N PF04695.13 OEU17963.1 - 0.014 16.0 3.7 0.014 16.0 3.7 4.0 4 1 1 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LCAT PF02450.15 OEU17964.1 - 2.4e-36 125.8 0.4 5.7e-34 117.9 0.0 2.4 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Zip PF02535.22 OEU17965.1 - 0.05 12.8 0.3 0.065 12.4 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-C2H2_assoc2 PF16624.5 OEU17965.1 - 0.15 13.1 9.7 1.1 10.4 6.1 2.3 2 0 0 2 2 2 0 Unstructured region upstream of a zinc-finger CMV_1a PF12467.8 OEU17965.1 - 0.37 11.1 4.9 0.51 10.7 0.5 2.1 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family NINJA_B PF16136.5 OEU17965.1 - 1.5 9.3 9.5 0.78 10.1 3.1 2.1 2 0 0 2 2 2 0 Putative nuclear localisation signal NAD_binding_6 PF08030.12 OEU17966.1 - 5.6e-09 36.3 1.9 8.9e-05 22.7 0.0 2.9 2 1 1 3 3 3 2 Ferric reductase NAD binding domain PMP22_Claudin PF00822.20 OEU17966.1 - 0.004 17.0 0.6 0.0089 15.9 0.6 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family ETRAMP PF09716.10 OEU17966.1 - 0.0058 16.7 0.0 1.1 9.3 0.0 3.2 2 2 1 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) RAMP PF04901.13 OEU17967.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Receptor activity modifying family DUF2070 PF09843.9 OEU17968.1 - 0.28 9.4 8.2 0.5 8.6 8.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5592 PF17332.2 OEU17968.1 - 1.2 9.7 6.3 3 8.5 4.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF3410 PF11890.8 OEU17969.1 - 0.33 10.8 3.0 0.66 9.8 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DUF285 PF03382.14 OEU17970.1 - 2.6e-59 198.3 34.0 9.5e-32 109.3 4.7 4.9 2 2 1 3 3 3 3 Mycoplasma protein of unknown function, DUF285 PT PF04886.12 OEU17970.1 - 0.00019 20.9 13.2 0.00042 19.8 13.2 1.5 1 0 0 1 1 1 1 PT repeat EF-hand_1 PF00036.32 OEU17973.1 - 4e-07 29.1 0.2 0.0012 18.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU17973.1 - 1.5e-05 24.5 0.4 0.83 9.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OEU17973.1 - 2.9e-05 23.3 0.1 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OEU17973.1 - 0.00045 20.6 1.9 0.0016 18.9 0.4 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 OEU17973.1 - 0.00085 19.2 3.4 0.71 9.8 0.0 3.4 2 1 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 OEU17973.1 - 0.0028 17.5 0.0 0.0091 15.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair Lactamase_B PF00753.27 OEU17973.1 - 0.022 14.8 2.0 0.022 14.8 2.0 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OEU17973.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain UPF0492 PF15744.5 OEU17973.1 - 1.5 7.9 15.2 2.6 7.2 15.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Presenilin PF01080.17 OEU17973.1 - 3.7 6.2 11.1 6.2 5.5 11.1 1.3 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 OEU17973.1 - 4.6 7.6 15.4 1.9 8.9 0.1 3.4 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term eRF1_2 PF03464.15 OEU17974.1 - 0.099 13.0 0.7 0.24 11.7 0.3 1.9 2 0 0 2 2 2 0 eRF1 domain 2 Stomoxyn PF11585.8 OEU17974.1 - 1.4 8.9 3.5 33 4.6 0.3 2.7 1 1 1 2 2 2 0 Insect antimicrobial peptide, stomoxyn TAL_FSA PF00923.19 OEU17976.1 - 1e-94 317.1 1.2 1.2e-94 316.9 1.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Alpha_kinase PF02816.18 OEU17977.1 - 3.8e-31 108.6 0.1 7.9e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 OEU17977.1 - 0.0012 19.5 0.0 0.0038 17.8 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OEU17977.1 - 0.045 14.0 0.3 0.33 11.2 0.2 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain SET PF00856.28 OEU17979.1 - 1.9e-08 34.9 7.6 3.4e-05 24.3 0.1 4.2 3 1 0 3 3 3 2 SET domain Zip PF02535.22 OEU17979.1 - 0.16 11.2 1.9 8.4 5.5 0.2 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter adh_short PF00106.25 OEU17980.1 - 1e-31 109.9 0.5 2.3e-31 108.8 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU17980.1 - 1.5e-21 77.1 0.2 6.7e-21 74.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU17980.1 - 8.4e-07 29.1 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Amino_oxidase PF01593.24 OEU17981.1 - 1.2e-56 192.9 0.6 1.2e-56 192.9 0.6 2.1 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU17981.1 - 7.5e-11 42.1 0.2 2.2e-10 40.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OEU17981.1 - 6.4e-05 22.2 0.2 0.00027 20.2 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OEU17981.1 - 0.00021 21.0 0.0 0.00047 19.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU17981.1 - 0.00067 19.0 0.0 0.00067 19.0 0.0 2.1 2 0 0 2 2 1 1 FAD binding domain Thi4 PF01946.17 OEU17981.1 - 0.00068 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OEU17981.1 - 0.0021 18.6 0.9 0.0058 17.2 0.0 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OEU17981.1 - 0.0045 16.3 0.2 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU17981.1 - 0.01 15.1 0.1 0.01 15.1 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OEU17981.1 - 0.013 14.9 0.1 0.013 14.9 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OEU17981.1 - 0.13 11.2 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OEU17981.1 - 0.17 11.0 0.1 0.17 11.0 0.1 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 OEU17981.1 - 0.23 10.1 0.0 0.23 10.1 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein PT PF04886.12 OEU17981.1 - 2.2 7.9 8.8 5.8 6.6 0.5 2.3 2 0 0 2 2 2 0 PT repeat Not1 PF04054.15 OEU17981.1 - 4.4 6.1 5.0 6.7 5.5 5.0 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 CCSAP PF15748.5 OEU17981.1 - 9.7 6.3 10.4 16 5.5 10.4 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ShK PF01549.24 OEU17981.1 - 9.7 6.8 8.3 18 6.0 8.3 1.4 1 0 0 1 1 1 0 ShK domain-like Cation_efflux PF01545.21 OEU17982.1 - 0.067 12.9 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Cation efflux family Presenilin PF01080.17 OEU17982.1 - 0.17 10.6 1.6 0.24 10.1 1.6 1.2 1 0 0 1 1 1 0 Presenilin Red1 PF07964.11 OEU17982.1 - 0.26 9.5 14.3 0.37 9.0 14.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 TPM_phosphatase PF04536.14 OEU17984.1 - 8.1e-12 45.4 4.2 4e-10 39.9 0.2 3.2 2 1 1 3 3 3 1 TPM domain zf-RING_UBOX PF13445.6 OEU17984.1 - 1.3e-07 31.5 4.1 1.3e-07 31.5 4.1 2.1 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU17984.1 - 1.5e-07 31.6 8.8 1.5e-07 31.6 8.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU17984.1 - 3.1e-05 24.2 6.9 3.1e-05 24.2 6.9 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OEU17984.1 - 7.5e-05 22.7 4.3 0.00019 21.4 4.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OEU17984.1 - 0.00022 21.0 4.2 0.0016 18.2 4.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU17984.1 - 0.00022 21.1 7.2 0.00022 21.1 7.2 2.0 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU17984.1 - 0.00035 20.4 5.7 0.00086 19.1 0.8 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OEU17984.1 - 0.00046 20.0 7.6 0.0012 18.7 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OEU17984.1 - 0.0012 18.6 2.9 0.0032 17.3 2.9 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OEU17984.1 - 0.0012 18.6 7.4 0.017 14.9 7.5 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU17984.1 - 0.0043 16.8 10.3 0.01 15.6 7.5 2.8 2 1 0 2 2 2 1 RING-like zinc finger MOLO1 PF17175.4 OEU17984.1 - 0.031 14.4 0.1 0.075 13.2 0.1 1.7 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 Zn-ribbon_8 PF09723.10 OEU17984.1 - 0.072 13.2 2.3 1.5 9.0 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 OEU17984.1 - 0.12 12.5 6.1 0.74 10.0 6.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 OEU17984.1 - 0.28 10.8 6.2 0.12 12.0 3.4 1.9 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Herpes_UL56 PF04534.12 OEU17986.1 - 0.0063 16.0 1.6 0.0077 15.7 0.9 1.5 1 1 0 1 1 1 1 Herpesvirus UL56 protein DUF3439 PF11921.8 OEU17986.1 - 0.055 13.4 2.0 0.059 13.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF913 PF06025.12 OEU17986.1 - 2.5 7.0 6.0 3 6.7 6.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) XPG_I PF00867.18 OEU17987.1 - 1.3e-14 54.3 0.1 1.5e-13 50.9 0.1 3.0 1 0 0 1 1 1 1 XPG I-region SUIM_assoc PF16619.5 OEU17987.1 - 0.0075 16.3 0.0 0.0075 16.3 0.0 8.7 8 2 1 10 10 10 2 Unstructured region C-term to UIM in Ataxin3 XPG_N PF00752.17 OEU17987.1 - 0.016 15.7 0.0 0.83 10.2 0.0 3.0 2 0 0 2 2 2 0 XPG N-terminal domain Otopetrin PF03189.13 OEU17987.1 - 3.9 6.2 0.0 3.9 6.2 0.0 5.1 4 2 0 4 4 4 0 Otopetrin VASt PF16016.5 OEU17988.1 - 3.8e-15 56.6 0.4 1.1e-14 55.1 0.4 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain MAPEG PF01124.18 OEU17988.1 - 0.076 12.9 0.4 0.65 9.9 0.5 2.3 2 0 0 2 2 2 0 MAPEG family EMP24_GP25L PF01105.24 OEU17988.1 - 6.1 6.7 9.3 0.36 10.8 1.3 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD GMC_oxred_N PF00732.19 OEU17989.1 - 2.4e-22 79.7 0.0 1.8e-12 47.2 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OEU17989.1 - 9.2e-21 74.9 0.0 1.7e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_9 PF13454.6 OEU17989.1 - 0.09 12.8 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_L21e PF01157.18 OEU17990.1 - 1.3e-43 147.0 7.8 1.5e-43 146.7 5.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e HAS-barrel PF09378.10 OEU17990.1 - 0.0079 16.3 0.0 0.021 14.9 0.0 1.9 1 1 1 2 2 2 1 HAS barrel domain Ephrin PF00812.17 OEU17990.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.8 1 1 1 2 2 2 0 Ephrin Sas10 PF09368.10 OEU17990.1 - 5.8 7.5 8.3 6.4 7.3 2.0 2.6 3 0 0 3 3 3 0 Sas10 C-terminal domain HA PF03457.14 OEU17991.1 - 6.4e-52 173.8 11.3 2.3e-18 66.3 0.2 3.6 4 0 0 4 4 4 3 Helicase associated domain Ribosomal_L7Ae PF01248.26 OEU17991.1 - 0.011 15.5 0.0 9.3 6.1 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2153 PF09921.9 OEU17991.1 - 0.031 14.1 0.3 3.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2153) DUF5470 PF17564.2 OEU17991.1 - 0.066 13.4 7.8 1.4 9.2 0.1 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5470) VASt PF16016.5 OEU17994.1 - 2.2e-24 86.6 1.1 1e-23 84.4 1.1 2.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OEU17994.1 - 0.012 15.4 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 GRAM domain STI1 PF17830.1 OEU17995.1 - 6.3e-06 26.0 9.0 0.08 12.9 0.4 3.6 3 0 0 3 3 3 3 STI1 domain Nop14 PF04147.12 OEU17995.1 - 3.8 5.6 50.4 0.82 7.8 22.8 3.1 3 0 0 3 3 3 0 Nop14-like family Ank_4 PF13637.6 OEU17997.1 - 1.3e-12 47.9 0.7 8.5e-07 29.4 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU17997.1 - 1.2e-11 45.0 0.0 2.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OEU17997.1 - 1e-09 38.4 0.5 1.9e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OEU17997.1 - 7.3e-09 35.2 0.0 3.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OEU17997.1 - 1.8e-08 34.5 0.0 4.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 OEU17997.1 - 0.061 14.2 0.0 0.18 12.7 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4789 PF16033.5 OEU17997.1 - 0.063 13.8 0.6 0.11 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4789) SUIM_assoc PF16619.5 OEU18000.1 - 9.4 6.4 8.1 23 5.1 2.3 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SAM_2 PF07647.17 OEU18001.1 - 0.00047 20.2 0.1 0.001 19.1 0.1 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OEU18001.1 - 0.0077 16.7 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LapA_dom PF06305.11 OEU18002.1 - 0.084 12.7 0.7 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Zip PF02535.22 OEU18003.1 - 7.7e-37 127.3 14.5 3.3e-35 121.9 14.5 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter MxiM PF11441.8 OEU18004.1 - 0.023 15.0 0.1 1.8 8.8 0.3 2.6 2 0 0 2 2 2 0 Pilot protein MxiM F-box-like PF12937.7 OEU18007.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Aconitase PF00330.20 OEU18009.1 - 0.0085 15.1 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Glyco_transf_11 PF01531.16 OEU18009.1 - 0.035 13.3 0.8 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 11 Aminotran_1_2 PF00155.21 OEU18010.1 - 6.8e-06 25.5 0.0 9.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 OEU18011.1 - 0.0032 16.7 0.0 0.0038 16.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Par3_HAL_N_term PF12053.8 OEU18012.1 - 0.088 13.0 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins Sel1 PF08238.12 OEU18015.1 - 2.1e-08 34.5 0.0 0.0062 17.2 0.0 2.8 2 0 0 2 2 2 2 Sel1 repeat zf-MYND PF01753.18 OEU18015.1 - 0.0085 16.2 12.3 0.0085 16.2 12.3 2.5 2 0 0 2 2 2 1 MYND finger TPR_10 PF13374.6 OEU18015.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.1 5 0 0 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 OEU18016.1 - 3.6e-25 89.3 5.9 2.2e-24 86.8 2.4 2.4 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily LRR_4 PF12799.7 OEU18017.1 - 7.2e-16 58.0 8.2 1.4e-07 31.7 2.3 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU18017.1 - 3.9e-10 39.3 8.4 1.6e-06 27.8 3.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OEU18017.1 - 1.5e-08 34.0 12.5 0.052 13.6 0.2 4.8 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 OEU18017.1 - 3.8e-08 32.8 5.5 0.91 10.3 0.1 5.0 5 0 0 5 5 5 3 Leucine Rich Repeat SAM_Ste50p PF09235.10 OEU18017.1 - 1.3e-05 25.3 1.3 5.6 7.3 0.0 4.3 1 1 4 5 5 5 3 Ste50p, sterile alpha motif SR-25 PF10500.9 OEU18018.1 - 0.092 12.3 10.1 0.21 11.2 10.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TatD_DNase PF01026.21 OEU18020.1 - 1.4e-07 31.2 0.1 2.9e-07 30.1 0.1 1.7 1 1 0 1 1 1 1 TatD related DNase zf-CCHC_2 PF13696.6 OEU18020.1 - 0.0046 16.8 4.1 0.01 15.7 4.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OEU18020.1 - 0.0093 16.0 3.0 0.02 15.0 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 OEU18020.1 - 0.24 11.2 3.2 0.56 10.0 3.2 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 OEU18020.1 - 0.74 9.7 4.7 1.8 8.5 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle cobW PF02492.19 OEU18022.1 - 6.7e-56 188.7 4.3 9.1e-56 188.2 4.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU18022.1 - 1.2e-18 66.9 0.0 1.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OEU18022.1 - 6.4e-05 22.9 1.8 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OEU18022.1 - 0.0045 17.2 0.2 0.011 16.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 OEU18022.1 - 0.0061 16.4 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 OEU18022.1 - 0.0063 15.6 0.1 0.013 14.5 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 OEU18022.1 - 0.0096 15.9 0.3 0.033 14.2 0.1 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 OEU18022.1 - 0.0099 15.8 0.8 0.02 14.8 0.7 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OEU18022.1 - 0.014 15.7 0.1 0.025 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OEU18022.1 - 0.015 15.3 1.6 0.1 12.7 1.2 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 OEU18022.1 - 0.033 13.1 0.1 0.058 12.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 OEU18022.1 - 0.045 14.3 0.3 0.16 12.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OEU18022.1 - 0.052 13.3 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 OEU18022.1 - 0.064 13.5 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OEU18022.1 - 0.18 11.8 5.2 0.3 11.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OEU18022.1 - 1.4 9.4 5.0 3.8 8.0 5.0 2.0 1 1 0 1 1 1 0 ABC transporter p450 PF00067.22 OEU18023.1 - 2.8e-46 158.2 0.0 6.5e-46 157.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.24 OEU18024.1 - 0.0021 17.9 1.9 0.0038 17.1 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FOLN PF09289.10 OEU18024.1 - 0.035 14.3 0.7 0.083 13.1 0.7 1.6 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Torus PF16131.5 OEU18024.1 - 0.046 14.4 0.1 0.1 13.3 0.1 1.7 1 0 0 1 1 1 0 Torus domain WD40 PF00400.32 OEU18025.1 - 6.3e-10 39.5 5.5 1.3e-05 25.8 0.2 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 OEU18025.1 - 1.3e-06 28.2 1.6 0.28 11.2 0.0 5.3 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OEU18025.1 - 0.00048 19.2 0.0 0.0032 16.5 0.0 2.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OEU18025.1 - 0.04 14.2 0.0 1.8 8.9 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 OEU18025.1 - 0.083 11.6 0.2 6.8 5.3 0.1 3.0 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region NiFe_hyd_SSU_C PF14720.6 OEU18025.1 - 0.085 13.2 0.3 0.2 12.1 0.3 1.6 1 0 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal NAD_Gly3P_dh_N PF01210.23 OEU18026.1 - 5.4e-43 146.7 0.0 8.7e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OEU18026.1 - 6.8e-43 146.4 0.0 1.6e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PorB PF11565.8 OEU18026.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 Alpha helical Porin B BTB PF00651.31 OEU18029.1 - 9e-14 51.6 0.4 1.7e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 OEU18029.1 - 2.3e-06 27.7 0.3 1.1e-05 25.5 0.3 2.1 1 1 0 1 1 1 1 MATH domain BACK PF07707.15 OEU18029.1 - 0.072 13.2 0.1 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch Hydrolase_4 PF12146.8 OEU18030.1 - 2.1e-08 33.7 0.1 2.5e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU18030.1 - 1.7e-06 27.7 0.1 0.008 15.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OEU18030.1 - 2.6e-05 24.0 0.6 0.18 11.4 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU18030.1 - 0.015 15.9 0.8 0.25 11.9 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OEU18030.1 - 0.049 13.5 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold RRM_1 PF00076.22 OEU18031.1 - 3.4e-14 52.4 0.0 4.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_N PF00440.23 OEU18031.1 - 0.16 11.8 0.1 0.4 10.5 0.0 1.6 1 1 1 2 2 2 0 Bacterial regulatory proteins, tetR family AAA PF00004.29 OEU18032.1 - 9.6e-41 139.3 0.0 2e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU18032.1 - 7.1e-08 32.1 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OEU18032.1 - 5.5e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OEU18032.1 - 0.00018 21.5 0.1 0.00076 19.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU18032.1 - 0.0011 19.2 0.1 0.0049 17.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU18032.1 - 0.0017 18.7 0.0 0.0075 16.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OEU18032.1 - 0.0061 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 OEU18032.1 - 0.0073 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU18032.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU18032.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU18032.1 - 0.026 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OEU18032.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU18032.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 OEU18032.1 - 0.054 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OEU18032.1 - 0.06 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 OEU18032.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 OEU18032.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OEU18032.1 - 0.12 12.1 0.1 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OEU18032.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OEU18032.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF883 PF05957.13 OEU18034.1 - 0.0016 19.0 13.6 0.0016 19.0 10.3 2.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 OEU18034.1 - 0.002 18.1 4.4 0.0026 17.7 4.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 OEU18034.1 - 0.052 12.4 11.0 0.063 12.1 11.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SpoIIIAH PF12685.7 OEU18034.1 - 0.053 13.3 15.8 0.073 12.9 15.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SNARE PF05739.19 OEU18034.1 - 0.062 13.3 9.9 0.39 10.8 0.6 3.6 2 2 2 4 4 4 0 SNARE domain ApoO PF09769.9 OEU18034.1 - 0.077 13.0 3.6 14 5.6 3.6 2.3 1 1 0 1 1 1 0 Apolipoprotein O ATP-synt_B PF00430.18 OEU18034.1 - 0.086 12.9 12.7 1.2 9.2 13.2 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) YtxH PF12732.7 OEU18034.1 - 0.16 12.5 17.4 3.1e+02 2.0 16.8 2.9 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.11 OEU18034.1 - 0.27 11.3 10.2 0.56 10.3 10.2 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PMEI PF04043.15 OEU18034.1 - 0.27 11.6 12.1 0.38 11.1 12.1 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor HisKA_3 PF07730.13 OEU18034.1 - 0.28 11.7 3.9 58 4.3 3.9 3.1 1 1 0 1 1 1 0 Histidine kinase DUF3552 PF12072.8 OEU18034.1 - 0.32 10.4 12.2 0.38 10.1 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) SH3BP5 PF05276.14 OEU18034.1 - 0.36 10.6 4.9 0.45 10.3 4.9 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Perilipin PF03036.16 OEU18034.1 - 0.61 9.1 19.6 36 3.2 17.7 2.6 1 1 1 2 2 2 0 Perilipin family DAGK_prokar PF01219.19 OEU18034.1 - 0.74 9.7 20.9 1.8 8.4 3.9 3.3 1 1 2 3 3 3 0 Prokaryotic diacylglycerol kinase Alanine_zipper PF11839.8 OEU18034.1 - 0.8 10.1 32.8 58 4.2 4.8 3.3 1 1 1 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein ISG65-75 PF11727.8 OEU18034.1 - 0.92 8.7 19.1 4.9 6.3 19.2 1.8 1 1 0 1 1 1 0 Invariant surface glycoprotein SAPS PF04499.15 OEU18034.1 - 0.93 8.2 5.0 1 8.1 5.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_ligase_A_N PF04675.14 OEU18034.1 - 1.4 9.2 4.8 40 4.5 4.8 2.2 1 1 0 1 1 1 0 DNA ligase N terminus DUF2564 PF10819.8 OEU18034.1 - 1.6 9.1 17.6 10 6.6 1.0 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2564) BAF1_ABF1 PF04684.13 OEU18034.1 - 1.7 7.6 11.7 2.1 7.3 11.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Phasin PF05597.11 OEU18034.1 - 2.2 8.3 9.7 8.5 6.4 2.9 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) KfrA_N PF11740.8 OEU18034.1 - 2.5 8.8 10.6 4 8.1 7.3 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3391 PF11871.8 OEU18034.1 - 3.1 8.3 5.8 25 5.4 5.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) FAM25 PF15825.5 OEU18034.1 - 8.1 6.9 20.3 6.7 7.1 1.3 3.2 1 1 2 3 3 3 0 FAM25 family DUF2431 PF10354.9 OEU18035.1 - 8.3e-23 81.5 0.0 1.6e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF1322 PF07032.11 OEU18035.1 - 0.11 13.0 0.9 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) Chi-conotoxin PF16981.5 OEU18037.1 - 0.049 13.9 0.6 0.075 13.3 0.6 1.3 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily UPF0113_N PF17833.1 OEU18038.1 - 7.7e-31 106.5 0.2 1.5e-30 105.6 0.2 1.5 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OEU18038.1 - 5.9e-24 84.1 0.0 1.1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 OEU18038.1 - 0.045 13.8 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Peptidase_S51 PF03575.17 OEU18039.1 - 7.1e-21 74.8 0.1 5.6e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S51 DAP3 PF10236.9 OEU18040.1 - 1.3e-18 67.3 1.1 1.8e-18 66.8 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OEU18040.1 - 0.001 19.5 0.2 0.0039 17.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 OEU18040.1 - 0.0063 16.5 0.1 0.0063 16.5 0.1 2.7 3 2 0 3 3 3 1 ATPase domain predominantly from Archaea ResIII PF04851.15 OEU18040.1 - 0.0068 16.4 0.1 0.0068 16.4 0.1 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU18040.1 - 0.032 14.5 0.0 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF234 PF03008.14 OEU18040.1 - 0.23 11.9 1.6 1.4 9.4 0.6 2.6 1 1 1 2 2 2 0 Archaea bacterial proteins of unknown function CarD_CdnL_TRCF PF02559.16 OEU18040.1 - 0.33 11.7 2.6 29 5.5 0.0 4.0 3 1 0 3 3 3 0 CarD-like/TRCF domain PMC2NT PF08066.12 OEU18040.1 - 0.42 11.3 11.5 2.1 9.1 0.5 4.0 4 0 0 4 4 4 0 PMC2NT (NUC016) domain MCD PF05292.11 OEU18040.1 - 0.82 9.2 4.5 2.7 7.5 4.4 2.0 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Aa_trans PF01490.18 OEU18041.1 - 2.7e-36 125.2 27.9 5.5e-24 84.6 23.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Crystall_2 PF09076.10 OEU18041.1 - 0.0065 16.3 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 Beta/Gamma crystallin HA PF03457.14 OEU18042.1 - 4e-32 110.3 2.3 8.9e-19 67.6 1.4 2.0 2 0 0 2 2 2 2 Helicase associated domain Melittin PF01372.17 OEU18042.1 - 0.1 12.6 0.2 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Melittin Methyltransf_13 PF08421.11 OEU18043.1 - 0.62 10.4 0.1 0.62 10.4 0.1 2.0 2 0 0 2 2 2 0 Putative zinc binding domain Itfg2 PF15907.5 OEU18044.1 - 0.017 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF2106 PF09879.9 OEU18045.1 - 0.022 14.3 0.1 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) AATase PF07247.12 OEU18046.1 - 0.034 12.7 4.0 0.051 12.1 2.0 2.2 2 1 0 2 2 2 0 Alcohol acetyltransferase CRCB PF02537.15 OEU18046.1 - 0.5 10.7 3.2 13 6.1 0.6 2.7 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Methyltransf_25 PF13649.6 OEU18047.1 - 1.4e-05 25.7 0.9 7e-05 23.5 0.5 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU18047.1 - 1.7e-05 24.6 0.3 0.00014 21.7 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU18047.1 - 3.2e-05 23.8 0.0 6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU18047.1 - 0.00023 21.9 2.8 0.0045 17.7 0.4 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU18047.1 - 0.0065 17.1 2.5 0.01 16.5 0.3 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU18047.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cpn10 PF00166.21 OEU18048.1 - 4.5e-46 154.8 5.0 2.9e-23 81.7 0.1 2.0 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit bZIP_1 PF00170.21 OEU18049.1 - 3.2e-08 33.6 10.1 4.2e-08 33.2 9.0 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU18049.1 - 9.8e-05 22.4 10.7 9.8e-05 22.4 10.7 5.1 6 0 0 6 6 6 1 Basic region leucine zipper BTB PF00651.31 OEU18050.1 - 1.3e-08 35.1 0.1 2e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 OEU18050.1 - 5.3e-06 26.6 0.1 1.4e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 MATH domain SR-25 PF10500.9 OEU18052.1 - 0.041 13.5 4.6 0.06 13.0 4.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CHCH PF06747.13 OEU18053.1 - 0.36 11.0 15.2 0.17 12.1 2.1 4.2 5 0 0 5 5 5 0 CHCH domain Rib_recp_KP_reg PF05104.12 OEU18053.1 - 6.3 7.8 21.0 6.4 7.8 7.9 2.3 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region zf-C4_ClpX PF06689.13 OEU18053.1 - 7.4 6.5 12.0 0.45 10.4 2.1 3.1 3 0 0 3 3 3 0 ClpX C4-type zinc finger KLRAQ PF10205.9 OEU18054.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein zf-MYND PF01753.18 OEU18055.1 - 2.7e-08 33.7 14.2 2.7e-08 33.7 14.2 2.5 3 0 0 3 3 3 1 MYND finger RNA_polI_A34 PF08208.11 OEU18056.1 - 0.18 11.9 11.4 0.32 11.1 11.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3827 PF12877.7 OEU18056.1 - 0.62 8.4 3.8 0.87 7.9 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PMAIP1 PF15150.6 OEU18057.1 - 0.079 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced Mu-like_Com PF10122.9 OEU18057.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com EamA PF00892.20 OEU18058.1 - 1.4e-07 31.8 35.6 5.6e-06 26.6 9.9 5.2 5 2 1 6 6 6 2 EamA-like transporter family SDA1 PF05285.12 OEU18058.1 - 0.0049 16.3 0.9 0.0069 15.9 0.9 1.2 1 0 0 1 1 1 1 SDA1 Pex14_N PF04695.13 OEU18058.1 - 0.095 13.4 0.1 0.095 13.4 0.1 3.2 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M11 PF05548.11 OEU18059.1 - 4.1e-12 45.9 0.0 6.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_3 PF13582.6 OEU18059.1 - 0.069 13.7 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU18059.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin ShK PF01549.24 OEU18059.1 - 3.5 8.2 9.7 9.7 6.8 9.7 1.8 1 1 0 1 1 1 0 ShK domain-like PikAIV_N PF18605.1 OEU18060.1 - 2.8 7.6 5.1 2.1 8.0 3.1 1.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Pilosulin PF17499.2 OEU18060.1 - 3.4 7.9 4.3 34 4.7 1.3 2.8 1 1 2 3 3 3 0 Ant venom peptides DUF2244 PF10003.9 OEU18061.1 - 7.8 6.2 9.0 4.5 6.9 7.6 1.4 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) YadA_head PF05658.14 OEU18062.1 - 7.6e-05 23.0 0.8 7.6e-05 23.0 0.8 5.8 5 1 2 7 7 7 3 Head domain of trimeric autotransporter adhesin DUF4973 PF16343.5 OEU18062.1 - 0.077 13.0 0.3 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) Atg14 PF10186.9 OEU18062.1 - 0.54 9.3 5.3 1.2 8.2 5.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 OEU18062.1 - 1.5 8.1 4.3 2.7 7.3 4.3 1.4 1 0 0 1 1 1 0 FAM76 protein DUF563 PF04577.14 OEU18063.1 - 0.047 13.8 0.1 0.86 9.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF563) Cadherin_C_2 PF16492.5 OEU18063.1 - 0.09 13.5 1.0 0.82 10.5 0.0 3.2 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal YajC PF02699.15 OEU18063.1 - 0.95 9.4 11.4 0.99 9.3 0.0 3.6 4 0 0 4 4 4 0 Preprotein translocase subunit TFB6 PF17110.5 OEU18063.1 - 4.7 6.9 7.2 1.5 8.5 1.2 2.9 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 OEU18063.1 - 5.5 6.1 10.0 0.69 9.1 4.3 2.3 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 OEU18063.1 - 7.7 6.2 11.6 3 7.5 0.0 3.7 5 0 0 5 5 5 0 Connexin potato_inhibit PF00280.18 OEU18064.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 Potato inhibitor I family Peptidase_A21 PF03566.13 OEU18064.1 - 0.044 12.1 0.8 0.062 11.6 0.8 1.2 1 0 0 1 1 1 0 Peptidase family A21 PT PF04886.12 OEU18064.1 - 0.098 12.2 3.9 0.19 11.3 3.9 1.4 1 0 0 1 1 1 0 PT repeat Dishevelled PF02377.15 OEU18064.1 - 0.13 12.8 7.4 0.15 12.5 3.7 2.3 2 0 0 2 2 2 0 Dishevelled specific domain REV PF00424.18 OEU18064.1 - 1.5 8.9 9.9 25 5.0 0.1 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CobN-Mg_chel PF02514.16 OEU18066.1 - 0 1110.3 0.0 0 1109.8 0.0 1.2 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 OEU18066.1 - 4e-50 170.1 0.9 8.4e-50 169.0 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) NYN_YacP PF05991.11 OEU18067.1 - 0.0022 17.9 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 YacP-like NYN domain PhoQ_Sensor PF08918.10 OEU18070.1 - 7.9 6.3 7.6 0.38 10.6 1.6 1.9 2 0 0 2 2 2 0 PhoQ Sensor Ribosomal_S20p PF01649.18 OEU18071.1 - 0.42 11.3 2.8 1.6 9.5 2.8 1.9 1 1 0 1 1 1 0 Ribosomal protein S20 LIN37 PF15306.6 OEU18072.1 - 0.083 13.1 3.1 1.2 9.4 0.2 2.4 2 0 0 2 2 2 0 LIN37 SnoaL_3 PF13474.6 OEU18073.1 - 1.2e-12 48.2 0.2 7.3e-12 45.6 0.2 2.1 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OEU18073.1 - 8.8e-05 23.1 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OEU18073.1 - 0.00015 22.1 0.0 0.001 19.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) His_Phos_2 PF00328.22 OEU18075.1 - 1.3e-43 149.8 0.0 2.4e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OEU18075.1 - 1.5e-34 118.0 0.1 3.9e-34 116.7 0.1 1.8 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OEU18075.1 - 0.066 12.8 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain His_Phos_2 PF00328.22 OEU18076.1 - 2.7e-10 40.1 0.0 2.7e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Hamartin PF04388.12 OEU18076.1 - 0.62 8.7 9.1 0.8 8.3 9.1 1.1 1 0 0 1 1 1 0 Hamartin protein Nucleo_P87 PF07267.11 OEU18076.1 - 0.7 8.7 9.8 0.88 8.3 9.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BTB_2 PF02214.22 OEU18078.1 - 9.1e-14 51.6 0.0 2.2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Replicase PF03090.17 OEU18079.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Replicase family SWI-SNF_Ssr4 PF08549.10 OEU18080.1 - 2.4 6.7 16.8 0.25 9.9 11.1 2.0 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Metallophos PF00149.28 OEU18081.1 - 1.3e-09 38.9 0.1 1.9e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CCSAP PF15748.5 OEU18082.1 - 0.75 9.9 13.2 2.3 8.3 2.3 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Fer4_13 PF13370.6 OEU18083.1 - 2.4e-14 53.6 2.7 4.5e-14 52.7 2.7 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OEU18083.1 - 4.1e-09 37.1 2.1 1.5e-08 35.3 2.1 2.0 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 OEU18083.1 - 0.00023 21.2 1.4 0.00041 20.4 1.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 OEU18083.1 - 0.014 15.1 6.8 0.053 13.4 1.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 OEU18083.1 - 0.042 13.9 1.1 0.042 13.9 1.1 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Lar_restr_allev PF14354.6 OEU18083.1 - 0.056 13.8 0.4 0.1 13.0 0.4 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar c-SKI_SMAD_bind PF08782.10 OEU18083.1 - 0.067 13.4 0.0 0.22 11.8 0.1 1.7 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Fer4_7 PF12838.7 OEU18083.1 - 0.12 12.9 4.2 0.34 11.5 3.6 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fea1 PF07692.11 OEU18084.1 - 1.8e-06 27.2 0.0 3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Low iron-inducible periplasmic protein EF-hand_6 PF13405.6 OEU18084.1 - 0.035 14.0 7.3 4.7 7.4 0.0 4.7 4 1 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 OEU18084.1 - 0.037 13.6 17.6 1 9.1 0.0 5.8 6 0 0 6 6 6 0 EF hand Myb_DNA-binding PF00249.31 OEU18085.1 - 3.2e-08 33.6 0.1 9e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cupin_8 PF13621.6 OEU18086.1 - 3.9e-07 30.0 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OEU18086.1 - 0.00012 22.4 0.1 0.00043 20.7 0.0 1.9 1 1 1 2 2 2 1 JmjC domain, hydroxylase DUF285 PF03382.14 OEU18087.1 - 5.1e-127 416.8 89.6 7.2e-35 119.4 15.6 3.1 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 YpsA PF06908.11 OEU18087.1 - 0.0023 18.0 8.9 0.89 9.5 2.0 3.2 1 1 1 3 3 3 2 YspA SLOG family DUF5068 PF16781.5 OEU18087.1 - 0.0032 17.3 1.7 1 9.1 0.2 3.0 1 1 3 4 4 4 2 Domain of unknown function (DUF5068) DegQ PF08181.11 OEU18087.1 - 0.095 12.8 0.2 13 6.0 0.0 3.0 2 0 0 2 2 2 0 DegQ (SacQ) family CPSase_L_D3 PF02787.19 OEU18087.1 - 0.16 12.3 1.5 1.7 9.0 0.2 2.9 1 1 2 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Tubulin-binding PF00418.19 OEU18087.1 - 0.21 11.7 2.0 65 3.7 0.0 4.0 3 0 0 3 3 3 0 Tau and MAP protein, tubulin-binding repeat DUF3932 PF13068.6 OEU18087.1 - 0.61 10.4 31.8 0.85 9.9 0.1 6.7 4 2 3 7 7 7 0 Protein of unknown function (DUF3932) Csm2_III-A PF03750.13 OEU18087.1 - 0.71 10.7 2.8 26 5.7 0.2 3.2 1 1 1 3 3 3 0 Csm2 Type III-A Spermine_synth PF01564.17 OEU18088.1 - 5.4e-09 35.7 0.2 5.1e-07 29.3 0.0 2.7 2 1 1 3 3 3 2 Spermine/spermidine synthase domain SET PF00856.28 OEU18088.1 - 3.8e-06 27.4 0.2 3.8e-06 27.4 0.2 2.9 4 1 0 4 4 4 1 SET domain Sigma70_ner PF04546.13 OEU18088.1 - 0.053 13.4 5.7 1.9 8.3 1.6 3.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Polyketide_cyc PF03364.20 OEU18090.1 - 6.4e-07 29.6 0.0 3.8e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport IMUP PF15761.5 OEU18090.1 - 1.3 9.8 6.2 2.9 8.6 6.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein NOA36 PF06524.12 OEU18090.1 - 3.1 7.0 8.1 4.4 6.5 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein KCNQ2_u3 PF16642.5 OEU18091.1 - 8.7 7.4 12.2 0.11 13.5 2.2 2.7 2 1 0 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 BTB PF00651.31 OEU18092.1 - 5.3e-11 42.7 0.1 2e-10 40.9 0.1 2.0 1 1 1 2 2 2 1 BTB/POZ domain DUF3342 PF11822.8 OEU18092.1 - 0.0042 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Spem1 PF15670.5 OEU18096.1 - 0.035 13.7 1.5 0.042 13.4 1.5 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 UspA1_rep PF18792.1 OEU18097.1 - 1.4e-14 53.1 84.8 0.012 16.0 0.4 12.1 12 0 0 12 12 12 8 Ubiquitous surface protein adhesin repeat YadA_head PF05658.14 OEU18097.1 - 7.7e-05 23.0 0.4 7.7e-05 23.0 0.4 7.3 8 2 0 8 8 8 1 Head domain of trimeric autotransporter adhesin DUF4361 PF14274.6 OEU18097.1 - 0.12 12.7 1.6 0.19 12.0 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) NYD-SP28 PF14772.6 OEU18097.1 - 0.14 12.3 6.8 0.22 11.6 6.8 1.3 1 0 0 1 1 1 0 Sperm tail DUF2748 PF10871.8 OEU18097.1 - 0.17 10.5 4.6 0.24 10.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Med9 PF07544.13 OEU18097.1 - 0.74 9.9 8.1 1.2 9.2 8.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 OEU18097.1 - 1.9 9.2 6.1 3.2 8.4 5.3 1.7 1 1 1 2 2 2 0 SlyX SnoaL_2 PF12680.7 OEU18098.1 - 0.049 14.3 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain Acetyltransf_7 PF13508.7 OEU18099.1 - 4.3e-08 33.5 0.0 8.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU18099.1 - 1.8e-07 31.4 0.0 0.00016 21.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 OEU18099.1 - 2.1e-05 24.4 0.0 0.0074 16.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 OEU18099.1 - 3.3e-05 23.8 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU18099.1 - 0.00011 22.2 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ETRAMP PF09716.10 OEU18099.1 - 0.0074 16.3 0.4 0.033 14.2 0.5 2.1 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) SSP160 PF06933.11 OEU18099.1 - 0.01 14.1 6.0 0.013 13.8 6.0 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Pet127 PF08634.10 OEU18099.1 - 0.039 13.4 1.2 0.046 13.1 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet127 DUF957 PF06117.11 OEU18099.1 - 0.057 13.0 1.0 0.14 11.8 1.0 1.6 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Pox_G5 PF04599.12 OEU18100.1 - 0.099 11.6 1.4 0.16 11.0 1.4 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein DUF2201_N PF13203.6 OEU18100.1 - 0.16 11.6 3.7 0.34 10.5 3.7 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Tho2 PF11262.8 OEU18100.1 - 0.25 10.5 4.5 0.38 9.9 4.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 OEU18100.1 - 0.3 10.4 5.3 0.51 9.6 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Utp14 PF04615.13 OEU18100.1 - 0.35 9.4 21.5 0.64 8.5 21.5 1.4 1 0 0 1 1 1 0 Utp14 protein DUF2951 PF11166.8 OEU18100.1 - 0.4 10.9 3.9 1.1 9.5 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF3499 PF12005.8 OEU18100.1 - 0.51 11.0 5.4 0.37 11.4 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3499) Fasciclin PF02469.22 OEU18101.1 - 3.4e-33 114.6 0.0 9.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Pep_deformylase PF01327.21 OEU18101.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Polypeptide deformylase BRK PF07533.16 OEU18101.1 - 0.27 10.9 2.3 0.43 10.2 0.3 2.3 2 1 1 3 3 3 0 BRK domain Fasciclin PF02469.22 OEU18102.1 - 1.2e-53 180.7 0.0 6.4e-20 71.7 0.0 3.4 3 0 0 3 3 3 3 Fasciclin domain Fasciclin PF02469.22 OEU18104.1 - 1.4e-20 73.8 0.0 2.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain SNF PF00209.18 OEU18105.1 - 6.2e-46 157.2 54.0 2.9e-29 102.2 25.4 3.9 2 1 1 3 3 3 2 Sodium:neurotransmitter symporter family LapA_dom PF06305.11 OEU18105.1 - 2.8 7.8 7.6 24 4.9 0.1 4.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain HMG_box PF00505.19 OEU18106.1 - 3.2e-14 53.1 4.8 7.7e-14 51.9 4.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.23 OEU18106.1 - 5.4e-13 49.0 0.1 1.7e-12 47.4 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box_2 PF09011.10 OEU18106.1 - 3e-10 40.5 3.0 9.9e-10 38.9 3.0 1.9 1 1 0 1 1 1 1 HMG-box domain Histone PF00125.24 OEU18106.1 - 4e-05 24.0 1.4 4e-05 24.0 1.4 3.0 2 2 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OEU18106.1 - 0.00014 21.9 0.4 0.00082 19.5 0.0 2.1 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CDC45 PF02724.14 OEU18106.1 - 0.021 13.1 17.5 0.029 12.7 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CHDNT PF08073.12 OEU18106.1 - 0.044 13.7 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain Nop14 PF04147.12 OEU18106.1 - 1.9 6.6 21.2 3.3 5.8 21.2 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_49 PF13896.6 OEU18107.1 - 3.8e-36 125.1 8.2 7.8e-32 110.9 6.5 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.9 OEU18107.1 - 0.029 13.8 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Fasciclin PF02469.22 OEU18108.1 - 2.6e-34 118.2 0.0 7e-18 65.1 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain PT PF04886.12 OEU18108.1 - 5.5 6.6 27.7 1.8e+04 -5.9 27.7 2.9 1 1 0 1 1 1 0 PT repeat DAGK_cat PF00781.24 OEU18109.1 - 0.033 13.8 0.2 0.57 9.8 0.0 2.4 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain DUF4179 PF13786.6 OEU18110.1 - 0.072 13.6 0.3 0.61 10.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF1980 PF09323.10 OEU18110.1 - 1.2 9.1 5.3 0.19 11.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CDK2AP PF09806.9 OEU18110.1 - 3.8 7.5 8.8 0.22 11.6 2.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Bestrophin PF01062.21 OEU18111.1 - 2e-17 63.5 0.1 2.2e-08 33.9 0.0 2.5 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 OEU18112.1 - 3.6e-18 66.0 1.6 4.9e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Phage_holin_8 PF16931.5 OEU18113.1 - 0.046 13.7 0.5 0.046 13.7 0.5 1.8 2 0 0 2 2 2 0 Putative phage holin Erv26 PF04148.13 OEU18114.1 - 0.0016 18.3 0.1 0.0035 17.2 0.1 1.6 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 CD225 PF04505.12 OEU18114.1 - 0.0038 17.3 0.7 0.0038 17.3 0.7 1.9 2 0 0 2 2 2 1 Interferon-induced transmembrane protein Diphtheria_T PF02764.14 OEU18114.1 - 0.013 15.5 0.7 0.025 14.6 0.7 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain SieB PF14163.6 OEU18114.1 - 0.1 12.1 0.7 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B FAM176 PF14851.6 OEU18114.1 - 1.2 8.8 6.4 17 5.1 5.5 2.9 3 0 0 3 3 3 0 FAM176 family zf-CHCC PF10276.9 OEU18115.1 - 0.48 10.5 3.1 6.7 6.9 1.5 2.6 2 1 0 2 2 2 0 Zinc-finger domain HA PF03457.14 OEU18116.1 - 2.1e-52 175.3 7.7 4.3e-18 65.4 0.3 3.1 3 0 0 3 3 3 3 Helicase associated domain EPL1 PF10513.9 OEU18116.1 - 0.0067 16.8 0.8 0.013 15.9 0.8 1.5 1 1 0 1 1 1 1 Enhancer of polycomb-like Antirestrict PF03230.13 OEU18116.1 - 0.022 14.8 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Antirestriction protein PMR5N PF14416.6 OEU18116.1 - 0.042 14.2 0.9 49 4.3 0.1 4.0 4 0 0 4 4 4 0 PMR5 N terminal Domain NDUF_B4 PF07225.12 OEU18116.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Bestrophin PF01062.21 OEU18118.1 - 4.9e-19 68.8 0.2 1.6e-17 63.8 0.2 2.2 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Mito_carr PF00153.27 OEU18119.1 - 3.4e-42 142.3 5.6 6e-16 58.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SpoV PF08183.11 OEU18119.1 - 0.015 15.2 1.1 0.041 13.8 1.1 1.7 1 0 0 1 1 1 0 Stage V sporulation protein family TrmB PF01978.19 OEU18120.1 - 0.033 14.1 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 OEU18120.1 - 0.091 12.7 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 HTH domain Asp-B-Hydro_N PF05279.11 OEU18120.1 - 7.6 6.5 20.2 3.5 7.6 2.2 2.4 2 1 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region zf-C3HC4_3 PF13920.6 OEU18122.1 - 0.00026 20.8 12.0 0.0004 20.2 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 OEU18122.1 - 0.00099 19.1 6.6 0.00099 19.1 6.6 1.5 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 OEU18122.1 - 0.0024 18.1 13.3 0.0044 17.3 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain Rad50_zn_hook PF04423.14 OEU18122.1 - 0.0059 16.4 1.8 3.6 7.5 0.0 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif Prok-RING_4 PF14447.6 OEU18122.1 - 0.15 12.0 10.6 0.2 11.6 4.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OEU18122.1 - 0.43 10.4 13.9 0.83 9.6 13.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU18122.1 - 0.48 10.6 9.7 0.92 9.7 9.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C4_Topoisom PF01396.19 OEU18122.1 - 0.96 9.3 0.0 0.96 9.3 0.0 2.9 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-RING_5 PF14634.6 OEU18122.1 - 1.6 8.8 12.1 4 7.5 7.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain ATG22 PF11700.8 OEU18124.1 - 0.026 13.1 0.9 0.042 12.5 0.9 1.4 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like MSP1a PF11670.8 OEU18124.1 - 0.058 12.7 0.5 0.11 11.8 0.5 1.6 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) Orf78 PF06024.12 OEU18124.1 - 0.14 12.5 0.4 0.14 12.5 0.4 4.5 3 1 0 3 3 3 0 Orf78 (ac78) ABC2_membrane_3 PF12698.7 OEU18124.1 - 0.28 10.2 6.8 0.52 9.4 6.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Goodbye PF17109.5 OEU18124.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.6 2 1 2 4 4 4 0 fungal STAND N-terminal Goodbye domain SID-1_RNA_chan PF13965.6 OEU18124.1 - 5.3 5.3 15.2 58 1.9 15.3 1.9 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 IstB_IS21 PF01695.17 OEU18125.1 - 0.023 14.4 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-RING_2 PF13639.6 OEU18127.1 - 4.3e-09 36.5 4.4 9e-09 35.5 4.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OEU18127.1 - 9e-07 28.8 5.1 1.5e-06 28.0 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OEU18127.1 - 8.3e-06 25.4 4.9 2.1e-05 24.1 4.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU18127.1 - 1.6e-05 24.7 3.2 1.6e-05 24.7 3.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU18127.1 - 1.8e-05 24.7 0.8 3.4e-05 23.8 0.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU18127.1 - 0.0021 17.9 10.7 0.075 12.9 10.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU18127.1 - 0.0071 16.6 8.5 0.13 12.6 8.5 2.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OEU18127.1 - 0.061 13.2 5.5 1.5 8.7 5.5 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OEU18127.1 - 0.1 12.6 3.1 0.28 11.2 3.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 OEU18127.1 - 0.12 12.5 6.0 0.15 12.2 4.6 1.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain Glyco_hydro_31 PF01055.26 OEU18127.1 - 0.19 10.9 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 DZR PF12773.7 OEU18127.1 - 0.2 11.7 5.5 0.91 9.6 5.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-HC5HC2H PF13771.6 OEU18127.1 - 0.25 11.6 6.6 0.27 11.5 5.1 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.29 OEU18127.1 - 0.27 11.2 9.0 1.1 9.2 7.0 2.2 1 1 1 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 OEU18127.1 - 0.3 10.7 7.7 0.098 12.3 1.9 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 OEU18127.1 - 0.37 10.8 9.0 2.5 8.1 2.0 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OEU18127.1 - 0.69 10.1 6.3 4.4 7.6 6.3 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OEU18127.1 - 0.8 9.6 10.5 2.9 7.8 8.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4451 PF14616.6 OEU18127.1 - 1.2 9.3 7.0 2.5 8.3 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Lipase_GDSL_2 PF13472.6 OEU18128.1 - 5.7e-10 39.9 0.2 1.4e-09 38.6 0.0 1.7 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU18128.1 - 1.3e-06 28.6 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-C2H2 PF00096.26 OEU18129.1 - 0.047 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Lin-8 PF03353.15 OEU18129.1 - 0.8 9.2 9.1 0.52 9.8 6.5 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CNDH2_C PF16858.5 OEU18129.1 - 5.5 6.8 13.9 11 5.8 13.9 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Ldh_2 PF02615.14 OEU18131.1 - 0.048 12.8 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase PRANC PF09372.10 OEU18132.1 - 0.0021 18.4 0.4 0.012 15.9 0.0 2.3 3 1 0 3 3 3 1 PRANC domain Phage_int_SAM_3 PF14659.6 OEU18132.1 - 0.075 13.3 0.2 12 6.3 0.1 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain F-box-like PF12937.7 OEU18132.1 - 0.16 11.9 0.1 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 F-box-like K1 PF02960.14 OEU18132.1 - 0.21 11.7 0.5 0.43 10.7 0.1 1.7 2 0 0 2 2 2 0 K1 glycoprotein SpoU_methylase PF00588.19 OEU18134.1 - 3.3e-16 59.7 3.1 9.2e-12 45.3 0.0 3.3 3 1 0 3 3 3 2 SpoU rRNA Methylase family NOA36 PF06524.12 OEU18134.1 - 0.24 10.7 2.6 0.36 10.1 2.6 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 OEU18134.1 - 0.35 11.1 7.8 0.086 13.1 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) VPS13_C PF16909.5 OEU18135.1 - 5.6e-06 26.3 0.1 8.5e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal DUF2232 PF09991.9 OEU18135.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) RCR PF12273.8 OEU18136.1 - 1.6e-05 25.5 0.7 0.0033 18.1 0.3 3.3 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF1229 PF06797.11 OEU18136.1 - 0.00058 20.1 4.9 0.001 19.3 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Tetraspanin PF00335.20 OEU18136.1 - 0.001 18.8 3.1 0.001 18.8 3.1 1.7 2 0 0 2 2 2 1 Tetraspanin family CaM_bdg_C0 PF10562.9 OEU18137.1 - 2.2 8.4 4.9 24 5.1 0.8 2.5 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF4551 PF15087.6 OEU18139.1 - 6.4 5.5 25.9 1.8 7.3 15.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) ClpS PF02617.17 OEU18140.1 - 0.00073 19.3 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Draxin PF15550.6 OEU18141.1 - 6.9 6.4 14.0 0.58 10.0 8.9 1.7 2 0 0 2 2 2 0 Draxin ATPase_gene1 PF09527.10 OEU18142.1 - 0.065 13.4 1.6 0.065 13.4 1.6 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter zf-MYND PF01753.18 OEU18143.1 - 3.3e-09 36.7 6.6 1.1e-08 35.1 6.6 2.0 1 0 0 1 1 1 1 MYND finger POP1 PF06978.11 OEU18143.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 bZIP_1 PF00170.21 OEU18144.1 - 0.0015 18.6 17.1 0.0049 16.9 17.1 2.0 1 0 0 1 1 1 1 bZIP transcription factor HA PF03457.14 OEU18145.1 - 5.2e-14 52.3 0.6 5.2e-14 52.3 0.6 3.2 2 0 0 2 2 2 1 Helicase associated domain ALGX PF16822.5 OEU18146.1 - 0.023 14.4 1.4 0.031 13.9 1.4 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Peptidase_M17_N PF02789.17 OEU18146.1 - 0.44 10.4 3.4 1.8 8.4 0.6 2.8 3 0 0 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain HA PF03457.14 OEU18147.1 - 2.9e-36 123.6 1.2 4.2e-18 65.4 0.2 2.2 2 0 0 2 2 2 2 Helicase associated domain NPR3 PF03666.13 OEU18147.1 - 2.3 6.9 9.8 3.1 6.5 9.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GET2 PF08690.10 OEU18147.1 - 2.5 7.7 7.7 0.74 9.4 5.2 1.4 2 0 0 2 2 2 0 GET complex subunit GET2 PBP1_TM PF14812.6 OEU18147.1 - 7.9 6.9 13.6 15 6.0 13.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fasciclin PF02469.22 OEU18148.1 - 6.9e-12 45.7 0.0 1.4e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain TMEM173 PF15009.6 OEU18148.1 - 0.33 10.1 0.9 0.41 9.8 0.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 Claudin_3 PF06653.11 OEU18148.1 - 0.83 9.6 6.2 1.2 9.0 6.2 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Fasciclin PF02469.22 OEU18149.1 - 1.9e-10 41.1 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain zf-MYND PF01753.18 OEU18152.1 - 2.1e-07 30.9 14.8 4e-07 30.0 14.8 1.5 1 0 0 1 1 1 1 MYND finger IR1-M PF12185.8 OEU18155.1 - 0.011 15.6 6.7 0.011 15.6 0.2 3.5 4 0 0 4 4 4 0 Nup358/RanBP2 E3 ligase domain BTB_2 PF02214.22 OEU18156.1 - 0.00025 21.3 0.1 0.00083 19.7 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Colicin-DNase PF12639.7 OEU18158.1 - 0.43 11.4 0.1 0.43 11.4 0.1 3.1 3 0 0 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin Neur_chan_memb PF02932.16 OEU18159.1 - 0.00049 20.2 0.7 0.00059 20.0 0.7 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region FtsL PF04999.13 OEU18159.1 - 0.00054 19.9 0.3 0.00084 19.3 0.3 1.3 1 0 0 1 1 1 1 Cell division protein FtsL EMC3_TMCO1 PF01956.16 OEU18159.1 - 0.0044 16.8 0.5 0.0044 16.8 0.5 1.6 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Ctr PF04145.15 OEU18159.1 - 0.014 16.0 0.2 0.02 15.5 0.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF966 PF06136.13 OEU18159.1 - 0.034 13.9 4.0 0.039 13.7 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Calc_CGRP_IAPP PF00214.19 OEU18159.1 - 0.049 14.0 2.5 0.075 13.4 2.5 1.4 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family YbhQ PF11076.8 OEU18159.1 - 0.066 13.2 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF4692 PF15763.5 OEU18159.1 - 0.079 13.4 0.8 0.098 13.1 0.8 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FAM60A PF15396.6 OEU18159.1 - 0.14 12.1 5.0 0.16 11.9 5.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4083 PF13314.6 OEU18159.1 - 0.15 12.0 3.1 0.34 10.9 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) SID-1_RNA_chan PF13965.6 OEU18159.1 - 0.16 10.4 0.7 0.19 10.1 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 7TM_GPCR_Srx PF10328.9 OEU18159.1 - 0.18 11.4 0.3 0.23 11.1 0.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1635 PF07795.11 OEU18159.1 - 0.18 11.6 4.9 0.23 11.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) EphA2_TM PF14575.6 OEU18159.1 - 0.21 12.5 10.8 8 7.4 10.8 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatD PF13584.6 OEU18159.1 - 0.23 10.2 4.0 0.17 10.6 2.9 1.4 1 1 0 1 1 1 0 Oxygen tolerance DUF4446 PF14584.6 OEU18159.1 - 0.73 9.8 7.6 7.9 6.5 7.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.19 OEU18159.1 - 0.86 7.4 7.3 1.5 6.7 7.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Conotoxin PF02950.17 OEU18159.1 - 1.3 10.1 7.2 1 10.5 1.6 2.4 2 1 0 2 2 2 0 Conotoxin OSTbeta PF15048.6 OEU18159.1 - 1.4 9.0 6.0 2.4 8.3 6.0 1.5 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4834 PF16118.5 OEU18159.1 - 2.1 9.3 14.7 21 6.2 14.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2500 PF10694.9 OEU18159.1 - 5.3 7.6 6.8 0.42 11.1 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) FAM176 PF14851.6 OEU18160.1 - 8.1 6.1 11.0 0.54 9.9 4.1 2.2 1 1 1 2 2 2 0 FAM176 family WRNPLPNID PF15017.6 OEU18160.1 - 9.2 7.2 9.7 1.6 9.7 3.4 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Methyltransf_24 PF13578.6 OEU18162.1 - 2.7e-05 25.1 0.0 6.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MPS-4 PF17523.2 OEU18162.1 - 0.037 14.2 0.2 0.091 12.9 0.2 1.6 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Trypsin PF00089.26 OEU18164.1 - 2.8e-43 148.3 0.5 6.9e-43 147.0 0.5 1.6 1 1 0 1 1 1 1 Trypsin Topoisom_I_N PF02919.15 OEU18166.1 - 1.4e-05 24.8 12.3 0.00012 21.7 0.5 2.2 2 0 0 2 2 2 2 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF3385 PF11865.8 OEU18166.1 - 0.066 13.1 3.1 0.067 13.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) DUF4407 PF14362.6 OEU18166.1 - 0.25 10.6 3.8 0.74 9.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MIF4G_like_2 PF09090.11 OEU18166.1 - 1.5 8.3 10.5 1.6 8.2 5.3 2.5 1 1 0 2 2 2 0 MIF4G like EIIBC-GUT_N PF03612.14 OEU18166.1 - 2 8.1 6.6 6 6.6 2.1 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AdoMet_dc PF02675.15 OEU18167.1 - 6e-21 74.7 0.0 1.3e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Spermine_synth PF01564.17 OEU18167.1 - 3.3e-15 56.0 0.0 6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 OEU18167.1 - 0.0061 17.2 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU18167.1 - 0.0076 17.0 0.7 0.09 13.5 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain GST_N_3 PF13417.6 OEU18168.1 - 4.3e-14 52.7 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU18168.1 - 9.8e-13 48.2 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU18168.1 - 1.2e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU18168.1 - 6.2e-06 26.5 0.0 2.5e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OEU18168.1 - 1.5e-05 25.1 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU18168.1 - 0.0004 20.6 0.0 0.00088 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OEU18168.1 - 0.007 17.1 0.1 0.059 14.1 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 OEU18168.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OEU18168.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin VDE PF07137.11 OEU18169.1 - 2e-78 263.2 2.3 2.7e-78 262.8 2.3 1.2 1 0 0 1 1 1 1 VDE lipocalin domain Lipocalin PF00061.23 OEU18169.1 - 0.0029 17.8 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF762 PF05555.11 OEU18169.1 - 0.17 11.4 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) FAD_binding_3 PF01494.19 OEU18170.1 - 1.7e-16 60.4 0.2 3.7e-07 29.7 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 OEU18170.1 - 4e-06 26.2 1.7 7.6e-06 25.3 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OEU18170.1 - 0.00014 22.0 1.5 0.00029 21.0 0.7 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OEU18170.1 - 0.0015 17.8 0.2 0.0027 17.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OEU18170.1 - 0.0055 16.0 1.8 0.0056 15.9 0.5 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU18170.1 - 0.0055 15.4 1.7 0.0097 14.6 1.7 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OEU18170.1 - 0.0073 15.4 1.0 0.011 14.9 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU18170.1 - 0.035 13.4 3.1 0.055 12.8 3.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OEU18170.1 - 0.037 14.6 0.1 0.072 13.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU18170.1 - 0.59 9.6 5.2 1.3 8.5 1.4 2.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OEU18171.1 - 1.5e-67 228.9 0.0 1.7e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU18171.1 - 2.9e-17 62.6 0.1 5.7e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU18171.1 - 5.1e-09 36.2 0.0 8.6e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU18171.1 - 1e-07 31.5 0.0 8.9e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OEU18171.1 - 2e-06 26.9 0.0 0.0019 17.0 0.0 2.3 2 0 0 2 2 2 2 MCRA family Pyr_redox PF00070.27 OEU18171.1 - 1.5e-05 25.5 0.0 0.00099 19.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU18171.1 - 0.00048 18.9 0.6 0.0011 17.7 0.8 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OEU18171.1 - 0.0009 18.7 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU18171.1 - 0.00096 18.3 0.5 0.0017 17.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 OEU18171.1 - 0.002 16.7 0.1 0.0029 16.1 0.1 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 OEU18171.1 - 0.0071 15.6 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OEU18171.1 - 0.0072 15.6 0.1 0.023 13.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OEU18171.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 OEU18171.1 - 0.051 12.4 0.1 9.3 5.0 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OEU18171.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 OEU18171.1 - 0.077 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain K_oxygenase PF13434.6 OEU18171.1 - 0.094 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 OEU18171.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OEU18171.1 - 0.15 12.0 0.1 0.46 10.4 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AOX PF01786.17 OEU18172.1 - 1.1e-77 260.4 0.1 1.5e-77 260.0 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase EF-hand_1 PF00036.32 OEU18172.1 - 0.00024 20.4 0.1 0.00068 19.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OEU18172.1 - 0.0012 18.3 0.3 0.0026 17.2 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OEU18172.1 - 0.0067 16.8 0.2 0.015 15.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU18172.1 - 0.067 13.2 0.1 0.22 11.6 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain HATPase_c PF02518.26 OEU18173.1 - 5.3e-24 84.9 0.9 5.3e-24 84.9 0.9 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OEU18173.1 - 7.4e-22 77.6 0.0 1.6e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OEU18173.1 - 4.1e-08 33.1 0.3 5e-07 29.7 0.0 2.7 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OEU18173.1 - 0.0013 18.5 0.1 0.0032 17.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 OEU18173.1 - 0.0032 17.4 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Rubis-subs-bind PF09273.11 OEU18174.1 - 1e-20 74.8 0.0 2.1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OEU18174.1 - 1.1e-12 48.7 0.0 2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Glyco_hydro_1 PF00232.18 OEU18175.1 - 1.2e-166 554.6 3.7 1.5e-166 554.4 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SUIM_assoc PF16619.5 OEU18176.1 - 0.0035 17.4 0.5 1.6 8.9 0.2 2.3 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Acyl-CoA_dh_1 PF00441.24 OEU18177.1 - 4.1e-37 127.7 0.4 6.2e-37 127.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OEU18177.1 - 4e-28 98.3 0.0 7.9e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OEU18177.1 - 9.6e-21 73.8 0.1 2.1e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OEU18177.1 - 4.2e-16 59.4 0.0 7.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SR-25 PF10500.9 OEU18177.1 - 2 8.0 7.2 3 7.4 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAD_binding_8 PF08022.12 OEU18178.1 - 4.4e-12 46.1 0.1 3.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 OEU18178.1 - 6.5e-09 36.1 6.5 4.1e-06 27.0 0.0 3.5 4 0 0 4 4 4 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OEU18178.1 - 1.1e-07 32.0 8.6 1.1e-07 32.0 8.6 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 OEU18178.1 - 0.17 12.6 0.0 4.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Hydrolase_3 PF08282.12 OEU18179.1 - 1.8e-49 168.8 5.1 1.2e-47 162.8 5.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OEU18179.1 - 3.3e-16 59.6 0.3 1.1e-07 31.7 0.1 2.3 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 OEU18179.1 - 4.5e-08 33.6 1.0 0.0035 17.7 0.1 3.8 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OEU18179.1 - 5e-06 26.7 1.8 0.35 10.9 0.0 3.9 3 2 1 4 4 4 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU18179.1 - 6.1e-05 23.5 0.6 0.77 10.1 0.0 3.5 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OEU18179.1 - 0.002 18.2 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AIRC PF00731.20 OEU18179.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 AIR carboxylase DUF460 PF04312.13 OEU18179.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) GDP_Man_Dehyd PF16363.5 OEU18180.1 - 7.3e-54 183.4 0.0 8.9e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU18180.1 - 1.5e-47 162.1 0.0 1.9e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU18180.1 - 6.2e-15 54.9 0.0 1.6e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU18180.1 - 3.6e-14 52.6 0.0 4.5e-13 49.0 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OEU18180.1 - 2.6e-08 33.4 0.0 4.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 OEU18180.1 - 8.9e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OEU18180.1 - 1.9e-05 23.9 0.0 4.6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OEU18180.1 - 0.0022 17.5 0.0 0.0068 15.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OEU18180.1 - 0.0076 16.2 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF3494 PF11999.8 OEU18181.1 - 3.4e-55 186.9 15.8 4.5e-55 186.5 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) FecR PF04773.13 OEU18181.1 - 0.069 13.8 0.3 0.18 12.4 0.3 1.7 1 0 0 1 1 1 0 FecR protein Exo_endo_phos PF03372.23 OEU18182.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 OEU18182.1 - 0.00017 21.2 0.1 0.0012 18.4 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU18182.1 - 0.0088 16.7 1.7 0.033 14.9 1.7 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 OEU18182.1 - 0.024 14.9 0.0 0.18 12.1 0.0 2.6 1 0 0 1 1 1 0 Transposase PT PF04886.12 OEU18184.1 - 5.7e-07 29.0 51.0 2.1 7.9 10.2 3.5 1 1 1 2 2 2 2 PT repeat CCDC53 PF10152.9 OEU18184.1 - 0.047 14.1 1.3 0.13 12.6 1.3 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Abi_HHR PF07815.14 OEU18185.1 - 0.033 14.3 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Abl-interactor HHR Hydrolase_4 PF12146.8 OEU18185.1 - 0.035 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MatE PF01554.18 OEU18187.1 - 2.5e-23 82.5 25.3 1.2e-14 54.2 4.0 2.6 3 0 0 3 3 3 2 MatE PDZ_6 PF17820.1 OEU18187.1 - 0.023 14.6 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 PDZ domain TMEM154 PF15102.6 OEU18187.1 - 0.15 12.0 3.5 13 5.7 1.1 3.1 2 1 1 3 3 3 0 TMEM154 protein family 40S_S4_C PF16121.5 OEU18187.1 - 0.16 11.7 0.2 0.33 10.6 0.2 1.6 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus DUF4889 PF16230.5 OEU18188.1 - 0.14 12.4 1.5 2.2 8.6 1.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4889) SMP_LBD PF17047.5 OEU18189.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain Type2_restr_D3 PF16902.5 OEU18190.1 - 0.036 14.0 1.4 0.18 11.7 0.3 2.7 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Activator_LAG-3 PF11498.8 OEU18190.1 - 1.9 7.4 10.6 3.3 6.6 10.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Trypan_PARP PF05887.11 OEU18191.1 - 4.5 7.2 5.5 12 5.9 5.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.22 OEU18192.1 - 0.039 13.2 3.2 0.063 12.5 1.6 2.1 1 1 1 2 2 2 0 ZIP Zinc transporter FliJ PF02050.16 OEU18192.1 - 0.97 9.7 6.4 2.3 8.5 6.4 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein SUR7 PF06687.12 OEU18193.1 - 0.092 12.4 1.7 0.14 11.7 1.7 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF285 PF03382.14 OEU18194.1 - 1.2e-61 205.8 24.3 8.8e-35 119.1 10.8 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 DUF3889 PF13028.6 OEU18194.1 - 0.084 12.8 0.0 4.8 7.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3889) HSF_DNA-bind PF00447.17 OEU18195.1 - 3.9e-13 49.8 0.1 4.5e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1430 PF07242.11 OEU18195.1 - 0.0041 17.3 0.3 0.006 16.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1430) PIP5K PF01504.18 OEU18195.1 - 0.022 14.0 0.2 0.022 14.0 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase LEF-8 PF04941.12 OEU18195.1 - 0.13 10.5 0.0 0.15 10.2 0.0 1.0 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) HA PF03457.14 OEU18196.1 - 6.9e-16 58.3 1.8 7.2e-09 35.8 0.4 2.9 2 0 0 2 2 2 2 Helicase associated domain SR-25 PF10500.9 OEU18196.1 - 0.029 14.0 0.9 0.029 14.0 0.9 5.3 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein K_channel_TID PF07941.11 OEU18196.1 - 1.7 9.1 4.4 0.71 10.4 0.9 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Histidinol_dh PF00815.20 OEU18197.1 - 0.18 10.8 4.8 0.2 10.6 4.3 1.3 1 1 0 1 1 1 0 Histidinol dehydrogenase Peptidase_S10 PF00450.22 OEU18202.1 - 6e-77 259.8 0.1 1.2e-76 258.8 0.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Shisa PF13908.6 OEU18203.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Corona_S2 PF01601.16 OEU18203.1 - 0.56 8.6 5.6 0.81 8.1 5.6 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Insulin_TMD PF17870.1 OEU18203.1 - 0.73 9.9 3.3 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment SCIMP PF15050.6 OEU18203.1 - 1.2 9.6 5.0 2.9 8.3 2.9 2.2 2 0 0 2 2 2 0 SCIMP protein WBP-1 PF11669.8 OEU18203.1 - 4 8.1 8.1 35 5.1 7.4 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 TPR_2 PF07719.17 OEU18204.1 - 0.00026 20.9 1.2 0.064 13.4 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU18204.1 - 0.0045 17.2 3.0 0.52 10.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU18204.1 - 0.024 14.8 1.5 0.55 10.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU18204.1 - 0.12 12.2 4.7 1.9 8.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU18204.1 - 0.18 11.7 1.5 68 3.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Striatin PF08232.12 OEU18204.1 - 0.3 11.7 7.1 0.29 11.7 0.7 2.3 2 0 0 2 2 2 0 Striatin family Cwf_Cwc_15 PF04889.12 OEU18204.1 - 1.6 8.4 11.3 3.1 7.5 5.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SUIM_assoc PF16619.5 OEU18204.1 - 2.1 8.5 18.0 0.3 11.2 3.2 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Nucleotid_trans PF03407.16 OEU18205.1 - 4.7e-14 52.9 2.6 1.9e-13 50.9 0.2 2.2 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase SR-25 PF10500.9 OEU18205.1 - 5.6 6.5 6.4 1.5 8.4 3.3 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1499 PF07386.11 OEU18206.1 - 1.4e-20 74.0 0.0 2.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Pro_isomerase PF00160.21 OEU18208.1 - 6.6e-45 153.2 0.1 7.7e-45 153.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sigma_reg_N PF13800.6 OEU18210.1 - 0.029 14.7 0.2 0.12 12.6 0.2 2.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Sulfotransfer_3 PF13469.6 OEU18210.1 - 0.03 14.7 0.0 2.6 8.4 0.0 2.6 1 1 0 1 1 1 0 Sulfotransferase family CW_binding_1 PF01473.20 OEU18210.1 - 0.38 11.2 6.0 1.4 9.4 6.0 2.1 1 0 0 1 1 1 0 Putative cell wall binding repeat SID-1_RNA_chan PF13965.6 OEU18210.1 - 0.48 8.8 8.7 0.043 12.2 3.2 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SARAF PF06682.12 OEU18210.1 - 3.2 7.3 10.7 0.11 12.1 0.9 2.9 2 2 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4519 PF15012.6 OEU18210.1 - 5 7.4 7.7 25 5.1 7.7 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) MASE3 PF17159.4 OEU18211.1 - 0.0079 15.8 6.1 0.008 15.8 0.7 2.6 3 0 0 3 3 3 1 Membrane-associated sensor domain DUF2207 PF09972.9 OEU18211.1 - 0.26 10.0 5.4 6.3 5.4 1.4 2.9 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF1980 PF09323.10 OEU18211.1 - 0.49 10.3 3.9 6.7 6.6 1.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) MLANA PF14991.6 OEU18211.1 - 2.4 8.4 0.0 2.4 8.4 0.0 2.7 3 1 0 3 3 3 0 Protein melan-A STALD PF18185.1 OEU18212.1 - 0.0031 16.9 0.6 0.0048 16.3 0.6 1.3 1 0 0 1 1 1 1 Sir2- and TIR-associating SLOG family PAP_PilO PF06864.12 OEU18212.1 - 0.025 13.4 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Presenilin PF01080.17 OEU18212.1 - 0.029 13.1 6.5 0.034 12.9 6.5 1.0 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 OEU18212.1 - 0.031 13.9 4.9 0.045 13.4 4.9 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CD20 PF04103.15 OEU18212.1 - 0.086 12.9 0.1 4.5 7.3 0.0 2.1 1 1 1 2 2 2 0 CD20-like family DUF4813 PF16072.5 OEU18212.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) LapA_dom PF06305.11 OEU18212.1 - 0.35 10.7 0.6 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain UPF0560 PF10577.9 OEU18212.1 - 2.1 6.7 5.9 2.6 6.4 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 XRN_M PF17846.1 OEU18212.1 - 5.6 5.8 8.6 6.7 5.5 8.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain HA PF03457.14 OEU18216.1 - 1.8e-43 146.7 3.1 4.9e-17 62.0 0.1 4.2 3 1 0 3 3 3 3 Helicase associated domain Gag_p10 PF02337.17 OEU18216.1 - 0.0004 20.3 1.2 6.1 6.9 0.1 3.2 3 0 0 3 3 3 3 Retroviral GAG p10 protein Nkap_C PF06047.11 OEU18216.1 - 0.0095 16.0 0.1 0.46 10.6 0.1 2.4 1 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain ACAS_N PF16177.5 OEU18216.1 - 0.066 13.1 0.2 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Atu4866 PF11512.8 OEU18216.1 - 0.11 12.9 0.0 8.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 Silic_transp PF03842.13 OEU18218.1 - 8.4e-104 347.7 25.9 9.9e-104 347.4 25.9 1.1 1 0 0 1 1 1 1 Silicon transporter FACT-Spt16_Nlob PF14826.6 OEU18218.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain ANAPC5 PF12862.7 OEU18220.1 - 0.014 15.5 0.2 0.027 14.5 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 CDH1_2_SANT_HL1 PF18375.1 OEU18220.1 - 0.088 13.5 1.2 0.59 10.8 0.0 2.6 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 DUF1249 PF06853.12 OEU18220.1 - 0.099 12.7 1.4 0.12 12.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1249) DUF2992 PF11208.8 OEU18220.1 - 0.8 9.9 5.1 0.41 10.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) DGF-1_C PF11040.8 OEU18221.1 - 3.2 7.8 8.1 5.5 7.1 0.1 2.9 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CIA30 PF08547.12 OEU18222.1 - 3.3e-13 50.0 0.2 7.2e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) 7tm_3 PF00003.22 OEU18225.1 - 5.2e-36 124.6 22.7 7.5e-36 124.0 22.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR OpuAC PF04069.12 OEU18225.1 - 0.057 13.0 0.1 25 4.3 0.0 3.2 3 0 0 3 3 3 0 Substrate binding domain of ABC-type glycine betaine transport system Cyanate_lyase PF02560.14 OEU18226.1 - 2.4e-25 88.1 0.0 3.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 OEU18226.1 - 1.5e-05 24.9 0.2 2.9e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix SAP130_C PF16014.5 OEU18226.1 - 0.08 12.0 1.3 0.1 11.7 1.3 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus SOGA PF11365.8 OEU18229.1 - 0.0072 17.4 4.8 0.0072 17.4 4.8 16.9 9 8 8 19 19 19 4 Protein SOGA zf-C3HC4_3 PF13920.6 OEU18230.1 - 9.1e-11 41.5 19.5 2.1e-10 40.3 19.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU18230.1 - 6.9e-06 25.8 17.5 1.9e-05 24.4 17.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Dmrt1 PF12374.8 OEU18230.1 - 1.8 9.1 8.2 0.78 10.2 2.3 2.7 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 zf-C3HC4_4 PF15227.6 OEU18230.1 - 5.9 7.1 16.0 23 5.2 16.0 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3446 PF11928.8 OEU18230.1 - 6.3 7.2 20.4 0.19 12.1 2.2 3.5 4 0 0 4 4 4 0 Early growth response N-terminal domain zf-RING_UBOX PF13445.6 OEU18230.1 - 7.7 6.6 18.3 20 5.3 12.7 2.7 2 0 0 2 2 2 0 RING-type zinc-finger OrfB_Zn_ribbon PF07282.11 OEU18231.1 - 0.036 14.0 0.2 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PatG_D PF18047.1 OEU18231.1 - 0.054 13.9 1.1 3.1 8.3 0.1 3.0 1 1 1 2 2 2 0 PatG Domain DUF3517 PF12030.8 OEU18231.1 - 0.057 12.3 1.8 2.9 6.7 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3517) LRAT PF04970.13 OEU18231.1 - 0.089 13.1 0.1 0.41 10.9 0.1 2.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase ATP-synt PF00231.19 OEU18232.1 - 3.9e-76 256.5 3.4 5.2e-76 256.0 3.4 1.2 1 0 0 1 1 1 1 ATP synthase Ribosomal_L37ae PF01780.19 OEU18232.1 - 0.024 14.7 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF1128 PF06569.11 OEU18232.1 - 0.25 11.4 1.8 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) ALMT PF11744.8 OEU18233.1 - 0.13 11.1 8.1 0.16 10.8 8.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 OEU18234.1 - 0.0049 16.1 5.5 0.0054 16.0 5.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.16 OEU18234.1 - 0.022 14.9 2.8 0.027 14.5 2.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PNISR PF15996.5 OEU18234.1 - 0.03 14.6 13.6 0.044 14.1 13.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SLC12 PF03522.15 OEU18234.1 - 0.042 12.9 6.2 0.047 12.7 6.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Calc_CGRP_IAPP PF00214.19 OEU18234.1 - 0.085 13.2 2.9 0.16 12.4 2.9 1.5 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family SAPS PF04499.15 OEU18234.1 - 0.1 11.4 4.2 0.11 11.3 4.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 OEU18234.1 - 0.27 9.9 8.4 0.31 9.8 8.4 1.0 1 0 0 1 1 1 0 Raftlin V_ATPase_I PF01496.19 OEU18234.1 - 0.89 7.4 3.6 0.86 7.4 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 OEU18234.1 - 1.2 9.5 15.2 1.8 9.0 15.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RAP1 PF07218.11 OEU18234.1 - 1.7 6.8 16.6 1.9 6.7 16.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RR_TM4-6 PF06459.12 OEU18234.1 - 2.1 8.1 15.5 2.6 7.8 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 OEU18234.1 - 2.4 7.9 16.1 4 7.2 16.1 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein Vfa1 PF08432.10 OEU18234.1 - 3.8 7.8 20.6 6 7.2 20.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Band_3_cyto PF07565.13 OEU18234.1 - 4.2 7.1 8.8 4.9 6.9 8.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.12 OEU18234.1 - 4.3 6.2 9.8 5 6.0 9.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Paf1 PF03985.13 OEU18234.1 - 5 6.0 14.8 6.5 5.6 14.8 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 OEU18234.1 - 8.7 4.5 17.4 10 4.3 17.4 1.0 1 0 0 1 1 1 0 CDC45-like protein PT PF04886.12 OEU18235.1 - 3.5e-09 36.0 54.5 0.00058 19.3 17.9 3.5 1 1 1 2 2 2 2 PT repeat BUD22 PF09073.10 OEU18235.1 - 0.16 11.3 12.0 0.34 10.2 12.0 1.5 1 0 0 1 1 1 0 BUD22 DUF1681 PF07933.14 OEU18236.1 - 1.8e-25 89.3 0.0 2.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Nop14 PF04147.12 OEU18237.1 - 0.4 8.8 25.2 0.32 9.1 15.2 2.5 2 0 0 2 2 2 0 Nop14-like family Orf78 PF06024.12 OEU18238.1 - 0.0065 16.8 0.2 0.0065 16.8 0.2 3.0 3 0 0 3 3 3 1 Orf78 (ac78) DUF2973 PF11189.8 OEU18238.1 - 0.11 12.7 7.4 6.8 6.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) Macoilin PF09726.9 OEU18238.1 - 0.23 10.0 11.4 0.042 12.4 8.2 1.4 2 0 0 2 2 2 0 Macoilin family Apt1 PF10351.9 OEU18238.1 - 0.62 8.9 11.0 0.96 8.2 11.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ctr PF04145.15 OEU18238.1 - 8.7 7.0 7.5 50 4.5 6.9 2.5 2 1 0 2 2 2 0 Ctr copper transporter family DHH PF01368.20 OEU18238.1 - 8.9 6.6 14.4 2.8 8.2 1.8 3.1 1 1 0 3 3 3 0 DHH family 2OG-FeII_Oxy_3 PF13640.6 OEU18239.1 - 7e-16 58.9 0.0 2.6e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pex14_N PF04695.13 OEU18240.1 - 0.38 11.4 0.0 0.38 11.4 0.0 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HSF_DNA-bind PF00447.17 OEU18241.1 - 2e-12 47.5 0.1 2.1e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding GCV_T PF01571.21 OEU18242.1 - 8e-75 251.5 0.0 9.9e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OEU18242.1 - 3.8e-07 29.9 0.0 7.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HSF_DNA-bind PF00447.17 OEU18244.1 - 2.4e-15 56.9 1.4 4.3e-15 56.1 1.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding AID PF18767.1 OEU18244.1 - 0.088 12.8 0.1 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 Activation induced deaminase HSF_DNA-bind PF00447.17 OEU18245.1 - 1.2e-11 45.1 1.0 2.9e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding F-box PF00646.33 OEU18246.1 - 4.5e-05 23.2 0.6 0.00015 21.5 0.0 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OEU18246.1 - 0.00036 20.4 0.1 0.0011 18.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OEU18246.1 - 0.008 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 OEU18246.1 - 0.043 14.3 8.8 0.065 13.7 0.3 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) NUC153 PF08159.12 OEU18248.1 - 0.14 12.0 0.8 0.31 10.9 0.8 1.6 1 0 0 1 1 1 0 NUC153 domain JAB PF01398.21 OEU18249.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cwf_Cwc_15 PF04889.12 OEU18250.1 - 0.037 13.8 3.1 0.062 13.0 3.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UPF0370 PF13980.6 OEU18250.1 - 0.094 12.8 4.5 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) SURF1 PF02104.15 OEU18251.1 - 1.3e-26 93.9 0.0 2.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 SURF1 family SSF PF00474.17 OEU18252.1 - 3.1e-16 59.3 33.7 3.1e-16 59.3 33.7 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family Ac76 PF05814.11 OEU18252.1 - 5.1 7.2 6.2 6 6.9 2.4 2.7 2 0 0 2 2 2 0 Orf76 (Ac76) FmdA_AmdA PF03069.15 OEU18253.1 - 1e-158 528.1 0.0 1.6e-158 527.5 0.0 1.3 1 1 0 1 1 1 1 Acetamidase/Formamidase family APH PF01636.23 OEU18254.1 - 4.8e-12 46.3 0.0 1.2e-11 45.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OEU18254.1 - 5.1e-08 32.8 0.0 9.5e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OEU18254.1 - 0.0047 15.8 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 OEU18254.1 - 0.043 13.1 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase Folate_rec PF03024.14 OEU18255.1 - 9.1e-36 123.3 13.6 3.9e-30 105.0 13.4 2.2 2 0 0 2 2 2 2 Folate receptor family ETRAMP PF09716.10 OEU18255.1 - 0.0027 17.7 0.1 0.0049 16.9 0.1 1.9 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) EF-hand_1 PF00036.32 OEU18256.1 - 0.01 15.3 0.1 0.029 13.9 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OEU18256.1 - 0.018 14.9 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 OEU18256.1 - 0.036 13.6 1.4 0.057 12.9 0.1 2.1 2 0 0 2 2 2 0 EF hand SR-25 PF10500.9 OEU18256.1 - 1.6 8.3 6.6 2.5 7.6 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myc_N PF01056.18 OEU18257.1 - 0.0085 16.0 3.7 0.0085 16.0 3.7 2.4 2 0 0 2 2 2 1 Myc amino-terminal region DUF4379 PF14311.6 OEU18257.1 - 0.016 15.5 8.7 0.38 11.2 0.1 3.2 3 0 0 3 3 3 0 Probable Zinc-ribbon domain zf-C2H2_4 PF13894.6 OEU18257.1 - 0.023 15.5 9.4 1.2 10.1 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 OEU18257.1 - 0.66 10.4 4.6 7.2 7.2 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribosomal_60s PF00428.19 OEU18257.1 - 0.77 10.4 9.5 0.8 10.3 6.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM163 PF15069.6 OEU18257.1 - 1.4 9.3 11.9 4.3 7.8 0.2 3.0 3 0 0 3 3 3 0 FAM163 family TMEM171 PF15471.6 OEU18258.1 - 0.53 9.2 6.3 0.73 8.8 0.4 2.8 2 0 0 2 2 2 0 Transmembrane protein family 171 LytR_C PF13399.6 OEU18258.1 - 5.9 8.0 6.5 14 6.8 1.5 2.8 1 1 1 2 2 2 0 LytR cell envelope-related transcriptional attenuator LRR_4 PF12799.7 OEU18259.1 - 0.01 16.2 19.6 0.068 13.6 3.1 6.6 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU18259.1 - 0.41 11.4 4.2 7.9 7.5 0.3 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat Metallophos PF00149.28 OEU18260.1 - 6.5e-12 46.4 2.8 1.3e-11 45.4 0.5 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Ada3 PF10198.9 OEU18260.1 - 7.2 6.8 11.4 0.96 9.6 0.4 3.5 2 1 1 3 3 3 0 Histone acetyltransferases subunit 3 HA PF03457.14 OEU18261.1 - 2.5e-72 239.1 22.1 2.3e-19 69.5 0.1 5.1 5 0 0 5 5 5 5 Helicase associated domain ATP_transf PF09830.9 OEU18262.1 - 0.068 13.3 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 ATP adenylyltransferase CN_hydrolase PF00795.22 OEU18263.1 - 8.2e-27 94.2 0.0 1.2e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 OEU18263.1 - 1.4e-20 73.4 0.0 3.5e-10 39.4 0.0 3.5 1 1 0 2 2 2 2 NAD synthase NPR3 PF03666.13 OEU18265.1 - 0.12 11.2 7.5 0.2 10.4 7.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2407_C PF13373.6 OEU18265.1 - 1.3 9.2 4.9 2.3 8.4 2.7 2.4 1 1 1 2 2 2 0 DUF2407 C-terminal domain RCC1_2 PF13540.6 OEU18266.1 - 6.8e-14 51.2 4.7 7.1e-11 41.6 0.1 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OEU18266.1 - 2.2e-12 47.4 6.0 1.2e-08 35.4 0.2 2.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 OEU18267.1 - 2.1e-75 254.1 0.0 2.3e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Thioredoxin_4 PF13462.6 OEU18270.1 - 1e-08 35.6 0.0 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin DSBA PF01323.20 OEU18270.1 - 0.064 13.0 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Myb_DNA-binding PF00249.31 OEU18273.1 - 3e-18 65.7 1.2 8e-09 35.6 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU18273.1 - 2.7e-08 33.6 1.6 0.00018 21.3 0.1 3.8 3 1 1 4 4 4 2 Myb DNA-binding like Linker_histone PF00538.19 OEU18273.1 - 1.1e-05 25.7 0.3 1.1e-05 25.7 0.3 2.6 2 0 0 2 2 2 1 linker histone H1 and H5 family BRK PF07533.16 OEU18273.1 - 0.0018 17.8 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 2 BRK domain RbsD_FucU PF05025.13 OEU18273.1 - 0.029 14.8 2.3 0.57 10.6 0.1 2.9 3 0 0 3 3 3 0 RbsD / FucU transport protein family ChuX_HutX PF06228.13 OEU18274.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX DUF3246 PF11596.8 OEU18274.1 - 0.25 10.7 4.0 0.68 9.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) RskA PF10099.9 OEU18275.1 - 0.13 12.5 2.5 13 6.1 2.5 3.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CD20 PF04103.15 OEU18275.1 - 0.4 10.7 4.4 0.55 10.3 0.1 3.2 3 1 0 3 3 3 0 CD20-like family FleQ PF06490.11 OEU18275.1 - 4.2 7.8 10.0 0.18 12.2 0.4 3.7 3 1 1 4 4 4 0 Flagellar regulatory protein FleQ GHMP_kinases_N PF00288.26 OEU18275.1 - 5.9 7.2 0.0 5.9 7.2 0.0 3.9 4 0 0 4 4 4 0 GHMP kinases N terminal domain ODV-E18 PF10717.9 OEU18276.1 - 0.0051 16.6 1.8 0.0051 16.6 1.8 1.6 1 1 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Imm17 PF15562.6 OEU18276.1 - 0.071 13.0 0.8 0.15 12.0 0.8 1.5 1 0 0 1 1 1 0 Immunity protein 17 DUF5383 PF17355.2 OEU18276.1 - 0.12 12.8 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF3836 PF12930.7 OEU18276.1 - 0.75 9.6 2.7 1.2 8.9 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF3836) EF-hand_6 PF13405.6 OEU18277.1 - 4e-12 45.0 0.1 1.6e-06 27.5 0.1 3.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU18277.1 - 5.5e-09 36.3 0.0 6.4e-08 32.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU18277.1 - 1e-08 34.1 0.1 1.4e-05 24.3 0.0 3.5 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OEU18277.1 - 4.5e-08 32.8 2.4 2.6e-06 27.2 0.2 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU18277.1 - 5.5e-06 25.6 0.9 7e-05 22.1 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 OEU18277.1 - 0.0028 18.0 0.0 0.04 14.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 OEU18277.1 - 0.0081 16.2 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand DUF3490 PF11995.8 OEU18277.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Glyco_transf_25 PF01755.17 OEU18278.1 - 0.0001 22.2 0.3 0.032 14.1 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3446 PF11928.8 OEU18278.1 - 4 7.8 26.2 0.72 10.2 4.2 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain ABC2_membrane PF01061.24 OEU18279.1 - 1.3e-29 103.1 22.7 1.3e-29 103.1 22.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OEU18279.1 - 1.3e-27 97.0 0.0 2.5e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OEU18279.1 - 7.6e-07 28.6 19.6 7.6e-07 28.6 19.6 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OEU18279.1 - 2.3e-06 27.7 1.6 0.0025 17.7 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU18279.1 - 0.00019 21.4 0.1 0.00041 20.3 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 OEU18279.1 - 0.00066 19.2 1.1 0.14 11.5 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU18279.1 - 0.0073 16.7 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OEU18279.1 - 0.079 13.4 2.8 0.48 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OEU18279.1 - 0.085 12.9 0.2 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Glutaredoxin PF00462.24 OEU18281.1 - 1.1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OEU18281.1 - 0.00014 22.3 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DRMBL PF07522.14 OEU18281.1 - 0.00037 20.6 0.0 0.00043 20.5 0.0 1.1 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase GST_N_3 PF13417.6 OEU18281.1 - 0.00075 19.9 0.0 0.0016 18.8 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 OEU18281.1 - 0.0053 17.1 0.0 0.0073 16.7 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 OEU18281.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain OTT_1508_deam PF14441.6 OEU18281.1 - 0.022 14.7 0.1 0.036 14.1 0.1 1.4 1 1 0 1 1 1 0 OTT_1508-like deaminase Redoxin PF08534.10 OEU18281.1 - 0.053 13.2 0.0 0.09 12.5 0.0 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.6 OEU18281.1 - 0.082 13.1 0.7 1.7 8.8 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 OEU18281.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein zf-Di19 PF05605.12 OEU18281.1 - 0.13 12.6 0.2 0.21 11.9 0.1 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF4479 PF14794.6 OEU18282.1 - 0.082 12.8 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) MvaI_BcnI PF15515.6 OEU18283.1 - 0.018 14.9 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family Tmemb_9 PF05434.11 OEU18283.1 - 0.018 14.9 0.5 0.023 14.6 0.5 1.3 1 0 0 1 1 1 0 TMEM9 Ank_4 PF13637.6 OEU18284.1 - 3.3e-05 24.4 0.1 0.17 12.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU18284.1 - 0.00072 20.1 0.0 0.011 16.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Presenilin PF01080.17 OEU18285.1 - 0.029 13.1 4.2 0.038 12.8 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF2615 PF11027.8 OEU18285.1 - 0.055 13.6 2.3 7.9 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Zip PF02535.22 OEU18285.1 - 4.2 6.5 4.8 1.1 8.4 1.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter CTP_transf_1 PF01148.20 OEU18287.1 - 7.9e-65 219.3 15.9 1.1e-64 218.7 15.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family HSF_DNA-bind PF00447.17 OEU18288.1 - 1.5e-15 57.6 0.2 3.5e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 OEU18288.1 - 0.046 14.2 0.8 0.1 13.1 0.1 1.9 2 0 0 2 2 2 0 Ets-domain Herpes_LP PF03363.13 OEU18288.1 - 0.07 12.9 0.2 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus leader protein IRK_N PF08466.10 OEU18288.1 - 1.1 9.5 4.8 1.4 9.1 2.8 2.3 1 1 1 2 2 2 0 Inward rectifier potassium channel N-terminal RskA PF10099.9 OEU18291.1 - 0.0009 19.6 0.0 0.0012 19.2 0.0 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1668 PF07893.13 OEU18291.1 - 0.078 12.3 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) PRIMA1 PF16101.5 OEU18291.1 - 0.56 10.3 6.2 1.2 9.1 6.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cytochrom_D1 PF02239.16 OEU18292.1 - 0.006 15.2 1.5 0.067 11.7 0.2 2.7 3 0 0 3 3 3 1 Cytochrome D1 heme domain DUF4883 PF16224.5 OEU18292.1 - 0.0068 16.6 1.7 0.011 16.0 0.7 1.8 2 0 0 2 2 2 1 DOmain of unknown function (DUF4883) Cytidylate_kin PF02224.18 OEU18292.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Helicase_C_2 PF13307.6 OEU18293.1 - 1.4e-44 152.3 0.0 5.8e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OEU18293.1 - 1.9e-30 105.8 0.2 4.6e-22 78.5 0.0 2.7 2 0 0 2 2 2 2 DEAD_2 PDZ PF00595.24 OEU18293.1 - 1e-10 41.8 0.0 2.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU18293.1 - 0.00089 19.1 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU18293.1 - 0.0033 17.7 0.0 0.0089 16.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tetraspanin PF00335.20 OEU18295.1 - 2 8.0 12.4 97 2.6 12.4 2.2 1 1 0 1 1 1 0 Tetraspanin family BTB_2 PF02214.22 OEU18296.1 - 2.1e-15 56.8 0.1 5.6e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 OEU18296.1 - 6.8e-07 29.3 0.0 2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Cpn10 PF00166.21 OEU18297.1 - 1.4e-22 79.5 0.0 1.5e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MscS_TM PF12794.7 OEU18298.1 - 5.9 5.7 4.1 16 4.2 4.1 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2237 PF09996.9 OEU18299.1 - 6.8e-12 45.4 3.1 9.4e-12 44.9 3.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) MORN PF02493.20 OEU18301.1 - 0.0011 18.7 0.7 0.0011 18.7 0.7 5.0 6 0 0 6 6 6 2 MORN repeat FKBP_C PF00254.28 OEU18302.1 - 4.1e-20 71.9 0.0 7e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 OEU18302.1 - 2.3e-07 31.7 0.1 9.5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ERp29 PF07749.12 OEU18302.1 - 0.0038 18.1 0.2 0.0062 17.4 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4574 PF15141.6 OEU18302.1 - 0.26 11.2 0.6 11 6.0 0.3 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 FKBP_C PF00254.28 OEU18303.1 - 4.2e-13 49.4 0.0 5.8e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 OEU18303.1 - 0.055 14.4 0.0 0.09 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF285 PF03382.14 OEU18304.1 - 1.8e-108 357.0 104.7 4e-23 81.5 15.8 6.2 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 Phage_tail_2 PF06199.11 OEU18304.1 - 1.6e-09 37.9 13.6 3.4 7.8 0.1 9.1 1 1 8 10 10 10 3 Phage tail tube protein NAD_binding_5 PF07994.12 OEU18304.1 - 0.011 15.2 3.0 11 5.3 0.0 4.3 3 1 1 4 4 4 0 Myo-inositol-1-phosphate synthase Cellsynth_D PF03500.13 OEU18304.1 - 0.014 15.3 1.2 6.3 6.7 0.0 3.7 2 1 2 4 4 4 0 Cellulose synthase subunit D Pro_sub2 PF18513.1 OEU18304.1 - 0.11 12.7 7.5 6.7 7.0 0.1 5.1 4 3 3 7 7 7 0 Prodomain subtilisin 2 YccV-like PF08755.11 OEU18304.1 - 0.21 12.1 1.1 8.9 6.9 0.0 4.0 3 1 1 4 4 4 0 Hemimethylated DNA-binding protein YccV like CactinC_cactus PF09732.9 OEU18304.1 - 0.3 11.0 12.4 8 6.4 0.0 6.8 2 1 4 8 8 8 0 Cactus-binding C-terminus of cactin protein SgrT PF15894.5 OEU18304.1 - 0.92 9.5 23.3 37 4.4 0.0 10.4 12 1 1 13 13 13 0 Inhibitor of glucose uptake transporter SgrT FTH PF01827.27 OEU18304.1 - 2.5 7.9 8.1 0.83 9.4 0.2 3.3 3 1 0 4 4 4 0 FTH domain ABC1 PF03109.16 OEU18306.1 - 4.1e-13 49.6 0.0 7.6e-12 45.4 0.0 2.4 1 1 0 1 1 1 1 ABC1 family PBP1_TM PF14812.6 OEU18306.1 - 0.42 11.0 9.9 0.89 10.0 0.1 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cu-oxidase_2 PF07731.14 OEU18307.1 - 4.2e-17 62.2 1.8 2.9e-14 53.0 1.5 2.7 2 0 0 2 2 2 2 Multicopper oxidase Acid_PPase PF12689.7 OEU18307.1 - 4.5e-16 59.2 0.4 1.8e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 Acid Phosphatase Cu-oxidase PF00394.22 OEU18307.1 - 2.9e-08 34.0 0.0 1.4e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OEU18307.1 - 6.5e-06 26.2 0.3 0.00024 21.1 0.1 2.9 2 0 0 2 2 2 1 Multicopper oxidase TRAP_alpha PF03896.16 OEU18307.1 - 0.0034 16.6 6.3 0.028 13.6 5.0 2.3 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 OEU18307.1 - 0.017 13.4 2.4 0.023 13.0 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OEU18307.1 - 0.02 13.0 5.0 0.028 12.5 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 OEU18307.1 - 0.16 11.4 5.1 0.28 10.6 5.1 1.3 1 0 0 1 1 1 0 SDA1 Osteopontin PF00865.18 OEU18307.1 - 0.18 11.2 17.4 0.46 9.9 17.4 1.6 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.14 OEU18307.1 - 2.4 6.3 5.2 3.6 5.7 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 OEU18308.1 - 0.028 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain YL1 PF05764.13 OEU18309.1 - 6.6e-05 23.1 4.4 0.072 13.2 0.0 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Polysacc_synt PF01943.17 OEU18309.1 - 0.019 14.4 2.9 0.027 13.9 2.9 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Orai-1 PF07856.12 OEU18309.1 - 0.035 13.8 8.1 0.046 13.4 0.1 2.3 1 1 0 2 2 2 0 Mediator of CRAC channel activity DUF4274 PF14096.6 OEU18309.1 - 0.18 11.8 2.8 0.47 10.4 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DUF2298 PF10060.9 OEU18309.1 - 0.19 10.4 5.1 3.1 6.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized membrane protein (DUF2298) TMEM208_SND2 PF05620.11 OEU18309.1 - 0.21 11.3 2.3 0.62 9.8 0.0 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 POX PF07526.11 OEU18309.1 - 1.1 9.8 5.2 6.8 7.3 1.9 2.2 2 0 0 2 2 2 0 Associated with HOX TRAP_alpha PF03896.16 OEU18309.1 - 2.8 7.1 6.2 3.3 6.8 4.6 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Menin PF05053.13 OEU18309.1 - 3 6.1 6.4 0.99 7.7 0.5 2.0 2 0 0 2 2 2 0 Menin GOLD_2 PF13897.6 OEU18309.1 - 3.6 8.1 9.6 5.4 7.5 4.5 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DHHC PF01529.20 OEU18310.1 - 4.4e-30 104.5 16.0 4.4e-30 104.5 16.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 OEU18310.1 - 6.4 7.5 10.5 0.98 10.1 5.6 2.2 2 0 0 2 2 2 0 Insulin-like growth factor binding protein HA PF03457.14 OEU18312.1 - 1.7e-19 69.9 0.3 1.4e-14 54.1 0.1 3.1 3 0 0 3 3 3 2 Helicase associated domain ADH_zinc_N PF00107.26 OEU18313.1 - 1.4e-08 34.8 0.0 5.1e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 OEU18313.1 - 0.00019 21.3 0.3 0.00037 20.3 0.3 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.12 OEU18313.1 - 0.00027 20.8 0.0 0.017 15.0 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 OEU18313.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU18313.1 - 0.038 13.4 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OEU18313.1 - 0.045 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF5122 PF17164.4 OEU18313.1 - 0.11 12.9 0.2 0.44 10.9 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller ACT_6 PF13740.6 OEU18314.1 - 3.6e-13 49.3 0.4 1.5e-08 34.5 0.1 2.1 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 OEU18314.1 - 6.6e-09 36.2 0.1 0.00025 21.6 0.0 2.1 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 OEU18314.1 - 1.7e-05 24.4 0.2 0.00021 21.0 0.0 2.3 2 1 0 2 2 2 1 ACT domain ACT_7 PF13840.6 OEU18314.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 ACT domain TMEM171 PF15471.6 OEU18315.1 - 0.036 13.1 0.5 0.053 12.5 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DDE_Tnp_4 PF13359.6 OEU18317.1 - 0.00089 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Chorion_2 PF03964.15 OEU18319.1 - 0.02 15.7 1.3 0.029 15.2 1.3 1.3 1 0 0 1 1 1 0 Chorion family 2 CRA PF06589.11 OEU18319.1 - 0.091 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Secretin_N_2 PF07655.13 OEU18319.1 - 0.5 10.9 10.1 0.74 10.4 10.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.11 OEU18319.1 - 1.5 7.0 4.9 1.6 6.9 4.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 OEU18319.1 - 4.5 5.2 12.4 4.5 5.2 12.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PGPGW PF09656.10 OEU18320.1 - 2.7e-08 33.2 0.0 3.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) zf-RING_12 PF17976.1 OEU18320.1 - 0.087 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Macscav_rec PF03523.13 OEU18320.1 - 0.64 10.0 3.1 8.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Macrophage scavenger receptor PfkB PF00294.24 OEU18321.1 - 1.7e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HGTP_anticodon PF03129.20 OEU18322.1 - 7e-23 80.6 0.1 1.4e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OEU18322.1 - 6.6e-12 45.8 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) LNS2 PF08235.13 OEU18322.1 - 0.13 11.7 0.0 11 5.5 0.0 2.1 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Ribosomal_S11 PF00411.19 OEU18323.1 - 2.5e-47 159.8 0.4 3.3e-47 159.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 OEU18323.1 - 0.099 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) CBM_25 PF03423.13 OEU18323.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Pkinase PF00069.25 OEU18326.1 - 3.9e-44 151.0 0.0 2.6e-43 148.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU18326.1 - 1e-15 57.7 0.0 3.4e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU18326.1 - 0.00049 20.1 0.0 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU18326.1 - 0.053 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADK_lid PF05191.14 OEU18326.1 - 0.094 12.7 0.2 0.094 12.7 0.2 1.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid ABC1 PF03109.16 OEU18326.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Macoilin PF09726.9 OEU18326.1 - 5.3 5.5 17.3 8 4.9 17.3 1.2 1 0 0 1 1 1 0 Macoilin family DASH_Spc34 PF08657.10 OEU18327.1 - 0.0077 16.1 0.9 0.015 15.1 0.9 1.4 1 0 0 1 1 1 1 DASH complex subunit Spc34 NDUF_B5 PF09781.9 OEU18327.1 - 3.3 7.3 6.8 14 5.2 1.0 2.2 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Peptidase_M16_M PF16187.5 OEU18328.1 - 1.8e-72 244.0 0.4 3.1e-72 243.2 0.4 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OEU18328.1 - 3e-38 131.1 0.0 9e-37 126.3 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OEU18328.1 - 4.4e-18 65.9 1.4 1.7e-13 51.0 0.2 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain NUDE_C PF04880.13 OEU18328.1 - 0.1 13.1 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF465 PF04325.13 OEU18331.1 - 0.09 12.8 2.6 0.28 11.2 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) ATP-synt_B PF00430.18 OEU18331.1 - 0.24 11.5 6.0 0.46 10.6 6.0 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PI3_PI4_kinase PF00454.27 OEU18333.1 - 4.7e-25 88.8 0.0 6e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OEU18333.1 - 0.058 12.7 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Trigger_C PF05698.14 OEU18333.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Dus PF01207.17 OEU18334.1 - 1.3e-63 215.0 0.0 4.6e-63 213.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FtsK_gamma PF09397.10 OEU18335.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Ftsk gamma domain TB2_DP1_HVA22 PF03134.19 OEU18336.1 - 1.4e-07 31.3 10.6 0.00047 20.0 2.6 3.1 2 0 0 2 2 2 2 TB2/DP1, HVA22 family DUF4611 PF15387.6 OEU18336.1 - 5.7 7.2 10.1 5.8 7.2 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DEAD PF00270.29 OEU18337.1 - 1.2e-38 132.6 0.1 4.5e-38 130.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU18337.1 - 2.5e-29 101.8 0.4 1.4e-26 93.0 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OEU18337.1 - 1.3e-06 28.6 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OEU18337.1 - 0.00093 18.6 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Peptidase_S80 PF07230.11 OEU18337.1 - 0.088 11.1 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) AAA_22 PF13401.6 OEU18337.1 - 0.099 12.9 0.6 0.67 10.2 0.6 2.3 1 1 0 1 1 1 0 AAA domain Adenine_glyco PF03352.13 OEU18339.1 - 2.5e-44 151.2 1.5 1.4e-25 90.1 0.3 2.3 2 0 0 2 2 2 2 Methyladenine glycosylase RXT2_N PF08595.11 OEU18339.1 - 4.7 7.2 12.4 1.1 9.2 5.6 2.3 2 1 0 2 2 2 0 RXT2-like, N-terminal Med3 PF11593.8 OEU18340.1 - 4.3 6.4 8.2 5.3 6.1 8.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal adh_short PF00106.25 OEU18341.1 - 1.4e-25 89.9 3.8 1.8e-22 79.8 1.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU18341.1 - 1.2e-16 61.0 1.0 2.5e-16 60.0 1.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU18341.1 - 7.5e-11 42.3 0.6 1.1e-10 41.7 0.6 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OEU18341.1 - 9.3e-05 22.5 0.1 0.00016 21.8 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OEU18341.1 - 0.0027 17.6 0.2 0.0046 16.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OEU18341.1 - 0.0089 15.2 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OEU18341.1 - 0.011 15.1 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU18341.1 - 0.043 13.3 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family potato_inhibit PF00280.18 OEU18342.1 - 1.1e-06 29.2 0.0 2.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Potato inhibitor I family Defensin_big PF14862.6 OEU18342.1 - 3.1 8.2 19.2 0.17 12.2 1.0 3.8 4 0 0 4 4 4 0 Big defensin adh_short PF00106.25 OEU18343.1 - 7.7e-31 107.1 0.0 9e-25 87.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU18343.1 - 1.7e-16 60.5 0.0 1.4e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU18343.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OEU18343.1 - 0.00042 20.3 0.2 0.00074 19.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OEU18343.1 - 0.016 14.7 0.9 0.28 10.6 0.9 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OEU18343.1 - 0.14 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Rhomboid PF01694.22 OEU18344.1 - 1.6e-27 96.4 10.2 1.8e-27 96.2 10.2 1.0 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OEU18344.1 - 3.6e-05 24.3 0.2 6.3e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) zf-MYND PF01753.18 OEU18345.1 - 1e-09 38.3 20.1 2.2e-09 37.3 20.1 1.6 1 0 0 1 1 1 1 MYND finger CcdA PF07362.12 OEU18345.1 - 2.3 8.7 8.2 0.1 13.1 2.4 1.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA zf-C6H2 PF15801.5 OEU18345.1 - 7.5 6.9 12.2 23 5.4 12.2 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding His_Phos_1 PF00300.22 OEU18346.1 - 3e-21 76.0 0.0 4.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1635 PF07795.11 OEU18346.1 - 4.8 7.0 9.6 31 4.3 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) ADK PF00406.22 OEU18347.1 - 2e-38 131.8 0.2 5.4e-38 130.5 0.2 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU18347.1 - 2.5e-27 96.0 0.0 3.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU18347.1 - 2.3e-10 41.1 0.0 5e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU18347.1 - 0.0045 17.1 0.3 0.016 15.4 0.3 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU18347.1 - 0.013 15.4 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OEU18347.1 - 0.078 13.4 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain TCR PF03638.15 OEU18348.1 - 9e-18 64.3 42.3 4.9e-12 45.9 22.0 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain zf-MYND PF01753.18 OEU18349.1 - 2.9e-06 27.3 15.2 5.1e-06 26.5 15.2 1.4 1 0 0 1 1 1 1 MYND finger Peptidase_M76 PF09768.9 OEU18351.1 - 1.1e-20 74.0 3.6 2.8e-14 53.3 1.7 2.4 2 0 0 2 2 2 2 Peptidase M76 family ANAPC_CDC26 PF10471.9 OEU18351.1 - 0.029 15.2 3.3 0.029 15.2 3.3 4.6 4 1 1 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 Presenilin PF01080.17 OEU18351.1 - 2.1 7.0 28.4 2.4 6.8 9.4 2.4 2 0 0 2 2 2 0 Presenilin HA2 PF04408.23 OEU18351.1 - 7.9 6.8 10.6 0.61 10.4 0.4 3.2 3 0 0 3 3 3 0 Helicase associated domain (HA2) Peptidase_S74 PF13884.6 OEU18352.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase zf-MYND PF01753.18 OEU18354.1 - 1.1e-05 25.4 15.5 2.5e-05 24.3 15.5 1.6 1 0 0 1 1 1 1 MYND finger XAP5 PF04921.14 OEU18355.1 - 1.1e-71 241.6 0.2 1.2e-71 241.4 0.2 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator AAA PF00004.29 OEU18356.1 - 1.6e-32 112.7 0.0 4.6e-15 56.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 OEU18356.1 - 2.6e-20 72.4 6.8 6.9e-09 35.8 1.6 3.9 3 0 0 3 3 3 3 AAA lid domain RuvB_N PF05496.12 OEU18356.1 - 1e-06 28.6 0.0 0.031 14.0 0.0 3.3 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OEU18356.1 - 3.6e-06 26.5 0.1 0.081 12.3 0.0 3.2 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU18356.1 - 5.5e-06 26.4 0.2 0.07 13.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU18356.1 - 1.1e-05 25.7 1.3 1.2 9.4 0.1 4.9 3 2 0 4 4 4 2 AAA domain AAA_30 PF13604.6 OEU18356.1 - 5.5e-05 23.0 0.2 0.0057 16.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OEU18356.1 - 5.9e-05 22.8 0.1 4.3 7.0 0.0 3.9 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_19 PF13245.6 OEU18356.1 - 0.00029 21.2 0.8 0.9 9.9 0.3 3.5 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.6 OEU18356.1 - 0.00072 20.0 1.2 1.3 9.4 0.0 3.4 4 1 0 4 4 3 1 AAA ATPase domain AAA_24 PF13479.6 OEU18356.1 - 0.0011 18.7 0.0 0.91 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU18356.1 - 0.0033 17.8 0.1 0.8 10.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 OEU18356.1 - 0.0043 16.8 0.0 2.6 7.7 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 OEU18356.1 - 0.014 15.5 0.0 1.9 8.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OEU18356.1 - 0.017 15.6 1.3 3.4 8.2 0.0 3.0 3 0 0 3 3 2 0 ABC transporter AAA_7 PF12775.7 OEU18356.1 - 0.018 14.5 0.1 6 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 OEU18356.1 - 0.022 14.8 0.0 4.3 7.4 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 OEU18356.1 - 0.029 14.9 6.7 2.6 8.6 0.3 3.9 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OEU18356.1 - 0.03 14.6 0.3 7.1 6.8 0.1 3.3 4 0 0 4 4 2 0 AAA domain Uso1_p115_head PF04869.14 OEU18356.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Torsin PF06309.11 OEU18356.1 - 0.083 13.0 0.0 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Torsin PhoH PF02562.16 OEU18356.1 - 0.096 12.1 0.0 14 5.0 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein OGG_N PF07934.12 OEU18356.1 - 0.15 12.2 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain RRN3 PF05327.11 OEU18356.1 - 3.8 5.9 7.0 6.4 5.2 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_12 PF13087.6 OEU18357.1 - 1.1e-40 139.4 0.0 3.2e-40 137.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OEU18357.1 - 4.2e-28 98.8 0.9 3.3e-25 89.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OEU18357.1 - 6.6e-16 59.0 0.0 3.9e-11 43.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 OEU18357.1 - 1.5e-11 44.8 0.0 5.4e-07 30.1 0.0 3.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OEU18357.1 - 5.2e-11 42.6 0.3 0.00084 19.1 0.0 4.1 3 1 1 4 4 4 3 AAA domain DUF2075 PF09848.9 OEU18357.1 - 2.6e-07 30.2 0.1 0.0013 18.1 0.0 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 OEU18357.1 - 2.3e-06 27.5 0.0 0.031 14.0 0.0 4.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 OEU18357.1 - 4.5e-06 26.7 0.8 0.057 13.4 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU18357.1 - 1.5e-05 25.3 0.4 0.14 12.5 0.0 4.1 3 1 1 4 4 3 1 AAA domain PhoH PF02562.16 OEU18357.1 - 2e-05 24.2 0.3 0.0013 18.2 0.1 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_7 PF12775.7 OEU18357.1 - 8.6e-05 22.1 0.1 0.55 9.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 OEU18357.1 - 0.00018 21.5 0.2 0.13 12.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 OEU18357.1 - 0.00022 21.7 0.6 0.48 10.8 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain Mg_chelatase PF01078.21 OEU18357.1 - 0.00022 20.7 0.0 0.38 10.1 0.0 3.0 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OEU18357.1 - 0.00028 20.3 0.1 0.33 10.3 0.0 2.5 2 0 0 2 2 2 2 KaiC ResIII PF04851.15 OEU18357.1 - 0.00042 20.4 0.4 0.014 15.4 0.0 3.3 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 OEU18357.1 - 0.00058 19.6 0.2 0.59 9.9 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 OEU18357.1 - 0.00068 19.4 0.1 0.32 10.7 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 OEU18357.1 - 0.00096 19.7 0.0 1.7 9.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OEU18357.1 - 0.001 19.2 0.0 0.046 13.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) UvrD-helicase PF00580.21 OEU18357.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 4.2 5 1 0 5 5 4 1 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 OEU18357.1 - 0.0012 19.0 0.1 0.61 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 OEU18357.1 - 0.004 16.3 0.7 0.08 12.0 0.0 2.8 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 OEU18357.1 - 0.0046 16.7 0.6 6.1 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain CENP-Q PF13094.6 OEU18357.1 - 0.0055 16.9 5.8 1.2 9.3 4.2 3.1 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit RNA_helicase PF00910.22 OEU18357.1 - 0.0085 16.5 0.0 4.7 7.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase DEAD PF00270.29 OEU18357.1 - 0.02 14.7 1.1 0.15 11.8 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 OEU18357.1 - 0.02 14.5 0.3 1.3 8.6 0.0 3.3 3 1 1 4 4 3 0 AAA domain IstB_IS21 PF01695.17 OEU18357.1 - 0.032 14.0 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 OEU18357.1 - 0.058 13.3 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Glutaredoxin2_C PF04399.13 OEU18358.1 - 0.0032 17.3 2.3 0.013 15.3 0.4 2.6 3 0 0 3 3 3 1 Glutaredoxin 2, C terminal domain GSH_synth_ATP PF03917.17 OEU18358.1 - 0.004 16.0 0.2 0.007 15.2 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain DUF2407_C PF13373.6 OEU18358.1 - 0.031 14.5 0.7 7.6 6.7 0.1 2.8 1 1 0 2 2 2 0 DUF2407 C-terminal domain Acetyltransf_1 PF00583.25 OEU18360.1 - 5.9e-13 49.1 0.0 1.1e-12 48.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU18360.1 - 2.2e-11 43.8 0.0 3.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU18360.1 - 2.2e-09 37.6 0.0 4.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU18360.1 - 1.3e-06 28.3 0.1 2.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OEU18360.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OEU18360.1 - 0.0034 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain POPLD PF08170.12 OEU18361.1 - 0.028 14.8 0.7 0.2 12.0 0.3 2.1 2 0 0 2 2 2 0 POPLD (NUC188) domain RWD PF05773.22 OEU18361.1 - 0.031 14.5 0.2 0.092 13.0 0.1 1.8 2 1 0 2 2 2 0 RWD domain Nup_retrotrp_bd PF10599.9 OEU18361.1 - 2.9 8.6 10.0 0.5 11.1 4.0 2.3 2 1 0 2 2 2 0 Retro-transposon transporting motif Methyltransf_21 PF05050.12 OEU18362.1 - 2.7e-07 30.8 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 OEU18362.1 - 0.058 12.7 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein NAD_binding_10 PF13460.6 OEU18364.1 - 1.7e-09 37.8 0.0 3.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Metallophos PF00149.28 OEU18365.1 - 1.9e-13 51.4 0.0 2.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2379 PF09543.10 OEU18365.1 - 0.0086 16.3 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2379) Peptidase_M6 PF05547.11 OEU18367.1 - 1.1e-10 40.5 4.9 2.1e-10 39.6 4.9 1.4 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 PT PF04886.12 OEU18367.1 - 6.7e-07 28.7 88.8 0.0026 17.3 14.3 5.8 1 1 3 4 4 4 3 PT repeat EF-hand_1 PF00036.32 OEU18367.1 - 0.073 12.7 0.1 0.27 10.9 0.1 1.9 1 0 0 1 1 1 0 EF hand PA26 PF04636.13 OEU18369.1 - 0.01 14.8 4.6 0.013 14.5 4.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FHIPEP PF00771.20 OEU18369.1 - 0.13 10.7 3.1 0.2 10.1 2.8 1.2 1 1 0 1 1 1 0 FHIPEP family DUF3675 PF12428.8 OEU18369.1 - 0.57 10.7 2.2 0.74 10.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) AIF_C PF14721.6 OEU18369.1 - 1.3 9.4 10.0 0.33 11.3 5.7 2.2 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CSG2 PF16965.5 OEU18369.1 - 1.9 7.3 5.7 2.7 6.9 5.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator CdiI_4 PF18624.1 OEU18370.1 - 0.079 13.4 1.6 2.7 8.5 0.2 2.8 2 0 0 2 2 2 0 CDI immunity protein DNA_methylase PF00145.17 OEU18371.1 - 9.8e-23 81.0 0.0 9.7e-16 58.0 0.0 2.0 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase PDZ_2 PF13180.6 OEU18372.1 - 0.00022 21.5 0.3 0.001 19.3 0.3 2.2 1 0 0 1 1 1 1 PDZ domain Wax2_C PF12076.8 OEU18372.1 - 0.094 12.4 0.0 11 5.7 0.0 3.3 3 0 0 3 3 3 0 WAX2 C-terminal domain PDZ PF00595.24 OEU18372.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.8 1 0 0 1 1 1 0 PDZ domain MatE PF01554.18 OEU18374.1 - 1.8e-31 109.0 22.8 5.1e-18 65.3 5.8 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU18374.1 - 4.5e-05 23.5 3.5 4.5e-05 23.5 3.5 3.9 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain NAD_binding_8 PF13450.6 OEU18375.1 - 1.3e-07 31.7 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU18375.1 - 0.027 14.5 0.1 0.52 10.3 0.1 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding ASFV_360 PF01671.16 OEU18376.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein CRAL_TRIO_N PF03765.15 OEU18377.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain SOR PF07682.11 OEU18377.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Sulphur oxygenase reductase SET PF00856.28 OEU18378.1 - 5e-12 46.5 0.4 5e-12 46.5 0.4 3.1 2 1 1 3 3 3 2 SET domain Mito_carr PF00153.27 OEU18378.1 - 0.18 11.7 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein Cwf_Cwc_15 PF04889.12 OEU18378.1 - 1.2 8.8 31.0 0.037 13.8 10.8 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Mitoc_mL59 PF18126.1 OEU18380.1 - 0.02 15.2 0.3 0.063 13.6 0.3 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 CUT PF02376.15 OEU18381.1 - 0.0012 19.0 0.4 1.9 8.7 0.2 2.3 2 0 0 2 2 2 2 CUT domain CRISPR_Cas9_WED PF18061.1 OEU18381.1 - 0.0015 18.6 0.8 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 CRISPR-Cas9 WED domain DUF4519 PF15012.6 OEU18381.1 - 0.24 11.6 1.4 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FRG2 PF15315.6 OEU18381.1 - 0.66 10.2 8.4 0.067 13.4 2.8 1.9 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 CRAL_TRIO PF00650.20 OEU18382.1 - 4.7e-17 62.2 0.1 1.2e-16 60.8 0.1 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OEU18382.1 - 5.3e-06 26.5 0.6 1.4e-05 25.2 0.6 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Lipid_bd PF12888.7 OEU18382.1 - 0.0068 16.8 0.9 0.016 15.6 0.9 1.6 1 0 0 1 1 1 1 Lipid-binding putative hydrolase DARPP-32 PF05395.12 OEU18383.1 - 0.024 14.9 0.2 0.029 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 WW PF00397.26 OEU18385.1 - 4e-09 36.4 1.4 1.3e-08 34.8 1.4 2.0 1 0 0 1 1 1 1 WW domain PhyH PF05721.13 OEU18385.1 - 7.9e-09 36.1 0.7 5e-08 33.4 0.3 2.7 1 1 1 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Cys_box PF17869.1 OEU18385.1 - 0.0022 18.1 1.4 0.0022 18.1 1.4 2.0 2 0 0 2 2 2 1 Anosmin cysteine rich domain PT PF04886.12 OEU18386.1 - 0.0034 16.9 8.9 0.0034 16.9 8.9 6.3 4 2 0 4 4 4 1 PT repeat Sec20 PF03908.13 OEU18386.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Sec20 Fusion_gly PF00523.18 OEU18386.1 - 0.32 9.2 4.3 0.46 8.7 4.3 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DASH_Dad1 PF08649.10 OEU18386.1 - 8 6.7 10.5 16 5.8 10.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 E1-E2_ATPase PF00122.20 OEU18387.1 - 4.5e-46 156.6 0.3 1e-45 155.5 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OEU18387.1 - 8.3e-27 94.8 0.0 1.2e-26 94.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OEU18387.1 - 0.034 13.9 1.8 0.097 12.4 0.8 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OEU18388.1 - 1.5e-51 175.3 0.0 2.2e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU18388.1 - 9.5e-24 84.1 0.0 1.9e-23 83.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU18388.1 - 1.3e-06 27.9 0.0 7.3e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OEU18388.1 - 1.5e-05 24.0 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OEU18388.1 - 4.8e-05 22.5 0.3 6.4e-05 22.0 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OEU18388.1 - 0.00041 20.1 1.0 0.024 14.3 0.1 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DUF3860 PF12976.7 OEU18388.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Porphyrn_cat_1 PF18206.1 OEU18389.1 - 0.009 16.6 2.4 0.013 16.1 0.5 2.1 2 0 0 2 2 2 1 Porphyranase catalytic subdomain 1 OppC_N PF12911.7 OEU18389.1 - 0.058 13.4 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ly49 PF08391.10 OEU18389.1 - 2.6 8.4 7.0 2.3 8.6 0.2 2.7 2 2 0 2 2 2 0 Ly49-like protein, N-terminal region Proteasome PF00227.26 OEU18390.1 - 8.3e-41 139.6 0.1 9.4e-41 139.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit S-AdoMet_synt_C PF02773.16 OEU18391.1 - 9.5e-68 226.5 0.0 1.9e-67 225.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OEU18391.1 - 1.1e-46 158.0 0.0 2e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OEU18391.1 - 6e-43 145.6 1.4 2.1e-42 143.8 0.2 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain F420_oxidored PF03807.17 OEU18392.1 - 2.9e-10 40.6 0.1 4.1e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OEU18392.1 - 5.5e-07 29.9 0.1 7.8e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OEU18392.1 - 8.6e-05 22.5 0.4 0.00013 21.9 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OEU18392.1 - 0.00012 22.1 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OEU18392.1 - 0.00066 19.2 0.1 0.00091 18.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OEU18392.1 - 0.00072 19.1 0.0 0.00086 18.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OEU18392.1 - 0.0047 16.5 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OEU18392.1 - 0.0064 15.9 0.0 0.0083 15.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OEU18392.1 - 0.013 16.0 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OEU18392.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 OEU18392.1 - 0.027 14.6 0.1 0.16 12.1 0.2 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 OEU18392.1 - 0.13 11.9 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.32 OEU18393.1 - 5e-25 87.3 9.2 7.8e-06 26.5 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU18393.1 - 6.7e-18 64.8 4.6 0.00021 21.5 0.8 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU18393.1 - 2e-06 27.8 0.0 0.0003 20.7 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OEU18393.1 - 0.0068 15.4 0.1 0.7 8.8 0.0 3.1 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 OEU18393.1 - 0.017 13.1 0.3 2.8 5.8 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Ysc84 PF04366.12 OEU18394.1 - 7.8e-41 138.8 0.0 1.5e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 OEU18394.1 - 3.7e-20 71.8 7.5 6.1e-20 71.1 7.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger TraT PF05818.12 OEU18394.1 - 0.00097 18.9 0.6 0.0027 17.4 0.6 1.7 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein FYVE_2 PF02318.16 OEU18394.1 - 0.017 15.4 3.8 0.029 14.6 3.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_2 PF13639.6 OEU18394.1 - 0.1 12.9 10.1 0.19 12.1 6.1 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OEU18394.1 - 2.1 8.3 10.7 3.9 7.5 10.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 OEU18394.1 - 9.3 6.4 10.4 17 5.6 0.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon Sugar_tr PF00083.24 OEU18395.1 - 2e-87 294.0 17.2 2.3e-87 293.7 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU18395.1 - 4.5e-19 68.6 26.0 6.5e-19 68.1 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2870 PF11069.8 OEU18396.1 - 0.51 10.7 6.3 0.11 12.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Complex1_LYR PF05347.15 OEU18397.1 - 7.3e-07 29.1 0.5 1.7e-06 27.9 0.0 1.9 2 1 0 2 2 2 1 Complex 1 protein (LYR family) DEAD PF00270.29 OEU18398.1 - 7.1e-46 156.2 0.0 1.3e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU18398.1 - 5.4e-30 104.0 0.0 3.3e-29 101.5 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OEU18398.1 - 0.00013 20.9 0.0 0.59 8.8 0.0 2.9 3 0 0 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OEU18398.1 - 0.00022 20.5 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OEU18398.1 - 0.00038 20.5 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CRAL_TRIO PF00650.20 OEU18399.1 - 1.2e-12 47.9 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain SOUL PF04832.12 OEU18400.1 - 2.5e-35 122.1 0.0 3.6e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein zf-MYND PF01753.18 OEU18401.1 - 3.5e-06 27.0 14.9 6.8e-06 26.1 14.9 1.5 1 0 0 1 1 1 1 MYND finger Met_10 PF02475.16 OEU18402.1 - 1.7e-27 96.5 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 OEU18402.1 - 6e-06 25.9 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OEU18402.1 - 3.1e-05 23.9 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OEU18402.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 OEU18402.1 - 0.00047 19.6 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OEU18402.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PRMT5 PF05185.16 OEU18402.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.6 OEU18402.1 - 0.026 15.2 0.0 0.046 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OEU18402.1 - 0.028 13.4 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase BppU_N PF10651.9 OEU18402.1 - 0.083 12.6 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 BppU N-terminal domain RRM_1 PF00076.22 OEU18403.1 - 1.9e-05 24.4 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPS31 PF17067.5 OEU18403.1 - 0.0041 17.3 0.4 0.009 16.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S31e DivIC PF04977.15 OEU18403.1 - 0.041 13.6 0.6 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_L4 PF00573.22 OEU18404.1 - 1.1e-43 149.2 0.2 1.4e-43 148.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rep_N PF08724.10 OEU18405.1 - 0.21 11.3 3.4 1.4 8.6 0.2 2.2 1 1 1 2 2 2 0 Rep protein catalytic domain like Adaptin_N PF01602.20 OEU18406.1 - 8.6e-145 483.2 9.1 1.1e-144 482.9 9.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OEU18406.1 - 1.4e-64 217.0 0.6 5.8e-63 211.8 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 OEU18406.1 - 1.5e-26 92.7 0.0 6.2e-26 90.7 0.0 2.2 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 OEU18406.1 - 3e-16 59.6 8.8 5.7e-08 33.0 0.6 5.7 2 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 OEU18406.1 - 4.7e-08 32.6 5.1 0.17 12.2 0.1 5.9 5 0 0 5 5 5 2 HEAT repeat Cnd3 PF12719.7 OEU18406.1 - 0.00017 20.9 0.5 0.095 11.9 0.1 2.9 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OEU18406.1 - 0.00022 21.1 1.6 0.29 11.3 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.20 OEU18406.1 - 0.00033 20.9 2.0 0.00068 19.9 2.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain UNC45-central PF11701.8 OEU18406.1 - 0.00066 19.7 0.5 0.14 12.1 0.0 3.2 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 OEU18406.1 - 0.0019 18.3 2.2 5.2 7.3 0.1 4.6 2 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 OEU18406.1 - 0.0044 16.8 1.4 0.043 13.6 0.0 2.9 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 OEU18406.1 - 0.0082 16.6 7.8 2.2 8.9 0.1 4.9 5 1 1 6 6 5 1 HEAT-like repeat Sec7_N PF12783.7 OEU18406.1 - 0.022 14.6 1.6 0.14 12.0 0.3 2.6 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal API5 PF05918.11 OEU18406.1 - 0.054 12.3 1.3 1.1 8.0 0.0 2.8 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) CLASP_N PF12348.8 OEU18406.1 - 0.066 12.8 0.6 7.2 6.1 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal Arm_2 PF04826.13 OEU18406.1 - 0.073 12.5 0.0 0.073 12.5 0.0 3.0 4 0 0 4 4 4 0 Armadillo-like PT PF04886.12 OEU18407.1 - 2.7 7.6 18.4 39 3.9 18.4 2.5 1 1 0 1 1 1 0 PT repeat Amidase_6 PF12671.7 OEU18408.1 - 0.01 15.9 0.0 3.7 7.6 0.0 2.2 1 1 1 2 2 2 0 Putative amidase domain Herpes_UL49_2 PF04823.12 OEU18408.1 - 0.014 15.5 0.5 0.024 14.8 0.4 1.4 1 1 0 1 1 1 0 Herpesvirus UL49 tegument protein Cons_hypoth698 PF03601.14 OEU18409.1 - 0.14 11.0 1.1 0.22 10.4 1.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 DnaJ-X PF14308.6 OEU18410.1 - 7.9e-36 123.5 1.6 7.9e-36 123.5 1.6 3.6 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 OEU18410.1 - 1.5e-23 82.6 1.1 9.5e-23 80.1 1.1 2.5 1 0 0 1 1 1 1 DnaJ domain FUSC_2 PF13515.6 OEU18411.1 - 0.026 14.7 0.3 0.036 14.2 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Ac76 PF05814.11 OEU18411.1 - 0.48 10.5 5.4 2.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Orf76 (Ac76) Sec7 PF01369.20 OEU18412.1 - 1.3e-59 201.0 0.0 3.5e-59 199.6 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OEU18412.1 - 2.2e-22 79.7 3.5 2.2e-22 79.7 3.5 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal A1_Propeptide PF07966.12 OEU18412.1 - 1 9.3 5.3 0.74 9.7 0.5 2.9 3 0 0 3 3 3 0 A1 Propeptide Sulfate_transp PF00916.20 OEU18413.1 - 2e-24 86.0 22.5 2.6e-24 85.7 22.5 1.1 1 0 0 1 1 1 1 Sulfate permease family Peroxidase_2 PF01328.17 OEU18414.1 - 5.1e-28 98.9 0.0 7.9e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Sec63 PF02889.16 OEU18415.1 - 1.6e-26 93.0 0.3 2.3e-26 92.5 0.3 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 OEU18415.1 - 1.5e-18 66.7 0.6 7.8e-18 64.4 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain TssO PF17561.2 OEU18415.1 - 0.58 10.2 5.0 13 5.9 0.0 2.9 3 1 0 3 3 3 0 Type VI secretion system, TssO Mpv17_PMP22 PF04117.12 OEU18416.1 - 3e-15 56.2 0.4 6.6e-15 55.1 0.4 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family RXT2_N PF08595.11 OEU18417.1 - 0.39 10.7 10.3 1.5 8.9 0.6 3.2 3 0 0 3 3 3 0 RXT2-like, N-terminal PIEZO PF15917.5 OEU18417.1 - 6.7 6.1 11.4 0.21 11.1 2.3 2.7 3 1 0 3 3 3 0 Piezo S4 PF01479.25 OEU18418.1 - 6.3e-09 35.4 0.2 1.1e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 S4 domain MnmE_helical PF12631.7 OEU18419.1 - 1.3e-44 152.8 3.8 2.1e-44 152.2 3.8 1.3 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 OEU18419.1 - 8.3e-35 119.6 0.0 1.9e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 OEU18419.1 - 2.9e-21 75.7 0.2 6.1e-21 74.6 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU18419.1 - 4.4e-09 36.0 0.0 7.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU18419.1 - 1.1e-05 25.6 0.1 0.0005 20.2 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 OEU18419.1 - 0.00021 21.8 0.1 0.00055 20.5 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 OEU18419.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU18419.1 - 0.059 13.9 0.2 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OEU18419.1 - 0.07 13.0 0.3 0.67 9.8 0.0 2.5 2 2 0 2 2 2 0 RsgA GTPase RuvB_N PF05496.12 OEU18419.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRPRB PF09439.10 OEU18419.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 OEU18419.1 - 0.095 12.2 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 OEU18419.1 - 0.15 11.6 0.1 0.75 9.4 0.1 2.1 1 1 0 1 1 1 0 Ras family tRNA-synt_1d PF00750.19 OEU18420.1 - 5.9e-115 383.9 0.0 7.2e-115 383.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OEU18420.1 - 6.6e-18 65.0 0.2 1.8e-17 63.6 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OEU18420.1 - 0.0039 17.7 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 OEU18420.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Mistic PF11458.8 OEU18420.1 - 0.29 11.1 1.1 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Membrane-integrating protein Mistic GrpE PF01025.19 OEU18423.1 - 1.2e-14 54.4 16.9 3.2e-13 49.7 17.0 2.7 1 1 0 1 1 1 1 GrpE Trypan_PARP PF05887.11 OEU18423.1 - 0.00028 20.9 2.7 0.00028 20.9 2.7 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Atg14 PF10186.9 OEU18423.1 - 0.0022 17.1 10.2 0.003 16.7 10.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_S8 PF00082.22 OEU18423.1 - 0.028 13.7 2.6 0.071 12.4 0.1 2.4 3 0 0 3 3 3 0 Subtilase family Phage_tail_T PF06223.12 OEU18423.1 - 0.038 14.5 0.7 0.43 11.1 0.0 2.5 2 0 0 2 2 2 0 Minor tail protein T AMP-binding PF00501.28 OEU18423.1 - 0.038 12.6 0.5 0.055 12.1 0.5 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Myc_N PF01056.18 OEU18423.1 - 0.04 13.8 13.9 13 5.5 0.0 2.1 1 1 1 2 2 2 0 Myc amino-terminal region D123 PF07065.14 OEU18423.1 - 0.058 12.5 7.5 0.13 11.4 7.5 1.5 1 0 0 1 1 1 0 D123 O-antigen_lig PF13425.6 OEU18423.1 - 0.069 11.9 1.7 0.11 11.3 1.7 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CD20 PF04103.15 OEU18423.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 CD20-like family Tim54 PF11711.8 OEU18423.1 - 0.097 11.4 7.4 0.17 10.6 7.4 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 OEU18423.1 - 0.12 10.9 8.7 0.21 10.1 8.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peroxin-13_N PF04088.13 OEU18423.1 - 0.23 11.8 2.3 0.3 11.4 0.5 2.0 1 1 1 2 2 2 0 Peroxin 13, N-terminal region Sigma70_ner PF04546.13 OEU18423.1 - 0.43 10.4 18.0 0.023 14.6 10.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Med13_C PF06333.12 OEU18423.1 - 0.46 9.7 11.5 3.9 6.6 11.5 2.0 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Serinc PF03348.15 OEU18423.1 - 0.62 8.9 2.1 0.99 8.3 2.1 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) PA26 PF04636.13 OEU18423.1 - 0.62 8.9 8.3 0.82 8.5 8.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SID-1_RNA_chan PF13965.6 OEU18423.1 - 0.85 8.0 2.8 0.96 7.8 2.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LCIB_C_CA PF18599.1 OEU18423.1 - 0.87 8.8 4.1 2.8 7.2 4.0 1.8 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SLC12 PF03522.15 OEU18423.1 - 0.95 8.4 8.9 1.5 7.7 8.9 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 OEU18423.1 - 1.2 7.9 9.8 1.7 7.3 9.8 1.4 1 0 0 1 1 1 0 Presenilin DUF3801 PF12687.7 OEU18423.1 - 1.3 9.1 14.6 2.3 8.3 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Med30 PF11315.8 OEU18423.1 - 1.3 9.2 10.2 1 9.5 1.2 2.4 1 1 1 2 2 2 0 Mediator complex subunit 30 PPL5 PF18168.1 OEU18423.1 - 2 7.6 7.6 3.4 6.9 7.6 1.5 1 0 0 1 1 1 0 Prim-pol family 5 TFB6 PF17110.5 OEU18423.1 - 2.3 8.0 9.3 0.7 9.6 5.1 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF2052 PF09747.9 OEU18423.1 - 2.5 8.2 21.9 0.27 11.3 17.0 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 OEU18423.1 - 2.7 6.1 24.6 0.058 11.6 18.1 1.5 2 0 0 2 2 2 0 Nop14-like family Membralin PF09746.9 OEU18423.1 - 3.9 6.4 6.0 5 6.1 6.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein Vfa1 PF08432.10 OEU18423.1 - 4.1 7.7 20.5 0.58 10.5 15.2 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DREPP PF05558.12 OEU18423.1 - 6.2 6.7 21.1 1.3 8.9 16.9 2.0 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide DUF4407 PF14362.6 OEU18423.1 - 6.6 6.0 10.3 9.6 5.5 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 OEU18423.1 - 7.4 4.6 15.7 11 4.0 15.7 1.2 1 0 0 1 1 1 0 Hsp70 protein Ly49 PF08391.10 OEU18424.1 - 7.2 7.0 6.7 1.4 9.3 0.6 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region EST1_DNA_bind PF10373.9 OEU18425.1 - 9.7e-20 71.2 11.2 9.7e-20 71.2 11.2 2.4 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OEU18425.1 - 1e-12 48.9 10.9 2.2e-11 44.6 1.0 3.4 3 0 0 3 3 3 2 Telomerase activating protein Est1 RasGEF_N PF00618.20 OEU18425.1 - 0.44 10.8 13.8 0.074 13.3 3.5 3.8 4 0 0 4 4 4 0 RasGEF N-terminal motif tRNA-synt_1e PF01406.19 OEU18426.1 - 8.4e-105 350.4 0.2 8.4e-105 350.4 0.2 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OEU18426.1 - 4e-10 39.0 0.1 0.00031 19.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 OEU18426.1 - 0.00028 19.9 0.0 0.036 13.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 OEU18426.1 - 0.012 16.0 2.2 0.012 16.0 2.2 2.3 2 1 0 2 2 2 0 DALR domain Sir1 PF11603.8 OEU18426.1 - 0.093 13.2 2.4 0.25 11.8 2.4 1.7 1 0 0 1 1 1 0 Regulatory protein Sir1 RNA_pol_Rpb1_5 PF04998.17 OEU18427.1 - 2.1e-86 289.7 0.1 3.3e-86 289.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OEU18427.1 - 1.9e-56 190.9 0.0 3.7e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 OEU18427.1 - 6.6e-37 127.5 0.1 1.3e-36 126.5 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 OEU18427.1 - 4.2e-32 111.2 0.0 1.7e-31 109.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OEU18427.1 - 6.4e-18 64.7 0.0 2.7e-17 62.7 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PCB_OB PF17092.5 OEU18427.1 - 0.036 14.8 0.0 2.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain BUD22 PF09073.10 OEU18427.1 - 3.5 6.8 11.0 6.5 6.0 11.0 1.3 1 0 0 1 1 1 0 BUD22 Glyco_hydro_47 PF01532.20 OEU18428.1 - 7.4e-151 503.1 0.0 8.4e-151 502.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 OEU18428.1 - 0.019 14.1 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 MHC2-interact PF09307.10 OEU18431.1 - 0.063 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 CLIP, MHC2 interacting HemX PF04375.14 OEU18431.1 - 0.071 12.4 0.3 0.1 11.8 0.3 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase YbaB_DNA_bd PF02575.16 OEU18431.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family ABC_export PF16962.5 OEU18431.1 - 1.7 7.0 4.2 30 2.9 0.1 3.1 2 1 1 3 3 3 0 Putative ABC exporter Sulfotransfer_3 PF13469.6 OEU18432.1 - 0.0019 18.6 0.3 0.0068 16.8 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase family RXT2_N PF08595.11 OEU18433.1 - 0.046 13.8 18.0 0.38 10.8 7.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIE-A_C PF11521.8 OEU18433.1 - 0.081 13.2 0.8 0.081 13.2 0.8 4.1 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha DUF5506 PF17611.2 OEU18433.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5506) OAD_gamma PF04277.13 OEU18433.1 - 1.6 9.4 6.3 0.56 10.8 0.8 2.7 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.11 OEU18433.1 - 9.1 6.5 35.0 2.7 8.2 16.0 2.6 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 DUF1350 PF07082.11 OEU18434.1 - 2.1e-24 86.2 0.0 8.1e-24 84.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1350) DUF908 PF06012.12 OEU18434.1 - 1.4 8.3 10.4 3.1 7.1 10.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 OEU18434.1 - 8.7 5.0 13.0 16 4.1 13.0 1.4 1 0 0 1 1 1 0 Presenilin FGE-sulfatase PF03781.16 OEU18435.1 - 3.8e-49 167.6 6.8 1.4e-48 165.7 6.8 1.8 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DNA_pol_phi PF04931.13 OEU18435.1 - 0.96 7.5 8.1 1.3 7.0 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M24 PF00557.24 OEU18436.1 - 6.4e-48 163.2 0.0 7.8e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Nexin_C PF08628.12 OEU18437.1 - 7.3e-16 58.7 0.1 2e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 OEU18437.1 - 0.0017 18.3 0.0 0.0078 16.2 0.0 2.1 2 1 0 2 2 2 1 PX domain NES_C_h PF18208.1 OEU18437.1 - 0.05 13.9 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain Ribosomal_S8 PF00410.19 OEU18437.1 - 0.11 12.5 0.5 0.28 11.2 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S8 MIP-T3 PF10243.9 OEU18439.1 - 0.067 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain Orn_DAP_Arg_deC PF00278.22 OEU18440.1 - 2.2e-16 59.9 0.0 3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Spermine_synth PF01564.17 OEU18441.1 - 2.4e-32 111.9 0.0 4.1e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OEU18441.1 - 0.00094 19.0 0.2 0.0016 18.3 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_30 PF05430.11 OEU18441.1 - 0.0043 16.9 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase UPF0146 PF03686.13 OEU18441.1 - 0.005 16.7 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) Methyltransf_25 PF13649.6 OEU18441.1 - 0.052 14.3 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NEMO PF11577.8 OEU18442.1 - 0.0081 16.2 5.1 0.0081 16.2 5.1 4.3 4 0 0 4 4 4 1 NF-kappa-B essential modulator NEMO Filament PF00038.21 OEU18442.1 - 0.33 10.5 37.0 0.44 10.1 19.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 OEU18442.1 - 0.43 10.9 9.3 4 7.8 2.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 OEU18442.1 - 0.52 9.5 27.9 1.2 8.3 9.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein T7SS_ESX_EspC PF10824.8 OEU18442.1 - 0.87 10.1 7.2 1.4 9.4 0.3 3.1 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm ATG16 PF08614.11 OEU18442.1 - 3.1 8.0 37.7 0.92 9.7 19.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 OEU18442.1 - 3.5 7.3 43.6 8 6.1 17.2 2.9 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 OEU18442.1 - 5.5 7.0 13.1 4.8 7.2 0.2 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 OEU18442.1 - 5.6 7.2 46.0 1.1 9.5 1.0 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF4662 PF15578.6 OEU18442.1 - 8.4 6.1 13.3 0.2 11.4 6.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4662) Myosin_head PF00063.21 OEU18443.1 - 6.2e-177 589.8 0.0 9e-177 589.3 0.0 1.2 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 OEU18443.1 - 0.016 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OEU18443.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OEU18443.1 - 0.16 12.2 0.0 0.62 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 OEU18443.1 - 0.16 11.4 0.1 14 5.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain KASH_CCD PF14662.6 OEU18444.1 - 0.0086 15.9 1.1 0.0086 15.9 1.1 3.5 1 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.6 OEU18444.1 - 0.012 15.7 30.2 0.026 14.6 15.2 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CCDC53 PF10152.9 OEU18444.1 - 0.19 12.2 9.7 0.1 13.0 7.7 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Myosin_head PF00063.21 OEU18445.1 - 5e-176 586.8 0.1 6.2e-176 586.5 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 OEU18445.1 - 0.019 15.4 0.1 0.064 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain POX PF07526.11 OEU18445.1 - 0.03 14.9 0.1 0.1 13.2 0.0 1.9 2 0 0 2 2 2 0 Associated with HOX AAA_22 PF13401.6 OEU18445.1 - 0.16 12.3 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 OEU18445.1 - 0.26 11.2 0.7 0.8 9.7 0.7 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank_4 PF13637.6 OEU18446.1 - 1.1e-28 99.2 0.4 8.2e-11 42.2 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU18446.1 - 5.2e-22 77.3 0.4 9.2e-05 22.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 OEU18446.1 - 5.7e-21 74.9 0.3 1.7e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU18446.1 - 1.7e-18 66.4 0.7 5e-06 26.7 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU18446.1 - 1.9e-18 64.6 0.2 6.8e-05 23.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat DUF3013 PF11217.8 OEU18446.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) DHHC PF01529.20 OEU18447.1 - 4.3e-25 88.4 13.1 4.3e-25 88.4 13.1 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Helicase_Sgs1 PF11408.8 OEU18447.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase DUF555 PF04475.12 OEU18448.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF555) PAS_9 PF13426.7 OEU18451.1 - 5.2e-19 68.4 0.3 1.6e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.15 OEU18451.1 - 2e-07 31.0 11.3 2e-07 31.0 11.3 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OEU18451.1 - 7.2e-07 29.2 11.4 7.2e-07 29.2 11.4 1.6 1 1 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 OEU18451.1 - 8.7e-07 29.1 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OEU18451.1 - 4e-06 26.8 0.0 2.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OEU18451.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OEU18451.1 - 0.035 14.1 0.0 0.24 11.5 0.0 2.3 2 1 1 3 3 3 0 PAS domain MSC PF09402.10 OEU18452.1 - 9e-05 22.1 2.8 0.0001 21.9 2.8 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Bac_transf PF02397.16 OEU18452.1 - 0.0067 16.1 0.1 0.0083 15.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial sugar transferase Ribosomal_L13e PF01294.18 OEU18453.1 - 3.2e-55 186.8 1.6 4.6e-55 186.3 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e YlmH_RBD PF17774.1 OEU18454.1 - 0.14 12.5 0.1 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Putative RNA-binding domain in YlmH Bac_export_3 PF01313.19 OEU18454.1 - 0.28 11.1 2.6 0.72 9.8 1.6 2.3 2 0 0 2 2 2 0 Bacterial export proteins, family 3 LapA_dom PF06305.11 OEU18454.1 - 3 7.7 6.8 7.7 6.4 0.9 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Tir_receptor_C PF07489.11 OEU18455.1 - 0.015 15.3 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus AMP-binding PF00501.28 OEU18456.1 - 6.9e-90 301.7 0.1 9.1e-90 301.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OEU18456.1 - 5.6e-24 84.9 0.1 1.2e-23 83.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OEU18456.1 - 6.9e-19 67.5 0.1 1.7e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 OEU18456.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Hydrolase_6 PF13344.6 OEU18458.1 - 8.8e-29 99.6 0.0 1.9e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU18458.1 - 2.5e-19 69.1 0.0 7.2e-19 67.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OEU18458.1 - 1.6e-08 35.1 0.2 1.6e-06 28.6 0.2 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OEU18458.1 - 1.7e-07 31.5 0.1 0.02 15.0 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OEU18458.1 - 0.0022 17.6 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase 5_nucleotid PF05761.14 OEU18458.1 - 0.15 10.9 0.1 0.65 8.8 0.0 1.8 2 0 0 2 2 2 0 5' nucleotidase family PK PF00224.21 OEU18459.1 - 6e-148 492.4 1.0 1.6e-147 490.9 0.3 1.8 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OEU18459.1 - 2.1e-24 86.0 4.7 5.4e-24 84.7 4.7 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OEU18459.1 - 0.0062 15.7 1.4 0.035 13.2 0.6 2.5 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family RNase_P_Rpp14 PF01900.19 OEU18459.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Rpp14/Pop5 family DUF2577 PF10844.8 OEU18459.1 - 0.12 12.6 0.1 1.3 9.3 0.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2577) Frigida PF07899.11 OEU18460.1 - 1.5 8.0 6.5 1.3 8.2 1.0 2.2 2 0 0 2 2 2 0 Frigida-like protein IL1_propep PF02394.16 OEU18460.1 - 1.7 9.6 7.8 0.36 11.8 3.2 2.3 2 0 0 2 2 2 0 Interleukin-1 propeptide Metallophos PF00149.28 OEU18461.1 - 7.7e-07 29.8 2.4 0.0001 22.9 2.4 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.32 OEU18462.1 - 0.08 13.8 4.3 16 6.6 0.3 3.9 3 1 0 3 3 3 0 WD domain, G-beta repeat EF-hand_7 PF13499.6 OEU18463.1 - 1.2e-05 25.6 4.1 0.07 13.6 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU18463.1 - 2.5e-05 23.6 1.5 0.0043 16.5 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OEU18463.1 - 4.2e-05 22.8 6.1 0.00082 18.8 0.3 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OEU18463.1 - 0.00063 19.5 2.7 0.047 13.6 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU18463.1 - 0.032 14.1 1.9 0.91 9.4 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain pair Ribosomal_60s PF00428.19 OEU18464.1 - 0.0056 17.2 10.4 0.026 15.1 10.4 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Cofilin_ADF PF00241.20 OEU18465.1 - 7.1e-37 125.9 0.1 8.3e-37 125.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SSV1_ORF_D-335 PF07935.11 OEU18465.1 - 0.016 15.4 0.1 0.03 14.6 0.1 1.5 1 0 0 1 1 1 0 ORF D-335-like protein ATP-synt_ab PF00006.25 OEU18465.1 - 0.094 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ORMDL PF04061.14 OEU18466.1 - 5.3e-29 100.8 2.7 5.9e-29 100.6 2.7 1.0 1 0 0 1 1 1 1 ORMDL family BT1 PF03092.16 OEU18467.1 - 0.26 9.5 0.0 0.34 9.1 0.0 1.1 1 0 0 1 1 1 0 BT1 family FTZ PF03867.14 OEU18467.1 - 0.86 9.1 8.9 0.13 11.8 2.8 1.9 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region TylF PF05711.11 OEU18468.1 - 3e-12 46.4 0.0 3e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 OEU18468.1 - 2.5e-10 41.3 0.0 4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU18468.1 - 0.13 12.0 0.3 3 7.7 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Ank_5 PF13857.6 OEU18470.1 - 8.6e-05 22.7 0.0 0.0029 17.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU18470.1 - 0.00062 20.3 0.0 0.0032 18.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU18470.1 - 0.037 14.6 0.1 1.5 9.5 0.1 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) tRNA_bind PF01588.20 OEU18471.1 - 2e-28 98.3 0.0 2.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain F_bP_aldolase PF01116.20 OEU18472.1 - 5.7e-80 268.8 0.0 6.7e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AP_endonuc_2 PF01261.24 OEU18472.1 - 0.035 13.5 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF2325 PF10087.9 OEU18472.1 - 0.14 12.3 0.0 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Enolase_C PF00113.22 OEU18473.1 - 3.2e-131 436.9 0.0 4.1e-131 436.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OEU18473.1 - 1.7e-53 180.2 0.1 3.1e-53 179.4 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OEU18473.1 - 1.7e-08 34.3 0.0 3.6e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OEU18473.1 - 1.4e-05 24.4 1.5 2.4e-05 23.6 0.3 1.9 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus CBFD_NFYB_HMF PF00808.23 OEU18474.1 - 1.3e-20 73.4 0.1 2.5e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU18474.1 - 3.5e-14 53.3 1.5 4e-14 53.1 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF3543 PF12063.8 OEU18474.1 - 0.014 14.8 3.6 0.94 8.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3543) Recombinase PF07508.13 OEU18475.1 - 0.13 12.7 1.8 0.64 10.5 0.4 2.7 2 1 0 2 2 2 0 Recombinase Med21 PF11221.8 OEU18476.1 - 0.088 13.1 0.9 2 8.7 0.1 2.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF948 PF06103.11 OEU18476.1 - 1.4 9.2 7.1 13 6.1 0.4 4.2 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) NAD_binding_10 PF13460.6 OEU18477.1 - 2.4e-24 86.3 0.0 8e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU18477.1 - 1.1e-07 31.7 0.2 2.8e-07 30.3 0.1 1.7 2 1 1 3 3 3 1 NmrA-like family Epimerase PF01370.21 OEU18477.1 - 6.2e-07 29.1 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OEU18477.1 - 0.00052 20.1 0.6 0.0014 18.8 0.6 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OEU18477.1 - 0.00083 18.6 0.0 0.0017 17.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 OEU18477.1 - 0.0013 18.2 0.3 0.0023 17.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 OEU18477.1 - 0.0018 17.4 0.4 0.0031 16.6 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OEU18477.1 - 0.0026 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OEU18477.1 - 0.0099 15.0 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OEU18477.1 - 0.046 13.8 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 OEU18477.1 - 0.078 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 OEU18481.1 - 6.9e-21 74.6 0.0 1.2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU18481.1 - 8.4e-14 51.7 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DnaJ PF00226.31 OEU18482.1 - 5.6e-21 74.4 1.3 6.6e-21 74.2 1.3 1.1 1 0 0 1 1 1 1 DnaJ domain DUF2973 PF11189.8 OEU18482.1 - 0.072 13.2 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Bromodomain PF00439.25 OEU18483.1 - 3.3e-11 43.1 0.2 3.7e-11 42.9 0.2 1.0 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 OEU18484.1 - 7.6e-23 80.4 14.6 3.4e-06 27.7 1.1 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat Nup160 PF11715.8 OEU18484.1 - 5.5e-05 22.0 0.1 0.41 9.2 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OEU18484.1 - 0.002 17.1 0.4 3.7 6.4 0.0 3.3 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Methyltransf_32 PF13679.6 OEU18485.1 - 2.6e-05 24.3 0.2 2.6e-05 24.3 0.2 2.5 3 0 0 3 3 3 1 Methyltransferase domain zf-CCHC PF00098.23 OEU18485.1 - 0.0011 19.0 7.0 0.0021 18.1 7.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Cnd1_N PF12922.7 OEU18485.1 - 0.027 14.3 1.8 0.027 14.3 1.8 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term IMUP PF15761.5 OEU18486.1 - 0.01 16.5 6.1 0.01 16.5 6.1 3.0 3 1 0 3 3 3 0 Immortalisation up-regulated protein RE_TdeIII PF09520.10 OEU18487.1 - 1.4 8.6 7.4 1.1 8.9 0.8 2.3 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII TPX2 PF06886.11 OEU18487.1 - 3.9 7.8 9.4 12 6.2 2.6 3.1 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) FMN_red PF03358.15 OEU18488.1 - 2e-16 60.1 0.0 4.8e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Exostosin PF03016.15 OEU18489.1 - 6.6e-07 28.8 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Sec39 PF08314.11 OEU18489.1 - 0.0051 15.3 0.2 0.0078 14.7 0.2 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 SesA PF17107.5 OEU18489.1 - 0.033 14.4 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ribul_P_3_epim PF00834.19 OEU18490.1 - 1.4e-58 197.6 0.0 1.7e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OEU18490.1 - 0.0046 16.8 0.0 0.014 15.2 0.0 1.9 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 OEU18490.1 - 0.019 14.6 0.1 0.044 13.4 0.1 1.8 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Acyltransf_C PF16076.5 OEU18491.1 - 3.9e-11 42.9 0.4 7.4e-11 42.0 0.4 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 OEU18491.1 - 0.0061 16.2 0.2 0.046 13.3 0.2 2.2 1 1 0 1 1 1 1 Acyltransferase Biotin_lipoyl PF00364.22 OEU18492.1 - 1.6e-16 59.9 2.6 2.8e-16 59.1 2.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 OEU18492.1 - 0.0047 18.5 1.0 0.016 16.8 1.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Biotin_lipoyl_2 PF13533.6 OEU18492.1 - 0.0052 16.6 3.6 0.02 14.7 1.2 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 OEU18492.1 - 0.076 12.9 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2118 PF09891.9 OEU18492.1 - 0.08 12.9 0.1 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Dicty_REP PF05086.12 OEU18492.1 - 0.31 9.0 1.7 0.35 8.8 1.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein APC1_C PF18122.1 OEU18493.1 - 1.9e-17 63.7 0.3 3.1e-17 63.0 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 OEU18493.1 - 0.00024 21.4 0.2 0.038 14.4 0.0 5.0 6 0 0 6 6 6 2 Proteasome/cyclosome repeat ABC_membrane PF00664.23 OEU18494.1 - 3.9e-46 157.9 8.8 5.2e-46 157.5 8.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OEU18494.1 - 1.4e-31 109.8 0.0 2.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU18494.1 - 9.8e-05 21.9 1.8 0.0012 18.4 1.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OEU18494.1 - 0.0003 19.7 0.4 0.00049 19.0 0.4 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 OEU18494.1 - 0.0069 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU18494.1 - 0.02 15.2 0.2 0.21 11.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OEU18494.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 OEU18494.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.6 OEU18494.1 - 0.06 13.6 0.6 0.8 10.0 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 OEU18494.1 - 0.081 12.1 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 OEU18494.1 - 0.097 12.2 0.2 0.89 9.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 OEU18496.1 - 2.5e-18 66.1 13.9 2.5e-18 66.1 13.9 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU18496.1 - 6e-07 28.7 2.4 6e-07 28.7 2.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 OEU18496.1 - 0.001 17.8 2.1 0.0017 17.0 0.4 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein DUF2431 PF10354.9 OEU18498.1 - 1e-22 81.2 0.3 1.9e-22 80.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Peptidase_U57 PF05582.12 OEU18498.1 - 0.057 12.7 4.9 0.19 11.0 2.8 2.2 2 0 0 2 2 2 0 YabG peptidase U57 NAD_binding_7 PF13241.6 OEU18498.1 - 0.1 13.0 0.0 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding FAM176 PF14851.6 OEU18498.1 - 9.3 5.9 23.5 24 4.5 0.5 3.8 3 1 1 4 4 4 0 FAM176 family PPP4R2 PF09184.11 OEU18498.1 - 9.6 5.7 32.6 0.22 11.1 9.8 2.8 3 0 0 3 3 3 0 PPP4R2 CRAL_TRIO PF00650.20 OEU18499.1 - 2.1e-07 30.8 0.0 5.2e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 CRAL/TRIO domain MAP17 PF15807.5 OEU18499.1 - 0.027 14.7 1.0 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Cwf_Cwc_15 PF04889.12 OEU18499.1 - 0.033 13.9 7.8 0.048 13.4 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Corona_nucleoca PF00937.18 OEU18499.1 - 0.11 11.5 6.4 0.16 11.0 6.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ctr PF04145.15 OEU18499.1 - 1.8 9.2 5.2 6 7.5 5.2 2.0 1 1 0 1 1 1 0 Ctr copper transporter family MttA_Hcf106 PF02416.16 OEU18500.1 - 0.12 11.7 0.8 0.43 9.9 0.1 2.4 2 1 0 2 2 2 0 mttA/Hcf106 family Abhydrolase_3 PF07859.13 OEU18501.1 - 1.3e-09 38.2 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU18501.1 - 0.00051 19.6 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DNA_methylase PF00145.17 OEU18502.1 - 3e-55 187.9 0.1 7.7e-54 183.3 0.0 2.6 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase CHAT PF12770.7 OEU18503.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 CHAT domain Hist_deacetyl PF00850.19 OEU18504.1 - 1.5e-32 113.3 0.0 2e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Myb_DNA-binding PF00249.31 OEU18505.1 - 1.6e-12 47.4 0.5 1.8e-12 47.3 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU18505.1 - 3.6e-05 23.9 0.1 4.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU18505.1 - 0.0018 18.2 0.3 0.0023 17.8 0.3 1.3 1 1 0 1 1 1 1 Myb DNA-binding like DUF2726 PF10881.8 OEU18505.1 - 0.048 13.6 0.1 0.056 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) HEAT PF02985.22 OEU18506.1 - 2.3e-26 89.6 20.5 0.023 15.0 0.1 11.4 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.6 OEU18506.1 - 7.2e-19 68.0 4.2 4.6e-07 30.1 0.0 5.3 4 1 1 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 OEU18506.1 - 1.2e-09 38.5 16.0 0.00071 20.0 0.0 7.0 6 3 2 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 OEU18506.1 - 5.4e-06 26.5 2.2 3.2 7.8 0.0 4.9 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OEU18506.1 - 0.0056 16.3 0.0 0.024 14.2 0.0 2.1 2 1 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.20 OEU18506.1 - 0.022 13.4 0.6 17 3.8 0.0 4.0 2 1 0 3 3 3 0 Adaptin N terminal region TFCD_C PF12612.8 OEU18506.1 - 0.054 13.3 1.3 2.4 8.0 0.2 3.0 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 OEU18506.1 - 0.19 12.0 0.7 1.2e+02 3.1 0.8 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion EF1G PF00647.19 OEU18507.1 - 2.5e-09 37.2 0.1 3.7e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain TFIID-18kDa PF02269.16 OEU18507.1 - 0.051 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit ydhR PF08803.11 OEU18507.1 - 0.075 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR GPHH PF16905.5 OEU18507.1 - 0.16 11.8 0.3 22 4.9 0.1 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated L_HMGIC_fpl PF10242.9 OEU18508.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF3341 PF11821.8 OEU18509.1 - 0.15 11.7 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Sec2p PF06428.11 OEU18509.1 - 0.22 11.5 0.6 26 4.9 0.1 2.6 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF4690 PF15756.5 OEU18510.1 - 0.087 13.4 0.2 0.23 12.1 0.2 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage SBBP PF06739.11 OEU18510.1 - 8.9 6.4 10.2 4.5 7.4 0.2 3.6 3 0 0 3 3 3 0 Beta-propeller repeat PPR_2 PF13041.6 OEU18511.1 - 1.8e-17 63.2 4.5 0.0022 18.2 0.0 5.5 5 1 0 5 5 5 5 PPR repeat family PPR_3 PF13812.6 OEU18511.1 - 1.4e-11 44.3 2.6 0.009 16.1 0.0 6.2 4 2 1 5 5 5 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU18511.1 - 4.1e-08 32.8 7.5 0.12 12.1 0.2 6.0 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 OEU18511.1 - 6.8e-08 32.1 0.2 0.0022 17.4 0.0 3.3 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 OEU18511.1 - 0.0037 17.6 1.0 0.38 11.1 0.2 2.5 2 1 1 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) PPR PF01535.20 OEU18511.1 - 0.22 11.9 5.3 24 5.4 0.1 4.9 6 1 0 6 6 6 0 PPR repeat Glyco_transf_41 PF13844.6 OEU18512.1 - 1.2e-16 60.3 0.0 2e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 Glycos_transf_1 PF00534.20 OEU18512.1 - 2.1e-12 46.9 0.0 1.4e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OEU18512.1 - 1.2e-10 41.9 0.0 2.4e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Dimer_Tnp_hAT PF05699.14 OEU18513.1 - 1e-16 60.5 0.0 1.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4312 PF14189.6 OEU18514.1 - 0.22 11.5 8.2 5.9 7.0 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4312) TetR_C_24 PF17932.1 OEU18514.1 - 0.55 10.5 3.2 17 5.7 0.1 3.7 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Trypan_PARP PF05887.11 OEU18514.1 - 7 6.6 12.0 0.67 9.9 7.2 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Epimerase PF01370.21 OEU18515.1 - 1.4e-44 152.4 0.0 1.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU18515.1 - 4e-28 98.8 0.0 2.9e-27 96.0 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU18515.1 - 1.1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OEU18515.1 - 5.1e-06 26.5 0.0 6.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OEU18515.1 - 0.00072 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 OEU18515.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 OEU18515.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OEU18515.1 - 0.027 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.15 OEU18515.1 - 0.031 13.4 0.0 1.6 7.8 0.0 2.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 OEU18515.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OEU18515.1 - 0.043 13.0 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein 3HCDH_N PF02737.18 OEU18515.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 OEU18515.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase VraX PF17412.2 OEU18516.1 - 0.1 12.2 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function Fea1 PF07692.11 OEU18517.1 - 1.8e-05 24.0 5.0 0.0073 15.4 1.2 3.0 2 1 0 2 2 2 2 Low iron-inducible periplasmic protein DUF2062 PF09835.9 OEU18517.1 - 0.0073 16.2 1.1 0.017 15.0 1.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Baculo_LEF5 PF04838.12 OEU18517.1 - 0.16 12.0 0.9 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 Myosin_head PF00063.21 OEU18518.1 - 2e-174 581.5 3.0 2e-174 581.5 3.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 OEU18518.1 - 2.4e-06 26.8 12.0 0.33 10.9 0.0 4.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif Rad17 PF03215.15 OEU18518.1 - 0.003 17.5 1.1 0.023 14.6 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 OEU18518.1 - 0.021 15.2 0.0 0.021 15.2 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OEU18518.1 - 0.048 14.2 0.0 0.048 14.2 0.0 2.9 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 OEU18518.1 - 0.062 13.6 0.0 0.062 13.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain Peptidase_C1 PF00112.23 OEU18519.1 - 1.8e-68 230.9 0.4 2.6e-68 230.4 0.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OEU18519.1 - 2.7e-14 53.3 0.3 9.8e-14 51.5 0.5 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OEU18519.1 - 3.1e-05 22.9 0.3 0.041 12.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Mpv17_PMP22 PF04117.12 OEU18520.1 - 7.7e-16 58.1 1.1 7.7e-16 58.1 1.1 1.9 3 0 0 3 3 3 1 Mpv17 / PMP22 family RVT_1 PF00078.27 OEU18521.1 - 1.3e-06 28.1 0.0 4.4e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU18521.1 - 0.012 16.3 0.7 0.049 14.3 0.7 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Transketolase_C PF02780.20 OEU18521.1 - 0.17 11.8 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 Transketolase, C-terminal domain DUF305 PF03713.13 OEU18522.1 - 1.7e-09 38.0 0.1 7e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF305) ABC_tran PF00005.27 OEU18523.1 - 3.2e-46 157.2 0.2 2.7e-25 89.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OEU18523.1 - 6.9e-16 58.9 9.5 8.5e-08 32.3 0.0 4.7 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OEU18523.1 - 4.3e-14 52.3 0.8 4.3e-14 52.3 0.8 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OEU18523.1 - 3.3e-07 30.0 4.6 0.098 12.1 0.0 4.4 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 OEU18523.1 - 1e-06 28.8 4.0 1e-06 28.8 4.0 2.2 2 0 0 2 2 2 1 ABC transporter C-terminal domain AAA_18 PF13238.6 OEU18523.1 - 1.8e-05 25.3 2.2 0.064 13.8 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 OEU18523.1 - 3.4e-05 24.3 0.1 0.18 12.2 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OEU18523.1 - 3.9e-05 23.3 0.1 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU18523.1 - 5.9e-05 23.0 2.7 0.092 12.6 0.1 3.0 3 0 0 3 3 3 2 RsgA GTPase TsaE PF02367.17 OEU18523.1 - 6.5e-05 22.9 0.1 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OEU18523.1 - 7.9e-05 23.0 0.4 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OEU18523.1 - 9.8e-05 22.6 0.2 0.45 10.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OEU18523.1 - 0.00011 22.0 1.2 0.39 10.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 OEU18523.1 - 0.00017 22.0 0.3 0.71 10.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase MMR_HSR1 PF01926.23 OEU18523.1 - 0.00036 20.6 1.4 0.52 10.4 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 OEU18523.1 - 0.00037 20.3 10.7 0.018 14.8 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 OEU18523.1 - 0.00058 20.3 0.0 2.2 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 OEU18523.1 - 0.00082 19.0 0.5 2 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 OEU18523.1 - 0.0013 18.7 0.4 1.2 9.1 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 OEU18523.1 - 0.0058 16.4 2.7 1.2 8.8 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OEU18523.1 - 0.0061 16.6 0.1 6.2 6.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 OEU18523.1 - 0.0064 16.2 0.1 1 8.9 0.0 2.5 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 OEU18523.1 - 0.0078 16.1 0.9 0.66 9.9 0.2 3.1 2 0 0 2 2 2 1 NTPase DUF3637 PF12337.8 OEU18523.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) AAA_33 PF13671.6 OEU18523.1 - 0.015 15.4 0.1 8.9 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU18523.1 - 0.02 14.4 0.7 0.94 9.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Acid_PPase PF12689.7 OEU18523.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase PduV-EutP PF10662.9 OEU18523.1 - 0.025 14.3 0.4 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OEU18523.1 - 0.031 13.5 0.1 0.5 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 OEU18523.1 - 0.056 13.5 0.1 17 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 OEU18523.1 - 0.066 13.0 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 OEU18523.1 - 0.12 12.9 17.1 0.31 11.5 0.0 3.7 4 1 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 OEU18523.1 - 0.14 11.4 2.1 0.89 8.8 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin dNK PF01712.19 OEU18523.1 - 0.15 11.9 3.0 2.8 7.7 0.3 2.7 3 0 0 3 3 2 0 Deoxynucleoside kinase Roc PF08477.13 OEU18523.1 - 0.15 12.2 3.3 5.7 7.2 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 OEU18523.1 - 0.21 11.2 1.2 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FeoB_N PF02421.18 OEU18523.1 - 0.22 11.0 0.7 55 3.3 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B UPF0242 PF06785.11 OEU18523.1 - 0.3 11.2 2.9 0.28 11.3 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 OEU18523.1 - 1.1 7.8 9.3 4 5.9 0.2 3.9 4 1 0 4 4 4 0 AAA domain DUF87 PF01935.17 OEU18523.1 - 2 8.5 13.9 12 6.0 0.2 4.4 5 0 0 5 5 4 0 Helicase HerA, central domain DUF2353 PF09789.9 OEU18523.1 - 4 6.7 11.0 0.56 9.5 3.7 2.2 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) AAA_2 PF07724.14 OEU18524.1 - 8.1e-51 172.5 0.7 3.3e-49 167.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OEU18524.1 - 1.1e-27 97.1 0.0 4.5e-14 53.0 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_9 PF17871.1 OEU18524.1 - 5.1e-25 87.4 0.0 1.2e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 OEU18524.1 - 8.5e-17 61.4 0.0 1.1e-10 41.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 OEU18524.1 - 2.9e-14 52.9 0.2 8.2e-14 51.4 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 OEU18524.1 - 6.9e-14 52.6 0.5 2.9e-05 24.5 0.1 4.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OEU18524.1 - 4.2e-13 49.7 0.6 0.00018 21.8 1.2 3.9 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 OEU18524.1 - 5.1e-11 42.6 0.0 5.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 OEU18524.1 - 2.6e-07 30.3 0.0 0.0061 16.1 0.0 3.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_18 PF13238.6 OEU18524.1 - 5.1e-07 30.3 0.0 0.022 15.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 OEU18524.1 - 5.5e-07 29.2 0.0 0.0037 16.7 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 OEU18524.1 - 1.3e-06 28.4 0.0 0.013 15.6 0.0 3.3 2 1 0 3 3 3 2 AAA domain RuvB_N PF05496.12 OEU18524.1 - 2.8e-06 27.2 0.9 1.8 8.3 0.0 3.9 3 1 1 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OEU18524.1 - 3.7e-06 26.8 0.0 0.081 12.6 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 OEU18524.1 - 0.00015 21.6 0.0 0.13 12.2 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OEU18524.1 - 0.00017 21.8 0.0 0.18 12.0 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OEU18524.1 - 0.00022 21.6 0.0 0.14 12.5 0.0 3.1 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 OEU18524.1 - 0.00028 20.9 0.0 21 4.9 0.0 4.5 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OEU18524.1 - 0.00033 20.8 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 OEU18524.1 - 0.0004 20.4 0.0 1.2 9.1 0.0 3.7 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 OEU18524.1 - 0.00069 18.9 0.0 0.1 11.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 OEU18524.1 - 0.001 19.1 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OEU18524.1 - 0.0026 17.2 0.1 3.1 7.1 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OEU18524.1 - 0.0055 17.1 0.0 3.8 7.9 0.0 3.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OEU18524.1 - 0.0065 16.4 0.4 14 5.6 0.0 4.2 4 0 0 4 4 4 0 NTPase NACHT PF05729.12 OEU18524.1 - 0.0067 16.4 0.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain MCM PF00493.23 OEU18524.1 - 0.007 15.5 0.0 2.8 7.0 0.0 3.2 2 1 0 2 2 2 1 MCM P-loop domain RsgA_GTPase PF03193.16 OEU18524.1 - 0.013 15.4 0.0 0.59 10.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 OEU18524.1 - 0.015 15.1 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OEU18524.1 - 0.021 14.5 0.1 0.24 11.0 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OEU18524.1 - 0.031 14.0 0.1 6.7 6.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 OEU18524.1 - 0.034 13.3 0.2 2.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 OEU18524.1 - 0.081 12.7 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_28 PF13521.6 OEU18524.1 - 0.09 13.0 0.0 8.2 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OEU18524.1 - 0.1 12.9 0.3 14 6.0 0.0 4.0 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 OEU18524.1 - 0.12 12.9 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Torsin PF06309.11 OEU18524.1 - 0.16 12.1 0.0 0.66 10.1 0.0 2.0 2 0 0 2 2 1 0 Torsin Sar8_2 PF03058.14 OEU18524.1 - 0.19 12.3 0.1 0.46 11.0 0.1 1.6 1 0 0 1 1 1 0 Sar8.2 family ANAPC1 PF12859.7 OEU18525.1 - 0.04 14.5 1.9 0.049 14.2 1.9 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 LSM PF01423.22 OEU18525.1 - 0.058 13.1 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 LSM domain bZIP_2 PF07716.15 OEU18525.1 - 0.086 12.9 0.4 0.086 12.9 0.4 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DUF948 PF06103.11 OEU18525.1 - 0.11 12.7 0.4 0.18 12.1 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BssS PF13991.6 OEU18525.1 - 0.15 12.2 0.2 0.73 9.9 0.1 1.9 2 0 0 2 2 2 0 BssS protein family Myosin_head PF00063.21 OEU18527.1 - 1.5e-183 611.7 0.2 1.5e-183 611.7 0.2 2.7 3 1 0 3 3 3 1 Myosin head (motor domain) IQ PF00612.27 OEU18527.1 - 5.1e-06 25.8 9.3 0.034 13.9 1.4 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif AAA_22 PF13401.6 OEU18527.1 - 0.085 13.1 0.3 0.9 9.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU18527.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.6 OEU18527.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain TMEM192 PF14802.6 OEU18527.1 - 7.3 5.6 7.6 24 3.9 3.9 2.8 3 0 0 3 3 3 0 TMEM192 family NUDIX PF00293.28 OEU18528.1 - 5e-05 23.3 0.0 0.00032 20.7 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain RRM_1 PF00076.22 OEU18529.1 - 1.1e-19 70.1 0.0 1.2e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU18529.1 - 0.00028 20.9 0.0 0.00049 20.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif DUF4140 PF13600.6 OEU18529.1 - 0.0008 19.8 0.0 0.00093 19.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) RRM_3 PF08777.11 OEU18529.1 - 0.056 13.5 0.1 0.075 13.1 0.1 1.3 1 1 0 1 1 1 0 RNA binding motif LRR_8 PF13855.6 OEU18530.1 - 3.8e-14 52.2 15.0 1.1e-09 37.9 3.1 4.7 2 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OEU18530.1 - 5.9e-13 48.8 16.2 0.0023 18.3 0.1 5.6 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU18530.1 - 1.4e-05 25.0 12.2 1.1 10.1 0.5 7.2 6 3 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU18530.1 - 9.3 6.6 15.5 4.9 7.5 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich repeat Glycolytic PF00274.19 OEU18531.1 - 8.9e-150 498.2 0.0 1e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Flavokinase PF01687.17 OEU18533.1 - 8.8e-28 96.8 0.0 1.1e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase ABC_tran PF00005.27 OEU18534.1 - 5.5e-25 88.5 0.0 6.9e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 OEU18534.1 - 5.4e-05 23.8 0.1 7.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OEU18534.1 - 9.9e-05 22.3 0.2 0.00016 21.6 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 OEU18534.1 - 0.00097 19.0 0.8 0.89 9.3 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OEU18534.1 - 0.0028 17.7 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OEU18534.1 - 0.0033 17.1 0.4 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DLIC PF05783.11 OEU18534.1 - 0.0066 15.3 0.1 0.0093 14.8 0.1 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) SMC_N PF02463.19 OEU18534.1 - 0.01 15.3 0.2 0.43 10.0 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OEU18534.1 - 0.013 15.8 0.1 0.021 15.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OEU18534.1 - 0.014 15.7 2.6 0.41 10.9 2.6 2.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OEU18534.1 - 0.041 13.9 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family cobW PF02492.19 OEU18534.1 - 0.046 13.3 0.2 0.081 12.5 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OEU18534.1 - 0.06 13.6 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 OEU18534.1 - 0.062 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OEU18534.1 - 0.073 13.5 0.1 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU18534.1 - 0.073 12.6 1.8 0.59 9.7 1.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OEU18534.1 - 0.079 13.2 0.5 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 OEU18534.1 - 0.13 11.0 1.0 9.9 4.8 1.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 OEU18534.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OEU18534.1 - 0.21 11.3 0.7 0.4 10.4 0.7 1.4 1 0 0 1 1 1 0 AAA domain CRAL_TRIO PF00650.20 OEU18535.1 - 0.13 12.0 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 CRAL/TRIO domain PALP PF00291.25 OEU18536.1 - 8.3e-67 225.7 0.4 9.6e-67 225.5 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cons_hypoth698 PF03601.14 OEU18536.1 - 0.025 13.5 0.2 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 698 RNA_pol_Rpb1_5 PF04998.17 OEU18537.1 - 3.6e-95 318.4 0.0 6.4e-95 317.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OEU18537.1 - 1e-75 255.0 0.0 2e-75 254.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OEU18537.1 - 5e-72 241.5 0.0 1.1e-71 240.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OEU18537.1 - 1.3e-56 191.5 0.0 2.4e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OEU18537.1 - 9.9e-43 145.8 0.0 3.3e-42 144.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OEU18537.1 - 6.9e-40 136.2 3.7 2.2e-39 134.6 3.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OEU18537.1 - 4e-37 126.5 0.2 1e-36 125.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OEU18537.1 - 8.3e-12 44.8 119.9 0.013 15.8 12.7 6.8 6 0 0 6 6 6 6 RNA polymerase Rpb1 C-terminal repeat Exostosin PF03016.15 OEU18538.1 - 2.5e-22 79.5 0.0 1.1e-21 77.3 0.0 2.1 1 1 0 1 1 1 1 Exostosin family PTR2 PF00854.21 OEU18538.1 - 0.16 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 POT family GHMP_kinases_N PF00288.26 OEU18538.1 - 0.31 11.3 2.4 0.67 10.2 2.4 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain GCP_C_terminal PF04130.13 OEU18539.1 - 9.3e-56 189.5 6.0 9.9e-56 189.5 4.9 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OEU18539.1 - 5.3e-53 180.6 0.1 1.2e-52 179.4 0.1 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Ank_2 PF12796.7 OEU18540.1 - 1.9e-31 108.5 0.4 3.5e-09 37.1 0.0 7.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU18540.1 - 2.1e-25 86.0 4.4 0.0087 16.5 0.0 12.1 12 0 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 OEU18540.1 - 3.3e-23 81.0 3.0 0.0062 16.9 0.0 11.4 12 0 0 12 12 12 4 Ankyrin repeat Ank_4 PF13637.6 OEU18540.1 - 4.6e-20 71.7 7.6 0.00071 20.1 0.0 9.3 6 3 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU18540.1 - 1.3e-12 47.7 12.7 0.0065 16.8 0.2 10.1 6 2 5 11 11 11 6 Ankyrin repeats (many copies) Sulfotransfer_4 PF17784.1 OEU18540.1 - 0.082 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Sulfotransferase domain Inositol_P PF00459.25 OEU18541.1 - 5e-13 49.2 2.5 2e-09 37.4 0.4 2.1 1 1 1 2 2 2 2 Inositol monophosphatase family DUF3482 PF11981.8 OEU18541.1 - 0.01 15.2 0.5 0.014 14.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) FBPase PF00316.20 OEU18541.1 - 0.046 13.2 1.2 0.087 12.3 0.7 1.6 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OEU18542.1 - 3.8e-08 33.2 0.0 4.2e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TPR_1 PF00515.28 OEU18543.1 - 1.4e-25 88.0 23.1 1.2e-05 24.9 0.7 6.7 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU18543.1 - 2.1e-21 74.2 19.1 8.1e-06 25.6 0.7 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OEU18543.1 - 4.7e-20 71.0 4.3 7.8e-07 28.7 0.1 5.5 3 2 2 5 5 5 3 TPR repeat STI1 PF17830.1 OEU18543.1 - 1.8e-14 53.4 3.9 1.8e-14 53.4 3.9 2.0 2 0 0 2 2 2 1 STI1 domain TPR_14 PF13428.6 OEU18543.1 - 4.6e-14 51.9 1.2 0.043 14.6 0.0 6.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU18543.1 - 1.7e-11 44.3 3.9 0.00036 20.8 0.0 4.7 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU18543.1 - 3.5e-11 42.7 2.6 0.31 11.5 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OEU18543.1 - 4e-11 43.4 3.4 0.0017 19.0 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU18543.1 - 5.9e-09 35.4 26.4 0.34 11.2 0.5 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OEU18543.1 - 2.6e-08 34.3 10.5 0.0063 17.0 0.1 4.7 2 2 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU18543.1 - 0.0019 18.2 3.9 6 7.0 0.0 4.6 4 1 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 OEU18543.1 - 0.0059 16.7 0.0 4.7 7.4 0.0 3.7 2 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU18543.1 - 0.0076 16.5 1.5 0.0076 16.5 1.5 3.4 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OEU18543.1 - 0.014 15.3 4.5 36 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU18543.1 - 0.024 14.5 17.6 0.59 10.1 0.2 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Thiolase_N PF00108.23 OEU18543.1 - 0.072 12.4 2.4 0.11 11.9 1.1 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain TPR_3 PF07720.12 OEU18543.1 - 4.6 7.3 12.2 10 6.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Got1 PF04178.12 OEU18544.1 - 1.5e-16 60.8 10.6 1.9e-16 60.4 10.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Fzo_mitofusin PF04799.13 OEU18544.1 - 0.28 10.7 0.4 0.38 10.3 0.4 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF2157 PF09925.9 OEU18544.1 - 1.2 8.9 12.0 6.4 6.6 11.9 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF3185 PF11381.8 OEU18544.1 - 4.1 7.5 17.8 1.8 8.7 2.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3185) DSBA PF01323.20 OEU18545.1 - 3.9e-05 23.5 0.0 0.00013 21.8 0.0 1.8 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Ank_2 PF12796.7 OEU18546.1 - 2.6e-11 43.9 0.2 0.2 12.3 0.0 6.4 6 1 1 7 7 7 3 Ankyrin repeats (3 copies) Ank PF00023.30 OEU18546.1 - 1.4e-08 34.8 3.8 0.74 10.4 0.1 6.7 8 0 0 8 8 8 2 Ankyrin repeat Ank_3 PF13606.6 OEU18546.1 - 2.4e-08 33.6 0.3 6 7.8 0.0 6.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OEU18546.1 - 1.8e-07 31.3 4.7 0.58 10.6 0.4 6.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU18546.1 - 3.7e-06 27.4 0.1 0.91 10.2 0.1 5.5 4 2 1 5 5 5 2 Ankyrin repeats (many copies) CSG2 PF16965.5 OEU18546.1 - 1.6 7.6 6.1 0.85 8.5 1.2 2.8 3 0 0 3 3 3 0 Ceramide synthase regulator CENP-B_dimeris PF09026.10 OEU18546.1 - 2.1 8.8 23.4 0.66 10.4 0.1 4.6 5 0 0 5 5 5 0 Centromere protein B dimerisation domain Lipoxygenase PF00305.19 OEU18547.1 - 1.3e-12 47.0 0.2 4.7e-05 22.0 0.2 2.5 2 1 0 2 2 2 2 Lipoxygenase Sacchrp_dh_NADP PF03435.18 OEU18548.1 - 1.1e-16 61.3 0.0 1.7e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 OEU18548.1 - 1.7e-05 24.8 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OEU18548.1 - 0.00027 21.4 0.1 0.0017 18.8 0.0 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 OEU18548.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase PF01370.21 OEU18548.1 - 0.0026 17.2 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OEU18548.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 OEU18548.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pdase_C33_assoc PF14756.6 OEU18548.1 - 0.016 15.2 0.1 0.031 14.2 0.1 1.6 1 1 0 1 1 1 0 Peptidase_C33-associated domain NmrA PF05368.13 OEU18548.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 2-ph_phosp PF04029.14 OEU18548.1 - 0.17 11.0 0.3 4.6 6.4 0.1 2.3 1 1 1 2 2 2 0 2-phosphosulpholactate phosphatase Ank_2 PF12796.7 OEU18549.1 - 3.7e-17 62.7 0.0 8e-15 55.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU18549.1 - 1.7e-15 57.2 0.4 2.9e-11 43.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU18549.1 - 2.9e-14 52.9 0.9 1.3e-06 28.5 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU18549.1 - 5.6e-11 41.7 0.0 6.7e-06 26.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OEU18549.1 - 2e-08 34.3 0.0 0.0027 18.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat DUF1815 PF08844.10 OEU18549.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Sulfotransfer_1 PF00685.27 OEU18550.1 - 6.2e-21 75.1 0.0 9.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU18550.1 - 1.6e-06 28.7 0.2 0.00033 21.1 0.0 2.6 1 1 1 2 2 2 2 Sulfotransferase family FAM83 PF07894.12 OEU18550.1 - 0.014 14.9 0.3 0.45 10.0 0.1 2.2 2 0 0 2 2 2 0 FAM83 A-H Sulfotransfer_4 PF17784.1 OEU18550.1 - 0.079 12.8 0.0 0.41 10.4 0.0 2.4 1 1 0 1 1 1 0 Sulfotransferase domain PPR PF01535.20 OEU18551.1 - 1.5e-14 53.1 4.4 0.014 15.6 0.0 6.4 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 OEU18551.1 - 2.8e-10 40.2 0.6 0.09 13.0 0.0 5.7 6 0 0 6 6 6 2 PPR repeat family PPR_1 PF12854.7 OEU18551.1 - 1.7e-05 24.4 0.2 0.036 13.8 0.0 3.5 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 OEU18551.1 - 0.0031 16.9 0.6 0.13 11.6 0.1 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 OEU18551.1 - 0.036 13.9 3.0 0.54 10.1 0.1 3.3 4 0 0 4 4 4 0 Region in Clathrin and VPS TIP120 PF08623.10 OEU18551.1 - 0.038 13.8 0.5 0.079 12.7 0.5 1.5 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Xpo1 PF08389.12 OEU18551.1 - 0.24 11.4 4.0 0.19 11.8 0.3 2.5 3 0 0 3 3 3 0 Exportin 1-like protein PPR_2 PF13041.6 OEU18552.1 - 2.4e-05 24.4 0.2 3.3 8.0 0.0 5.6 5 1 0 5 5 5 2 PPR repeat family RPM2 PF08579.11 OEU18552.1 - 0.0022 18.4 8.8 0.0024 18.3 1.0 4.6 3 2 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_3 PF13812.6 OEU18552.1 - 0.0054 16.8 2.3 0.7 10.0 0.3 3.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain Sad1_UNC PF07738.13 OEU18553.1 - 2.1e-24 86.0 0.0 8.2e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal BAR_3 PF16746.5 OEU18553.1 - 0.031 14.0 5.6 0.047 13.4 5.6 1.2 1 0 0 1 1 1 0 BAR domain of APPL family RPW8 PF05659.11 OEU18553.1 - 0.08 12.6 5.1 0.96 9.1 1.9 2.5 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AraC_N PF06719.13 OEU18553.1 - 0.16 11.6 1.0 0.32 10.6 1.0 1.5 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus DUF4208 PF13907.6 OEU18553.1 - 0.18 12.3 1.0 0.6 10.6 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) SOAR PF16533.5 OEU18553.1 - 0.18 11.8 5.8 2.7 8.0 4.7 2.6 1 1 1 2 2 2 0 STIM1 Orai1-activating region Z1 PF10593.9 OEU18553.1 - 0.34 10.4 2.3 0.6 9.6 2.3 1.5 1 0 0 1 1 1 0 Z1 domain FAM76 PF16046.5 OEU18553.1 - 0.4 10.0 5.9 0.71 9.2 5.9 1.3 1 0 0 1 1 1 0 FAM76 protein Mod_r PF07200.13 OEU18553.1 - 0.66 10.1 14.4 55 3.9 14.4 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TINF2_N PF14973.6 OEU18553.1 - 1.7 9.0 4.1 7.8 6.8 0.1 2.4 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF1843 PF08898.10 OEU18553.1 - 2.4 8.7 4.1 1.5 9.4 1.1 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) Syntaxin-6_N PF09177.11 OEU18553.1 - 3.1 8.4 9.1 6.3 7.4 8.0 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF745 PF05335.13 OEU18553.1 - 4.1 7.1 6.2 8.5 6.0 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ACR_tran PF00873.19 OEU18553.1 - 4.4 4.8 10.4 3 5.4 5.9 1.9 1 1 1 2 2 2 0 AcrB/AcrD/AcrF family Flagellin_N PF00669.20 OEU18553.1 - 5.8 7.0 15.4 0.22 11.6 1.2 3.2 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region LUC7 PF03194.15 OEU18553.1 - 6 6.5 10.0 42 3.7 8.6 2.5 1 1 1 2 2 2 0 LUC7 N_terminus Syntaxin_2 PF14523.6 OEU18553.1 - 8.4 6.8 18.5 0.34 11.3 2.9 3.3 2 1 1 3 3 3 0 Syntaxin-like protein DUF2203 PF09969.9 OEU18553.1 - 9.6 7.0 6.9 18 6.0 5.5 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MAD PF05557.13 OEU18554.1 - 5.4e-21 74.6 9.4 5.4e-21 74.6 9.4 3.1 1 1 1 2 2 2 1 Mitotic checkpoint protein IKKbetaNEMObind PF12179.8 OEU18554.1 - 0.92 9.6 4.7 2.5 8.2 1.7 3.4 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain DASH_Duo1 PF08651.10 OEU18554.1 - 1.2 8.9 10.3 0.1 12.4 0.7 3.8 4 1 0 4 4 4 0 DASH complex subunit Duo1 Sec34 PF04136.15 OEU18554.1 - 2.5 8.0 15.8 1.4 8.8 2.5 3.8 3 1 0 3 3 3 0 Sec34-like family DUF1445 PF07286.12 OEU18555.1 - 5e-59 198.3 0.1 6.6e-59 198.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) NRD1_2 PF01995.16 OEU18555.1 - 0.00058 19.2 0.0 0.32 10.2 0.0 2.2 1 1 1 2 2 2 2 NrpR regulatory domains NRD1 and 2 FerI PF08151.12 OEU18555.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 FerI (NUC094) domain AAR2 PF05282.11 OEU18556.1 - 1.3 8.4 4.9 0.71 9.2 3.3 1.3 1 1 0 1 1 1 0 AAR2 protein SAP PF02037.27 OEU18557.1 - 1.5e-13 50.2 1.7 2.1e-13 49.7 1.7 1.2 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 OEU18557.1 - 0.0011 18.6 0.3 0.004 16.8 0.3 1.9 1 1 0 1 1 1 1 HeH/LEM domain UIM PF02809.20 OEU18558.1 - 0.04 13.8 1.2 0.076 13.0 1.2 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif FAIM1 PF06905.13 OEU18558.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) CDC45 PF02724.14 OEU18560.1 - 0.0013 17.2 7.0 0.0018 16.7 7.0 1.2 1 0 0 1 1 1 1 CDC45-like protein DDDD PF10161.9 OEU18560.1 - 0.28 11.0 0.0 0.28 11.0 0.0 3.6 3 0 0 3 3 3 0 Putative mitochondrial precursor protein EphA2_TM PF14575.6 OEU18560.1 - 3.9 8.4 5.7 17 6.4 0.0 3.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain YL1 PF05764.13 OEU18560.1 - 6.9 6.7 14.6 11 6.1 14.2 1.5 1 1 0 1 1 1 0 YL1 nuclear protein DUF2448 PF10476.9 OEU18560.1 - 7.7 6.3 6.5 0.45 10.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Methyltransf_4 PF02390.17 OEU18562.1 - 1.5e-32 112.4 0.0 9.3e-32 109.9 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 OEU18562.1 - 0.00012 21.8 0.0 0.00029 20.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU18562.1 - 0.00017 22.2 0.0 0.00037 21.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU18562.1 - 0.0035 17.2 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU18562.1 - 0.0085 16.7 0.0 0.018 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU18562.1 - 0.0087 16.8 0.0 0.017 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Es2 PF09751.9 OEU18563.1 - 1e-20 74.9 23.2 9.5e-20 71.7 23.2 2.3 1 1 0 1 1 1 1 Nuclear protein Es2 SUIM_assoc PF16619.5 OEU18564.1 - 0.9 9.7 6.1 0.34 11.0 2.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Proteasome PF00227.26 OEU18565.1 - 5.3e-50 169.6 0.2 6.9e-50 169.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU18565.1 - 1.3e-14 53.5 0.1 3.2e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AIM24 PF01987.17 OEU18566.1 - 2.2e-58 197.4 1.8 3e-58 196.9 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DAGAT PF03982.13 OEU18567.1 - 2.2e-33 115.5 0.0 2.8e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UPF0054 PF02130.17 OEU18568.1 - 3.3e-32 111.0 1.3 1.6e-17 63.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0054 Glutaredoxin2_C PF04399.13 OEU18569.1 - 4.9e-27 94.3 0.0 7.5e-18 64.6 0.0 2.2 2 0 0 2 2 2 2 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 OEU18569.1 - 1.3e-07 31.9 0.0 4.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU18569.1 - 0.0014 18.8 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU18569.1 - 0.01 16.1 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin bZIP_1 PF00170.21 OEU18571.1 - 3.8e-10 39.7 11.1 6.2e-10 39.0 11.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU18571.1 - 2.8e-07 30.5 10.7 4.7e-07 29.8 10.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU18571.1 - 8e-05 23.1 7.6 0.00012 22.5 7.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 OEU18571.1 - 0.0015 18.7 1.8 0.0031 17.7 1.8 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Taxilin PF09728.9 OEU18571.1 - 0.0015 17.8 1.5 0.0021 17.3 1.5 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Atg14 PF10186.9 OEU18571.1 - 0.011 14.8 2.6 0.013 14.6 2.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GIT_CC PF16559.5 OEU18571.1 - 0.039 13.8 0.6 0.14 12.1 0.5 2.0 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OEU18571.1 - 0.055 14.1 4.1 0.054 14.1 2.3 1.9 1 1 1 2 2 2 0 Initiation control protein YabA GvpL_GvpF PF06386.11 OEU18571.1 - 0.15 12.0 1.5 0.17 11.8 1.5 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4239 PF14023.6 OEU18571.1 - 0.19 11.5 1.2 0.28 10.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CorA PF01544.18 OEU18571.1 - 0.39 10.0 4.6 0.47 9.7 4.6 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PUL PF08324.11 OEU18572.1 - 1.6e-31 109.6 1.5 2.7e-31 108.8 1.5 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OEU18572.1 - 1.3e-25 89.9 0.8 3.1e-25 88.6 0.8 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OEU18572.1 - 2.4e-18 66.1 6.7 5.3e-06 27.1 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU18572.1 - 4.6e-06 26.8 0.2 6.4 7.2 0.0 5.5 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SBD PF17882.1 OEU18572.1 - 0.0019 18.0 1.4 0.27 11.1 0.0 2.7 2 0 0 2 2 2 2 OAA-family lectin sugar binding domain PsbX PF06596.11 OEU18573.1 - 5.8 7.0 7.9 0.28 11.2 1.0 2.5 2 1 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Sulfotransfer_2 PF03567.14 OEU18574.1 - 9.7e-05 22.4 1.9 0.0002 21.4 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase family Pkinase_Tyr PF07714.17 OEU18575.1 - 5.7e-27 94.6 0.0 6.5e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU18575.1 - 2.8e-23 82.6 0.0 3.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU18575.1 - 0.0065 15.3 0.0 0.008 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OEU18575.1 - 0.024 14.5 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cu2_monoox_C PF03712.15 OEU18576.1 - 1.3e-16 60.5 0.5 2.4e-16 59.7 0.5 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Acyl_transf_3 PF01757.22 OEU18576.1 - 3.9e-15 55.8 26.6 7.5e-15 54.8 26.6 1.5 1 0 0 1 1 1 1 Acyltransferase family Cu2_monooxygen PF01082.20 OEU18576.1 - 7.4e-07 29.5 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF3877 PF12993.7 OEU18576.1 - 0.033 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) RNase_T PF00929.24 OEU18577.1 - 4.5e-16 59.8 0.0 5.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OEU18577.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease TPR_12 PF13424.6 OEU18577.1 - 0.049 13.9 0.1 0.077 13.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1882 PF08966.11 OEU18577.1 - 0.1 12.9 0.5 9.9 6.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1882) Band_7 PF01145.25 OEU18578.1 - 9.2e-30 104.0 0.1 9.2e-30 104.0 0.1 2.6 2 1 0 3 3 3 1 SPFH domain / Band 7 family Band_7_C PF16200.5 OEU18578.1 - 7.5e-12 45.1 2.2 1.9e-11 43.9 2.2 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Phage_spike PF18715.1 OEU18578.1 - 0.065 13.3 2.6 0.41 10.7 3.4 2.0 2 0 0 2 2 2 0 Phage spike trimer Peptidase_S9 PF00326.21 OEU18579.1 - 0.0037 16.8 0.0 0.0045 16.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family SOP4 PF17081.5 OEU18579.1 - 0.031 13.8 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein IF4E PF01652.18 OEU18580.1 - 0.29 10.9 1.0 0.5 10.1 1.0 1.5 1 1 0 1 1 1 0 Eukaryotic initiation factor 4E Patched PF02460.18 OEU18581.1 - 1.7e-13 49.6 26.3 9e-08 30.7 11.3 3.9 4 0 0 4 4 4 3 Patched family Sterol-sensing PF12349.8 OEU18581.1 - 1.7e-05 24.7 16.8 0.011 15.6 0.3 3.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation DUF2207 PF09972.9 OEU18581.1 - 0.095 11.4 27.7 0.026 13.3 0.3 5.1 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OEU18581.1 - 0.45 10.8 0.0 0.45 10.8 0.0 5.2 6 0 0 6 6 6 0 Orf78 (ac78) CitMHS PF03600.16 OEU18581.1 - 0.59 9.3 8.8 2.7 7.1 0.3 3.1 2 1 0 2 2 2 0 Citrate transporter ACR_tran PF00873.19 OEU18581.1 - 0.75 7.4 4.3 0.16 9.6 0.3 1.7 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family MtN3_slv PF03083.16 OEU18582.1 - 1.2e-27 95.8 8.1 9.1e-18 64.1 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange C2 PF00168.30 OEU18583.1 - 1.1e-20 73.8 0.0 7.1e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain Chloroa_b-bind PF00504.21 OEU18584.1 - 3.9e-08 34.0 0.2 0.00047 20.7 0.0 2.1 1 1 0 2 2 2 2 Chlorophyll A-B binding protein GTP_CH_N PF12471.8 OEU18585.1 - 3e-78 262.0 0.0 4.1e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OEU18585.1 - 5.9e-15 55.2 0.0 9.8e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Macoilin PF09726.9 OEU18586.1 - 0.31 9.6 6.5 0.39 9.2 6.5 1.2 1 0 0 1 1 1 0 Macoilin family Ribosomal_S4e PF00900.20 OEU18587.1 - 2.3e-31 107.5 0.1 5.2e-31 106.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 OEU18587.1 - 1.4e-22 79.1 0.2 3.2e-22 77.9 0.2 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OEU18587.1 - 1.1e-18 67.0 10.4 2.4e-18 65.9 10.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 OEU18587.1 - 8.2e-09 35.0 0.0 1.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S13_N PF08069.12 OEU18588.1 - 1.1e-31 108.6 0.1 2.1e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OEU18588.1 - 5.1e-15 55.5 1.1 7.5e-15 54.9 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 SecA_DEAD PF07517.14 OEU18590.1 - 1.3e-110 369.3 0.4 2.7e-110 368.2 0.4 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 OEU18590.1 - 3.4e-39 135.0 1.4 3.4e-39 135.0 1.4 2.5 4 0 0 4 4 4 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 OEU18590.1 - 7.9e-25 87.7 0.0 5.4e-24 85.0 0.0 2.5 3 0 0 3 3 3 1 SecA preprotein cross-linking domain DEAD PF00270.29 OEU18590.1 - 7.1e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU18590.1 - 0.05 13.9 0.5 3.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DUF1664 PF07889.12 OEU18590.1 - 9.5 6.3 6.7 1.3 9.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) PDZ_6 PF17820.1 OEU18591.1 - 6e-13 48.4 0.0 5.4e-07 29.4 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 OEU18591.1 - 1.5e-09 38.0 0.0 2.7e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OEU18591.1 - 2e-09 37.6 0.0 0.0011 19.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PHD PF00628.29 OEU18591.1 - 0.0027 17.5 16.7 0.0027 17.5 16.7 4.3 4 0 0 4 4 4 2 PHD-finger DUF3391 PF11871.8 OEU18591.1 - 0.81 10.2 3.1 2.3 8.8 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) LETM1 PF07766.13 OEU18592.1 - 6.5e-94 314.2 4.9 9.5e-94 313.7 4.9 1.2 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 OEU18592.1 - 0.026 14.3 1.1 0.041 13.6 0.1 1.9 2 0 0 2 2 2 0 SAP domain OAD_gamma PF04277.13 OEU18594.1 - 6 7.5 6.8 24 5.6 0.4 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain AMP-binding PF00501.28 OEU18595.1 - 3.4e-40 137.9 0.0 4.6e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OEU18595.1 - 2.7e-10 40.0 2.0 8.9e-10 38.3 0.6 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OEU18595.1 - 1.3e-06 29.3 0.0 2.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 OEU18596.1 - 1.3e-67 223.7 0.3 1.4e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OEU18596.1 - 0.0095 15.1 0.3 6.8 5.8 0.0 3.1 2 1 0 3 3 3 2 Gammaproteobacterial serine protease JHD PF17811.1 OEU18596.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Jumonji helical domain Methyltransf_32 PF13679.6 OEU18597.1 - 0.00074 19.5 1.5 0.01 15.8 1.5 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU18597.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SH3_12 PF18129.1 OEU18598.1 - 0.069 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Xrn1 SH3-like domain Spc7 PF08317.11 OEU18599.1 - 0.023 13.6 0.9 0.038 12.9 0.9 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein TEX13 PF15186.6 OEU18599.1 - 0.034 13.8 0.5 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family GCP_C_terminal PF04130.13 OEU18600.1 - 4e-56 190.7 1.7 7.4e-56 189.9 1.7 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OEU18600.1 - 1.2e-53 182.8 0.0 2.1e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DEAD PF00270.29 OEU18601.1 - 1.8e-47 161.4 0.0 8.6e-47 159.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU18601.1 - 3.7e-32 111.0 0.0 1.2e-29 102.9 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OEU18601.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OEU18601.1 - 0.14 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit YL1 PF05764.13 OEU18603.1 - 1.1e-15 58.4 23.5 1.1e-15 58.4 23.5 4.2 3 2 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 OEU18603.1 - 2.4e-13 49.6 0.0 4.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BNIP2 PF12496.8 OEU18603.1 - 4.8 7.6 13.4 2.7 8.4 9.3 2.8 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SNF2_N PF00176.23 OEU18604.1 - 6.1e-59 199.5 0.0 1.6e-58 198.2 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU18604.1 - 3.6e-18 65.9 0.0 1.1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.14 OEU18604.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain RRM_1 PF00076.22 OEU18605.1 - 0.00015 21.5 0.1 0.068 13.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L6e PF01159.19 OEU18607.1 - 1.6e-36 125.2 0.1 2e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e K-box PF01486.17 OEU18608.1 - 0.063 13.5 6.2 1.2 9.3 0.1 3.0 2 0 0 2 2 2 0 K-box region Thr_synth_N PF14821.6 OEU18609.1 - 2e-27 95.2 0.0 1.1e-26 92.9 0.0 2.3 3 0 0 3 3 3 1 Threonine synthase N terminus PALP PF00291.25 OEU18609.1 - 3e-14 53.1 0.0 1.7e-13 50.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_kinase PF01513.21 OEU18610.1 - 4.5e-13 49.0 0.0 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 OEU18610.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LSM PF01423.22 OEU18611.1 - 1.3e-13 50.4 0.1 1.7e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain PAP2_C PF14360.6 OEU18612.1 - 1e-15 58.0 2.3 1e-15 58.0 2.3 3.8 4 0 0 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OEU18612.1 - 2.8e-05 23.9 8.7 0.00022 21.0 1.7 3.1 4 0 0 4 4 4 2 PAP2 superfamily PAP2_3 PF14378.6 OEU18612.1 - 0.00017 21.3 3.3 0.00017 21.3 3.3 2.4 2 0 0 2 2 2 1 PAP2 superfamily DUF5336 PF17270.2 OEU18612.1 - 0.013 15.1 0.1 0.1 12.2 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5336) ETRAMP PF09716.10 OEU18612.1 - 0.092 12.8 5.6 2.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) NADH_dehy_S2_C PF06444.11 OEU18612.1 - 2.9 8.5 11.1 4.8 7.8 3.0 4.0 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus Sigma70_ner PF04546.13 OEU18613.1 - 0.021 14.7 1.1 0.027 14.3 1.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CPT_N PF16484.5 OEU18613.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus DUF2387 PF09526.10 OEU18613.1 - 0.41 10.8 4.2 16 5.7 0.0 2.2 1 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF485 PF04341.12 OEU18614.1 - 0.0016 18.3 0.4 0.045 13.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF485 CENP-B_dimeris PF09026.10 OEU18615.1 - 0.00069 20.0 0.1 0.0012 19.2 0.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Peptidase_M3 PF01432.20 OEU18616.1 - 0.0054 16.1 1.8 0.0092 15.3 1.8 1.3 1 0 0 1 1 1 1 Peptidase family M3 PRKG1_interact PF15898.5 OEU18616.1 - 0.025 15.5 0.9 0.025 15.5 0.9 3.4 3 1 0 4 4 4 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 OEU18616.1 - 0.045 14.2 6.7 0.13 12.7 6.7 1.8 1 0 0 1 1 1 0 Cell division protein ZapB IFT20 PF14931.6 OEU18616.1 - 0.25 11.5 5.5 0.72 10.0 5.5 1.8 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 CENP-H PF05837.12 OEU18616.1 - 1.5 9.3 5.7 1 9.8 3.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 OEU18616.1 - 4.8 7.9 7.3 8.2 7.1 4.9 2.6 2 1 0 2 2 2 0 Initiation control protein YabA DUF1995 PF09353.10 OEU18617.1 - 2e-28 99.8 0.0 4.6e-28 98.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) SlyX PF04102.12 OEU18617.1 - 0.1 13.2 1.3 0.2 12.3 0.1 2.2 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.10 OEU18617.1 - 5.7 7.1 10.5 0.83 9.8 5.7 2.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myco_arth_vir_N PF09610.10 OEU18618.1 - 0.029 14.5 0.6 0.047 13.8 0.6 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) SAP PF02037.27 OEU18620.1 - 5.7e-11 41.9 2.0 5.7e-11 41.9 2.0 2.9 3 0 0 3 3 3 1 SAP domain Tho1_MOS11_C PF18592.1 OEU18620.1 - 0.00048 19.9 1.5 0.031 14.1 0.0 3.0 3 0 0 3 3 3 1 Tho1/MOS11 C-terminal domain Hamartin PF04388.12 OEU18620.1 - 1.9 7.0 4.9 2.3 6.8 4.9 1.2 1 0 0 1 1 1 0 Hamartin protein Ribosomal_L30_N PF08079.12 OEU18621.1 - 0.021 15.0 0.1 0.043 14.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain A_deaminase PF00962.22 OEU18622.1 - 5.1e-44 150.9 0.0 5.8e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 OEU18622.1 - 0.032 13.5 1.6 0.046 13.0 0.0 2.0 2 1 0 2 2 2 0 Amidohydrolase family SNAP PF14938.6 OEU18623.1 - 2.5e-89 299.5 12.5 3e-89 299.2 12.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OEU18623.1 - 2.8e-06 27.5 0.5 2.8e-06 27.5 0.5 3.4 4 1 0 4 4 4 1 Tetratricopeptide repeat NSF PF02071.20 OEU18623.1 - 0.0021 18.4 27.1 1 10.4 0.1 8.2 9 0 0 9 9 9 2 Aromatic-di-Alanine (AdAR) repeat DUF2225 PF09986.9 OEU18623.1 - 0.0057 16.4 8.7 0.093 12.4 2.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 OEU18623.1 - 0.013 16.1 8.0 1 10.2 0.0 5.7 4 2 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU18623.1 - 0.045 14.6 1.4 1.2 10.2 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF4145 PF13643.6 OEU18623.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Spatacsin_C PF14649.6 OEU18623.1 - 2 7.4 5.9 0.83 8.7 0.4 2.3 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_1 PF00515.28 OEU18623.1 - 7.7 6.5 14.4 10 6.1 0.5 5.6 3 2 1 4 4 4 0 Tetratricopeptide repeat GtrA PF04138.14 OEU18624.1 - 3.9e-07 30.3 11.1 3.9e-07 30.3 11.1 1.7 2 0 0 2 2 2 1 GtrA-like protein UCH PF00443.29 OEU18625.1 - 4e-44 151.1 0.0 4.9e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU18625.1 - 1e-14 54.8 1.3 1.2e-08 35.0 0.4 2.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Enolase_N PF03952.16 OEU18625.1 - 0.21 11.7 0.7 0.46 10.7 0.7 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain OAD_gamma PF04277.13 OEU18625.1 - 0.59 10.8 3.0 1.7 9.3 3.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain UIM PF02809.20 OEU18625.1 - 3.8 7.6 9.2 0.44 10.6 3.0 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Arginase PF00491.21 OEU18626.1 - 2.4e-66 224.1 0.0 3e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF3672 PF12421.8 OEU18626.1 - 0.043 13.7 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III protein Iso_dh PF00180.20 OEU18629.1 - 2.6e-23 82.7 0.0 4.2e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_1 PF00036.32 OEU18629.1 - 1.7e-07 30.3 0.6 4.1e-07 29.1 0.6 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OEU18629.1 - 2.3e-05 23.9 0.2 7.5e-05 22.4 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OEU18629.1 - 3.1e-05 24.3 0.0 7.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU18629.1 - 0.00028 20.2 0.3 0.00061 19.2 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OEU18629.1 - 0.00079 19.2 0.6 0.002 17.9 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair DIOX_N PF14226.6 OEU18630.1 - 2.6e-25 89.5 0.0 4.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OEU18630.1 - 3.9e-19 69.0 0.1 6.9e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_4 PF12799.7 OEU18631.1 - 0.052 14.0 0.0 0.23 11.9 0.0 2.2 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) UAA PF08449.11 OEU18632.1 - 4.1e-38 131.3 9.4 6.3e-38 130.7 9.4 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU18632.1 - 1.1e-07 32.1 22.5 4.8e-06 26.8 11.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 OEU18632.1 - 0.0066 15.4 0.5 0.0066 15.4 0.5 2.5 1 1 1 3 3 3 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 OEU18632.1 - 0.064 12.6 9.4 0.23 10.8 0.6 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family Xpo1 PF08389.12 OEU18633.1 - 8.5e-12 45.4 0.9 8.5e-12 45.4 0.9 4.1 6 0 0 6 6 6 1 Exportin 1-like protein CRM1_repeat PF18777.1 OEU18633.1 - 0.023 14.2 0.8 0.065 12.8 0.8 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat REV PF00424.18 OEU18633.1 - 4.4 7.4 7.0 2 8.5 0.0 3.1 2 1 0 3 3 3 0 REV protein (anti-repression trans-activator protein) FYVE PF01363.21 OEU18634.1 - 1.4e-11 44.4 9.5 1.4e-11 44.4 9.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger FYVE PF01363.21 OEU18635.1 - 8.7e-14 51.4 5.7 9.6e-14 51.3 5.7 1.0 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 OEU18635.1 - 0.035 14.3 10.3 0.035 14.3 10.3 2.2 2 1 0 2 2 2 0 AN1-like Zinc finger DUF2180 PF09947.9 OEU18635.1 - 0.076 13.0 3.2 0.05 13.6 1.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) DZR PF12773.7 OEU18635.1 - 0.15 12.1 9.1 1.2 9.2 9.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 OEU18635.1 - 0.19 12.0 7.7 1.5 9.1 7.7 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Rad50_zn_hook PF04423.14 OEU18635.1 - 0.43 10.5 2.9 1.9 8.4 0.2 2.1 1 1 1 2 2 2 0 Rad50 zinc hook motif XPA_N PF01286.18 OEU18635.1 - 0.66 10.1 13.4 5.1 7.2 0.1 3.1 2 1 1 3 3 3 0 XPA protein N-terminal PPR_long PF17177.4 OEU18636.1 - 0.02 14.2 0.0 0.07 12.5 0.0 1.9 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP AAA PF00004.29 OEU18637.1 - 9.6e-13 48.7 0.0 1.7e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 OEU18637.1 - 1.3e-12 47.7 0.1 2.8e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 OEU18637.1 - 0.0004 19.8 0.3 0.0036 16.7 0.2 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 OEU18637.1 - 0.0005 20.0 0.3 0.0021 18.0 0.3 2.0 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 OEU18637.1 - 0.00074 20.1 0.3 0.021 15.4 0.1 2.9 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OEU18637.1 - 0.00082 19.7 0.6 0.34 11.2 0.3 2.5 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OEU18637.1 - 0.0015 18.9 0.8 0.0079 16.5 0.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OEU18637.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 OEU18637.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OEU18637.1 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 OEU18637.1 - 0.0088 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OEU18637.1 - 0.011 14.9 1.3 0.26 10.5 1.3 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 OEU18637.1 - 0.014 15.1 0.1 0.92 9.1 0.1 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 OEU18637.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OEU18637.1 - 0.018 15.1 0.2 0.055 13.5 0.2 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 OEU18637.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ Nsp1_C PF05064.13 OEU18637.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region RNA_helicase PF00910.22 OEU18637.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OEU18637.1 - 0.026 14.8 1.6 0.036 14.3 0.5 1.8 2 1 0 2 2 1 0 AAA domain RuvB_N PF05496.12 OEU18637.1 - 0.034 13.9 0.3 0.26 11.0 0.3 2.5 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TrwB_AAD_bind PF10412.9 OEU18637.1 - 0.035 13.0 0.1 0.067 12.1 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain APS_kinase PF01583.20 OEU18637.1 - 0.036 13.9 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 OEU18637.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 OEU18637.1 - 0.045 13.3 0.2 0.26 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU18637.1 - 0.052 13.9 0.2 0.12 12.7 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 OEU18637.1 - 0.063 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OEU18637.1 - 0.063 12.2 0.5 0.14 11.1 0.4 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ComJ PF11033.8 OEU18637.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Competence protein J (ComJ) PhoH PF02562.16 OEU18637.1 - 0.089 12.2 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 OEU18637.1 - 0.096 12.4 0.4 0.38 10.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OEU18637.1 - 0.11 12.2 0.8 0.95 9.1 0.3 2.3 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OEU18637.1 - 0.16 11.1 0.2 2.4 7.2 0.0 2.4 2 1 1 3 3 2 0 NB-ARC domain UCH PF00443.29 OEU18638.1 - 9.5e-40 136.7 0.0 2.1e-29 102.8 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU18638.1 - 1.1e-21 77.8 0.3 4.3e-16 59.4 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SecIII_SopE_N PF05364.14 OEU18638.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus zf-Sec23_Sec24 PF04810.15 OEU18638.1 - 0.15 12.1 2.7 4.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rubredoxin_2 PF18073.1 OEU18638.1 - 2.1 8.2 6.4 15 5.4 0.6 2.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain Peptidase_C2 PF00648.21 OEU18639.1 - 1.6e-38 132.4 0.0 3.1e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 OEU18639.1 - 8e-06 25.8 5.3 0.0062 16.6 1.3 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 OEU18639.1 - 3.5e-05 24.1 0.0 0.015 15.6 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III SAM_decarbox PF01536.16 OEU18640.1 - 3.1e-87 292.9 0.0 7.2e-87 291.7 0.0 1.5 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase AdoMet_dc PF02675.15 OEU18640.1 - 0.0015 18.8 0.0 0.0055 16.9 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine decarboxylase Rad51 PF08423.11 OEU18641.1 - 3.7e-07 29.7 0.1 0.026 13.8 0.0 2.4 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 OEU18641.1 - 0.00012 21.8 0.0 0.00032 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OEU18641.1 - 0.00023 20.5 0.4 0.00023 20.5 0.4 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OEU18641.1 - 0.0096 15.7 0.4 0.11 12.3 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU18641.1 - 0.024 14.9 0.6 0.1 12.9 0.4 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OEU18641.1 - 0.063 13.0 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 OEU18641.1 - 0.091 12.9 0.5 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU18641.1 - 0.14 12.0 0.8 23 4.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OEU18641.1 - 0.2 12.1 0.6 0.82 10.1 0.6 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OEU18641.1 - 0.84 10.2 5.4 0.32 11.5 0.2 3.0 2 1 1 3 3 3 0 AAA domain EphA2_TM PF14575.6 OEU18641.1 - 1.8 9.5 4.4 1.3e+02 3.6 0.1 3.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 OEU18641.1 - 6.1 7.5 8.4 29 5.4 0.3 3.4 4 0 0 4 4 4 0 WW domain-binding protein 1 Ribonuc_red_lgC PF02867.15 OEU18642.1 - 2.7e-183 610.3 0.0 3.2e-183 610.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OEU18642.1 - 3.3e-22 78.3 0.0 6.7e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OEU18642.1 - 1e-16 61.3 0.0 3.3e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain AreA_N PF07573.11 OEU18642.1 - 0.33 11.6 0.9 1.3 9.7 0.0 2.4 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus RRM_1 PF00076.22 OEU18643.1 - 6.4e-16 57.9 0.0 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 OEU18643.1 - 1.8e-07 31.0 0.1 5.1e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 Surp module RRM_7 PF16367.5 OEU18643.1 - 0.00016 21.7 0.0 0.00037 20.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OEU18643.1 - 0.034 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif YolD PF08863.10 OEU18643.1 - 0.39 10.8 2.8 0.79 9.8 0.1 2.3 2 0 0 2 2 2 0 YolD-like protein DUF4505 PF14956.6 OEU18644.1 - 3.8e-27 95.2 2.3 8.9e-27 94.0 2.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4505) SUB1_ProdP9 PF18213.1 OEU18644.1 - 0.067 13.0 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Me-amine-dh_L PF02975.14 OEU18645.1 - 0.022 15.3 2.0 0.096 13.2 2.1 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase, L chain Ribosomal_S7e PF01251.18 OEU18646.1 - 6.2e-77 257.5 0.7 7.1e-77 257.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TNFR_16_TM PF18422.1 OEU18646.1 - 0.16 12.0 0.2 0.26 11.3 0.2 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Tic22 PF04278.12 OEU18648.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Tic22-like family DUF4357 PF14267.6 OEU18648.1 - 0.16 11.9 0.7 0.46 10.5 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) EMP24_GP25L PF01105.24 OEU18649.1 - 7.6e-19 68.3 3.1 1.9e-18 67.1 3.1 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF223 PF02721.14 OEU18649.1 - 0.014 15.7 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 T-box PF00907.22 OEU18649.1 - 0.051 13.8 1.1 0.075 13.3 1.1 1.4 1 1 0 1 1 1 0 T-box Adaptin_binding PF10199.9 OEU18649.1 - 5.2 7.7 10.5 8.9 6.9 10.3 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 rve PF00665.26 OEU18650.1 - 0.051 13.8 0.0 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 Integrase core domain MnmE_helical PF12631.7 OEU18651.1 - 0.012 15.8 1.1 0.023 14.9 1.1 1.4 1 0 0 1 1 1 0 MnmE helical domain Retrotran_gag_2 PF14223.6 OEU18651.1 - 0.045 13.4 6.5 0.11 12.1 0.1 2.6 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type JAB PF01398.21 OEU18653.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease P-mevalo_kinase PF04275.14 OEU18653.1 - 0.026 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphomevalonate kinase tRNA-synt_2 PF00152.20 OEU18654.1 - 2.6e-74 250.1 0.1 3.2e-74 249.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OEU18654.1 - 3.7e-15 55.7 0.0 9e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OEU18654.1 - 2.6e-06 27.1 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3799 PF12684.7 OEU18654.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) GST_C_2 PF13410.6 OEU18654.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YbaB_DNA_bd PF02575.16 OEU18655.1 - 6.1e-07 29.6 1.2 4.3e-06 26.9 1.2 2.0 1 1 0 1 1 1 1 YbaB/EbfC DNA-binding family TQ PF18202.1 OEU18655.1 - 0.11 13.0 1.7 8.8 6.9 0.1 2.1 1 1 1 2 2 2 0 T-Q ester bond containing domain MIF4G PF02854.19 OEU18656.1 - 1.9e-21 76.7 1.2 4e-21 75.6 1.2 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OEU18656.1 - 3.9e-13 49.4 0.4 1.1e-12 47.9 0.1 2.0 2 0 0 2 2 2 1 MA3 domain tRNA_m1G_MT PF01746.21 OEU18657.1 - 7.7e-28 97.5 0.1 1.1e-27 97.0 0.1 1.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Kelch_1 PF01344.25 OEU18657.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Gpi1 PF05024.15 OEU18658.1 - 2.6e-36 125.4 9.9 5e-36 124.5 9.9 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3300 PF11737.8 OEU18658.1 - 0.18 11.3 1.3 0.32 10.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Rep_fac_C PF08542.11 OEU18659.1 - 4.2e-24 84.8 0.0 2e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 OEU18659.1 - 4.8e-15 56.2 0.0 8.4e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OEU18659.1 - 3.2e-09 36.8 0.2 8.7e-08 32.1 0.5 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 OEU18659.1 - 6.6e-07 29.7 0.1 0.00086 19.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 OEU18659.1 - 1.4e-06 28.4 0.0 3.2e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 OEU18659.1 - 4.3e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU18659.1 - 1.9e-05 25.1 0.1 0.0035 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 OEU18659.1 - 6.1e-05 22.5 0.0 0.0014 18.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 OEU18659.1 - 0.00012 22.4 0.0 0.00035 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 OEU18659.1 - 0.0002 21.4 0.0 0.0005 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OEU18659.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU18659.1 - 0.00074 19.3 0.0 0.0024 17.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 OEU18659.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OEU18659.1 - 0.0023 17.7 0.0 0.0068 16.2 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OEU18659.1 - 0.0023 18.4 0.0 0.0062 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OEU18659.1 - 0.0028 18.0 0.0 0.008 16.6 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 OEU18659.1 - 0.0038 17.0 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU18659.1 - 0.004 17.3 0.2 0.008 16.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain DUF4470 PF14737.6 OEU18659.1 - 0.0055 16.9 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) NTPase_1 PF03266.15 OEU18659.1 - 0.0066 16.4 0.1 0.12 12.3 0.0 2.3 1 1 0 2 2 2 1 NTPase MeaB PF03308.16 OEU18659.1 - 0.0076 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 OEU18659.1 - 0.0081 16.5 0.3 0.034 14.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OEU18659.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OEU18659.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 OEU18659.1 - 0.02 14.3 0.1 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OEU18659.1 - 0.022 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 OEU18659.1 - 0.024 14.9 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OEU18659.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DNA_pol3_delta PF06144.13 OEU18659.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_25 PF13481.6 OEU18659.1 - 0.042 13.4 0.1 0.088 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF5119 PF17145.4 OEU18659.1 - 0.047 13.7 0.0 1.1 9.2 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5119) DEAD PF00270.29 OEU18659.1 - 0.051 13.3 0.2 2.3 8.0 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase HEAT_2 PF13646.6 OEU18659.1 - 0.054 13.9 0.0 0.4 11.1 0.0 2.4 3 0 0 3 3 1 0 HEAT repeats MCM PF00493.23 OEU18659.1 - 0.056 12.5 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain PhoH PF02562.16 OEU18659.1 - 0.06 12.8 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.13 OEU18659.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KTI12 PF08433.10 OEU18659.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 OEU18659.1 - 0.091 12.7 0.0 0.68 9.8 0.0 2.1 1 1 0 2 2 2 0 NACHT domain Cyclin_N PF00134.23 OEU18660.1 - 1.9e-16 59.9 0.0 3.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU18660.1 - 1.1e-05 25.4 0.4 0.00017 21.6 0.2 2.7 2 1 1 3 3 3 1 Cyclin, C-terminal domain Sigma_1s PF02454.16 OEU18660.1 - 0.0061 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Sigma 1s protein UPF0565 PF10561.9 OEU18660.1 - 0.015 14.5 0.4 0.023 13.9 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Cyclin_C_2 PF16899.5 OEU18660.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Cyclin C-terminal domain Methyltransf_21 PF05050.12 OEU18661.1 - 2.1e-11 44.1 1.2 3.2e-10 40.3 0.4 2.0 1 1 1 2 2 2 2 Methyltransferase FkbM domain TMEM51 PF15345.6 OEU18662.1 - 0.0034 17.3 0.1 0.0097 15.8 0.1 1.8 1 0 0 1 1 1 1 Transmembrane protein 51 PT PF04886.12 OEU18662.1 - 0.051 13.1 64.7 0.18 11.3 19.1 4.6 3 1 1 4 4 4 0 PT repeat SID-1_RNA_chan PF13965.6 OEU18664.1 - 0.21 10.0 2.1 0.22 9.9 2.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Fib_alpha PF08702.10 OEU18664.1 - 0.46 10.7 9.6 0.67 10.1 8.6 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Dicty_REP PF05086.12 OEU18664.1 - 9.8 4.0 17.1 12 3.7 17.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein VASt PF16016.5 OEU18665.1 - 3.7e-10 40.4 0.0 5.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Peptidase_A22B PF04258.13 OEU18666.1 - 2.5e-81 273.3 2.5 3.3e-81 272.9 2.5 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OEU18666.1 - 2.6e-05 23.9 1.0 2.6e-05 23.9 1.0 1.8 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 OEU18666.1 - 0.0093 14.8 0.7 0.0093 14.8 0.7 1.9 2 0 0 2 2 2 1 Presenilin Myb_DNA-bind_6 PF13921.6 OEU18667.1 - 3.6e-21 75.2 9.2 8.6e-13 48.3 2.1 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OEU18667.1 - 3.8e-21 75.0 16.5 5e-10 39.4 0.2 3.8 3 2 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OEU18667.1 - 5.3e-05 23.4 5.4 0.086 13.2 0.9 3.3 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 OEU18667.1 - 0.00099 19.3 1.7 0.03 14.5 0.1 2.8 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OEU18667.1 - 0.004 17.5 12.3 0.26 11.7 0.7 4.3 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain DUF5591 PF17884.1 OEU18667.1 - 0.0065 16.3 1.9 6.6 6.6 0.1 3.0 1 1 1 3 3 3 2 Domain of unknown function (DUF5591) IRF PF00605.17 OEU18667.1 - 0.54 10.6 5.4 0.73 10.2 0.1 3.2 1 1 1 3 3 3 0 Interferon regulatory factor transcription factor CAF1A PF12253.8 OEU18668.1 - 3.8e-23 81.4 7.3 3.8e-23 81.4 7.3 4.7 4 2 0 4 4 4 1 Chromatin assembly factor 1 subunit A Ion_trans_2 PF07885.16 OEU18669.1 - 1.1e-12 47.7 0.8 1.8e-12 47.0 0.8 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 OEU18669.1 - 2.8e-09 36.6 2.7 3.6e-09 36.2 2.7 1.1 1 0 0 1 1 1 1 Ion transport protein zf-ribbon_3 PF13248.6 OEU18669.1 - 0.0076 15.6 1.9 0.0084 15.5 0.5 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Cript PF10235.9 OEU18669.1 - 0.081 13.5 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DZR PF12773.7 OEU18669.1 - 0.092 12.8 1.5 0.2 11.7 1.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 OEU18669.1 - 0.15 12.1 0.9 0.33 11.0 0.9 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF3245 PF11595.8 OEU18670.1 - 0.034 14.6 0.7 0.034 14.6 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.6 OEU18670.1 - 0.39 11.1 3.5 0.68 10.3 3.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPT PF03151.16 OEU18671.1 - 1.7e-17 63.7 19.9 1.9e-17 63.5 19.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU18671.1 - 2.5e-10 40.7 32.5 1.9e-05 24.8 12.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OEU18671.1 - 0.00039 19.7 19.8 0.00052 19.3 19.8 1.2 1 0 0 1 1 1 1 UAA transporter family Phage_holin_2_1 PF04971.12 OEU18671.1 - 5.7 7.0 6.8 14 5.8 0.2 3.2 2 1 0 3 3 3 0 Bacteriophage P21 holin S SCO1-SenC PF02630.14 OEU18672.1 - 8.1e-43 145.6 0.0 1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 OEU18672.1 - 3.9e-06 27.1 0.0 1.3e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU18672.1 - 0.021 14.7 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family Arc_PepC_II PF06847.11 OEU18672.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Caskin-Pro-rich PF16907.5 OEU18672.1 - 2.8 8.5 5.2 5.6 7.6 5.2 1.5 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Glyco_transf_92 PF01697.27 OEU18673.1 - 1.3e-16 61.1 0.1 2.6e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU18673.1 - 8.5e-07 29.4 0.1 3.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 WW PF00397.26 OEU18674.1 - 1.5e-17 63.3 4.4 5.1e-09 36.1 0.6 2.4 2 0 0 2 2 2 2 WW domain NST1 PF13945.6 OEU18674.1 - 0.016 15.3 15.0 0.026 14.6 15.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator BRF1 PF07741.13 OEU18674.1 - 0.021 15.2 7.9 0.047 14.0 7.9 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2126 PF09899.9 OEU18674.1 - 0.029 12.5 0.6 0.035 12.2 0.6 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Glyco_hyd_101C PF17451.2 OEU18674.1 - 0.03 14.6 9.7 0.21 11.8 5.2 2.7 2 1 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Orf78 PF06024.12 OEU18674.1 - 0.14 12.5 6.4 0.25 11.7 6.4 1.5 1 0 0 1 1 1 0 Orf78 (ac78) CDC45 PF02724.14 OEU18674.1 - 0.39 9.0 4.3 0.42 8.8 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1980 PF09323.10 OEU18674.1 - 1.1 9.1 5.4 1.8 8.4 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Macoilin PF09726.9 OEU18674.1 - 1.7 7.1 7.9 1.8 7.0 7.9 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OEU18674.1 - 2.4 6.8 5.0 2.3 6.9 5.0 1.1 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 OEU18677.1 - 3.3e-09 37.2 14.5 1.2e-05 25.9 0.0 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU18677.1 - 0.002 18.4 0.0 0.03 14.6 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OEU18677.1 - 0.0032 16.6 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Pkinase PF00069.25 OEU18679.1 - 6e-54 183.2 0.0 9.6e-53 179.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU18679.1 - 2e-53 181.3 0.0 2.4e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OEU18679.1 - 2e-05 25.1 0.0 0.00018 22.0 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 OEU18679.1 - 4e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OEU18679.1 - 0.00017 21.8 0.1 0.00054 20.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU18679.1 - 0.00062 20.0 0.0 0.0036 17.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat APH PF01636.23 OEU18679.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YukC PF10140.9 OEU18679.1 - 0.033 13.0 0.2 0.47 9.2 0.0 2.0 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Pkinase_fungal PF17667.1 OEU18679.1 - 0.035 12.9 0.1 0.087 11.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OEU18679.1 - 0.039 13.0 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_2 PF12796.7 OEU18680.1 - 8.9e-14 51.8 0.0 4.5e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU18680.1 - 5.7e-12 45.9 0.1 2.9e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU18680.1 - 2.2e-09 37.4 0.0 5.2e-07 29.8 0.0 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU18680.1 - 2.4e-08 33.6 0.0 4.7e-05 23.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU18680.1 - 2.6e-08 33.9 0.0 8.7e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Popeye PF04831.13 OEU18683.1 - 3.6e-09 36.9 0.0 4.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 OEU18683.1 - 5.2e-07 29.7 0.1 0.0055 16.7 0.0 2.8 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain C_LFY_FLO PF17538.2 OEU18684.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula 5_nucleotid PF05761.14 OEU18685.1 - 4.3e-132 441.3 4.0 5.2e-132 441.0 4.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family Methyltransf_16 PF10294.9 OEU18686.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase K-box PF01486.17 OEU18687.1 - 0.081 13.1 0.8 0.16 12.2 0.8 1.5 1 1 0 1 1 1 0 K-box region TAP35_44 PF07265.11 OEU18687.1 - 0.13 12.3 0.5 0.24 11.4 0.5 1.4 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 QueH PF02677.14 OEU18688.1 - 0.074 13.2 0.1 0.09 12.9 0.1 1.1 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH DUF1120 PF06551.12 OEU18690.1 - 0.32 11.2 0.0 0.32 11.2 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1120) DUF481 PF04338.12 OEU18690.1 - 0.62 10.0 2.9 0.77 9.7 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF481 DUF2207 PF09972.9 OEU18691.1 - 0.29 9.9 2.4 0.41 9.4 2.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 OEU18691.1 - 2.1 8.4 12.6 2.6 8.2 0.8 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase FUN14 PF04930.15 OEU18692.1 - 0.044 14.2 1.1 0.088 13.2 1.1 1.5 1 0 0 1 1 1 0 FUN14 family DUF4486 PF14858.6 OEU18692.1 - 0.076 11.5 0.3 2.3 6.6 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4486) RNB PF00773.19 OEU18693.1 - 2.6e-97 326.1 0.1 6.3e-97 324.8 0.0 1.7 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 OEU18693.1 - 1.1e-17 63.8 0.0 2.4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 OEU18693.1 - 3.4e-08 33.8 1.7 3.4e-08 33.8 1.7 2.0 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 OEU18693.1 - 1.3e-06 28.5 0.0 4.2e-05 23.6 0.0 3.1 2 1 1 3 3 3 1 Cold shock domain Rrp44_S1 PF17215.3 OEU18693.1 - 0.00013 21.8 0.1 0.00054 19.9 0.1 2.1 1 1 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 OEU18693.1 - 0.19 11.4 1.1 3 7.6 0.0 3.1 2 1 0 2 2 2 0 Rrp44-like cold shock domain PUF PF00806.19 OEU18694.1 - 0.00013 21.4 0.0 22 5.0 0.0 5.2 5 0 0 5 5 5 0 Pumilio-family RNA binding repeat EarP PF10093.9 OEU18694.1 - 0.00031 19.9 11.2 0.035 13.2 1.0 3.5 1 1 3 4 4 4 3 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Amelotin PF15757.5 OEU18694.1 - 0.00046 19.8 6.1 0.18 11.4 0.1 3.8 1 1 2 3 3 3 2 Amelotin Motilin_assoc PF04643.12 OEU18694.1 - 0.0038 17.1 6.9 27 4.7 0.0 5.0 5 0 0 5 5 5 0 Motilin/ghrelin-associated peptide Arteri_nsp7a PF16749.5 OEU18694.1 - 0.0056 16.9 3.2 2.3 8.4 0.6 3.6 1 1 2 3 3 3 1 Arterivirus nonstructural protein 7 alpha RNA_GG_bind PF10258.9 OEU18694.1 - 0.029 14.4 9.6 9.9 6.3 0.0 5.7 5 1 1 6 6 6 0 PHAX RNA-binding domain Josephin PF02099.17 OEU18694.1 - 0.1 12.7 0.1 0.1 12.7 0.1 4.9 3 2 1 4 4 4 0 Josephin VWA_3 PF13768.6 OEU18694.1 - 0.88 9.5 5.9 0.61 10.0 2.1 2.5 1 1 0 2 2 2 0 von Willebrand factor type A domain Guanylin PF02058.15 OEU18694.1 - 8.3 7.0 10.1 48 4.5 0.2 4.7 3 1 1 5 5 5 0 Guanylin precursor DDT PF02791.17 OEU18696.1 - 0.087 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 DDT domain MutS_V PF00488.21 OEU18697.1 - 1.8e-18 67.3 0.0 2.2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 MutS domain V AAA_22 PF13401.6 OEU18697.1 - 0.031 14.5 0.3 0.093 13.0 0.3 1.9 1 1 0 1 1 1 0 AAA domain Beta_helix_2 PF18835.1 OEU18697.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase AAA_24 PF13479.6 OEU18697.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OEU18697.1 - 0.25 10.2 1.3 5.2 5.9 1.5 1.9 1 1 1 2 2 2 0 AAA-like domain DUF4986 PF16375.5 OEU18698.1 - 0.0053 17.4 0.7 0.02 15.6 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function HA PF03457.14 OEU18699.1 - 4.2e-40 135.9 10.7 3.9e-19 68.7 0.3 3.0 3 0 0 3 3 3 3 Helicase associated domain Ribosomal_L13e PF01294.18 OEU18699.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L13e DUF4238 PF14022.6 OEU18699.1 - 0.2 11.1 4.0 0.67 9.4 1.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4238) CDC45 PF02724.14 OEU18700.1 - 0.02 13.2 15.4 0.026 12.9 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 OEU18700.1 - 0.021 14.6 4.3 0.025 14.3 4.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2722 PF10846.8 OEU18700.1 - 0.15 10.9 7.4 0.16 10.9 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Cwf_Cwc_15 PF04889.12 OEU18700.1 - 0.17 11.6 16.2 0.24 11.1 16.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 OEU18700.1 - 0.43 11.1 9.2 0.73 10.3 9.2 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.12 OEU18700.1 - 0.92 8.8 21.0 1.2 8.3 21.0 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OEU18700.1 - 1 8.8 13.9 0.91 8.9 13.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OEU18700.1 - 1.1 7.4 14.1 1.2 7.3 14.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OEU18700.1 - 1.4 7.0 21.6 1.7 6.6 21.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 OEU18700.1 - 1.4 7.9 21.4 1.8 7.6 21.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 OEU18700.1 - 1.8 8.1 8.4 2.2 7.8 8.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NPR3 PF03666.13 OEU18700.1 - 2.8 6.6 5.7 3.6 6.3 5.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 OEU18700.1 - 4.9 7.0 17.1 5 7.0 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 OEU18700.1 - 7.4 6.5 18.8 9.5 6.2 18.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Methyltransf_15 PF09445.10 OEU18701.1 - 2.3e-18 66.3 0.0 4.9e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 OEU18701.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa 3HCDH_N PF02737.18 OEU18702.1 - 5.8e-52 176.2 0.8 9.1e-52 175.5 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 OEU18702.1 - 8.6e-43 146.5 0.0 1.6e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 OEU18702.1 - 2.8e-30 104.8 0.0 3.1e-22 79.0 0.0 3.2 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 OEU18702.1 - 1.1e-20 74.5 0.0 1.8e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 2-Hacid_dh_C PF02826.19 OEU18702.1 - 0.012 15.0 0.2 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OEU18702.1 - 0.028 13.7 0.0 0.069 12.4 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Flu_B_M2 PF04772.12 OEU18702.1 - 0.031 14.5 1.9 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Influenza B matrix protein 2 (BM2) NAD_binding_2 PF03446.15 OEU18702.1 - 0.036 14.3 2.2 0.067 13.4 0.3 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 OEU18702.1 - 0.038 14.5 0.4 0.29 11.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OEU18702.1 - 0.05 13.2 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OEU18702.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus dCache_2 PF08269.11 OEU18702.1 - 0.32 10.1 2.4 1.6 7.8 0.1 2.4 2 1 0 2 2 2 0 Cache domain DUF3290 PF11694.8 OEU18703.1 - 3.9 7.4 5.9 2 8.4 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Muted PF14942.6 OEU18705.1 - 0.0026 18.1 2.5 0.0026 18.1 2.5 1.7 1 1 1 2 2 2 1 Organelle biogenesis, Muted-like protein RRP36 PF06102.12 OEU18705.1 - 0.013 15.4 2.8 0.02 14.9 2.8 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF948 PF06103.11 OEU18705.1 - 5.7 7.3 9.3 2.9 8.2 0.6 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2564 PF10819.8 OEU18705.1 - 7.6 7.0 8.7 1.9e+02 2.5 8.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) SART-1 PF03343.13 OEU18706.1 - 9.9e-18 64.0 5.7 5.2e-17 61.7 5.7 1.9 1 1 0 1 1 1 1 SART-1 family AIRS_C PF02769.22 OEU18706.1 - 0.042 14.0 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain DAO PF01266.24 OEU18707.1 - 6.1e-55 187.2 0.0 6.9e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU18707.1 - 3.8e-06 26.4 0.6 2.9e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OEU18707.1 - 7.8e-05 22.6 0.1 0.00012 22.1 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 OEU18707.1 - 0.00011 22.3 0.4 0.00032 20.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OEU18707.1 - 0.00052 19.4 0.3 0.00077 18.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OEU18707.1 - 0.00075 20.0 0.6 0.0015 19.0 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OEU18707.1 - 0.0013 19.0 0.1 0.0021 18.3 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OEU18707.1 - 0.0041 16.5 0.1 0.0059 15.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OEU18707.1 - 0.0043 16.2 1.3 0.0067 15.5 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OEU18707.1 - 0.0061 15.8 0.4 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Sacchrp_dh_NADP PF03435.18 OEU18707.1 - 0.0069 16.6 0.1 0.47 10.7 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OEU18707.1 - 0.0075 15.9 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 OEU18707.1 - 0.014 15.0 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 OEU18707.1 - 0.019 13.7 0.9 0.053 12.2 1.1 1.6 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.25 OEU18707.1 - 0.043 13.3 0.6 0.99 8.8 0.4 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Pyr_redox_3 PF13738.6 OEU18707.1 - 0.053 12.8 1.8 0.08 12.2 1.8 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 OEU18707.1 - 0.078 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 OEU18707.1 - 0.082 12.0 0.8 0.18 10.9 0.8 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A F420_oxidored PF03807.17 OEU18707.1 - 0.083 13.5 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OEU18707.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 OEU18707.1 - 0.16 12.4 0.7 0.43 11.0 0.6 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 OEU18707.1 - 0.17 11.5 0.1 7.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Lycopene_cycl PF05834.12 OEU18707.1 - 0.26 10.3 0.3 2.4 7.1 0.6 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Beta_elim_lyase PF01212.21 OEU18708.1 - 7.5e-73 245.4 0.1 8.7e-73 245.1 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OEU18708.1 - 2.4e-08 33.5 0.0 3.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OEU18708.1 - 0.0017 17.8 0.6 0.0068 15.8 0.0 2.0 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OEU18708.1 - 0.024 13.6 0.0 0.046 12.7 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V Pyridoxal_deC PF00282.19 OEU18708.1 - 0.031 13.0 0.1 0.17 10.5 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain PROCN PF08083.11 OEU18710.1 - 4.7e-231 766.6 7.3 6.9e-231 766.1 7.3 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OEU18710.1 - 1.6e-128 427.1 0.3 2.7e-128 426.4 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OEU18710.1 - 1.1e-87 292.0 2.5 2.7e-87 290.7 2.5 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 OEU18710.1 - 2.9e-71 237.8 0.0 6.1e-71 236.8 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.11 OEU18710.1 - 1.4e-65 219.9 0.3 4.3e-65 218.3 0.3 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 OEU18710.1 - 2.3e-46 156.0 0.5 7e-46 154.5 0.5 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OEU18710.1 - 1.9e-43 147.3 0.1 5.4e-43 145.8 0.1 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 OEU18710.1 - 0.00054 19.9 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PAP_fibrillin PF04755.12 OEU18711.1 - 2.6e-11 43.9 0.3 5.2e-10 39.6 0.2 2.0 2 0 0 2 2 2 2 PAP_fibrillin GTP-bdg_N PF13167.6 OEU18712.1 - 8.8e-29 100.0 0.5 2.3e-28 98.7 0.5 1.8 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 OEU18712.1 - 1.8e-28 99.0 4.2 3.1e-28 98.2 4.2 1.4 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 OEU18712.1 - 7.2e-21 74.4 0.2 3.5e-20 72.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU18712.1 - 2.3e-05 24.0 0.3 8.4e-05 22.2 0.1 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 OEU18712.1 - 0.00018 21.2 2.5 0.0015 18.2 0.1 2.7 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 OEU18712.1 - 0.0002 21.0 0.6 0.0032 17.0 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OEU18712.1 - 0.00023 21.3 0.1 0.002 18.2 0.1 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 OEU18712.1 - 0.0003 20.7 0.3 0.59 10.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 OEU18712.1 - 0.0039 17.2 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 OEU18712.1 - 0.0049 16.7 1.1 0.05 13.4 0.1 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OEU18712.1 - 0.019 14.3 0.0 0.053 12.9 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OEU18712.1 - 0.076 13.4 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sec1 PF00995.23 OEU18713.1 - 7.1e-105 352.4 0.1 7.1e-105 352.4 0.1 1.4 2 0 0 2 2 2 1 Sec1 family Ribosomal_L17 PF01196.19 OEU18714.1 - 4e-32 111.0 0.2 5.7e-32 110.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 R-HINP1I PF11463.8 OEU18715.1 - 0.0093 15.4 0.3 0.0099 15.3 0.3 1.0 1 0 0 1 1 1 1 R.HinP1I restriction endonuclease PEPcase_2 PF14010.6 OEU18715.1 - 0.077 11.5 0.1 0.082 11.4 0.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Glyco_tran_28_C PF04101.16 OEU18716.1 - 1.8e-20 73.6 0.0 2.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Kelch_4 PF13418.6 OEU18717.1 - 4.2e-38 129.1 17.8 1.6e-10 40.8 0.3 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OEU18717.1 - 4.5e-35 118.8 23.6 5.9e-09 35.9 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OEU18717.1 - 8.8e-35 118.3 13.8 4.4e-07 30.0 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OEU18717.1 - 3.4e-34 116.2 20.2 3.1e-11 42.7 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OEU18717.1 - 1.6e-31 107.1 26.9 1.2e-08 34.6 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 OEU18717.1 - 3.1e-29 100.4 22.2 1.2e-08 34.7 0.3 6.3 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 OEU18717.1 - 3.2e-22 78.8 0.1 6.2e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain RIBIOP_C PF04950.12 OEU18718.1 - 2e-77 260.5 0.0 2.4e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal EF_TS PF00889.19 OEU18720.1 - 7.4e-47 159.7 0.2 8.9e-47 159.4 0.2 1.1 1 0 0 1 1 1 1 Elongation factor TS MRP-L28 PF09812.9 OEU18721.1 - 4.6e-08 33.4 4.3 6.9e-08 32.8 4.3 1.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 z-alpha PF02295.17 OEU18721.1 - 0.018 15.1 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain SR-25 PF10500.9 OEU18721.1 - 9.2 5.8 21.3 17 4.9 21.2 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 OEU18723.1 - 0.044 13.8 18.7 0.066 13.2 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3835 PF12927.7 OEU18723.1 - 0.057 14.3 3.3 0.14 13.1 1.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3835) Spt20 PF12090.8 OEU18723.1 - 0.61 9.7 22.3 0.25 10.9 3.9 2.4 2 0 0 2 2 2 0 Spt20 family RVT_1 PF00078.27 OEU18724.1 - 5.7e-07 29.3 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU18724.1 - 0.0038 17.9 0.6 0.025 15.3 0.6 2.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_C48 PF02902.19 OEU18725.1 - 5.9e-22 78.6 2.1 5.9e-22 78.6 2.1 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain AGO_N PF18236.1 OEU18725.1 - 0.31 11.3 4.0 0.22 11.7 0.8 2.5 2 0 0 2 2 2 0 Argonaute N domain THDPS_M PF14789.6 OEU18729.1 - 0.087 12.9 0.1 0.35 11.0 0.1 2.0 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle Linker_histone PF00538.19 OEU18733.1 - 1.1e-12 48.1 2.2 1.1e-12 48.1 2.2 2.5 2 1 0 2 2 2 1 linker histone H1 and H5 family Spc7_N PF15402.6 OEU18733.1 - 0.4 8.9 24.2 0.46 8.7 24.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RR_TM4-6 PF06459.12 OEU18733.1 - 5.2 6.8 24.1 6.6 6.5 24.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 4HBT PF03061.22 OEU18734.1 - 9.8e-17 61.1 0.1 1.5e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Syja_N PF02383.18 OEU18735.1 - 9.7e-76 255.1 0.1 1.3e-75 254.7 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain WYL PF13280.6 OEU18735.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 WYL domain Melibiase_C PF17801.1 OEU18738.1 - 4.7e-09 36.2 0.2 1.5e-08 34.6 0.2 1.8 1 1 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Sid-5 PF17204.3 OEU18738.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Sid-5 family Abhydrolase_6 PF12697.7 OEU18739.1 - 3.5e-20 73.5 0.0 4.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU18739.1 - 3e-16 59.9 0.0 1.8e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU18739.1 - 5.1e-10 39.0 0.0 1.4e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OEU18739.1 - 0.0095 15.5 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 OEU18739.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.16 OEU18739.1 - 0.14 11.9 0.0 5.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OEU18739.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold zf-TRAF PF02176.18 OEU18740.1 - 8.4e-14 52.0 16.5 4.1e-10 40.2 7.1 3.9 3 1 2 5 5 5 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 OEU18740.1 - 6.7e-07 29.7 17.5 4.7e-05 23.8 8.1 2.6 2 1 1 3 3 3 2 TRAF-like zinc-finger Sina PF03145.16 OEU18740.1 - 6e-05 23.1 9.7 0.0014 18.6 0.7 2.7 1 1 1 2 2 2 2 Seven in absentia protein family Prefoldin_2 PF01920.20 OEU18740.1 - 0.0031 17.4 2.0 0.0047 16.9 2.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Fzo_mitofusin PF04799.13 OEU18740.1 - 0.023 14.2 2.4 0.037 13.6 2.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region bZIP_1 PF00170.21 OEU18740.1 - 0.028 14.5 1.2 0.028 14.5 1.2 2.1 1 1 1 2 2 2 0 bZIP transcription factor Herpes_BLRF2 PF05812.12 OEU18740.1 - 0.041 14.0 1.4 0.067 13.3 1.4 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 OEU18740.1 - 0.054 13.8 1.2 0.12 12.7 1.0 1.7 1 1 0 1 1 1 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 OEU18740.1 - 0.49 10.4 7.9 2.3 8.3 7.4 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MAPKK1_Int PF08923.10 OEU18741.1 - 1.6e-09 37.6 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DUF1517 PF07466.11 OEU18741.1 - 0.078 13.1 0.2 0.85 9.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1517) Rieske_2 PF13806.6 OEU18742.1 - 9.3e-19 67.3 0.0 1.1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 OEU18742.1 - 0.0094 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_11 PF08241.12 OEU18743.1 - 7.4e-09 36.2 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU18743.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OEU18743.1 - 3.1e-05 24.6 0.0 7.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU18743.1 - 0.00091 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 OEU18743.1 - 0.0057 17.4 0.0 0.02 15.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU18743.1 - 0.0097 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU18743.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DRE2_N PF16803.5 OEU18743.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus NNMT_PNMT_TEMT PF01234.17 OEU18743.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family ADH_zinc_N_2 PF13602.6 OEU18743.1 - 0.08 14.0 0.0 0.16 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1240 PF06836.12 OEU18745.1 - 0.021 15.3 0.1 0.034 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) LRRC37AB_C PF14914.6 OEU18745.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DHHC PF01529.20 OEU18746.1 - 1.2e-14 54.6 0.0 1.2e-14 54.6 0.0 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 OEU18747.1 - 2.4e-11 43.9 0.5 6.6e-11 42.5 0.0 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase ExoD PF06055.12 OEU18747.1 - 0.042 13.2 2.4 0.081 12.3 2.4 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD zinc_ribbon_4 PF13717.6 OEU18748.1 - 0.0033 17.3 0.1 0.0033 17.3 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zf-UDP PF14569.6 OEU18748.1 - 0.006 16.7 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Zn_Tnp_IS1595 PF12760.7 OEU18748.1 - 0.14 12.1 0.2 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.6 OEU18748.1 - 0.32 10.8 3.1 0.38 10.6 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OEU18748.1 - 0.68 9.4 4.3 1 8.8 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Syntaxin-6_N PF09177.11 OEU18749.1 - 2e-15 57.1 3.1 2e-15 57.1 3.1 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 OEU18749.1 - 0.00025 21.0 5.2 0.00086 19.3 0.1 3.3 3 1 0 3 3 3 1 SNARE domain Cep57_CLD_2 PF14197.6 OEU18749.1 - 0.0024 17.9 8.7 2.5 8.2 0.1 4.5 4 0 0 4 4 4 2 Centrosome localisation domain of PPC89 DUF2205 PF10224.9 OEU18749.1 - 0.017 15.1 2.3 0.11 12.5 1.6 2.5 1 1 1 2 2 2 0 Short coiled-coil protein KNOX2 PF03791.13 OEU18749.1 - 0.018 14.5 0.3 7.8 6.1 0.0 2.7 2 0 0 2 2 2 0 KNOX2 domain DUF5446 PF17522.2 OEU18749.1 - 0.057 13.6 0.6 0.43 10.8 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5446) DUF2207 PF09972.9 OEU18749.1 - 0.083 11.6 4.0 2 7.1 0.0 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF745 PF05335.13 OEU18749.1 - 0.14 11.9 5.5 0.045 13.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FliJ PF02050.16 OEU18749.1 - 0.14 12.4 6.0 1.5 9.0 0.2 2.8 2 1 0 3 3 3 0 Flagellar FliJ protein FPP PF05911.11 OEU18749.1 - 0.32 9.2 13.5 0.066 11.4 1.6 1.9 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 OEU18749.1 - 0.4 10.7 7.4 5.2 7.1 0.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OEU18749.1 - 0.54 10.6 5.0 15 5.9 0.4 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 OEU18749.1 - 1.6 9.2 6.9 6.2 7.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 GTP_EFTU PF00009.27 OEU18750.1 - 1.1e-23 83.8 0.0 2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OEU18750.1 - 8e-06 25.9 0.0 2.4e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU18750.1 - 5.4e-05 23.1 0.2 0.34 10.8 0.4 2.5 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 OEU18750.1 - 0.1 12.8 0.1 8.3 6.7 0.1 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 OEU18750.1 - 0.13 11.8 0.0 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 OEU18750.1 - 0.15 12.6 0.2 0.98 9.9 0.1 2.2 2 0 0 2 2 2 0 ABC transporter DUF2993 PF11209.8 OEU18751.1 - 0.078 13.2 0.0 0.096 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2993) DER1 PF04511.15 OEU18752.1 - 9.1e-19 68.1 0.7 1.2e-18 67.7 0.7 1.2 1 0 0 1 1 1 1 Der1-like family NAD_binding_10 PF13460.6 OEU18753.1 - 1.9e-39 135.5 0.1 3e-39 134.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OEU18753.1 - 1.3e-09 37.9 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OEU18753.1 - 4.5e-08 32.9 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OEU18753.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU18753.1 - 0.00052 19.1 0.7 0.00093 18.3 0.5 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OEU18753.1 - 0.087 13.3 0.1 0.52 10.8 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DED PF01335.21 OEU18754.1 - 0.01 16.1 2.7 0.01 16.1 2.7 2.2 3 0 0 3 3 3 0 Death effector domain CENP-F_leu_zip PF10473.9 OEU18754.1 - 0.017 15.1 5.4 0.017 15.1 5.4 3.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 OEU18754.1 - 3.7 7.9 24.6 9.7 6.6 2.5 4.1 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 OEU18754.1 - 5.5 7.7 22.3 0.083 13.6 1.8 3.9 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) WHEP-TRS PF00458.20 OEU18754.1 - 9 6.5 9.4 24 5.2 0.4 3.0 2 1 0 2 2 2 0 WHEP-TRS domain DENN PF02141.21 OEU18756.1 - 2.4e-26 92.8 0.8 2.4e-26 92.8 0.8 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain ENTH PF01417.20 OEU18756.1 - 1.9e-13 50.5 0.2 4e-13 49.5 0.2 1.6 1 0 0 1 1 1 1 ENTH domain uDENN PF03456.18 OEU18756.1 - 0.21 12.3 0.1 0.21 12.3 0.1 2.8 2 1 0 2 2 2 0 uDENN domain Thioredoxin_8 PF13905.6 OEU18757.1 - 6.4e-08 32.8 0.0 2.4e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OEU18757.1 - 0.002 18.1 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OEU18757.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Coq4 PF05019.13 OEU18759.1 - 5.1e-73 245.0 0.0 6.6e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pkinase PF00069.25 OEU18761.1 - 3.2e-62 210.3 0.0 5.1e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU18761.1 - 2.2e-47 161.5 0.0 5e-47 160.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU18761.1 - 6.4e-06 25.2 0.0 5.3e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 OEU18761.1 - 0.014 15.6 1.1 0.033 14.4 0.0 2.1 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 OEU18761.1 - 0.094 12.0 0.0 7.1 5.8 0.0 2.5 2 1 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OEU18761.1 - 0.82 8.5 3.2 3.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Haspin like kinase domain PIEZO PF15917.5 OEU18761.1 - 7.3 6.0 7.5 0.16 11.4 0.3 1.8 2 0 0 2 2 2 0 Piezo DUF4834 PF16118.5 OEU18762.1 - 0.025 15.5 1.0 0.025 15.5 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 OEU18762.1 - 1 8.1 8.7 1.2 7.8 8.7 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 OEU18762.1 - 1.5 8.4 13.2 1.9 8.0 13.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF4199 PF13858.6 OEU18762.1 - 1.8 9.0 5.3 4.2 7.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2722 PF10846.8 OEU18762.1 - 7 5.5 12.6 9.3 5.1 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DRTGG PF07085.12 OEU18763.1 - 0.0018 18.0 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 DRTGG domain RVT_3 PF13456.6 OEU18764.1 - 4.9e-20 71.6 0.0 5.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 OEU18764.1 - 2.3e-06 27.8 0.0 3.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Baculo_PEP_C PF04513.12 OEU18764.1 - 0.0071 16.4 0.4 0.0098 15.9 0.4 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus UCH PF00443.29 OEU18766.1 - 2.5e-67 227.1 0.0 2.8e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU18766.1 - 2.3e-11 43.9 0.0 5.8e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4279 PF14106.6 OEU18766.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) Peptidase_C98 PF15499.6 OEU18766.1 - 0.077 12.5 1.5 4.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF5643 PF18705.1 OEU18766.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Tetraspanin PF00335.20 OEU18766.1 - 0.16 11.6 0.4 0.21 11.2 0.4 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF5089 PF17002.5 OEU18767.1 - 0.0076 16.1 7.9 0.012 15.5 7.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) Myb_DNA-binding PF00249.31 OEU18768.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain GFO_IDH_MocA PF01408.22 OEU18769.1 - 2e-12 48.0 0.0 3.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OEU18769.1 - 4.4e-06 26.7 0.0 9.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Aldo_ket_red PF00248.21 OEU18770.1 - 3.9e-36 124.8 0.0 4.8e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Xol-1_GHMP-like PF09109.10 OEU18770.1 - 0.08 12.8 0.2 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Switch protein XOL-1, GHMP-like DUF4864 PF16156.5 OEU18771.1 - 3.5e-05 24.4 0.0 4.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4864) LRR_4 PF12799.7 OEU18772.1 - 5.1e-17 61.7 32.1 0.0021 18.4 0.1 7.5 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU18772.1 - 3.8e-16 58.6 24.4 4.3e-06 26.4 0.8 5.6 2 2 3 6 6 6 6 Leucine rich repeat ptaRNA1_toxin PF12703.7 OEU18772.1 - 0.24 11.5 0.0 22 5.2 0.0 3.4 3 1 1 4 4 4 0 Toxin of toxin-antitoxin type 1 system LRR_1 PF00560.33 OEU18772.1 - 0.85 10.4 38.0 5.3 8.0 0.0 9.6 10 1 0 10 10 10 0 Leucine Rich Repeat PTPLA PF04387.14 OEU18773.1 - 1.8e-09 37.5 0.5 2.7e-09 37.0 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA MatE PF01554.18 OEU18774.1 - 2.4e-19 69.6 24.9 9.7e-17 61.1 8.1 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU18774.1 - 1.2e-05 25.3 6.5 1.2e-05 25.3 6.5 3.6 2 1 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain TMEM70 PF06979.12 OEU18774.1 - 0.013 15.9 4.8 0.04 14.3 0.3 2.7 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex CRCB PF02537.15 OEU18775.1 - 5.8e-21 74.6 11.9 1.3e-11 44.7 4.3 3.3 3 0 0 3 3 3 3 CrcB-like protein, Camphor Resistance (CrcB) MMR1 PF08505.10 OEU18775.1 - 0.028 14.7 15.2 0.35 11.1 8.2 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Tim17 PF02466.19 OEU18777.1 - 3.1e-14 53.3 4.9 4.7e-14 52.7 4.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pam17 PF08566.10 OEU18777.1 - 0.36 10.7 1.4 1 9.2 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 RINGv PF12906.7 OEU18778.1 - 1e-07 31.9 4.5 1e-07 31.9 4.5 3.3 4 0 0 4 4 4 1 RING-variant domain zf-MYND PF01753.18 OEU18778.1 - 9e-05 22.5 17.2 9e-05 22.5 17.2 2.4 2 0 0 2 2 2 1 MYND finger Nup153 PF08604.10 OEU18778.1 - 2.6 6.7 6.6 0.13 11.1 1.1 1.5 2 0 0 2 2 2 0 Nucleoporin Nup153-like ArfGap PF01412.18 OEU18779.1 - 8.9e-25 87.0 0.5 9.2e-25 87.0 0.5 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-LYAR PF08790.11 OEU18779.1 - 0.0074 16.2 1.9 1.8 8.5 0.1 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger Ank_2 PF12796.7 OEU18780.1 - 0.0031 18.1 0.6 0.0077 16.8 0.4 1.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU18780.1 - 0.0043 17.6 0.3 1.1 9.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU18780.1 - 0.018 15.5 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat KxDL PF10241.9 OEU18782.1 - 0.083 13.2 0.3 0.16 12.3 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Myb_DNA-binding PF00249.31 OEU18783.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU18783.1 - 0.011 15.5 1.9 0.014 15.2 0.0 2.2 2 0 0 2 2 2 0 Myb DNA-binding like Cyclin_C PF02984.19 OEU18783.1 - 0.5 10.5 3.7 1.7 8.7 3.5 2.1 1 1 1 2 2 2 0 Cyclin, C-terminal domain Radical_SAM PF04055.21 OEU18784.1 - 1.3e-32 113.5 0.1 4.1e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 OEU18784.1 - 3.2e-23 81.6 0.0 8.4e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 OEU18784.1 - 9.9e-11 41.5 1.1 1.3e-10 41.1 0.2 1.7 2 0 0 2 2 2 1 TRAM domain TRAM_2 PF18693.1 OEU18784.1 - 0.03 14.5 0.3 0.24 11.6 0.3 2.5 1 1 0 1 1 1 0 TRAM domain Lipase_GDSL_2 PF13472.6 OEU18784.1 - 0.1 13.0 0.0 0.47 10.8 0.0 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Rotamase_3 PF13616.6 OEU18785.1 - 4.8e-09 36.8 0.1 4.7e-08 33.6 0.1 2.1 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OEU18785.1 - 1.1e-07 32.7 0.0 2.2e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU18785.1 - 0.0023 18.7 0.0 0.0036 18.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Mg-por_mtran_C PF07109.11 OEU18786.1 - 1.6e-34 118.1 0.0 8e-34 115.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 OEU18786.1 - 1.1e-12 48.5 0.1 3.4e-12 46.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU18786.1 - 3.6e-10 39.8 0.0 6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU18786.1 - 6e-10 39.2 0.0 9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU18786.1 - 3e-08 34.3 0.0 1.1e-07 32.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU18786.1 - 3e-07 31.0 0.1 6.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU18786.1 - 1.2e-05 24.7 0.2 2.5e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 OEU18786.1 - 1.8e-05 24.7 0.4 0.0032 17.4 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU18786.1 - 4.6e-05 23.5 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU18786.1 - 4.9e-05 22.9 0.1 7.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU18786.1 - 7e-05 22.4 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OEU18786.1 - 0.00028 20.3 0.1 0.00081 18.8 0.0 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 OEU18786.1 - 0.0019 17.2 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Mur_ligase PF01225.25 OEU18786.1 - 0.01 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, catalytic domain NodS PF05401.11 OEU18786.1 - 0.047 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF43 PF01861.16 OEU18786.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_4 PF02390.17 OEU18786.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Pantoate_ligase PF02569.15 OEU18787.1 - 2.8e-89 298.9 0.0 3.2e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PALP PF00291.25 OEU18788.1 - 1.1e-77 261.4 3.5 1.3e-77 261.1 3.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OEU18788.1 - 1.2e-37 127.6 0.0 1.4e-20 72.8 0.0 2.8 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Mad3_BUB1_I PF08311.12 OEU18790.1 - 7.1e-31 106.8 0.0 1.1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Rhodanese PF00581.20 OEU18791.1 - 8.7e-06 26.2 0.0 2.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Methyltransf_25 PF13649.6 OEU18792.1 - 1.3e-13 51.4 0.0 3.6e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU18792.1 - 6.6e-12 45.9 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU18792.1 - 6.6e-09 36.4 0.0 1.5e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU18792.1 - 7.5e-09 35.3 0.1 1.3e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU18792.1 - 1.9e-08 34.2 0.0 2.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU18792.1 - 2.4e-05 24.3 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OEU18792.1 - 0.00086 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OEU18792.1 - 0.0027 17.3 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OEU18792.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 OEU18792.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 OEU18792.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 OEU18792.1 - 0.12 12.2 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF883 PF05957.13 OEU18793.1 - 0.0087 16.6 7.2 0.024 15.2 5.0 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Metallophos_3 PF14582.6 OEU18793.1 - 0.016 14.6 0.7 0.023 14.0 0.6 1.4 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Phage_lysis PF03245.13 OEU18793.1 - 0.029 14.5 11.9 0.21 11.7 6.9 2.5 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein AAA_13 PF13166.6 OEU18793.1 - 0.17 10.5 10.3 0.21 10.2 10.3 1.1 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 OEU18793.1 - 0.18 11.2 15.2 0.26 10.6 15.2 1.3 1 1 0 1 1 1 0 FAM76 protein Gsf2 PF11055.8 OEU18793.1 - 0.18 10.5 6.2 0.27 9.9 6.2 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 Exonuc_VII_L PF02601.15 OEU18793.1 - 0.24 10.9 8.4 0.29 10.7 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 OEU18793.1 - 0.25 10.2 15.1 0.4 9.5 14.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF148 PF02520.17 OEU18793.1 - 0.33 11.1 10.2 0.45 10.6 7.8 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF4407 PF14362.6 OEU18793.1 - 1.1 8.6 7.7 1.4 8.2 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 OEU18793.1 - 2.1 8.4 11.8 0.34 10.9 5.9 2.1 1 1 2 3 3 3 0 FlxA-like protein DUF1515 PF07439.11 OEU18793.1 - 4.8 7.3 7.8 1.2 9.2 4.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) Cyclin_N PF00134.23 OEU18794.1 - 0.00029 20.6 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.7 OEU18796.1 - 0.14 12.8 0.0 20 5.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) FAD_binding_3 PF01494.19 OEU18797.1 - 4e-12 46.1 0.8 2.8e-09 36.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain PrsW-protease PF13367.6 OEU18798.1 - 0.0024 17.3 4.9 0.0031 17.0 0.8 2.8 2 1 0 2 2 2 1 PrsW family intramembrane metalloprotease LtrA PF06772.11 OEU18798.1 - 0.011 15.0 0.9 0.011 15.0 0.9 2.2 3 0 0 3 3 3 0 Bacterial low temperature requirement A protein (LtrA) Metallophos PF00149.28 OEU18799.1 - 3.5e-35 122.4 0.0 4.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OEU18799.1 - 1.4e-16 60.7 0.0 2.2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Cpn60_TCP1 PF00118.24 OEU18800.1 - 1.5e-145 485.6 13.3 1.7e-145 485.4 13.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lin0512_fam PF09585.10 OEU18801.1 - 1.8e-35 121.4 0.0 2.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) 3HCDH_N PF02737.18 OEU18802.1 - 2.4e-54 184.0 0.2 3.8e-54 183.3 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 OEU18802.1 - 2.3e-36 125.4 0.1 1.3e-35 122.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 OEU18802.1 - 4e-30 104.3 0.0 1.6e-19 70.3 0.0 3.0 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 OEU18802.1 - 2e-21 76.8 0.0 3.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 OEU18802.1 - 0.0023 18.1 0.1 0.0064 16.7 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2680 PF10925.8 OEU18802.1 - 0.028 14.4 0.1 0.95 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) ApbA PF02558.16 OEU18802.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OEU18802.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OEU18802.1 - 0.22 10.7 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.25 OEU18803.1 - 9e-33 113.4 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU18803.1 - 1.2e-17 64.3 0.0 1.5e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU18803.1 - 3e-10 40.3 0.0 8.4e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 KR domain LRR_6 PF13516.6 OEU18805.1 - 1.8e-23 80.5 5.8 0.00015 21.5 0.1 6.5 6 1 1 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 OEU18805.1 - 1.4e-08 34.9 1.3 0.0037 17.6 0.1 4.2 1 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU18805.1 - 2.2e-06 27.4 1.6 16 6.5 0.0 5.6 4 2 0 4 4 4 2 Leucine Rich Repeat SAM_Ste50p PF09235.10 OEU18805.1 - 2.1e-05 24.7 9.9 1.8 8.9 0.2 5.5 1 1 5 6 6 6 2 Ste50p, sterile alpha motif LRR_8 PF13855.6 OEU18805.1 - 0.014 15.1 0.0 0.46 10.3 0.0 3.2 3 1 0 3 3 3 0 Leucine rich repeat POTRA_1 PF08478.10 OEU18805.1 - 0.023 15.0 0.0 3.1 8.2 0.0 3.3 3 1 1 4 4 4 0 POTRA domain, FtsQ-type CagY_M PF07337.11 OEU18805.1 - 0.044 13.4 1.3 62 3.3 0.0 4.2 5 0 0 5 5 5 0 DC-EC Repeat BTB PF00651.31 OEU18806.1 - 1.7e-12 47.6 0.3 6.4e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Nop PF01798.18 OEU18806.1 - 0.032 13.7 0.2 0.47 9.9 0.1 2.1 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin Atthog PF18800.1 OEU18807.1 - 0.36 10.7 10.9 0.48 10.3 10.9 1.3 1 1 0 1 1 1 0 Attenuator of Hedgehog Oxidored_q3 PF00499.20 OEU18807.1 - 8 6.2 24.0 10 5.9 24.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 XhlA PF10779.9 OEU18808.1 - 0.087 13.0 0.1 0.3 11.3 0.1 1.9 1 0 0 1 1 1 0 Haemolysin XhlA HNH_2 PF13391.6 OEU18808.1 - 0.11 12.6 0.1 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease ABC_tran_CTD PF16326.5 OEU18808.1 - 0.3 11.4 2.1 0.71 10.2 0.4 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-RING_2 PF13639.6 OEU18809.1 - 5.5e-09 36.2 18.2 9.5e-09 35.5 18.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU18809.1 - 4.4e-06 26.3 11.6 1.1e-05 25.1 11.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU18809.1 - 6.7e-05 23.1 13.3 0.00014 22.1 13.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rho_N PF07498.12 OEU18809.1 - 0.0002 21.2 0.7 0.77 9.7 0.0 4.6 5 0 0 5 5 5 1 Rho termination factor, N-terminal domain zf-C3HC4_2 PF13923.6 OEU18809.1 - 0.0011 18.8 16.9 0.0019 18.0 16.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU18809.1 - 0.0061 16.6 5.0 0.012 15.7 5.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OEU18809.1 - 0.0099 15.7 17.7 0.019 14.8 17.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU18809.1 - 0.029 14.2 14.1 0.047 13.6 14.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU18809.1 - 0.11 12.5 12.4 0.08 13.0 10.2 2.0 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 OEU18809.1 - 0.79 9.9 11.2 2.7 8.2 11.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU18809.1 - 0.96 9.5 15.7 1.6 8.7 15.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OEU18809.1 - 1 9.0 12.8 1.9 8.2 12.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HIG_1_N PF04588.13 OEU18810.1 - 9.2e-18 64.2 0.3 1.7e-17 63.4 0.3 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PilP PF04351.13 OEU18810.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilP Beta_helix PF13229.6 OEU18811.1 - 4.7e-12 46.0 44.0 0.00016 21.6 24.1 3.2 2 1 1 3 3 3 3 Right handed beta helix region TauD PF02668.16 OEU18812.1 - 2.5e-30 106.2 0.0 4e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OEU18812.1 - 0.036 13.2 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 CsiD HrpJ PF07201.11 OEU18813.1 - 3.8 7.8 16.3 0.12 12.7 8.9 2.2 2 0 0 2 2 2 0 HrpJ-like domain NYN PF01936.18 OEU18815.1 - 1.7e-13 51.3 0.1 1.5e-12 48.2 0.1 2.3 1 1 0 1 1 1 1 NYN domain SAP PF02037.27 OEU18815.1 - 3.4e-07 29.9 0.1 9.6e-07 28.4 0.1 1.8 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 OEU18815.1 - 0.033 14.1 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain MeaB PF03308.16 OEU18815.1 - 0.053 12.5 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PPR_2 PF13041.6 OEU18816.1 - 1.6e-20 73.0 10.1 1.3e-06 28.5 0.0 8.2 5 3 4 9 9 9 6 PPR repeat family PPR_3 PF13812.6 OEU18816.1 - 8.4e-20 70.6 0.7 0.0017 18.4 0.1 8.0 4 2 3 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU18816.1 - 3.2e-17 61.9 0.1 0.047 13.4 0.0 8.4 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 OEU18816.1 - 2.8e-11 43.2 3.3 0.00014 21.3 0.2 4.2 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OEU18816.1 - 6.1e-05 23.0 21.2 1 9.8 0.0 9.9 9 3 0 9 9 9 2 PPR repeat DUF3168 PF11367.8 OEU18816.1 - 0.02 15.1 0.1 0.71 10.1 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3168) DRE2_N PF16803.5 OEU18817.1 - 0.43 10.8 4.4 10 6.4 0.1 2.7 1 1 1 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus DUF4834 PF16118.5 OEU18817.1 - 1.1 10.3 0.1 1.1 10.3 0.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) Ribosomal_L5_C PF00673.21 OEU18818.1 - 9.3e-22 77.0 0.1 1.6e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OEU18818.1 - 7.1e-19 67.9 0.0 2.7e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 OEU18818.1 - 0.014 15.1 0.5 0.025 14.3 0.1 1.5 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DUF3791 PF12668.7 OEU18820.1 - 0.066 13.3 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Glyco_transf_15 PF01793.16 OEU18821.1 - 7.2e-18 64.9 17.3 7.2e-18 64.9 17.3 2.0 2 1 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase UEV PF05743.13 OEU18822.1 - 6.1e-24 84.2 1.0 8.7e-24 83.7 0.1 1.7 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 OEU18822.1 - 1.5e-17 63.3 0.2 2.8e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 OEU18822.1 - 2.6e-05 23.9 1.6 3.3e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Amidohydro_1 PF01979.20 OEU18822.1 - 0.088 12.1 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Amidohydrolase family UBA2_C PF16195.5 OEU18822.1 - 0.39 11.4 7.6 0.27 11.9 6.1 1.6 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DOR PF14839.6 OEU18822.1 - 5.6 6.8 19.6 0.49 10.3 10.8 2.1 1 1 1 2 2 2 0 DOR family EMP24_GP25L PF01105.24 OEU18823.1 - 2.1e-19 70.2 0.7 4.7e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD BDHCT_assoc PF16204.5 OEU18824.1 - 0.00053 19.7 1.1 0.0018 18.0 1.1 1.9 1 0 0 1 1 1 1 BDHCT-box associated domain on Bloom syndrome protein SpdB PF05122.13 OEU18824.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Mobile element transfer protein 4HBT_3 PF13622.6 OEU18824.1 - 4.2 7.6 6.1 0.32 11.2 0.4 2.0 2 0 0 2 2 2 0 Thioesterase-like superfamily SUIM_assoc PF16619.5 OEU18824.1 - 9.4 6.4 21.7 0.38 10.8 0.2 3.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 UPF0051 PF01458.17 OEU18828.1 - 6.7e-33 114.2 0.0 7.8e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Cellulase PF00150.18 OEU18829.1 - 4.8e-07 29.5 7.2 7.5e-07 28.8 7.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP2 PF00847.20 OEU18830.1 - 4.8e-06 26.7 0.2 4.8e-06 26.7 0.2 2.1 2 0 0 2 2 2 1 AP2 domain MIase PF02426.16 OEU18830.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Muconolactone delta-isomerase DUF2188 PF09954.9 OEU18830.1 - 0.36 11.0 0.1 0.36 11.0 0.1 3.4 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Lipase PF00151.19 OEU18831.1 - 2.1e-08 33.9 0.5 3e-08 33.4 0.0 1.4 2 0 0 2 2 2 1 Lipase DUF676 PF05057.14 OEU18831.1 - 0.02 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) SUIM_assoc PF16619.5 OEU18831.1 - 9.6 6.4 13.3 1.7e+02 2.3 12.1 3.1 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Thioredoxin PF00085.20 OEU18833.1 - 9.8e-08 31.9 0.1 7e-07 29.2 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU18833.1 - 0.00054 20.2 0.0 0.00076 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU18833.1 - 0.013 16.0 0.0 0.036 14.5 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain COX16 PF14138.6 OEU18834.1 - 0.00026 21.4 0.0 0.00026 21.4 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 YchF-GTPase_C PF06071.13 OEU18835.1 - 8.6e-37 125.2 0.5 2.1e-36 124.0 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OEU18835.1 - 1.5e-20 73.4 0.0 4e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU18835.1 - 7.5e-06 25.5 0.1 1.9e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 OEU18835.1 - 0.022 13.7 0.0 0.22 10.5 0.0 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LRR_8 PF13855.6 OEU18837.1 - 2.2e-09 37.0 1.6 1.8e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 OEU18837.1 - 3.2e-08 33.0 0.3 1.1 10.1 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.7 OEU18837.1 - 6.3e-06 26.4 2.4 0.051 14.0 0.2 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) DUF4148 PF13663.6 OEU18838.1 - 0.05 13.8 0.9 0.073 13.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) UPF0180 PF03698.13 OEU18839.1 - 0.086 13.0 0.7 0.2 11.8 0.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0180) GOLD_2 PF13897.6 OEU18839.1 - 0.78 10.2 4.0 0.43 11.1 1.1 1.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking SDA1 PF05285.12 OEU18839.1 - 1.7 8.0 5.9 0.68 9.3 3.9 1.3 1 1 0 1 1 1 0 SDA1 HSF_DNA-bind PF00447.17 OEU18840.1 - 5.6e-21 75.0 0.5 1.9e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding TraH PF06122.11 OEU18840.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Ribosomal_S13 PF00416.22 OEU18841.1 - 3.8e-49 166.3 1.4 4.3e-49 166.1 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 OEU18841.1 - 0.0085 16.3 0.3 0.025 14.8 0.1 1.9 2 1 0 2 2 2 1 Helix-hairpin-helix motif FbpA PF05833.11 OEU18841.1 - 0.025 13.4 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PHF12_MRG_bd PF16737.5 OEU18841.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain Sel_put PF04328.13 OEU18842.1 - 0.033 14.2 0.1 0.086 12.9 0.0 1.7 2 0 0 2 2 2 0 Selenoprotein, putative Cytochrom_D1 PF02239.16 OEU18843.1 - 0.073 11.6 0.1 0.096 11.2 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Smr PF01713.21 OEU18844.1 - 5.6e-07 29.8 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Smr domain LRAT PF04970.13 OEU18845.1 - 1.5e-07 31.7 0.1 2.6e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase MRP-S33 PF08293.11 OEU18847.1 - 4.1e-10 39.7 0.7 6.1e-10 39.2 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MTHFR PF02219.17 OEU18848.1 - 1e-98 330.2 0.0 2.6e-98 328.9 0.0 1.5 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.16 OEU18849.1 - 2.8e-12 46.3 27.3 2.8e-12 46.3 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF997 PF06196.12 OEU18849.1 - 3.3 7.8 13.3 0.66 10.0 7.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) FeoB_associated PF12669.7 OEU18849.1 - 3.9 8.0 6.1 23 5.5 1.3 2.9 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Aa_trans PF01490.18 OEU18850.1 - 4.4e-49 167.3 19.6 5.8e-49 166.9 19.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ICMT PF04140.14 OEU18850.1 - 0.081 13.4 0.6 2.1 8.8 0.8 2.8 1 1 1 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_23 PF13489.6 OEU18851.1 - 0.00095 19.0 0.0 0.0014 18.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OEU18851.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase Aldo_ket_red PF00248.21 OEU18852.1 - 2.6e-49 168.0 0.0 4.8e-49 167.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Phage_rep_org_N PF09681.10 OEU18852.1 - 0.0052 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal phage replisome organiser (Phage_rep_org_N) NUDIX PF00293.28 OEU18853.1 - 2.9e-08 33.8 0.0 6.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Aminotran_5 PF00266.19 OEU18854.1 - 5.5e-10 38.7 0.0 6.7e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 OEU18854.1 - 0.0034 16.6 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SUIM_assoc PF16619.5 OEU18854.1 - 2.1 8.5 6.7 1.6 8.8 4.4 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 OTCace PF00185.24 OEU18855.1 - 1.5e-54 184.4 0.5 2.1e-54 183.8 0.5 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OEU18855.1 - 2.4e-36 125.0 0.1 3.8e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Gly_rich PF12810.7 OEU18856.1 - 4.5e-05 23.5 2.6 7e-05 22.9 2.6 1.3 1 0 0 1 1 1 1 Glycine rich protein Serglycin PF04360.12 OEU18856.1 - 0.12 12.3 2.7 0.33 10.9 2.7 1.8 1 0 0 1 1 1 0 Serglycin BioT2 PF15368.6 OEU18856.1 - 1.9 8.4 7.0 49 3.8 7.0 2.5 1 1 0 1 1 1 0 Spermatogenesis family BioT2 Met_synt_B12 PF02965.17 OEU18857.1 - 8.2e-108 360.0 0.0 1.6e-107 359.1 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.22 OEU18857.1 - 4.7e-45 154.2 0.1 1.1e-44 152.9 0.1 1.7 1 0 0 1 1 1 1 Pterin binding enzyme S-methyl_trans PF02574.16 OEU18857.1 - 1.7e-29 103.5 0.0 3.6e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase B12-binding_2 PF02607.17 OEU18857.1 - 4.6e-25 87.8 0.2 1.3e-24 86.4 0.2 1.9 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 OEU18857.1 - 5e-20 71.7 0.1 3e-18 66.0 0.1 2.6 2 0 0 2 2 2 1 B12 binding domain GNT-I PF03071.15 OEU18857.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 GNT-I family UQ_con PF00179.26 OEU18858.1 - 8.7e-33 112.9 0.0 1.1e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU18858.1 - 0.055 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CtaG_Cox11 PF04442.14 OEU18859.1 - 2.4e-59 199.7 0.3 2.8e-59 199.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 KH_1 PF00013.29 OEU18861.1 - 3.4e-41 138.9 0.6 5.5e-13 48.5 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OEU18861.1 - 2.1e-09 37.1 0.3 0.055 13.3 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OEU18861.1 - 2e-07 30.8 0.6 0.034 14.0 0.0 3.4 3 0 0 3 3 3 3 KH domain LRR_4 PF12799.7 OEU18862.1 - 0.0042 17.5 6.6 0.075 13.5 0.2 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU18862.1 - 0.053 13.3 2.0 0.33 10.7 0.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat SAM_3 PF18016.1 OEU18862.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1725 PF08333.11 OEU18862.1 - 0.24 11.1 0.1 0.24 11.1 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1725) RNase_H2_suC PF08615.11 OEU18863.1 - 1.1e-08 35.4 1.3 3.7e-08 33.6 1.3 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Colicin-DNase PF12639.7 OEU18863.1 - 0.029 15.2 1.0 0.046 14.5 1.0 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin TPT PF03151.16 OEU18864.1 - 7.2e-35 120.7 24.7 9.1e-35 120.4 24.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OEU18864.1 - 8.9e-06 25.1 23.4 1.9e-05 24.0 21.2 2.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU18864.1 - 0.0014 18.8 27.6 0.11 12.7 8.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family Methylase_S PF01420.19 OEU18864.1 - 0.2 11.9 0.4 0.94 9.7 0.0 2.1 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain PPR_2 PF13041.6 OEU18865.1 - 3.3e-08 33.6 0.0 0.0032 17.6 0.0 3.0 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 OEU18865.1 - 6.7e-07 29.3 0.0 0.075 13.1 0.2 3.5 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU18865.1 - 0.0021 17.7 0.1 6.4 6.6 0.0 4.4 5 0 0 5 5 5 1 PPR repeat PPR PF01535.20 OEU18865.1 - 0.13 12.6 2.8 53 4.4 0.1 4.2 5 1 0 5 5 5 0 PPR repeat LRR_8 PF13855.6 OEU18866.1 - 9.9e-10 38.0 11.8 0.047 13.5 2.7 5.1 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OEU18866.1 - 8.1e-09 35.6 12.9 0.00063 20.1 0.8 5.6 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU18866.1 - 0.0002 21.4 8.0 69 4.6 0.0 7.1 8 1 0 8 8 8 0 Leucine Rich Repeat LRRNT_2 PF08263.12 OEU18866.1 - 0.4 11.0 2.8 0.96 9.8 2.8 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain TRAM_LAG1_CLN8 PF03798.16 OEU18867.1 - 2.7e-11 43.6 17.6 4.6e-11 42.8 17.6 1.4 1 0 0 1 1 1 1 TLC domain DUF1645 PF07816.11 OEU18867.1 - 0.41 11.2 5.6 0.84 10.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) MMR_HSR1 PF01926.23 OEU18868.1 - 1.2e-41 141.4 0.4 1.6e-20 73.3 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 OEU18868.1 - 1.2e-21 76.8 0.1 2.4e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 OEU18868.1 - 9.2e-21 74.0 0.2 8.5e-13 48.1 0.3 2.8 2 2 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 OEU18868.1 - 1e-18 67.6 0.4 2.6e-10 40.2 0.1 5.1 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OEU18868.1 - 9.9e-10 38.7 1.3 0.0009 19.3 0.0 4.4 3 1 1 4 4 4 2 Dynamin family Roc PF08477.13 OEU18868.1 - 1e-08 35.4 2.1 0.018 15.3 0.1 4.1 3 1 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OEU18868.1 - 3.8e-08 33.0 0.2 0.0035 16.8 0.1 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 OEU18868.1 - 9.8e-08 31.6 0.4 0.2 11.1 0.0 3.5 3 0 0 3 3 3 3 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OEU18868.1 - 2.1e-07 31.0 1.0 0.021 14.8 0.1 3.5 3 0 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 OEU18868.1 - 1.2e-06 28.0 0.1 2.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 AIG1 family TniB PF05621.11 OEU18868.1 - 4.5e-05 22.9 0.0 0.048 13.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein ABC_tran PF00005.27 OEU18868.1 - 6.1e-05 23.6 0.6 0.38 11.3 0.2 2.7 2 1 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 OEU18868.1 - 8.4e-05 22.9 0.4 0.51 10.6 0.0 3.2 2 1 1 3 3 3 2 AAA domain Ras PF00071.22 OEU18868.1 - 0.00011 21.8 0.1 0.01 15.4 0.0 3.2 2 1 0 2 2 2 1 Ras family AAA_18 PF13238.6 OEU18868.1 - 0.00013 22.5 0.0 0.66 10.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain Septin PF00735.18 OEU18868.1 - 0.00082 18.7 0.0 0.79 8.9 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_28 PF13521.6 OEU18868.1 - 0.0017 18.7 0.1 1.7 8.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OEU18868.1 - 0.0021 17.7 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU18868.1 - 0.0029 18.0 0.6 0.72 10.2 0.1 2.7 2 2 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 OEU18868.1 - 0.005 15.9 0.1 4.9 6.1 0.0 3.6 3 1 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OEU18868.1 - 0.0055 17.1 0.0 6.1 7.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 OEU18868.1 - 0.0088 15.8 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OEU18868.1 - 0.022 14.7 0.2 6.6 6.6 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.6 OEU18868.1 - 0.033 14.2 0.1 4.6 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OEU18868.1 - 0.055 12.6 0.1 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 OEU18868.1 - 0.059 13.1 0.0 34 4.1 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 OEU18868.1 - 0.063 13.2 0.0 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OEU18868.1 - 0.067 13.3 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain T4-gp15_tss PF16724.5 OEU18868.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 T4-like virus Myoviridae tail sheath stabiliser Vps52 PF04129.12 OEU18869.1 - 3.8e-90 303.1 2.9 5.9e-90 302.4 2.9 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OEU18869.1 - 4e-08 32.1 9.2 0.0002 20.0 1.0 3.3 2 1 0 2 2 2 2 Exocyst complex component Sec3 NitrOD5 PF11537.8 OEU18869.1 - 0.012 15.7 0.0 0.065 13.4 0.0 2.3 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 CTK3 PF12243.8 OEU18869.1 - 0.053 13.5 1.7 1.6 8.8 0.3 2.6 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Rick_17kDa_Anti PF05433.15 OEU18870.1 - 2.2e-05 24.2 52.6 0.0044 16.8 4.0 6.0 6 1 0 6 6 6 4 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 OEU18870.1 - 7.4 6.4 49.9 1 9.1 2.6 6.2 5 2 0 5 5 5 0 YMGG-like Gly-zipper dsrm PF00035.26 OEU18872.1 - 4.2e-09 37.0 0.0 4e-05 24.3 0.0 3.3 2 1 0 2 2 2 2 Double-stranded RNA binding motif F5_F8_type_C PF00754.25 OEU18873.1 - 0.00012 22.1 0.8 0.00075 19.6 0.2 2.2 2 0 0 2 2 2 1 F5/8 type C domain DFRP_C PF16543.5 OEU18875.1 - 1.2e-10 41.7 0.9 1.2e-10 41.7 0.9 2.9 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 ABC_tran PF00005.27 OEU18876.1 - 7.4e-34 117.2 0.0 1.4e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OEU18876.1 - 4.7e-27 95.3 8.4 6.2e-27 94.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OEU18876.1 - 3.5e-06 26.6 0.6 6.1e-05 22.6 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OEU18876.1 - 4e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 OEU18876.1 - 0.0006 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 OEU18876.1 - 0.0013 18.6 0.0 0.26 11.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OEU18876.1 - 0.0013 19.2 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OEU18876.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 OEU18876.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 OEU18876.1 - 0.024 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Fn3-like PF14310.6 OEU18876.1 - 0.028 14.5 0.2 0.068 13.3 0.2 1.7 1 0 0 1 1 1 0 Fibronectin type III-like domain AAA_22 PF13401.6 OEU18876.1 - 0.046 14.0 0.1 0.17 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OEU18876.1 - 0.047 13.4 0.1 0.047 13.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 OEU18876.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 OEU18876.1 - 0.058 13.1 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 OEU18876.1 - 0.068 13.3 0.0 0.22 11.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OEU18876.1 - 0.11 11.7 0.0 3.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 OEU18876.1 - 0.17 12.4 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OEU18877.1 - 6.9e-13 47.6 9.8 0.17 12.1 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU18877.1 - 2.4e-10 40.6 5.9 5.3e-05 23.4 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU18877.1 - 7.2e-10 38.3 0.5 0.39 10.6 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OEU18877.1 - 4.2e-09 36.9 17.1 0.021 15.5 1.2 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU18877.1 - 1.4e-08 34.2 0.0 1.7 8.4 0.0 6.6 6 0 0 6 6 6 3 TPR repeat TPR_7 PF13176.6 OEU18877.1 - 4.2e-07 29.5 7.0 0.77 9.9 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU18877.1 - 4.5e-07 29.6 8.2 3 8.3 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OEU18877.1 - 4.4e-06 26.7 4.2 3.2 8.3 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU18877.1 - 9.5e-06 26.0 11.7 0.13 12.8 0.1 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU18877.1 - 4e-05 24.1 18.2 0.056 14.3 0.3 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU18877.1 - 0.0038 17.3 4.6 31 4.8 0.1 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU18877.1 - 0.047 13.0 1.5 6.1 6.1 0.1 3.3 3 0 0 3 3 3 0 MalT-like TPR region tRNA_synthFbeta PF17759.1 OEU18877.1 - 0.12 11.8 0.4 0.77 9.2 0.3 2.2 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain TPR_6 PF13174.6 OEU18877.1 - 0.17 12.6 9.1 20 6.1 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU18877.1 - 0.83 9.6 4.3 30 4.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Mgm101p PF06420.12 OEU18878.1 - 0.066 12.7 0.0 0.075 12.6 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 PHD_2 PF13831.6 OEU18879.1 - 4.4 7.0 26.9 2.9 7.5 2.9 3.7 3 0 0 3 3 3 0 PHD-finger Cyclin_N PF00134.23 OEU18880.1 - 2.3e-20 72.7 0.0 9.9e-20 70.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU18880.1 - 4.9e-13 49.2 0.0 9.8e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain PHD PF00628.29 OEU18881.1 - 2.9e-11 43.1 7.6 4.4e-11 42.5 7.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OEU18881.1 - 2.6e-06 26.8 1.4 2.6e-06 26.8 1.4 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 OEU18881.1 - 1.5e-05 25.1 3.5 8.1e-05 22.8 0.9 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OEU18881.1 - 0.00027 21.1 6.8 0.0018 18.5 6.7 2.0 1 1 1 2 2 2 1 PHD-like zinc-binding domain C1_2 PF03107.16 OEU18881.1 - 0.0074 16.6 7.5 0.098 13.0 4.1 2.2 2 0 0 2 2 2 1 C1 domain zf-rbx1 PF12678.7 OEU18881.1 - 0.04 14.2 6.6 0.072 13.4 6.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 OEU18881.1 - 0.059 13.3 3.5 0.059 13.3 3.5 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 OEU18881.1 - 0.083 13.2 8.5 0.19 12.1 8.5 1.7 1 1 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.16 OEU18881.1 - 0.13 12.5 2.3 0.18 12.0 2.3 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Pellino PF04710.14 OEU18881.1 - 0.16 10.6 0.3 0.18 10.5 0.3 1.1 1 0 0 1 1 1 0 Pellino zf-PHD-like PF15446.6 OEU18881.1 - 0.33 10.5 3.6 0.17 11.5 1.3 1.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain ADK_lid PF05191.14 OEU18881.1 - 0.56 10.2 5.9 0.13 12.2 2.3 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid ZapB PF06005.12 OEU18882.1 - 0.0073 16.7 10.5 0.0073 16.7 10.5 2.8 3 0 0 3 3 3 1 Cell division protein ZapB Pro_isomerase PF00160.21 OEU18883.1 - 1.3e-18 67.8 0.2 1.5e-18 67.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MRG PF05712.13 OEU18884.1 - 3.7e-06 26.4 0.0 9.4e-06 25.1 0.0 1.8 1 0 0 1 1 1 1 MRG IIGP PF05049.13 OEU18884.1 - 0.028 13.5 0.0 0.063 12.3 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) S1 PF00575.23 OEU18885.1 - 1.3e-07 31.9 0.5 3.7e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Planc_extracel PF07595.12 OEU18885.1 - 0.62 10.0 0.1 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 Planctomycete extracellular JmjC PF02373.22 OEU18886.1 - 1.6e-38 131.6 0.0 4.1e-38 130.3 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase FMO-like PF00743.19 OEU18887.1 - 2.3e-35 122.1 0.0 4.4e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OEU18887.1 - 9.7e-19 67.7 0.0 1.1e-15 57.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU18887.1 - 1.1e-14 54.4 0.5 3.4e-11 43.0 0.1 3.6 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU18887.1 - 9.2e-13 48.0 1.0 7.8e-09 35.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Phosphonate-bd PF12974.7 OEU18887.1 - 3.4e-09 36.7 0.0 8.7e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Pyr_redox PF00070.27 OEU18887.1 - 7.8e-07 29.6 2.6 0.014 15.9 0.0 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU18887.1 - 8.2e-06 26.0 0.3 8e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU18887.1 - 9.9e-06 25.4 1.5 0.12 12.0 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OEU18887.1 - 1.2e-05 25.4 0.0 0.71 9.9 0.0 3.3 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OEU18887.1 - 0.0016 18.9 0.0 0.33 11.4 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OEU18887.1 - 0.0044 16.3 3.0 0.01 15.2 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OEU18887.1 - 0.021 14.8 0.2 0.13 12.3 0.1 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OEU18887.1 - 0.021 14.2 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M17_N PF02789.17 OEU18887.1 - 0.03 14.2 0.3 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF4147 PF13660.6 OEU18887.1 - 0.061 12.9 0.0 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) 3HCDH_N PF02737.18 OEU18887.1 - 0.2 11.5 0.1 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PfkB PF00294.24 OEU18888.1 - 0.019 14.3 0.7 0.033 13.5 0.7 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DUF393 PF04134.12 OEU18889.1 - 3.2e-23 83.2 0.0 4.2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 GIT1_C PF12205.8 OEU18890.1 - 0.2 11.8 2.1 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term GpcrRhopsn4 PF10192.9 OEU18891.1 - 5.1e-34 117.9 11.0 5.1e-34 117.9 11.0 1.9 2 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 OEU18891.1 - 0.0011 18.2 1.0 0.0011 18.2 1.0 1.8 2 0 0 2 2 2 1 Lung seven transmembrane receptor MFS_3 PF05977.13 OEU18891.1 - 0.0016 16.9 0.5 0.0037 15.7 0.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Lipase_bact_N PF12262.8 OEU18891.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal OppC_N PF12911.7 OEU18891.1 - 3.5 7.7 4.8 65 3.6 0.1 3.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.25 OEU18892.1 - 2.1e-27 95.8 0.0 4.3e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU18892.1 - 9e-22 77.8 0.0 1.1e-19 70.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU18892.1 - 2.5e-09 37.3 0.0 3.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU18892.1 - 0.0084 15.6 0.0 0.023 14.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OEU18892.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pro_isomerase PF00160.21 OEU18893.1 - 1.7e-45 155.1 0.0 3e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OEU18893.1 - 5.4e-07 30.2 0.3 5.4 8.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU18893.1 - 0.0013 19.0 0.0 0.089 13.1 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU18893.1 - 0.029 13.3 0.3 5 6.0 0.0 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mcl1_mid PF12341.8 OEU18893.1 - 0.055 12.8 0.2 8.1 5.7 0.0 2.6 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region ubiquitin PF00240.23 OEU18894.1 - 2.7e-24 84.7 0.3 3e-24 84.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OEU18894.1 - 8.3e-13 48.0 0.3 9.3e-13 47.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OEU18894.1 - 2.6e-05 24.5 0.2 2.9e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 OEU18894.1 - 0.00016 22.1 0.1 0.00058 20.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU18894.1 - 0.00023 21.2 0.1 0.00036 20.6 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OEU18894.1 - 0.014 15.9 0.0 0.017 15.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Dynamin_N PF00350.23 OEU18895.1 - 1.4e-11 44.8 0.0 6.2e-06 26.4 0.0 2.4 1 1 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 OEU18895.1 - 1.2e-06 28.6 0.0 4e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OEU18895.1 - 0.0067 16.8 0.2 0.39 11.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 OEU18895.1 - 0.027 14.7 0.1 2.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF3007 PF11460.8 OEU18895.1 - 0.067 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) FeoB_N PF02421.18 OEU18895.1 - 0.11 12.1 0.1 13 5.3 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OEU18895.1 - 0.13 12.2 0.0 10 6.0 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase SatRNA_48 PF17485.2 OEU18896.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein PET117 PF15786.5 OEU18897.1 - 0.57 10.5 0.0 0.57 10.5 0.0 3.3 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial TIC20 PF16166.5 OEU18898.1 - 3.5e-18 66.0 0.0 4.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like LMBR1 PF04791.16 OEU18900.1 - 1.1e-56 192.8 27.5 9.4e-54 183.2 27.5 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein Acyltransferase PF01553.21 OEU18901.1 - 6e-10 38.9 0.0 7.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Aldo_ket_red PF00248.21 OEU18902.1 - 9.9e-13 47.9 0.1 1.4e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HSDR_N PF04313.14 OEU18902.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) CCB1 PF12046.8 OEU18903.1 - 1.4e-52 177.4 0.0 1.8e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B ACR_tran PF00873.19 OEU18903.1 - 0.21 9.2 0.0 0.28 8.8 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PI3_PI4_kinase PF00454.27 OEU18904.1 - 2e-30 106.4 0.7 2.6e-27 96.2 0.1 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OEU18904.1 - 0.045 13.1 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) NmrA PF05368.13 OEU18905.1 - 3.6e-12 46.3 0.1 5.6e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OEU18905.1 - 1.2e-05 25.3 0.1 1.8e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DUF727 PF05303.12 OEU18905.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF727) EamA PF00892.20 OEU18906.1 - 1.5e-18 67.3 30.2 1.4e-09 38.3 13.8 3.8 3 2 0 3 3 3 3 EamA-like transporter family Pex24p PF06398.11 OEU18906.1 - 0.52 9.3 7.8 0.06 12.3 0.5 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin adh_short PF00106.25 OEU18907.1 - 7.5e-23 81.0 0.0 3.6e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU18907.1 - 6.8e-16 58.5 0.0 1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU18907.1 - 6e-06 26.3 0.0 9.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OEU18907.1 - 0.0045 16.4 0.0 0.0052 16.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU18907.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5407 PF17401.2 OEU18907.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5407) Glyoxalase PF00903.25 OEU18908.1 - 2.7e-05 24.3 0.0 0.0066 16.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2102 PF09875.9 OEU18908.1 - 0.0058 16.3 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2102) FA_desaturase PF00487.24 OEU18909.1 - 1.3e-22 80.9 7.9 5.7e-22 78.8 7.9 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Chloroa_b-bind PF00504.21 OEU18910.1 - 0.04 14.4 0.0 0.04 14.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyll A-B binding protein ELMO_CED12 PF04727.13 OEU18911.1 - 7.4e-14 52.2 0.0 1.5e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family AbiH PF14253.6 OEU18912.1 - 0.081 12.8 11.6 0.13 12.1 11.6 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Cytokin_check_N PF10407.9 OEU18912.1 - 0.23 11.5 4.8 0.51 10.3 1.0 3.0 2 1 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Maelstrom PF13017.6 OEU18912.1 - 0.67 9.6 6.5 1.1 8.9 6.5 1.3 1 0 0 1 1 1 0 piRNA pathway germ-plasm component Atg14 PF10186.9 OEU18912.1 - 1.3 8.0 19.8 2.3 7.2 19.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 OEU18912.1 - 1.4 8.7 28.2 1.8 8.4 26.8 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OEU18912.1 - 1.9 8.5 28.2 8.6 6.4 10.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNase_J_C PF17770.1 OEU18912.1 - 4.5 8.4 12.0 0.91 10.6 0.8 3.1 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain Fez1 PF06818.15 OEU18912.1 - 5.2 7.5 28.7 0.082 13.4 4.0 2.7 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 OEU18912.1 - 5.6 7.6 28.4 0.25 12.0 12.9 3.3 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 OEU18912.1 - 5.7 4.7 19.7 4.4 5.1 18.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 OEU18912.1 - 7.6 6.9 6.3 5.9 7.2 3.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF5595 PF18077.1 OEU18912.1 - 8.6 6.5 11.3 2.9 8.0 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) PNTB PF02233.16 OEU18913.1 - 8.6e-167 555.7 22.4 8.6e-167 555.7 22.4 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OEU18913.1 - 5.7e-70 234.9 0.8 5.7e-70 234.9 0.8 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OEU18913.1 - 6.3e-43 146.3 0.0 1.6e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OEU18913.1 - 3.5e-26 91.5 7.2 3.5e-26 91.5 7.2 3.5 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 OEU18913.1 - 2.2e-06 27.1 0.6 0.045 13.1 0.0 4.4 5 0 0 5 5 5 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OEU18913.1 - 0.022 14.7 0.2 0.18 11.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF1826 PF08856.11 OEU18914.1 - 1.7e-10 41.2 0.0 3.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) MRC1 PF09444.10 OEU18914.1 - 0.32 11.5 4.5 0.97 9.9 1.2 2.4 2 0 0 2 2 2 0 MRC1-like domain FAD_binding_2 PF00890.24 OEU18915.1 - 1.1e-67 228.9 2.9 1.5e-67 228.5 2.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU18915.1 - 8.9e-06 25.1 0.4 0.038 13.2 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU18915.1 - 1e-05 25.3 0.9 4.2e-05 23.3 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Succ_DH_flav_C PF02910.20 OEU18915.1 - 0.00034 20.6 0.1 0.0015 18.5 0.1 2.0 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 OEU18915.1 - 0.033 13.3 0.8 0.66 9.0 0.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OEU18915.1 - 0.076 13.3 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_7 PF03441.14 OEU18916.1 - 2.3e-41 141.5 2.4 4.1e-41 140.7 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OEU18916.1 - 2.1e-10 40.9 0.0 4.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase RTC PF01137.21 OEU18916.1 - 0.066 12.4 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase TSGP1 PF07771.11 OEU18916.1 - 0.58 10.3 3.4 0.29 11.3 0.7 1.9 2 0 0 2 2 2 0 Tick salivary peptide group 1 PT PF04886.12 OEU18917.1 - 4.1e-12 45.4 102.1 1.8e+04 -52.6 102.1 5.3 1 1 0 1 1 1 0 PT repeat UPF0231 PF06062.11 OEU18917.1 - 0.012 15.9 2.2 1.3 9.3 1.3 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Asp_protease PF09668.10 OEU18921.1 - 0.00058 19.7 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Pkinase PF00069.25 OEU18923.1 - 6e-52 176.6 0.1 7.9e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU18923.1 - 4.8e-31 108.0 0.0 7e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU18923.1 - 2.7e-06 26.9 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OEU18923.1 - 2.5e-05 23.4 0.6 3.3e-05 23.0 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OEU18923.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU18923.1 - 0.0092 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OEU18923.1 - 0.042 13.5 0.7 2.7 7.6 0.4 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OEU18923.1 - 0.05 12.9 0.1 0.085 12.2 0.1 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-B_dimeris PF09026.10 OEU18923.1 - 0.64 10.4 8.1 0.46 10.9 5.1 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain S_100 PF01023.19 OEU18924.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Ank_2 PF12796.7 OEU18925.1 - 4e-18 65.8 0.0 2.3e-07 31.3 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU18925.1 - 4.1e-17 62.0 2.7 1.9e-05 24.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU18925.1 - 3.8e-11 42.9 0.7 0.27 11.8 0.0 6.0 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OEU18925.1 - 6.6e-11 42.5 1.6 0.00079 19.9 0.0 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU18925.1 - 1.6e-10 40.3 1.0 0.15 12.7 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ion_trans PF00520.31 OEU18925.1 - 3.8e-07 29.6 19.4 3.8e-07 29.6 19.4 1.8 3 0 0 3 3 3 1 Ion transport protein PKD_channel PF08016.12 OEU18925.1 - 0.036 12.7 12.8 0.055 12.1 1.5 2.4 2 0 0 2 2 2 0 Polycystin cation channel ELO PF01151.18 OEU18929.1 - 1.5e-66 224.5 20.1 1.8e-66 224.2 20.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pox_A14 PF05767.12 OEU18929.1 - 0.018 15.2 1.3 0.018 15.2 1.3 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3439 PF11921.8 OEU18930.1 - 0.27 11.2 1.7 1.8 8.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LMBR1 PF04791.16 OEU18930.1 - 5 5.9 6.8 6.9 5.5 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3575 PF12099.8 OEU18931.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) ELO PF01151.18 OEU18932.1 - 5.5e-68 229.2 22.1 6.9e-68 228.9 22.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PH PF00169.29 OEU18933.1 - 6.3e-08 33.1 0.1 0.015 15.8 0.1 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OEU18933.1 - 0.18 12.2 0.1 0.18 12.2 0.1 3.7 4 0 0 4 4 4 0 Pleckstrin homology domain DUF5595 PF18077.1 OEU18933.1 - 0.74 9.9 8.6 7 6.8 3.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Hydrolase_4 PF12146.8 OEU18934.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SR-25 PF10500.9 OEU18934.1 - 1.1 8.8 12.6 0.86 9.2 10.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Adenylsucc_synt PF00709.21 OEU18935.1 - 4.6e-173 575.9 0.0 5.3e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Chloroa_b-bind PF00504.21 OEU18936.1 - 8.5e-41 140.2 0.6 1.1e-40 139.8 0.6 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Calici_coat_C PF08435.11 OEU18936.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal URO-D PF01208.17 OEU18937.1 - 5.9e-110 367.7 0.0 7.2e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FmiP_Thoc5 PF09766.9 OEU18938.1 - 1.2e-08 34.7 0.0 0.0034 16.7 0.0 2.2 2 0 0 2 2 2 2 Fms-interacting protein/Thoc5 Mpv17_PMP22 PF04117.12 OEU18939.1 - 1.3e-14 54.1 0.0 2.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family NrfD PF03916.14 OEU18939.1 - 0.038 13.6 2.6 0.054 13.1 2.6 1.2 1 0 0 1 1 1 0 Polysulphide reductase, NrfD DUF4381 PF14316.6 OEU18939.1 - 0.085 13.1 0.5 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FAD_binding_6 PF00970.24 OEU18940.1 - 2.6e-30 104.7 0.0 4e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OEU18940.1 - 1.2e-29 103.1 0.0 1.9e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OEU18940.1 - 0.0001 22.5 0.0 0.0065 16.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Phage_TAC_6 PF09550.10 OEU18940.1 - 0.0062 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC FAD_binding_9 PF08021.11 OEU18940.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain WD40 PF00400.32 OEU18941.1 - 2.9e-12 46.9 9.9 7.3e-06 26.6 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU18941.1 - 3.9e-05 23.9 0.0 0.89 9.9 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OEU18941.1 - 0.032 13.6 0.2 0.33 10.3 0.1 2.1 1 1 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 OEU18941.1 - 0.061 13.8 1.3 49 4.6 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain Beach PF02138.18 OEU18942.1 - 3.4e-122 407.1 0.1 4.1e-122 406.9 0.1 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OEU18942.1 - 7.1e-17 61.4 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Aldo_ket_red PF00248.21 OEU18943.1 - 1.7e-22 80.0 0.0 4.8e-21 75.2 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4201 PF13870.6 OEU18943.1 - 0.013 15.3 0.5 0.022 14.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Scramblase PF03803.15 OEU18944.1 - 1.8e-18 66.7 0.1 1.9e-08 33.9 1.5 2.1 2 0 0 2 2 2 2 Scramblase Orf78 PF06024.12 OEU18945.1 - 0.15 12.3 1.7 0.21 11.9 0.4 1.9 2 1 0 2 2 2 0 Orf78 (ac78) Arf PF00025.21 OEU18946.1 - 4.6e-63 211.8 0.0 5.2e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OEU18946.1 - 1.3e-09 37.7 0.3 6.1e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OEU18946.1 - 3.1e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OEU18946.1 - 4.1e-08 33.5 0.0 9.2e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OEU18946.1 - 4.3e-08 32.9 0.0 5.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OEU18946.1 - 7.7e-07 29.2 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OEU18946.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OEU18946.1 - 0.0046 16.5 0.1 0.15 11.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Antibiotic_NAT PF02522.14 OEU18946.1 - 0.035 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase cobW PF02492.19 OEU18946.1 - 0.052 13.1 0.0 5.3 6.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OEU18946.1 - 0.054 13.4 0.0 7.3 6.5 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OEU18946.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 OEU18946.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Peptidase_C54 PF03416.19 OEU18947.1 - 2.2e-76 256.9 0.0 3.1e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 OEU18947.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C78 CAF1 PF04857.20 OEU18948.1 - 3.1e-68 230.3 0.0 4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 OEU18948.1 - 0.14 11.8 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 3'-5' exonuclease UPF0172 PF03665.13 OEU18949.1 - 1e-23 84.4 0.1 1.2e-23 84.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 OEU18949.1 - 2.9e-07 30.5 0.0 5.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RRM_1 PF00076.22 OEU18950.1 - 2.6e-07 30.3 0.1 5.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OEU18950.1 - 8.4e-05 22.6 0.1 0.00018 21.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif TMEM51 PF15345.6 OEU18950.1 - 0.0026 17.7 0.1 0.0069 16.3 0.1 1.7 1 0 0 1 1 1 1 Transmembrane protein 51 Limkain-b1 PF11608.8 OEU18950.1 - 0.0065 16.5 0.4 0.015 15.3 0.4 1.6 1 0 0 1 1 1 1 Limkain b1 ETRAMP PF09716.10 OEU18950.1 - 0.095 12.8 9.8 0.0065 16.5 4.4 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Insulin_TMD PF17870.1 OEU18950.1 - 0.1 12.6 1.1 0.27 11.3 1.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SCIMP PF15050.6 OEU18950.1 - 0.11 13.0 0.1 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 SCIMP protein TMEM154 PF15102.6 OEU18950.1 - 1.9 8.4 6.5 0.12 12.3 0.7 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF5403 PF17395.2 OEU18951.1 - 0.027 14.7 1.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Spore_III_AB PF09548.10 OEU18951.1 - 0.19 11.9 0.0 0.44 10.6 0.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RVT_2 PF07727.14 OEU18953.1 - 0.0035 17.0 0.1 0.0039 16.9 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NUC173 PF08161.12 OEU18954.1 - 1.1e-26 93.7 0.1 1.5e-24 86.9 0.0 2.9 2 0 0 2 2 2 1 NUC173 domain Ovate PF04844.13 OEU18954.1 - 0.022 14.7 1.4 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 Transcriptional repressor, ovate PBP1_TM PF14812.6 OEU18954.1 - 0.25 11.7 6.7 1.2 9.5 6.7 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UNC45-central PF11701.8 OEU18954.1 - 1.6 8.7 5.4 2.3 8.1 0.0 3.8 4 2 0 4 4 4 0 Myosin-binding striated muscle assembly central Aa_trans PF01490.18 OEU18955.1 - 2e-52 178.3 4.2 8.2e-52 176.3 4.2 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU18955.1 - 1.6e-13 50.5 19.2 1.7e-12 47.1 11.0 3.4 3 0 0 3 3 3 3 Tryptophan/tyrosine permease family GhoS PF11080.8 OEU18956.1 - 0.00073 19.5 11.9 14 5.7 0.0 5.9 6 0 0 6 6 6 1 Endoribonuclease GhoS CBM77 PF18283.1 OEU18956.1 - 0.0026 18.1 9.0 1.1e+02 3.2 0.1 6.3 4 2 1 6 6 6 0 Carbohydrate binding module 77 NMT1 PF09084.11 OEU18956.1 - 0.011 15.7 0.1 44 3.9 0.0 3.5 3 0 0 3 3 3 0 NMT1/THI5 like EPSP_synthase PF00275.20 OEU18956.1 - 0.037 12.7 0.0 34 3.0 0.0 3.4 3 0 0 3 3 3 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) OAS1_C PF10421.9 OEU18956.1 - 0.7 9.4 3.2 28 4.1 0.0 4.4 6 0 0 6 6 6 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Cadherin_4 PF17803.1 OEU18956.1 - 1.4 9.6 51.9 1.9 9.2 0.9 6.9 7 0 0 7 7 7 0 Bacterial cadherin-like domain Chon_Sulph_att PF06566.11 OEU18956.1 - 1.6 8.6 22.3 15 5.3 0.2 5.8 3 3 2 6 6 6 0 Chondroitin sulphate attachment domain C1_1 PF00130.22 OEU18956.1 - 2.6 8.0 38.9 11 6.0 0.4 7.1 7 0 0 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LSM PF01423.22 OEU18957.1 - 2.4e-06 27.2 1.4 6.1e-06 25.8 1.4 1.7 1 1 0 1 1 1 1 LSM domain Sulfotransfer_3 PF13469.6 OEU18958.1 - 5.3e-37 128.3 0.0 1.6e-36 126.7 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OEU18958.1 - 7.5e-13 48.6 0.0 1.7e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain TPR_1 PF00515.28 OEU18958.1 - 1.2e-06 28.1 0.3 0.00011 21.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU18958.1 - 0.00016 21.5 0.1 0.013 15.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU18958.1 - 0.0019 17.8 0.7 0.35 10.6 0.0 3.0 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 OEU18958.1 - 0.0094 16.1 2.0 0.89 9.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU18958.1 - 0.08 13.2 0.0 0.73 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Rhomboid PF01694.22 OEU18959.1 - 4.3e-33 114.4 10.8 4.3e-33 114.4 10.8 1.8 3 0 0 3 3 3 1 Rhomboid family Mito_carr PF00153.27 OEU18960.1 - 5e-64 212.3 4.3 4.8e-22 77.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 OEU18960.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Trep_Strep PF09605.10 OEU18960.1 - 0.13 12.2 0.9 0.55 10.2 0.3 2.0 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) EMG1 PF03587.14 OEU18962.1 - 1.6e-68 230.2 0.0 1.9e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Mito_carr PF00153.27 OEU18963.1 - 1.8e-55 184.9 5.1 1.5e-20 72.9 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein PEX11 PF05648.14 OEU18963.1 - 0.14 11.6 0.3 0.65 9.4 0.3 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Tropomyosin_1 PF12718.7 OEU18964.1 - 0.0065 16.6 9.2 0.0065 16.6 9.2 10.2 6 3 3 10 10 10 1 Tropomyosin like CENP-F_leu_zip PF10473.9 OEU18964.1 - 0.0074 16.3 10.4 0.0074 16.3 10.4 11.0 4 4 5 11 11 11 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ras PF00071.22 OEU18965.1 - 1.1e-38 132.3 0.0 1.3e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU18965.1 - 4.1e-10 39.9 0.0 5.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OEU18965.1 - 2.4e-06 27.6 0.0 9.7e-06 25.7 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU18965.1 - 6e-06 26.3 0.0 0.006 16.5 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 OEU18965.1 - 0.00021 20.8 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OEU18965.1 - 0.001 18.6 0.0 0.012 15.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OEU18965.1 - 0.033 13.7 0.1 0.41 10.2 0.1 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ser_hydrolase PF06821.13 OEU18965.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase TPR_1 PF00515.28 OEU18966.1 - 1.4e-17 62.7 1.1 0.004 16.9 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU18966.1 - 2.3e-17 61.6 0.0 0.00032 20.6 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU18966.1 - 1.5e-13 49.7 0.3 0.015 15.5 0.7 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU18966.1 - 8.5e-13 47.8 0.1 0.00017 21.2 0.0 4.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 OEU18966.1 - 2.2e-11 43.6 0.1 0.017 15.9 0.0 5.9 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU18966.1 - 4.9e-10 38.7 0.2 0.3 11.2 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU18966.1 - 7.9e-10 38.9 0.7 0.67 10.3 0.0 5.8 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OEU18966.1 - 2.8e-09 37.5 0.0 0.00084 19.9 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU18966.1 - 4.2e-08 33.0 0.2 0.13 12.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU18966.1 - 8.9e-07 29.1 0.0 0.0042 17.3 0.1 3.5 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OEU18966.1 - 0.00019 21.9 0.1 0.071 13.6 0.0 3.5 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU18966.1 - 0.0014 19.1 1.2 0.12 13.1 0.0 4.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 OEU18966.1 - 0.003 17.0 0.1 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 Coatomer epsilon subunit RPN7 PF10602.9 OEU18966.1 - 0.0041 16.9 0.1 0.11 12.2 0.0 2.8 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 OEU18966.1 - 0.015 15.4 0.0 0.14 12.4 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Clathrin PF00637.20 OEU18966.1 - 0.022 14.6 0.7 0.3 10.9 0.0 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS AsnC_trans_reg PF01037.21 OEU18966.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Pterin_4a PF01329.19 OEU18967.1 - 6.4e-21 74.3 0.1 8.1e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase TPM_phosphatase PF04536.14 OEU18968.1 - 1.6e-11 44.5 0.0 1.9e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 TPM domain OprF PF05736.11 OEU18968.1 - 0.04 13.7 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 OprF membrane domain Strep_SA_rep PF06696.11 OEU18969.1 - 0.0078 16.2 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Streptococcal surface antigen repeat TsaE PF02367.17 OEU18970.1 - 3e-20 72.5 0.2 2.2e-10 40.6 0.1 2.9 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NDK PF00334.19 OEU18971.1 - 0.00074 19.5 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Nucleoside diphosphate kinase GXWXG PF14231.6 OEU18971.1 - 0.15 12.1 0.2 2.9 8.0 0.0 2.7 2 1 1 3 3 3 0 GXWXG protein Acetyltransf_1 PF00583.25 OEU18972.1 - 8.6e-10 38.9 0.1 1.7e-09 37.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU18972.1 - 1.4e-06 28.3 0.0 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU18972.1 - 0.00012 21.9 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OEU18972.1 - 0.00022 21.6 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_33 PF10017.9 OEU18973.1 - 0.046 12.9 0.2 0.048 12.8 0.2 1.0 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent ADK PF00406.22 OEU18974.1 - 7e-32 110.6 0.0 1.7e-31 109.3 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU18974.1 - 6.6e-25 88.1 0.0 8.5e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU18974.1 - 0.00011 22.7 0.0 0.00027 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU18974.1 - 0.00034 20.8 0.0 0.004 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OEU18974.1 - 0.015 15.6 0.0 0.02 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 OEU18974.1 - 0.044 13.5 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.27 OEU18974.1 - 0.17 12.4 0.0 0.21 12.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter HSF_DNA-bind PF00447.17 OEU18976.1 - 4.7e-13 49.6 0.0 5.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Cpn10 PF00166.21 OEU18977.1 - 1.3e-35 121.3 0.0 7.8e-17 61.1 0.1 2.2 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit Glycoprotein PF03409.15 OEU18977.1 - 1.2 7.9 7.9 1.7 7.4 7.9 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Abhydrolase_1 PF00561.20 OEU18979.1 - 4.1e-28 98.7 0.0 5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU18979.1 - 0.012 15.0 0.1 0.045 13.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ala_racemase_N PF01168.20 OEU18981.1 - 2.7e-20 72.9 0.0 3.3e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Chloroa_b-bind PF00504.21 OEU18983.1 - 3.1e-33 115.6 0.2 4.1e-33 115.2 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Peptidase_M41 PF01434.18 OEU18984.1 - 0.0015 18.4 1.3 0.025 14.4 0.1 2.9 2 1 0 2 2 2 1 Peptidase family M41 LRRNT_2 PF08263.12 OEU18984.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain PAN_4 PF14295.6 OEU18985.1 - 1.8e-05 24.6 9.0 0.003 17.5 0.9 2.9 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 OEU18985.1 - 0.00013 22.0 21.3 0.00035 20.6 0.7 3.8 3 0 0 3 3 3 2 PAN-like domain PAN_1 PF00024.26 OEU18985.1 - 0.0026 17.7 15.9 0.021 14.8 0.6 3.3 3 0 0 3 3 3 2 PAN domain Kringle PF00051.18 OEU18986.1 - 0.0027 18.0 2.8 0.014 15.7 2.8 2.2 1 1 0 1 1 1 1 Kringle domain Afaf PF15339.6 OEU18986.1 - 0.019 14.7 1.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 0 Acrosome formation-associated factor DnaJ PF00226.31 OEU18987.1 - 1.2e-21 76.5 2.2 1.5e-21 76.3 2.2 1.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OEU18987.1 - 0.00065 19.6 0.1 0.0054 16.6 0.0 2.0 2 0 0 2 2 2 1 A repeated domain in UCH-protein AbiH PF14253.6 OEU18988.1 - 0.12 12.2 1.2 0.31 10.9 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH NKWYS PF10364.9 OEU18988.1 - 0.84 9.8 3.9 0.63 10.2 0.1 2.6 3 0 0 3 3 3 0 Putative capsular polysaccharide synthesis protein NPF PF16601.5 OEU18990.1 - 8.5 6.8 7.7 12 6.4 5.9 2.1 1 1 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif GLE1 PF07817.13 OEU18992.1 - 0.19 10.9 6.4 0.38 9.9 0.6 2.5 1 1 0 2 2 2 0 GLE1-like protein DUF745 PF05335.13 OEU18992.1 - 0.45 10.2 14.0 0.19 11.4 9.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) MukF_M PF17192.4 OEU18992.1 - 0.92 9.2 7.1 0.77 9.5 1.7 2.6 2 1 0 2 2 2 0 MukF middle domain CorA PF01544.18 OEU18992.1 - 1.6 8.0 6.9 0.63 9.3 0.8 2.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Golgin_A5 PF09787.9 OEU18992.1 - 1.8 8.0 17.5 0.034 13.6 9.5 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 OEU18992.1 - 1.9 8.6 6.9 19 5.3 0.4 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OEU18992.1 - 4.8 7.5 9.4 7.2 7.0 1.3 2.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 OEU18992.1 - 7.2 7.1 10.4 1.6 9.2 0.9 3.6 1 1 1 2 2 2 0 Cell division protein ZapB KxDL PF10241.9 OEU18992.1 - 9.5 6.6 9.4 1.1 9.6 0.6 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein UL42 PF17638.2 OEU18993.1 - 0.66 10.0 7.9 2 8.4 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 DUF4658 PF15555.6 OEU18994.1 - 0.14 12.3 2.1 1 9.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) PPI_Ypi1 PF07491.11 OEU18994.1 - 2.4 8.1 6.5 7.2 6.5 0.0 3.3 4 0 0 4 4 4 0 Protein phosphatase inhibitor Myotub-related PF06602.14 OEU18995.1 - 1.3e-109 366.4 0.1 1.5e-109 366.2 0.1 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 OEU18995.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PT PF04886.12 OEU18996.1 - 0.00072 19.0 37.8 1.2 8.7 13.5 4.1 1 1 1 2 2 2 1 PT repeat Lactonase PF10282.9 OEU18996.1 - 0.0012 18.2 0.1 0.0076 15.6 0.0 2.1 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 OEU18996.1 - 0.014 15.7 0.1 2.9 8.2 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FG-GAP_2 PF14312.6 OEU18996.1 - 0.03 14.5 3.1 4.4 7.6 0.1 3.7 4 0 0 4 4 4 0 FG-GAP repeat Ribosomal_L20 PF00453.18 OEU18997.1 - 1e-31 109.2 2.9 1.3e-31 108.8 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Thioredoxin PF00085.20 OEU18998.1 - 6.3e-22 77.5 0.7 1.1e-21 76.8 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU18998.1 - 5.9e-06 26.7 0.7 7e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU18998.1 - 0.00058 20.1 0.4 0.0048 17.2 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU18998.1 - 0.00097 19.1 0.4 0.0027 17.6 0.1 2.1 1 1 1 2 2 2 1 AhpC/TSA family ZnuA PF01297.17 OEU18998.1 - 0.0033 16.9 0.4 0.0048 16.3 0.4 1.2 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Redoxin PF08534.10 OEU18998.1 - 0.029 14.1 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Redoxin RasGAP_C PF03836.15 OEU18998.1 - 0.052 13.7 0.4 0.084 13.0 0.4 1.3 1 0 0 1 1 1 0 RasGAP C-terminus gpD PF02925.16 OEU18998.1 - 0.067 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D ParB PF08775.10 OEU18998.1 - 0.097 13.2 1.8 0.16 12.4 1.1 1.6 1 1 0 1 1 1 0 ParB family PHM7_cyt PF14703.6 OEU18998.1 - 0.12 12.6 0.8 0.28 11.4 0.7 1.7 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF2999 PF11212.8 OEU18998.1 - 0.13 12.6 0.5 0.22 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Kazal_2 PF07648.15 OEU18998.1 - 0.15 12.3 1.4 0.56 10.4 0.1 2.2 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain CLZ PF16526.5 OEU18998.1 - 0.71 10.3 4.7 0.82 10.1 3.6 1.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHR3_chaperone PF08229.11 OEU18999.1 - 0.064 12.2 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 tRNA-synt_1b PF00579.25 OEU19000.1 - 2e-17 63.4 0.0 3.6e-17 62.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PC-Esterase PF13839.6 OEU19003.1 - 2.3e-09 37.4 3.9 0.0002 21.2 1.0 2.5 1 1 1 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_A22B PF04258.13 OEU19004.1 - 5.6e-50 170.5 5.5 7e-50 170.1 5.5 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PPP4R2 PF09184.11 OEU19005.1 - 6.5 6.2 18.5 8.2 5.9 18.5 1.0 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.7 OEU19005.1 - 6.8 4.7 10.7 7.4 4.6 10.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein COG4 PF08318.12 OEU19006.1 - 5.6e-06 25.7 0.9 3.9e-05 22.9 0.4 2.3 2 0 0 2 2 2 1 COG4 transport protein Peptidase_U49 PF10463.9 OEU19006.1 - 0.13 12.0 1.2 0.29 10.8 0.3 2.0 2 0 0 2 2 2 0 Peptidase U49 DIL PF01843.19 OEU19006.1 - 0.87 9.9 3.9 7.8 6.8 0.6 3.1 2 1 0 2 2 2 0 DIL domain CENP-B_dimeris PF09026.10 OEU19006.1 - 4.8 7.6 7.7 3.2 8.2 0.2 3.4 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Complex1_LYR PF05347.15 OEU19007.1 - 3.5e-11 43.0 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 OEU19007.1 - 0.077 13.6 0.0 0.085 13.5 0.0 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Sulfate_transp PF00916.20 OEU19008.1 - 9.9e-39 133.2 15.7 2.2e-38 132.0 15.7 1.6 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OEU19008.1 - 1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain LPD38 PF18857.1 OEU19009.1 - 0.05 13.7 0.1 8 6.6 0.1 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 Mito_carr PF00153.27 OEU19010.1 - 9.9e-38 128.0 0.4 4.3e-20 71.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 OEU19010.1 - 0.094 12.8 0.2 0.094 12.8 0.2 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit UFD1 PF03152.14 OEU19011.1 - 1.9e-31 108.9 0.0 4.4e-31 107.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Na_H_Exchanger PF00999.21 OEU19013.1 - 2.9e-38 131.7 27.2 4e-38 131.2 27.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_S51 PF03575.17 OEU19014.1 - 2e-05 24.4 0.1 0.013 15.1 0.0 3.3 3 1 1 4 4 4 2 Peptidase family S51 HSF_DNA-bind PF00447.17 OEU19015.1 - 1.5e-07 31.9 16.1 1.6e-06 28.6 14.2 3.3 2 1 0 2 2 2 1 HSF-type DNA-binding ketoacyl-synt PF00109.26 OEU19016.1 - 9.1e-38 130.3 0.3 1.5e-37 129.6 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OEU19016.1 - 2.1e-28 98.7 0.1 5e-28 97.5 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OEU19016.1 - 0.018 15.5 0.0 0.096 13.2 0.0 2.3 3 1 1 4 4 4 0 Ketoacyl-synthetase C-terminal extension TrmK PF04816.12 OEU19016.1 - 0.028 13.9 0.2 2.6 7.5 0.0 2.9 3 0 0 3 3 3 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 OEU19016.1 - 0.14 12.0 0.3 14 5.6 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain Pro_isomerase PF00160.21 OEU19017.1 - 1.8e-12 47.8 0.0 2.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MYND PF01753.18 OEU19018.1 - 8.7e-10 38.5 14.7 1.3e-09 37.9 14.7 1.3 1 0 0 1 1 1 1 MYND finger XH PF03469.14 OEU19018.1 - 0.0053 16.7 0.3 0.0096 15.8 0.3 1.4 1 0 0 1 1 1 1 XH domain BRF1 PF07741.13 OEU19018.1 - 0.1 12.9 1.9 0.18 12.2 1.9 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain zf-C6H2 PF15801.5 OEU19018.1 - 0.38 11.1 10.7 0.79 10.1 10.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Zn_ribbon_17 PF17120.5 OEU19018.1 - 0.41 10.3 7.7 0.67 9.6 7.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Hormone_2 PF00123.20 OEU19021.1 - 0.36 10.8 1.4 2.8 7.9 1.4 2.2 1 1 0 1 1 1 0 Peptide hormone PseudoU_synth_2 PF00849.22 OEU19023.1 - 2.5e-19 69.9 0.2 2.5e-19 69.9 0.2 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase Sulfotransfer_1 PF00685.27 OEU19024.1 - 7.5e-05 22.3 1.5 0.00094 18.7 1.5 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU19024.1 - 0.043 14.2 1.0 8.9 6.6 0.1 2.8 2 1 0 3 3 3 0 Sulfotransferase family Clr2_transil PF16761.5 OEU19024.1 - 0.048 14.5 4.6 0.13 13.1 0.4 3.1 3 0 0 3 3 3 0 Transcription-silencing protein, cryptic loci regulator Clr2 DUF3246 PF11596.8 OEU19025.1 - 0.012 15.1 14.2 0.017 14.6 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NAD_binding_10 PF13460.6 OEU19026.1 - 6.9e-18 65.2 0.0 1.3e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 OEU19026.1 - 3.8e-14 52.8 0.1 3.6e-10 39.8 0.0 3.0 3 0 0 3 3 3 2 NmrA-like family CIA30 PF08547.12 OEU19026.1 - 0.00016 21.7 0.1 0.00042 20.4 0.1 1.6 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) 3Beta_HSD PF01073.19 OEU19026.1 - 0.00017 20.7 0.0 0.00074 18.6 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OEU19026.1 - 0.035 13.6 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 OEU19027.1 - 2.3e-52 174.9 2.2 2.1e-20 72.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SUA5 PF03481.13 OEU19028.1 - 0.31 11.6 7.7 23 5.5 0.0 4.3 1 1 4 5 5 5 0 Putative GTP-binding controlling metal-binding DUF347 PF03988.12 OEU19029.1 - 0.059 13.6 1.7 0.096 12.9 1.7 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) 2OG-FeII_Oxy_3 PF13640.6 OEU19030.1 - 2.4e-13 50.8 0.0 6.4e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.12 OEU19030.1 - 0.0058 16.0 11.8 0.01 15.2 11.8 1.4 1 0 0 1 1 1 1 NOA36 protein RXT2_N PF08595.11 OEU19030.1 - 0.015 15.4 1.8 0.033 14.2 1.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 OEU19030.1 - 0.032 13.4 15.5 0.051 12.7 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 OEU19030.1 - 0.033 14.6 16.6 0.033 14.6 16.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain 2OG-FeII_Oxy_5 PF13759.6 OEU19030.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CDC45 PF02724.14 OEU19030.1 - 0.17 10.2 3.4 0.21 9.8 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 OEU19030.1 - 0.3 10.6 4.5 0.43 10.1 4.5 1.2 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 OEU19030.1 - 0.38 9.2 4.8 0.41 9.1 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 OEU19030.1 - 1.2 8.4 4.4 1.3 8.2 4.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OEU19030.1 - 1.6 6.8 9.7 2 6.5 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 OEU19030.1 - 1.9 8.6 6.8 2.3 8.3 6.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein GCIP PF13324.6 OEU19030.1 - 2.5 7.6 5.8 3.9 7.0 5.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Calpain_inhib PF00748.19 OEU19031.1 - 0.024 15.1 3.5 0.045 14.3 3.5 1.4 1 0 0 1 1 1 0 Calpain inhibitor VTC PF09359.10 OEU19032.1 - 9.7e-71 238.4 0.1 1.4e-70 237.8 0.1 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 OEU19032.1 - 2e-10 40.9 1.1 2e-10 40.9 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 OEU19032.1 - 7.2e-08 32.8 5.2 0.0055 16.7 0.2 3.0 2 1 1 3 3 3 2 SPX domain NrsF PF06532.11 OEU19032.1 - 0.02 14.6 2.1 0.031 14.0 2.1 1.2 1 0 0 1 1 1 0 Negative regulator of sigma F GPS2_interact PF15784.5 OEU19032.1 - 0.11 12.9 0.7 0.24 11.9 0.7 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PRA-CH PF01502.18 OEU19032.1 - 0.51 10.2 2.8 0.45 10.4 0.1 2.4 2 1 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase Glyco_transf_28 PF03033.20 OEU19033.1 - 5e-17 62.2 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OEU19033.1 - 9.2e-06 24.7 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OEU19033.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain HA PF03457.14 OEU19034.1 - 1e-118 387.7 43.6 9e-17 61.2 0.1 9.0 8 1 0 8 8 8 8 Helicase associated domain CSRNP_N PF16019.5 OEU19034.1 - 0.082 12.8 0.1 0.082 12.8 0.1 3.0 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus AGTRAP PF06396.11 OEU19034.1 - 0.099 12.4 0.4 31 4.3 0.0 4.0 5 0 0 5 5 5 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF4828 PF16110.5 OEU19034.1 - 0.72 10.4 9.4 16 6.0 0.4 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4828) Aa_trans PF01490.18 OEU19035.1 - 1.1e-46 159.4 19.8 1.3e-46 159.2 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU19035.1 - 1.1e-07 31.3 8.0 1.1e-07 31.3 8.0 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family SMAP PF15477.6 OEU19036.1 - 8.2 7.5 8.1 1.3 10.0 2.5 2.7 2 0 0 2 2 2 0 Small acidic protein family MMgT PF10270.9 OEU19037.1 - 9.5e-11 41.9 0.1 1.7e-10 41.1 0.1 1.4 1 1 0 1 1 1 1 Membrane magnesium transporter ELP6 PF09807.9 OEU19037.1 - 0.071 12.5 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation complex protein 6 HAD_2 PF13419.6 OEU19038.1 - 3e-12 47.0 1.6 6.1e-12 46.0 1.6 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU19038.1 - 1.8e-09 38.2 0.0 1.6e-07 31.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU19038.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OEU19038.1 - 0.0066 16.9 0.0 0.5 10.7 0.1 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OEU19038.1 - 0.015 15.1 0.5 1.5 8.7 0.5 2.2 1 1 0 1 1 1 0 Acid Phosphatase Methyltransf_7 PF03492.15 OEU19039.1 - 1e-28 100.6 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase ELFV_dehydrog PF00208.21 OEU19040.1 - 4.8e-14 52.7 0.5 6.1e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OEU19040.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ThiF PF00899.21 OEU19040.1 - 0.0084 15.5 0.2 0.019 14.4 0.1 1.6 1 1 1 2 2 2 1 ThiF family 2-Hacid_dh_C PF02826.19 OEU19040.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 OEU19041.1 - 5.1e-29 102.0 0.0 5.9e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OEU19041.1 - 6.5e-06 25.7 0.2 1.8e-05 24.2 0.0 1.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OEU19041.1 - 0.0049 16.1 0.0 0.039 13.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU19041.1 - 0.006 16.6 0.3 0.02 14.9 0.2 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OEU19041.1 - 0.025 13.8 0.1 0.063 12.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU19041.1 - 0.12 11.4 0.4 0.35 9.9 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A 7tm_3 PF00003.22 OEU19042.1 - 2.3e-11 43.9 28.0 1.7e-10 41.1 27.6 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4079 PF13301.6 OEU19042.1 - 0.59 10.3 4.7 0.94 9.6 0.3 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) zf-MYND PF01753.18 OEU19043.1 - 4.8e-07 29.7 18.4 1.2e-06 28.4 18.4 1.8 1 0 0 1 1 1 1 MYND finger zf-3CxxC_2 PF17180.4 OEU19044.1 - 1.2e-08 35.5 7.6 1.2e-08 35.5 7.6 2.1 1 1 1 2 2 2 1 Zinc-binding domain zf-3CxxC PF13695.6 OEU19044.1 - 1.2 9.6 16.5 5 7.7 10.7 3.7 2 1 0 2 2 2 0 Zinc-binding domain Cytochrom_c3_2 PF14537.6 OEU19044.1 - 2.1 8.9 8.8 4.9 7.7 8.8 1.6 1 0 0 1 1 1 0 Cytochrome c3 adh_short PF00106.25 OEU19045.1 - 7.7e-12 45.1 0.0 1.4e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU19045.1 - 4.8e-07 29.6 0.0 8.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 OEU19045.1 - 1.9e-05 24.9 0.1 3.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OEU19045.1 - 0.00014 21.8 0.1 0.00022 21.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OEU19045.1 - 0.004 17.2 0.1 0.0062 16.6 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase pPIWI_RE_REase PF18154.1 OEU19047.1 - 0.00013 21.9 0.3 0.29 11.1 0.1 2.3 2 0 0 2 2 2 2 REase associating with pPIWI_RE DUF2442 PF10387.9 OEU19047.1 - 0.036 14.4 0.1 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Arc_trans_TRASH PF08394.10 OEU19047.1 - 0.064 13.6 0.0 21 5.6 0.0 2.7 2 0 0 2 2 2 0 Archaeal TRASH domain CusF_Ec PF11604.8 OEU19047.1 - 0.16 12.0 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF ETRAMP PF09716.10 OEU19047.1 - 1.9 8.6 7.6 6.8 6.8 0.2 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) UN_NPL4 PF11543.8 OEU19049.1 - 0.027 14.9 0.1 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 IRK_C PF17655.1 OEU19051.1 - 9.1e-11 41.7 0.2 9.5e-07 28.6 0.0 2.5 2 1 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OEU19051.1 - 3.3e-06 27.0 3.2 6.1e-06 26.1 3.2 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OEU19051.1 - 0.00094 19.1 4.5 0.002 18.0 4.5 1.6 1 0 0 1 1 1 1 Ion channel zf-C2H2_4 PF13894.6 OEU19051.1 - 0.0079 17.0 0.2 0.027 15.3 0.2 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-HC5HC2H PF13771.6 OEU19051.1 - 0.0092 16.2 5.8 0.23 11.7 3.6 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-C2H2 PF00096.26 OEU19051.1 - 0.026 15.0 0.0 0.088 13.3 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-HC5HC2H_2 PF13832.6 OEU19051.1 - 0.078 13.1 3.3 0.07 13.3 0.9 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain SLATT_5 PF18160.1 OEU19052.1 - 0.0008 18.8 0.0 0.0019 17.6 0.0 1.6 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 DUF2975 PF11188.8 OEU19052.1 - 0.061 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Ni_hydr_CYTB PF01292.20 OEU19052.1 - 0.13 11.9 0.9 0.23 11.1 0.9 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 RcsC PF09456.10 OEU19053.1 - 0.084 12.9 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Spt5_N PF11942.8 OEU19053.1 - 1.4 9.9 9.2 11 7.1 2.1 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-Dof PF02701.15 OEU19054.1 - 0.015 15.5 3.7 0.015 15.5 2.8 1.5 1 1 0 1 1 1 0 Dof domain, zinc finger IRK PF01007.20 OEU19055.1 - 1.2e-08 34.8 2.9 2.3e-08 34.0 2.9 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 OEU19055.1 - 2.9e-07 30.2 1.1 9e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain zf-Di19 PF05605.12 OEU19055.1 - 0.014 15.7 0.5 0.14 12.5 0.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OEU19055.1 - 0.027 15.3 1.4 0.091 13.6 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger YMF19 PF02326.15 OEU19055.1 - 0.033 15.0 1.7 0.033 15.0 1.7 3.9 4 0 0 4 4 4 0 Plant ATP synthase F0 Ion_trans_2 PF07885.16 OEU19055.1 - 0.15 12.0 8.8 0.36 10.8 8.8 1.6 1 0 0 1 1 1 0 Ion channel CENP-B_dimeris PF09026.10 OEU19055.1 - 4.4 7.8 26.7 0.1 13.0 12.7 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain LRR_4 PF12799.7 OEU19056.1 - 1.6e-23 82.4 97.1 9.2e-05 22.7 7.4 11.8 4 2 11 16 16 16 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU19056.1 - 9.9e-17 60.5 76.4 4.1e-05 23.2 2.7 8.4 2 2 7 10 10 10 10 Leucine rich repeat LRR_9 PF14580.6 OEU19056.1 - 0.32 10.5 13.8 3.2 7.2 1.1 3.8 2 1 1 3 3 3 0 Leucine-rich repeat Notch PF00066.17 OEU19056.1 - 9.5 6.8 10.5 34 5.0 10.5 2.0 1 0 0 1 1 1 0 LNR domain RTT107_BRCT_5 PF16770.5 OEU19057.1 - 0.027 14.4 0.2 0.076 12.9 0.1 1.7 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF5523 PF17661.1 OEU19058.1 - 0.0058 16.4 2.2 0.01 15.6 2.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Myb_Cef PF11831.8 OEU19058.1 - 0.014 15.0 2.2 0.025 14.1 2.2 1.4 1 0 0 1 1 1 0 pre-mRNA splicing factor component Serglycin PF04360.12 OEU19058.1 - 0.29 11.1 4.0 1.1 9.2 0.1 3.1 2 1 1 3 3 3 0 Serglycin CPBP PF02517.16 OEU19059.1 - 5.4e-17 62.0 2.7 6.3e-17 61.7 0.2 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease adh_short PF00106.25 OEU19060.1 - 5.6e-20 71.6 0.0 1.6e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU19060.1 - 1.6e-12 47.5 0.0 2.3e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU19060.1 - 1.4e-05 25.1 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU19060.1 - 0.016 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU19060.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Mid2 PF04478.12 OEU19064.1 - 0.0036 17.1 0.4 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 OEU19064.1 - 0.085 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Podoplanin DUF2407_C PF13373.6 OEU19064.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF1391 PF07151.12 OEU19064.1 - 0.24 11.3 0.8 0.54 10.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) LMBR1 PF04791.16 OEU19065.1 - 0.0024 16.9 0.6 0.0024 16.9 0.6 1.5 2 0 0 2 2 2 1 LMBR1-like membrane protein MRF_C2 PF13888.6 OEU19065.1 - 0.015 15.2 5.0 0.037 13.9 5.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 HeH PF12949.7 OEU19065.1 - 0.082 12.6 0.7 0.33 10.7 0.2 2.2 3 0 0 3 3 3 0 HeH/LEM domain CSG2 PF16965.5 OEU19065.1 - 4.3 6.2 7.8 0.15 10.9 0.6 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Renin_r PF07850.14 OEU19065.1 - 9 7.0 8.7 0.36 11.5 0.3 3.1 3 0 0 3 3 3 0 Renin receptor-like protein SYF2 PF08231.12 OEU19067.1 - 0.021 15.2 1.0 0.021 15.2 1.0 2.5 2 1 0 2 2 2 0 SYF2 splicing factor DUF3267 PF11667.8 OEU19067.1 - 0.29 11.4 2.1 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative zincin peptidase Exonuc_VII_L PF02601.15 OEU19067.1 - 1.5 8.3 9.3 2.5 7.6 9.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pam16 PF03656.13 OEU19068.1 - 1.2e-16 60.9 0.8 1.6e-16 60.5 0.8 1.1 1 0 0 1 1 1 1 Pam16 OSCP PF00213.18 OEU19069.1 - 1.4e-45 155.6 3.4 1.4e-45 155.6 3.4 1.3 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit FtsZ_C PF12327.8 OEU19069.1 - 0.0084 16.4 0.2 0.023 15.0 0.2 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain DUF4183 PF13799.6 OEU19069.1 - 0.064 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) ThiC-associated PF13667.6 OEU19069.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain 7tm_3 PF00003.22 OEU19070.1 - 1.3e-22 80.7 15.4 2.9e-21 76.3 14.1 2.2 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Amnionless PF14828.6 OEU19070.1 - 0.014 14.3 0.1 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 Amnionless NicO PF03824.16 OEU19070.1 - 0.21 10.9 3.5 0.28 10.5 0.0 2.6 2 0 0 2 2 2 0 High-affinity nickel-transport protein WBP-1 PF11669.8 OEU19070.1 - 0.26 12.0 4.5 0.28 11.8 0.0 3.1 3 0 0 3 3 3 0 WW domain-binding protein 1 COX14 PF14880.6 OEU19070.1 - 0.54 10.1 0.0 0.54 10.1 0.0 3.2 3 0 0 3 3 3 0 Cytochrome oxidase c assembly S1 PF00575.23 OEU19071.1 - 1.1e-33 115.4 0.1 5e-17 62.0 0.0 3.2 3 0 0 3 3 3 3 S1 RNA binding domain D-ser_dehydrat PF14031.6 OEU19071.1 - 0.047 14.4 0.0 8.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Putative serine dehydratase domain Gp37 PF09646.10 OEU19071.1 - 0.067 13.0 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Gp37 protein WW PF00397.26 OEU19073.1 - 8.5e-23 80.1 10.7 2e-11 43.7 0.8 2.2 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OEU19073.1 - 0.0002 21.6 2.3 0.14 12.5 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 OEU19073.1 - 0.01 15.7 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat Hydrolase_2 PF07486.12 OEU19073.1 - 0.081 13.8 0.1 13 6.7 0.0 2.0 1 1 1 2 2 2 0 Cell Wall Hydrolase baeRF_family7 PF18849.1 OEU19074.1 - 0.11 12.7 1.3 0.27 11.4 1.3 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 Egh16-like PF11327.8 OEU19077.1 - 0.075 13.4 0.0 0.081 13.3 0.0 1.1 1 0 0 1 1 1 0 Egh16-like virulence factor Lipase_3 PF01764.25 OEU19078.1 - 4.1e-15 55.9 0.0 8.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OEU19078.1 - 0.021 14.1 0.0 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 OEU19078.1 - 0.029 13.9 0.3 7.1 6.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 OEU19078.1 - 0.17 12.5 0.0 0.82 10.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family zf-C2H2_4 PF13894.6 OEU19080.1 - 0.014 16.2 11.7 0.024 15.4 0.1 3.8 2 1 1 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 OEU19080.1 - 0.051 14.2 0.1 0.051 14.2 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain UPF0029 PF01205.19 OEU19080.1 - 0.057 13.8 1.9 0.69 10.3 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 TP53IP5 PF15331.6 OEU19080.1 - 0.12 12.6 9.1 0.58 10.3 9.1 1.9 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-C2H2 PF00096.26 OEU19080.1 - 0.51 10.9 0.2 0.51 10.9 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Phage_integrase PF00589.22 OEU19081.1 - 0.038 13.8 2.1 3 7.6 0.1 2.7 3 0 0 3 3 3 0 Phage integrase family Notch PF00066.17 OEU19082.1 - 0.55 10.7 9.6 0.11 12.9 5.6 2.0 1 1 0 1 1 1 0 LNR domain DUF1754 PF08555.10 OEU19082.1 - 8.1 7.3 14.0 0.33 11.8 6.9 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Aa_trans PF01490.18 OEU19083.1 - 4.1e-19 68.6 15.2 1.1e-13 50.7 10.0 2.8 3 0 0 3 3 3 2 Transmembrane amino acid transporter protein SDA1 PF05285.12 OEU19083.1 - 0.00012 21.7 28.1 0.00082 18.9 0.0 2.3 1 1 1 2 2 2 1 SDA1 Mucin PF01456.17 OEU19083.1 - 0.73 9.8 10.2 1.2 9.1 5.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 OEU19083.1 - 5.6 6.9 8.9 1.5 8.8 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SNARE_assoc PF09335.11 OEU19084.1 - 8.4e-16 58.5 2.8 8.4e-16 58.5 2.8 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF997 PF06196.12 OEU19084.1 - 1.8 8.7 7.2 0.5 10.4 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF2207 PF09972.9 OEU19084.1 - 2.1 7.0 5.8 4.6 5.9 5.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RAMP4 PF06624.12 OEU19084.1 - 5.5 7.1 4.9 2.6 8.2 0.1 2.4 1 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Ribosomal_L27A PF00828.19 OEU19086.1 - 7.6e-28 97.8 0.1 1.1e-27 97.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 OEU19086.1 - 0.033 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Peripla_BP_4 PF13407.6 OEU19087.1 - 7.1e-11 42.2 7.3 1.1e-08 34.9 0.7 4.4 4 2 0 4 4 4 2 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 OEU19087.1 - 0.042 13.3 0.1 0.38 10.1 0.0 2.4 3 0 0 3 3 3 0 Periplasmic binding proteins and sugar binding domain of LacI family Prokineticin PF06607.11 OEU19087.1 - 1.4 9.3 4.5 1.3 9.4 1.1 2.4 2 0 0 2 2 2 0 Prokineticin Ank_2 PF12796.7 OEU19090.1 - 4.5e-06 27.2 0.0 0.13 12.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU19090.1 - 0.00043 20.8 0.1 2 9.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU19090.1 - 0.022 15.3 0.1 19 6.2 0.0 4.0 4 1 0 4 4 4 0 Ankyrin repeat Peptidase_A2B PF12384.8 OEU19090.1 - 0.041 13.4 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Scramblase PF03803.15 OEU19093.1 - 2.5e-28 98.9 0.0 1.3e-27 96.6 0.0 1.9 1 1 0 1 1 1 1 Scramblase Dynamin_N PF00350.23 OEU19094.1 - 1.4e-06 28.4 0.6 4.5e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin family 7tm_3 PF00003.22 OEU19095.1 - 4.5e-13 49.5 26.3 2.7e-12 46.9 26.3 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR LRR19-TM PF15176.6 OEU19095.1 - 0.039 14.0 5.6 0.25 11.3 0.0 3.6 4 0 0 4 4 4 0 Leucine-rich repeat family 19 TM domain Serinc PF03348.15 OEU19098.1 - 2.1e-18 66.5 0.2 2.3e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Saf_2TM PF18303.1 OEU19098.1 - 0.0025 17.4 0.4 0.0034 17.0 0.3 1.3 1 1 0 1 1 1 1 SAVED-fused 2TM effector domain DUF3439 PF11921.8 OEU19099.1 - 0.18 11.8 10.6 0.19 11.7 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Fasciclin PF02469.22 OEU19101.1 - 3e-18 66.2 0.0 5.8e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU19101.1 - 6.1e-06 27.0 0.4 2.5e-05 25.0 0.4 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Kunitz_BPTI PF00014.23 OEU19101.1 - 0.5 10.6 2.5 1 9.6 0.3 2.5 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain ETRAMP PF09716.10 OEU19103.1 - 0.013 15.6 2.3 0.013 15.6 2.3 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 OEU19103.1 - 0.013 15.8 2.3 0.013 15.8 2.3 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal AgrB PF04647.15 OEU19103.1 - 0.06 12.6 2.0 0.12 11.7 2.0 1.4 1 0 0 1 1 1 0 Accessory gene regulator B SARAF PF06682.12 OEU19103.1 - 0.09 12.4 4.5 0.19 11.4 4.5 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis G0-G1_switch_2 PF15103.6 OEU19103.1 - 0.22 12.0 3.9 1.1 9.7 4.0 2.1 1 1 0 1 1 1 0 G0/G1 switch protein 2 SID-1_RNA_chan PF13965.6 OEU19103.1 - 0.97 7.8 7.7 1.4 7.2 7.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DEC-1_N PF04625.13 OEU19103.1 - 1.7 7.5 10.6 2.6 6.9 10.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Presenilin PF01080.17 OEU19103.1 - 3 6.5 5.6 5.4 5.7 5.6 1.5 1 0 0 1 1 1 0 Presenilin Sulfotransfer_3 PF13469.6 OEU19103.1 - 3.1 8.1 11.0 2.1 8.7 0.3 3.8 3 1 1 4 4 4 0 Sulfotransferase family CLN3 PF02487.17 OEU19103.1 - 3.5 6.6 5.2 5.7 5.9 5.2 1.3 1 0 0 1 1 1 0 CLN3 protein DUF4834 PF16118.5 OEU19103.1 - 3.6 8.6 15.4 0.095 13.7 6.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Renin_r PF07850.14 OEU19103.1 - 5.3 7.7 8.9 0.38 11.4 0.3 2.9 1 1 0 2 2 2 0 Renin receptor-like protein Fasciclin PF02469.22 OEU19104.1 - 3.8e-19 69.2 0.0 6.4e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain LPMO_10 PF03067.15 OEU19104.1 - 3.3e-05 24.6 1.2 0.00027 21.7 1.2 2.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PaO PF08417.12 OEU19105.1 - 3.8e-15 55.8 0.0 1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Pheophorbide a oxygenase Rieske PF00355.26 OEU19105.1 - 2.8e-14 52.8 0.0 6.4e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain YqzE PF14038.6 OEU19105.1 - 0.053 13.5 1.0 0.37 10.8 0.4 2.5 3 0 0 3 3 3 0 YqzE-like protein Rieske_2 PF13806.6 OEU19105.1 - 0.12 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain FH2 PF02181.23 OEU19106.1 - 3.2e-36 125.2 0.2 3.6e-36 125.1 0.2 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain V-SNARE_C PF12352.8 OEU19107.1 - 9.7e-13 48.2 1.4 9.7e-13 48.2 1.4 2.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus ANAPC4 PF12896.7 OEU19107.1 - 0.052 13.0 0.6 1.1 8.7 0.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Sec20 PF03908.13 OEU19107.1 - 0.056 13.4 2.1 0.34 10.8 0.0 2.7 2 1 1 3 3 3 0 Sec20 Edc3_linker PF16598.5 OEU19107.1 - 0.35 11.5 2.9 0.68 10.6 0.5 2.2 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 kleA_kleC PF17383.2 OEU19107.1 - 0.38 11.1 1.4 0.97 9.8 0.1 2.3 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A TACC_C PF05010.14 OEU19107.1 - 0.4 10.4 4.6 1.2 8.9 0.5 2.6 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Striatin PF08232.12 OEU19107.1 - 0.71 10.5 6.5 0.12 12.9 1.2 1.9 1 1 1 2 2 2 0 Striatin family Bromodomain PF00439.25 OEU19108.1 - 1.7e-09 37.6 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Bromodomain LRR_8 PF13855.6 OEU19109.1 - 5.5e-05 22.8 0.1 1.3 8.8 0.0 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU19109.1 - 0.00022 21.5 0.4 9.3 6.8 0.0 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) MgtE_N PF03448.17 OEU19110.1 - 0.15 12.7 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Pyr_redox_2 PF07992.14 OEU19111.1 - 1.6e-45 155.6 0.0 3e-45 154.7 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU19111.1 - 9.1e-12 45.4 0.0 2.3e-09 37.7 0.0 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU19111.1 - 0.043 14.0 0.0 14 6.0 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OEU19111.1 - 0.06 12.6 1.1 3.9 6.6 0.0 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Aconitase PF00330.20 OEU19111.1 - 0.069 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) UPF0242 PF06785.11 OEU19113.1 - 0.59 10.2 6.3 0.97 9.5 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus S_2TMBeta PF18153.1 OEU19113.1 - 9 6.0 8.6 16 5.2 8.6 1.3 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain SOG2 PF10428.9 OEU19114.1 - 0.017 14.3 6.0 0.023 13.9 6.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FMN_bind PF04205.14 OEU19114.1 - 0.08 13.5 7.8 0.11 13.1 4.6 2.8 2 1 0 2 2 2 0 FMN-binding domain DUF572 PF04502.13 OEU19114.1 - 0.49 10.0 18.1 0.77 9.3 18.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.13 OEU19114.1 - 0.65 8.5 23.6 0.85 8.1 23.6 1.1 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 OEU19114.1 - 2.8 6.6 18.5 0.11 11.2 7.7 2.2 2 0 0 2 2 2 0 Presenilin Yae1_N PF09811.9 OEU19115.1 - 1.8e-07 30.7 77.1 6.8 6.5 3.4 17.2 3 3 6 9 9 9 4 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU19115.1 - 0.19 11.8 0.1 59 3.7 0.0 4.0 1 1 1 3 3 3 0 Outer membrane protein beta-barrel domain MtrG PF04210.13 OEU19115.1 - 3.7 7.5 61.6 2.5 8.0 1.0 13.2 2 2 10 12 12 12 0 Tetrahydromethanopterin S-methyltransferase, subunit G PT PF04886.12 OEU19116.1 - 4.8e-07 29.2 24.4 0.0027 17.2 10.0 3.3 1 1 1 2 2 2 2 PT repeat CCSAP PF15748.5 OEU19117.1 - 0.16 12.1 23.1 0.067 13.4 19.2 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Borrelia_P83 PF05262.11 OEU19117.1 - 0.18 10.3 15.8 0.25 9.8 15.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_11 PF08241.12 OEU19118.1 - 9.8e-14 51.8 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU19118.1 - 7.8e-11 42.0 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19118.1 - 7.9e-11 42.5 0.0 2.4e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU19118.1 - 2e-06 28.4 0.0 5.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19118.1 - 8.9e-05 22.4 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU19118.1 - 0.0002 20.8 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 OEU19118.1 - 0.087 12.7 0.0 0.55 10.0 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase PT PF04886.12 OEU19121.1 - 1.6e-06 27.6 66.6 0.00049 19.6 14.1 6.1 1 1 3 4 4 4 3 PT repeat NlpE PF04170.12 OEU19121.1 - 0.076 14.0 0.6 0.14 13.1 0.6 1.4 1 0 0 1 1 1 0 NlpE N-terminal domain ShK PF01549.24 OEU19121.1 - 0.75 10.4 7.8 2.2 8.9 7.6 1.9 1 1 1 2 2 2 0 ShK domain-like PT PF04886.12 OEU19122.1 - 0.0071 15.9 32.4 0.31 10.6 26.3 3.0 2 1 0 2 2 2 2 PT repeat ShK PF01549.24 OEU19122.1 - 0.0078 16.7 19.2 0.026 15.1 6.5 3.0 3 1 0 3 3 3 2 ShK domain-like PT PF04886.12 OEU19123.1 - 0.00056 19.4 75.1 0.034 13.7 25.3 3.0 2 1 0 2 2 2 2 PT repeat Carla_C4 PF01623.17 OEU19123.1 - 0.0024 17.8 0.1 0.0067 16.4 0.1 1.8 1 1 0 1 1 1 1 Carlavirus putative nucleic acid binding protein ShK PF01549.24 OEU19123.1 - 0.0063 17.0 16.2 0.69 10.5 7.0 3.5 3 1 0 3 3 3 2 ShK domain-like DUF2973 PF11189.8 OEU19123.1 - 0.27 11.4 0.2 0.69 10.0 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) Spermine_synth PF01564.17 OEU19124.1 - 1.7e-25 89.5 0.0 2.1e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF3216 PF11505.8 OEU19127.1 - 1.9 8.7 5.7 12 6.1 0.2 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3216) PHD PF00628.29 OEU19128.1 - 1.5e-09 37.6 9.3 2.2e-09 37.1 9.3 1.3 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 OEU19128.1 - 0.00074 19.6 4.1 0.00074 19.6 4.1 1.9 1 1 1 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 OEU19128.1 - 0.0027 17.3 3.6 0.0027 17.3 3.6 1.2 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OEU19128.1 - 0.72 9.8 11.3 0.043 13.7 6.4 1.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Bromodomain PF00439.25 OEU19129.1 - 3.6e-15 55.8 0.0 3.9e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 OEU19130.1 - 2.2e-17 64.0 0.1 2.2e-16 60.7 0.1 2.2 1 1 0 1 1 1 1 SET domain AF0941-like PF14591.6 OEU19130.1 - 0.016 15.7 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 AF0941-like MMS1_N PF10433.9 OEU19131.1 - 9.4e-87 291.7 0.0 4.5e-56 190.5 0.0 2.5 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OEU19131.1 - 2.8e-73 247.1 0.0 8.3e-73 245.5 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region BUD22 PF09073.10 OEU19131.1 - 0.63 9.3 16.9 0.019 14.3 8.6 2.1 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 OEU19131.1 - 1.8 8.3 21.9 2.9 7.5 18.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LRR_4 PF12799.7 OEU19132.1 - 0.00034 20.9 3.0 0.31 11.5 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OEU19132.1 - 0.031 13.8 0.3 0.33 10.4 0.0 2.3 1 1 0 2 2 2 0 Leucine-rich repeat Fasciclin PF02469.22 OEU19134.1 - 7.6e-35 119.9 0.0 8.6e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Herpes_UL32 PF06070.11 OEU19136.1 - 0.071 10.9 5.7 0.12 10.2 5.7 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF4175 PF13779.6 OEU19136.1 - 3.5 5.4 11.1 5.2 4.9 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 OEU19136.1 - 6.7 5.4 7.3 11 4.7 7.3 1.4 1 0 0 1 1 1 0 Presenilin CIAPIN1 PF05093.13 OEU19136.1 - 8.3 7.0 9.2 29 5.2 2.9 2.9 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Gly-zipper_Omp PF13488.6 OEU19139.1 - 0.0039 17.2 52.2 6.8 6.8 8.2 5.7 2 1 2 4 4 4 1 Glycine zipper DUF456 PF04306.13 OEU19139.1 - 0.046 14.0 12.4 3.7 7.8 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.15 OEU19139.1 - 0.22 11.4 40.3 3.9 7.4 4.8 4.7 2 1 2 4 4 4 0 Glycine zipper 2TM domain Senescence PF06911.12 OEU19139.1 - 4.9 7.4 26.5 5.4 7.3 1.0 3.9 1 1 1 3 3 3 0 Senescence-associated protein Gly-zipper_YMGG PF13441.6 OEU19139.1 - 5.2 6.9 42.0 5.4 6.9 7.1 4.8 2 1 1 3 3 3 0 YMGG-like Gly-zipper Transgly_assoc PF04226.13 OEU19139.1 - 8.3 6.8 26.4 0.31 11.3 5.0 5.0 1 1 2 3 3 3 0 Transglycosylase associated protein Sulfotransfer_3 PF13469.6 OEU19140.1 - 1.8e-11 44.9 0.0 3.6e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 OEU19140.1 - 0.0078 15.7 0.2 0.12 11.9 0.2 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 OEU19140.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase domain Sulfatase PF00884.23 OEU19142.1 - 2.2e-10 40.4 0.0 2.5e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Rhamno_transf PF11316.8 OEU19143.1 - 1.6e-10 40.8 3.7 0.00013 21.4 0.4 3.3 3 1 0 3 3 3 2 Putative rhamnosyl transferase DUF3671 PF12420.8 OEU19143.1 - 0.024 14.7 0.3 0.15 12.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function Caldesmon PF02029.15 OEU19143.1 - 0.061 12.1 45.9 0.86 8.3 28.8 3.3 1 1 0 2 2 2 0 Caldesmon Ank_2 PF12796.7 OEU19144.1 - 2.1e-06 28.2 0.0 0.16 12.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) INTS5_N PF14837.6 OEU19144.1 - 0.088 12.4 0.2 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Pox_EPC_I2-L1 PF12575.8 OEU19145.1 - 0.1 12.9 3.7 0.14 12.4 3.4 1.3 1 1 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 CAP_N PF01213.19 OEU19145.1 - 0.74 9.2 6.8 0.8 9.1 6.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aa_trans PF01490.18 OEU19146.1 - 1.5e-49 168.8 25.3 2e-49 168.4 25.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU19146.1 - 4.2e-07 29.3 10.6 4.2e-07 29.3 10.6 2.4 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 OEU19146.1 - 2.5e-05 23.2 1.0 2.5e-05 23.2 1.0 4.0 5 0 0 5 5 5 2 Spore germination protein MASE2 PF05230.11 OEU19146.1 - 0.12 12.4 3.0 0.21 11.7 0.0 3.0 3 0 0 3 3 3 0 MASE2 domain Peptidase_S49_N PF08496.10 OEU19148.1 - 0.03 14.4 0.3 0.036 14.1 0.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 OEU19148.1 - 0.24 11.1 0.6 0.27 11.0 0.6 1.0 1 0 0 1 1 1 0 Connexin TPT PF03151.16 OEU19149.1 - 6.9e-92 307.9 6.5 8.5e-92 307.6 6.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OEU19149.1 - 1.3e-15 57.8 14.9 2.5e-08 34.2 4.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OEU19149.1 - 0.038 13.2 4.5 0.32 10.1 0.4 1.9 1 1 1 2 2 2 0 UAA transporter family Thioredoxin PF00085.20 OEU19150.1 - 2.5e-23 82.0 0.5 2.3e-22 78.9 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU19150.1 - 1.7e-06 28.3 0.3 0.011 16.0 0.0 3.4 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU19150.1 - 3.4e-06 27.5 0.2 1.4e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU19150.1 - 8.2e-06 25.7 0.4 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OEU19150.1 - 1.2e-05 25.0 0.9 4.3e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 OEU19150.1 - 0.013 15.7 0.1 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like Cwf_Cwc_15 PF04889.12 OEU19150.1 - 0.037 13.8 15.4 0.048 13.4 15.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin_4 PF13462.6 OEU19150.1 - 0.065 13.4 1.1 0.95 9.6 0.0 2.6 1 1 2 3 3 3 0 Thioredoxin NOA36 PF06524.12 OEU19150.1 - 0.2 10.9 15.4 0.28 10.5 15.4 1.3 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 OEU19150.1 - 0.49 8.3 12.5 0.62 8.0 12.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RXT2_N PF08595.11 OEU19150.1 - 1.8 8.6 8.5 2.7 8.0 8.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal ANAPC15 PF15243.6 OEU19150.1 - 2.8 8.4 14.5 6.2 7.3 14.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 CENP-B_dimeris PF09026.10 OEU19150.1 - 5.5 7.5 20.1 13 6.2 20.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3295 PF11702.8 OEU19150.1 - 6 6.1 13.8 7.3 5.8 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TPR_12 PF13424.6 OEU19151.1 - 9.6e-66 218.1 15.4 5.6e-13 49.0 0.0 6.4 4 2 1 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 OEU19151.1 - 2.2e-45 151.3 9.8 3.3e-09 36.3 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19151.1 - 3.1e-33 112.2 13.4 0.0012 18.6 0.3 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19151.1 - 1.5e-29 99.7 18.5 0.0041 17.1 0.4 9.6 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19151.1 - 3.7e-24 82.9 9.6 0.0083 16.1 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 OEU19151.1 - 2.4e-22 78.3 10.0 0.0024 17.5 0.0 9.9 10 0 0 10 10 10 4 TPR repeat TPR_8 PF13181.6 OEU19151.1 - 3.9e-22 76.5 19.5 0.00012 22.0 0.0 9.5 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 OEU19151.1 - 4.6e-18 65.6 9.8 0.0055 17.3 0.0 8.5 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OEU19151.1 - 1.3e-16 59.8 9.2 0.23 12.4 0.0 9.3 7 3 3 10 10 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU19151.1 - 2.2e-12 47.0 2.0 0.00011 21.7 0.5 3.3 1 1 1 3 3 3 3 MalT-like TPR region TPR_17 PF13431.6 OEU19151.1 - 3.4e-09 36.5 2.6 1.2 9.7 0.0 7.3 9 0 0 9 9 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU19151.1 - 3.4e-06 26.4 9.8 18 4.9 0.0 8.5 9 0 0 9 9 9 0 SHNi-TPR TPR_19 PF14559.6 OEU19151.1 - 4.5e-06 27.1 7.1 1.5 9.4 0.2 6.1 4 1 4 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU19151.1 - 5.5e-06 26.5 5.9 2.5 8.4 0.1 6.3 3 3 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OEU19151.1 - 0.00012 22.1 1.3 3.2 8.0 0.0 5.1 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU19151.1 - 0.00022 21.6 10.9 2.9 8.7 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat MIT PF04212.18 OEU19151.1 - 0.00033 20.7 1.1 46 4.2 0.0 5.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 OEU19151.1 - 0.00043 20.6 4.1 34 5.5 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF5113 PF17140.4 OEU19151.1 - 0.0012 18.7 0.8 14 5.4 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5113) RPN7 PF10602.9 OEU19151.1 - 0.005 16.6 1.4 0.26 11.0 0.1 3.4 3 2 1 4 4 4 1 26S proteasome subunit RPN7 TPR_15 PF13429.6 OEU19151.1 - 0.009 15.3 1.3 0.89 8.7 0.0 4.1 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF357 PF04010.13 OEU19151.1 - 0.036 14.1 0.2 2.2 8.4 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF4810 PF16068.5 OEU19151.1 - 0.04 14.5 0.3 1 9.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_21 PF09976.9 OEU19151.1 - 0.068 12.9 4.0 18 5.0 0.0 4.8 4 3 2 6 6 6 0 Tetratricopeptide repeat-like domain AIP3 PF03915.13 OEU19151.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 PPR PF01535.20 OEU19151.1 - 0.17 12.2 2.1 3.3 8.2 0.0 4.4 6 0 0 6 6 2 0 PPR repeat ubiquitin PF00240.23 OEU19152.1 - 7.4e-12 44.8 0.1 1.5e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OEU19152.1 - 2e-06 27.5 0.5 1.1e-05 25.2 0.5 2.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 OEU19152.1 - 0.00022 21.0 0.3 0.0005 19.8 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2407 PF10302.9 OEU19152.1 - 0.00085 19.9 0.1 0.0041 17.7 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 OEU19152.1 - 0.0021 18.1 0.7 0.0056 16.7 0.1 1.9 2 0 0 2 2 2 1 HOIP UBA domain pair STI1 PF17830.1 OEU19152.1 - 0.0043 16.9 11.0 0.0043 16.9 11.0 7.7 8 1 1 9 9 9 2 STI1 domain Ubiquitin_4 PF18036.1 OEU19152.1 - 0.069 13.2 0.2 0.5 10.4 0.2 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 OEU19152.1 - 0.074 12.8 0.2 0.074 12.8 0.2 3.2 4 0 0 4 4 4 0 CUE domain Rad60-SLD PF11976.8 OEU19152.1 - 0.082 12.8 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like BSD PF03909.17 OEU19152.1 - 0.28 11.2 6.8 3 7.9 0.6 3.9 3 1 1 4 4 4 0 BSD domain HECW1_helix PF18436.1 OEU19152.1 - 0.77 9.9 2.6 1.6 8.9 0.4 2.6 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Peptidase_C48 PF02902.19 OEU19153.1 - 1.4e-23 83.9 2.2 1.7e-23 83.6 2.2 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ATG11 PF10377.9 OEU19154.1 - 0.017 15.2 0.4 0.033 14.2 0.4 1.4 1 0 0 1 1 1 0 Autophagy-related protein 11 MHCassoc_trimer PF08831.10 OEU19154.1 - 0.16 12.0 1.0 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain DUF1125 PF06563.11 OEU19156.1 - 0.0032 17.3 0.1 0.0099 15.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1125) RecO_N PF11967.8 OEU19156.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Recombination protein O N terminal DUF5600 PF18150.1 OEU19156.1 - 0.59 10.7 3.1 1.8 9.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) Rep-A_N PF04057.12 OEU19157.1 - 2.3e-09 37.2 0.1 6.1e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.9 OEU19157.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Dna2 PF08696.11 OEU19157.1 - 0.2 11.4 1.1 0.32 10.8 0.3 1.6 2 0 0 2 2 2 0 DNA replication factor Dna2 Spc110_C PF18520.1 OEU19160.1 - 8.4 6.1 6.5 23 4.7 0.4 2.9 1 1 2 3 3 3 0 Spindle pole body component 110 C-terminal domain Trypsin PF00089.26 OEU19161.1 - 1.1e-24 87.5 1.4 1.3e-24 87.2 1.4 1.0 1 0 0 1 1 1 1 Trypsin DUF4241 PF14025.6 OEU19164.1 - 0.027 14.8 0.1 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) FYDLN_acid PF09538.10 OEU19165.1 - 4.8 7.9 10.3 18 6.1 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DAO PF01266.24 OEU19166.1 - 5.9e-34 118.2 0.0 3.9e-33 115.5 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU19166.1 - 0.0045 16.3 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OEU19166.1 - 0.01 15.9 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OEU19166.1 - 0.046 12.6 0.0 0.86 8.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 OEU19166.1 - 0.095 13.3 0.5 3.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU19166.1 - 0.11 11.6 0.1 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A MCR PF18509.1 OEU19166.1 - 0.32 10.6 1.1 0.86 9.2 1.1 1.7 1 0 0 1 1 1 0 Magnetochrome domain RVT_2 PF07727.14 OEU19167.1 - 0.01 15.5 0.1 0.011 15.4 0.1 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_6 PF13516.6 OEU19170.1 - 1.5e-12 46.5 23.5 0.003 17.5 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat HTH_Tnp_Mu_2 PF09039.11 OEU19170.1 - 0.029 14.4 0.0 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Mu DNA binding, I gamma subdomain CHAT PF12770.7 OEU19170.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 CHAT domain LRR_4 PF12799.7 OEU19170.1 - 0.075 13.5 27.9 0.15 12.6 0.6 6.7 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) MatP_C PF17414.2 OEU19170.1 - 0.11 12.8 0.1 0.48 10.7 0.1 2.2 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain LRR_8 PF13855.6 OEU19170.1 - 1.1 9.1 22.5 7 6.5 0.2 6.1 4 2 1 5 5 5 0 Leucine rich repeat ATG13 PF10033.9 OEU19171.1 - 4.9e-14 52.6 0.0 9.6e-10 38.6 0.0 2.7 1 1 1 2 2 2 2 Autophagy-related protein 13 Erythro-docking PF09277.11 OEU19172.1 - 1.2e-05 25.1 0.2 0.021 14.7 0.1 2.6 2 0 0 2 2 2 2 Erythronolide synthase, docking NEMO PF11577.8 OEU19172.1 - 0.00035 20.5 5.4 0.25 11.4 0.5 2.5 2 0 0 2 2 2 2 NF-kappa-B essential modulator NEMO SYCE1 PF15233.6 OEU19172.1 - 0.00095 19.3 11.5 0.028 14.5 0.4 2.6 1 1 1 2 2 2 2 Synaptonemal complex central element protein 1 GIT_CC PF16559.5 OEU19172.1 - 0.0021 17.9 0.7 0.82 9.6 0.1 2.6 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor PT PF04886.12 OEU19172.1 - 0.004 16.7 36.9 61 3.3 36.9 2.5 1 1 0 1 1 1 0 PT repeat JIP_LZII PF16471.5 OEU19172.1 - 0.0065 16.6 12.1 0.38 11.0 4.1 3.5 1 1 2 3 3 3 2 JNK-interacting protein leucine zipper II MerR-DNA-bind PF09278.11 OEU19172.1 - 0.0098 16.4 10.0 0.31 11.6 3.3 2.7 3 0 0 3 3 2 2 MerR, DNA binding MRF_C1 PF13887.6 OEU19172.1 - 0.025 13.8 5.1 2.3 7.4 0.4 3.0 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Rab_bind PF16704.5 OEU19172.1 - 0.17 11.9 8.3 0.81 9.8 1.7 3.0 1 1 1 2 2 2 0 Rab binding domain DUF3584 PF12128.8 OEU19172.1 - 0.21 9.1 13.1 0.27 8.7 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSBP1 PF06825.12 OEU19172.1 - 0.27 11.1 3.0 11 6.0 0.3 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF3450 PF11932.8 OEU19172.1 - 0.31 10.3 10.3 0.19 11.0 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BsuBI_PstI_RE PF06616.11 OEU19172.1 - 0.55 9.5 2.8 3.5 6.9 1.0 2.1 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease domain DUF1664 PF07889.12 OEU19172.1 - 8.6 6.4 7.4 14 5.7 0.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FA_desaturase PF00487.24 OEU19173.1 - 5.8e-30 105.0 5.4 9.5e-30 104.3 5.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OEU19173.1 - 3.4e-08 33.5 0.0 8.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF285 PF03382.14 OEU19175.1 - 4.7e-143 468.6 86.2 8.3e-34 115.9 14.5 5.9 2 1 4 6 6 6 5 Mycoplasma protein of unknown function, DUF285 YolD PF08863.10 OEU19175.1 - 9.9e-09 35.1 0.0 8.1 6.6 0.0 6.7 3 2 3 6 6 6 2 YolD-like protein Phage_rep_O PF04492.13 OEU19175.1 - 5.4e-07 30.1 6.7 0.25 11.9 0.1 5.5 1 1 5 6 6 6 2 Bacteriophage replication protein O Pullulanase_Ins PF18494.1 OEU19175.1 - 9.3e-05 22.8 10.3 0.73 10.3 0.2 4.1 3 0 0 3 3 3 3 Pullulanase Ins domain DUF4686 PF15742.5 OEU19175.1 - 0.0014 17.8 0.9 0.49 9.5 0.1 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF4686) Blt1_C PF17183.4 OEU19175.1 - 1 9.0 13.3 1.5e+02 2.1 0.0 8.3 11 0 0 11 11 11 0 Get5 carboxyl domain YjcQ PF09639.10 OEU19175.1 - 1.6 9.0 3.6 28 5.0 0.1 4.0 5 0 0 5 5 5 0 YjcQ protein PSD4 PF07631.11 OEU19175.1 - 4.7 7.8 18.1 6.9 7.2 0.2 4.8 2 1 5 7 7 7 0 Protein of unknown function (DUF1592) SEP PF08059.13 OEU19177.1 - 1.9e-20 73.2 0.0 3.3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OEU19177.1 - 0.0057 16.8 0.0 0.0094 16.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain BDV_P10 PF06515.11 OEU19177.1 - 0.068 13.2 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Borna disease virus P10 protein Pinin_SDK_N PF04697.13 OEU19177.1 - 0.15 12.7 5.1 0.29 11.8 5.1 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region Cwf_Cwc_15 PF04889.12 OEU19177.1 - 2.5 7.8 6.2 3.8 7.2 6.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mrr_N PF14338.6 OEU19179.1 - 0.0003 20.8 0.0 0.062 13.4 0.0 2.8 2 1 0 2 2 2 1 Mrr N-terminal domain HTH_45 PF14947.6 OEU19179.1 - 0.02 14.9 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix Fe_dep_repress PF01325.19 OEU19179.1 - 0.035 14.3 0.1 0.99 9.6 0.1 2.6 2 1 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HemN_C PF06969.16 OEU19179.1 - 0.08 13.0 0.3 0.72 10.0 0.0 2.5 3 0 0 3 3 3 0 HemN C-terminal domain DUF2250 PF10007.9 OEU19179.1 - 0.095 12.8 0.2 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_46 PF15977.5 OEU19179.1 - 0.17 11.9 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Beach PF02138.18 OEU19180.1 - 1.1e-108 362.8 0.0 1.4e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OEU19180.1 - 1.9e-08 34.3 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH RRM_1 PF00076.22 OEU19181.1 - 1.1e-08 34.8 0.0 2e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 OEU19181.1 - 2.6e-05 24.0 2.6 0.0084 16.2 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU19181.1 - 0.00033 20.8 0.1 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SR-25 PF10500.9 OEU19181.1 - 0.0018 18.0 13.2 0.0018 18.0 13.2 4.5 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 OEU19181.1 - 0.0029 17.4 4.2 0.0094 15.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19181.1 - 0.074 13.3 2.1 0.74 10.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OEU19181.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat MoeA_N PF03453.17 OEU19182.1 - 0.095 12.5 1.8 0.14 11.9 1.8 1.3 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) ATF7IP_BD PF16788.5 OEU19182.1 - 3.9 7.5 14.1 4.9 7.2 14.1 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain Chi-conotoxin PF16981.5 OEU19182.1 - 5.4 7.3 7.9 0.49 10.7 1.2 2.5 3 0 0 3 3 3 0 chi-Conotoxin or t superfamily TMEM173 PF15009.6 OEU19183.1 - 0.037 13.2 0.4 0.075 12.2 0.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 173 DUF1772 PF08592.11 OEU19183.1 - 0.096 13.0 0.2 0.096 13.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Cadherin_C_2 PF16492.5 OEU19183.1 - 3.3 8.5 0.0 3.3 8.5 0.0 3.0 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal ArfGap PF01412.18 OEU19184.1 - 7.9e-33 113.0 1.3 9.6e-33 112.7 0.1 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 OEU19184.1 - 0.037 14.0 1.1 0.39 10.7 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Fasciclin PF02469.22 OEU19185.1 - 8.6e-34 116.5 0.0 1.3e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 OEU19187.1 - 2.9e-66 221.5 0.5 2.1e-32 112.1 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain HrcA_DNA-bdg PF03444.15 OEU19187.1 - 0.0021 17.7 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix transcription repressor, HrcA DNA-binding NPV_P10 PF05531.12 OEU19188.1 - 0.063 13.7 4.5 0.24 11.9 4.5 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2540 PF10802.8 OEU19188.1 - 0.13 12.3 0.1 0.46 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) MAT1 PF06391.13 OEU19188.1 - 3.2 7.5 10.7 0.21 11.4 2.5 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Peptidase_S8 PF00082.22 OEU19189.1 - 0.00012 21.4 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 Subtilase family DUF2633 PF11119.8 OEU19190.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Tetraspanin PF00335.20 OEU19190.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Tetraspanin family HSF_DNA-bind PF00447.17 OEU19192.1 - 1.5e-06 28.7 2.8 0.0011 19.5 0.2 2.9 3 1 0 3 3 3 2 HSF-type DNA-binding DUF3452 PF11934.8 OEU19192.1 - 0.25 10.9 3.9 0.72 9.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Androgen_recep PF02166.16 OEU19192.1 - 1.2 7.9 7.1 1.8 7.3 7.1 1.2 1 0 0 1 1 1 0 Androgen receptor DUF2271 PF10029.9 OEU19194.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) MTBP_C PF14920.6 OEU19194.1 - 0.1 12.3 7.4 0.22 11.3 7.4 1.5 1 0 0 1 1 1 0 MDM2-binding GH43_C2 PF17851.1 OEU19195.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain DUF1360 PF07098.11 OEU19196.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) DUF1676 PF07898.13 OEU19196.1 - 0.26 11.3 2.2 1.7 8.7 2.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) HMG_box PF00505.19 OEU19197.1 - 5.2e-09 36.4 15.0 1.7e-06 28.4 2.5 3.7 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU19197.1 - 1.8e-05 25.2 6.0 0.012 16.2 6.0 3.4 1 1 0 1 1 1 1 HMG-box domain DUF5320 PF17253.2 OEU19198.1 - 0.59 11.2 37.0 2.2 9.4 8.8 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) PT PF04886.12 OEU19201.1 - 1.1e-06 28.1 14.9 0.0011 18.5 3.3 3.0 1 1 1 2 2 2 2 PT repeat Yae1_N PF09811.9 OEU19202.1 - 1.9e-05 24.2 52.4 0.82 9.4 0.7 11.9 7 5 3 10 10 10 7 Essential protein Yae1, N terminal Gly-zipper_Omp PF13488.6 OEU19202.1 - 0.023 14.7 46.8 5.4 7.1 2.2 7.5 1 1 6 7 7 7 0 Glycine zipper OMP_b-brl PF13505.6 OEU19202.1 - 0.1 12.7 0.0 17 5.5 0.0 3.2 1 1 1 3 3 3 0 Outer membrane protein beta-barrel domain IGPD PF00475.18 OEU19202.1 - 2.9 8.2 10.8 48 4.2 0.1 5.8 1 1 2 4 4 4 0 Imidazoleglycerol-phosphate dehydratase HupE_UreJ_2 PF13795.6 OEU19202.1 - 7.5 6.2 8.3 0.69 9.5 2.6 2.3 2 1 0 2 2 2 0 HupE / UreJ protein Fasciclin PF02469.22 OEU19203.1 - 5.3e-35 120.4 0.0 6.2e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain 2OG-FeII_Oxy_2 PF13532.6 OEU19205.1 - 1.9e-30 106.6 0.0 3.4e-30 105.7 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AhpC-TSA PF00578.21 OEU19207.1 - 6.6e-28 97.1 0.0 8.8e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU19207.1 - 2.5e-15 56.5 0.0 3.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin MTD PF01993.18 OEU19207.1 - 0.0029 17.0 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase AhpC-TSA_2 PF13911.6 OEU19207.1 - 0.042 14.0 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme SHMT PF00464.19 OEU19208.1 - 5e-176 585.2 0.0 6.3e-176 584.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OEU19208.1 - 4.3e-05 22.9 0.0 6.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 OEU19208.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Tyrosinase PF00264.20 OEU19209.1 - 3.6e-21 76.5 3.6 3.6e-21 76.5 3.6 2.3 2 0 0 2 2 2 1 Common central domain of tyrosinase Folliculin_C PF16692.5 OEU19209.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Folliculin C-terminal domain FAD_binding_4 PF01565.23 OEU19210.1 - 5.7e-25 87.7 0.0 1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 OEU19210.1 - 2.9e-17 63.3 0.1 4.5e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase DXP_synthase_N PF13292.6 OEU19211.1 - 9.2e-105 349.7 0.0 3.2e-104 347.9 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 OEU19211.1 - 2.5e-37 128.3 0.0 3.9e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OEU19211.1 - 9.2e-20 70.8 0.0 2.9e-19 69.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 OEU19211.1 - 1.3e-06 27.6 0.0 0.0092 15.0 0.1 2.8 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 OEU19211.1 - 3.2e-05 23.8 0.1 7.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OEU19211.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Lycopene_cycl PF05834.12 OEU19212.1 - 6.5e-62 209.8 0.0 9.6e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OEU19212.1 - 3.1e-05 23.4 0.1 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OEU19212.1 - 0.0014 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU19212.1 - 0.0067 15.7 0.1 0.057 12.6 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU19212.1 - 0.047 13.9 0.1 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OEU19212.1 - 0.051 13.7 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OEU19212.1 - 0.078 12.5 0.1 0.84 9.2 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU19212.1 - 0.093 11.8 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_10 PF13460.6 OEU19213.1 - 1.1e-21 77.5 0.0 1.7e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU19213.1 - 3.4e-12 46.4 0.0 2.3e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OEU19213.1 - 8.9e-08 31.8 0.2 1.6e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OEU19213.1 - 1e-07 31.7 0.0 2e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 OEU19213.1 - 1.5e-06 27.9 0.1 6.2e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU19213.1 - 1.6e-06 28.2 0.2 5.3e-06 26.5 0.1 1.9 1 1 1 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OEU19213.1 - 5.3e-06 25.6 0.1 8.3e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OEU19213.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OEU19213.1 - 0.0092 15.2 0.1 0.017 14.2 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU19213.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Response_reg PF00072.24 OEU19214.1 - 2.6e-20 72.7 0.1 2.7e-17 63.0 0.0 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 OEU19214.1 - 2.7e-06 27.3 0.7 9.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OEU19214.1 - 4.9e-05 24.0 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.24 OEU19215.1 - 9.7e-26 90.1 0.4 3.6e-18 65.8 0.1 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 OEU19215.1 - 8e-08 32.8 0.2 2.6e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 OEU19215.1 - 3.6e-05 24.4 0.0 9.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain PK PF00224.21 OEU19216.1 - 1.8e-117 392.1 4.5 2.5e-117 391.6 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OEU19216.1 - 1.9e-22 79.7 0.6 8.6e-22 77.6 0.1 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OEU19216.1 - 3.8e-05 22.9 0.4 8.1e-05 21.9 0.3 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_3_C PF01915.22 OEU19216.1 - 0.021 14.8 0.7 0.16 11.9 0.7 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain CPSase_L_D2 PF02786.17 OEU19217.1 - 5.6e-68 228.6 0.1 1.1e-67 227.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OEU19217.1 - 1.8e-66 223.7 0.0 3.7e-66 222.7 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OEU19217.1 - 2.3e-35 121.5 0.2 2.1e-34 118.4 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OEU19217.1 - 1e-31 109.2 0.0 2.3e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OEU19217.1 - 1.7e-25 90.1 0.0 3.2e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OEU19217.1 - 8.3e-15 54.4 5.8 8.3e-15 54.4 5.8 2.7 4 0 0 4 4 4 1 Biotin-requiring enzyme ATP-grasp PF02222.22 OEU19217.1 - 1.9e-07 30.8 0.0 6.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OEU19217.1 - 2e-07 30.8 0.0 4.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OEU19217.1 - 5.9e-06 26.0 2.5 0.00057 19.7 0.3 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 OEU19217.1 - 0.00027 21.0 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 OEU19217.1 - 0.0014 17.9 0.7 1.6 7.9 0.0 2.6 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 OEU19217.1 - 0.011 16.5 1.3 7.7 7.3 0.0 2.9 2 0 0 2 2 2 0 HlyD family secretion protein ATP-grasp_4 PF13535.6 OEU19217.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain NQRA PF05896.11 OEU19217.1 - 0.23 10.9 0.8 0.42 10.0 0.8 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) UDPGP PF01704.18 OEU19218.1 - 3.6e-18 65.4 0.0 6.5e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ACP_syn_III_C PF08541.10 OEU19219.1 - 2e-40 136.8 0.1 3e-39 133.1 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 OEU19219.1 - 6e-24 83.7 0.5 2e-23 82.0 0.5 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 OEU19219.1 - 0.00011 21.7 3.6 0.00015 21.2 0.7 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OEU19219.1 - 0.0027 17.4 0.3 0.56 9.9 0.0 3.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain Chal_sti_synt_C PF02797.15 OEU19219.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 OEU19219.1 - 0.0082 15.6 0.6 0.05 13.0 0.6 2.1 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Ketoacyl-synt_C PF02801.22 OEU19219.1 - 0.041 13.9 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain E1-E2_ATPase PF00122.20 OEU19220.1 - 1e-42 145.7 2.2 1e-42 145.7 2.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OEU19220.1 - 3.5e-26 92.8 0.2 7.8e-26 91.7 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OEU19220.1 - 0.0044 16.8 0.3 0.0044 16.8 0.3 3.5 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OEU19220.1 - 0.79 10.2 4.3 37 4.9 0.0 4.0 4 0 0 4 4 4 0 Heavy-metal-associated domain DUF305 PF03713.13 OEU19221.1 - 4.8e-08 33.3 9.6 9.6e-07 29.1 2.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF305) Atrophin-1 PF03154.15 OEU19222.1 - 0.85 7.8 6.4 0.41 8.9 0.4 2.0 2 0 0 2 2 2 0 Atrophin-1 family RNA_pol_3_Rpc31 PF11705.8 OEU19223.1 - 0.0017 18.6 3.9 0.0017 18.6 3.9 2.4 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4484 PF14831.6 OEU19223.1 - 2.4 8.2 21.5 12 5.9 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4484) MRC1 PF09444.10 OEU19223.1 - 6.6 7.2 18.7 0.37 11.3 6.4 2.7 2 0 0 2 2 2 0 MRC1-like domain GFO_IDH_MocA PF01408.22 OEU19224.1 - 7.7e-25 88.1 0.3 1.6e-24 87.0 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OEU19224.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TrkA_N PF02254.18 OEU19224.1 - 0.0039 17.4 0.0 0.02 15.2 0.0 2.1 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_3 PF03447.16 OEU19224.1 - 0.025 15.2 0.0 0.046 14.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HA PF03457.14 OEU19226.1 - 5.5e-30 103.5 1.4 2.8e-15 56.4 0.2 2.2 2 0 0 2 2 2 2 Helicase associated domain DUF2661 PF10860.8 OEU19226.1 - 0.14 12.2 1.6 6.6 6.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2661) Pr_beta_C PF12465.8 OEU19226.1 - 0.15 11.5 0.8 0.32 10.4 0.8 1.5 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Ribosomal_L6e_N PF03868.15 OEU19226.1 - 0.56 10.5 3.2 3.2 8.1 1.1 2.5 2 1 1 3 3 3 0 Ribosomal protein L6, N-terminal domain Yae1_N PF09811.9 OEU19227.1 - 1.4e-07 31.1 37.7 0.95 9.2 0.2 11.3 1 1 7 8 8 8 5 Essential protein Yae1, N terminal OMP_b-brl PF13505.6 OEU19227.1 - 0.0027 17.9 0.0 6 7.0 0.0 3.9 1 1 1 2 2 2 1 Outer membrane protein beta-barrel domain Ntox25 PF15530.6 OEU19227.1 - 0.018 15.2 0.3 74 3.5 0.0 3.9 1 1 2 4 4 4 0 Bacterial toxin 25 MtrG PF04210.13 OEU19227.1 - 0.071 13.0 19.2 43 4.1 0.1 7.3 1 1 7 8 8 8 0 Tetrahydromethanopterin S-methyltransferase, subunit G MspA PF09203.11 OEU19227.1 - 0.11 12.3 6.1 93 2.8 6.1 3.3 1 1 0 1 1 1 0 MspA Rick_17kDa_Anti PF05433.15 OEU19227.1 - 0.13 12.2 34.2 2.1 8.3 1.8 6.4 1 1 6 7 7 7 0 Glycine zipper 2TM domain OpcA PF07239.11 OEU19227.1 - 0.99 9.0 9.8 65 3.1 0.1 4.6 3 2 0 4 4 4 0 Outer membrane protein OpcA Transgly_assoc PF04226.13 OEU19227.1 - 1.8 8.8 21.8 74 3.7 0.1 7.0 1 1 3 4 4 4 0 Transglycosylase associated protein SDF PF00375.18 OEU19228.1 - 1.8e-88 297.2 35.4 4e-73 246.7 25.8 2.0 2 0 0 2 2 2 2 Sodium:dicarboxylate symporter family LCIB_C_CA PF18599.1 OEU19229.1 - 5.1e-67 225.4 0.0 6.5e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SR-25 PF10500.9 OEU19229.1 - 0.61 9.6 3.2 0.87 9.1 3.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LCIB_C_CA PF18599.1 OEU19230.1 - 5.1e-67 225.4 0.0 6.2e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Tau95_N PF17682.1 OEU19233.1 - 0.064 13.4 0.7 0.064 13.4 0.7 1.8 2 0 0 2 2 2 0 Tau95 Triple barrel domain cobW PF02492.19 OEU19234.1 - 1.3e-49 168.2 0.2 1.9e-49 167.7 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU19234.1 - 1.6e-20 72.8 0.0 2.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OEU19234.1 - 0.00026 21.0 0.2 0.43 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 OEU19234.1 - 0.0096 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 OEU19234.1 - 0.03 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 OEU19234.1 - 0.043 14.1 0.1 0.23 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OEU19234.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3494 PF11999.8 OEU19235.1 - 2.1e-30 105.9 2.4 2.3e-30 105.8 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) WRNPLPNID PF15017.6 OEU19236.1 - 0.24 12.3 6.9 0.4 11.6 2.0 2.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Porph_ging PF09697.10 OEU19236.1 - 2.8 8.5 8.9 0.26 11.8 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (Porph_ging) Coilin_N PF15862.5 OEU19236.1 - 4.3 7.1 15.0 0.98 9.2 2.2 3.3 3 0 0 3 3 3 0 Coilin N-terminus IgGFc_binding PF17517.2 OEU19237.1 - 1.7e-12 47.3 0.5 1.7e-12 47.3 0.5 2.7 4 0 0 4 4 4 1 IgGFc binding protein DUF3494 PF11999.8 OEU19238.1 - 3.7e-30 105.1 15.4 1.2e-29 103.5 15.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) zf-CCHC PF00098.23 OEU19239.1 - 0.0099 15.9 2.9 0.02 14.9 2.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Totivirus_coat PF05518.11 OEU19239.1 - 1.2 7.1 4.0 1.7 6.6 4.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein DUF4604 PF15377.6 OEU19240.1 - 6.4 7.2 8.1 3.8 7.9 5.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) CDO_I PF05995.12 OEU19241.1 - 1.5e-25 89.5 0.1 1.7e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OEU19241.1 - 0.0002 20.9 0.0 0.00079 18.9 0.0 1.6 1 1 1 2 2 2 1 PCO_ADO Yop-YscD_ppl PF16693.5 OEU19241.1 - 0.0086 15.5 0.0 0.0086 15.5 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, periplasmic domain Cupin_2 PF07883.11 OEU19241.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin domain Ank_2 PF12796.7 OEU19242.1 - 3.4e-29 101.3 5.5 1.2e-12 48.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU19242.1 - 6.7e-16 58.4 1.2 1.2e-05 25.7 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU19242.1 - 1.1e-15 57.5 4.1 7.1e-08 32.6 0.2 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 OEU19242.1 - 1.3e-14 54.0 14.4 2e-14 53.4 14.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 OEU19242.1 - 1.3e-13 49.8 0.7 2.9e-05 24.1 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ion_trans_2 PF07885.16 OEU19242.1 - 6.2e-09 35.7 3.3 6.2e-09 35.7 3.3 1.9 2 0 0 2 2 2 1 Ion channel Ank PF00023.30 OEU19242.1 - 2.3e-08 34.1 0.1 8.7e-06 26.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat cNMP_binding PF00027.29 OEU19242.1 - 0.012 15.6 0.0 0.063 13.4 0.0 2.3 2 1 0 2 2 2 0 Cyclic nucleotide-binding domain SpdB PF05122.13 OEU19242.1 - 0.081 13.1 2.4 9.9 6.4 1.2 2.5 2 0 0 2 2 2 0 Mobile element transfer protein Ashwin PF15323.6 OEU19244.1 - 0.14 12.1 6.9 0.21 11.6 6.9 1.2 1 0 0 1 1 1 0 Developmental protein Spem1 PF15670.5 OEU19244.1 - 0.48 10.0 7.6 0.73 9.4 7.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Helicase_C PF00271.31 OEU19245.1 - 8.3e-18 64.8 0.0 2.5e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OEU19245.1 - 2.3e-17 62.8 0.0 6.2e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 OEU19245.1 - 1e-09 38.6 0.0 2.7e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C_4 PF13871.6 OEU19245.1 - 0.045 13.4 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue AAA_22 PF13401.6 OEU19245.1 - 0.046 14.0 0.0 0.31 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain adh_short PF00106.25 OEU19246.1 - 5.2e-34 117.4 0.0 1.1e-33 116.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU19246.1 - 7.6e-28 97.6 0.0 1.3e-25 90.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU19246.1 - 9.4e-10 38.7 1.0 1.9e-06 27.9 0.0 2.9 2 1 1 3 3 3 2 KR domain Polysacc_synt_2 PF02719.15 OEU19246.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OEU19246.1 - 0.0054 16.2 0.2 0.011 15.2 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU19246.1 - 0.032 13.7 0.2 0.099 12.1 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 OEU19246.1 - 0.081 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CbiA PF01656.23 OEU19246.1 - 0.082 13.0 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3Beta_HSD PF01073.19 OEU19246.1 - 0.09 11.8 0.2 0.34 9.9 0.2 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DcpS_C PF11969.8 OEU19247.1 - 6.4e-19 68.5 0.9 7.7e-19 68.3 0.9 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OEU19247.1 - 4.5e-10 40.1 0.9 7.3e-10 39.5 0.9 1.3 1 1 0 1 1 1 1 HIT domain zf-DNL PF05180.12 OEU19248.1 - 1.5e-18 66.4 0.6 2.3e-18 65.9 0.6 1.3 1 0 0 1 1 1 1 DNL zinc finger UPF0167 PF03691.14 OEU19248.1 - 0.0013 18.6 0.2 0.0018 18.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0167) Elf1 PF05129.13 OEU19248.1 - 0.0074 16.3 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 OEU19248.1 - 0.11 12.9 0.2 0.24 11.8 0.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar eIF-5_eIF-2B PF01873.17 OEU19249.1 - 8.4e-36 122.4 0.4 1.4e-35 121.7 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 OEU19249.1 - 0.025 15.0 0.2 0.089 13.2 0.2 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.6 OEU19249.1 - 0.075 13.1 0.3 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-ribbon DUF1415 PF07209.12 OEU19250.1 - 2.5e-39 134.7 0.0 7e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) Ank_2 PF12796.7 OEU19251.1 - 3.5e-05 24.3 0.0 0.00013 22.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) SOTI PF17079.5 OEU19251.1 - 0.15 12.5 1.3 0.41 11.1 0.1 2.2 1 1 1 2 2 2 0 Male-specific protein scotti CDT1_C PF16679.5 OEU19251.1 - 1 9.9 3.7 2.7 8.5 0.2 2.5 1 1 1 2 2 2 0 DNA replication factor Cdt1 C-terminal domain ASF1_hist_chap PF04729.13 OEU19253.1 - 2.8e-33 115.1 0.0 5.9e-33 114.0 0.0 1.5 1 1 0 1 1 1 1 ASF1 like histone chaperone NAC PF01849.18 OEU19254.1 - 4.6e-23 81.0 0.5 9.3e-23 80.0 0.5 1.5 1 0 0 1 1 1 1 NAC domain SnoaL_2 PF12680.7 OEU19256.1 - 3e-06 27.8 0.1 9.8e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 OEU19256.1 - 3e-05 24.1 0.1 5.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2 PF00096.26 OEU19256.1 - 0.0019 18.5 0.0 0.0068 16.8 0.0 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OEU19256.1 - 0.0033 18.1 0.0 0.017 15.9 0.0 2.3 1 0 0 1 1 1 1 C2H2-type zinc finger DUF4440 PF14534.6 OEU19256.1 - 0.0054 17.1 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF1348 PF07080.11 OEU19256.1 - 0.043 13.7 1.6 0.079 12.9 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) Ig_6 PF18452.1 OEU19256.1 - 3.3 7.3 0.0 3.3 7.3 0.0 3.0 4 0 0 4 4 4 0 Immunoglobulin domain Exo_endo_phos PF03372.23 OEU19257.1 - 4.5e-05 23.1 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4064 PF13273.6 OEU19259.1 - 0.0046 17.2 5.0 1.4 9.2 0.1 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF4064) Selenoprotein_S PF06936.11 OEU19259.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.7 3 0 0 3 3 3 0 Selenoprotein S (SelS) Mem_trans PF03547.18 OEU19260.1 - 0.007 14.8 1.4 0.011 14.2 1.4 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF3784 PF12650.7 OEU19260.1 - 0.033 14.4 2.1 0.033 14.4 2.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) Orf78 PF06024.12 OEU19260.1 - 0.14 12.5 1.1 0.84 10.0 0.2 2.4 2 0 0 2 2 2 0 Orf78 (ac78) PRA1 PF03208.19 OEU19260.1 - 2 8.0 9.7 0.11 12.2 4.5 1.5 2 0 0 2 2 2 0 PRA1 family protein PALP PF00291.25 OEU19261.1 - 1.3e-09 37.9 0.0 3.3e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 OEU19262.1 - 1.1e-36 126.6 0.0 1.5e-34 119.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU19262.1 - 7e-33 114.0 0.0 1.1e-30 106.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase PDDEXK_3 PF13366.6 OEU19265.1 - 8.7e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 OEU19265.1 - 0.0021 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Hjc PF01870.18 OEU19265.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.7 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF167 PF02594.16 OEU19267.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 Glyco_transf_92 PF01697.27 OEU19268.1 - 6.9e-08 32.4 7.0 6.9e-08 32.4 7.0 2.7 3 1 0 3 3 3 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OEU19268.1 - 0.00015 22.2 0.3 0.00088 19.7 0.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 CS PF04969.16 OEU19269.1 - 3.3e-07 31.2 4.0 4.2e-06 27.7 4.0 2.4 1 1 0 1 1 1 1 CS domain DEAD PF00270.29 OEU19270.1 - 3.6e-48 163.6 0.0 1.2e-47 161.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU19270.1 - 4.9e-33 113.8 0.1 5.2e-31 107.3 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU19270.1 - 0.0059 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OEU19270.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SUB1_ProdP9 PF18213.1 OEU19270.1 - 0.16 11.8 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Septin PF00735.18 OEU19271.1 - 1.7e-17 63.6 0.2 4.1e-17 62.4 0.2 1.5 1 1 0 1 1 1 1 Septin zf-MYND PF01753.18 OEU19273.1 - 2.3e-09 37.2 13.0 6.5e-09 35.7 13.0 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU19273.1 - 0.84 9.8 6.3 2.4 8.3 6.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SRP-alpha_N PF04086.13 OEU19273.1 - 1.7 8.5 9.4 4.1 7.2 9.4 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-C6H2 PF15801.5 OEU19273.1 - 2.7 8.4 9.9 6.8 7.1 9.7 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding FAD_binding_3 PF01494.19 OEU19274.1 - 1.4e-12 47.5 1.7 5.8e-06 25.8 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 OEU19274.1 - 0.009 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU19274.1 - 0.01 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU19274.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU19274.1 - 0.061 12.6 0.2 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OEU19274.1 - 0.061 12.4 0.2 1.1 8.3 0.4 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OEU19274.1 - 0.093 12.7 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OEU19274.1 - 0.097 11.7 0.3 7.7 5.4 0.2 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Met_10 PF02475.16 OEU19275.1 - 4.6e-37 127.7 0.0 4.9e-23 81.9 0.0 2.4 2 1 0 2 2 2 2 Met-10+ like-protein Mtc PF03820.17 OEU19276.1 - 2.9e-63 213.8 0.1 1.2e-34 119.8 0.0 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier IMUP PF15761.5 OEU19276.1 - 0.12 13.0 6.2 0.19 12.5 6.2 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 OEU19276.1 - 1.2 8.7 13.0 1.7 8.2 13.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Amino_oxidase PF01593.24 OEU19277.1 - 1.1e-31 110.6 0.0 1.3e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OEU19277.1 - 0.028 14.0 0.0 0.074 12.6 0.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase SymE_toxin PF08845.10 OEU19277.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system L_protein_N PF15518.6 OEU19278.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 L protein N-terminus NAPRTase_N PF17767.1 OEU19279.1 - 1.3e-23 83.8 0.0 2.6e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 OEU19279.1 - 1.6e-22 80.0 0.0 3.1e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 OEU19279.1 - 3.1e-15 56.4 0.0 3.9e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5470 PF17564.2 OEU19279.1 - 0.35 11.1 1.9 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Macoilin PF09726.9 OEU19280.1 - 0.041 12.5 3.0 0.045 12.3 3.0 1.1 1 0 0 1 1 1 0 Macoilin family Guanylate_cyc_2 PF09778.9 OEU19281.1 - 9.6e-19 67.6 13.4 6.8e-11 41.9 7.0 4.3 1 1 1 2 2 2 2 Guanylylate cyclase APAF1_C PF17908.1 OEU19281.1 - 0.0046 17.0 1.0 0.01 15.8 1.0 1.6 1 0 0 1 1 1 1 APAF-1 helical domain Peptidase_C70 PF12385.8 OEU19281.1 - 0.01 15.8 0.5 0.044 13.8 0.1 2.2 3 0 0 3 3 3 0 Papain-like cysteine protease AvrRpt2 DUF3824 PF12868.7 OEU19281.1 - 0.32 11.6 0.1 0.32 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4882 PF16223.5 OEU19282.1 - 0.056 12.7 0.2 0.079 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) LRR_1 PF00560.33 OEU19282.1 - 0.12 13.0 2.6 3.8 8.4 0.3 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat Ank_2 PF12796.7 OEU19283.1 - 0.027 15.1 0.0 0.077 13.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FAST_2 PF08368.12 OEU19283.1 - 0.039 14.7 0.1 5.7 7.8 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Fmp27_WPPW PF10359.9 OEU19284.1 - 0.0018 17.2 3.4 0.002 17.0 3.4 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain UPF0242 PF06785.11 OEU19284.1 - 0.019 15.1 1.4 0.022 14.9 1.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Miga PF10265.9 OEU19284.1 - 0.024 13.6 0.5 0.027 13.5 0.5 1.0 1 0 0 1 1 1 0 Mitoguardin EMC3_TMCO1 PF01956.16 OEU19284.1 - 0.82 9.4 4.1 1.1 9.0 4.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Lig_chan PF00060.26 OEU19285.1 - 1.5e-10 41.1 0.3 2.3e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OEU19285.1 - 7.1e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Na_Ca_ex PF01699.24 OEU19286.1 - 2.1e-35 121.9 33.4 6.1e-19 68.5 7.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Peptidase_S41 PF03572.18 OEU19288.1 - 8.8e-06 25.4 0.1 1.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S41 THF_DHG_CYH_C PF02882.19 OEU19289.1 - 1.2e-63 213.2 1.8 1.2e-63 213.2 0.6 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OEU19289.1 - 1.3e-39 135.1 1.6 2e-39 134.5 1.6 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 OEU19289.1 - 0.023 14.0 0.2 0.068 12.5 0.2 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain OCD_Mu_crystall PF02423.15 OEU19289.1 - 0.042 12.8 0.1 0.07 12.1 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF1279 PF06916.13 OEU19290.1 - 0.1 13.2 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Drc1-Sld2 PF11719.8 OEU19291.1 - 0.23 10.9 32.0 0.43 10.1 32.0 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Alpha_kinase PF02816.18 OEU19292.1 - 4e-37 128.1 0.7 5e-37 127.8 0.7 1.1 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_M78 PF06114.13 OEU19292.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain NMO PF03060.15 OEU19293.1 - 1.6e-56 192.1 1.6 3.6e-55 187.7 1.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OEU19293.1 - 3.7e-11 42.6 0.0 4e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OEU19293.1 - 0.0039 16.2 0.3 0.0083 15.2 0.3 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 OEU19293.1 - 0.02 14.1 0.7 0.04 13.1 0.1 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SidE PF12252.8 OEU19294.1 - 0.12 9.9 0.0 0.12 9.9 0.0 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein PsbU PF06514.11 OEU19295.1 - 4.2e-18 65.1 0.0 4.6e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 OEU19295.1 - 0.0096 16.2 0.0 0.022 15.0 0.0 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix motif Arrestin_N PF00339.29 OEU19296.1 - 4.8e-09 36.4 0.0 9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OEU19296.1 - 0.00055 20.4 0.0 0.0022 18.5 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain CRAL_TRIO PF00650.20 OEU19297.1 - 1.5e-11 44.3 0.1 2.3e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain EPL1 PF10513.9 OEU19297.1 - 0.14 12.5 9.6 0.82 10.0 3.9 2.3 1 1 1 2 2 2 0 Enhancer of polycomb-like DUF4175 PF13779.6 OEU19297.1 - 0.46 8.3 8.8 0.67 7.8 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.13 OEU19297.1 - 3.1 8.4 11.0 0.15 12.7 4.8 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 OEU19297.1 - 6.8 6.8 24.8 11 6.2 9.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SET PF00856.28 OEU19298.1 - 6.7e-08 33.1 0.0 3.3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 SET domain PqiA PF04403.13 OEU19299.1 - 2.7e-12 46.8 11.4 9.2e-08 32.1 4.1 2.5 2 0 0 2 2 2 2 Paraquat-inducible protein A CLP1_P PF16575.5 OEU19300.1 - 2.3e-28 99.3 0.7 2e-23 83.2 0.0 2.0 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 OEU19300.1 - 0.0022 17.7 0.4 0.0048 16.6 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OEU19300.1 - 0.004 17.5 0.2 0.0076 16.6 0.2 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 OEU19300.1 - 0.0071 16.6 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OEU19300.1 - 0.016 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OEU19300.1 - 0.025 15.0 0.0 0.031 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OEU19300.1 - 0.027 14.6 0.5 0.037 14.1 0.4 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OEU19300.1 - 0.027 15.0 0.2 0.039 14.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OEU19300.1 - 0.041 13.9 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OEU19300.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OEU19300.1 - 0.1 13.1 0.5 0.15 12.6 0.5 1.3 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 OEU19300.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OEU19300.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase DUF815 PF05673.13 OEU19300.1 - 0.18 11.0 0.5 0.34 10.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 OEU19300.1 - 0.2 11.0 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 OEU19300.1 - 0.2 12.1 0.6 0.27 11.7 0.6 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OEU19300.1 - 0.21 10.8 0.2 0.27 10.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OEU19300.1 - 0.23 11.2 0.1 0.35 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain ACT_4 PF13291.6 OEU19302.1 - 0.075 13.6 0.0 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 ACT domain ABC_membrane_2 PF06472.15 OEU19303.1 - 9.2e-55 185.9 3.8 1.2e-54 185.5 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OEU19303.1 - 2.1e-19 70.4 0.0 4.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 OEU19303.1 - 4.7e-16 59.1 3.4 2.2e-15 56.9 3.4 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_29 PF13555.6 OEU19303.1 - 2e-05 24.2 0.1 4.8e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU19303.1 - 2.4e-05 24.8 0.0 5.6e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OEU19303.1 - 0.00013 21.8 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OEU19303.1 - 0.0013 19.0 0.1 0.0097 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OEU19303.1 - 0.002 18.7 0.0 0.0098 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OEU19303.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 OEU19303.1 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 OEU19303.1 - 0.0032 17.3 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 OEU19303.1 - 0.0033 17.1 1.7 0.0033 17.1 1.7 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF815 PF05673.13 OEU19303.1 - 0.013 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 OEU19303.1 - 0.014 14.8 0.2 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU19303.1 - 0.018 15.1 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 OEU19303.1 - 0.022 14.5 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 OEU19303.1 - 0.042 13.2 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 OEU19303.1 - 0.13 11.8 0.0 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2076 PF09849.9 OEU19304.1 - 0.023 14.7 2.7 0.023 14.7 2.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1499 PF07386.11 OEU19305.1 - 3.6e-16 59.8 0.0 1.2e-15 58.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1499) CLP_protease PF00574.23 OEU19305.1 - 0.0074 16.2 0.0 0.052 13.4 0.0 2.1 2 0 0 2 2 2 1 Clp protease DUF3682 PF12446.8 OEU19305.1 - 2.4 8.6 6.4 4.7 7.7 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CBFB_NFYA PF02045.15 OEU19306.1 - 1.7e-23 83.0 8.2 1.7e-23 83.0 8.2 4.9 5 1 0 5 5 5 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Rhomboid PF01694.22 OEU19307.1 - 4.7e-06 26.7 1.2 6.1e-06 26.3 1.2 1.2 1 0 0 1 1 1 1 Rhomboid family UPF0239 PF06783.11 OEU19307.1 - 0.28 11.4 2.1 0.61 10.3 2.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) DnaJ PF00226.31 OEU19309.1 - 6.3e-12 45.4 8.5 2.1e-11 43.8 5.3 3.1 2 1 0 2 2 2 1 DnaJ domain RPE65 PF03055.15 OEU19310.1 - 7e-63 213.4 0.1 8.4e-63 213.2 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Tfb2 PF03849.14 OEU19311.1 - 1.3e-67 228.3 0.0 1.5e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OEU19311.1 - 6.1e-09 36.2 1.3 1.4e-08 35.0 1.3 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OEU19311.1 - 0.008 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BTB PF00651.31 OEU19312.1 - 1.3e-13 51.1 1.0 3.4e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 BTB/POZ domain Flavin_Reduct PF01613.18 OEU19313.1 - 2.4e-11 43.9 0.2 4e-11 43.2 0.2 1.3 1 1 0 1 1 1 1 Flavin reductase like domain Methyltransf_25 PF13649.6 OEU19314.1 - 4.6e-18 65.7 0.0 3.2e-17 63.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU19314.1 - 4.9e-17 62.4 0.0 2.5e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU19314.1 - 2.5e-11 43.4 0.0 8.6e-11 41.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU19314.1 - 9.2e-11 42.4 0.0 8.5e-10 39.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU19314.1 - 3.5e-10 39.9 0.0 5.9e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19314.1 - 3.7e-09 36.6 0.0 6.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 OEU19314.1 - 0.00019 21.3 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 OEU19314.1 - 0.0064 16.1 0.0 0.027 14.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OEU19314.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase EF-hand_5 PF13202.6 OEU19315.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.8 3 0 0 3 3 3 0 EF hand MBOAT_2 PF13813.6 OEU19316.1 - 1.8e-10 40.9 0.1 6e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family YajC PF02699.15 OEU19316.1 - 0.014 15.3 0.7 0.035 14.0 0.7 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit Ribosomal_S6 PF01250.17 OEU19317.1 - 4.1e-15 55.8 0.1 8.4e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 Tox-ART-HYE1 PF15634.6 OEU19317.1 - 0.0087 15.4 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 HYE1 signature containing ADP-ribosyltransferase Glucokinase PF02685.16 OEU19318.1 - 6.6e-20 71.3 0.0 9.3e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Glucokinase HEAT PF02985.22 OEU19319.1 - 9.7e-17 59.6 32.7 0.05 13.9 0.1 10.3 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.6 OEU19319.1 - 1.6e-11 44.4 19.5 0.0011 19.4 0.2 7.0 5 1 2 7 7 7 4 HEAT repeats PDZ PF00595.24 OEU19319.1 - 2.1e-06 28.0 0.1 5.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Cnd1 PF12717.7 OEU19319.1 - 8e-06 26.0 1.9 3.2 7.8 0.1 4.7 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 PDZ_6 PF17820.1 OEU19319.1 - 1.6e-05 24.6 0.1 4.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU19319.1 - 0.00023 21.4 0.1 0.00054 20.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Arm PF00514.23 OEU19319.1 - 0.00048 20.1 0.3 2.4 8.3 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OEU19319.1 - 0.0051 15.4 0.3 7.4 5.0 0.0 3.7 3 1 1 4 4 4 1 Adaptin N terminal region HEAT_EZ PF13513.6 OEU19319.1 - 1.9 9.1 16.4 0.74 10.4 0.2 5.8 5 2 1 6 6 6 0 HEAT-like repeat Ras PF00071.22 OEU19320.1 - 8.2e-50 168.6 0.0 1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU19320.1 - 4.4e-31 107.6 0.0 1.2e-30 106.2 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU19320.1 - 3.1e-10 39.8 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OEU19320.1 - 3.4e-05 23.9 0.0 0.0001 22.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OEU19320.1 - 0.00028 21.2 0.1 0.001 19.4 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 OEU19320.1 - 0.0016 17.8 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OEU19320.1 - 0.012 14.8 1.1 2 7.5 0.0 2.9 2 1 0 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 OEU19320.1 - 0.022 14.7 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 OEU19320.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 OEU19320.1 - 0.038 13.3 0.1 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 OEU19320.1 - 0.051 14.0 0.0 0.093 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 OEU19320.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 OEU19320.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ArgoMid PF16487.5 OEU19320.1 - 0.063 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute AAA_33 PF13671.6 OEU19320.1 - 0.098 12.8 0.2 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OEU19320.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OEU19320.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 OEU19320.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Chloroa_b-bind PF00504.21 OEU19321.1 - 5.5e-22 79.0 0.1 7.8e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HHH PF00633.23 OEU19321.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Patatin PF01734.22 OEU19322.1 - 2.4e-22 80.1 0.0 5.7e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase HAP1_N PF04849.13 OEU19322.1 - 0.0017 17.6 1.5 0.0017 17.6 1.5 2.0 2 0 0 2 2 2 1 HAP1 N-terminal conserved region YabA PF06156.13 OEU19322.1 - 0.012 16.2 0.3 0.038 14.6 0.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA SOGA PF11365.8 OEU19322.1 - 0.043 14.9 0.2 0.15 13.2 0.2 2.0 1 0 0 1 1 1 0 Protein SOGA DUF3336 PF11815.8 OEU19322.1 - 0.072 12.8 3.3 0.15 11.7 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3336) DUF4618 PF15397.6 OEU19322.1 - 0.082 12.3 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ATPase PF06745.13 OEU19322.1 - 0.14 11.5 0.3 0.98 8.7 0.1 2.1 2 0 0 2 2 2 0 KaiC JAKMIP_CC3 PF16034.5 OEU19322.1 - 0.91 9.4 6.7 0.22 11.4 1.2 2.2 2 0 0 2 2 2 0 JAKMIP CC3 domain tRNA-synt_1 PF00133.22 OEU19323.1 - 2e-213 710.0 1.4 2.6e-213 709.6 1.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OEU19323.1 - 4.6e-17 61.9 0.8 5.7e-05 22.0 0.0 4.3 3 2 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OEU19323.1 - 2.9e-06 27.3 0.1 9e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OEU19323.1 - 1.6e-05 24.4 0.0 6.1e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain YlbE PF14003.6 OEU19323.1 - 0.094 13.2 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 YlbE-like protein RhoGAP-FF1 PF16512.5 OEU19323.1 - 0.14 12.8 0.1 0.49 11.1 0.1 2.0 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Ctr PF04145.15 OEU19327.1 - 2.9e-14 53.9 17.4 6.7e-09 36.5 5.6 2.9 2 1 1 3 3 3 2 Ctr copper transporter family Sulfotransfer_3 PF13469.6 OEU19328.1 - 0.00055 20.4 0.1 0.71 10.2 0.0 3.1 1 1 2 3 3 3 3 Sulfotransferase family SOUL PF04832.12 OEU19329.1 - 1.5e-22 80.6 1.0 1.5e-22 80.6 1.0 1.7 1 1 1 2 2 2 1 SOUL heme-binding protein Dirigent PF03018.14 OEU19330.1 - 0.013 15.3 0.3 0.029 14.2 0.3 1.5 1 0 0 1 1 1 0 Dirigent-like protein SARAF PF06682.12 OEU19331.1 - 0.01 15.5 0.2 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis BatD PF13584.6 OEU19331.1 - 0.012 14.4 0.2 0.024 13.5 0.2 1.4 1 0 0 1 1 1 0 Oxygen tolerance ODV-E18 PF10717.9 OEU19331.1 - 0.019 14.8 1.5 0.037 13.9 1.5 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4436 PF14494.6 OEU19331.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Orf78 PF06024.12 OEU19331.1 - 0.025 14.9 1.8 0.025 14.9 1.8 2.3 2 1 1 3 3 3 0 Orf78 (ac78) DUF4577 PF15145.6 OEU19331.1 - 0.034 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) TMEM154 PF15102.6 OEU19331.1 - 0.044 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family SCF PF02404.15 OEU19331.1 - 0.051 12.9 0.8 0.088 12.1 0.8 1.3 1 0 0 1 1 1 0 Stem cell factor SAP PF02037.27 OEU19332.1 - 4.4e-07 29.5 2.4 4.4e-07 29.5 2.4 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 OEU19332.1 - 0.0093 15.7 3.0 0.03 14.0 3.0 1.9 1 1 0 1 1 1 1 HeH/LEM domain TFIIA PF03153.13 OEU19332.1 - 1.1 9.2 13.9 1.3 9.0 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM_like_2 PF16357.5 OEU19332.1 - 1.8 8.5 5.4 1.4 8.8 3.5 1.8 1 1 1 2 2 2 0 Putative PepSY_TM-like SYCP2_SLD PF18584.1 OEU19332.1 - 2.2 8.6 7.2 3.7 7.8 3.8 2.3 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain CAP_N PF01213.19 OEU19333.1 - 0.21 11.1 1.8 0.23 10.9 1.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4519 PF15012.6 OEU19334.1 - 1.6 8.9 8.3 3.1 8.0 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) TPR_12 PF13424.6 OEU19336.1 - 8.5e-23 80.5 0.5 1.7e-13 50.7 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU19336.1 - 2.6e-10 39.8 0.2 6.2e-07 29.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19336.1 - 4.2e-06 26.3 0.1 0.45 10.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19336.1 - 1.7e-05 24.6 2.4 0.058 13.5 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19336.1 - 0.00026 21.0 1.5 0.0088 16.2 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3682 PF12446.8 OEU19336.1 - 0.00054 20.4 9.4 0.00054 20.4 9.4 4.4 3 1 2 5 5 4 1 Protein of unknown function (DUF3682) TPR_17 PF13431.6 OEU19336.1 - 0.0022 18.3 0.0 2.4 8.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU19336.1 - 0.043 14.5 0.2 20 5.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU19336.1 - 0.052 14.2 0.1 13 6.6 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19336.1 - 0.057 13.5 0.2 3.1 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5364 PF17322.2 OEU19336.1 - 7.6 6.8 34.1 8.3 6.7 0.2 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5364) Pro_isomerase PF00160.21 OEU19337.1 - 0.00025 21.4 0.0 0.00052 20.3 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DAP10 PF07213.11 OEU19338.1 - 0.082 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein VSP PF03302.13 OEU19338.1 - 0.11 11.3 6.5 0.13 11.1 5.2 1.6 1 1 1 2 2 2 0 Giardia variant-specific surface protein 2C_adapt PF08793.10 OEU19339.1 - 0.056 13.6 0.2 1 9.6 0.0 2.9 3 0 0 3 3 3 0 2-cysteine adaptor domain Tap-RNA_bind PF09162.10 OEU19339.1 - 0.063 13.1 5.1 1.3 8.9 0.6 2.7 2 0 0 2 2 2 0 Tap, RNA-binding Tmp39 PF10271.9 OEU19340.1 - 0.005 15.9 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane protein SET PF00856.28 OEU19341.1 - 0.0069 16.8 5.8 0.012 16.0 5.8 1.5 1 1 0 1 1 1 1 SET domain V_ATPase_I PF01496.19 OEU19341.1 - 0.008 14.2 0.3 0.011 13.8 0.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RRN3 PF05327.11 OEU19341.1 - 0.16 10.5 10.0 0.2 10.1 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 OEU19341.1 - 0.27 10.6 11.8 0.33 10.3 11.8 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 OEU19341.1 - 0.28 10.9 23.4 0.68 9.6 20.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OEU19341.1 - 1.7 7.9 18.2 2.5 7.3 18.2 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OEU19341.1 - 5.3 5.1 18.9 6.3 4.9 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OEU19341.1 - 5.3 5.0 22.0 6.7 4.7 22.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sulfotransfer_1 PF00685.27 OEU19343.1 - 0.003 17.1 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain DUF4286 PF14114.6 OEU19343.1 - 0.0084 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) UPF0184 PF03670.13 OEU19343.1 - 0.046 14.1 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) HA PF03457.14 OEU19344.1 - 1.9e-56 188.2 16.9 1.7e-14 53.9 0.3 4.0 4 0 0 4 4 4 4 Helicase associated domain ELL PF10390.9 OEU19344.1 - 1.2e-06 28.3 0.0 0.032 13.7 0.0 3.7 2 1 2 4 4 4 2 RNA polymerase II elongation factor ELL DUF3836 PF12930.7 OEU19344.1 - 0.02 14.6 1.5 5.6 6.7 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF3836) Cpta_toxin PF07254.12 OEU19344.1 - 1.2 9.2 9.5 14 5.6 0.1 3.1 3 0 0 3 3 3 0 Membrane-bound toxin component of toxin-antitoxin system JmjC PF02373.22 OEU19345.1 - 7.6e-34 116.6 1.5 9.2e-34 116.3 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 OEU19345.1 - 1e-13 51.0 0.8 2.2e-13 49.9 0.8 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 OEU19345.1 - 3.6e-12 46.5 13.4 7.2e-12 45.5 13.4 1.5 1 0 0 1 1 1 1 C5HC2 zinc finger GST_N_4 PF17172.4 OEU19346.1 - 1.4e-17 64.3 0.0 2.1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OEU19346.1 - 0.0007 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 OEU19346.1 - 0.0086 16.5 0.0 0.049 14.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Npa1 PF11707.8 OEU19346.1 - 0.23 10.8 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal TLD PF07534.16 OEU19347.1 - 9.2e-27 94.0 0.0 2.2e-26 92.7 0.0 1.6 2 0 0 2 2 2 1 TLD UCR_Fe-S_N PF10399.9 OEU19348.1 - 0.00052 19.3 0.4 0.00086 18.6 0.4 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal NESP55 PF06390.12 OEU19348.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Alanine_zipper PF11839.8 OEU19349.1 - 5.9e-07 29.8 12.9 8.9e-07 29.2 12.9 1.3 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Laminin_I PF06008.14 OEU19349.1 - 0.001 18.8 10.6 0.0012 18.6 10.6 1.3 1 1 0 1 1 1 1 Laminin Domain I HEPN_AbiU2 PF18734.1 OEU19349.1 - 0.019 14.5 3.7 0.022 14.2 3.7 1.2 1 0 0 1 1 1 0 AbiU2 LAT PF15234.6 OEU19349.1 - 0.023 14.4 5.8 0.028 14.2 5.8 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells Tropomyosin PF00261.20 OEU19349.1 - 0.024 14.0 14.0 0.043 13.2 13.6 1.5 1 1 0 1 1 1 0 Tropomyosin DUF16 PF01519.16 OEU19349.1 - 0.025 15.1 2.4 0.036 14.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 OEU19349.1 - 0.026 14.6 2.5 0.033 14.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KxDL PF10241.9 OEU19349.1 - 0.034 14.4 8.0 0.25 11.6 8.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF3560 PF12083.8 OEU19349.1 - 0.04 14.0 7.3 0.04 14.0 7.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3560) V-ATPase_G_2 PF16999.5 OEU19349.1 - 0.063 13.7 12.1 0.1 13.0 12.1 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit XhlA PF10779.9 OEU19349.1 - 0.081 13.1 12.6 4.2 7.6 12.6 2.2 1 1 0 1 1 1 0 Haemolysin XhlA FapA PF03961.13 OEU19349.1 - 0.18 10.4 9.4 0.18 10.4 9.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mitofilin PF09731.9 OEU19349.1 - 0.23 10.3 15.4 0.27 10.0 15.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LegC3_N PF18654.1 OEU19349.1 - 0.27 10.4 13.4 0.45 9.7 13.4 1.4 1 1 0 1 1 1 0 LegC3 N-terminal coiled-coil domain DUF4407 PF14362.6 OEU19349.1 - 0.59 9.4 8.1 0.65 9.3 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LUC7 PF03194.15 OEU19349.1 - 0.63 9.7 9.7 0.67 9.6 9.5 1.3 1 1 0 1 1 1 0 LUC7 N_terminus BshC PF10079.9 OEU19349.1 - 0.79 8.4 9.4 0.87 8.3 9.4 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC eIF3_subunit PF08597.10 OEU19349.1 - 1.3 8.9 15.6 1.5 8.7 15.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FlaG PF03646.15 OEU19349.1 - 1.7 8.9 14.4 3 8.1 2.4 2.4 1 1 1 2 2 2 0 FlaG protein DUF1003 PF06210.11 OEU19349.1 - 3 8.0 9.5 1.4 9.1 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) WDCP PF15390.6 OEU19349.1 - 3.3 6.0 12.1 3.9 5.7 12.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Allexi_40kDa PF05549.11 OEU19349.1 - 3.3 7.1 6.4 1.7 8.1 4.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Ndc1_Nup PF09531.10 OEU19349.1 - 3.5 6.2 13.1 3.9 6.0 13.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Uds1 PF15456.6 OEU19349.1 - 3.8 7.7 16.5 7.4 6.8 16.5 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Holin_BhlA PF10960.8 OEU19349.1 - 5 7.2 7.3 70 3.5 7.3 2.2 1 1 0 1 1 1 0 BhlA holin family DUF2203 PF09969.9 OEU19349.1 - 5.1 7.8 10.4 3 8.6 8.5 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Uso1_p115_C PF04871.13 OEU19349.1 - 6.8 7.1 22.1 0.42 11.0 14.8 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pannexin_like PF12534.8 OEU19349.1 - 7.6 5.5 9.1 5.4 6.0 7.8 1.3 1 1 0 1 1 1 0 Pannexin-like TM region of LRRC8 MTBP_C PF14920.6 OEU19349.1 - 8.1 6.1 16.2 9.5 5.9 16.2 1.1 1 0 0 1 1 1 0 MDM2-binding SlyX PF04102.12 OEU19349.1 - 8.2 7.1 8.0 21 5.8 3.6 2.7 2 1 1 3 3 3 0 SlyX ERK-JNK_inhib PF15002.6 OEU19350.1 - 0.064 12.9 0.6 16 5.1 0.0 2.7 1 1 2 3 3 3 0 ERK and JNK pathways, inhibitor RskA PF10099.9 OEU19350.1 - 4.1 7.7 9.1 40 4.4 3.9 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RdDM_RDM1 PF09187.10 OEU19351.1 - 0.059 13.4 0.4 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 RNA-directed DNA methylation 1 Fzo_mitofusin PF04799.13 OEU19352.1 - 0.018 14.6 7.3 1.2 8.7 0.1 2.8 2 1 0 2 2 2 0 fzo-like conserved region ApoO PF09769.9 OEU19352.1 - 0.37 10.8 2.4 2.8 7.9 0.6 2.5 1 1 1 2 2 2 0 Apolipoprotein O Peptidase_U57 PF05582.12 OEU19352.1 - 5.6 6.1 11.1 9.8 5.3 10.9 1.5 1 1 0 1 1 1 0 YabG peptidase U57 APH PF01636.23 OEU19353.1 - 1.2e-06 28.7 0.1 2.7e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OEU19353.1 - 1.5e-06 27.8 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU19353.1 - 0.00018 20.9 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 OEU19353.1 - 0.044 13.4 0.2 0.064 12.8 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OEU19353.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Beta_helix_2 PF18835.1 OEU19354.1 - 0.023 14.4 2.0 5.1 6.9 0.1 3.8 2 1 1 3 3 3 0 Beta helix repeat of Inulin fructotransferase YadA_head PF05658.14 OEU19354.1 - 0.34 11.3 0.1 0.34 11.3 0.1 5.1 5 1 0 5 5 5 0 Head domain of trimeric autotransporter adhesin Lactococcin PF04369.13 OEU19354.1 - 1.8 8.7 7.9 37 4.5 0.0 4.8 5 1 1 6 6 6 0 Lactococcin-like family Plant_tran PF04827.14 OEU19356.1 - 2e-55 187.6 0.5 3e-55 187.0 0.5 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 OEU19356.1 - 3.7e-10 39.7 0.1 8.1e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease VHP PF02209.19 OEU19356.1 - 0.23 11.6 0.9 1.3 9.1 0.2 2.5 3 0 0 3 3 3 0 Villin headpiece domain 2OG-FeII_Oxy_3 PF13640.6 OEU19357.1 - 3.4e-18 66.3 0.0 4.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU19357.1 - 1.4e-05 25.7 0.0 2.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU19357.1 - 4.4e-05 23.9 0.0 0.00029 21.3 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sulfotransfer_2 PF03567.14 OEU19358.1 - 9.4e-11 42.1 0.1 1.2e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family ERO1 PF04137.15 OEU19359.1 - 2.6e-82 276.8 0.0 3.1e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fasciclin PF02469.22 OEU19360.1 - 8e-54 181.3 0.0 1.3e-25 90.0 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 OEU19360.1 - 0.25 11.5 2.6 0.6 10.3 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 PT PF04886.12 OEU19361.1 - 0.0042 16.6 42.6 0.075 12.6 3.7 5.1 4 1 0 4 4 4 4 PT repeat PCSK9_C1 PF18459.1 OEU19361.1 - 0.018 15.2 0.0 2.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain SAF PF08666.12 OEU19363.1 - 0.0049 17.5 0.0 3.9 8.2 0.0 2.7 2 0 0 2 2 2 2 SAF domain Glutaminase PF04960.15 OEU19364.1 - 4.9e-86 288.4 0.0 5.6e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Glutaminase bZIP_2 PF07716.15 OEU19365.1 - 3.4e-05 23.8 8.4 3.4e-05 23.8 8.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OEU19365.1 - 3.9e-05 23.7 6.4 9.4e-05 22.4 6.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 OEU19365.1 - 0.054 13.5 0.0 0.24 11.4 0.0 2.2 1 1 0 1 1 1 0 PAS fold PAS_9 PF13426.7 OEU19365.1 - 0.076 13.3 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 PAS domain Apt1 PF10351.9 OEU19367.1 - 0.023 13.6 10.6 0.24 10.2 3.1 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain SR-25 PF10500.9 OEU19367.1 - 0.2 11.2 39.2 0.12 12.0 24.4 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 OEU19367.1 - 0.38 11.1 34.6 1.8 8.9 21.2 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain Macoilin PF09726.9 OEU19367.1 - 1.3 7.5 18.3 1.7 7.1 8.0 2.2 2 0 0 2 2 2 0 Macoilin family DUF572 PF04502.13 OEU19367.1 - 3.4 7.2 12.6 7.6 6.1 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) IQ PF00612.27 OEU19372.1 - 0.00024 20.6 7.5 0.0039 16.9 0.7 3.3 3 0 0 3 3 3 2 IQ calmodulin-binding motif MttA_Hcf106 PF02416.16 OEU19372.1 - 0.035 13.4 0.4 0.08 12.3 0.4 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family PRIMA1 PF16101.5 OEU19374.1 - 2 8.5 5.7 7.5 6.6 5.7 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sugarporin_N PF11471.8 OEU19374.1 - 3.6 7.6 14.4 22 5.1 0.4 4.9 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension RNB PF00773.19 OEU19375.1 - 3.3e-36 125.3 0.2 1.2e-18 67.6 0.0 3.6 2 1 1 3 3 3 2 RNB domain PIN_2 PF10130.9 OEU19375.1 - 0.0063 16.7 0.5 0.017 15.4 0.5 1.7 1 0 0 1 1 1 1 PIN domain Pal1 PF08316.11 OEU19376.1 - 5.7 7.7 8.5 0.57 10.9 1.3 2.3 2 1 0 2 2 2 0 Pal1 cell morphology protein BET PF17035.5 OEU19377.1 - 2.3e-13 50.1 1.5 3.9e-13 49.4 1.5 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ank_2 PF12796.7 OEU19377.1 - 4.9e-07 30.2 0.0 1.8e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU19377.1 - 8.4e-07 28.8 0.0 0.16 12.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OEU19377.1 - 1.4e-05 25.5 0.1 0.00093 19.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU19377.1 - 2.9e-05 24.2 0.0 0.016 15.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Clp_N PF02861.20 OEU19377.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Lsr2 PF11774.8 OEU19377.1 - 0.11 12.7 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 Lsr2 Lant_dehydr_N PF04738.13 OEU19377.1 - 0.17 10.0 2.1 0.24 9.5 2.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus C4bp_oligo PF18453.1 OEU19377.1 - 0.2 11.9 0.2 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha TPR_2 PF07719.17 OEU19378.1 - 6.4e-06 25.9 0.2 0.29 11.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19378.1 - 9e-05 22.1 3.0 0.2 11.6 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU19378.1 - 0.0027 18.0 0.1 0.08 13.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU19378.1 - 0.0081 16.4 0.1 0.042 14.1 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF5113 PF17140.4 OEU19378.1 - 0.019 14.8 0.5 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_7 PF13176.6 OEU19378.1 - 0.13 12.4 0.0 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.9 OEU19378.1 - 0.19 11.3 5.5 0.45 10.1 5.5 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NUDIX PF00293.28 OEU19379.1 - 8.1e-08 32.4 0.0 9.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain CHCH PF06747.13 OEU19380.1 - 0.00038 20.5 1.2 0.0006 19.9 1.2 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 OEU19380.1 - 0.00054 20.2 0.7 0.00089 19.5 0.7 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 zf-CCCH PF00642.24 OEU19381.1 - 4.1e-10 39.3 17.7 1.1e-05 25.3 3.1 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OEU19381.1 - 7.8e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OEU19381.1 - 0.1 13.3 8.3 1.4 9.7 0.3 2.9 3 1 0 3 3 3 0 Torus domain zf_CCCH_4 PF18345.1 OEU19381.1 - 1.3 9.1 15.9 0.2 11.8 1.4 3.3 3 1 0 3 3 3 0 Zinc finger domain RunxI PF08504.11 OEU19382.1 - 2.2 9.1 4.9 3.2 8.5 0.0 3.3 3 1 0 3 3 3 0 Runx inhibition domain Alpha_L_fucos PF01120.17 OEU19383.1 - 1.5e-78 264.8 15.9 3.5e-50 171.4 11.2 2.2 1 1 1 2 2 2 2 Alpha-L-fucosidase Fucosidase_C PF16757.5 OEU19383.1 - 2.4e-10 40.8 0.1 3.7e-09 37.0 0.0 2.7 2 1 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain Y_phosphatase PF00102.27 OEU19383.1 - 0.057 13.0 1.2 1.6 8.2 0.3 3.2 2 1 0 2 2 2 0 Protein-tyrosine phosphatase AF-4 PF05110.13 OEU19385.1 - 0.15 10.1 25.0 0.21 9.6 25.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Neur_chan_memb PF02932.16 OEU19385.1 - 1 9.4 11.9 3.1 7.8 11.9 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NHase_alpha PF02979.16 OEU19386.1 - 1.6e-70 236.2 0.0 1.8e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Nitrile hydratase, alpha chain Frankia_peptide PF14407.6 OEU19386.1 - 0.0016 18.4 0.2 0.093 12.7 0.0 2.6 3 0 0 3 3 3 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. GlcNAc PF11397.8 OEU19387.1 - 2.4e-55 188.4 0.4 2.3e-46 158.9 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 OEU19387.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 2 Ins134_P3_kin PF05770.11 OEU19388.1 - 1.5e-10 41.0 0.1 3.5e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain TTL PF03133.15 OEU19388.1 - 0.0013 17.9 0.0 0.0018 17.5 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family PolyA_pol PF01743.20 OEU19389.1 - 1.7e-25 89.9 0.1 3.6e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 OEU19389.1 - 0.00032 20.7 0.1 0.0032 17.5 0.1 2.3 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative GXGXG PF01493.19 OEU19389.1 - 0.0045 16.6 0.1 0.0076 15.9 0.1 1.3 1 0 0 1 1 1 1 GXGXG motif PolyA_pol_RNAbd PF12627.7 OEU19389.1 - 0.18 11.6 0.0 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A AAA_16 PF13191.6 OEU19390.1 - 2e-19 70.6 0.0 4.4e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU19390.1 - 0.038 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OEU19391.1 - 2.3e-15 57.3 0.0 4.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OEU19391.1 - 6.7e-05 23.2 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OEU19391.1 - 0.0001 22.0 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU19391.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OEU19391.1 - 0.00024 21.5 0.0 0.00036 21.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OEU19391.1 - 0.00093 19.3 0.1 0.002 18.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OEU19391.1 - 0.00094 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OEU19391.1 - 0.0036 17.0 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU19391.1 - 0.0053 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OEU19391.1 - 0.0081 16.1 0.1 0.016 15.2 0.1 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 OEU19391.1 - 0.01 15.8 0.1 0.04 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OEU19391.1 - 0.015 15.7 0.1 0.086 13.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OEU19391.1 - 0.018 14.1 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 OEU19391.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OEU19391.1 - 0.05 14.1 0.2 0.083 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OEU19391.1 - 0.054 13.4 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OEU19391.1 - 0.06 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OEU19391.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OEU19391.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 OEU19391.1 - 0.24 10.6 0.7 4 6.6 0.0 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) 2OG-FeII_Oxy_3 PF13640.6 OEU19393.1 - 1.2e-16 61.4 0.1 2e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU19393.1 - 0.0014 19.1 0.2 0.0056 17.1 0.0 2.0 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily LPP20 PF02169.16 OEU19394.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.5 2 0 0 2 2 2 0 LPP20 lipoprotein Macoilin PF09726.9 OEU19394.1 - 7.3 5.0 12.5 1.2 7.6 4.6 2.1 2 0 0 2 2 2 0 Macoilin family UPF0061 PF02696.14 OEU19395.1 - 1.9e-69 234.7 0.5 8.3e-38 130.3 0.2 2.1 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family NIF PF03031.18 OEU19396.1 - 5.1e-28 97.8 0.0 1.9e-22 79.7 0.0 2.4 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase DUF5066 PF16728.5 OEU19396.1 - 0.049 13.0 0.5 0.84 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5066) Lactamase_B_2 PF12706.7 OEU19397.1 - 2.1e-15 56.8 0.0 1.5e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU19397.1 - 0.00036 20.6 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily LCAT PF02450.15 OEU19398.1 - 8.8e-43 146.9 0.0 1.3e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 OEU19398.1 - 6.3e-07 29.3 0.0 9.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OEU19398.1 - 3.8e-05 23.3 0.0 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) DUF1749 PF08538.10 OEU19398.1 - 0.00087 18.5 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) MORN PF02493.20 OEU19399.1 - 1.4e-48 160.0 36.6 6.2e-08 32.1 0.7 9.1 9 0 0 9 9 9 9 MORN repeat DUF3048_C PF17479.2 OEU19399.1 - 0.0011 19.3 6.0 1.2 9.6 0.1 4.9 2 2 4 6 6 6 2 Protein of unknown function (DUF3048) C-terminal domain GST_C_3 PF14497.6 OEU19400.1 - 8.5e-09 35.5 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU19400.1 - 0.025 14.6 0.0 0.052 13.6 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mpv17_PMP22 PF04117.12 OEU19401.1 - 1.9e-17 63.2 4.3 3.4e-17 62.4 4.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Glucos_trans_II PF14264.6 OEU19401.1 - 0.015 14.6 0.6 0.015 14.6 0.6 2.1 2 1 0 2 2 2 0 Glucosyl transferase GtrII p450 PF00067.22 OEU19402.1 - 9.3e-30 103.8 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RVT_2 PF07727.14 OEU19403.1 - 0.011 15.4 0.0 0.012 15.3 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pom PF17251.2 OEU19404.1 - 0.029 13.7 0.1 0.032 13.5 0.1 1.1 1 0 0 1 1 1 0 Protochlamydia outer membrane protein Methyltransf_9 PF08003.11 OEU19404.1 - 0.071 12.0 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ribonuc_red_sm PF00268.21 OEU19405.1 - 2.5e-109 365.0 0.2 2.9e-109 364.8 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 OEU19405.1 - 0.18 12.7 0.0 0.32 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Methyltransf_11 PF08241.12 OEU19406.1 - 1.7e-19 70.2 0.0 3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19406.1 - 1.8e-12 47.8 0.0 3.9e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19406.1 - 6.9e-12 45.5 0.0 8.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU19406.1 - 8.4e-10 38.4 0.0 3.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OEU19406.1 - 6.1e-09 35.8 0.0 7.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU19406.1 - 1.4e-06 28.9 0.0 2.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU19406.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase VirE1 PF12189.8 OEU19406.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Single-strand DNA-binding protein UPF0020 PF01170.18 OEU19407.1 - 4.6e-20 72.1 0.0 8.7e-17 61.5 0.0 2.8 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 DUF285 PF03382.14 OEU19408.1 - 2.6e-56 188.6 33.8 2.5e-34 117.6 15.9 2.0 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 Phage_tail_L PF05100.12 OEU19408.1 - 0.015 14.6 0.6 0.092 12.1 0.6 1.9 1 1 0 1 1 1 0 Phage minor tail protein L NUC194 PF08163.12 OEU19408.1 - 2.3 7.0 10.5 1.7 7.5 0.8 2.2 1 1 1 2 2 2 0 NUC194 domain DUF4564 PF15169.6 OEU19409.1 - 0.2 11.3 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) MMU163 PF17119.5 OEU19410.1 - 0.21 10.7 4.2 0.27 10.4 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Hist_deacetyl PF00850.19 OEU19411.1 - 0.092 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain DUF2207 PF09972.9 OEU19412.1 - 0.057 12.2 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3262 PF11660.8 OEU19412.1 - 0.077 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) AA_kinase PF00696.28 OEU19413.1 - 8.1e-24 84.5 1.7 5.6e-23 81.8 1.7 2.1 1 1 0 1 1 1 1 Amino acid kinase family tRNA_Me_trans PF03054.16 OEU19414.1 - 2.4e-107 358.8 0.0 2.8e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 OEU19414.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 OEU19414.1 - 0.0019 17.4 0.3 2.6 7.1 0.0 2.7 2 1 0 2 2 2 2 NAD synthase DUF179 PF02622.15 OEU19415.1 - 2.4e-13 50.4 0.0 1.9e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized ACR, COG1678 DUF4144 PF13642.6 OEU19415.1 - 0.23 12.1 2.2 13 6.5 0.6 2.6 2 0 0 2 2 2 0 protein structure with unknown function CDC45 PF02724.14 OEU19415.1 - 0.3 9.3 9.9 0.49 8.6 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4079 PF13301.6 OEU19416.1 - 0.87 9.7 5.3 1.7 8.8 4.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) PP2C PF00481.21 OEU19417.1 - 4.6e-57 193.6 0.0 5.7e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU19417.1 - 0.00023 20.9 0.0 0.0012 18.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Zip PF02535.22 OEU19418.1 - 3.9e-14 52.6 1.8 4.5e-14 52.4 1.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF285 PF03382.14 OEU19419.1 - 7.2e-45 151.7 13.5 1.7e-31 108.5 10.0 2.2 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 PT PF04886.12 OEU19419.1 - 0.11 12.1 14.7 0.58 9.8 14.7 2.1 1 1 0 1 1 1 0 PT repeat Phage_holin_3_3 PF16083.5 OEU19420.1 - 0.03 14.4 3.4 2.6 8.2 0.2 2.5 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III TMEM65 PF10507.9 OEU19420.1 - 0.035 14.0 2.1 2.2 8.3 0.4 2.8 3 0 0 3 3 3 0 Transmembrane protein 65 Sigma_reg_N PF13800.6 OEU19420.1 - 0.73 10.2 0.0 0.73 10.2 0.0 2.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal CENP-B_dimeris PF09026.10 OEU19420.1 - 1.1 9.7 12.5 0.33 11.4 0.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Efg1 PF10153.9 OEU19421.1 - 0.15 12.4 1.7 0.15 12.4 0.6 1.5 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Zip PF02535.22 OEU19423.1 - 5.4e-33 114.6 10.7 5.7e-33 114.5 10.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DHO_dh PF01180.21 OEU19424.1 - 5.5e-97 324.5 0.0 6.7e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OEU19424.1 - 0.0052 16.2 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Helo_like_N PF17111.5 OEU19424.1 - 0.12 11.7 0.1 17 4.7 0.1 2.5 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins FMN_dh PF01070.18 OEU19424.1 - 0.22 10.5 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_Phos_1 PF00300.22 OEU19425.1 - 1e-06 28.6 0.8 2.3e-05 24.2 0.8 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FHA PF00498.26 OEU19426.1 - 2.9e-18 66.0 0.0 6.5e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OEU19426.1 - 3.3e-08 33.8 0.0 7.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GerD PF17898.1 OEU19427.1 - 0.0012 18.8 16.1 0.0012 18.8 16.1 2.0 2 0 0 2 2 2 1 Spore germination GerD central core domain STI1 PF17830.1 OEU19427.1 - 0.33 10.9 16.0 4.6 7.3 1.3 3.4 1 1 2 3 3 3 0 STI1 domain T3SS_needle_F PF09392.10 OEU19427.1 - 0.39 10.9 9.8 2.1 8.6 1.6 2.6 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Presenilin PF01080.17 OEU19427.1 - 2.9 6.6 14.5 3.1 6.4 14.5 1.1 1 0 0 1 1 1 0 Presenilin CNDH2_C PF16858.5 OEU19427.1 - 4.2 7.2 20.6 5.2 6.9 20.6 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BPL_N PF09825.9 OEU19427.1 - 5.9 5.9 8.4 6.4 5.7 8.4 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Asp-B-Hydro_N PF05279.11 OEU19427.1 - 8.3 6.4 26.7 11 6.1 26.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.17 OEU19427.1 - 9.9 6.3 8.5 13 5.9 8.5 1.2 1 0 0 1 1 1 0 DDHD domain MAPEG PF01124.18 OEU19428.1 - 0.00023 21.1 0.1 0.00078 19.3 0.1 1.9 1 1 0 1 1 1 1 MAPEG family XRN_N PF03159.18 OEU19429.1 - 1.1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Proteasome PF00227.26 OEU19430.1 - 7.1e-37 126.7 0.1 1e-36 126.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit RVT_1 PF00078.27 OEU19431.1 - 2.3e-07 30.6 0.0 6.5e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU19431.1 - 0.0098 16.6 0.7 0.038 14.7 0.7 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase eIF-3c_N PF05470.12 OEU19432.1 - 3.6e-144 481.3 7.7 8.4e-144 480.1 7.7 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OEU19432.1 - 7.2e-12 45.8 0.0 1.9e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain FCH PF00611.23 OEU19432.1 - 0.048 13.9 0.3 0.17 12.2 0.3 2.0 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain AF-4 PF05110.13 OEU19432.1 - 0.094 10.8 12.0 0.15 10.1 12.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 OEU19432.1 - 0.25 9.6 10.5 0.15 10.3 2.1 2.2 2 0 0 2 2 2 0 CDC45-like protein SR-25 PF10500.9 OEU19432.1 - 1.2 8.7 20.6 0.018 14.6 12.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pro_isomerase PF00160.21 OEU19433.1 - 1.8e-06 28.3 0.6 5.2e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PRIMA1 PF16101.5 OEU19433.1 - 0.16 12.0 2.3 0.4 10.7 2.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 OEU19433.1 - 0.26 10.7 4.2 0.13 11.7 1.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OEU19433.1 - 0.47 10.5 9.0 0.5 10.4 7.2 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator Methyltransf_13 PF08421.11 OEU19434.1 - 0.029 14.6 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative zinc binding domain Cmc1 PF08583.10 OEU19434.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Topo_Zn_Ribbon PF08272.11 OEU19436.1 - 0.093 12.4 1.3 0.4 10.4 0.3 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like ApoO PF09769.9 OEU19436.1 - 0.12 12.4 0.2 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein O U3_snoRNA_assoc PF08297.11 OEU19437.1 - 0.25 12.1 2.7 0.44 11.3 1.8 1.8 2 0 0 2 2 2 0 U3 snoRNA associated Vasculin PF15337.6 OEU19437.1 - 0.51 11.2 5.6 18 6.2 0.0 2.8 2 1 1 3 3 3 0 Vascular protein family Vasculin-like 1 Med19 PF10278.9 OEU19438.1 - 0.0023 17.9 6.8 0.0032 17.4 6.8 1.3 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 TFIIA PF03153.13 OEU19438.1 - 0.01 15.8 8.1 0.011 15.7 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OEU19438.1 - 0.027 14.1 9.0 0.032 13.8 9.0 1.3 1 0 0 1 1 1 0 Spt20 family MecA PF05389.12 OEU19438.1 - 0.03 14.0 0.7 0.044 13.4 0.7 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Suf PF05843.14 OEU19438.1 - 0.23 11.4 7.7 0.29 11.1 7.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 OEU19438.1 - 3.2 6.4 4.5 3.1 6.5 4.5 1.2 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 OEU19438.1 - 7.8 6.4 5.7 55 3.6 5.7 2.0 1 1 0 1 1 1 0 N-glycosylation protein DUF2525 PF10733.9 OEU19439.1 - 0.067 13.5 0.5 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) DUF1365 PF07103.11 OEU19440.1 - 4.2e-62 210.0 1.2 4.8e-62 209.8 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF179 PF02622.15 OEU19441.1 - 9.4e-07 28.9 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 GTP_EFTU PF00009.27 OEU19442.1 - 1.4e-38 132.4 0.0 2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OEU19442.1 - 5.7e-17 62.0 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OEU19442.1 - 0.00014 22.2 0.4 0.00043 20.6 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU19442.1 - 0.00025 21.1 0.4 0.00089 19.3 0.4 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MapZ_EC1 PF18041.1 OEU19443.1 - 0.68 10.2 0.0 0.68 10.2 0.0 3.6 5 1 0 5 5 5 0 MapZ extracellular domain 1 DUF2854 PF11016.8 OEU19444.1 - 1.5e-44 151.4 0.0 1.8e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) CD20 PF04103.15 OEU19444.1 - 0.0046 17.1 0.5 0.0062 16.6 0.5 1.1 1 0 0 1 1 1 1 CD20-like family SAP PF02037.27 OEU19445.1 - 1.7e-24 85.1 5.0 2e-12 46.5 1.2 2.5 2 0 0 2 2 2 2 SAP domain HeH PF12949.7 OEU19445.1 - 2.1e-05 24.1 2.4 0.00078 19.1 0.3 3.0 2 1 0 2 2 2 1 HeH/LEM domain Telomere_Sde2_2 PF13297.6 OEU19445.1 - 0.022 14.4 0.9 0.41 10.3 0.2 2.8 2 0 0 2 2 2 0 Telomere stability C-terminal YkuI_C PF10388.9 OEU19446.1 - 0.0077 16.0 0.8 0.013 15.4 0.1 1.6 2 0 0 2 2 2 1 EAL-domain associated signalling protein domain Uso1_p115_C PF04871.13 OEU19446.1 - 0.17 12.3 12.6 0.096 13.1 5.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2478 PF10649.9 OEU19449.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) DUF3874 PF12990.7 OEU19451.1 - 0.13 12.6 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) HNF_C PF09354.10 OEU19451.1 - 0.15 13.1 0.1 0.51 11.4 0.0 1.9 2 0 0 2 2 2 0 HNF3 C-terminal domain CSD PF00313.22 OEU19453.1 - 2.8e-22 78.3 3.5 3.6e-22 78.0 3.5 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU19453.1 - 3.4e-05 23.4 1.9 5.8e-05 22.7 1.9 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain CBM39 PF15886.5 OEU19453.1 - 0.073 13.0 0.2 0.099 12.5 0.2 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Pkinase PF00069.25 OEU19454.1 - 6.8e-44 150.2 0.0 8.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU19454.1 - 7.5e-16 58.2 0.0 9.9e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 OEU19454.1 - 0.00011 21.9 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 OEU19454.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 OEU19455.1 - 1e-51 174.3 0.0 1.1e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU19455.1 - 0.029 14.1 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 OEU19455.1 - 0.03 14.6 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OEU19455.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-rbx1 PF12678.7 OEU19456.1 - 3.9e-22 78.3 2.4 7.5e-22 77.4 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OEU19456.1 - 3.8e-16 58.9 4.5 6e-16 58.3 4.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OEU19456.1 - 2.6e-10 40.5 6.9 2.3e-09 37.4 6.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU19456.1 - 3e-10 39.8 2.7 2.1e-08 33.9 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU19456.1 - 4.8e-08 32.7 2.3 9.6e-08 31.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU19456.1 - 8.1e-08 32.2 0.7 1.8e-07 31.0 0.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU19456.1 - 9.9e-07 28.6 2.1 2.3e-06 27.5 2.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU19456.1 - 3.2e-06 26.9 3.7 1.2e-05 25.1 0.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OEU19456.1 - 4.6e-06 26.4 2.7 6.2e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU19456.1 - 1.8e-05 24.4 2.2 0.00039 20.1 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OEU19456.1 - 8.7e-05 22.1 1.3 8.7e-05 22.1 1.3 2.2 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OEU19456.1 - 0.00044 20.4 4.0 0.0029 17.7 1.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OEU19456.1 - 0.0028 17.4 0.2 0.0055 16.5 0.2 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_16 PF17034.5 OEU19456.1 - 0.0033 17.6 3.4 0.01 16.1 3.4 1.9 1 1 0 1 1 1 1 Zinc-ribbon like family zf-RING_4 PF14570.6 OEU19456.1 - 0.0039 17.0 0.1 0.0039 17.0 0.1 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 OEU19456.1 - 0.01 15.9 4.2 0.033 14.2 1.7 2.5 2 1 0 2 2 2 1 Zinc-finger TerY_C PF15616.6 OEU19456.1 - 0.012 15.7 1.0 0.014 15.5 0.1 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING-like PF08746.11 OEU19456.1 - 0.015 15.6 1.3 0.015 15.6 1.3 1.8 2 0 0 2 2 2 0 RING-like domain Rtf2 PF04641.12 OEU19456.1 - 0.02 14.2 1.4 0.026 13.9 0.1 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_10 PF16685.5 OEU19456.1 - 0.054 13.6 0.7 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Baculo_RING PF05883.11 OEU19456.1 - 0.095 12.7 2.0 0.34 10.9 2.0 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 OEU19456.1 - 0.11 12.7 2.2 0.11 12.7 2.2 2.3 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 OEU19456.1 - 1.3 9.2 7.9 11 6.3 8.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain DEAD PF00270.29 OEU19458.1 - 1.3e-41 142.3 0.0 6.3e-41 140.0 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU19458.1 - 6.1e-29 100.6 0.0 3e-28 98.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU19458.1 - 8.3e-05 22.7 1.5 0.00057 19.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OEU19458.1 - 0.0058 16.0 2.7 0.0085 15.5 0.0 2.2 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.23 OEU19458.1 - 0.0061 16.6 1.1 0.0061 16.6 1.1 2.0 2 0 0 2 2 2 1 Zinc knuckle SecA_DEAD PF07517.14 OEU19458.1 - 0.065 12.5 0.3 0.17 11.2 0.3 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain SBF_like PF13593.6 OEU19458.1 - 0.21 10.8 0.0 0.43 9.8 0.0 1.4 2 0 0 2 2 2 0 SBF-like CPA transporter family (DUF4137) Nop14 PF04147.12 OEU19458.1 - 0.39 8.9 8.4 0.59 8.3 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.13 OEU19458.1 - 0.46 10.3 4.0 1 9.2 3.5 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 zf-C2H2_10 PF16588.5 OEU19458.1 - 0.49 10.2 2.9 0.39 10.5 1.1 1.8 2 0 0 2 2 2 0 C2H2 zinc-finger FAM176 PF14851.6 OEU19458.1 - 5.5 6.6 8.1 10 5.8 8.1 1.4 1 0 0 1 1 1 0 FAM176 family DUF3333 PF11812.8 OEU19459.1 - 0.22 11.7 2.5 0.41 10.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) YlqD PF11068.8 OEU19459.1 - 1 9.7 6.8 0.17 12.3 2.7 1.7 2 0 0 2 2 2 0 YlqD protein Mucin PF01456.17 OEU19460.1 - 5.7 6.9 47.3 0.094 12.7 15.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Mpv17_PMP22 PF04117.12 OEU19461.1 - 1.6e-05 25.1 0.1 3.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4534 PF15049.6 OEU19461.1 - 0.056 13.2 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) P120R PF08062.11 OEU19462.1 - 5 7.6 9.6 0.2 12.1 1.9 2.5 2 0 0 2 2 2 0 P120R (NUC006) repeat PsbP PF01789.16 OEU19463.1 - 0.01 15.9 2.4 0.02 15.1 1.3 2.0 2 0 0 2 2 2 0 PsbP OST3_OST6 PF04756.13 OEU19464.1 - 0.018 14.4 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RR_TM4-6 PF06459.12 OEU19464.1 - 0.4 10.5 9.6 0.58 9.9 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 OEU19464.1 - 2.7 5.8 11.3 2.7 5.8 10.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Thioredoxin PF00085.20 OEU19466.1 - 1.1e-26 92.8 0.1 1.6e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU19466.1 - 7.1e-07 29.5 0.1 8.4e-06 26.0 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 OEU19466.1 - 2.8e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OEU19466.1 - 4.9e-06 26.5 0.0 7.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OEU19466.1 - 4.5e-05 23.9 0.2 0.00016 22.1 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OEU19466.1 - 7.7e-05 22.8 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OEU19466.1 - 9.6e-05 22.2 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 OEU19466.1 - 0.0002 21.3 0.0 0.00027 20.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OEU19466.1 - 0.00058 19.6 0.1 0.016 14.9 0.1 2.3 1 1 1 2 2 2 1 Redoxin Thioredox_DsbH PF03190.15 OEU19466.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF953 PF06110.11 OEU19466.1 - 0.046 13.3 0.3 0.12 12.0 0.3 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DIM1 PF02966.16 OEU19466.1 - 0.14 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF2951 PF11166.8 OEU19467.1 - 0.89 9.8 6.6 6.1 7.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Sulfotransfer_1 PF00685.27 OEU19468.1 - 2.8e-11 43.4 2.4 4.4e-09 36.2 1.0 2.4 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU19468.1 - 1.8e-07 31.8 4.4 1.4e-05 25.6 0.3 3.1 3 1 0 3 3 3 2 Sulfotransferase family DUF4294 PF14127.6 OEU19468.1 - 0.01 15.7 2.2 0.024 14.6 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) DUF2385 PF09539.10 OEU19468.1 - 0.31 11.6 1.6 0.56 10.8 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) L27_N PF09060.10 OEU19469.1 - 0.0024 17.9 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 L27_N FAM104 PF15434.6 OEU19469.1 - 3.3 8.3 8.0 2 9.0 5.7 1.7 1 1 0 2 2 2 0 Family 104 UPRTase PF14681.6 OEU19471.1 - 5.3e-59 199.1 0.0 7.2e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OEU19471.1 - 0.03 13.9 0.1 0.076 12.5 0.1 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Fasciclin PF02469.22 OEU19472.1 - 1.3e-11 44.8 0.3 4.9e-10 39.7 0.3 2.2 1 1 0 1 1 1 1 Fasciclin domain PRCC PF10253.9 OEU19472.1 - 0.012 16.5 9.1 0.012 16.5 9.1 3.9 2 1 1 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting MukB PF04310.12 OEU19475.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 MukB N-terminal GREB1 PF15782.5 OEU19475.1 - 0.42 7.7 5.4 0.59 7.2 5.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ferlin_C PF16165.5 OEU19475.1 - 0.61 10.0 6.9 1.7 8.6 6.9 1.7 1 0 0 1 1 1 0 Ferlin C-terminus CDC45 PF02724.14 OEU19475.1 - 1.8 6.8 11.4 3.6 5.8 11.4 1.5 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 OEU19475.1 - 6.8 5.4 8.7 11 4.7 8.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Merozoite_SPAM PF07133.11 OEU19475.1 - 7.6 6.5 35.0 0.2 11.7 24.0 2.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) EMC3_TMCO1 PF01956.16 OEU19476.1 - 7.8 6.2 8.8 9.7 5.9 0.2 2.9 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DUF2389 PF09493.10 OEU19477.1 - 0.42 11.3 4.0 16 6.2 0.0 3.1 2 1 1 3 3 3 0 Tryptophan-rich protein (DUF2389) STI1 PF17830.1 OEU19479.1 - 0.041 13.8 0.0 0.32 11.0 0.0 2.1 1 1 0 1 1 1 0 STI1 domain CT47 PF15623.6 OEU19480.1 - 0.0022 17.9 3.1 0.0022 17.9 3.1 1.5 2 0 0 2 2 2 1 Cancer/testis gene family 47 Nop14 PF04147.12 OEU19480.1 - 0.012 13.8 4.2 0.015 13.5 4.2 1.2 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.7 OEU19480.1 - 0.023 15.3 0.2 0.071 13.7 0.1 1.8 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF2235 PF09994.9 OEU19480.1 - 0.071 12.5 0.1 0.088 12.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Cytomega_UL84 PF06284.11 OEU19480.1 - 0.12 10.8 1.6 0.13 10.7 1.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DNA_pol_phi PF04931.13 OEU19480.1 - 0.39 8.7 8.4 0.52 8.3 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OEU19480.1 - 0.49 8.6 4.5 0.6 8.3 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein LRRC37AB_C PF14914.6 OEU19480.1 - 0.5 10.3 0.0 0.5 10.3 0.0 2.6 1 1 2 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain Myc_N PF01056.18 OEU19480.1 - 1 9.2 5.8 1.6 8.6 5.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region ABC1 PF03109.16 OEU19483.1 - 9.1e-10 38.7 0.0 2.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 OEU19483.1 - 0.00092 18.9 2.1 0.0011 18.6 0.0 2.1 2 1 0 3 3 3 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 OEU19483.1 - 0.032 13.8 1.4 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OEU19483.1 - 0.036 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF755 PF05501.11 OEU19483.1 - 0.32 11.3 17.7 0.051 13.8 13.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) UPF0449 PF15136.6 OEU19484.1 - 0.14 12.6 3.5 0.6 10.6 2.2 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 MG4 PF17789.1 OEU19484.1 - 0.15 12.2 0.2 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Macroglobulin domain MG4 Desulfoferrodox PF01880.18 OEU19484.1 - 0.64 10.6 5.0 0.31 11.6 1.0 2.5 2 1 0 2 2 2 0 Desulfoferrodoxin Patatin PF01734.22 OEU19486.1 - 3.2e-10 40.6 0.0 1e-09 38.9 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase tRNA_bind PF01588.20 OEU19486.1 - 0.15 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative tRNA binding domain DUF4266 PF14086.6 OEU19487.1 - 0.018 16.0 1.0 0.038 14.9 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) YdfA_immunity PF12127.8 OEU19487.1 - 0.2 10.7 5.6 0.25 10.4 5.6 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial CRAL_TRIO PF00650.20 OEU19489.1 - 6.8e-25 87.6 0.2 8.5e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OEU19489.1 - 0.0027 17.8 0.2 0.0086 16.2 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PIG-S PF10510.9 OEU19490.1 - 0.00036 19.5 3.2 0.00036 19.5 3.2 2.5 1 1 1 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein CLN3 PF02487.17 OEU19490.1 - 0.00067 18.8 1.7 0.00067 18.8 1.7 2.1 1 1 1 2 2 2 1 CLN3 protein Otopetrin PF03189.13 OEU19490.1 - 0.043 12.6 12.8 0.15 10.8 12.8 2.0 1 1 0 1 1 1 0 Otopetrin DUF4834 PF16118.5 OEU19490.1 - 0.045 14.7 15.6 2.9 8.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) UPF0542 PF15086.6 OEU19490.1 - 0.051 13.5 0.4 0.051 13.5 0.4 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0542 RNA_pol_Rpc4 PF05132.14 OEU19490.1 - 0.1 13.0 9.5 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Androgen_recep PF02166.16 OEU19490.1 - 0.25 10.1 1.6 0.33 9.7 1.6 1.1 1 0 0 1 1 1 0 Androgen receptor Methyltransf_31 PF13847.6 OEU19492.1 - 5.3e-13 49.0 0.1 1e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19492.1 - 2.8e-09 37.5 0.0 1.1e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19492.1 - 3.7e-08 33.4 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU19492.1 - 2.2e-07 31.5 0.0 5.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU19492.1 - 2.9e-06 27.9 0.0 1.1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OEU19492.1 - 0.00018 21.1 0.0 0.00053 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OEU19492.1 - 0.0088 15.4 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OEU19492.1 - 0.036 14.1 0.1 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OEU19492.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PepSY_like PF11396.8 OEU19492.1 - 0.06 13.9 3.6 0.75 10.4 0.3 3.0 2 1 1 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like eIF3_p135 PF12807.7 OEU19492.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 PT PF04886.12 OEU19493.1 - 8.9e-08 31.5 15.9 1.8e-06 27.4 4.3 3.3 3 1 0 3 3 3 2 PT repeat Fasciclin PF02469.22 OEU19493.1 - 4e-06 27.1 0.1 1.6e-05 25.1 0.0 2.0 1 1 1 2 2 2 1 Fasciclin domain DUF2001 PF09393.10 OEU19493.1 - 0.025 14.6 1.2 0.025 14.6 1.2 2.1 2 0 0 2 2 2 0 Phage tail tube protein RAP80_UIM PF18282.1 OEU19493.1 - 0.17 11.7 0.4 24 4.8 0.1 2.5 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif SUI1 PF01253.22 OEU19494.1 - 2.6e-06 27.9 0.0 6.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 SUIM_assoc PF16619.5 OEU19494.1 - 0.0039 17.2 0.5 0.0039 17.2 0.5 4.3 4 0 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 Med6 PF04934.14 OEU19494.1 - 0.031 14.1 0.9 0.079 12.8 0.0 2.1 3 0 0 3 3 3 0 MED6 mediator sub complex component CRAL_TRIO PF00650.20 OEU19495.1 - 2.2e-10 40.5 0.1 3.8e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU19495.1 - 0.0021 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NAD_binding_8 PF13450.6 OEU19498.1 - 5e-06 26.6 0.0 1.8e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OEU19498.1 - 0.017 15.1 2.1 0.071 13.1 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding HMG_box PF00505.19 OEU19499.1 - 7e-22 77.6 25.7 6.3e-13 48.9 1.9 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU19499.1 - 4.1e-13 49.7 17.9 2.3e-09 37.7 9.1 2.5 2 1 0 2 2 2 2 HMG-box domain HrcA_DNA-bdg PF03444.15 OEU19499.1 - 0.017 14.8 1.0 0.059 13.0 0.1 2.2 2 1 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DOG1 PF14144.6 OEU19499.1 - 0.044 14.0 0.2 1.9 8.8 0.1 2.4 2 0 0 2 2 2 0 Seed dormancy control DUF3802 PF12290.8 OEU19499.1 - 0.065 13.7 0.2 0.13 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Microtub_bind PF13931.6 OEU19499.1 - 0.11 12.9 5.9 0.18 12.2 5.5 1.6 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding Condensin2nSMC PF12422.8 OEU19499.1 - 0.22 11.7 3.5 1.2 9.3 0.9 2.2 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Rhodanese_C PF12368.8 OEU19500.1 - 4.9e-11 42.8 2.2 5.1e-11 42.8 0.2 2.2 2 1 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 OEU19500.1 - 1.7e-10 41.1 0.0 4.7e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OEU19500.1 - 0.0001 22.8 3.1 0.00021 21.8 0.0 3.0 3 0 0 3 3 3 1 Rhodanese-like domain FYVE PF01363.21 OEU19500.1 - 0.017 15.3 7.2 0.045 13.9 7.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger YokU PF14122.6 OEU19500.1 - 0.084 12.9 2.7 0.24 11.4 0.2 2.5 1 1 1 2 2 2 0 YokU-like protein, putative antitoxin zf-UBR PF02207.20 OEU19500.1 - 1.6 8.9 6.5 44 4.3 6.5 2.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.7 OEU19500.1 - 3.9 7.6 6.2 6.5 6.9 2.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.12 OEU19500.1 - 6.6 7.3 14.9 1.4 9.4 1.2 3.5 2 1 1 3 3 3 0 CHY zinc finger HypA PF01155.19 OEU19500.1 - 7.6 6.6 11.3 2.5 8.2 5.6 2.6 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glyco_hydro_3 PF00933.21 OEU19501.1 - 4.4e-35 121.6 0.0 6.9e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OEU19501.1 - 1.3e-29 103.7 0.0 2e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OEU19501.1 - 0.00056 20.0 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain SET PF00856.28 OEU19502.1 - 8.3e-10 39.3 0.1 8.3e-10 39.3 0.1 2.4 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 OEU19502.1 - 1.1e-07 32.2 19.0 1.1e-07 32.2 19.0 3.2 2 1 1 3 3 3 2 CXC domain Myb_DNA-binding PF00249.31 OEU19503.1 - 2.1e-10 40.7 0.4 3e-10 40.1 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU19503.1 - 2.6e-07 30.8 1.1 3.8e-07 30.3 1.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU19503.1 - 0.0034 17.2 0.7 0.0051 16.7 0.7 1.3 1 0 0 1 1 1 1 Myb DNA-binding like VEFS-Box PF09733.9 OEU19503.1 - 0.0051 16.6 0.3 0.0051 16.6 0.3 2.4 2 1 0 2 2 2 1 VEFS-Box of polycomb protein bZIP_1 PF00170.21 OEU19504.1 - 0.0014 18.7 8.4 0.0048 17.0 8.4 2.0 1 0 0 1 1 1 1 bZIP transcription factor HNH_2 PF13391.6 OEU19505.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease WD40 PF00400.32 OEU19506.1 - 0.003 18.4 4.4 29 5.7 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Pro_isomerase PF00160.21 OEU19507.1 - 4.7e-11 43.2 0.0 6.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3467 PF11950.8 OEU19507.1 - 0.13 12.5 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) DUF1995 PF09353.10 OEU19508.1 - 5e-12 46.3 0.0 8.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) VWD PF00094.25 OEU19510.1 - 0.00089 19.6 0.3 0.0071 16.6 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain RGM_N PF06535.12 OEU19510.1 - 0.0022 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus Fungal_lectin_2 PF18647.1 OEU19510.1 - 0.12 12.8 0.8 22 5.5 0.3 2.4 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin PAN_4 PF14295.6 OEU19510.1 - 0.67 9.9 5.8 0.24 11.4 0.4 2.8 3 0 0 3 3 3 0 PAN domain RAP PF08373.10 OEU19511.1 - 0.18 11.9 3.4 0.55 10.4 0.9 2.8 2 0 0 2 2 2 0 RAP domain DSPn PF14671.6 OEU19513.1 - 3.3e-35 121.6 0.1 8.5e-28 97.6 0.0 2.7 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OEU19513.1 - 6.8e-10 38.9 0.2 3e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OEU19513.1 - 0.0044 16.6 0.1 0.0098 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TLP-20 PF06088.11 OEU19513.1 - 0.026 14.4 5.5 0.42 10.5 0.4 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pox_A32 PF04665.12 OEU19513.1 - 0.16 11.4 0.1 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein ABC2_membrane_3 PF12698.7 OEU19513.1 - 0.18 10.9 4.2 0.049 12.7 0.8 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Pinin_SDK_N PF04697.13 OEU19513.1 - 0.74 10.5 6.4 11 6.6 0.2 2.4 2 0 0 2 2 2 0 pinin/SDK conserved region PBP1_TM PF14812.6 OEU19513.1 - 7.3 7.0 7.9 8 6.9 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAF-AH_p_II PF03403.13 OEU19515.1 - 7.9e-31 106.9 7.1 6.9e-27 93.9 0.1 3.0 3 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OEU19515.1 - 2.4e-10 39.7 0.1 2.5e-09 36.4 0.0 2.4 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OEU19515.1 - 3.8e-05 22.9 0.1 0.0011 18.1 0.1 2.4 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_1 PF00561.20 OEU19515.1 - 0.00049 19.8 0.0 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU19515.1 - 0.0011 18.2 0.3 1.4 8.1 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Lipase_3 PF01764.25 OEU19515.1 - 0.041 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 OEU19515.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0060 PF02694.15 OEU19516.1 - 6.8e-31 106.7 3.7 7.5e-31 106.5 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Multi_Drug_Res PF00893.19 OEU19516.1 - 0.0045 17.6 1.8 0.0051 17.5 1.5 1.3 1 1 0 1 1 1 1 Small Multidrug Resistance protein Phage_holin_1 PF04531.13 OEU19516.1 - 0.048 14.2 0.0 0.075 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin PIN_4 PF13638.6 OEU19518.1 - 0.061 13.6 1.6 0.14 12.4 1.4 1.7 1 1 0 1 1 1 0 PIN domain APC_u14 PF16635.5 OEU19518.1 - 1.6 9.3 5.0 1.1 9.9 1.5 2.3 1 1 1 2 2 2 0 Unstructured region on APC between SAMP and APC_crr DDE_Tnp_1_7 PF13843.6 OEU19521.1 - 0.00045 19.6 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 RVT_2 PF07727.14 OEU19522.1 - 4.2e-11 43.0 0.1 1.5e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1 PF01609.21 OEU19522.1 - 0.00049 19.8 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Transposase DDE domain rve PF00665.26 OEU19522.1 - 0.015 15.5 0.0 0.054 13.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain R2K_3 PF14243.6 OEU19522.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DnaJ PF00226.31 OEU19523.1 - 6.5e-16 58.2 1.9 6.5e-16 58.2 1.9 1.9 2 0 0 2 2 2 1 DnaJ domain Glycophorin_A PF01102.18 OEU19523.1 - 0.17 12.1 0.8 2.7 8.3 1.3 2.4 2 1 0 2 2 2 0 Glycophorin A CLN3 PF02487.17 OEU19523.1 - 1.8 7.5 3.9 2.6 7.0 0.1 2.2 1 1 0 2 2 2 0 CLN3 protein PT PF04886.12 OEU19524.1 - 0.019 14.5 5.7 0.031 13.8 5.7 1.2 1 0 0 1 1 1 0 PT repeat TALPID3 PF15324.6 OEU19525.1 - 1.5 6.4 7.0 2.1 5.9 7.0 1.2 1 0 0 1 1 1 0 Hedgehog signalling target DDE_Tnp_1_7 PF13843.6 OEU19529.1 - 3.1e-09 36.6 0.6 3e-08 33.4 0.0 2.3 2 1 0 2 2 2 1 Transposase IS4 rve PF00665.26 OEU19531.1 - 0.0002 21.5 0.0 0.00039 20.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain CagZ PF09053.10 OEU19531.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 CagZ Yae1_N PF09811.9 OEU19532.1 - 0.32 10.8 4.9 0.92 9.3 1.2 3.5 2 1 0 2 2 2 0 Essential protein Yae1, N terminal Keratin_2_head PF16208.5 OEU19532.1 - 1.2 9.3 21.3 1.3 9.2 9.0 2.3 1 1 1 2 2 2 0 Keratin type II head Pro_isomerase PF00160.21 OEU19533.1 - 1.4e-05 25.4 2.6 7.3e-05 23.1 2.6 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SRP9-21 PF05486.12 OEU19533.1 - 0.1 13.0 2.4 0.22 12.0 2.4 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF3494 PF11999.8 OEU19538.1 - 3.1e-49 167.4 19.0 3.1e-49 167.4 19.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) CDC24_OB3 PF17244.2 OEU19538.1 - 0.039 13.7 0.4 0.072 12.8 0.4 1.4 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Dmrt1 PF12374.8 OEU19539.1 - 5.3 7.6 7.6 3.4 8.2 3.9 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 TPT PF03151.16 OEU19542.1 - 1.1e-14 54.5 16.4 6.8e-10 38.8 8.1 3.0 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 OEU19542.1 - 4.8e-05 23.5 31.8 7.5e-05 22.9 1.3 4.1 4 0 0 4 4 4 2 EamA-like transporter family Miga PF10265.9 OEU19542.1 - 7.8 5.3 15.8 0.23 10.4 8.1 2.1 2 0 0 2 2 2 0 Mitoguardin SLATT_5 PF18160.1 OEU19543.1 - 0.0002 20.8 0.1 0.00079 18.8 0.1 1.9 1 1 1 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 Copper-bind PF00127.20 OEU19543.1 - 0.092 13.2 0.3 3.7 8.0 0.3 2.3 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family TA0956 PF11513.8 OEU19545.1 - 0.0018 18.5 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 Thermoplasma acidophilum protein TA0956 PRIMA1 PF16101.5 OEU19545.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.7 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 Rick_17kDa_Anti PF05433.15 OEU19546.1 - 0.0025 17.7 42.2 0.0086 15.9 2.8 5.6 3 2 1 4 4 4 3 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OEU19546.1 - 0.033 14.2 33.6 0.25 11.4 8.9 5.0 1 1 3 4 4 4 0 Glycine zipper Yae1_N PF09811.9 OEU19546.1 - 1.8 8.3 23.8 12 5.7 0.5 7.0 4 3 1 5 5 5 0 Essential protein Yae1, N terminal UPF0016 PF01169.19 OEU19546.1 - 7.9 6.9 17.1 7.1 7.0 0.5 4.3 2 1 2 4 4 4 0 Uncharacterized protein family UPF0016 DUF285 PF03382.14 OEU19547.1 - 1e-134 441.7 53.7 2e-36 124.4 3.2 4.6 1 1 3 4 4 4 4 Mycoplasma protein of unknown function, DUF285 DUF2585 PF10755.9 OEU19547.1 - 0.0017 18.1 0.2 17 5.1 0.0 4.5 1 1 2 4 4 4 2 Protein of unknown function (DUF2585) DrrA_P4M PF14860.6 OEU19547.1 - 0.42 10.5 7.2 41 4.1 0.0 6.3 7 3 2 9 9 9 0 DrrA phosphatidylinositol 4-phosphate binding domain FANCI_S1 PF14675.6 OEU19547.1 - 0.67 9.5 16.1 4 7.0 0.1 7.1 8 3 2 10 10 10 0 FANCI solenoid 1 LPD14 PF18827.1 OEU19547.1 - 3.8 7.8 6.2 1.3e+02 2.8 0.0 4.8 5 2 1 6 6 6 0 Large polyvalent protein-associated domain 14 LRR_4 PF12799.7 OEU19548.1 - 5.1e-06 26.7 9.7 2.4e-05 24.6 3.2 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU19548.1 - 8.1e-05 22.3 4.8 0.0019 18.0 1.0 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 OEU19548.1 - 0.064 13.8 6.4 15 6.6 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat MRP-63 PF14978.6 OEU19548.1 - 2 9.1 6.6 0.2 12.3 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 RRN3 PF05327.11 OEU19548.1 - 3.1 6.2 15.1 2.9 6.3 5.5 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 LRR_6 PF13516.6 OEU19548.1 - 5.1 7.4 8.1 12 6.2 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Fasciclin PF02469.22 OEU19549.1 - 1.3e-18 67.5 0.0 2.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Alpha_kinase PF02816.18 OEU19550.1 - 2.2e-40 138.8 0.0 3.7e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 OEU19550.1 - 3.6e-09 37.2 0.1 1.1e-08 35.7 0.1 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OEU19550.1 - 1.8e-05 25.1 0.0 0.0001 22.6 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4258 PF14076.6 OEU19550.1 - 0.06 13.7 0.3 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) vWA-TerF-like PF10138.9 OEU19550.1 - 0.1 12.7 0.0 0.53 10.3 0.0 2.2 2 1 0 2 2 2 0 vWA found in TerF C terminus Bax1-I PF01027.20 OEU19551.1 - 1.8 8.3 11.0 0.12 12.2 5.5 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PDZ_1 PF12812.7 OEU19553.1 - 0.063 13.3 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 PDZ-like domain Ank_5 PF13857.6 OEU19554.1 - 2.8e-10 40.2 0.0 0.00011 22.4 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU19554.1 - 7e-09 36.2 0.0 1.2e-08 35.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU19554.1 - 2.5e-07 31.1 0.1 8.6e-05 23.0 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU19554.1 - 1e-06 28.6 0.0 9e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU19554.1 - 8.9e-05 22.8 0.0 0.035 14.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat LRR_8 PF13855.6 OEU19556.1 - 4.1e-08 32.9 12.5 0.00066 19.4 1.6 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU19556.1 - 8.5e-07 29.2 12.3 0.0034 17.7 1.3 4.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU19556.1 - 0.003 17.9 9.1 0.61 10.8 0.2 5.5 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU19556.1 - 0.037 14.1 2.2 0.53 10.5 0.2 3.2 2 0 0 2 2 2 0 Leucine Rich repeat Cwf_Cwc_15 PF04889.12 OEU19557.1 - 0.023 14.4 22.8 0.026 14.3 22.8 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-Q PF13094.6 OEU19557.1 - 0.17 12.1 4.0 0.2 11.9 4.0 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CNDH2_C PF16858.5 OEU19557.1 - 0.34 10.7 10.5 0.41 10.5 10.5 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FYDLN_acid PF09538.10 OEU19557.1 - 0.53 11.0 16.8 0.7 10.6 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.8 OEU19557.1 - 0.63 10.2 18.2 0.73 10.0 18.2 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 OEU19557.1 - 1.8 7.8 20.1 2.2 7.5 20.1 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OEU19557.1 - 2.8 5.9 20.1 3.2 5.7 20.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OEU19557.1 - 5.3 5.1 14.2 5.7 5.0 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OEU19557.1 - 7.6 5.9 15.0 8.6 5.7 15.0 1.1 1 0 0 1 1 1 0 SDA1 DUF1336 PF07059.12 OEU19558.1 - 1.9e-51 175.4 0.0 2.4e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) CNOT1_HEAT PF16418.5 OEU19558.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Rhodanese PF00581.20 OEU19559.1 - 0.0092 16.5 0.0 0.029 14.9 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DUF1947 PF09183.10 OEU19559.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF5305 PF17231.2 OEU19559.1 - 0.52 9.7 6.2 26 4.1 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) EF-hand_7 PF13499.6 OEU19560.1 - 0.00051 20.4 0.6 0.001 19.5 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU19560.1 - 0.0029 17.9 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 OEU19560.1 - 0.0038 16.7 0.1 0.0038 16.7 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OEU19560.1 - 0.0039 17.0 0.4 0.016 15.0 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU19560.1 - 0.0062 16.0 0.3 0.0062 16.0 0.3 2.3 2 0 0 2 2 2 1 EF hand SPAR_C PF11881.8 OEU19561.1 - 0.059 13.3 0.0 0.066 13.1 0.0 1.0 1 0 0 1 1 1 0 C-terminal domain of SPAR protein PQQ_2 PF13360.6 OEU19562.1 - 0.00013 21.7 0.2 0.16 11.5 0.0 2.8 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OEU19562.1 - 0.0014 18.4 0.0 0.73 9.9 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat Spt5_N PF11942.8 OEU19562.1 - 2.5 9.2 11.9 2.7 9.0 8.5 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF1190 PF06693.11 OEU19563.1 - 0.0065 16.9 5.6 0.78 10.1 0.2 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1190) DUF16 PF01519.16 OEU19564.1 - 1.2 9.7 4.9 1.7 9.2 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 ArfGap PF01412.18 OEU19566.1 - 7.7e-27 93.7 0.6 8.3e-27 93.6 0.6 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Galactosyl_T PF01762.21 OEU19567.1 - 9.8e-05 22.3 0.1 0.019 14.8 0.0 2.9 1 1 1 2 2 2 2 Galactosyltransferase DUF131 PF01998.17 OEU19567.1 - 2.1 8.0 4.8 3.6 7.3 1.9 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF131 SecG PF03840.14 OEU19567.1 - 3.7 7.7 6.3 1.1 9.3 0.6 2.6 1 1 1 2 2 2 0 Preprotein translocase SecG subunit PhyH PF05721.13 OEU19568.1 - 1.7e-06 28.4 0.3 4.3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Sod_Cu PF00080.20 OEU19569.1 - 0.00028 21.1 1.0 0.003 17.8 0.1 2.7 2 1 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Exostosin PF03016.15 OEU19570.1 - 6.6e-08 32.1 0.1 2.4e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Exostosin family DUF5308 PF17233.2 OEU19571.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.7 3 1 1 4 4 4 0 Family of unknown function (DUF5308) cobW PF02492.19 OEU19573.1 - 7.5e-28 97.3 0.1 1.1e-27 96.8 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OEU19573.1 - 0.0071 15.4 0.7 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OEU19573.1 - 0.0093 16.0 0.1 0.055 13.5 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 OEU19573.1 - 0.0097 16.5 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OEU19573.1 - 0.019 15.5 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 OEU19573.1 - 0.023 14.2 0.0 5.6 6.5 0.0 2.3 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OEU19573.1 - 0.03 14.7 0.0 0.04 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 OEU19573.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 OEU19573.1 - 0.066 12.4 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 OEU19573.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OEU19573.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OEU19573.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PaO PF08417.12 OEU19573.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase HEAT PF02985.22 OEU19576.1 - 0.15 12.4 9.6 13 6.3 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat Arm PF00514.23 OEU19576.1 - 0.36 11.0 4.8 15 5.8 0.1 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OEU19576.1 - 2.6 8.6 6.0 12 6.5 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat ThiD2 PF17792.1 OEU19576.1 - 3.3 8.2 6.2 0.52 10.8 0.2 2.9 3 0 0 3 3 3 0 ThiD2 family SPATA48 PF15073.6 OEU19578.1 - 0.022 15.0 0.7 0.022 15.0 0.7 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 POC1 PF10450.9 OEU19579.1 - 0.0056 15.7 0.1 0.009 15.0 0.1 1.3 1 0 0 1 1 1 1 POC1 chaperone Coleoptericin PF06286.11 OEU19579.1 - 0.12 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Coleoptericin Mem_trans PF03547.18 OEU19580.1 - 3.1e-15 55.5 1.7 2.3e-09 36.1 0.1 2.6 2 1 0 2 2 2 2 Membrane transport protein IATP PF04568.12 OEU19580.1 - 0.33 11.4 2.9 0.43 11.0 1.9 1.7 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP 7tm_3 PF00003.22 OEU19581.1 - 1.4e-10 41.3 20.6 7.6e-10 38.9 20.1 2.2 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CstA PF02554.14 OEU19581.1 - 0.0073 15.2 6.1 0.013 14.4 6.1 1.4 1 0 0 1 1 1 1 Carbon starvation protein CstA ANAPC15 PF15243.6 OEU19581.1 - 0.33 11.4 7.0 0.67 10.4 7.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 LRR19-TM PF15176.6 OEU19581.1 - 2 8.5 8.0 1.1 9.3 0.1 3.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain PT PF04886.12 OEU19582.1 - 0.63 9.6 22.4 0.27 10.8 12.5 2.2 2 0 0 2 2 2 0 PT repeat PPR_2 PF13041.6 OEU19583.1 - 1.9e-40 136.8 1.9 1.2e-06 28.6 0.1 9.9 9 1 1 10 10 10 7 PPR repeat family PPR PF01535.20 OEU19583.1 - 4.4e-33 111.2 16.3 0.00093 19.3 0.1 12.0 13 0 0 13 13 13 7 PPR repeat PPR_3 PF13812.6 OEU19583.1 - 1.5e-28 98.6 0.8 3.8e-05 23.7 0.0 7.1 7 1 0 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU19583.1 - 2.7e-27 94.2 11.7 0.00021 20.9 0.0 9.8 9 0 0 9 9 9 7 PPR repeat PPR_long PF17177.4 OEU19583.1 - 1.7e-10 40.7 0.2 0.068 12.5 0.0 5.7 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OEU19583.1 - 0.0012 19.4 0.5 5.9 7.5 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19583.1 - 0.0071 16.5 0.4 4.7 7.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Hydrolase_4 PF12146.8 OEU19586.1 - 4.6e-11 42.5 0.0 1.1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU19586.1 - 2.5e-09 38.1 0.0 4e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU19586.1 - 8.4e-09 35.4 0.0 3.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OEU19586.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Amidohydro_1 PF01979.20 OEU19588.1 - 8e-69 232.6 0.4 1.2e-68 232.0 0.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 OEU19588.1 - 6.9e-50 168.4 5.0 1.6e-49 167.2 5.0 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 OEU19588.1 - 1.5e-38 131.1 0.0 4e-38 129.7 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 OEU19588.1 - 3.1e-34 116.9 0.0 1.9e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 OEU19588.1 - 6.4e-05 22.6 0.2 0.0047 16.4 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family SAM_1 PF00536.30 OEU19591.1 - 1.1e-09 38.6 0.1 1.7e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OEU19591.1 - 1.2e-09 38.2 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_MLP1_2 PF07926.12 OEU19593.1 - 0.0006 19.9 13.8 0.0006 19.9 13.8 6.1 3 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 OEU19593.1 - 2.2 8.8 11.2 5.5 7.5 2.8 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PFK PF00365.20 OEU19594.1 - 0.0015 17.9 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Phosphofructokinase PABP PF00658.18 OEU19596.1 - 0.028 14.6 1.2 0.11 12.7 1.2 2.1 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain MRP-S32 PF10210.9 OEU19596.1 - 1.3 9.6 5.0 0.71 10.5 0.9 2.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Sod_Cu PF00080.20 OEU19597.1 - 2.3e-05 24.6 0.2 0.00011 22.4 0.2 2.1 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TbpB_B_D PF01298.18 OEU19597.1 - 0.0067 16.8 0.6 0.01 16.3 0.6 1.3 1 0 0 1 1 1 1 C-lobe and N-lobe beta barrels of Tf-binding protein B Mito_fiss_reg PF05308.11 OEU19598.1 - 2.6 8.0 9.1 1.4 8.9 7.0 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator SRP-alpha_N PF04086.13 OEU19599.1 - 0.15 12.0 4.8 0.17 11.8 4.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PT PF04886.12 OEU19599.1 - 1.1 8.9 30.4 0.037 13.6 22.1 2.8 2 2 0 2 2 2 0 PT repeat Ribosomal_60s PF00428.19 OEU19600.1 - 0.096 13.3 6.3 0.27 11.8 6.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein AI-2E_transport PF01594.16 OEU19600.1 - 0.18 10.9 3.6 0.77 8.8 0.1 2.2 2 0 0 2 2 2 0 AI-2E family transporter DUF2722 PF10846.8 OEU19601.1 - 0.049 12.6 2.4 0.053 12.5 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3246 PF11596.8 OEU19601.1 - 0.33 10.3 6.0 0.45 9.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nmad5 PF18757.1 OEU19603.1 - 0.05 13.8 1.9 0.064 13.5 0.7 1.7 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 Par3_HAL_N_term PF12053.8 OEU19603.1 - 0.1 12.8 0.4 0.51 10.6 0.0 2.2 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins zf-Tim10_DDP PF02953.15 OEU19604.1 - 2.8e-12 46.1 0.2 2.8e-12 46.1 0.2 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger MMS19_C PF12460.8 OEU19604.1 - 0.067 12.3 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal DDE_1 PF03184.19 OEU19606.1 - 7.2e-07 29.0 0.0 2.8e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PTS_EIIA_2 PF00359.22 OEU19606.1 - 0.019 14.9 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 TPR_1 PF00515.28 OEU19608.1 - 0.0017 18.1 9.0 0.0045 16.7 0.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU19608.1 - 0.15 12.4 1.9 3.3 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19608.1 - 0.21 11.8 5.0 5 7.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19608.1 - 1.5 9.2 5.6 18 5.9 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 OEU19609.1 - 0.66 8.0 6.0 0.58 8.2 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OEU19609.1 - 9.7 5.8 10.9 2 8.1 7.3 1.7 1 1 1 2 2 2 0 FAM176 family DUF4064 PF13273.6 OEU19611.1 - 0.0002 21.6 1.1 0.013 15.7 0.4 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) TMEM154 PF15102.6 OEU19611.1 - 0.037 13.9 0.2 0.037 13.9 0.2 2.3 3 0 0 3 3 3 0 TMEM154 protein family SARAF PF06682.12 OEU19611.1 - 0.043 13.5 1.5 0.41 10.2 1.5 2.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Podoplanin PF05808.11 OEU19611.1 - 0.061 13.4 1.2 2.9 8.0 0.1 2.5 2 0 0 2 2 2 0 Podoplanin Cnd1_N PF12922.7 OEU19611.1 - 0.067 13.1 0.1 1.5 8.7 0.3 2.6 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term ASFV_J13L PF05568.11 OEU19611.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4834 PF16118.5 OEU19611.1 - 0.12 13.4 8.2 5.2 8.1 0.2 3.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 OEU19611.1 - 0.14 11.8 5.8 0.45 10.2 0.1 2.8 3 0 0 3 3 3 0 FAM176 family PBP1_TM PF14812.6 OEU19611.1 - 0.41 11.1 9.6 34 4.9 9.9 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CRA PF06589.11 OEU19611.1 - 1.4 9.1 8.0 0.15 12.2 1.4 2.5 2 1 1 3 3 3 0 Circumsporozoite-related antigen (CRA) FtsX PF02687.21 OEU19611.1 - 1.7 9.2 9.8 0.84 10.1 3.2 2.4 2 1 0 2 2 2 0 FtsX-like permease family TssN PF17555.2 OEU19611.1 - 5.9 6.2 10.7 0.99 8.7 1.0 2.3 1 1 0 2 2 2 0 Type VI secretion system, TssN MFS_1 PF07690.16 OEU19612.1 - 1.3e-23 83.5 24.6 2.4e-18 66.2 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OEU19612.1 - 1.5e-08 33.7 1.4 1.5e-08 33.7 1.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.8 OEU19612.1 - 0.0008 18.2 0.1 0.0008 18.2 0.1 3.1 3 1 0 3 3 3 1 Vacuole effluxer Atg22 like Vma12 PF11712.8 OEU19612.1 - 0.02 14.9 1.8 0.11 12.6 0.2 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FSAP_sig_propep PF03032.15 OEU19612.1 - 0.27 11.3 7.9 0.77 9.8 2.5 2.6 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide Peptidase_M18 PF02127.15 OEU19615.1 - 2.5e-134 448.3 0.1 9.7e-134 446.4 0.1 1.9 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OEU19615.1 - 8.5e-06 25.0 0.1 0.055 12.5 0.0 2.3 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase DUF775 PF05603.12 OEU19615.1 - 0.12 11.9 0.5 0.21 11.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) VWA PF00092.28 OEU19616.1 - 0.0032 17.8 0.3 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Pneumo_M2 PF07380.11 OEU19617.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Pneumovirus M2 protein XRN_M PF17846.1 OEU19618.1 - 0.096 11.6 7.2 0.24 10.3 1.8 2.7 3 0 0 3 3 3 0 Xrn1 helical domain Activator_LAG-3 PF11498.8 OEU19618.1 - 0.47 9.4 55.0 0.11 11.5 47.4 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 EIIBC-GUT_N PF03612.14 OEU19618.1 - 0.63 9.8 10.8 0.052 13.3 5.3 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Spem1 PF15670.5 OEU19618.1 - 1.7 8.1 15.1 0.21 11.1 10.6 1.8 2 0 0 2 2 2 0 Spermatid maturation protein 1 FAM176 PF14851.6 OEU19618.1 - 2.9 7.5 14.4 5.9 6.5 0.1 3.0 3 0 0 3 3 3 0 FAM176 family U1snRNP70_N PF12220.8 OEU19618.1 - 3.5 8.3 15.2 7.4 7.3 9.1 3.6 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Folate_carrier PF01770.18 OEU19618.1 - 4.1 6.0 7.4 1.3 7.6 4.3 1.7 2 0 0 2 2 2 0 Reduced folate carrier Connexin PF00029.19 OEU19618.1 - 4.9 6.8 9.5 13 5.5 9.5 1.6 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 OEU19618.1 - 5.5 5.8 5.7 10 4.9 5.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) MerC PF03203.14 OEU19619.1 - 1.3e-18 67.5 11.4 3e-18 66.4 11.4 1.5 1 1 0 1 1 1 1 MerC mercury resistance protein DNA_binding_1 PF01035.20 OEU19619.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain FMN_dh PF01070.18 OEU19620.1 - 1.8e-111 372.6 0.0 2e-111 372.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 OEU19620.1 - 4.4e-09 36.2 0.1 6.3e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OEU19620.1 - 4.7e-08 32.4 5.2 1.1e-06 27.9 3.3 2.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OEU19620.1 - 3.2e-07 29.8 1.3 1.3e-05 24.5 1.3 2.2 1 1 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 OEU19620.1 - 2.3e-06 27.1 1.0 0.0052 16.0 0.0 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase His_biosynth PF00977.21 OEU19620.1 - 0.00023 20.7 0.2 0.00099 18.6 0.1 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein TMP-TENI PF02581.17 OEU19620.1 - 0.00085 18.7 0.6 0.35 10.2 0.0 2.7 3 0 0 3 3 3 2 Thiamine monophosphate synthase ThiG PF05690.14 OEU19620.1 - 0.0037 16.6 3.5 0.44 9.8 0.1 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 OEU19620.1 - 0.018 14.2 1.0 0.94 8.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF561) DUF775 PF05603.12 OEU19620.1 - 0.054 13.0 0.6 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Ribul_P_3_epim PF00834.19 OEU19620.1 - 0.091 12.1 0.6 2.8 7.3 0.2 2.1 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family Dus PF01207.17 OEU19620.1 - 0.14 11.2 0.7 1.6 7.7 0.1 2.0 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) PT PF04886.12 OEU19621.1 - 1.2e-06 28.0 11.6 2e-06 27.2 10.6 1.8 2 0 0 2 2 2 1 PT repeat Prok-TraM PF09228.10 OEU19623.1 - 0.0033 17.8 0.2 0.0049 17.2 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM Haem_bd PF14376.6 OEU19623.1 - 0.047 13.6 0.3 0.096 12.6 0.1 1.6 2 0 0 2 2 2 0 Haem-binding domain DUF5633 PF18656.1 OEU19623.1 - 0.29 11.1 2.2 5.3 7.0 0.3 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5633) ADH_zinc_N PF00107.26 OEU19624.1 - 1.3e-23 83.4 0.4 2.1e-23 82.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU19624.1 - 5.2e-23 81.0 1.5 1e-22 80.0 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OEU19624.1 - 2e-12 48.3 0.0 3.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OEU19624.1 - 6.6e-05 22.5 0.1 9.8e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 OEU19624.1 - 0.0093 16.2 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain IGFBP PF00219.18 OEU19624.1 - 0.041 14.5 0.7 0.041 14.5 0.7 2.1 2 0 0 2 2 2 0 Insulin-like growth factor binding protein Ufd2P_core PF10408.9 OEU19625.1 - 6.9e-65 219.9 0.1 8.4e-65 219.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OEU19625.1 - 1.8e-26 92.1 0.3 3.2e-26 91.3 0.3 1.4 1 0 0 1 1 1 1 U-box domain DUF948 PF06103.11 OEU19625.1 - 0.067 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Aa_trans PF01490.18 OEU19627.1 - 3.1e-17 62.4 21.7 8.8e-12 44.4 11.6 2.8 3 1 0 3 3 3 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU19627.1 - 0.00035 19.7 18.0 0.11 11.5 11.8 2.8 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family UL41A PF17591.2 OEU19627.1 - 0.52 10.5 4.1 6.8 6.9 1.7 3.0 2 0 0 2 2 2 0 Herpesvirus UL41A DUF3394 PF11874.8 OEU19628.1 - 0.029 14.1 2.6 0.034 13.8 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) RRM_1 PF00076.22 OEU19629.1 - 6.6e-17 61.1 0.0 9.9e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.13 OEU19630.1 - 0.0019 17.6 0.2 0.0025 17.2 0.2 1.2 1 0 0 1 1 1 1 LETM1-like protein NTR2 PF15458.6 OEU19630.1 - 0.019 14.5 0.4 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DHOase PF12890.7 OEU19630.1 - 0.047 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Dihydro-orotase-like FHIPEP PF00771.20 OEU19630.1 - 0.091 11.2 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family bPH_2 PF03703.14 OEU19631.1 - 4.3e-12 46.0 0.2 5.5e-12 45.7 0.2 1.1 1 0 0 1 1 1 1 Bacterial PH domain SelR PF01641.18 OEU19632.1 - 1.3e-19 70.5 5.5 4.9e-12 46.0 0.1 2.7 3 0 0 3 3 3 2 SelR domain IQ PF00612.27 OEU19632.1 - 0.0018 17.9 0.4 0.0056 16.4 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4460 PF14687.6 OEU19632.1 - 0.13 12.3 1.2 5.8 7.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4460) SBP_bac_3 PF00497.20 OEU19633.1 - 0.0012 18.3 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 TCL1_MTCP1 PF01840.17 OEU19633.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 TCL1/MTCP1 family Raftlin PF15250.6 OEU19634.1 - 4.5 5.9 16.9 0.95 8.1 13.3 1.5 1 1 1 2 2 2 0 Raftlin Trypsin PF00089.26 OEU19637.1 - 2.2e-20 73.5 0.0 2.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin Ank_2 PF12796.7 OEU19638.1 - 1.2e-12 48.3 0.1 0.00029 21.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OEU19638.1 - 6.3e-09 35.9 2.1 0.053 14.0 0.5 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OEU19638.1 - 7.6e-08 32.8 3.1 0.0083 16.7 0.2 4.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU19638.1 - 9.6e-08 32.2 1.0 0.14 12.5 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU19638.1 - 1.8e-06 27.8 3.7 1.3 9.8 0.1 4.9 6 0 0 6 6 6 3 Ankyrin repeat Hanta_G1 PF01567.16 OEU19638.1 - 0.062 12.0 0.7 0.1 11.3 0.7 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 zf-CCHC PF00098.23 OEU19639.1 - 0.00083 19.3 0.4 0.0021 18.0 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.14 OEU19639.1 - 0.018 14.7 0.0 0.08 12.6 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 OEU19639.1 - 0.024 14.6 0.7 0.083 12.9 0.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 OEU19639.1 - 0.1 12.3 1.2 0.28 10.9 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle ACT_5 PF13710.6 OEU19639.1 - 0.2 11.5 0.4 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 ACT domain Sel1 PF08238.12 OEU19642.1 - 3.5e-19 68.8 0.4 8.4e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 Sel1 repeat PhyH PF05721.13 OEU19642.1 - 7.4e-13 49.2 0.0 1.7e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 OEU19642.1 - 0.0037 17.1 0.8 1.1 9.0 0.0 2.9 3 1 1 4 4 4 2 Taurine catabolism dioxygenase TauD, TfdA family Menin PF05053.13 OEU19642.1 - 0.15 10.4 3.5 0.27 9.5 3.5 1.4 1 0 0 1 1 1 0 Menin FAD_binding_4 PF01565.23 OEU19643.1 - 3.1e-19 69.1 1.1 9.8e-11 41.6 0.8 2.3 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 OEU19643.1 - 2.2e-12 46.9 0.0 4.9e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like OB_RNB PF08206.11 OEU19643.1 - 0.038 13.7 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain PBP1_TM PF14812.6 OEU19643.1 - 0.11 12.9 0.0 0.11 12.9 0.0 4.0 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pam16 PF03656.13 OEU19643.1 - 0.12 12.4 2.1 0.3 11.1 2.1 1.6 1 0 0 1 1 1 0 Pam16 Methyltransf_32 PF13679.6 OEU19644.1 - 1.3e-09 38.3 4.8 1.3e-09 38.3 4.8 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU19644.1 - 5.6e-08 32.7 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19644.1 - 1.2e-05 26.0 0.0 4.9e-05 23.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU19644.1 - 1.9e-05 25.3 0.6 0.0006 20.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OEU19644.1 - 0.00033 20.2 0.3 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain TRM13 PF05206.14 OEU19644.1 - 0.00086 18.9 8.8 0.012 15.1 0.7 3.4 2 1 1 4 4 4 2 Methyltransferase TRM13 Methyltransf_4 PF02390.17 OEU19644.1 - 0.0011 18.4 0.2 0.0053 16.2 0.0 2.2 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 OEU19644.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU19644.1 - 0.0061 17.2 0.0 0.028 15.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OEU19644.1 - 0.018 14.1 0.0 0.034 13.1 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 OEU19645.1 - 7.1e-29 100.7 0.0 8.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RsmJ PF04378.13 OEU19645.1 - 0.23 10.7 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ 7TM_GPCR_Srt PF10321.9 OEU19646.1 - 0.037 13.0 0.2 0.073 12.0 0.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt YndJ PF14158.6 OEU19646.1 - 0.46 9.8 4.4 0.068 12.5 0.6 1.5 2 0 0 2 2 2 0 YndJ-like protein Chromate_transp PF02417.15 OEU19646.1 - 0.72 10.0 2.4 0.81 9.8 0.1 2.0 2 0 0 2 2 2 0 Chromate transporter Bac_surface_Ag PF01103.23 OEU19647.1 - 3.7e-28 99.0 1.4 5.7e-28 98.3 1.4 1.3 1 1 0 1 1 1 1 Surface antigen PAP_fibrillin PF04755.12 OEU19648.1 - 1.3e-19 70.9 0.1 9.3e-19 68.1 0.1 2.0 1 1 0 1 1 1 1 PAP_fibrillin DUF4190 PF13828.6 OEU19648.1 - 0.032 14.0 0.1 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) CTX_RstB PF07459.11 OEU19648.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 CTX phage RstB protein Flavin_Reduct PF01613.18 OEU19649.1 - 7.3e-18 65.1 0.1 1.7e-17 63.9 0.0 1.6 1 1 1 2 2 2 1 Flavin reductase like domain DEAD PF00270.29 OEU19650.1 - 1.3e-33 116.3 0.3 9.9e-33 113.4 0.3 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU19650.1 - 4.6e-23 81.7 0.1 1.8e-22 79.8 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU19650.1 - 1.5e-05 25.1 0.0 4.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU19650.1 - 0.013 15.8 0.9 0.13 12.5 0.9 2.5 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 OEU19650.1 - 0.12 11.6 1.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase FKBP_C PF00254.28 OEU19651.1 - 4e-14 52.7 0.0 5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mito_carr PF00153.27 OEU19652.1 - 3.1e-27 94.3 5.4 1.3e-14 53.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein P63C PF10546.9 OEU19652.1 - 0.088 13.4 0.4 4.6 7.9 0.0 2.8 3 0 0 3 3 3 0 P63C domain Spore_YhaL PF14147.6 OEU19653.1 - 0.043 13.5 1.1 0.14 11.9 1.1 1.8 1 0 0 1 1 1 0 Sporulation protein YhaL DUF3099 PF11298.8 OEU19653.1 - 0.93 9.7 2.5 5 7.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) CDP-OH_P_transf PF01066.21 OEU19654.1 - 1e-06 29.4 0.3 2e-06 28.5 0.3 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase RAI1 PF08652.11 OEU19655.1 - 0.042 14.0 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease CTP_transf_like PF01467.26 OEU19655.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase-like Fascin PF06268.13 OEU19656.1 - 3.4e-11 43.4 1.9 0.00059 20.0 0.1 3.9 4 0 0 4 4 4 3 Fascin domain FGF PF00167.18 OEU19656.1 - 8e-07 29.2 0.2 0.13 12.4 0.0 4.1 4 0 0 4 4 4 2 Fibroblast growth factor RicinB_lectin_2 PF14200.6 OEU19656.1 - 3.5e-05 24.5 4.3 0.012 16.4 0.1 4.1 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like BCNT PF07572.12 OEU19658.1 - 1.5e-21 76.2 5.6 1.7e-21 76.0 5.6 1.0 1 0 0 1 1 1 1 Bucentaur or craniofacial development RNA_helicase PF00910.22 OEU19658.1 - 0.039 14.3 0.1 0.042 14.2 0.1 1.0 1 0 0 1 1 1 0 RNA helicase PPR_2 PF13041.6 OEU19659.1 - 2.8e-30 104.2 6.3 2.4e-09 37.3 0.0 9.8 9 2 1 10 10 10 6 PPR repeat family PPR_1 PF12854.7 OEU19659.1 - 1.5e-22 78.9 6.4 3.3e-06 26.7 0.0 8.5 8 0 0 8 8 8 5 PPR repeat PPR PF01535.20 OEU19659.1 - 3.4e-16 58.3 21.2 0.00035 20.6 0.0 10.8 11 2 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 OEU19659.1 - 5.2e-15 55.3 15.4 0.00069 19.6 0.1 7.5 6 3 0 7 7 7 3 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU19659.1 - 1.1e-06 28.2 0.4 0.015 14.6 0.0 4.0 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_12 PF13424.6 OEU19659.1 - 0.0067 16.7 0.2 45 4.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DSBA PF01323.20 OEU19659.1 - 0.15 11.8 0.2 0.4 10.4 0.2 1.7 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TPR_8 PF13181.6 OEU19659.1 - 0.24 11.7 1.1 24 5.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RVT_1 PF00078.27 OEU19660.1 - 2.4e-06 27.2 0.0 8.2e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU19660.1 - 0.0001 23.0 6.4 0.00011 22.8 3.8 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_3 PF13456.6 OEU19660.1 - 0.051 13.4 0.0 0.22 11.3 0.0 2.1 1 0 0 1 1 1 0 Reverse transcriptase-like GRP PF07172.11 OEU19660.1 - 2.3 9.0 11.0 15 6.3 11.0 2.5 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_L12 PF00542.19 OEU19663.1 - 5.6e-24 84.3 9.5 9.2e-24 83.6 9.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Rotamase PF00639.21 OEU19664.1 - 6.5e-19 68.7 0.0 6.5e-19 68.7 0.0 2.0 2 2 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OEU19664.1 - 9e-15 55.2 0.0 1.1e-13 51.8 0.0 2.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain MCC-bdg_PDZ PF10506.9 OEU19664.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Tmemb_cc2 PF10267.9 OEU19664.1 - 0.43 9.7 3.3 0.5 9.5 3.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein UbiA PF01040.18 OEU19665.1 - 0.0013 18.1 1.5 0.0017 17.7 1.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SET PF00856.28 OEU19666.1 - 3.5e-06 27.5 0.2 0.00048 20.5 0.1 3.2 2 1 0 2 2 2 1 SET domain Ald_deCOase PF11266.8 OEU19666.1 - 0.25 11.0 0.6 6 6.5 0.0 2.2 2 0 0 2 2 2 0 Long-chain fatty aldehyde decarbonylase SOAR PF16533.5 OEU19667.1 - 0.0013 18.7 0.7 0.0013 18.7 0.7 1.6 2 0 0 2 2 2 1 STIM1 Orai1-activating region Zip PF02535.22 OEU19667.1 - 0.13 11.5 3.4 0.22 10.7 0.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Ribosomal_S8e PF01201.22 OEU19667.1 - 0.28 11.3 8.3 1.3 9.2 8.4 2.0 2 1 0 2 2 2 0 Ribosomal protein S8e COX14 PF14880.6 OEU19668.1 - 0.026 14.4 0.2 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly TPR_6 PF13174.6 OEU19671.1 - 3.2e-05 24.3 0.4 0.0027 18.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19671.1 - 0.00038 20.4 0.0 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19671.1 - 0.00093 19.1 0.1 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU19671.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU19671.1 - 0.0029 17.9 0.0 0.0068 16.7 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19671.1 - 0.0045 17.0 0.0 0.071 13.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.6 OEU19671.1 - 0.0065 16.2 0.1 0.0074 16.0 0.1 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_10 PF13374.6 OEU19671.1 - 0.0085 15.9 0.2 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU19671.1 - 0.013 16.3 0.1 0.068 14.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU19671.1 - 0.041 14.5 0.0 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 OEU19671.1 - 0.042 14.3 0.3 0.077 13.4 0.3 1.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 OEU19671.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3856 PF12968.7 OEU19671.1 - 0.051 13.6 0.1 2.4 8.2 0.0 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DUF1296 PF06972.11 OEU19671.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Ribosomal_L12 PF00542.19 OEU19672.1 - 3.4e-24 85.0 8.9 3.4e-24 85.0 8.9 2.4 3 0 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OEU19672.1 - 6.1e-07 29.0 1.3 6.8e-05 22.5 0.1 2.9 3 0 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_L12 PF00542.19 OEU19673.1 - 4.9e-25 87.7 8.9 7.4e-25 87.1 8.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Gal-3-0_sulfotr PF06990.11 OEU19674.1 - 1.2e-06 27.6 0.2 0.0014 17.6 0.0 3.0 3 0 0 3 3 3 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OEU19674.1 - 2.6e-05 24.3 0.3 0.00023 21.2 0.3 2.4 1 1 0 1 1 1 1 Sulfotransferase family DUF3446 PF11928.8 OEU19674.1 - 0.38 11.1 8.8 0.69 10.2 1.4 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain PDEase_I PF00233.19 OEU19676.1 - 0.0019 18.0 0.1 0.0058 16.4 0.1 1.9 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 OEU19677.1 - 2.6e-45 154.3 0.0 3.3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAP_fibrillin PF04755.12 OEU19678.1 - 7.8e-10 39.0 0.0 2.2e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 PAP_fibrillin DnaJ-X PF14308.6 OEU19679.1 - 5.4e-36 124.0 0.3 9.6e-36 123.2 0.3 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 OEU19679.1 - 3.1e-21 75.2 0.1 9.6e-21 73.7 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 OEU19679.1 - 1e-05 25.8 0.1 3.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OEU19679.1 - 0.13 12.0 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal DUF5349 PF17298.2 OEU19680.1 - 0.02 14.7 2.8 0.026 14.3 2.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF2967 PF11179.8 OEU19680.1 - 0.03 12.4 9.9 0.049 11.7 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Androgen_recep PF02166.16 OEU19680.1 - 0.19 10.5 7.3 0.28 10.0 7.3 1.2 1 0 0 1 1 1 0 Androgen receptor 7TM_GPCR_Srv PF10323.9 OEU19680.1 - 0.32 10.3 1.5 0.39 10.0 1.5 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Spt5_N PF11942.8 OEU19680.1 - 0.92 10.5 6.3 1.5 9.8 6.3 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal MASE1 PF05231.14 OEU19681.1 - 2.1e-05 23.8 0.7 2.8e-05 23.4 0.7 1.1 1 0 0 1 1 1 1 MASE1 Folate_carrier PF01770.18 OEU19681.1 - 0.0029 16.4 0.4 0.039 12.7 0.0 2.0 2 0 0 2 2 2 1 Reduced folate carrier DUF4834 PF16118.5 OEU19681.1 - 0.014 16.3 0.5 0.014 16.3 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Macoilin PF09726.9 OEU19681.1 - 0.075 11.6 21.6 0.098 11.2 21.6 1.1 1 0 0 1 1 1 0 Macoilin family TraT PF05818.12 OEU19681.1 - 3.5 7.3 6.0 0.69 9.6 0.5 2.1 2 1 0 2 2 2 0 Enterobacterial TraT complement resistance protein CRA PF06589.11 OEU19681.1 - 5 7.2 9.1 1.4 9.0 3.6 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) His_Phos_1 PF00300.22 OEU19682.1 - 0.00018 21.2 0.0 0.00021 21.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) tRNA-synt_2c PF01411.19 OEU19684.1 - 6.5e-200 665.3 0.0 8.5e-200 664.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OEU19684.1 - 3.1e-15 56.0 0.3 1.3e-14 53.9 0.3 2.2 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OEU19684.1 - 1.5e-09 38.3 0.8 3.6e-09 37.2 0.8 1.6 1 0 0 1 1 1 1 DHHA1 domain NOA36 PF06524.12 OEU19686.1 - 0.86 8.9 6.9 1.1 8.5 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein DHHC PF01529.20 OEU19687.1 - 1.6e-26 93.0 4.8 1.6e-26 93.0 4.8 2.7 3 1 0 3 3 3 1 DHHC palmitoyltransferase Mucin PF01456.17 OEU19687.1 - 3.2e-05 23.9 6.1 6.6e-05 22.9 6.1 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Neur_chan_memb PF02932.16 OEU19687.1 - 0.02 15.0 1.5 0.044 13.8 1.5 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S28 PF05577.12 OEU19687.1 - 0.085 11.6 7.4 0.13 11.1 7.4 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Pex14_N PF04695.13 OEU19687.1 - 0.19 12.4 5.6 0.54 10.9 4.3 2.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_4 PF12799.7 OEU19689.1 - 0.0026 18.1 5.6 0.034 14.6 0.3 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU19689.1 - 0.38 11.5 4.2 7.6 7.5 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 OEU19689.1 - 6.1 7.2 6.6 8.4 6.7 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Amastin PF07344.11 OEU19690.1 - 0.005 16.7 4.8 0.012 15.5 4.8 1.6 1 0 0 1 1 1 1 Amastin surface glycoprotein zf-C2HC5 PF06221.13 OEU19690.1 - 0.066 13.2 0.7 0.2 11.7 0.7 1.8 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SRPRB PF09439.10 OEU19691.1 - 1.7e-20 73.2 0.0 2.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OEU19691.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OEU19691.1 - 6.8e-06 25.6 0.0 9.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OEU19691.1 - 1.7e-05 24.4 0.0 5.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 OEU19691.1 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU19691.1 - 0.00014 22.1 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 OEU19691.1 - 0.00034 20.2 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OEU19691.1 - 0.00085 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_35 PF14516.6 OEU19691.1 - 0.0012 17.7 1.3 0.0088 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain Septin PF00735.18 OEU19691.1 - 0.0068 15.7 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 OEU19691.1 - 0.011 16.0 0.2 0.026 14.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OEU19691.1 - 0.012 15.6 0.8 0.17 11.7 0.0 2.6 1 1 2 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 OEU19691.1 - 0.062 13.7 0.0 0.62 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase CRAL_TRIO PF00650.20 OEU19694.1 - 4.4e-25 88.3 0.0 6.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU19694.1 - 0.0011 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBN_AB PF14075.6 OEU19694.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.6 1 1 0 1 1 1 0 Ubinuclein conserved middle domain PDZ_2 PF13180.6 OEU19694.1 - 0.031 14.6 1.1 0.23 11.8 0.3 2.2 2 0 0 2 2 2 0 PDZ domain TauD PF02668.16 OEU19695.1 - 0.008 16.0 0.0 0.062 13.1 0.0 2.1 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family NUDIX PF00293.28 OEU19696.1 - 0.003 17.6 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.21 OEU19697.1 - 6.2e-08 32.3 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SUIM_assoc PF16619.5 OEU19697.1 - 0.0075 16.3 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Lsr2 PF11774.8 OEU19697.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Lsr2 B12D PF06522.11 OEU19698.1 - 0.0004 20.1 0.9 0.00076 19.2 0.8 1.5 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3649 PF12365.8 OEU19698.1 - 1.4 8.7 7.0 3.9 7.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) UPF0524 PF15823.5 OEU19699.1 - 0.0018 17.7 2.6 0.0018 17.7 2.6 2.8 3 0 0 3 3 3 1 UPF0524 of C3orf70 Mito_carr PF00153.27 OEU19701.1 - 1.1e-34 118.2 4.3 1.5e-14 53.7 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FtsX PF02687.21 OEU19701.1 - 6.4 7.3 7.8 27 5.3 2.8 2.5 2 0 0 2 2 2 0 FtsX-like permease family TPR_19 PF14559.6 OEU19702.1 - 4.4e-06 27.1 1.4 0.057 13.9 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU19702.1 - 4.8e-05 23.9 3.9 0.0013 19.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SRP72 PF08492.12 OEU19702.1 - 0.0005 20.4 8.9 0.0005 20.4 8.9 2.8 3 0 0 3 3 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 OEU19702.1 - 0.011 15.9 5.4 6.9 7.0 0.0 4.3 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OEU19702.1 - 0.011 15.9 4.9 0.51 10.7 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF447 PF04289.12 OEU19702.1 - 0.042 13.6 1.2 0.1 12.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF447) TPR_10 PF13374.6 OEU19702.1 - 0.097 12.6 0.1 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19702.1 - 0.12 12.4 1.8 2.1 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19702.1 - 0.13 12.4 8.4 0.61 10.3 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU19702.1 - 0.14 13.1 7.9 97 4.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OEU19702.1 - 0.33 11.0 3.2 16 5.6 0.6 3.6 3 2 0 4 4 4 0 Putative TPR-like repeat TPR_6 PF13174.6 OEU19702.1 - 2.6 8.8 6.2 28 5.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Antimicrobial10 PF08105.11 OEU19703.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Metchnikowin family ADH_N_2 PF16884.5 OEU19704.1 - 2e-22 79.2 0.0 2.2e-21 75.8 0.0 2.2 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OEU19704.1 - 4.4e-15 55.8 0.1 7.8e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU19704.1 - 2.7e-09 38.2 0.0 4.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CENP-B_dimeris PF09026.10 OEU19704.1 - 0.13 12.6 6.6 0.051 14.0 2.5 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cerato-platanin PF07249.12 OEU19706.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Cerato-platanin SR-25 PF10500.9 OEU19707.1 - 0.0023 17.6 3.1 0.0034 17.0 3.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein JUPITER PF17054.5 OEU19707.1 - 0.47 9.9 7.4 0.12 11.8 3.5 1.9 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter Pyr_redox_2 PF07992.14 OEU19708.1 - 2e-33 115.9 0.0 3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU19708.1 - 1.6e-16 60.5 0.0 3.9e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU19708.1 - 1.2e-08 35.4 0.1 4.6e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU19708.1 - 4.6e-06 26.0 0.4 0.0006 19.0 0.1 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OEU19708.1 - 1.4e-05 24.5 0.0 0.00098 18.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU19708.1 - 4.3e-05 22.8 0.0 0.00023 20.4 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OEU19708.1 - 0.00011 21.1 0.4 0.00027 19.8 0.0 1.8 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OEU19708.1 - 0.013 14.8 0.1 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OEU19708.1 - 0.046 13.0 0.1 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 OEU19708.1 - 0.073 12.1 0.0 0.073 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 OEU19708.1 - 0.13 11.4 0.0 0.81 8.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 OEU19708.1 - 2.4 8.4 4.1 1.8 8.8 0.2 2.6 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 4HBT PF03061.22 OEU19709.1 - 0.00027 21.2 0.0 0.00049 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4973 PF16343.5 OEU19709.1 - 0.13 12.3 1.4 3.4 7.7 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) TMEM219 PF14940.6 OEU19709.1 - 0.19 11.3 1.4 0.6 9.6 0.1 2.2 2 1 0 2 2 2 0 Transmembrane 219 UQ_con PF00179.26 OEU19710.1 - 1.2e-11 44.4 0.0 3.4e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OEU19710.1 - 0.024 14.9 0.0 0.064 13.6 0.0 1.8 1 0 0 1 1 1 0 RWD domain GDPD PF03009.17 OEU19711.1 - 1.2e-21 77.6 0.0 4.6e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family AAA_12 PF13087.6 OEU19712.1 - 8.7e-36 123.4 0.6 3.6e-35 121.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OEU19712.1 - 8.1e-21 75.0 1.8 3e-10 40.3 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OEU19712.1 - 6.1e-07 29.4 0.0 1.3e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU19712.1 - 1.2e-06 29.0 0.0 3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OEU19712.1 - 2.4e-05 24.0 0.0 0.00074 19.1 0.0 2.8 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 OEU19712.1 - 0.0035 17.1 0.1 0.0083 15.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 OEU19712.1 - 0.0043 17.4 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 OEU19712.1 - 0.011 15.7 1.1 0.072 13.1 0.0 2.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU19712.1 - 0.033 14.5 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU19712.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain VPS28 PF03997.12 OEU19713.1 - 5.3e-59 199.1 0.7 6.1e-59 198.9 0.7 1.0 1 0 0 1 1 1 1 VPS28 protein SHOCT PF09851.9 OEU19713.1 - 0.85 9.4 6.2 9.9 6.1 0.1 3.0 3 0 0 3 3 3 0 Short C-terminal domain TspO_MBR PF03073.15 OEU19714.1 - 6.4e-07 29.5 1.7 6.4e-07 29.5 1.7 2.4 2 0 0 2 2 2 1 TspO/MBR family InaF-motif PF15018.6 OEU19714.1 - 2.9 7.9 7.7 0.47 10.4 1.5 2.6 2 0 0 2 2 2 0 TRP-interacting helix Insulin_TMD PF17870.1 OEU19716.1 - 0.049 13.7 0.1 0.072 13.2 0.1 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RRM_1 PF00076.22 OEU19717.1 - 5.6e-15 54.9 0.0 6e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OEU19717.1 - 0.0046 16.5 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 OEU19717.1 - 0.097 12.7 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 RNA binding domain CD99L2 PF12301.8 OEU19719.1 - 0.31 11.3 5.3 0.4 10.9 5.3 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 RRM_1 PF00076.22 OEU19720.1 - 5.4e-17 61.4 0.0 6e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OEU19720.1 - 0.00028 20.9 0.0 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif DUF981 PF06168.11 OEU19721.1 - 0.0078 16.2 13.9 0.013 15.4 12.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF981) DUF996 PF06195.13 OEU19721.1 - 2.7 8.3 16.8 0.35 11.1 11.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF996) SBF PF01758.16 OEU19722.1 - 3.9e-34 118.0 14.7 7.5e-34 117.1 14.7 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 OEU19722.1 - 3.8e-13 49.4 19.0 5.2e-13 49.0 19.0 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Fer4_13 PF13370.6 OEU19723.1 - 4.1e-14 52.9 2.5 5e-14 52.6 2.5 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OEU19723.1 - 1.8e-08 35.0 3.7 6.1e-08 33.3 3.7 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4 PF00037.27 OEU19723.1 - 0.002 17.9 7.6 0.0092 15.8 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 OEU19723.1 - 0.003 17.6 3.4 0.0061 16.7 3.4 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 OEU19723.1 - 0.039 14.2 0.7 0.046 13.9 0.7 1.2 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Fer4_7 PF12838.7 OEU19723.1 - 0.095 13.3 1.9 0.23 12.1 1.9 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF543 PF04418.12 OEU19724.1 - 0.065 13.2 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) PspA_IM30 PF04012.12 OEU19725.1 - 8.9e-49 166.0 22.1 1.6e-48 165.2 22.1 1.3 1 0 0 1 1 1 1 PspA/IM30 family V_ATPase_I PF01496.19 OEU19725.1 - 0.12 10.3 7.6 0.2 9.5 7.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.18 OEU19725.1 - 0.23 11.6 5.4 3.7 7.7 4.0 2.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc7 PF08317.11 OEU19725.1 - 0.59 9.0 23.9 0.34 9.7 20.3 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein Lebercilin PF15619.6 OEU19725.1 - 2.2 7.9 21.0 0.97 9.1 17.7 2.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 OEU19725.1 - 4.3 7.5 14.7 0.7 10.1 6.7 3.0 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family RIC3 PF15361.6 OEU19725.1 - 4.7 7.6 0.0 4.7 7.6 0.0 3.8 3 1 1 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 BMFP PF04380.13 OEU19725.1 - 9 6.9 13.0 0.3 11.6 0.7 3.9 3 1 1 4 4 4 0 Membrane fusogenic activity Ank_2 PF12796.7 OEU19727.1 - 1.6e-15 57.4 0.0 2.7e-06 27.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU19727.1 - 1.8e-14 52.4 2.1 0.011 16.2 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OEU19727.1 - 3.6e-13 49.3 0.7 0.0086 16.5 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OEU19727.1 - 8.5e-12 45.4 1.5 0.00015 22.2 0.2 3.8 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU19727.1 - 1.6e-08 34.6 0.0 0.0021 18.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU19729.1 - 1.5e-08 35.1 0.0 0.014 15.9 0.0 4.0 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU19729.1 - 4.4e-06 26.9 0.1 2.2 8.8 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 OEU19729.1 - 1.2e-05 25.2 7.6 18 6.3 0.0 7.4 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OEU19729.1 - 1.7e-05 25.0 0.1 1.7 9.1 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU19729.1 - 0.0021 18.6 0.0 36 5.1 0.0 5.2 5 0 0 5 5 5 0 Ankyrin repeats (many copies) DUF4422 PF14393.6 OEU19729.1 - 0.029 14.2 0.8 0.053 13.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) SSV1_ORF_D-335 PF07935.11 OEU19731.1 - 0.044 14.1 0.1 0.075 13.3 0.1 1.4 1 0 0 1 1 1 0 ORF D-335-like protein PsbU PF06514.11 OEU19732.1 - 7.4e-31 106.0 0.1 1.2e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 OEU19732.1 - 0.0056 16.9 0.0 0.0097 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF4148 PF13663.6 OEU19732.1 - 3.1 8.0 6.0 7.4 6.8 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FAD_binding_3 PF01494.19 OEU19733.1 - 1.8e-13 50.5 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Mob_synth_C PF06463.13 OEU19734.1 - 8.2e-33 113.1 0.0 1.4e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OEU19734.1 - 1.2e-27 97.3 0.0 1.9e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OEU19734.1 - 6.7e-09 36.1 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OEU19734.1 - 1.6e-06 28.2 0.1 4.9e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Oxidored_molyb PF00174.19 OEU19735.1 - 2.3e-52 177.1 0.0 3.9e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OEU19735.1 - 8.4e-43 145.7 0.6 1.5e-42 144.9 0.6 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 OEU19735.1 - 4e-30 104.1 0.0 1.2e-29 102.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OEU19735.1 - 1.1e-26 93.6 0.0 1.2e-24 87.0 0.0 3.1 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OEU19735.1 - 6.1e-22 77.6 0.4 1.7e-21 76.2 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OEU19735.1 - 1.6e-08 34.8 0.0 9e-06 25.9 0.0 3.3 2 1 1 3 3 3 1 Ferric reductase NAD binding domain EMP70 PF02990.16 OEU19738.1 - 2.4e-140 468.6 5.3 2.9e-140 468.4 5.3 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 UL41A PF17591.2 OEU19738.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.4 3 1 0 3 3 3 0 Herpesvirus UL41A GSHPx PF00255.19 OEU19739.1 - 4.1e-35 119.6 0.3 5.5e-35 119.2 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OEU19739.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Orthopox_F7 PF05813.12 OEU19740.1 - 0.61 10.2 2.6 1.5 8.9 0.7 2.5 2 0 0 2 2 2 0 Orthopoxvirus F7 protein SKG6 PF08693.10 OEU19740.1 - 1.3 8.4 3.4 2.8 7.4 3.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MAP17 PF15807.5 OEU19740.1 - 2.3 8.5 4.4 21 5.3 2.0 3.0 2 1 1 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ASC PF00858.24 OEU19741.1 - 0.00095 18.2 0.7 0.0013 17.7 0.7 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Spt20 PF12090.8 OEU19741.1 - 0.001 18.8 13.1 0.0014 18.3 13.1 1.1 1 0 0 1 1 1 1 Spt20 family XRN_M PF17846.1 OEU19741.1 - 0.0027 16.7 0.9 0.0036 16.3 0.9 1.1 1 0 0 1 1 1 1 Xrn1 helical domain Peptidase_S49_N PF08496.10 OEU19741.1 - 0.0093 16.0 0.5 0.015 15.4 0.5 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DcuC PF03606.15 OEU19741.1 - 0.013 14.0 0.6 0.013 14.0 0.6 1.8 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF2681 PF10883.8 OEU19741.1 - 0.016 15.6 5.0 0.016 15.6 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.19 OEU19741.1 - 0.06 11.3 3.1 0.092 10.6 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 OEU19741.1 - 0.06 12.4 3.3 0.08 11.9 3.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Androgen_recep PF02166.16 OEU19741.1 - 0.092 11.6 8.4 0.12 11.2 8.4 1.1 1 0 0 1 1 1 0 Androgen receptor SID-1_RNA_chan PF13965.6 OEU19741.1 - 0.13 10.6 5.2 0.015 13.8 0.9 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 OEU19741.1 - 0.16 11.9 12.7 0.22 11.5 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 OEU19741.1 - 0.32 9.9 15.0 0.49 9.3 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MCM_bind PF09739.9 OEU19741.1 - 0.37 9.2 7.8 0.5 8.8 7.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF3381 PF11861.8 OEU19741.1 - 0.41 10.4 9.1 0.65 9.8 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Cytadhesin_P30 PF07271.11 OEU19741.1 - 0.43 10.1 4.9 0.26 10.8 2.7 1.7 2 0 0 2 2 2 0 Cytadhesin P30/P32 MPM1 PF17234.2 OEU19741.1 - 0.56 10.5 8.5 0.83 9.9 8.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 FtsX PF02687.21 OEU19741.1 - 0.82 10.2 14.5 1 9.9 2.0 2.8 3 0 0 3 3 3 0 FtsX-like permease family WBP-1 PF11669.8 OEU19741.1 - 2.7 8.7 10.7 3.7 8.2 3.7 2.5 1 1 1 2 2 2 0 WW domain-binding protein 1 Med3 PF11593.8 OEU19741.1 - 5.7 6.0 15.2 7.8 5.6 15.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4748 PF15932.5 OEU19741.1 - 5.8 6.7 7.8 0.43 10.4 2.4 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4748) DUF3810 PF12725.7 OEU19741.1 - 6.5 6.0 6.1 18 4.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DoxX_2 PF13564.6 OEU19742.1 - 0.035 14.2 0.9 0.035 14.2 0.9 2.0 2 0 0 2 2 2 0 DoxX-like family DnaJ PF00226.31 OEU19743.1 - 7.6e-13 48.4 0.2 4.9e-12 45.8 0.0 2.3 3 0 0 3 3 3 1 DnaJ domain COG5 PF10392.9 OEU19744.1 - 0.029 14.5 0.2 0.073 13.2 0.2 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ABC_tran_CTD PF16326.5 OEU19744.1 - 0.03 14.6 0.6 0.11 12.8 0.6 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain V-SNARE PF05008.15 OEU19744.1 - 0.031 14.7 2.9 0.1 13.0 2.9 1.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.12 OEU19744.1 - 0.05 14.2 0.1 0.12 13.0 0.1 1.7 1 0 0 1 1 1 0 SlyX CpeT PF06206.11 OEU19745.1 - 3.2e-20 72.8 0.0 7.3e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 CpeT/CpcT family (DUF1001) Cadherin_C PF01049.17 OEU19745.1 - 0.077 13.3 0.3 0.18 12.2 0.1 1.7 2 0 0 2 2 2 0 Cadherin cytoplasmic region TPR_12 PF13424.6 OEU19746.1 - 2.7e-85 280.7 21.9 4.6e-17 62.1 0.0 8.1 4 2 5 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 OEU19746.1 - 1.3e-50 167.9 13.5 1.7e-08 34.1 0.0 11.5 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19746.1 - 9.9e-50 164.4 17.3 9.2e-05 22.1 0.0 12.0 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19746.1 - 1.1e-42 140.7 14.7 0.00035 20.5 0.0 12.0 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19746.1 - 3.6e-39 129.7 24.2 0.00047 20.2 0.1 11.9 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19746.1 - 5.8e-32 107.4 9.8 0.0079 16.1 0.0 11.2 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU19746.1 - 3.8e-18 65.9 0.6 3.1e-10 40.0 0.0 3.6 1 1 3 4 4 4 3 MalT-like TPR region TPR_14 PF13428.6 OEU19746.1 - 2.7e-14 52.6 0.0 3.6 8.7 0.0 10.1 9 2 2 11 11 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU19746.1 - 1.9e-13 49.9 11.4 0.6 9.8 0.0 9.9 10 0 0 10 10 10 3 TPR repeat TPR_6 PF13174.6 OEU19746.1 - 9.4e-10 38.5 7.8 9.6 7.1 0.0 9.8 11 0 0 11 11 10 0 Tetratricopeptide repeat SNAP PF14938.6 OEU19746.1 - 2.4e-07 30.5 3.6 0.011 15.2 0.1 4.7 3 2 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 OEU19746.1 - 6.8e-07 29.8 0.0 0.5 11.1 0.0 6.7 7 1 0 7 7 6 1 Tetratricopeptide repeat SPO22 PF08631.10 OEU19746.1 - 1.6e-06 27.9 10.5 0.00064 19.3 0.3 5.2 3 3 2 5 5 5 1 Meiosis protein SPO22/ZIP4 like SHNi-TPR PF10516.9 OEU19746.1 - 2.4e-05 23.7 0.6 0.0024 17.3 0.0 4.3 6 0 0 6 6 6 1 SHNi-TPR ANAPC3 PF12895.7 OEU19746.1 - 3.2e-05 24.1 12.1 4.1 7.7 0.0 6.4 4 3 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OEU19746.1 - 6.4e-05 23.0 6.7 70 4.2 0.0 8.8 10 2 0 10 10 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU19746.1 - 0.00013 22.4 1.0 1.6 9.3 0.4 5.2 4 2 2 6 6 5 1 Tetratricopeptide repeat Glyco_hydro_65m PF03632.15 OEU19746.1 - 0.0096 14.8 0.0 0.061 12.2 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain TPR_15 PF13429.6 OEU19746.1 - 0.011 14.9 1.7 30 3.7 0.0 5.0 5 2 1 6 6 6 0 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.11 OEU19746.1 - 0.011 13.1 0.2 0.14 9.5 0.1 2.0 1 1 1 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit RPN7 PF10602.9 OEU19746.1 - 0.016 14.9 14.9 3.4 7.3 0.2 6.8 2 2 3 6 6 6 0 26S proteasome subunit RPN7 DUF1402 PF07182.11 OEU19746.1 - 0.02 14.0 0.7 1.1 8.3 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1402) TPR_9 PF13371.6 OEU19746.1 - 0.051 13.7 0.2 0.87 9.8 0.0 3.3 4 1 1 5 5 2 0 Tetratricopeptide repeat RF-1 PF00472.20 OEU19746.1 - 0.071 13.0 0.5 6.8 6.7 0.2 2.4 2 0 0 2 2 2 0 RF-1 domain CDC37_M PF08565.11 OEU19746.1 - 0.086 12.8 0.2 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain ANAPC5 PF12862.7 OEU19746.1 - 0.41 10.7 10.2 19 5.4 0.0 5.1 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 5 Cyclin_N PF00134.23 OEU19747.1 - 4e-12 46.0 0.4 7.9e-12 45.0 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU19747.1 - 1e-06 28.8 1.9 3.5e-05 23.8 0.1 2.8 2 1 1 3 3 3 1 Cyclin, C-terminal domain TRAPP PF04051.16 OEU19748.1 - 2.1e-38 131.3 0.0 2.4e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component UBA PF00627.31 OEU19750.1 - 4.4e-07 29.7 0.1 9.1e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 OEU19750.1 - 0.0013 18.4 0.7 0.094 12.4 0.0 2.7 2 0 0 2 2 2 2 CUE domain HNH PF01844.23 OEU19751.1 - 0.014 15.5 5.9 0.34 11.1 0.0 2.6 2 0 0 2 2 2 0 HNH endonuclease 3HCDH_N PF02737.18 OEU19751.1 - 0.03 14.2 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 OEU19752.1 - 1.9e-05 24.7 0.1 1.9e-05 24.7 0.1 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain VDE PF07137.11 OEU19753.1 - 1.3e-06 28.1 13.9 1.8e-06 27.7 13.9 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Acetyltransf_1 PF00583.25 OEU19756.1 - 7.7e-10 39.0 0.0 8.7e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU19756.1 - 5.5e-08 33.1 0.8 9.3e-08 32.4 0.8 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU19756.1 - 1.1e-05 25.4 1.5 0.0012 18.8 1.0 2.8 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OEU19756.1 - 2e-05 25.3 0.0 2.8e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU19756.1 - 3.7e-05 23.6 0.0 0.0073 16.2 0.1 2.8 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 OEU19756.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Transketolase_C PF02780.20 OEU19756.1 - 0.083 12.8 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Transketolase, C-terminal domain DUF5110 PF17137.4 OEU19756.1 - 0.083 13.2 0.4 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) DUF5086 PF16985.5 OEU19756.1 - 0.092 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) LRR_8 PF13855.6 OEU19757.1 - 1.7e-22 78.9 11.2 3.8e-07 29.8 0.1 5.1 3 2 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OEU19757.1 - 5.3e-16 58.5 13.5 3.6e-05 24.0 0.0 6.8 2 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU19757.1 - 9e-08 31.7 6.9 2.3 9.1 0.0 9.8 10 2 0 10 10 10 1 Leucine Rich Repeat LRR_9 PF14580.6 OEU19757.1 - 0.0051 16.3 0.4 3.6 7.1 0.1 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OEU19758.1 - 1.4e-21 76.0 21.2 4e-07 29.7 3.9 5.6 4 1 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OEU19758.1 - 6.1e-12 45.6 24.8 0.00087 19.6 2.7 7.4 3 1 7 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU19758.1 - 0.0026 18.1 25.7 0.56 11.0 0.2 10.7 11 2 0 11 11 11 1 Leucine Rich Repeat PA28_alpha PF02251.18 OEU19758.1 - 0.16 12.0 0.1 25 5.0 0.0 3.5 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit LRR_8 PF13855.6 OEU19759.1 - 9.8e-15 54.1 18.0 8.3e-05 22.3 0.3 5.9 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OEU19759.1 - 4.3e-07 30.2 21.6 0.23 11.9 0.1 7.3 4 3 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU19759.1 - 2.9e-05 24.0 14.6 16 6.6 0.1 8.9 8 2 0 8 8 8 2 Leucine Rich Repeat HVSL PF09749.9 OEU19760.1 - 8.2e-14 51.6 0.1 1e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3439 PF11921.8 OEU19760.1 - 8.3 6.4 7.5 6.2 6.8 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) DHHC PF01529.20 OEU19762.1 - 1.4e-30 106.1 16.1 1.4e-30 106.1 16.1 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 OEU19762.1 - 0.44 11.2 5.9 1.1 9.9 5.9 1.7 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Xpo1 PF08389.12 OEU19763.1 - 3e-11 43.6 0.5 3e-11 43.6 0.5 4.4 4 2 0 4 4 4 1 Exportin 1-like protein DUF436 PF04260.12 OEU19763.1 - 0.045 13.4 0.4 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF436) TIP120 PF08623.10 OEU19763.1 - 0.47 10.2 4.6 6.6 6.5 0.1 3.5 4 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) Glycos_transf_1 PF00534.20 OEU19764.1 - 9.6e-30 103.4 0.0 2.5e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OEU19764.1 - 7.4e-13 48.8 0.0 1.3e-12 48.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OEU19764.1 - 9.2e-10 39.1 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OEU19764.1 - 7e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OEU19764.1 - 0.0029 18.0 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Carboxyl_trans PF01039.22 OEU19765.1 - 1e-161 539.0 0.0 1.5e-161 538.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OEU19765.1 - 6.3e-50 169.6 0.2 2.6e-49 167.6 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 OEU19765.1 - 8e-47 159.9 0.0 1.4e-30 106.2 0.0 2.9 2 1 1 3 3 3 2 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 OEU19765.1 - 1.8e-32 112.2 0.0 3.8e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OEU19765.1 - 4.6e-24 84.6 0.0 1.9e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OEU19765.1 - 2.5e-11 43.2 2.2 5.7e-11 42.1 0.0 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 OEU19765.1 - 5.5e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 OEU19765.1 - 2.1e-05 24.2 0.1 5.5e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OEU19765.1 - 0.00052 19.6 0.1 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus LAL_C2 PF18603.1 OEU19765.1 - 0.1 12.8 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Prominin PF05478.11 OEU19766.1 - 0.12 10.3 0.0 0.16 9.9 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF1295 PF06966.12 OEU19767.1 - 4.6e-27 95.1 3.7 8e-27 94.3 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OEU19767.1 - 0.051 14.0 0.1 0.17 12.3 0.1 1.9 1 0 0 1 1 1 0 Phospholipid methyltransferase DUF2427 PF10348.9 OEU19767.1 - 1.9 8.3 7.9 0.28 11.0 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MAGE_N PF12440.8 OEU19767.1 - 5.8 7.7 13.7 23 5.7 5.5 3.1 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal Pkinase PF00069.25 OEU19769.1 - 5.1e-61 206.3 0.0 6.5e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU19769.1 - 8.7e-28 97.3 0.0 1.1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU19769.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU19769.1 - 0.00036 19.9 0.0 0.0042 16.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Pribosyltran PF00156.27 OEU19770.1 - 5.7e-19 68.2 0.1 7.7e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OEU19770.1 - 0.0042 16.6 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_26 PF02156.15 OEU19771.1 - 0.005 16.3 0.2 0.009 15.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Chorion_2 PF03964.15 OEU19771.1 - 0.0054 17.5 3.4 0.0054 17.5 3.4 1.9 2 0 0 2 2 2 1 Chorion family 2 SR-25 PF10500.9 OEU19771.1 - 0.49 10.0 26.2 0.026 14.1 16.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 OEU19771.1 - 0.75 10.1 17.0 1 9.7 12.4 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain SUZ PF12752.7 OEU19771.1 - 1.1 10.1 3.6 1.4 9.7 0.9 2.3 2 0 0 2 2 2 0 SUZ domain AF-4 PF05110.13 OEU19771.1 - 2.6 6.0 17.3 0.032 12.3 8.9 1.7 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF1336 PF07059.12 OEU19772.1 - 1.7e-47 162.4 0.0 2.7e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) HTH_Tnp_Tc3_1 PF11427.8 OEU19772.1 - 0.033 14.1 0.1 0.09 12.6 0.1 1.7 1 0 0 1 1 1 0 Tc3 transposase UreF PF01730.16 OEU19774.1 - 4.3e-10 40.3 0.0 6.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 UreF CRAL_TRIO_N PF03765.15 OEU19775.1 - 0.0013 18.9 0.1 0.0029 17.7 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain His_Phos_1 PF00300.22 OEU19776.1 - 7.1e-14 51.9 0.2 1.2e-12 48.0 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CbiK PF06180.11 OEU19776.1 - 0.015 14.7 0.3 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) His_Phos_2 PF00328.22 OEU19776.1 - 0.075 12.4 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Nnf1 PF03980.14 OEU19777.1 - 0.093 13.1 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Nnf1 DnaJ PF00226.31 OEU19779.1 - 1.5e-23 82.7 1.6 1.5e-23 82.7 1.6 1.7 2 0 0 2 2 2 1 DnaJ domain TraV PF09676.10 OEU19779.1 - 2.3 9.2 7.6 0.32 12.0 1.2 2.5 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Esterase_phd PF10503.9 OEU19780.1 - 1.3e-06 28.1 0.2 2.8e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 OEU19780.1 - 2.1e-05 24.5 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OEU19780.1 - 0.00037 20.2 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OEU19780.1 - 0.00052 19.5 0.0 0.001 18.6 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 OEU19780.1 - 0.028 13.3 0.4 0.11 11.4 0.4 1.8 1 1 0 1 1 1 0 Carboxylesterase family Chlorophyllase PF07224.11 OEU19780.1 - 0.076 12.0 0.2 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase AAA_25 PF13481.6 OEU19781.1 - 2.5e-23 82.7 0.0 4.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 OEU19781.1 - 9.3e-12 44.8 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 OEU19781.1 - 1.4e-10 41.5 0.0 4.5e-10 39.8 0.0 2.0 2 0 0 2 2 1 1 Toprim-like ATPase PF06745.13 OEU19781.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KaiC Toprim_4 PF13662.6 OEU19781.1 - 2.4e-06 27.9 0.0 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Toprim domain AAA_22 PF13401.6 OEU19781.1 - 1.4e-05 25.4 0.2 7.2e-05 23.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain Toprim_3 PF13362.6 OEU19781.1 - 8.1e-05 22.9 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ABC_tran PF00005.27 OEU19781.1 - 0.00033 21.2 0.0 0.00088 19.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 OEU19781.1 - 0.0014 17.7 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 OEU19781.1 - 0.0044 16.7 0.5 0.02 14.7 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU19781.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OEU19781.1 - 0.0073 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim PF01751.22 OEU19781.1 - 0.012 15.8 0.0 0.049 13.9 0.0 2.0 1 1 0 1 1 1 0 Toprim domain cobW PF02492.19 OEU19781.1 - 0.016 14.8 0.4 0.078 12.6 0.0 2.3 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OEU19781.1 - 0.025 15.1 0.4 0.025 15.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU19781.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 OEU19781.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OEU19781.1 - 0.036 14.0 0.1 0.09 12.7 0.1 1.7 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 OEU19781.1 - 0.057 13.3 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 OEU19781.1 - 0.081 12.5 0.7 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 OEU19781.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 OEU19781.1 - 0.13 12.3 0.0 0.56 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OEU19781.1 - 0.13 12.1 1.3 1.8 8.4 1.3 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Secretin_N_2 PF07655.13 OEU19781.1 - 2.6 8.6 15.9 2.4 8.8 6.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain polyprenyl_synt PF00348.17 OEU19782.1 - 5.3e-68 228.8 0.2 6.9e-68 228.5 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OEU19782.1 - 0.0014 18.3 0.8 0.0023 17.6 0.8 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 zf-ribbon_3 PF13248.6 OEU19785.1 - 0.0024 17.2 2.2 0.41 10.1 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain ECF_trnsprt PF12822.7 OEU19785.1 - 0.0048 17.0 1.5 0.0088 16.2 1.5 1.4 1 0 0 1 1 1 1 ECF transporter, substrate-specific component Lar_restr_allev PF14354.6 OEU19785.1 - 0.02 15.2 0.2 0.033 14.6 0.2 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.7 OEU19785.1 - 0.069 13.2 1.4 0.19 11.8 1.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon TraU PF06834.11 OEU19785.1 - 0.088 12.1 1.0 0.12 11.6 1.0 1.1 1 0 0 1 1 1 0 TraU protein PriA_CRR PF18319.1 OEU19785.1 - 0.18 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain zinc_ribbon_2 PF13240.6 OEU19785.1 - 0.2 11.4 2.3 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 OEU19785.1 - 0.41 10.2 2.9 7.2 6.2 2.9 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding DUF3663 PF12404.8 OEU19788.1 - 0.1 12.6 0.3 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Peptidase MG4 PF17789.1 OEU19791.1 - 0.037 14.2 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Macroglobulin domain MG4 DHHC PF01529.20 OEU19792.1 - 1e-30 106.5 21.8 1e-30 106.5 21.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 OEU19792.1 - 0.54 11.0 6.0 1.4 9.6 6.0 1.7 1 0 0 1 1 1 0 Insulin-like growth factor binding protein 2OG-FeII_Oxy_3 PF13640.6 OEU19793.1 - 2e-07 31.8 0.0 3.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.31 OEU19794.1 - 7.1e-11 42.1 0.0 7.1e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain SUIM_assoc PF16619.5 OEU19794.1 - 0.03 14.4 0.9 0.14 12.3 0.9 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 OEU19796.1 - 1.7e-06 28.5 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU19796.1 - 2.2e-06 27.6 0.0 0.02 15.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OEU19796.1 - 0.00072 19.9 0.4 0.014 15.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OEU19796.1 - 0.0023 18.5 0.0 0.0073 16.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU19796.1 - 0.0058 16.9 0.0 4.7 7.7 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2203 PF09969.9 OEU19796.1 - 0.39 11.4 0.1 0.39 11.4 0.1 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DHR10 PF18595.1 OEU19796.1 - 2.4 8.3 11.3 3.4 7.7 8.5 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DisA_N PF02457.16 OEU19797.1 - 0.077 12.6 0.3 0.077 12.6 0.3 1.5 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding BAF1_ABF1 PF04684.13 OEU19797.1 - 0.25 10.3 26.9 0.081 12.0 24.5 1.4 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EamA PF00892.20 OEU19798.1 - 2.2e-08 34.3 28.4 0.0001 22.5 9.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family RecG_N PF17190.4 OEU19798.1 - 0.077 13.7 0.1 0.23 12.2 0.1 1.7 2 0 0 2 2 2 0 RecG N-terminal helical domain Peptidase_M24 PF00557.24 OEU19799.1 - 1.8e-45 155.2 0.1 2.4e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OEU19799.1 - 3.2e-16 59.3 7.6 7.5e-16 58.2 7.6 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OEU19799.1 - 0.017 15.2 4.9 0.017 15.2 4.9 2.4 2 0 0 2 2 2 0 MYND finger DUF2116 PF09889.9 OEU19799.1 - 0.18 11.8 1.1 0.42 10.6 1.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Sel1 PF08238.12 OEU19800.1 - 1.9e-16 60.1 22.9 0.0024 18.5 0.1 10.9 11 0 0 11 11 11 5 Sel1 repeat GTP_EFTU PF00009.27 OEU19801.1 - 7.9e-52 175.6 0.1 1.2e-51 175.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OEU19801.1 - 7.2e-45 151.5 0.6 1.5e-44 150.5 0.6 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OEU19801.1 - 1.4e-19 69.9 0.0 2.9e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OEU19801.1 - 8.8e-11 42.1 1.8 2.1e-10 40.8 1.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU19801.1 - 3.9e-05 23.7 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OEU19801.1 - 0.00056 19.5 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 OEU19801.1 - 0.023 14.8 0.0 0.071 13.2 0.0 1.9 1 1 0 1 1 1 0 Elongation Factor G, domain II RF3_C PF16658.5 OEU19801.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain DUF2722 PF10846.8 OEU19801.1 - 0.091 11.7 0.4 0.13 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pkinase PF00069.25 OEU19802.1 - 1.5e-27 96.6 0.0 1.5e-26 93.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU19802.1 - 1.5e-12 47.3 0.0 1.2e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU19802.1 - 5.2e-05 23.3 0.2 0.00011 22.2 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU19802.1 - 0.0026 17.2 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU19802.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OEU19802.1 - 0.021 13.6 0.2 0.027 13.2 0.2 1.3 1 1 0 1 1 1 0 Fungal protein kinase Rsa3 PF14615.6 OEU19802.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Ribosome-assembly protein 3 TPR_1 PF00515.28 OEU19803.1 - 2.7e-08 33.3 0.3 0.33 10.8 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OEU19803.1 - 2.4e-07 30.9 0.1 0.0023 18.2 0.1 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19803.1 - 1.8e-06 27.6 0.3 0.015 15.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19803.1 - 0.00023 21.1 0.4 0.26 11.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19803.1 - 0.00026 20.8 0.0 2 8.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU19803.1 - 0.0053 17.5 0.0 3.9 8.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU19803.1 - 0.0057 16.3 0.4 0.4 10.4 0.0 3.1 3 1 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 OEU19803.1 - 0.0072 16.8 0.0 1.8 9.1 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU19803.1 - 0.012 15.4 0.8 8.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OEU19803.1 - 0.048 14.1 0.0 2.1 8.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU19803.1 - 0.072 13.8 0.3 1.3 9.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OEU19803.1 - 0.13 12.9 0.0 0.57 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_T PF00929.24 OEU19804.1 - 5.1e-11 43.4 0.0 6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease ABM PF03992.16 OEU19805.1 - 0.00069 19.7 0.0 0.00085 19.4 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EamA PF00892.20 OEU19806.1 - 2.7e-13 50.3 31.9 2.5e-07 30.9 9.8 2.9 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OEU19806.1 - 1.4e-06 27.8 2.6 1.4e-06 27.8 2.6 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 OEU19806.1 - 0.0043 16.8 3.6 0.0043 16.8 3.6 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) TMEM234 PF10639.9 OEU19806.1 - 2.8 8.0 12.8 0.76 9.8 0.9 3.7 3 1 1 4 4 4 0 Putative transmembrane family 234 PAP_assoc PF03828.19 OEU19807.1 - 3.6e-10 39.9 0.1 9.7e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OEU19807.1 - 0.00012 22.3 0.9 0.00026 21.2 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 OEU19807.1 - 0.00049 20.1 0.0 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Uso1_p115_C PF04871.13 OEU19807.1 - 1.2 9.5 25.4 0.19 12.1 5.2 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 OEU19807.1 - 2.7 7.5 15.8 1.3 8.5 8.4 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit HAUS6_N PF14661.6 OEU19807.1 - 3.8 7.0 15.1 7.1 6.1 5.5 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 OEU19807.1 - 4.9 5.7 14.2 0.96 8.0 0.8 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-CCHC PF00098.23 OEU19808.1 - 0.0064 16.5 3.3 0.014 15.4 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle TPR_10 PF13374.6 OEU19809.1 - 0.00073 19.3 0.2 0.21 11.5 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU19809.1 - 0.00088 19.5 0.2 0.27 11.5 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19809.1 - 0.015 15.4 0.0 0.21 11.8 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19809.1 - 0.096 12.9 0.0 9.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 OEU19810.1 - 2e-39 135.0 0.0 3.2e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU19810.1 - 1.1e-05 25.9 0.0 7.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU19810.1 - 7e-05 23.1 0.1 0.071 13.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 OEU19810.1 - 0.00066 19.7 0.0 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain Virul_Fac PF10139.9 OEU19810.1 - 0.0021 16.4 0.0 0.0028 16.0 0.0 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor AAA_28 PF13521.6 OEU19810.1 - 0.0041 17.4 0.0 0.0059 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OEU19810.1 - 0.0045 17.5 0.0 0.0093 16.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 OEU19810.1 - 0.005 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OEU19810.1 - 0.0077 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 OEU19810.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OEU19810.1 - 0.013 15.5 0.0 0.051 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU19810.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 OEU19810.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OEU19810.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 OEU19810.1 - 0.032 14.8 0.0 0.057 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OEU19810.1 - 0.033 13.8 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF433 PF04255.14 OEU19810.1 - 0.058 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) AAA_33 PF13671.6 OEU19810.1 - 0.075 13.2 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OEU19810.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OEU19810.1 - 0.13 11.9 0.0 0.91 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OEU19810.1 - 0.21 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OEU19810.1 - 0.21 10.8 0.0 0.46 9.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 OEU19810.1 - 0.22 10.7 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase PEX-1N PF09262.11 OEU19811.1 - 9.8e-14 51.5 1.7 1.3e-13 51.2 0.3 2.0 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal Sec7 PF01369.20 OEU19813.1 - 1.8e-46 158.1 0.0 2.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain QWRF PF04484.12 OEU19813.1 - 0.14 11.9 3.0 0.2 11.4 3.0 1.1 1 0 0 1 1 1 0 QWRF family Snf7 PF03357.21 OEU19814.1 - 1.3e-27 96.5 23.7 1.9e-27 96.0 23.7 1.2 1 0 0 1 1 1 1 Snf7 DUF2840 PF11000.8 OEU19814.1 - 0.041 13.7 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) DUF4946 PF16304.5 OEU19814.1 - 0.13 11.9 4.2 0.23 11.2 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4946) FRG1 PF06229.12 OEU19814.1 - 0.37 10.5 7.0 0.3 10.8 4.5 2.0 1 1 0 2 2 2 0 FRG1-like domain RNA_binding PF01877.17 OEU19814.1 - 6.3 7.1 10.0 4.8 7.5 3.7 2.3 1 1 1 2 2 2 0 RNA binding WW PF00397.26 OEU19815.1 - 0.021 14.9 1.1 0.046 13.8 1.1 1.6 1 0 0 1 1 1 0 WW domain Ferric_reduct PF01794.19 OEU19816.1 - 3.1e-14 53.2 0.2 3.1e-14 53.2 0.2 2.8 2 1 1 3 3 3 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OEU19816.1 - 1.8e-10 41.2 0.2 4.9e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OEU19816.1 - 2.3e-06 27.7 0.0 6.8e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain PTS_EIIC PF02378.18 OEU19816.1 - 0.058 12.4 5.4 4.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase system, EIIC DUF4405 PF14358.6 OEU19816.1 - 5.3 7.7 7.9 25 5.5 2.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) EMC3_TMCO1 PF01956.16 OEU19817.1 - 1.4e-33 116.0 0.4 1.4e-33 116.0 0.4 1.5 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Fe_hyd_lg_C PF02906.14 OEU19818.1 - 2.2e-07 30.8 0.0 2.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_lg_C PF02906.14 OEU19819.1 - 9.5e-26 90.9 0.2 1.2e-25 90.6 0.2 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 OEU19820.1 - 3.1e-17 63.2 0.0 4.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU19820.1 - 0.016 15.7 0.1 0.037 14.5 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Cadherin_C_2 PF16492.5 OEU19821.1 - 0.14 12.9 3.2 2.5 8.9 0.1 2.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal LapA_dom PF06305.11 OEU19821.1 - 0.33 10.8 1.9 27 4.7 0.0 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 OEU19821.1 - 0.4 11.6 1.5 1.5 9.8 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 OEU19821.1 - 0.57 10.8 7.1 0.34 11.6 3.2 2.6 2 1 1 3 3 3 0 WW domain-binding protein 1 Ly49 PF08391.10 OEU19821.1 - 1.7 9.0 12.1 0.057 13.8 2.2 2.8 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Baculo_11_kDa PF06143.11 OEU19821.1 - 1.9 8.1 6.8 0.26 10.9 1.4 2.3 1 1 1 2 2 2 0 Baculovirus 11 kDa family DUF443 PF04276.12 OEU19821.1 - 3.4 7.4 7.4 0.38 10.5 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF443) SpoIIM PF01944.17 OEU19821.1 - 4.4 7.3 8.9 0.57 10.2 3.8 1.9 1 1 1 2 2 2 0 Stage II sporulation protein M Kinesin PF00225.23 OEU19822.1 - 1.4e-82 277.3 0.7 1.4e-82 277.3 0.7 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OEU19822.1 - 1.7e-14 54.0 0.1 4.9e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 OEU19822.1 - 0.00054 20.4 0.8 0.0017 18.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OEU19822.1 - 0.33 11.2 2.8 0.45 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain YqzE PF14038.6 OEU19822.1 - 1.2 9.2 4.2 4.6 7.3 4.2 2.1 1 0 0 1 1 1 0 YqzE-like protein TMEM252 PF15664.5 OEU19823.1 - 0.027 14.2 0.2 0.095 12.4 0.2 2.0 1 0 0 1 1 1 0 Transmembrane protein 252 family FAM70 PF14967.6 OEU19823.1 - 0.14 11.6 1.5 0.68 9.3 0.1 2.3 2 0 0 2 2 2 0 FAM70 protein Ureide_permease PF07168.11 OEU19823.1 - 7.8 5.1 5.3 1.1 7.9 0.3 1.9 2 0 0 2 2 2 0 Ureide permease Peptidase_C12 PF01088.21 OEU19825.1 - 9.4e-63 211.8 0.1 1.3e-62 211.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 OEU19825.1 - 1.3e-14 53.8 1.5 2.5e-14 52.9 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases PP2C PF00481.21 OEU19826.1 - 1.8e-26 93.3 0.0 2.1e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU19826.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C Na_H_Exchanger PF00999.21 OEU19828.1 - 7.8e-52 176.3 33.0 9.4e-52 176.1 33.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 OEU19828.1 - 1.9e-14 53.9 0.0 4.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain AdoHcyase_NAD PF00670.21 OEU19828.1 - 0.43 10.6 1.3 2.1 8.4 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UPF0524 PF15823.5 OEU19832.1 - 0.039 13.3 0.6 0.073 12.5 0.6 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 Ku PF02735.16 OEU19833.1 - 6.5e-32 110.9 0.0 1.4e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OEU19833.1 - 7.9e-10 38.8 3.0 4.5e-08 33.1 0.7 3.3 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 OEU19833.1 - 3.8e-05 23.3 0.3 0.00012 21.7 0.3 1.9 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 OEU19833.1 - 0.011 16.4 0.0 0.011 16.4 0.0 4.1 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm DNA_pol_phi PF04931.13 OEU19833.1 - 0.088 10.9 23.3 0.21 9.6 23.3 1.6 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 OEU19833.1 - 5.2 5.5 14.9 12 4.3 14.9 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LEDGF PF11467.8 OEU19835.1 - 0.0017 17.9 0.7 0.006 16.2 0.7 1.8 2 0 0 2 2 2 1 Lens epithelium-derived growth factor (LEDGF) Med26 PF08711.11 OEU19835.1 - 0.0071 16.3 2.3 0.017 15.1 2.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain KilA-N PF04383.13 OEU19835.1 - 0.098 12.5 0.7 0.59 10.0 0.1 2.5 3 1 0 3 3 3 0 KilA-N domain DUF2183 PF09949.9 OEU19836.1 - 0.18 12.1 0.2 0.47 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) DUF4033 PF13225.6 OEU19837.1 - 2e-27 95.0 0.1 3e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Bestrophin PF01062.21 OEU19838.1 - 1e-34 120.3 0.1 2.5e-34 119.0 0.1 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pex24p PF06398.11 OEU19838.1 - 0.027 13.5 0.0 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin SID-1_RNA_chan PF13965.6 OEU19838.1 - 0.11 10.9 0.3 0.16 10.4 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4724 PF15852.5 OEU19838.1 - 0.25 11.8 2.1 0.57 10.7 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) LZ_Tnp_IS66 PF13007.7 OEU19838.1 - 1.1 10.1 4.9 30 5.5 0.1 2.7 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain VRR_NUC PF08774.11 OEU19839.1 - 1.2e-09 38.2 0.6 0.00097 19.2 0.0 3.5 3 1 1 4 4 4 2 VRR-NUC domain Presenilin PF01080.17 OEU19839.1 - 0.57 8.9 4.7 0.97 8.1 4.7 1.3 1 0 0 1 1 1 0 Presenilin PhyH PF05721.13 OEU19840.1 - 3.9e-15 56.7 0.0 7.5e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UQ_con PF00179.26 OEU19841.1 - 9.8e-14 51.2 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OEU19841.1 - 0.0059 16.9 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 OEU19841.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain DUF2040 PF09745.9 OEU19842.1 - 1.1e-28 99.7 27.3 1.1e-28 99.7 27.3 2.9 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) STI1 PF17830.1 OEU19843.1 - 0.0015 18.4 0.2 0.0028 17.5 0.1 1.5 2 0 0 2 2 2 1 STI1 domain HEAT_2 PF13646.6 OEU19844.1 - 0.00051 20.4 2.4 0.8 10.1 0.3 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 OEU19844.1 - 0.0037 17.4 0.5 9.8 6.7 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat DUF3535 PF12054.8 OEU19844.1 - 0.094 11.9 0.1 0.34 10.1 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3535) CLASP_N PF12348.8 OEU19844.1 - 0.13 11.8 0.0 26 4.3 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 OEU19844.1 - 0.76 10.3 15.5 9.1 6.9 0.4 6.2 6 0 0 6 6 6 0 HEAT-like repeat DUF819 PF05684.12 OEU19845.1 - 3.7e-17 62.4 22.4 1.7e-16 60.3 17.5 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF819) Glt_symporter PF03616.14 OEU19845.1 - 0.0044 15.7 4.8 0.0082 14.9 4.8 1.5 1 1 0 1 1 1 1 Sodium/glutamate symporter DUF3139 PF11337.8 OEU19846.1 - 0.14 12.8 0.0 0.51 11.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SAPS PF04499.15 OEU19846.1 - 0.61 8.8 6.0 1.1 7.9 6.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Methyltransf_22 PF13383.6 OEU19847.1 - 4.5e-23 82.1 0.6 5e-23 82.0 0.6 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OEU19847.1 - 0.0047 17.0 0.2 0.0062 16.6 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Peptidase_M43 PF05572.13 OEU19847.1 - 0.097 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Clat_adaptor_s PF01217.20 OEU19848.1 - 0.015 15.3 0.9 0.058 13.3 0.9 2.0 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Clat_adaptor_s PF01217.20 OEU19849.1 - 1.5e-49 167.6 4.2 3.8e-49 166.3 4.2 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain HA PF03457.14 OEU19850.1 - 4e-33 113.5 7.1 1.7e-16 60.3 1.4 2.3 2 0 0 2 2 2 2 Helicase associated domain Cation_ATPase_C PF00689.21 OEU19851.1 - 0.051 13.3 0.4 0.067 12.9 0.4 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus ABC2_membrane PF01061.24 OEU19852.1 - 3.6e-37 127.8 24.3 3.6e-37 127.8 24.3 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OEU19852.1 - 7e-20 72.0 0.0 1.3e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OEU19852.1 - 6.8e-05 22.5 0.6 0.00016 21.3 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU19852.1 - 0.0005 20.0 0.2 0.001 19.0 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 OEU19852.1 - 0.014 15.0 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 OEU19852.1 - 0.015 14.5 25.9 0.022 13.9 24.1 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein PDR_assoc PF08370.11 OEU19852.1 - 0.019 14.7 0.8 9.2 6.1 0.1 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_21 PF13304.6 OEU19852.1 - 0.025 14.4 0.4 0.36 10.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OEU19852.1 - 0.083 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OEU19852.1 - 0.1 13.1 0.2 0.19 12.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain IMP2_N PF18590.1 OEU19853.1 - 5.6e-24 84.5 0.0 7.6e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain OST3_OST6 PF04756.13 OEU19854.1 - 1.4e-05 24.6 0.0 1.4e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 OEU19854.1 - 2.7e-05 24.1 0.0 3.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Citrate_synt PF00285.21 OEU19855.1 - 1.6e-102 343.3 0.0 1.9e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 OEU19855.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold GST_N_2 PF13409.6 OEU19856.1 - 3.8e-13 49.5 0.0 8.8e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU19856.1 - 6.1e-09 35.8 0.1 3.5e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU19856.1 - 1.8e-07 31.3 0.3 9.7e-07 28.9 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OEU19856.1 - 0.00033 21.0 0.0 1.2 9.5 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU19856.1 - 0.00035 20.7 0.0 0.0007 19.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU19856.1 - 0.063 13.6 0.0 6.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain Lac_bphage_repr PF06543.12 OEU19857.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Menin PF05053.13 OEU19857.1 - 0.23 9.8 6.6 0.25 9.7 6.6 1.0 1 0 0 1 1 1 0 Menin Pannexin_like PF12534.8 OEU19857.1 - 1.3 8.0 4.2 2 7.4 4.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF334 PF03904.13 OEU19857.1 - 4.2 6.9 5.3 5.8 6.4 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Presenilin PF01080.17 OEU19857.1 - 7.2 5.3 6.5 8.9 5.0 6.5 1.1 1 0 0 1 1 1 0 Presenilin Ras PF00071.22 OEU19858.1 - 6.4e-65 217.7 0.3 7.2e-65 217.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU19858.1 - 4.7e-36 123.6 0.9 6.6e-36 123.2 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU19858.1 - 8e-18 64.5 0.1 9.6e-18 64.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OEU19858.1 - 1.6e-07 30.9 0.2 1.9e-07 30.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OEU19858.1 - 2.8e-07 30.3 0.3 7.1e-07 29.0 0.2 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU19858.1 - 0.00041 20.3 0.4 0.89 9.4 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OEU19858.1 - 0.00045 19.7 0.1 0.00058 19.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OEU19858.1 - 0.00053 19.2 4.7 0.0015 17.8 1.3 2.5 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OEU19858.1 - 0.00064 19.8 0.1 0.00092 19.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OEU19858.1 - 0.0062 16.3 0.2 0.015 15.1 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OEU19858.1 - 0.018 14.6 0.1 0.076 12.5 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 OEU19858.1 - 0.031 14.7 0.0 0.15 12.5 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1_Xtn PF16897.5 OEU19858.1 - 0.055 13.5 0.2 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_7 PF12775.7 OEU19858.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OEU19858.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain CTU2 PF10288.9 OEU19859.1 - 0.01 16.1 2.9 0.016 15.4 2.9 1.5 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 FYDLN_acid PF09538.10 OEU19859.1 - 0.029 15.0 6.5 0.064 13.9 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TRAP_alpha PF03896.16 OEU19859.1 - 0.087 12.0 4.1 0.13 11.4 4.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit IFT57 PF10498.9 OEU19859.1 - 0.19 10.7 6.7 0.24 10.3 6.2 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Cwf_Cwc_15 PF04889.12 OEU19859.1 - 0.42 10.3 11.9 0.76 9.5 11.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OEU19859.1 - 1.3 8.3 11.6 2 7.7 11.6 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OEU19859.1 - 6.9 4.6 12.2 9 4.3 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi TPR_12 PF13424.6 OEU19860.1 - 2.1e-18 66.4 8.1 2.6e-11 43.6 0.6 4.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19860.1 - 2.4e-09 36.6 9.0 0.011 15.8 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19860.1 - 7.5e-08 31.9 15.7 0.016 15.0 0.0 6.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU19860.1 - 8.9e-08 31.6 10.1 0.01 15.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU19860.1 - 8.6e-07 28.6 10.6 0.00018 21.3 0.2 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19860.1 - 5.3e-05 23.1 8.0 0.0076 16.4 0.0 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU19860.1 - 7.6e-05 22.3 6.7 0.11 12.2 0.0 3.9 5 0 0 5 5 5 2 TPR repeat Pyr_excise PF03013.14 OEU19860.1 - 0.018 15.0 2.2 0.056 13.4 0.1 2.4 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase THP2 PF09432.10 OEU19860.1 - 0.019 15.0 2.8 0.019 15.0 2.8 2.9 2 1 1 3 3 3 0 Tho complex subunit THP2 TPR_6 PF13174.6 OEU19860.1 - 0.024 15.3 2.3 84 4.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU19860.1 - 0.039 14.8 1.5 14 6.8 0.0 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU19860.1 - 0.045 14.4 0.7 5.5 7.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OEU19860.1 - 0.11 13.0 3.5 1.2 9.7 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1947 PF09183.10 OEU19860.1 - 0.13 12.6 0.2 0.46 10.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Tom37_C PF11801.8 OEU19860.1 - 0.14 12.2 3.3 0.16 11.9 0.3 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain KaiA PF07688.12 OEU19860.1 - 0.27 11.4 5.4 0.41 10.8 1.1 2.6 2 1 0 2 2 2 0 KaiA C-terminal domain ANAPC5 PF12862.7 OEU19860.1 - 0.27 11.3 6.6 9.2 6.4 3.3 3.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 HlyIII PF03006.20 OEU19861.1 - 2.5e-17 63.4 8.6 3e-17 63.1 8.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.6 OEU19861.1 - 0.00036 20.4 0.2 0.023 14.7 0.0 2.9 3 0 0 3 3 3 1 Leucine Rich repeat CENP-B_dimeris PF09026.10 OEU19864.1 - 0.031 14.7 8.1 0.051 14.0 8.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 OEU19864.1 - 0.033 14.1 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CRS1_YhbY PF01985.21 OEU19864.1 - 0.039 14.1 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain RXT2_N PF08595.11 OEU19864.1 - 0.08 13.0 2.3 0.13 12.3 2.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Mpp10 PF04006.12 OEU19864.1 - 0.084 11.3 3.1 0.1 11.0 3.1 1.1 1 0 0 1 1 1 0 Mpp10 protein PBP1_TM PF14812.6 OEU19864.1 - 0.51 10.7 10.1 0.97 9.8 10.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BDHCT_assoc PF16204.5 OEU19864.1 - 6.1 6.5 5.7 11 5.7 5.7 1.4 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein NOA36 PF06524.12 OEU19864.1 - 6.8 5.9 11.4 9.5 5.4 11.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 OEU19864.1 - 8.8 5.3 14.7 12 4.9 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Abhydrolase_6 PF12697.7 OEU19865.1 - 1.2e-12 48.9 0.0 1.7e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU19865.1 - 6.8e-09 35.3 0.0 8.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU19865.1 - 1e-08 35.2 0.1 1.5e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 OEU19865.1 - 0.00033 20.8 0.0 0.00067 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 OEU19865.1 - 0.00045 19.3 0.0 0.0007 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 OEU19865.1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase PF00151.19 OEU19865.1 - 0.0056 16.0 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 OEU19865.1 - 0.0085 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 OEU19865.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 OEU19865.1 - 0.075 12.7 0.0 4.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Trp_Tyr_perm PF03222.13 OEU19866.1 - 3.2e-32 112.1 15.7 5.2e-31 108.1 15.7 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 OEU19866.1 - 7.2e-06 25.0 13.4 6.3e-05 21.9 13.4 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GlutR_dimer PF00745.20 OEU19867.1 - 0.11 13.0 3.5 0.36 11.3 0.3 2.9 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain YlbD_coat PF14071.6 OEU19867.1 - 2.1 8.6 25.5 0.048 13.9 4.4 3.5 3 1 0 3 3 3 0 Putative coat protein Proteasome PF00227.26 OEU19868.1 - 2.8e-53 180.2 0.0 3.4e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU19868.1 - 5.6e-13 48.3 0.0 1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RSF PF14876.6 OEU19869.1 - 0.0025 16.8 0.5 0.0041 16.1 0.5 1.2 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator RRM_1 PF00076.22 OEU19869.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THOC7 PF05615.13 OEU19870.1 - 2.4e-05 24.6 1.6 3.2e-05 24.2 1.4 1.3 1 1 0 1 1 1 1 Tho complex subunit 7 Spt20 PF12090.8 OEU19871.1 - 0.024 14.3 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 OEU19872.1 - 0.012 15.7 0.7 0.012 15.7 0.7 3.7 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SOUL PF04832.12 OEU19873.1 - 1.4e-35 122.9 0.6 1.6e-24 86.9 0.0 2.0 1 1 1 2 2 2 2 SOUL heme-binding protein adh_short PF00106.25 OEU19874.1 - 1e-11 44.7 0.4 0.00023 20.7 0.2 3.1 2 1 1 3 3 3 3 short chain dehydrogenase Epimerase PF01370.21 OEU19874.1 - 3.7e-08 33.1 0.0 5.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 OEU19874.1 - 1.1e-06 28.4 0.1 0.092 12.3 0.3 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 OEU19874.1 - 0.00034 19.8 0.1 0.0005 19.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OEU19874.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Peptidase_S9 PF00326.21 OEU19875.1 - 2.3e-43 148.2 0.0 4e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OEU19875.1 - 1.2e-10 41.3 1.1 4.9e-10 39.3 1.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OEU19875.1 - 5.8e-08 32.6 0.7 7.2e-05 22.5 1.1 2.2 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 OEU19875.1 - 5.8e-05 22.5 0.0 0.025 13.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU19875.1 - 7.1e-05 22.6 3.1 0.16 11.6 2.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OEU19875.1 - 0.00071 19.5 0.1 0.34 10.7 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU19875.1 - 0.00096 19.8 3.0 0.0045 17.6 3.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 OEU19875.1 - 0.0015 17.3 0.1 0.066 11.9 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 OEU19875.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DPPIV_N PF00930.21 OEU19875.1 - 0.12 11.1 0.3 37 2.9 0.1 3.3 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region ACBP PF00887.19 OEU19876.1 - 6e-17 61.6 0.1 9.9e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 OEU19876.1 - 1.7e-13 50.7 0.4 1.6e-06 28.6 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU19876.1 - 7.7e-13 48.3 4.3 3e-07 30.6 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OEU19876.1 - 2.2e-12 47.4 0.1 1.4e-07 32.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU19876.1 - 6e-09 36.0 0.2 2.2e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU19876.1 - 4.2e-07 29.8 0.1 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat 2_5_RNA_ligase2 PF13563.6 OEU19878.1 - 0.00024 21.0 0.1 0.0063 16.4 0.1 2.8 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily RPN2_C PF18004.1 OEU19878.1 - 0.097 12.6 3.0 0.22 11.4 3.0 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF21 PF01595.20 OEU19879.1 - 2.1e-30 105.7 0.1 3e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain PHO4 PF01384.20 OEU19879.1 - 0.055 12.5 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF2633 PF11119.8 OEU19879.1 - 0.98 9.4 2.7 1.1 9.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) zf-RanBP PF00641.18 OEU19880.1 - 2.2e-05 23.7 3.6 6.7e-05 22.1 3.6 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Got1 PF04178.12 OEU19881.1 - 4.5e-24 85.0 9.8 6.8e-24 84.5 9.8 1.3 1 1 0 1 1 1 1 Got1/Sft2-like family DUF3546 PF12066.8 OEU19882.1 - 2.5e-11 43.7 4.3 7e-11 42.3 4.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OEU19882.1 - 0.0063 16.9 1.2 0.022 15.1 0.1 2.5 2 0 0 2 2 2 1 Arsenite-resistance protein 2 LysM PF01476.20 OEU19883.1 - 0.0025 17.8 0.0 0.0068 16.4 0.0 1.8 2 0 0 2 2 2 1 LysM domain UBA_4 PF14555.6 OEU19883.1 - 0.063 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Sulfotransfer_1 PF00685.27 OEU19885.1 - 2.8e-60 204.1 1.3 3.4e-60 203.8 1.3 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU19885.1 - 1.2e-05 25.8 0.0 5.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family SpoVIF PF14069.6 OEU19885.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F DUF1642 PF07852.11 OEU19885.1 - 0.057 14.0 0.3 1.8 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) 2OG-FeII_Oxy_3 PF13640.6 OEU19886.1 - 4.2e-16 59.6 0.2 1.6e-15 57.7 0.1 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 OEU19886.1 - 0.00045 20.7 6.7 0.00045 20.7 6.7 2.6 2 0 0 2 2 2 2 ShK domain-like Xan_ur_permease PF00860.20 OEU19888.1 - 1e-11 44.2 1.0 1.2e-11 43.9 1.0 1.0 1 0 0 1 1 1 1 Permease family CENP-S PF15630.6 OEU19889.1 - 2.8e-13 50.1 0.1 6.5e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OEU19889.1 - 2.3e-05 24.4 0.0 8.8e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 OEU19889.1 - 0.072 13.1 0.1 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated Mpv17_PMP22 PF04117.12 OEU19890.1 - 4.5e-17 62.0 0.4 4.5e-17 62.0 0.4 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family GW PF13457.6 OEU19891.1 - 0.11 13.1 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain PT PF04886.12 OEU19892.1 - 3 7.5 21.0 1.3e+02 2.2 21.0 2.4 1 1 0 1 1 1 0 PT repeat RVT_1 PF00078.27 OEU19894.1 - 2e-07 30.7 0.0 6.1e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU19894.1 - 0.016 15.9 0.9 0.068 13.9 0.9 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase LBR_tudor PF09465.10 OEU19894.1 - 0.12 12.1 0.2 0.33 10.8 0.2 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF2935 PF11155.8 OEU19895.1 - 0.016 15.6 0.1 0.037 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) IFT20 PF14931.6 OEU19895.1 - 0.084 13.0 3.3 0.17 12.0 3.3 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 zf-RING_2 PF13639.6 OEU19897.1 - 6.2e-12 45.6 11.1 7e-12 45.5 11.1 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU19897.1 - 1.5e-07 31.0 6.3 1.5e-07 31.0 6.3 1.5 2 0 0 2 2 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OEU19897.1 - 3.3e-06 27.1 6.2 4.5e-06 26.6 6.2 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OEU19897.1 - 3.5e-06 26.8 7.7 5.3e-06 26.2 7.7 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU19897.1 - 3.5e-06 27.0 6.3 3.3e-05 23.8 7.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OEU19897.1 - 5.6e-06 26.5 12.9 1.6e-05 25.1 12.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU19897.1 - 6.4e-06 25.9 10.1 1e-05 25.2 10.1 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OEU19897.1 - 0.0001 21.8 8.7 0.00014 21.4 8.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OEU19897.1 - 0.00019 21.5 10.6 0.00051 20.2 10.6 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 OEU19897.1 - 0.007 16.2 1.7 0.0093 15.8 1.7 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OEU19897.1 - 0.0072 16.4 7.7 0.016 15.3 7.7 1.6 1 1 0 1 1 1 1 RING-variant domain zf-RING_5 PF14634.6 OEU19897.1 - 0.017 15.1 11.5 0.041 13.8 11.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 OEU19897.1 - 0.036 14.4 7.7 0.067 13.5 7.7 1.5 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OEU19897.1 - 0.12 12.5 11.7 0.54 10.5 11.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OEU19897.1 - 0.55 10.2 9.3 0.69 9.9 3.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_5 PF17121.5 OEU19897.1 - 0.76 9.7 9.2 2.4 8.1 9.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA PF00004.29 OEU19899.1 - 5.4e-34 117.5 0.0 7.6e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OEU19899.1 - 3e-06 27.6 0.2 1.3e-05 25.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU19899.1 - 1.1e-05 25.9 1.1 1.5e-05 25.5 0.2 1.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 OEU19899.1 - 1.9e-05 24.7 0.1 7.3e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OEU19899.1 - 0.00011 22.0 0.1 0.00033 20.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OEU19899.1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OEU19899.1 - 0.00073 19.0 0.1 0.0029 17.0 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OEU19899.1 - 0.00074 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OEU19899.1 - 0.0016 18.2 0.2 0.0052 16.5 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU19899.1 - 0.0019 18.8 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OEU19899.1 - 0.0028 17.3 0.8 0.23 11.0 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OEU19899.1 - 0.0038 17.4 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OEU19899.1 - 0.0052 16.5 0.2 0.024 14.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU19899.1 - 0.0058 16.6 0.0 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OEU19899.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OEU19899.1 - 0.018 14.8 0.1 0.044 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OEU19899.1 - 0.031 14.0 0.0 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 OEU19899.1 - 0.035 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 OEU19899.1 - 0.059 12.7 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 1 0 KaiC TsaE PF02367.17 OEU19899.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OEU19899.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 OEU19899.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OEU19899.1 - 0.15 11.1 0.0 14 4.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PIF1 PF05970.14 OEU19899.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ATPase_2 PF01637.18 OEU19899.1 - 0.21 11.5 0.0 0.66 9.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OEU19899.1 - 0.24 10.9 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region 4F5 PF04419.14 OEU19901.1 - 4.2e-06 27.5 11.0 4.2e-06 27.5 11.0 3.8 1 1 1 2 2 2 1 4F5 protein family CAF-1_p60_C PF15512.6 OEU19901.1 - 0.032 14.7 2.9 0.043 14.3 2.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal ATP-grasp_2 PF08442.10 OEU19901.1 - 0.34 10.5 7.2 0.41 10.2 7.2 1.1 1 0 0 1 1 1 0 ATP-grasp domain TAF4 PF05236.14 OEU19901.1 - 0.47 10.2 16.7 0.51 10.0 16.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Exo_endo_phos PF03372.23 OEU19902.1 - 4.9e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cupin_8 PF13621.6 OEU19903.1 - 2.5e-16 60.2 10.0 1.5e-15 57.6 10.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU19903.1 - 0.00039 20.0 0.0 0.00083 18.9 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OEU19903.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase PHD PF00628.29 OEU19904.1 - 2.1e-08 33.9 4.2 3.3e-08 33.3 4.2 1.3 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OEU19904.1 - 5e-05 22.8 2.0 5e-05 22.8 2.0 1.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 OEU19904.1 - 0.051 13.8 4.6 0.097 12.9 4.6 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_9 PF13901.6 OEU19904.1 - 0.12 12.4 2.0 0.13 12.2 2.0 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RanBP PF00641.18 OEU19904.1 - 0.19 11.1 0.5 0.19 11.1 0.5 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-RING_2 PF13639.6 OEU19904.1 - 0.32 11.4 4.2 0.72 10.2 4.2 1.7 1 1 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.6 OEU19904.1 - 0.38 10.9 5.6 0.069 13.3 1.8 1.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 OEU19904.1 - 2.2 7.9 7.8 0.16 11.6 2.7 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain RNase_HII PF01351.18 OEU19905.1 - 8.3e-31 107.4 0.0 1.1e-30 107.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII DUF755 PF05501.11 OEU19906.1 - 2.2 8.6 6.5 0.49 10.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FeoB_N PF02421.18 OEU19907.1 - 0.059 12.9 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B PBP1_TM PF14812.6 OEU19908.1 - 7.5 7.0 17.6 0.9 10.0 6.8 2.8 1 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med9 PF07544.13 OEU19910.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cofac_haem_bdg PF04187.13 OEU19911.1 - 1.9e-41 142.4 0.1 2.2e-41 142.2 0.1 1.0 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN DUF445 PF04286.12 OEU19911.1 - 0.13 12.1 0.8 0.17 11.7 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Ribosomal_L18_c PF14204.6 OEU19911.1 - 2.5 9.1 5.6 50 4.9 0.2 3.1 2 1 1 3 3 3 0 Ribosomal L18 C-terminal region Methyltransf_31 PF13847.6 OEU19912.1 - 1.1e-24 87.0 0.1 3.2e-24 85.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19912.1 - 5.2e-21 75.2 0.0 2.4e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU19912.1 - 1.7e-19 70.3 0.0 5.1e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19912.1 - 4.3e-14 52.7 0.0 6.2e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU19912.1 - 3.8e-13 50.0 0.0 6.3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU19912.1 - 1.6e-12 47.3 0.0 2.7e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OEU19912.1 - 6.3e-09 35.6 0.1 1.1e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 OEU19912.1 - 1.1e-08 35.1 0.2 2.1e-08 34.2 0.0 1.6 2 1 0 2 2 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OEU19912.1 - 1.2e-08 34.6 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 OEU19912.1 - 3.2e-07 30.0 0.1 5.2e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OEU19912.1 - 1.7e-05 24.3 0.1 0.0002 20.9 0.1 2.1 2 0 0 2 2 2 1 Putative methyltransferase ADH_zinc_N PF00107.26 OEU19912.1 - 0.00035 20.5 0.0 0.0054 16.7 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FtsJ PF01728.19 OEU19912.1 - 0.0015 18.6 0.0 0.0026 17.9 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OEU19912.1 - 0.0028 17.6 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OEU19912.1 - 0.0032 17.2 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 GCD14 PF08704.10 OEU19912.1 - 0.0051 16.5 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Fibrillarin PF01269.17 OEU19912.1 - 0.0067 15.6 0.0 0.051 12.7 0.0 2.0 2 0 0 2 2 2 1 Fibrillarin NPHI_C PF08469.10 OEU19912.1 - 0.0085 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoside triphosphatase I C-terminal Methyltransf_8 PF05148.15 OEU19912.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase DOT1 PF08123.13 OEU19912.1 - 0.018 14.6 0.1 0.1 12.1 0.1 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 rRNA_methylase PF06962.12 OEU19912.1 - 0.029 14.4 0.1 0.5 10.3 0.1 2.3 1 1 0 1 1 1 0 Putative rRNA methylase Methyltransf_24 PF13578.6 OEU19912.1 - 0.05 14.6 0.0 0.085 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 OEU19912.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ABC_membrane PF00664.23 OEU19913.1 - 4e-49 167.7 31.2 4.6e-28 98.6 14.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU19913.1 - 1.6e-45 155.0 0.1 3.7e-28 98.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OEU19913.1 - 1.3e-09 37.9 0.2 0.001 18.6 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU19913.1 - 6.6e-06 26.2 0.1 0.041 13.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OEU19913.1 - 4.5e-05 23.8 0.1 0.047 14.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU19913.1 - 6.5e-05 23.4 0.9 0.25 11.7 0.6 2.7 2 1 0 2 2 2 2 AAA ATPase domain TsaE PF02367.17 OEU19913.1 - 8.9e-05 22.5 0.1 0.065 13.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OEU19913.1 - 0.00013 21.6 0.1 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU19913.1 - 0.00015 21.7 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 OEU19913.1 - 0.00081 19.3 0.8 3.3 7.4 0.1 3.7 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 OEU19913.1 - 0.0011 18.5 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OEU19913.1 - 0.0068 16.2 0.1 0.31 10.8 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Dynamin_N PF00350.23 OEU19913.1 - 0.0081 16.2 1.0 3.5 7.7 0.1 3.7 4 0 0 4 4 4 1 Dynamin family DUF87 PF01935.17 OEU19913.1 - 0.011 15.8 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 OEU19913.1 - 0.012 14.7 0.1 2.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 OEU19913.1 - 0.013 15.1 0.2 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 OEU19913.1 - 0.014 15.0 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain GTP_EFTU PF00009.27 OEU19913.1 - 0.015 14.9 0.4 5.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DEAD PF00270.29 OEU19913.1 - 0.03 14.1 1.6 0.52 10.1 0.0 2.7 3 0 0 3 3 2 0 DEAD/DEAH box helicase Roc PF08477.13 OEU19913.1 - 0.045 14.0 0.2 8.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 OEU19913.1 - 0.07 12.9 0.2 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 OEU19913.1 - 0.14 11.4 0.2 18 4.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 OEU19913.1 - 0.16 12.1 0.2 36 4.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 OEU19913.1 - 0.18 12.0 0.2 1.3 9.4 0.1 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OEU19913.1 - 0.22 11.2 0.9 2.3 7.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 OEU19913.1 - 0.33 10.7 1.9 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 OEU19913.1 - 0.56 10.7 3.8 6.6 7.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain Orthoreo_P10 PF07204.11 OEU19913.1 - 0.82 9.7 3.4 3.2 7.8 0.2 2.9 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 zf-C3HC4_3 PF13920.6 OEU19914.1 - 3.4e-07 30.0 8.0 3.4e-07 30.0 8.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU19914.1 - 2.1e-05 24.8 10.1 2.1e-05 24.8 10.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OEU19914.1 - 9.1e-05 22.2 9.3 9.1e-05 22.2 9.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU19914.1 - 0.00029 20.6 8.8 0.00029 20.6 8.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU19914.1 - 0.0037 17.2 8.6 0.0037 17.2 8.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain DZR PF12773.7 OEU19914.1 - 0.057 13.5 7.0 2.2 8.3 4.9 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.6 OEU19914.1 - 0.11 12.3 12.1 0.051 13.4 8.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RNA_pol_3_Rpc31 PF11705.8 OEU19915.1 - 0.0015 18.9 14.6 0.0015 18.9 14.6 2.3 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Baculo_PEP_C PF04513.12 OEU19920.1 - 0.011 15.7 2.1 0.011 15.7 2.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 OEU19920.1 - 0.079 13.0 11.4 0.64 10.1 0.4 3.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OEU19920.1 - 0.12 12.2 7.0 0.35 10.7 0.1 3.8 2 1 1 3 3 3 0 Septum formation initiator DUF745 PF05335.13 OEU19920.1 - 0.12 12.1 12.4 0.092 12.5 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ZapB PF06005.12 OEU19920.1 - 0.16 12.5 0.2 0.16 12.5 0.2 3.2 3 1 0 3 3 3 0 Cell division protein ZapB IFT20 PF14931.6 OEU19920.1 - 0.21 11.7 7.4 0.8 9.9 0.7 2.5 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Seryl_tRNA_N PF02403.22 OEU19920.1 - 0.24 11.7 13.6 0.43 10.8 0.4 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Hpt PF01627.23 OEU19920.1 - 0.28 11.5 3.0 1.5 9.1 3.0 2.3 1 1 0 1 1 1 0 Hpt domain Atg14 PF10186.9 OEU19920.1 - 0.44 9.6 11.3 0.28 10.2 6.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OEU19920.1 - 0.63 8.9 15.1 0.62 8.9 9.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein GLE1 PF07817.13 OEU19920.1 - 0.74 9.0 4.0 0.81 8.8 0.2 2.3 1 1 1 2 2 2 0 GLE1-like protein DUF1664 PF07889.12 OEU19920.1 - 1 9.4 6.1 13 5.8 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OEU19920.1 - 1.1 9.5 10.4 3.5 7.8 2.6 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 OEU19920.1 - 3.8 8.1 18.6 0.23 12.0 0.3 3.0 3 0 0 3 3 3 0 Apg6 coiled-coil region Syntaxin_2 PF14523.6 OEU19920.1 - 6.8 7.1 13.8 3.1 8.2 2.2 3.5 1 1 2 3 3 3 0 Syntaxin-like protein Sec34 PF04136.15 OEU19920.1 - 9.5 6.1 8.9 5.7 6.8 1.6 2.8 1 1 0 2 2 2 0 Sec34-like family YabA PF06156.13 OEU19920.1 - 9.8 6.9 12.4 13 6.5 2.7 3.6 3 1 0 3 3 3 0 Initiation control protein YabA OAD_gamma PF04277.13 OEU19921.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pox_EPC_I2-L1 PF12575.8 OEU19921.1 - 0.41 10.9 1.4 5.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 ZZ PF00569.17 OEU19922.1 - 6.2e-08 32.3 6.5 1.7e-07 30.9 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 OEU19922.1 - 6.7e-05 23.1 7.3 6.7e-05 23.1 7.3 2.1 2 0 0 2 2 2 1 C1 domain Cript PF10235.9 OEU19922.1 - 0.00049 20.6 3.7 0.0013 19.3 3.7 1.7 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT FYVE PF01363.21 OEU19922.1 - 0.0018 18.4 0.5 0.0018 18.4 0.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger DUF4710 PF15828.5 OEU19922.1 - 0.86 9.8 9.7 0.68 10.1 4.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) TSGP1 PF07771.11 OEU19922.1 - 1.9 8.7 14.4 0.67 10.1 5.0 2.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 Ferlin_C PF16165.5 OEU19922.1 - 3.7 7.5 9.4 3.5 7.6 2.3 2.7 3 0 0 3 3 3 0 Ferlin C-terminus GEN1_C PF18380.1 OEU19922.1 - 8.9 7.3 8.7 14 6.6 1.3 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain ABC1 PF03109.16 OEU19926.1 - 9.6e-21 74.2 0.0 1.8e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family DUF4637 PF15470.6 OEU19928.1 - 0.12 12.1 0.2 2.9 7.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4637) Calponin PF00402.18 OEU19928.1 - 0.71 9.6 3.2 10 5.9 0.3 2.3 2 0 0 2 2 2 0 Calponin family repeat UPF0029 PF01205.19 OEU19929.1 - 7.1e-12 45.6 0.3 7.1e-12 45.6 0.3 2.1 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF2971 PF11185.8 OEU19929.1 - 0.046 14.9 7.5 0.094 13.9 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) DUF913 PF06025.12 OEU19929.1 - 0.066 12.2 1.4 0.08 11.9 1.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Menin PF05053.13 OEU19929.1 - 0.077 11.4 5.2 0.097 11.0 5.2 1.2 1 0 0 1 1 1 0 Menin O-antigen_lig PF13425.6 OEU19929.1 - 0.23 10.2 1.4 0.32 9.7 1.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SDA1 PF05285.12 OEU19929.1 - 0.42 10.0 13.0 0.61 9.4 13.0 1.3 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 OEU19929.1 - 0.57 8.9 2.4 0.61 8.8 2.4 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OEU19929.1 - 0.65 9.2 3.9 0.78 8.9 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OEU19929.1 - 0.84 8.4 6.7 1 8.1 6.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2457 PF10446.9 OEU19929.1 - 0.94 8.5 14.4 1.1 8.3 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-I PF07778.11 OEU19929.1 - 3.7 6.2 7.0 1.7 7.3 4.3 1.8 1 1 1 2 2 2 0 Mis6 Ysc84 PF04366.12 OEU19931.1 - 8.6e-31 106.3 0.1 1.6e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator PX PF00787.24 OEU19931.1 - 6.5e-06 26.1 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF1479 PF07350.12 OEU19931.1 - 0.064 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Sulfatase PF00884.23 OEU19932.1 - 8.7e-39 133.7 0.0 1.2e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase CBM_35 PF16990.5 OEU19932.1 - 0.0001 22.5 0.1 0.00022 21.5 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF4983 PF16356.5 OEU19932.1 - 0.02 15.7 0.3 0.093 13.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4983) Phosphodiest PF01663.22 OEU19932.1 - 0.08 12.5 1.1 0.45 10.0 0.0 2.3 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase Endotoxin_C PF03944.14 OEU19932.1 - 0.081 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 delta endotoxin DUF3592 PF12158.8 OEU19933.1 - 0.62 10.1 2.6 14 5.7 1.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) NAD_kinase PF01513.21 OEU19935.1 - 1.6e-41 142.4 0.1 2.2e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase ETF_QO PF05187.13 OEU19936.1 - 8.1e-21 74.1 1.2 8.5e-21 74.0 1.2 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ACBP PF00887.19 OEU19937.1 - 1.5e-15 57.2 0.4 1.5e-15 57.2 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Tudor-knot PF11717.8 OEU19939.1 - 3e-05 23.8 0.1 5.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Nha1_C PF08619.10 OEU19939.1 - 0.0069 15.7 2.5 0.0097 15.2 2.5 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Peptidase_M99_C PF17129.4 OEU19939.1 - 0.02 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of metallo-carboxypeptidase Chromo PF00385.24 OEU19939.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 OEU19940.1 - 3.9e-06 26.7 0.5 4.7e-06 26.4 0.5 1.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OEU19940.1 - 0.15 11.6 3.3 2 8.1 0.2 2.2 2 0 0 2 2 2 0 PHD-finger LRR_8 PF13855.6 OEU19941.1 - 5.1e-07 29.4 18.9 0.0011 18.7 8.1 3.5 2 2 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OEU19941.1 - 3.9e-05 23.9 25.8 0.0049 17.3 5.0 5.9 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU19941.1 - 0.081 13.5 7.6 1.9 9.3 0.8 5.3 6 1 1 7 7 7 0 Leucine Rich Repeat HEPN_AbiU2 PF18734.1 OEU19942.1 - 0.037 13.5 0.3 0.037 13.5 0.3 1.8 1 1 1 2 2 2 0 AbiU2 Rotamase_3 PF13616.6 OEU19944.1 - 3.5e-13 50.1 0.0 4.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OEU19944.1 - 4e-13 50.1 0.0 5.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU19944.1 - 3.3e-05 24.7 0.0 4.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain IHO1 PF15771.5 OEU19945.1 - 0.00061 18.7 3.6 0.00078 18.3 3.6 1.1 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 SHS2_Rpb7-N PF03876.17 OEU19946.1 - 4.5e-08 33.4 0.1 8.5e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OEU19946.1 - 2.9e-07 30.7 0.0 7.7e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OEU19946.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 FKBP_C PF00254.28 OEU19947.1 - 2.4e-29 101.5 0.0 7.7e-29 99.9 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 OEU19947.1 - 4.1e-06 27.6 0.0 6.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HEAT PF02985.22 OEU19948.1 - 7.9 7.0 6.1 21 5.7 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat Glutaredoxin PF00462.24 OEU19949.1 - 4.9e-18 65.1 0.0 7.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 OEU19949.1 - 0.02 15.2 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU19949.1 - 0.033 14.6 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 OEU19949.1 - 0.078 13.4 0.0 0.3 11.6 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain Rubis-subs-bind PF09273.11 OEU19950.1 - 8.4e-10 39.4 0.0 1.6e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OEU19950.1 - 6.7e-08 33.1 0.0 1.4e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 SET domain Methyltransf_11 PF08241.12 OEU19951.1 - 2e-06 28.4 0.0 4.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU19951.1 - 3.1e-05 24.6 0.0 8.6e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19951.1 - 0.00014 22.5 0.0 0.0024 18.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU19951.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19951.1 - 0.0084 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CENP-B_dimeris PF09026.10 OEU19951.1 - 1 9.8 6.3 12 6.4 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Methyltransf_11 PF08241.12 OEU19952.1 - 1.8e-10 41.3 0.0 4.4e-10 40.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU19952.1 - 8e-08 31.9 0.0 9.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU19952.1 - 6.9e-06 26.7 0.0 2.5e-05 25.0 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU19952.1 - 1.1e-05 25.4 0.0 1.3e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU19952.1 - 2.2e-05 25.1 0.0 0.00014 22.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU19952.1 - 0.00012 21.9 0.1 0.00019 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OEU19952.1 - 0.00066 19.3 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 OEU19952.1 - 0.0033 17.2 0.0 0.017 14.9 0.0 1.8 1 1 0 2 2 2 1 DNA methylase VCPO_N PF17897.1 OEU19952.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain Methyltransf_8 PF05148.15 OEU19952.1 - 0.097 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase TPR_8 PF13181.6 OEU19953.1 - 2.1e-05 24.4 0.1 0.037 14.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19953.1 - 5.4e-05 22.8 0.4 0.047 13.5 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19953.1 - 0.00043 20.2 3.4 0.023 14.8 1.6 2.5 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU19953.1 - 0.0011 19.2 0.6 0.62 10.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apis_Csd PF11671.8 OEU19954.1 - 0.00024 21.1 2.7 0.00032 20.7 2.7 1.1 1 0 0 1 1 1 1 Complementary sex determiner protein NPR3 PF03666.13 OEU19954.1 - 0.059 12.1 5.5 0.063 12.1 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 OEU19954.1 - 1.8 7.0 7.5 1.8 7.0 7.5 1.1 1 0 0 1 1 1 0 Macoilin family SMYLE_N PF18615.1 OEU19954.1 - 2.5 7.6 5.7 2.9 7.3 5.7 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 OEU19954.1 - 5.8 5.6 7.5 6.7 5.4 7.5 1.1 1 0 0 1 1 1 0 Presenilin 2OG-FeII_Oxy_3 PF13640.6 OEU19955.1 - 6.5e-07 30.1 0.0 2.6e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Syntaxin_2 PF14523.6 OEU19956.1 - 0.02 15.3 1.7 0.053 13.9 1.7 1.6 1 0 0 1 1 1 0 Syntaxin-like protein DUF559 PF04480.12 OEU19956.1 - 0.053 13.4 1.1 13 5.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF559) AAA_13 PF13166.6 OEU19956.1 - 0.1 11.2 5.2 0.15 10.7 5.2 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_C65 PF10275.9 OEU19956.1 - 0.14 11.6 0.7 0.27 10.6 0.7 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain DUF883 PF05957.13 OEU19956.1 - 0.21 12.2 5.4 0.22 12.2 1.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA_11 PF13086.6 OEU19956.1 - 0.24 11.2 2.6 0.36 10.6 2.6 1.2 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 OEU19956.1 - 0.44 9.0 7.6 0.85 8.1 7.6 1.3 1 0 0 1 1 1 0 Macoilin family Myb_DNA-bind_4 PF13837.6 OEU19956.1 - 0.89 10.0 6.1 0.21 12.0 0.5 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain CCDC-167 PF15188.6 OEU19956.1 - 4.9 7.6 8.1 2.5 8.5 0.4 3.2 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 LRR_4 PF12799.7 OEU19958.1 - 8.8e-08 32.3 8.9 0.00032 21.0 0.3 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU19958.1 - 2.2e-07 30.5 4.2 0.00031 20.4 0.1 2.9 1 1 2 3 3 3 3 Leucine rich repeat Josephin PF02099.17 OEU19959.1 - 4.7e-11 43.0 0.0 1.3e-09 38.4 0.0 2.0 1 1 0 1 1 1 1 Josephin DUF3275 PF11679.8 OEU19960.1 - 0.19 11.7 0.8 0.41 10.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ank_5 PF13857.6 OEU19961.1 - 4.8e-10 39.5 0.8 2.3e-07 30.9 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU19961.1 - 2.9e-06 27.8 0.1 0.00011 22.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU19961.1 - 0.0012 19.4 0.1 0.02 15.5 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) IFP_35_N PF07334.13 OEU19961.1 - 0.054 13.6 3.4 0.16 12.1 3.4 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ank PF00023.30 OEU19961.1 - 0.1 13.1 1.2 6.3 7.4 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 OEU19961.1 - 0.1 13.2 3.5 33 5.5 0.1 3.9 4 0 0 4 4 4 0 Ankyrin repeat PBP1_TM PF14812.6 OEU19961.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MDM10 PF12519.8 OEU19961.1 - 0.42 9.4 7.1 0.92 8.3 7.1 1.7 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 XRCC4 PF06632.12 OEU19962.1 - 0.031 13.1 0.2 0.04 12.8 0.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF202 PF02656.15 OEU19963.1 - 4.8e-16 58.9 0.9 5.9e-16 58.7 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF202 PF02656.15 OEU19964.1 - 1.2e-12 48.1 0.3 2.1e-12 47.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) RXLR PF16810.5 OEU19966.1 - 0.085 13.3 0.0 0.097 13.1 0.0 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity tRNA-synt_2b PF00587.25 OEU19967.1 - 1.9e-30 106.2 0.0 2.9e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OEU19967.1 - 1.8 8.8 6.6 0.19 12.0 2.3 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain VIT1 PF01988.19 OEU19968.1 - 4.5e-11 43.0 3.6 5.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 VIT family Wzy_C_2 PF11846.8 OEU19968.1 - 0.65 9.9 1.9 0.72 9.7 0.0 1.9 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal UQ_con PF00179.26 OEU19969.1 - 2e-36 124.7 0.0 2.5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OEU19969.1 - 0.022 14.6 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 OEU19969.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 OEU19969.1 - 0.062 13.6 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 RWD domain Sigma70_ner PF04546.13 OEU19970.1 - 0.017 15.0 0.6 0.022 14.6 0.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 OEU19970.1 - 0.077 11.5 1.8 0.098 11.2 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PDDEXK_1 PF12705.7 OEU19971.1 - 1.7e-21 77.3 3.2 2.1e-19 70.4 3.2 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 OEU19971.1 - 0.00078 18.8 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2800) Dna2 PF08696.11 OEU19971.1 - 0.021 14.6 0.9 0.021 14.6 0.9 2.4 2 1 0 2 2 2 0 DNA replication factor Dna2 SUIM_assoc PF16619.5 OEU19971.1 - 0.025 14.6 10.8 0.26 11.4 2.0 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_C10 PF01640.17 OEU19971.1 - 1 9.6 9.9 2.3 8.5 2.0 2.4 2 1 0 2 2 2 0 Peptidase C10 family Herpes_capsid PF06112.11 OEU19971.1 - 2.2 8.3 11.2 5.3 7.1 11.2 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CPSF100_C PF13299.6 OEU19971.1 - 2.7 8.1 10.5 5.7 7.1 0.2 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Shugoshin_C PF07557.11 OEU19972.1 - 5.9e-09 35.6 1.4 2.3e-08 33.7 1.4 2.1 1 0 0 1 1 1 1 Shugoshin C terminus DUF4407 PF14362.6 OEU19972.1 - 0.72 9.2 11.5 1.8 7.8 11.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Plexin_cytopl PF08337.12 OEU19972.1 - 2.1 6.9 11.4 4.9 5.7 11.4 1.5 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Pyrid_oxidase_2 PF13883.6 OEU19973.1 - 2.1e-24 86.4 0.0 3.6e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 OEU19973.1 - 2.4e-07 31.3 0.1 6.8e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 OEU19973.1 - 0.0051 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sec7 PF01369.20 OEU19974.1 - 1e-68 230.6 0.4 3.5e-67 225.6 0.0 3.0 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 OEU19974.1 - 8.4e-34 116.8 7.0 1.7e-33 115.7 1.5 3.4 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OEU19974.1 - 6.8e-19 67.5 0.0 2e-16 59.6 0.0 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) DCB PF16213.5 OEU19974.1 - 0.0015 18.2 2.6 0.0047 16.6 0.3 3.1 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 PPTA PF01239.22 OEU19975.1 - 8.5e-31 104.8 11.8 6.1e-08 32.1 0.1 5.7 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat MVL PF12151.8 OEU19975.1 - 0.0074 16.1 0.6 0.02 14.7 0.6 1.8 1 0 0 1 1 1 1 Mannan-binding protein Ndc1_Nup PF09531.10 OEU19975.1 - 0.14 10.8 6.1 0.22 10.2 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SUIM_assoc PF16619.5 OEU19975.1 - 0.47 10.6 22.9 0.064 13.3 10.8 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SID-1_RNA_chan PF13965.6 OEU19975.1 - 2.1 6.6 8.6 0.18 10.2 2.8 2.0 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 MBOAT_2 PF13813.6 OEU19977.1 - 7.2e-13 48.6 0.3 1.9e-12 47.3 0.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family McyA_C PF12593.8 OEU19977.1 - 0.15 11.8 0.9 0.91 9.4 0.4 2.5 2 0 0 2 2 2 0 Microcystin synthetase C terminal Phage_holin_3_3 PF16083.5 OEU19977.1 - 0.27 11.4 3.2 0.18 11.9 0.4 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III FeoB_associated PF12669.7 OEU19977.1 - 0.62 10.5 3.9 1.2 9.6 1.5 2.5 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DnaJ PF00226.31 OEU19978.1 - 7.9e-22 77.2 4.1 9.3e-22 76.9 4.1 1.1 1 0 0 1 1 1 1 DnaJ domain rve PF00665.26 OEU19979.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DPRP PF04244.13 OEU19979.1 - 0.048 13.5 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein PUB PF09409.10 OEU19980.1 - 1e-11 44.6 0.0 2.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 PUB domain VHL PF01847.16 OEU19980.1 - 8.5e-06 25.6 0.4 1.7e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 VHL beta domain Hist_deacetyl PF00850.19 OEU19981.1 - 7e-59 199.8 0.0 9.4e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TRL PF13146.6 OEU19981.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 TRL-like protein family Kinesin PF00225.23 OEU19982.1 - 2.3e-102 342.3 0.1 2.7e-102 342.1 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU19982.1 - 4.1e-22 78.7 0.0 1.1e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 OEU19982.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein PIF1 PF05970.14 OEU19982.1 - 0.043 13.0 1.0 0.47 9.6 0.3 2.3 2 0 0 2 2 2 0 PIF1-like helicase zinc_ribbon_6 PF14599.6 OEU19983.1 - 0.13 12.2 2.1 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-ribbon ALIX_LYPXL_bnd PF13949.6 OEU19984.1 - 1.4e-25 90.2 8.7 2.2e-25 89.6 8.7 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV UBA PF00627.31 OEU19984.1 - 2.4e-08 33.7 0.0 4.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 OEU19984.1 - 0.00042 20.1 1.3 0.0035 17.1 1.3 2.4 1 1 0 1 1 1 1 Fungal ubiquitin-associated domain DNA_Packaging_2 PF11123.8 OEU19984.1 - 0.0029 17.8 0.2 0.26 11.5 0.0 3.0 2 0 0 2 2 2 1 DNA packaging protein DUF1043 PF06295.12 OEU19984.1 - 0.034 14.2 5.4 0.85 9.6 0.0 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1043) UBA_4 PF14555.6 OEU19984.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 OEU19984.1 - 0.072 12.8 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 CUE domain CC2-LZ PF16516.5 OEU19984.1 - 0.64 10.4 5.5 0.29 11.5 0.2 3.0 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator UBA_2 PF08587.11 OEU19984.1 - 1 9.5 3.9 1.5 9.0 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) UIM PF02809.20 OEU19985.1 - 0.0095 15.8 3.7 0.031 14.2 3.7 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif CLN3 PF02487.17 OEU19986.1 - 9.7e-72 242.2 10.4 1.9e-48 165.5 0.1 4.0 1 1 2 3 3 3 2 CLN3 protein FA_desaturase PF00487.24 OEU19986.1 - 0.059 13.2 5.9 0.41 10.5 0.2 3.3 3 0 0 3 3 3 0 Fatty acid desaturase SID-1_RNA_chan PF13965.6 OEU19986.1 - 10 4.4 14.0 1.6 7.0 5.4 2.5 2 1 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1180 PF06679.12 OEU19987.1 - 0.00018 22.0 0.3 0.00018 22.0 0.3 3.9 5 1 0 5 5 5 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 OEU19987.1 - 0.018 15.9 0.0 1.6 9.6 0.0 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OSTbeta PF15048.6 OEU19987.1 - 0.027 14.6 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TMEM51 PF15345.6 OEU19987.1 - 0.039 13.8 0.0 0.039 13.8 0.0 3.3 3 0 0 3 3 3 0 Transmembrane protein 51 PT PF04886.12 OEU19987.1 - 0.89 9.2 62.3 1 8.9 1.1 5.0 1 1 1 2 2 2 0 PT repeat ATP-synt_C PF00137.21 OEU19989.1 - 1.3e-11 44.7 23.8 2.3e-05 24.7 4.3 3.4 3 0 0 3 3 3 3 ATP synthase subunit C F420_oxidored PF03807.17 OEU19990.1 - 1.1e-05 25.9 0.1 0.00022 21.7 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 OEU19990.1 - 0.00027 20.5 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 OEU19990.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OEU19990.1 - 0.038 13.9 0.5 0.071 13.0 0.1 1.8 2 0 0 2 2 2 0 KR domain NAD_binding_7 PF13241.6 OEU19990.1 - 0.052 14.0 0.0 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF4191 PF13829.6 OEU19991.1 - 0.18 11.1 0.9 0.35 10.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) TPR_14 PF13428.6 OEU19992.1 - 3.6e-21 74.0 15.8 0.0034 18.1 0.1 10.3 6 4 5 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 OEU19992.1 - 4.4e-19 67.0 14.7 0.7 10.2 0.0 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 OEU19992.1 - 1.7e-18 66.9 2.7 0.0013 19.2 0.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 OEU19992.1 - 2.8e-13 49.9 25.3 0.0062 16.8 0.4 8.3 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 OEU19992.1 - 2.8e-12 46.1 0.9 0.48 10.9 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU19992.1 - 1.4e-11 43.7 1.1 0.044 13.6 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU19992.1 - 2.9e-11 42.8 2.2 0.00098 18.8 0.0 6.7 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.6 OEU19992.1 - 2.1e-10 41.1 17.2 0.0016 19.1 0.4 6.3 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU19992.1 - 3.8e-10 39.2 8.8 0.23 11.8 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU19992.1 - 9.4e-10 38.4 6.0 7.6e-06 25.5 0.8 4.8 3 1 2 5 5 5 3 MalT-like TPR region SAP PF02037.27 OEU19992.1 - 1.7e-07 30.8 1.8 3.9e-07 29.7 1.8 1.6 1 0 0 1 1 1 1 SAP domain Mad3_BUB1_I PF08311.12 OEU19992.1 - 0.00011 22.2 5.3 13 5.7 0.1 6.6 7 1 0 7 7 7 0 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 OEU19992.1 - 0.014 15.6 7.1 8 6.7 0.2 4.9 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU19992.1 - 0.095 12.6 0.2 0.095 12.6 0.2 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 OEU19992.1 - 0.14 12.8 15.0 0.5 11.1 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 OEU19992.1 - 0.15 12.0 6.8 0.098 12.6 0.2 3.1 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) DUF3110 PF11360.8 OEU19993.1 - 8.3e-10 38.7 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) TatD_DNase PF01026.21 OEU19994.1 - 3.2e-42 144.7 0.0 6.4e-42 143.7 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Radical_SAM PF04055.21 OEU19994.1 - 0.033 14.6 0.2 5 7.5 0.0 3.1 2 1 1 3 3 3 0 Radical SAM superfamily Glyco_hydro_57 PF03065.15 OEU19994.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Methyltransf_22 PF13383.6 OEU19996.1 - 2.3e-30 106.0 0.6 6.6e-21 75.0 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain RepB PF07506.11 OEU19997.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein AP-5_subunit_s1 PF15001.6 OEU19997.1 - 0.1 12.6 1.4 0.18 11.8 1.4 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 P_proprotein PF01483.20 OEU19997.1 - 9.1 6.4 10.7 0.45 10.6 0.2 2.9 2 2 2 4 4 4 0 Proprotein convertase P-domain La PF05383.17 OEU19998.1 - 5.1e-15 55.3 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 La domain WD40 PF00400.32 OEU19999.1 - 0.00026 21.7 0.5 0.0037 18.1 0.1 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat BUD22 PF09073.10 OEU19999.1 - 0.0062 15.9 16.8 0.0062 15.9 16.8 1.8 2 0 0 2 2 2 1 BUD22 Drc1-Sld2 PF11719.8 OEU19999.1 - 0.02 14.5 11.6 0.026 14.1 11.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Herpes_UL32 PF06070.11 OEU19999.1 - 0.03 12.1 6.3 0.04 11.7 6.3 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Apt1 PF10351.9 OEU19999.1 - 0.044 12.7 7.4 0.046 12.6 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nucleoporin_N PF08801.11 OEU19999.1 - 0.056 12.2 0.1 0.066 11.9 0.1 1.4 1 1 0 1 1 1 0 Nup133 N terminal like MCM_bind PF09739.9 OEU19999.1 - 0.15 10.5 3.4 0.19 10.2 3.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 OEU19999.1 - 0.25 10.1 6.0 0.28 9.9 6.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 OEU19999.1 - 0.38 10.1 22.8 0.015 14.8 13.9 1.9 2 0 0 2 2 2 0 SDA1 Presenilin PF01080.17 OEU19999.1 - 0.41 9.3 2.7 0.55 8.9 2.7 1.2 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 OEU19999.1 - 0.58 8.5 1.1 0.72 8.2 1.1 1.1 1 0 0 1 1 1 0 Membrane transport protein RNA_pol_Rpc4 PF05132.14 OEU19999.1 - 0.6 10.5 5.0 0.088 13.2 1.6 1.4 2 0 0 2 2 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 OEU19999.1 - 1.1 7.5 21.4 0.015 13.6 13.5 1.6 2 0 0 2 2 2 0 CDC45-like protein ANAPC15 PF15243.6 OEU19999.1 - 1.6 9.2 21.7 12 6.4 0.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Vfa1 PF08432.10 OEU19999.1 - 1.8 8.9 15.0 0.12 12.7 10.1 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4637 PF15470.6 OEU19999.1 - 2.3 7.9 12.0 0.066 12.9 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PRP1_N PF06424.12 OEU19999.1 - 2.4 8.5 16.2 0.52 10.7 9.0 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal CCDC106 PF15794.5 OEU19999.1 - 6 6.5 12.0 11 5.6 12.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GST_N_3 PF13417.6 OEU20000.1 - 4.8e-07 30.1 2.5 0.3 11.5 0.0 3.4 2 2 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU20000.1 - 0.066 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin AAA PF00004.29 OEU20002.1 - 5.4e-16 59.2 0.0 1e-15 58.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OEU20002.1 - 1.2e-12 47.9 0.0 1.3e-09 38.1 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OEU20002.1 - 2.5e-10 40.6 0.0 1.4e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 OEU20002.1 - 2.3e-07 31.1 0.0 5.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.12 OEU20002.1 - 7.6e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OEU20002.1 - 9e-05 22.7 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 OEU20002.1 - 0.00013 21.8 0.1 0.00042 20.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 OEU20002.1 - 0.00015 21.6 0.0 0.00055 19.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU20002.1 - 0.0002 21.4 0.5 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU20002.1 - 0.00021 21.6 0.5 0.1 12.9 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU20002.1 - 0.00023 21.6 0.0 0.00051 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OEU20002.1 - 0.0003 20.6 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU20002.1 - 0.00053 20.3 0.2 0.0085 16.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 OEU20002.1 - 0.00096 19.1 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OEU20002.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OEU20002.1 - 0.0022 17.5 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 OEU20002.1 - 0.0027 16.9 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 OEU20002.1 - 0.0046 17.0 0.0 0.19 11.7 0.0 2.2 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 OEU20002.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DNA_pol3_delta PF06144.13 OEU20002.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 OEU20002.1 - 0.028 14.9 0.0 0.08 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 OEU20002.1 - 0.033 14.0 0.2 0.32 10.7 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 OEU20002.1 - 0.036 13.5 0.1 0.2 11.1 0.1 2.0 1 1 1 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 OEU20002.1 - 0.046 13.2 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein MCM PF00493.23 OEU20002.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SNF2_N PF00176.23 OEU20002.1 - 0.11 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Mg_chelatase PF01078.21 OEU20002.1 - 0.16 11.3 0.2 0.5 9.7 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI PAP_fibrillin PF04755.12 OEU20003.1 - 5.1e-18 65.7 0.1 4e-12 46.5 0.0 2.1 1 1 1 2 2 2 2 PAP_fibrillin PseudoU_synth_2 PF00849.22 OEU20004.1 - 1.5e-26 93.4 0.0 2.9e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Pro_isomerase PF00160.21 OEU20005.1 - 1.6e-44 152.0 0.1 2.1e-44 151.6 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PBP1_TM PF14812.6 OEU20006.1 - 1.8e-05 25.0 1.0 0.38 11.2 0.0 3.6 3 0 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal GRP PF07172.11 OEU20006.1 - 0.12 13.1 1.2 1.4 9.7 0.0 3.0 4 0 0 4 4 4 0 Glycine rich protein family ETRAMP PF09716.10 OEU20006.1 - 0.61 10.2 4.4 26 4.9 4.4 2.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Asp_Arg_Hydrox PF05118.15 OEU20007.1 - 6.9e-35 120.2 0.0 8.8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF2956 PF11169.8 OEU20009.1 - 0.0064 16.7 2.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2956) DUF4633 PF15464.6 OEU20009.1 - 0.068 13.3 3.1 0.23 11.6 0.4 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4633) LapA_dom PF06305.11 OEU20009.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3246 PF11596.8 OEU20009.1 - 0.13 11.6 2.2 0.2 11.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) UCH PF00443.29 OEU20010.1 - 2e-38 132.3 0.2 3.4e-33 115.2 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU20010.1 - 5e-14 52.6 1.9 1.4e-12 47.8 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_2 PF13240.6 OEU20010.1 - 0.11 12.2 1.0 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Tudor_4 PF18358.1 OEU20010.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain zf-CCHC_3 PF13917.6 OEU20010.1 - 1.7 8.7 5.0 12 6.0 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle ABC_tran PF00005.27 OEU20011.1 - 7.3e-06 26.5 0.0 7.3e-06 26.5 0.0 3.4 3 1 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 OEU20011.1 - 0.05 14.0 0.1 1 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain BUD22 PF09073.10 OEU20012.1 - 0.055 12.8 3.3 0.087 12.1 3.3 1.4 1 1 0 1 1 1 0 BUD22 FAM176 PF14851.6 OEU20012.1 - 8.6 6.0 11.1 8.8 6.0 5.7 2.3 2 0 0 2 2 2 0 FAM176 family GCIP PF13324.6 OEU20013.1 - 0.036 13.7 2.1 0.047 13.3 2.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF913 PF06025.12 OEU20013.1 - 0.045 12.7 1.6 0.057 12.4 1.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MazG-like PF12643.7 OEU20013.1 - 0.06 13.6 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 MazG-like family Yae1_N PF09811.9 OEU20013.1 - 0.062 13.0 2.5 0.12 12.1 2.5 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Sigma70_ner PF04546.13 OEU20013.1 - 0.16 11.9 11.0 0.28 11.0 11.0 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 OEU20013.1 - 0.23 9.5 8.3 0.24 9.4 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 OEU20013.1 - 0.43 10.8 8.8 1.4 9.2 8.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) MMgT PF10270.9 OEU20016.1 - 0.088 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Membrane magnesium transporter UPF0203 PF05254.12 OEU20017.1 - 2.9e-08 33.9 3.7 2.9e-08 33.9 3.7 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 OEU20017.1 - 0.0024 17.9 3.6 0.06 13.5 0.3 2.4 2 0 0 2 2 2 2 CHCH domain TarS_C1 PF18674.1 OEU20017.1 - 0.02 14.8 0.8 0.026 14.5 0.8 1.1 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 CDC45 PF02724.14 OEU20017.1 - 0.084 11.2 5.1 0.11 10.8 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Cmc1 PF08583.10 OEU20017.1 - 0.097 12.7 8.0 0.22 11.5 0.4 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like SR-25 PF10500.9 OEU20017.1 - 3.7 7.1 17.8 9.5 5.8 17.8 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDP-OH_P_transf PF01066.21 OEU20018.1 - 5.4e-14 52.7 0.3 5.4e-14 52.7 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cpn60_TCP1 PF00118.24 OEU20019.1 - 3.3e-160 534.0 0.9 3.7e-160 533.8 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEAD PF00270.29 OEU20020.1 - 3.1e-20 72.7 0.0 5.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU20020.1 - 7.9e-14 51.9 0.2 3.8e-13 49.8 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU20020.1 - 4.3e-08 33.4 0.0 1.4e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OEU20020.1 - 0.00096 18.0 0.1 0.0024 16.7 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Pilin_GH PF16734.5 OEU20020.1 - 0.048 14.0 0.1 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative Peptidase_M20 PF01546.28 OEU20021.1 - 1.1e-35 123.2 0.1 1.6e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OEU20021.1 - 1.9e-13 50.3 0.0 4.8e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Kelch_4 PF13418.6 OEU20021.1 - 0.011 15.7 0.2 0.09 12.8 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain DSBA PF01323.20 OEU20022.1 - 2.2e-26 92.8 0.0 2.5e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 OEU20022.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OEU20022.1 - 0.008 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain SNARE_assoc PF09335.11 OEU20024.1 - 2.6e-08 34.3 3.3 2.6e-08 34.3 3.3 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Bax1-I PF01027.20 OEU20024.1 - 0.48 10.2 4.6 3.6 7.4 4.6 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Thioredoxin_8 PF13905.6 OEU20025.1 - 9.3e-36 122.0 0.0 2.6e-19 69.3 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.6 OEU20025.1 - 0.001 19.0 0.3 0.0072 16.3 0.0 2.5 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OEU20025.1 - 0.0013 19.1 0.0 0.034 14.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU20025.1 - 0.0017 18.3 0.1 0.021 14.7 0.0 2.5 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OEU20025.1 - 0.012 15.3 0.0 0.045 13.5 0.0 1.8 1 1 0 1 1 1 0 Redoxin CRAL_TRIO_2 PF13716.6 OEU20025.1 - 0.012 15.7 0.2 1.9 8.7 0.0 2.8 3 0 0 3 3 3 0 Divergent CRAL/TRIO domain Thioredoxin_7 PF13899.6 OEU20025.1 - 0.014 15.5 0.1 1.6 9.0 0.1 2.7 2 2 0 2 2 2 0 Thioredoxin-like Thioredoxin PF00085.20 OEU20025.1 - 0.029 14.4 0.0 1.9 8.5 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin DUF705 PF05152.12 OEU20025.1 - 0.035 13.6 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Peptidase_S9 PF00326.21 OEU20026.1 - 5.8e-45 153.4 0.2 9e-45 152.7 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 OEU20026.1 - 2.6e-09 36.4 5.7 0.00075 18.4 2.3 3.0 2 1 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain DnaJ-X PF14308.6 OEU20027.1 - 1.1e-31 110.0 0.6 3.6e-31 108.2 0.4 1.9 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 OEU20027.1 - 8.8e-16 57.8 0.3 1.8e-15 56.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 OEU20028.1 - 2.7e-36 125.0 6.2 4.3e-36 124.3 6.2 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 OEU20028.1 - 3.1e-22 78.5 4.6 3.1e-22 78.5 4.6 2.1 2 0 0 2 2 2 1 DnaJ domain PC-Esterase PF13839.6 OEU20029.1 - 1.6e-13 51.1 0.2 2.5e-06 27.5 0.1 3.9 1 1 1 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p XPG_N PF00752.17 OEU20030.1 - 8.7e-31 106.4 0.0 2.2e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OEU20030.1 - 2.8e-28 98.1 0.1 2.8e-28 98.1 0.1 2.1 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 OEU20030.1 - 8.4e-08 32.7 2.4 1.6e-07 31.8 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 OEU20030.1 - 2.2e-05 24.0 0.1 2.2e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus 5_3_exonuc_N PF02739.16 OEU20030.1 - 0.0004 20.3 0.0 0.0015 18.4 0.0 2.0 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 OEU20030.1 - 0.0018 18.9 0.0 0.0057 17.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 OEU20030.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Bac_luciferase PF00296.20 OEU20030.1 - 0.51 9.7 2.4 0.25 10.7 0.3 1.6 2 0 0 2 2 2 0 Luciferase-like monooxygenase LRR_6 PF13516.6 OEU20031.1 - 0.44 10.7 7.0 20 5.5 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 OEU20031.1 - 0.53 10.8 10.3 3.9 8.0 0.1 5.3 2 2 5 7 7 7 0 Leucine Rich repeats (2 copies) RNA_pol_Rpb8 PF03870.15 OEU20032.1 - 6.4e-44 149.5 0.0 7.2e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OEU20032.1 - 1.4e-05 25.1 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G BTB PF00651.31 OEU20033.1 - 1.3e-08 35.0 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 OEU20033.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) ATP-synt_C PF00137.21 OEU20034.1 - 5e-37 126.0 10.4 3.1e-21 75.5 0.1 2.4 2 1 0 2 2 2 2 ATP synthase subunit C DUF4577 PF15145.6 OEU20034.1 - 0.06 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) TMEM154 PF15102.6 OEU20034.1 - 0.17 11.8 0.3 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family ATP-synt_C PF00137.21 OEU20035.1 - 1.8e-37 127.5 17.6 2e-23 82.5 5.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ank_5 PF13857.6 OEU20036.1 - 5.7e-06 26.5 0.2 5.8e-05 23.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU20036.1 - 1.7e-05 25.2 0.0 0.00016 22.2 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU20036.1 - 0.00025 21.6 0.5 0.054 14.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU20036.1 - 0.0089 16.4 0.2 1.3 9.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OEU20036.1 - 0.022 15.2 0.0 1.6 9.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Glutaredoxin PF00462.24 OEU20037.1 - 0.00014 22.0 0.1 0.00082 19.5 0.0 2.3 2 1 0 2 2 2 1 Glutaredoxin Snf7 PF03357.21 OEU20038.1 - 3.7e-19 69.0 14.8 3.7e-19 69.0 14.8 2.0 2 0 0 2 2 2 1 Snf7 DUF3152 PF11350.8 OEU20038.1 - 0.074 12.7 0.3 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) UPF1_Zn_bind PF09416.10 OEU20041.1 - 3.1e-61 205.8 4.2 3.3e-61 205.7 3.1 1.6 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 OEU20041.1 - 6e-26 91.8 0.8 4.7e-17 62.6 0.2 2.2 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 OEU20041.1 - 2.6e-20 72.9 0.0 5.5e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF5599 PF18141.1 OEU20041.1 - 2.3e-16 59.8 0.0 6.9e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OEU20041.1 - 1.4e-11 44.5 0.1 2.3e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU20041.1 - 7.5e-10 39.3 0.1 2.4e-08 34.4 0.1 2.7 3 0 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 OEU20041.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Helicase ResIII PF04851.15 OEU20041.1 - 0.00018 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OEU20041.1 - 0.00078 19.0 0.1 0.0036 16.8 0.1 1.9 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 OEU20041.1 - 0.0022 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OEU20041.1 - 0.0023 17.5 0.1 0.004 16.7 0.1 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 OEU20041.1 - 0.0034 17.2 0.1 0.0062 16.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 OEU20041.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 OEU20041.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OEU20041.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OEU20041.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_S13_N PF08069.12 OEU20041.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.6 OEU20041.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OEU20041.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 OEU20041.1 - 0.16 11.5 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OEU20041.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 OEU20041.1 - 0.17 12.3 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MlrC_C PF07171.12 OEU20041.1 - 0.17 12.0 0.0 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 MlrC C-terminus Herpes_env PF01673.18 OEU20042.1 - 0.096 11.6 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Secretin_N_2 PF07655.13 OEU20042.1 - 2.4 8.8 13.2 0.11 13.1 2.1 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain TRAM_LAG1_CLN8 PF03798.16 OEU20043.1 - 0.00023 20.9 12.2 0.00028 20.7 12.2 1.0 1 0 0 1 1 1 1 TLC domain PPTA PF01239.22 OEU20044.1 - 1.3e-40 135.9 9.4 1.1e-11 44.1 0.7 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Pox_Ag35 PF03286.14 OEU20045.1 - 0.12 12.2 8.2 0.19 11.5 8.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 OEU20045.1 - 0.94 8.2 3.7 1 8.1 3.7 1.1 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 OEU20045.1 - 6.4 6.1 10.4 9.1 5.6 10.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mito_carr PF00153.27 OEU20046.1 - 3.5e-29 100.6 3.9 6.4e-13 48.4 0.2 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein RNase_PH PF01138.21 OEU20047.1 - 6.5e-23 81.7 3.6 6.5e-23 81.7 3.6 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PAF-AH_p_II PF03403.13 OEU20047.1 - 0.052 12.1 0.3 0.093 11.2 0.1 1.4 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II WW PF00397.26 OEU20048.1 - 5.1e-07 29.7 0.9 9.4e-07 28.8 0.9 1.5 1 0 0 1 1 1 1 WW domain POT1 PF02765.17 OEU20049.1 - 2.6e-13 50.0 0.0 2.6e-13 50.0 0.0 3.8 4 2 1 5 5 5 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 OEU20049.1 - 3.7e-09 36.6 0.7 6.8e-08 32.5 0.0 3.1 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein DUF1336 PF07059.12 OEU20050.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) DUF1336 PF07059.12 OEU20051.1 - 1.6e-35 123.3 0.0 1.7e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) DUF2222 PF09984.9 OEU20052.1 - 0.14 12.0 2.6 0.25 11.2 2.6 1.4 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) TPPK_C PF12555.8 OEU20052.1 - 1.6 8.8 4.3 0.81 9.8 0.7 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Aminotran_5 PF00266.19 OEU20054.1 - 1.1e-51 175.9 0.2 6.2e-44 150.5 0.1 2.3 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 OEU20054.1 - 0.00083 18.7 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 OEU20054.1 - 0.0062 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PrmA PF06325.13 OEU20056.1 - 1.8e-49 168.8 0.0 3e-47 161.5 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OEU20056.1 - 5.5e-06 26.2 0.0 9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU20056.1 - 5.7e-06 26.0 0.1 9.6e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OEU20056.1 - 0.00022 21.9 0.0 0.00053 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU20056.1 - 0.012 16.4 0.0 0.053 14.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MaoC_dehydratas PF01575.19 OEU20057.1 - 6.3e-07 29.0 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OEU20057.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase DUF3776 PF12618.8 OEU20058.1 - 1.1 9.9 10.8 0.16 12.5 0.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3776) Mpv17_PMP22 PF04117.12 OEU20060.1 - 4.4e-19 68.5 0.2 6.9e-19 67.8 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.18 OEU20061.1 - 3.2e-06 27.2 9.3 6.3e-06 26.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 OEU20062.1 - 2e-35 122.7 0.1 2.5e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OEU20062.1 - 9.3e-05 22.1 0.1 0.71 9.3 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Tmemb_cc2 PF10267.9 OEU20063.1 - 0.094 11.8 6.6 0.11 11.6 6.6 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1499 PF07386.11 OEU20064.1 - 8.7e-20 71.4 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Pro_isomerase PF00160.21 OEU20065.1 - 1e-39 136.3 0.1 1.3e-39 136.0 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAM176 PF14851.6 OEU20066.1 - 4.8 6.8 11.4 54 3.4 0.0 3.6 3 1 1 4 4 4 0 FAM176 family Copine PF07002.16 OEU20067.1 - 5.5e-49 166.6 0.0 8.1e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OEU20067.1 - 2.6e-13 50.1 0.1 1.3e-05 25.4 0.0 2.9 2 1 1 3 3 3 2 C2 domain vWA-TerF-like PF10138.9 OEU20067.1 - 2.1e-05 24.7 0.1 3.8e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus zinc_ribbon_2 PF13240.6 OEU20067.1 - 0.17 11.7 0.3 0.4 10.5 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain RRM_1 PF00076.22 OEU20068.1 - 0.0072 16.1 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 OEU20068.1 - 0.016 16.0 0.1 0.049 14.5 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OEU20068.1 - 0.038 14.4 0.2 0.095 13.2 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Jas PF16135.5 OEU20068.1 - 0.059 13.5 0.3 0.23 11.6 0.2 2.0 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf-met PF12874.7 OEU20068.1 - 0.12 12.8 0.3 0.3 11.5 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OEU20068.1 - 0.21 12.1 1.0 0.53 10.8 1.0 1.7 1 0 0 1 1 1 0 Zinc-finger double domain Menin PF05053.13 OEU20068.1 - 0.33 9.2 3.1 0.63 8.3 3.1 1.4 1 0 0 1 1 1 0 Menin YqzE PF14038.6 OEU20068.1 - 5.5 7.1 6.9 1.4 9.0 0.0 2.9 2 1 1 3 3 3 0 YqzE-like protein Glutaredoxin PF00462.24 OEU20069.1 - 6.2e-12 45.6 0.0 9.8e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF2024 PF09630.10 OEU20069.1 - 0.057 13.3 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Thiolase_N PF00108.23 OEU20070.1 - 2e-83 279.7 0.0 3.2e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OEU20070.1 - 3.1e-43 146.3 0.3 1.3e-42 144.3 0.3 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OEU20070.1 - 0.00011 21.9 1.1 0.00034 20.3 0.5 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ETF_alpha PF00766.19 OEU20071.1 - 4e-37 126.1 0.3 6.8e-37 125.4 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L32p PF01783.23 OEU20072.1 - 4.6e-08 33.2 1.1 7.6e-08 32.5 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family DFF40 PF09230.10 OEU20072.1 - 0.026 14.2 1.0 0.035 13.7 1.0 1.1 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Androgen_recep PF02166.16 OEU20072.1 - 0.16 10.8 0.1 0.17 10.7 0.1 1.0 1 0 0 1 1 1 0 Androgen receptor PsbQ PF05757.11 OEU20073.1 - 0.016 14.9 9.1 0.11 12.2 9.1 2.0 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF4327 PF14217.6 OEU20073.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Xan_ur_permease PF00860.20 OEU20075.1 - 1.5e-52 178.6 27.3 1.1e-51 175.7 23.1 2.4 2 1 0 2 2 2 2 Permease family ATP-synt_S1 PF05827.12 OEU20076.1 - 0.004 17.0 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) BING4CT PF08149.11 OEU20076.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain TarH PF02203.15 OEU20078.1 - 0.0089 16.0 1.9 0.011 15.6 1.9 1.1 1 0 0 1 1 1 1 Tar ligand binding domain homologue DUF4698 PF15769.5 OEU20078.1 - 0.15 11.1 0.4 0.2 10.7 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) MSP PF01716.18 OEU20079.1 - 1.9e-90 302.3 0.4 2.5e-90 301.9 0.4 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Ras PF00071.22 OEU20080.1 - 3.9e-15 55.8 0.0 3.6e-07 29.9 0.0 3.7 4 0 0 4 4 4 2 Ras family EF_assoc_2 PF08356.12 OEU20080.1 - 1.5e-11 44.1 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 OEU20080.1 - 2.4e-11 43.9 0.3 0.0083 16.3 0.0 3.9 3 1 1 4 4 4 3 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 OEU20080.1 - 1.1e-08 35.4 4.1 3.8e-07 30.5 4.1 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU20080.1 - 1.6e-08 33.5 5.8 0.0011 18.3 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 OEU20080.1 - 5.9e-08 31.9 2.7 0.0082 15.6 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU20080.1 - 3.6e-07 29.6 8.5 0.0069 16.2 0.1 3.4 3 0 0 3 3 2 2 EF-hand domain MMR_HSR1 PF01926.23 OEU20080.1 - 5.3e-07 29.7 0.0 0.0015 18.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OEU20080.1 - 1.5e-06 28.7 0.2 0.13 12.6 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain Arf PF00025.21 OEU20080.1 - 3.5e-06 26.6 0.0 0.077 12.5 0.0 3.2 3 0 0 3 3 3 1 ADP-ribosylation factor family Septin PF00735.18 OEU20080.1 - 1.5e-05 24.4 0.1 0.084 12.1 0.0 2.2 2 0 0 2 2 2 2 Septin Dynamin_N PF00350.23 OEU20080.1 - 7.1e-05 22.9 0.2 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 OEU20080.1 - 0.00018 21.5 0.1 0.35 10.7 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 OEU20080.1 - 0.00052 20.3 0.2 0.015 15.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OEU20080.1 - 0.00064 20.3 0.3 0.56 10.7 0.1 2.7 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 OEU20080.1 - 0.0009 19.7 0.0 2.5 8.5 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OEU20080.1 - 0.002 17.5 0.0 0.66 9.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 OEU20080.1 - 0.0023 17.5 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 OEU20080.1 - 0.003 17.3 0.4 0.5 10.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 OEU20080.1 - 0.004 16.9 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 OEU20080.1 - 0.0047 16.1 0.0 0.86 8.7 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 OEU20080.1 - 0.0066 16.7 0.0 5.9 7.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 OEU20080.1 - 0.0081 15.4 0.2 0.43 9.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 OEU20080.1 - 0.011 15.2 0.4 0.081 12.4 0.1 2.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OEU20080.1 - 0.014 15.0 0.1 1.4 8.4 0.0 3.2 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.6 OEU20080.1 - 0.018 14.9 3.0 0.23 11.3 0.5 3.0 3 0 0 3 3 2 0 EF-hand domain pair NACHT PF05729.12 OEU20080.1 - 0.022 14.7 0.0 4.7 7.1 0.0 2.8 3 0 0 3 3 3 0 NACHT domain FeoB_N PF02421.18 OEU20080.1 - 0.027 14.0 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B FUSC PF04632.12 OEU20080.1 - 0.047 12.2 0.0 0.072 11.6 0.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PduV-EutP PF10662.9 OEU20080.1 - 0.049 13.4 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 OEU20080.1 - 0.049 13.5 0.0 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OEU20080.1 - 0.11 12.9 0.0 17 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Cyclin_N PF00134.23 OEU20081.1 - 0.013 15.3 0.5 0.049 13.4 0.1 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU20081.1 - 0.026 14.6 1.2 0.16 12.1 1.2 2.4 1 1 0 1 1 1 0 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 OEU20081.1 - 0.068 13.6 0.7 0.26 11.7 0.6 2.0 1 1 1 2 2 2 0 Cyclin C-terminal domain Ndc1_Nup PF09531.10 OEU20081.1 - 1.1 7.8 7.6 1.1 7.9 6.8 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 OEU20082.1 - 7.2e-11 42.5 0.0 0.08 13.5 0.0 4.1 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU20082.1 - 1.5e-06 28.7 0.0 0.073 13.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU20082.1 - 3.2e-06 27.3 4.0 0.43 11.0 0.0 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU20082.1 - 2.8e-05 24.2 1.0 8.6 7.3 0.0 6.3 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 OEU20082.1 - 0.0013 19.1 6.9 30 5.3 0.0 6.6 8 0 0 8 8 8 1 Ankyrin repeat TMEM171 PF15471.6 OEU20082.1 - 5.3 5.9 11.2 0.3 10.1 3.5 2.6 2 0 0 2 2 2 0 Transmembrane protein family 171 TMEM220 PF15071.6 OEU20083.1 - 6.1e-07 30.1 0.6 1e-06 29.4 0.6 1.4 1 0 0 1 1 1 1 Transmembrane family 220, helix DUF4191 PF13829.6 OEU20083.1 - 0.24 10.7 0.1 0.3 10.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) CN_hydrolase PF00795.22 OEU20084.1 - 7.6e-42 143.5 0.0 9.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LRRC37AB_C PF14914.6 OEU20086.1 - 0.98 9.3 3.3 0.37 10.7 0.1 1.9 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain RFXA_RFXANK_bdg PF15289.6 OEU20086.1 - 4.5 7.6 6.1 18 5.7 0.1 2.3 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DUF4336 PF14234.6 OEU20088.1 - 1.8e-100 336.2 0.0 2.1e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) PDR_CDR PF06422.12 OEU20090.1 - 0.52 10.2 4.1 0.45 10.4 0.7 2.7 2 0 0 2 2 2 0 CDR ABC transporter SAC3_GANP PF03399.16 OEU20091.1 - 5.7e-17 62.0 0.9 1.1e-16 61.1 0.9 1.4 1 1 0 1 1 1 1 SAC3/GANP family zf-CCCH_4 PF18044.1 OEU20091.1 - 1.4e-06 27.9 4.4 2.7e-06 27.0 4.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OEU20091.1 - 2.1e-06 27.6 6.1 4.9e-06 26.4 6.1 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OEU20091.1 - 1.9e-05 24.4 7.1 2.3e-05 24.2 5.1 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OEU20091.1 - 0.00034 21.3 1.5 0.001 19.7 1.3 1.9 1 1 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 OEU20091.1 - 0.0024 18.3 6.7 0.0051 17.2 3.8 2.6 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OEU20091.1 - 0.023 14.9 1.3 0.066 13.4 1.3 1.9 1 0 0 1 1 1 0 Zinc-finger containing family MatE PF01554.18 OEU20092.1 - 3.3e-07 30.1 16.1 3.5e-05 23.5 2.6 3.6 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 OEU20092.1 - 6.7e-06 26.2 10.3 6.7e-06 26.2 10.3 3.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Rhodanese PF00581.20 OEU20093.1 - 5.1e-05 23.7 0.0 6.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain BLM_N PF16202.5 OEU20093.1 - 0.25 10.4 0.1 0.24 10.5 0.1 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein DUF1510 PF07423.11 OEU20094.1 - 0.056 13.6 3.8 0.15 12.2 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) SNURF PF07192.11 OEU20094.1 - 0.068 13.0 1.7 0.29 11.0 0.6 2.1 2 0 0 2 2 2 0 SNURF/RPN4 protein SHE3 PF17078.5 OEU20095.1 - 0.0019 18.0 0.1 0.0022 17.7 0.1 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Thioredoxin PF00085.20 OEU20096.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin SR-25 PF10500.9 OEU20096.1 - 2.3 7.8 7.6 4 7.0 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRAPP PF04051.16 OEU20097.1 - 6e-29 100.7 0.0 6.9e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CwfJ_C_1 PF04677.15 OEU20098.1 - 8.9e-10 38.5 0.2 2.2e-09 37.2 0.1 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OEU20098.1 - 1.2e-09 38.9 0.2 2.2e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 RVT_1 PF00078.27 OEU20100.1 - 1.9e-07 30.9 0.0 5.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU20100.1 - 0.02 15.6 0.8 0.076 13.7 0.8 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase LBR_tudor PF09465.10 OEU20100.1 - 0.11 12.3 0.2 0.35 10.7 0.2 1.8 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain SSP160 PF06933.11 OEU20100.1 - 0.32 9.2 11.7 0.66 8.1 11.7 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SNF2_N PF00176.23 OEU20101.1 - 4.6e-42 144.0 0.1 9.6e-42 142.9 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU20101.1 - 1.1e-11 45.1 0.0 4e-11 43.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU20101.1 - 4.5e-09 36.3 0.0 1.4e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CW PF07496.15 OEU20101.1 - 7.3e-06 25.9 8.5 7.3e-06 25.9 8.5 3.2 3 0 0 3 3 3 1 CW-type Zinc Finger ERCC3_RAD25_C PF16203.5 OEU20101.1 - 0.018 14.3 0.0 0.018 14.3 0.0 2.9 5 0 0 5 5 5 0 ERCC3/RAD25/XPB C-terminal helicase ADD_ATRX PF17981.1 OEU20101.1 - 3.6 7.5 11.8 6.1 6.8 2.8 2.8 2 0 0 2 2 2 0 Cysteine Rich ADD domain TRAPPC-Trs85 PF12739.7 OEU20102.1 - 1.3e-55 189.0 1.0 1.6e-54 185.4 1.0 2.2 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 OEU20102.1 - 0.016 14.7 0.2 0.66 9.3 0.1 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP DUF4138 PF13595.6 OEU20102.1 - 0.3 10.3 0.9 0.54 9.5 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Fez1 PF06818.15 OEU20103.1 - 0.073 13.5 0.2 0.073 13.5 0.2 2.4 2 0 0 2 2 2 0 Fez1 Tropomodulin PF03250.14 OEU20103.1 - 0.51 10.4 5.8 0.16 12.1 0.5 2.4 2 0 0 2 2 2 0 Tropomodulin Kelch_4 PF13418.6 OEU20104.1 - 4e-22 78.0 7.6 1.5e-06 28.1 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OEU20104.1 - 1.5e-20 72.5 5.4 6e-06 25.7 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OEU20104.1 - 9.2e-20 70.2 4.2 9.5e-08 32.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OEU20104.1 - 9e-16 57.5 3.8 7.4e-05 22.6 0.0 7.1 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 OEU20104.1 - 3e-12 46.5 13.1 0.0068 16.7 0.1 6.3 5 2 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OEU20104.1 - 9.3e-11 41.3 0.4 0.00079 19.3 0.0 5.2 5 0 0 5 5 5 3 Kelch motif NPR2 PF06218.11 OEU20104.1 - 0.014 14.2 1.0 0.02 13.6 1.0 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 ABC2_membrane_3 PF12698.7 OEU20104.1 - 0.014 14.5 0.0 0.11 11.5 0.0 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3439 PF11921.8 OEU20104.1 - 0.86 9.6 7.2 2.2 8.3 7.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Qn_am_d_aIII PF09099.10 OEU20105.1 - 0.0045 17.3 3.3 0.58 10.6 0.1 3.3 2 2 1 3 3 3 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF1827 PF08860.10 OEU20105.1 - 0.13 12.6 0.9 0.64 10.3 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1827) DUF1654 PF07867.11 OEU20105.1 - 0.25 11.1 2.5 7 6.5 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1654) SBD_N PF07005.11 OEU20106.1 - 9.7e-45 153.1 0.0 2.4e-44 151.8 0.0 1.6 1 1 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 OEU20106.1 - 3.5e-35 122.0 0.0 9.8e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Tox-PL-2 PF15643.6 OEU20106.1 - 0.033 14.3 0.0 6.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Papain fold toxin 2 Phlebovirus_NSM PF07246.11 OEU20106.1 - 0.12 11.7 0.4 0.25 10.7 0.4 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AIRC PF00731.20 OEU20107.1 - 0.013 15.1 1.2 0.016 14.8 1.2 1.1 1 0 0 1 1 1 0 AIR carboxylase DUF3824 PF12868.7 OEU20107.1 - 0.064 13.9 4.0 0.085 13.5 4.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ABC2_membrane PF01061.24 OEU20108.1 - 1e-25 90.4 19.3 1e-25 90.4 19.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OEU20108.1 - 9.1e-15 55.4 0.0 1.7e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 OEU20108.1 - 0.00013 22.6 0.0 0.00021 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OEU20108.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU20108.1 - 0.0023 17.9 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OEU20108.1 - 0.0099 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OEU20108.1 - 0.021 15.0 0.0 0.091 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU20108.1 - 0.026 14.9 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OEU20108.1 - 0.095 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OEU20108.1 - 0.1 12.4 0.3 0.61 9.8 0.1 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 OEU20108.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OEU20108.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 OEU20108.1 - 0.19 12.3 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Peptidase_C15 PF01470.17 OEU20109.1 - 2e-12 47.7 0.0 3.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Pyroglutamyl peptidase Pho88 PF10032.9 OEU20109.1 - 0.14 11.5 2.7 7.4 5.8 0.1 2.1 2 0 0 2 2 2 0 Phosphate transport (Pho88) Iwr1 PF08574.10 OEU20109.1 - 0.16 13.0 5.0 0.7 10.9 1.8 2.2 2 0 0 2 2 2 0 Transcription factor Iwr1 STAC2_u1 PF16664.5 OEU20109.1 - 0.19 12.2 3.2 0.32 11.5 0.8 2.0 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Rsc14 PF08586.10 OEU20109.1 - 0.91 10.4 4.9 1.5 9.7 0.1 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit PDZ_6 PF17820.1 OEU20113.1 - 9.2e-09 35.0 0.1 1.6e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU20113.1 - 4.2e-08 33.4 0.3 7e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU20113.1 - 4.6e-05 23.7 0.0 7.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Synaptobrevin PF00957.21 OEU20114.1 - 0.1 12.4 0.4 0.1 12.4 0.4 2.1 2 0 0 2 2 2 0 Synaptobrevin Connexin PF00029.19 OEU20114.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.5 2 1 0 2 2 2 0 Connexin DUF2547 PF10818.8 OEU20114.1 - 3.6 8.6 0.0 3.6 8.6 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2547) Neugrin PF06413.11 OEU20114.1 - 4.4 7.3 9.6 1.1 9.2 2.5 2.3 2 0 0 2 2 2 0 Neugrin zf-RING_2 PF13639.6 OEU20116.1 - 0.025 14.9 3.7 0.12 12.7 3.9 1.9 1 1 0 1 1 1 0 Ring finger domain PapD_C PF02753.17 OEU20116.1 - 0.069 13.5 0.3 0.43 11.0 0.3 2.1 1 1 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain zf-C3HC4_4 PF15227.6 OEU20116.1 - 0.1 12.8 0.1 0.1 12.8 0.1 2.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING UTP15_C PF09384.10 OEU20118.1 - 1.6e-42 144.7 0.0 2.5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OEU20118.1 - 1.4e-16 60.6 7.2 5.1e-05 24.0 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20118.1 - 2.5e-07 30.9 0.2 0.00016 21.9 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OEU20118.1 - 0.047 13.0 0.0 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Wbp11 PF09429.10 OEU20118.1 - 0.21 12.0 0.2 0.21 12.0 0.2 1.8 2 0 0 2 2 2 0 WW domain binding protein 11 PP1 PF07430.11 OEU20119.1 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain 2OG-FeII_Oxy_2 PF13532.6 OEU20120.1 - 4.4e-08 33.6 0.0 4.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5316 PF17247.2 OEU20121.1 - 0.025 14.6 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) HSF_DNA-bind PF00447.17 OEU20123.1 - 1.4e-19 70.5 0.2 1.6e-19 70.3 0.2 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Cas_St_Csn2 PF16813.5 OEU20123.1 - 0.12 11.4 0.5 0.14 11.2 0.5 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St ARD PF03079.14 OEU20124.1 - 1.9e-36 125.6 0.7 9.6e-36 123.3 0.7 1.9 1 1 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OEU20124.1 - 1.5e-07 31.0 0.1 2.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OEU20124.1 - 2.1e-05 24.5 1.2 3.1e-05 23.9 1.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OEU20124.1 - 0.00028 20.5 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Cupin cobW PF02492.19 OEU20126.1 - 2.5e-52 177.0 0.8 3.5e-52 176.6 0.8 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OEU20126.1 - 1.8e-14 53.4 0.0 3.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 OEU20126.1 - 0.00079 19.0 0.6 0.016 14.8 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU20126.1 - 0.003 17.5 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OEU20126.1 - 0.0087 16.5 0.0 0.025 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 OEU20126.1 - 0.024 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 OEU20126.1 - 0.054 13.5 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OEU20126.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 OEU20126.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 OEU20126.1 - 0.16 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OEU20126.1 - 0.18 12.0 0.7 0.43 10.8 0.0 1.9 3 0 0 3 3 3 0 AAA domain DUF1670 PF07900.11 OEU20127.1 - 0.063 12.6 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) Peptidase_S8 PF00082.22 OEU20129.1 - 6.1e-48 163.6 2.1 1.2e-47 162.6 2.1 1.5 1 0 0 1 1 1 1 Subtilase family SpoIIP PF07454.11 OEU20129.1 - 0.025 14.1 1.7 0.041 13.3 1.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EamA PF00892.20 OEU20130.1 - 1.2e-21 77.3 23.8 5.3e-11 42.8 8.8 3.1 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU20130.1 - 0.0083 15.5 1.3 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.14 OEU20130.1 - 0.76 8.8 5.7 3.4 6.7 1.7 2.2 2 0 0 2 2 2 0 Magnesium transporter NIPA DUF2514 PF10721.9 OEU20131.1 - 0.031 14.3 0.3 0.046 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Ly49 PF08391.10 OEU20131.1 - 0.12 12.8 0.3 0.19 12.1 0.3 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region adh_short PF00106.25 OEU20134.1 - 1.1e-24 87.0 1.3 1.9e-24 86.2 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU20134.1 - 2.2e-15 56.9 0.1 3e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU20134.1 - 4.8e-05 23.3 1.3 0.00028 20.8 0.2 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OEU20134.1 - 0.031 13.7 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SUIM_assoc PF16619.5 OEU20136.1 - 7.1 6.8 24.4 3.8 7.6 1.5 4.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF5327 PF17261.2 OEU20136.1 - 9.2 7.1 20.6 0.28 12.0 0.9 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5327) TrkH PF02386.16 OEU20137.1 - 0.054 11.9 0.1 0.091 11.2 0.1 1.3 1 0 0 1 1 1 0 Cation transport protein ABC_tran PF00005.27 OEU20138.1 - 1.3e-18 67.9 0.0 3.3e-18 66.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU20138.1 - 3.9e-12 46.6 0.3 6e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OEU20138.1 - 0.00011 21.9 0.1 0.00022 20.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 OEU20138.1 - 0.00048 19.6 0.5 0.024 14.1 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 OEU20138.1 - 0.002 17.5 0.7 0.0085 15.5 0.1 2.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family NACHT PF05729.12 OEU20138.1 - 0.0083 16.1 1.7 0.1 12.5 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OEU20138.1 - 0.0088 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU20138.1 - 0.015 15.6 0.5 0.075 13.3 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OEU20138.1 - 0.022 15.3 3.2 0.088 13.3 0.3 2.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 OEU20138.1 - 0.024 14.4 1.1 0.04 13.6 0.3 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 OEU20138.1 - 0.035 13.7 0.0 0.084 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OEU20138.1 - 0.037 14.3 0.1 0.037 14.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OEU20138.1 - 0.038 13.9 0.7 0.065 13.1 0.2 1.6 2 0 0 2 2 1 0 RsgA GTPase AAA_30 PF13604.6 OEU20138.1 - 0.041 13.6 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU20138.1 - 0.065 13.4 0.1 0.14 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 OEU20138.1 - 0.1 13.0 0.1 0.85 10.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Imm5 PF14423.6 OEU20138.1 - 0.11 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 G-alpha PF00503.20 OEU20138.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.21 OEU20138.1 - 0.11 12.0 0.2 0.23 10.9 0.2 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family SRP54 PF00448.22 OEU20138.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OEU20138.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU20138.1 - 0.14 12.7 0.2 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OEU20138.1 - 0.14 12.2 0.1 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 OEU20138.1 - 0.15 11.8 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RWD PF05773.22 OEU20139.1 - 4.2e-06 27.0 0.0 8.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RWD domain COesterase PF00135.28 OEU20140.1 - 1.7e-21 76.7 0.0 2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF1687 PF07955.11 OEU20140.1 - 0.018 15.5 0.0 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) Abhydrolase_3 PF07859.13 OEU20140.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box PF00646.33 OEU20142.1 - 0.0032 17.3 1.5 0.017 15.0 0.1 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OEU20142.1 - 0.0046 16.8 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OEU20142.1 - 0.04 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box ChaB PF06150.12 OEU20142.1 - 0.13 12.9 0.5 3.9 8.1 0.2 2.6 2 0 0 2 2 2 0 ChaB ABC1 PF03109.16 OEU20143.1 - 1e-23 83.7 0.3 2.9e-23 82.3 0.1 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 OEU20143.1 - 1.9e-05 24.7 0.1 4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU20143.1 - 4.6e-05 23.1 0.0 0.00078 19.1 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 OEU20143.1 - 0.00036 20.0 0.2 0.0056 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20143.1 - 0.002 17.4 0.1 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase WaaY PF06176.11 OEU20143.1 - 0.029 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FA_synthesis PF02504.15 OEU20143.1 - 0.042 12.9 0.1 0.087 11.9 0.1 1.4 1 0 0 1 1 1 0 Fatty acid synthesis protein Arm_2 PF04826.13 OEU20143.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like DUF2407_C PF13373.6 OEU20144.1 - 3.6e-17 62.9 0.3 3.6e-17 62.9 0.3 2.9 3 1 0 3 3 3 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OEU20144.1 - 2.1e-10 41.1 0.9 5.6e-10 39.7 0.9 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU20144.1 - 0.00035 20.6 0.2 0.00085 19.4 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OEU20144.1 - 0.0084 15.8 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Baculo_PP31 PF05311.11 OEU20144.1 - 0.026 14.0 0.4 0.059 12.9 0.4 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 OEU20144.1 - 0.038 13.6 9.3 0.025 14.2 1.4 2.3 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.13 OEU20144.1 - 1.4 9.6 5.8 1.1 10.0 1.2 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 OEU20144.1 - 1.8 7.2 4.8 3.2 6.4 4.8 1.5 1 0 0 1 1 1 0 Presenilin FAST_1 PF06743.15 OEU20145.1 - 1.3e-12 47.4 0.4 0.036 14.0 0.0 7.7 8 1 1 9 9 9 4 FAST kinase-like protein, subdomain 1 RAP PF08373.10 OEU20145.1 - 1.7e-08 34.5 0.4 3.9e-08 33.3 0.4 1.6 1 0 0 1 1 1 1 RAP domain FANCI_HD1 PF14679.6 OEU20145.1 - 0.063 13.2 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 FANCI helical domain 1 DUF1601 PF07671.11 OEU20145.1 - 1.5 8.7 9.9 40 4.2 0.0 6.0 7 0 0 7 7 7 0 Protein of unknown function (DUF1601) Lum_binding PF00677.17 OEU20146.1 - 8.6e-42 141.0 2.7 9.1e-21 73.7 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain MFS_1 PF07690.16 OEU20147.1 - 7.9e-39 133.6 23.9 7.9e-39 133.6 23.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU20147.1 - 3e-36 125.3 23.7 3.7e-31 108.5 3.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter Halogen_Hydrol PF10112.9 OEU20147.1 - 6 6.8 6.7 0.22 11.5 0.4 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Det1 PF09737.9 OEU20148.1 - 0.0088 15.2 1.3 0.015 14.4 1.3 1.3 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 DUF4823 PF16105.5 OEU20148.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) ShK PF01549.24 OEU20149.1 - 0.065 13.8 2.7 0.065 13.8 2.7 2.3 3 1 0 3 3 3 0 ShK domain-like fn3_PAP PF17808.1 OEU20149.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase PTN_MK_N PF05196.13 OEU20149.1 - 8.1 6.8 9.3 0.32 11.2 3.2 1.8 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain Ank_4 PF13637.6 OEU20151.1 - 8.4e-07 29.4 0.3 4.8e-05 23.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU20151.1 - 2e-06 28.3 0.0 3.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU20151.1 - 0.0013 19.0 0.1 0.15 12.4 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU20151.1 - 0.0042 17.5 0.1 2.2 9.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Methyltransf_24 PF13578.6 OEU20152.1 - 3.6e-07 31.2 0.0 9.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 OEU20152.1 - 4e-07 29.4 0.4 2.1e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase MIR PF02815.19 OEU20152.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 MIR domain Inhibitor_I9 PF05922.16 OEU20153.1 - 0.21 12.3 1.3 1.2 9.8 1.3 2.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 Tankyrase_bdg_C PF15327.6 OEU20153.1 - 2.1 8.8 9.3 0.06 13.8 0.7 2.7 3 0 0 3 3 3 0 Tankyrase binding protein C terminal domain Peptidase_M1 PF01433.20 OEU20154.1 - 7.7e-85 283.9 1.1 5.1e-84 281.2 0.5 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 OEU20154.1 - 5.3e-68 229.9 0.0 1.9e-66 224.8 0.0 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OEU20154.1 - 1.9e-50 171.7 1.8 3.7e-50 170.7 1.8 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain VitK2_biosynth PF02621.14 OEU20154.1 - 0.038 13.5 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Menaquinone biosynthesis PIG-Y PF15159.6 OEU20155.1 - 0.0069 17.3 1.1 0.012 16.5 1.1 1.5 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF202 PF02656.15 OEU20155.1 - 0.42 11.1 3.1 1.9 9.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) TMA7 PF09072.10 OEU20156.1 - 2.4 9.1 14.5 15 6.5 0.2 3.2 3 0 0 3 3 3 0 Translation machinery associated TMA7 ETRAMP PF09716.10 OEU20156.1 - 4 7.6 12.6 1.8 8.7 8.5 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NOA36 PF06524.12 OEU20156.1 - 9.9 5.4 7.1 0.63 9.3 1.7 1.6 2 0 0 2 2 2 0 NOA36 protein DUF2107 PF09880.9 OEU20157.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) LRR_8 PF13855.6 OEU20158.1 - 1.5e-09 37.4 3.6 4.2e-05 23.2 0.1 3.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OEU20158.1 - 0.0027 18.1 20.4 0.099 13.1 1.1 5.5 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) ETRAMP PF09716.10 OEU20158.1 - 0.066 13.3 9.1 2.2 8.4 6.8 3.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) LRR_1 PF00560.33 OEU20158.1 - 0.1 13.2 9.5 12 6.9 0.1 6.1 4 1 1 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 OEU20158.1 - 0.18 11.3 3.9 0.18 11.3 0.4 2.7 2 1 0 2 2 2 0 Leucine-rich repeat bZIP_1 PF00170.21 OEU20159.1 - 0.00023 21.2 1.1 0.00032 20.7 1.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor Tektin PF03148.14 OEU20159.1 - 0.00058 18.7 0.3 0.00075 18.4 0.3 1.1 1 0 0 1 1 1 1 Tektin family Lectin_N PF03954.14 OEU20159.1 - 0.00063 19.5 0.1 0.00088 19.0 0.1 1.2 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain SseC PF04888.12 OEU20159.1 - 0.0018 17.9 0.2 0.0024 17.5 0.2 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ZapB PF06005.12 OEU20159.1 - 0.0026 18.2 0.5 0.004 17.6 0.5 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 OEU20159.1 - 0.0034 17.1 1.5 0.0057 16.4 1.5 1.2 1 0 0 1 1 1 1 Septum formation initiator APG6_N PF17675.1 OEU20159.1 - 0.0044 17.6 0.2 0.0063 17.0 0.2 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 OEU20159.1 - 0.0046 17.0 1.0 0.0074 16.3 1.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 OEU20159.1 - 0.0052 17.1 0.2 0.0091 16.3 0.2 1.4 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GrpE PF01025.19 OEU20159.1 - 0.01 15.5 0.3 0.014 15.0 0.3 1.2 1 0 0 1 1 1 0 GrpE DUF5082 PF16888.5 OEU20159.1 - 0.017 15.4 0.7 0.028 14.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SlyX PF04102.12 OEU20159.1 - 0.021 15.4 0.0 0.035 14.7 0.0 1.3 1 0 0 1 1 1 0 SlyX TelA PF05816.11 OEU20159.1 - 0.021 13.9 0.2 0.03 13.4 0.2 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) CENP-F_leu_zip PF10473.9 OEU20159.1 - 0.023 14.7 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 OEU20159.1 - 0.026 14.4 0.9 0.046 13.6 0.9 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMCO5 PF14992.6 OEU20159.1 - 0.038 13.5 0.1 0.049 13.2 0.1 1.1 1 0 0 1 1 1 0 TMCO5 family HOOK PF05622.12 OEU20159.1 - 0.046 11.9 0.2 0.059 11.5 0.2 1.0 1 0 0 1 1 1 0 HOOK protein Snapin_Pallidin PF14712.6 OEU20159.1 - 0.046 14.1 0.3 0.068 13.6 0.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin LRRFIP PF09738.9 OEU20159.1 - 0.051 13.1 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 LRRFIP family DUF1664 PF07889.12 OEU20159.1 - 0.052 13.6 0.2 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NRBF2 PF08961.10 OEU20159.1 - 0.053 13.1 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TMF_DNA_bd PF12329.8 OEU20159.1 - 0.06 13.4 0.4 0.089 12.8 0.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 OEU20159.1 - 0.061 12.2 0.4 0.079 11.8 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4094 PF13334.6 OEU20159.1 - 0.069 13.6 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Prefoldin_2 PF01920.20 OEU20159.1 - 0.069 13.1 0.4 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Prefoldin subunit YabA PF06156.13 OEU20159.1 - 0.069 13.8 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA THOC7 PF05615.13 OEU20159.1 - 0.073 13.4 0.5 0.12 12.7 0.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 GAS PF13851.6 OEU20159.1 - 0.077 12.3 0.3 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 OEU20159.1 - 0.084 13.2 0.4 0.17 12.2 0.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family CobN-Mg_chel PF02514.16 OEU20159.1 - 0.088 10.5 0.1 0.1 10.4 0.1 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Prominin PF05478.11 OEU20159.1 - 0.1 10.6 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Prominin JIP_LZII PF16471.5 OEU20159.1 - 0.1 12.8 0.6 0.15 12.2 0.6 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II LPP PF04728.13 OEU20159.1 - 0.11 13.0 1.7 0.4 11.1 1.7 2.0 1 1 0 1 1 1 0 Lipoprotein leucine-zipper ADIP PF11559.8 OEU20159.1 - 0.12 12.5 0.7 0.17 12.0 0.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cnn_1N PF07989.11 OEU20159.1 - 0.14 12.4 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 XhlA PF10779.9 OEU20159.1 - 0.17 12.1 0.3 0.28 11.4 0.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA HALZ PF02183.18 OEU20159.1 - 0.18 12.1 0.5 0.32 11.3 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 OEU20159.1 - 0.29 11.2 1.1 0.56 10.3 1.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper 2OG-FeII_Oxy_3 PF13640.6 OEU20161.1 - 1.4e-07 32.3 0.1 2.1e-06 28.5 0.1 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cob_adeno_trans PF01923.18 OEU20162.1 - 1.5e-40 139.0 0.0 1.1e-39 136.2 0.0 1.9 1 1 0 1 1 1 1 Cobalamin adenosyltransferase WGG PF10273.9 OEU20162.1 - 0.072 13.8 0.6 0.59 10.8 0.1 2.5 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 Androgen_recep PF02166.16 OEU20162.1 - 3.2 6.5 6.7 4.3 6.1 6.7 1.1 1 0 0 1 1 1 0 Androgen receptor BCIP PF13862.6 OEU20163.1 - 3e-31 108.8 0.8 3e-31 108.8 0.8 2.9 1 1 1 2 2 1 1 p21-C-terminal region-binding protein YL1 PF05764.13 OEU20163.1 - 0.00021 21.5 17.7 0.00039 20.6 17.7 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Tim54 PF11711.8 OEU20163.1 - 0.044 12.6 8.6 0.099 11.4 8.6 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mpp10 PF04006.12 OEU20163.1 - 0.049 12.1 24.1 0.093 11.2 24.1 1.4 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 OEU20163.1 - 0.061 11.5 24.9 0.09 11.0 24.9 1.2 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 OEU20163.1 - 0.07 12.0 8.4 0.092 11.6 8.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 OEU20163.1 - 0.14 11.4 3.6 0.25 10.5 3.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter OATP PF03137.20 OEU20163.1 - 0.59 8.4 6.3 0.11 10.7 1.9 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 OEU20163.1 - 2 7.1 11.4 3.6 6.2 11.4 1.4 1 0 0 1 1 1 0 Presenilin MRP-S25 PF13741.6 OEU20163.1 - 2.1 7.8 9.2 4 6.9 9.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 Lin-8 PF03353.15 OEU20163.1 - 2.4 7.7 15.0 0.23 11.0 10.7 1.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 OEU20163.1 - 3.1 7.1 33.0 5.4 6.3 33.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OEU20163.1 - 5.1 6.3 33.1 8.1 5.7 33.1 1.2 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 OEU20163.1 - 7.1 3.6 12.8 0.32 8.1 7.3 1.5 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer CCSAP PF15748.5 OEU20163.1 - 7.1 6.7 19.4 14 5.8 19.4 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 OEU20163.1 - 8.6 6.3 6.8 13 5.7 5.3 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.7 OEU20164.1 - 1.3e-22 80.1 0.0 4e-13 49.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU20164.1 - 2.8e-20 72.4 0.5 1.7e-08 34.8 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU20164.1 - 1.2e-15 57.4 0.1 9.2e-05 22.7 0.1 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OEU20164.1 - 2.8e-15 56.0 0.0 0.00019 21.8 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OEU20164.1 - 6.9e-13 47.5 0.5 1.7e-05 24.8 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeat DnaJ PF00226.31 OEU20164.1 - 0.00082 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TRAP-delta PF05404.12 OEU20164.1 - 0.0098 15.4 0.9 0.019 14.5 0.9 1.4 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) PglD_N PF17836.1 OEU20164.1 - 0.027 15.1 0.0 0.18 12.5 0.0 2.3 1 1 1 2 2 2 0 PglD N-terminal domain SCIMP PF15050.6 OEU20165.1 - 0.034 14.6 0.7 0.034 14.6 0.7 3.9 2 1 2 4 4 4 0 SCIMP protein PT PF04886.12 OEU20165.1 - 2 8.1 54.2 6.3e+03 -3.2 4.6 5.4 2 1 0 2 2 2 0 PT repeat DUF285 PF03382.14 OEU20166.1 - 1.1e-180 590.1 103.5 1.5e-35 121.5 11.8 5.1 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 DUF4695 PF15766.5 OEU20166.1 - 0.00022 21.4 0.1 0.24 11.6 0.0 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4695) Phage_tail_2 PF06199.11 OEU20166.1 - 0.00037 20.6 2.3 1.3 9.1 0.0 3.7 2 1 1 3 3 3 2 Phage tail tube protein BssS PF13991.6 OEU20166.1 - 0.00052 20.0 8.9 22 5.2 0.1 8.9 11 2 1 12 12 12 0 BssS protein family Chordopox_E11 PF06138.12 OEU20166.1 - 0.014 15.7 7.1 46 4.3 0.1 5.6 1 1 5 7 7 7 0 Chordopoxvirus E11 protein F_bP_aldolase PF01116.20 OEU20166.1 - 0.07 12.6 0.0 35 3.8 0.0 3.5 3 1 0 4 4 4 0 Fructose-bisphosphate aldolase class-II CdhD PF03599.16 OEU20166.1 - 0.55 8.9 3.9 6.7 5.3 0.2 3.5 3 2 0 3 3 3 0 CO dehydrogenase/acetyl-CoA synthase delta subunit CPSase_L_D3 PF02787.19 OEU20166.1 - 0.82 10.0 7.3 94 3.4 0.1 4.9 1 1 4 6 6 6 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Prok_Ub PF14454.6 OEU20166.1 - 4.8 6.9 14.4 7.5 6.3 0.1 6.4 5 2 6 11 11 11 0 Prokaryotic Ubiquitin RNase_T PF00929.24 OEU20168.1 - 5e-08 33.7 0.0 6.9e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Exonuclease DUF3368 PF11848.8 OEU20168.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) GAGBD PF16828.5 OEU20169.1 - 0.015 15.4 0.2 0.033 14.3 0.2 1.5 1 0 0 1 1 1 0 GAG-binding domain on surface antigen YkyA PF10368.9 OEU20172.1 - 0.61 9.7 3.0 0.33 10.6 0.9 1.6 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein SNF2_N PF00176.23 OEU20173.1 - 2.9e-65 220.3 0.3 2.9e-65 220.3 0.3 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU20173.1 - 3.1e-20 72.6 0.1 5.8e-19 68.5 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 OEU20173.1 - 2.7e-13 50.0 15.3 4.3e-12 46.2 7.2 2.7 1 1 1 2 2 2 2 HSA DEAD PF00270.29 OEU20173.1 - 0.00024 20.9 0.9 0.0015 18.3 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_14 PF13173.6 OEU20173.1 - 0.031 14.3 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain CHASE3 PF05227.13 OEU20173.1 - 0.29 11.0 6.8 2.6 8.0 3.6 2.6 2 0 0 2 2 2 0 CHASE3 domain UvrD_C PF13361.6 OEU20173.1 - 0.89 8.9 8.6 1.9 7.8 8.6 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Beta_helix PF13229.6 OEU20174.1 - 1.8e-06 27.9 3.6 2.4e-06 27.5 3.6 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 OEU20174.1 - 0.00037 19.8 0.3 0.0011 18.3 0.3 1.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Utp14 PF04615.13 OEU20175.1 - 0.22 10.0 33.9 0.32 9.5 33.9 1.1 1 0 0 1 1 1 0 Utp14 protein SpaA PF17802.1 OEU20175.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.3 4 1 0 4 4 4 0 Prealbumin-like fold domain Hist_deacetyl PF00850.19 OEU20176.1 - 4.6e-35 121.6 0.0 6.3e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HA PF03457.14 OEU20177.1 - 3.2e-19 69.0 0.9 3e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Helicase associated domain DUF2284 PF10050.9 OEU20177.1 - 0.061 13.1 1.1 0.13 12.0 1.1 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) PHR PF08005.12 OEU20177.1 - 0.73 10.5 6.1 1.5 9.5 6.1 1.5 1 0 0 1 1 1 0 PHR domain U3_assoc_6 PF08640.11 OEU20178.1 - 4e-19 68.5 4.1 4e-19 68.5 4.1 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OEU20178.1 - 0.071 14.0 0.0 47 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 OEU20178.1 - 0.18 9.7 1.9 0.41 8.5 1.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RXT2_N PF08595.11 OEU20178.1 - 6.5 6.8 18.2 0.71 9.9 3.2 3.5 4 0 0 4 4 4 0 RXT2-like, N-terminal E1_DerP2_DerF2 PF02221.15 OEU20180.1 - 0.0018 18.7 0.0 0.0027 18.1 0.0 1.4 1 1 0 1 1 1 1 ML domain MttA_Hcf106 PF02416.16 OEU20181.1 - 0.54 9.6 2.3 3.7 6.9 0.2 2.6 3 0 0 3 3 3 0 mttA/Hcf106 family Ndc1_Nup PF09531.10 OEU20183.1 - 1 8.0 4.9 1.1 7.9 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NOA36 PF06524.12 OEU20183.1 - 9.1 5.5 15.2 24 4.1 15.2 1.6 1 0 0 1 1 1 0 NOA36 protein DUF16 PF01519.16 OEU20187.1 - 0.12 12.9 9.9 2.5 8.6 6.9 3.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 OEU20187.1 - 1.3 9.1 9.4 0.057 13.5 3.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 OEU20188.1 - 2.1e-24 85.9 0.2 5.8e-13 49.2 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU20188.1 - 7.3e-18 62.8 1.8 0.052 14.1 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OEU20188.1 - 1.9e-16 60.2 0.7 4.1e-05 24.0 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU20188.1 - 3.5e-16 59.1 3.4 6.3e-05 23.2 0.1 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OEU20188.1 - 1e-11 44.7 0.4 0.68 10.5 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat BUD22 PF09073.10 OEU20188.1 - 0.0029 17.0 7.2 0.0029 17.0 7.2 2.7 2 1 0 2 2 1 1 BUD22 IMUP PF15761.5 OEU20188.1 - 0.044 14.5 2.6 0.044 14.5 2.6 4.3 5 0 0 5 5 3 0 Immortalisation up-regulated protein DUF3446 PF11928.8 OEU20188.1 - 0.088 13.1 27.1 0.77 10.1 5.0 4.1 4 0 0 4 4 4 0 Early growth response N-terminal domain SR-25 PF10500.9 OEU20188.1 - 0.45 10.1 31.6 0.28 10.8 4.3 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4766 PF15973.5 OEU20188.1 - 1.3 9.6 10.8 3.6 8.2 0.0 4.0 5 1 0 5 5 4 0 Domain of unknown function (DUF4766) RNA_pol_3_Rpc31 PF11705.8 OEU20188.1 - 8.4 6.6 17.9 0.72 10.1 12.5 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 OEU20189.1 - 0.42 8.8 35.7 0.0058 15.0 8.2 3.6 5 0 0 5 5 5 0 CDC45-like protein CDT1_C PF16679.5 OEU20189.1 - 3.6 8.1 15.8 5.5 7.5 0.1 4.7 3 1 1 4 4 4 0 DNA replication factor Cdt1 C-terminal domain Patatin PF01734.22 OEU20190.1 - 6.8e-08 32.9 4.0 1.1e-07 32.3 0.5 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase Rad10 PF03834.14 OEU20191.1 - 1.1e-41 141.4 0.4 2.2e-41 140.5 0.4 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OEU20191.1 - 0.0011 19.5 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF496 PF04363.12 OEU20191.1 - 0.033 14.2 0.1 3.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF496) DUF1365 PF07103.11 OEU20191.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1365) NESP55 PF06390.12 OEU20191.1 - 5.9 6.4 13.5 11 5.5 13.5 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF1769 PF08588.10 OEU20193.1 - 0.043 14.0 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) PhyH PF05721.13 OEU20194.1 - 2e-16 60.9 0.0 1.3e-15 58.2 0.0 2.2 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) MS_channel PF00924.18 OEU20194.1 - 0.14 11.6 0.4 0.22 11.0 0.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF4611 PF15387.6 OEU20194.1 - 5.4 7.3 10.9 33 4.8 6.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Lectin_N PF03954.14 OEU20195.1 - 0.026 14.3 1.6 0.055 13.2 1.6 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2722 PF10846.8 OEU20195.1 - 0.1 11.5 4.7 0.19 10.6 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ODV-E18 PF10717.9 OEU20195.1 - 0.11 12.3 3.9 0.23 11.3 3.9 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF979 PF06166.12 OEU20195.1 - 0.12 11.5 0.8 0.19 10.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DUF4834 PF16118.5 OEU20195.1 - 0.15 13.0 6.9 0.044 14.7 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) RXT2_N PF08595.11 OEU20195.1 - 0.17 11.9 5.9 0.38 10.8 5.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal UL45 PF05473.12 OEU20195.1 - 0.6 9.7 3.1 1.1 8.9 3.1 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DNA_pol_phi PF04931.13 OEU20195.1 - 4.9 5.1 9.7 8.1 4.4 9.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3263 PF11662.8 OEU20196.1 - 0.015 15.2 0.2 0.015 15.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) DUF908 PF06012.12 OEU20196.1 - 0.025 14.0 7.6 0.03 13.7 7.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4919 PF16266.5 OEU20196.1 - 0.034 14.1 0.4 0.053 13.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) API5 PF05918.11 OEU20196.1 - 0.35 9.6 4.0 0.55 9.0 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4407 PF14362.6 OEU20196.1 - 0.69 9.2 7.9 0.85 8.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 OEU20196.1 - 0.82 8.7 5.7 0.94 8.5 5.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 OEU20196.1 - 2.1 7.9 22.3 3.3 7.3 22.3 1.5 1 1 0 1 1 1 0 Spt20 family Peptidase_S51 PF03575.17 OEU20198.1 - 2.5e-22 79.5 0.0 8.1e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S51 Ribosomal_S8e PF01201.22 OEU20198.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S8e CDC45 PF02724.14 OEU20198.1 - 0.63 8.3 3.2 0.93 7.7 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_16 PF10294.9 OEU20200.1 - 1.3e-22 80.4 0.1 2.1e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 OEU20200.1 - 2.4e-05 23.9 0.2 4.1e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OEU20200.1 - 0.002 17.6 0.6 0.0036 16.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 OEU20200.1 - 0.028 13.7 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G WD40_4 PF16300.5 OEU20203.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Type of WD40 repeat HA PF03457.14 OEU20205.1 - 1.3e-42 144.0 11.9 2e-18 66.5 3.8 3.1 3 0 0 3 3 3 3 Helicase associated domain Ribosomal_L7Ae PF01248.26 OEU20205.1 - 0.005 16.5 0.0 9.8 6.0 0.0 3.1 3 0 0 3 3 3 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SASA PF03629.18 OEU20207.1 - 2.5e-10 40.4 3.9 7.2e-06 25.8 2.2 4.1 2 1 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase DUF1902 PF08972.11 OEU20207.1 - 0.027 14.5 0.0 0.097 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) F-box-like PF12937.7 OEU20208.1 - 8.5e-05 22.4 0.0 0.00028 20.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU20208.1 - 0.00081 19.2 0.0 0.0027 17.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain SR-25 PF10500.9 OEU20209.1 - 1.7 8.2 15.2 2.7 7.5 4.3 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.27 OEU20210.1 - 1e-20 73.4 0.7 3e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein ERF PF04404.12 OEU20210.1 - 1.3 8.8 4.8 2.7 7.8 4.8 1.5 1 1 0 1 1 1 0 ERF superfamily ECH_1 PF00378.20 OEU20211.1 - 1.8e-49 168.3 0.0 2.2e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU20211.1 - 9.4e-17 61.5 0.0 1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PT PF04886.12 OEU20212.1 - 2.2e-13 49.5 36.6 0.0012 18.3 36.6 2.3 1 1 0 1 1 1 1 PT repeat Glycoprotein_G PF00802.19 OEU20212.1 - 0.15 11.4 9.3 0.2 11.0 9.3 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G zf-MYND PF01753.18 OEU20214.1 - 7.6e-07 29.1 13.2 1.6e-06 28.1 13.2 1.5 1 0 0 1 1 1 1 MYND finger IBR PF01485.21 OEU20217.1 - 0.0019 18.3 12.4 0.0019 18.3 12.4 6.1 3 2 2 5 5 5 1 IBR domain, a half RING-finger domain TssO PF17561.2 OEU20217.1 - 0.0037 17.4 0.2 0.098 12.8 0.0 2.9 2 0 0 2 2 2 1 Type VI secretion system, TssO zf-RING_UBOX PF13445.6 OEU20217.1 - 0.011 15.8 6.0 0.011 15.8 6.0 4.9 5 1 0 5 5 5 0 RING-type zinc-finger DUF4083 PF13314.6 OEU20217.1 - 0.024 14.6 0.2 0.091 12.7 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) CLN3 PF02487.17 OEU20217.1 - 0.15 11.0 2.4 11 5.0 0.0 3.1 3 0 0 3 3 3 0 CLN3 protein Complex1_LYR PF05347.15 OEU20218.1 - 1.3e-10 41.2 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Pkinase PF00069.25 OEU20221.1 - 2.9e-74 249.7 0.0 3.4e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20221.1 - 9.6e-33 113.6 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU20221.1 - 0.00032 20.1 0.1 0.038 13.3 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OEU20221.1 - 0.0027 16.7 0.0 0.032 13.2 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OEU20221.1 - 0.025 14.5 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family tRNA-synt_1c PF00749.21 OEU20222.1 - 3.6e-85 285.6 0.2 7.4e-85 284.6 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OEU20222.1 - 7.4e-34 117.1 0.7 2e-33 115.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Trypan_glycop_C PF10659.9 OEU20223.1 - 5.5 7.4 21.8 8.4 6.8 7.2 2.5 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain ARD PF03079.14 OEU20225.1 - 3.6e-27 95.5 0.6 5e-27 95.0 0.6 1.3 1 1 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OEU20225.1 - 1.3e-08 34.4 0.1 1.9e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OEU20225.1 - 0.00039 20.3 0.1 0.00058 19.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain DDE_Tnp_1_7 PF13843.6 OEU20226.1 - 1.1e-13 51.2 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Gly_transf_sug PF04488.15 OEU20229.1 - 5.5e-10 39.7 0.2 2.5e-09 37.6 0.2 2.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Sulfotransfer_2 PF03567.14 OEU20229.1 - 3.1e-06 27.3 3.5 3.1e-06 27.3 3.5 3.3 2 1 0 2 2 2 1 Sulfotransferase family Methyltransf_12 PF08242.12 OEU20229.1 - 5.8 7.7 7.4 13 6.6 0.0 4.1 4 0 0 4 4 4 0 Methyltransferase domain Band_3_cyto PF07565.13 OEU20229.1 - 7.6 6.2 10.5 0.41 10.4 4.0 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Renin_r PF07850.14 OEU20229.1 - 9.3 6.9 7.6 13 6.5 0.6 3.4 2 1 0 2 2 2 0 Renin receptor-like protein zf-MYND PF01753.18 OEU20230.1 - 2.5e-09 37.0 15.3 6.9e-09 35.7 15.3 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OEU20230.1 - 1.6 9.1 9.8 4.6 7.6 9.8 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Glyco_hydro_2_C PF02836.17 OEU20231.1 - 8.1e-22 77.7 0.1 4e-19 68.8 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 OEU20231.1 - 2e-07 30.8 0.0 4.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 OEU20231.1 - 0.0039 17.1 1.1 0.033 14.1 0.2 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OEU20231.1 - 0.0045 17.6 0.1 0.019 15.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 TAP35_44 PF07265.11 OEU20231.1 - 0.028 14.4 0.0 0.084 12.9 0.0 1.9 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 TALPID3 PF15324.6 OEU20231.1 - 0.16 9.6 0.6 0.27 8.9 0.6 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Mannosyl_trans3 PF11051.8 OEU20232.1 - 0.037 13.4 0.2 0.064 12.6 0.2 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative GAGA_bind PF06217.12 OEU20234.1 - 1.8 8.8 21.6 2.6 8.2 21.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CCSAP PF15748.5 OEU20234.1 - 4.9 7.3 25.1 6.6 6.8 25.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Methyltransf_21 PF05050.12 OEU20235.1 - 1.3e-05 25.3 0.1 4.9e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF4834 PF16118.5 OEU20235.1 - 0.061 14.3 0.9 0.061 14.3 0.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF938 PF06080.12 OEU20236.1 - 6.3e-44 150.2 0.7 1.3e-42 145.9 0.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF938) DUF2718 PF10918.8 OEU20236.1 - 0.007 16.9 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2718) Methyltransf_23 PF13489.6 OEU20236.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OEU20236.1 - 0.025 14.0 0.2 0.097 12.1 0.2 1.8 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 OEU20236.1 - 0.097 13.4 0.2 0.62 10.8 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain TPM_phosphatase PF04536.14 OEU20237.1 - 9.5e-09 35.5 3.8 1.5e-08 34.8 0.0 3.0 3 0 0 3 3 3 1 TPM domain Prok-RING_4 PF14447.6 OEU20237.1 - 3.6e-07 29.9 8.1 5.1e-06 26.2 4.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OEU20237.1 - 5.3e-06 26.2 9.3 2.6e-05 24.0 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU20237.1 - 5.8e-06 26.5 10.9 0.00013 22.3 6.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OEU20237.1 - 1.7e-05 24.7 6.2 4.1e-05 23.4 3.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU20237.1 - 0.00012 21.9 8.7 0.00019 21.2 5.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU20237.1 - 0.0032 17.6 6.2 0.0032 17.6 6.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OEU20237.1 - 0.013 15.3 11.2 0.046 13.6 7.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU20237.1 - 0.057 13.5 12.7 0.33 11.0 5.5 3.2 2 1 1 3 3 3 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU20237.1 - 0.12 12.4 4.8 0.059 13.4 2.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OEU20237.1 - 0.29 11.0 9.2 0.11 12.3 5.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OEU20237.1 - 0.57 10.5 3.1 3.6 8.0 1.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 OEU20237.1 - 1.1 9.1 5.2 9.3 6.1 0.1 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-rbx1 PF12678.7 OEU20237.1 - 2 8.8 11.0 1.2 9.5 7.2 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 OEU20237.1 - 8 6.4 6.1 6.6 6.7 3.2 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) 7tm_3 PF00003.22 OEU20240.1 - 2.9e-23 82.8 23.5 2.9e-23 82.8 23.5 1.6 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR DUF4813 PF16072.5 OEU20241.1 - 0.0066 16.2 6.9 0.012 15.3 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) DUF4448 PF14610.6 OEU20241.1 - 0.0078 16.0 2.4 0.018 14.9 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) 2-Hacid_dh_C PF02826.19 OEU20242.1 - 3.2e-33 114.6 0.0 4.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CLPTM1 PF05602.12 OEU20243.1 - 0.028 13.4 0.6 0.038 13.0 0.6 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Tctex-1 PF03645.13 OEU20244.1 - 0.034 14.4 0.4 0.073 13.3 0.4 1.6 1 0 0 1 1 1 0 Tctex-1 family Pox_Ag35 PF03286.14 OEU20244.1 - 0.17 11.6 16.0 1.4 8.7 6.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein AP3D1 PF06375.11 OEU20244.1 - 2.5 8.3 16.8 0.058 13.6 9.7 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Epimerase PF01370.21 OEU20249.1 - 1.8e-18 66.9 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU20249.1 - 2.4e-11 43.2 0.0 5.2e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OEU20249.1 - 2.9e-09 36.5 0.0 4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OEU20249.1 - 4.4e-08 32.9 0.0 8.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OEU20249.1 - 9.1e-07 28.9 0.0 2.1e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU20249.1 - 4.2e-06 26.5 0.1 0.00055 19.6 0.0 2.4 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 OEU20249.1 - 0.00062 19.3 0.2 0.5 9.8 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.17 OEU20249.1 - 0.031 13.4 0.1 0.076 12.1 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 OEU20249.1 - 0.06 13.2 0.2 0.2 11.5 0.2 1.8 1 1 0 1 1 1 0 KR domain LRR_4 PF12799.7 OEU20250.1 - 0.0021 18.4 7.4 0.42 11.1 0.4 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU20250.1 - 0.11 12.3 1.0 8.9 6.2 0.0 3.2 2 1 0 2 2 2 0 Leucine rich repeat C1_2 PF03107.16 OEU20251.1 - 0.51 10.7 8.3 2.3 8.6 0.1 3.9 3 0 0 3 3 3 0 C1 domain Gly_transf_sug PF04488.15 OEU20252.1 - 1.7e-08 35.0 0.2 5.3e-08 33.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU20252.1 - 0.0013 18.2 0.2 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain ThiD2 PF17792.1 OEU20252.1 - 0.073 13.5 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 ThiD2 family Aa_trans PF01490.18 OEU20253.1 - 7.3e-35 120.5 7.4 8.4e-35 120.3 7.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU20253.1 - 0.0038 16.3 2.7 0.0057 15.7 2.7 1.3 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF2516 PF10724.9 OEU20253.1 - 6.9 7.0 7.7 0.53 10.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Mucin PF01456.17 OEU20255.1 - 3.1 7.8 27.9 0.73 9.8 21.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Cytochrom_B561 PF03188.16 OEU20256.1 - 0.0065 16.6 2.9 0.19 11.9 0.3 2.3 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 Phage_holin_1 PF04531.13 OEU20256.1 - 0.025 15.1 1.7 0.038 14.5 0.8 1.7 2 0 0 2 2 2 0 Bacteriophage holin TPR_2 PF07719.17 OEU20257.1 - 0.0065 16.5 0.0 2.6 8.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU20257.1 - 0.023 14.5 0.7 7.7 6.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OEU20257.1 - 0.042 14.1 0.0 7.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ZU5 PF00791.20 OEU20257.1 - 0.065 13.6 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 ZU5 domain TFIIA PF03153.13 OEU20257.1 - 0.18 11.7 10.3 0.23 11.4 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5531 PF17671.1 OEU20257.1 - 4.6 7.1 8.0 1.4 8.8 0.7 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5531) Ribosomal_L17 PF01196.19 OEU20258.1 - 9.7e-33 113.0 0.8 1.6e-32 112.3 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Macro PF01661.21 OEU20258.1 - 0.058 13.5 0.4 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Macro domain DALR_1 PF05746.15 OEU20258.1 - 0.068 13.4 1.2 0.081 13.1 0.1 1.7 2 0 0 2 2 2 0 DALR anticodon binding domain Cu2_monooxygen PF01082.20 OEU20259.1 - 7.7e-12 45.6 0.0 1.7e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OEU20259.1 - 3.7e-11 42.8 1.2 1e-07 31.6 0.1 3.1 3 0 0 3 3 3 2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain ShK PF01549.24 OEU20259.1 - 0.0041 17.6 0.4 0.017 15.7 0.4 2.1 1 0 0 1 1 1 1 ShK domain-like TpcC PF12642.7 OEU20259.1 - 0.029 14.2 0.6 0.063 13.1 0.6 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TcpC PBP1_TM PF14812.6 OEU20259.1 - 6.9 7.1 9.4 12 6.4 3.2 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 OEU20260.1 - 1e-26 94.0 3.0 1e-26 94.0 3.0 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter SGTA_dimer PF16546.5 OEU20262.1 - 0.06 13.1 0.2 0.23 11.3 0.4 1.9 2 0 0 2 2 2 0 Homodimerisation domain of SGTA Stealth_CR1 PF17101.5 OEU20263.1 - 5.1 6.9 7.0 0.37 10.6 1.6 1.9 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 DUF2981 PF11200.8 OEU20264.1 - 2.4 7.8 5.4 4.5 6.9 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) LRR_8 PF13855.6 OEU20265.1 - 3.2e-07 30.0 5.0 0.02 14.7 0.0 4.3 3 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OEU20265.1 - 5.3e-07 29.9 5.4 0.18 12.3 0.1 4.3 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU20265.1 - 1.3e-05 25.0 6.2 5.5 8.0 0.0 6.1 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 OEU20265.1 - 0.00048 20.0 1.0 5 7.4 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeat Glutaredoxin2_C PF04399.13 OEU20266.1 - 5.6e-11 42.4 0.3 1e-10 41.6 0.2 1.5 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 OEU20266.1 - 0.00028 21.2 0.2 0.0022 18.3 0.2 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU20266.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LRR_4 PF12799.7 OEU20267.1 - 2.9e-16 59.3 21.8 0.00078 19.8 0.9 5.9 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU20267.1 - 1.1e-14 54.0 13.7 1.2e-07 31.3 0.7 4.1 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 OEU20267.1 - 1.4e-13 49.3 15.0 0.51 11.1 0.1 8.0 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.6 OEU20267.1 - 0.00017 21.3 17.6 0.6 10.3 0.2 5.8 6 0 0 6 6 6 4 Leucine Rich repeat Spo7_2_N PF15407.6 OEU20267.1 - 0.023 14.3 0.7 0.63 9.7 0.6 2.7 2 0 0 2 2 2 0 Sporulation protein family 7 p450 PF00067.22 OEU20270.1 - 5.9e-69 233.0 0.0 8.6e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OEU20270.1 - 9.6e-28 97.3 0.0 1.9e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OEU20270.1 - 1.1e-18 67.8 0.0 2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OEU20270.1 - 6.6e-17 62.1 0.0 1.5e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Mito_carr PF00153.27 OEU20271.1 - 2.8e-17 62.4 1.4 1.3e-07 31.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein HA PF03457.14 OEU20272.1 - 6.2e-18 64.9 0.4 1e-14 54.6 0.1 2.1 2 0 0 2 2 2 2 Helicase associated domain Sulfotransfer_1 PF00685.27 OEU20273.1 - 6.5e-34 117.6 0.5 1.1e-33 116.8 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU20273.1 - 2.4e-10 41.1 0.0 2.6e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OEU20273.1 - 0.00053 20.0 0.4 0.0012 18.9 0.4 1.7 1 1 0 1 1 1 1 Sulfotransferase family Vsr PF03852.15 OEU20274.1 - 0.045 13.6 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr FKBP_C PF00254.28 OEU20275.1 - 9.5e-08 32.3 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LRR_4 PF12799.7 OEU20277.1 - 2e-12 47.1 18.7 6.4e-05 23.3 5.6 5.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU20277.1 - 5.7e-11 42.0 14.3 0.00069 19.3 0.2 4.2 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 OEU20277.1 - 3.8e-10 38.9 14.2 0.79 10.5 0.1 7.3 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 OEU20277.1 - 0.42 10.8 15.6 12 6.3 0.4 6.0 7 0 0 7 7 7 0 Leucine Rich repeat Nitroreductase PF00881.24 OEU20278.1 - 2.1e-11 44.2 0.0 6.1e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Nitroreductase family Zip PF02535.22 OEU20278.1 - 0.14 11.4 2.3 0.17 11.0 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OEU20278.1 - 0.71 8.6 5.2 1.2 7.8 5.2 1.5 1 0 0 1 1 1 0 Presenilin Mlh1_C PF16413.5 OEU20278.1 - 1.1 8.5 0.0 1.1 8.5 0.0 2.2 1 1 1 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus SR-25 PF10500.9 OEU20278.1 - 4.4 6.9 14.7 0.37 10.4 10.1 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein UPF0242 PF06785.11 OEU20279.1 - 0.24 11.5 5.9 0.42 10.7 5.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 OEU20279.1 - 1.9 9.0 18.1 18 5.9 13.2 3.0 2 1 0 2 2 2 0 Cell division protein ZapB CPDase PF07823.11 OEU20280.1 - 2.5e-06 27.3 0.2 2.5e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein KASH PF10541.9 OEU20280.1 - 0.11 12.7 0.9 0.41 11.0 0.9 2.0 1 0 0 1 1 1 0 Nuclear envelope localisation domain RSN1_7TM PF02714.15 OEU20281.1 - 1.3e-13 50.9 6.9 3.1e-13 49.7 6.9 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OEU20281.1 - 0.0002 21.1 0.5 0.0002 21.1 0.5 3.5 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport Zn_clus PF00172.18 OEU20282.1 - 6.5e-05 23.0 10.0 0.00015 21.8 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 OEU20283.1 - 1.3e-66 224.7 0.0 2.8e-66 223.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20283.1 - 1.7e-39 135.7 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU20283.1 - 2.7e-06 27.5 0.0 4.8e-05 23.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU20283.1 - 8.8e-05 21.4 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU20283.1 - 0.00089 18.7 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU20283.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OEU20283.1 - 0.0056 16.3 0.2 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Cauli_DNA-bind PF03310.13 OEU20283.1 - 0.026 14.6 0.3 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Cytochrom_B561 PF03188.16 OEU20284.1 - 2e-10 41.0 12.8 6.3e-07 29.6 3.9 2.7 3 0 0 3 3 3 2 Eukaryotic cytochrome b561 DUF3681 PF12442.8 OEU20284.1 - 0.0076 16.7 7.1 0.47 10.9 0.8 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3681) DoxX_3 PF13781.6 OEU20284.1 - 0.039 14.6 0.9 0.039 14.6 0.9 2.6 2 1 1 3 3 3 0 DoxX-like family DUF3671 PF12420.8 OEU20284.1 - 0.081 13.0 7.7 2.2 8.4 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function Orf78 PF06024.12 OEU20284.1 - 0.26 11.6 6.0 7.7 6.9 0.2 3.2 3 0 0 3 3 3 0 Orf78 (ac78) DUF2569 PF10754.9 OEU20284.1 - 0.27 11.7 15.8 0.051 14.0 3.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) DUF4231 PF14015.6 OEU20284.1 - 0.77 10.3 0.0 0.77 10.3 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF4231) NB PF04159.13 OEU20284.1 - 2.8 8.0 9.1 2.8 8.0 0.6 2.9 3 0 0 3 3 3 0 NB glycoprotein Asp PF00026.23 OEU20285.1 - 5.5e-43 147.6 0.1 3.5e-20 72.7 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OEU20285.1 - 0.00014 22.1 0.2 0.00014 22.1 0.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Stevor PF17410.2 OEU20285.1 - 0.0083 15.7 3.6 0.027 14.0 0.0 2.6 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame DUF2681 PF10883.8 OEU20285.1 - 0.037 14.4 0.2 0.037 14.4 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) MLANA PF14991.6 OEU20285.1 - 0.059 13.7 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Pox_EPC_I2-L1 PF12575.8 OEU20285.1 - 0.14 12.4 1.0 19 5.6 0.0 2.8 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 RCR PF12273.8 OEU20285.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.2 4 0 0 4 4 4 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 OEU20285.1 - 0.62 11.0 0.0 0.62 11.0 0.0 2.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4446 PF14584.6 OEU20285.1 - 1.8 8.5 7.5 19 5.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) RIFIN PF02009.16 OEU20285.1 - 6 6.7 7.5 0.32 10.8 0.1 2.4 3 1 0 3 3 3 0 Rifin ADH_N PF08240.12 OEU20286.1 - 2.1e-24 85.5 4.6 4.2e-24 84.5 4.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OEU20286.1 - 5.8e-22 78.1 0.6 5.8e-22 78.1 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OEU20286.1 - 2.4e-06 27.0 0.2 4.3e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 OEU20286.1 - 0.00084 18.9 1.0 0.0014 18.2 1.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OEU20286.1 - 0.001 18.4 2.7 0.0011 18.3 1.6 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 OEU20286.1 - 0.0024 18.0 2.5 0.0057 16.8 2.5 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N_2 PF13602.6 OEU20286.1 - 0.014 16.5 0.0 0.024 15.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_trans_4_5 PF16994.5 OEU20286.1 - 0.17 11.5 0.3 0.28 10.8 0.3 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Sugar_tr PF00083.24 OEU20287.1 - 1.9e-34 119.4 10.4 1.5e-33 116.4 10.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU20287.1 - 7.2e-28 97.5 19.1 8.9e-28 97.2 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily rve_3 PF13683.6 OEU20288.1 - 0.012 15.3 4.9 0.36 10.6 0.4 3.3 3 0 0 3 3 3 0 Integrase core domain ATP1G1_PLM_MAT8 PF02038.16 OEU20288.1 - 9.8 5.7 7.5 6 6.4 1.3 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DHH PF01368.20 OEU20289.1 - 0.005 17.1 0.1 0.031 14.5 0.1 2.4 1 0 0 1 1 1 1 DHH family SHOCT PF09851.9 OEU20289.1 - 0.93 9.3 5.1 0.17 11.7 0.6 2.2 2 0 0 2 2 2 0 Short C-terminal domain RNA_helicase PF00910.22 OEU20290.1 - 0.38 11.2 3.2 5 7.6 0.4 2.5 2 0 0 2 2 2 0 RNA helicase EBP50_C PF09007.11 OEU20290.1 - 0.48 11.4 4.2 0.28 12.2 0.7 2.2 2 0 0 2 2 2 0 EBP50, C-terminal AMP-binding PF00501.28 OEU20291.1 - 1e-89 301.1 0.0 1.4e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2407_C PF13373.6 OEU20293.1 - 0.61 10.3 6.6 0.54 10.4 0.3 3.5 4 0 0 4 4 4 0 DUF2407 C-terminal domain Zip PF02535.22 OEU20293.1 - 2.7 7.1 5.5 1.2 8.3 0.1 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter WW PF00397.26 OEU20294.1 - 2.5e-19 69.0 4.1 2.6e-10 40.2 0.3 2.2 2 0 0 2 2 2 2 WW domain DUF4585 PF15232.6 OEU20294.1 - 0.022 14.8 0.8 4.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) Glyco_hyd_101C PF17451.2 OEU20294.1 - 0.16 12.3 1.6 13 6.1 1.6 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain PRIMA1 PF16101.5 OEU20295.1 - 2.5 8.2 10.2 0.11 12.6 2.6 2.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DAZAP2 PF11029.8 OEU20295.1 - 8.1 7.4 12.3 0.37 11.7 1.6 2.9 3 0 0 3 3 3 0 DAZ associated protein 2 (DAZAP2) Ribosomal_L36e PF01158.18 OEU20297.1 - 4.7e-09 36.4 0.3 2.5e-07 30.8 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L36e Sec16_C PF12931.7 OEU20297.1 - 0.042 13.5 1.3 0.09 12.4 1.3 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 zf-CCHC PF00098.23 OEU20298.1 - 0.015 15.3 3.4 0.04 14.0 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OEU20298.1 - 0.3 11.1 3.3 0.93 9.5 3.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Utp14 PF04615.13 OEU20298.1 - 1.3 7.5 21.3 0.52 8.8 8.6 2.2 2 0 0 2 2 2 0 Utp14 protein zf-CCHC_2 PF13696.6 OEU20298.1 - 3.6 7.5 6.7 0.68 9.8 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle SDA1 PF05285.12 OEU20298.1 - 9.3 5.6 37.1 1.8 7.9 27.8 2.5 2 0 0 2 2 2 0 SDA1 DUF4589 PF15252.6 OEU20299.1 - 0.13 12.2 0.7 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) MGC-24 PF05283.11 OEU20299.1 - 0.14 12.6 4.9 1.2 9.5 0.4 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Nucleotid_trans PF03407.16 OEU20300.1 - 3.3e-24 86.1 1.6 5.5e-24 85.3 1.6 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase FAM176 PF14851.6 OEU20301.1 - 0.018 14.7 0.2 0.018 14.7 0.2 3.3 1 1 2 3 3 3 0 FAM176 family SURF2 PF05477.11 OEU20301.1 - 3.9 7.1 13.2 5.4 6.6 13.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Glyco_hydro81C PF17652.1 OEU20302.1 - 2.1e-11 43.7 0.0 2.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Dirigent PF03018.14 OEU20303.1 - 0.0095 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Dirigent-like protein zf-PARP PF00645.18 OEU20304.1 - 3.3e-14 53.5 12.3 2.4e-09 37.9 0.4 4.0 3 1 1 4 4 4 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region YgbA_NO PF11756.8 OEU20304.1 - 0.25 11.7 4.8 1.5 9.2 0.1 3.0 3 0 0 3 3 3 0 Nitrous oxide-stimulated promoter CDC45 PF02724.14 OEU20304.1 - 0.56 8.4 21.1 1.1 7.5 1.7 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF3810 PF12725.7 OEU20307.1 - 0.13 11.6 0.2 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Kinesin_assoc PF16183.5 OEU20307.1 - 0.89 9.7 5.4 0.46 10.6 3.1 1.8 1 1 1 2 2 2 0 Kinesin-associated Cupin_4 PF08007.12 OEU20308.1 - 1.2e-23 84.2 0.0 3.5e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU20308.1 - 9.8e-05 22.2 2.3 0.00013 21.7 0.0 2.2 2 2 0 2 2 2 1 Cupin-like domain Cupin_1 PF00190.22 OEU20308.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Cupin COesterase PF00135.28 OEU20311.1 - 4.1e-55 187.6 0.8 4.7e-55 187.4 0.8 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OEU20311.1 - 1.2e-06 28.5 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU20311.1 - 0.0027 17.2 0.1 0.0034 16.9 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family ShK PF01549.24 OEU20312.1 - 0.0078 16.7 19.0 0.011 16.2 6.5 3.3 2 2 0 2 2 2 2 ShK domain-like PT PF04886.12 OEU20312.1 - 0.38 10.3 45.0 0.044 13.3 29.9 3.0 3 0 0 3 3 3 0 PT repeat SASA PF03629.18 OEU20314.1 - 3.9e-11 43.0 0.0 6e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF3336 PF11815.8 OEU20314.1 - 1.1 9.0 6.7 12 5.7 2.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3336) PTPRCAP PF15713.5 OEU20315.1 - 9.1 6.6 24.4 13 6.1 17.7 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF676 PF05057.14 OEU20316.1 - 0.039 13.5 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) tRNA_NucTran2_2 PF13735.6 OEU20317.1 - 0.02 14.9 6.8 1 9.3 1.5 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative ATP_bind_3 PF01171.20 OEU20318.1 - 1.4e-16 60.8 0.0 3.2e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 OEU20318.1 - 0.00046 20.3 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SpoU_methylase PF00588.19 OEU20319.1 - 3.6e-14 53.1 0.0 5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF4589 PF15252.6 OEU20319.1 - 0.0054 16.8 0.8 0.0074 16.3 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) UspA1_rep PF18792.1 OEU20320.1 - 0.00015 22.0 48.0 0.21 12.2 0.1 9.1 9 0 0 9 9 9 6 Ubiquitous surface protein adhesin repeat YadA_head PF05658.14 OEU20320.1 - 0.2 12.1 6.2 0.48 10.9 0.0 4.1 5 0 0 5 5 5 0 Head domain of trimeric autotransporter adhesin Kelch_6 PF13964.6 OEU20320.1 - 0.43 11.0 2.3 13 6.2 0.1 3.3 4 0 0 4 4 4 0 Kelch motif Rota_NS26 PF01525.16 OEU20321.1 - 0.048 13.7 0.6 0.06 13.3 0.6 1.3 1 0 0 1 1 1 0 Rotavirus NS26 Raffinose_syn PF05691.12 OEU20321.1 - 0.062 11.1 0.1 0.06 11.1 0.1 1.0 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 SLATT_5 PF18160.1 OEU20322.1 - 0.0017 17.7 1.2 0.0024 17.2 0.6 1.6 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 SLATT_4 PF18186.1 OEU20322.1 - 0.0018 17.9 0.2 0.0045 16.6 0.2 1.7 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 TAP_C PF03943.13 OEU20322.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 TAP C-terminal domain DUF4231 PF14015.6 OEU20322.1 - 0.46 11.0 2.3 2.5 8.6 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2185 PF09951.9 OEU20323.1 - 0.0098 15.7 1.6 0.075 12.9 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2185) FTCD_C PF04961.12 OEU20323.1 - 0.036 13.8 0.2 0.62 9.8 0.0 2.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Serinc PF03348.15 OEU20323.1 - 1.9 7.4 6.6 4.3 6.2 6.6 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) NiFe_hyd_3_EhaA PF17367.2 OEU20325.1 - 0.017 15.2 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A Sulfatase PF00884.23 OEU20326.1 - 8.1e-49 166.7 0.2 5.1e-48 164.1 0.2 2.2 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OEU20326.1 - 0.0063 17.2 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 OEU20326.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Phosphodiest PF01663.22 OEU20326.1 - 0.084 12.5 0.2 2.1 7.9 0.1 2.7 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Lactonase PF10282.9 OEU20328.1 - 0.0088 15.3 0.0 0.019 14.2 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OEU20328.1 - 0.015 14.9 0.1 5.4 6.5 0.1 3.1 1 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region TSP_1 PF00090.19 OEU20328.1 - 0.05 13.8 6.2 0.16 12.2 6.2 1.9 1 0 0 1 1 1 0 Thrombospondin type 1 domain Arylesterase PF01731.20 OEU20328.1 - 0.12 12.6 0.0 0.8 9.9 0.0 2.5 3 0 0 3 3 3 0 Arylesterase RHD3 PF05879.12 OEU20329.1 - 8.9e-05 20.8 4.1 0.00012 20.4 4.1 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Peptidase_M15_3 PF08291.11 OEU20329.1 - 0.1 12.7 0.1 1.4 9.0 0.0 2.5 2 1 0 2 2 2 0 Peptidase M15 DNA_pol3_tau_4 PF12168.8 OEU20329.1 - 0.11 13.0 0.8 0.28 11.7 0.8 1.7 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding DUF5344 PF17279.2 OEU20329.1 - 0.45 11.1 9.0 4.5 7.9 3.0 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Pet191_N PF10203.9 OEU20330.1 - 1.9e-17 63.3 6.2 2.1e-17 63.2 6.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Ank_4 PF13637.6 OEU20331.1 - 2.8e-15 56.4 0.3 1.5e-05 25.4 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU20331.1 - 1e-12 48.0 0.0 2.6e-06 27.6 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU20331.1 - 5e-12 46.3 0.0 2.1e-05 25.0 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU20331.1 - 2e-10 40.0 0.5 0.00011 22.3 0.0 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 OEU20331.1 - 8.1e-08 32.4 0.1 0.01 16.2 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeat Reo_sigmaC PF04582.12 OEU20332.1 - 0.05 13.9 1.1 0.099 12.9 0.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain SGS PF05002.15 OEU20334.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.7 3 0 0 3 3 3 0 SGS domain BTB PF00651.31 OEU20335.1 - 6.4e-13 48.9 0.3 9.1e-12 45.2 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 OEU20335.1 - 6.4e-06 26.3 1.3 2.3e-05 24.5 0.2 2.3 2 0 0 2 2 2 1 MATH domain SAP PF02037.27 OEU20335.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 SAP domain Esterase PF00756.20 OEU20336.1 - 9.7e-32 110.6 0.0 2.8e-31 109.1 0.0 1.8 1 1 0 1 1 1 1 Putative esterase ADH_zinc_N PF00107.26 OEU20336.1 - 2.5e-23 82.5 0.1 5.2e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU20336.1 - 4.8e-17 61.8 3.6 9.8e-17 60.8 3.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OEU20336.1 - 0.018 14.3 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OEU20336.1 - 0.18 11.2 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PP2C PF00481.21 OEU20337.1 - 5.3e-43 147.5 0.1 6e-43 147.3 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU20337.1 - 0.00083 19.1 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU20337.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF4298 PF14131.6 OEU20337.1 - 0.26 11.3 0.1 0.37 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) zf-met2 PF12907.7 OEU20338.1 - 2.8e-12 46.6 0.5 4.4e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding AAA_33 PF13671.6 OEU20339.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mon1 PF03164.14 OEU20339.1 - 0.065 12.3 0.6 0.092 11.8 0.6 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 ATC_hydrolase PF14196.6 OEU20339.1 - 0.099 13.4 0.2 0.099 13.4 0.2 2.1 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase GLTSCR1 PF15249.6 OEU20339.1 - 0.53 10.7 3.4 0.22 12.0 0.4 1.8 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein TMEM70 PF06979.12 OEU20340.1 - 0.00024 21.5 3.6 0.043 14.2 2.1 2.3 2 0 0 2 2 2 2 Assembly, mitochondrial proton-transport ATP synth complex FAM176 PF14851.6 OEU20340.1 - 0.077 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Iron_traffic PF04362.14 OEU20344.1 - 0.054 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking TPR_12 PF13424.6 OEU20345.1 - 0.078 13.3 0.0 4.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BOP1NT PF08145.12 OEU20347.1 - 1.7e-87 293.7 1.2 2.3e-87 293.2 1.2 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OEU20347.1 - 8e-23 80.3 0.5 0.00028 21.6 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20347.1 - 6.2e-11 42.5 0.0 4.9e-05 23.6 0.0 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OEU20349.1 - 1.2e-24 87.2 0.0 4.6e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU20349.1 - 0.00013 21.7 0.1 0.00031 20.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_25 PF13481.6 OEU20349.1 - 0.03 13.9 0.6 0.85 9.2 0.3 2.1 1 1 1 2 2 2 0 AAA domain DREPP PF05558.12 OEU20350.1 - 0.11 12.3 0.7 0.36 10.7 0.7 1.8 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide FlbD PF06289.11 OEU20350.1 - 0.31 10.7 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins Hid1 PF12722.7 OEU20351.1 - 1.6 6.7 18.9 2.5 6.1 18.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 OEU20351.1 - 9 6.8 19.5 17 5.9 19.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein MMR1 PF08505.10 OEU20351.1 - 9.3 6.5 30.7 18 5.5 30.7 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DEAD PF00270.29 OEU20353.1 - 1e-17 64.5 0.0 2.4e-17 63.3 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OEU20353.1 - 9.1e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OEU20353.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OEU20353.1 - 0.051 13.5 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OEU20353.1 - 0.054 13.8 0.0 0.23 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain DUF3638 PF12340.8 OEU20353.1 - 0.077 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Helicase_RecD PF05127.14 OEU20353.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Helicase HEPN_RES_NTD1 PF18870.1 OEU20353.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 AAA_19 PF13245.6 OEU20353.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CENP-B_dimeris PF09026.10 OEU20354.1 - 0.3 11.5 3.1 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MWFE PF15879.5 OEU20354.1 - 1.5 9.0 3.3 7.8 6.8 0.1 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit PBP1_TM PF14812.6 OEU20354.1 - 3.9 7.9 11.3 6.6 7.2 0.1 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0767 PF15990.5 OEU20354.1 - 4.5 7.5 6.7 2.3 8.4 0.4 2.9 3 0 0 3 3 3 0 UPF0767 family RNase_PH PF01138.21 OEU20355.1 - 1.1e-08 35.7 0.1 1.9e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OEU20355.1 - 0.011 15.7 0.1 0.035 14.1 0.0 1.9 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 PAP_assoc PF03828.19 OEU20356.1 - 3.5e-10 39.9 0.5 1.1e-09 38.4 0.6 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OEU20356.1 - 1.3e-08 35.0 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OEU20356.1 - 3.4e-05 23.8 0.0 7.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase KH_1 PF00013.29 OEU20357.1 - 2.9e-44 148.7 5.6 3.5e-15 55.6 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OEU20357.1 - 5.1e-12 45.4 0.9 0.00082 19.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OEU20357.1 - 2.8e-08 33.5 0.8 0.22 11.4 0.0 3.5 3 0 0 3 3 3 3 KH domain WW PF00397.26 OEU20357.1 - 1.6e-07 31.3 1.2 3.1e-07 30.3 1.2 1.5 1 0 0 1 1 1 1 WW domain MOEP19 PF16005.5 OEU20357.1 - 0.0029 17.6 0.0 0.67 10.0 0.1 2.7 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 OEU20357.1 - 0.91 9.6 2.5 6.2 7.0 0.1 2.8 3 0 0 3 3 3 0 NusA-like KH domain RRM_1 PF00076.22 OEU20358.1 - 2.4e-77 254.7 0.8 2.2e-21 75.5 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OEU20358.1 - 1.3e-32 111.7 0.5 5.1e-31 106.7 0.8 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 OEU20358.1 - 0.0011 19.1 0.0 17 5.6 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OEU20358.1 - 0.01 15.8 0.3 29 4.8 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.12 OEU20358.1 - 0.015 15.5 0.0 0.8 10.0 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif 2 SET_assoc PF11767.8 OEU20358.1 - 0.16 11.6 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated OTU PF02338.19 OEU20359.1 - 1.7e-17 64.1 0.0 2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3050 PF11251.8 OEU20359.1 - 0.052 13.2 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) TFIIA PF03153.13 OEU20360.1 - 0.67 9.9 35.9 0.021 14.8 13.5 3.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 OEU20361.1 - 0.081 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein zinc_ribbon_6 PF14599.6 OEU20362.1 - 3.8e-23 81.3 5.7 3.8e-23 81.3 5.7 3.3 3 1 1 4 4 4 1 Zinc-ribbon zf-RING_2 PF13639.6 OEU20362.1 - 1.2e-07 31.9 8.2 1.2e-07 31.9 8.2 4.6 2 2 3 5 5 5 1 Ring finger domain zf-C3HC4_4 PF15227.6 OEU20362.1 - 0.021 15.0 10.7 0.021 15.0 10.7 5.0 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OEU20362.1 - 0.035 14.0 4.2 0.035 14.0 4.2 4.6 4 2 0 4 4 4 0 Prokaryotic RING finger family 4 zf-CHY PF05495.12 OEU20362.1 - 0.057 13.9 3.8 0.057 13.9 3.8 4.6 2 1 1 3 3 3 0 CHY zinc finger Fer4_2 PF12797.7 OEU20362.1 - 0.15 12.2 0.4 0.15 12.2 0.4 6.4 7 2 2 9 9 9 0 4Fe-4S binding domain DUF4777 PF16007.5 OEU20364.1 - 0.0098 16.1 0.0 8.1 6.8 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4777) Cut8 PF08559.10 OEU20364.1 - 0.013 15.1 0.4 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein EAP30 PF04157.16 OEU20364.1 - 0.056 12.7 3.0 2 7.6 1.4 2.4 2 1 0 2 2 2 0 EAP30/Vps36 family RasGEF PF00617.19 OEU20364.1 - 0.098 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 RasGEF domain EF-hand_1 PF00036.32 OEU20365.1 - 0.0001 21.6 4.6 0.051 13.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU20365.1 - 0.0037 17.7 2.6 0.071 13.6 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OEU20365.1 - 0.0049 16.7 1.7 0.018 14.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OEU20365.1 - 0.075 12.6 0.3 0.075 12.6 0.3 2.3 2 0 0 2 2 2 0 EF hand Exo_endo_phos PF03372.23 OEU20366.1 - 8.6e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OEU20366.1 - 0.0076 16.1 0.2 0.084 12.7 0.1 2.6 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase HEAT_2 PF13646.6 OEU20367.1 - 5.9e-05 23.4 0.8 0.00051 20.4 0.8 2.8 1 1 0 1 1 1 1 HEAT repeats Phage_int_SAM_1 PF02899.17 OEU20367.1 - 0.066 13.5 4.2 9.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain HEAT PF02985.22 OEU20367.1 - 0.33 11.3 5.3 14 6.3 0.2 4.5 4 0 0 4 4 4 0 HEAT repeat TPR_12 PF13424.6 OEU20368.1 - 9.7e-08 32.2 1.5 0.24 11.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU20368.1 - 0.0038 17.4 1.1 0.017 15.3 0.1 2.6 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OEU20368.1 - 0.0045 16.8 1.2 0.27 11.2 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20368.1 - 0.0046 16.9 0.3 6.2 7.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU20368.1 - 0.0065 17.2 0.0 0.2 12.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU20368.1 - 0.024 15.1 0.0 2.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20368.1 - 0.058 13.6 3.8 1.7 9.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PK_C PF02887.16 OEU20368.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain ABC1 PF03109.16 OEU20369.1 - 2.8e-29 101.7 0.0 4.6e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family OB_NTP_bind PF07717.16 OEU20372.1 - 1.9e-21 76.2 0.0 5.6e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OEU20372.1 - 2e-19 69.9 0.0 2e-19 69.9 0.0 3.2 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OEU20372.1 - 1.6e-14 54.2 0.0 4.6e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU20372.1 - 5.2e-07 29.6 0.0 2e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OEU20372.1 - 1.7e-05 25.1 0.0 8.3e-05 22.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OEU20372.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU20372.1 - 0.0021 18.4 0.0 0.0075 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OEU20372.1 - 0.0037 16.4 0.0 0.0092 15.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 OEU20372.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_7 PF12775.7 OEU20372.1 - 0.043 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 OEU20372.1 - 0.2 11.3 1.4 0.69 9.5 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 OEU20372.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.4 2 1 1 3 3 3 0 ABC transporter Mad3_BUB1_II PF08171.11 OEU20372.1 - 2.7 8.2 7.7 0.32 11.2 2.7 2.1 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 TRM13 PF05206.14 OEU20374.1 - 1.8e-35 122.7 1.0 3e-35 122.0 1.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 OEU20374.1 - 8.5e-08 31.9 4.4 1.8e-07 30.9 4.4 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 OEU20374.1 - 3.2e-05 23.6 6.5 7.8e-05 22.4 6.5 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein Methyltransf_16 PF10294.9 OEU20374.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase CxC6 PF18721.1 OEU20374.1 - 0.24 11.7 6.0 2.9 8.2 6.0 2.9 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases COX3 PF00510.18 OEU20375.1 - 0.014 15.3 0.6 0.026 14.4 0.2 1.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit III Ribosomal_L32e PF01655.18 OEU20376.1 - 1.8e-48 163.4 0.6 2.2e-48 163.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Glyco_transf_15 PF01793.16 OEU20376.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase TPR_12 PF13424.6 OEU20377.1 - 9.2e-49 163.6 7.1 5.4e-11 42.6 0.0 6.2 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 OEU20377.1 - 9.4e-28 95.3 9.2 0.00016 21.5 0.2 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU20377.1 - 4.5e-20 70.1 25.9 0.0065 16.5 0.1 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20377.1 - 4.3e-16 57.7 31.5 0.011 15.8 0.2 9.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 OEU20377.1 - 3.3e-13 48.8 27.5 0.0012 18.6 0.1 8.8 10 0 0 10 10 10 5 Tetratricopeptide repeat SNAP PF14938.6 OEU20377.1 - 2e-12 47.1 7.8 1.8e-05 24.3 1.0 4.6 1 1 2 5 5 5 5 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OEU20377.1 - 4.2e-09 36.5 8.4 0.45 11.3 0.0 8.3 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20377.1 - 3.6e-08 32.9 7.9 0.79 9.9 0.2 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU20377.1 - 6.3e-07 29.7 1.6 35 5.6 0.0 8.6 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU20377.1 - 7.6e-07 29.7 0.7 16 6.2 0.0 6.5 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU20377.1 - 8.8e-07 28.6 0.0 0.0038 16.7 0.1 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 OEU20377.1 - 2.3e-05 24.8 6.7 3.3 8.3 0.0 6.3 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU20377.1 - 3.7e-05 23.8 7.2 1.5 9.4 0.0 7.2 9 0 0 9 9 9 1 Tetratricopeptide repeat Laps PF10169.9 OEU20377.1 - 0.7 10.5 3.3 8.2 7.0 0.3 2.5 2 0 0 2 2 2 0 Learning-associated protein Fer2_3 PF13085.6 OEU20378.1 - 4.2e-31 107.2 0.0 6.8e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OEU20378.1 - 1e-09 38.8 5.9 1e-09 38.8 5.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OEU20378.1 - 3.3e-08 33.8 7.1 3.3e-08 33.8 7.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OEU20378.1 - 1e-07 32.0 4.0 1e-07 32.0 4.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OEU20378.1 - 0.0018 18.2 0.3 0.0018 18.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 OEU20378.1 - 0.0027 17.9 1.2 0.56 10.4 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OEU20378.1 - 0.012 15.7 7.6 0.012 15.7 7.6 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 OEU20378.1 - 0.029 14.9 9.0 0.029 14.9 9.0 2.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain Dodecin PF07311.12 OEU20378.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Dodecin Period_C PF12114.8 OEU20378.1 - 0.22 11.1 1.7 0.39 10.3 1.7 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pyr_redox_2 PF07992.14 OEU20379.1 - 6.6e-60 202.8 3.8 1.4e-59 201.8 3.9 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU20379.1 - 3.4e-31 107.7 0.1 7.8e-31 106.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU20379.1 - 6.4e-21 74.7 5.8 2.8e-17 63.0 0.6 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU20379.1 - 4.8e-17 62.2 1.5 2.4e-16 59.9 1.5 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU20379.1 - 9.4e-08 31.2 1.4 6.5e-05 21.8 0.7 2.4 2 1 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OEU20379.1 - 6.4e-07 29.1 1.5 1.2e-06 28.2 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU20379.1 - 9e-06 25.0 4.7 2.6e-05 23.5 3.4 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OEU20379.1 - 1.7e-05 24.2 0.6 0.00023 20.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OEU20379.1 - 3.4e-05 24.0 2.4 3.4e-05 24.0 2.4 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OEU20379.1 - 0.00012 21.3 1.0 0.00012 21.3 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 OEU20379.1 - 0.001 18.3 0.2 0.03 13.4 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OEU20379.1 - 0.0018 17.6 1.4 1.2 8.3 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OEU20379.1 - 0.003 17.2 2.4 0.003 17.2 2.4 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OEU20379.1 - 0.0033 16.8 2.5 0.68 9.2 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OEU20379.1 - 0.0089 15.9 3.5 0.18 11.7 0.3 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OEU20379.1 - 0.015 15.7 0.2 8 7.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OEU20379.1 - 0.02 13.9 1.5 0.03 13.4 0.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OEU20379.1 - 0.061 13.3 0.9 6.6 6.7 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 OEU20379.1 - 2.8 8.6 5.2 8.7 7.0 0.6 3.6 3 2 1 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 OEU20380.1 - 9.1e-60 202.4 3.7 1.9e-59 201.3 3.9 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU20380.1 - 4.3e-31 107.4 0.1 9.5e-31 106.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU20380.1 - 9.2e-21 74.2 5.8 3.3e-17 62.8 0.6 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU20380.1 - 6.1e-17 61.8 1.4 3.1e-16 59.5 1.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU20380.1 - 1.4e-07 30.6 1.4 7.5e-05 21.6 0.7 2.4 2 1 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OEU20380.1 - 7.8e-07 28.8 1.4 1.4e-06 27.9 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU20380.1 - 1e-05 24.8 4.5 3e-05 23.3 3.4 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OEU20380.1 - 2e-05 24.0 0.9 0.00021 20.6 0.2 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OEU20380.1 - 3.9e-05 23.8 2.4 3.9e-05 23.8 2.4 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OEU20380.1 - 0.00014 21.1 1.0 0.00014 21.1 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 OEU20380.1 - 0.00091 18.5 3.6 0.038 13.1 0.0 3.6 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 OEU20380.1 - 0.0026 17.1 1.8 0.81 8.9 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OEU20380.1 - 0.0029 16.9 1.6 1.4 8.1 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OEU20380.1 - 0.0035 17.0 2.4 0.0035 17.0 2.4 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OEU20380.1 - 0.012 15.5 3.5 0.21 11.4 0.3 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OEU20380.1 - 0.02 15.3 0.3 9.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OEU20380.1 - 0.024 13.7 1.4 0.035 13.2 0.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OEU20380.1 - 0.079 12.9 0.7 7.7 6.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding GATase_3 PF07685.14 OEU20380.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain F420_oxidored PF03807.17 OEU20380.1 - 3.9 8.1 5.1 10 6.8 0.6 3.5 3 2 1 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent Hydantoinase_B PF02538.14 OEU20381.1 - 3.2e-209 695.6 0.3 4.3e-209 695.2 0.3 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OEU20381.1 - 2.9e-99 332.0 0.0 5.3e-99 331.2 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OEU20381.1 - 1.6e-55 187.6 0.2 4.4e-53 179.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Calycin_like PF13944.6 OEU20381.1 - 0.057 13.7 0.7 1.5 9.1 0.3 2.4 2 0 0 2 2 2 0 Calycin-like beta-barrel domain Globin PF00042.22 OEU20382.1 - 1.4e-13 51.3 0.2 2.3e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 Globin NAD_binding_8 PF13450.6 OEU20383.1 - 6e-13 48.8 0.0 1.7e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU20383.1 - 1.8e-11 44.0 0.0 4.2e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OEU20383.1 - 7.3e-08 31.9 1.2 6.4e-05 22.2 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OEU20383.1 - 5.4e-05 22.5 0.2 9.2e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OEU20383.1 - 0.00018 20.3 0.1 0.013 14.2 0.4 2.5 3 0 0 3 3 3 1 HI0933-like protein GDI PF00996.18 OEU20383.1 - 0.00025 19.7 0.1 0.26 9.7 0.1 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor DAO PF01266.24 OEU20383.1 - 0.00068 19.3 0.2 0.015 14.9 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU20383.1 - 0.0011 18.3 0.2 0.03 13.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU20383.1 - 0.0013 18.0 1.1 0.3 10.1 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU20383.1 - 0.0038 16.6 0.4 0.0065 15.9 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OEU20383.1 - 0.064 12.5 0.7 0.18 11.0 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OEU20383.1 - 0.15 11.1 0.3 6.7 5.6 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OEU20383.1 - 0.26 10.5 0.6 0.46 9.7 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain URO-D PF01208.17 OEU20384.1 - 4.9e-92 308.7 0.0 5.5e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) XPC-binding PF09280.11 OEU20384.1 - 0.027 14.2 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 XPC-binding domain PK PF00224.21 OEU20385.1 - 3.6e-119 397.7 1.4 6.7e-119 396.8 1.4 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OEU20385.1 - 3.5e-20 72.4 0.5 9.3e-20 71.0 0.5 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OEU20385.1 - 0.043 13.0 0.1 0.22 10.6 0.0 2.0 1 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Hexapep PF00132.24 OEU20386.1 - 2.5e-11 42.8 11.6 4.4e-06 26.2 4.1 4.9 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OEU20386.1 - 0.00095 18.9 11.2 0.0054 16.5 3.6 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OEU20386.1 - 0.0039 16.2 1.7 0.0054 15.7 1.4 1.3 1 1 0 1 1 1 1 L-fucokinase CBM_25 PF03423.13 OEU20386.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.5 3 0 0 3 3 3 0 Carbohydrate binding domain (family 25) Secretin_N_2 PF07655.13 OEU20386.1 - 1.2 9.7 12.8 0.24 11.9 2.2 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain SET PF00856.28 OEU20387.1 - 6e-06 26.7 0.1 1.6e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 SET domain SapB_2 PF03489.17 OEU20387.1 - 0.12 12.6 0.2 0.98 9.6 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 2 DUF4830 PF16112.5 OEU20387.1 - 0.14 12.7 0.2 6.5 7.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4830) Glyco_hydro_3_C PF01915.22 OEU20388.1 - 6.8e-41 140.5 0.0 1e-40 139.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OEU20388.1 - 1.4e-34 119.9 0.0 2.1e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OEU20388.1 - 1.5e-09 37.8 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 OEU20389.1 - 8.8e-31 107.5 0.0 2.1e-19 70.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OEU20389.1 - 1.7e-30 106.5 5.3 5e-18 65.8 0.3 3.8 3 1 0 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OEU20389.1 - 1.6e-12 47.4 0.1 4.9e-12 45.8 0.1 1.9 1 1 0 1 1 1 1 Fibronectin type III-like domain PSI_PsaE PF02427.17 OEU20390.1 - 5.5e-32 109.2 3.1 6.9e-32 108.9 3.1 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE Ldh_2 PF02615.14 OEU20391.1 - 5e-104 348.0 0.0 6e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PMI_typeI PF01238.21 OEU20392.1 - 4.5e-93 312.4 0.0 6.2e-92 308.7 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I FBPase PF00316.20 OEU20393.1 - 2.9e-33 115.0 0.2 5.1e-33 114.1 0.2 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain ABC_tran PF00005.27 OEU20394.1 - 5.4e-50 169.5 0.0 1.1e-24 87.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OEU20394.1 - 6.9e-24 84.6 65.0 5.8e-15 55.3 20.5 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 OEU20394.1 - 4.1e-19 69.5 2.8 5.2e-10 39.6 0.0 4.6 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OEU20394.1 - 0.00013 22.6 1.8 0.13 12.7 0.1 3.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OEU20394.1 - 0.00025 20.6 0.0 0.044 13.2 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OEU20394.1 - 0.00056 20.1 0.0 0.099 12.9 0.0 3.6 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 OEU20394.1 - 0.0018 18.2 1.0 1.6 8.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OEU20394.1 - 0.0022 18.4 0.0 0.65 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OEU20394.1 - 0.01 16.2 0.0 1.9 8.9 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU20394.1 - 0.024 14.2 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OEU20394.1 - 0.037 13.3 0.0 8.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 OEU20394.1 - 0.1 12.4 0.2 23 4.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 OEU20394.1 - 0.1 12.3 2.8 2 8.2 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 OEU20394.1 - 0.16 11.6 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF3494 PF11999.8 OEU20395.1 - 7.3e-53 179.3 21.2 9e-53 179.0 21.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU20396.1 - 7.2e-53 179.3 20.5 8.7e-53 179.1 20.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU20397.1 - 9.3e-45 152.8 19.3 1.1e-44 152.6 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU20398.1 - 2.7e-51 174.2 18.3 2.7e-51 174.2 18.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF3494 PF11999.8 OEU20399.1 - 5.9e-23 81.6 7.1 9.1e-23 81.0 7.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF809 PF05663.11 OEU20402.1 - 0.02 15.0 0.1 0.02 15.0 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF809) NAD_binding_8 PF13450.6 OEU20404.1 - 2.4e-11 43.7 0.1 7.4e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU20404.1 - 1.6e-08 34.3 0.3 2.4e-08 33.7 0.3 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OEU20404.1 - 4.6e-08 32.6 0.1 5e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU20404.1 - 3.2e-05 22.8 0.1 4.9e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OEU20404.1 - 6.3e-05 22.2 0.4 9.6e-05 21.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OEU20404.1 - 8.9e-05 22.2 0.6 0.00012 21.8 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OEU20404.1 - 0.00014 22.3 0.3 0.00014 22.3 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU20404.1 - 0.00076 18.8 0.4 0.0013 18.0 0.1 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 OEU20404.1 - 0.00091 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU20404.1 - 0.0025 17.1 0.8 0.0041 16.4 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OEU20404.1 - 0.013 14.8 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OEU20404.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OEU20404.1 - 0.017 14.6 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus XdhC_C PF13478.6 OEU20404.1 - 0.025 15.1 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 OEU20404.1 - 0.086 13.1 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1188 PF06690.11 OEU20404.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) RVT_3 PF13456.6 OEU20405.1 - 3.8e-11 42.9 0.1 9.1e-07 28.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase-like zf-C2H2_6 PF13912.6 OEU20405.1 - 6.4e-07 29.2 4.2 0.0004 20.3 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OEU20405.1 - 2.1e-06 28.1 4.9 0.017 15.9 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OEU20405.1 - 1.2e-05 25.5 5.2 0.011 16.1 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type RNase_H PF00075.24 OEU20405.1 - 0.00025 21.3 0.1 0.001 19.3 0.0 1.9 1 1 1 2 2 2 1 RNase H zf_UBZ PF18439.1 OEU20405.1 - 0.00046 19.7 1.2 0.58 9.8 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 OEU20405.1 - 0.0091 16.3 3.7 0.15 12.4 0.1 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 OEU20405.1 - 0.03 14.4 8.3 0.26 11.4 1.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.7 OEU20405.1 - 0.08 13.4 3.6 0.34 11.4 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 OEU20405.1 - 0.11 12.5 3.1 0.26 11.2 3.1 1.7 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 OEU20405.1 - 0.16 12.3 2.1 5 7.5 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OEU20405.1 - 0.22 11.3 2.5 1.3 8.8 0.8 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 OEU20405.1 - 0.24 11.9 4.1 1.5 9.4 0.0 2.8 3 0 0 3 3 2 0 Zinc-finger double domain zf-HYPF PF07503.12 OEU20405.1 - 0.49 10.2 5.4 3.8 7.4 1.1 2.6 2 0 0 2 2 2 0 HypF finger zinc-ribbons_6 PF07191.12 OEU20405.1 - 6.1 6.9 9.9 0.61 10.1 4.1 2.3 2 1 1 3 3 3 0 zinc-ribbons RVT_1 PF00078.27 OEU20406.1 - 7.4e-06 25.6 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU20406.1 - 0.028 15.1 0.7 0.11 13.3 0.7 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DAO PF01266.24 OEU20407.1 - 1.9e-46 159.3 1.7 1.5e-45 156.3 1.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU20407.1 - 1e-09 38.1 0.0 1.6e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU20407.1 - 9e-07 29.4 0.2 3e-06 27.7 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU20407.1 - 1.2e-06 28.6 1.0 3.2e-06 27.3 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OEU20407.1 - 1.8e-06 27.5 0.1 0.004 16.5 0.1 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OEU20407.1 - 2.1e-06 26.7 0.4 0.034 12.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OEU20407.1 - 2.5e-05 23.6 0.9 5.7e-05 22.4 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OEU20407.1 - 6.6e-05 22.9 0.6 0.043 13.8 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OEU20407.1 - 0.00022 20.7 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU20407.1 - 0.00041 19.7 0.0 0.0035 16.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OEU20407.1 - 0.0025 17.0 1.0 0.24 10.4 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OEU20407.1 - 0.0054 15.8 0.5 0.073 12.1 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 OEU20407.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OEU20407.1 - 0.047 12.9 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OEU20407.1 - 0.051 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OEU20407.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-RING_2 PF13639.6 OEU20410.1 - 1e-09 38.6 11.8 2e-08 34.4 5.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 OEU20410.1 - 5.8e-09 36.1 10.2 1.6e-08 34.7 10.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OEU20410.1 - 8.8e-07 28.6 6.0 0.0034 17.1 1.6 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU20410.1 - 1.1e-06 28.3 6.0 1.1e-06 28.3 6.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU20410.1 - 3.1e-06 26.9 8.5 1.1e-05 25.1 8.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU20410.1 - 0.00013 21.9 1.9 0.0003 20.7 1.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU20410.1 - 0.00015 21.7 7.3 0.00017 21.5 5.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU20410.1 - 0.0016 18.5 8.8 0.0048 16.9 8.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPC25 PF06703.11 OEU20410.1 - 0.0046 16.8 0.5 0.044 13.6 0.5 2.2 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Zn_ribbon_17 PF17120.5 OEU20410.1 - 0.006 16.2 6.8 0.015 14.9 6.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OEU20410.1 - 0.021 14.7 3.2 0.021 14.7 3.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OEU20410.1 - 0.027 14.3 3.2 0.057 13.3 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OEU20410.1 - 0.59 10.0 12.3 0.85 9.5 11.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TMEM132D_C PF15706.5 OEU20410.1 - 0.78 9.6 0.0 0.78 9.6 0.0 2.5 4 0 0 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FANCL_C PF11793.8 OEU20410.1 - 1.8 8.8 11.7 2.3 8.4 9.7 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain 2OG-FeII_Oxy PF03171.20 OEU20412.1 - 5.3e-11 42.9 0.0 1.4e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mucin PF01456.17 OEU20412.1 - 4.5 7.3 25.2 2.3 8.2 14.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein PRIMA1 PF16101.5 OEU20413.1 - 0.00013 22.0 5.2 0.0031 17.5 4.6 2.1 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 SNARE PF05739.19 OEU20413.1 - 0.0096 15.9 0.5 0.017 15.1 0.5 1.3 1 0 0 1 1 1 1 SNARE domain OppC_N PF12911.7 OEU20413.1 - 0.072 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Mito_fiss_reg PF05308.11 OEU20413.1 - 0.18 11.9 1.8 0.26 11.4 1.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OEU20413.1 - 0.26 10.8 5.1 0.39 10.1 5.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal YvrJ PF12841.7 OEU20413.1 - 0.46 10.1 3.7 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 YvrJ protein family GHD PF17834.1 OEU20414.1 - 0.0023 18.0 0.1 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase zf-CCHC PF00098.23 OEU20415.1 - 0.0088 16.1 2.9 0.017 15.2 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Totivirus_coat PF05518.11 OEU20415.1 - 0.93 7.5 4.0 1.3 6.9 4.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein Yae1_N PF09811.9 OEU20416.1 - 3.5e-06 26.6 44.2 14 5.4 0.2 13.4 3 3 5 8 8 8 5 Essential protein Yae1, N terminal Ntox25 PF15530.6 OEU20416.1 - 0.046 13.9 1.0 43 4.2 0.0 4.0 1 1 3 4 4 4 0 Bacterial toxin 25 MspA PF09203.11 OEU20416.1 - 0.05 13.5 11.3 2e+03 -1.5 11.3 4.3 1 1 0 1 1 1 0 MspA Rick_17kDa_Anti PF05433.15 OEU20416.1 - 2.7 7.9 47.3 0.55 10.1 1.6 7.1 3 2 4 8 8 8 0 Glycine zipper 2TM domain DUF4567 PF15131.6 OEU20416.1 - 2.9 8.0 24.6 27 4.9 0.1 7.2 1 1 2 6 6 6 0 Domain of unknown function (DUF4567) DDE_Tnp_4 PF13359.6 OEU20419.1 - 0.00053 19.7 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease RE_TdeIII PF09520.10 OEU20419.1 - 0.062 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII HisG_C PF08029.11 OEU20420.1 - 0.072 13.3 0.0 0.47 10.6 0.0 2.3 3 0 0 3 3 3 0 HisG, C-terminal domain FTH PF01827.27 OEU20420.1 - 0.12 12.1 0.5 15 5.3 0.1 2.3 2 0 0 2 2 2 0 FTH domain DSBA PF01323.20 OEU20422.1 - 3.4e-07 30.2 1.9 0.0023 17.8 0.4 2.2 1 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 OEU20422.1 - 0.00099 19.1 0.0 0.78 9.8 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_4 PF13462.6 OEU20422.1 - 0.0026 18.0 0.3 0.003 17.7 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU20422.1 - 0.0043 17.5 0.7 0.019 15.4 0.7 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Patched PF02460.18 OEU20422.1 - 0.082 11.0 0.3 0.088 10.9 0.3 1.0 1 0 0 1 1 1 0 Patched family HypF_C PF17788.1 OEU20422.1 - 0.13 13.0 0.2 5.9 7.6 0.0 2.2 1 1 1 2 2 2 0 HypF Kae1-like domain TNFR_16_TM PF18422.1 OEU20423.1 - 0.54 10.3 4.5 1.8 8.6 0.2 2.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain ClpS PF02617.17 OEU20424.1 - 1.3e-13 50.6 1.5 1.4e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS DUF3671 PF12420.8 OEU20425.1 - 0.0025 17.9 0.9 0.28 11.3 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function DUF3500 PF12006.8 OEU20426.1 - 0.089 12.3 7.0 0.1 12.1 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF2407_C PF13373.6 OEU20426.1 - 6 7.0 11.3 11 6.2 0.1 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Retrotran_gag_2 PF14223.6 OEU20428.1 - 0.0038 16.9 3.1 0.012 15.3 0.1 2.5 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type MnmE_helical PF12631.7 OEU20428.1 - 0.025 14.7 1.7 0.043 14.0 1.7 1.3 1 0 0 1 1 1 0 MnmE helical domain DUF4407 PF14362.6 OEU20428.1 - 1.6 8.0 5.9 2.4 7.4 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ig_5 PF16681.5 OEU20429.1 - 0.054 13.9 0.1 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PDZ PF00595.24 OEU20430.1 - 1.6e-08 34.8 0.0 4.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU20430.1 - 7.4e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU20430.1 - 0.018 15.4 0.0 0.058 13.7 0.0 1.9 1 0 0 1 1 1 0 PDZ domain DUF413 PF04219.12 OEU20430.1 - 0.074 13.1 0.3 0.87 9.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF ApbA PF02558.16 OEU20431.1 - 1.2e-20 73.6 0.0 2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OEU20431.1 - 1.9e-18 66.9 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MTTB PF06253.11 OEU20431.1 - 0.048 11.6 0.0 0.073 11.0 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Aminotran_5 PF00266.19 OEU20432.1 - 1.5e-144 481.5 0.1 1.7e-144 481.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OEU20432.1 - 1.2e-07 31.4 0.6 1.2e-05 24.9 0.3 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OEU20432.1 - 2.2e-07 30.4 0.2 3.2e-07 29.9 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 OEU20432.1 - 2.8e-05 22.8 0.0 4.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.20 OEU20432.1 - 3.8e-05 22.4 0.3 6.4e-05 21.7 0.3 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aldolase PF01081.19 OEU20433.1 - 6.1e-32 110.6 0.0 7.7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 KDPG and KHG aldolase RraA-like PF03737.15 OEU20434.1 - 1e-28 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA DUF4336 PF14234.6 OEU20435.1 - 1.3e-17 64.0 0.0 7.7e-16 58.2 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) PMC2NT PF08066.12 OEU20436.1 - 0.085 13.6 1.4 0.3 11.8 1.4 1.9 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Flavodoxin_1 PF00258.25 OEU20437.1 - 2.9e-22 79.4 0.9 3.3e-22 79.2 0.9 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 OEU20437.1 - 0.00019 21.7 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain FMN_red PF03358.15 OEU20437.1 - 0.0011 18.7 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_3 PF12641.7 OEU20437.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin domain PABP PF00658.18 OEU20439.1 - 0.28 11.4 3.4 1.4 9.1 0.8 2.8 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain MRP-S32 PF10210.9 OEU20439.1 - 2.1 9.0 9.2 0.27 11.8 2.2 3.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 DUF1658 PF07871.11 OEU20440.1 - 3.2 7.8 6.8 17 5.6 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Ribosomal_L1 PF00687.21 OEU20441.1 - 6.2e-43 146.9 0.9 7.9e-43 146.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family YchF-GTPase_C PF06071.13 OEU20442.1 - 1.1e-40 137.7 0.4 2.8e-40 136.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OEU20442.1 - 4.6e-25 87.9 0.1 2.5e-24 85.6 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU20442.1 - 6.9e-09 35.4 0.8 9.5e-08 31.7 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU20442.1 - 0.021 14.9 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 OEU20442.1 - 0.038 13.9 0.1 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OEU20442.1 - 0.15 12.3 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.24 OEU20443.1 - 5.8e-156 519.9 9.7 6.7e-156 519.7 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 OEU20443.1 - 0.027 14.3 0.8 0.11 12.3 0.4 2.1 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF3730 PF12530.8 OEU20444.1 - 0.022 14.3 0.3 0.59 9.7 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Phage-scaffold PF09306.10 OEU20444.1 - 0.025 14.0 1.0 0.041 13.2 1.0 1.2 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Tti2 PF10521.9 OEU20444.1 - 0.026 14.1 0.5 0.14 11.7 0.1 2.5 3 0 0 3 3 3 0 Tti2 family tRNA_int_endo PF01974.17 OEU20445.1 - 1.1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Mrr_cat PF04471.12 OEU20445.1 - 0.024 14.7 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Fungal_lectin_2 PF18647.1 OEU20445.1 - 0.089 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin zf-CCCH_4 PF18044.1 OEU20446.1 - 0.00068 19.4 1.5 0.001 18.8 1.5 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OEU20446.1 - 0.0082 16.0 1.6 0.014 15.3 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU20446.1 - 0.0095 16.0 1.4 0.017 15.2 1.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 OEU20446.1 - 0.14 12.7 2.6 0.36 11.4 2.6 1.7 1 1 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Sec3_C PF09763.9 OEU20447.1 - 4.6e-24 84.8 2.6 5.7e-15 54.8 0.1 2.8 1 1 1 2 2 2 2 Exocyst complex component Sec3 MRG PF05712.13 OEU20449.1 - 8e-27 93.8 1.9 1e-26 93.5 1.9 1.1 1 0 0 1 1 1 1 MRG DUF3437 PF11919.8 OEU20449.1 - 0.14 12.0 0.3 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) AF-4 PF05110.13 OEU20451.1 - 0.12 10.4 4.4 0.17 9.9 4.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GHMP_kinases_C PF08544.13 OEU20452.1 - 8.2e-06 26.1 0.0 9.6e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OEU20452.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain Img2 PF05046.14 OEU20454.1 - 2.5e-20 72.6 0.6 1.2e-19 70.4 0.1 2.2 2 1 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) Blt1 PF12754.7 OEU20454.1 - 0.041 14.2 0.4 0.071 13.4 0.4 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF2968 PF11180.8 OEU20455.1 - 0.027 14.1 0.9 0.027 14.1 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) UPF0242 PF06785.11 OEU20455.1 - 0.15 12.1 7.9 0.55 10.3 4.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 OEU20455.1 - 0.17 12.5 5.6 0.065 13.9 1.3 2.5 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 OEU20455.1 - 0.34 11.0 9.9 0.052 13.7 4.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor Mto2_bdg PF12808.7 OEU20455.1 - 0.59 10.5 8.2 0.23 11.8 1.7 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SHE3 PF17078.5 OEU20455.1 - 1.6 8.4 9.6 0.82 9.3 3.4 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 MBD_C PF14048.6 OEU20455.1 - 1.9 9.3 6.9 0.6 10.8 0.2 3.3 3 0 0 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Spc7 PF08317.11 OEU20455.1 - 3.1 6.6 10.3 1.4 7.7 5.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Pyr_redox_3 PF13738.6 OEU20456.1 - 0.099 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 OEU20457.1 - 2.8e-16 60.8 0.0 5.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OEU20457.1 - 6.3e-15 55.3 0.1 1.2e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU20457.1 - 6.3e-07 29.2 0.4 1.3e-06 28.2 0.0 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OEU20457.1 - 0.032 14.1 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase IMS PF00817.20 OEU20457.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 impB/mucB/samB family Tim44 PF04280.15 OEU20458.1 - 3.2e-24 85.7 0.0 6.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain Mpv17_PMP22 PF04117.12 OEU20459.1 - 0.00036 20.7 0.5 0.00036 20.7 0.5 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Baculo_PEP_C PF04513.12 OEU20460.1 - 0.064 13.3 1.3 0.13 12.3 1.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YojJ PF10372.9 OEU20460.1 - 0.17 12.0 1.8 0.3 11.2 1.3 1.7 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus RVT_2 PF07727.14 OEU20461.1 - 1.3e-09 38.1 0.4 2.7e-09 37.0 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DPRP PF04244.13 OEU20461.1 - 0.0011 18.9 0.0 0.083 12.7 0.0 2.3 2 0 0 2 2 2 2 Deoxyribodipyrimidine photo-lyase-related protein rve PF00665.26 OEU20461.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-RING_2 PF13639.6 OEU20463.1 - 9.4e-09 35.5 16.3 1.4e-08 34.9 16.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OEU20463.1 - 5e-06 26.7 10.9 9.1e-06 25.9 10.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU20463.1 - 1.3e-05 24.9 14.8 2.1e-05 24.3 14.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU20463.1 - 1.6e-05 24.6 13.4 2.6e-05 24.0 13.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU20463.1 - 1.9e-05 24.4 16.5 3e-05 23.8 16.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU20463.1 - 0.0047 16.8 12.4 0.0091 15.8 12.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OEU20463.1 - 0.0069 16.3 14.9 0.011 15.7 14.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU20463.1 - 0.012 15.7 11.2 0.021 14.8 11.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 OEU20463.1 - 0.021 14.5 12.7 0.036 13.8 12.7 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 OEU20463.1 - 0.056 13.5 4.7 0.098 12.7 4.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OEU20463.1 - 1.5 9.0 13.4 3.5 7.9 13.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DNA_pol_B PF00136.21 OEU20464.1 - 1.5e-136 455.7 0.2 2.1e-136 455.3 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OEU20464.1 - 7.4e-73 245.6 0.0 1.2e-72 244.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OEU20464.1 - 1.1e-07 32.2 5.1 3.1e-07 30.8 5.1 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 OEU20464.1 - 5.6e-05 22.2 1.0 0.00083 18.3 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 OEU20464.1 - 0.031 14.0 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 3'-5' exonuclease TCR PF03638.15 OEU20465.1 - 6.1e-19 68.1 44.4 1.8e-09 37.7 12.6 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain preSET_CXC PF18264.1 OEU20465.1 - 5.8 7.5 37.6 5 7.7 7.9 2.6 2 1 0 2 2 2 0 CXC domain TMEM234 PF10639.9 OEU20466.1 - 2.4e-24 85.6 2.5 4.1e-23 81.6 2.5 2.0 1 1 0 1 1 1 1 Putative transmembrane family 234 DUF3446 PF11928.8 OEU20466.1 - 0.033 14.5 10.3 0.033 14.5 10.3 1.6 2 0 0 2 2 2 0 Early growth response N-terminal domain TSP9 PF11493.8 OEU20466.1 - 0.046 14.4 0.6 0.07 13.8 0.6 1.2 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Closter_coat PF01785.17 OEU20466.1 - 0.24 10.7 1.1 0.33 10.2 1.1 1.2 1 0 0 1 1 1 0 Closterovirus coat protein DUF3558 PF12079.8 OEU20466.1 - 1.1 9.3 4.8 1.3 9.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) IMUP PF15761.5 OEU20466.1 - 1.1 10.0 11.3 1.6 9.4 11.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 OEU20466.1 - 3.6 7.1 19.5 4.5 6.8 19.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 OEU20466.1 - 5.1 6.9 5.3 6.8 6.5 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Syntaphilin PF15290.6 OEU20466.1 - 8.4 5.9 10.7 11 5.6 10.7 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp NifU_N PF01592.16 OEU20467.1 - 2.3e-53 179.7 0.2 2.9e-53 179.4 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain HORMA PF02301.18 OEU20468.1 - 8.4e-25 87.6 0.0 1e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Peptidase_M16 PF00675.20 OEU20469.1 - 4.3e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF4797 PF16051.5 OEU20469.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) MAAL_N PF05034.13 OEU20469.1 - 0.067 12.8 0.5 0.29 10.8 0.1 2.1 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus IKI3 PF04762.12 OEU20470.1 - 2.2e-155 519.1 0.0 6.1e-94 315.8 0.0 2.1 1 1 1 2 2 2 2 IKI3 family RimM PF01782.18 OEU20471.1 - 1.5e-12 47.5 0.0 2.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 OEU20471.1 - 0.0011 19.0 1.5 0.089 12.9 0.5 2.8 3 0 0 3 3 3 2 PRC-barrel domain ANAPC4_WD40 PF12894.7 OEU20472.1 - 2.8e-08 33.9 0.0 0.076 13.3 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OEU20472.1 - 0.00079 20.2 3.4 4.7 8.2 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 OEU20472.1 - 0.0031 16.9 1.3 0.52 9.6 0.1 2.9 2 1 1 3 3 3 2 WD40-like domain TPP_enzyme_N PF02776.18 OEU20473.1 - 1e-34 119.6 0.0 2.1e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OEU20473.1 - 7e-34 116.8 0.0 1.2e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OEU20473.1 - 2.9e-33 114.5 0.0 1.2e-32 112.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 OEU20473.1 - 0.026 14.3 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DXP_synthase_N PF13292.6 OEU20473.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase IGPS PF00218.21 OEU20474.1 - 0.063 12.4 0.1 0.072 12.2 0.1 1.1 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase RRM_1 PF00076.22 OEU20475.1 - 5.5e-15 54.9 0.0 2.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M16C_assoc PF08367.11 OEU20476.1 - 2e-59 200.8 1.0 3.3e-59 200.1 1.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OEU20476.1 - 1.3e-26 93.7 0.0 6.9e-23 81.6 0.0 4.1 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OEU20476.1 - 5.3e-07 29.7 0.0 2.5e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2670 PF10875.8 OEU20478.1 - 0.18 11.9 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) Ndc1_Nup PF09531.10 OEU20478.1 - 1.5 7.4 9.0 3.1 6.4 9.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HTH_9 PF08221.11 OEU20480.1 - 5.4e-11 42.4 3.4 0.0058 16.7 0.0 4.5 4 0 0 4 4 4 4 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 OEU20480.1 - 1.5e-05 24.8 0.0 0.00037 20.3 0.0 2.8 2 0 0 2 2 2 1 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.13 OEU20480.1 - 0.017 14.9 7.7 0.45 10.2 3.2 3.1 2 1 1 3 3 3 0 RNA polymerase III subunit RPC82 Rrf2 PF02082.20 OEU20480.1 - 0.11 12.9 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator Cons_hypoth95 PF03602.15 OEU20480.1 - 0.12 12.1 0.7 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 WW PF00397.26 OEU20481.1 - 7.6e-07 29.1 5.1 1.8e-06 27.9 5.1 1.7 1 0 0 1 1 1 1 WW domain VWA_2 PF13519.6 OEU20481.1 - 0.017 15.8 0.2 0.37 11.5 0.1 2.9 2 1 0 2 2 2 0 von Willebrand factor type A domain ECH_1 PF00378.20 OEU20484.1 - 3.1e-41 141.3 0.0 8.4e-41 139.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU20484.1 - 3e-24 86.2 0.0 5.5e-24 85.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Lactamase_B_2 PF12706.7 OEU20485.1 - 6.2e-14 52.0 0.5 1.8e-13 50.5 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OEU20485.1 - 4e-08 33.5 0.0 0.00057 20.0 0.1 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OEU20485.1 - 0.00028 20.5 0.0 0.00085 19.0 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease CLU PF13236.6 OEU20486.1 - 1.1e-64 218.3 0.0 4e-64 216.5 0.0 2.0 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 OEU20486.1 - 1.5e-34 119.5 0.0 1.5e-34 119.5 0.0 3.1 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OEU20486.1 - 5.2e-15 55.5 5.0 3.7e-09 36.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CLU_N PF15044.6 OEU20486.1 - 2.9e-05 24.4 0.1 0.44 10.9 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 OEU20486.1 - 0.00012 21.7 4.9 0.0011 18.7 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20486.1 - 0.00045 20.2 2.8 0.00099 19.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU20486.1 - 0.00098 18.9 0.1 5.4 7.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU20486.1 - 0.0025 17.8 10.3 0.027 14.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF236 PF03057.14 OEU20486.1 - 0.12 12.4 0.1 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 DUF236 repeat PTPA PF03095.15 OEU20487.1 - 2.7e-57 194.5 0.0 3.4e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF3638 PF12340.8 OEU20488.1 - 1e-24 87.1 0.1 4.7e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) EF-hand_1 PF00036.32 OEU20488.1 - 7.1e-16 56.5 3.1 0.00016 21.0 0.6 4.0 3 0 0 3 3 3 3 EF hand DUF3645 PF12359.8 OEU20488.1 - 4e-12 45.3 0.0 9.2e-12 44.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 OEU20488.1 - 1.8e-11 44.3 14.0 3.6e-08 33.7 0.4 3.1 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU20488.1 - 3.1e-11 42.2 4.6 0.017 14.6 0.0 4.0 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OEU20488.1 - 5.1e-11 41.6 5.4 0.014 15.3 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain Vps62 PF06101.11 OEU20488.1 - 6.2e-05 21.5 0.0 0.00013 20.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 SH3_9 PF14604.6 OEU20488.1 - 0.00028 20.7 0.0 0.00064 19.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OEU20488.1 - 0.00076 19.0 0.2 0.0019 17.8 0.2 1.8 1 0 0 1 1 1 1 SH3 domain EF-hand_8 PF13833.6 OEU20488.1 - 0.0011 18.7 2.7 3.2 7.7 0.3 3.7 3 0 0 3 3 3 2 EF-hand domain pair SH3_2 PF07653.17 OEU20488.1 - 0.0017 18.0 0.1 0.0049 16.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain ResIII PF04851.15 OEU20488.1 - 0.019 15.0 2.7 0.03 14.3 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Peptidase_M22 PF00814.25 OEU20489.1 - 4.8e-86 288.8 0.0 5.5e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OEU20489.1 - 0.00028 20.7 0.0 0.0012 18.6 0.0 1.8 1 1 0 2 2 2 1 Carbamoyltransferase N-terminus BcrAD_BadFG PF01869.20 OEU20489.1 - 0.077 12.5 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NRD1_2 PF01995.16 OEU20489.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 DnaJ PF00226.31 OEU20490.1 - 5.2e-16 58.5 2.1 1.2e-15 57.3 2.1 1.6 1 1 0 1 1 1 1 DnaJ domain DUF4392 PF14336.6 OEU20491.1 - 3.8e-75 253.1 0.0 4.3e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) SR-25 PF10500.9 OEU20492.1 - 0.064 12.9 20.7 0.071 12.7 20.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 OEU20492.1 - 0.16 11.7 25.5 0.19 11.5 25.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 OEU20492.1 - 4.6 5.7 17.1 5.5 5.4 17.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2228 PF10228.9 OEU20492.1 - 6.1 6.5 12.4 6.6 6.4 12.4 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Noggin PF05806.12 OEU20492.1 - 6.8 6.5 8.3 7.6 6.4 8.3 1.1 1 0 0 1 1 1 0 Noggin DUF2358 PF10184.9 OEU20493.1 - 0.00012 22.3 0.3 0.00029 21.1 0.3 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 OEU20493.1 - 0.14 12.9 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain UQ_con PF00179.26 OEU20494.1 - 4.5e-47 159.2 0.0 5.8e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU20494.1 - 7.3e-07 29.0 0.0 4.8e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B UBA PF00627.31 OEU20494.1 - 3e-06 27.0 0.2 5.1e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain RWD PF05773.22 OEU20494.1 - 0.0027 18.0 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 OEU20494.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain UBA_2 PF08587.11 OEU20494.1 - 0.14 12.3 0.5 0.35 11.0 0.5 1.7 1 1 0 1 1 1 0 Ubiquitin associated domain (UBA) zf-RING_2 PF13639.6 OEU20495.1 - 2.3e-12 47.0 13.4 4.7e-12 46.1 13.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU20495.1 - 6.7e-07 28.9 8.2 1.3e-06 28.1 8.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OEU20495.1 - 2.3e-06 27.8 12.7 6e-06 26.4 12.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU20495.1 - 3.9e-06 26.6 13.3 3.9e-06 26.6 13.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU20495.1 - 0.0009 19.1 13.0 0.0017 18.2 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU20495.1 - 0.0016 18.3 12.2 0.0016 18.3 12.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU20495.1 - 0.003 17.5 12.2 0.006 16.5 12.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU20495.1 - 0.0077 16.1 9.5 0.015 15.1 9.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OEU20495.1 - 0.018 15.1 8.4 0.075 13.1 8.5 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OEU20495.1 - 0.025 14.6 11.0 0.025 14.6 11.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger OrfA PF17495.2 OEU20495.1 - 0.12 12.6 0.2 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 Vpr-like OrfA Zn_ribbon_17 PF17120.5 OEU20495.1 - 0.74 9.5 10.9 1.6 8.4 10.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Cyt-b5 PF00173.28 OEU20496.1 - 1.5e-10 41.1 0.2 2.7e-09 37.1 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF4419 PF14388.6 OEU20496.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) DUF1685 PF07939.11 OEU20496.1 - 0.047 13.5 0.5 0.13 12.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Sugar_tr PF00083.24 OEU20497.1 - 8.8e-93 311.6 21.9 1.1e-92 311.2 21.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU20497.1 - 5.1e-28 98.0 36.6 4.6e-19 68.6 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SNF2_N PF00176.23 OEU20498.1 - 6.9e-19 67.8 1.9 4.5e-18 65.1 1.8 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU20498.1 - 6.4e-09 36.2 0.0 1.8e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 OEU20499.1 - 3.6e-06 26.7 0.0 0.00042 20.1 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OEU20499.1 - 0.043 13.7 0.0 9.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif SepSecS PF05889.13 OEU20500.1 - 2.5e-111 372.1 0.0 3.3e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 OEU20500.1 - 3.6e-06 26.5 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OEU20500.1 - 0.02 14.1 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF442 PF04273.13 OEU20500.1 - 0.024 14.7 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative phosphatase (DUF442) K_channel_TID PF07941.11 OEU20501.1 - 0.71 10.4 10.8 0.25 11.8 7.7 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-CW PF07496.15 OEU20502.1 - 5.2e-11 42.4 7.3 2.2e-10 40.4 7.3 2.2 1 0 0 1 1 1 1 CW-type Zinc Finger SET PF00856.28 OEU20502.1 - 2.5e-06 28.0 0.0 2.5e-06 28.0 0.0 5.6 7 2 0 7 7 7 1 SET domain hnRNP_Q_AcD PF18360.1 OEU20504.1 - 0.019 14.9 0.8 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain MoCF_biosynth PF00994.24 OEU20505.1 - 2.3e-21 76.0 0.1 3.4e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.17 OEU20505.1 - 4.2e-16 59.1 0.0 6.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) DUF3421 PF11901.8 OEU20505.1 - 0.016 15.2 0.1 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) DUF1576 PF07613.11 OEU20507.1 - 0.032 13.7 1.3 0.044 13.3 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1576) DUF4148 PF13663.6 OEU20507.1 - 3.2 8.0 9.8 2 8.7 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Glycolytic PF00274.19 OEU20508.1 - 2.1e-105 352.3 0.0 2.5e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SpoU_methylase PF00588.19 OEU20509.1 - 1.2e-15 57.9 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family HOIP-UBA PF16678.5 OEU20511.1 - 0.028 14.4 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair Kinesin PF00225.23 OEU20512.1 - 2.8e-91 305.9 0.0 3.1e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU20512.1 - 2.5e-14 53.5 0.0 4.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HA PF03457.14 OEU20513.1 - 1.2e-50 169.6 17.0 1.3e-19 70.3 0.1 4.3 5 0 0 5 5 5 4 Helicase associated domain TrmO PF01980.16 OEU20513.1 - 0.16 12.2 0.0 1.8 8.8 0.0 2.1 1 1 1 2 2 2 0 tRNA-methyltransferase O HMG_box PF00505.19 OEU20514.1 - 5.4e-33 113.2 11.5 5.4e-20 71.6 2.9 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box Rtt106 PF08512.12 OEU20514.1 - 9.6e-27 93.2 0.0 8.3e-26 90.2 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box_2 PF09011.10 OEU20514.1 - 3e-24 85.4 18.7 1.3e-16 60.9 2.0 3.0 3 0 0 3 3 3 2 HMG-box domain SSrecog PF03531.14 OEU20514.1 - 8.8e-15 54.4 0.0 7.7e-14 51.4 0.0 2.6 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 OEU20514.1 - 1.3e-09 38.4 0.0 2.7e-07 30.9 0.0 2.8 2 1 0 2 2 2 1 POB3-like N-terminal PH domain CHDNT PF08073.12 OEU20514.1 - 8e-09 35.3 0.1 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 2 CHDNT (NUC034) domain Ccdc124 PF06244.12 OEU20514.1 - 0.013 16.1 13.3 0.62 10.6 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 LIN37 PF15306.6 OEU20514.1 - 0.43 10.8 6.7 24 5.1 4.0 3.2 3 0 0 3 3 3 0 LIN37 PAP_fibrillin PF04755.12 OEU20515.1 - 6e-17 62.2 0.4 9.8e-16 58.3 0.4 2.1 1 1 0 1 1 1 1 PAP_fibrillin GTP_EFTU PF00009.27 OEU20516.1 - 9.9e-30 103.5 5.6 9.9e-30 103.5 5.6 3.1 3 1 0 3 3 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OEU20516.1 - 1.2e-22 80.0 0.7 3.2e-22 78.6 0.7 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OEU20516.1 - 1.2e-12 47.9 0.8 5.9e-12 45.7 0.2 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OEU20516.1 - 3.3e-07 30.6 1.7 2.7e-05 24.5 0.1 3.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OEU20516.1 - 3.3e-07 30.3 4.6 4.7e-05 23.4 0.2 3.7 2 1 1 3 3 3 1 RsgA GTPase IF2_N PF04760.15 OEU20516.1 - 5e-07 29.4 0.0 1.7e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 OEU20516.1 - 1.3e-06 28.0 0.1 5.4e-06 26.0 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OEU20516.1 - 2.7e-06 27.0 1.1 2.7e-06 27.0 1.1 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.22 OEU20516.1 - 5e-05 23.0 0.1 9.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OEU20516.1 - 9.1e-05 22.0 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 OEU20516.1 - 0.0045 17.0 0.1 2.9 7.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Voldacs PF03517.13 OEU20516.1 - 0.0066 16.6 0.4 2.6 8.2 0.2 2.4 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling ATP_bind_1 PF03029.17 OEU20516.1 - 0.0085 15.9 0.0 0.03 14.1 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 OEU20516.1 - 0.013 15.5 0.6 0.047 13.7 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 OEU20516.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OEU20516.1 - 0.038 13.3 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 AIG1 family PduV-EutP PF10662.9 OEU20516.1 - 0.045 13.5 0.3 0.14 11.9 0.3 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 OEU20516.1 - 0.13 12.1 0.1 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_pol_phi PF04931.13 OEU20516.1 - 1.7 6.7 5.5 2.5 6.1 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Aa_trans PF01490.18 OEU20517.1 - 4.3e-47 160.7 27.2 5e-47 160.5 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GAD-like PF08887.11 OEU20517.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain DUF4271 PF14093.6 OEU20517.1 - 0.34 10.8 19.2 0.022 14.7 6.9 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4271) Atx10homo_assoc PF09759.9 OEU20518.1 - 3.4e-06 27.0 0.0 0.0055 16.7 0.0 3.1 1 1 2 3 3 3 3 Spinocerebellar ataxia type 10 protein domain ArfGap PF01412.18 OEU20519.1 - 3e-17 62.8 3.7 3e-17 62.8 3.7 3.6 3 1 0 4 4 4 1 Putative GTPase activating protein for Arf HSP70 PF00012.20 OEU20521.1 - 5.6e-254 843.9 14.1 6.3e-254 843.7 14.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OEU20521.1 - 8.2e-18 64.3 1.7 9.9e-17 60.7 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OEU20521.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4624 PF15417.6 OEU20521.1 - 0.0022 17.8 0.2 0.14 11.9 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4624) FtsA PF14450.6 OEU20521.1 - 0.019 15.4 5.1 1.8 9.0 2.0 3.6 2 1 0 2 2 2 0 Cell division protein FtsA Hydantoinase_A PF01968.18 OEU20521.1 - 0.019 14.2 3.1 0.023 14.0 0.6 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Pex19 PF04614.12 OEU20521.1 - 1.7 8.4 11.1 0.32 10.8 4.2 2.3 2 0 0 2 2 2 0 Pex19 protein family SelP_N PF04592.14 OEU20522.1 - 0.2 11.0 3.0 0.35 10.2 3.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aldo_ket_red PF00248.21 OEU20523.1 - 2.3e-16 59.9 0.0 1.3e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 OEU20524.1 - 4.4e-75 252.4 0.0 5e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20524.1 - 7e-34 117.3 0.0 8.1e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU20524.1 - 9.2e-08 31.7 0.1 1.3e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OEU20524.1 - 4.8e-06 26.1 0.0 1.3e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OEU20524.1 - 0.0012 18.5 0.2 0.0018 17.9 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OEU20524.1 - 0.0014 18.6 0.0 0.12 12.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU20524.1 - 0.0027 16.6 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RAMP4 PF06624.12 OEU20524.1 - 0.063 13.4 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 ALG3 PF05208.13 OEU20525.1 - 8e-117 390.7 22.1 1.4e-116 389.9 22.1 1.4 1 1 0 1 1 1 1 ALG3 protein Pkinase PF00069.25 OEU20526.1 - 9.1e-68 228.5 0.0 1.1e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20526.1 - 3.3e-30 105.2 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU20526.1 - 6.5e-05 23.0 0.0 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU20526.1 - 0.017 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU20526.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PhyH PF05721.13 OEU20528.1 - 1.2e-18 68.1 0.0 2.8e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) QRPTase_C PF01729.19 OEU20529.1 - 6.8e-56 188.7 0.0 8.8e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OEU20529.1 - 6.5e-14 51.7 0.1 9.5e-13 48.0 0.1 2.4 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Voltage_CLC PF00654.20 OEU20530.1 - 1.9e-36 126.1 30.7 7.9e-24 84.5 5.9 3.2 2 1 1 3 3 3 3 Voltage gated chloride channel GPI2 PF06432.11 OEU20531.1 - 1.9e-36 125.9 4.6 2.7e-36 125.5 4.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase ERGIC_N PF13850.6 OEU20531.1 - 0.014 15.7 0.1 0.085 13.2 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1622 PF07784.11 OEU20531.1 - 0.036 14.0 0.6 0.091 12.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) NOA36 PF06524.12 OEU20531.1 - 1.2 8.4 2.8 1.5 8.0 2.8 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 OEU20532.1 - 0.00027 20.0 2.4 0.00035 19.6 2.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU20532.1 - 0.029 13.3 7.6 0.096 11.5 7.5 1.7 1 1 1 2 2 2 0 Sugar (and other) transporter Glyco_transf_64 PF09258.10 OEU20533.1 - 5.4e-51 173.2 0.2 6.1e-51 173.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain ZirS_C PF16583.5 OEU20533.1 - 0.0033 17.0 0.0 0.0069 16.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-regulated secreted antivirulence protein C-terminal domain His_Phos_1 PF00300.22 OEU20534.1 - 3.6e-13 49.6 0.0 4.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Med10 PF09748.9 OEU20535.1 - 9.8e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 1 1 2 2 2 1 Transcription factor subunit Med10 of Mediator complex SecE PF00584.20 OEU20536.1 - 0.0095 15.8 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex EF-hand_2 PF09068.11 OEU20536.1 - 0.0099 16.0 0.3 0.016 15.4 0.3 1.3 1 0 0 1 1 1 1 EF hand Synaphin PF05835.12 OEU20536.1 - 0.21 11.9 1.9 2.3 8.5 0.2 2.2 2 0 0 2 2 2 0 Synaphin protein HAD_2 PF13419.6 OEU20537.1 - 1.2e-10 41.8 0.0 1.2e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU20537.1 - 2.2e-10 41.2 0.0 2.8e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU20537.1 - 4.5e-06 26.6 0.0 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OEU20537.1 - 0.026 14.9 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.22 OEU20538.1 - 4.1e-05 23.4 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HERV-K_env_2 PF13804.6 OEU20538.1 - 0.075 12.8 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein EamA PF00892.20 OEU20539.1 - 1.9e-12 47.5 26.1 3.6e-09 36.9 10.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU20539.1 - 9.5e-09 35.0 4.8 1.4e-08 34.4 4.8 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family DAGAT PF03982.13 OEU20540.1 - 1.5e-30 106.2 0.0 2.1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 OEU20540.1 - 0.01 15.4 0.0 0.027 14.1 0.0 1.7 1 1 0 1 1 1 0 Acyltransferase tRNA_anti-codon PF01336.25 OEU20541.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PAC4 PF16093.5 OEU20542.1 - 5.8e-11 42.4 8.6 7.9e-10 38.8 8.6 2.1 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 NOG1_N PF17835.1 OEU20543.1 - 3.7e-50 170.0 0.2 3.7e-50 170.0 0.2 2.1 2 1 1 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 OEU20543.1 - 5.7e-26 90.1 0.2 1.2e-25 89.0 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 OEU20543.1 - 5.7e-24 83.8 0.8 1.3e-23 82.7 0.8 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 OEU20543.1 - 1.2e-16 60.8 0.0 3.4e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU20543.1 - 2.9e-10 39.9 0.0 6.2e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 OEU20543.1 - 0.003 16.9 0.0 0.0065 15.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 OEU20543.1 - 0.027 14.4 3.9 0.85 9.5 0.0 3.2 3 1 0 3 3 3 0 RsgA GTPase SRPRB PF09439.10 OEU20543.1 - 0.027 13.9 0.0 0.066 12.6 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OEU20543.1 - 0.057 13.6 0.0 0.46 10.7 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PRAP PF15314.6 OEU20543.1 - 0.24 11.9 2.9 0.84 10.2 2.9 1.9 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Dynamin_N PF00350.23 OEU20543.1 - 1.7 8.7 4.0 12 5.9 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Myb_DNA-binding PF00249.31 OEU20545.1 - 1.7e-13 50.5 0.2 2.1e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU20545.1 - 6.7e-05 23.1 0.0 7.6e-05 22.9 0.0 1.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU20545.1 - 0.0019 18.0 0.1 0.0023 17.8 0.1 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Sulfotransfer_2 PF03567.14 OEU20546.1 - 1.7e-08 34.7 2.8 2.8e-08 34.0 2.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family PIP5K PF01504.18 OEU20547.1 - 4.5e-74 249.1 4.8 2.7e-73 246.6 4.8 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kelch_1 PF01344.25 OEU20548.1 - 1.2e-40 136.9 9.3 6.3e-07 28.9 0.0 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 OEU20548.1 - 8.6e-33 112.0 14.3 5.5e-11 42.5 0.2 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OEU20548.1 - 1.9e-31 106.8 10.7 5.6e-06 26.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OEU20548.1 - 5.8e-31 106.2 15.5 3.1e-07 30.3 0.5 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OEU20548.1 - 2.5e-29 100.5 17.3 1.2e-05 25.3 0.3 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 OEU20548.1 - 1.9e-28 97.9 15.6 2.3e-07 30.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 OEU20548.1 - 4.8e-24 84.7 0.3 1.1e-23 83.6 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OEU20548.1 - 0.00068 19.7 1.0 0.015 15.4 0.1 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB_3 PF16017.5 OEU20548.1 - 0.002 18.2 0.1 0.0041 17.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain WW PF00397.26 OEU20550.1 - 1.8e-12 47.1 0.6 5.5e-12 45.6 0.6 2.0 1 0 0 1 1 1 1 WW domain Inhibitor_I53 PF11714.8 OEU20550.1 - 0.52 10.5 2.8 1.5 9.0 2.8 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin TPD PF14811.6 OEU20551.1 - 6.2e-39 133.0 0.0 1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif MBD PF01429.19 OEU20551.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain TFIIA PF03153.13 OEU20553.1 - 0.027 14.5 64.7 0.045 13.7 64.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 OEU20553.1 - 0.034 12.5 28.7 0.037 12.3 28.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 OEU20553.1 - 1.5 7.4 28.9 1.6 7.4 28.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDRGK PF09756.9 OEU20553.1 - 3.2 7.3 46.3 6.8 6.2 46.3 1.5 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.9 OEU20553.1 - 4.4 5.5 57.7 4.9 5.3 57.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 OEU20553.1 - 5.2 4.0 35.8 5.7 3.9 35.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 OEU20553.1 - 8.7 5.3 39.0 10 5.0 39.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ShK PF01549.24 OEU20554.1 - 7.1e-08 32.9 4.1 1e-07 32.4 4.1 1.2 1 0 0 1 1 1 1 ShK domain-like Cyt-b5 PF00173.28 OEU20555.1 - 4e-11 42.9 0.0 6.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CTP_transf_like PF01467.26 OEU20556.1 - 1.9e-30 106.0 0.0 2.3e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OEU20556.1 - 0.0055 16.6 0.4 8.1 6.3 0.2 3.1 2 1 0 2 2 2 2 FAD synthetase Med6 PF04934.14 OEU20557.1 - 1.9e-20 73.0 0.0 2.7e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component GTP_EFTU PF00009.27 OEU20558.1 - 8.1e-51 172.3 0.0 9.1e-49 165.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OEU20558.1 - 1.2e-18 66.9 0.0 2.5e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OEU20558.1 - 4.7e-17 61.8 0.2 1e-16 60.8 0.2 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OEU20558.1 - 0.00019 21.8 1.0 0.00074 19.9 1.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OEU20558.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor G, domain IV AvrPtoB_bdg PF16847.5 OEU20558.1 - 0.0049 17.3 0.1 0.1 13.1 0.0 2.8 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain RF3_C PF16658.5 OEU20558.1 - 0.039 13.8 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 OEU20558.1 - 0.07 12.6 0.5 0.39 10.1 0.0 2.3 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit Flavokinase PF01687.17 OEU20559.1 - 5.4e-24 84.6 0.0 7.2e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase BDM PF10684.9 OEU20559.1 - 0.17 12.3 0.2 7.6 7.0 0.1 2.5 2 1 0 2 2 2 0 Putative biofilm-dependent modulation protein ANAPC4_WD40 PF12894.7 OEU20560.1 - 3.2e-06 27.3 0.0 0.037 14.3 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OEU20560.1 - 0.00015 22.5 3.3 7 7.7 0.1 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 OEU20560.1 - 0.0094 16.0 0.1 0.54 10.3 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Endosulfine PF04667.17 OEU20560.1 - 0.044 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Frtz PF11768.8 OEU20560.1 - 0.066 11.5 0.0 2.9 6.1 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz ShK PF01549.24 OEU20561.1 - 1.6e-21 76.5 32.0 6.2e-09 36.3 7.2 3.7 3 0 0 3 3 3 3 ShK domain-like 2OG-FeII_Oxy_3 PF13640.6 OEU20561.1 - 3.5e-15 56.7 0.0 5.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Utp14 PF04615.13 OEU20562.1 - 1e-123 414.6 82.3 1e-123 414.6 82.3 1.9 1 1 0 1 1 1 1 Utp14 protein zf-PHD-like PF15446.6 OEU20562.1 - 0.068 12.8 0.0 0.3 10.7 0.0 2.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Synaptobrevin PF00957.21 OEU20563.1 - 1.6e-25 88.7 3.9 2.4e-25 88.1 3.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OEU20563.1 - 8.7e-07 28.9 0.0 2.5e-06 27.4 0.0 1.7 1 1 1 2 2 2 1 Regulated-SNARE-like domain RIFIN PF02009.16 OEU20563.1 - 0.0014 18.6 0.5 0.0017 18.3 0.5 1.1 1 0 0 1 1 1 1 Rifin T2SSF PF00482.23 OEU20563.1 - 0.0098 15.8 0.4 0.014 15.3 0.4 1.4 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein F Tex_N PF09371.10 OEU20563.1 - 0.011 15.4 1.3 0.016 14.9 1.3 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF2976 PF11190.8 OEU20563.1 - 0.035 13.9 0.3 0.1 12.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) SoDot-IcmSS PF16848.5 OEU20563.1 - 0.043 13.8 1.3 0.071 13.1 1.3 1.3 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative TMEM154 PF15102.6 OEU20563.1 - 0.044 13.7 0.3 0.044 13.7 0.3 1.5 2 0 0 2 2 2 0 TMEM154 protein family Peptidase_M56 PF05569.11 OEU20563.1 - 0.075 12.2 1.5 0.1 11.8 1.0 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 TMF_TATA_bd PF12325.8 OEU20563.1 - 0.075 13.2 3.1 0.087 13.0 2.1 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.13 OEU20563.1 - 0.13 11.8 2.1 0.26 10.8 2.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region Orf78 PF06024.12 OEU20563.1 - 0.18 12.1 2.1 0.19 12.0 0.8 1.6 1 1 1 2 2 2 0 Orf78 (ac78) DUF5383 PF17355.2 OEU20563.1 - 0.28 11.6 4.8 0.15 12.5 1.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5383) FeoB_associated PF12669.7 OEU20563.1 - 1.8 9.0 4.4 5 7.6 4.4 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Adap_comp_sub PF00928.21 OEU20564.1 - 1.3e-13 51.0 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OEU20564.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Pkinase_Tyr PF07714.17 OEU20566.1 - 2.4e-30 105.7 0.0 2.8e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OEU20566.1 - 1.3e-27 96.8 0.0 1.9e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_6 PF12697.7 OEU20567.1 - 8.7e-14 52.6 0.0 1.5e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU20567.1 - 1.7e-09 37.3 0.0 8.8e-08 31.7 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU20567.1 - 2.6e-09 37.1 0.0 6.7e-08 32.5 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold LIP PF03583.14 OEU20567.1 - 0.04 13.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase LIDHydrolase PF10230.9 OEU20567.1 - 0.074 12.6 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Esterase PF00756.20 OEU20567.1 - 0.086 12.5 0.1 0.24 11.0 0.1 1.7 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 OEU20567.1 - 0.1 12.5 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal 2OG-FeII_Oxy_2 PF13532.6 OEU20568.1 - 1.1e-06 29.0 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PSII_BNR PF14870.6 OEU20569.1 - 3e-123 410.9 4.0 3.7e-123 410.6 4.0 1.1 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 OEU20569.1 - 5.2e-10 37.8 4.1 1.2 9.5 0.1 5.5 5 0 0 5 5 5 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 OEU20569.1 - 4e-06 25.9 0.7 0.0007 18.5 0.1 3.0 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, COX15-CtaA PF02628.15 OEU20570.1 - 1.7e-55 188.4 4.3 2.1e-55 188.1 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PseudoU_synth_2 PF00849.22 OEU20571.1 - 2.8e-27 95.8 0.0 4.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OEU20571.1 - 0.039 13.7 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 S4 domain RNA_pol_A_bac PF01000.26 OEU20572.1 - 3.3e-22 79.0 0.1 1.5e-21 76.8 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OEU20572.1 - 9.4e-21 73.0 0.0 1.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PTPLA PF04387.14 OEU20573.1 - 1e-39 135.9 4.8 1.8e-39 135.1 4.8 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_hydro_31 PF01055.26 OEU20575.1 - 8e-139 463.6 8.1 1.1e-138 463.1 8.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OEU20575.1 - 1.9e-18 66.6 4.0 8.3e-18 64.5 0.1 3.4 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 OEU20575.1 - 0.00046 20.4 0.7 0.001 19.3 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) ArfGap PF01412.18 OEU20576.1 - 4.2e-33 113.9 0.1 5e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 OEU20576.1 - 0.0092 15.9 0.8 0.14 12.1 0.1 2.5 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger FrhB_FdhB_C PF04432.13 OEU20576.1 - 0.057 13.2 0.1 0.089 12.6 0.1 1.3 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus WD40 PF00400.32 OEU20577.1 - 6.6e-17 61.6 10.0 1.3e-05 25.8 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20577.1 - 6.7e-10 39.1 0.1 0.16 12.3 0.0 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU20577.1 - 7.4e-06 25.2 0.1 0.0064 15.5 0.0 2.5 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OEU20577.1 - 0.00052 20.0 0.2 0.99 9.3 0.0 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF1406 PF07190.11 OEU20577.1 - 0.0039 17.1 0.1 3.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1406) UCMA PF17085.5 OEU20577.1 - 0.063 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Peptidase_C48 PF02902.19 OEU20578.1 - 6.3e-35 121.0 1.7 8e-35 120.6 1.7 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 OEU20578.1 - 0.00072 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Adenovirus endoprotease CD20 PF04103.15 OEU20579.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 CD20-like family DUF4834 PF16118.5 OEU20580.1 - 0.12 13.3 2.2 17 6.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 OEU20580.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.6 2 1 0 2 2 2 0 Orf78 (ac78) PfkB PF00294.24 OEU20583.1 - 8.8e-10 38.4 0.0 3.7e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase EB1 PF03271.17 OEU20585.1 - 3.9e-12 46.2 0.7 7.6e-12 45.3 0.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OEU20585.1 - 7.8e-05 22.8 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CENP-F_N PF10481.9 OEU20585.1 - 0.036 13.7 0.3 0.063 12.9 0.3 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain CAMSAP_CH PF11971.8 OEU20585.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DUF4954 PF16314.5 OEU20586.1 - 9.7e-15 53.7 0.4 2.7e-14 52.3 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) APH PF01636.23 OEU20587.1 - 3.2e-32 112.4 0.0 4.7e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OEU20587.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OEU20587.1 - 1.1e-05 25.1 0.1 4.7e-05 23.1 0.0 2.0 3 0 0 3 3 3 1 Choline/ethanolamine kinase RIO1 PF01163.22 OEU20587.1 - 0.0017 18.0 0.1 1.6 8.3 0.1 2.3 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.14 OEU20587.1 - 0.089 12.0 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Fructosamine kinase Proteasome PF00227.26 OEU20588.1 - 1.5e-35 122.4 0.7 1.7e-35 122.2 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit Med21 PF11221.8 OEU20589.1 - 3.3e-14 53.4 0.2 8e-14 52.1 0.2 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 OEU20589.1 - 0.0023 18.0 0.3 0.0069 16.5 0.4 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Sec5 PF15469.6 OEU20589.1 - 0.024 14.5 0.7 0.035 13.9 0.7 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF4375 PF14300.6 OEU20589.1 - 0.11 12.8 0.7 0.51 10.6 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) Phage_NinH PF06322.11 OEU20589.1 - 0.11 12.4 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Phage NinH protein AAA_2 PF07724.14 OEU20590.1 - 1.2e-38 132.9 0.0 2.7e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OEU20590.1 - 7.7e-10 39.3 0.0 1.5e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OEU20590.1 - 8.3e-09 35.4 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 OEU20590.1 - 1.8e-05 24.0 0.1 3.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_18 PF13238.6 OEU20590.1 - 0.00094 19.7 0.0 0.0026 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OEU20590.1 - 0.0017 18.9 0.1 0.0058 17.2 0.1 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OEU20590.1 - 0.0019 18.5 0.1 0.016 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU20590.1 - 0.003 17.5 0.2 0.0098 15.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU20590.1 - 0.0035 16.8 0.0 0.076 12.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OEU20590.1 - 0.0092 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 OEU20590.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 OEU20590.1 - 0.022 14.6 0.0 0.092 12.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_PrkA PF08298.11 OEU20590.1 - 0.032 13.1 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain RuvB_N PF05496.12 OEU20590.1 - 0.036 13.8 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 OEU20590.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OEU20590.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 OEU20590.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OEU20590.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OEU20590.1 - 0.088 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 OEU20590.1 - 0.11 12.8 0.1 0.4 11.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain Acetyltransf_3 PF13302.7 OEU20592.1 - 0.0069 17.1 0.0 0.0084 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OEU20592.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rer1 PF03248.13 OEU20593.1 - 1.1e-62 210.8 10.0 1.3e-62 210.5 10.0 1.1 1 0 0 1 1 1 1 Rer1 family E7R PF17467.2 OEU20593.1 - 0.017 15.2 0.3 0.017 15.2 0.3 1.7 2 0 0 2 2 2 0 Viral Protein E7 Chloroa_b-bind PF00504.21 OEU20595.1 - 1e-29 104.1 0.1 1.4e-29 103.7 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ribosomal_60s PF00428.19 OEU20596.1 - 4.3e-09 36.8 0.8 5.9e-09 36.4 0.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1456 PF07308.13 OEU20596.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) EIF_2_alpha PF07541.12 OEU20597.1 - 4.1e-38 130.1 0.1 1.7e-37 128.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OEU20597.1 - 9e-14 51.6 0.5 1.9e-13 50.5 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Trm112p PF03966.16 OEU20598.1 - 9.9e-11 42.1 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein F-box-like PF12937.7 OEU20599.1 - 0.0085 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF4661 PF15576.6 OEU20599.1 - 1.1 9.1 5.7 2.5 7.9 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) MFS_5 PF05631.14 OEU20600.1 - 2.3e-47 161.6 5.9 2.8e-47 161.3 5.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OEU20600.1 - 2.5e-14 53.0 13.0 8.6e-14 51.2 13.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily LRR_6 PF13516.6 OEU20601.1 - 1.4e-33 112.1 15.9 0.00025 20.8 0.4 9.9 11 0 0 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.7 OEU20601.1 - 1.1e-09 38.4 3.3 0.17 12.3 0.4 6.0 5 3 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU20601.1 - 5.4e-06 26.2 3.1 2.5e+02 2.9 0.0 8.8 10 1 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 OEU20601.1 - 0.018 14.8 14.6 34 4.3 0.3 6.7 4 4 0 4 4 4 0 Leucine rich repeat Amino_oxidase PF01593.24 OEU20602.1 - 1.5e-12 47.6 0.0 6.6e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU20602.1 - 4.2e-06 26.9 0.0 8.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU20602.1 - 5.2e-06 25.9 0.0 0.03 13.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU20602.1 - 0.0035 17.0 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OEU20602.1 - 0.0038 16.0 0.0 1.1 7.9 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 OEU20602.1 - 0.023 14.7 0.1 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OEU20602.1 - 0.18 12.4 0.0 3.3 8.3 0.0 2.9 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 OEU20603.1 - 0.0022 18.5 0.0 0.012 16.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter DUF5378 PF17349.2 OEU20603.1 - 0.066 12.5 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) SMC_N PF02463.19 OEU20603.1 - 0.18 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OEU20604.1 - 4.4e-06 27.3 0.4 6.3e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OEU20604.1 - 0.00013 22.4 0.2 0.00054 20.5 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 OEU20604.1 - 0.00024 20.8 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OEU20604.1 - 0.0024 17.8 0.1 0.0099 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 OEU20604.1 - 0.05 13.4 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_19 PF13245.6 OEU20604.1 - 0.052 13.9 0.1 0.18 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 OEU20604.1 - 0.055 12.3 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SMC_N PF02463.19 OEU20604.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TMF_TATA_bd PF12325.8 OEU20604.1 - 0.17 12.1 2.1 5.6 7.2 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HSBP1 PF06825.12 OEU20604.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 WD40 PF00400.32 OEU20606.1 - 6.3e-40 134.4 18.7 2.4e-08 34.5 0.5 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20606.1 - 1.5e-10 41.2 0.0 0.059 13.7 0.0 5.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OEU20606.1 - 0.0014 18.9 0.7 0.83 9.9 0.1 2.9 2 1 0 3 3 3 2 WD40 associated region in TFIID subunit, NTD2 domain WD40_like PF17005.5 OEU20606.1 - 0.012 15.0 0.0 0.065 12.5 0.0 2.0 1 1 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 OEU20606.1 - 0.019 13.9 0.0 14 4.6 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF2_N PF00176.23 OEU20607.1 - 3.6e-23 81.9 0.3 3.5e-22 78.6 0.3 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OEU20607.1 - 8.2e-18 64.8 0.0 2.9e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 OEU20607.1 - 0.00052 20.3 0.7 0.0017 18.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pan3_PK PF18101.1 OEU20608.1 - 4.5e-49 166.0 0.0 7.8e-49 165.2 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Phage_int_SAM_1 PF02899.17 OEU20608.1 - 0.0037 17.5 0.1 0.11 12.8 0.1 3.0 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 OEU20608.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DnaJ_C PF01556.18 OEU20609.1 - 3.5e-34 118.0 0.4 4.8e-34 117.6 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OEU20609.1 - 4.1e-23 81.3 2.9 6.8e-23 80.6 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2997 PF11211.8 OEU20610.1 - 2.2e-17 62.6 0.2 4.7e-17 61.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) Serglycin PF04360.12 OEU20610.1 - 0.22 11.5 2.7 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Serglycin LMBR1 PF04791.16 OEU20612.1 - 2.3 7.0 3.1 2.5 6.9 3.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HMG_box PF00505.19 OEU20615.1 - 0.0001 22.6 0.0 0.00035 20.9 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU20615.1 - 0.00051 20.6 0.2 0.0017 18.9 0.1 1.9 2 0 0 2 2 2 1 HMG-box domain YajC PF02699.15 OEU20616.1 - 0.061 13.2 2.7 0.38 10.7 2.7 2.4 1 0 0 1 1 1 0 Preprotein translocase subunit Adaptin_N PF01602.20 OEU20617.1 - 3.1e-99 332.9 0.3 4.5e-99 332.4 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OEU20617.1 - 1.5e-18 67.0 0.0 2.9e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 OEU20617.1 - 2e-10 40.9 0.1 5.3e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 OEU20617.1 - 9.8e-08 32.3 0.0 6.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Caprin-1_dimer PF18293.1 OEU20617.1 - 0.13 12.7 0.6 9.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Caprin-1 dimerization domain EGF PF00008.27 OEU20618.1 - 6.2e-05 23.2 135.1 0.067 13.5 4.4 13.2 12 1 0 12 12 12 9 EGF-like domain EGF_2 PF07974.13 OEU20618.1 - 0.00025 21.3 14.4 0.0061 16.9 9.9 12.4 11 3 0 11 11 11 7 EGF-like domain RNA_pol_L_2 PF13656.6 OEU20619.1 - 1.6e-24 85.4 0.0 2.1e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OEU20619.1 - 1.6e-08 33.8 0.0 2.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cep57_MT_bd PF06657.13 OEU20619.1 - 0.14 12.7 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 AAA_25 PF13481.6 OEU20620.1 - 1.1e-19 70.7 0.1 3.6e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OEU20620.1 - 4.2e-12 45.9 0.0 8.6e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 KaiC Rubredoxin_2 PF18073.1 OEU20620.1 - 5.6e-11 42.0 8.2 1.2e-10 40.9 8.2 1.6 1 0 0 1 1 1 1 Rubredoxin metal binding domain DnaB_C PF03796.15 OEU20620.1 - 8.2e-11 41.7 0.0 3.9e-09 36.2 0.0 2.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ChlI PF13541.6 OEU20620.1 - 0.0001 22.2 0.1 0.00024 20.9 0.1 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OEU20620.1 - 0.0001 22.7 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Rad51 PF08423.11 OEU20620.1 - 0.0003 20.1 0.1 0.0035 16.6 0.0 2.1 2 0 0 2 2 2 1 Rad51 AAA_22 PF13401.6 OEU20620.1 - 0.00038 20.7 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OEU20620.1 - 0.00061 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Lon_C PF05362.13 OEU20620.1 - 0.0018 17.9 0.1 0.0076 15.8 0.0 2.1 3 0 0 3 3 2 1 Lon protease (S16) C-terminal proteolytic domain RecA PF00154.21 OEU20620.1 - 0.0052 16.3 0.3 0.013 15.0 0.2 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 OEU20620.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_P4 PF11602.8 OEU20620.1 - 0.0089 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 ATPase P4 of dsRNA bacteriophage phi-12 zf-RING_10 PF16685.5 OEU20620.1 - 0.011 15.9 0.5 0.022 14.9 0.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 AAA_24 PF13479.6 OEU20620.1 - 0.013 15.2 0.0 0.67 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OEU20620.1 - 0.017 15.6 0.1 0.027 15.0 0.1 1.3 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OEU20620.1 - 0.019 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OEU20620.1 - 0.027 15.0 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Isochorismatase PF00857.20 OEU20620.1 - 0.083 13.1 0.2 0.17 12.0 0.0 1.6 2 0 0 2 2 1 0 Isochorismatase family RNA_helicase PF00910.22 OEU20620.1 - 0.086 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OEU20620.1 - 0.09 12.7 0.2 0.17 11.8 0.2 1.5 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 OEU20620.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 OEU20620.1 - 0.1 11.8 0.1 0.2 10.8 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain KTI12 PF08433.10 OEU20620.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 OEU20620.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TackOD1 PF18551.1 OEU20620.1 - 0.24 11.1 0.3 0.38 10.4 0.3 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Paf67 PF10255.9 OEU20621.1 - 4.6e-83 279.5 0.0 3e-82 276.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF4337 PF14235.6 OEU20622.1 - 0.07 13.2 0.2 0.098 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-Hacid_dh_C PF02826.19 OEU20623.1 - 7.5e-28 97.1 0.0 1.2e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OEU20623.1 - 1.2e-18 67.0 0.2 2.5e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OEU20623.1 - 0.002 18.3 0.1 0.0043 17.2 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OEU20623.1 - 0.0053 16.3 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 OEU20623.1 - 0.0054 16.5 0.2 0.018 14.8 0.1 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 OEU20623.1 - 0.022 15.3 0.3 0.067 13.8 0.3 1.8 1 1 0 1 1 1 0 ACT domain Rib_5-P_isom_A PF06026.14 OEU20623.1 - 0.072 12.7 0.2 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) AlaDh_PNT_C PF01262.21 OEU20623.1 - 0.1 11.9 2.2 0.13 11.5 0.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OEU20624.1 - 6.7e-28 97.2 0.0 1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OEU20624.1 - 3.8e-15 55.7 0.0 5.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OEU20624.1 - 0.0016 18.7 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OEU20624.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 OEU20624.1 - 0.048 14.2 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain NUC153 PF08159.12 OEU20625.1 - 1.4e-08 34.4 0.9 2.7e-08 33.5 0.9 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 OEU20625.1 - 1.1e-06 29.2 1.7 0.31 12.0 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20625.1 - 0.0092 16.3 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Chloroa_b-bind PF00504.21 OEU20626.1 - 3.4e-34 118.7 0.1 4.2e-34 118.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Patatin PF01734.22 OEU20627.1 - 1.5e-19 71.0 0.5 3.5e-19 69.8 0.5 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 OEU20627.1 - 7.4e-11 42.0 0.0 8.1e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ribosomal_S25 PF03297.15 OEU20627.1 - 0.038 14.2 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 S25 ribosomal protein GcpE PF04551.14 OEU20628.1 - 2.9e-147 490.3 0.0 5.9e-147 489.3 0.0 1.5 1 1 0 1 1 1 1 GcpE protein zf-RING_7 PF02591.15 OEU20628.1 - 0.16 12.2 0.5 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 C4-type zinc ribbon domain Sgf11 PF08209.11 OEU20628.1 - 0.26 10.9 0.7 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Methyltransf_15 PF09445.10 OEU20629.1 - 2.5e-08 33.7 0.0 5.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RP-C_C PF11800.8 OEU20629.1 - 3.7 7.6 6.6 3.1 7.9 1.1 2.9 2 0 0 2 2 2 0 Replication protein C C-terminal region RabGAP-TBC PF00566.18 OEU20630.1 - 3.1e-55 187.2 1.2 3.8e-55 186.9 1.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UMP1 PF05348.11 OEU20631.1 - 1e-16 61.2 0.2 1.3e-16 60.8 0.2 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 LSM PF01423.22 OEU20632.1 - 7.5e-21 73.6 0.4 1e-20 73.2 0.4 1.2 1 0 0 1 1 1 1 LSM domain SpoVT_C PF15714.5 OEU20633.1 - 0.045 13.8 0.2 0.082 13.0 0.2 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Aldo_ket_red PF00248.21 OEU20634.1 - 1.7e-12 47.1 0.1 4.4e-12 45.8 0.1 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4194 PF13835.6 OEU20635.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) DUF5302 PF17227.2 OEU20635.1 - 0.63 11.1 2.7 1 10.4 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5302) SUIM_assoc PF16619.5 OEU20636.1 - 0.089 12.9 0.5 0.089 12.9 0.5 2.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Solute_trans_a PF03619.16 OEU20637.1 - 1.3e-90 303.6 17.2 1.4e-90 303.4 17.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Toxin_12 PF07740.12 OEU20640.1 - 0.00093 19.8 6.5 0.002 18.8 6.5 1.6 1 0 0 1 1 1 1 Ion channel inhibitory toxin UPF0506 PF11703.8 OEU20640.1 - 0.049 14.0 5.5 0.11 12.8 5.5 1.6 1 0 0 1 1 1 0 UPF0506 Toxin_35 PF10530.9 OEU20640.1 - 0.21 11.6 3.2 0.41 10.7 3.2 1.4 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold AZUL PF16558.5 OEU20640.1 - 1.1 9.6 6.8 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Conotoxin PF02950.17 OEU20640.1 - 2.2 9.3 8.4 6.7 7.8 4.1 2.4 2 0 0 2 2 2 0 Conotoxin TGT PF01702.18 OEU20641.1 - 1.5e-109 366.4 0.0 1.8e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PPR_2 PF13041.6 OEU20644.1 - 9.4e-32 109.0 0.5 1.7e-10 40.9 0.0 4.1 1 1 3 4 4 4 4 PPR repeat family PPR PF01535.20 OEU20644.1 - 2.5e-27 93.1 4.0 5.2e-06 26.3 0.1 4.7 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.6 OEU20644.1 - 1.6e-23 82.6 0.0 5.2e-08 32.8 0.0 3.7 2 1 0 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU20644.1 - 8.2e-15 54.2 0.2 0.00077 19.1 0.1 5.9 5 2 0 5 5 5 5 PPR repeat PPR_long PF17177.4 OEU20644.1 - 4.6e-12 45.8 0.1 6e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PYRIN PF02758.16 OEU20644.1 - 0.0056 16.8 0.2 11 6.3 0.0 3.8 4 0 0 4 4 4 1 PAAD/DAPIN/Pyrin domain HTH_45 PF14947.6 OEU20644.1 - 0.0097 15.9 0.0 0.59 10.2 0.0 3.1 2 1 1 3 3 3 1 Winged helix-turn-helix TPR_14 PF13428.6 OEU20644.1 - 0.01 16.6 0.3 50 5.1 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4256 PF14066.6 OEU20644.1 - 0.011 15.5 0.0 0.31 10.7 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4256) TPR_7 PF13176.6 OEU20644.1 - 0.014 15.4 1.6 11 6.3 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DapB_N PF01113.20 OEU20645.1 - 8.1 6.6 8.8 1.4 9.1 1.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MORN PF02493.20 OEU20647.1 - 1.8e-45 150.2 54.5 1.9e-09 36.8 0.4 8.0 8 0 0 8 8 8 7 MORN repeat Tudor_2 PF18104.1 OEU20647.1 - 0.0096 15.6 11.2 0.056 13.1 0.2 4.6 4 0 0 4 4 4 2 Jumonji domain-containing protein 2A Tudor domain PSI_8 PF00796.18 OEU20648.1 - 2e-07 30.7 12.1 3.9e-07 29.8 12.1 1.5 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VIII SpoIIIAH PF12685.7 OEU20649.1 - 0.032 14.1 5.7 0.04 13.7 5.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SR-25 PF10500.9 OEU20649.1 - 0.4 10.2 22.2 0.46 10.0 22.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 OEU20649.1 - 9.5 4.9 9.2 12 4.6 9.2 1.0 1 0 0 1 1 1 0 Presenilin PHD PF00628.29 OEU20650.1 - 8.9e-10 38.3 23.0 4.3e-06 26.5 14.2 3.3 3 0 0 3 3 3 2 PHD-finger Rtf2 PF04641.12 OEU20650.1 - 0.00066 19.1 0.9 0.00066 19.1 0.9 6.3 4 1 3 7 7 7 1 Rtf2 RING-finger C1_1 PF00130.22 OEU20650.1 - 8.7 6.3 16.9 0.063 13.2 0.6 3.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_13 PF13880.6 OEU20651.1 - 3.6e-19 68.5 0.0 6.5e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OEU20651.1 - 0.00097 18.9 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 OEU20651.1 - 0.0087 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU20651.1 - 0.027 14.9 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU20651.1 - 0.046 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSF_DNA-bind PF00447.17 OEU20652.1 - 2.2e-17 63.4 0.0 3.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding CorA PF01544.18 OEU20653.1 - 1.4e-06 27.9 3.0 6.8e-06 25.6 3.1 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3870 PF12986.7 OEU20653.1 - 0.033 14.4 0.2 0.13 12.5 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3870) Pkinase PF00069.25 OEU20654.1 - 4.3e-53 180.3 0.0 9.1e-33 113.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20654.1 - 2.1e-26 92.7 0.0 3.7e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OEU20654.1 - 5.4e-05 22.6 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OEU20654.1 - 0.00089 18.7 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OEU20654.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OEU20654.1 - 0.039 13.9 0.2 0.23 11.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OEU20654.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Atg14 PF10186.9 OEU20654.1 - 4.1 6.4 8.0 8.4 5.4 8.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pro_isomerase PF00160.21 OEU20655.1 - 8.2e-43 146.4 0.0 1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbP PF01789.16 OEU20656.1 - 9.3e-18 64.8 0.1 1.2e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 PsbP TAT_signal PF10518.9 OEU20656.1 - 0.14 12.0 1.5 0.29 11.0 1.5 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence ATP_bind_1 PF03029.17 OEU20657.1 - 1.1e-52 179.2 0.2 8.1e-38 130.6 0.0 2.8 3 1 0 3 3 3 2 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OEU20657.1 - 0.0028 18.2 0.1 0.01 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OEU20657.1 - 0.0064 16.5 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 OEU20657.1 - 0.0073 16.7 0.1 0.14 12.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 OEU20657.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 OEU20657.1 - 0.045 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 OEU20657.1 - 0.073 13.2 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OEU20657.1 - 0.08 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 OEU20657.1 - 0.11 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OEU20657.1 - 0.12 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HSP90 PF00183.18 OEU20658.1 - 2.2e-159 531.7 13.6 3.2e-159 531.1 13.6 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OEU20658.1 - 1.7e-13 51.1 0.1 5.8e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OEU20658.1 - 1e-10 41.6 0.2 5e-10 39.3 0.2 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LRR_9 PF14580.6 OEU20659.1 - 1.5e-37 128.8 0.2 5.5e-35 120.4 0.2 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OEU20659.1 - 5.4e-07 29.3 6.1 1.8e-05 24.4 1.4 3.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OEU20659.1 - 0.001 19.4 4.5 0.18 12.3 1.3 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU20659.1 - 0.059 13.4 1.4 2.8 8.2 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OEU20659.1 - 0.41 11.4 2.2 42 5.3 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich Repeat FAM76 PF16046.5 OEU20661.1 - 0.098 12.0 3.1 0.14 11.5 3.1 1.2 1 0 0 1 1 1 0 FAM76 protein POX PF07526.11 OEU20661.1 - 0.39 11.3 10.8 1.6 9.3 10.6 1.9 1 1 0 1 1 1 0 Associated with HOX HA PF03457.14 OEU20663.1 - 9.3e-33 112.4 7.8 2.4e-10 40.6 0.1 3.8 3 0 0 3 3 3 3 Helicase associated domain DUF1249 PF06853.12 OEU20663.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) HRXXH PF13933.6 OEU20663.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.3 3 0 0 3 3 3 0 Putative peptidase family DapB_N PF01113.20 OEU20664.1 - 0.85 9.7 4.6 0.28 11.3 0.6 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus HypA PF01155.19 OEU20665.1 - 0.0044 17.0 0.3 0.0058 16.6 0.3 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 OEU20665.1 - 0.019 14.4 1.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding PaRep2a PF07903.11 OEU20665.1 - 0.035 13.9 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 PaRep2a protein ADK_lid PF05191.14 OEU20665.1 - 0.058 13.4 2.7 0.13 12.2 2.7 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid Rubredoxin PF00301.20 OEU20665.1 - 0.059 13.4 7.5 3.3 7.8 7.5 2.3 1 1 0 1 1 1 0 Rubredoxin zf-RRN7 PF11781.8 OEU20665.1 - 0.099 12.3 3.6 0.79 9.5 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 T2SSC PF11356.8 OEU20665.1 - 0.13 12.1 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system protein C zf-RanBP PF00641.18 OEU20665.1 - 0.16 11.3 2.1 0.4 10.0 0.1 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_1 PF00130.22 OEU20665.1 - 0.41 10.6 3.2 8.6 6.3 2.9 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin_2 PF18073.1 OEU20665.1 - 0.89 9.3 5.9 1.3 8.8 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C2H2 PF00096.26 OEU20665.1 - 2.3 8.9 4.5 6.6 7.4 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type PPR_2 PF13041.6 OEU20666.1 - 6.3e-12 45.5 0.1 0.001 19.2 0.0 6.4 7 1 0 7 7 7 2 PPR repeat family PPR_1 PF12854.7 OEU20666.1 - 3.7e-07 29.7 1.1 0.66 9.7 0.0 6.2 5 1 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 OEU20666.1 - 0.00012 22.1 3.5 16 5.7 0.0 6.6 7 1 0 7 7 7 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU20666.1 - 0.017 14.5 1.9 0.12 11.8 0.2 2.9 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP FTCD_C PF04961.12 OEU20666.1 - 0.27 11.0 4.4 2.6 7.8 0.1 3.3 3 1 0 3 3 3 0 Formiminotransferase-cyclodeaminase PPR PF01535.20 OEU20666.1 - 0.77 10.2 18.0 50 4.5 0.3 8.8 9 2 0 9 9 9 0 PPR repeat F-actin_cap_A PF01267.17 OEU20667.1 - 1e-28 100.5 0.2 6.3e-26 91.4 0.1 2.2 1 1 1 2 2 2 2 F-actin capping protein alpha subunit ATP_bind_1 PF03029.17 OEU20668.1 - 5.1e-67 226.2 0.2 6.5e-67 225.8 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OEU20668.1 - 6.2e-07 29.1 0.0 4.3e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OEU20668.1 - 6.3e-06 26.7 0.0 3e-05 24.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 OEU20668.1 - 2e-05 24.3 0.0 0.061 12.9 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OEU20668.1 - 2.4e-05 24.4 0.0 0.0013 18.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OEU20668.1 - 9e-05 21.8 0.0 0.00073 18.8 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 OEU20668.1 - 0.0001 22.3 0.0 0.95 9.3 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase NB-ARC PF00931.22 OEU20668.1 - 0.00014 21.1 0.0 0.00028 20.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain SRPRB PF09439.10 OEU20668.1 - 0.00015 21.3 0.0 0.034 13.6 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 OEU20668.1 - 0.00017 22.1 0.0 0.0014 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 OEU20668.1 - 0.00026 20.5 0.0 0.078 12.5 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B ATPase_2 PF01637.18 OEU20668.1 - 0.00039 20.4 0.0 0.0034 17.3 0.0 2.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OEU20668.1 - 0.00048 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Roc PF08477.13 OEU20668.1 - 0.00087 19.5 0.1 0.051 13.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 OEU20668.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 OEU20668.1 - 0.0022 17.4 0.0 0.085 12.3 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_22 PF13401.6 OEU20668.1 - 0.0026 18.1 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU20668.1 - 0.0028 17.6 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 OEU20668.1 - 0.0028 17.4 0.0 0.025 14.3 0.0 2.5 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OEU20668.1 - 0.0028 17.4 0.5 0.012 15.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 OEU20668.1 - 0.0036 16.8 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein SRP54 PF00448.22 OEU20668.1 - 0.0091 15.6 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 OEU20668.1 - 0.013 14.5 0.0 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 OEU20668.1 - 0.014 15.9 0.3 0.23 12.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 OEU20668.1 - 0.017 14.4 0.0 0.061 12.6 0.0 1.9 3 0 0 3 3 2 0 Septin Ras PF00071.22 OEU20668.1 - 0.017 14.7 0.0 12 5.4 0.0 2.6 2 1 1 3 3 3 0 Ras family AAA_33 PF13671.6 OEU20668.1 - 0.018 15.2 0.1 0.018 15.2 0.1 1.9 2 1 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 OEU20668.1 - 0.021 14.6 0.0 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 OEU20668.1 - 0.027 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 OEU20668.1 - 0.033 14.3 0.0 0.29 11.2 0.0 2.3 3 0 0 3 3 3 0 Helicase HerA, central domain RNA_helicase PF00910.22 OEU20668.1 - 0.036 14.5 0.0 0.45 10.9 0.0 2.5 2 1 1 3 3 3 0 RNA helicase AAA_14 PF13173.6 OEU20668.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OEU20668.1 - 0.045 13.1 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OEU20668.1 - 0.055 13.0 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 OEU20668.1 - 0.087 13.1 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain Ploopntkinase3 PF18751.1 OEU20668.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 OEU20668.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 OEU20668.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 OEU20668.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OEU20668.1 - 0.16 12.4 0.2 1 9.8 0.0 2.3 3 0 0 3 3 2 0 AAA domain DUF2070 PF09843.9 OEU20669.1 - 1.9 6.7 9.4 2.8 6.1 9.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ank_4 PF13637.6 OEU20670.1 - 1.4e-08 35.1 0.1 0.00016 22.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU20670.1 - 1.2e-07 32.2 0.0 2.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU20670.1 - 7.6e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU20670.1 - 3.4e-05 23.9 0.1 0.00084 19.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU20670.1 - 0.00041 20.7 0.0 0.0033 17.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 OEU20670.1 - 0.041 14.8 0.0 0.098 13.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily LON_substr_bdg PF02190.16 OEU20671.1 - 0.00017 21.6 0.7 0.00039 20.4 0.5 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF4510 PF14971.6 OEU20671.1 - 0.01 16.2 1.5 0.026 14.9 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) MAP PF03642.13 OEU20671.1 - 0.042 14.2 0.0 2.5 8.5 0.0 3.1 3 0 0 3 3 3 0 MAP domain Syntaxin_2 PF14523.6 OEU20671.1 - 0.089 13.2 1.9 0.58 10.6 0.1 2.5 3 0 0 3 3 3 0 Syntaxin-like protein DUF1690 PF07956.11 OEU20671.1 - 0.81 10.1 6.7 3.2 8.2 5.1 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) OmpH PF03938.14 OEU20671.1 - 4.1 7.7 12.8 12 6.2 12.6 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 OEU20672.1 - 1.5e-23 82.4 0.2 1.2e-10 41.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU20672.1 - 0.018 15.1 0.1 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif TFIIF_alpha PF05793.12 OEU20672.1 - 0.12 11.0 26.1 0.15 10.6 26.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 OEU20672.1 - 0.21 10.3 5.5 0.24 10.1 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 OEU20672.1 - 0.39 9.9 5.3 0.46 9.6 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 OEU20672.1 - 0.64 8.2 19.4 0.77 7.9 19.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4140 PF13600.6 OEU20672.1 - 0.7 10.4 3.3 9.2 6.8 0.0 2.9 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Dsh_C PF12316.8 OEU20672.1 - 2.4 8.5 8.6 4 7.8 8.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 OEU20672.1 - 3.1 6.5 13.0 4.2 6.0 13.0 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 OEU20672.1 - 4.5 7.2 15.9 7 6.6 15.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Raftlin PF15250.6 OEU20672.1 - 5.7 5.6 10.5 7.7 5.1 10.5 1.1 1 0 0 1 1 1 0 Raftlin Atg8 PF02991.16 OEU20674.1 - 7.7e-48 161.0 0.0 9.1e-48 160.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OEU20674.1 - 4.9e-05 23.7 0.0 6.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Thiolase_N PF00108.23 OEU20676.1 - 3.2e-78 262.7 0.6 4.9e-78 262.1 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OEU20676.1 - 4e-43 146.0 0.2 8.1e-43 145.0 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain LTV PF04180.14 OEU20677.1 - 7.6e-07 29.2 19.7 0.0011 18.8 1.4 3.2 1 1 0 2 2 2 2 Low temperature viability protein Mt_ATP-synt_B PF05405.14 OEU20677.1 - 0.17 11.5 1.8 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Phosphodiest PF01663.22 OEU20678.1 - 8.5e-09 35.5 0.1 1.9e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DEAD PF00270.29 OEU20679.1 - 2.3e-47 161.0 0.8 9e-47 159.1 0.2 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU20679.1 - 2e-31 108.6 0.4 9.1e-29 100.0 0.1 2.9 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OEU20679.1 - 4.1e-07 30.2 0.0 8.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OEU20679.1 - 0.074 13.0 0.2 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain WH2 PF02205.20 OEU20680.1 - 2.3e-06 27.2 12.9 0.34 10.8 0.1 5.6 6 0 0 6 6 6 4 WH2 motif DUF4055 PF13264.6 OEU20680.1 - 0.026 14.7 2.8 0.075 13.2 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) Dynein_IC2 PF11540.8 OEU20680.1 - 0.038 14.0 0.2 2.6 8.1 0.2 2.8 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 MAT1 PF06391.13 OEU20681.1 - 4.1e-27 95.4 13.0 5.7e-27 94.9 13.0 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 OEU20681.1 - 4.9e-07 29.5 5.7 1.4e-06 28.1 5.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU20681.1 - 1.5e-06 27.9 2.8 1.5e-06 27.9 2.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU20681.1 - 3.8e-06 27.1 5.2 7.5e-06 26.2 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OEU20681.1 - 1.2e-05 25.2 3.0 1.2e-05 25.2 3.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OEU20681.1 - 3.1e-05 24.0 3.1 3.1e-05 24.0 3.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OEU20681.1 - 6e-05 23.0 4.4 0.00014 21.8 4.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU20681.1 - 6.5e-05 22.7 7.6 0.00019 21.2 7.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU20681.1 - 0.00023 21.4 3.8 0.00047 20.4 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OEU20681.1 - 0.0061 16.4 8.2 0.025 14.5 8.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OEU20681.1 - 0.0061 16.4 0.3 0.012 15.4 0.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 OEU20681.1 - 0.029 14.3 0.5 0.078 12.9 0.5 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 OEU20681.1 - 0.031 14.1 2.2 0.074 12.9 2.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OEU20681.1 - 0.043 14.1 0.9 3.9 7.8 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4148 PF13663.6 OEU20681.1 - 0.17 12.1 1.0 0.4 10.9 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) zf-C3HC4_5 PF17121.5 OEU20681.1 - 0.75 9.7 4.2 2.5 8.1 4.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.6 OEU20681.1 - 6.5 6.8 7.1 0.62 10.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Lipase_3 PF01764.25 OEU20682.1 - 4.1e-18 65.6 0.0 9.6e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OEU20682.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GAPT PF11770.8 OEU20682.1 - 0.039 13.8 2.1 0.12 12.3 2.1 1.8 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Pkinase PF00069.25 OEU20683.1 - 1.8e-62 211.1 0.0 2.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20683.1 - 9.6e-30 103.7 0.0 1.3e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OEU20683.1 - 5.4e-07 28.9 0.0 7.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OEU20683.1 - 7.1e-05 22.3 0.2 0.00011 21.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OEU20683.1 - 0.007 16.3 0.1 0.022 14.7 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Imm7 PF15585.6 OEU20683.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 7 Choline_kinase PF01633.20 OEU20683.1 - 0.1 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.32 OEU20684.1 - 6.1e-17 61.7 13.7 2.8e-08 34.3 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20684.1 - 3.8e-08 33.5 0.0 9.4e-05 22.6 0.0 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU20684.1 - 0.0008 18.5 0.0 0.0046 16.0 0.0 2.2 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein GATase_2 PF00310.21 OEU20685.1 - 7e-160 532.3 0.0 9.6e-160 531.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OEU20685.1 - 4.7e-152 506.4 0.1 7.7e-152 505.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OEU20685.1 - 2.4e-103 345.4 0.0 5.4e-103 344.3 0.0 1.6 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OEU20685.1 - 3.5e-79 264.8 5.5 7e-79 263.9 5.5 1.5 1 0 0 1 1 1 1 GXGXG motif GATase_6 PF13522.6 OEU20685.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase domain FMN_dh PF01070.18 OEU20685.1 - 0.32 10.0 2.4 0.63 9.0 1.2 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Voltage_CLC PF00654.20 OEU20686.1 - 1.2e-28 100.5 41.5 9.9e-28 97.4 32.1 3.0 1 1 1 2 2 2 2 Voltage gated chloride channel ubiquitin PF00240.23 OEU20687.1 - 6.1e-34 115.6 0.4 1.2e-33 114.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 OEU20687.1 - 9.7e-19 67.3 1.4 9.7e-19 67.3 1.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OEU20687.1 - 2.8e-16 59.1 0.7 5.3e-16 58.2 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU20687.1 - 1.6e-05 25.3 0.2 7.8e-05 23.1 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU20687.1 - 0.0011 19.1 0.2 0.0024 17.9 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OEU20687.1 - 0.0039 17.1 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OEU20687.1 - 0.014 15.7 0.1 0.025 14.9 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 OEU20687.1 - 0.016 15.8 0.2 0.022 15.3 0.2 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU20687.1 - 0.059 13.4 0.7 9 6.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_M76 PF09768.9 OEU20688.1 - 2.6e-50 170.5 0.1 3e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M85 PF13678.6 OEU20688.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease Ribonuc_red_lgC PF02867.15 OEU20689.1 - 1.2e-182 608.1 0.0 1.5e-182 607.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OEU20689.1 - 2.9e-22 78.5 0.1 8.4e-22 77.0 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Ribosomal_L28 PF00830.19 OEU20690.1 - 4.5e-18 65.2 4.7 1.9e-17 63.2 2.4 2.1 2 0 0 2 2 2 1 Ribosomal L28 family Ribosomal_L10 PF00466.20 OEU20691.1 - 2.9e-18 65.8 0.0 4.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 OEU20691.1 - 9.6e-18 64.0 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P WD40 PF00400.32 OEU20692.1 - 5.9e-49 163.0 18.6 4.1e-11 43.3 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20692.1 - 4e-24 84.7 0.6 4.7e-05 23.6 0.0 5.7 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU20692.1 - 4e-09 36.6 1.9 0.00042 20.3 0.0 4.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OEU20692.1 - 1.3e-05 24.9 0.1 2.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 LisH Nbas_N PF15492.6 OEU20692.1 - 0.00011 21.7 0.1 0.1 11.9 0.0 3.4 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Pex14_N PF04695.13 OEU20692.1 - 0.00034 21.3 7.0 0.0051 17.5 0.3 2.3 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region IKI3 PF04762.12 OEU20692.1 - 0.0004 18.6 0.1 0.43 8.5 0.0 3.2 1 1 2 3 3 3 2 IKI3 family Ge1_WD40 PF16529.5 OEU20692.1 - 0.0025 16.9 0.2 5.4 5.9 0.0 4.2 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OEU20692.1 - 0.026 13.2 0.9 0.73 8.4 0.0 3.3 4 1 0 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 OEU20692.1 - 0.029 13.7 0.0 8.4 5.6 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain RAB3GAP2_N PF14655.6 OEU20692.1 - 0.087 12.1 0.2 5.9 6.0 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PRP38 PF03371.15 OEU20693.1 - 3.1e-44 150.9 0.0 4.7e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 PRP38 family adh_short PF00106.25 OEU20696.1 - 7.6e-24 84.2 0.0 6.9e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU20696.1 - 9.4e-07 28.6 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU20696.1 - 2.1e-06 27.8 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OEU20696.1 - 0.02 14.6 0.1 0.057 13.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 OEU20696.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 OEU20696.1 - 0.096 12.8 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Synaptobrevin PF00957.21 OEU20697.1 - 2.3e-19 69.0 1.3 4.8e-19 67.9 1.3 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OEU20697.1 - 3.3e-10 39.9 0.6 6.5e-10 38.9 0.6 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain tRNA_deacylase PF04414.12 OEU20697.1 - 0.032 13.7 0.3 0.053 13.0 0.3 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase TMIE PF16038.5 OEU20697.1 - 1.1 9.1 8.5 0.14 12.0 1.5 2.6 2 1 0 2 2 2 0 TMIE protein Abhydrolase_6 PF12697.7 OEU20698.1 - 3.3e-06 27.8 2.2 4.2e-05 24.3 2.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OEU20698.1 - 0.0026 17.6 0.2 0.016 15.1 0.2 2.0 1 1 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 OEU20698.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OEU20698.1 - 0.017 15.0 0.1 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OEU20698.1 - 0.028 14.1 0.0 0.11 12.2 0.0 1.9 1 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU20698.1 - 0.18 11.0 0.1 3.6 6.8 0.1 2.3 1 1 0 1 1 1 0 Serine aminopeptidase, S33 RCC1 PF00415.18 OEU20699.1 - 9.8e-46 154.2 11.9 9.3e-11 42.2 0.5 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU20699.1 - 9.6e-32 108.1 37.8 8e-10 38.3 0.3 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Cnd1 PF12717.7 OEU20700.1 - 0.0001 22.4 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OEU20700.1 - 0.00015 21.8 2.6 0.19 12.1 0.1 2.9 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.23 OEU20700.1 - 0.00046 20.1 0.2 1.4 9.1 0.0 2.5 1 1 1 2 2 2 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 OEU20700.1 - 0.0023 18.5 0.0 0.0029 18.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 OEU20700.1 - 0.017 15.5 0.1 0.048 14.0 0.0 1.8 1 1 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.6 OEU20700.1 - 0.078 13.5 0.1 0.25 11.9 0.0 1.9 1 1 1 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.20 OEU20700.1 - 0.11 11.0 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region DUF3437 PF11919.8 OEU20700.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF2207 PF09972.9 OEU20702.1 - 0.0018 17.1 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) OPT PF03169.15 OEU20702.1 - 0.021 13.5 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Orf78 PF06024.12 OEU20702.1 - 0.025 14.9 0.3 0.025 14.9 0.3 2.9 4 0 0 4 4 4 0 Orf78 (ac78) DUF4711 PF15829.5 OEU20702.1 - 0.053 13.5 0.2 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) DUF1980 PF09323.10 OEU20702.1 - 0.26 11.2 1.3 15 5.5 0.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF4079 PF13301.6 OEU20703.1 - 1.2e-06 28.7 4.3 0.0084 16.3 0.5 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 OEU20703.1 - 0.00017 21.7 3.7 0.0024 18.0 0.2 2.4 1 1 0 2 2 2 2 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 OEU20703.1 - 0.012 15.2 5.2 0.035 13.7 5.2 1.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF998 PF06197.13 OEU20703.1 - 0.13 11.9 10.4 0.058 13.0 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Tetraspanin PF00335.20 OEU20703.1 - 0.64 9.7 3.8 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Tetraspanin family NAGLU PF05089.12 OEU20704.1 - 3.7e-79 266.1 2.9 1.4e-78 264.2 3.7 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OEU20704.1 - 9.8e-48 163.0 0.0 1.7e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OEU20704.1 - 2.8e-10 39.8 0.0 5.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PDZ_6 PF17820.1 OEU20705.1 - 6.6e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU20705.1 - 7.4e-05 23.0 0.2 0.00012 22.3 0.1 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU20705.1 - 0.0037 17.6 0.1 0.0051 17.1 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Abhydrolase_6 PF12697.7 OEU20707.1 - 0.057 14.0 0.0 0.079 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.10 OEU20707.1 - 0.091 11.8 0.0 0.36 9.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 OEU20707.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OEU20707.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA-synt_His PF13393.6 OEU20708.1 - 1.9e-35 122.7 0.0 7.5e-35 120.7 0.0 2.2 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OEU20708.1 - 4.3e-06 26.8 0.0 9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OEU20708.1 - 4.2e-05 23.6 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 OEU20708.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Methyltransf_11 PF08241.12 OEU20709.1 - 9.2e-10 39.1 0.0 2.2e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU20709.1 - 2.8e-08 33.7 0.0 7.1e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU20709.1 - 4e-07 30.6 0.1 7.5e-06 26.6 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU20709.1 - 0.0035 18.1 1.1 0.0056 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU20709.1 - 0.0086 15.4 0.1 0.022 14.1 0.1 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 OEU20709.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol_phi PF04931.13 OEU20709.1 - 0.21 9.6 9.4 0.31 9.1 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OEU20709.1 - 0.77 7.9 4.4 1 7.5 4.4 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 OEU20709.1 - 2 8.3 14.9 3.9 7.4 14.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_24 PF13578.6 OEU20710.1 - 1.9e-18 67.4 0.0 6e-18 65.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU20710.1 - 0.013 16.2 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OEU20710.1 - 0.023 15.4 0.0 0.053 14.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain GATase_6 PF13522.6 OEU20711.1 - 1.4e-13 51.1 0.0 5.3e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OEU20711.1 - 5.2e-12 45.8 0.0 1.4e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OEU20711.1 - 6.8e-09 35.4 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Kin17_mid PF10357.9 OEU20711.1 - 0.028 14.3 0.2 0.066 13.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Phos_pyr_kin PF08543.12 OEU20712.1 - 1.3e-78 263.8 0.0 1.5e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OEU20712.1 - 4.8e-06 26.1 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 OEU20712.1 - 0.00083 18.9 0.2 0.0015 18.1 0.2 1.4 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 OEU20712.1 - 0.0009 18.7 1.1 0.0077 15.6 0.0 2.4 3 0 0 3 3 3 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OEU20713.1 - 2.5e-36 124.7 0.0 3.1e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase DHO_dh PF01180.21 OEU20713.1 - 0.0018 17.5 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase IGPS PF00218.21 OEU20713.1 - 0.0086 15.3 0.0 0.014 14.6 0.0 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 OEU20713.1 - 0.048 12.8 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Glyoxal_oxid_N PF07250.11 OEU20714.1 - 0.039 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus NUDIX PF00293.28 OEU20715.1 - 5.9e-11 42.5 0.1 1.6e-10 41.1 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain Seipin PF06775.14 OEU20716.1 - 2.7e-25 89.6 1.6 5.2e-25 88.7 1.6 1.5 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PI3_PI4_kinase PF00454.27 OEU20717.1 - 9.2e-26 91.2 0.0 7.6e-25 88.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 OEU20718.1 - 2.8e-07 30.2 0.6 7.1e-07 28.9 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OEU20718.1 - 2.5e-05 24.6 0.1 0.00012 22.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OEU20718.1 - 0.0018 18.1 0.4 0.0059 16.4 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OEU20718.1 - 0.082 13.0 0.3 0.32 11.1 0.3 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain EF-hand_6 PF13405.6 OEU20719.1 - 0.00012 21.7 8.2 0.67 10.0 0.2 6.5 8 0 0 8 8 8 2 EF-hand domain EF-hand_7 PF13499.6 OEU20719.1 - 0.01 16.2 11.0 0.087 13.3 0.1 6.0 6 1 1 7 7 7 0 EF-hand domain pair EF-hand_1 PF00036.32 OEU20719.1 - 0.041 13.4 6.4 8.6 6.2 0.3 5.3 5 0 0 5 5 5 0 EF hand DUF4611 PF15387.6 OEU20719.1 - 3.2 8.0 6.5 7.4 6.9 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AA_kinase PF00696.28 OEU20721.1 - 2.8e-10 40.2 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 OEU20721.1 - 0.0014 18.8 0.1 0.0034 17.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU20721.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU20721.1 - 0.022 15.1 0.1 0.056 13.9 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase_3 PF13468.6 OEU20722.1 - 5.4e-21 75.5 0.0 7.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OEU20722.1 - 0.00011 22.4 0.0 0.00029 21.1 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Diphthamide_syn PF01866.17 OEU20723.1 - 0.29 10.6 5.5 3.9 6.8 0.2 2.5 2 0 0 2 2 2 0 Putative diphthamide synthesis protein SPX PF03105.19 OEU20726.1 - 1.1e-23 84.8 24.0 1.6e-15 57.9 8.0 3.0 2 1 1 3 3 3 2 SPX domain Ribosomal_L36e PF01158.18 OEU20726.1 - 3.6 7.9 6.3 2.7 8.3 0.9 3.3 5 0 0 5 5 5 0 Ribosomal protein L36e Macoilin PF09726.9 OEU20726.1 - 4.7 5.6 14.3 0.15 10.6 7.5 1.8 2 0 0 2 2 2 0 Macoilin family Zip PF02535.22 OEU20726.1 - 8.2 5.5 6.2 2.6 7.2 3.4 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter DHHC PF01529.20 OEU20727.1 - 1.4e-14 54.3 3.1 1.9e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.6 OEU20727.1 - 0.065 13.0 1.5 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Sec3_C_2 PF15278.6 OEU20728.1 - 0.0071 16.7 0.6 0.014 15.7 0.6 1.4 1 0 0 1 1 1 1 Sec3 exocyst complex subunit RRM_4 PF10598.9 OEU20728.1 - 0.052 13.9 0.3 0.1 12.9 0.3 1.5 1 0 0 1 1 1 0 RNA recognition motif of the spliceosomal PrP8 MRAP PF15183.6 OEU20728.1 - 0.37 10.8 2.3 0.79 9.7 2.3 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family HD-ZIP_N PF04618.12 OEU20729.1 - 0.11 13.0 0.2 0.15 12.6 0.2 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus zf-MYND PF01753.18 OEU20730.1 - 3.7e-11 42.9 13.0 3.7e-11 42.9 13.0 1.6 1 1 1 2 2 2 1 MYND finger zf-HIT PF04438.16 OEU20730.1 - 0.014 15.2 9.6 0.024 14.5 9.6 1.4 1 0 0 1 1 1 0 HIT zinc finger DUF2525 PF10733.9 OEU20730.1 - 0.062 13.6 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2525) Ecl1 PF12855.7 OEU20730.1 - 0.15 13.2 3.9 0.2 12.8 3.9 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 OEU20730.1 - 6.4 7.2 16.9 1.6 9.1 12.5 2.1 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Sulfotransfer_1 PF00685.27 OEU20731.1 - 3.4e-07 30.0 0.2 2e-06 27.5 0.2 2.0 1 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU20731.1 - 5.2e-07 30.3 1.4 1.2e-06 29.1 0.0 2.1 2 1 0 2 2 2 1 Sulfotransferase family Vps5 PF09325.10 OEU20732.1 - 1.6e-31 109.7 6.0 2.2e-31 109.3 6.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 OEU20732.1 - 1.9e-22 79.3 0.0 5.5e-22 77.9 0.0 1.8 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 OEU20732.1 - 0.00013 21.5 4.5 0.038 13.4 4.5 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Pil1 PF13805.6 OEU20732.1 - 0.0009 18.8 3.0 0.0021 17.6 2.6 1.7 1 1 1 2 2 2 1 Eisosome component PIL1 Arfaptin PF06456.13 OEU20732.1 - 0.0056 16.3 7.3 0.015 14.8 5.1 2.1 1 1 1 2 2 2 1 Arfaptin-like domain DUF948 PF06103.11 OEU20732.1 - 0.045 14.0 0.1 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 OEU20732.1 - 0.12 10.9 4.1 0.19 10.2 4.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4516 PF14990.6 OEU20733.1 - 0.01 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) RE_TaqI PF09573.10 OEU20733.1 - 0.096 12.5 2.4 0.14 11.9 2.4 1.3 1 0 0 1 1 1 0 TaqI restriction endonuclease DUF3144 PF11342.8 OEU20734.1 - 0.031 14.6 0.0 0.14 12.4 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) RCC1 PF00415.18 OEU20737.1 - 7e-33 113.0 12.9 2e-07 31.5 0.0 7.6 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU20737.1 - 3.7e-20 71.2 14.8 1.2e-10 40.9 0.8 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 OEU20738.1 - 4e-22 78.1 19.9 0.00053 20.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20738.1 - 3.1e-09 37.0 6.5 0.3 11.4 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OEU20738.1 - 0.013 14.9 1.8 0.12 11.7 0.9 2.7 1 1 1 2 2 2 0 WD40-like domain LPP PF04728.13 OEU20738.1 - 0.032 14.6 4.8 0.14 12.6 0.3 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper YabA PF06156.13 OEU20738.1 - 0.13 13.0 20.4 0.21 12.3 6.2 3.1 2 1 0 2 2 2 0 Initiation control protein YabA DUF2935 PF11155.8 OEU20738.1 - 0.36 11.2 10.3 1.6 9.1 4.5 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) TSC22 PF01166.18 OEU20738.1 - 0.46 10.8 8.2 9.2 6.7 1.8 3.2 1 1 1 2 2 2 0 TSC-22/dip/bun family ATG16 PF08614.11 OEU20738.1 - 0.58 10.4 32.1 0.12 12.5 24.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAM150 PF15129.6 OEU20738.1 - 1.3 9.2 9.0 0.67 10.1 6.2 2.0 1 1 0 1 1 1 0 FAM150 family ADIP PF11559.8 OEU20738.1 - 5.2 7.2 36.8 4.6 7.3 7.7 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ATP-synt_DE_N PF02823.16 OEU20739.1 - 5.7e-16 58.2 0.1 9.5e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_ab PF00006.25 OEU20740.1 - 1.9e-61 207.5 0.0 2.7e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OEU20740.1 - 7.1e-23 80.9 1.5 1.5e-22 79.9 1.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RnfC_N PF13375.6 OEU20740.1 - 0.015 15.2 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain AAA_19 PF13245.6 OEU20740.1 - 0.048 14.0 0.5 0.18 12.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OEU20740.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 OEU20740.1 - 0.096 11.9 0.5 0.2 10.8 0.2 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 OEU20740.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OEU20740.1 - 0.23 10.6 0.1 0.4 9.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mito_carr PF00153.27 OEU20742.1 - 1.2e-35 121.3 8.9 6.3e-14 51.7 0.9 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein VIT1 PF01988.19 OEU20743.1 - 3.2e-56 190.6 0.5 3.8e-56 190.4 0.5 1.1 1 0 0 1 1 1 1 VIT family Ribosomal_L6 PF00347.23 OEU20744.1 - 2.7e-25 88.8 3.2 8.2e-11 42.4 0.6 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 RelA_SpoT PF04607.17 OEU20746.1 - 9.4e-21 74.3 0.8 2.9e-20 72.7 0.8 1.8 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins Glu_synthase PF01645.17 OEU20748.1 - 1.2e-74 251.7 0.0 1.7e-74 251.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 OEU20748.1 - 0.0027 16.8 0.1 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase V-ATPase_C PF03223.15 OEU20750.1 - 6e-95 318.8 0.0 7.1e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PhaP_Bmeg PF09602.10 OEU20750.1 - 0.0082 16.1 1.2 0.022 14.7 0.0 2.1 3 0 0 3 3 3 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 2OG-FeII_Oxy_3 PF13640.6 OEU20751.1 - 7.2e-13 49.2 0.0 2.4e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-RING_2 PF13639.6 OEU20752.1 - 5.3e-12 45.9 9.6 5.3e-12 45.9 9.6 2.0 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU20752.1 - 1.1e-07 31.5 8.1 1.1e-07 31.5 8.1 1.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU20752.1 - 8e-07 28.7 4.4 8e-07 28.7 4.4 2.2 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 OEU20752.1 - 1.9e-05 24.5 7.3 1.9e-05 24.5 7.3 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 OEU20752.1 - 2.1e-05 24.7 12.4 2.1e-05 24.7 12.4 2.4 1 1 1 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU20752.1 - 4.2e-05 23.5 3.2 4.2e-05 23.5 3.2 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU20752.1 - 0.00027 20.7 9.7 0.00027 20.7 9.7 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU20752.1 - 0.00056 19.7 8.1 0.00056 19.7 8.1 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU20752.1 - 0.0007 19.4 14.4 0.0012 18.7 10.1 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU20752.1 - 0.0018 17.9 11.7 0.0022 17.6 10.7 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OEU20752.1 - 0.0071 16.1 5.8 0.02 14.7 5.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OEU20752.1 - 0.02 14.9 7.7 0.02 14.9 7.7 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 OEU20752.1 - 0.045 13.7 1.9 0.056 13.4 1.9 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain UPF0547 PF10571.9 OEU20752.1 - 0.23 11.6 8.5 0.81 9.8 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.6 OEU20752.1 - 0.42 10.6 12.5 0.64 10.0 5.6 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 OEU20752.1 - 0.57 10.4 14.9 2.7 8.2 10.7 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 OEU20752.1 - 1 9.3 13.0 0.07 13.0 7.0 2.2 2 2 0 2 2 2 0 PHD-finger PPR_2 PF13041.6 OEU20753.1 - 0.059 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family E1-E2_ATPase PF00122.20 OEU20754.1 - 9e-19 67.7 0.0 1.1e-16 60.8 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OEU20754.1 - 3.4e-14 53.6 0.6 1.1e-06 29.1 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OEU20754.1 - 0.0016 18.2 0.3 1.5 8.5 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OEU20754.1 - 0.0048 16.6 0.1 0.038 13.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OEU20754.1 - 0.017 15.2 0.0 0.056 13.5 0.0 1.9 1 0 0 1 1 1 0 Cation transport ATPase (P-type) RAMP4 PF06624.12 OEU20754.1 - 0.065 13.3 0.4 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 F-box-like PF12937.7 OEU20755.1 - 5.4e-07 29.4 0.3 1.5e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OEU20755.1 - 7.5e-05 22.5 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain COPI_assoc PF08507.10 OEU20756.1 - 0.13 12.3 13.8 0.31 11.1 13.8 1.6 1 1 0 1 1 1 0 COPI associated protein DUF2628 PF10947.8 OEU20756.1 - 1.5 9.2 6.5 5.9 7.3 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) DUF410 PF04190.13 OEU20758.1 - 1.7e-40 139.5 0.0 2.5e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Kinesin PF00225.23 OEU20759.1 - 1.4e-102 343.0 0.0 1.7e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU20759.1 - 3.6e-21 75.6 0.0 6.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Peptidase_S24 PF00717.23 OEU20760.1 - 0.00037 20.4 0.0 0.00078 19.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OEU20760.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 Transketolase_N PF00456.21 OEU20761.1 - 9.9e-108 360.0 2.3 1.6e-107 359.4 2.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OEU20761.1 - 5.7e-32 110.8 0.1 2.2e-31 108.9 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OEU20761.1 - 4.7e-08 33.0 0.0 1.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OEU20761.1 - 1.1e-05 24.8 0.5 0.00059 19.1 0.3 2.6 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OEU20761.1 - 0.00011 22.0 1.4 0.00096 19.0 0.4 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OEU20761.1 - 0.0014 17.7 0.2 0.0026 16.8 0.2 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4275 PF14101.6 OEU20761.1 - 0.0015 18.6 0.6 0.003 17.7 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4275) VPS9 PF02204.18 OEU20762.1 - 1.9e-14 53.7 0.2 3.4e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1269 PF06897.12 OEU20762.1 - 0.029 14.7 1.3 0.069 13.4 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) C1_1 PF00130.22 OEU20762.1 - 0.14 12.1 4.9 0.35 10.8 4.9 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 OEU20764.1 - 4.8e-09 36.7 1.8 0.00065 20.2 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU20764.1 - 1.3e-08 34.9 1.5 0.00069 19.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU20764.1 - 1.9e-07 31.5 2.6 0.00021 21.8 0.7 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU20764.1 - 1.7e-06 28.2 1.8 0.036 14.5 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OEU20764.1 - 0.00022 21.4 0.9 0.018 15.5 0.2 3.0 2 1 0 2 2 2 1 Ankyrin repeat Cytochrom_B559a PF00284.20 OEU20766.1 - 0.12 12.1 0.0 0.73 9.6 0.0 2.3 2 0 0 2 2 2 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit DUF1722 PF08349.11 OEU20768.1 - 0.0057 16.9 2.9 0.013 15.8 2.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1722) DUF674 PF05056.12 OEU20768.1 - 0.0094 14.9 0.1 0.011 14.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF674) V-SNARE_C PF12352.8 OEU20768.1 - 0.011 16.0 2.5 0.013 15.8 1.5 1.6 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OEU20768.1 - 0.011 15.6 1.1 0.014 15.3 1.1 1.2 1 0 0 1 1 1 0 Sec20 DUF2229 PF09989.9 OEU20768.1 - 0.26 10.9 1.7 0.32 10.6 1.7 1.0 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) CENP-H PF05837.12 OEU20768.1 - 0.79 10.2 7.1 1.4 9.4 7.1 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 OEU20768.1 - 4.7 7.9 8.6 7.9 7.2 2.3 2.3 1 1 1 2 2 2 0 SlyX ABC1 PF03109.16 OEU20769.1 - 3.8e-20 72.2 0.0 7.5e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OEU20769.1 - 0.017 15.1 0.0 0.032 14.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.11 OEU20769.1 - 0.077 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Cyclin_C PF02984.19 OEU20770.1 - 1.6e-11 44.4 0.0 2.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box-like PF12937.7 OEU20770.1 - 8.7e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Cyclin_N PF00134.23 OEU20770.1 - 1.1e-07 31.7 1.0 0.00014 21.6 0.1 2.5 1 1 1 2 2 2 2 Cyclin, N-terminal domain F-box PF00646.33 OEU20770.1 - 0.00035 20.4 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain PAS_12 PF18095.1 OEU20772.1 - 0.026 14.2 2.8 0.024 14.3 1.5 1.7 1 1 1 2 2 2 0 UPF0242 C-terminal PAS-like domain DUF5623 PF18536.1 OEU20772.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) SQS_PSY PF00494.19 OEU20774.1 - 9.5e-19 67.9 0.2 1.6e-18 67.2 0.2 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase Ni_hydr_CYTB PF01292.20 OEU20775.1 - 4.1e-15 55.9 0.1 4.9e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 CBM9_1 PF06452.11 OEU20776.1 - 8.2e-06 25.8 3.8 1.5e-05 25.0 3.8 1.6 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like Lyase_1 PF00206.20 OEU20777.1 - 1.5e-20 73.8 0.0 2.1e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OEU20777.1 - 4.3e-17 62.4 0.0 1.2e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus IBN_N PF03810.19 OEU20778.1 - 6.4e-12 45.2 1.1 2.1e-11 43.6 1.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain RIH_assoc PF08454.11 OEU20778.1 - 0.041 13.7 6.4 6.4 6.7 0.2 4.3 4 0 0 4 4 4 0 RyR and IP3R Homology associated CRM1_C PF08767.11 OEU20778.1 - 0.056 12.6 7.4 0.16 11.1 7.4 1.8 1 0 0 1 1 1 0 CRM1 C terminal GFA PF04828.14 OEU20779.1 - 3.4e-07 30.5 0.1 3.4e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme bZIP_1 PF00170.21 OEU20779.1 - 0.16 12.1 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor EamA PF00892.20 OEU20780.1 - 1.1e-07 32.0 21.9 2.9e-05 24.2 7.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OEU20780.1 - 0.00037 19.8 3.4 0.0006 19.1 3.4 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 OEU20780.1 - 0.0013 18.1 8.5 0.0021 17.5 4.0 2.2 1 1 1 2 2 2 1 Triose-phosphate Transporter family Autophagy_act_C PF03987.15 OEU20781.1 - 5.8e-14 52.4 0.1 1.2e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF3119 PF11317.8 OEU20782.1 - 1.8e-23 83.2 0.1 2.5e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) MgrB PF13998.6 OEU20782.1 - 0.0071 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 MgrB protein Rhomboid PF01694.22 OEU20783.1 - 3.1e-11 43.5 8.3 5.5e-11 42.7 8.3 1.4 1 0 0 1 1 1 1 Rhomboid family ComR_TPR PF18710.1 OEU20783.1 - 0.11 12.1 0.2 6.9 6.2 0.2 2.2 2 0 0 2 2 2 0 ComR tetratricopeptide TPR_12 PF13424.6 OEU20784.1 - 1e-27 96.2 0.0 8.7e-17 61.2 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU20784.1 - 1.4e-19 69.3 0.0 3e-07 30.1 0.0 4.8 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU20784.1 - 3.6e-16 58.2 1.7 0.00033 20.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20784.1 - 5e-15 54.4 2.1 0.00079 19.5 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU20784.1 - 1.4e-14 53.0 0.8 0.0014 18.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20784.1 - 2.9e-11 42.6 1.1 0.027 14.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU20784.1 - 5.7e-08 32.3 0.3 0.0012 18.5 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 OEU20784.1 - 1.3e-05 25.7 0.1 0.0039 17.8 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU20784.1 - 0.0018 18.9 0.2 17 6.5 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU20784.1 - 0.0085 15.5 0.0 0.97 8.7 0.0 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_21 PF09976.9 OEU20784.1 - 0.04 13.6 0.6 4.9 6.8 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 OEU20784.1 - 0.15 11.8 0.4 15 5.2 0.5 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Yip1 PF04893.17 OEU20785.1 - 2.1e-06 27.5 10.2 3.1e-06 27.0 10.2 1.4 1 0 0 1 1 1 1 Yip1 domain MFS_1 PF07690.16 OEU20786.1 - 4.6e-32 111.3 42.4 2.3e-24 86.0 20.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OEU20786.1 - 0.00054 18.5 2.7 0.0011 17.5 2.7 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector DBI_PRT PF02277.17 OEU20787.1 - 6.7e-94 314.8 7.8 8.7e-94 314.4 7.8 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase Colicin_V PF02674.16 OEU20788.1 - 0.087 12.8 1.0 0.16 12.0 1.0 1.5 1 0 0 1 1 1 0 Colicin V production protein CobU PF02283.16 OEU20789.1 - 3.4e-46 156.9 0.0 5e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4346 PF14251.6 OEU20789.1 - 6.3e-33 113.3 0.1 1.8e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4346) HSF_DNA-bind PF00447.17 OEU20792.1 - 3.1e-11 43.7 0.0 5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Rotamase PF00639.21 OEU20794.1 - 7.1e-19 68.6 0.0 9.8e-19 68.1 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OEU20794.1 - 1.1e-16 61.4 0.0 2e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OEU20794.1 - 0.0019 19.0 0.0 0.0024 18.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain NAD_Gly3P_dh_C PF07479.14 OEU20796.1 - 1.7e-45 154.8 0.1 2.8e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OEU20796.1 - 4e-40 137.4 0.0 6e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OEU20796.1 - 5.3e-05 23.7 0.0 0.00029 21.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OEU20796.1 - 0.0008 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OEU20796.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OEU20796.1 - 0.13 12.9 0.0 0.37 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YidD PF01809.18 OEU20797.1 - 6.6e-26 90.0 0.1 8.6e-26 89.6 0.1 1.2 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Na_H_Exchanger PF00999.21 OEU20798.1 - 1.6e-57 195.0 26.4 1.8e-57 194.9 26.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TylF PF05711.11 OEU20799.1 - 6.8e-10 38.7 0.1 5.5e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 Macrocin-O-methyltransferase (TylF) TPR_19 PF14559.6 OEU20799.1 - 0.00017 22.0 0.1 0.0098 16.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20799.1 - 0.00032 20.7 1.2 0.18 12.1 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20799.1 - 0.001 19.0 0.4 9.2 6.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU20799.1 - 0.0015 18.4 4.3 1 9.7 0.1 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat Methyltransf_24 PF13578.6 OEU20799.1 - 0.0047 17.9 0.0 0.015 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.6 OEU20799.1 - 0.019 14.7 0.1 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 OEU20799.1 - 0.041 14.2 4.5 2.6 8.4 0.1 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU20799.1 - 0.041 14.5 2.4 45 5.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OEU20799.1 - 0.051 13.6 0.5 14 5.8 0.1 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Methyltransf_17 PF12692.7 OEU20799.1 - 0.076 13.0 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase TPR_14 PF13428.6 OEU20799.1 - 0.092 13.6 5.0 12 7.1 0.0 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU20799.1 - 0.095 12.6 3.4 3.3 7.7 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 OEU20799.1 - 0.15 12.1 1.4 2.6 8.1 0.2 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) DRMBL PF07522.14 OEU20800.1 - 1.9e-18 66.7 0.6 1.9e-18 66.7 0.6 2.6 2 1 0 2 2 2 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 OEU20800.1 - 0.0019 18.1 0.1 0.005 16.7 0.1 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain UBA PF00627.31 OEU20800.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain CUE PF02845.16 OEU20800.1 - 0.088 12.5 0.1 0.32 10.8 0.1 2.0 1 0 0 1 1 1 0 CUE domain 7TMR-HDED PF07697.11 OEU20801.1 - 3 7.9 17.4 0.12 12.5 10.5 2.2 2 1 0 2 2 2 0 7TM-HD extracellular DUF3067 PF11267.8 OEU20802.1 - 2.2e-19 69.8 0.0 2.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) zf-RING_2 PF13639.6 OEU20803.1 - 4e-07 30.3 6.0 5.2e-06 26.7 6.0 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OEU20803.1 - 6.8e-07 29.0 1.7 1.5e-06 28.0 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU20803.1 - 3.9e-06 26.8 2.0 1.2e-05 25.2 2.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OEU20803.1 - 4.4e-05 23.7 3.1 0.00012 22.3 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OEU20803.1 - 0.00011 22.0 5.1 0.00035 20.4 0.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OEU20803.1 - 0.0013 18.6 3.5 0.0049 16.7 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU20803.1 - 0.0033 17.2 4.7 0.013 15.4 0.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU20803.1 - 0.0049 16.8 1.8 0.0049 16.8 1.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OEU20803.1 - 0.0063 16.6 0.3 0.0063 16.6 0.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OEU20803.1 - 0.011 15.5 7.0 0.052 13.3 0.6 3.3 3 0 0 3 3 3 0 RING-like zinc finger DUF5521 PF17659.1 OEU20803.1 - 0.044 11.6 6.4 0.065 11.1 6.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Zn_ribbon_17 PF17120.5 OEU20803.1 - 0.14 11.8 1.3 0.38 10.4 1.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2924 PF11149.8 OEU20803.1 - 0.8 10.1 7.7 0.13 12.6 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) Occludin_ELL PF07303.13 OEU20803.1 - 4.9 7.9 14.4 11 6.8 11.4 2.4 1 1 1 2 2 2 0 Occludin homology domain AAA PF00004.29 OEU20804.1 - 1.5e-11 44.8 0.0 2.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU20804.1 - 0.00033 21.1 0.0 0.00056 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU20804.1 - 0.00039 20.7 0.0 0.0019 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU20804.1 - 0.00041 20.1 0.0 0.0018 18.1 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OEU20804.1 - 0.0009 19.3 0.1 0.0018 18.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU20804.1 - 0.0023 17.3 0.2 0.032 13.6 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 OEU20804.1 - 0.0066 16.2 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 OEU20804.1 - 0.01 15.5 0.1 0.74 9.5 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OEU20804.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OEU20804.1 - 0.017 14.9 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU20804.1 - 0.02 15.4 0.0 0.029 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 OEU20804.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 OEU20804.1 - 0.037 14.5 0.0 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OEU20804.1 - 0.043 13.5 0.1 0.095 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OEU20804.1 - 0.051 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.6 OEU20804.1 - 0.052 13.7 0.0 0.27 11.3 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain KTI12 PF08433.10 OEU20804.1 - 0.052 13.0 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ResIII PF04851.15 OEU20804.1 - 0.14 12.2 0.0 0.46 10.5 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zot PF05707.12 OEU20804.1 - 0.21 11.2 0.2 4.1 7.0 0.2 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Ank_5 PF13857.6 OEU20805.1 - 0.00014 22.1 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA PF00004.29 OEU20805.1 - 0.00019 21.9 0.1 0.0005 20.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OEU20805.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OEU20805.1 - 0.013 15.5 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OEU20805.1 - 0.028 14.1 0.1 0.22 11.2 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 OEU20805.1 - 0.03 14.4 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Torsin Ank_4 PF13637.6 OEU20805.1 - 0.031 14.9 0.0 0.22 12.2 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU20805.1 - 0.064 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) AAA_18 PF13238.6 OEU20805.1 - 0.068 13.7 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 OEU20807.1 - 8.7e-11 42.6 0.0 1.8e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KTI12 PF08433.10 OEU20808.1 - 1.4e-40 139.5 3.2 5.6e-40 137.5 0.6 2.5 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 OEU20808.1 - 0.0041 17.7 0.0 0.015 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OEU20808.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU20808.1 - 0.022 14.9 0.1 0.059 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OEU20808.1 - 0.03 14.4 0.0 1.1 9.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OEU20808.1 - 0.031 14.5 0.1 0.1 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OEU20808.1 - 0.04 14.3 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 OEU20808.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SLX9 PF15341.6 OEU20808.1 - 2.3 8.6 14.3 0.46 10.9 1.0 3.7 4 0 0 4 4 4 0 Ribosome biogenesis protein SLX9 CBFD_NFYB_HMF PF00808.23 OEU20809.1 - 2.5e-27 94.9 0.1 5e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU20809.1 - 0.00031 21.1 0.2 0.001 19.4 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ATP-synt_ab_C PF00306.27 OEU20809.1 - 0.011 16.1 0.1 0.079 13.3 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain CENP-T_C PF15511.6 OEU20809.1 - 0.036 14.2 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RSN1_7TM PF02714.15 OEU20810.1 - 1.1e-22 80.7 26.6 2.3e-22 79.6 26.6 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OEU20810.1 - 7.4e-08 32.3 1.5 7.4e-08 32.3 1.5 4.1 5 0 0 5 5 5 2 Late exocytosis, associated with Golgi transport Glyco_transf_7C PF02709.14 OEU20810.1 - 0.097 12.3 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase Cys_rich_CPXG PF14255.6 OEU20810.1 - 0.099 12.6 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich CPXCG PK PF00224.21 OEU20811.1 - 1.9e-138 461.1 3.1 3.2e-138 460.4 3.1 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OEU20811.1 - 5.1e-19 68.6 0.1 1.7e-18 66.9 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OEU20811.1 - 0.00025 20.3 0.1 0.00061 19.0 0.1 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PcrB PF01884.17 OEU20811.1 - 0.048 13.1 0.2 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 PcrB family PrmA PF06325.13 OEU20811.1 - 0.049 13.0 0.8 0.24 10.7 0.2 2.3 2 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PIG-F PF06699.11 OEU20812.1 - 2.5e-05 24.5 6.3 8.1e-05 22.9 6.3 1.8 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F GDP_Man_Dehyd PF16363.5 OEU20813.1 - 7.2e-156 518.7 0.1 1e-155 518.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU20813.1 - 6.3e-72 241.9 0.1 9e-72 241.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OEU20813.1 - 0.00024 20.3 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OEU20813.1 - 0.001 18.3 0.0 0.0056 15.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OEU20813.1 - 0.0089 15.6 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family ORC2 PF04084.14 OEU20813.1 - 0.05 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 RRM_1 PF00076.22 OEU20814.1 - 0.018 14.9 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 OEU20815.1 - 2.3e-13 50.9 0.2 1.5e-12 48.2 0.2 2.1 1 1 0 1 1 1 1 SET domain AWS PF17907.1 OEU20815.1 - 0.015 15.3 10.4 0.015 15.3 10.4 2.1 2 1 0 2 2 2 0 AWS domain Mucin PF01456.17 OEU20816.1 - 6.4 6.8 10.5 0.89 9.5 5.5 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Abhydrolase_6 PF12697.7 OEU20817.1 - 4.7e-18 66.6 0.1 5.5e-18 66.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU20817.1 - 4.1e-16 59.0 0.0 5.7e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU20817.1 - 1.1e-10 41.6 0.1 0.00013 21.8 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 OEU20817.1 - 0.011 15.4 0.2 0.034 13.8 0.1 1.7 2 0 0 2 2 2 0 Putative esterase UPF0227 PF05728.12 OEU20817.1 - 0.028 14.4 0.1 0.4 10.6 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 OEU20817.1 - 0.064 13.0 0.0 2.5 7.9 0.1 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 OEU20817.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 OEU20817.1 - 0.18 11.7 0.0 14 5.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal HopJ PF08888.11 OEU20818.1 - 2.3e-36 124.3 0.0 4.1e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 HopJ type III effector protein Spermine_synth PF01564.17 OEU20819.1 - 9.1e-33 113.2 0.0 1.1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 OEU20819.1 - 0.015 16.0 0.0 0.028 15.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OEU20819.1 - 0.086 12.6 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain AdoMet_dc PF02675.15 OEU20820.1 - 3.6e-22 78.6 0.2 3.9e-22 78.5 0.2 1.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Pro_isomerase PF00160.21 OEU20821.1 - 3.8e-07 30.5 0.0 9.6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAM184 PF15665.5 OEU20822.1 - 0.73 9.6 41.4 0.17 11.6 15.2 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PKcGMP_CC PF16808.5 OEU20822.1 - 0.74 9.7 13.0 1.1 9.2 1.5 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tropomyosin_1 PF12718.7 OEU20822.1 - 0.77 9.9 53.4 0.3 11.2 27.1 2.9 1 1 1 2 2 2 0 Tropomyosin like DUF812 PF05667.11 OEU20822.1 - 1.1 8.0 43.7 6.4 5.5 43.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 OEU20822.1 - 5.5 6.3 51.3 1 8.7 35.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OEU20822.1 - 6.2 6.9 52.7 0.72 9.9 22.2 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 OEU20822.1 - 9.3 6.6 46.1 13 6.2 33.9 2.7 1 1 1 2 2 2 0 Fez1 FAM220 PF15487.6 OEU20823.1 - 0.11 12.1 4.8 0.17 11.5 4.8 1.3 1 0 0 1 1 1 0 FAM220 family CDC45 PF02724.14 OEU20823.1 - 0.97 7.6 7.9 1.9 6.7 7.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 OEU20823.1 - 1.1 7.9 5.3 1.2 7.7 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CaM-KIIN PF15170.6 OEU20823.1 - 1.5 9.1 4.8 9.1 6.5 0.1 3.1 2 1 1 3 3 3 0 Calcium/calmodulin-dependent protein kinase II inhibitor SRP-alpha_N PF04086.13 OEU20823.1 - 6 6.7 15.4 9.9 6.0 15.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Myb_DNA-bind_7 PF15963.5 OEU20825.1 - 3.1e-18 65.4 0.9 1.1e-17 63.7 0.9 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OEU20825.1 - 0.00034 20.7 0.1 0.00065 19.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDCD2_C PF04194.13 OEU20826.1 - 9.6e-24 84.4 1.4 3.5e-23 82.5 0.0 2.6 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain YdjO PF14169.6 OEU20826.1 - 0.092 12.5 2.3 22 4.9 0.3 3.3 3 0 0 3 3 3 0 Cold-inducible protein YdjO ASFV_p27 PF06556.11 OEU20827.1 - 0.018 15.1 0.4 0.018 15.1 0.4 1.9 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus CDC48_N PF02359.18 OEU20827.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain MgtE PF01769.16 OEU20828.1 - 2.8e-21 76.2 5.9 4.5e-21 75.5 5.9 1.3 1 0 0 1 1 1 1 Divalent cation transporter DnaJ PF00226.31 OEU20830.1 - 5.4e-18 64.9 0.9 6.6e-18 64.6 0.9 1.1 1 0 0 1 1 1 1 DnaJ domain ITAM_Cys-rich PF10538.9 OEU20830.1 - 0.39 10.5 1.8 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif DUF389 PF04087.14 OEU20831.1 - 4.8e-39 133.6 5.6 7.4e-39 133.0 5.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF389) PHO4 PF01384.20 OEU20831.1 - 1.5 7.8 9.5 0.49 9.4 2.1 2.2 1 1 1 2 2 2 0 Phosphate transporter family DUF389 PF04087.14 OEU20832.1 - 4.3e-40 137.0 8.7 7.2e-40 136.3 8.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF389) PHO4 PF01384.20 OEU20832.1 - 0.67 8.9 10.7 8.1 5.4 1.9 2.1 1 1 1 2 2 2 0 Phosphate transporter family DUF2070 PF09843.9 OEU20832.1 - 9.2 4.4 11.8 14 3.8 11.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SNF2_N PF00176.23 OEU20833.1 - 2.4e-59 200.8 0.0 3.9e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU20833.1 - 4.2e-19 68.9 0.0 9.8e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU20833.1 - 9.2e-08 32.3 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU20833.1 - 0.0087 15.3 0.0 0.031 13.4 0.0 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.6 OEU20833.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SWI2_SNF2 PF18766.1 OEU20833.1 - 0.031 14.0 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Bromodomain PF00439.25 OEU20834.1 - 3e-17 62.5 0.0 6.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF645 PF04875.12 OEU20835.1 - 0.023 14.7 0.2 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF645 Arm PF00514.23 OEU20836.1 - 0.029 14.4 3.8 10 6.4 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DOT1 PF08123.13 OEU20837.1 - 8.9e-09 35.2 0.1 5.3e-08 32.6 0.1 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 Pkinase PF00069.25 OEU20838.1 - 2.6e-18 66.3 0.0 2.9e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20838.1 - 2.3e-12 46.8 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pyr_redox_2 PF07992.14 OEU20839.1 - 5.4e-10 39.0 0.2 0.013 14.8 0.0 3.5 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU20839.1 - 9.1e-09 34.9 1.1 1.5e-07 30.9 0.1 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OEU20839.1 - 1.7e-05 24.9 0.2 0.14 12.2 0.1 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 OEU20839.1 - 0.0043 16.7 0.1 0.093 12.3 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OEU20839.1 - 0.043 14.4 0.0 1.3 9.6 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU20840.1 - 6.8e-25 88.4 0.0 1e-24 87.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU20840.1 - 0.00026 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU20840.1 - 0.0021 17.4 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU20840.1 - 0.22 10.5 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.32 OEU20842.1 - 0.00013 22.7 10.4 3 8.9 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2859 PF11072.8 OEU20842.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) zf-CCHC PF00098.23 OEU20843.1 - 2.3e-11 43.2 33.0 2.8e-08 33.5 1.3 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 OEU20843.1 - 2e-05 24.2 28.7 0.015 15.0 1.0 5.0 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 OEU20843.1 - 0.00033 20.4 33.0 0.0052 16.6 3.0 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.6 OEU20843.1 - 0.049 13.6 23.0 0.29 11.1 0.7 4.6 3 2 2 5 5 5 0 Zinc knuckle zf-C2H2_10 PF16588.5 OEU20843.1 - 4.4 7.1 28.7 0.31 10.8 1.6 4.9 5 0 0 5 5 5 0 C2H2 zinc-finger ENTH PF01417.20 OEU20844.1 - 4.9e-23 81.5 0.0 5.6e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 ENTH domain DUF2243 PF10002.9 OEU20844.1 - 0.0028 17.8 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) ANTH PF07651.16 OEU20844.1 - 0.014 14.4 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 ANTH domain Cyclin_N PF00134.23 OEU20847.1 - 1.2e-17 63.8 0.2 1.8e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU20847.1 - 1.5e-05 25.0 0.3 7.9e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain NFACT-R_1 PF05670.13 OEU20848.1 - 1.1e-29 103.2 0.2 5.2e-29 101.1 0.0 2.4 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 OEU20848.1 - 7.5e-27 93.3 0.0 7.5e-27 93.3 0.0 2.9 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 OEU20848.1 - 9.3e-22 77.4 15.3 1e-17 64.1 0.0 3.2 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) AP2 PF00847.20 OEU20848.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.4 3 0 0 3 3 3 0 AP2 domain V_ATPase_I PF01496.19 OEU20849.1 - 0.11 10.4 15.9 0.16 9.9 15.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 OEU20849.1 - 0.77 9.2 29.3 1.5 8.2 10.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF5082 PF16888.5 OEU20849.1 - 2.2 8.6 14.1 0.53 10.6 3.5 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) Cep57_MT_bd PF06657.13 OEU20849.1 - 5 7.6 13.1 0.51 10.8 0.2 3.8 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 OEU20849.1 - 5.4 7.2 24.1 0.069 13.4 7.9 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Exostosin PF03016.15 OEU20850.1 - 3.3e-18 65.9 0.0 5.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Prim_Zn_Ribbon PF08273.12 OEU20850.1 - 0.13 12.6 1.2 0.4 11.0 1.2 1.8 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase WD40 PF00400.32 OEU20853.1 - 5.7e-06 27.0 19.6 0.014 16.2 0.3 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat RNase_T PF00929.24 OEU20854.1 - 2.5e-06 28.1 0.0 4.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OEU20854.1 - 0.012 15.3 0.0 0.067 12.9 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease DUF4131 PF13567.6 OEU20855.1 - 1.2 8.8 4.0 3 7.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) COPI_assoc PF08507.10 OEU20855.1 - 5.3 7.1 12.3 0.44 10.6 4.8 2.9 1 1 1 2 2 2 0 COPI associated protein Cu-oxidase_2 PF07731.14 OEU20856.1 - 1.7e-37 128.2 13.1 2.3e-35 121.3 0.3 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OEU20856.1 - 3.6e-30 105.2 0.1 1.4e-29 103.3 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OEU20856.1 - 7.1e-29 100.2 1.6 7.1e-29 100.2 1.6 3.5 4 0 0 4 4 4 1 Multicopper oxidase BaxI_1 PF12811.7 OEU20857.1 - 0.18 11.3 1.7 0.26 10.8 1.7 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like mTERF PF02536.14 OEU20858.1 - 1.9e-14 53.3 3.0 6.9e-11 41.6 1.0 3.6 3 1 0 3 3 3 2 mTERF Sigma70_ner PF04546.13 OEU20858.1 - 0.044 13.7 0.4 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2541 PF10807.8 OEU20858.1 - 0.093 12.8 2.2 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) Pox_Ag35 PF03286.14 OEU20858.1 - 7.7 6.3 9.8 13 5.6 0.4 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ABC1 PF03109.16 OEU20859.1 - 2.9e-26 92.0 0.1 4.6e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 ABC1 family Vac14_Fab1_bd PF12755.7 OEU20862.1 - 1.1e-33 115.7 0.6 7.7e-31 106.6 0.2 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 OEU20862.1 - 1e-32 113.2 1.9 2.6e-32 111.9 1.9 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 OEU20862.1 - 0.00014 21.9 0.0 1.5 9.3 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat Atg14 PF10186.9 OEU20863.1 - 4.1e-08 32.7 6.9 1.5e-07 30.8 6.9 1.8 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 OEU20863.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Apg6 BARA domain Chorismate_bind PF00425.18 OEU20864.1 - 3.6e-62 210.3 0.0 5e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OEU20864.1 - 9.3e-37 126.6 0.0 2.1e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OEU20864.1 - 1.1e-11 45.1 0.0 1.5e-09 38.2 0.0 3.3 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OEU20864.1 - 6.2e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DUF3605 PF12239.8 OEU20865.1 - 6.8e-24 84.9 0.9 9.6e-24 84.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) bacHORMA_1 PF18138.1 OEU20865.1 - 0.0054 16.6 0.2 0.014 15.3 0.1 1.7 2 0 0 2 2 2 1 Bacterial HORMA domain family 1 Cwf_Cwc_15 PF04889.12 OEU20866.1 - 6.5 6.4 19.8 0.11 12.2 12.6 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1980 PF09323.10 OEU20867.1 - 0.038 13.9 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PPR_2 PF13041.6 OEU20868.1 - 1.6e-20 73.0 6.0 0.0004 20.5 0.0 8.3 7 3 1 8 8 8 5 PPR repeat family PPR_3 PF13812.6 OEU20868.1 - 3.3e-15 55.9 0.0 0.08 13.0 0.0 7.9 6 1 2 8 8 8 4 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU20868.1 - 1.5e-07 31.0 10.3 0.033 13.6 0.6 5.5 1 1 5 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OEU20868.1 - 3.3e-06 26.7 9.0 0.13 12.0 0.0 8.6 8 1 0 8 8 8 1 PPR repeat PPR PF01535.20 OEU20868.1 - 2.8e-05 24.1 19.6 0.0011 19.1 0.0 10.0 10 2 0 10 10 10 1 PPR repeat CREPT PF16566.5 OEU20868.1 - 0.05 13.8 1.6 1.5 9.0 0.5 3.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SesA PF17107.5 OEU20868.1 - 8.8 6.5 9.4 2.6 8.3 0.0 4.4 6 1 0 6 6 6 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Na_Ca_ex PF01699.24 OEU20869.1 - 2.5e-53 180.1 35.5 7.1e-30 104.0 14.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HAD_2 PF13419.6 OEU20871.1 - 2.4e-19 70.1 0.0 5.3e-19 69.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU20871.1 - 4e-14 53.4 0.1 7e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU20871.1 - 2.9e-08 33.6 0.0 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 OEU20871.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase MecA_N PF05223.11 OEU20871.1 - 0.063 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain NIF PF03031.18 OEU20872.1 - 3.6e-13 49.6 0.0 4.3e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OEU20872.1 - 0.0051 17.2 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Zip PF02535.22 OEU20873.1 - 2.3e-48 165.1 11.3 4.7e-34 118.1 5.2 3.2 1 1 2 3 3 3 2 ZIP Zinc transporter DUF4834 PF16118.5 OEU20873.1 - 0.013 16.5 0.0 2.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3487 PF11990.8 OEU20873.1 - 0.21 11.5 1.1 6.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF2358 PF10184.9 OEU20874.1 - 4.7e-09 36.5 2.2 3.3e-07 30.6 1.1 3.0 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2358) Peptidase_A21 PF03566.13 OEU20874.1 - 0.041 12.2 2.5 0.062 11.6 2.5 1.2 1 0 0 1 1 1 0 Peptidase family A21 RAP PF08373.10 OEU20875.1 - 3.2e-10 40.0 0.0 8.6e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 RAP domain Ribul_P_3_epim PF00834.19 OEU20876.1 - 6.5e-84 280.2 0.8 8e-84 280.0 0.8 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OEU20876.1 - 5.8e-07 29.4 0.1 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 OEU20876.1 - 0.0029 17.1 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 OEU20876.1 - 0.015 14.5 0.1 0.88 8.7 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 OEU20876.1 - 0.092 12.1 0.2 0.31 10.3 0.0 2.0 2 1 0 2 2 2 0 Thiamine monophosphate synthase Got1 PF04178.12 OEU20877.1 - 0.0022 18.4 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Histone PF00125.24 OEU20878.1 - 4.8e-20 72.2 0.6 5.9e-20 72.0 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OEU20878.1 - 0.00029 21.3 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 OEU20878.1 - 0.0025 17.9 0.2 0.003 17.6 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CBFD_NFYB_HMF PF00808.23 OEU20878.1 - 0.0049 17.1 1.2 0.0055 17.0 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 OEU20879.1 - 3.8e-20 71.3 2.2 7.1e-20 70.4 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OEU20879.1 - 1.1e-14 54.9 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OEU20879.1 - 0.00054 20.2 0.0 0.00071 19.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU20880.1 - 5.3e-54 182.1 1.0 5.9e-54 182.0 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OEU20880.1 - 0.00017 22.2 1.1 0.0002 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OEU20880.1 - 0.00076 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU20880.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OEU20880.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OEU20880.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 OEU20881.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU20881.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OEU20881.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OEU20881.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU20881.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OEU20881.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OEU20881.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OEU20881.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Abhydrolase_2 PF02230.16 OEU20883.1 - 9.5e-10 38.6 0.0 5.6e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 OEU20883.1 - 0.00017 21.2 0.0 0.00047 19.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 OEU20883.1 - 0.0026 17.3 0.0 2.5 7.5 0.0 3.0 2 1 1 3 3 3 2 Esterase PHB depolymerase Hydrolase_4 PF12146.8 OEU20883.1 - 0.0092 15.3 0.0 1.3 8.2 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DDE_1 PF03184.19 OEU20884.1 - 3.9e-16 59.2 0.0 3.6e-10 39.8 0.0 2.7 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 OEU20884.1 - 2.5e-10 40.5 2.7 3.8e-05 23.9 0.3 3.2 3 0 0 3 3 3 2 Transposase CENP-B_N PF04218.13 OEU20884.1 - 2.7e-05 23.7 0.2 0.0019 17.8 0.6 2.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 OEU20884.1 - 0.015 15.4 0.0 0.24 11.5 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 OEU20884.1 - 0.025 14.0 0.0 1.4 8.4 0.0 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 OEU20884.1 - 0.053 13.3 0.0 1.5 8.7 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 OEU20884.1 - 0.09 12.4 0.1 0.42 10.2 0.1 2.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding His_Phos_1 PF00300.22 OEU20885.1 - 1.5e-23 83.5 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GFO_IDH_MocA PF01408.22 OEU20886.1 - 1.9e-17 64.2 0.0 3.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OEU20886.1 - 9.6e-06 25.6 0.0 2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 OEU20886.1 - 6.8e-05 23.0 0.0 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_16 PF00722.21 OEU20887.1 - 4.2e-05 23.1 0.1 6.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PsbP PF01789.16 OEU20888.1 - 1.4e-21 77.3 0.0 2.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 PsbP MMS1_N PF10433.9 OEU20889.1 - 1.7e-74 251.3 0.2 2.8e-74 250.5 0.2 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OEU20889.1 - 1.1e-66 225.4 0.5 1.2e-65 221.9 0.1 2.4 3 0 0 3 3 3 1 CPSF A subunit region Peptidase_M20 PF01546.28 OEU20890.1 - 2.2e-33 115.7 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OEU20890.1 - 1.6e-07 31.2 0.0 3.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OEU20890.1 - 2e-05 24.4 0.0 0.00016 21.4 0.0 2.4 2 1 1 3 3 3 1 Peptidase family M28 RabGAP-TBC PF00566.18 OEU20892.1 - 9e-17 61.4 1.2 5.3e-16 58.9 1.2 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HSF_DNA-bind PF00447.17 OEU20893.1 - 6.1e-21 74.8 0.0 6.6e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding SecD-TM1 PF13721.6 OEU20895.1 - 0.28 11.7 4.7 0.29 11.6 4.2 1.4 1 1 0 1 1 1 0 SecD export protein N-terminal TM region Myb_DNA-binding PF00249.31 OEU20896.1 - 1.1e-16 60.8 2.9 1.2e-08 35.0 1.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU20896.1 - 3.6e-13 49.5 2.2 1.1e-07 32.0 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rab_bind PF16704.5 OEU20897.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Rab binding domain DUF3506 PF12014.8 OEU20899.1 - 1.7e-09 37.8 0.5 8.7e-06 25.8 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3506) DUF1690 PF07956.11 OEU20899.1 - 0.77 10.2 7.3 0.36 11.3 3.9 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Methyltransf_8 PF05148.15 OEU20900.1 - 2.2e-71 240.2 0.0 2.6e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OEU20900.1 - 3.7e-09 37.1 0.0 3.1e-08 34.1 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU20900.1 - 8.8e-07 28.8 0.0 0.0022 17.8 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OEU20900.1 - 2e-06 28.4 0.0 0.00018 22.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU20900.1 - 0.016 15.9 0.1 6.3 7.6 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OEU20900.1 - 0.04 13.3 0.0 0.16 11.3 0.0 1.8 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3506 PF12014.8 OEU20901.1 - 3.5e-17 62.7 0.0 4.6e-14 52.6 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) DEAD PF00270.29 OEU20902.1 - 4.4e-37 127.6 0.9 2.3e-36 125.2 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU20902.1 - 2.9e-26 92.0 0.0 1.7e-25 89.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU20902.1 - 8.7e-08 32.4 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OEU20902.1 - 0.025 14.9 0.1 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 OEU20902.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 OEU20902.1 - 0.045 14.0 1.1 0.28 11.5 1.1 2.3 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OEU20903.1 - 4.1e-22 76.4 3.3 9.6e-06 25.3 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 OEU20903.1 - 2.2e-21 75.2 0.1 0.00011 21.8 0.0 6.1 3 1 3 6 6 6 6 TPR repeat TPR_1 PF00515.28 OEU20903.1 - 1.2e-20 72.3 5.0 0.00013 21.6 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20903.1 - 1.3e-19 68.6 5.4 0.002 18.2 0.1 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 OEU20903.1 - 2.1e-18 65.3 4.9 0.0082 16.5 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OEU20903.1 - 3.1e-17 62.8 7.2 1.5e-06 28.6 0.7 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 OEU20903.1 - 3.6e-17 61.6 8.2 0.014 16.2 0.1 6.3 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 OEU20903.1 - 1.1e-12 48.4 1.4 0.00011 22.7 0.1 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OEU20903.1 - 9.6e-10 38.5 8.0 0.79 10.5 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 OEU20903.1 - 9.7e-10 38.5 1.5 7.3e-09 35.6 1.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 OEU20903.1 - 3e-09 36.9 7.9 1.5e-05 25.0 2.4 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20903.1 - 1.9e-06 27.5 1.2 1.3 9.2 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU20903.1 - 1.5e-05 25.1 11.4 0.4 11.0 0.4 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 OEU20903.1 - 0.0026 17.0 1.6 1.5 8.0 0.0 2.9 2 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU20903.1 - 0.0087 16.3 7.5 0.45 10.8 0.1 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 OEU20903.1 - 0.0094 15.4 0.1 28 4.2 0.0 3.6 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 OEU20903.1 - 0.033 14.0 13.1 9.8 6.2 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU20903.1 - 0.063 13.3 1.7 26 5.0 0.0 4.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat zf-CCHC PF00098.23 OEU20905.1 - 6.7e-06 25.9 0.4 1.1e-05 25.3 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OEU20905.1 - 0.0029 17.4 2.1 0.0052 16.6 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OEU20905.1 - 0.055 13.2 0.6 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle gag_pre-integrs PF13976.6 OEU20906.1 - 3.6e-09 36.4 0.7 1.2e-08 34.6 0.7 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain MgtE PF01769.16 OEU20907.1 - 1e-19 71.1 8.2 1e-19 71.1 8.2 1.4 2 0 0 2 2 2 1 Divalent cation transporter EMP70 PF02990.16 OEU20907.1 - 0.036 12.8 5.1 0.045 12.4 5.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF485 PF04341.12 OEU20907.1 - 0.26 11.2 5.2 0.19 11.7 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PHO4 PF01384.20 OEU20907.1 - 0.64 9.0 10.4 0.28 10.2 7.9 1.5 1 1 0 1 1 1 0 Phosphate transporter family PT PF04886.12 OEU20910.1 - 4.6e-11 42.1 47.9 0.00011 21.7 14.9 3.8 2 2 1 3 3 3 3 PT repeat Sulfotransfer_3 PF13469.6 OEU20911.1 - 0.0066 16.9 0.1 2 8.7 0.0 2.5 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 OEU20911.1 - 0.097 12.5 0.4 0.55 10.0 0.4 2.2 1 1 0 1 1 1 0 Sulfotransferase domain Radical_SAM PF04055.21 OEU20912.1 - 2e-21 77.1 0.0 4e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 OEU20912.1 - 1.4e-16 60.6 0.0 3.8e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Hydrolase PF00702.26 OEU20912.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 OEU20913.1 - 3.5e-34 116.2 5.6 1.3e-06 29.0 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20913.1 - 2.4e-13 50.2 0.1 0.0035 17.6 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OEU20913.1 - 0.011 15.7 0.5 0.11 12.4 0.3 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.6 OEU20913.1 - 0.021 14.4 0.0 0.056 13.0 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain BBS2_Mid PF14783.6 OEU20913.1 - 0.085 12.9 0.1 3.2 7.8 0.0 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region tRNA-synt_1e PF01406.19 OEU20914.1 - 2.3e-86 289.9 0.0 2.8e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OEU20914.1 - 8.2e-06 24.8 0.0 0.075 11.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) SBF_like PF13593.6 OEU20915.1 - 1.1e-73 248.3 17.6 1.3e-73 248.1 17.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 OEU20915.1 - 3.3e-09 36.7 8.1 8e-09 35.5 8.1 1.7 1 0 0 1 1 1 1 Sodium Bile acid symporter family PseudoU_synth_1 PF01416.20 OEU20916.1 - 6e-18 65.3 0.0 1.4e-11 44.8 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Metallophos PF00149.28 OEU20917.1 - 3.9e-34 118.9 0.4 5.3e-34 118.5 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OEU20917.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PAXNEB PF05625.11 OEU20918.1 - 1.1e-38 133.4 0.0 6.7e-38 130.8 0.0 2.3 1 1 0 1 1 1 1 PAXNEB protein RR_TM4-6 PF06459.12 OEU20918.1 - 0.054 13.3 4.3 0.087 12.6 4.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_16 PF00722.21 OEU20918.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 PGA2 PF07543.12 OEU20918.1 - 3.5 7.6 9.8 6.4 6.8 9.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Sec62 PF03839.16 OEU20918.1 - 4 6.9 5.3 6.4 6.2 5.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MMR1 PF08505.10 OEU20918.1 - 7.4 6.8 15.6 0.11 12.8 7.5 1.8 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DnaJ PF00226.31 OEU20919.1 - 3.7e-10 39.8 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Glyco_trans_1_2 PF13524.6 OEU20920.1 - 5.4e-13 49.1 0.5 1.3e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DRY_EERY PF09750.9 OEU20920.1 - 0.38 11.0 3.7 1 9.6 3.7 1.7 1 0 0 1 1 1 0 Alternative splicing regulator Abhydrolase_1 PF00561.20 OEU20921.1 - 1.5e-06 28.1 0.0 2.6e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU20921.1 - 0.0033 16.7 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 UBA PF00627.31 OEU20922.1 - 0.033 14.1 1.5 0.071 13.0 0.0 2.1 2 1 0 2 2 2 0 UBA/TS-N domain DUF454 PF04304.13 OEU20924.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF454) GRIM-19 PF06212.12 OEU20925.1 - 1.4e-17 63.9 0.2 1.6e-17 63.7 0.2 1.1 1 0 0 1 1 1 1 GRIM-19 protein TPR_12 PF13424.6 OEU20926.1 - 7.1e-25 87.1 20.4 0.00024 21.3 0.0 8.8 7 1 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 OEU20926.1 - 1.2e-10 40.7 34.5 0.0028 17.6 0.6 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU20926.1 - 3.1e-10 39.4 34.8 0.00042 20.0 0.6 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 OEU20926.1 - 7.5e-08 32.0 27.3 0.059 13.3 0.0 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20926.1 - 2.8e-05 23.8 20.8 0.0088 16.0 0.3 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20926.1 - 2.9e-05 23.9 32.2 0.4 11.0 0.6 9.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU20926.1 - 0.0043 17.8 17.1 0.39 11.7 0.1 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat Ribosomal_L27_C PF18471.1 OEU20926.1 - 0.0052 16.2 5.3 0.0052 16.2 5.3 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein C-terminal domain MIT PF04212.18 OEU20926.1 - 0.11 12.6 0.0 0.11 12.6 0.0 6.6 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain DUF2400 PF09674.10 OEU20926.1 - 0.33 10.9 2.8 0.86 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Syntaxin_2 PF14523.6 OEU20926.1 - 0.55 10.6 6.3 0.85 10.0 0.1 3.2 2 1 0 2 2 2 0 Syntaxin-like protein HAD_2 PF13419.6 OEU20927.1 - 1.5e-07 31.7 0.7 0.0018 18.4 0.0 3.5 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU20927.1 - 0.0085 16.4 0.0 0.14 12.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU20927.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Acid_PPase PF12689.7 OEU20927.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase GST_N_3 PF13417.6 OEU20928.1 - 3.1e-12 46.7 0.0 3.6e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU20928.1 - 1.2e-07 31.9 0.0 1.4e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU20928.1 - 0.0001 22.6 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HIT PF01230.23 OEU20929.1 - 8.1e-26 90.6 0.0 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OEU20929.1 - 7.9e-19 68.2 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.29 OEU20930.1 - 9.6e-44 149.2 0.5 1.5e-43 148.6 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU20930.1 - 7.2e-24 84.3 3.1 7.1e-23 81.1 0.5 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU20930.1 - 2.3e-07 31.0 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phage_integrase PF00589.22 OEU20930.1 - 0.0068 16.2 0.1 0.029 14.2 0.1 1.9 2 0 0 2 2 2 1 Phage integrase family AAA_19 PF13245.6 OEU20930.1 - 0.0079 16.5 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 OEU20930.1 - 0.017 14.4 0.2 0.033 13.5 0.2 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 OEU20930.1 - 0.034 13.3 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 OEU20930.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PALP PF00291.25 OEU20931.1 - 5.1e-62 209.9 0.1 5.8e-62 209.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aldo_ket_red PF00248.21 OEU20933.1 - 9.5e-27 93.9 0.0 1.6e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Galactosyl_T PF01762.21 OEU20934.1 - 1.5e-18 67.3 0.0 2.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OEU20934.1 - 0.002 17.6 0.1 0.0028 17.1 0.1 1.2 1 0 0 1 1 1 1 Fringe-like HA PF03457.14 OEU20936.1 - 6.7e-34 116.0 0.8 5e-19 68.4 0.2 2.4 2 0 0 2 2 2 2 Helicase associated domain IstB_IS21_ATP PF08483.11 OEU20936.1 - 0.12 12.3 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal TruD PF01142.18 OEU20937.1 - 1.3e-69 235.0 0.1 1.2e-66 225.3 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) ComJ PF11033.8 OEU20937.1 - 0.13 12.0 0.1 2.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Competence protein J (ComJ) Epimerase PF01370.21 OEU20938.1 - 8.8e-13 48.3 0.0 1.5e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OEU20938.1 - 2.4e-09 36.8 0.1 5.5e-06 25.7 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 OEU20938.1 - 1.6e-07 30.6 0.2 0.00057 19.0 0.1 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Sybindin PF04099.12 OEU20939.1 - 5.2e-15 55.6 0.2 9.2e-14 51.6 0.2 2.0 1 1 0 1 1 1 1 Sybindin-like family Pox_E8 PF03394.13 OEU20939.1 - 0.029 13.9 0.1 0.031 13.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus E8 protein Sedlin_N PF04628.13 OEU20939.1 - 0.045 13.9 0.5 0.047 13.8 0.5 1.3 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region YEATS PF03366.16 OEU20940.1 - 1.1e-27 95.8 0.5 2e-27 95.0 0.5 1.4 1 0 0 1 1 1 1 YEATS family Nucleoporin_FG2 PF15967.5 OEU20940.1 - 0.22 10.0 2.8 0.27 9.7 2.8 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region TMEM234 PF10639.9 OEU20942.1 - 0.00011 22.1 1.7 0.00023 21.2 0.1 2.1 2 0 0 2 2 2 1 Putative transmembrane family 234 UAA PF08449.11 OEU20942.1 - 0.00067 19.0 1.8 0.0011 18.2 1.6 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 OEU20942.1 - 0.0017 17.6 6.7 0.0017 17.6 6.7 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter Wzy_C PF04932.15 OEU20942.1 - 6.1 6.5 11.9 0.37 10.4 1.5 3.1 3 1 0 3 3 3 0 O-Antigen ligase TPR_2 PF07719.17 OEU20943.1 - 7.1e-11 41.4 1.1 0.00032 20.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU20943.1 - 6.1e-10 38.5 3.0 2e-05 24.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU20943.1 - 1.5e-09 37.3 8.3 0.00048 20.1 0.0 5.3 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU20943.1 - 3.4e-09 36.1 2.9 0.0042 17.0 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU20943.1 - 8e-09 35.3 4.5 0.0041 17.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU20943.1 - 7.4e-08 32.8 1.8 1.6e-05 25.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU20943.1 - 1.2e-07 32.0 0.1 0.00098 19.4 0.1 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU20943.1 - 3.9e-07 30.3 0.0 1.9 9.3 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU20943.1 - 7.4e-06 26.1 0.6 0.0051 17.0 0.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OEU20943.1 - 3.6e-05 23.4 1.8 0.031 14.0 0.0 3.7 4 0 0 4 4 4 2 TPR repeat DUF4919 PF16266.5 OEU20943.1 - 0.00011 22.2 0.5 0.0038 17.2 0.0 3.4 3 2 2 5 5 5 1 Domain of unknown function (DUF4919) TPR_14 PF13428.6 OEU20943.1 - 0.00023 21.7 0.0 0.041 14.7 0.0 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU20943.1 - 0.00046 20.0 0.2 0.22 11.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU20943.1 - 0.0011 19.0 0.0 0.0039 17.3 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 OEU20943.1 - 0.0015 18.8 0.0 4.6 7.6 0.0 3.3 2 2 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 OEU20943.1 - 0.0019 18.7 0.2 0.22 11.9 0.2 2.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 OEU20943.1 - 0.0027 17.7 0.1 0.015 15.4 0.0 2.3 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 OEU20943.1 - 0.0088 16.9 0.0 0.04 14.8 0.0 2.1 3 0 0 3 3 1 1 2OG-Fe(II) oxygenase superfamily TPR_16 PF13432.6 OEU20943.1 - 0.018 15.7 0.0 0.48 11.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Imm32 PF15566.6 OEU20943.1 - 0.039 13.8 0.1 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 32 TPR_3 PF07720.12 OEU20943.1 - 0.057 13.4 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF92 PF01940.16 OEU20944.1 - 4.5e-67 225.9 9.5 5.3e-67 225.7 9.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 SR-25 PF10500.9 OEU20945.1 - 0.29 10.7 15.4 0.094 12.3 9.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ThiF PF00899.21 OEU20946.1 - 3.5e-09 36.4 0.0 0.00039 19.9 0.0 2.1 1 1 1 2 2 2 2 ThiF family Dicty_REP PF05086.12 OEU20946.1 - 1.8 6.5 3.6 2.2 6.2 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AP3D1 PF06375.11 OEU20947.1 - 0.00061 20.1 2.1 0.00061 20.1 2.1 2.2 3 0 0 3 3 3 1 AP-3 complex subunit delta-1 EOS1 PF12326.8 OEU20947.1 - 0.051 13.5 2.4 0.1 12.5 2.4 1.4 1 0 0 1 1 1 0 N-glycosylation protein TFIIE-A_C PF11521.8 OEU20947.1 - 0.072 13.4 4.2 0.57 10.5 0.5 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Presenilin PF01080.17 OEU20947.1 - 0.17 10.7 1.5 0.22 10.2 1.5 1.3 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 OEU20947.1 - 0.41 11.6 3.5 5.7 8.0 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ALMT PF11744.8 OEU20947.1 - 1.1 8.1 3.9 1.7 7.4 3.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter NST1 PF13945.6 OEU20947.1 - 1.1 9.4 13.3 0.24 11.5 9.1 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator CNDH2_M PF16869.5 OEU20947.1 - 2.7 8.7 9.8 10 6.8 9.7 2.0 2 1 0 2 2 2 0 PF16858 DUF4820 PF16091.5 OEU20947.1 - 8.4 5.7 10.7 0.38 10.1 5.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF1180 PF06679.12 OEU20948.1 - 0.022 15.2 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Orf78 PF06024.12 OEU20948.1 - 0.036 14.4 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) RSN1_TM PF13967.6 OEU20948.1 - 0.056 13.2 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport EphA2_TM PF14575.6 OEU20948.1 - 0.068 14.1 0.0 0.1 13.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-LYAR PF08790.11 OEU20948.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger TMEM154 PF15102.6 OEU20948.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family bZIP_1 PF00170.21 OEU20949.1 - 0.00052 20.1 15.3 0.00052 20.1 15.3 3.0 3 0 0 3 3 3 1 bZIP transcription factor DUF3012 PF11216.8 OEU20949.1 - 0.32 11.1 3.0 1.8 8.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) PMSR PF01625.21 OEU20950.1 - 5.4e-34 117.6 3.3 1.4e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Peptide methionine sulfoxide reductase Ank_2 PF12796.7 OEU20951.1 - 1.2e-12 48.2 0.0 7e-09 36.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU20951.1 - 6e-12 45.8 1.2 7.4e-06 26.4 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU20951.1 - 4.6e-10 39.5 2.8 7.4e-06 26.1 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU20951.1 - 4e-09 36.0 0.0 1.4e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OEU20951.1 - 9.4e-08 32.2 0.0 3.9e-06 27.1 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Pkinase PF00069.25 OEU20952.1 - 5.2e-18 65.3 0.0 7.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20952.1 - 9.2e-15 54.6 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Secretin_N_2 PF07655.13 OEU20952.1 - 0.57 10.8 6.8 1.2 9.8 6.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain OCD_Mu_crystall PF02423.15 OEU20953.1 - 1.3e-46 159.0 0.4 1.4e-46 158.9 0.4 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OEU20953.1 - 1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OEU20953.1 - 0.028 14.6 0.0 0.043 14.0 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OEU20953.1 - 0.04 14.5 0.0 0.077 13.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-rbx1 PF12678.7 OEU20955.1 - 6.4e-05 23.2 1.8 6.4e-05 23.2 1.8 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU20955.1 - 9.4e-05 22.2 0.9 9.4e-05 22.2 0.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.18 OEU20955.1 - 0.00012 22.0 14.3 0.00012 22.0 14.3 2.4 2 0 0 2 2 2 1 MYND finger zf-RING_2 PF13639.6 OEU20955.1 - 0.00054 20.2 2.8 0.00054 20.2 2.8 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OEU20955.1 - 0.0009 19.1 3.3 0.0009 19.1 3.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU20955.1 - 0.0043 16.9 0.6 0.0043 16.9 0.6 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 PolC_DP2 PF03833.13 OEU20955.1 - 0.32 8.8 7.1 0.61 7.9 7.1 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_6 PF14835.6 OEU20955.1 - 1 9.3 5.5 0.25 11.3 0.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Pkinase PF00069.25 OEU20956.1 - 6e-17 61.9 0.0 7.2e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU20956.1 - 4.7e-13 49.0 0.0 6.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Proteasome PF00227.26 OEU20957.1 - 1.1e-18 67.4 0.0 5.1e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit PT PF04886.12 OEU20958.1 - 0.0086 15.6 7.6 0.0086 15.6 7.6 2.1 2 0 0 2 2 2 1 PT repeat HEAT_2 PF13646.6 OEU20959.1 - 2.3e-07 31.1 0.6 0.38 11.2 0.0 4.7 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.22 OEU20959.1 - 3.6e-05 23.7 6.1 0.027 14.7 0.1 5.4 5 0 0 5 5 5 2 HEAT repeat DUF3385 PF11865.8 OEU20959.1 - 0.0081 16.1 0.0 0.089 12.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OEU20959.1 - 0.035 14.7 0.0 0.23 12.1 0.0 2.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 OEU20959.1 - 0.044 13.8 0.2 0.55 10.4 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OEU20959.1 - 0.091 13.3 2.1 1 10.0 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat CLASP_N PF12348.8 OEU20959.1 - 0.19 11.3 10.0 0.27 10.8 0.0 4.5 5 0 0 5 5 5 0 CLASP N terminal DUF2718 PF10918.8 OEU20960.1 - 1.3 9.6 8.7 3.6 8.1 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2718) YCII PF03795.14 OEU20961.1 - 1.8e-06 28.3 0.0 2.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Abhydrolase_6 PF12697.7 OEU20962.1 - 1.7e-17 64.8 0.0 2.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU20962.1 - 6.8e-12 45.6 0.0 5.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU20962.1 - 3.9e-10 39.4 0.0 3.4e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 RVT_3 PF13456.6 OEU20964.1 - 3.4e-09 36.6 0.1 0.00034 20.4 0.0 3.5 2 1 0 2 2 2 2 Reverse transcriptase-like RRM_9 PF18444.1 OEU20964.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif FAA_hydrolase PF01557.18 OEU20965.1 - 5.2e-62 209.4 0.0 5.8e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family adh_short_C2 PF13561.6 OEU20966.1 - 1.4e-27 96.7 0.1 1.5e-27 96.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU20966.1 - 6e-20 71.5 0.2 7.3e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ELFV_dehydrog PF00208.21 OEU20966.1 - 0.007 16.1 0.1 0.0081 15.9 0.1 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MR_MLE_C PF13378.6 OEU20967.1 - 1.8e-54 184.6 0.0 2.5e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OEU20967.1 - 5e-11 42.8 0.0 8.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Lem_TRP PF08262.11 OEU20967.1 - 2.8 8.1 4.3 1.7 8.8 0.4 2.4 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide Dus PF01207.17 OEU20968.1 - 1e-49 169.3 0.0 1.2e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 OEU20968.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase BKACE PF05853.12 OEU20968.1 - 0.095 12.0 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 beta-keto acid cleavage enzyme Amino_oxidase PF01593.24 OEU20969.1 - 3.7e-22 79.2 0.0 3.4e-17 62.9 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU20969.1 - 8.6e-05 22.7 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OEU20969.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU20969.1 - 0.03 13.6 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU20969.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase CENP-B_dimeris PF09026.10 OEU20969.1 - 0.4 11.1 4.6 1.1 9.7 4.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Carboxyl_trans PF01039.22 OEU20970.1 - 1.3e-181 604.6 0.1 1.5e-181 604.4 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 OEU20970.1 - 0.0038 16.7 0.1 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Leader_CPA1 PF08252.11 OEU20970.1 - 0.5 9.8 2.4 1 8.8 2.4 1.4 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide bHLH-MYC_N PF14215.6 OEU20971.1 - 8.7e-06 26.1 1.1 1.6e-05 25.3 0.0 2.0 3 0 0 3 3 3 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.6 OEU20971.1 - 0.0043 17.4 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 GAF domain bHLH-MYC_N PF14215.6 OEU20972.1 - 7.6e-05 23.1 2.1 0.00069 19.9 0.0 2.7 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal FliP PF00813.20 OEU20972.1 - 2.2 8.1 10.3 5.6 6.8 10.3 1.6 1 0 0 1 1 1 0 FliP family PAT1 PF09770.9 OEU20972.1 - 3.7 5.7 26.5 6.2 5.0 26.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bZIP_1 PF00170.21 OEU20974.1 - 0.0024 17.9 0.5 0.0024 17.9 0.5 4.5 4 1 0 4 4 3 1 bZIP transcription factor BRE1 PF08647.11 OEU20974.1 - 0.025 14.6 5.0 0.025 14.6 5.0 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase SHE3 PF17078.5 OEU20974.1 - 0.083 12.6 23.8 0.22 11.2 23.9 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Scaffolding_pro PF11418.8 OEU20974.1 - 0.1 13.2 5.9 0.64 10.6 1.0 2.6 2 1 0 2 2 2 0 Phi29 scaffolding protein PRIMA1 PF16101.5 OEU20974.1 - 0.11 12.6 1.6 0.25 11.4 1.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SRP54 PF00448.22 OEU20974.1 - 0.49 10.0 4.0 23 4.5 4.0 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF5069 PF16798.5 OEU20974.1 - 0.76 10.0 6.7 0.31 11.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) HALZ PF02183.18 OEU20974.1 - 1.2 9.4 16.7 2.7 8.3 0.5 3.7 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.8 OEU20974.1 - 1.8 7.8 22.0 0.9 8.8 8.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 OEU20974.1 - 2.6 8.5 27.2 0.91 10.0 9.8 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 OEU20974.1 - 3.2 7.0 19.6 18 4.6 19.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 OEU20974.1 - 3.7 5.0 27.0 4.3 4.7 27.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YabA PF06156.13 OEU20974.1 - 5.2 7.8 23.8 0.75 10.5 6.8 3.1 1 1 2 3 3 3 0 Initiation control protein YabA Phasin PF05597.11 OEU20974.1 - 5.8 6.9 16.2 0.16 12.0 7.3 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GAS PF13851.6 OEU20974.1 - 8.2 5.7 30.0 3.4 7.0 20.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SUZ PF12752.7 OEU20975.1 - 3 8.7 6.1 0.62 10.9 1.3 2.3 2 0 0 2 2 2 0 SUZ domain Methyltransf_10 PF05971.12 OEU20976.1 - 1e-28 100.6 0.4 5.7e-27 94.8 0.4 2.8 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OEU20976.1 - 8.6e-06 25.4 0.1 0.023 14.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain RusA PF05866.11 OEU20976.1 - 0.12 12.9 0.6 0.33 11.5 0.6 1.7 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA PrmA PF06325.13 OEU20976.1 - 0.13 11.6 0.2 0.13 11.6 0.2 2.0 2 1 1 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) Folliculin PF11704.8 OEU20976.1 - 1.6 8.6 8.2 0.089 12.7 1.5 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 OEU20976.1 - 5.4 5.7 8.2 2.4e+02 0.3 8.2 2.3 1 1 0 1 1 1 0 Presenilin TFIIA PF03153.13 OEU20976.1 - 8.1 6.3 20.8 0.031 14.3 8.4 2.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Sedlin_N PF04628.13 OEU20977.1 - 7.2e-16 58.5 0.0 8.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF1995 PF09353.10 OEU20978.1 - 1.2e-23 84.2 0.0 1.8e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Ras PF00071.22 OEU20979.1 - 1.7e-58 196.8 0.1 2.2e-58 196.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU20979.1 - 4.3e-37 127.0 0.1 6e-37 126.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU20979.1 - 4.7e-16 58.7 0.0 5.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OEU20979.1 - 5.6e-06 25.9 0.1 7.3e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OEU20979.1 - 1.2e-05 25.0 0.0 3.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OEU20979.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OEU20979.1 - 0.00038 20.5 0.0 0.00064 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU20979.1 - 0.0019 18.1 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 OEU20979.1 - 0.055 13.0 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF89 PF01937.19 OEU20979.1 - 0.059 12.3 0.2 4.1 6.3 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF89 Dynamin_N PF00350.23 OEU20979.1 - 0.11 12.5 0.0 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Dynamin family PseudoU_synth_1 PF01416.20 OEU20980.1 - 9.9e-23 80.7 0.0 2.2e-18 66.7 0.0 3.0 3 0 0 3 3 3 2 tRNA pseudouridine synthase Presenilin PF01080.17 OEU20980.1 - 3.6 6.2 13.0 0.32 9.7 8.2 1.6 2 0 0 2 2 2 0 Presenilin DIOX_N PF14226.6 OEU20981.1 - 2.6e-15 57.2 0.4 6.5e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OEU20981.1 - 3.7e-15 56.2 0.1 8e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SUIM_assoc PF16619.5 OEU20981.1 - 0.0017 18.4 0.9 0.0041 17.1 0.9 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SRP_SPB PF02978.19 OEU20982.1 - 0.017 15.7 3.2 0.12 13.0 2.9 2.5 2 1 0 2 2 2 0 Signal peptide binding domain PHO4 PF01384.20 OEU20983.1 - 1.4e-105 353.1 33.0 1.7e-105 352.8 33.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family WD40 PF00400.32 OEU20984.1 - 1.3e-28 98.6 26.3 1.7e-07 31.8 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU20984.1 - 4e-10 39.9 0.6 0.0063 16.8 0.0 4.0 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Hus1 PF04005.12 OEU20985.1 - 5.2e-41 140.7 1.0 7.7e-41 140.1 1.0 1.2 1 0 0 1 1 1 1 Hus1-like protein RadC PF04002.15 OEU20985.1 - 0.079 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 RadC-like JAB domain DNA_pol_A_exo1 PF01612.20 OEU20986.1 - 1.4e-27 96.5 0.0 2.9e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 OEU20986.1 - 1.5e-06 28.0 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain CUT PF02376.15 OEU20986.1 - 0.029 14.5 0.8 0.44 10.7 0.1 2.8 3 0 0 3 3 3 0 CUT domain R3H PF01424.22 OEU20986.1 - 0.064 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 R3H domain ER_lumen_recept PF00810.18 OEU20987.1 - 1.6e-47 162.1 9.1 2.7e-47 161.3 9.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor TAL_FSA PF00923.19 OEU20988.1 - 3.9e-73 246.3 0.0 5.4e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Bromodomain PF00439.25 OEU20989.1 - 1.7e-12 47.2 0.1 3.9e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Bromodomain DUF2058 PF09831.9 OEU20989.1 - 0.00027 21.1 0.5 0.00093 19.4 0.5 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) SR-25 PF10500.9 OEU20989.1 - 6.1 6.4 26.4 0.083 12.5 6.9 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 OEU20989.1 - 6.4 5.4 9.1 12 4.5 9.1 1.4 1 0 0 1 1 1 0 Presenilin MORN PF02493.20 OEU20990.1 - 1.4e-35 119.0 54.0 3.8e-07 29.6 1.3 9.1 9 0 0 9 9 9 8 MORN repeat Tudor_2 PF18104.1 OEU20990.1 - 0.95 9.2 18.4 3.4 7.4 0.1 6.2 6 1 1 7 7 7 0 Jumonji domain-containing protein 2A Tudor domain MecA_N PF05223.11 OEU20992.1 - 0.052 13.8 2.7 0.091 13.0 0.1 2.6 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain TFIIA_gamma_N PF02268.16 OEU20992.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF179 PF02622.15 OEU20993.1 - 2.2e-18 66.7 0.0 7.2e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 Complex1_LYR PF05347.15 OEU20993.1 - 0.013 15.5 3.1 0.11 12.5 0.1 2.7 2 1 0 2 2 2 0 Complex 1 protein (LYR family) ApbA_C PF08546.11 OEU20993.1 - 0.067 13.4 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal TFIID_30kDa PF03540.13 OEU20994.1 - 5.7e-06 26.2 0.1 1.2e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit RhlB PF12300.8 OEU20994.1 - 0.0076 16.4 1.9 0.0076 16.4 1.9 1.9 2 0 0 2 2 2 1 ATP-dependent RNA helicase RhlB End_beta_propel PF12217.8 OEU20994.1 - 0.056 12.1 1.0 0.084 11.5 1.0 1.2 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase Histone_HNS PF00816.21 OEU20994.1 - 0.63 10.9 7.9 0.14 13.0 1.4 2.8 2 0 0 2 2 2 0 H-NS histone family DUF3439 PF11921.8 OEU20994.1 - 4.8 7.2 6.7 11 6.0 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Vps26 PF03643.15 OEU20995.1 - 3.7e-88 295.1 0.5 4.4e-88 294.8 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OEU20995.1 - 8.4e-05 22.7 0.5 1.7 8.7 0.1 3.7 3 1 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OEU20995.1 - 0.005 17.3 0.1 2.4 8.6 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PPR_1 PF12854.7 OEU20996.1 - 0.0012 18.5 5.8 1.5 8.6 0.0 4.9 4 1 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 OEU20996.1 - 0.0033 17.6 4.6 1.4 9.2 0.4 5.9 5 1 0 5 5 5 1 PPR repeat family RPM2 PF08579.11 OEU20996.1 - 0.016 15.6 0.0 6 7.3 0.0 3.0 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) SUIM_assoc PF16619.5 OEU20997.1 - 0.89 9.7 9.4 0.26 11.4 3.7 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF979 PF06166.12 OEU20998.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) SARAF PF06682.12 OEU20998.1 - 0.25 10.9 14.6 0.013 15.1 9.2 1.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4083 PF13314.6 OEU20998.1 - 0.3 11.1 2.4 0.7 9.9 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Polyketide_cyc PF03364.20 OEU20999.1 - 8.5e-16 58.3 0.0 1.2e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OEU20999.1 - 7.9e-05 23.0 0.0 0.00091 19.5 0.0 2.0 1 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport zf-RING_2 PF13639.6 OEU21000.1 - 3e-13 49.9 8.2 3e-13 49.9 8.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU21000.1 - 8.4e-10 38.2 6.1 1.9e-09 37.1 6.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU21000.1 - 7.4e-09 35.3 8.2 1.5e-08 34.3 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU21000.1 - 1.8e-07 30.9 7.5 1.8e-07 30.9 7.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU21000.1 - 4e-07 30.2 8.2 1.5e-06 28.4 8.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU21000.1 - 1e-06 28.7 3.7 1.1e-06 28.5 2.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU21000.1 - 1.4e-05 24.9 6.7 3.6e-05 23.6 6.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU21000.1 - 0.00075 19.3 5.4 0.00075 19.3 5.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU21000.1 - 0.00091 19.2 2.1 0.0022 18.0 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OEU21000.1 - 0.0017 18.2 6.2 0.0044 16.9 6.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OEU21000.1 - 0.015 14.9 6.0 0.015 14.9 6.0 1.8 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type Adeno_E1A PF02703.14 OEU21000.1 - 0.034 13.7 0.2 0.077 12.6 0.2 1.6 1 0 0 1 1 1 0 Early E1A protein PHD PF00628.29 OEU21000.1 - 0.15 12.0 6.5 0.44 10.5 6.5 1.9 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 OEU21000.1 - 4.4 7.5 11.2 0.74 10.0 6.7 2.1 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 OEU21000.1 - 6.4 7.0 13.3 0.069 13.3 4.3 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Pro-kuma_activ PF09286.11 OEU21001.1 - 0.022 15.0 0.7 0.037 14.3 0.7 1.3 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain DUF4492 PF14899.6 OEU21001.1 - 0.1 12.5 6.9 0.098 12.6 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) MFS_1 PF07690.16 OEU21001.1 - 0.21 10.5 1.1 0.32 9.9 1.1 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3914 PF13053.6 OEU21002.1 - 0.094 13.1 0.1 2.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) zf-CCHC PF00098.23 OEU21004.1 - 5.9e-18 64.0 22.2 2.2e-05 24.3 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 OEU21004.1 - 1.9e-05 24.5 17.1 0.1 12.6 2.5 4.1 1 1 3 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 OEU21004.1 - 0.00085 19.1 2.3 0.018 14.8 0.9 4.7 4 2 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 OEU21004.1 - 0.0064 16.2 19.4 0.3 10.9 0.2 4.1 4 0 0 4 4 4 4 Zinc knuckle Sar8_2 PF03058.14 OEU21004.1 - 1.3 9.6 7.3 0.97 10.0 0.7 2.8 2 1 1 3 3 3 0 Sar8.2 family TRAF6_Z2 PF18048.1 OEU21004.1 - 1.5 8.9 9.5 6.1 7.0 0.2 3.7 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 MFS_1 PF07690.16 OEU21005.1 - 3.3e-24 85.5 10.6 5e-16 58.6 7.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 OEU21006.1 - 4.8e-10 39.7 0.0 7.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU21006.1 - 8.4e-10 38.7 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU21006.1 - 9.8e-07 29.1 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU21006.1 - 4.6e-06 26.5 0.0 2.5e-05 24.2 0.0 2.1 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_8 PF13523.6 OEU21006.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAM91_N PF14647.6 OEU21006.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 FAM91 N-terminus PanZ PF12568.8 OEU21006.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DNA_methylase PF00145.17 OEU21007.1 - 0.0034 16.8 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase RTP PF02334.16 OEU21007.1 - 0.037 14.7 0.5 1.4 9.6 0.0 2.5 2 0 0 2 2 2 0 Replication terminator protein Vfa1 PF08432.10 OEU21007.1 - 7.5 6.8 14.2 58 4.0 0.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PAP_fibrillin PF04755.12 OEU21008.1 - 3.5e-05 23.8 0.0 7.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 PAP_fibrillin TAT_signal PF10518.9 OEU21008.1 - 0.041 13.7 1.0 0.084 12.7 1.0 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Chromate_transp PF02417.15 OEU21009.1 - 0.024 14.8 0.4 0.055 13.6 0.4 1.6 1 0 0 1 1 1 0 Chromate transporter RRM_1 PF00076.22 OEU21010.1 - 9.2e-17 60.6 0.0 1e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OEU21010.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L39 PF00832.20 OEU21011.1 - 3.1e-20 71.5 14.1 3.6e-20 71.3 14.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein GRDP-like PF07173.12 OEU21012.1 - 0.00014 22.6 0.4 0.00028 21.6 0.4 1.6 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Chloroa_b-bind PF00504.21 OEU21013.1 - 9.1e-33 114.1 0.1 1.1e-32 113.7 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATP19 PF11022.8 OEU21014.1 - 0.06 13.7 0.6 0.17 12.3 0.2 1.9 2 0 0 2 2 2 0 ATP synthase subunit K PTP_tm PF18861.1 OEU21014.1 - 0.24 11.4 2.3 0.38 10.7 2.1 1.5 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J She9_MDM33 PF05546.11 OEU21015.1 - 2.6e-24 86.1 4.9 2.6e-24 86.1 4.9 2.3 2 0 0 2 2 2 1 She9 / Mdm33 family PspB PF06667.12 OEU21015.1 - 0.51 10.4 1.9 18 5.5 0.0 3.0 2 0 0 2 2 2 0 Phage shock protein B MORN PF02493.20 OEU21016.1 - 7.6e-28 94.7 50.3 2.6e-06 27.0 6.8 7.8 7 1 0 7 7 7 7 MORN repeat betaPIX_CC PF16523.5 OEU21017.1 - 0.0011 18.7 0.4 0.0014 18.4 0.4 1.1 1 0 0 1 1 1 1 betaPIX coiled coil DnaJ_C PF01556.18 OEU21018.1 - 6.7e-38 130.1 0.0 8.8e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OEU21018.1 - 3.3e-20 72.0 0.1 5.7e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2857 PF11198.8 OEU21018.1 - 0.1 12.4 2.5 0.32 10.8 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) SGT1 PF07093.11 OEU21019.1 - 0.2 10.1 14.1 0.2 10.0 14.1 1.1 1 0 0 1 1 1 0 SGT1 protein DUF5523 PF17661.1 OEU21019.1 - 0.33 10.6 9.8 0.39 10.4 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SDA1 PF05285.12 OEU21019.1 - 2.6 7.4 32.5 3 7.2 32.5 1.0 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 OEU21019.1 - 3.2 6.7 15.3 3.5 6.5 15.3 1.0 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 OEU21019.1 - 4 7.7 8.5 5.3 7.3 8.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 OEU21019.1 - 5.6 5.1 25.5 5.6 5.1 25.5 1.0 1 0 0 1 1 1 0 CDC45-like protein ABC1 PF03109.16 OEU21020.1 - 3.2e-22 78.9 0.3 5.6e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 OEU21020.1 - 1.2e-06 28.1 0.0 0.0007 19.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 OEU21020.1 - 3e-06 27.3 0.1 1.2e-05 25.4 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 OEU21020.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.27 OEU21020.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase zf-MYND PF01753.18 OEU21021.1 - 6.1e-08 32.6 15.5 1.5e-07 31.3 15.6 1.7 1 1 0 1 1 1 1 MYND finger SAP PF02037.27 OEU21021.1 - 5.9e-05 22.7 0.0 0.013 15.2 0.0 2.9 2 1 0 2 2 2 2 SAP domain HeH PF12949.7 OEU21021.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain HEPN_Apea PF18739.1 OEU21021.1 - 0.016 15.6 0.3 0.094 13.2 0.0 2.4 2 1 0 2 2 2 0 Apea-like HEPN adh_short_C2 PF13561.6 OEU21022.1 - 7e-50 169.8 0.0 9.7e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU21022.1 - 4.7e-44 150.2 0.0 6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU21022.1 - 6e-08 32.8 0.3 6.7e-07 29.4 0.3 2.0 1 1 0 1 1 1 1 KR domain DnaJ PF00226.31 OEU21023.1 - 3.1e-12 46.4 0.4 9.8e-12 44.8 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain DUF3474 PF11960.8 OEU21023.1 - 0.77 9.9 2.9 3.3 7.9 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) V_ATPase_I PF01496.19 OEU21024.1 - 0.48 8.3 8.0 0.53 8.1 8.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSF_DNA-bind PF00447.17 OEU21027.1 - 6.2e-20 71.6 0.0 8.4e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5522 PF17653.1 OEU21028.1 - 6e-24 83.8 5.8 1.5e-23 82.5 5.8 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 OEU21028.1 - 2.9e-10 40.0 0.0 6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Peripla_BP_2 PF01497.18 OEU21028.1 - 6.7e-10 38.9 0.0 7.7e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 Periplasmic binding protein DUF3730 PF12530.8 OEU21028.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Radical_SAM PF04055.21 OEU21028.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily FeoB_associated PF12669.7 OEU21028.1 - 0.3 11.5 3.5 2.8 8.4 4.1 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein dsrm PF00035.26 OEU21029.1 - 0.00047 20.8 1.0 6.2 7.6 0.1 4.5 4 0 0 4 4 4 2 Double-stranded RNA binding motif FlaE PF07559.14 OEU21029.1 - 0.0061 17.1 0.4 10 6.7 0.0 4.7 4 0 0 4 4 4 1 Flagellar basal body protein FlaE Rib PF08428.10 OEU21029.1 - 0.67 10.0 4.3 1.2e+02 2.7 0.1 4.6 4 0 0 4 4 4 0 Rib/alpha-like repeat HSP70 PF00012.20 OEU21030.1 - 1.4e-22 79.6 1.1 9.4e-21 73.6 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein Ribosomal_L1 PF00687.21 OEU21030.1 - 0.0019 17.9 1.0 0.0077 16.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family FAM165 PF14981.6 OEU21030.1 - 1.7 8.5 0.0 1.7 8.5 0.0 2.6 2 1 1 3 3 3 0 FAM165 family Radical_SAM_C PF16199.5 OEU21031.1 - 2.9e-31 107.3 0.0 5.6e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OEU21031.1 - 1.4e-18 67.8 0.3 1e-17 65.0 0.1 2.3 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OEU21031.1 - 1.8e-11 44.3 0.0 5.3e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU21031.1 - 1.6e-05 24.9 0.0 3.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU21031.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU21031.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Lipase_3 PF01764.25 OEU21033.1 - 1.3e-16 60.7 0.0 2.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FAM176 PF14851.6 OEU21033.1 - 0.47 10.1 2.7 2.3 7.9 1.1 2.2 2 0 0 2 2 2 0 FAM176 family Dec-1 PF04624.14 OEU21033.1 - 1.3 9.0 9.6 2.8 7.9 9.6 1.6 1 0 0 1 1 1 0 Dec-1 repeat PBP1_TM PF14812.6 OEU21033.1 - 3 8.3 7.2 0.91 9.9 2.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Maf PF02545.14 OEU21034.1 - 3.1e-27 95.5 0.0 3.6e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Myb_DNA-bind_6 PF13921.6 OEU21035.1 - 8.8e-12 45.1 1.2 3.4e-07 30.4 0.1 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OEU21035.1 - 5.5e-10 39.3 0.2 1.5e-06 28.3 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain TauD PF02668.16 OEU21037.1 - 4.7e-28 98.7 0.0 8.1e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OEU21037.1 - 0.0015 17.8 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 CsiD ATP_synt_H PF05493.13 OEU21038.1 - 2.6e-20 72.6 1.2 2.9e-20 72.5 1.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Pox_A9 PF04835.12 OEU21038.1 - 0.046 13.9 2.5 0.88 9.8 0.2 2.1 2 0 0 2 2 2 0 A9 protein conserved region tRNA-synt_1g PF09334.11 OEU21039.1 - 5.1e-113 377.8 0.5 2.7e-67 227.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OEU21039.1 - 4.7e-30 104.4 2.0 9e-16 57.2 0.1 3.9 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OEU21039.1 - 5.8e-14 52.1 0.0 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 OEU21039.1 - 0.00011 22.2 0.1 0.00027 20.9 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF5331 PF17265.2 OEU21039.1 - 0.15 11.8 0.0 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5331) Choline_kinase PF01633.20 OEU21041.1 - 9.7e-46 156.0 0.0 1.5e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OEU21041.1 - 1.9e-06 28.0 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OEU21041.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Ammonium_transp PF00909.21 OEU21042.1 - 3.2e-15 55.8 0.1 2.1e-14 53.1 0.1 1.9 1 1 0 1 1 1 1 Ammonium Transporter Family SNase PF00565.17 OEU21043.1 - 1.3e-20 73.9 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue IQ PF00612.27 OEU21045.1 - 3.7e-58 187.9 286.2 0.0036 17.0 0.6 50.3 51 0 0 51 51 51 39 IQ calmodulin-binding motif KLRAQ PF10205.9 OEU21045.1 - 0.53 10.6 3.9 0.81 10.0 0.5 3.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein APG6 PF04111.12 OEU21046.1 - 1.6e-27 96.6 0.2 1.7e-19 70.4 0.1 3.2 2 1 0 2 2 2 2 Apg6 BARA domain Med9 PF07544.13 OEU21046.1 - 5.1 7.3 14.9 0.031 14.4 5.7 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Menin PF05053.13 OEU21046.1 - 9.7 4.4 13.6 0.51 8.6 4.7 2.3 2 0 0 2 2 2 0 Menin 2OG-FeII_Oxy PF03171.20 OEU21047.1 - 2.9e-07 30.9 0.7 0.0027 18.2 0.3 3.4 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily RPN2_C PF18004.1 OEU21047.1 - 0.015 15.2 2.5 0.015 15.2 2.5 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Mem_trans PF03547.18 OEU21047.1 - 1.6 7.0 3.5 7.3 4.9 0.4 2.6 3 0 0 3 3 3 0 Membrane transport protein DUF4820 PF16091.5 OEU21047.1 - 5.3 6.3 14.8 4.2 6.7 3.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4820) MAP17 PF15807.5 OEU21047.1 - 8.3 6.7 7.5 27 5.0 0.3 2.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 bPH_5 PF10882.8 OEU21048.1 - 0.12 12.5 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain Vps51 PF08700.11 OEU21049.1 - 1.2e-12 47.7 0.8 6.4e-12 45.4 0.1 2.8 2 1 1 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 OEU21049.1 - 1.4e-07 31.5 1.0 6.6e-07 29.3 0.1 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 Dor1 PF04124.12 OEU21049.1 - 1.6e-07 30.3 0.5 3.9e-07 29.1 0.5 1.6 1 0 0 1 1 1 1 Dor1-like family Thioredoxin PF00085.20 OEU21050.1 - 0.0024 17.8 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OEU21050.1 - 0.036 13.4 2.3 2.8 7.2 0.1 2.8 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family DUF3987 PF13148.6 OEU21050.1 - 0.085 11.8 1.1 1 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) LMBR1 PF04791.16 OEU21050.1 - 4.2 6.2 6.5 9.9 4.9 0.2 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein HMG_box PF00505.19 OEU21052.1 - 4.8e-29 100.6 12.7 3.5e-17 62.6 0.6 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU21052.1 - 1.6e-14 54.3 16.8 5.6e-09 36.5 4.7 3.3 2 1 0 2 2 2 2 HMG-box domain Ccdc124 PF06244.12 OEU21052.1 - 0.0025 18.3 12.6 0.18 12.3 0.0 3.5 2 1 0 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 Protamine_like PF06382.11 OEU21052.1 - 0.043 14.0 4.5 0.13 12.4 4.5 1.8 1 0 0 1 1 1 0 Protamine and protamine like TetR_C_19 PF17924.1 OEU21052.1 - 4.1 8.0 6.8 0.19 12.3 1.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3987 PF13148.6 OEU21052.1 - 9.9 5.1 10.5 4.2 6.3 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SET PF00856.28 OEU21053.1 - 3.8e-11 43.7 0.6 2.9e-10 40.8 0.6 2.0 1 1 0 1 1 1 1 SET domain HIT PF01230.23 OEU21055.1 - 3.6e-25 88.5 0.0 4.4e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OEU21055.1 - 1.2e-19 70.8 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Bac_DNA_binding PF00216.21 OEU21056.1 - 1.2e-28 99.1 0.2 2.3e-28 98.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial DNA-binding protein HU-HIG PF18291.1 OEU21056.1 - 8.6e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif AstA PF04958.12 OEU21056.1 - 0.023 13.3 0.1 0.03 12.9 0.1 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit HU-DNA_bdg PF14848.6 OEU21056.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 DNA-binding domain DUF2267 PF10025.9 OEU21056.1 - 0.059 13.6 0.1 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) HU-CCDC81_bac_2 PF18175.1 OEU21056.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_bac_1 PF18174.1 OEU21056.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 DUF445 PF04286.12 OEU21057.1 - 2.4e-19 70.4 0.0 1.2e-07 31.9 0.0 3.6 3 1 0 4 4 4 2 Protein of unknown function (DUF445) SbcCD_C PF13558.6 OEU21057.1 - 0.036 14.3 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TRAP-delta PF05404.12 OEU21058.1 - 0.021 14.3 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Pannexin_like PF12534.8 OEU21058.1 - 0.09 11.9 0.2 0.1 11.7 0.2 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Sulfotransfer_1 PF00685.27 OEU21059.1 - 5.7e-05 22.7 0.7 8.5e-05 22.2 0.7 1.3 1 1 0 1 1 1 1 Sulfotransferase domain RisS_PPD PF16524.5 OEU21060.1 - 0.0057 16.9 0.6 1.3 9.3 0.1 2.2 2 0 0 2 2 2 2 Periplasmic domain of Sensor histidine kinase RisS SET PF00856.28 OEU21061.1 - 6.3e-07 29.9 4.8 4.5e-06 27.2 0.0 3.8 2 2 0 2 2 2 1 SET domain Myb_DNA-binding PF00249.31 OEU21062.1 - 2.3e-06 27.7 0.4 1.5e-05 25.1 0.1 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU21062.1 - 0.0077 16.5 0.8 0.046 14.0 0.1 2.6 2 1 0 2 2 2 1 Myb-like DNA-binding domain DUF724 PF05266.14 OEU21062.1 - 2.2 8.0 8.3 3.5 7.4 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Gpi16 PF04113.14 OEU21063.1 - 2.2e-19 69.3 0.1 4.9e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DnaJ_CXXCXGXG PF00684.19 OEU21064.1 - 0.0062 16.9 4.1 0.0062 16.9 4.1 2.2 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 OEU21064.1 - 0.21 11.6 2.4 0.58 10.2 2.4 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Mito_carr PF00153.27 OEU21065.1 - 1.2e-58 195.1 1.4 4.2e-19 68.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.7 OEU21066.1 - 2.9e-10 41.1 0.0 6.2e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU21066.1 - 2.6e-09 36.7 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU21066.1 - 1.2e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OEU21066.1 - 1.6e-05 24.7 1.2 0.00013 21.8 0.2 2.3 2 1 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 OEU21066.1 - 0.0025 17.5 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 OEU21066.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 OEU21066.1 - 0.053 13.1 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 OEU21066.1 - 0.076 12.8 0.2 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OEU21066.1 - 0.082 11.8 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 OEU21066.1 - 0.086 12.7 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) RCC1 PF00415.18 OEU21067.1 - 2.6e-28 98.4 10.1 4e-12 46.6 0.1 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU21067.1 - 8.8e-24 82.7 4.5 1e-09 37.9 0.2 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OEU21067.1 - 0.013 15.2 0.0 7.5 6.2 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split CDC45 PF02724.14 OEU21068.1 - 0.0026 16.2 8.1 0.0029 16.0 8.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 OEU21068.1 - 0.0041 15.4 8.5 0.0047 15.2 8.5 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4484 PF14831.6 OEU21068.1 - 0.0047 17.0 3.6 0.0061 16.6 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SDA1 PF05285.12 OEU21068.1 - 0.012 15.0 9.3 0.014 14.9 9.3 1.2 1 0 0 1 1 1 0 SDA1 XAP5 PF04921.14 OEU21068.1 - 0.027 14.3 7.4 0.047 13.5 7.4 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sigma70_ner PF04546.13 OEU21068.1 - 0.037 13.9 7.6 0.049 13.5 7.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region HSP90 PF00183.18 OEU21068.1 - 0.041 12.8 6.8 0.053 12.4 6.8 1.2 1 0 0 1 1 1 0 Hsp90 protein Spt5_N PF11942.8 OEU21068.1 - 0.053 14.5 12.6 0.12 13.4 12.6 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CobT PF06213.12 OEU21068.1 - 0.079 12.3 8.5 0.11 11.9 8.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PTPRCAP PF15713.5 OEU21068.1 - 0.32 11.3 11.1 0.48 10.7 11.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 OEU21068.1 - 0.34 9.0 11.9 0.39 8.7 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OEU21068.1 - 0.38 10.0 12.1 0.59 9.4 12.1 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 OEU21068.1 - 1.8 7.7 6.2 3.2 6.9 6.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 OEU21068.1 - 1.8 7.0 7.7 2.1 6.8 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Roughex PF06020.11 OEU21068.1 - 3.7 6.6 11.9 2.9 6.9 10.9 1.3 1 1 0 1 1 1 0 Drosophila roughex protein UAA PF08449.11 OEU21069.1 - 1.1e-51 175.8 18.0 1.3e-51 175.6 18.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OEU21069.1 - 2.5e-05 24.5 23.9 0.00095 19.3 15.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OEU21069.1 - 0.0028 17.0 6.2 0.0028 17.0 6.2 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 OEU21069.1 - 0.01 14.8 13.3 0.024 13.6 1.2 2.3 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Syndecan PF01034.20 OEU21069.1 - 0.025 14.5 0.1 0.025 14.5 0.1 2.1 2 0 0 2 2 2 0 Syndecan domain Noc2 PF03715.13 OEU21072.1 - 1e-74 251.5 1.6 7.3e-74 248.7 0.6 2.1 2 0 0 2 2 2 2 Noc2p family Prefoldin_2 PF01920.20 OEU21073.1 - 7.1e-21 74.2 10.0 7.1e-21 74.2 10.0 1.8 1 1 1 2 2 2 1 Prefoldin subunit Acyl-CoA_dh_C PF12806.7 OEU21073.1 - 0.0065 16.6 4.6 0.12 12.5 0.0 2.1 1 1 1 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like DUF1664 PF07889.12 OEU21073.1 - 0.013 15.6 9.4 0.022 14.8 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1732 PF08340.11 OEU21073.1 - 0.016 15.2 5.3 1.6 8.8 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) ADIP PF11559.8 OEU21073.1 - 0.017 15.2 10.5 0.034 14.3 4.3 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YscO-like PF16789.5 OEU21073.1 - 0.024 14.6 4.1 0.024 14.6 4.1 1.9 1 1 1 2 2 2 0 YscO-like protein Prefoldin PF02996.17 OEU21073.1 - 0.045 13.7 9.1 0.15 11.9 9.1 2.0 1 1 0 1 1 1 0 Prefoldin subunit DMPK_coil PF08826.10 OEU21073.1 - 0.059 13.5 12.6 0.071 13.2 1.9 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like CCDC-167 PF15188.6 OEU21073.1 - 0.28 11.6 4.7 2.7 8.4 4.7 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 BLOC1_2 PF10046.9 OEU21073.1 - 0.44 10.9 10.3 0.18 12.2 2.5 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoLp-III PF07464.11 OEU21073.1 - 0.44 10.6 13.1 0.13 12.4 6.7 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Nas2_N PF18265.1 OEU21073.1 - 0.54 10.2 3.7 1.8 8.5 0.2 2.5 2 0 0 2 2 2 0 Nas2 N_terminal domain YojJ PF10372.9 OEU21073.1 - 0.75 9.9 6.3 2.4 8.3 0.5 3.0 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus FlaC_arch PF05377.11 OEU21073.1 - 0.77 10.2 9.8 1.6 9.2 0.2 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 OEU21073.1 - 0.95 10.0 11.1 1.4e+02 3.0 1.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Tup_N PF08581.10 OEU21073.1 - 1.2 9.4 7.2 5.2 7.5 1.2 2.7 2 1 0 2 2 2 0 Tup N-terminal OmpH PF03938.14 OEU21073.1 - 3.1 8.1 15.8 86 3.5 15.8 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Latarcin PF10279.9 OEU21073.1 - 8.1 6.9 7.3 1.9e+02 2.5 7.3 2.2 1 1 0 1 1 1 0 Latarcin precursor MMR_HSR1 PF01926.23 OEU21074.1 - 1.7e-16 60.3 0.2 3.1e-16 59.5 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU21074.1 - 5.6e-07 29.3 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OEU21074.1 - 4.5e-06 26.7 0.2 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OEU21074.1 - 8.8e-05 22.6 0.6 0.0045 17.1 0.6 2.3 1 1 0 1 1 1 1 Dynamin family Septin PF00735.18 OEU21074.1 - 0.00012 21.5 1.3 0.0042 16.4 1.3 2.6 1 1 0 1 1 1 1 Septin SRPRB PF09439.10 OEU21074.1 - 0.00073 19.0 0.1 0.76 9.2 0.1 2.5 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Roc PF08477.13 OEU21074.1 - 0.00095 19.4 0.0 0.045 14.0 0.0 2.3 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OEU21074.1 - 0.0024 17.6 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 OEU21074.1 - 0.0035 16.9 0.1 0.023 14.2 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 OEU21074.1 - 0.0045 17.5 0.8 0.0045 17.5 0.8 1.7 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 OEU21074.1 - 0.0089 16.5 0.5 0.015 15.8 0.5 1.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OEU21074.1 - 0.03 14.1 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 OEU21074.1 - 0.077 12.6 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 OEU21074.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AdoMet_dc PF02675.15 OEU21075.1 - 9.4e-23 80.5 0.1 1e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Spermine_synth PF01564.17 OEU21076.1 - 1.4e-33 115.9 0.7 1.7e-33 115.6 0.7 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 OEU21076.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 OEU21077.1 - 2.9e-38 131.4 0.0 8.6e-38 129.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU21077.1 - 4e-16 59.3 0.0 1.4e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU21077.1 - 4.1e-07 30.2 0.0 1.5e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU21077.1 - 0.047 14.0 1.8 30 4.9 0.0 3.9 3 2 1 4 4 4 0 AAA domain CRAL_TRIO PF00650.20 OEU21078.1 - 1.4e-32 112.6 0.0 1.7e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU21078.1 - 3.8e-09 36.8 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pro_isomerase PF00160.21 OEU21079.1 - 5.7e-07 29.9 0.0 2.4e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_6 PF13516.6 OEU21080.1 - 0.0052 16.7 2.7 14 6.1 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich repeat SUIM_assoc PF16619.5 OEU21080.1 - 0.082 13.0 9.0 0.46 10.6 1.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Orthopox_A49R PF06489.11 OEU21081.1 - 0.016 15.5 4.5 0.031 14.5 4.5 1.5 1 1 0 1 1 1 0 Orthopoxvirus A49R protein BTB_2 PF02214.22 OEU21082.1 - 0.027 14.8 1.1 0.059 13.7 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain TPR_8 PF13181.6 OEU21083.1 - 0.0071 16.5 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21083.1 - 0.026 14.6 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU21083.1 - 0.032 14.2 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21083.1 - 0.035 13.9 0.3 0.072 12.9 0.1 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5399 PF17377.2 OEU21084.1 - 0.47 10.3 3.6 4.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5399) Yippee-Mis18 PF03226.14 OEU21086.1 - 1.8e-13 50.6 0.7 3.1e-13 49.8 0.7 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OEU21086.1 - 0.025 14.8 1.0 0.042 14.1 1.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Hydrolase_4 PF12146.8 OEU21087.1 - 2.8e-15 56.2 0.1 1.3e-12 47.5 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OEU21087.1 - 3.1e-10 40.1 0.0 1.3e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OEU21087.1 - 9e-07 28.8 0.4 1.8e-05 24.5 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU21087.1 - 5e-06 26.1 0.0 0.00011 21.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OEU21087.1 - 7.5e-05 23.4 0.0 0.00011 22.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OEU21087.1 - 8.1e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 OEU21087.1 - 0.00024 19.9 0.0 0.00033 19.4 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.12 OEU21087.1 - 0.00098 17.9 0.0 0.39 9.3 0.0 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.20 OEU21087.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 2 0 0 2 2 2 0 Putative esterase 2-oxoacid_dh PF00198.23 OEU21088.1 - 5.7e-69 232.1 0.0 7.5e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OEU21088.1 - 2.5e-14 52.9 0.1 2.5e-13 49.6 0.0 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 OEU21088.1 - 2.2e-11 43.9 0.1 6.1e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OEU21088.1 - 0.064 13.1 0.0 9.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like Chloroa_b-bind PF00504.21 OEU21089.1 - 2.3e-27 96.5 0.5 2.8e-27 96.2 0.5 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Vta1 PF04652.16 OEU21090.1 - 1.6e-34 119.0 1.3 3.2e-34 118.0 0.1 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OEU21090.1 - 0.0021 17.7 2.5 0.0037 16.9 2.5 1.4 1 0 0 1 1 1 1 Vta1 C-terminal domain Mucin PF01456.17 OEU21091.1 - 0.044 13.8 5.6 0.088 12.8 5.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MAGE_N PF12440.8 OEU21091.1 - 7.4 7.3 11.7 2.1 9.1 2.7 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal PT PF04886.12 OEU21092.1 - 3.1 7.4 27.3 20 4.8 27.3 2.4 1 1 0 1 1 1 0 PT repeat Acid_PPase PF12689.7 OEU21094.1 - 0.00086 19.2 2.5 0.007 16.2 0.8 2.2 2 0 0 2 2 2 1 Acid Phosphatase CbiA PF01656.23 OEU21094.1 - 0.043 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4149 PF13664.6 OEU21094.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Peptidase_M14 PF00246.24 OEU21095.1 - 2.7e-22 79.9 0.0 3.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 OEU21095.1 - 0.0042 16.2 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family CAS_CSE1 PF03378.15 OEU21096.1 - 3.2e-117 391.8 0.3 3.2e-117 391.8 0.3 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OEU21096.1 - 7.5e-112 373.8 1.2 1.5e-111 372.9 1.2 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OEU21096.1 - 1.9e-12 46.9 0.0 5.6e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 OEU21096.1 - 0.0012 18.7 0.5 0.76 9.7 0.0 4.1 4 0 0 4 4 4 1 UME (NUC010) domain Xpo1 PF08389.12 OEU21096.1 - 0.002 18.2 1.8 0.015 15.4 0.0 3.5 3 1 1 4 4 4 1 Exportin 1-like protein RraA-like PF03737.15 OEU21098.1 - 6.4e-26 91.3 2.1 1.1e-14 54.8 0.0 2.1 2 0 0 2 2 2 2 Aldolase/RraA Cyclin_N PF00134.23 OEU21099.1 - 6.3e-05 22.7 4.4 0.014 15.1 4.4 2.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU21099.1 - 0.0035 17.4 0.2 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Neur_chan_memb PF02932.16 OEU21099.1 - 1.6 8.7 12.8 6.8 6.7 1.4 2.3 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3439 PF11921.8 OEU21099.1 - 1.9 8.4 10.3 0.16 11.9 4.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) V_ATPase_I PF01496.19 OEU21100.1 - 1.2e-264 880.2 8.5 5.9e-262 871.3 8.5 2.8 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family ABC2_membrane PF01061.24 OEU21101.1 - 4e-53 180.0 55.7 3e-34 118.3 24.4 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OEU21101.1 - 9.2e-47 159.0 0.0 1.8e-22 80.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OEU21101.1 - 1.4e-08 34.3 0.1 0.0061 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OEU21101.1 - 2e-08 34.8 0.0 0.0049 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OEU21101.1 - 8.7e-08 32.3 5.2 0.057 13.2 0.1 4.4 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU21101.1 - 4e-07 30.1 0.1 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 OEU21101.1 - 6.3e-07 28.8 12.5 6.3e-07 28.8 12.5 4.2 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 OEU21101.1 - 2.9e-06 27.6 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OEU21101.1 - 4e-06 27.5 6.7 0.018 15.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 OEU21101.1 - 7.5e-06 25.5 0.4 0.25 10.7 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 OEU21101.1 - 1.3e-05 25.6 0.1 0.026 15.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OEU21101.1 - 3.7e-05 23.7 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 OEU21101.1 - 0.00021 20.9 0.1 0.11 12.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OEU21101.1 - 0.00022 21.8 0.0 0.12 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OEU21101.1 - 0.00038 20.2 0.3 0.76 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU21101.1 - 0.00038 20.8 0.0 0.23 11.9 0.0 3.0 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 OEU21101.1 - 0.0012 18.9 0.1 0.45 10.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 OEU21101.1 - 0.0012 18.6 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 OEU21101.1 - 0.0013 18.5 0.6 1.7 8.3 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 OEU21101.1 - 0.011 16.1 0.3 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OEU21101.1 - 0.011 15.7 0.1 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OEU21101.1 - 0.013 15.5 0.3 0.67 9.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OEU21101.1 - 0.015 15.2 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 OEU21101.1 - 0.015 15.5 0.0 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 OEU21101.1 - 0.016 14.5 0.5 0.73 9.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 OEU21101.1 - 0.023 14.6 2.0 0.11 12.4 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OEU21101.1 - 0.024 14.2 0.1 8.7 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 OEU21101.1 - 0.024 14.2 0.1 5.3 6.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OEU21101.1 - 0.025 14.8 0.0 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OEU21101.1 - 0.041 13.8 0.1 10 6.0 0.0 3.1 4 0 0 4 4 3 0 NTPase RcsD_ABL PF16359.5 OEU21101.1 - 0.048 13.8 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 RcsD-ABL domain AAA_28 PF13521.6 OEU21101.1 - 0.1 12.8 0.1 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OEU21101.1 - 0.12 12.2 0.2 14 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATPase PF06745.13 OEU21101.1 - 0.15 11.4 0.3 17 4.6 0.0 2.9 3 0 0 3 3 3 0 KaiC ResIII PF04851.15 OEU21101.1 - 0.17 11.9 0.4 1 9.3 0.0 2.4 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OEU21101.1 - 0.23 10.7 3.8 2.3 7.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 OEU21101.1 - 1.3 9.0 4.9 11 6.0 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain NAM-associated PF14303.6 OEU21101.1 - 4.4 8.0 10.4 9.1 7.0 10.4 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF755 PF05501.11 OEU21102.1 - 0.06 13.6 8.7 0.052 13.8 5.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Herpes_UL79 PF03049.14 OEU21102.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 UL79 family FAST_2 PF08368.12 OEU21102.1 - 0.32 11.8 5.9 41 5.1 0.0 3.7 2 1 1 4 4 4 0 FAST kinase-like protein, subdomain 2 Ank_2 PF12796.7 OEU21103.1 - 3e-09 37.3 0.0 2.5e-07 31.2 0.0 2.5 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OEU21103.1 - 7.8e-06 25.9 0.0 0.86 10.4 0.0 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 OEU21103.1 - 9.7e-06 26.0 0.0 0.0095 16.5 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OEU21103.1 - 0.019 15.3 0.0 1 9.7 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 OEU21103.1 - 0.08 13.4 0.0 3.8 8.1 0.0 3.2 3 1 0 3 3 3 0 Ankyrin repeat Glyco_transf_4 PF13439.6 OEU21103.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 FAM167 PF11652.8 OEU21103.1 - 0.16 12.4 0.7 0.54 10.8 0.1 1.9 2 0 0 2 2 2 0 FAM167 PXA PF02194.15 OEU21103.1 - 4 7.4 7.7 6.4 6.7 1.5 2.5 2 1 0 2 2 2 0 PXA domain LOR PF04525.12 OEU21104.1 - 5.4e-09 35.9 0.2 9.4e-09 35.1 0.2 1.3 1 0 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 OEU21104.1 - 0.0083 15.5 0.1 0.49 9.7 0.1 2.2 1 1 1 2 2 2 2 Scramblase Auxin_canalis PF05703.11 OEU21104.1 - 0.16 11.9 0.5 0.25 11.2 0.5 1.2 1 0 0 1 1 1 0 Auxin canalisation Dynamin_M PF01031.20 OEU21105.1 - 4.4e-97 324.7 0.0 9.3e-97 323.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OEU21105.1 - 1.7e-53 181.2 0.1 4.8e-53 179.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OEU21105.1 - 6e-29 100.0 2.4 1.3e-28 99.0 2.4 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OEU21105.1 - 7.4e-05 22.8 0.2 0.00044 20.3 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ArfGap PF01412.18 OEU21106.1 - 7.7e-31 106.6 0.2 1.3e-30 105.9 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CDK2AP PF09806.9 OEU21106.1 - 0.42 10.7 2.9 1.8 8.6 2.9 2.0 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Nop25 PF09805.9 OEU21107.1 - 7.6e-06 26.4 31.6 7.6e-06 26.4 31.6 2.9 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Astro_capsid_N PF03115.14 OEU21107.1 - 0.24 10.0 3.1 0.53 8.9 3.1 1.6 1 0 0 1 1 1 0 Astrovirus capsid protein precursor V_ATPase_I PF01496.19 OEU21107.1 - 6.5 4.5 8.3 8.1 4.2 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PP2C PF00481.21 OEU21109.1 - 4.4e-23 82.2 0.3 3.5e-22 79.3 0.3 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU21109.1 - 2.6e-08 34.0 0.0 3.6e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OEU21109.1 - 1.2e-06 28.3 0.4 0.0037 16.9 0.2 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Peptidase_M14 PF00246.24 OEU21110.1 - 1.2e-10 41.6 2.4 5.9e-09 36.1 0.4 2.7 2 1 1 3 3 3 2 Zinc carboxypeptidase DUF4668 PF15701.5 OEU21110.1 - 0.069 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) TMEM52 PF14979.6 OEU21110.1 - 5.1 7.0 5.4 38 4.2 5.7 2.1 1 1 1 2 2 2 0 Transmembrane 52 BSP PF04450.12 OEU21113.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase of plants and bacteria DUF1924 PF09086.11 OEU21114.1 - 0.92 9.9 0.0 0.92 9.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) Xan_ur_permease PF00860.20 OEU21115.1 - 1.8e-31 109.2 28.3 1.2e-21 76.9 13.8 2.9 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.20 OEU21115.1 - 0.00035 19.5 3.3 0.00035 19.5 3.3 3.2 2 1 1 3 3 3 1 Sulfate permease family DUF5464 PF17552.2 OEU21115.1 - 0.0072 16.6 2.5 0.021 15.1 0.0 3.0 3 1 1 4 4 4 1 Family of unknown function (DUF5464) TPR_12 PF13424.6 OEU21116.1 - 2.1e-29 101.6 0.1 1e-09 38.5 0.3 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21116.1 - 4.2e-18 64.3 1.8 0.002 17.9 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21116.1 - 2.2e-17 61.7 1.4 0.014 15.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 OEU21116.1 - 2.4e-14 52.7 4.2 0.014 15.3 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OEU21116.1 - 6.6e-08 32.1 2.5 0.032 14.3 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21116.1 - 7.5e-07 29.7 0.0 0.091 13.4 0.1 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21116.1 - 1.2e-06 28.3 3.5 1.5 9.2 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21116.1 - 2.5e-05 24.6 0.3 3.9 8.3 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU21116.1 - 0.00035 20.1 0.9 0.63 9.3 0.0 2.5 2 0 0 2 2 2 2 MalT-like TPR region TPR_17 PF13431.6 OEU21116.1 - 0.00086 19.5 0.5 18 6.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21116.1 - 0.0012 19.5 0.1 15 6.7 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 OEU21116.1 - 0.0055 16.8 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 OEU21116.1 - 0.006 17.1 0.1 0.56 10.8 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU21116.1 - 0.026 14.6 2.6 1.3 9.2 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 OEU21116.1 - 0.11 12.6 0.0 9.3 6.4 0.0 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OEU21116.1 - 0.12 12.1 0.1 50 3.7 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Peptidase_M13 PF01431.21 OEU21118.1 - 1.8e-68 230.2 0.0 3e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 OEU21118.1 - 3e-19 70.0 0.1 3e-19 70.0 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M13 DNA_pol_D_N PF18018.1 OEU21119.1 - 7.8e-22 77.8 0.1 1.2e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 OEU21119.1 - 1.7e-18 66.7 0.1 5.6e-18 65.1 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B His_Phos_1 PF00300.22 OEU21120.1 - 4.2e-06 26.6 0.1 0.0014 18.4 0.0 3.1 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) LRR_6 PF13516.6 OEU21121.1 - 1.9e-18 64.9 57.7 0.039 14.0 0.0 17.3 18 0 0 18 18 18 8 Leucine Rich repeat LRR_8 PF13855.6 OEU21121.1 - 1e-12 47.6 44.6 2e-06 27.5 1.7 8.3 5 3 4 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 OEU21121.1 - 1.4e-12 47.6 61.2 0.026 14.9 0.3 11.7 4 2 12 17 17 17 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU21121.1 - 0.00075 19.7 50.2 4.3 8.3 0.2 15.2 16 1 0 16 16 16 2 Leucine Rich Repeat LRR_9 PF14580.6 OEU21121.1 - 0.021 14.3 8.9 0.047 13.2 0.3 3.7 1 1 1 3 3 3 0 Leucine-rich repeat LSM PF01423.22 OEU21122.1 - 1.7e-12 46.8 1.0 2e-12 46.6 1.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OEU21122.1 - 0.0043 17.1 0.0 0.0052 16.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain 5_nucleotid_C PF02872.18 OEU21123.1 - 2e-07 31.4 0.0 2.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain AsiA PF09010.10 OEU21123.1 - 0.12 12.5 0.0 11 6.3 0.0 2.2 1 1 1 2 2 2 0 Anti-Sigma Factor A V_ATPase_I PF01496.19 OEU21126.1 - 1.9e-266 886.1 8.3 6.2e-265 881.1 8.3 2.3 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family PI3_PI4_kinase PF00454.27 OEU21127.1 - 8.8e-71 238.6 0.1 1.5e-70 237.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OEU21127.1 - 4.7e-52 177.3 0.4 1.1e-51 176.1 0.0 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 OEU21127.1 - 7.8e-50 168.9 0.0 3.6e-46 157.0 0.0 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OEU21127.1 - 9.6e-36 122.2 1.1 2e-35 121.2 0.1 2.2 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OEU21127.1 - 8.6e-13 47.9 0.5 2.7e-12 46.3 0.5 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OEU21127.1 - 4.4e-08 33.4 20.7 0.0039 17.5 0.4 8.9 6 3 1 9 9 9 2 HEAT repeats HEAT PF02985.22 OEU21127.1 - 0.00012 22.0 34.9 0.75 10.2 0.3 10.2 11 0 0 11 11 10 4 HEAT repeat TPR_19 PF14559.6 OEU21127.1 - 0.036 14.6 0.0 0.48 11.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CLASP_N PF12348.8 OEU21127.1 - 0.094 12.3 0.1 2.2 7.8 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal DUF3150 PF11348.8 OEU21127.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) HEAT_EZ PF13513.6 OEU21127.1 - 2.1 8.9 23.6 0.22 12.1 0.7 8.1 9 1 1 10 10 9 0 HEAT-like repeat PCI PF01399.27 OEU21128.1 - 1.1e-22 80.5 0.5 3.4e-22 78.9 0.5 1.9 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OEU21128.1 - 0.0011 19.0 0.1 0.0024 17.9 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OEU21128.1 - 0.019 14.4 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 SAC3/GANP family Type2_restr_D3 PF16902.5 OEU21128.1 - 0.074 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Aminotran_4 PF01063.19 OEU21130.1 - 3.8e-20 72.7 0.0 5.1e-18 65.7 0.0 2.9 1 1 0 1 1 1 1 Amino-transferase class IV ADH_zinc_N_2 PF13602.6 OEU21131.1 - 0.0064 17.5 0.0 0.015 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU21131.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FKBP_C PF00254.28 OEU21132.1 - 1e-19 70.6 0.0 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4827 PF16109.5 OEU21132.1 - 0.0094 16.0 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4827) DnaJ PF00226.31 OEU21133.1 - 1.5e-09 37.8 0.6 4.5e-09 36.3 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain NOD2_WH PF17779.1 OEU21133.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 NOD2 winged helix domain AAA_21 PF13304.6 OEU21133.1 - 1.6 8.5 5.9 1.5 8.5 3.1 1.9 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system EcKinase PF02958.20 OEU21134.1 - 1.2e-10 41.2 2.7 6.5e-07 28.9 0.4 3.5 2 1 1 3 3 3 3 Ecdysteroid kinase APH PF01636.23 OEU21134.1 - 0.00031 20.7 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ntox30 PF15532.6 OEU21134.1 - 0.091 13.1 1.3 4.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin 30 MCM_bind PF09739.9 OEU21135.1 - 2.7e-37 128.5 9.5 4.1e-23 81.7 10.4 2.3 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor adh_short PF00106.25 OEU21136.1 - 1.2e-25 90.1 0.0 1.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU21136.1 - 4.6e-17 62.4 0.0 6.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU21136.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU21136.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OEU21136.1 - 0.033 13.5 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OEU21136.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OEU21136.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain HMA PF00403.26 OEU21138.1 - 6.1e-07 29.8 0.2 2.5e-06 27.9 0.2 1.9 1 1 0 1 1 1 1 Heavy-metal-associated domain MerT PF02411.15 OEU21138.1 - 0.00089 19.3 0.7 0.0016 18.4 0.7 1.5 1 0 0 1 1 1 1 MerT mercuric transport protein VCH_CASS14 PF18315.1 OEU21138.1 - 0.058 13.4 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 Integron cassette protein VCH_CASS1 chain FAD_binding_7 PF03441.14 OEU21140.1 - 1.1e-53 181.8 0.2 1.8e-53 181.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OEU21140.1 - 2.7e-20 73.0 0.0 1.1e-19 71.1 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase DUF3507 PF12015.8 OEU21140.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) RAM PF15320.6 OEU21140.1 - 1.7 9.3 16.8 0.04 14.5 9.4 2.1 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein CPSF_A PF03178.15 OEU21142.1 - 3.1e-50 171.3 0.0 5.3e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OEU21142.1 - 0.0068 15.1 0.0 0.017 13.8 0.0 1.7 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Tyrosinase PF00264.20 OEU21143.1 - 1.6e-31 110.3 14.9 1.1e-16 61.8 0.5 3.0 2 1 1 3 3 3 2 Common central domain of tyrosinase TCR PF03638.15 OEU21145.1 - 7.5e-13 48.6 35.0 4.7e-08 33.2 13.8 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Ocnus PF05005.15 OEU21147.1 - 1.7e-23 82.8 0.1 2.2e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) A_deamin PF02137.18 OEU21148.1 - 1.2e-20 74.3 5.0 5.6e-19 68.8 4.9 2.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_S9 PF00380.19 OEU21149.1 - 4.4e-32 111.1 0.4 5e-32 111.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TPR_1 PF00515.28 OEU21151.1 - 1.1e-17 63.0 0.4 3.2e-08 33.1 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21151.1 - 1.5e-16 59.1 0.2 4.5e-08 32.6 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU21151.1 - 1.5e-11 43.8 1.0 0.00044 19.9 0.2 3.1 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 OEU21151.1 - 1.8e-10 40.2 0.5 7.4e-06 25.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU21151.1 - 2.1e-09 37.1 1.1 0.00051 20.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21151.1 - 9.7e-09 35.7 0.1 1.2e-07 32.2 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21151.1 - 1.3e-08 35.3 0.8 0.00076 19.9 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21151.1 - 3.7e-08 33.5 0.0 6.3e-05 23.5 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OEU21151.1 - 1.1e-07 31.9 0.0 6.3e-06 26.2 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21151.1 - 0.00013 22.4 0.2 0.0017 18.8 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU21151.1 - 0.00031 21.0 0.5 0.024 14.9 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU21151.1 - 0.0061 16.6 0.1 24 5.1 0.1 3.1 1 1 2 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 OEU21151.1 - 0.0069 15.6 0.2 0.048 12.9 0.2 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 OEU21151.1 - 0.032 14.6 0.3 0.32 11.3 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 OEU21151.1 - 0.033 13.2 0.0 0.033 13.2 0.0 1.0 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 OEU21151.1 - 0.038 14.2 0.6 0.061 13.6 0.3 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Metallophos PF00149.28 OEU21152.1 - 1.6e-30 107.2 0.1 2.3e-30 106.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OEU21152.1 - 5.6e-09 36.2 0.0 9.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF478 PF04334.12 OEU21152.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF478) EcoRI PF02963.16 OEU21152.1 - 0.19 10.7 0.0 0.43 9.6 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease EcoRI Thioredoxin PF00085.20 OEU21153.1 - 2.6e-24 85.2 0.2 2.9e-24 85.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU21153.1 - 0.0004 20.8 0.1 0.0022 18.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OEU21153.1 - 0.0021 18.1 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 OEU21153.1 - 0.0047 17.2 0.0 0.048 14.0 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OEU21153.1 - 0.082 12.7 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin TPR_1 PF00515.28 OEU21155.1 - 3.6e-44 146.8 0.4 1e-09 37.8 0.4 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21155.1 - 9e-39 128.5 10.2 4.8e-07 29.4 0.4 7.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21155.1 - 1e-28 97.1 0.0 9.8e-05 22.3 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 OEU21155.1 - 1.6e-24 85.3 0.1 3.2e-06 26.7 0.1 6.9 3 1 4 7 7 7 5 TPR repeat TPR_16 PF13432.6 OEU21155.1 - 4.5e-24 84.8 5.3 4e-08 33.8 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21155.1 - 1.1e-22 80.3 1.9 1.6e-11 44.5 0.1 5.5 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21155.1 - 4e-22 77.0 4.7 0.00012 22.6 0.2 7.2 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OEU21155.1 - 8e-22 77.3 2.9 5.9e-07 29.7 0.1 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 OEU21155.1 - 9.5e-18 63.2 3.3 0.002 18.4 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OEU21155.1 - 4.7e-15 55.5 10.0 5.7e-05 23.2 0.3 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU21155.1 - 2.1e-14 53.5 0.9 4.7e-05 23.5 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OEU21155.1 - 1.4e-13 49.8 0.5 0.064 13.3 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21155.1 - 2.7e-13 49.6 4.9 0.048 14.3 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OEU21155.1 - 6.8e-09 35.3 0.2 1.5e-05 24.3 0.1 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 OEU21155.1 - 2.7e-08 33.7 0.0 0.85 10.4 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 OEU21155.1 - 3.9e-06 27.1 0.1 0.053 13.9 0.1 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU21155.1 - 4.9e-05 23.1 12.0 0.65 9.9 0.2 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU21155.1 - 5.7e-05 23.1 1.9 0.65 10.1 0.1 4.6 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 OEU21155.1 - 7.1e-05 22.4 0.1 0.004 16.8 0.0 2.9 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 OEU21155.1 - 0.00055 19.4 0.0 0.0013 18.2 0.0 1.6 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_21 PF09976.9 OEU21155.1 - 0.0007 19.4 2.4 0.0079 15.9 0.1 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat-like domain TOM20_plant PF06552.12 OEU21155.1 - 0.0085 15.9 0.4 3.3 7.4 0.0 3.8 2 1 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 MAS20 PF02064.15 OEU21155.1 - 0.027 14.6 0.1 7.8 6.6 0.0 3.4 1 1 3 4 4 4 0 MAS20 protein import receptor NARP1 PF12569.8 OEU21155.1 - 0.045 12.7 0.1 0.15 10.9 0.0 1.7 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 OEU21155.1 - 0.049 14.1 3.5 0.15 12.5 0.5 2.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 OEU21155.1 - 0.15 12.1 2.2 2.9 8.0 1.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 OEU21155.1 - 0.18 10.8 0.0 3.7 6.5 0.0 2.2 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Cation_ATPase_C PF00689.21 OEU21156.1 - 0.024 14.4 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus ETRAMP PF09716.10 OEU21156.1 - 0.038 14.0 0.6 0.065 13.3 0.6 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3981 PF13139.6 OEU21156.1 - 0.063 13.7 0.5 0.17 12.2 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3981) BCD PF15461.6 OEU21156.1 - 0.07 12.6 0.4 0.43 10.0 0.6 1.9 1 1 1 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF4179 PF13786.6 OEU21156.1 - 8.5 6.9 9.2 5.3 7.6 4.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) Ribosomal_L23 PF00276.20 OEU21157.1 - 1.5e-15 57.3 0.3 2.1e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 RINGv PF12906.7 OEU21158.1 - 5e-14 52.1 5.6 9.7e-14 51.2 5.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 OEU21158.1 - 0.017 15.2 1.0 0.038 14.0 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OEU21158.1 - 0.065 13.6 4.6 0.12 12.7 4.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 OEU21158.1 - 1.6 8.6 4.1 3.1 7.7 4.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_S49 PF01343.18 OEU21159.1 - 2.4e-39 134.8 0.0 3.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 OEU21159.1 - 4.6e-07 29.9 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 2 Clp protease SDH_sah PF01972.16 OEU21159.1 - 0.00077 18.5 0.0 0.0014 17.7 0.0 1.4 2 0 0 2 2 2 1 Serine dehydrogenase proteinase MgtE PF01769.16 OEU21161.1 - 5.8e-19 68.7 10.0 5.8e-19 68.7 10.0 1.6 2 0 0 2 2 2 1 Divalent cation transporter S1FA PF04689.13 OEU21161.1 - 0.16 12.2 0.5 0.3 11.3 0.5 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA BC10 PF06726.12 OEU21161.1 - 0.19 12.0 3.0 1.8 8.9 2.0 2.5 1 1 1 2 2 2 0 Bladder cancer-related protein BC10 GidB PF02527.15 OEU21162.1 - 2.8e-30 105.0 0.0 4e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 OEU21162.1 - 4.1e-06 26.7 0.0 7.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OEU21162.1 - 0.00088 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase EGF PF00008.27 OEU21163.1 - 1.9e-05 24.8 19.1 0.016 15.5 4.4 2.9 2 1 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 OEU21163.1 - 0.0048 17.2 8.0 0.0048 17.2 8.0 2.8 2 1 0 2 2 2 1 EGF-like domain LAP1C PF05609.12 OEU21166.1 - 0.0022 17.2 21.8 0.0028 16.8 21.8 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) PT PF04886.12 OEU21166.1 - 1.1 8.9 10.9 3.7 7.2 10.9 1.8 1 1 0 1 1 1 0 PT repeat ANAPC4_WD40 PF12894.7 OEU21167.1 - 1.3e-36 124.7 3.8 2.4e-05 24.5 0.0 10.4 4 2 5 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OEU21167.1 - 1.5e-23 82.6 18.5 0.043 14.7 0.0 12.3 12 0 0 12 12 12 7 WD domain, G-beta repeat eIF2A PF08662.11 OEU21167.1 - 1e-08 35.3 0.0 0.038 13.9 0.0 5.1 4 2 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OEU21167.1 - 2.1e-08 33.9 0.1 0.00054 19.4 0.0 4.7 4 2 0 5 5 5 2 WD40-like domain TFIIIC_delta PF12657.7 OEU21167.1 - 0.00029 20.8 7.2 0.069 13.1 0.3 5.3 3 2 0 3 3 3 2 Transcription factor IIIC subunit delta N-term LRR_8 PF13855.6 OEU21168.1 - 6.7e-36 121.9 41.6 1.1e-11 44.3 2.0 6.1 5 1 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 OEU21168.1 - 1.1e-24 83.1 35.3 0.073 13.7 0.5 12.9 13 0 0 13 13 13 8 Leucine Rich Repeat LRR_4 PF12799.7 OEU21168.1 - 4.1e-24 84.2 51.0 0.0002 21.7 5.3 7.8 2 1 9 11 11 11 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU21168.1 - 9e-12 44.1 56.2 0.0035 17.3 0.1 12.8 13 0 0 13 13 13 7 Leucine Rich repeat LRR_2 PF07723.13 OEU21168.1 - 0.11 13.2 0.1 66 4.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 OEU21168.1 - 6.6 6.2 6.7 7.1 6.1 1.7 2.6 2 1 0 2 2 2 0 Leucine-rich repeat DUF1350 PF07082.11 OEU21170.1 - 1.3e-41 142.5 0.1 1.3e-40 139.3 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.7 OEU21170.1 - 0.00014 22.6 0.8 0.0002 22.0 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family WW PF00397.26 OEU21171.1 - 5.8e-22 77.5 15.7 3.9e-11 42.8 5.4 2.1 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OEU21171.1 - 6.8e-05 23.1 5.1 0.022 15.1 0.6 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 OEU21171.1 - 0.032 14.2 0.1 0.82 9.7 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat DUF2147 PF09917.9 OEU21171.1 - 0.11 13.2 3.2 1.9 9.2 0.3 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) YL1_C PF08265.11 OEU21171.1 - 0.11 12.3 3.7 0.71 9.7 0.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Gly_transf_sug PF04488.15 OEU21172.1 - 2.3e-10 41.0 0.0 5.6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OEU21172.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein HSF_DNA-bind PF00447.17 OEU21173.1 - 0.41 11.3 5.7 20 5.9 0.1 2.9 2 1 0 2 2 2 0 HSF-type DNA-binding Sulfotransfer_3 PF13469.6 OEU21174.1 - 7.3e-30 105.0 1.2 2.1e-29 103.4 1.2 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OEU21174.1 - 4.3e-10 39.5 0.0 8.3e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 OEU21174.1 - 0.013 15.0 0.5 0.87 9.1 0.3 2.9 2 1 0 2 2 2 0 Stf0 sulphotransferase PilM_2 PF11104.8 OEU21174.1 - 0.036 13.1 0.3 0.071 12.1 0.3 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Connexin PF00029.19 OEU21174.1 - 0.068 12.9 0.5 0.28 10.9 0.6 1.7 2 0 0 2 2 2 0 Connexin Orf78 PF06024.12 OEU21174.1 - 0.66 10.3 6.1 2.4 8.5 3.8 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Nucleocapsid-N PF11030.8 OEU21174.1 - 2.3 8.1 12.4 0.17 11.8 7.3 1.6 2 0 0 2 2 2 0 Nucleocapsid protein N Motile_Sperm PF00635.26 OEU21175.1 - 1.2e-13 50.9 0.5 4e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 MSP (Major sperm protein) domain zf-RING_UBOX PF13445.6 OEU21175.1 - 0.00021 21.2 3.0 0.00021 21.2 3.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU21175.1 - 0.1 12.9 11.5 0.16 12.3 5.2 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OEU21175.1 - 0.51 10.3 14.8 8.5 6.4 14.8 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OEU21175.1 - 1.1 9.2 10.8 0.092 12.6 4.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU21175.1 - 3.7 7.5 12.8 0.051 13.4 3.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 OEU21177.1 - 0.0012 18.3 4.3 0.18 11.3 2.1 3.0 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase 53-BP1_Tudor PF09038.10 OEU21177.1 - 0.012 15.6 0.1 0.076 13.0 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor SH3_3 PF08239.11 OEU21177.1 - 0.029 14.7 0.8 0.86 9.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain KorB_C PF06613.11 OEU21177.1 - 0.12 12.4 0.1 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain DUF3439 PF11921.8 OEU21177.1 - 0.66 10.0 6.4 0.16 11.9 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pro_isomerase PF00160.21 OEU21178.1 - 1.5e-42 145.6 0.0 1.6e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_31 PF13847.6 OEU21179.1 - 6.2e-13 48.8 0.1 9.4e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21179.1 - 1e-12 48.2 0.0 2.4e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21179.1 - 1.3e-12 48.3 0.0 2.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU21179.1 - 2.4e-11 44.1 0.0 4.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU21179.1 - 9.1e-11 42.4 0.0 1.6e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 OEU21179.1 - 6e-05 22.3 0.1 7.9e-05 21.9 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_32 PF13679.6 OEU21179.1 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU21179.1 - 0.00015 21.4 0.0 0.0028 17.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OEU21179.1 - 0.00034 20.0 0.0 0.0012 18.3 0.1 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 OEU21179.1 - 0.0029 17.2 0.1 0.0057 16.3 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.17 OEU21179.1 - 0.0039 16.4 0.2 0.56 9.3 0.0 3.1 2 1 2 4 4 4 1 NNMT/PNMT/TEMT family TehB PF03848.14 OEU21179.1 - 0.0058 16.1 0.2 0.0088 15.5 0.2 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 OEU21179.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.13 OEU21179.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OEU21179.1 - 0.08 11.8 0.1 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OEU21179.1 - 0.2 11.5 0.0 14 5.5 0.0 2.1 1 1 0 2 2 2 0 Hypothetical methyltransferase Aa_trans PF01490.18 OEU21180.1 - 5.2e-57 193.4 25.2 6.7e-57 193.0 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU21180.1 - 1.9e-05 23.9 15.4 1.9e-05 23.9 15.4 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF1071 PF06378.11 OEU21180.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) HSF_DNA-bind PF00447.17 OEU21181.1 - 3.7e-19 69.1 0.2 4.4e-19 68.9 0.2 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Acyltransferase PF01553.21 OEU21182.1 - 8.9e-07 28.6 0.0 2.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Proteasome PF00227.26 OEU21183.1 - 1e-42 145.8 0.0 1.3e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OEU21183.1 - 2.9e-10 39.6 0.0 4.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DAHP_synth_2 PF01474.16 OEU21184.1 - 1.2e-185 617.3 0.0 1.3e-185 617.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Tsi6 PF18660.1 OEU21184.1 - 0.2 11.7 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 Tsi6 DUF4636 PF15468.6 OEU21185.1 - 0.19 11.4 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF3752 PF12572.8 OEU21186.1 - 0.00018 22.0 2.9 0.00018 22.0 2.9 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3752) Amidohydro_2 PF04909.14 OEU21187.1 - 4.5e-18 66.0 0.1 9.1e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase Presenilin PF01080.17 OEU21188.1 - 1.8 7.3 5.0 0.61 8.8 0.8 1.9 2 0 0 2 2 2 0 Presenilin RRF PF01765.19 OEU21189.1 - 0.018 15.0 1.4 0.018 15.0 1.4 2.4 1 1 1 2 2 2 0 Ribosome recycling factor DUF883 PF05957.13 OEU21189.1 - 0.033 14.8 0.1 0.033 14.8 0.1 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TetR_C_25 PF17933.1 OEU21189.1 - 0.039 14.3 0.3 0.064 13.6 0.3 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PcfK PF14058.6 OEU21189.1 - 0.24 11.7 8.3 0.031 14.6 4.3 1.6 2 0 0 2 2 2 0 PcfK-like protein YtxH PF12732.7 OEU21189.1 - 0.56 10.8 0.1 0.56 10.8 0.1 2.3 2 0 0 2 2 2 0 YtxH-like protein T3SS_basalb_I PF17001.5 OEU21189.1 - 1.7 9.3 6.3 0.3 11.7 1.7 2.1 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI ATP-synt_B PF00430.18 OEU21189.1 - 1.8 8.6 6.8 0.27 11.3 1.0 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Cyt-b5 PF00173.28 OEU21190.1 - 9.6e-10 38.5 0.1 1.7e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NOA36 PF06524.12 OEU21190.1 - 4.4 6.5 12.9 6 6.1 12.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 OEU21190.1 - 8.2 5.5 14.5 11 5.0 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ArfGap PF01412.18 OEU21192.1 - 1.9e-34 118.2 0.2 2.2e-34 118.0 0.2 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-Di19 PF05605.12 OEU21193.1 - 0.0039 17.4 0.9 0.3 11.4 0.2 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding MRNIP PF15749.5 OEU21193.1 - 0.025 15.3 15.0 0.025 15.3 15.0 2.2 1 1 1 2 2 2 0 MRN-interacting protein DUF678 PF05077.12 OEU21193.1 - 0.027 14.6 0.7 0.027 14.6 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF678) PhyH PF05721.13 OEU21193.1 - 0.73 10.1 3.8 0.61 10.3 1.6 1.7 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) C1_2 PF03107.16 OEU21193.1 - 9.1 6.7 10.4 29 5.1 0.0 3.6 4 0 0 4 4 4 0 C1 domain Proteasome PF00227.26 OEU21194.1 - 2.8e-25 88.9 1.8 2.3e-24 85.9 1.8 2.2 1 1 0 1 1 1 1 Proteasome subunit DUF3446 PF11928.8 OEU21194.1 - 0.078 13.3 13.1 1.4 9.3 8.0 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 OEU21194.1 - 0.15 11.6 15.5 0.14 11.8 8.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OEU21194.1 - 0.48 11.1 12.5 1.3 9.7 5.1 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Lipase_GDSL_2 PF13472.6 OEU21195.1 - 0.028 14.8 0.0 0.032 14.6 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 OEU21195.1 - 0.054 13.6 0.3 0.22 11.6 0.3 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Adaptin_N PF01602.20 OEU21196.1 - 3.7e-82 276.6 4.1 4.3e-82 276.3 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OEU21196.1 - 3.7e-41 140.9 2.5 3.8e-39 134.3 0.2 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OEU21196.1 - 9.6e-08 32.3 1.5 0.12 12.8 0.0 5.0 3 2 4 7 7 7 4 HEAT repeats SPO22 PF08631.10 OEU21196.1 - 0.00044 19.8 0.2 0.011 15.2 0.0 2.6 2 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like HEAT PF02985.22 OEU21196.1 - 0.00053 20.0 0.2 21 5.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat RTP1_C1 PF10363.9 OEU21196.1 - 0.0078 16.4 0.1 0.33 11.1 0.0 3.3 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 AAA_lid_4 PF17864.1 OEU21196.1 - 0.084 12.6 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 RuvB AAA lid domain B2-adapt-app_C PF09066.10 OEU21197.1 - 7.4e-11 42.1 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HA PF03457.14 OEU21198.1 - 2.3e-37 127.1 7.0 4.8e-18 65.2 0.1 3.9 3 1 0 3 3 3 3 Helicase associated domain MFS_1 PF07690.16 OEU21200.1 - 4.1e-32 111.5 25.8 4.1e-32 111.5 25.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OEU21200.1 - 7.6e-06 24.7 11.3 2.4e-05 23.1 0.1 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 OEU21200.1 - 4e-05 22.7 17.7 0.00078 18.4 2.6 3.4 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 OEU21200.1 - 0.00013 21.0 7.0 0.081 11.8 0.3 3.6 3 2 1 4 4 4 4 MFS_1 like family BT1 PF03092.16 OEU21200.1 - 0.02 13.1 3.4 0.058 11.6 0.1 2.2 2 0 0 2 2 2 0 BT1 family DUF5337 PF17272.2 OEU21200.1 - 0.12 12.3 0.7 0.54 10.1 0.7 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5337) DUF2615 PF11027.8 OEU21200.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) MFS_3 PF05977.13 OEU21200.1 - 0.26 9.6 27.3 0.13 10.6 20.8 2.7 2 1 0 2 2 2 0 Transmembrane secretion effector CMS1 PF14617.6 OEU21201.1 - 1.3e-13 50.9 11.3 4.6e-13 49.1 11.3 1.7 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OEU21201.1 - 4.9e-05 23.2 0.4 9.9e-05 22.2 0.4 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3658 PF12395.8 OEU21201.1 - 0.1 12.5 0.3 5.4 7.0 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function PsbP PF01789.16 OEU21202.1 - 4.4e-17 62.6 0.0 2.6e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 PsbP SR-25 PF10500.9 OEU21202.1 - 0.046 13.3 8.2 0.076 12.6 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ten_N PF06484.12 OEU21202.1 - 0.051 13.5 3.3 0.08 12.8 3.3 1.2 1 0 0 1 1 1 0 Teneurin Intracellular Region DGF-1_C PF11040.8 OEU21202.1 - 1.2 9.2 4.4 1.9 8.6 1.1 2.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CheR PF01739.18 OEU21205.1 - 2.6e-07 30.3 0.0 2e-06 27.4 0.0 2.0 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.6 OEU21205.1 - 0.0002 21.2 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21205.1 - 0.048 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21205.1 - 0.05 14.3 0.0 0.12 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TPT PF03151.16 OEU21206.1 - 4.7e-18 65.5 16.7 8e-18 64.8 16.7 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family PS_pyruv_trans PF04230.13 OEU21206.1 - 3.6e-07 30.4 0.0 6.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Gly_transf_sug PF04488.15 OEU21206.1 - 0.0091 16.6 0.2 0.036 14.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif EamA PF00892.20 OEU21206.1 - 0.06 13.5 22.9 0.99 9.6 7.5 3.2 2 1 0 2 2 2 0 EamA-like transporter family Dehydrin PF00257.19 OEU21207.1 - 1.4 9.5 5.4 18 5.9 5.4 2.3 1 1 0 1 1 1 0 Dehydrin Arm PF00514.23 OEU21208.1 - 8.7e-42 139.9 16.9 2.8e-10 39.9 0.0 7.2 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OEU21208.1 - 1.5e-10 41.4 1.5 0.013 16.0 0.0 6.4 5 2 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 OEU21208.1 - 2e-09 37.7 0.0 6.2e-06 26.5 0.0 3.8 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 OEU21208.1 - 4.3e-09 35.8 1.5 1 9.8 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Arm_3 PF16186.5 OEU21208.1 - 1.2e-05 24.8 0.0 0.0041 16.6 0.0 2.4 2 0 0 2 2 2 2 Atypical Arm repeat NopRA1 PF16201.5 OEU21208.1 - 5.3e-05 22.9 0.0 0.068 12.7 0.0 2.7 3 0 0 3 3 3 2 Nucleolar pre-ribosomal-associated protein 1 V-ATPase_H_C PF11698.8 OEU21208.1 - 0.1 12.7 0.0 1.5 9.0 0.0 2.8 3 1 1 4 4 4 0 V-ATPase subunit H RSRP PF17069.5 OEU21208.1 - 0.18 11.3 2.6 0.32 10.5 2.6 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 AcetylCoA_hyd_C PF13336.6 OEU21209.1 - 1.2e-45 155.2 0.0 1.9e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 OEU21209.1 - 5.7e-13 49.3 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Acetyltransf_1 PF00583.25 OEU21209.1 - 0.0015 18.8 0.0 0.0044 17.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OEU21209.1 - 0.0087 16.7 0.0 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBF PF03914.17 OEU21210.1 - 5.4e-33 114.4 0.0 5.4e-33 114.4 0.0 3.4 4 0 0 4 4 4 1 CBF/Mak21 family PCI PF01399.27 OEU21211.1 - 3.2e-05 24.4 0.0 6.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3648 PF12364.8 OEU21211.1 - 0.0041 17.3 0.2 0.0085 16.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) ICMT PF04140.14 OEU21212.1 - 6.3e-29 100.3 0.5 6.3e-29 100.3 0.5 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OEU21212.1 - 3.2e-13 50.0 0.7 3.2e-13 50.0 0.7 2.6 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 OEU21212.1 - 7e-05 22.5 3.7 9.1e-05 22.1 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 OEU21212.1 - 0.00056 19.5 1.1 0.00088 18.8 0.7 1.5 1 1 0 1 1 1 1 NnrU protein APOC4 PF15119.6 OEU21212.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein C4 HSP90 PF00183.18 OEU21213.1 - 3.9e-229 761.8 25.1 5e-229 761.5 25.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OEU21213.1 - 1.5e-14 54.5 0.1 2.9e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OEU21213.1 - 7.9e-11 41.9 0.4 2e-10 40.6 0.4 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2849 PF11011.8 OEU21213.1 - 0.15 12.7 0.0 0.15 12.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) RNA_pol_Rpc4 PF05132.14 OEU21213.1 - 0.69 10.3 3.7 1.8 9.0 3.7 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1041 PF06292.17 OEU21213.1 - 2.2 8.7 6.7 0.86 10.0 0.2 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1041) DOT1 PF08123.13 OEU21214.1 - 1.3e-09 37.9 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF3506 PF12014.8 OEU21215.1 - 4.7e-12 46.1 0.0 2e-10 40.8 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) SLATT_4 PF18186.1 OEU21215.1 - 0.11 12.2 1.7 0.18 11.5 1.7 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF1090 PF06476.12 OEU21215.1 - 0.89 9.7 4.4 0.46 10.6 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF4201 PF13870.6 OEU21215.1 - 4.7 6.9 11.6 0.38 10.5 3.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) zinc_ribbon_2 PF13240.6 OEU21216.1 - 0.00014 21.4 10.4 0.00059 19.5 1.2 3.5 3 0 0 3 3 3 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 OEU21216.1 - 0.0017 17.7 11.6 0.0051 16.2 4.6 2.7 2 0 0 2 2 2 2 zinc-ribbon domain NOB1_Zn_bind PF08772.11 OEU21216.1 - 0.0018 18.4 4.1 0.0018 18.4 4.1 2.4 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 OEU21216.1 - 0.015 15.3 10.8 0.015 15.3 10.8 2.7 1 1 1 2 2 2 0 Double zinc ribbon PLATZ PF04640.14 OEU21216.1 - 0.023 15.3 2.6 0.023 15.3 2.6 2.3 2 0 0 2 2 2 0 PLATZ transcription factor Menin PF05053.13 OEU21216.1 - 0.2 10.0 1.4 0.22 9.8 1.4 1.1 1 0 0 1 1 1 0 Menin Siva PF05458.12 OEU21216.1 - 0.42 10.3 10.7 0.18 11.5 8.3 1.5 1 1 0 1 1 1 0 Cd27 binding protein (Siva) UPF0547 PF10571.9 OEU21216.1 - 0.54 10.4 9.7 4 7.6 0.5 3.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 OEU21216.1 - 5 7.1 12.6 14 5.7 2.0 3.7 3 0 0 3 3 3 0 Nudix N-terminal Secretin_N_2 PF07655.13 OEU21216.1 - 5.3 7.6 22.3 1.6 9.3 9.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain zinc_ribbon_4 PF13717.6 OEU21216.1 - 8.1 6.5 12.5 3 7.8 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IF3_C PF00707.22 OEU21217.1 - 1.3e-09 37.8 0.2 2.1e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 OEU21217.1 - 5.5e-09 36.2 0.0 1.8e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain DDE_Tnp_1_2 PF13586.6 OEU21217.1 - 0.087 13.2 0.2 0.24 11.8 0.2 1.7 1 0 0 1 1 1 0 Transposase DDE domain AAA PF00004.29 OEU21218.1 - 4.1e-43 147.0 0.0 7.2e-35 120.3 0.0 2.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU21218.1 - 1.5e-14 53.5 0.1 4.2e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OEU21218.1 - 0.0003 21.2 0.1 0.015 15.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OEU21218.1 - 0.0019 18.2 0.1 0.055 13.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU21218.1 - 0.0085 15.8 0.0 0.098 12.4 0.0 2.6 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OEU21218.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 OEU21218.1 - 0.05 13.8 0.0 0.095 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OEU21218.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OEU21218.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Cir_N PF10197.9 OEU21219.1 - 0.00011 22.3 5.4 0.00011 22.3 5.4 2.4 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 OEU21219.1 - 0.073 12.9 0.8 0.17 11.8 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3123 PF11321.8 OEU21219.1 - 3.3 8.4 11.0 4 8.1 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Antimicrobial_2 PF08023.12 OEU21220.1 - 0.00062 20.2 2.2 0.87 10.2 0.1 2.9 2 1 1 3 3 3 2 Frog antimicrobial peptide LRR_6 PF13516.6 OEU21221.1 - 7.6e-12 44.3 11.4 0.0012 18.8 0.1 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OEU21221.1 - 0.0039 17.5 4.3 0.56 11.0 0.0 4.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 OEU21221.1 - 0.011 15.5 7.4 5 7.0 0.3 4.5 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 OEU21221.1 - 0.051 14.0 1.2 0.051 14.0 1.2 3.7 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) IlvC PF01450.19 OEU21221.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain SOBP PF15279.6 OEU21222.1 - 0.097 13.3 8.9 0.15 12.6 8.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein LpxB PF02684.15 OEU21222.1 - 3.3 6.5 8.0 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase Fcf1 PF04900.12 OEU21224.1 - 1.7e-33 115.0 1.2 3.2e-33 114.1 1.2 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OEU21224.1 - 1.2e-12 48.2 0.0 2.4e-12 47.2 0.0 1.5 2 0 0 2 2 2 1 PIN like domain Rab5ip PF07019.12 OEU21225.1 - 3.2e-16 59.7 5.7 3.9e-16 59.4 5.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Complex1_LYR PF05347.15 OEU21226.1 - 2.5e-07 30.6 1.3 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OEU21226.1 - 0.021 15.6 0.2 0.033 15.0 0.2 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Nuc_sug_transp PF04142.15 OEU21227.1 - 9.2e-59 199.1 25.4 1.5e-58 198.5 25.4 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OEU21227.1 - 1.1e-11 45.1 28.2 6e-09 36.2 6.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OEU21227.1 - 7e-06 25.5 19.6 2.7e-05 23.6 19.7 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 OEU21227.1 - 8.7e-06 25.1 22.5 0.0013 18.0 22.4 3.2 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 OEU21227.1 - 0.033 13.5 20.8 0.086 12.2 20.8 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family DMT_6 PF04342.12 OEU21227.1 - 5.8 7.2 12.3 4.5 7.5 3.1 3.5 2 1 2 4 4 4 0 Putative member of DMT superfamily (DUF486) MFS_1 PF07690.16 OEU21229.1 - 1.3e-25 90.1 39.7 1.1e-19 70.6 21.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OEU21229.1 - 5.8e-08 31.7 10.6 0.00016 20.3 0.0 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein TssO PF17561.2 OEU21229.1 - 0.028 14.5 0.7 0.061 13.4 0.1 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO UPF0239 PF06783.11 OEU21229.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF1158 PF06643.11 OEU21229.1 - 0.086 13.4 1.8 4 8.0 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1158) DSPc PF00782.20 OEU21230.1 - 1.8e-07 31.0 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OEU21230.1 - 0.0017 18.5 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OEU21230.1 - 0.0078 15.8 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 OEU21231.1 - 1.9e-69 234.0 0.0 2.3e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21231.1 - 2.8e-42 144.8 0.0 3.4e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU21231.1 - 8.3e-05 22.0 0.0 0.00032 20.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OEU21231.1 - 0.0052 16.7 0.7 2.5 8.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU21231.1 - 0.012 14.4 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OEU21231.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OEU21231.1 - 0.087 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRG PF05712.13 OEU21232.1 - 4.5e-20 71.8 1.3 2e-12 46.9 0.0 4.7 3 1 1 4 4 4 4 MRG Tudor-knot PF11717.8 OEU21232.1 - 0.0074 16.2 5.8 0.029 14.3 5.8 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Longin PF13774.6 OEU21233.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain RXT2_N PF08595.11 OEU21233.1 - 0.14 12.2 2.9 0.3 11.1 2.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OEU21233.1 - 0.15 11.7 1.8 0.33 10.6 1.8 1.5 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 OEU21233.1 - 0.43 10.3 7.9 0.82 9.3 7.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VPS9 PF02204.18 OEU21234.1 - 4.9e-13 49.2 0.0 1.3e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PDZ_6 PF17820.1 OEU21234.1 - 0.033 14.0 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 PDZ domain LRR_8 PF13855.6 OEU21236.1 - 0.22 11.3 6.5 12 5.8 0.2 4.5 4 1 0 4 4 4 0 Leucine rich repeat Nitroreductase PF00881.24 OEU21238.1 - 1.2e-19 71.0 0.0 2.6e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 Nitroreductase family Sulfotransfer_2 PF03567.14 OEU21240.1 - 2.4e-08 34.2 0.1 3.7e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family HA2 PF04408.23 OEU21241.1 - 3.2e-26 91.7 0.1 6.1e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OEU21241.1 - 2.3e-23 82.3 0.0 4.6e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OEU21241.1 - 2e-11 44.2 0.0 4.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU21241.1 - 0.0099 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pyr_redox_2 PF07992.14 OEU21242.1 - 1.8e-53 181.7 1.3 2.4e-53 181.3 1.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU21242.1 - 3.2e-28 98.2 0.4 7.4e-28 97.0 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU21242.1 - 4.4e-18 65.6 0.2 1.1e-17 64.3 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU21242.1 - 0.00041 19.7 0.4 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU21242.1 - 0.00055 19.1 2.6 0.00055 19.1 2.6 2.2 3 1 1 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.14 OEU21242.1 - 0.0049 15.6 4.1 0.26 9.9 0.1 3.0 3 1 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OEU21242.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OEU21242.1 - 0.018 14.3 0.4 0.14 11.4 0.1 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 OEU21242.1 - 0.037 14.5 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 OEU21242.1 - 0.046 12.8 0.1 0.36 9.9 0.0 2.2 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 OEU21242.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OEU21242.1 - 0.08 13.0 0.3 0.3 11.2 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 OEU21242.1 - 0.083 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_binding_2 PF00890.24 OEU21242.1 - 0.13 11.4 2.6 0.38 9.8 1.8 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 OEU21242.1 - 1 9.7 5.4 22 5.4 0.9 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OEU21242.1 - 1.3 8.3 3.4 4.5 6.5 1.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_M41 PF01434.18 OEU21243.1 - 2.5e-58 197.1 0.7 4.1e-58 196.4 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OEU21243.1 - 3.8e-44 150.3 0.0 8.2e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU21243.1 - 5.3e-12 45.3 0.1 1.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 OEU21243.1 - 0.00019 20.7 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OEU21243.1 - 0.0011 19.1 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OEU21243.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 OEU21243.1 - 0.0014 19.0 0.2 0.0041 17.4 0.2 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 OEU21243.1 - 0.0073 16.3 0.1 0.041 13.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU21243.1 - 0.0077 16.6 0.2 0.17 12.3 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OEU21243.1 - 0.013 15.8 0.8 0.26 11.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 OEU21243.1 - 0.021 15.0 0.0 0.047 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OEU21243.1 - 0.049 14.0 0.2 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OEU21243.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 OEU21243.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OEU21243.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SET PF00856.28 OEU21244.1 - 1.4e-10 41.9 2.4 1.4e-10 41.9 2.4 2.5 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.18 OEU21244.1 - 1.7e-05 24.8 9.7 1.7e-05 24.8 9.7 4.4 4 1 0 4 4 4 1 MYND finger FA_hydroxylase PF04116.13 OEU21245.1 - 2.7e-19 69.8 16.3 4.1e-19 69.3 14.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UPF0242 PF06785.11 OEU21245.1 - 0.34 11.0 2.7 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RNase_P_Rpp14 PF01900.19 OEU21246.1 - 7.4e-07 29.4 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family TAP42 PF04177.12 OEU21246.1 - 0.071 12.2 0.1 0.09 11.9 0.1 1.1 1 0 0 1 1 1 0 TAP42-like family SAP PF02037.27 OEU21247.1 - 7.8e-12 44.7 1.5 1.4e-11 43.9 1.5 1.4 1 0 0 1 1 1 1 SAP domain CS PF04969.16 OEU21247.1 - 1e-06 29.7 0.7 1.2e-05 26.2 0.1 2.9 2 1 1 3 3 3 1 CS domain Telomere_Sde2_2 PF13297.6 OEU21247.1 - 0.019 14.6 0.1 0.061 13.0 0.1 1.8 1 0 0 1 1 1 0 Telomere stability C-terminal HeH PF12949.7 OEU21247.1 - 0.052 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 HeH/LEM domain DUF1676 PF07898.13 OEU21247.1 - 1.1 9.3 2.9 2.6 8.0 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) PPR_2 PF13041.6 OEU21248.1 - 1.2e-35 121.5 0.4 1.2e-06 28.6 0.0 12.0 9 3 2 11 11 11 7 PPR repeat family PPR_1 PF12854.7 OEU21248.1 - 1.7e-19 69.2 26.6 0.17 11.6 0.0 14.2 16 2 0 16 16 16 8 PPR repeat PPR_3 PF13812.6 OEU21248.1 - 2.6e-18 65.9 0.5 0.0012 18.8 0.0 9.1 9 3 0 9 9 9 4 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU21248.1 - 7e-06 25.6 0.1 0.4 10.0 0.0 5.0 2 1 4 7 7 7 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OEU21248.1 - 0.0043 17.2 35.0 5.5 7.5 0.0 14.1 17 1 0 17 17 17 1 PPR repeat CTP_synth_N PF06418.14 OEU21248.1 - 0.066 12.5 0.1 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 CTP synthase N-terminus Sel1 PF08238.12 OEU21249.1 - 4.9e-21 74.7 4.9 7.8e-06 26.4 0.0 4.9 5 0 0 5 5 4 4 Sel1 repeat TPR_2 PF07719.17 OEU21249.1 - 2.1e-12 46.1 11.8 4.3e-05 23.3 0.2 5.7 7 0 0 7 7 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21249.1 - 2.2e-10 39.9 8.1 0.0012 18.5 0.2 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21249.1 - 7.1e-09 36.2 1.5 0.28 11.9 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU21249.1 - 7.4e-09 35.8 0.9 0.091 13.1 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21249.1 - 2e-06 27.6 8.4 0.01 16.0 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU21249.1 - 5.8e-06 25.9 0.8 0.00043 19.9 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 OEU21249.1 - 0.00018 22.0 0.0 2.9 8.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OEU21249.1 - 0.00022 21.0 0.2 0.33 10.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21249.1 - 0.0057 17.2 0.3 12 6.8 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21249.1 - 0.1 13.1 2.2 14 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OEU21249.1 - 0.14 12.2 3.1 2.3 8.3 0.0 3.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain zf-P11 PF03854.14 OEU21249.1 - 0.32 10.7 4.9 9.6 6.0 0.6 2.6 2 0 0 2 2 2 0 P-11 zinc finger RabGAP-TBC PF00566.18 OEU21251.1 - 8.2e-30 104.1 1.6 5.5e-28 98.1 1.7 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 OEU21253.1 - 1.6e-06 27.8 0.1 0.00039 20.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 OEU21253.1 - 0.018 15.1 2.3 0.018 15.1 2.3 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 OEU21253.1 - 2.3 7.2 5.2 5.7 5.9 5.2 1.6 1 0 0 1 1 1 0 Drosophila roughex protein NDK PF00334.19 OEU21254.1 - 1.4e-53 180.5 0.0 1.7e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase 5_nucleotid PF05761.14 OEU21256.1 - 7.5e-115 384.4 0.0 8.5e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family 5_3_exonuc_N PF02739.16 OEU21256.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Guanylate_kin PF00625.21 OEU21259.1 - 6.4e-50 169.4 0.1 7.3e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase Rad17 PF03215.15 OEU21259.1 - 0.0023 17.9 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 OEU21259.1 - 0.0029 18.2 0.3 0.013 16.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU21259.1 - 0.0035 17.7 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OEU21259.1 - 0.0058 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 OEU21259.1 - 0.011 15.8 0.1 0.069 13.2 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OEU21259.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OEU21259.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OEU21259.1 - 0.13 12.5 0.3 1.9 8.7 0.2 2.3 2 2 0 2 2 2 0 AAA domain GLTP PF08718.11 OEU21260.1 - 2.9e-16 60.1 0.0 7.3e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF3117 PF11314.8 OEU21260.1 - 0.19 11.6 0.2 0.46 10.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) GLTP PF08718.11 OEU21261.1 - 4.8e-14 52.9 0.1 2e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) DUF1522 PF07482.11 OEU21261.1 - 0.014 15.7 1.0 6.5 7.1 0.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) DUF4602 PF15375.6 OEU21262.1 - 1.3e-11 44.9 17.2 2.8e-11 43.9 17.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Gar1 PF04410.14 OEU21263.1 - 1.7e-30 105.9 0.0 1.9e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ArfGap PF01412.18 OEU21264.1 - 2.8e-22 79.0 0.9 3.1e-22 78.9 0.9 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TPR_12 PF13424.6 OEU21265.1 - 1.6e-14 53.9 15.5 8.9e-06 25.9 0.2 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 OEU21265.1 - 7.9e-13 48.2 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 OEU21265.1 - 1.6e-09 37.3 6.1 0.0039 17.0 0.3 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat PA PF02225.22 OEU21265.1 - 1e-05 25.4 0.1 2.6e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 PA domain TPR_2 PF07719.17 OEU21265.1 - 5.2e-05 23.0 13.7 0.0018 18.3 0.1 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 OEU21265.1 - 0.00056 20.3 0.0 0.0022 18.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.28 OEU21265.1 - 0.0011 18.7 3.3 0.22 11.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU21265.1 - 0.002 18.0 9.6 1.4 9.1 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21265.1 - 0.0028 17.7 1.1 10 6.6 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21265.1 - 0.04 14.7 7.1 0.61 11.0 0.7 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ATPase PF06745.13 OEU21265.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC HemS PF05171.12 OEU21265.1 - 0.18 11.8 0.4 0.67 9.9 0.1 2.1 2 0 0 2 2 2 0 Haemin-degrading HemS.ChuX domain ETRAMP PF09716.10 OEU21265.1 - 4.9 7.3 5.7 38 4.4 2.9 2.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SAM_MT PF04445.13 OEU21266.1 - 1.5e-40 139.1 1.6 4.3e-26 91.8 0.6 2.3 1 1 1 2 2 2 2 Putative SAM-dependent methyltransferase Cons_hypoth95 PF03602.15 OEU21266.1 - 1.5e-05 24.7 0.6 0.0065 16.1 0.3 2.2 1 1 1 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_30 PF05430.11 OEU21266.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase TMP-TENI PF02581.17 OEU21266.1 - 0.055 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase Met_10 PF02475.16 OEU21266.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein bZIP_1 PF00170.21 OEU21267.1 - 1.6e-09 37.7 11.1 1.6e-09 37.7 11.1 3.5 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 OEU21267.1 - 0.015 15.3 13.6 0.015 15.3 13.6 4.1 3 0 0 3 3 3 0 Basic region leucine zipper RskA PF10099.9 OEU21267.1 - 3 8.1 11.1 5.6 7.2 0.3 2.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA HLH PF00010.26 OEU21268.1 - 0.0003 20.7 0.2 0.00074 19.4 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PROL5-SMR PF15621.6 OEU21268.1 - 0.42 11.2 0.1 0.42 11.2 0.1 2.4 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family His_Phos_2 PF00328.22 OEU21271.1 - 1.1e-20 74.3 0.5 8.9e-20 71.4 0.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAD_binding_5 PF07994.12 OEU21272.1 - 8.2e-55 186.4 0.0 1e-54 186.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OEU21272.1 - 5.1e-27 94.3 0.1 7.8e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ABC2_membrane PF01061.24 OEU21273.1 - 5.9e-79 264.3 54.2 2.4e-40 138.2 19.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OEU21273.1 - 9.2e-40 136.3 0.0 5.5e-21 75.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 OEU21273.1 - 1.6e-06 28.6 0.1 0.05 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OEU21273.1 - 7e-06 26.1 0.0 0.18 11.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU21273.1 - 8.3e-06 25.8 0.4 0.0004 20.3 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OEU21273.1 - 1.2e-05 25.0 0.9 0.009 15.7 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OEU21273.1 - 4.1e-05 22.8 47.6 0.00012 21.4 18.6 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 OEU21273.1 - 0.00016 21.4 0.3 0.0053 16.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OEU21273.1 - 0.00041 20.6 0.3 0.6 10.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 OEU21273.1 - 0.00075 19.0 0.2 3 7.2 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OEU21273.1 - 0.0035 17.4 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OEU21273.1 - 0.005 17.4 0.1 0.15 12.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OEU21273.1 - 0.021 14.1 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 OEU21273.1 - 0.032 14.0 0.4 3.7 7.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OEU21273.1 - 0.049 14.2 0.2 7.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU21273.1 - 0.058 12.9 0.1 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OEU21273.1 - 0.066 12.9 0.9 1.5 8.5 0.2 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OEU21273.1 - 0.071 13.3 0.4 9.7 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OEU21273.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Roc PF08477.13 OEU21273.1 - 0.094 12.9 0.0 28 4.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3379 PF11859.8 OEU21273.1 - 0.2 10.9 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Mg_chelatase PF01078.21 OEU21273.1 - 0.4 10.0 2.1 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TF_Zn_Ribbon PF08271.12 OEU21274.1 - 0.00047 19.6 0.4 0.0012 18.4 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding OTU PF02338.19 OEU21276.1 - 1.3e-08 35.4 0.0 3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease BRCT PF00533.26 OEU21276.1 - 4.3e-05 23.8 0.0 0.00012 22.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TPR_1 PF00515.28 OEU21277.1 - 4.1e-20 70.7 30.3 0.0008 19.1 0.1 12.9 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21277.1 - 1.2e-18 65.7 48.4 0.0058 16.7 0.3 13.8 16 0 0 16 16 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21277.1 - 1.6e-18 67.0 27.4 0.0051 17.3 1.1 10.1 6 4 5 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 OEU21277.1 - 9.6e-17 61.0 34.3 5.1e-06 26.7 2.2 8.9 8 2 4 12 12 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21277.1 - 3.8e-15 56.3 20.0 0.0024 18.5 1.4 7.5 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21277.1 - 5.2e-14 51.7 24.4 0.17 12.8 0.0 10.0 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21277.1 - 2.7e-13 49.0 22.2 0.15 12.3 0.0 12.2 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 OEU21277.1 - 2.3e-07 30.7 22.2 0.064 13.7 0.1 10.1 11 0 0 11 11 9 1 Tetratricopeptide repeat PknG_TPR PF16918.5 OEU21277.1 - 2.1e-06 26.7 4.5 0.079 11.7 0.1 4.5 3 2 1 4 4 4 2 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 OEU21277.1 - 3.6e-06 27.1 20.4 8.4e-05 22.7 0.2 5.4 6 0 0 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OEU21277.1 - 8.2e-06 25.5 21.9 3 8.1 0.1 9.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU21277.1 - 2.3e-05 24.0 34.4 0.49 10.1 0.1 10.3 12 1 1 13 13 12 3 TPR repeat TPR_4 PF07721.14 OEU21277.1 - 0.0002 21.7 9.4 58 4.7 0.0 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21277.1 - 0.0012 19.4 35.7 0.15 12.7 0.5 10.3 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_9 PF13371.6 OEU21277.1 - 0.0083 16.2 12.7 0.1 12.8 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat CNOT11 PF10155.9 OEU21277.1 - 0.024 14.8 0.3 0.075 13.2 0.3 1.8 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 TPR_10 PF13374.6 OEU21277.1 - 0.19 11.6 0.1 0.19 11.6 0.1 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF948 PF06103.11 OEU21277.1 - 7 7.0 6.9 0.66 10.3 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_transf_49 PF13896.6 OEU21278.1 - 1e-16 61.2 0.0 2.6e-14 53.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan NAD_binding_2 PF03446.15 OEU21279.1 - 5.4e-27 94.9 0.3 8.9e-27 94.2 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OEU21279.1 - 2.7e-22 79.3 0.2 4.7e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OEU21279.1 - 0.00012 22.6 0.1 0.00029 21.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OEU21279.1 - 0.00074 19.6 0.3 0.0026 17.8 0.0 2.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OEU21279.1 - 0.027 14.3 0.2 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEXIM PF15313.6 OEU21279.1 - 0.047 13.9 0.2 0.072 13.3 0.2 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein Cupin_8 PF13621.6 OEU21280.1 - 3.5e-45 154.7 0.3 4.6e-45 154.3 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OEU21280.1 - 0.00083 18.9 0.0 0.85 9.0 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein DUF5610 PF18433.1 OEU21280.1 - 0.024 15.1 1.0 0.09 13.3 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) RRN3 PF05327.11 OEU21280.1 - 5.2 5.5 11.5 6.5 5.2 11.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP-synt_10 PF05176.14 OEU21282.1 - 2.7e-26 92.3 0.1 4.1e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 ATP10 protein TetR_C_30 PF17939.1 OEU21282.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Mtr2 PF10429.9 OEU21282.1 - 0.047 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 YtfJ_HI0045 PF09695.10 OEU21282.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) TPR_12 PF13424.6 OEU21283.1 - 3.7e-36 123.2 0.1 4.5e-12 46.1 0.0 4.6 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21283.1 - 7.8e-29 98.3 1.4 1.8e-06 27.5 0.2 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21283.1 - 2.8e-28 95.7 0.1 6e-05 22.9 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 OEU21283.1 - 1.3e-21 75.7 0.7 1.4e-05 24.8 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21283.1 - 1.1e-19 69.0 1.2 0.013 15.7 0.1 6.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OEU21283.1 - 1.9e-13 49.4 4.9 0.041 13.9 0.1 6.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 OEU21283.1 - 1.7e-08 34.0 2.5 0.0051 16.5 0.0 4.9 4 1 1 5 5 4 3 TPR repeat TPR_16 PF13432.6 OEU21283.1 - 9.6e-08 32.6 1.9 0.0002 21.9 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21283.1 - 2.2e-07 31.1 4.2 12 6.7 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21283.1 - 6.7e-07 29.6 0.4 0.78 10.7 0.0 5.3 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU21283.1 - 0.00011 21.7 0.2 0.0074 15.7 0.0 3.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OEU21283.1 - 0.00012 22.5 0.1 1.8 9.1 0.3 4.1 3 2 2 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU21283.1 - 0.00018 20.9 3.0 0.29 10.6 0.1 3.4 3 0 0 3 3 3 2 SHNi-TPR ANAPC3 PF12895.7 OEU21283.1 - 0.00052 20.2 2.7 1.4 9.2 0.1 4.5 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 OEU21283.1 - 0.00072 19.1 0.5 0.094 12.1 0.1 2.7 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP PPR PF01535.20 OEU21283.1 - 0.00089 19.4 1.9 29 5.2 0.0 4.8 5 0 0 5 5 5 0 PPR repeat TPR_9 PF13371.6 OEU21283.1 - 0.0013 18.8 1.0 0.015 15.4 0.3 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OEU21283.1 - 0.015 15.6 5.7 0.42 11.1 0.3 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OEU21283.1 - 0.031 14.3 3.5 2.6 8.2 0.1 4.3 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Rhodanese PF00581.20 OEU21285.1 - 8.4e-13 48.8 0.0 2e-05 25.1 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain STAS PF01740.21 OEU21287.1 - 1.7e-09 37.3 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 OEU21287.1 - 0.0027 16.5 9.0 0.14 10.8 4.0 2.5 2 1 0 2 2 2 2 Sulfate permease family STAS_2 PF13466.6 OEU21287.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 STAS domain HSF_DNA-bind PF00447.17 OEU21288.1 - 9.1e-06 26.2 0.0 2.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 HSF-type DNA-binding Herpes_LMP1 PF05297.11 OEU21288.1 - 0.02 14.1 2.0 0.032 13.4 2.0 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ferritin PF00210.24 OEU21289.1 - 0.0097 15.8 0.1 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 Ferritin-like domain Inhibitor_I29 PF08246.12 OEU21290.1 - 1.1e-11 45.0 6.1 0.0023 18.3 0.3 4.5 4 0 0 4 4 4 3 Cathepsin propeptide inhibitor domain (I29) ALIX_LYPXL_bnd PF13949.6 OEU21291.1 - 0.00055 19.3 2.5 0.00055 19.3 2.5 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Inhibitor_I29 PF08246.12 OEU21291.1 - 0.014 15.8 0.5 0.031 14.7 0.1 1.9 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Tmemb_cc2 PF10267.9 OEU21291.1 - 0.13 11.3 12.2 0.049 12.8 9.8 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ly49 PF08391.10 OEU21291.1 - 0.18 12.2 1.6 0.43 10.9 1.6 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Inhibitor_I29 PF08246.12 OEU21292.1 - 1.2e-07 32.0 1.4 3.3e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 Cathepsin propeptide inhibitor domain (I29) Inhibitor_I29 PF08246.12 OEU21294.1 - 3.1e-05 24.3 0.1 0.0001 22.7 0.1 2.0 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3449 PF11931.8 OEU21295.1 - 7.6e-63 211.6 0.6 8.7e-63 211.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Glyco_hydro_67C PF07477.12 OEU21295.1 - 0.032 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus MatE PF01554.18 OEU21296.1 - 7e-26 90.8 18.0 2.1e-19 69.8 5.2 3.2 3 1 1 4 4 4 2 MatE TPR_16 PF13432.6 OEU21296.1 - 0.19 12.4 0.0 1 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Mu-like_Pro PF10123.9 OEU21297.1 - 0.00054 19.6 0.1 2.9 7.4 0.0 3.0 3 0 0 3 3 3 3 Mu-like prophage I protein CBM53 PF16760.5 OEU21297.1 - 3.3 8.4 6.3 2.2 8.9 0.3 3.3 3 0 0 3 3 3 0 Starch/carbohydrate-binding module (family 53) Utp21 PF04192.12 OEU21299.1 - 5.8e-37 127.4 0.3 1.1e-36 126.6 0.3 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 OEU21299.1 - 6.2e-11 42.7 10.3 1.3e-05 25.9 0.3 6.9 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU21299.1 - 1.2e-09 38.3 0.0 0.005 17.1 0.0 4.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OEU21299.1 - 0.051 12.2 0.0 0.11 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OEU21299.1 - 0.076 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Syntaxin PF00804.25 OEU21300.1 - 2.5e-07 30.6 8.0 1.3e-06 28.2 2.3 2.2 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 OEU21300.1 - 8.9e-06 25.6 4.4 0.017 15.1 0.2 2.5 2 0 0 2 2 2 2 SNARE domain SF-assemblin PF06705.11 OEU21300.1 - 0.02 14.3 7.6 0.3 10.4 1.8 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin Syntaxin_2 PF14523.6 OEU21300.1 - 0.039 14.3 10.6 1.7 9.1 4.9 2.5 2 0 0 2 2 2 0 Syntaxin-like protein V-SNARE PF05008.15 OEU21300.1 - 0.043 14.2 4.5 2.4 8.6 0.6 3.2 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus RmuC PF02646.16 OEU21300.1 - 0.054 12.6 6.2 0.65 9.1 1.7 2.4 2 0 0 2 2 2 0 RmuC family Apolipoprotein PF01442.18 OEU21300.1 - 0.057 13.3 7.4 0.33 10.8 1.2 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain XhlA PF10779.9 OEU21300.1 - 0.06 13.6 3.1 3.3 8.0 0.1 2.8 2 0 0 2 2 2 0 Haemolysin XhlA HeLo PF14479.6 OEU21300.1 - 0.06 13.2 2.0 0.16 11.8 0.1 2.3 2 1 0 2 2 2 0 Prion-inhibition and propagation Baculo_PEP_C PF04513.12 OEU21300.1 - 0.074 13.1 11.7 0.12 12.4 2.1 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OEU21300.1 - 0.28 10.0 7.4 1.2 8.0 2.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Sulfatase_C PF14707.6 OEU21300.1 - 0.34 11.7 0.7 46 4.8 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF1664 PF07889.12 OEU21300.1 - 0.4 10.7 9.0 8.1 6.5 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OEU21300.1 - 0.45 10.5 7.9 2.4 8.2 0.9 2.6 2 1 1 3 3 3 0 Laminin Domain II Filament PF00038.21 OEU21300.1 - 0.47 10.0 9.3 1.7 8.2 1.8 2.1 2 0 0 2 2 2 0 Intermediate filament protein Rx_N PF18052.1 OEU21300.1 - 0.64 10.3 3.2 5.7 7.3 0.2 2.4 2 0 0 2 2 2 0 Rx N-terminal domain SKA1 PF07160.12 OEU21300.1 - 0.93 9.3 7.2 0.63 9.8 1.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF5082 PF16888.5 OEU21300.1 - 0.96 9.7 4.7 17 5.7 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Seryl_tRNA_N PF02403.22 OEU21300.1 - 1 9.6 7.8 0.28 11.4 2.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 OEU21300.1 - 1 9.4 7.7 6.2 6.9 2.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 OEU21300.1 - 1.3 8.8 8.8 4.8 6.9 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) WEMBL PF05701.11 OEU21300.1 - 1.8 7.2 8.1 0.6 8.7 1.8 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.12 OEU21300.1 - 2 8.5 6.0 25 4.9 0.9 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 OEU21300.1 - 2.1 8.5 10.3 3.6 7.8 1.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 OEU21300.1 - 3.1 8.1 10.2 6.4 7.1 0.9 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nup88 PF10168.9 OEU21300.1 - 3.6 5.3 7.0 0.28 9.0 2.4 1.3 2 0 0 2 2 2 0 Nuclear pore component DUF883 PF05957.13 OEU21300.1 - 3.7 8.2 5.2 6.5 7.4 0.8 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TMF_TATA_bd PF12325.8 OEU21300.1 - 4.4 7.5 9.5 0.76 10.0 0.9 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 OEU21300.1 - 4.5 7.8 10.0 2.1 8.9 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 OEU21300.1 - 8.2 5.6 6.5 9.6 5.3 1.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein Corazonin PF17308.2 OEU21301.1 - 0.011 16.1 6.8 3.7 7.9 0.5 3.3 3 0 0 3 3 3 0 Pro-corazonin NUDIX PF00293.28 OEU21302.1 - 0.013 15.6 0.0 0.042 13.9 0.0 1.9 1 0 0 1 1 1 0 NUDIX domain ATP-grasp_3 PF02655.14 OEU21303.1 - 0.019 15.0 0.0 0.22 11.5 0.0 2.5 3 0 0 3 3 3 0 ATP-grasp domain bZIP_2 PF07716.15 OEU21303.1 - 0.12 12.4 0.3 0.47 10.6 0.2 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DUF4280 PF14107.6 OEU21303.1 - 0.13 13.1 0.2 0.71 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4280) DivIC PF04977.15 OEU21303.1 - 0.33 10.8 0.9 0.91 9.3 0.9 1.7 1 0 0 1 1 1 0 Septum formation initiator SGT1 PF07093.11 OEU21304.1 - 1.2e-22 80.1 7.3 4.9e-21 74.8 0.1 2.6 3 0 0 3 3 3 2 SGT1 protein MaoC_dehydratas PF01575.19 OEU21305.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain CS PF04969.16 OEU21306.1 - 1.8e-06 28.9 0.1 2.7e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF4843 PF16132.5 OEU21306.1 - 0.057 13.0 0.4 0.077 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) DUF1654 PF07867.11 OEU21306.1 - 0.11 12.2 0.8 0.19 11.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) LRR_6 PF13516.6 OEU21307.1 - 3.3e-41 135.8 61.4 7.4e-06 25.6 0.7 15.2 15 0 0 15 15 15 12 Leucine Rich repeat LRR_4 PF12799.7 OEU21307.1 - 8.3e-13 48.3 58.6 6.4e-05 23.2 1.1 10.3 4 3 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU21307.1 - 3.2e-05 23.6 57.3 0.011 15.5 3.4 10.8 6 4 3 9 9 9 6 Leucine rich repeat LRR_1 PF00560.33 OEU21307.1 - 4.1e-05 23.5 29.5 25 5.9 0.1 13.8 15 1 0 15 15 15 1 Leucine Rich Repeat Nucleic_acid_bd PF13820.6 OEU21307.1 - 0.016 15.0 1.9 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 Putative nucleic acid-binding region YjeF_N PF03853.15 OEU21308.1 - 5.7e-35 120.7 0.0 7.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus TIM21 PF08294.11 OEU21309.1 - 1.5e-11 44.4 0.2 2.5e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 TIM21 HEAT PF02985.22 OEU21310.1 - 2.3e-32 108.3 32.4 6.6e-05 22.8 0.0 13.2 14 0 0 14 14 14 7 HEAT repeat HEAT_2 PF13646.6 OEU21310.1 - 5.2e-26 90.9 21.7 3.6e-08 33.7 0.0 6.7 4 1 3 7 7 7 7 HEAT repeats Cnd1 PF12717.7 OEU21310.1 - 3.3e-11 43.5 1.4 0.018 15.1 0.1 4.7 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OEU21310.1 - 2.9e-10 40.6 0.0 0.11 13.1 0.0 5.6 4 3 0 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OEU21310.1 - 2.4e-09 37.5 18.3 0.083 13.4 0.0 8.6 6 3 3 9 9 9 2 HEAT-like repeat IFRD PF05004.13 OEU21310.1 - 0.00046 19.4 0.5 0.6 9.2 0.2 3.5 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 OEU21310.1 - 0.022 13.3 0.3 0.24 9.9 0.0 2.4 1 1 0 2 2 2 0 Adaptin N terminal region DUF4042 PF13251.6 OEU21310.1 - 0.061 13.0 0.6 7.2 6.3 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Cupin_3 PF05899.12 OEU21311.1 - 9.8e-16 57.2 0.4 1.1e-15 57.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OEU21311.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OEU21311.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.0 1 0 0 1 1 1 0 Cupin HutD PF05962.11 OEU21311.1 - 0.2 11.6 0.0 0.21 11.6 0.0 1.0 1 0 0 1 1 1 0 HutD Pkinase PF00069.25 OEU21312.1 - 1.9e-49 168.4 0.0 3.8e-49 167.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21312.1 - 4.4e-36 124.5 0.0 5.6e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU21312.1 - 8.1e-05 22.1 0.0 0.00017 21.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OEU21312.1 - 0.0025 17.8 0.7 0.09 12.7 0.3 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OEU21312.1 - 0.045 13.1 2.2 0.045 13.1 0.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OEU21312.1 - 0.058 12.9 1.6 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OEU21312.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF4518 PF15008.6 OEU21314.1 - 0.13 11.4 2.6 0.12 11.5 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) GST_C_3 PF14497.6 OEU21315.1 - 5.4e-12 45.8 1.3 1.1e-11 44.7 0.5 1.9 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU21315.1 - 7.9e-07 29.3 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU21315.1 - 0.0019 18.6 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU21315.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OEU21315.1 - 0.021 15.1 0.0 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU21315.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Nucleoporin_FG PF13634.6 OEU21316.1 - 4.4e-23 81.9 117.1 5.8e-10 39.9 14.6 7.1 2 2 4 6 6 6 6 Nucleoporin FG repeat region DUF1664 PF07889.12 OEU21316.1 - 0.83 9.7 5.7 11 6.0 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OEU21316.1 - 1.2 9.3 4.4 20 5.4 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NleF_casp_inhib PF16809.5 OEU21316.1 - 3.1 7.7 5.7 0.87 9.5 2.0 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor NADH-G_4Fe-4S_3 PF10588.9 OEU21317.1 - 0.48 10.0 2.7 1.2 8.7 2.7 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Pkinase PF00069.25 OEU21318.1 - 8.5e-54 182.7 0.0 1.2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21318.1 - 1e-31 110.2 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 OEU21318.1 - 1.2e-19 70.1 0.1 2e-18 66.3 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Kinase-like PF14531.6 OEU21318.1 - 0.0026 17.1 0.0 0.0078 15.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OEU21318.1 - 0.0029 17.6 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_Tnp_1_7 PF13843.6 OEU21319.1 - 0.00013 21.4 0.2 0.16 11.3 0.7 3.1 2 1 0 2 2 2 2 Transposase IS4 IL17 PF06083.11 OEU21320.1 - 0.09 13.3 0.8 4.3 7.9 1.0 3.0 2 0 0 2 2 2 0 Interleukin-17 SIN1 PF05422.12 OEU21320.1 - 0.52 10.9 4.8 1.2 9.6 4.8 1.6 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) IQ PF00612.27 OEU21320.1 - 0.98 9.4 6.4 0.1 12.5 0.3 2.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif HECT PF00632.25 OEU21321.1 - 2.4e-89 299.8 0.0 2.8e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DnaJ PF00226.31 OEU21322.1 - 5.1e-07 29.7 0.0 9.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L31e PF01198.19 OEU21323.1 - 3.7e-40 136.0 0.6 4.5e-40 135.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_L41 PF05162.13 OEU21323.1 - 0.18 11.9 0.6 0.18 11.9 0.6 2.2 2 0 0 2 2 2 0 Ribosomal protein L41 Pkinase PF00069.25 OEU21324.1 - 7.3e-46 156.7 0.0 1e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21324.1 - 1.7e-28 99.6 0.0 2e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 OEU21324.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 OEU21324.1 - 0.027 13.8 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Spermine_synth PF01564.17 OEU21325.1 - 8.2e-42 142.7 0.0 1.2e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OEU21325.1 - 1.2e-13 50.7 0.3 2.8e-13 49.5 0.3 1.7 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OEU21325.1 - 3.6e-05 24.4 0.0 0.00027 21.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU21325.1 - 0.00061 20.4 0.0 0.0015 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU21325.1 - 0.0062 17.2 0.0 0.021 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Eno-Rase_NADH_b PF12242.8 OEU21325.1 - 0.035 13.9 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_23 PF13489.6 OEU21325.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain PHD PF00628.29 OEU21326.1 - 2.9e-09 36.7 9.1 6.9e-09 35.5 9.1 1.6 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 OEU21326.1 - 0.00051 20.3 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 DDT domain Prok-RING_1 PF14446.6 OEU21326.1 - 0.036 14.0 4.1 0.11 12.5 4.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 WHIM1 PF15612.6 OEU21326.1 - 0.15 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 OEU21326.1 - 0.29 10.7 3.5 0.72 9.5 3.5 1.7 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 OEU21326.1 - 3 8.0 8.4 29 4.8 8.4 2.8 1 1 0 1 1 1 0 PHD-finger Pkinase PF00069.25 OEU21327.1 - 1.5e-41 142.6 0.0 1.6e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21327.1 - 4.4e-12 45.8 0.0 6.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU21327.1 - 0.00019 21.4 0.1 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU21327.1 - 0.0036 16.1 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OEU21327.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OEU21327.1 - 0.032 13.2 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OEU21327.1 - 0.051 12.9 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cyt-b5 PF00173.28 OEU21328.1 - 1.8e-13 50.4 0.2 2e-13 50.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ArfGap PF01412.18 OEU21329.1 - 5.5e-26 90.9 2.1 5.9e-26 90.8 2.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ERM PF00769.19 OEU21331.1 - 0.0037 17.1 3.0 0.0058 16.5 3.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family GLYCAM-1 PF05242.11 OEU21331.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.0 2 1 1 3 3 3 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) APG6_N PF17675.1 OEU21331.1 - 1.1 9.8 6.7 1.8 9.1 6.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_14 PF13428.6 OEU21332.1 - 1.6e-09 37.8 14.3 0.055 14.3 0.1 10.0 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21332.1 - 1.1e-06 28.3 4.2 0.024 14.7 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 OEU21332.1 - 3.4e-06 26.5 5.5 0.033 13.4 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OEU21332.1 - 4.2e-05 23.6 7.8 0.0004 20.5 0.1 4.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21332.1 - 0.00017 21.6 3.3 1.4 9.3 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU21332.1 - 0.00027 20.8 2.0 0.025 14.6 0.0 4.6 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21332.1 - 0.00031 21.2 4.2 0.48 11.0 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU21332.1 - 0.0021 18.3 0.7 15 5.9 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OEU21332.1 - 0.0036 16.5 9.8 0.061 12.4 0.5 4.5 3 2 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 OEU21332.1 - 0.0078 16.5 4.5 0.12 12.8 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 OEU21332.1 - 0.016 15.2 1.1 4.6 7.1 0.0 4.3 4 1 1 5 5 5 0 Suppressor of forked protein (Suf) TPR_10 PF13374.6 OEU21332.1 - 0.028 14.3 1.2 11 6.1 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21332.1 - 0.028 15.1 5.6 6.2 7.6 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21332.1 - 0.23 11.4 7.0 3.8 7.5 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21332.1 - 0.45 11.3 8.1 8.4 7.3 0.2 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 OEU21332.1 - 0.74 8.7 5.6 1.4 7.8 0.0 2.6 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Exo70 PF03081.15 OEU21333.1 - 2.4e-27 96.0 1.6 2.9e-27 95.7 1.6 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit COG6 PF06419.11 OEU21333.1 - 0.056 11.6 0.0 0.056 11.6 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 EXS PF03124.14 OEU21334.1 - 1.9e-53 181.9 14.7 3.5e-53 181.1 14.7 1.4 1 1 0 1 1 1 1 EXS family zf-LITAF-like PF10601.9 OEU21334.1 - 0.047 14.0 1.2 6.7 7.1 0.0 3.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain EPTP PF03736.17 OEU21334.1 - 0.075 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 EPTP domain Spermine_synth PF01564.17 OEU21335.1 - 1.1e-16 60.8 0.1 1.3e-16 60.6 0.1 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF4183 PF13799.6 OEU21335.1 - 0.057 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) Methyltransf_25 PF13649.6 OEU21335.1 - 0.088 13.5 0.0 0.15 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AdoMet_dc PF02675.15 OEU21336.1 - 2.7e-22 79.0 0.0 3e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase SET PF00856.28 OEU21338.1 - 2.1e-12 47.7 0.0 6.4e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OEU21338.1 - 1e-08 35.1 12.3 1e-08 35.1 12.3 3.5 3 1 0 3 3 3 1 MYND finger Methyltransf_16 PF10294.9 OEU21339.1 - 7.6e-16 58.3 1.3 2e-13 50.4 1.3 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 OEU21339.1 - 0.097 12.7 0.9 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 OEU21339.1 - 0.11 12.1 0.2 0.35 10.4 0.1 1.8 1 1 1 2 2 2 0 Methyltransferase small domain SR-25 PF10500.9 OEU21339.1 - 1.7 8.2 9.0 0.18 11.4 1.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DnaJ PF00226.31 OEU21340.1 - 1e-12 47.9 0.9 4.2e-12 46.0 0.9 2.1 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L1 PF00687.21 OEU21341.1 - 1.6e-49 168.4 0.3 1.6e-49 168.4 0.3 1.6 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family USP19_linker PF16602.5 OEU21341.1 - 0.016 15.7 1.6 4.2 8.0 1.6 2.4 1 1 0 1 1 1 0 Linker region of USP19 deubiquitinase MFS_1 PF07690.16 OEU21342.1 - 1.4e-24 86.7 23.8 6e-18 64.9 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU21342.1 - 0.17 10.7 22.1 0.044 12.6 9.5 3.0 2 1 0 2 2 2 0 Sugar (and other) transporter RHH_6 PF16762.5 OEU21343.1 - 0.011 16.3 0.2 4.7 7.9 0.0 2.9 2 1 0 2 2 2 0 Ribbon-helix-helix domain Phg_2220_C PF09524.10 OEU21343.1 - 0.19 11.8 1.6 2.6 8.2 0.0 3.2 2 2 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Glyco_hydro_28 PF00295.17 OEU21344.1 - 5.2e-41 140.8 0.1 7.6e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 OEU21344.1 - 5.4e-13 49.3 3.9 1.3e-11 44.8 0.1 2.7 1 1 1 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OEU21344.1 - 0.35 10.6 1.4 0.57 9.9 0.1 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Disaggr_assoc PF08480.10 OEU21344.1 - 1.3 8.9 6.4 0.95 9.3 1.8 2.2 1 1 1 2 2 2 0 Disaggregatase related Fe-ADH PF00465.19 OEU21346.1 - 2.4e-09 36.5 0.0 3.9e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OEU21346.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ANAPC4_WD40 PF12894.7 OEU21347.1 - 2.8e-25 88.4 4.3 0.0036 17.6 0.0 10.2 2 2 9 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OEU21347.1 - 6.1e-14 52.2 15.3 0.33 11.9 0.0 10.2 11 1 0 11 11 10 3 WD domain, G-beta repeat eIF2A PF08662.11 OEU21347.1 - 2.5e-10 40.6 4.9 0.025 14.5 0.0 5.2 5 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OEU21347.1 - 1e-06 28.5 8.2 0.47 10.5 0.0 5.4 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 OEU21347.1 - 0.00015 21.0 1.4 2.8 6.9 0.0 4.3 3 2 0 4 4 4 2 Coatomer WD associated region Cytochrom_D1 PF02239.16 OEU21347.1 - 0.00049 18.7 1.5 0.23 10.0 0.2 3.5 2 1 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 OEU21347.1 - 0.03 13.6 1.1 8.9 5.5 0.1 3.4 3 0 0 3 3 3 0 WD40-like domain TFIIIC_delta PF12657.7 OEU21347.1 - 0.044 13.7 5.0 8.2 6.3 0.0 4.5 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PAS_2 PF08446.11 OEU21347.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold Proteasome_A_N PF10584.9 OEU21347.1 - 0.15 11.7 0.0 28 4.5 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature IKI3 PF04762.12 OEU21347.1 - 1.9 6.4 5.4 12 3.7 0.2 3.8 3 2 0 3 3 3 0 IKI3 family Sulfatase PF00884.23 OEU21348.1 - 6.8e-60 203.1 0.0 2e-59 201.5 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OEU21348.1 - 1.1e-16 61.7 0.1 2.1e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OEU21348.1 - 0.028 14.0 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase KOW PF00467.29 OEU21349.1 - 3.7e-15 55.3 22.2 0.00027 20.8 2.1 7.1 7 0 0 7 7 7 5 KOW motif Spt5-NGN PF03439.13 OEU21349.1 - 7.4e-14 51.4 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 OEU21349.1 - 0.024 14.9 3.2 8.6 6.7 0.1 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3912) MDMPI_C PF07398.11 OEU21349.1 - 3.8 8.4 6.1 3.3 8.6 1.0 2.6 2 0 0 2 2 2 0 MDMPI C-terminal domain WD40 PF00400.32 OEU21350.1 - 2.8e-27 94.4 5.5 2.8e-09 37.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU21350.1 - 1.1e-09 38.5 0.0 0.049 13.9 0.0 4.8 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU21350.1 - 3.7e-05 22.8 0.0 0.086 11.8 0.0 2.9 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OEU21350.1 - 0.056 13.4 0.0 5.8 7.0 0.0 3.4 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 OEU21350.1 - 0.059 13.4 0.0 16 5.6 0.0 3.2 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region AdoMet_dc PF02675.15 OEU21352.1 - 3.6e-23 81.8 0.2 4e-23 81.7 0.2 1.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Spermine_synth PF01564.17 OEU21353.1 - 1.5e-28 99.5 0.0 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 OEU21353.1 - 3.1e-05 23.8 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OEU21353.1 - 0.00028 21.6 0.0 0.0012 19.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21353.1 - 0.00044 20.9 0.0 0.0018 18.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OEU21353.1 - 0.045 13.5 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 OEU21353.1 - 0.047 14.3 0.0 0.21 12.3 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 OEU21353.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Csm1_N PF18504.1 OEU21354.1 - 0.0096 16.2 3.7 0.0096 16.2 3.7 12.3 10 4 5 15 15 15 1 Csm1 N-terminal domain POPLD PF08170.12 OEU21354.1 - 3.2 8.2 4.2 15 6.1 4.2 2.2 1 0 0 1 1 1 0 POPLD (NUC188) domain Gtr1_RagA PF04670.12 OEU21355.1 - 1.8e-54 184.5 0.0 2.6e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU21355.1 - 0.004 17.2 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OEU21355.1 - 0.012 15.8 0.0 0.091 13.0 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NifT PF06988.11 OEU21355.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NifT/FixU protein AAA_14 PF13173.6 OEU21355.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAST_1 PF06743.15 OEU21355.1 - 0.16 11.9 0.1 0.48 10.4 0.1 1.8 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Ureide_permease PF07168.11 OEU21356.1 - 0.078 11.7 0.0 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 Ureide permease Neugrin PF06413.11 OEU21356.1 - 0.097 12.7 5.2 4.3 7.3 0.3 2.4 1 1 1 2 2 2 0 Neugrin DUF2839 PF10999.8 OEU21356.1 - 0.91 9.9 2.8 0.61 10.5 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) Flavodoxin_1 PF00258.25 OEU21357.1 - 2.5e-17 63.4 0.0 2.7e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.11 OEU21357.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 NrdI Flavodoxin like NAD_binding_1 PF00175.21 OEU21358.1 - 8e-09 36.1 0.0 1.2e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2228 PF10228.9 OEU21358.1 - 0.023 14.4 0.2 0.18 11.5 0.2 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) CS PF04969.16 OEU21359.1 - 0.031 15.3 0.4 0.059 14.4 0.4 1.5 1 1 0 1 1 1 0 CS domain GST_N_3 PF13417.6 OEU21361.1 - 4.5e-07 30.2 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OEU21361.1 - 0.00032 20.8 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU21361.1 - 0.00049 20.4 0.0 0.00091 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU21361.1 - 0.00062 20.0 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OEU21361.1 - 0.0074 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OEU21361.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4672 PF15716.5 OEU21362.1 - 8 6.0 9.3 0.72 9.5 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4672) DAP_epimerase PF01678.19 OEU21363.1 - 4.9e-67 223.6 0.0 1.3e-33 115.8 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 OEU21363.1 - 4.4e-05 23.1 0.0 9.3e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Complex1_LYR PF05347.15 OEU21364.1 - 0.0004 20.4 0.0 0.00057 19.9 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2214 PF09980.9 OEU21365.1 - 1.1e-41 142.1 0.0 1.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2214) LtrA PF06772.11 OEU21365.1 - 0.062 12.5 0.0 0.76 8.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) DUF900 PF05990.12 OEU21366.1 - 3.5e-10 39.8 0.0 7.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Chitin_synth_2 PF03142.15 OEU21366.1 - 0.037 12.7 7.1 0.056 12.1 7.1 1.2 1 0 0 1 1 1 0 Chitin synthase DUF2070 PF09843.9 OEU21366.1 - 0.25 9.6 2.9 0.38 9.0 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UbiA PF01040.18 OEU21367.1 - 1.2e-19 70.6 2.4 2.4e-19 69.6 2.4 1.5 1 0 0 1 1 1 1 UbiA prenyltransferase family AWPM-19 PF05512.11 OEU21368.1 - 1.2 9.4 6.0 1.2 9.3 0.4 2.4 1 1 1 2 2 2 0 AWPM-19-like family Sigma70_r2 PF04542.14 OEU21369.1 - 1.5e-07 31.1 0.0 3.4e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 OEU21369.1 - 0.031 14.4 0.0 0.031 14.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 CDC45 PF02724.14 OEU21369.1 - 0.16 10.3 2.4 0.18 10.1 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OEU21369.1 - 3.5 5.6 11.4 5.3 5.0 11.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 OEU21369.1 - 6.4 6.1 10.5 8.8 5.6 10.5 1.2 1 0 0 1 1 1 0 SDA1 Condensin2nSMC PF12422.8 OEU21370.1 - 2.2e-41 141.5 1.9 2.3e-40 138.2 0.1 3.5 3 1 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 OEU21370.1 - 4.7e-05 23.3 7.7 1.1 9.7 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.8 OEU21370.1 - 0.00019 21.1 1.9 1.4 8.4 0.1 4.1 2 1 2 4 4 4 3 CLASP N terminal HEAT_2 PF13646.6 OEU21370.1 - 0.00023 21.5 6.9 0.13 12.7 0.7 3.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 OEU21370.1 - 0.00074 19.6 2.5 1.1 9.3 0.0 4.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OEU21370.1 - 0.055 14.0 7.9 0.5 10.9 0.8 4.2 4 0 0 4 4 4 0 HEAT-like repeat DUF4519 PF15012.6 OEU21370.1 - 9.4 6.5 6.1 28 5.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Fer2_4 PF13510.6 OEU21371.1 - 0.058 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain GvpL_GvpF PF06386.11 OEU21372.1 - 0.54 10.2 3.4 0.75 9.7 3.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ORC6 PF05460.13 OEU21373.1 - 1.9 7.7 14.3 2.5 7.3 14.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SBF2 PF12335.8 OEU21373.1 - 5.8 6.4 6.3 1.5 8.4 3.1 1.6 2 0 0 2 2 2 0 Myotubularin protein Presenilin PF01080.17 OEU21373.1 - 8.4 5.0 10.1 10 4.8 10.1 1.3 1 0 0 1 1 1 0 Presenilin Fructosamin_kin PF03881.14 OEU21374.1 - 9.7e-74 248.2 0.0 1.2e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase CRAL_TRIO PF00650.20 OEU21376.1 - 1e-24 87.1 0.0 1.8e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OEU21376.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Thi4 PF01946.17 OEU21377.1 - 0.00047 19.5 0.0 0.01 15.1 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OEU21377.1 - 0.054 12.7 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CENP-B_dimeris PF09026.10 OEU21378.1 - 3.7 8.0 7.3 1.5 9.3 1.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Borrelia_P13 PF05628.12 OEU21379.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 FKBP_C PF00254.28 OEU21380.1 - 6.6e-19 68.0 0.0 9.8e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MTS PF05175.14 OEU21381.1 - 1.8e-12 47.1 0.0 3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OEU21381.1 - 3.5e-11 43.1 0.0 2e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU21381.1 - 7.7e-11 41.9 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OEU21381.1 - 1.3e-07 32.2 0.0 4.3e-07 30.6 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain PrmC_N PF17827.1 OEU21381.1 - 2e-06 28.3 0.3 4e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_16 PF10294.9 OEU21381.1 - 1.5e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 OEU21381.1 - 0.00018 22.2 0.0 0.00054 20.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU21381.1 - 0.00035 20.6 0.0 0.00055 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21381.1 - 0.00079 19.3 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU21381.1 - 0.0077 16.9 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OEU21381.1 - 0.019 14.5 0.3 0.042 13.3 0.1 1.7 2 0 0 2 2 2 0 Putative methyltransferase Cons_hypoth95 PF03602.15 OEU21381.1 - 0.028 14.1 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 OEU21381.1 - 0.031 14.2 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OEU21381.1 - 0.047 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 OEU21381.1 - 0.12 12.0 1.6 0.48 10.1 1.6 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.19 OEU21381.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_Mtase PF02384.16 OEU21381.1 - 0.17 11.1 0.2 0.54 9.5 0.2 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase Pkinase PF00069.25 OEU21382.1 - 2e-39 135.5 0.0 2.2e-38 132.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21382.1 - 1.6e-24 86.6 0.0 5.4e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OEU21382.1 - 4.1e-05 23.0 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OEU21382.1 - 0.002 17.8 0.1 0.87 9.2 0.1 2.5 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 OEU21382.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 OEU21382.1 - 0.12 11.8 0.5 0.32 10.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4 PF00097.25 OEU21383.1 - 1.2e-08 34.7 1.4 1.2e-08 34.7 1.4 2.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU21383.1 - 5.9e-08 32.4 2.1 5.9e-08 32.4 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU21383.1 - 4e-07 29.9 3.0 4e-07 29.9 3.0 2.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU21383.1 - 3.6e-06 26.7 1.6 3.6e-06 26.7 1.6 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU21383.1 - 5.2e-06 26.5 1.8 5.2e-06 26.5 1.8 2.2 1 1 2 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OEU21383.1 - 6.4e-06 26.0 2.4 6.4e-06 26.0 2.4 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OEU21383.1 - 1.4e-05 25.3 3.9 1.4e-05 25.3 3.9 2.1 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OEU21383.1 - 0.022 14.6 2.5 0.022 14.6 2.5 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OEU21383.1 - 6 7.2 12.9 0.32 11.3 4.9 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain MCM PF00493.23 OEU21385.1 - 9.6e-95 315.9 0.0 1.4e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OEU21385.1 - 2.4e-31 108.2 1.0 5e-31 107.2 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OEU21385.1 - 1.2e-27 96.1 0.6 2.6e-27 95.1 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OEU21385.1 - 9.7e-05 21.8 0.0 0.00029 20.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OEU21385.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU21385.1 - 0.0085 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 OEU21385.1 - 0.17 12.5 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Menin PF05053.13 OEU21385.1 - 0.27 9.5 2.8 0.4 9.0 2.8 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 OEU21385.1 - 7.7 7.1 19.9 2.2 8.9 15.9 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain TspO_MBR PF03073.15 OEU21386.1 - 3.4e-29 101.6 17.5 3.8e-29 101.4 17.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Isy1 PF06246.12 OEU21387.1 - 7.5e-59 199.4 4.8 8.4e-59 199.2 4.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Val_tRNA-synt_C PF10458.9 OEU21387.1 - 0.06 13.6 0.8 0.2 11.9 0.8 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Surp PF01805.20 OEU21388.1 - 5.7e-27 93.5 0.0 6.3e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 OEU21388.1 - 7.6e-26 91.3 0.3 7.6e-26 91.3 0.3 3.8 3 2 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 OEU21388.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family ThiC-associated PF13667.6 OEU21388.1 - 0.028 14.2 4.0 1.5 8.7 0.2 2.7 2 0 0 2 2 2 0 ThiC-associated domain PQ-loop PF04193.14 OEU21389.1 - 8.9e-10 38.2 1.6 1.3e-09 37.7 1.6 1.2 1 0 0 1 1 1 1 PQ loop repeat TMEM154 PF15102.6 OEU21389.1 - 0.019 14.8 0.2 0.026 14.4 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF1139 PF06599.11 OEU21390.1 - 0.037 13.4 0.6 0.05 13.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1139) SKA1 PF07160.12 OEU21390.1 - 0.25 11.2 6.9 0.33 10.8 6.9 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PqiA PF04403.13 OEU21392.1 - 2.5e-13 50.1 32.8 2.4e-11 43.7 7.4 3.7 3 1 1 4 4 4 2 Paraquat-inducible protein A DUF5316 PF17247.2 OEU21392.1 - 0.42 10.7 4.1 0.14 12.2 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5316) MIF4G_like_2 PF09090.11 OEU21393.1 - 0.12 11.9 0.7 0.19 11.2 0.1 1.5 2 0 0 2 2 2 0 MIF4G like ECH_1 PF00378.20 OEU21394.1 - 4.5e-28 98.2 0.0 5.4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU21394.1 - 5.9e-12 45.7 0.0 7.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CinA PF02464.17 OEU21396.1 - 1.5e-17 63.6 0.0 2.1e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 Competence-damaged protein DUF3782 PF12644.7 OEU21396.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Gryzun-like PF12742.7 OEU21397.1 - 0.0059 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking NifU PF01106.17 OEU21399.1 - 2e-27 95.2 0.1 3.6e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 OEU21399.1 - 7.8e-27 93.2 0.2 1.9e-26 91.9 0.2 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal KTI12 PF08433.10 OEU21399.1 - 0.017 14.6 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Acid_PPase PF12689.7 OEU21400.1 - 1.3e-42 145.5 6.8 2.1e-41 141.6 6.8 2.7 1 1 0 1 1 1 1 Acid Phosphatase PhnI PF05861.12 OEU21400.1 - 0.033 13.0 0.1 0.046 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) SPT6_acidic PF14632.6 OEU21400.1 - 0.37 11.4 24.0 0.043 14.4 7.8 3.2 3 0 0 3 3 3 0 Acidic N-terminal SPT6 DUF1754 PF08555.10 OEU21400.1 - 0.55 11.1 23.1 0.11 13.4 13.8 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Neuraminidase PF18413.1 OEU21400.1 - 3 7.5 16.1 1.3 8.6 0.7 3.0 1 1 2 3 3 3 0 Neuraminidase-like domain LNS2 PF08235.13 OEU21402.1 - 2.9e-38 131.6 0.1 3.8e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) 5-nucleotidase PF06189.12 OEU21402.1 - 0.063 12.2 0.0 0.16 10.9 0.0 1.5 1 1 1 2 2 2 0 5'-nucleotidase PseudoU_synth_2 PF00849.22 OEU21403.1 - 3.1e-10 40.4 13.1 8.9e-08 32.4 0.1 3.3 2 1 0 2 2 2 2 RNA pseudouridylate synthase Phostensin PF13914.6 OEU21403.1 - 3.1 8.4 9.5 1.7 9.3 3.5 2.4 1 1 1 2 2 2 0 Phostensin PP1-binding and SH3-binding region CSRNP_N PF16019.5 OEU21403.1 - 7.7 6.4 16.7 0.22 11.4 9.3 2.1 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus LRR_6 PF13516.6 OEU21404.1 - 2.2e-09 36.6 13.9 0.00018 21.3 0.1 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_8 PF13855.6 OEU21404.1 - 0.00067 19.4 3.3 5.3 6.9 0.1 4.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 OEU21404.1 - 0.096 13.3 17.1 6.3 7.8 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 OEU21405.1 - 1.9e-07 30.7 4.9 1.9e-07 30.7 4.9 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OEU21405.1 - 1.4e-05 25.3 7.5 0.012 16.0 6.8 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU21405.1 - 0.21 12.2 5.7 3 8.7 0.1 3.4 2 1 0 2 2 2 0 Leucine Rich Repeat HA PF03457.14 OEU21406.1 - 9.5e-35 118.7 1.9 1.5e-18 66.9 0.2 2.0 2 0 0 2 2 2 2 Helicase associated domain AP2 PF00847.20 OEU21406.1 - 0.011 15.9 0.5 4 7.7 0.1 2.4 2 0 0 2 2 2 0 AP2 domain VAPB_antitox PF02697.14 OEU21406.1 - 0.03 15.1 0.1 6.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin PseudoU_synth_2 PF00849.22 OEU21408.1 - 8.8e-23 81.2 0.9 2.2e-22 79.8 0.0 2.1 2 1 0 2 2 2 1 RNA pseudouridylate synthase BAG6 PF12057.8 OEU21408.1 - 0.25 11.0 1.4 0.76 9.5 0.2 2.4 2 0 0 2 2 2 0 BCL2-associated athanogene 6 Glyco_hyd_101C PF17451.2 OEU21409.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Pyridoxal_deC PF00282.19 OEU21411.1 - 7.2e-36 123.7 0.0 1.3e-35 122.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OEU21411.1 - 6.6e-06 25.3 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OEU21411.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase HRCT1 PF15758.5 OEU21412.1 - 0.18 12.8 1.5 4.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Histidine-rich carboxyl terminus protein 1 NUDIX PF00293.28 OEU21413.1 - 1.5e-11 44.5 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain PUF PF00806.19 OEU21415.1 - 5.5e-12 44.7 1.2 0.0048 16.5 0.2 5.6 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat RRS1 PF04939.12 OEU21415.1 - 0.26 11.2 5.0 0.06 13.2 0.6 2.1 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_60s PF00428.19 OEU21415.1 - 4 8.1 0.0 4 8.1 0.0 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 OEU21415.1 - 6 7.3 15.7 0.036 14.5 4.6 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain zf-MYND PF01753.18 OEU21416.1 - 1.4e-08 34.7 12.4 3.2e-08 33.5 12.4 1.7 1 0 0 1 1 1 1 MYND finger HNHc_6 PF16784.5 OEU21416.1 - 0.0014 18.2 0.3 0.0034 17.0 0.3 1.6 1 0 0 1 1 1 1 Putative HNHc nuclease Terminase_3 PF04466.13 OEU21418.1 - 0.26 10.8 2.8 1.3 8.5 1.5 2.3 2 0 0 2 2 2 0 Phage terminase large subunit Ion_trans_2 PF07885.16 OEU21419.1 - 1.4e-14 53.8 0.9 3.3e-14 52.6 0.9 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 OEU21419.1 - 4.3e-14 52.3 3.5 7.6e-14 51.5 3.5 1.4 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 OEU21419.1 - 4e-09 35.4 1.3 0.00051 19.4 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OEU21419.1 - 7.3e-08 31.6 2.4 0.0069 15.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU21419.1 - 1.2e-06 28.9 1.9 3.1e-06 27.5 0.4 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU21419.1 - 2.8e-05 23.7 1.2 0.051 13.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OEU21419.1 - 6.7e-05 22.7 1.9 0.22 11.4 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU21419.1 - 0.0029 17.9 0.6 0.015 15.6 0.1 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF848 PF05852.11 OEU21419.1 - 0.0073 16.4 1.6 0.016 15.3 1.6 1.6 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) EF-hand_4 PF12763.7 OEU21419.1 - 0.031 14.2 0.1 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-MYND PF01753.18 OEU21420.1 - 9.9e-11 41.6 14.7 9.9e-11 41.6 14.7 6.0 2 2 2 4 4 4 1 MYND finger Pkinase PF00069.25 OEU21422.1 - 2.1e-25 89.6 0.2 3.1e-25 89.0 0.2 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21422.1 - 7.1e-19 68.1 0.1 3.5e-09 36.3 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OEU21422.1 - 0.0001 21.5 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OEU21422.1 - 0.0033 17.4 0.3 0.0041 17.1 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU21422.1 - 0.0063 15.9 0.0 0.0071 15.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OEU21422.1 - 0.02 14.3 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OEU21422.1 - 0.021 14.4 0.9 0.47 10.0 0.1 2.0 1 1 1 2 2 2 0 RIO1 family YukC PF10140.9 OEU21422.1 - 0.046 12.6 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PT PF04886.12 OEU21423.1 - 3.1e-05 23.4 79.0 0.026 14.0 19.8 5.2 3 1 0 3 3 3 3 PT repeat PCI PF01399.27 OEU21424.1 - 4.4e-19 68.9 1.0 9.4e-18 64.7 0.9 2.4 2 0 0 2 2 2 1 PCI domain RPN6_N PF18055.1 OEU21424.1 - 0.0025 18.1 0.8 0.0025 18.1 0.8 2.5 4 0 0 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain DDRGK PF09756.9 OEU21424.1 - 0.0044 16.6 0.8 0.0088 15.7 0.8 1.5 1 0 0 1 1 1 1 DDRGK domain RPN6_C_helix PF18503.1 OEU21424.1 - 0.017 14.8 0.1 0.046 13.5 0.1 1.8 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain AP1AR PF15745.5 OEU21424.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF1298 PF06974.13 OEU21424.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) TPR_21 PF09976.9 OEU21424.1 - 0.12 12.1 2.2 3.7 7.2 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain PrmA PF06325.13 OEU21425.1 - 2.4e-09 37.0 0.3 2.4e-09 37.0 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OEU21425.1 - 7.4e-05 23.4 0.0 0.00017 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OEU21425.1 - 0.00014 21.7 0.1 0.00027 20.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 OEU21425.1 - 0.00056 20.9 0.0 0.0013 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU21425.1 - 0.00061 20.4 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU21425.1 - 0.00079 19.2 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21425.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU21425.1 - 0.0017 17.9 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OEU21425.1 - 0.0046 16.9 0.1 0.0084 16.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 OEU21425.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OEU21425.1 - 0.048 13.4 0.3 0.083 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OEU21425.1 - 0.057 12.7 1.2 0.49 9.6 0.1 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase GST_N_2 PF13409.6 OEU21426.1 - 1.8e-15 57.0 0.0 3.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU21426.1 - 1.8e-13 50.3 0.2 3.3e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU21426.1 - 1.1e-08 35.2 0.3 2.1e-08 34.3 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU21426.1 - 0.00024 21.3 0.2 0.00048 20.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OEU21426.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OEU21426.1 - 0.14 12.6 0.0 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain E2F_TDP PF02319.20 OEU21427.1 - 4.9e-22 77.8 0.0 8.7e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OEU21427.1 - 5.6e-20 71.5 0.0 1.3e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain Agenet PF05641.12 OEU21428.1 - 0.013 16.0 0.1 0.013 16.0 0.1 2.1 2 0 0 2 2 2 0 Agenet domain BAH PF01426.18 OEU21428.1 - 0.089 12.6 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 BAH domain Colicin-DNase PF12639.7 OEU21428.1 - 1.9 9.4 7.7 1.6 9.6 0.3 2.5 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin TIM PF00121.18 OEU21429.1 - 8.7e-74 247.9 0.0 1.1e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PGI PF00342.19 OEU21430.1 - 4.7e-242 803.8 0.1 5.4e-242 803.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FCD PF07729.12 OEU21430.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 FCD domain tRNA-synt_His PF13393.6 OEU21431.1 - 1.7e-46 159.0 0.0 2.3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OEU21431.1 - 1e-14 54.4 0.1 2.1e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OEU21431.1 - 2.1e-08 34.4 0.0 3e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 OEU21431.1 - 0.0074 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Zeta_toxin PF06414.12 OEU21432.1 - 1.7e-21 76.4 0.0 8.7e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 OEU21432.1 - 4.2e-08 33.5 0.0 3.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU21432.1 - 1e-05 26.0 1.6 0.00013 22.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain DAZAP2 PF11029.8 OEU21432.1 - 0.21 12.5 2.4 0.27 12.2 0.4 2.0 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) Cation_efflux PF01545.21 OEU21433.1 - 3.2e-28 98.8 3.7 4.5e-28 98.3 3.7 1.2 1 0 0 1 1 1 1 Cation efflux family Yippee-Mis18 PF03226.14 OEU21434.1 - 0.012 15.8 4.7 0.018 15.3 4.7 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_2 PF12756.7 OEU21434.1 - 0.11 12.9 0.5 0.11 12.9 0.5 2.1 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RibD_C PF01872.17 OEU21435.1 - 8.2e-27 94.3 0.0 5.7e-25 88.3 0.0 2.4 1 1 0 1 1 1 1 RibD C-terminal domain Pep1_7 PF17232.2 OEU21435.1 - 0.69 10.4 5.9 3.8 8.0 0.2 2.9 3 0 0 3 3 3 0 Elicitor peptide 1-7 DUF4807 PF16065.5 OEU21436.1 - 6.5e-05 22.6 2.1 0.00031 20.4 2.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4807) PAP_assoc PF03828.19 OEU21436.1 - 0.042 14.0 2.0 6.8 7.0 0.1 3.1 2 0 0 2 2 2 0 Cid1 family poly A polymerase 7tm_3 PF00003.22 OEU21437.1 - 5.2e-23 82.0 19.2 6.7e-23 81.6 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF5305 PF17231.2 OEU21437.1 - 0.018 14.5 0.2 0.056 12.8 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 OEU21437.1 - 0.34 11.2 2.0 0.62 10.4 0.2 2.2 2 0 0 2 2 2 0 Orf78 (ac78) SUR7 PF06687.12 OEU21437.1 - 1.6 8.3 16.1 0.09 12.4 3.9 2.7 2 1 1 3 3 3 0 SUR7/PalI family Lem_TRP PF08262.11 OEU21438.1 - 7.4 6.8 6.4 5.3 7.3 1.5 2.5 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide BolA PF01722.18 OEU21439.1 - 2.5e-17 62.9 0.0 3.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Exo70 PF03081.15 OEU21441.1 - 0.0036 16.4 0.1 0.011 14.8 0.1 1.8 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF1280 PF06918.14 OEU21441.1 - 0.004 16.8 0.1 0.7 9.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1280) CM1 PF03026.15 OEU21441.1 - 0.029 13.7 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 Influenza C virus M1 protein TetR_C_19 PF17924.1 OEU21441.1 - 2 9.0 7.6 21 5.7 2.6 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sporozoite_P67 PF05642.11 OEU21447.1 - 0.0088 14.2 0.9 0.0095 14.1 0.9 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen LrgB PF04172.16 OEU21447.1 - 0.068 12.7 1.3 0.19 11.2 0.5 1.8 2 0 0 2 2 2 0 LrgB-like family PLAC8 PF04749.17 OEU21448.1 - 0.0043 18.0 7.7 0.0071 17.3 7.7 1.5 1 1 0 1 1 1 1 PLAC8 family NAM-associated PF14303.6 OEU21450.1 - 2.5e-05 25.1 6.1 7e-05 23.6 5.9 1.9 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Amino_oxidase PF01593.24 OEU21451.1 - 3.2e-12 46.5 0.3 1.4e-11 44.4 0.3 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU21451.1 - 3.9e-11 43.0 0.2 8.4e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU21451.1 - 7.4e-09 35.6 0.5 7e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OEU21451.1 - 1.2e-07 31.2 1.3 1.9e-07 30.6 0.3 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OEU21451.1 - 1.4e-07 30.9 0.8 2.2e-06 27.1 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU21451.1 - 0.0003 20.1 3.8 0.0014 17.9 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU21451.1 - 0.0018 17.1 2.4 0.36 9.5 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OEU21451.1 - 0.0087 15.4 1.8 0.016 14.6 1.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 OEU21451.1 - 0.013 14.3 0.7 0.018 13.9 0.1 1.5 2 0 0 2 2 2 0 MCRA family Pyr_redox PF00070.27 OEU21451.1 - 0.028 15.0 1.3 0.2 12.2 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OEU21451.1 - 0.06 12.7 0.5 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.19 OEU21451.1 - 0.15 11.3 0.5 0.23 10.7 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OEU21451.1 - 0.43 9.6 5.4 1.3 8.0 2.7 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Ndc1_Nup PF09531.10 OEU21452.1 - 0.13 10.9 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PSI_PSAK PF01241.18 OEU21452.1 - 0.17 11.9 0.1 21 5.2 0.1 2.1 1 1 1 2 2 2 0 Photosystem I psaG / psaK zf-MYND PF01753.18 OEU21453.1 - 1.2e-08 34.9 12.9 1.2e-08 34.9 12.9 2.8 2 0 0 2 2 2 2 MYND finger SNF2_N PF00176.23 OEU21454.1 - 4.6e-34 117.7 0.0 7.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HTH_Tnp_Tc3_1 PF11427.8 OEU21454.1 - 0.066 13.1 0.1 0.64 9.9 0.1 2.4 2 0 0 2 2 2 0 Tc3 transposase zinc_ribbon_10 PF10058.9 OEU21454.1 - 0.86 9.4 3.1 8 6.3 0.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein SR-25 PF10500.9 OEU21454.1 - 1.9 8.0 10.1 5.6 6.5 10.1 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C3HC4_3 PF13920.6 OEU21455.1 - 1e-11 44.5 9.6 1.6e-11 43.9 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU21455.1 - 1.6e-05 24.7 12.8 2.8e-05 23.9 12.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OEU21455.1 - 0.0026 18.0 12.4 0.0026 18.0 12.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU21455.1 - 0.03 14.1 14.1 0.043 13.7 12.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU21455.1 - 0.12 12.3 11.6 0.22 11.5 11.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 OEU21455.1 - 2.1 8.7 11.8 1.1 9.5 9.7 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain Cyclin_N PF00134.23 OEU21456.1 - 3.1e-18 65.8 1.4 1.8e-15 56.8 0.3 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OEU21456.1 - 0.01 16.2 0.4 0.22 11.9 0.1 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 OEU21456.1 - 0.012 15.6 0.4 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat PRANC PF09372.10 OEU21456.1 - 0.057 13.7 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 PRANC domain Cyclin_C PF02984.19 OEU21456.1 - 0.063 13.4 2.7 0.15 12.1 0.1 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain TUDOR PF00567.24 OEU21456.1 - 0.094 12.8 0.4 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 Tudor domain Anophelin PF10731.9 OEU21457.1 - 0.23 11.3 0.6 0.61 10.0 0.6 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito IMUP PF15761.5 OEU21457.1 - 4 8.2 8.8 48 4.7 6.5 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Alpha_kinase PF02816.18 OEU21458.1 - 9e-33 113.9 0.6 4.3e-22 79.1 0.4 3.2 3 0 0 3 3 3 2 Alpha-kinase family VWA_2 PF13519.6 OEU21458.1 - 1.3e-05 25.8 0.1 7.7e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 OEU21458.1 - 0.00047 20.4 0.0 0.0035 17.6 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 OEU21458.1 - 0.00055 19.6 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT VWA domain DUF4258 PF14076.6 OEU21458.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) RXT2_N PF08595.11 OEU21458.1 - 0.081 12.9 3.7 0.074 13.1 1.7 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal PHB_acc_N PF07879.11 OEU21458.1 - 0.21 11.7 1.1 0.71 10.0 1.1 1.9 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain NOA36 PF06524.12 OEU21458.1 - 4.3 6.6 9.9 7 5.9 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein PPR_2 PF13041.6 OEU21459.1 - 6.9e-09 35.8 8.1 0.06 13.6 0.0 5.4 5 0 0 5 5 5 3 PPR repeat family PPR_1 PF12854.7 OEU21459.1 - 8.7e-08 31.7 5.7 0.011 15.4 0.4 4.6 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 OEU21459.1 - 9.3e-06 25.6 6.6 0.013 15.6 1.0 4.6 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 OEU21459.1 - 3.2e-05 23.9 3.6 2.4 8.6 0.0 4.2 3 0 0 3 3 3 3 PPR repeat Asparaginase PF00710.20 OEU21460.1 - 4.9e-18 65.4 0.0 7.3e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Peptidase_C1 PF00112.23 OEU21461.1 - 1.3e-30 107.1 8.5 1.3e-30 107.1 8.5 3.0 1 1 1 2 2 2 1 Papain family cysteine protease Mucin PF01456.17 OEU21461.1 - 1.1 9.3 19.0 2.3 8.2 7.0 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DEAD PF00270.29 OEU21462.1 - 7.5e-27 94.2 0.1 6.8e-26 91.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OEU21462.1 - 1.6e-13 51.2 0.6 6e-13 49.4 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OEU21462.1 - 9.1e-12 45.3 0.0 2.5e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OEU21462.1 - 2.9e-08 33.9 1.2 1.2e-07 31.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Crust_neurohorm PF01147.17 OEU21462.1 - 0.09 12.6 0.4 0.21 11.4 0.4 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Urm1 PF09138.11 OEU21463.1 - 0.12 12.7 1.2 0.21 12.0 0.0 2.0 3 0 0 3 3 3 0 Urm1 (Ubiquitin related modifier) Ad_Cy_reg PF16701.5 OEU21465.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain NTP_transferase PF00483.23 OEU21466.1 - 0.0019 17.8 0.1 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase AAA_33 PF13671.6 OEU21466.1 - 0.03 14.5 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Chloroa_b-bind PF00504.21 OEU21467.1 - 5.2e-29 101.9 0.1 8e-29 101.2 0.1 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Peptidase_A22B PF04258.13 OEU21469.1 - 2.3e-47 161.9 0.2 3e-47 161.5 0.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OEU21469.1 - 0.0034 16.9 3.1 0.034 13.6 3.0 2.3 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease MCM6_C PF18263.1 OEU21470.1 - 0.0016 18.7 4.7 0.0056 16.9 4.7 2.0 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Receptor_IA-2 PF11548.8 OEU21470.1 - 1.2 9.1 5.8 0.62 10.1 2.3 2.3 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 MatP_C PF17414.2 OEU21470.1 - 7.4 6.8 9.2 0.7 10.1 0.4 3.5 4 0 0 4 4 4 0 MatP C-terminal ribbon-helix-helix domain DNA_methylase PF00145.17 OEU21471.1 - 7.4e-17 61.7 0.9 5.4e-16 58.8 0.9 2.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase REV PF00424.18 OEU21471.1 - 0.11 12.5 2.3 0.21 11.6 2.3 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Peptidase_A21 PF03566.13 OEU21471.1 - 0.13 10.5 1.0 0.2 9.9 1.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 SPT6_acidic PF14632.6 OEU21471.1 - 0.2 12.2 1.0 0.46 11.1 1.0 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 GST_N PF02798.20 OEU21473.1 - 1.1e-12 48.0 0.0 2.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU21473.1 - 1.6e-12 47.6 0.0 2.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU21473.1 - 3.7e-11 43.1 0.0 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU21473.1 - 3.5e-05 23.7 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU21473.1 - 0.00029 21.0 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU21473.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NigD_N PF12667.7 OEU21474.1 - 0.00015 21.8 0.5 0.66 10.1 0.1 2.4 2 0 0 2 2 2 2 NigD-like N-terminal OB domain SH3_3 PF08239.11 OEU21474.1 - 0.011 16.0 0.4 0.94 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain S1_2 PF13509.6 OEU21474.1 - 0.085 12.9 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 S1 domain OAD_gamma PF04277.13 OEU21475.1 - 0.0023 18.5 0.0 0.0085 16.7 0.0 1.9 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF4578 PF15147.6 OEU21475.1 - 1.9 9.4 10.0 0.37 11.7 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) DivIC PF04977.15 OEU21475.1 - 2.6 7.9 7.5 6.7 6.6 7.5 1.7 1 0 0 1 1 1 0 Septum formation initiator SR-25 PF10500.9 OEU21476.1 - 0.052 13.1 9.4 0.077 12.6 9.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 OEU21476.1 - 2.5 7.7 7.0 3.6 7.3 7.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GDPD PF03009.17 OEU21477.1 - 9.6e-12 45.2 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.19 OEU21477.1 - 0.081 12.8 7.5 4.4 7.1 0.1 2.4 1 1 1 2 2 2 0 SPX domain BTB PF00651.31 OEU21479.1 - 1.2e-10 41.6 0.1 9.8e-10 38.6 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain DivIC PF04977.15 OEU21479.1 - 0.01 15.6 4.6 0.01 15.6 4.6 2.5 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 OEU21479.1 - 0.01 14.9 2.4 0.015 14.4 2.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 OEU21479.1 - 0.023 14.0 10.3 0.038 13.3 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4618 PF15397.6 OEU21479.1 - 0.023 14.1 5.4 0.046 13.1 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.21 OEU21479.1 - 0.023 14.8 2.4 0.023 14.8 2.4 2.4 2 1 1 3 3 3 0 bZIP transcription factor SLX9 PF15341.6 OEU21479.1 - 0.054 13.9 4.7 0.11 12.8 4.7 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF724 PF05266.14 OEU21479.1 - 0.097 12.5 4.7 0.15 11.8 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BMFP PF04380.13 OEU21479.1 - 0.15 12.6 2.4 0.38 11.3 2.3 1.8 1 1 0 1 1 1 0 Membrane fusogenic activity Cnn_1N PF07989.11 OEU21479.1 - 0.45 10.7 8.4 0.11 12.6 2.7 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Tup_N PF08581.10 OEU21479.1 - 0.95 9.8 6.2 2.1 8.7 6.2 1.6 1 0 0 1 1 1 0 Tup N-terminal bZIP_Maf PF03131.17 OEU21479.1 - 3.2 8.3 8.8 0.87 10.2 4.8 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OEU21479.1 - 6.1 7.0 8.7 4.5 7.4 2.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper zf-RVT PF13966.6 OEU21480.1 - 0.063 14.0 0.9 0.063 14.0 0.9 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase zf-MYND PF01753.18 OEU21482.1 - 8.5e-09 35.4 11.6 8.5e-09 35.4 11.6 2.5 2 1 0 2 2 1 1 MYND finger zf-C3HC4_3 PF13920.6 OEU21482.1 - 4.3e-08 32.9 7.5 4.3e-08 32.9 7.5 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 OEU21482.1 - 6.5e-08 32.1 2.0 0.11 12.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-C3HC4 PF00097.25 OEU21482.1 - 1.2e-07 31.4 7.0 1.2e-07 31.4 7.0 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU21482.1 - 1.4e-07 31.4 8.1 3.5e-07 30.1 8.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU21482.1 - 9.8e-07 29.0 11.4 9.8e-07 29.0 11.4 2.3 2 0 0 2 2 1 1 Ring finger domain TPR_16 PF13432.6 OEU21482.1 - 4.1e-06 27.3 0.1 0.041 14.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU21482.1 - 8.8e-06 25.9 1.1 0.17 12.1 0.0 3.4 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4_2 PF13923.6 OEU21482.1 - 1.6e-05 24.6 8.8 1.6e-05 24.6 8.8 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU21482.1 - 1.6e-05 25.0 7.9 1.6e-05 25.0 7.9 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING TPR_19 PF14559.6 OEU21482.1 - 9.1e-05 22.9 3.7 2.7 8.6 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 OEU21482.1 - 0.00031 20.6 9.5 0.00031 20.6 9.5 2.5 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU21482.1 - 0.00039 20.2 5.7 0.00039 20.2 5.7 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OEU21482.1 - 0.0027 18.0 7.5 0.0027 18.0 7.5 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain TPR_1 PF00515.28 OEU21482.1 - 0.0044 16.8 0.8 2.4 8.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OEU21482.1 - 0.0048 16.9 1.5 0.052 13.6 0.4 2.7 1 1 0 2 2 2 1 Putative TPR-like repeat TPR_12 PF13424.6 OEU21482.1 - 0.006 16.9 6.8 0.77 10.1 0.9 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21482.1 - 0.021 15.6 1.8 1.8 9.6 0.1 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 OEU21482.1 - 0.089 12.5 4.6 0.3 10.9 4.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger TPR_6 PF13174.6 OEU21482.1 - 0.16 12.7 6.3 6.4 7.6 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 OEU21482.1 - 1.6 8.8 9.2 0.039 14.0 2.4 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_8 PF13181.6 OEU21482.1 - 2.3 8.6 8.2 20 5.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat HA PF03457.14 OEU21483.1 - 2.7e-55 184.6 0.5 1e-19 70.6 0.0 3.0 3 0 0 3 3 3 3 Helicase associated domain Ank_4 PF13637.6 OEU21484.1 - 0.048 14.2 2.1 9.3 7.0 0.0 4.3 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Cys_Met_Meta_PP PF01053.20 OEU21485.1 - 8.5e-103 343.8 0.0 1.1e-101 340.1 0.0 2.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OEU21485.1 - 0.0034 16.6 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OEU21485.1 - 0.18 10.7 0.0 0.45 9.4 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class-V Ubie_methyltran PF01209.18 OEU21486.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_S28 PF05577.12 OEU21487.1 - 9.3e-47 159.8 0.3 4.1e-37 128.0 0.0 3.5 3 0 0 3 3 3 3 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 OEU21487.1 - 5e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU21487.1 - 8e-05 22.4 0.0 0.00021 21.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OEU21487.1 - 0.0006 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OEU21487.1 - 0.0037 16.8 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OEU21487.1 - 0.043 14.4 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cyclin_N PF00134.23 OEU21488.1 - 5.9e-16 58.4 2.1 7e-16 58.1 2.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_N PF00134.23 OEU21489.1 - 6.3e-15 55.0 0.3 1.7e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU21489.1 - 4.2e-10 39.8 1.7 1e-09 38.5 0.2 2.4 2 1 1 3 3 3 1 Cyclin, C-terminal domain MinE PF03776.14 OEU21489.1 - 0.031 14.3 0.0 0.49 10.4 0.0 2.6 3 0 0 3 3 3 0 Septum formation topological specificity factor MinE SNARE_assoc PF09335.11 OEU21490.1 - 1.9e-08 34.8 4.6 4.6e-08 33.6 0.2 2.6 2 1 0 2 2 2 1 SNARE associated Golgi protein ETRAMP PF09716.10 OEU21490.1 - 0.01 15.9 0.0 0.036 14.1 0.0 2.1 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Peptidase_S49_N PF08496.10 OEU21490.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Vma12 PF11712.8 OEU21491.1 - 9e-07 29.0 0.1 2.9e-06 27.4 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3899 PF13038.6 OEU21491.1 - 0.46 11.0 11.5 1.2 9.7 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3899) EphA2_TM PF14575.6 OEU21491.1 - 1.1 10.2 2.9 3.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 OEU21491.1 - 3.6 7.8 0.0 3.6 7.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) DNA_pol_E_B PF04042.16 OEU21492.1 - 1.6e-20 73.4 1.1 2.9e-20 72.5 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Lipl32 PF12103.8 OEU21492.1 - 0.25 11.0 2.1 0.35 10.5 1.1 1.8 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order CCB2_CCB4 PF11152.8 OEU21493.1 - 2.2e-31 108.7 0.7 2.7e-31 108.4 0.7 1.2 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Hydrolase_3 PF08282.12 OEU21494.1 - 0.01 15.6 3.8 0.019 14.7 3.8 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_C8 PF03569.13 OEU21494.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C8 zf-MYND PF01753.18 OEU21495.1 - 0.0017 18.4 12.8 0.0017 18.4 12.8 2.3 1 1 1 2 2 2 2 MYND finger EAP30 PF04157.16 OEU21496.1 - 4.1e-54 183.4 0.0 4.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family RPA_C PF08784.11 OEU21496.1 - 0.027 15.1 0.4 2.5 8.8 0.0 2.5 2 1 0 2 2 2 0 Replication protein A C terminal MFS_2 PF13347.6 OEU21497.1 - 2.2e-20 72.7 16.7 9.6e-09 34.3 1.4 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 OEU21497.1 - 0.00047 19.1 0.4 0.16 10.8 0.0 3.0 2 1 1 3 3 3 2 MFS_1 like family Ost5 PF05251.12 OEU21497.1 - 0.054 13.8 7.5 0.24 11.7 2.9 3.0 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF5305 PF17231.2 OEU21497.1 - 0.067 12.6 2.2 0.11 11.9 0.4 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5305) DHHC PF01529.20 OEU21497.1 - 0.37 10.9 2.4 5.9 7.0 0.1 2.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase EamA PF00892.20 OEU21497.1 - 4.7 7.4 16.5 0.083 13.1 5.0 3.2 3 0 0 3 3 3 0 EamA-like transporter family HA PF03457.14 OEU21498.1 - 1.2e-51 172.8 5.3 1.7e-16 60.3 0.1 3.1 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU21498.1 - 0.00099 19.2 0.7 7.5 6.7 0.1 3.3 3 0 0 3 3 3 2 Transcriptional regulation of mitochondrial recombination DUF3822 PF12864.7 OEU21498.1 - 0.0018 17.5 5.6 0.088 12.0 0.8 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3822) DUF5522 PF17653.1 OEU21498.1 - 0.055 13.4 0.9 11 6.1 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5522) PHINT_rpt PF14882.6 OEU21498.1 - 1.8 8.9 8.9 1.1e+02 3.2 0.0 5.1 5 0 0 5 5 5 0 Phage-integrase repeat unit Myb_DNA-binding PF00249.31 OEU21499.1 - 7.9e-14 51.6 4.9 4.3e-06 26.8 2.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU21499.1 - 1.4e-10 41.3 5.1 5.4e-06 26.6 1.8 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU21499.1 - 0.032 14.1 0.1 0.11 12.4 0.0 1.8 2 1 0 2 2 2 0 Myb DNA-binding like DUF2774 PF11242.8 OEU21499.1 - 0.077 13.2 0.1 11 6.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2774) Acetyltransf_1 PF00583.25 OEU21500.1 - 0.00021 21.5 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU21500.1 - 0.0025 18.2 0.0 0.0074 16.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SUIM_assoc PF16619.5 OEU21500.1 - 0.045 13.8 16.4 3.5 7.8 0.7 4.8 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF2236 PF09995.9 OEU21501.1 - 0.012 15.8 0.2 0.017 15.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) VWA PF00092.28 OEU21502.1 - 3.6e-09 37.1 0.1 1.1e-08 35.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OEU21502.1 - 1.6e-05 25.5 0.0 6.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OEU21502.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain Helicase_C PF00271.31 OEU21503.1 - 2.2e-07 31.2 0.9 9.9e-07 29.1 0.9 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 OEU21503.1 - 0.11 12.7 0.4 0.17 12.0 0.4 1.4 1 1 0 1 1 1 0 Helicase C-terminal domain VWA PF00092.28 OEU21504.1 - 6.2e-09 36.3 0.0 1.3e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OEU21504.1 - 0.00097 19.8 0.0 0.0093 16.6 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OEU21504.1 - 0.0017 18.3 0.0 0.0038 17.2 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain OB_aCoA_assoc PF01796.17 OEU21504.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated rve PF00665.26 OEU21505.1 - 0.00021 21.4 0.0 0.00094 19.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 OEU21505.1 - 0.0028 17.3 0.5 0.013 15.1 0.1 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type R3H-assoc PF13902.6 OEU21505.1 - 0.0086 16.5 0.1 0.025 14.9 0.1 1.8 1 0 0 1 1 1 1 R3H-associated N-terminal domain IFT20 PF14931.6 OEU21505.1 - 0.046 13.9 0.9 0.19 11.9 0.9 2.0 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 TPR_1 PF00515.28 OEU21506.1 - 5.8e-30 101.9 22.8 0.00015 21.4 0.0 13.3 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21506.1 - 1.9e-28 96.3 30.8 0.0014 18.6 0.0 15.4 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21506.1 - 1.2e-18 67.4 19.8 0.008 16.7 2.4 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21506.1 - 1.5e-16 59.7 26.5 0.0087 16.8 0.2 13.8 10 5 5 15 15 15 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU21506.1 - 1.1e-12 48.0 19.6 0.08 13.2 0.5 7.7 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OEU21506.1 - 5.9e-12 44.8 20.2 1 9.7 0.1 11.9 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 OEU21506.1 - 3.7e-11 43.2 21.0 0.0013 19.0 0.2 9.4 10 1 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 OEU21506.1 - 5.1e-08 32.9 5.8 1.2 9.3 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 OEU21506.1 - 4e-07 29.9 3.2 8.4e-07 28.9 1.2 2.5 1 1 1 2 2 2 1 RING-type zinc-finger TPR_7 PF13176.6 OEU21506.1 - 1.5e-06 27.8 7.9 9.1 6.6 0.0 8.3 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21506.1 - 2.1e-05 25.1 25.3 2.5 8.8 0.0 9.5 8 2 0 9 9 8 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 OEU21506.1 - 8.3e-05 22.3 8.8 9e-05 22.2 2.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BTAD PF03704.17 OEU21506.1 - 0.00012 22.5 19.3 0.72 10.3 0.0 7.8 7 1 0 7 7 7 1 Bacterial transcriptional activator domain zf-RING_2 PF13639.6 OEU21506.1 - 0.00015 22.0 10.8 0.00053 20.3 10.8 2.0 1 1 0 1 1 1 1 Ring finger domain MIT PF04212.18 OEU21506.1 - 0.00026 21.0 20.9 3.9 7.6 0.3 10.0 11 1 1 12 12 10 1 MIT (microtubule interacting and transport) domain zf-C3HC4 PF00097.25 OEU21506.1 - 0.00057 19.7 14.1 0.001 18.9 12.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) YfdX PF10938.8 OEU21506.1 - 0.00061 19.7 14.9 0.9 9.5 0.1 7.1 7 0 0 7 7 7 1 YfdX protein PPDK_N PF01326.19 OEU21506.1 - 0.00072 18.9 1.2 0.15 11.3 0.1 3.4 3 0 0 3 3 3 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Fis1_TPR_C PF14853.6 OEU21506.1 - 0.002 18.2 2.3 0.63 10.2 0.1 3.8 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat zf-RING_5 PF14634.6 OEU21506.1 - 0.0031 17.4 12.4 0.0074 16.2 12.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU21506.1 - 0.0041 16.9 12.5 0.017 15.0 12.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 OEU21506.1 - 0.0047 16.6 20.6 44 3.9 0.0 10.3 11 2 1 12 12 9 0 TPR repeat zf-C3HC4_4 PF15227.6 OEU21506.1 - 0.012 15.7 10.0 0.12 12.5 10.3 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PUL PF08324.11 OEU21506.1 - 0.018 14.3 0.1 1.2 8.3 0.0 3.3 3 0 0 3 3 3 0 PUL domain TPR_17 PF13431.6 OEU21506.1 - 0.077 13.4 20.2 12 6.6 0.0 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.14 OEU21506.1 - 0.088 12.7 0.8 0.65 9.9 0.8 2.6 1 0 0 1 1 1 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 OEU21506.1 - 0.1 12.5 13.5 1.2 9.1 13.5 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_3 PF07720.12 OEU21506.1 - 0.12 12.4 4.9 34 4.6 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21506.1 - 0.12 13.0 11.5 2.1e+02 2.9 0.0 8.2 9 0 0 9 9 6 0 Tetratricopeptide repeat Baculo_RING PF05883.11 OEU21506.1 - 0.14 12.1 0.6 0.55 10.2 0.6 2.0 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Alkyl_sulf_dimr PF14863.6 OEU21506.1 - 0.28 11.6 14.5 36 4.8 0.6 7.1 5 4 3 8 8 7 0 Alkyl sulfatase dimerisation NRBF2_MIT PF17169.4 OEU21506.1 - 0.31 11.3 7.6 11 6.4 0.2 5.1 5 0 0 5 5 4 0 MIT domain of nuclear receptor-binding factor 2 USP8_dimer PF08969.11 OEU21506.1 - 0.32 11.2 3.7 10 6.3 0.0 4.1 4 0 0 4 4 3 0 USP8 dimerisation domain zf-Nse PF11789.8 OEU21506.1 - 0.45 10.4 4.3 1 9.2 4.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 OEU21506.1 - 7.5 5.8 12.7 0.11 11.9 3.6 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Pox_Ag35 PF03286.14 OEU21507.1 - 0.17 11.7 19.0 1.1 9.0 7.1 3.0 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Ank_2 PF12796.7 OEU21508.1 - 0.062 13.9 0.0 3.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) PI_PP_C PF18365.1 OEU21508.1 - 0.35 10.9 2.0 4.5 7.3 0.4 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Glutaredoxin PF00462.24 OEU21509.1 - 3e-11 43.3 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 OEU21509.1 - 0.15 12.4 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Exo_endo_phos PF03372.23 OEU21511.1 - 6.6e-12 45.4 0.0 2.7e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7TM_GPCR_Srh PF10318.9 OEU21511.1 - 0.048 12.7 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh HA PF03457.14 OEU21512.1 - 9.1e-35 118.8 0.0 3.6e-16 59.2 0.0 2.0 2 0 0 2 2 2 2 Helicase associated domain FemAB PF02388.16 OEU21512.1 - 0.037 12.9 0.1 0.043 12.7 0.1 1.1 1 0 0 1 1 1 0 FemAB family RsgA_GTPase PF03193.16 OEU21514.1 - 5.4e-33 114.3 0.5 2.3e-29 102.4 0.5 2.9 2 1 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 OEU21514.1 - 2.9e-08 34.3 1.6 4.9e-08 33.6 0.1 2.1 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 OEU21514.1 - 1.6e-07 31.4 0.2 8.4e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 OEU21514.1 - 0.0017 17.7 0.5 0.0032 16.8 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_25 PF13481.6 OEU21514.1 - 0.003 17.1 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OEU21514.1 - 0.0084 16.5 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Dynamin_N PF00350.23 OEU21514.1 - 0.0094 16.0 0.2 0.0094 16.0 0.2 4.1 3 2 1 4 4 4 1 Dynamin family AAA_16 PF13191.6 OEU21514.1 - 0.016 15.6 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OEU21514.1 - 0.017 15.3 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OEU21514.1 - 0.025 14.3 0.0 0.076 12.7 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein FeoB_N PF02421.18 OEU21514.1 - 0.043 13.4 0.6 0.23 10.9 0.1 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_7 PF12775.7 OEU21514.1 - 0.055 13.0 0.2 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DNA_pol_phi PF04931.13 OEU21514.1 - 0.077 11.1 4.2 0.13 10.4 4.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi AAA_29 PF13555.6 OEU21514.1 - 0.079 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 OEU21514.1 - 0.079 12.5 2.6 1.3 8.5 0.4 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RRN3 PF05327.11 OEU21514.1 - 0.17 10.4 1.5 0.31 9.5 1.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 OEU21514.1 - 2.6 6.2 9.7 0.11 10.7 2.8 1.9 2 0 0 2 2 2 0 CDC45-like protein Arm PF00514.23 OEU21515.1 - 0.96 9.6 5.3 19 5.5 0.0 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat zf-A20 PF01754.16 OEU21516.1 - 1.9e-10 40.5 8.1 2.9e-10 39.9 8.1 1.3 1 0 0 1 1 1 1 A20-like zinc finger Peptidase_S46 PF10459.9 OEU21516.1 - 0.0043 15.8 2.6 0.0049 15.6 2.6 1.1 1 0 0 1 1 1 1 Peptidase S46 Ndc1_Nup PF09531.10 OEU21516.1 - 0.54 8.9 10.2 0.69 8.5 10.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 OEU21516.1 - 1.2 9.7 6.8 1.6 9.3 6.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.13 OEU21516.1 - 2.1 8.2 12.6 2.8 7.8 12.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GST_N_3 PF13417.6 OEU21517.1 - 1.3e-13 51.1 0.0 5e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU21517.1 - 9.7e-12 45.0 0.0 3.1e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OEU21517.1 - 1.3e-05 25.5 0.1 6.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU21517.1 - 0.00087 19.3 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OEU21517.1 - 0.002 18.3 0.3 0.0074 16.5 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin CDP-OH_P_transf PF01066.21 OEU21518.1 - 2.6e-13 50.5 0.0 2.6e-13 50.5 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1289 PF06945.13 OEU21519.1 - 3.9e-09 36.2 2.5 6.7e-09 35.4 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) HCO3_cotransp PF00955.21 OEU21521.1 - 2e-126 422.8 21.6 7.4e-76 256.0 5.2 2.9 1 1 1 2 2 2 2 HCO3- transporter family SAYSvFN PF10260.9 OEU21522.1 - 0.07 13.1 0.6 0.79 9.7 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) EGF PF00008.27 OEU21522.1 - 0.15 12.4 9.2 0.46 10.8 4.9 2.8 2 0 0 2 2 2 0 EGF-like domain HA PF03457.14 OEU21523.1 - 5.4e-34 116.3 2.2 1.6e-17 63.6 0.1 2.4 3 0 0 3 3 3 2 Helicase associated domain DUF4167 PF13763.6 OEU21523.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Gag_p10 PF02337.17 OEU21523.1 - 0.15 12.0 1.0 1.4 8.9 0.6 2.5 2 1 1 3 3 3 0 Retroviral GAG p10 protein SpoU_methylase PF00588.19 OEU21524.1 - 1.1e-05 25.6 0.0 0.003 17.7 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF3287 PF11690.8 OEU21524.1 - 0.051 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF812 PF05667.11 OEU21525.1 - 0.12 11.2 3.4 0.17 10.7 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 OEU21525.1 - 0.18 12.0 2.6 0.3 11.3 2.6 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EGF_2 PF07974.13 OEU21526.1 - 0.0018 18.6 12.2 0.0023 18.3 11.7 1.5 1 1 0 1 1 1 1 EGF-like domain EGF PF00008.27 OEU21526.1 - 0.022 15.0 6.5 0.022 15.0 6.5 1.8 1 1 1 2 2 2 0 EGF-like domain hEGF PF12661.7 OEU21526.1 - 7.1 7.4 15.0 0.43 11.3 9.4 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF Fasciclin PF02469.22 OEU21527.1 - 3.6e-32 111.3 0.1 4e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Fasciclin domain SBP_bac_3 PF00497.20 OEU21528.1 - 1.3e-08 34.6 0.1 0.00047 19.6 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 OEU21528.1 - 0.00039 20.6 0.0 0.00093 19.4 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site HATPase_c PF02518.26 OEU21529.1 - 5e-26 91.4 0.7 1.1e-25 90.3 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OEU21529.1 - 8e-25 87.2 2.4 2e-24 85.9 2.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OEU21529.1 - 5.4e-13 48.8 0.1 3.8e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OEU21529.1 - 2.6e-06 27.3 0.9 5.6e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CofC PF01983.16 OEU21529.1 - 0.028 13.6 4.9 0.097 11.8 0.6 2.2 2 0 0 2 2 2 0 Guanylyl transferase CofC like Enolase_N PF03952.16 OEU21529.1 - 0.039 14.1 1.2 6 7.1 0.0 3.3 2 1 0 3 3 3 0 Enolase, N-terminal domain D123 PF07065.14 OEU21530.1 - 2.9e-64 217.1 0.5 2.9e-64 217.1 0.5 2.7 2 1 0 2 2 2 1 D123 R2K_2 PF18299.1 OEU21530.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Reg_prop PF07494.11 OEU21530.1 - 0.072 13.3 0.1 0.35 11.2 0.1 2.3 1 0 0 1 1 1 0 Two component regulator propeller DNA_primase_lrg PF04104.14 OEU21531.1 - 2.6e-10 40.1 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Herpes_UL52 PF03121.15 OEU21531.1 - 0.045 13.7 1.5 0.082 12.9 1.5 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase ABC2_membrane_5 PF13346.6 OEU21532.1 - 0.019 14.5 0.3 0.038 13.5 0.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Cytomega_TRL10 PF06084.11 OEU21532.1 - 0.079 13.0 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Ac76 PF05814.11 OEU21532.1 - 0.089 12.8 0.1 0.32 11.0 0.1 1.9 1 0 0 1 1 1 0 Orf76 (Ac76) Gly_transf_sug PF04488.15 OEU21533.1 - 3.5e-13 50.0 0.1 1.4e-12 48.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OEU21533.1 - 7.4e-06 25.5 0.0 9.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 OEU21533.1 - 0.0004 19.8 0.0 0.0021 17.4 0.0 2.0 3 0 0 3 3 3 1 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.12 OEU21533.1 - 0.0069 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Glyco_tranf_2_4 PF13704.6 OEU21534.1 - 0.0006 20.3 4.2 0.0026 18.2 2.4 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 2 LRR_8 PF13855.6 OEU21535.1 - 0.0022 17.7 5.2 8.3 6.3 0.1 4.7 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OEU21535.1 - 0.27 11.7 13.8 9.1 6.9 0.4 4.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU21535.1 - 0.5 11.1 3.3 33 5.6 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat FMN_dh PF01070.18 OEU21536.1 - 7e-120 400.2 0.0 8.7e-120 399.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OEU21536.1 - 2.6e-06 26.7 2.2 5.5e-06 25.6 1.4 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OEU21536.1 - 1.6e-05 24.3 0.3 2.5e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OEU21536.1 - 0.0018 17.7 0.5 0.0018 17.7 0.5 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 OEU21536.1 - 0.0052 16.1 0.4 0.22 10.8 0.8 2.2 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 OEU21536.1 - 0.014 14.6 0.2 0.024 13.9 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 OEU21536.1 - 0.059 12.8 0.1 0.28 10.6 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 OEU21536.1 - 0.18 11.2 0.1 0.45 9.9 0.0 1.6 1 1 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator zf-CHC2 PF01807.20 OEU21537.1 - 0.039 13.7 0.2 0.071 12.9 0.2 1.4 1 1 0 1 1 1 0 CHC2 zinc finger DAO PF01266.24 OEU21538.1 - 2.9e-27 96.2 0.0 3.1e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pho88 PF10032.9 OEU21539.1 - 5.8e-27 94.1 0.2 8.9e-27 93.5 0.2 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 OEU21539.1 - 1.3e-11 44.9 0.0 1.8e-06 28.5 0.0 3.0 2 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU21539.1 - 6.6e-05 23.1 0.0 0.002 18.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU21539.1 - 0.00011 22.6 0.0 0.045 14.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU21539.1 - 0.0015 18.9 0.3 1.3 9.6 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 OEU21539.1 - 0.026 15.1 0.0 11 7.0 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ysc84 PF04366.12 OEU21540.1 - 5.3e-06 26.2 0.3 8.1e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Aminotran_1_2 PF00155.21 OEU21541.1 - 9.1e-43 146.8 0.0 1.2e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OEU21541.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 OEU21541.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Ysc84 PF04366.12 OEU21544.1 - 5.7e-05 22.9 0.1 0.00011 22.0 0.0 1.5 1 1 1 2 2 2 1 Las17-binding protein actin regulator Endotoxin_M PF00555.19 OEU21544.1 - 0.048 13.7 1.2 0.061 13.4 0.3 1.6 1 1 1 2 2 2 0 delta endotoxin SGL PF08450.12 OEU21545.1 - 1.5e-18 67.3 0.1 4.2e-18 65.8 0.1 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Fasciclin PF02469.22 OEU21545.1 - 5.7e-05 23.3 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Fasciclin domain Arylesterase PF01731.20 OEU21545.1 - 0.00012 22.2 0.0 0.00032 20.8 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 OEU21545.1 - 0.0015 18.6 0.0 0.017 15.2 0.0 2.6 3 0 0 3 3 3 1 Strictosidine synthase Reg_prop PF07494.11 OEU21545.1 - 0.043 14.0 0.2 14 6.4 0.0 3.4 2 0 0 2 2 2 0 Two component regulator propeller NHL PF01436.21 OEU21545.1 - 2.3 8.4 4.4 5.5 7.2 0.0 3.9 5 0 0 5 5 5 0 NHL repeat ubiquitin PF00240.23 OEU21547.1 - 4.1e-11 42.5 0.0 7.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 OEU21547.1 - 0.019 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Jagunal PF07086.12 OEU21547.1 - 0.12 12.4 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis Cu-oxidase_2 PF07731.14 OEU21548.1 - 1.6e-36 125.1 0.2 2.8e-36 124.3 0.2 1.4 1 0 0 1 1 1 1 Multicopper oxidase Dirigent PF03018.14 OEU21548.1 - 0.04 13.7 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Dirigent-like protein PT PF04886.12 OEU21550.1 - 7 6.3 6.8 1.5 8.4 2.2 2.2 2 0 0 2 2 2 0 PT repeat ADH_zinc_N PF00107.26 OEU21551.1 - 6.7e-14 52.0 0.4 3.6e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU21551.1 - 1.6e-13 51.8 0.1 3.6e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU21551.1 - 2.4e-08 33.8 0.1 2e-07 30.8 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OEU21551.1 - 0.00019 21.0 0.1 0.00038 20.0 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus zf-RING_2 PF13639.6 OEU21552.1 - 8.6e-12 45.2 5.9 1.9e-11 44.1 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU21552.1 - 1.3e-10 40.8 1.6 2.5e-10 39.9 1.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU21552.1 - 4.4e-06 26.5 3.4 1.1e-05 25.2 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU21552.1 - 5.5e-06 26.1 4.3 1.6e-05 24.6 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU21552.1 - 7.6e-05 22.9 5.2 0.00027 21.2 5.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OEU21552.1 - 0.0015 18.4 4.7 0.004 17.1 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 OEU21552.1 - 0.01 16.0 2.8 0.026 14.7 2.8 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OEU21552.1 - 0.011 15.7 5.7 0.029 14.4 5.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OEU21552.1 - 0.017 15.0 3.0 0.033 14.0 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OEU21552.1 - 0.032 14.3 4.3 0.13 12.4 4.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OEU21552.1 - 0.12 12.1 4.2 0.28 10.8 4.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OEU21552.1 - 0.78 10.0 4.8 1.9 8.7 4.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OEU21552.1 - 2.7 7.9 7.9 1.4 8.9 5.3 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 HA PF03457.14 OEU21553.1 - 2.6e-51 171.8 5.4 5.6e-17 61.8 0.2 3.0 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU21553.1 - 0.0014 18.7 1.0 2.2 8.4 0.1 3.3 3 0 0 3 3 3 2 Transcriptional regulation of mitochondrial recombination HA PF03457.14 OEU21554.1 - 1.2e-38 131.3 1.1 1.1e-18 67.3 0.1 2.0 2 0 0 2 2 2 2 Helicase associated domain Mhr1 PF12829.7 OEU21554.1 - 0.0042 17.1 0.2 4.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulation of mitochondrial recombination mRNA_cap_C PF03919.15 OEU21554.1 - 0.0054 17.4 1.2 0.11 13.1 0.1 2.1 1 1 1 2 2 2 1 mRNA capping enzyme, C-terminal domain DUF1803 PF08820.10 OEU21554.1 - 0.095 12.7 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) ANAPC4_WD40 PF12894.7 OEU21555.1 - 3.2e-13 49.8 0.4 8.2e-05 22.8 0.1 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OEU21555.1 - 1.5e-07 32.0 13.4 2.9e-05 24.7 0.2 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.6 OEU21555.1 - 0.013 15.1 0.0 1.5 8.4 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain HDC PF02329.16 OEU21556.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Histidine carboxylase PI chain RVT_1 PF00078.27 OEU21557.1 - 5e-06 26.2 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OEU21557.1 - 0.0039 17.0 0.1 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase SOAR PF16533.5 OEU21557.1 - 0.014 15.3 1.5 1 9.4 0.3 3.4 2 0 0 2 2 2 0 STIM1 Orai1-activating region Rxt3 PF08642.10 OEU21557.1 - 0.59 10.9 0.0 0.59 10.9 0.0 2.9 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 PIP5K PF01504.18 OEU21559.1 - 2.5e-67 227.0 0.0 3.4e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase LEM PF03020.15 OEU21559.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 LEM domain Glyco_transf_49 PF13896.6 OEU21559.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan HA PF03457.14 OEU21560.1 - 1.4e-32 111.8 4.4 1.7e-15 57.1 0.0 2.8 3 0 0 3 3 3 2 Helicase associated domain Gly_transf_sug PF04488.15 OEU21561.1 - 1.4e-08 35.2 0.2 6.1e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU21561.1 - 0.00016 21.1 0.2 0.0016 17.8 0.0 2.0 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain HA PF03457.14 OEU21562.1 - 8.3e-56 186.2 6.1 3.8e-19 68.8 0.4 3.0 3 0 0 3 3 3 3 Helicase associated domain Mhr1 PF12829.7 OEU21562.1 - 0.003 17.6 0.1 3.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Transcriptional regulation of mitochondrial recombination mRNA_cap_C PF03919.15 OEU21562.1 - 0.086 13.5 8.8 1.8 9.3 0.2 3.4 3 1 1 4 4 4 0 mRNA capping enzyme, C-terminal domain Antirestrict PF03230.13 OEU21562.1 - 0.13 12.3 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Antirestriction protein HA PF03457.14 OEU21563.1 - 3.6e-47 158.6 6.3 7.2e-19 67.9 0.3 3.1 3 0 0 3 3 3 3 Helicase associated domain Spo12 PF05032.12 OEU21563.1 - 7.4 6.6 8.3 19 5.3 1.1 2.8 2 0 0 2 2 2 0 Spo12 family Ferlin_C PF16165.5 OEU21564.1 - 0.00095 19.1 0.9 0.0024 17.8 0.9 1.6 1 0 0 1 1 1 1 Ferlin C-terminus Med19 PF10278.9 OEU21564.1 - 0.047 13.6 4.7 0.92 9.4 4.7 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.9 OEU21564.1 - 3.8 7.1 16.2 0.31 10.6 7.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-MYND PF01753.18 OEU21565.1 - 6e-10 39.0 13.9 1.4e-09 37.9 13.9 1.6 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 OEU21565.1 - 0.00027 20.8 0.3 0.42 10.9 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21565.1 - 0.00027 20.9 1.0 1.1 9.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21565.1 - 0.0017 18.1 0.6 0.31 10.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Phage_DsbA PF11126.8 OEU21565.1 - 0.034 14.3 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator DsbA Ubiq-assoc PF09145.10 OEU21565.1 - 0.13 12.3 0.5 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-associated zf-C6H2 PF15801.5 OEU21565.1 - 0.14 12.5 9.4 0.38 11.1 9.4 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Zn_ribbon_SprT PF17283.2 OEU21565.1 - 0.18 11.8 4.8 0.58 10.1 4.8 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 OEU21565.1 - 7 6.8 9.2 60 3.8 9.2 2.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 GSP_synth PF03738.14 OEU21566.1 - 0.038 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp LacI PF00356.21 OEU21566.1 - 0.063 13.1 0.3 0.47 10.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family MFS_1 PF07690.16 OEU21567.1 - 9.3e-19 67.6 1.4 2.9e-14 52.8 0.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Plasmod_dom_1 PF09715.10 OEU21567.1 - 0.054 13.6 1.3 7.9 6.6 0.0 3.8 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF4484 PF14831.6 OEU21567.1 - 1.7 8.7 7.7 0.93 9.5 5.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) SpoIIIAH PF12685.7 OEU21567.1 - 2 8.2 21.0 0.051 13.4 11.9 2.5 3 0 0 3 3 3 0 SpoIIIAH-like protein SMYLE_N PF18615.1 OEU21567.1 - 6.4 6.2 7.5 13 5.2 7.5 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pinin_SDK_memA PF04696.13 OEU21568.1 - 0.049 13.7 19.9 0.078 13.0 19.9 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DDRGK PF09756.9 OEU21568.1 - 0.056 13.0 16.7 0.069 12.7 16.7 1.1 1 0 0 1 1 1 0 DDRGK domain Ribosomal_S8e PF01201.22 OEU21568.1 - 0.28 11.3 4.5 0.36 11.0 4.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e CDC27 PF09507.10 OEU21568.1 - 0.37 10.1 14.2 0.55 9.6 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GBP_C PF02841.14 OEU21568.1 - 0.53 9.6 12.7 0.61 9.4 12.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Sec62 PF03839.16 OEU21568.1 - 3 7.3 6.6 3.4 7.1 6.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 U1snRNP70_N PF12220.8 OEU21568.1 - 3.8 8.2 9.2 11 6.8 9.2 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Presenilin PF01080.17 OEU21568.1 - 4.1 6.1 6.6 4.1 6.1 6.6 1.1 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 OEU21568.1 - 8.1 5.5 17.0 10 5.2 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF89 PF01937.19 OEU21569.1 - 2.4e-71 240.6 1.1 3.3e-65 220.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF89 Pertus-S5-tox PF09276.10 OEU21569.1 - 0.14 12.2 0.1 2.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Pertussis toxin S5 subunit Rieske PF00355.26 OEU21570.1 - 5.5e-11 42.3 0.0 7.9e-10 38.5 0.0 2.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 OEU21570.1 - 3.5e-07 30.3 0.2 2.5e-06 27.5 0.2 2.2 1 1 0 1 1 1 1 Pheophorbide a oxygenase Rad50_zn_hook PF04423.14 OEU21570.1 - 0.086 12.7 0.2 0.26 11.2 0.2 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif YdjO PF14169.6 OEU21570.1 - 0.16 11.8 0.9 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO DUF760 PF05542.11 OEU21571.1 - 3.5e-26 91.4 0.0 1.8e-14 53.8 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF760) EF-hand_7 PF13499.6 OEU21571.1 - 4.3e-11 43.1 2.2 4.3e-11 43.1 2.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU21571.1 - 1.3e-10 40.3 0.7 0.00065 19.4 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU21571.1 - 3.2e-09 35.9 2.7 2e-05 23.9 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 OEU21571.1 - 4.3e-09 35.3 2.5 7.3e-05 22.0 0.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OEU21571.1 - 1.3e-08 34.6 1.2 0.00042 20.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair DUF2442 PF10387.9 OEU21571.1 - 0.025 14.9 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Fer2 PF00111.27 OEU21572.1 - 3.5e-05 23.7 0.8 0.0002 21.3 0.8 2.3 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 7tm_3 PF00003.22 OEU21575.1 - 5.1e-37 127.9 22.8 5.1e-37 127.9 22.8 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 OEU21575.1 - 7e-20 72.0 0.1 1.1e-19 71.4 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 OEU21575.1 - 0.037 13.1 0.4 0.16 11.0 0.4 2.0 1 1 0 1 1 1 0 Receptor family ligand binding region SAP PF02037.27 OEU21579.1 - 2.5e-07 30.3 2.7 4.3e-07 29.5 2.7 1.4 1 0 0 1 1 1 1 SAP domain Rep_fac-A_3 PF08661.11 OEU21579.1 - 0.68 10.3 5.1 1.6 9.2 4.3 2.1 1 1 0 1 1 1 0 Replication factor A protein 3 FAM176 PF14851.6 OEU21579.1 - 0.93 9.1 11.3 2.2 7.9 1.5 3.7 4 0 0 4 4 4 0 FAM176 family BRX_N PF13713.6 OEU21580.1 - 0.023 14.4 0.8 0.047 13.5 0.8 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Peptidase_M11 PF05548.11 OEU21581.1 - 2.5e-09 36.7 0.2 5.6e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_4 PF13583.6 OEU21581.1 - 0.00021 21.0 0.1 0.00021 21.0 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OEU21581.1 - 0.0095 15.8 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 OEU21581.1 - 0.03 14.8 1.0 0.17 12.4 0.0 2.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like PT PF04886.12 OEU21581.1 - 0.04 13.5 109.0 0.23 11.0 25.0 5.5 3 1 2 5 5 5 0 PT repeat Peptidase_M54 PF07998.11 OEU21581.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 ANAPC_CDC26 PF10471.9 OEU21581.1 - 1.6 9.6 12.2 3.1 8.7 3.3 3.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF383 PF04063.14 OEU21583.1 - 0.048 13.3 0.0 29 4.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF383) Acyltransferase PF01553.21 OEU21585.1 - 6.8e-14 51.6 0.0 1.1e-12 47.7 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DUF2457 PF10446.9 OEU21585.1 - 1.4 8.0 9.2 2.2 7.4 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SpoU_methylase PF00588.19 OEU21586.1 - 2.4e-24 86.1 0.0 3.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Dirigent PF03018.14 OEU21587.1 - 0.03 14.1 0.4 0.061 13.1 0.4 1.4 1 0 0 1 1 1 0 Dirigent-like protein Cu-oxidase_2 PF07731.14 OEU21588.1 - 3.2e-41 140.3 3.7 2e-36 124.8 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OEU21588.1 - 7.6e-36 123.6 0.0 7.9e-35 120.3 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OEU21588.1 - 5.2e-32 110.4 2.0 1.6e-30 105.5 0.2 3.1 3 0 0 3 3 3 1 Multicopper oxidase DAGK_cat PF00781.24 OEU21589.1 - 0.004 16.8 0.7 0.7 9.5 0.1 2.8 2 1 1 3 3 3 2 Diacylglycerol kinase catalytic domain Chloroa_b-bind PF00504.21 OEU21590.1 - 2.7e-38 132.0 0.0 3.6e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CNDH2_C PF16858.5 OEU21591.1 - 3.7e-08 33.6 0.0 4.8e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_C PF16858.5 OEU21592.1 - 0.00018 21.5 0.0 0.00018 21.5 0.0 2.4 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mito_carr PF00153.27 OEU21594.1 - 3.8e-55 183.8 0.4 4.4e-18 65.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Clr2 PF10383.9 OEU21595.1 - 0.066 14.0 1.3 0.13 13.1 1.3 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DZR PF12773.7 OEU21595.1 - 0.075 13.1 1.5 0.18 11.9 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU21595.1 - 0.11 12.3 0.6 0.24 11.2 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain CHASE3 PF05227.13 OEU21595.1 - 0.21 11.5 6.6 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 CHASE3 domain SapC PF07277.11 OEU21595.1 - 1.3 8.5 5.7 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 SapC DUF1965 PF09248.10 OEU21596.1 - 0.041 13.7 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Herpes_glycop PF01528.16 OEU21596.1 - 0.11 11.3 6.1 0.15 10.9 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PRT_C PF08372.10 OEU21596.1 - 0.81 9.4 5.3 0.96 9.2 1.8 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal zf-TAZ PF02135.16 OEU21597.1 - 8.6e-15 55.0 21.2 9.7e-15 54.8 21.2 1.0 1 0 0 1 1 1 1 TAZ zinc finger AZUL PF16558.5 OEU21597.1 - 7.4 6.9 14.9 15 5.9 8.3 2.3 1 1 1 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Bromodomain PF00439.25 OEU21598.1 - 8.8e-18 64.2 0.0 1.3e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain HAT_KAT11 PF08214.11 OEU21599.1 - 4.1e-28 98.7 0.3 1.6e-27 96.7 0.2 1.9 2 0 0 2 2 2 1 Histone acetylation protein zf-TAZ PF02135.16 OEU21599.1 - 6.1e-11 42.6 13.7 6.1e-11 42.6 13.7 3.9 3 1 0 3 3 3 1 TAZ zinc finger ZZ PF00569.17 OEU21599.1 - 2.5e-06 27.2 5.1 2.5e-06 27.2 5.1 3.9 4 0 0 4 4 4 1 Zinc finger, ZZ type DUF902 PF06001.13 OEU21599.1 - 2.3e-05 24.8 1.0 0.00014 22.2 1.0 2.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) PHD PF00628.29 OEU21599.1 - 0.00034 20.5 3.9 0.00034 20.5 3.9 5.5 5 1 0 5 5 5 1 PHD-finger PHD_2 PF13831.6 OEU21599.1 - 2.6 7.7 14.2 0.17 11.5 5.7 3.6 3 0 0 3 3 3 0 PHD-finger COPIIcoated_ERV PF07970.12 OEU21600.1 - 6.3e-06 26.2 0.1 7.8e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter DUF3938 PF13074.6 OEU21600.1 - 0.11 12.8 1.5 0.19 12.0 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3938) RXT2_N PF08595.11 OEU21601.1 - 4.7 7.2 26.9 0.29 11.2 6.9 3.5 2 1 2 4 4 4 0 RXT2-like, N-terminal Amastin PF07344.11 OEU21602.1 - 0.0031 17.4 14.9 0.034 14.0 5.4 2.2 1 1 1 2 2 2 2 Amastin surface glycoprotein CTV_P6 PF06706.11 OEU21602.1 - 2.1 8.1 6.0 0.57 9.9 1.6 2.2 1 1 1 2 2 2 0 Citrus tristeza virus 6-kDa protein Dirigent PF03018.14 OEU21603.1 - 0.002 17.9 0.1 0.0046 16.8 0.1 1.6 1 0 0 1 1 1 1 Dirigent-like protein HTH_1 PF00126.27 OEU21604.1 - 0.059 13.3 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_ner PF04546.13 OEU21604.1 - 0.32 10.8 1.7 2 8.3 0.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region HSF_DNA-bind PF00447.17 OEU21605.1 - 7.7e-10 39.3 0.1 7.7e-10 39.3 0.1 3.2 4 0 0 4 4 4 1 HSF-type DNA-binding Asn_synthase PF00733.21 OEU21607.1 - 8.4e-07 29.0 0.1 5.8e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 Asparagine synthase QueC PF06508.13 OEU21607.1 - 0.007 15.9 0.2 0.047 13.2 0.2 2.3 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Phage_Gp23 PF10669.9 OEU21607.1 - 5.4 7.4 9.5 34 4.8 0.2 2.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) HA PF03457.14 OEU21608.1 - 2.7e-71 235.8 21.2 1.6e-14 53.9 0.7 5.0 5 0 0 5 5 5 5 Helicase associated domain Ribosomal_L7Ae PF01248.26 OEU21608.1 - 0.0003 20.5 0.2 8.7 6.2 0.0 4.3 5 0 0 5 5 5 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3836 PF12930.7 OEU21608.1 - 0.0041 16.9 8.0 1.5 8.6 0.3 4.1 4 1 0 4 4 4 2 Family of unknown function (DUF3836) Endonuclease_1 PF04231.13 OEU21610.1 - 8.9e-16 58.3 0.1 3.1e-15 56.5 0.1 2.0 1 0 0 1 1 1 1 Endonuclease I Apt1 PF10351.9 OEU21611.1 - 4.5 6.0 12.8 4.9 5.9 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Methyltransf_22 PF13383.6 OEU21614.1 - 5.5e-32 111.3 6.1 6.8e-31 107.7 1.5 2.3 2 0 0 2 2 2 2 Methyltransferase domain SspO PF08175.12 OEU21614.1 - 0.029 14.8 0.5 0.084 13.4 0.5 1.8 1 0 0 1 1 1 0 Small acid-soluble spore protein O family Chalcone_2 PF16035.5 OEU21614.1 - 0.098 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Chalcone isomerase like DUF2987 PF11205.8 OEU21616.1 - 0.013 15.4 1.7 0.013 15.4 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) Transketolase_N PF00456.21 OEU21617.1 - 9.1e-139 462.1 0.0 3.8e-138 460.0 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OEU21617.1 - 8.2e-37 126.6 0.1 3.3e-36 124.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OEU21617.1 - 8.5e-09 35.4 0.0 2.2e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OEU21617.1 - 0.0053 16.0 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase HA PF03457.14 OEU21618.1 - 5.7e-100 327.7 15.3 3e-20 72.3 0.1 5.1 5 0 0 5 5 5 5 Helicase associated domain Antirestrict PF03230.13 OEU21618.1 - 0.00023 21.1 2.0 13 5.9 0.0 5.0 5 0 0 5 5 5 1 Antirestriction protein DUF5049 PF16468.5 OEU21618.1 - 0.0055 16.6 3.4 13 5.8 0.1 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF5049) IFP_35_N PF07334.13 OEU21618.1 - 0.0066 16.5 0.0 0.21 11.7 0.0 2.9 3 0 0 3 3 3 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7_C2 PF15577.6 OEU21618.1 - 0.087 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Spc7_C2 CRF1 PF10380.9 OEU21618.1 - 0.13 12.6 0.2 71 3.8 0.0 4.2 5 0 0 5 5 5 0 Transcription factor CRF1 RNase_3_N PF18497.1 OEU21618.1 - 0.29 11.4 6.6 35 4.7 0.0 4.2 5 0 0 5 5 5 0 Ribonuclease III N-terminal domain PMR5N PF14416.6 OEU21618.1 - 0.37 11.2 6.1 1.8e+02 2.5 0.1 5.4 5 1 1 6 6 6 0 PMR5 N terminal Domain LPD22 PF18834.1 OEU21618.1 - 0.85 9.9 4.2 1.1e+02 3.1 0.0 4.4 5 0 0 5 5 5 0 Large polyvalent protein associated domain 22 Myb_DNA-binding PF00249.31 OEU21619.1 - 8.4e-18 64.3 0.7 6.6e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU21619.1 - 3.2e-15 56.1 4.0 4.3e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HA PF03457.14 OEU21620.1 - 1.3e-69 230.5 9.3 6.2e-16 58.5 0.2 6.4 6 0 0 6 6 6 6 Helicase associated domain CortBP2 PF09727.9 OEU21620.1 - 0.39 10.6 5.1 2 8.3 4.7 2.2 2 0 0 2 2 2 0 Cortactin-binding protein-2 Fer4_4 PF12800.7 OEU21622.1 - 0.44 11.2 0.6 0.44 11.2 0.6 3.6 3 1 0 3 3 3 0 4Fe-4S binding domain Peptidase_M11 PF05548.11 OEU21623.1 - 6.1e-05 22.3 6.9 0.0005 19.3 6.8 2.3 1 1 0 1 1 1 1 Gametolysin peptidase M11 Sulfotransfer_3 PF13469.6 OEU21623.1 - 0.00093 19.6 0.0 0.41 11.0 0.0 2.8 2 0 0 2 2 2 2 Sulfotransferase family SVA PF05326.11 OEU21623.1 - 0.062 13.3 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) DUF3357 PF11837.8 OEU21623.1 - 0.077 13.5 0.1 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Trypan_PARP PF05887.11 OEU21623.1 - 0.53 10.3 27.9 0.06 13.3 19.2 3.3 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Phytase-like PF13449.6 OEU21624.1 - 3.4e-39 135.5 0.4 2e-38 133.0 0.2 2.3 3 0 0 3 3 3 1 Esterase-like activity of phytase NHL PF01436.21 OEU21624.1 - 6.1e-05 22.9 4.4 1.6 8.9 0.1 5.6 5 0 0 5 5 5 2 NHL repeat LVIVD PF08309.11 OEU21624.1 - 0.0095 15.2 0.6 1 8.7 0.1 2.9 2 0 0 2 2 2 2 LVIVD repeat CPSF_A PF03178.15 OEU21624.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 CPSF A subunit region RVT_2 PF07727.14 OEU21625.1 - 4.2e-05 23.3 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OEU21625.1 - 0.025 14.8 0.1 0.061 13.5 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain Nucleoside_tran PF01733.18 OEU21626.1 - 0.011 15.1 0.2 0.029 13.7 0.0 1.6 2 0 0 2 2 2 0 Nucleoside transporter Orf78 PF06024.12 OEU21626.1 - 0.013 15.8 1.8 0.013 15.8 1.8 3.0 2 2 0 2 2 2 0 Orf78 (ac78) Shisa PF13908.6 OEU21626.1 - 0.018 15.3 2.4 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.6 OEU21626.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF2335 PF10097.9 OEU21626.1 - 0.55 10.2 3.4 3 7.9 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) DUF3439 PF11921.8 OEU21626.1 - 6 6.9 10.0 1.3 9.0 6.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) MFS_1 PF07690.16 OEU21627.1 - 1.3e-10 40.8 23.0 1.7e-10 40.4 23.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OEU21627.1 - 0.068 12.0 7.8 0.086 11.7 7.8 1.2 1 0 0 1 1 1 0 MFS_1 like family Lipase_3 PF01764.25 OEU21629.1 - 2.2e-05 24.3 0.0 5.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) PqiA PF04403.13 OEU21630.1 - 3e-14 53.1 15.0 1.5e-08 34.7 4.8 2.8 2 0 0 2 2 2 2 Paraquat-inducible protein A SelK_SelG PF10961.8 OEU21630.1 - 0.045 14.4 0.1 2.4 8.9 0.0 3.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG SUIM_assoc PF16619.5 OEU21630.1 - 0.1 12.7 1.5 0.33 11.0 1.5 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Orf78 PF06024.12 OEU21630.1 - 4.9 7.5 10.5 0.29 11.5 0.4 4.4 3 1 1 4 4 4 0 Orf78 (ac78) DnaJ PF00226.31 OEU21631.1 - 0.00012 22.1 0.1 0.17 12.1 0.0 2.6 2 0 0 2 2 2 2 DnaJ domain G-patch PF01585.23 OEU21632.1 - 4.9e-11 42.3 1.1 1.1e-10 41.2 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OEU21632.1 - 2.4e-05 24.4 3.4 3.3e-05 23.9 1.2 2.1 2 0 0 2 2 2 1 G-patch domain GHMP_kinases_N PF00288.26 OEU21632.1 - 0.16 12.2 2.4 3.6 7.9 0.8 2.9 2 2 0 2 2 2 0 GHMP kinases N terminal domain PRAS PF15798.5 OEU21633.1 - 0.95 10.1 5.4 4.8 7.8 0.5 2.2 1 1 1 2 2 2 0 Proline-rich AKT1 substrate 1 DUF4746 PF15928.5 OEU21633.1 - 3 7.2 6.2 1.1 8.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4746) Endomucin PF07010.12 OEU21633.1 - 4.3 7.2 20.3 0.23 11.4 13.0 1.9 2 0 0 2 2 2 0 Endomucin UL42 PF17638.2 OEU21634.1 - 0.34 10.9 7.5 1.6 8.7 0.5 3.6 3 0 0 3 3 3 0 HCMV UL42 CRAL_TRIO PF00650.20 OEU21634.1 - 0.72 9.6 0.0 0.72 9.6 0.0 2.8 4 0 0 4 4 4 0 CRAL/TRIO domain 4HBT_3 PF13622.6 OEU21634.1 - 9.6 6.4 7.3 1.8 8.8 1.7 2.2 2 0 0 2 2 2 0 Thioesterase-like superfamily DUF2431 PF10354.9 OEU21635.1 - 7.9e-31 107.6 0.0 1.1e-30 107.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) z-alpha PF02295.17 OEU21635.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain EamA PF00892.20 OEU21636.1 - 4.6e-10 39.8 32.1 2.3e-07 31.1 15.4 2.3 2 1 0 2 2 2 2 EamA-like transporter family SipA_VBS PF17985.1 OEU21636.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 SipA vinculin binding site ABC2_membrane_3 PF12698.7 OEU21637.1 - 5.4 6.0 7.1 0.18 10.9 0.8 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Peptidase_M24 PF00557.24 OEU21638.1 - 6.2e-42 143.7 0.0 1.1e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OEU21638.1 - 1.1e-21 76.8 0.0 3e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Thioredoxin PF00085.20 OEU21640.1 - 2.3e-16 59.7 0.0 4.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 OEU21640.1 - 5.5e-13 48.7 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 PUB domain Thioredoxin_7 PF13899.6 OEU21640.1 - 0.0025 17.9 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU21640.1 - 0.0045 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 OEU21640.1 - 0.018 14.8 0.0 1.1 9.0 0.0 3.5 4 1 1 5 5 5 0 Redoxin Thioredoxin_8 PF13905.6 OEU21640.1 - 0.019 15.3 0.0 0.082 13.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin PF00085.20 OEU21641.1 - 3.3e-16 59.1 0.0 8.8e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 OEU21641.1 - 7e-13 48.3 0.0 2.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 PUB domain Thioredoxin_7 PF13899.6 OEU21641.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU21641.1 - 0.0064 16.9 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU21641.1 - 0.035 14.4 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like UBA PF00627.31 OEU21641.1 - 0.073 13.0 0.1 0.073 13.0 0.1 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Thioredoxin PF00085.20 OEU21642.1 - 4.1e-16 58.8 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 OEU21642.1 - 8.8e-13 48.0 0.0 2.5e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 PUB domain Thioredoxin_7 PF13899.6 OEU21642.1 - 0.0045 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU21642.1 - 0.0077 16.7 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU21642.1 - 0.041 14.2 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like UBA PF00627.31 OEU21642.1 - 0.085 12.8 0.1 0.085 12.8 0.1 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Thioredoxin PF00085.20 OEU21643.1 - 8.6e-17 61.0 0.0 9.4e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU21643.1 - 0.00025 21.2 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU21643.1 - 0.00077 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU21643.1 - 0.0029 17.9 0.0 0.006 16.9 0.0 1.4 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OEU21643.1 - 0.0069 16.1 0.0 0.075 12.7 0.0 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 OEU21643.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.6 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.6 OEU21643.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Mito_carr PF00153.27 OEU21644.1 - 8.3e-41 137.8 3.9 8.2e-14 51.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OEU21644.1 - 0.0061 16.9 4.2 0.025 14.9 1.4 2.5 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ThrE_2 PF12821.7 OEU21644.1 - 1.7 8.8 7.2 7.5 6.7 2.0 2.9 3 0 0 3 3 3 0 Threonine/Serine exporter, ThrE Mito_carr PF00153.27 OEU21645.1 - 7.1e-41 138.1 3.9 7.7e-14 51.4 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OEU21645.1 - 0.0061 16.9 4.3 0.027 14.8 1.5 2.5 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ThrE_2 PF12821.7 OEU21645.1 - 1.7 8.8 7.2 7.2 6.8 2.0 2.9 3 0 0 3 3 3 0 Threonine/Serine exporter, ThrE SelR PF01641.18 OEU21646.1 - 9.4e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 1 0 1 1 1 1 SelR domain Ribonuc_red_sm PF00268.21 OEU21647.1 - 2.3e-110 368.5 0.0 3.1e-110 368.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Fe_bilin_red PF05996.12 OEU21648.1 - 8.1e-56 189.2 2.1 9.8e-56 189.0 1.2 1.5 2 0 0 2 2 2 1 Ferredoxin-dependent bilin reductase FPN1 PF06963.12 OEU21649.1 - 5.4e-91 305.3 13.5 6.5e-69 232.6 3.6 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Shikimate_dh_N PF08501.11 OEU21650.1 - 2.9e-22 78.7 0.1 4.6e-21 74.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 OEU21650.1 - 2.5e-20 73.7 0.0 6.9e-20 72.3 0.0 1.7 1 1 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 OEU21650.1 - 1e-08 34.8 0.6 2.5e-08 33.5 0.6 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OEU21650.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OEU21650.1 - 0.022 15.3 0.0 0.08 13.5 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DHQ_synthase PF01761.20 OEU21651.1 - 1.1e-60 205.0 0.0 1.5e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OEU21651.1 - 7.9e-10 38.9 0.0 5.3e-09 36.1 0.0 2.0 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 OEU21651.1 - 0.00012 21.0 0.0 0.00026 19.9 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase URO-D PF01208.17 OEU21652.1 - 3.8e-95 319.0 0.0 4.5e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) YnfE PF17452.2 OEU21652.1 - 0.009 16.3 0.2 0.022 15.0 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized YnfE-like DUF1043 PF06295.12 OEU21652.1 - 0.086 12.9 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FAD_binding_3 PF01494.19 OEU21653.1 - 1.3e-10 41.1 0.1 4e-06 26.3 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 OEU21653.1 - 0.001 18.0 0.0 0.21 10.4 0.0 2.5 2 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 OEU21653.1 - 0.0038 17.2 0.0 2.3 8.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OEU21653.1 - 0.007 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OEU21653.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU21653.1 - 0.015 14.9 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU21653.1 - 0.033 14.4 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OEU21653.1 - 0.067 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein PAS_9 PF13426.7 OEU21654.1 - 7.7e-17 61.5 0.0 1.9e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain bZIP_1 PF00170.21 OEU21654.1 - 1.5e-08 34.6 5.7 3.1e-08 33.6 5.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU21654.1 - 1.7e-08 34.4 9.3 3.3e-08 33.5 9.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PAS_3 PF08447.12 OEU21654.1 - 0.0004 20.6 0.0 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OEU21654.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold bZIP_Maf PF03131.17 OEU21654.1 - 0.013 16.0 2.8 0.024 15.1 2.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor HAP1_N PF04849.13 OEU21654.1 - 0.024 13.8 0.8 0.035 13.3 0.8 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Rubis-subs-bind PF09273.11 OEU21655.1 - 1.1e-08 35.8 0.6 3e-08 34.4 0.3 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 OEU21655.1 - 0.00012 22.6 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 SET domain MCD PF05292.11 OEU21656.1 - 1.6e-67 227.8 0.4 3.7e-67 226.6 0.4 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 OEU21656.1 - 3.3e-06 27.1 0.2 3e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain Mem_trans PF03547.18 OEU21656.1 - 0.087 11.2 2.2 0.18 10.2 2.2 1.7 1 0 0 1 1 1 0 Membrane transport protein Host_attach PF10116.9 OEU21656.1 - 0.53 10.9 2.1 1.8 9.2 0.4 2.7 2 1 1 3 3 3 0 Protein required for attachment to host cells Acyl_transf_1 PF00698.21 OEU21657.1 - 6.5e-24 85.0 0.3 8.8e-24 84.6 0.3 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 OEU21657.1 - 0.0007 19.4 0.1 0.019 14.7 0.1 2.3 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FA_desaturase PF00487.24 OEU21658.1 - 9.3e-12 45.3 21.5 1.4e-11 44.7 21.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Phyto_Pns9_10 PF05878.11 OEU21658.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 PGI PF00342.19 OEU21659.1 - 3.8e-136 454.5 0.0 1.8e-122 409.4 0.0 3.0 2 1 0 2 2 2 2 Phosphoglucose isomerase GDP_Man_Dehyd PF16363.5 OEU21660.1 - 3.1e-50 171.4 0.0 8.9e-50 170.0 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU21660.1 - 6.3e-46 156.8 0.1 8e-46 156.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU21660.1 - 3.1e-17 62.5 0.0 4.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU21660.1 - 6.4e-12 45.2 0.0 1.1e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU21660.1 - 7.2e-10 38.4 0.0 9.1e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OEU21660.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OEU21660.1 - 0.002 17.3 0.8 0.0088 15.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 OEU21660.1 - 0.0062 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 OEU21660.1 - 0.08 12.5 0.4 0.18 11.3 0.4 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.23 OEU21660.1 - 0.13 12.4 0.5 0.32 11.1 0.5 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Gag_MA PF01140.19 OEU21660.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Matrix protein (MA), p15 DUF3494 PF11999.8 OEU21661.1 - 2.4e-50 171.1 20.2 3.1e-50 170.7 20.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Aha1_N PF09229.11 OEU21661.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal tRNA_SAD PF07973.14 OEU21662.1 - 3.4e-11 43.1 0.0 7.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2b PF00587.25 OEU21662.1 - 2.7e-09 37.3 0.3 6.7e-09 36.0 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) TGS PF02824.21 OEU21662.1 - 0.0016 18.5 0.0 0.0059 16.6 0.0 1.9 2 0 0 2 2 2 1 TGS domain Inhibitor_G39P PF11417.8 OEU21662.1 - 0.21 12.2 2.4 25 5.5 0.0 2.8 3 0 0 3 3 3 0 Loader and inhibitor of phage G40P KELK PF15796.5 OEU21662.1 - 3.3 8.2 8.9 0.11 12.9 2.4 1.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TRAP_alpha PF03896.16 OEU21663.1 - 0.27 10.4 7.6 0.039 13.1 3.6 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4293 PF14126.6 OEU21663.1 - 3.9 7.7 14.9 33 4.7 15.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DNA_pol_phi PF04931.13 OEU21663.1 - 7.4 4.5 12.9 11 4.0 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi FRD2 PF03197.13 OEU21665.1 - 0.057 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Sulfotransfer_4 PF17784.1 OEU21667.1 - 0.0017 18.2 0.1 0.0052 16.7 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Dak2 PF02734.17 OEU21668.1 - 1.4e-20 73.9 0.0 3.6e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 DAK2 domain Dak1_2 PF13684.6 OEU21668.1 - 5.2e-11 42.2 0.0 8.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Thioredoxin PF00085.20 OEU21669.1 - 1.9e-29 101.6 0.3 2.2e-29 101.5 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU21669.1 - 3.9e-09 36.9 0.2 5.7e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU21669.1 - 1.5e-07 31.2 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OEU21669.1 - 2.1e-07 30.6 0.0 2.3e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OEU21669.1 - 6.5e-06 26.1 0.1 7.8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OEU21669.1 - 1.1e-05 25.7 0.0 1.7e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU21669.1 - 0.00011 21.9 0.3 0.00022 20.9 0.3 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OEU21669.1 - 0.0019 18.3 0.2 0.0035 17.5 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.16 OEU21669.1 - 0.0026 17.6 0.0 0.0027 17.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 OEU21669.1 - 0.015 15.5 0.1 0.024 14.8 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 OEU21669.1 - 0.026 14.4 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 OEU21669.1 - 0.09 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE HSP20 PF00011.21 OEU21670.1 - 0.0012 18.9 0.5 0.0033 17.5 0.5 1.7 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Phostensin_N PF13916.6 OEU21670.1 - 0.043 14.2 0.8 0.043 14.2 0.8 1.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Guanylate_cyc PF00211.20 OEU21671.1 - 6.5e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FA_desaturase PF00487.24 OEU21672.1 - 8.4e-13 48.7 8.6 3.6e-12 46.7 8.6 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3894 PF13033.6 OEU21673.1 - 0.36 11.0 2.5 1.4 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) PD40 PF07676.12 OEU21674.1 - 3.9e-06 26.6 4.2 0.00019 21.3 0.6 2.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 OEU21674.1 - 3.2e-05 24.6 0.8 0.00031 21.5 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OEU21674.1 - 0.037 13.0 0.0 5.7 5.8 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-MYND PF01753.18 OEU21675.1 - 2.7e-09 36.9 13.1 2.7e-09 36.9 13.1 3.1 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 OEU21675.1 - 2.9 8.0 13.0 0.43 10.7 7.1 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 LRR_4 PF12799.7 OEU21676.1 - 0.014 15.8 11.7 1.2 9.7 0.5 4.4 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU21676.1 - 0.13 12.9 3.6 1.4e+02 3.7 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat SpoU_methylase PF00588.19 OEU21678.1 - 2.7e-21 76.2 0.1 3.7e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family TPX2 PF06886.11 OEU21678.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) LRR_8 PF13855.6 OEU21679.1 - 0.12 12.2 1.3 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat Hira PF07569.11 OEU21680.1 - 1.9e-19 70.3 1.3 1.3e-14 54.5 0.1 4.6 3 0 0 3 3 3 2 TUP1-like enhancer of split WD40 PF00400.32 OEU21680.1 - 1.5e-17 63.7 17.4 0.00031 21.5 0.1 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU21680.1 - 2.7e-05 24.4 0.1 9.2 6.7 0.0 6.2 5 1 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 OEU21680.1 - 0.00039 19.9 0.1 0.016 14.6 0.0 2.5 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region HIRA_B PF09453.10 OEU21680.1 - 0.0098 15.7 0.1 0.034 14.0 0.1 1.9 1 0 0 1 1 1 1 HIRA B motif Ank_2 PF12796.7 OEU21681.1 - 1.8e-35 121.4 6.3 6.9e-07 29.8 0.1 8.4 6 2 4 10 10 10 8 Ankyrin repeats (3 copies) Ank PF00023.30 OEU21681.1 - 3.3e-31 106.3 18.1 0.0062 16.9 0.5 13.6 12 1 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.6 OEU21681.1 - 6.8e-25 87.1 9.4 7.7e-05 23.2 0.1 10.1 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU21681.1 - 3.2e-24 82.3 16.2 0.035 14.6 0.0 12.7 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 OEU21681.1 - 5.3e-19 68.0 17.4 0.0027 18.0 0.2 12.1 10 3 3 13 13 13 5 Ankyrin repeats (many copies) AP3D1 PF06375.11 OEU21682.1 - 0.0021 18.3 4.9 0.0021 18.3 4.9 3.8 4 1 0 4 4 4 2 AP-3 complex subunit delta-1 DUF3850 PF12961.7 OEU21682.1 - 0.1 12.7 0.5 0.21 11.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) DUF3439 PF11921.8 OEU21684.1 - 0.86 9.6 7.7 1.9 8.5 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PRIMA1 PF16101.5 OEU21685.1 - 0.15 12.1 6.6 0.38 10.8 3.7 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Ribosomal_60s PF00428.19 OEU21685.1 - 5.1 7.7 16.8 19 5.9 0.4 4.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Chloroa_b-bind PF00504.21 OEU21686.1 - 6.3e-38 130.8 0.1 9.6e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein MSP1_C PF07462.11 OEU21686.1 - 9 4.9 5.6 12 4.5 5.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Aldolase PF01081.19 OEU21687.1 - 0.053 12.9 5.9 18 4.7 3.7 3.4 1 1 1 2 2 2 0 KDPG and KHG aldolase WASH_WAHD PF11945.8 OEU21687.1 - 2 7.9 8.7 24 4.3 0.5 3.0 1 1 2 3 3 3 0 WAHD domain of WASH complex SAP PF02037.27 OEU21688.1 - 9e-11 41.3 2.1 9e-11 41.3 2.1 2.0 2 0 0 2 2 2 1 SAP domain DLH PF01738.18 OEU21688.1 - 4.6e-09 36.1 0.0 1.7e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Telomere_Sde2_2 PF13297.6 OEU21688.1 - 0.0077 15.9 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SPRY PF00622.28 OEU21689.1 - 0.069 13.3 2.3 0.082 13.0 0.2 2.3 2 0 0 2 2 2 0 SPRY domain PRIMA1 PF16101.5 OEU21689.1 - 0.28 11.2 9.2 0.95 9.5 9.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ATP_bind_1 PF03029.17 OEU21690.1 - 4.2e-73 246.1 0.3 6.3e-65 219.3 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OEU21690.1 - 0.002 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU21690.1 - 0.0089 16.3 0.0 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain FXR_C1 PF16096.5 OEU21690.1 - 0.011 16.0 3.6 0.02 15.1 3.6 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 AAA_18 PF13238.6 OEU21690.1 - 0.013 16.1 0.7 0.044 14.3 0.0 2.2 2 2 0 2 2 2 0 AAA domain SMC_N PF02463.19 OEU21690.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cytidylate_kin PF02224.18 OEU21690.1 - 0.054 13.2 0.3 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_16 PF13191.6 OEU21690.1 - 0.062 13.7 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OEU21690.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.6 OEU21690.1 - 0.2 11.6 0.4 15 5.4 0.1 2.8 2 1 1 3 3 3 0 AAA domain TAXi_N PF14543.6 OEU21691.1 - 2e-21 77.0 5.3 3.1e-21 76.4 5.3 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 OEU21691.1 - 2.5e-13 50.1 4.8 4.1e-09 36.3 1.4 3.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 OEU21691.1 - 0.017 14.9 0.1 0.066 13.0 0.1 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 OEU21692.1 - 2.4e-38 132.0 0.0 4.4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21692.1 - 1.3e-32 113.1 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU21692.1 - 0.0036 17.2 0.5 0.032 14.2 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family FAM76 PF16046.5 OEU21692.1 - 0.23 10.8 2.6 0.44 9.8 2.6 1.4 1 0 0 1 1 1 0 FAM76 protein BSD PF03909.17 OEU21693.1 - 8e-10 38.6 3.4 5.5e-08 32.7 0.6 2.8 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 OEU21693.1 - 0.00029 21.1 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Abi_C PF14355.6 OEU21693.1 - 0.061 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Abortive infection C-terminus Peptidase_C2 PF00648.21 OEU21693.1 - 0.12 11.3 0.1 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Calpain family cysteine protease Cnd1 PF12717.7 OEU21695.1 - 3.8e-50 170.1 4.4 4.9e-47 160.0 0.2 4.1 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OEU21695.1 - 0.0084 16.3 7.3 76 4.0 0.0 6.7 7 0 0 7 7 7 0 HEAT repeat DUF4042 PF13251.6 OEU21695.1 - 0.0099 15.6 0.1 1.9 8.1 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) UME PF08064.13 OEU21695.1 - 0.035 14.0 0.0 2.4 8.1 0.0 2.9 2 0 0 2 2 2 0 UME (NUC010) domain HEAT_EZ PF13513.6 OEU21695.1 - 0.039 14.5 0.7 1.1 9.8 0.0 4.1 3 1 1 4 4 4 0 HEAT-like repeat DUF3802 PF12290.8 OEU21695.1 - 0.057 13.9 0.0 0.37 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) RTP1_C1 PF10363.9 OEU21695.1 - 0.11 12.7 0.1 29 4.9 0.0 3.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Imm5 PF14423.6 OEU21695.1 - 3.7 7.7 11.5 0.12 12.6 3.8 2.4 2 0 0 2 2 2 0 Immunity protein Imm5 Drc1-Sld2 PF11719.8 OEU21696.1 - 0.0059 16.2 10.4 0.0059 16.2 10.4 1.9 2 0 0 2 2 2 1 DNA replication and checkpoint protein BUD22 PF09073.10 OEU21696.1 - 1 8.6 32.7 0.11 11.8 17.3 2.4 2 0 0 2 2 2 0 BUD22 zinc_ribbon_15 PF17032.5 OEU21696.1 - 1.5 9.6 5.8 29 5.5 0.6 3.5 3 0 0 3 3 3 0 zinc-ribbon family DUF2052 PF09747.9 OEU21696.1 - 1.6 8.8 17.2 0.27 11.3 9.3 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.7 OEU21696.1 - 2.7 6.0 6.7 4.1 5.4 6.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_tran PF00005.27 OEU21697.1 - 5e-08 33.5 0.2 1e-07 32.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter SbmA_BacA PF05992.12 OEU21697.1 - 1.3e-07 31.4 0.4 2.1e-07 30.7 0.3 1.4 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.15 OEU21697.1 - 6.3e-06 25.8 1.1 0.0033 16.9 0.0 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 RsgA_GTPase PF03193.16 OEU21697.1 - 0.00045 20.1 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 OEU21697.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OEU21697.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OEU21697.1 - 0.0017 18.0 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OEU21697.1 - 0.0037 17.1 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OEU21697.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 OEU21697.1 - 0.033 14.7 0.1 0.08 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OEU21697.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 OEU21697.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain OsmC PF02566.19 OEU21698.1 - 8.9e-07 29.3 0.1 7.6e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 OsmC-like protein DUF572 PF04502.13 OEU21699.1 - 4.3e-44 151.5 3.1 4.7e-44 151.4 3.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 OEU21699.1 - 0.069 13.0 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) LRR_4 PF12799.7 OEU21700.1 - 0.0043 17.4 0.4 4.4 7.9 0.0 4.8 4 1 3 7 7 7 1 Leucine Rich repeats (2 copies) LSM PF01423.22 OEU21701.1 - 4.4e-18 64.7 1.3 6.3e-18 64.2 1.3 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OEU21701.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Sec23_trunk PF04811.15 OEU21701.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Ribosomal_S6e PF01092.19 OEU21702.1 - 4e-53 178.7 0.6 4e-53 178.7 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e DUF410 PF04190.13 OEU21702.1 - 0.067 13.0 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF410) eRF1_1 PF03463.15 OEU21702.1 - 0.11 12.5 4.0 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 eRF1 domain 1 DUF4134 PF13572.6 OEU21703.1 - 0.044 14.1 4.0 2.8 8.3 0.7 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) FKBP_C PF00254.28 OEU21704.1 - 2.2e-10 40.7 0.1 4.6e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 OEU21705.1 - 9.3e-22 77.2 0.0 1.4e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 OEU21705.1 - 7.6e-08 32.7 0.2 1.6e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OEU21705.1 - 3.1e-06 26.3 1.8 0.017 14.6 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU21705.1 - 8.1e-05 22.2 0.5 0.57 10.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU21705.1 - 0.00016 21.0 2.4 0.0037 16.7 0.4 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OEU21705.1 - 0.02 14.7 1.3 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OEU21705.1 - 0.027 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3221 PF11518.8 OEU21705.1 - 0.053 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) RNA_pol_3_Rpc31 PF11705.8 OEU21706.1 - 0.0031 17.8 6.5 0.0042 17.4 6.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 IncFII_repA PF02387.15 OEU21706.1 - 0.057 12.7 0.2 0.074 12.3 0.2 1.1 1 0 0 1 1 1 0 IncFII RepA protein family DUF3984 PF13136.6 OEU21706.1 - 0.47 9.8 4.0 0.58 9.5 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) PBP1_TM PF14812.6 OEU21706.1 - 1.2 9.5 18.8 0.18 12.2 13.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rib PF08428.10 OEU21707.1 - 0.17 11.9 0.8 0.45 10.5 0.8 1.7 1 0 0 1 1 1 0 Rib/alpha-like repeat Tho1_MOS11_C PF18592.1 OEU21707.1 - 4.9 7.0 6.1 0.54 10.1 0.2 2.5 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain Comm PF15957.5 OEU21708.1 - 0.11 12.9 1.0 0.88 9.9 0.8 2.2 2 0 0 2 2 2 0 Commissureless NAD_binding_1 PF00175.21 OEU21709.1 - 8.1e-22 77.9 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU21709.1 - 4.3e-12 46.2 0.0 6.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OEU21709.1 - 0.00068 19.8 0.1 0.003 17.7 0.1 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF3244 PF11589.8 OEU21710.1 - 0.21 11.7 2.4 0.21 11.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) DUF2183 PF09949.9 OEU21711.1 - 3.9e-30 104.1 1.0 1.1e-28 99.5 0.3 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3871 PF12987.7 OEU21711.1 - 0.0058 15.5 0.2 0.01 14.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3871) Translin PF01997.16 OEU21712.1 - 6.8e-32 111.1 0.0 6.3e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 Translin family Med9 PF07544.13 OEU21712.1 - 0.066 13.3 1.8 1.2 9.2 0.2 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3391 PF11871.8 OEU21712.1 - 0.084 13.4 1.5 0.39 11.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4530 PF15039.6 OEU21712.1 - 0.089 12.9 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) CK2S PF15011.6 OEU21712.1 - 2 8.3 7.2 1.8 8.5 1.6 2.9 2 1 1 3 3 3 0 Casein Kinase 2 substrate Prefoldin_2 PF01920.20 OEU21712.1 - 2.4 8.1 9.8 11 6.0 0.6 3.2 2 1 0 2 2 2 0 Prefoldin subunit adh_short PF00106.25 OEU21713.1 - 6.2e-18 65.0 0.0 6e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU21713.1 - 4.3e-15 55.9 0.0 6e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase GTP1_OBG PF01018.22 OEU21713.1 - 0.069 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 GTP1/OBG LOR PF04525.12 OEU21718.1 - 5e-09 36.0 0.0 6.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 OEU21718.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 0 Scramblase Glutaredoxin PF00462.24 OEU21719.1 - 0.00012 22.3 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin PhyH PF05721.13 OEU21720.1 - 2e-13 51.1 0.0 2.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) tRNA_U5-meth_tr PF05958.11 OEU21721.1 - 7.2e-10 38.4 0.0 9e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OEU21721.1 - 1.2e-07 31.6 0.1 2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21721.1 - 4.5e-07 30.5 0.1 7.8e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OEU21721.1 - 7.3e-06 26.1 0.0 1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OEU21721.1 - 4.5e-05 23.1 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OEU21721.1 - 0.00012 22.7 0.0 0.00023 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OEU21721.1 - 0.0013 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OEU21721.1 - 0.0014 18.1 0.1 0.0018 17.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OEU21721.1 - 0.0014 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 OEU21721.1 - 0.0017 17.8 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 OEU21721.1 - 0.0029 17.0 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OEU21721.1 - 0.013 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 OEU21721.1 - 0.06 12.4 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme TPMT PF05724.11 OEU21721.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SR-25 PF10500.9 OEU21722.1 - 0.039 13.5 4.1 0.057 13.0 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Toprim_3 PF13362.6 OEU21723.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain IBR PF01485.21 OEU21724.1 - 4.6e-13 49.2 44.3 7.1e-07 29.4 12.9 5.0 3 2 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OEU21724.1 - 0.0083 16.1 3.3 0.0083 16.1 3.3 3.5 3 0 0 3 3 3 1 RING-type zinc-finger BTB PF00651.31 OEU21725.1 - 7.1e-13 48.8 0.1 4.5e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 OEU21725.1 - 0.017 15.2 0.2 1.4 9.0 0.0 2.5 1 1 1 2 2 2 0 BTB And C-terminal Kelch Nucleoporin_FG2 PF15967.5 OEU21725.1 - 0.082 11.4 16.1 0.11 11.0 16.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Peptidase_S9 PF00326.21 OEU21726.1 - 2.7e-05 23.7 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2457 PF10446.9 OEU21727.1 - 0.02 14.1 1.6 0.021 14.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VWA_2 PF13519.6 OEU21728.1 - 7.2e-16 58.8 0.7 5.4e-15 56.0 0.0 2.7 2 1 1 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 OEU21728.1 - 9.6e-05 22.0 22.6 0.015 15.2 3.9 4.1 3 0 0 3 3 3 3 Ubiquitin interaction motif YjeF_N PF03853.15 OEU21728.1 - 0.018 15.0 0.4 0.063 13.2 0.4 1.9 1 0 0 1 1 1 0 YjeF-related protein N-terminus Glycos_transf_1 PF00534.20 OEU21728.1 - 0.031 13.8 0.4 0.058 12.9 0.4 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF5550 PF17704.1 OEU21728.1 - 0.048 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5550) Spexin PF15171.6 OEU21728.1 - 1.1 9.5 4.4 3.8 7.8 1.5 2.9 2 1 1 3 3 3 0 Neuropeptide secretory protein family, NPQ, spexin Pkinase PF00069.25 OEU21729.1 - 2.1e-47 161.7 0.0 2.3e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21729.1 - 1.6e-27 96.5 0.0 1.9e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU21729.1 - 1.7e-07 30.8 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OEU21729.1 - 5.5e-06 25.4 0.0 6.8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OEU21729.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OEU21729.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PseudoU_synth_2 PF00849.22 OEU21730.1 - 4.9e-07 30.0 0.0 6.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase G_glu_transpept PF01019.21 OEU21732.1 - 1.5e-116 390.2 0.0 1.7e-116 390.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Sin_N PF04801.13 OEU21733.1 - 7.9e-43 147.3 4.4 2.8e-24 86.1 1.9 3.7 1 1 1 2 2 2 2 Sin-like protein conserved region KCNQ_channel PF03520.14 OEU21733.1 - 0.017 15.0 0.2 0.031 14.1 0.2 1.5 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel SAGA-Tad1 PF12767.7 OEU21733.1 - 0.11 12.3 1.0 0.18 11.5 1.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF5107 PF17128.4 OEU21734.1 - 1.3e-05 24.5 0.8 0.12 11.5 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF5107) GFA PF04828.14 OEU21735.1 - 2.5e-05 24.5 0.2 3.3e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 OEU21735.1 - 0.024 14.4 3.8 0.14 11.9 1.4 2.2 2 0 0 2 2 2 0 CSL zinc finger Spond_N PF06468.13 OEU21736.1 - 2e-33 116.1 0.2 2.8e-33 115.7 0.2 1.1 1 0 0 1 1 1 1 Spondin_N Toxin_12 PF07740.12 OEU21736.1 - 2.5 8.8 9.4 4.4 8.1 9.4 1.4 1 0 0 1 1 1 0 Ion channel inhibitory toxin Methyltransf_11 PF08241.12 OEU21737.1 - 2.3e-07 31.3 0.0 6.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21737.1 - 1.1e-06 28.6 0.0 8.4e-06 25.7 0.0 2.1 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21737.1 - 1.4e-05 25.8 0.0 4.6e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 OEU21737.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 OEU21737.1 - 0.087 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 OEU21737.1 - 0.13 13.0 0.1 0.67 10.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OEU21737.1 - 0.14 11.4 1.6 0.41 9.9 1.6 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 OEU21737.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 OEU21738.1 - 1.7e-07 31.8 0.0 4.5e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21738.1 - 3.1e-06 27.1 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21738.1 - 1.7e-05 25.5 0.0 4.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OEU21738.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 OEU21738.1 - 0.055 14.2 0.1 0.36 11.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain TPMT PF05724.11 OEU21738.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OEU21738.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain OCC1 PF15506.6 OEU21738.1 - 0.18 11.9 0.1 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 OCC1 family AAA_2 PF07724.14 OEU21739.1 - 5.1e-39 134.1 0.2 1.4e-32 113.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OEU21739.1 - 1.8e-13 51.1 0.0 3.5e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU21739.1 - 7.9e-08 32.4 0.2 0.00012 22.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 OEU21739.1 - 2.4e-06 27.5 0.8 9.2e-06 25.6 0.8 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 OEU21739.1 - 1.5e-05 25.4 2.0 5.4e-05 23.6 0.4 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OEU21739.1 - 4.1e-05 23.9 0.1 0.00051 20.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain MCM PF00493.23 OEU21739.1 - 9.4e-05 21.6 0.0 0.0098 15.0 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain G-alpha PF00503.20 OEU21739.1 - 0.00078 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Mg_chelatase PF01078.21 OEU21739.1 - 0.0019 17.6 0.8 0.018 14.4 0.0 2.9 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OEU21739.1 - 0.002 17.9 0.1 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_8 PF12780.7 OEU21739.1 - 0.0037 16.6 0.0 0.0081 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Sigma54_activat PF00158.26 OEU21739.1 - 0.004 16.9 0.0 0.049 13.3 0.0 2.5 3 0 0 3 3 3 1 Sigma-54 interaction domain TIP49 PF06068.13 OEU21739.1 - 0.0079 15.4 0.4 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 OEU21739.1 - 0.011 16.0 0.1 0.052 13.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 OEU21739.1 - 0.011 15.5 0.1 0.87 9.3 0.0 2.6 3 0 0 3 3 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 OEU21739.1 - 0.019 14.3 0.1 0.058 12.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family GyrB_insert PF18053.1 OEU21739.1 - 0.022 14.7 0.2 0.05 13.5 0.2 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain Zeta_toxin PF06414.12 OEU21739.1 - 0.023 14.0 0.0 0.066 12.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 OEU21739.1 - 0.028 14.9 0.1 0.44 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU21739.1 - 0.031 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OEU21739.1 - 0.033 13.6 0.0 0.092 12.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 OEU21739.1 - 0.064 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OEU21739.1 - 0.08 13.2 0.1 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU21739.1 - 0.097 12.6 0.0 2 8.3 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OEU21739.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OEU21739.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.9 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 OEU21739.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OEU21739.1 - 0.19 12.1 0.0 0.83 10.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase RFC1 PF08519.12 OEU21741.1 - 4.8e-30 104.8 0.1 1.4e-29 103.3 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain Macoilin PF09726.9 OEU21741.1 - 0.068 11.7 10.5 0.068 11.7 10.5 1.2 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 OEU21741.1 - 0.78 7.7 19.7 1.3 6.9 19.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Palm_thioest PF02089.15 OEU21742.1 - 2e-12 47.5 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Rrp44_CSD1 PF17216.3 OEU21742.1 - 0.058 13.1 0.3 0.081 12.7 0.3 1.1 1 0 0 1 1 1 0 Rrp44-like cold shock domain RFC1 PF08519.12 OEU21743.1 - 5.7e-39 133.8 0.0 1.3e-38 132.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 OEU21743.1 - 1.9e-15 57.5 0.0 2e-13 50.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OEU21743.1 - 4e-08 33.4 0.1 1.8e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 OEU21743.1 - 6.1e-07 29.4 0.0 0.00026 20.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_assoc_2 PF16193.5 OEU21743.1 - 0.00015 22.0 0.1 0.00056 20.2 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 OEU21743.1 - 0.00042 20.8 0.0 0.0016 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OEU21743.1 - 0.00049 19.9 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OEU21743.1 - 0.001 19.1 0.2 0.0063 16.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OEU21743.1 - 0.0032 17.7 0.0 0.012 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU21743.1 - 0.0033 16.7 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 OEU21743.1 - 0.025 15.0 0.1 0.15 12.5 0.1 2.4 1 1 0 1 1 1 0 RNA helicase DNA_pol3_delta PF06144.13 OEU21743.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Ribosomal_L7Ae PF01248.26 OEU21743.1 - 0.055 13.2 0.3 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_33 PF13671.6 OEU21743.1 - 0.057 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OEU21743.1 - 0.091 12.7 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 OEU21743.1 - 0.13 12.4 0.0 0.49 10.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OEU21743.1 - 0.16 12.0 0.1 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OEU21743.1 - 0.29 11.5 1.7 5.4 7.3 0.6 2.8 2 1 0 2 2 2 0 AAA domain Palm_thioest PF02089.15 OEU21744.1 - 2.6e-65 220.6 0.1 3.3e-65 220.3 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 OEU21744.1 - 0.048 13.5 0.5 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase RR_TM4-6 PF06459.12 OEU21745.1 - 0.019 14.8 12.2 0.024 14.5 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ApoLp-III PF07464.11 OEU21745.1 - 0.027 14.6 20.3 0.061 13.4 19.5 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.15 OEU21745.1 - 0.074 12.6 7.7 0.1 12.1 7.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4085 PF13315.6 OEU21745.1 - 0.17 11.5 8.2 0.27 10.8 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) AAA_13 PF13166.6 OEU21745.1 - 0.25 9.9 12.2 0.3 9.7 12.2 1.1 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 OEU21745.1 - 0.27 9.9 2.9 0.43 9.3 2.9 1.3 1 0 0 1 1 1 0 Presenilin DUF3810 PF12725.7 OEU21745.1 - 0.35 10.2 3.0 0.46 9.8 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Borrelia_P83 PF05262.11 OEU21745.1 - 0.38 9.2 21.8 0.5 8.8 21.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.13 OEU21745.1 - 0.54 9.5 10.0 0.84 8.8 10.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.11 OEU21745.1 - 0.89 7.4 9.0 1.2 7.0 9.0 1.1 1 0 0 1 1 1 0 Prominin ISG65-75 PF11727.8 OEU21745.1 - 1.1 8.5 16.6 1.7 7.8 16.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DBINO PF13892.6 OEU21745.1 - 1.5 9.2 24.8 0.25 11.7 20.7 1.7 2 0 0 2 2 2 0 DNA-binding domain BshC PF10079.9 OEU21745.1 - 1.7 7.3 11.9 2.4 6.8 11.9 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC TMCO5 PF14992.6 OEU21745.1 - 1.8 8.1 14.2 2.8 7.5 14.2 1.2 1 0 0 1 1 1 0 TMCO5 family ING PF12998.7 OEU21745.1 - 2.2 8.9 13.3 5.2 7.7 13.2 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Allexi_40kDa PF05549.11 OEU21745.1 - 2.5 7.5 5.4 4 6.9 5.4 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein OmpH PF03938.14 OEU21745.1 - 2.7 8.3 21.6 0.15 12.4 15.6 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) REF PF05755.12 OEU21745.1 - 3 7.6 14.0 0.65 9.8 8.1 2.1 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Sec2p PF06428.11 OEU21745.1 - 3.1 7.8 17.3 3.8 7.5 2.7 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ELL PF10390.9 OEU21745.1 - 3.9 6.9 13.6 6.4 6.2 13.6 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Fucose_iso_N2 PF07882.12 OEU21745.1 - 7 6.2 6.3 11 5.6 6.3 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain UQ_con PF00179.26 OEU21746.1 - 1.5e-13 50.6 0.1 2.2e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Herpes_IE1 PF07340.11 OEU21746.1 - 0.087 11.7 1.4 0.12 11.3 1.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Biotin_carb_C PF02785.19 OEU21747.1 - 0.071 13.2 0.2 0.67 10.1 0.0 2.4 2 1 1 3 3 3 0 Biotin carboxylase C-terminal domain Med7 PF05983.11 OEU21747.1 - 6 6.9 9.3 9 6.3 4.5 3.0 3 0 0 3 3 3 0 MED7 protein Tim54 PF11711.8 OEU21747.1 - 7.9 5.2 8.8 19 3.9 5.8 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Rieske PF00355.26 OEU21748.1 - 1.1e-17 63.8 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OEU21748.1 - 0.031 14.2 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain DUF1499 PF07386.11 OEU21749.1 - 0.00023 21.7 0.1 0.00042 20.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Sulfatase PF00884.23 OEU21750.1 - 1.7e-45 155.7 0.2 2.5e-45 155.2 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU21750.1 - 0.0069 16.0 0.4 0.094 12.3 0.0 2.4 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OEU21750.1 - 0.054 12.1 0.9 0.13 10.8 0.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF229) ADH_zinc_N_2 PF13602.6 OEU21752.1 - 2.7e-10 41.4 0.0 4.7e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase A_deaminase PF00962.22 OEU21753.1 - 6.1e-65 219.7 0.0 8.3e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Nop PF01798.18 OEU21755.1 - 2.1e-86 289.1 0.1 2.1e-86 289.1 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin CDC45 PF02724.14 OEU21755.1 - 2.4 6.3 25.4 3 6.0 25.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 OEU21755.1 - 5.4 5.9 13.3 8.2 5.3 13.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) WD40 PF00400.32 OEU21756.1 - 2.2e-15 56.8 8.3 0.00011 22.9 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU21756.1 - 1.8e-12 47.4 0.2 0.19 12.0 0.0 5.6 5 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 OEU21756.1 - 0.00056 19.8 0.1 0.0031 17.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 OEU21756.1 - 0.00089 18.3 0.1 1.8 7.4 0.0 3.0 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WLM PF08325.10 OEU21757.1 - 4.4e-25 88.9 0.5 4.7e-25 88.8 0.5 1.0 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 OEU21757.1 - 6.8e-06 26.3 0.3 8.8e-06 25.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 OEU21757.1 - 0.02 14.7 0.4 0.033 14.0 0.4 1.5 1 1 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.6 OEU21757.1 - 0.067 13.3 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12 SUIM_assoc PF16619.5 OEU21758.1 - 0.0068 16.4 3.0 0.0068 16.4 3.0 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TraG_N PF07916.11 OEU21758.1 - 1.7 7.4 5.9 2.2 7.0 5.9 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region ArfGap PF01412.18 OEU21759.1 - 2e-33 114.9 4.3 4.2e-33 113.9 4.3 1.6 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf Amino_oxidase PF01593.24 OEU21760.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU21760.1 - 2.6e-07 30.8 0.0 5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU21760.1 - 0.0012 18.2 0.3 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OEU21760.1 - 0.085 11.7 0.1 0.2 10.5 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase TFIIA PF03153.13 OEU21761.1 - 0.61 10.0 12.7 0.8 9.6 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD_binding_4 PF01565.23 OEU21762.1 - 2.7e-12 46.6 3.2 5.3e-12 45.7 3.2 1.5 1 0 0 1 1 1 1 FAD binding domain FXR_C1 PF16096.5 OEU21763.1 - 0.099 12.9 0.8 0.22 11.7 0.8 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Kei1 PF08552.11 OEU21763.1 - 0.32 10.8 0.1 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 GRA6 PF05084.13 OEU21763.1 - 1.8 8.5 8.2 9.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Granule antigen protein (GRA6) UCH PF00443.29 OEU21764.1 - 9.2e-68 228.5 0.0 1.1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU21764.1 - 1e-18 68.0 1.1 1.3e-14 54.6 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Tom6 PF17112.5 OEU21765.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal DUF745 PF05335.13 OEU21769.1 - 0.0059 16.3 1.7 0.074 12.8 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF745) DUF1336 PF07059.12 OEU21770.1 - 4.1e-56 190.6 0.0 4.9e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) 7TM_GPCR_Srw PF10324.9 OEU21771.1 - 0.0026 17.1 2.3 0.089 12.1 0.2 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3169 PF11368.8 OEU21771.1 - 0.046 13.2 3.7 0.065 12.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Collectrin PF16959.5 OEU21771.1 - 0.14 11.9 2.3 0.35 10.6 2.3 1.6 1 0 0 1 1 1 0 Renal amino acid transporter SLC3A2_N PF16028.5 OEU21771.1 - 0.15 11.6 1.0 0.36 10.4 1.0 1.6 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF5058 PF16481.5 OEU21771.1 - 0.16 11.6 3.1 2.2 7.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5058) RCR PF12273.8 OEU21771.1 - 0.2 12.3 0.0 0.43 11.2 0.0 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4446 PF14584.6 OEU21771.1 - 0.2 11.6 1.8 3.8 7.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4834 PF16118.5 OEU21771.1 - 0.22 12.5 0.1 0.22 12.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) GPR_Gpa2_C PF11970.8 OEU21771.1 - 0.4 10.8 4.7 0.26 11.4 0.3 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term RIFIN PF02009.16 OEU21771.1 - 1.7 8.5 6.0 8.1 6.2 1.2 2.3 2 0 0 2 2 2 0 Rifin LRR19-TM PF15176.6 OEU21771.1 - 6.6 6.8 7.7 52 3.9 7.7 2.5 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SET PF00856.28 OEU21772.1 - 1.5e-08 35.2 1.7 2.1e-08 34.7 1.7 1.5 1 1 0 1 1 1 1 SET domain Herpes_UL55 PF04537.12 OEU21772.1 - 0.053 13.5 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL55 protein SET PF00856.28 OEU21774.1 - 1.2e-05 25.7 0.2 5.3e-05 23.7 0.2 2.0 1 1 0 1 1 1 1 SET domain Methyltransf_25 PF13649.6 OEU21774.1 - 0.008 16.9 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2525 PF10733.9 OEU21774.1 - 0.16 12.3 0.1 0.46 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) DDHD PF02862.17 OEU21775.1 - 8.7e-38 130.7 0.0 8.7e-38 130.7 0.0 4.5 3 2 0 3 3 3 1 DDHD domain DUF676 PF05057.14 OEU21775.1 - 0.051 13.1 0.3 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 OEU21775.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Feld-I_B PF09252.10 OEU21776.1 - 0.0046 16.9 3.8 1.1 9.3 0.9 2.4 1 1 1 2 2 2 2 Allergen Fel d I-B chain DUF4035 PF13227.6 OEU21776.1 - 0.014 15.1 0.7 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) Helicase_C PF00271.31 OEU21777.1 - 3.3e-10 40.3 0.1 1.3e-09 38.4 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 OEU21777.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal AAA_14 PF13173.6 OEU21777.1 - 0.08 13.0 0.1 0.71 9.9 0.1 2.7 1 1 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 OEU21780.1 - 0.0031 17.5 5.9 0.0084 16.1 5.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OEU21780.1 - 0.0041 17.1 2.8 0.011 15.7 2.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Metallophos PF00149.28 OEU21781.1 - 1.5e-05 25.6 0.0 0.0013 19.3 0.0 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Solute_trans_a PF03619.16 OEU21782.1 - 1.2e-63 215.2 5.2 1.5e-63 214.8 5.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AI-2E_transport PF01594.16 OEU21782.1 - 0.035 13.3 0.1 0.061 12.5 0.1 1.3 1 0 0 1 1 1 0 AI-2E family transporter DUF2781 PF10914.8 OEU21782.1 - 0.14 12.6 5.0 0.24 11.8 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) zf-MYND PF01753.18 OEU21783.1 - 7.1e-10 38.8 12.3 1.1e-09 38.2 12.3 1.3 1 0 0 1 1 1 1 MYND finger CDC73_N PF16050.5 OEU21783.1 - 0.073 12.4 0.2 3.5 6.9 0.1 2.1 2 0 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal PolC_DP2 PF03833.13 OEU21783.1 - 0.2 9.5 2.6 0.28 9.0 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ank PF00023.30 OEU21784.1 - 0.0058 17.0 0.0 0.024 15.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OEU21784.1 - 0.076 13.6 0.0 7.5 7.2 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) DUF4834 PF16118.5 OEU21785.1 - 0.017 16.1 0.5 0.017 16.1 0.5 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4834) Cadherin_C_2 PF16492.5 OEU21785.1 - 0.06 14.1 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal O-antigen_lig PF13425.6 OEU21785.1 - 0.088 11.6 0.4 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sigma_reg_N PF13800.6 OEU21785.1 - 0.091 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5383 PF17355.2 OEU21785.1 - 0.36 11.2 0.1 0.36 11.2 0.1 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5383) DUF1980 PF09323.10 OEU21785.1 - 0.79 9.6 4.4 1 9.2 3.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Pox_EPC_I2-L1 PF12575.8 OEU21785.1 - 2.4 8.5 4.8 0.34 11.2 0.3 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 LRR_8 PF13855.6 OEU21786.1 - 3.3e-25 87.6 34.1 6.1e-07 29.1 0.0 6.3 4 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OEU21786.1 - 1.1e-19 70.2 40.2 0.00045 20.6 0.9 8.7 6 2 5 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU21786.1 - 4.4e-06 26.5 27.0 25 5.9 0.0 10.9 12 1 0 12 12 12 1 Leucine Rich Repeat LRR_9 PF14580.6 OEU21786.1 - 0.0018 17.8 5.3 0.019 14.5 1.2 3.1 2 1 0 3 3 3 1 Leucine-rich repeat Cwf_Cwc_15 PF04889.12 OEU21787.1 - 0.023 14.4 17.8 0.029 14.1 17.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NFRKB_winged PF14465.6 OEU21787.1 - 1.3 9.3 5.9 2.9 8.1 0.6 2.9 2 1 0 2 2 2 0 NFRKB Winged Helix-like Vfa1 PF08432.10 OEU21787.1 - 1.4 9.2 11.7 2.1 8.7 11.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4612 PF15389.6 OEU21787.1 - 5.5 8.1 18.0 10 7.2 16.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4612) Inositol_P PF00459.25 OEU21788.1 - 2.7e-63 214.1 0.0 3.2e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Lactonase PF10282.9 OEU21789.1 - 1.7e-62 211.7 0.0 1.5e-61 208.6 0.0 1.9 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller adh_short PF00106.25 OEU21790.1 - 1.4e-36 125.8 5.3 3.1e-36 124.7 5.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU21790.1 - 6.8e-28 97.8 2.8 9.7e-28 97.3 2.8 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU21790.1 - 1.4e-09 38.2 1.6 1.3e-08 35.0 1.6 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU21790.1 - 5.4e-06 25.8 0.2 8.2e-06 25.1 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OEU21790.1 - 1.1e-05 25.1 0.7 2.2e-05 24.0 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU21790.1 - 4.3e-05 23.1 0.5 0.00011 21.8 0.5 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OEU21790.1 - 0.0024 17.8 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 OEU21790.1 - 0.034 13.9 0.4 0.049 13.3 0.1 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.15 OEU21790.1 - 0.041 14.0 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SLATT_5 PF18160.1 OEU21792.1 - 0.015 14.6 1.7 0.031 13.6 0.3 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 LRR_4 PF12799.7 OEU21793.1 - 9.2e-07 29.1 20.1 0.0003 21.1 4.5 3.9 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU21793.1 - 1.6e-05 24.5 20.6 0.0003 20.5 0.3 3.7 3 1 0 3 3 3 2 Leucine rich repeat FGF-BP1 PF06473.12 OEU21793.1 - 0.04 13.8 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) V1R PF03402.14 OEU21793.1 - 0.06 13.0 0.4 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R SARAF PF06682.12 OEU21793.1 - 0.27 10.9 8.6 0.46 10.1 8.1 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis LRR_1 PF00560.33 OEU21793.1 - 2.3 9.1 27.7 1.7 9.5 0.3 7.0 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 OEU21793.1 - 5.1 7.4 24.0 4.2 7.7 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat DUF1635 PF07795.11 OEU21793.1 - 5.3 6.8 6.9 0.6 9.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Thioredoxin PF00085.20 OEU21794.1 - 1.1e-19 70.3 0.0 1.6e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU21794.1 - 8.2e-05 22.7 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OEU21794.1 - 0.00019 21.4 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 OEU21794.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 OEU21794.1 - 0.0024 17.6 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 OEU21794.1 - 0.0026 18.2 0.0 0.053 14.0 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OEU21794.1 - 0.0041 17.4 0.0 0.031 14.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 OEU21794.1 - 0.069 13.1 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_M16 PF00675.20 OEU21796.1 - 2.5e-06 27.6 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) EF-hand_5 PF13202.6 OEU21797.1 - 0.004 16.6 0.1 2.5 7.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU21797.1 - 0.085 13.3 0.0 0.43 11.1 0.0 2.2 1 1 0 1 1 1 0 EF-hand domain pair Peptidase_M22 PF00814.25 OEU21797.1 - 0.11 12.2 3.6 0.083 12.6 1.3 1.9 2 0 0 2 2 2 0 Glycoprotease family DUF3626 PF12294.8 OEU21799.1 - 0.0079 15.3 0.3 0.014 14.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) DUF1948 PF09185.10 OEU21799.1 - 0.048 13.5 2.6 0.13 12.1 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) GramPos_pilinD1 PF16555.5 OEU21799.1 - 0.1 12.8 5.9 0.42 10.8 5.9 2.0 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF4611 PF15387.6 OEU21799.1 - 2.8 8.2 23.7 7.6 6.8 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Hydrolase_4 PF12146.8 OEU21800.1 - 1.8e-07 30.7 0.1 4.4e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OEU21800.1 - 6.5e-06 26.0 0.0 5.9e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OEU21800.1 - 0.00034 20.5 0.9 0.00072 19.4 0.4 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 OEU21800.1 - 0.00079 19.2 0.1 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.7 OEU21800.1 - 0.018 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OEU21800.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 OEU21800.1 - 0.04 13.5 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OEU21800.1 - 0.08 13.5 0.0 0.085 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family EF-hand_6 PF13405.6 OEU21801.1 - 1.3e-14 52.7 4.8 3.4e-05 23.4 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OEU21801.1 - 1.8e-14 53.9 6.6 2.8e-11 43.7 1.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU21801.1 - 4.7e-12 44.5 7.3 0.00035 19.9 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OEU21801.1 - 3.2e-07 30.1 10.4 2.6e-05 24.0 2.0 4.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OEU21801.1 - 8.7e-07 29.2 3.1 0.055 13.8 0.1 3.5 2 2 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU21801.1 - 4.9e-06 25.8 2.6 0.019 14.4 0.1 3.1 3 0 0 3 3 3 2 EF hand PHB_acc_N PF07879.11 OEU21801.1 - 0.0018 18.3 1.1 0.095 12.8 0.0 2.9 1 1 1 2 2 2 1 PHB/PHA accumulation regulator DNA-binding domain Rep-A_N PF04057.12 OEU21801.1 - 0.039 14.0 0.3 0.083 12.9 0.3 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain EFhand_Ca_insen PF08726.10 OEU21801.1 - 0.097 12.8 0.6 2.2 8.4 0.0 2.5 2 2 0 2 2 2 0 Ca2+ insensitive EF hand DUF4854 PF16146.5 OEU21801.1 - 0.29 11.5 4.2 0.65 10.4 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) MMADHC PF10229.9 OEU21802.1 - 9.5e-24 84.6 0.0 1.1e-23 84.4 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Sgf11 PF08209.11 OEU21803.1 - 1.8e-12 46.6 1.4 2.7e-12 46.0 1.4 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 OEU21803.1 - 0.033 14.1 0.6 0.067 13.1 0.6 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type LRR_8 PF13855.6 OEU21804.1 - 5.4e-20 70.9 37.4 3.7e-07 29.8 5.2 5.4 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OEU21804.1 - 1.7e-14 53.7 43.7 3.7e-05 24.0 6.9 6.0 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU21804.1 - 7.1e-06 25.9 35.4 3.7 8.5 1.3 8.2 7 1 0 7 7 7 5 Leucine Rich Repeat LRR_9 PF14580.6 OEU21804.1 - 0.00013 21.5 16.9 0.0058 16.2 3.0 3.2 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 OEU21804.1 - 0.0045 16.9 33.7 0.19 11.9 0.2 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_5 PF13306.6 OEU21804.1 - 0.61 10.0 3.4 0.74 9.8 0.4 2.2 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) TLD PF07534.16 OEU21807.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.6 1 1 0 1 1 1 1 TLD H-K_ATPase_N PF09040.11 OEU21807.1 - 0.013 15.9 1.0 0.027 14.9 1.0 1.5 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain DUF1713 PF08213.11 OEU21807.1 - 1.1 9.2 7.2 2.2 8.3 7.2 1.4 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) Snf7 PF03357.21 OEU21809.1 - 4.6e-40 137.0 14.0 5.6e-40 136.7 14.0 1.1 1 0 0 1 1 1 1 Snf7 HBM PF16591.5 OEU21809.1 - 0.11 11.9 6.7 0.11 11.9 0.4 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain Swi5 PF07061.11 OEU21809.1 - 3.1 7.9 7.8 3.9 7.6 1.3 2.6 3 0 0 3 3 3 0 Swi5 MCM PF00493.23 OEU21810.1 - 2.7e-98 327.5 0.0 3.9e-98 327.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OEU21810.1 - 5.4e-33 113.5 0.0 9.5e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OEU21810.1 - 2.1e-23 82.5 0.2 5.8e-23 81.1 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OEU21810.1 - 6.3e-16 58.9 0.2 1.8e-15 57.4 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OEU21810.1 - 1.3e-09 37.8 0.0 2.6e-07 30.3 0.0 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU21810.1 - 4.2e-07 30.0 0.1 2.3e-06 27.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OEU21810.1 - 0.00023 21.0 0.0 0.0037 17.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 OEU21810.1 - 0.0013 18.5 0.6 0.0058 16.4 0.2 2.3 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 OEU21810.1 - 0.014 15.1 0.1 0.2 11.4 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 OEU21810.1 - 0.094 12.4 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OEU21810.1 - 0.097 13.1 0.0 0.36 11.3 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF836 PF05768.14 OEU21810.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) AAA_16 PF13191.6 OEU21810.1 - 0.26 11.7 1.2 0.97 9.8 0.1 2.6 3 1 0 3 3 3 0 AAA ATPase domain EMP70 PF02990.16 OEU21811.1 - 1.4e-169 565.1 16.0 1.7e-169 564.8 16.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sina PF03145.16 OEU21812.1 - 3.6e-09 36.9 1.5 3.6e-09 36.9 1.5 2.0 3 0 0 3 3 2 1 Seven in absentia protein family zf-RING_UBOX PF13445.6 OEU21812.1 - 2.1e-05 24.5 3.6 2.1e-05 24.5 3.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU21812.1 - 3.2e-05 23.7 9.4 9.4e-05 22.2 9.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU21812.1 - 5.6e-05 23.4 9.9 5.6e-05 23.4 9.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OEU21812.1 - 0.00024 20.9 9.9 0.00059 19.6 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OEU21812.1 - 0.00036 20.6 11.2 0.00078 19.6 11.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OEU21812.1 - 0.0036 17.1 12.9 0.0036 17.1 12.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OEU21812.1 - 0.0056 17.3 1.7 0.0056 17.3 1.7 2.4 2 1 0 2 2 1 1 TRAF-type zinc finger zf-RRN7 PF11781.8 OEU21812.1 - 0.034 13.8 0.3 0.034 13.8 0.3 2.7 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_4 PF14570.6 OEU21812.1 - 1 9.2 15.4 2.6 7.9 15.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OEU21812.1 - 5.4 7.0 13.7 11 6.0 13.7 1.6 1 0 0 1 1 1 0 PHD-finger Abhydrolase_6 PF12697.7 OEU21813.1 - 1e-13 52.4 0.3 1.6e-13 51.8 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU21813.1 - 9.7e-13 48.3 4.1 7.3e-12 45.5 2.4 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OEU21813.1 - 3.7e-08 32.9 0.1 7.5e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OEU21813.1 - 0.001 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.13 OEU21813.1 - 0.016 14.9 0.0 3.2 7.4 0.0 2.3 1 1 1 2 2 2 0 Serine hydrolase (FSH1) DUF2974 PF11187.8 OEU21813.1 - 0.025 14.1 0.1 0.18 11.4 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 OEU21813.1 - 0.055 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 OEU21813.1 - 0.085 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 OEU21813.1 - 0.17 12.0 0.2 1.9 8.6 0.2 2.4 2 1 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 OEU21813.1 - 0.29 10.4 1.1 0.78 9.0 0.3 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) IBR PF01485.21 OEU21816.1 - 8.5e-18 64.3 35.9 4.7e-11 42.7 6.1 3.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OEU21816.1 - 4.4e-06 26.4 1.5 4.4e-06 26.4 1.5 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU21816.1 - 2.1e-05 24.3 1.5 2.1e-05 24.3 1.5 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU21816.1 - 4.7e-05 23.3 2.9 4.7e-05 23.3 2.9 4.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OEU21816.1 - 6e-05 23.3 6.5 6e-05 23.3 6.5 4.6 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OEU21816.1 - 0.00074 19.4 5.3 0.00074 19.4 5.3 4.2 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 OEU21816.1 - 0.0063 16.2 4.1 0.0063 16.2 4.1 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 OEU21816.1 - 0.027 14.6 3.7 0.027 14.6 3.7 4.6 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING dCMP_cyt_deam_1 PF00383.23 OEU21816.1 - 0.088 12.7 2.5 0.22 11.4 2.5 1.7 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Med6 PF04934.14 OEU21818.1 - 0.026 14.3 1.1 0.035 13.9 0.9 1.4 1 1 0 1 1 1 0 MED6 mediator sub complex component EXOSC1 PF10447.9 OEU21818.1 - 0.16 12.6 1.3 0.2 12.3 1.3 1.1 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 TPR_12 PF13424.6 OEU21819.1 - 4.2e-23 81.4 0.2 5.5e-13 49.0 0.6 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU21819.1 - 5.9e-17 61.0 0.4 4.2e-11 42.4 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21819.1 - 1.8e-10 40.1 0.8 1.3e-05 24.9 0.0 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21819.1 - 8.6e-10 38.0 0.1 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OEU21819.1 - 2.2e-09 36.7 0.1 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21819.1 - 5.8e-06 26.1 0.2 0.00086 19.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU21819.1 - 6.7e-06 26.5 0.0 0.033 15.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU21819.1 - 2.2e-05 25.0 0.0 7.5e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU21819.1 - 0.0002 21.8 0.0 0.03 14.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU21819.1 - 0.00029 21.3 0.1 0.0028 18.1 0.0 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat PPR PF01535.20 OEU21819.1 - 0.0018 18.4 0.3 0.73 10.2 0.1 2.3 2 0 0 2 2 2 1 PPR repeat TPR_MalT PF17874.1 OEU21819.1 - 0.0031 17.0 0.1 0.0038 16.6 0.1 1.1 1 0 0 1 1 1 1 MalT-like TPR region ANAPC3 PF12895.7 OEU21819.1 - 0.0038 17.4 0.1 0.027 14.7 0.1 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OEU21819.1 - 0.0038 17.5 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU21819.1 - 0.0096 15.6 1.7 4.1 7.2 0.2 3.2 2 1 1 3 3 3 1 TPR repeat RPN6_N PF18055.1 OEU21819.1 - 0.017 15.5 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Fis1_TPR_C PF14853.6 OEU21819.1 - 0.054 13.6 0.1 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 OEU21819.1 - 0.085 12.9 0.2 1.5 8.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF627) PPR_2 PF13041.6 OEU21819.1 - 0.1 12.8 0.1 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family Foie-gras_1 PF11817.8 OEU21819.1 - 0.19 11.3 0.2 1.7 8.2 0.2 1.9 1 1 1 2 2 2 0 Foie gras liver health family 1 DEAD PF00270.29 OEU21820.1 - 1.1e-42 145.8 0.1 1.8e-42 145.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU21820.1 - 4.7e-32 110.6 0.3 6.3e-31 107.0 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU21820.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OEU21820.1 - 0.00027 21.3 0.9 0.0014 19.0 0.9 2.1 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 OEU21820.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 OEU21820.1 - 0.022 14.5 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 OEU21820.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Helicase Pro_isomerase PF00160.21 OEU21821.1 - 2.8e-40 138.2 0.0 3.2e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7tm_3 PF00003.22 OEU21822.1 - 3.3e-16 59.7 7.6 3.3e-16 59.7 7.6 1.3 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2569 PF10754.9 OEU21822.1 - 0.011 16.1 7.9 0.1 13.0 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Spore_YhaL PF14147.6 OEU21822.1 - 0.029 14.0 3.5 9.9 5.9 0.0 3.3 3 0 0 3 3 3 0 Sporulation protein YhaL Rpr2 PF04032.16 OEU21823.1 - 0.059 13.7 0.4 0.078 13.3 0.4 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MCR PF18509.1 OEU21823.1 - 0.097 12.3 0.3 0.19 11.3 0.3 1.5 1 0 0 1 1 1 0 Magnetochrome domain V_ATPase_I PF01496.19 OEU21824.1 - 0.24 9.3 10.9 3.5 5.4 7.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EMC3_TMCO1 PF01956.16 OEU21824.1 - 2.8 7.7 11.7 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SNARE_assoc PF09335.11 OEU21825.1 - 1.9e-19 70.3 2.0 3.9e-19 69.3 2.0 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein IBR PF01485.21 OEU21826.1 - 4.2e-08 33.3 22.0 1.4e-05 25.2 4.1 4.9 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OEU21826.1 - 0.00019 21.2 1.9 0.00019 21.2 1.9 5.3 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU21826.1 - 0.00033 20.9 5.1 0.00033 20.9 5.1 4.8 3 2 3 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU21826.1 - 0.018 14.9 5.4 0.018 14.9 5.4 5.8 3 2 3 6 6 6 0 Zinc finger, C3HC4 type (RING finger) EMC1_C PF07774.13 OEU21827.1 - 4.6e-57 193.1 0.0 7.1e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal NAD_binding_8 PF13450.6 OEU21828.1 - 3.9e-07 30.2 0.0 9.9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU21828.1 - 0.00075 19.2 0.4 0.0014 18.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SUIM_assoc PF16619.5 OEU21828.1 - 0.0028 17.7 0.8 0.0028 17.7 0.8 2.7 4 0 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 NAD_binding_9 PF13454.6 OEU21828.1 - 0.01 15.8 0.2 0.031 14.3 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU21828.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Med3 PF11593.8 OEU21828.1 - 0.016 14.4 1.3 0.016 14.4 1.3 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Amino_oxidase PF01593.24 OEU21828.1 - 0.042 13.1 0.2 0.47 9.7 0.0 2.4 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OEU21828.1 - 0.21 10.6 0.4 0.31 10.0 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain HemY_N PF07219.13 OEU21829.1 - 0.0067 16.6 0.1 0.0067 16.6 0.1 2.0 3 0 0 3 3 3 1 HemY protein N-terminus Cu-oxidase_2 PF07731.14 OEU21830.1 - 2.1e-13 50.2 0.6 2.1e-13 50.2 0.6 2.8 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OEU21830.1 - 3.4e-05 23.8 0.4 0.00011 22.2 0.4 1.8 1 0 0 1 1 1 1 Multicopper oxidase DUF3438 PF11920.8 OEU21830.1 - 0.16 11.2 1.6 0.27 10.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) SNARE_assoc PF09335.11 OEU21831.1 - 6.7e-19 68.5 14.3 6.7e-19 68.5 14.3 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein Phage_holin_2_3 PF16080.5 OEU21831.1 - 0.062 13.1 0.2 0.062 13.1 0.2 3.7 3 1 1 4 4 4 0 Bacteriophage holin family HP1 DUF2929 PF11151.8 OEU21831.1 - 3.2 8.1 18.9 0.58 10.5 2.8 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2929) DUF2207 PF09972.9 OEU21831.1 - 9.6 4.8 11.2 5.4 5.6 4.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Adipogenin PF15202.6 OEU21832.1 - 0.027 14.5 1.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Adipogenin ABC_tran PF00005.27 OEU21833.1 - 1e-30 107.0 0.0 1.8e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OEU21833.1 - 3e-07 30.1 0.7 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU21833.1 - 9.1e-06 26.0 0.0 5.7e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OEU21833.1 - 7e-05 22.8 4.7 0.021 14.7 0.0 2.5 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU21833.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 OEU21833.1 - 0.0016 18.4 0.1 0.69 9.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU21833.1 - 0.0025 18.2 0.0 0.0065 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OEU21833.1 - 0.0031 17.7 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU21833.1 - 0.0086 16.4 0.0 0.39 11.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain cobW PF02492.19 OEU21833.1 - 0.0099 15.5 0.1 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 OEU21833.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 OEU21833.1 - 0.015 15.0 0.1 0.051 13.3 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OEU21833.1 - 0.016 15.6 0.0 0.26 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OEU21833.1 - 0.019 14.2 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 OEU21833.1 - 0.034 14.7 0.1 0.048 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OEU21833.1 - 0.037 14.5 0.1 0.071 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OEU21833.1 - 0.038 14.4 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 OEU21833.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 OEU21833.1 - 0.04 13.2 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Septin SbcCD_C PF13558.6 OEU21833.1 - 0.054 13.7 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PEPCK_ATP PF01293.20 OEU21833.1 - 0.063 11.9 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_30 PF13604.6 OEU21833.1 - 0.079 12.7 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 OEU21833.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_7 PF12775.7 OEU21833.1 - 0.13 11.8 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF463 PF04317.12 OEU21833.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 TauE PF01925.19 OEU21834.1 - 5.4e-05 22.9 0.0 0.00018 21.3 0.0 1.9 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE HupE_UreJ_2 PF13795.6 OEU21834.1 - 0.027 14.1 0.6 0.43 10.2 0.1 2.3 2 0 0 2 2 2 0 HupE / UreJ protein HupE_UreJ PF04955.12 OEU21834.1 - 0.11 11.9 4.1 0.083 12.4 0.7 2.3 2 0 0 2 2 2 0 HupE / UreJ protein DUF3165 PF11364.8 OEU21834.1 - 0.71 10.3 2.2 4.1 7.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3165) Pkinase PF00069.25 OEU21836.1 - 6.3e-64 215.9 0.0 9.9e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21836.1 - 7.5e-33 113.9 0.0 9.7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU21836.1 - 7.6e-06 25.4 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OEU21836.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OEU21836.1 - 0.00038 19.4 0.0 0.00078 18.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 OEU21836.1 - 0.0014 19.3 4.1 0.0053 17.4 4.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF3502 PF12010.8 OEU21836.1 - 0.17 12.6 1.9 0.39 11.4 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) DUF5100 PF17029.5 OEU21837.1 - 0.023 14.5 0.2 0.034 14.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) NAD_binding_10 PF13460.6 OEU21837.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fer4_12 PF13353.6 OEU21838.1 - 8.9e-05 22.8 0.0 0.00045 20.5 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OEU21838.1 - 0.001 19.2 0.0 0.0045 17.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 OEU21838.1 - 0.016 15.6 0.1 0.051 14.0 0.1 1.9 1 1 0 1 1 1 0 Radical SAM superfamily adh_short PF00106.25 OEU21839.1 - 7.5e-15 54.9 2.8 8.2e-08 31.9 0.8 4.5 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OEU21839.1 - 0.0022 17.6 2.5 0.063 12.8 0.1 3.4 3 1 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase VIT1 PF01988.19 OEU21839.1 - 0.03 14.2 1.3 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 VIT family FAD_binding_3 PF01494.19 OEU21841.1 - 6.8e-06 25.6 0.0 0.00035 19.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 OEU21841.1 - 0.0082 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase HTH_38 PF13936.6 OEU21841.1 - 0.032 14.0 0.3 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain LCD1 PF09798.9 OEU21842.1 - 0.0073 14.9 9.7 0.0075 14.9 9.7 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein gp45-slide_C PF09116.10 OEU21842.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal PhnG PF06754.12 OEU21842.1 - 2.1 8.3 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG Presenilin PF01080.17 OEU21842.1 - 5.9 5.5 18.4 1.3 7.7 15.2 1.5 2 0 0 2 2 2 0 Presenilin NTP_transferase PF00483.23 OEU21843.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase IF3_C PF00707.22 OEU21844.1 - 9.5e-30 102.4 0.4 1.6e-29 101.7 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 OEU21844.1 - 1.6e-20 73.1 0.3 2.9e-20 72.3 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 OEU21844.1 - 0.02 14.6 2.3 0.03 14.0 2.3 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Pox_A32 PF04665.12 OEU21844.1 - 0.049 13.1 0.1 0.068 12.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein GST_C_3 PF14497.6 OEU21845.1 - 2e-10 40.7 0.1 2.8e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OEU21845.1 - 0.00037 20.6 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2489 PF10675.9 OEU21845.1 - 0.11 12.4 4.0 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) FAE1_CUT1_RppA PF08392.12 OEU21846.1 - 5.1e-103 344.4 0.0 8e-103 343.7 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 OEU21846.1 - 2.2e-12 47.2 0.0 4.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 OEU21846.1 - 4.1e-11 42.9 0.0 1.5e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 OEU21846.1 - 0.0031 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 OEU21846.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain SpoVAD PF07451.11 OEU21846.1 - 0.33 9.6 0.8 4.4 5.9 0.2 2.2 1 1 1 2 2 2 0 Stage V sporulation protein AD (SpoVAD) KID PF02524.14 OEU21846.1 - 1.1 9.7 2.6 9.6 6.8 0.1 3.2 3 0 0 3 3 3 0 KID repeat FAM176 PF14851.6 OEU21847.1 - 0.11 12.1 8.0 0.25 11.0 8.0 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OEU21847.1 - 0.26 9.5 13.1 0.33 9.2 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OEU21847.1 - 0.37 10.6 13.7 0.55 10.0 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3682 PF12446.8 OEU21847.1 - 0.6 10.6 11.4 1.2 9.6 11.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Spt20 PF12090.8 OEU21847.1 - 0.61 9.6 21.0 0.93 9.1 21.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF3807 PF12720.7 OEU21847.1 - 0.92 9.8 21.6 1.5 9.0 21.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Neur_chan_memb PF02932.16 OEU21847.1 - 0.96 9.5 7.0 1.2 9.1 7.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 OEU21847.1 - 4.2 6.2 16.6 5.6 5.8 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 OEU21847.1 - 5.9 5.6 8.0 7.6 5.2 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 OEU21847.1 - 6 4.9 9.1 7.7 4.5 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Epimerase PF01370.21 OEU21848.1 - 1.7e-12 47.3 1.7 9.7e-10 38.3 0.0 3.0 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU21848.1 - 6.8e-07 29.0 0.3 7.3e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU21848.1 - 0.00039 19.5 0.2 0.015 14.3 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OEU21848.1 - 0.0015 18.4 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OEU21848.1 - 0.003 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OEU21848.1 - 0.0075 15.5 0.2 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 OEU21848.1 - 0.043 13.3 0.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase BetR PF08667.10 OEU21848.1 - 0.15 12.1 0.0 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 BetR domain 2OG-FeII_Oxy PF03171.20 OEU21849.1 - 0.021 15.3 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2220 PF09983.9 OEU21849.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) DnaJ PF00226.31 OEU21850.1 - 0.013 15.6 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 DnaJ domain Homoserine_dh PF00742.19 OEU21851.1 - 1.1e-52 178.4 0.3 1.9e-52 177.7 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OEU21851.1 - 1.2e-14 54.9 0.4 2.4e-14 54.0 0.4 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PI_PP_I PF18363.1 OEU21853.1 - 1.5 9.0 12.7 0.067 13.4 1.3 3.5 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain CLZ PF16526.5 OEU21853.1 - 4.5 7.7 28.5 4.4 7.7 0.0 6.0 5 1 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAD_binding_4 PF01565.23 OEU21854.1 - 5.8e-17 61.7 0.0 1.1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain LRR_8 PF13855.6 OEU21855.1 - 3.6e-28 97.1 41.8 9.4e-09 34.9 0.8 10.2 7 3 0 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OEU21855.1 - 7.4e-25 86.6 64.8 2.5e-06 27.7 0.5 12.6 8 4 2 12 12 12 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU21855.1 - 1.1e-07 31.3 36.9 6.4 7.1 0.5 12.1 11 0 0 11 11 11 7 Leucine Rich repeat LRR_1 PF00560.33 OEU21855.1 - 0.31 11.7 50.1 6.2 7.8 0.1 14.3 15 2 0 15 15 15 0 Leucine Rich Repeat Adaptin_binding PF10199.9 OEU21855.1 - 0.34 11.5 5.7 1.1 9.9 5.7 1.9 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 LRR_6 PF13516.6 OEU21856.1 - 3.3e-07 29.8 0.2 0.0015 18.4 0.0 3.3 4 0 0 4 4 4 2 Leucine Rich repeat DUF2608 PF11019.8 OEU21856.1 - 0.0023 17.5 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) DUF550 PF04447.12 OEU21856.1 - 0.051 13.7 0.2 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF550) Sel1 PF08238.12 OEU21857.1 - 0.00016 22.2 2.9 0.011 16.3 0.0 2.7 3 0 0 3 3 3 2 Sel1 repeat His_Phos_1 PF00300.22 OEU21858.1 - 9.7e-28 97.2 0.0 6.3e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SYCP2_ARLD PF18581.1 OEU21858.1 - 0.081 12.9 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain DUF4620 PF15399.6 OEU21859.1 - 0.036 14.4 1.4 0.065 13.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Folate_carrier PF01770.18 OEU21859.1 - 2.9 6.5 6.7 0.096 11.4 0.4 1.7 2 0 0 2 2 2 0 Reduced folate carrier YABBY PF04690.13 OEU21859.1 - 8.7 6.9 8.1 1.4e+02 3.0 8.1 2.1 1 1 0 1 1 1 0 YABBY protein MORN PF02493.20 OEU21860.1 - 3.6e-51 168.1 69.4 6.4e-08 32.0 1.6 12.7 13 0 0 13 13 13 11 MORN repeat Tudor_2 PF18104.1 OEU21860.1 - 0.096 12.4 8.2 37 4.1 0.0 6.4 7 0 0 7 7 7 0 Jumonji domain-containing protein 2A Tudor domain DUF1115 PF06544.12 OEU21861.1 - 1.3e-38 132.4 0.2 1.3e-38 132.4 0.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 OEU21861.1 - 1.6e-32 113.0 9.9 1.6e-32 113.0 9.9 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) TLP-20 PF06088.11 OEU21861.1 - 0.016 15.1 0.3 0.016 15.1 0.3 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TFB6 PF17110.5 OEU21861.1 - 0.054 13.2 1.7 0.073 12.8 0.3 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Glutaredoxin PF00462.24 OEU21861.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin FAM176 PF14851.6 OEU21861.1 - 0.31 10.7 9.5 0.94 9.1 0.2 2.6 2 1 0 2 2 2 0 FAM176 family EMC3_TMCO1 PF01956.16 OEU21861.1 - 0.98 9.1 3.7 0.46 10.2 0.6 1.9 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like RNA_polI_A34 PF08208.11 OEU21862.1 - 1.4e-13 51.4 23.3 1.4e-13 51.4 23.3 2.7 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 IMUP PF15761.5 OEU21862.1 - 0.038 14.7 2.1 0.038 14.7 2.1 3.4 2 1 1 3 3 3 0 Immortalisation up-regulated protein ATP-synt_B PF00430.18 OEU21862.1 - 2 8.5 11.6 4.5 7.4 11.6 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) FKBP_C PF00254.28 OEU21863.1 - 2.2e-32 111.2 0.0 2.7e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2071 PF09844.9 OEU21864.1 - 9.9e-08 31.9 0.5 1.7e-07 31.1 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (COG2071) MOZART1 PF12554.8 OEU21866.1 - 5.4e-06 26.1 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated TetR_C_16 PF17920.1 OEU21866.1 - 0.11 12.7 0.6 0.17 12.2 0.1 1.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Macoilin PF09726.9 OEU21866.1 - 1.1 7.8 6.8 1.1 7.8 6.8 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OEU21866.1 - 3.2 6.4 4.4 3.8 6.2 4.4 1.1 1 0 0 1 1 1 0 Presenilin TMEM52 PF14979.6 OEU21867.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 DUF4834 PF16118.5 OEU21867.1 - 0.17 12.9 0.7 0.36 11.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Flavodoxin_2 PF02525.17 OEU21868.1 - 8.7e-26 90.9 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OEU21868.1 - 1e-14 54.6 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DnaJ PF00226.31 OEU21871.1 - 1.9e-21 75.9 0.1 2.2e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OEU21871.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 A repeated domain in UCH-protein DDE_Tnp_1_7 PF13843.6 OEU21872.1 - 0.043 13.1 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 Transposase IS4 Pribosyltran PF00156.27 OEU21873.1 - 8.7e-14 51.3 0.4 1.4e-13 50.6 0.4 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CPT PF07931.12 OEU21873.1 - 0.087 12.7 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FTCD_C PF04961.12 OEU21874.1 - 1e-30 106.9 0.2 1.3e-30 106.6 0.2 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase DUF3793 PF12672.7 OEU21876.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF1844 PF08899.11 OEU21876.1 - 0.17 12.2 0.4 0.39 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) FAD_binding_3 PF01494.19 OEU21877.1 - 1.5e-08 34.3 0.1 1.9e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OEU21877.1 - 4.5e-07 29.4 0.1 1e-06 28.2 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU21877.1 - 3.9e-06 26.2 0.3 5.9e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OEU21877.1 - 6.9e-06 26.2 0.1 1.2e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU21877.1 - 3.3e-05 23.3 0.1 3.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OEU21877.1 - 0.00012 20.9 0.2 0.00019 20.3 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OEU21877.1 - 0.00098 19.6 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU21877.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Glu_dehyd_C PF16912.5 OEU21877.1 - 0.0031 17.0 0.1 0.0065 16.0 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus GIDA PF01134.22 OEU21877.1 - 0.013 14.6 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU21877.1 - 0.037 13.4 0.1 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 OEU21877.1 - 0.04 13.5 0.1 0.047 13.3 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OEU21877.1 - 0.049 14.1 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OEU21877.1 - 0.057 12.5 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 OEU21877.1 - 0.11 12.8 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain ADK PF00406.22 OEU21879.1 - 1.4e-10 41.4 0.0 1.9e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OEU21879.1 - 0.00083 19.8 0.2 0.0027 18.2 0.0 2.0 2 1 1 3 3 3 1 AAA domain ADK_lid PF05191.14 OEU21879.1 - 0.0021 18.0 0.4 0.0059 16.6 0.4 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OEU21879.1 - 0.0034 17.9 0.1 0.02 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 OEU21879.1 - 0.025 15.0 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU21879.1 - 0.041 13.9 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 OEU21879.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase NIF PF03031.18 OEU21880.1 - 0.066 13.0 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase adh_short PF00106.25 OEU21881.1 - 2.8e-31 108.5 0.0 3.2e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU21881.1 - 1.9e-17 63.6 0.0 2.2e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU21881.1 - 0.0018 18.3 0.0 0.0036 17.2 0.0 1.5 1 1 0 1 1 1 1 KR domain TehB PF03848.14 OEU21881.1 - 0.022 14.2 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pax7 PF12360.8 OEU21881.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Paired box protein 7 Methyltransf_11 PF08241.12 OEU21882.1 - 4.2e-07 30.5 0.0 1.4e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU21882.1 - 4.8e-06 26.5 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU21882.1 - 5.1e-05 23.9 0.0 0.00023 21.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 OEU21882.1 - 0.056 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 OEU21882.1 - 0.15 12.8 0.2 0.88 10.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain SAWADEE PF16719.5 OEU21882.1 - 0.48 10.4 2.5 31 4.6 0.0 3.1 3 0 0 3 3 3 0 SAWADEE domain PT PF04886.12 OEU21883.1 - 3.6e-38 128.8 187.8 2.4e-06 27.0 17.0 13.3 4 1 9 13 13 13 9 PT repeat CtaG_Cox11 PF04442.14 OEU21883.1 - 0.0077 16.3 2.8 7.8 6.5 0.4 3.1 1 1 2 3 3 3 3 Cytochrome c oxidase assembly protein CtaG/Cox11 3-dmu-9_3-mt PF06983.13 OEU21883.1 - 0.088 13.3 0.0 98 3.5 0.0 3.1 3 0 0 3 3 3 0 3-demethylubiquinone-9 3-methyltransferase C_tripleX PF02363.19 OEU21883.1 - 3 8.3 10.6 53 4.4 0.3 4.1 3 0 0 3 3 3 0 Cysteine rich repeat NFACT-C PF11923.8 OEU21883.1 - 3.1 7.8 7.7 43 4.1 0.2 3.3 3 0 0 3 3 3 0 NFACT protein C-terminal domain SET PF00856.28 OEU21884.1 - 1.1e-12 48.7 0.1 5.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 SET domain CK2S PF15011.6 OEU21885.1 - 0.11 12.4 12.9 1.8 8.5 3.2 2.8 2 1 0 2 2 2 0 Casein Kinase 2 substrate Anticodon_1 PF08264.13 OEU21887.1 - 0.073 13.0 3.1 3.4 7.6 0.3 2.4 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Cu2_monoox_C PF03712.15 OEU21888.1 - 1.6e-18 66.7 0.0 3.1e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Acyl_transf_3 PF01757.22 OEU21888.1 - 1.2e-15 57.4 27.4 1.2e-15 57.4 27.4 1.7 1 1 0 1 1 1 1 Acyltransferase family Cu2_monooxygen PF01082.20 OEU21888.1 - 3.9e-07 30.4 0.4 9.3e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Acyltransferase PF01553.21 OEU21889.1 - 0.11 12.1 0.2 0.38 10.4 0.0 1.9 1 1 1 2 2 2 0 Acyltransferase PPARgamma_N PF12577.8 OEU21890.1 - 0.83 10.3 11.1 5.2 7.8 0.3 5.8 4 1 0 5 5 5 0 PPAR gamma N-terminal region GSDH PF07995.11 OEU21892.1 - 7.1e-38 130.7 0.0 1.2e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 OEU21892.1 - 1.5e-10 40.7 1.4 3.7e-10 39.5 1.4 1.7 1 0 0 1 1 1 1 PKD domain PT PF04886.12 OEU21892.1 - 0.0003 20.2 5.9 0.00066 19.2 5.9 1.6 1 0 0 1 1 1 1 PT repeat PKD_2 PF16407.5 OEU21892.1 - 0.0026 18.0 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 PKD-like family Big_7 PF17957.1 OEU21892.1 - 0.019 15.7 0.7 0.39 11.5 0.0 3.1 2 1 0 2 2 2 0 Bacterial Ig domain PEGA PF08308.11 OEU21892.1 - 0.1 12.5 0.2 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 PEGA domain FAD_binding_3 PF01494.19 OEU21893.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 OEU21893.1 - 0.15 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Fer4_13 PF13370.6 OEU21894.1 - 2.7e-18 66.3 1.0 6.7e-18 65.0 1.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OEU21894.1 - 5.5e-07 30.2 0.1 1.1e-06 29.3 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain RalF_SCD PF18248.1 OEU21894.1 - 0.0093 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 RalF C-terminal Sec-7 capping domain Fer4_10 PF13237.6 OEU21894.1 - 0.18 11.9 1.1 0.66 10.1 1.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 OEU21894.1 - 0.27 11.1 3.4 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4776 PF16003.5 OEU21895.1 - 0.0021 17.1 0.5 0.0032 16.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) DUF4407 PF14362.6 OEU21895.1 - 0.11 11.9 0.3 0.23 10.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NST1 PF13945.6 OEU21896.1 - 3.4 7.7 17.8 3.6 7.6 16.6 1.6 1 1 1 2 2 2 0 Salt tolerance down-regulator ETRAMP PF09716.10 OEU21896.1 - 8.8 6.5 10.2 13 6.0 0.0 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PCIF1_WW PF12237.8 OEU21897.1 - 6.9e-45 152.7 0.0 8e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain DUF4116 PF13475.6 OEU21898.1 - 3.8e-15 55.4 3.6 0.0041 16.8 0.0 6.4 3 2 4 7 7 7 7 Domain of unknown function (DUF4116) TctB PF07331.11 OEU21899.1 - 0.012 15.8 0.1 0.021 15.1 0.1 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family MatE PF01554.18 OEU21900.1 - 1.1e-34 119.4 21.7 3.6e-24 85.2 8.7 2.7 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OEU21900.1 - 1.3e-09 38.2 5.4 1.3e-09 38.2 5.4 4.3 5 1 1 6 6 6 2 Polysaccharide biosynthesis C-terminal domain MASE4 PF17158.4 OEU21900.1 - 0.0014 17.9 0.7 0.0014 17.9 0.7 2.1 2 0 0 2 2 2 1 Membrane-associated sensor, integral membrane domain polyprenyl_synt PF00348.17 OEU21901.1 - 2.2e-75 253.0 0.6 2.6e-75 252.8 0.6 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF693 PF05113.13 OEU21901.1 - 0.015 14.5 0.8 0.024 13.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Piwi PF02171.17 OEU21902.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Piwi domain SASA PF03629.18 OEU21903.1 - 5.4e-18 65.5 0.0 1.1e-12 48.1 0.0 3.1 3 0 0 3 3 3 3 Carbohydrate esterase, sialic acid-specific acetylesterase TraD PF06412.11 OEU21903.1 - 0.42 10.5 1.9 7.5 6.5 2.2 2.4 2 0 0 2 2 2 0 Conjugal transfer protein TraD SET PF00856.28 OEU21904.1 - 1.3e-10 41.9 0.3 4.4e-10 40.2 0.3 1.7 1 1 0 1 1 1 1 SET domain SAF PF08666.12 OEU21904.1 - 0.034 14.8 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 SAF domain Glyco_hydro_20 PF00728.22 OEU21905.1 - 3.8e-11 43.0 0.2 5.2e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain SusD_RagB PF07980.11 OEU21905.1 - 0.016 14.9 1.6 0.019 14.6 1.6 1.1 1 0 0 1 1 1 0 SusD family Glyco_hydro_20 PF00728.22 OEU21906.1 - 7.5e-46 157.1 0.0 6.2e-39 134.4 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Phage_base_V PF04717.12 OEU21906.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector DUF2236 PF09995.9 OEU21907.1 - 0.019 15.2 0.2 0.02 15.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Herpes_ICP4_N PF03584.15 OEU21907.1 - 0.085 12.7 0.1 0.4 10.5 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region DAGAT PF03982.13 OEU21908.1 - 1.9e-43 148.5 0.0 3.4e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 OEU21908.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 OEU21909.1 - 2.2e-58 197.7 0.0 2.5e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21909.1 - 4.6e-28 98.2 0.0 5.8e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU21909.1 - 9.6e-05 22.4 0.0 0.23 11.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OEU21909.1 - 0.00021 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OEU21909.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OEU21909.1 - 0.00084 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TIR_2 PF13676.6 OEU21909.1 - 0.11 13.1 0.0 0.61 10.7 0.0 2.2 3 0 0 3 3 3 0 TIR domain Tab2_like PF06485.11 OEU21910.1 - 2.7e-76 256.6 0.0 3.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 Nop PF01798.18 OEU21911.1 - 6.1e-84 281.1 0.5 6.1e-84 281.1 0.5 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OEU21911.1 - 1.7e-19 70.0 1.0 1.7e-19 70.0 1.0 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Med19 PF10278.9 OEU21911.1 - 2.5 8.0 33.6 6.7 6.6 30.4 2.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 tRNA_int_end_N2 PF12928.7 OEU21912.1 - 0.003 17.7 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term RNA_replicase_B PF03431.13 OEU21912.1 - 0.008 14.7 1.7 0.012 14.1 1.7 1.2 1 0 0 1 1 1 1 RNA replicase, beta-chain SID-1_RNA_chan PF13965.6 OEU21912.1 - 0.24 9.8 2.1 0.37 9.2 2.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 OEU21912.1 - 0.42 10.6 3.6 0.61 10.1 3.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 OEU21912.1 - 0.79 10.1 5.3 0.27 11.6 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) V_ATPase_I PF01496.19 OEU21912.1 - 1.8 6.4 8.1 2.6 5.9 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 OEU21912.1 - 1.9 7.4 6.1 3.4 6.6 6.1 1.4 1 0 0 1 1 1 0 CLN3 protein Ndc1_Nup PF09531.10 OEU21912.1 - 2.3 6.8 4.6 3.4 6.2 4.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Connexin PF00029.19 OEU21912.1 - 7.1 6.3 8.0 13 5.4 8.0 1.5 1 0 0 1 1 1 0 Connexin Band_3_cyto PF07565.13 OEU21912.1 - 8.5 6.1 10.5 14 5.3 10.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DHODB_Fe-S_bind PF10418.9 OEU21913.1 - 0.045 13.6 2.5 3.8 7.4 0.8 2.5 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Pro_isomerase PF00160.21 OEU21914.1 - 5.6e-15 56.0 0.0 9.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0242 PF06785.11 OEU21914.1 - 0.0038 17.4 7.2 0.006 16.7 7.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TSGA13 PF14994.6 OEU21914.1 - 0.011 15.2 2.5 0.016 14.6 2.5 1.2 1 0 0 1 1 1 0 Testis-specific gene 13 protein PRIMA1 PF16101.5 OEU21914.1 - 0.15 12.1 6.0 0.27 11.3 4.7 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 APG6_N PF17675.1 OEU21914.1 - 4.2 7.9 11.4 6.8 7.2 11.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region adh_short PF00106.25 OEU21915.1 - 3.4e-09 36.5 0.0 9.7e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OEU21915.1 - 6.7e-06 26.1 0.3 1.2e-05 25.3 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OEU21915.1 - 0.00053 19.6 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UPRTase PF14681.6 OEU21918.1 - 2.7e-64 216.4 0.0 3.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OEU21918.1 - 0.00051 19.6 0.0 0.0019 17.7 0.0 1.9 1 1 1 2 2 2 1 Phosphoribosyl transferase domain Hydrolase_4 PF12146.8 OEU21919.1 - 2e-19 69.8 0.0 2.9e-18 66.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU21919.1 - 1.4e-15 58.5 1.0 1.7e-15 58.2 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OEU21919.1 - 5.5e-12 45.9 0.0 4.2e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OEU21919.1 - 3e-08 33.4 0.0 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OEU21919.1 - 4.2e-05 23.5 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 OEU21919.1 - 0.00051 20.2 0.0 0.0036 17.4 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 OEU21919.1 - 0.00083 19.0 0.0 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 OEU21919.1 - 0.0054 16.4 0.0 0.11 12.2 0.0 2.6 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_8 PF06259.12 OEU21919.1 - 0.028 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 OEU21919.1 - 0.047 13.2 0.0 0.097 12.2 0.0 1.6 1 1 1 2 2 2 0 Putative serine esterase (DUF676) TSNAXIP1_N PF15739.5 OEU21919.1 - 0.059 13.8 0.0 3.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Esterase PF00756.20 OEU21919.1 - 0.074 12.7 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Palm_thioest PF02089.15 OEU21919.1 - 0.085 12.7 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Put_DNA-bind_N PF06971.13 OEU21920.1 - 0.14 12.2 0.3 0.4 10.7 0.3 1.8 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus CDC50 PF03381.15 OEU21922.1 - 1.7e-70 237.7 5.5 2.2e-70 237.4 5.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PAN_3 PF08277.12 OEU21922.1 - 9.1 6.2 12.3 1.2 9.0 8.0 1.8 2 0 0 2 2 2 0 PAN-like domain MS_channel PF00924.18 OEU21923.1 - 2.2e-11 43.7 0.1 3.9e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF4945 PF16303.5 OEU21924.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) MutS_IV PF05190.18 OEU21924.1 - 0.095 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV MS_channel PF00924.18 OEU21925.1 - 9.2e-06 25.3 1.0 2.1e-05 24.2 1.0 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2207 PF09972.9 OEU21925.1 - 0.029 13.1 0.1 0.059 12.1 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Totivirus_coat PF05518.11 OEU21925.1 - 1.5 6.8 4.3 2.3 6.1 4.3 1.2 1 0 0 1 1 1 0 Totivirus coat protein MTTB PF06253.11 OEU21926.1 - 0.38 8.7 0.5 0.52 8.2 0.5 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Acetyltransf_10 PF13673.7 OEU21927.1 - 1.8e-11 44.0 1.4 4.1e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OEU21927.1 - 1e-09 38.7 0.0 1.6e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU21927.1 - 1.2e-09 38.4 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU21927.1 - 0.00023 21.1 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OEU21927.1 - 0.004 17.3 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OEU21927.1 - 0.013 15.6 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OEU21927.1 - 0.05 13.1 0.1 0.15 11.5 0.0 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 OEU21927.1 - 0.11 12.6 1.8 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain IF3_N PF05198.16 OEU21927.1 - 0.14 12.4 0.5 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain PP2C PF00481.21 OEU21928.1 - 4.1e-54 183.9 0.0 1.6e-53 182.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OEU21928.1 - 8.1e-06 25.6 0.0 1.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU21928.1 - 0.0038 17.2 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Lipoprotein_15 PF03640.15 OEU21930.1 - 0.022 14.3 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function GST_C_3 PF14497.6 OEU21931.1 - 2.1e-06 27.9 0.0 6e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CRA PF06589.11 OEU21933.1 - 0.0013 18.9 0.2 0.0024 18.0 0.2 1.4 1 0 0 1 1 1 1 Circumsporozoite-related antigen (CRA) PAC1 PF16094.5 OEU21933.1 - 0.013 14.7 0.3 0.017 14.3 0.3 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DUF2151 PF10221.9 OEU21933.1 - 0.078 11.6 0.2 0.09 11.4 0.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ubiquitin PF00240.23 OEU21934.1 - 5.6e-13 48.4 0.2 1.9e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DDE_Tnp_4 PF13359.6 OEU21934.1 - 7.1e-08 32.3 0.1 3e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease ACAS_N PF16177.5 OEU21934.1 - 0.00011 22.1 1.1 0.0004 20.2 0.2 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Rad60-SLD PF11976.8 OEU21934.1 - 0.0007 19.4 1.8 0.0016 18.3 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-MYND PF01753.18 OEU21935.1 - 3.1e-10 40.0 14.5 5.2e-10 39.3 14.5 1.4 1 0 0 1 1 1 1 MYND finger ERM PF00769.19 OEU21935.1 - 0.00071 19.5 12.5 0.00091 19.1 12.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fmp27_WPPW PF10359.9 OEU21935.1 - 0.0051 15.7 3.6 0.0055 15.6 3.6 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.19 OEU21935.1 - 0.0054 14.7 5.6 0.0061 14.6 5.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GrpE PF01025.19 OEU21935.1 - 0.071 12.8 12.0 0.12 12.1 12.0 1.3 1 0 0 1 1 1 0 GrpE DUF4795 PF16043.5 OEU21935.1 - 0.079 12.6 20.5 0.14 11.7 20.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF244 PF03112.14 OEU21935.1 - 0.11 12.4 2.7 0.16 11.8 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF XPG_I_2 PF12813.7 OEU21935.1 - 0.27 10.7 4.9 0.46 9.9 4.9 1.3 1 0 0 1 1 1 0 XPG domain containing FapA PF03961.13 OEU21935.1 - 0.7 8.4 13.5 0.96 8.0 13.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A T2SSF PF00482.23 OEU21935.1 - 0.85 9.6 3.4 1.3 9.0 3.4 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F MCM3AP_GANP PF16769.5 OEU21935.1 - 1.1 7.4 10.4 1.4 7.1 10.4 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF4145 PF13643.6 OEU21935.1 - 1.4 9.1 6.7 0.5 10.5 2.8 2.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4145) YkuI_C PF10388.9 OEU21935.1 - 2.4 7.9 10.9 4.2 7.1 10.9 1.4 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Nup54 PF13874.6 OEU21935.1 - 3.7 7.7 13.7 6.2 6.9 13.7 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3584 PF12128.8 OEU21935.1 - 4.8 4.6 16.6 6.1 4.2 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-Mss51 PF13824.6 OEU21935.1 - 7.4 6.8 10.7 68 3.7 10.9 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 MCU PF04678.13 OEU21935.1 - 7.8 6.6 14.1 2.1 8.4 10.7 1.8 1 1 1 2 2 2 0 Mitochondrial calcium uniporter MgtE_N PF03448.17 OEU21937.1 - 0.46 11.1 3.2 2 9.1 0.2 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain DnaJ PF00226.31 OEU21938.1 - 7.5e-23 80.4 1.8 8.2e-23 80.3 1.8 1.0 1 0 0 1 1 1 1 DnaJ domain Peptidase_C48 PF02902.19 OEU21939.1 - 4.2e-26 92.1 5.3 4.9e-26 91.9 5.3 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.29 OEU21940.1 - 0.25 11.3 4.5 0.55 10.2 4.5 1.6 1 0 0 1 1 1 0 PHD-finger DUF3050 PF11251.8 OEU21942.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) IBR PF01485.21 OEU21943.1 - 7.8e-12 45.2 16.3 2.4e-09 37.3 7.3 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Orf78 PF06024.12 OEU21945.1 - 0.4 11.0 1.5 1.4 9.3 0.1 2.6 3 0 0 3 3 3 0 Orf78 (ac78) Thioredoxin PF00085.20 OEU21946.1 - 9.7e-08 31.9 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 OEU21946.1 - 0.017 15.5 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 OEU21946.1 - 0.019 14.3 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family MatE PF01554.18 OEU21948.1 - 1.8e-31 109.0 27.2 1.8e-17 63.5 6.2 2.8 3 0 0 3 3 3 2 MatE RelA_SpoT PF04607.17 OEU21949.1 - 6.3e-26 91.0 0.3 1.6e-25 89.7 0.3 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 OEU21949.1 - 0.012 15.3 0.0 0.13 12.0 0.0 2.3 1 1 0 1 1 1 0 HD domain HHH_6 PF14579.6 OEU21949.1 - 0.015 15.5 0.1 2.4 8.5 0.0 2.6 2 1 1 3 3 3 0 Helix-hairpin-helix motif QIL1 PF15884.5 OEU21949.1 - 0.052 14.1 0.2 0.18 12.4 0.1 1.9 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 2OG-FeII_Oxy_2 PF13532.6 OEU21950.1 - 2.5e-05 24.6 0.0 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TTL PF03133.15 OEU21951.1 - 3.8e-16 59.1 0.2 6.6e-15 55.0 0.0 2.5 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OEU21951.1 - 0.00066 19.0 0.0 0.0048 16.2 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp PseudoU_synth_1 PF01416.20 OEU21952.1 - 2.1e-10 41.0 0.0 7.2e-05 23.2 0.0 3.0 2 2 0 2 2 2 2 tRNA pseudouridine synthase Allexi_40kDa PF05549.11 OEU21952.1 - 0.2 11.2 4.2 2 7.9 0.1 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein GNAT_acetyltr_2 PF13718.6 OEU21952.1 - 0.85 9.0 4.1 0.82 9.0 0.1 2.4 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF1995 PF09353.10 OEU21953.1 - 3.7e-34 118.5 0.0 9.3e-34 117.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) Homoserine_dh PF00742.19 OEU21954.1 - 5.7e-42 143.6 0.1 1.5e-41 142.2 0.1 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.28 OEU21954.1 - 1.1e-33 116.8 0.1 1.1e-31 110.3 0.0 3.1 2 1 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.16 OEU21954.1 - 8.9e-16 58.6 0.0 2.7e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 OEU21954.1 - 1.4e-10 40.8 3.2 8.9e-05 22.2 0.2 3.0 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 OEU21954.1 - 1.5e-06 27.9 0.8 0.066 13.0 0.1 2.8 2 0 0 2 2 2 2 ACT domain Semialdhyde_dh PF01118.24 OEU21954.1 - 0.0044 17.4 0.1 0.13 12.7 0.1 2.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OEU21954.1 - 0.04 14.1 0.0 0.21 11.7 0.0 2.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PseudoU_synth_2 PF00849.22 OEU21955.1 - 3.6e-14 53.2 5.1 7.6e-12 45.6 5.1 3.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase Ocnus PF05005.15 OEU21955.1 - 1.3e-12 47.8 0.2 1e-11 44.9 0.2 2.4 1 1 0 1 1 1 1 Janus/Ocnus family (Ocnus) BIRC6 PF12356.8 OEU21955.1 - 0.046 13.2 0.2 1 8.8 0.0 2.8 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 SUIM_assoc PF16619.5 OEU21955.1 - 6.8 6.8 10.4 8.9 6.5 8.5 2.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hist_deacetyl PF00850.19 OEU21956.1 - 1.3e-47 162.8 0.2 7.2e-47 160.3 0.2 1.8 1 1 0 1 1 1 1 Histone deacetylase domain MRP-L47 PF06984.13 OEU21957.1 - 8.9e-27 93.0 0.8 9.8e-27 92.9 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 OEU21957.1 - 7.5e-05 22.6 0.6 8.9e-05 22.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein TPMT PF05724.11 OEU21958.1 - 6.3e-27 94.7 0.0 6.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OEU21958.1 - 1.5e-08 35.2 0.0 2.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU21958.1 - 4.8e-07 30.3 0.0 7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU21958.1 - 6.3e-07 30.1 0.0 1e-06 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OEU21958.1 - 0.038 13.6 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OEU21958.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3801 PF12687.7 OEU21960.1 - 0.00012 22.2 1.2 0.00021 21.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) DUF2722 PF10846.8 OEU21960.1 - 0.0014 17.6 15.3 0.0023 17.0 15.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF3292 PF11696.8 OEU21960.1 - 0.14 10.5 5.7 0.077 11.4 3.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) EPL1 PF10513.9 OEU21960.1 - 0.31 11.4 10.2 0.11 12.8 7.8 1.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Presenilin PF01080.17 OEU21960.1 - 0.34 9.6 6.4 0.45 9.2 6.4 1.2 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 OEU21960.1 - 0.37 10.1 10.7 0.59 9.5 10.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pal1 PF08316.11 OEU21960.1 - 0.44 11.3 3.1 0.32 11.7 0.8 1.9 2 0 0 2 2 2 0 Pal1 cell morphology protein DUF4175 PF13779.6 OEU21960.1 - 1.1 7.1 17.4 1.4 6.7 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PepSY_TM PF03929.16 OEU21960.1 - 1.6 8.3 4.9 2.4 7.8 4.9 1.3 1 0 0 1 1 1 0 PepSY-associated TM region EIIBC-GUT_N PF03612.14 OEU21960.1 - 2.2 8.0 7.0 0.36 10.6 3.3 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TMEM51 PF15345.6 OEU21960.1 - 3.7 7.3 11.0 6.2 6.6 11.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 NUDIX PF00293.28 OEU21961.1 - 3.6e-14 52.9 0.1 5.2e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 OEU21963.1 - 2.6e-12 47.0 0.0 4.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU21963.1 - 4.1e-07 30.3 0.0 5.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU21963.1 - 0.00032 20.6 0.1 0.0022 17.9 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU21963.1 - 0.011 15.7 0.1 0.042 13.8 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 OEU21963.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aminotran_1_2 PF00155.21 OEU21964.1 - 7e-41 140.6 0.0 9.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF484 PF04340.12 OEU21964.1 - 0.15 11.7 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 TFIIA PF03153.13 OEU21970.1 - 0.068 13.2 25.2 0.085 12.8 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PA26 PF04636.13 OEU21970.1 - 0.2 10.5 9.5 0.25 10.2 9.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PPP4R2 PF09184.11 OEU21970.1 - 0.28 10.8 18.3 0.37 10.3 18.3 1.2 1 0 0 1 1 1 0 PPP4R2 CAC1F_C PF16885.5 OEU21970.1 - 1.4 8.5 16.2 1.8 8.1 16.2 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Ndc1_Nup PF09531.10 OEU21970.1 - 1.6 7.3 15.9 2.3 6.8 15.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CSG2 PF16965.5 OEU21970.1 - 3.2 6.6 7.0 4.2 6.2 7.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Dicty_REP PF05086.12 OEU21970.1 - 3.2 5.6 18.6 4.1 5.3 18.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PhyH PF05721.13 OEU21972.1 - 6.5e-12 46.2 0.0 1.1e-11 45.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4834 PF16118.5 OEU21973.1 - 1.5 9.8 6.0 0.66 11.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Serinc PF03348.15 OEU21973.1 - 5.6 5.8 5.5 35 3.2 5.0 2.3 2 1 0 2 2 2 0 Serine incorporator (Serinc) Glyco_transf_15 PF01793.16 OEU21974.1 - 0.17 11.1 8.7 3.6 6.7 2.6 2.9 2 2 1 3 3 3 0 Glycolipid 2-alpha-mannosyltransferase Bromo_TP PF07524.13 OEU21975.1 - 0.00059 19.8 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated SUIM_assoc PF16619.5 OEU21975.1 - 0.0031 17.6 3.9 0.0073 16.4 3.9 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Hydin_ADK PF17213.3 OEU21975.1 - 1.5 9.1 13.9 0.2 11.9 3.9 2.5 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain ATP-gua_Ptrans PF00217.19 OEU21976.1 - 2.7e-45 154.4 0.0 1.4e-43 148.9 0.0 2.1 1 1 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OEU21976.1 - 2.5e-23 82.2 0.0 6.2e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain NTF2 PF02136.20 OEU21978.1 - 1.3e-20 74.1 0.0 1.5e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 OEU21978.1 - 0.099 13.3 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Fibrillarin PF01269.17 OEU21979.1 - 1.3e-92 309.0 0.0 1.6e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OEU21979.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OEU21979.1 - 0.035 13.8 0.0 0.073 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3237 PF11578.8 OEU21979.1 - 0.068 13.0 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) Methyltr_RsmB-F PF01189.17 OEU21979.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PPR_2 PF13041.6 OEU21980.1 - 2.9e-41 139.4 11.9 3.3e-11 43.2 0.1 8.9 5 3 3 8 8 8 8 PPR repeat family PPR_1 PF12854.7 OEU21980.1 - 4e-41 138.4 18.9 1.7e-07 30.8 0.0 11.3 11 1 0 11 11 11 8 PPR repeat PPR PF01535.20 OEU21980.1 - 6.9e-32 107.4 28.5 8.8e-06 25.6 0.0 12.2 10 3 0 10 10 10 6 PPR repeat PPR_3 PF13812.6 OEU21980.1 - 2.6e-28 97.9 3.4 4.8e-11 42.6 0.1 7.0 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU21980.1 - 1.4e-09 37.7 2.5 0.00013 21.4 0.2 3.6 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OEU21980.1 - 0.0042 17.6 2.9 0.73 10.4 0.3 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat SPOB_a PF14689.6 OEU21980.1 - 0.19 11.4 1.4 3.6 7.4 0.0 3.7 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain CysG_dimeriser PF10414.9 OEU21980.1 - 0.53 10.0 2.6 3.6 7.4 0.1 3.5 5 0 0 5 5 5 0 Sirohaem synthase dimerisation region Synaptonemal_3 PF15191.6 OEU21980.1 - 0.76 9.6 2.8 4.5 7.1 0.3 2.7 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 PPR_2 PF13041.6 OEU21981.1 - 6.4e-06 26.3 0.6 0.00056 20.0 0.0 3.4 2 1 1 3 3 3 2 PPR repeat family PPR_1 PF12854.7 OEU21981.1 - 2.9e-05 23.7 0.0 0.2 11.4 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 OEU21981.1 - 0.0016 17.9 0.0 0.019 14.4 0.0 2.1 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP DUF2554 PF10829.8 OEU21981.1 - 0.0052 17.2 0.9 2.9 8.4 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2554) PPR PF01535.20 OEU21981.1 - 0.041 14.1 3.4 15 6.1 0.0 4.6 5 2 0 5 5 5 0 PPR repeat Pox_I3 PF04661.12 OEU21981.1 - 0.06 12.5 0.1 0.083 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein YchF-GTPase_C PF06071.13 OEU21981.1 - 0.085 13.1 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF933) PRP38_assoc PF12871.7 OEU21981.1 - 0.53 10.9 4.1 0.92 10.2 4.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TPR_12 PF13424.6 OEU21983.1 - 0.00048 20.4 3.6 0.63 10.4 2.1 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU21983.1 - 0.0044 17.1 2.5 4.7 7.7 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU21983.1 - 0.0062 16.6 0.3 6.3 7.2 0.4 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU21983.1 - 0.47 10.4 7.0 0.73 9.8 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU21983.1 - 0.51 10.3 9.1 24 4.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat O-FucT PF10250.9 OEU21984.1 - 2e-05 24.4 0.0 8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CAP PF00188.26 OEU21985.1 - 0.024 15.5 0.1 0.16 12.8 0.1 2.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family ADH_zinc_N PF00107.26 OEU21986.1 - 2e-22 79.5 0.0 3.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU21986.1 - 6.4e-18 66.1 0.0 1.1e-17 65.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU21986.1 - 2.9e-13 49.6 0.2 8e-12 45.0 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OEU21986.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 OEU21986.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Arm PF00514.23 OEU21988.1 - 0.00011 22.1 0.1 0.65 10.1 0.2 4.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HSF_DNA-bind PF00447.17 OEU21989.1 - 1.6e-12 47.8 0.0 1.8e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Amino_oxidase PF01593.24 OEU21990.1 - 2.2e-66 225.0 0.0 3.5e-66 224.4 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OEU21990.1 - 1.4e-08 34.9 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OEU21990.1 - 0.086 12.1 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0180 PF03698.13 OEU21990.1 - 0.16 12.2 0.0 9.2 6.5 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0180) MRC1 PF09444.10 OEU21991.1 - 0.78 10.2 27.0 1.9 9.0 10.1 2.3 2 0 0 2 2 2 0 MRC1-like domain PI3K_1B_p101 PF10486.9 OEU21991.1 - 3.3 5.4 27.6 6.2 4.5 27.5 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YL1 PF05764.13 OEU21991.1 - 6.6 6.8 55.1 0.16 12.1 22.6 2.3 1 1 1 2 2 2 0 YL1 nuclear protein Maf1 PF09174.10 OEU21992.1 - 3e-28 99.1 22.5 6.7e-26 91.5 22.5 2.5 1 1 0 1 1 1 1 Maf1 regulator NST1 PF13945.6 OEU21992.1 - 2.5 8.2 15.5 2.1 8.4 13.7 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator Presenilin PF01080.17 OEU21992.1 - 6.1 5.5 8.4 8.8 5.0 8.4 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_2 PF13639.6 OEU21993.1 - 4.4e-13 49.3 7.0 5.1e-13 49.1 7.0 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU21993.1 - 1.3e-08 34.4 4.0 2.2e-08 33.7 4.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU21993.1 - 1.6e-08 34.3 6.8 2.6e-08 33.6 6.8 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU21993.1 - 8.5e-08 32.4 10.7 3.7e-07 30.3 10.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OEU21993.1 - 1.9e-07 30.8 3.6 3.3e-07 30.1 3.6 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU21993.1 - 1.1e-06 28.5 3.1 1.7e-06 28.0 3.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OEU21993.1 - 0.00022 21.2 5.0 0.00049 20.1 5.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OEU21993.1 - 0.00033 20.8 7.9 0.0012 18.9 7.9 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 OEU21993.1 - 0.0024 17.8 4.4 0.0052 16.7 4.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU21993.1 - 0.004 17.0 6.2 0.0092 15.8 6.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OEU21993.1 - 0.0065 16.4 3.3 0.029 14.3 0.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OEU21993.1 - 0.0086 15.8 2.4 0.013 15.2 2.4 1.4 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C2H2_3 PF13878.6 OEU21993.1 - 0.01 15.6 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn_ribbon_17 PF17120.5 OEU21993.1 - 0.016 14.8 6.1 0.028 14.1 6.1 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 OEU21993.1 - 0.026 14.6 1.1 0.034 14.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 OEU21993.1 - 0.027 14.3 3.4 0.039 13.8 3.4 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 OEU21993.1 - 0.12 12.5 3.0 0.15 12.2 3.0 1.3 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING-like PF08746.11 OEU21993.1 - 0.17 12.2 8.5 0.37 11.1 8.5 1.7 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OEU21993.1 - 0.38 11.0 5.6 0.86 9.8 2.5 2.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OEU21993.1 - 0.5 10.5 7.3 1.8 8.8 7.4 1.8 1 1 1 2 2 2 0 RING-variant domain zf-C3H2C3 PF17122.5 OEU21993.1 - 2.2 8.4 10.2 17 5.6 10.2 2.3 1 1 0 1 1 1 0 Zinc-finger Pkinase PF00069.25 OEU21994.1 - 5.9e-46 157.0 0.2 6.7e-45 153.5 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU21994.1 - 2.5e-24 86.0 0.1 6.3e-24 84.7 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OEU21994.1 - 0.00027 19.8 0.8 0.0018 17.1 0.2 2.0 1 1 1 2 2 2 1 Fungal protein kinase DENN PF02141.21 OEU21995.1 - 7e-25 88.1 0.1 1.1e-24 87.4 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Cortexin PF11057.8 OEU21995.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Cortexin of kidney RIFIN PF02009.16 OEU21996.1 - 4.9 7.0 7.4 7.6 6.3 7.4 1.2 1 0 0 1 1 1 0 Rifin Mitofilin PF09731.9 OEU21996.1 - 7.6 5.2 14.9 11 4.7 14.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein VDE PF07137.11 OEU21997.1 - 1.1e-89 300.1 0.1 1.6e-89 299.6 0.1 1.2 1 0 0 1 1 1 1 VDE lipocalin domain DUF1205 PF06722.12 OEU21998.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) MFS_1 PF07690.16 OEU21999.1 - 3.7e-30 105.1 27.8 3.7e-30 105.1 27.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU21999.1 - 2.5e-10 39.8 6.0 2.5e-10 39.8 6.0 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 OEU21999.1 - 0.00023 20.0 4.1 0.00023 20.0 4.1 1.7 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_1_like PF12832.7 OEU21999.1 - 0.019 13.8 0.1 0.019 13.8 0.1 2.8 1 1 1 3 3 3 0 MFS_1 like family Peptidase_S8 PF00082.22 OEU22000.1 - 1.6e-30 106.4 6.7 1.8e-30 106.3 6.7 1.0 1 0 0 1 1 1 1 Subtilase family Hamartin PF04388.12 OEU22001.1 - 7.4 5.1 27.5 10 4.6 27.5 1.1 1 0 0 1 1 1 0 Hamartin protein MGS PF02142.22 OEU22002.1 - 0.03 14.5 0.0 0.086 13.0 0.0 1.8 1 1 0 1 1 1 0 MGS-like domain AMP-binding PF00501.28 OEU22003.1 - 8e-52 176.2 0.0 1.4e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Isochorismatase PF00857.20 OEU22003.1 - 2.1e-29 102.9 0.1 4.3e-29 101.9 0.1 1.5 1 0 0 1 1 1 1 Isochorismatase family FSH1 PF03959.13 OEU22003.1 - 1.6e-21 77.0 0.0 9.2e-21 74.5 0.0 2.2 2 1 0 2 2 2 1 Serine hydrolase (FSH1) AMP-binding_C PF13193.6 OEU22003.1 - 7.9e-06 26.8 0.1 3.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ER_lumen_recept PF00810.18 OEU22003.1 - 1.1 10.0 6.7 0.31 11.8 3.3 1.8 2 0 0 2 2 2 0 ER lumen protein retaining receptor MerC PF03203.14 OEU22003.1 - 1.3 9.5 7.5 11 6.5 2.2 3.2 1 1 1 2 2 2 0 MerC mercury resistance protein PseudoU_synth_2 PF00849.22 OEU22006.1 - 1.6e-14 54.3 0.5 1.3e-13 51.4 0.5 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OEU22006.1 - 5.4e-05 22.8 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain DUF3439 PF11921.8 OEU22006.1 - 2.8 7.9 10.7 5.5 7.0 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RNB PF00773.19 OEU22007.1 - 7.6e-91 304.8 0.0 1e-90 304.4 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OEU22007.1 - 1.2e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 OEU22007.1 - 0.17 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Brix PF04427.18 OEU22008.1 - 2.9e-27 96.0 0.0 4.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain Dus PF01207.17 OEU22009.1 - 1.4e-42 145.9 0.1 9.1e-41 139.9 0.1 2.8 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) PAC3 PF10178.9 OEU22009.1 - 0.045 13.9 0.2 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 ExbD PF02472.16 OEU22009.1 - 0.17 12.0 0.1 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Atx10homo_assoc PF09759.9 OEU22010.1 - 2.7e-06 27.3 2.0 0.00067 19.6 0.1 3.6 2 1 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 OEU22010.1 - 3.2e-05 23.8 7.0 0.22 11.7 0.1 5.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Actin PF00022.19 OEU22011.1 - 5.4e-58 196.5 0.0 5.3e-31 107.6 0.0 2.0 1 1 1 2 2 2 2 Actin PLAC8 PF04749.17 OEU22012.1 - 2.1e-17 63.9 13.7 3.2e-17 63.3 13.7 1.3 1 0 0 1 1 1 1 PLAC8 family DUF4312 PF14189.6 OEU22013.1 - 0.00052 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4312) NIF PF03031.18 OEU22014.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.14 OEU22014.1 - 0.12 12.0 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) MFS_1_like PF12832.7 OEU22015.1 - 2e-50 171.8 23.6 3.1e-50 171.1 23.6 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OEU22015.1 - 1.6e-22 79.9 27.1 1.8e-21 76.5 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PX PF00787.24 OEU22016.1 - 3.2e-13 49.7 0.1 4.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 PX domain TIP49 PF06068.13 OEU22017.1 - 8.4e-139 462.6 1.5 1.9e-138 461.5 1.5 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OEU22017.1 - 1.7e-20 72.9 0.3 4.2e-20 71.7 0.3 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OEU22017.1 - 2.5e-08 34.4 0.3 4e-05 24.1 0.0 3.0 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OEU22017.1 - 1.7e-06 27.9 0.1 0.0052 16.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU22017.1 - 7.9e-05 22.9 0.0 0.084 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OEU22017.1 - 0.0001 22.7 0.0 0.00075 19.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 OEU22017.1 - 0.00022 20.6 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 OEU22017.1 - 0.001 18.5 0.6 0.084 12.2 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OEU22017.1 - 0.0031 17.5 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OEU22017.1 - 0.0036 17.1 0.1 0.0065 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 OEU22017.1 - 0.022 13.9 0.0 0.087 11.9 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OEU22017.1 - 0.024 14.2 0.1 0.057 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU22017.1 - 0.026 15.1 0.0 0.081 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 OEU22017.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OEU22017.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU22017.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OEU22017.1 - 0.18 11.3 0.3 1.5 8.3 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region bZIP_2 PF07716.15 OEU22018.1 - 6.1e-07 29.4 1.2 6.1e-07 29.4 1.2 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OEU22018.1 - 4e-05 23.6 0.5 0.0001 22.3 0.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Esterase PF00756.20 OEU22018.1 - 0.029 14.0 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Putative esterase FKBP_C PF00254.28 OEU22020.1 - 1e-07 32.2 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PAS_9 PF13426.7 OEU22021.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OEU22021.1 - 0.0018 18.3 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OEU22021.1 - 0.044 14.0 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 PAS fold TLP-20 PF06088.11 OEU22021.1 - 0.32 10.9 3.0 0.54 10.1 3.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) UQ_con PF00179.26 OEU22022.1 - 5.2e-52 175.2 0.0 5.9e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OEU22022.1 - 0.023 15.0 0.1 0.034 14.4 0.1 1.4 1 1 0 1 1 1 0 RWD domain Ribosomal_L7Ae PF01248.26 OEU22023.1 - 0.001 18.8 0.1 0.0037 17.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4808 PF16066.5 OEU22023.1 - 6.5 7.3 10.8 0.89 10.1 1.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4808) Thioredoxin PF00085.20 OEU22024.1 - 7.2e-15 54.8 0.0 8.7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OEU22024.1 - 9.7e-06 25.1 0.2 1.4e-05 24.6 0.2 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OEU22024.1 - 0.0056 17.1 0.0 0.0086 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OEU22024.1 - 0.017 14.9 0.0 0.056 13.3 0.0 1.8 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 OEU22024.1 - 0.046 13.9 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 OEU22024.1 - 0.15 12.4 0.0 4.6 7.6 0.0 2.5 2 1 1 3 3 3 0 Thioredoxin-like AAA PF00004.29 OEU22025.1 - 7.6e-45 152.6 0.4 4.1e-44 150.2 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OEU22025.1 - 1.4e-08 34.9 0.1 4.3e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 OEU22025.1 - 3.1e-08 33.5 0.0 2.3e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OEU22025.1 - 1.1e-07 32.2 0.1 3.6e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 OEU22025.1 - 3.7e-07 29.8 0.0 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OEU22025.1 - 2.4e-06 28.0 0.1 0.0011 19.4 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OEU22025.1 - 0.00015 21.0 0.0 0.00033 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OEU22025.1 - 0.00061 20.3 0.0 0.0029 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OEU22025.1 - 0.00064 19.3 0.1 0.0024 17.4 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 OEU22025.1 - 0.00089 18.6 0.0 0.0055 16.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 OEU22025.1 - 0.0011 18.7 0.0 0.0036 17.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU22025.1 - 0.0014 18.9 4.0 0.064 13.5 0.1 3.0 3 1 1 4 4 3 1 AAA domain Mg_chelatase PF01078.21 OEU22025.1 - 0.0019 17.7 0.2 0.0045 16.4 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OEU22025.1 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_30 PF13604.6 OEU22025.1 - 0.0094 15.7 0.1 0.019 14.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OEU22025.1 - 0.0096 16.2 0.6 0.032 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OEU22025.1 - 0.0098 15.6 0.2 0.023 14.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OEU22025.1 - 0.014 15.2 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OEU22025.1 - 0.014 15.5 0.6 0.09 12.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 OEU22025.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 OEU22025.1 - 0.023 14.6 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 OEU22025.1 - 0.028 13.8 1.9 0.16 11.3 0.0 2.5 3 0 0 3 3 3 0 KaiC DUF3450 PF11932.8 OEU22025.1 - 0.036 13.4 0.6 0.075 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_17 PF13207.6 OEU22025.1 - 0.05 14.0 0.1 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 OEU22025.1 - 0.053 13.2 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OEU22025.1 - 0.053 12.6 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Spc24 PF08286.11 OEU22025.1 - 0.088 13.1 3.4 2.8 8.2 3.1 2.5 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_25 PF13481.6 OEU22025.1 - 0.094 12.3 0.7 0.29 10.7 0.3 1.9 1 1 1 2 2 2 0 AAA domain Prefoldin_2 PF01920.20 OEU22025.1 - 0.12 12.3 4.5 0.078 12.9 2.1 1.9 2 0 0 2 2 2 0 Prefoldin subunit AAA_11 PF13086.6 OEU22025.1 - 0.16 11.8 0.4 0.42 10.3 0.1 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OEU22025.1 - 0.17 11.8 1.2 0.55 10.1 0.2 2.3 3 0 0 3 3 3 0 NACHT domain MA3 PF02847.17 OEU22026.1 - 4.8e-24 84.5 0.1 1.6e-23 82.8 0.1 1.9 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 OEU22026.1 - 4.2e-15 56.0 0.0 2.3e-14 53.5 0.0 2.1 2 1 0 2 2 2 1 MIF4G domain SDA1 PF05285.12 OEU22026.1 - 0.88 8.9 12.6 1.2 8.4 12.6 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 OEU22026.1 - 9.8 6.2 16.0 16 5.5 16.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AAA PF00004.29 OEU22027.1 - 1.2e-41 142.2 0.0 2.4e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OEU22027.1 - 7.8e-10 38.6 0.1 2.2e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OEU22027.1 - 2.4e-09 36.9 0.2 7.7e-09 35.2 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OEU22027.1 - 2.3e-07 31.4 1.9 7.6e-05 23.2 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OEU22027.1 - 7.5e-06 26.0 0.1 8.9e-05 22.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OEU22027.1 - 1.7e-05 25.0 0.2 5.9e-05 23.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OEU22027.1 - 5.6e-05 23.4 0.1 0.014 15.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OEU22027.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OEU22027.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 OEU22027.1 - 0.0015 17.9 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OEU22027.1 - 0.0016 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 OEU22027.1 - 0.0016 18.8 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 OEU22027.1 - 0.0023 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OEU22027.1 - 0.0042 16.6 0.0 0.0091 15.5 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 OEU22027.1 - 0.0075 16.0 0.1 0.052 13.3 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 OEU22027.1 - 0.011 16.0 2.7 0.018 15.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OEU22027.1 - 0.011 15.9 0.3 0.034 14.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain Prot_ATP_OB_N PF17758.1 OEU22027.1 - 0.012 15.2 0.6 0.031 13.9 0.1 1.9 3 0 0 3 3 1 0 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 OEU22027.1 - 0.012 16.1 0.0 0.012 16.1 0.0 2.7 3 2 0 3 3 1 0 AAA domain AAA_11 PF13086.6 OEU22027.1 - 0.018 14.9 5.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OEU22027.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OEU22027.1 - 0.022 14.1 0.2 0.088 12.1 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 OEU22027.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OEU22027.1 - 0.026 14.2 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU22027.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OEU22027.1 - 0.033 13.8 2.0 0.046 13.3 0.0 2.2 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 OEU22027.1 - 0.042 13.8 0.0 0.16 11.9 0.0 1.9 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 OEU22027.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 OEU22027.1 - 0.055 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 OEU22027.1 - 0.062 13.8 0.3 0.41 11.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter tRNA-synt_1 PF00133.22 OEU22027.1 - 0.074 11.3 0.1 0.12 10.6 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Sigma54_activ_2 PF14532.6 OEU22027.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF1043 PF06295.12 OEU22027.1 - 0.12 12.4 1.2 0.3 11.1 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Hydin_ADK PF17213.3 OEU22027.1 - 0.19 12.0 4.0 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Ribosomal_60s PF00428.19 OEU22027.1 - 1.1 9.9 16.8 4.1 8.1 16.8 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Menin PF05053.13 OEU22027.1 - 2.7 6.3 6.7 3.5 5.9 6.7 1.1 1 0 0 1 1 1 0 Menin DUF3391 PF11871.8 OEU22027.1 - 3.5 8.2 8.8 11 6.5 8.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) HABP4_PAI-RBP1 PF04774.15 OEU22027.1 - 3.6 8.5 15.1 6.1 7.7 15.1 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Tn7_TnsC_Int PF11426.8 OEU22030.1 - 0.06 13.5 0.5 0.14 12.3 0.5 1.6 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC PLAC8 PF04749.17 OEU22031.1 - 4.5e-06 27.6 0.0 8.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PLAC8 family PEP_mutase PF13714.6 OEU22032.1 - 4.7e-35 121.2 1.1 6.5e-35 120.7 1.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OEU22032.1 - 6.2e-10 38.2 0.6 1.1e-09 37.3 0.5 1.5 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OEU22033.1 - 5.9e-32 111.0 0.5 7.2e-32 110.7 0.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OEU22033.1 - 7.6e-10 37.9 1.0 1.9e-09 36.5 0.5 1.7 1 1 1 2 2 2 1 Isocitrate lyase family OSTbeta PF15048.6 OEU22037.1 - 0.0033 17.5 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein ETRAMP PF09716.10 OEU22037.1 - 0.039 14.0 0.2 0.084 12.9 0.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PHD PF00628.29 OEU22038.1 - 0.0064 16.4 6.8 0.0064 16.4 6.8 1.9 2 0 0 2 2 2 1 PHD-finger Ribosomal_L29 PF00831.23 OEU22039.1 - 3.6e-18 65.3 6.3 6.9e-18 64.4 1.4 2.3 2 1 0 2 2 2 2 Ribosomal L29 protein SET PF00856.28 OEU22040.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 SET domain DEAD PF00270.29 OEU22041.1 - 1.8e-30 106.0 0.0 3.2e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU22041.1 - 1.2e-25 90.1 0.1 8.1e-24 84.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22041.1 - 0.0025 17.9 0.1 0.0094 16.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OEU22041.1 - 0.0092 14.8 0.1 0.9 8.2 0.1 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SET PF00856.28 OEU22042.1 - 2.9e-11 44.0 0.8 2.2e-07 31.4 0.6 2.4 1 1 1 2 2 2 2 SET domain CRA PF06589.11 OEU22043.1 - 0.03 14.4 1.3 0.047 13.8 1.3 1.5 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) zf-U11-48K PF05253.12 OEU22043.1 - 0.12 12.3 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger PRAI PF00697.22 OEU22044.1 - 1.3e-40 139.3 0.1 4.5e-34 117.9 0.1 2.2 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IGPS PF00218.21 OEU22045.1 - 2.5e-66 223.4 0.2 3.6e-65 219.6 0.2 1.9 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase Transcrip_reg PF01709.20 OEU22045.1 - 0.072 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator OSR1_C PF12202.8 OEU22045.1 - 0.17 12.1 0.2 0.32 11.2 0.2 1.4 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain DAO PF01266.24 OEU22047.1 - 0.00057 19.6 0.5 0.001 18.7 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OEU22047.1 - 0.0041 16.4 2.9 7.2 5.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Telomerase_RBD PF12009.8 OEU22048.1 - 0.086 12.9 0.4 0.25 11.5 0.4 1.7 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Thioredoxin PF00085.20 OEU22050.1 - 9.6e-11 41.6 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OEU22050.1 - 0.00025 21.3 0.0 0.0004 20.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OEU22050.1 - 0.013 15.7 0.4 0.017 15.3 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU22050.1 - 0.018 15.5 0.1 0.04 14.4 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU22050.1 - 0.03 14.3 0.1 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 OEU22050.1 - 0.03 13.7 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family ZapB PF06005.12 OEU22051.1 - 0.069 13.6 4.8 0.76 10.3 0.3 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF4718 PF15842.5 OEU22051.1 - 5.2 6.8 13.0 0.43 10.4 6.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) RRM_1 PF00076.22 OEU22052.1 - 0.013 15.3 1.0 0.074 12.9 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF775 PF05603.12 OEU22053.1 - 2.3e-32 112.2 0.0 2.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) PipA PF07108.11 OEU22053.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 PipA protein HGTP_anticodon PF03129.20 OEU22054.1 - 5.5e-18 64.9 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OEU22054.1 - 2e-08 34.4 0.0 1.2e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TRI5 PF06330.11 OEU22054.1 - 0.042 12.7 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) AAA_26 PF13500.6 OEU22055.1 - 1.6e-10 41.2 0.0 7.9e-08 32.4 0.0 3.2 1 1 0 1 1 1 1 AAA domain PX PF00787.24 OEU22056.1 - 3e-20 72.3 1.0 7e-20 71.1 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 OEU22056.1 - 3.8e-10 39.7 8.2 5.7e-10 39.2 7.9 1.4 1 1 0 1 1 1 1 Vps5 C terminal like UPF0231 PF06062.11 OEU22056.1 - 0.0092 16.2 0.6 4.9 7.4 0.0 2.7 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0231) LOH1CR12 PF10158.9 OEU22056.1 - 0.078 13.0 1.2 1 9.4 0.0 2.6 1 1 2 3 3 3 0 Tumour suppressor protein Occludin_ELL PF07303.13 OEU22056.1 - 0.15 12.8 3.3 3.3 8.5 0.4 2.8 3 0 0 3 3 3 0 Occludin homology domain Seryl_tRNA_N PF02403.22 OEU22056.1 - 0.22 11.8 1.6 1.6 9.0 0.5 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 OEU22056.1 - 1.4 8.5 9.7 0.77 9.3 7.6 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit Pkinase PF00069.25 OEU22057.1 - 3.2e-39 134.9 0.0 5.4e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22057.1 - 1.5e-23 83.4 0.0 2.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 OEU22057.1 - 0.0017 18.9 1.7 0.0036 17.9 1.7 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1786 PF08735.10 OEU22057.1 - 0.0035 16.6 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative pyruvate format-lyase activating enzyme (DUF1786) YrbL-PhoP_reg PF10707.9 OEU22057.1 - 0.0078 15.8 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OEU22057.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like UvrB PF12344.8 OEU22057.1 - 0.098 12.5 0.4 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Ultra-violet resistance protein B Ribosomal_L30 PF00327.20 OEU22058.1 - 4.8e-06 26.4 0.1 7.4e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sigma_reg_N PF13800.6 OEU22060.1 - 0.0072 16.6 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Sigma factor regulator N-terminal Shisa PF13908.6 OEU22060.1 - 0.017 15.4 0.4 0.033 14.4 0.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3357 PF11837.8 OEU22060.1 - 0.11 12.9 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) bHLH-MYC_N PF14215.6 OEU22061.1 - 1.5e-08 35.1 0.0 6.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal Pro_isomerase PF00160.21 OEU22062.1 - 2.7e-47 161.0 0.1 3.2e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 OEU22063.1 - 7.6e-43 146.3 0.0 9e-42 142.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU22063.1 - 2.8e-25 88.8 0.0 8.9e-24 84.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22063.1 - 2.6e-07 30.8 0.0 5.9e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU22063.1 - 0.087 13.1 0.5 0.64 10.3 0.4 2.4 2 1 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 OEU22063.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S19 PF00203.21 OEU22064.1 - 1.1e-30 105.3 0.1 1.5e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SAM_1 PF00536.30 OEU22064.1 - 0.066 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glyco_transf_8 PF01501.20 OEU22065.1 - 0.16 11.5 1.7 4.4 6.8 1.7 2.3 1 1 0 1 1 1 0 Glycosyl transferase family 8 DUF4539 PF15072.6 OEU22066.1 - 0.0023 17.9 0.5 1.2 9.2 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4539) Nore1-SARAH PF16517.5 OEU22066.1 - 0.069 13.1 0.9 0.93 9.5 1.1 2.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain tRNA_anti-codon PF01336.25 OEU22066.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SIR2 PF02146.17 OEU22067.1 - 1.8e-13 50.8 0.0 3e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 Sir2 family DUF5108 PF17133.4 OEU22068.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5108) NESP55 PF06390.12 OEU22068.1 - 0.57 9.7 7.4 0.15 11.6 3.9 1.7 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) OxoDH_E1alpha_N PF12573.8 OEU22069.1 - 0.12 12.1 0.2 0.3 10.9 0.2 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Phage_GPL PF05926.11 OEU22069.1 - 0.51 10.3 4.8 2.3 8.2 1.2 2.8 3 0 0 3 3 3 0 Phage head completion protein (GPL) DUF5521 PF17659.1 OEU22071.1 - 0.08 10.8 1.1 0.087 10.7 1.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) ORC6 PF05460.13 OEU22071.1 - 0.16 11.2 6.7 0.21 10.8 6.7 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Antimicrobial24 PF16049.5 OEU22074.1 - 7.2 6.7 6.9 1.1 9.2 0.8 2.1 2 0 0 2 2 2 0 Frog antimicrobial peptide TPR_12 PF13424.6 OEU22075.1 - 5.7e-12 45.8 0.4 1.9e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.6 OEU22075.1 - 0.0017 17.8 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 OEU22075.1 - 0.013 15.6 0.0 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU22075.1 - 0.016 15.2 0.4 3.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU22075.1 - 0.072 13.0 0.2 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OEU22075.1 - 0.079 12.8 0.0 6.4 6.8 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat COX6B PF02297.17 OEU22076.1 - 3.3e-11 43.2 4.9 4.6e-11 42.8 4.9 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb EF-G-binding_N PF07299.11 OEU22076.1 - 0.069 13.7 0.1 0.1 13.1 0.1 1.2 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal AvrPto PF11592.8 OEU22076.1 - 0.088 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto UQ_con PF00179.26 OEU22077.1 - 3.2e-23 81.9 0.1 3.4e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OEU22077.1 - 1.3e-07 31.4 0.0 1.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OEU22077.1 - 0.0041 17.0 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 OEU22077.1 - 0.018 15.3 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain PBP_like_2 PF12849.7 OEU22078.1 - 5.7e-43 147.6 0.0 8.6e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain Adeno_E1B_19K PF01691.16 OEU22078.1 - 0.058 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen UT PF03253.14 OEU22079.1 - 8.2e-63 212.3 27.0 9.8e-63 212.0 27.0 1.1 1 0 0 1 1 1 1 Urea transporter DUF747 PF05346.11 OEU22080.1 - 2.8e-83 280.1 13.7 4e-83 279.5 13.7 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF588 PF04535.12 OEU22080.1 - 0.006 16.4 4.8 0.22 11.3 0.7 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF588) GATase PF00117.28 OEU22081.1 - 8.6e-09 35.4 0.0 1.1e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OEU22081.1 - 0.00089 18.9 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF883 PF05957.13 OEU22082.1 - 0.025 15.1 25.1 0.075 13.6 1.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FTZ PF03867.14 OEU22082.1 - 0.031 13.8 6.3 0.036 13.6 6.3 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SLC12 PF03522.15 OEU22082.1 - 0.069 12.2 2.6 0.087 11.8 2.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Mitofilin PF09731.9 OEU22082.1 - 0.087 11.7 22.7 0.1 11.4 22.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LTV PF04180.14 OEU22082.1 - 0.13 11.9 5.8 0.16 11.7 5.8 1.2 1 0 0 1 1 1 0 Low temperature viability protein eIF3_subunit PF08597.10 OEU22082.1 - 0.19 11.6 18.9 0.27 11.1 18.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RRN3 PF05327.11 OEU22082.1 - 0.22 10.0 0.9 0.25 9.8 0.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GREB1 PF15782.5 OEU22082.1 - 0.28 8.3 3.3 0.31 8.1 3.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sigma70_ner PF04546.13 OEU22082.1 - 0.68 9.8 11.3 0.89 9.4 11.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3093 PF11292.8 OEU22082.1 - 0.72 10.1 6.5 1.4 9.1 5.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3093) Presenilin PF01080.17 OEU22082.1 - 1.1 7.9 4.8 1.3 7.7 4.8 1.2 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 OEU22082.1 - 1.3 9.1 4.8 1.8 8.6 4.8 1.3 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 XRN_M PF17846.1 OEU22082.1 - 1.4 7.8 3.6 1.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain PepSY_TM PF03929.16 OEU22082.1 - 1.4 8.5 8.7 3.1 7.4 8.6 1.6 1 1 0 1 1 1 0 PepSY-associated TM region Ndc1_Nup PF09531.10 OEU22082.1 - 1.7 7.2 5.4 2.4 6.7 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aconitase PF00330.20 OEU22083.1 - 8.5e-155 516.2 0.0 1e-154 516.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OEU22083.1 - 4.1e-35 121.0 0.0 7.4e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TIG PF01833.24 OEU22083.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 IPT/TIG domain Glyco_tranf_2_4 PF13704.6 OEU22084.1 - 3.3e-05 24.3 0.4 8.1e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 OEU22084.1 - 0.0046 16.6 0.7 0.0068 16.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 ubiquitin PF00240.23 OEU22085.1 - 2.2e-33 113.8 1.6 2.3e-33 113.8 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin family Sod_Ni PF09055.11 OEU22085.1 - 1.1e-32 113.2 3.4 1.8e-32 112.6 3.4 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 OEU22085.1 - 6.1e-16 58.0 0.7 1e-15 57.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OEU22085.1 - 3.5e-05 24.2 0.1 0.00014 22.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OEU22085.1 - 0.0057 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OEU22085.1 - 0.016 15.3 0.2 0.066 13.3 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OEU22085.1 - 0.018 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 OEU22085.1 - 0.044 14.3 0.0 0.086 13.4 0.0 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OEU22085.1 - 0.11 12.5 1.7 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-like domain PIP5K PF01504.18 OEU22087.1 - 7.5e-41 140.2 0.0 3.3e-31 108.5 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 OEU22088.1 - 2.8e-18 65.8 11.8 3.1e-18 65.6 11.8 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OEU22088.1 - 0.24 11.6 9.9 0.29 11.4 9.9 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CRD PF17979.1 OEU22088.1 - 0.58 10.3 11.9 0.92 9.6 11.9 1.5 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions GCIP PF13324.6 OEU22089.1 - 3.1e-31 108.9 0.3 5.4e-31 108.2 0.3 1.4 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting GP24_25 PF17388.2 OEU22089.1 - 3.3 7.7 9.5 0.25 11.3 0.4 3.0 2 1 1 3 3 3 0 Tail assembly gene products 24 & 25 TRAPPC9-Trs120 PF08626.11 OEU22090.1 - 4.2e-22 77.4 3.8 1.6e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit zf-CCHC_3 PF13917.6 OEU22090.1 - 0.53 10.3 2.3 6.9 6.7 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle HAD_2 PF13419.6 OEU22091.1 - 7.7e-20 71.7 0.3 2.7e-19 70.0 0.3 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OEU22091.1 - 6.8e-12 46.1 0.0 4.5e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU22091.1 - 1.9e-08 34.2 0.0 3.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OEU22091.1 - 1.4e-06 28.3 0.0 3.7e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OEU22091.1 - 1e-05 26.0 0.0 1.4e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OEU22091.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 Acid Phosphatase PGP_phosphatase PF09419.10 OEU22091.1 - 0.023 14.3 0.4 7.4 6.1 0.0 2.7 1 1 0 2 2 2 0 Mitochondrial PGP phosphatase Ank_2 PF12796.7 OEU22092.1 - 4.3e-19 68.9 0.1 2.2e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU22092.1 - 6e-16 58.3 0.2 6.2e-07 29.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU22092.1 - 7.8e-14 51.9 1.5 0.0013 19.3 0.0 3.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22092.1 - 3e-13 48.7 0.0 0.0036 17.7 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OEU22092.1 - 7.6e-12 45.1 0.3 0.003 17.9 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat ThiS PF02597.20 OEU22092.1 - 0.088 13.5 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 ThiS family DUF1282 PF06930.12 OEU22093.1 - 0.38 10.5 11.0 0.6 9.9 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) EF-hand_7 PF13499.6 OEU22094.1 - 0.00037 20.9 0.8 0.71 10.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU22094.1 - 0.0073 15.8 0.6 0.71 9.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU22094.1 - 0.02 14.8 0.3 1.9 8.6 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 OEU22094.1 - 0.066 13.1 0.7 0.66 9.9 0.5 2.3 2 1 0 2 2 2 0 EF-hand domain pair Proteasome PF00227.26 OEU22095.1 - 1.3e-13 50.9 0.0 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PI31_Prot_C PF08577.11 OEU22096.1 - 0.13 13.4 14.3 0.1 13.8 11.7 2.2 1 1 0 1 1 1 0 PI31 proteasome regulator DUF1295 PF06966.12 OEU22098.1 - 9.3e-19 67.9 8.0 1.2e-15 57.7 1.6 3.6 2 2 1 3 3 3 3 Protein of unknown function (DUF1295) DUF3446 PF11928.8 OEU22098.1 - 0.19 12.1 5.0 0.85 10.0 2.7 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF508 PF04370.12 OEU22098.1 - 0.54 10.0 2.6 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF508) AAA_23 PF13476.6 OEU22099.1 - 3.9e-08 34.0 1.6 3.9e-08 34.0 1.6 3.4 3 2 0 3 3 3 1 AAA domain SMC_N PF02463.19 OEU22099.1 - 5.4e-07 29.3 4.5 8.9e-06 25.3 4.5 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Metallophos PF00149.28 OEU22099.1 - 1.1e-05 26.0 0.1 2.6e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SbcCD_C PF13558.6 OEU22099.1 - 0.0014 18.8 0.0 0.0058 16.8 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Succ_DH_flav_C PF02910.20 OEU22099.1 - 0.07 13.1 0.4 0.36 10.8 0.2 2.4 1 1 0 1 1 1 0 Fumarate reductase flavoprotein C-term PDZ PF00595.24 OEU22100.1 - 0.00018 21.8 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU22100.1 - 0.0011 19.3 0.2 0.018 15.4 0.0 2.3 1 1 1 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OEU22100.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 OEU22100.1 - 0.0023 18.3 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain eIF2A PF08662.11 OEU22101.1 - 3e-44 151.2 5.7 1e-39 136.5 0.9 4.7 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 OEU22101.1 - 8.7e-07 28.7 0.1 2.1e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 OEU22101.1 - 2.4e-05 22.6 0.0 0.00082 17.5 0.0 2.4 1 1 0 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 OEU22101.1 - 5.3e-05 23.4 0.0 4.5 7.6 0.0 5.7 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain FlxA PF14282.6 OEU22101.1 - 0.088 12.8 1.9 0.2 11.7 1.9 1.5 1 0 0 1 1 1 0 FlxA-like protein Y_phosphatase3 PF13350.6 OEU22102.1 - 3.4e-42 145.0 0.0 1.6e-40 139.5 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OEU22102.1 - 0.0049 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family BTB PF00651.31 OEU22103.1 - 1.1e-06 28.9 0.0 0.00021 21.5 0.0 3.5 3 2 0 3 3 3 2 BTB/POZ domain CNOT1_TTP_bind PF16417.5 OEU22104.1 - 0.1 11.8 0.4 0.15 11.2 0.4 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain SDA1 PF05285.12 OEU22104.1 - 5.9 6.2 13.4 7.4 5.9 13.4 1.1 1 0 0 1 1 1 0 SDA1 GDA1_CD39 PF01150.17 OEU22105.1 - 3.2e-56 190.8 0.1 1.8e-29 102.7 0.0 3.1 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ribosomal_60s PF00428.19 OEU22106.1 - 1.9e-13 50.8 10.3 2.5e-13 50.4 10.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ank_5 PF13857.6 OEU22107.1 - 7.5e-12 45.2 0.4 0.00027 21.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU22107.1 - 9.1e-09 35.8 0.0 0.00032 21.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OEU22107.1 - 1.1e-06 28.7 1.9 0.22 12.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OEU22107.1 - 2.8e-06 27.7 0.2 0.0014 19.1 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22107.1 - 3.8e-06 26.8 0.4 2.3 9.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Takusan PF04822.13 OEU22108.1 - 0.009 15.9 6.7 0.009 15.9 6.7 2.1 1 1 1 2 2 2 1 Takusan Cep57_CLD_2 PF14197.6 OEU22108.1 - 0.0095 16.0 2.2 0.0095 16.0 2.2 2.2 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 Tup_N PF08581.10 OEU22108.1 - 0.019 15.3 11.7 0.052 13.8 2.8 2.8 1 1 2 3 3 3 0 Tup N-terminal FUSC PF04632.12 OEU22108.1 - 0.06 11.9 5.3 0.077 11.5 5.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2683 PF10884.8 OEU22108.1 - 0.07 13.4 1.6 0.91 9.8 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2683) TMF_TATA_bd PF12325.8 OEU22108.1 - 0.18 12.0 19.6 0.029 14.6 10.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 OEU22108.1 - 0.21 12.0 17.2 0.18 12.2 15.1 1.8 1 1 1 2 2 2 0 Fez1 Nitr_red_assoc PF09655.10 OEU22108.1 - 0.22 12.1 7.2 0.1 13.2 3.8 1.8 1 1 1 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Spc7 PF08317.11 OEU22108.1 - 1 8.2 22.3 0.42 9.5 4.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 OEU22108.1 - 6.3 7.3 12.2 7.3 7.1 2.9 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 OEU22108.1 - 8.7 6.9 10.3 2.5 8.6 0.5 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fucokinase PF07959.12 OEU22109.1 - 3.3e-49 167.9 0.6 6.2e-49 167.0 0.6 1.4 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 OEU22109.1 - 0.0024 18.2 0.0 0.0084 16.4 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Lambda_tail_I PF06805.12 OEU22109.1 - 0.12 12.7 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I Methyltransf_31 PF13847.6 OEU22110.1 - 1.5e-29 102.7 0.0 2.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU22110.1 - 1.7e-17 63.9 0.0 3.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU22110.1 - 7.9e-17 61.7 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU22110.1 - 3.3e-12 46.2 0.0 5.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OEU22110.1 - 8.2e-12 45.3 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU22110.1 - 8.3e-11 42.5 0.1 1.6e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OEU22110.1 - 2e-07 31.0 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 OEU22110.1 - 0.0001 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OEU22110.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 OEU22110.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Fibrillarin PF01269.17 OEU22110.1 - 0.043 12.9 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DOT1 PF08123.13 OEU22110.1 - 0.092 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.15 OEU22110.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Pkinase PF00069.25 OEU22112.1 - 1.5e-48 165.5 1.8 1.8e-48 165.2 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22112.1 - 1.2e-36 126.4 0.0 2e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OEU22112.1 - 4.5e-09 36.6 5.4 1.9e-07 31.5 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU22112.1 - 6.5e-07 28.8 0.5 0.053 13.5 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OEU22112.1 - 7e-07 28.4 0.1 0.023 14.2 0.0 3.5 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 OEU22112.1 - 1e-06 28.3 0.1 7.9e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU22112.1 - 5.7e-06 25.4 0.1 5.7e-06 25.4 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_8 PF13833.6 OEU22112.1 - 2.1e-05 24.3 0.1 7.3e-05 22.5 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair YrbL-PhoP_reg PF10707.9 OEU22112.1 - 0.015 14.8 0.1 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL EF-hand_4 PF12763.7 OEU22112.1 - 0.051 13.5 0.1 0.3 11.1 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Nuc_sug_transp PF04142.15 OEU22113.1 - 1.3e-86 290.6 11.6 1.5e-86 290.4 11.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OEU22113.1 - 1.2e-10 41.1 10.6 3.3e-10 39.7 10.6 1.8 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 OEU22113.1 - 1e-06 28.2 6.3 1.7e-06 27.5 6.2 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 OEU22113.1 - 0.00034 19.7 1.8 0.00034 19.7 1.8 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OEU22113.1 - 0.00067 19.8 3.0 0.00067 19.8 3.0 2.7 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 OEU22113.1 - 0.29 10.5 15.3 0.09 12.1 4.4 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family 2Fe-2S_thioredx PF01257.19 OEU22114.1 - 2.6e-57 192.7 0.3 3.3e-57 192.4 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Ssu72 PF04722.13 OEU22114.1 - 0.0047 16.5 0.1 0.0092 15.6 0.1 1.4 1 0 0 1 1 1 1 Ssu72-like protein G6PD_C PF02781.16 OEU22115.1 - 1.2e-91 306.9 0.0 1.7e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OEU22115.1 - 1.2e-52 179.1 0.0 2e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain TPR_12 PF13424.6 OEU22116.1 - 7e-17 61.5 0.4 1.1e-06 28.9 0.0 4.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU22116.1 - 4.2e-08 32.7 4.9 1.2 9.4 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OEU22116.1 - 4.4e-08 32.6 3.3 0.055 13.3 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU22116.1 - 1.2e-06 28.1 2.3 0.0003 20.6 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU22116.1 - 5.7e-06 25.9 0.1 0.49 10.1 0.0 4.6 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.6 OEU22116.1 - 0.00066 20.1 0.3 0.12 12.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OEU22116.1 - 0.00075 20.1 1.0 8.6 7.5 0.0 4.7 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OEU22116.1 - 0.0018 18.2 1.9 4.7 7.5 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU22116.1 - 0.013 15.7 0.6 0.11 12.7 0.1 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 OEU22116.1 - 0.019 14.4 0.1 0.41 10.2 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_16 PF13432.6 OEU22116.1 - 0.019 15.6 1.3 4.5 8.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU22116.1 - 0.023 15.3 2.3 95 4.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_U57 PF05582.12 OEU22116.1 - 0.076 12.3 8.1 0.023 14.0 3.5 2.1 2 0 0 2 2 2 0 YabG peptidase U57 TPR_17 PF13431.6 OEU22116.1 - 0.082 13.3 0.0 0.54 10.8 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PIEZO PF15917.5 OEU22116.1 - 6.7 6.1 13.0 0.3 10.5 5.9 2.1 2 0 0 2 2 2 0 Piezo DUF4662 PF15578.6 OEU22116.1 - 9.7 5.9 12.8 0.37 10.5 6.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) SseC PF04888.12 OEU22117.1 - 0.27 10.8 24.3 3.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF1829 PF08862.10 OEU22118.1 - 0.098 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1829 zf-Nse PF11789.8 OEU22119.1 - 7.9e-13 48.0 0.6 1.4e-12 47.3 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OEU22119.1 - 1.7e-05 24.6 0.8 4.1e-05 23.3 0.8 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 OEU22119.1 - 0.006 16.3 0.3 0.014 15.2 0.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger AAA_assoc_C PF09821.9 OEU22119.1 - 0.027 15.0 0.4 5.6 7.5 0.0 2.6 3 0 0 3 3 3 0 C-terminal AAA-associated domain zf-C3HC4 PF00097.25 OEU22119.1 - 0.049 13.5 0.3 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 OEU22119.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_UBOX PF13445.6 OEU22119.1 - 0.092 12.8 0.6 0.23 11.5 0.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OEU22119.1 - 0.27 11.6 1.5 0.62 10.4 1.5 1.7 1 0 0 1 1 1 0 Ring finger domain Arc_PepC_II PF06847.11 OEU22119.1 - 0.67 10.5 2.3 5.3 7.6 0.2 2.9 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II PAP_fibrillin PF04755.12 OEU22120.1 - 0.00021 21.3 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 PAP_fibrillin Ank_2 PF12796.7 OEU22121.1 - 2.5e-20 72.8 0.0 8e-09 36.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU22121.1 - 1.2e-10 41.5 0.0 0.0014 18.9 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OEU22121.1 - 1.9e-10 41.0 0.0 7.4e-05 23.2 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22121.1 - 3e-10 39.4 0.1 0.72 10.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OEU22121.1 - 2e-06 28.0 0.6 0.092 13.2 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OEU22122.1 - 0.00062 20.0 0.0 0.0035 17.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22122.1 - 0.018 15.5 0.0 12 6.9 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat DUF3748 PF12566.8 OEU22122.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Rx_N PF18052.1 OEU22122.1 - 8.4 6.7 15.7 1.9 8.8 5.9 2.7 1 1 2 3 3 3 0 Rx N-terminal domain Asp_Arg_Hydrox PF05118.15 OEU22123.1 - 5.9e-40 136.7 0.0 1.4e-39 135.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase zf-MYND PF01753.18 OEU22123.1 - 0.0053 16.8 10.0 0.0053 16.8 10.0 2.5 2 0 0 2 2 2 1 MYND finger Cupin_2 PF07883.11 OEU22123.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Zn_ribbon_recom PF13408.6 OEU22123.1 - 4.1 8.0 7.3 29 5.3 3.4 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain NAD_binding_1 PF00175.21 OEU22124.1 - 9.8e-17 61.6 0.0 1.9e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OEU22124.1 - 0.052 13.7 0.0 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Ferric reductase NAD binding domain TLD PF07534.16 OEU22125.1 - 2.7e-11 43.9 0.0 5.2e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 TLD PPR_2 PF13041.6 OEU22126.1 - 1.9e-11 44.0 1.1 0.21 11.8 0.0 6.6 5 2 1 6 6 6 3 PPR repeat family PPR PF01535.20 OEU22126.1 - 2e-07 30.8 12.2 0.0047 17.1 0.0 7.7 8 3 0 8 8 8 2 PPR repeat PPR_3 PF13812.6 OEU22126.1 - 4.8e-06 26.6 0.0 1.8 8.7 0.0 5.4 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Wzy_C_2 PF11846.8 OEU22126.1 - 0.016 15.1 0.0 3.7 7.4 0.0 3.0 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF1722 PF08349.11 OEU22126.1 - 0.017 15.4 0.1 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PPR_1 PF12854.7 OEU22126.1 - 0.029 14.1 8.0 0.14 11.9 0.0 5.0 6 0 0 6 6 6 0 PPR repeat CNDH2_C PF16858.5 OEU22126.1 - 0.042 13.7 1.4 0.073 12.9 1.4 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4611 PF15387.6 OEU22126.1 - 2.4 8.4 6.1 25 5.2 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RTC PF01137.21 OEU22127.1 - 2.6e-37 128.2 0.0 4.1e-36 124.3 0.0 2.0 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OEU22127.1 - 2.2e-24 85.9 0.0 3.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pyridoxal_deC PF00282.19 OEU22128.1 - 6.3e-65 219.3 0.0 7.5e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Phage_attach PF05354.11 OEU22128.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage Head-Tail Attachment Aminotran_5 PF00266.19 OEU22128.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Peptidase_C12 PF01088.21 OEU22129.1 - 7.5e-54 182.7 0.0 8.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ferrochelatase PF00762.19 OEU22130.1 - 2.9e-107 358.4 0.0 3.3e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 OEU22130.1 - 0.001 19.4 0.0 0.73 10.2 0.0 2.8 3 1 0 3 3 3 2 CbiX DnaJ PF00226.31 OEU22131.1 - 2e-12 47.0 0.1 2e-12 47.0 0.1 3.2 4 1 0 4 4 4 1 DnaJ domain DUF1664 PF07889.12 OEU22131.1 - 0.017 15.2 6.1 0.017 15.2 6.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NDUFA12 PF05071.16 OEU22131.1 - 0.16 12.8 0.4 0.16 12.8 0.4 2.4 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 BBS1 PF14779.6 OEU22131.1 - 2.7 7.4 9.1 0.55 9.6 4.6 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 1 MgtE_N PF03448.17 OEU22131.1 - 4.6 7.9 9.6 0.29 11.7 2.3 3.0 3 1 0 3 3 3 0 MgtE intracellular N domain RNA_pol_Rbc25 PF08292.12 OEU22132.1 - 2.2e-13 50.6 0.1 4.6e-13 49.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OEU22132.1 - 1.3e-08 35.1 0.1 3.8e-08 33.6 0.0 1.8 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OEU22132.1 - 0.084 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain WD40 PF00400.32 OEU22133.1 - 6.7e-11 42.6 13.5 0.0004 21.1 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22133.1 - 2.2e-10 40.7 0.8 9.4e-05 22.6 0.0 4.6 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 OEU22133.1 - 0.038 14.2 0.6 0.1 12.9 0.6 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Vac_Fusion PF02346.16 OEU22133.1 - 0.14 11.8 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 YabA PF06156.13 OEU22133.1 - 0.22 12.2 2.3 0.44 11.2 1.4 1.9 2 0 0 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 OEU22133.1 - 0.25 11.7 1.5 0.63 10.4 1.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family RRM_1 PF00076.22 OEU22134.1 - 7.3e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3449 PF11931.8 OEU22134.1 - 0.16 11.8 4.1 0.047 13.5 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Vfa1 PF08432.10 OEU22134.1 - 9.7 6.5 11.6 31 4.8 6.4 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Bromodomain PF00439.25 OEU22135.1 - 3.8e-16 58.9 0.0 6.2e-16 58.2 0.0 1.4 2 0 0 2 2 2 1 Bromodomain Pyr_redox_2 PF07992.14 OEU22136.1 - 2.9e-37 128.5 0.0 2.1e-36 125.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU22136.1 - 7.7e-06 26.4 0.1 0.00028 21.4 0.0 3.0 4 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 OEU22137.1 - 0.076 11.9 0.2 0.26 10.1 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.13 OEU22137.1 - 2 8.2 3.6 5.3 6.8 3.6 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold HMG_box PF00505.19 OEU22139.1 - 5.9e-06 26.6 0.0 7.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU22139.1 - 0.00011 22.7 0.0 0.00012 22.6 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain efb-c PF12199.8 OEU22139.1 - 0.084 12.9 0.5 0.1 12.7 0.1 1.5 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal LSM PF01423.22 OEU22140.1 - 3.8e-18 64.9 0.1 4.7e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Metallophos PF00149.28 OEU22141.1 - 2e-36 126.4 0.1 2.4e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OEU22141.1 - 1.1e-15 57.8 0.2 2.2e-15 56.8 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Herpes_UL52 PF03121.15 OEU22142.1 - 1.8e-05 24.6 0.2 5.3e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Acetyltransf_1 PF00583.25 OEU22143.1 - 1.8e-11 44.3 0.0 7.7e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU22143.1 - 2.1e-08 34.1 0.0 2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU22143.1 - 4.1e-08 33.5 0.0 9.2e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU22143.1 - 0.00012 22.0 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OEU22143.1 - 0.0024 18.0 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOSC PF03473.17 OEU22144.1 - 7e-24 84.3 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OEU22144.1 - 4.1e-11 42.8 0.0 1.1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain TruD PF01142.18 OEU22145.1 - 4.4e-72 243.2 1.3 7.4e-70 235.9 1.0 3.2 2 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) CEL_III_C PF18054.1 OEU22146.1 - 2.4 8.2 9.7 2.9 7.9 1.2 3.2 3 0 0 3 3 3 0 CEL-III C-terminal Peptidase_C92 PF05708.12 OEU22147.1 - 5.8e-11 42.8 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1697 PF08002.11 OEU22148.1 - 9.9e-36 123.2 0.9 3.8e-35 121.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1697) DUF3083 PF11281.8 OEU22148.1 - 0.019 14.3 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) 7tm_3 PF00003.22 OEU22149.1 - 2.4e-24 86.4 17.4 3.4e-24 85.9 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR SBP_bac_1 PF01547.25 OEU22149.1 - 7.3e-06 26.1 0.1 2.5e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein PgaD PF13994.6 OEU22149.1 - 7.2 6.7 5.4 1.3 9.1 0.9 2.0 2 0 0 2 2 2 0 PgaD-like protein 7tm_3 PF00003.22 OEU22150.1 - 3.1e-37 128.5 19.5 5e-37 127.9 19.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR SBP_bac_8 PF13416.6 OEU22150.1 - 5.7e-07 29.6 0.0 1.7e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein COQ9 PF08511.11 OEU22150.1 - 8.8e-06 25.4 0.1 2.5e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 COQ9 SBP_bac_1 PF01547.25 OEU22150.1 - 1.9e-05 24.8 0.1 0.0017 18.4 0.1 2.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein PCI PF01399.27 OEU22151.1 - 1.5e-08 35.1 0.0 8.1e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain Sigma70_r4 PF04545.16 OEU22151.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DHHC PF01529.20 OEU22154.1 - 1.5e-22 80.1 9.2 1.6e-22 80.1 9.2 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase RRM_1 PF00076.22 OEU22155.1 - 9e-17 60.7 0.1 1.5e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2559 PF10832.8 OEU22155.1 - 0.048 13.7 0.6 0.086 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) RRM_7 PF16367.5 OEU22155.1 - 0.087 12.9 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Glyoxalase_4 PF13669.6 OEU22156.1 - 0.0084 16.4 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HA PF03457.14 OEU22157.1 - 1.9e-41 140.2 2.2 1.3e-20 73.5 0.4 2.3 2 0 0 2 2 2 2 Helicase associated domain DUF4882 PF16223.5 OEU22157.1 - 0.0045 16.3 0.1 0.007 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4882) Histone_H2A_C PF16211.5 OEU22158.1 - 3.1e-20 71.6 2.2 5.9e-20 70.7 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OEU22158.1 - 1.1e-14 54.9 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OEU22158.1 - 0.00042 20.5 0.0 0.00071 19.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU22159.1 - 4.8e-20 72.2 0.6 5.9e-20 72.0 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OEU22159.1 - 0.00029 21.3 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 OEU22159.1 - 0.0025 17.9 0.2 0.003 17.6 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CBFD_NFYB_HMF PF00808.23 OEU22159.1 - 0.0049 17.1 1.2 0.0055 17.0 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MM_CoA_mutase PF01642.22 OEU22160.1 - 2.2e-214 712.8 1.1 2.6e-214 712.5 1.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 OEU22160.1 - 8.7e-13 48.4 0.1 2e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 B12 binding domain Histone PF00125.24 OEU22161.1 - 5.3e-54 182.1 1.0 5.9e-54 182.0 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OEU22161.1 - 0.00017 22.2 1.1 0.0002 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OEU22161.1 - 0.00076 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU22161.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OEU22161.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OEU22161.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 OEU22162.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU22162.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OEU22162.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OEU22162.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU22162.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OEU22162.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OEU22162.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OEU22162.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) PAP_fibrillin PF04755.12 OEU22163.1 - 1.1e-08 35.2 0.3 2.5e-07 30.8 0.3 2.2 1 1 0 1 1 1 1 PAP_fibrillin MAM33 PF02330.16 OEU22163.1 - 0.058 13.3 4.5 0.11 12.5 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein DUF2722 PF10846.8 OEU22163.1 - 0.53 9.2 8.0 0.83 8.5 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) KN17_SH3 PF18131.1 OEU22164.1 - 3.2e-09 36.7 0.7 6.7e-09 35.7 0.2 1.8 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain Na_H_Exchanger PF00999.21 OEU22165.1 - 1.4e-59 201.8 44.5 2.6e-58 197.7 47.7 1.4 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 OEU22165.1 - 1.1e-19 70.8 0.2 3.2e-19 69.3 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain AdoHcyase_NAD PF00670.21 OEU22165.1 - 0.021 14.9 0.3 0.041 13.9 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Adap_comp_sub PF00928.21 OEU22166.1 - 2.2e-88 296.1 0.0 2.7e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OEU22166.1 - 6.5e-06 26.1 0.2 1.3e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 OEU22166.1 - 0.021 14.9 0.6 0.072 13.1 0.6 1.9 1 1 0 1 1 1 0 Regulated-SNARE-like domain FUN14 PF04930.15 OEU22167.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 FUN14 family Metallophos PF00149.28 OEU22169.1 - 1.2e-06 29.2 0.1 2e-06 28.5 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_11 PF08241.12 OEU22170.1 - 5.9e-19 68.5 0.0 9.4e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU22170.1 - 8.8e-18 64.8 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU22170.1 - 1.2e-13 51.6 0.0 1.8e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU22170.1 - 6.4e-12 45.5 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU22170.1 - 2e-11 43.7 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OEU22170.1 - 3.3e-07 30.3 0.0 5.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OEU22170.1 - 0.023 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 OEU22170.1 - 0.034 14.1 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OEU22170.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 OEU22170.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Band_7 PF01145.25 OEU22171.1 - 1.4e-26 93.6 2.7 2.3e-26 92.9 2.6 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Fe-ADH PF00465.19 OEU22171.1 - 0.044 12.6 0.1 0.078 11.8 0.0 1.4 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase LRR_8 PF13855.6 OEU22173.1 - 4.7e-27 93.5 62.1 6.4e-07 29.0 2.6 9.8 6 3 2 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 OEU22173.1 - 3.6e-14 52.6 68.9 4.9e-05 23.6 5.1 10.8 9 2 2 11 11 11 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU22173.1 - 0.0049 17.2 53.1 1.6 9.6 0.1 14.4 17 1 0 17 17 17 3 Leucine Rich Repeat DUF3718 PF12514.8 OEU22173.1 - 0.12 12.5 0.2 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) LRR_5 PF13306.6 OEU22173.1 - 0.4 10.6 11.6 0.2 11.6 0.4 4.0 3 2 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) TbpB_B_D PF01298.18 OEU22173.1 - 0.56 10.6 1.6 5.6 7.4 0.1 3.4 4 1 1 5 5 5 0 C-lobe and N-lobe beta barrels of Tf-binding protein B LRR_9 PF14580.6 OEU22173.1 - 2.2 7.8 11.5 6.4 6.2 1.7 4.1 3 1 1 4 4 4 0 Leucine-rich repeat TPR_12 PF13424.6 OEU22174.1 - 3.8e-10 39.9 0.2 0.00012 22.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU22174.1 - 2e-06 27.5 0.4 0.2 11.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU22174.1 - 0.0015 18.3 0.8 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OEU22174.1 - 0.0064 16.3 3.8 0.58 10.1 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU22174.1 - 0.061 13.6 0.8 37 4.9 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 OEU22174.1 - 0.069 12.8 7.3 0.09 12.4 7.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Trigger_N PF05697.13 OEU22175.1 - 0.00046 20.5 0.5 0.00079 19.8 0.5 1.6 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) LYRIC PF15686.5 OEU22175.1 - 0.0076 15.9 2.6 0.0076 15.9 2.6 1.4 2 0 0 2 2 2 1 Lysine-rich CEACAM1 co-isolated protein family FAM176 PF14851.6 OEU22175.1 - 0.089 12.5 0.3 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 OEU22175.1 - 0.48 10.2 6.7 0.77 9.5 6.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Glycos_transf_2 PF00535.26 OEU22177.1 - 1.2e-37 129.4 0.0 1.5e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OEU22177.1 - 9.7e-19 68.2 0.0 1.2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OEU22177.1 - 7.2e-08 32.1 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 OEU22177.1 - 4.8e-06 26.3 0.0 5.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GFO_IDH_MocA PF01408.22 OEU22178.1 - 1e-15 58.6 0.0 2.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold G6PD_N PF00479.22 OEU22178.1 - 0.04 14.5 0.0 0.065 13.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain OCRE PF17780.1 OEU22179.1 - 5.6e-12 45.5 2.7 1.6e-11 44.1 2.7 1.8 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 OEU22179.1 - 0.00027 20.7 0.2 0.00061 19.6 0.2 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 OEU22179.1 - 0.087 13.1 0.4 0.087 13.1 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 OEU22179.1 - 0.093 12.8 0.1 0.093 12.8 0.1 3.1 3 1 0 3 3 3 0 G-patch domain DUF393 PF04134.12 OEU22180.1 - 9.5e-09 36.6 0.0 1.4e-08 36.1 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function, DUF393 TP1 PF02079.16 OEU22181.1 - 0.038 13.9 0.4 0.078 12.9 0.4 1.5 1 0 0 1 1 1 0 Nuclear transition protein 1 DLIC PF05783.11 OEU22181.1 - 0.24 10.2 1.9 0.29 9.9 1.9 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2015 PF09435.10 OEU22182.1 - 0.078 12.8 1.8 3.3 7.6 0.0 2.9 1 1 2 3 3 3 0 Fungal protein of unknown function (DUF2015) DUF4519 PF15012.6 OEU22182.1 - 0.11 12.6 1.1 0.23 11.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) BAG PF02179.16 OEU22183.1 - 6.8e-05 23.2 1.4 9.5e-05 22.8 0.8 1.7 1 1 0 1 1 1 1 BAG domain Glyco_hydro_28 PF00295.17 OEU22184.1 - 2.4e-12 46.6 0.3 1.1e-11 44.4 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Headcase PF16002.5 OEU22184.1 - 0.045 13.2 0.2 0.065 12.7 0.2 1.2 1 0 0 1 1 1 0 Headcase protein Beta_helix PF13229.6 OEU22184.1 - 0.096 12.5 1.6 0.48 10.3 0.1 2.0 2 0 0 2 2 2 0 Right handed beta helix region Sen15 PF09631.10 OEU22185.1 - 0.044 14.1 0.6 0.45 10.8 0.0 2.8 3 0 0 3 3 3 0 Sen15 protein Nucleoporin_FG PF13634.6 OEU22186.1 - 0.86 10.5 25.3 0.18 12.7 14.7 2.3 1 1 1 2 2 2 0 Nucleoporin FG repeat region Stc1 PF12898.7 OEU22188.1 - 0.0041 17.6 0.9 0.0089 16.5 0.9 1.6 1 0 0 1 1 1 1 Stc1 domain Mpp10 PF04006.12 OEU22188.1 - 0.14 10.6 8.4 0.19 10.2 8.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 OEU22188.1 - 0.85 7.8 7.7 1.1 7.4 7.7 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 OEU22188.1 - 6 7.3 17.5 0.41 11.1 12.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 OEU22188.1 - 6.2 6.8 12.2 0.24 11.4 5.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal rve PF00665.26 OEU22190.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Auts2 PF15336.6 OEU22191.1 - 0.72 9.9 2.6 14 5.7 1.2 2.1 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Methyltransf_11 PF08241.12 OEU22192.1 - 6.2e-07 30.0 0.0 1.9e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 OEU22192.1 - 0.00065 19.3 0.0 0.0009 18.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 OEU22192.1 - 0.00082 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OEU22192.1 - 0.0028 18.3 0.0 0.0064 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU22192.1 - 0.0084 16.8 0.4 0.017 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU22192.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OEU22192.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 OEU22192.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF4756 PF15948.5 OEU22192.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) tRNA-synt_1g PF09334.11 OEU22193.1 - 2.4e-95 319.6 0.7 3.7e-54 184.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OEU22193.1 - 3.1e-28 98.4 8.3 5.9e-20 71.1 0.0 3.4 2 1 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 OEU22193.1 - 1.3e-27 95.7 0.2 2.5e-27 94.8 0.2 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 OEU22193.1 - 1.4e-13 50.9 0.1 2.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 OEU22193.1 - 3.3e-05 23.9 0.1 8.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 OEU22193.1 - 0.00012 21.1 0.0 0.00084 18.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF5590 PF17881.1 OEU22193.1 - 0.082 13.0 0.0 0.35 11.0 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) RWD PF05773.22 OEU22194.1 - 2.4e-15 56.8 0.7 2.4e-15 56.8 0.7 1.7 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 OEU22194.1 - 7 7.2 16.3 0.063 13.8 4.0 2.6 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Ras PF00071.22 OEU22195.1 - 1.5e-58 197.0 0.2 1.7e-58 196.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU22195.1 - 9.2e-36 122.7 0.2 1.3e-35 122.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU22195.1 - 3.7e-17 62.3 0.1 4.4e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OEU22195.1 - 7.3e-08 32.0 0.1 8.7e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OEU22195.1 - 1.1e-06 28.7 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU22195.1 - 1.3e-05 24.9 0.2 5.2e-05 22.9 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OEU22195.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OEU22195.1 - 0.0017 18.2 0.0 0.02 14.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 OEU22195.1 - 0.079 12.2 0.1 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 OEU22195.1 - 0.095 12.6 0.1 30 4.4 0.0 2.8 1 1 2 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 OEU22195.1 - 0.1 12.3 0.0 6.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OEU22195.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Neurensin PF14927.6 OEU22196.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Neurensin MSC PF09402.10 OEU22196.1 - 0.084 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain SPX PF03105.19 OEU22196.1 - 0.11 12.3 2.7 0.21 11.5 2.7 1.4 1 1 0 1 1 1 0 SPX domain SOG2 PF10428.9 OEU22196.1 - 2.5 7.2 17.9 3.1 6.9 16.5 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein SPOUT_MTase PF02590.17 OEU22197.1 - 1e-33 116.5 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase DUF771 PF05595.11 OEU22197.1 - 0.048 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF771) SPRY PF00622.28 OEU22198.1 - 2.4e-21 76.1 0.9 5.1e-21 75.0 0.3 1.9 2 0 0 2 2 2 1 SPRY domain SH3_5 PF08460.10 OEU22199.1 - 0.14 12.3 0.7 0.34 11.0 0.0 2.0 3 0 0 3 3 3 0 Bacterial SH3 domain UQ_con PF00179.26 OEU22200.1 - 3.7e-20 72.0 0.0 4.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CENP-T_C PF15511.6 OEU22201.1 - 9.6e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU22201.1 - 0.00017 21.9 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OEU22201.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OEU22201.1 - 0.0036 17.6 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OEU22201.1 - 0.0047 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OEU22201.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OEU22201.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OEU22201.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 OEU22202.1 - 5.3e-54 182.1 1.0 5.9e-54 182.0 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OEU22202.1 - 0.00017 22.2 1.1 0.0002 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OEU22202.1 - 0.00076 19.6 0.3 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OEU22202.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OEU22202.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OEU22202.1 - 0.045 13.8 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.7 OEU22203.1 - 3.3e-12 46.8 0.0 1.8e-11 44.5 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU22203.1 - 4e-09 36.8 0.2 2.1e-06 28.2 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22203.1 - 5.8e-07 29.3 0.0 0.0015 18.8 0.0 4.0 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OEU22203.1 - 2.4e-06 27.7 0.1 0.00051 20.3 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU22203.1 - 6.9e-05 23.1 0.0 0.065 13.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Acetyltransf_10 PF13673.7 OEU22204.1 - 0.0019 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU22204.1 - 0.0021 18.4 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hat1_N PF10394.9 OEU22204.1 - 0.0024 18.1 0.1 0.35 11.1 0.0 3.0 3 0 0 3 3 3 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 OEU22204.1 - 0.018 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PIG-X PF08320.12 OEU22206.1 - 2.7e-07 30.7 0.8 2.1e-06 27.8 0.8 2.4 1 1 0 1 1 1 1 PIG-X / PBN1 MutS_V PF00488.21 OEU22207.1 - 1.9e-73 246.5 0.3 3.5e-73 245.7 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 OEU22207.1 - 2.2e-05 24.7 0.4 5.5e-05 23.4 0.4 1.7 1 1 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 OEU22207.1 - 0.0052 17.0 0.2 0.0088 16.3 0.2 1.4 1 0 0 1 1 1 1 MutS domain III Cep57_MT_bd PF06657.13 OEU22207.1 - 0.0084 16.5 2.0 0.26 11.8 0.1 2.4 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 AAA_22 PF13401.6 OEU22207.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain LcrG PF07216.12 OEU22207.1 - 0.13 12.2 0.7 0.34 10.8 0.7 1.7 1 0 0 1 1 1 0 LcrG protein KELK PF15796.5 OEU22207.1 - 0.3 11.6 2.1 5.1 7.6 0.2 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase JAKMIP_CC3 PF16034.5 OEU22207.1 - 4.3 7.2 7.1 1.7 8.6 0.5 2.3 1 1 1 2 2 2 0 JAKMIP CC3 domain Aldo_ket_red PF00248.21 OEU22208.1 - 8.3e-39 133.5 0.0 5.4e-38 130.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family PRP38 PF03371.15 OEU22210.1 - 1.3e-54 184.7 0.0 1.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Fimbrillin_C PF15495.6 OEU22212.1 - 0.72 10.3 0.0 0.72 10.3 0.0 2.5 4 0 0 4 4 4 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal TFIIB_C_1 PF18542.1 OEU22213.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 tRNA-synt_1b PF00579.25 OEU22214.1 - 5e-47 160.6 0.1 1.6e-42 145.8 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (W and Y) LRR_8 PF13855.6 OEU22215.1 - 7.5e-14 51.2 16.6 0.00029 20.5 0.4 5.1 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OEU22215.1 - 4.6e-11 42.8 9.3 0.26 11.8 0.0 6.6 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OEU22215.1 - 0.22 12.2 12.1 79 4.4 1.5 7.1 7 1 0 7 7 7 0 Leucine Rich Repeat TIP49 PF06068.13 OEU22216.1 - 2.9e-150 500.3 0.1 3.6e-150 500.0 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OEU22216.1 - 2.2e-22 78.9 0.1 7.1e-22 77.3 0.0 2.0 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 OEU22216.1 - 1.5e-10 41.6 0.2 1e-06 29.2 0.0 2.8 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OEU22216.1 - 3.6e-08 33.8 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 OEU22216.1 - 5e-08 32.9 0.7 2.7e-05 23.9 0.0 3.0 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OEU22216.1 - 2.7e-05 24.6 0.1 0.00014 22.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OEU22216.1 - 3.5e-05 23.8 0.1 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OEU22216.1 - 4.1e-05 23.1 0.3 0.0016 17.9 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OEU22216.1 - 0.00016 22.0 0.2 0.0042 17.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU22216.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 OEU22216.1 - 0.00076 19.1 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OEU22216.1 - 0.00091 18.8 0.2 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 OEU22216.1 - 0.0029 17.8 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OEU22216.1 - 0.0035 17.9 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 ABC transporter Sigma54_activat PF00158.26 OEU22216.1 - 0.0039 16.9 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 OEU22216.1 - 0.0043 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 OEU22216.1 - 0.0074 16.7 0.0 0.022 15.1 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_30 PF13604.6 OEU22216.1 - 0.011 15.5 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 OEU22216.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 OEU22216.1 - 0.014 15.7 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OEU22216.1 - 0.037 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OEU22216.1 - 0.038 14.0 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 OEU22216.1 - 0.048 13.1 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein ResIII PF04851.15 OEU22216.1 - 0.068 13.2 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 OEU22216.1 - 0.084 12.0 0.0 8.1 5.5 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase DNA_pol3_delta2 PF13177.6 OEU22216.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_17 PF13207.6 OEU22216.1 - 0.094 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OEU22216.1 - 0.099 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OEU22216.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 OEU22216.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 OEU22216.1 - 0.16 12.0 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.24 OEU22218.1 - 1.9e-38 132.5 13.9 5.1e-38 131.1 13.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OEU22218.1 - 1.9e-22 79.7 28.9 3.7e-22 78.8 28.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OEU22218.1 - 0.00016 20.3 3.0 0.00025 19.6 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2_11 PF16622.5 OEU22218.1 - 0.18 11.6 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Pkinase PF00069.25 OEU22219.1 - 8.7e-36 123.6 0.0 1.1e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22219.1 - 7.3e-13 48.4 0.0 5.6e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU22219.1 - 1.5e-06 28.3 0.1 2.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OEU22219.1 - 0.00022 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OEU22219.1 - 0.039 12.7 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OEU22219.1 - 0.055 12.8 0.0 0.098 12.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OEU22219.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HNOB PF07700.15 OEU22220.1 - 5.6e-36 124.0 0.0 8.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding UPA PF17217.3 OEU22220.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 UPA domain Response_reg PF00072.24 OEU22221.1 - 2.3e-25 88.9 0.4 4.1e-25 88.1 0.4 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OEU22221.1 - 1.1e-24 87.1 0.5 5e-24 85.0 0.1 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OEU22221.1 - 8.3e-12 45.0 0.0 2.2e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OEU22221.1 - 4.1e-06 26.7 0.3 1e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAP PF07174.11 OEU22221.1 - 0.041 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) NIF PF03031.18 OEU22222.1 - 7.8e-55 184.9 0.4 1.1e-54 184.4 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF5523 PF17661.1 OEU22222.1 - 0.24 11.1 5.0 0.36 10.5 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ank_5 PF13857.6 OEU22224.1 - 1e-05 25.7 0.1 3.5e-05 24.0 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU22224.1 - 0.0005 20.6 0.0 0.0014 19.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU22224.1 - 0.0033 18.0 0.0 0.0069 17.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Fez1 PF06818.15 OEU22224.1 - 0.0096 16.4 19.1 0.0096 16.4 19.1 4.3 2 1 1 4 4 4 1 Fez1 DUF1664 PF07889.12 OEU22224.1 - 0.17 12.0 33.8 0.99 9.5 1.0 4.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Sacchrp_dh_NADP PF03435.18 OEU22224.1 - 8.6 6.6 8.9 0.54 10.5 0.7 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain OTU PF02338.19 OEU22225.1 - 1.5e-19 70.7 1.1 2.2e-19 70.2 0.1 1.8 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OEU22225.1 - 0.0001 21.9 5.2 0.51 9.7 0.1 3.0 1 1 2 3 3 3 3 Peptidase C65 Otubain SR-25 PF10500.9 OEU22225.1 - 0.012 15.3 3.2 0.015 14.9 3.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HR1 PF02185.16 OEU22226.1 - 0.029 14.5 0.9 0.054 13.6 0.9 1.5 1 0 0 1 1 1 0 Hr1 repeat Cir_N PF10197.9 OEU22226.1 - 0.043 14.0 3.9 0.12 12.6 3.9 1.7 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Uds1 PF15456.6 OEU22226.1 - 0.063 13.4 2.5 0.12 12.5 2.5 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF4407 PF14362.6 OEU22226.1 - 0.23 10.8 0.6 0.32 10.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kinesin PF00225.23 OEU22227.1 - 6.6e-32 110.7 0.0 7.4e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU22227.1 - 5.6e-07 29.6 0.1 0.00069 19.6 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding DOT1 PF08123.13 OEU22228.1 - 3.9e-06 26.5 0.0 8.1e-06 25.5 0.0 1.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 OEU22228.1 - 0.17 11.6 0.0 25 4.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Cpn60_TCP1 PF00118.24 OEU22229.1 - 2.2e-143 478.5 10.0 2.5e-143 478.3 10.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA_anti-codon PF01336.25 OEU22230.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain YabA PF06156.13 OEU22230.1 - 0.12 13.0 2.7 0.3 11.8 2.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA TMEM237 PF15383.6 OEU22230.1 - 0.16 11.1 1.0 0.25 10.4 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 RNA_pol_Rbc25 PF08292.12 OEU22230.1 - 0.26 11.5 1.4 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Pkinase PF00069.25 OEU22231.1 - 8.2e-37 127.0 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 OEU22231.1 - 2.8e-31 108.3 0.0 5.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 OEU22231.1 - 1.2e-17 64.1 0.0 2.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU22231.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU22231.1 - 0.094 11.5 0.2 1 8.0 0.2 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF3232 PF11554.8 OEU22232.1 - 0.0032 17.8 2.1 0.0042 17.5 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3232) DUF3492 PF11997.8 OEU22232.1 - 0.032 14.0 0.1 0.035 13.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) C_LFY_FLO PF17538.2 OEU22232.1 - 0.081 12.4 0.3 0.17 11.3 0.2 1.5 1 1 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula SUIM_assoc PF16619.5 OEU22232.1 - 0.12 12.5 0.3 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1664 PF07889.12 OEU22232.1 - 0.2 11.7 2.0 7.5 6.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Aminotran_1_2 PF00155.21 OEU22233.1 - 2e-32 112.7 0.0 9.1e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 OEU22233.1 - 0.001 18.0 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Allinase GDP_Man_Dehyd PF16363.5 OEU22234.1 - 2.3e-60 204.8 0.0 9.3e-60 202.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU22234.1 - 2e-53 181.3 0.0 2.5e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU22234.1 - 5.9e-20 71.4 0.0 8.4e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU22234.1 - 7.4e-17 61.4 0.0 7.5e-16 58.1 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU22234.1 - 4.1e-11 42.5 0.0 6.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OEU22234.1 - 9.5e-09 34.8 0.0 1.7e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OEU22234.1 - 6.7e-06 26.1 0.1 0.00012 22.1 0.1 2.4 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 OEU22234.1 - 4.1e-05 23.5 0.0 0.00018 21.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OEU22234.1 - 4.6e-05 23.0 0.0 0.00035 20.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 OEU22234.1 - 0.0026 18.0 0.1 0.02 15.1 0.1 2.2 1 1 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 OEU22234.1 - 0.0071 15.9 0.0 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Pyr_redox_2 PF07992.14 OEU22234.1 - 0.035 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU22234.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YrbL-PhoP_reg PF10707.9 OEU22234.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Sacchrp_dh_NADP PF03435.18 OEU22234.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NFACT-R_1 PF05670.13 OEU22235.1 - 3.8e-07 30.7 0.0 1.3e-05 25.8 0.0 2.5 2 1 1 3 3 3 1 NFACT protein RNA binding domain FbpA PF05833.11 OEU22235.1 - 1.7e-06 27.1 0.0 1.7e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_2 PF18297.1 OEU22235.1 - 2.4e-06 27.7 0.0 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain GST_C PF00043.25 OEU22236.1 - 6.8e-07 29.4 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU22236.1 - 0.00018 21.8 0.0 0.00049 20.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OEU22236.1 - 0.00039 20.8 0.0 0.0007 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OEU22236.1 - 0.0023 17.9 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OEU22236.1 - 0.0047 17.1 0.1 0.0065 16.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OEU22236.1 - 0.045 14.0 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OEU22236.1 - 0.08 13.7 0.0 0.2 12.4 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N_5 PF18485.1 OEU22236.1 - 0.091 13.1 0.0 0.21 12.0 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PGP_phosphatase PF09419.10 OEU22236.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase VKOR PF07884.14 OEU22238.1 - 2e-16 60.3 6.3 2.5e-16 60.0 6.3 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family XRN_N PF03159.18 OEU22239.1 - 3.2e-79 265.8 0.0 4.2e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus TFIIA PF03153.13 OEU22242.1 - 0.14 12.2 7.2 0.15 12.0 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.21 OEU22243.1 - 1e-61 208.7 0.0 1.3e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OEU22243.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Ank_5 PF13857.6 OEU22246.1 - 7.8e-08 32.4 0.0 0.00022 21.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU22246.1 - 1.2e-07 32.1 0.0 4.5e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU22246.1 - 1.7e-05 25.3 0.0 0.0043 17.6 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22246.1 - 0.0029 18.0 0.0 0.37 11.5 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OEU22246.1 - 0.007 16.8 0.0 2.4 8.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat WD40 PF00400.32 OEU22247.1 - 7.1e-45 150.1 14.1 5.6e-07 30.2 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22247.1 - 2.4e-08 34.1 0.5 0.071 13.4 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OEU22247.1 - 0.0024 17.9 0.2 0.31 11.1 0.0 3.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 OEU22247.1 - 0.014 14.1 12.6 4.9 5.7 0.0 5.6 4 3 2 6 6 6 0 Nucleoporin Nup120/160 EIIBC-GUT_N PF03612.14 OEU22248.1 - 0.53 10.0 7.9 2 8.1 0.5 3.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.10 OEU22248.1 - 2 8.5 15.7 0.69 10.0 2.9 3.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal FKBP_C PF00254.28 OEU22249.1 - 5.1e-13 49.2 0.0 6.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DMRL_synthase PF00885.19 OEU22250.1 - 2.1e-47 160.5 0.0 2.3e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ABC1 PF03109.16 OEU22251.1 - 5.5e-29 100.8 0.0 1.4e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family FCD PF07729.12 OEU22251.1 - 0.069 13.6 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 FCD domain Mito_carr PF00153.27 OEU22252.1 - 1.7e-49 165.7 2.4 1e-16 60.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cullin PF00888.22 OEU22253.1 - 7.4e-34 117.3 0.6 9.3e-34 117.0 0.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 OEU22253.1 - 1.3e-21 76.4 1.3 1.3e-21 76.4 1.3 2.0 3 0 0 3 3 3 1 Cullin protein neddylation domain NMO PF03060.15 OEU22253.1 - 0.22 10.9 0.6 0.34 10.3 0.3 1.3 1 1 0 1 1 1 0 Nitronate monooxygenase Motile_Sperm PF00635.26 OEU22254.1 - 2.3e-13 50.0 0.0 4.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Filament PF00038.21 OEU22254.1 - 0.017 14.7 0.4 0.024 14.3 0.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein RhlB PF12300.8 OEU22254.1 - 1.6 8.8 5.4 3.6 7.7 5.4 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB LRR_6 PF13516.6 OEU22255.1 - 1.1e-10 40.7 10.8 0.024 14.7 0.0 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 OEU22255.1 - 9.2e-06 25.9 5.9 2.5 8.7 0.1 5.6 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU22255.1 - 0.00016 21.4 3.9 0.88 9.4 0.0 5.4 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 OEU22255.1 - 0.00067 19.9 2.5 70 4.6 0.0 5.9 5 2 0 5 5 5 0 Leucine Rich Repeat CBP4 PF07960.11 OEU22256.1 - 0.046 13.6 0.1 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 CBP4 AhpC-TSA PF00578.21 OEU22258.1 - 1.6e-09 37.7 0.6 4.5e-09 36.3 0.6 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OEU22258.1 - 2.8e-08 34.0 0.1 4.6e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU22258.1 - 3.7e-08 33.2 0.2 4.9e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 OEU22258.1 - 0.006 16.6 0.9 0.0091 16.0 0.5 1.5 2 0 0 2 2 2 1 Thioredoxin GCIP PF13324.6 OEU22258.1 - 0.1 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Thioredoxin_2 PF13098.6 OEU22258.1 - 0.13 12.8 1.0 0.26 11.7 1.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain ECH_2 PF16113.5 OEU22259.1 - 8.6e-22 78.1 0.0 6.6e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase MIase PF02426.16 OEU22259.1 - 0.16 12.2 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Muconolactone delta-isomerase DEK_C PF08766.11 OEU22260.1 - 2e-09 37.2 0.0 6.3e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 OEU22260.1 - 0.097 12.5 0.1 2.2 8.2 0.1 2.6 1 1 0 1 1 1 0 SAP domain SnAC PF14619.6 OEU22260.1 - 0.21 12.2 5.6 0.47 11.1 1.9 2.5 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex bMG5 PF17972.1 OEU22261.1 - 0.021 15.2 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain Ydr279_N PF17745.1 OEU22262.1 - 0.059 13.6 0.2 2 8.7 0.2 2.3 1 1 0 1 1 1 0 Ydr279p protein triple barrel domain RRM_1 PF00076.22 OEU22263.1 - 1.6e-18 66.3 0.0 1.8e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OEU22263.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_occluded PF16842.5 OEU22263.1 - 0.028 14.3 0.0 0.097 12.5 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Aldedh PF00171.22 OEU22264.1 - 8.8e-70 235.5 0.0 1.1e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OEU22264.1 - 0.0046 16.1 0.0 0.015 14.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Unstab_antitox PF09720.10 OEU22264.1 - 0.0048 16.9 0.9 0.64 10.1 0.5 2.6 2 0 0 2 2 2 2 Putative addiction module component F_bP_aldolase PF01116.20 OEU22265.1 - 1.2e-91 307.1 0.0 1.4e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II GIDA PF01134.22 OEU22266.1 - 7.5e-94 315.0 0.0 1.2e-93 314.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OEU22266.1 - 3.1e-63 213.8 0.2 4.6e-63 213.2 0.2 1.3 1 0 0 1 1 1 1 GidA associated domain GIDA PF01134.22 OEU22267.1 - 1.8e-31 109.6 5.3 2.1e-31 109.4 5.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OEU22267.1 - 2.6e-07 30.3 2.2 2.9e-07 30.2 2.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU22267.1 - 7e-07 28.7 2.8 8.2e-07 28.4 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OEU22267.1 - 1.9e-06 27.3 0.5 2.1e-06 27.2 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OEU22267.1 - 0.00017 21.0 1.4 0.00021 20.7 1.0 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OEU22267.1 - 0.00057 20.4 0.3 0.00077 20.0 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU22267.1 - 0.0014 17.9 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU22267.1 - 0.0031 16.8 0.2 0.0037 16.5 0.2 1.1 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OEU22267.1 - 0.0082 14.9 0.7 0.01 14.6 0.7 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OEU22267.1 - 0.0088 15.3 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OEU22267.1 - 0.041 13.5 0.6 0.051 13.2 0.6 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase DJ-1_PfpI PF01965.24 OEU22267.1 - 0.057 13.2 0.2 0.094 12.5 0.1 1.4 1 1 0 1 1 1 0 DJ-1/PfpI family Lycopene_cycl PF05834.12 OEU22267.1 - 0.066 12.3 1.3 0.083 11.9 1.3 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OEU22267.1 - 0.077 11.8 0.1 0.092 11.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 OEU22267.1 - 0.083 13.1 1.5 0.12 12.6 1.5 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OEU22267.1 - 0.14 12.6 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DnaJ PF00226.31 OEU22268.1 - 7.2e-12 45.3 0.1 1.5e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OEU22269.1 - 3.2e-36 124.7 0.2 5.6e-36 123.8 0.2 1.4 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OEU22269.1 - 7.6e-21 74.0 1.7 7.6e-21 74.0 1.7 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OEU22269.1 - 9.1e-08 32.4 3.0 1.9e-07 31.3 3.0 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 OEU22269.1 - 1.7 8.9 5.8 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5351) ThiS PF02597.20 OEU22271.1 - 7e-15 55.4 0.0 8e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 ThiS family ATP-synt_C PF00137.21 OEU22272.1 - 1.4e-34 118.2 37.3 5.4e-23 81.1 16.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 OEU22272.1 - 7.6 6.7 6.7 3.3 7.8 2.6 2.3 2 0 0 2 2 2 0 Cell division protein CrgA Adaptin_N PF01602.20 OEU22273.1 - 1.1e-66 225.5 3.0 1.8e-65 221.5 2.1 2.3 2 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 OEU22273.1 - 2.1e-17 63.6 1.6 6.4e-17 62.1 1.6 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OEU22273.1 - 1e-07 31.6 0.5 0.019 15.2 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 OEU22273.1 - 7.7e-05 23.0 0.4 0.028 14.8 0.1 3.6 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 OEU22273.1 - 0.0015 19.0 0.8 2.3 8.8 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat Vitellogenin_N PF01347.22 OEU22273.1 - 0.0092 14.4 0.1 0.02 13.3 0.1 1.5 1 0 0 1 1 1 1 Lipoprotein amino terminal region Astro_capsid_p PF12226.8 OEU22273.1 - 8.3 5.5 11.4 20 4.2 11.4 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ribosomal_L34 PF00468.17 OEU22274.1 - 3e-16 59.1 12.5 5e-16 58.4 12.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M22 PF00814.25 OEU22275.1 - 1.7e-81 273.9 0.0 2.2e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OEU22275.1 - 0.041 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus RibD_C PF01872.17 OEU22276.1 - 5.4e-24 85.1 0.1 1.6e-23 83.6 0.1 1.8 1 1 1 2 2 2 1 RibD C-terminal domain EF-hand_1 PF00036.32 OEU22277.1 - 4.4e-38 126.0 19.2 1e-09 37.2 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OEU22277.1 - 7.9e-33 112.7 10.3 1.6e-16 60.5 3.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OEU22277.1 - 9.6e-33 111.8 18.3 2.6e-15 56.0 1.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OEU22277.1 - 2.9e-29 98.4 13.5 2.7e-09 36.2 0.3 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OEU22277.1 - 6.1e-27 91.9 17.6 2.2e-07 30.0 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OEU22277.1 - 6.9e-13 48.7 0.3 1.5e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OEU22277.1 - 9.7e-10 38.8 0.2 0.00076 19.8 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OEU22277.1 - 2.2e-08 34.2 1.0 0.00068 19.8 0.2 2.4 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_4 PF12763.7 OEU22277.1 - 9e-08 32.0 5.4 0.0011 18.9 0.3 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 OEU22277.1 - 6.3e-05 23.0 1.0 0.0079 16.2 0.1 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_11 PF08976.11 OEU22277.1 - 0.00012 22.9 0.1 0.0017 19.2 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 OEU22277.1 - 0.00026 20.7 4.0 0.00032 20.4 4.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.16 OEU22277.1 - 0.00093 19.5 0.9 0.44 10.9 0.1 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb4 UPF0154 PF03672.13 OEU22277.1 - 0.0013 18.7 0.0 2.5 8.2 0.0 2.8 3 0 0 3 3 2 2 Uncharacterised protein family (UPF0154) DUF1296 PF06972.11 OEU22277.1 - 0.0017 18.4 0.9 0.73 10.0 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) DUF1456 PF07308.13 OEU22277.1 - 0.0022 18.3 1.1 0.2 12.0 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1456) EFhand_Ca_insen PF08726.10 OEU22277.1 - 0.0027 17.8 3.2 0.0041 17.2 0.2 2.6 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF533 PF04391.12 OEU22277.1 - 0.0058 16.2 4.1 0.26 10.8 1.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF533) SurA_N_2 PF13623.6 OEU22277.1 - 0.0089 15.9 1.9 0.2 11.5 0.5 2.4 1 1 1 2 2 2 1 SurA N-terminal domain Caleosin PF05042.13 OEU22277.1 - 0.015 15.3 4.6 8.9 6.2 0.0 3.7 1 1 3 4 4 4 0 Caleosin related protein Syntaxin PF00804.25 OEU22277.1 - 0.024 14.3 2.3 3.4 7.3 0.1 2.2 1 1 1 2 2 2 0 Syntaxin DUF5580 PF17743.1 OEU22277.1 - 0.031 12.8 0.0 0.034 12.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RTX_C PF08339.10 OEU22277.1 - 0.035 14.2 1.4 0.23 11.5 0.3 2.0 1 1 1 2 2 2 0 RTX C-terminal domain PMBR PF09373.10 OEU22277.1 - 0.038 14.1 0.2 49 4.3 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat TetR_C_7 PF14246.6 OEU22277.1 - 0.043 13.8 0.0 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Phage_TAC_12 PF12363.8 OEU22277.1 - 0.11 12.9 1.0 7.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC GlutR_dimer PF00745.20 OEU22277.1 - 0.13 12.7 0.8 16 6.0 0.1 2.6 2 2 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain FDX-ACB PF03147.14 OEU22277.1 - 0.17 12.3 0.7 12 6.3 0.1 2.6 1 1 0 2 2 2 0 Ferredoxin-fold anticodon binding domain VbhA PF18495.1 OEU22277.1 - 0.19 11.6 1.6 13 5.7 0.0 3.5 4 1 0 4 4 4 0 Antitoxin VbhA SapB_1 PF05184.15 OEU22277.1 - 0.42 10.7 4.3 34 4.6 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 TRAM_LAG1_CLN8 PF03798.16 OEU22278.1 - 2.8e-12 46.8 15.2 8.6e-12 45.2 15.2 1.7 1 1 0 1 1 1 1 TLC domain RRM_1 PF00076.22 OEU22279.1 - 4.1e-15 55.4 2.4 4.8e-13 48.7 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 OEU22279.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 OEU22279.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ATP-synt_C PF00137.21 OEU22281.1 - 1.4e-34 118.2 37.3 5.4e-23 81.1 16.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 OEU22281.1 - 4.8 7.3 6.2 2.6 8.2 2.3 2.3 2 0 0 2 2 2 0 Cell division protein CrgA AAA PF00004.29 OEU22282.1 - 3.1e-12 47.0 0.0 6.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU22282.1 - 1.3e-08 35.4 0.0 5.9e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 OEU22282.1 - 1e-06 28.8 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 OEU22282.1 - 8.9e-06 26.0 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Med26 PF08711.11 OEU22286.1 - 4e-07 30.0 0.5 4e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain ATP-synt_C PF00137.21 OEU22287.1 - 5.2e-29 100.4 27.6 7.9e-16 58.2 8.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PEP_hydrolase PF09370.10 OEU22287.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like HOOK PF05622.12 OEU22288.1 - 3.4e-43 147.8 53.7 8.4e-24 83.7 0.0 4.1 2 1 2 4 4 4 3 HOOK protein DUF4164 PF13747.6 OEU22288.1 - 0.018 15.3 13.5 0.018 15.3 13.5 5.4 3 2 3 6 6 6 0 Domain of unknown function (DUF4164) DUF1499 PF07386.11 OEU22288.1 - 1.8 9.2 6.5 0.2 12.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1499) Baculo_PEP_C PF04513.12 OEU22288.1 - 4.9 7.2 21.8 0.17 11.9 3.3 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 OEU22288.1 - 6.3 7.2 52.8 0.027 14.9 22.8 3.6 1 1 1 2 2 2 0 Fez1 PLAC9 PF15205.6 OEU22289.1 - 0.52 10.7 3.4 0.68 10.4 2.8 1.6 1 1 0 1 1 1 0 Placenta-specific protein 9 DUF1542 PF07564.11 OEU22289.1 - 0.71 10.0 6.0 4.2 7.5 0.9 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) SMYLE_N PF18615.1 OEU22289.1 - 1.4 8.4 6.6 1.6 8.2 6.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DsbD PF02683.15 OEU22290.1 - 8.4e-33 114.1 4.7 8.4e-33 114.1 4.7 1.5 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Peptidase_S9 PF00326.21 OEU22291.1 - 3.4e-38 131.3 0.0 4.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OEU22291.1 - 1.2e-08 35.0 0.1 8.9e-05 22.2 0.3 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OEU22291.1 - 2.7e-05 23.0 0.0 0.003 16.3 0.0 2.0 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 OEU22291.1 - 5.2e-05 22.6 0.0 0.0071 15.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OEU22291.1 - 0.00024 20.7 0.0 0.013 15.1 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OEU22291.1 - 0.00042 20.2 0.0 0.00094 19.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OEU22291.1 - 0.0068 16.4 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 OEU22291.1 - 0.018 14.6 0.0 0.91 9.1 0.0 2.2 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 OEU22291.1 - 0.019 14.6 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OEU22291.1 - 0.037 14.6 0.2 0.037 14.6 0.2 1.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 OEU22291.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Esterase_phd PF10503.9 OEU22291.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S28 PF05577.12 OEU22291.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RNA_binding PF01877.17 OEU22292.1 - 0.21 11.9 1.6 0.44 10.8 0.5 2.1 3 0 0 3 3 3 0 RNA binding Poty_PP PF08440.10 OEU22292.1 - 0.23 10.5 4.1 3.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Potyviridae polyprotein BET PF17035.5 OEU22292.1 - 0.27 11.4 8.2 2.5 8.3 0.3 3.1 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation DUF1932 PF09130.11 OEU22292.1 - 1.6 8.7 4.7 2.5 8.2 0.2 3.4 4 1 1 5 5 5 0 Domain of unknown function (DUF1932) Nebulin PF00880.18 OEU22292.1 - 7.3 6.6 8.7 6.9 6.7 0.1 3.4 3 1 0 3 3 3 0 Nebulin repeat Phasin PF05597.11 OEU22292.1 - 8.8 6.3 12.7 23 5.0 0.1 3.4 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NUDIX PF00293.28 OEU22293.1 - 1.6e-16 60.6 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 OEU22293.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) MBD PF01429.19 OEU22294.1 - 1.4e-05 24.7 0.3 4.3e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 Methyl-CpG binding domain DUF5319 PF17252.2 OEU22295.1 - 0.0027 17.9 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5319) WD40 PF00400.32 OEU22296.1 - 6.6e-10 39.4 7.2 0.016 16.1 1.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22296.1 - 0.079 13.3 0.0 5.6 7.3 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain S10_plectin PF03501.15 OEU22297.1 - 5.7e-38 128.9 0.1 6.7e-38 128.7 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_13 PF17958.1 OEU22298.1 - 2.3e-33 113.9 0.2 2.3e-32 110.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OEU22298.1 - 7.9e-16 58.3 7.9 2.2e-13 50.4 5.1 4.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OEU22298.1 - 3.5e-05 23.1 0.4 0.0011 18.4 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 OEU22298.1 - 5.2e-05 22.5 0.2 0.021 14.3 0.0 4.2 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 OEU22298.1 - 0.00016 21.3 0.1 0.57 10.3 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OEU22298.1 - 0.049 13.5 2.9 1 9.3 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain pair EMP70 PF02990.16 OEU22299.1 - 7.9e-191 635.2 7.2 9.8e-191 634.9 7.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 FtsL PF04999.13 OEU22299.1 - 0.27 11.2 2.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsL Acetyltransf_1 PF00583.25 OEU22300.1 - 6e-12 45.8 0.0 8.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OEU22300.1 - 4.4e-10 39.6 0.1 6.2e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OEU22300.1 - 3.1e-09 36.7 0.0 5.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OEU22300.1 - 7.8e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU22300.1 - 0.00037 20.6 0.0 0.00083 19.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU22300.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 OEU22300.1 - 0.098 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase ArfGap PF01412.18 OEU22302.1 - 3.2e-33 114.3 0.4 1.2e-32 112.4 0.4 1.7 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1279 PF06916.13 OEU22303.1 - 8.7e-22 77.5 0.1 1.9e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) DUF4064 PF13273.6 OEU22303.1 - 0.047 14.0 0.1 0.11 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2062 PF09835.9 OEU22303.1 - 0.2 11.5 0.8 0.85 9.5 0.3 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DPM3 PF08285.11 OEU22304.1 - 1.8e-19 69.7 0.0 2e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PP2C PF00481.21 OEU22305.1 - 9.6e-47 159.8 0.0 1.2e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OEU22305.1 - 1.4e-08 34.9 0.0 3.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OEU22305.1 - 0.00075 19.2 0.1 0.059 13.0 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C UPF0181 PF03701.14 OEU22305.1 - 0.074 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Polbeta PF18765.1 OEU22309.1 - 0.019 15.0 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase CsgF PF10614.9 OEU22309.1 - 0.056 13.7 0.0 0.056 13.7 0.0 1.9 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein ArfGap PF01412.18 OEU22310.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CKS PF01111.19 OEU22310.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit Trypsin PF00089.26 OEU22311.1 - 4.8e-45 154.1 0.0 7e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU22311.1 - 6.3e-07 30.4 0.0 9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DNA_ligase_A_M PF01068.21 OEU22312.1 - 1.1e-27 97.0 0.0 2.3e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 OEU22312.1 - 3e-15 56.6 0.0 5.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region LRR_6 PF13516.6 OEU22314.1 - 7.3e-14 50.6 8.5 0.00057 19.7 0.1 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 OEU22314.1 - 9e-07 29.1 4.4 0.23 11.9 0.0 5.3 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU22314.1 - 0.00036 20.2 0.4 3.8 7.3 0.0 5.0 5 2 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.33 OEU22314.1 - 0.00052 20.2 3.8 8.7 7.3 0.0 6.5 7 0 0 7 7 7 1 Leucine Rich Repeat MGS PF02142.22 OEU22315.1 - 0.12 12.5 0.0 3.7 7.8 0.0 2.3 2 0 0 2 2 2 0 MGS-like domain Spc7 PF08317.11 OEU22316.1 - 0.006 15.5 3.2 0.0089 14.9 3.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 OEU22316.1 - 0.0064 16.1 6.3 0.0082 15.7 6.3 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 CENP-H PF05837.12 OEU22316.1 - 0.012 16.0 3.1 0.019 15.4 3.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3941 PF13081.6 OEU22316.1 - 0.029 14.7 0.2 0.065 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3941) MAT1 PF06391.13 OEU22316.1 - 0.062 13.1 4.6 0.08 12.8 4.6 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 KAR9 PF08580.10 OEU22316.1 - 0.12 10.9 3.7 0.15 10.6 3.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF4559 PF15112.6 OEU22316.1 - 0.3 10.7 4.3 0.4 10.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) eIF-4B PF06273.11 OEU22316.1 - 0.74 8.8 5.0 0.95 8.4 5.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF1664 PF07889.12 OEU22316.1 - 3.2 7.8 6.2 2 8.5 1.6 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HCNGP PF07818.13 OEU22317.1 - 3.4e-05 24.4 1.4 3.6e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 HCNGP-like protein PX PF00787.24 OEU22318.1 - 1e-20 73.8 0.1 1e-20 73.8 0.1 2.4 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 OEU22318.1 - 0.00074 19.1 8.7 0.00074 19.1 8.7 1.6 2 0 0 2 2 2 1 Vps5 C terminal like DUF4518 PF15008.6 OEU22318.1 - 0.023 13.9 3.7 0.68 9.1 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4518) Nup54 PF13874.6 OEU22318.1 - 0.64 10.1 6.0 2 8.6 1.8 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FKBP_C PF00254.28 OEU22319.1 - 0.00013 22.2 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF334 PF03904.13 OEU22319.1 - 0.003 17.1 0.2 0.0064 16.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF334) TPR_1 PF00515.28 OEU22319.1 - 0.065 13.1 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fer4 PF00037.27 OEU22320.1 - 5.9e-14 51.2 15.7 2e-08 33.7 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OEU22320.1 - 3.2e-13 50.0 10.5 5.7e-13 49.2 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OEU22320.1 - 4.5e-11 43.5 5.7 3.3e-05 24.7 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 OEU22320.1 - 4.5e-09 36.3 21.0 9.1e-07 28.9 12.2 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 OEU22320.1 - 9.6e-09 35.3 32.3 7.6e-06 26.0 12.6 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 OEU22320.1 - 1.5e-08 34.6 10.6 2.7e-08 33.9 10.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OEU22320.1 - 1.7e-07 31.0 17.1 0.00017 21.5 4.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 OEU22320.1 - 1.9e-07 31.4 17.8 0.00014 22.2 11.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OEU22320.1 - 4.1e-06 26.6 12.2 0.0031 17.5 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OEU22320.1 - 1e-05 25.6 11.1 0.00043 20.6 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OEU22320.1 - 0.00059 20.3 11.8 0.033 14.7 12.6 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 OEU22320.1 - 0.017 15.7 14.4 0.66 10.6 4.1 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OEU22320.1 - 0.019 15.2 5.4 0.89 9.8 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OEU22320.1 - 0.06 13.5 8.6 1.6 8.9 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 OEU22320.1 - 0.1 13.6 15.8 0.4 11.7 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 OEU22320.1 - 0.48 10.6 6.7 2.2 8.5 0.9 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 OEU22320.1 - 0.66 10.9 12.0 3.4 8.6 1.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain bZIP_1 PF00170.21 OEU22321.1 - 3e-10 40.0 6.4 8.4e-10 38.6 6.4 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU22321.1 - 2.3e-06 27.6 4.5 7.6e-06 25.9 4.5 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU22321.1 - 0.29 11.7 10.4 0.033 14.7 5.1 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40 PF00400.32 OEU22322.1 - 2.3e-26 91.5 10.3 9.9e-09 35.7 0.1 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22322.1 - 1.4e-10 41.3 0.0 0.25 11.7 0.0 5.8 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OEU22322.1 - 6.2e-06 25.1 0.1 0.19 10.3 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OEU22322.1 - 0.0021 18.5 3.3 29 5.3 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain PQQ PF01011.21 OEU22322.1 - 0.0049 16.7 0.0 4.7 7.3 0.0 3.3 2 0 0 2 2 2 2 PQQ enzyme repeat PALB2_WD40 PF16756.5 OEU22322.1 - 0.022 13.7 0.1 14 4.5 0.0 3.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 OEU22322.1 - 0.075 12.9 0.0 2.8 7.8 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OEU22322.1 - 0.18 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Methyltransf_11 PF08241.12 OEU22323.1 - 4.7e-15 56.0 0.0 6.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU22323.1 - 9.2e-13 48.7 0.0 2.1e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU22323.1 - 1.4e-12 47.7 0.1 1.6e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU22323.1 - 3.6e-06 26.9 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU22323.1 - 8.3e-06 26.5 0.0 1.3e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU22323.1 - 0.0066 15.8 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OEU22323.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain FAM91_C PF14648.6 OEU22323.1 - 0.036 12.9 0.0 0.039 12.8 0.0 1.0 1 0 0 1 1 1 0 FAM91 C-terminus TPMT PF05724.11 OEU22323.1 - 0.052 13.2 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.16 OEU22323.1 - 0.092 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Mur_ligase_C PF02875.21 OEU22324.1 - 3.8e-06 27.1 0.0 1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 OEU22324.1 - 4e-06 26.9 0.0 1e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_31 PF13847.6 OEU22325.1 - 6e-13 48.9 0.0 8.6e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OEU22325.1 - 2.2e-11 44.3 0.1 5e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU22325.1 - 6e-11 42.8 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU22325.1 - 1.7e-07 30.8 0.0 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OEU22325.1 - 0.0039 17.9 0.0 0.0082 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ERF PF04404.12 OEU22325.1 - 0.014 15.2 0.1 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 ERF superfamily DUF573 PF04504.14 OEU22326.1 - 0.054 14.2 6.9 0.36 11.5 0.8 2.7 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Tropomyosin PF00261.20 OEU22326.1 - 0.055 12.8 34.6 0.033 13.5 21.6 2.2 2 0 0 2 2 2 0 Tropomyosin Nbs1_C PF08599.10 OEU22326.1 - 0.49 10.6 3.1 0.45 10.7 0.2 2.4 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 PilJ PF13675.6 OEU22326.1 - 0.68 10.0 7.0 0.26 11.3 0.5 2.6 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Leu_zip PF15294.6 OEU22326.1 - 0.76 9.2 32.5 0.36 10.3 9.7 2.2 1 1 1 2 2 2 0 Leucine zipper DUF1492 PF07374.11 OEU22326.1 - 0.87 9.8 12.0 0.75 10.0 2.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) TraC PF07820.12 OEU22326.1 - 0.96 9.8 5.1 1.6 9.1 0.1 3.2 3 0 0 3 3 3 0 TraC-like protein Filament PF00038.21 OEU22326.1 - 1.1 8.7 31.9 4.9 6.7 31.9 2.1 1 1 0 1 1 1 0 Intermediate filament protein Syntaxin-6_N PF09177.11 OEU22326.1 - 2.7 8.6 17.4 0.15 12.7 3.9 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 OEU22326.1 - 3.8 7.6 32.7 1.9 8.6 12.3 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PBECR1 PF18809.1 OEU22326.1 - 7.7 7.2 8.3 24 5.7 0.1 2.9 1 1 2 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Peptidase_S26 PF10502.9 OEU22327.1 - 4.7e-13 49.1 0.0 7.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OEU22327.1 - 3.7e-12 46.0 0.2 1.3e-11 44.3 0.2 1.9 1 1 0 1 1 1 1 Peptidase S24-like MMR_HSR1 PF01926.23 OEU22328.1 - 2.8e-18 66.1 0.0 3.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU22328.1 - 2.3e-05 24.4 0.7 0.0045 16.9 0.0 2.5 3 0 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OEU22328.1 - 8.8e-05 22.1 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OEU22328.1 - 0.00011 22.3 0.3 0.0024 17.9 0.1 2.3 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 OEU22328.1 - 0.0028 17.2 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 OEU22328.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OEU22328.1 - 0.057 12.7 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 OEU22328.1 - 0.073 13.6 0.1 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OEU22328.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tegument_dsDNA PF12818.7 OEU22329.1 - 0.0078 15.4 0.0 1.9 7.5 0.0 2.4 2 1 0 2 2 2 2 dsDNA viral tegument protein PDGLE PF13190.6 OEU22329.1 - 0.46 10.4 5.9 4.1 7.4 0.0 3.5 4 0 0 4 4 4 0 PDGLE domain Curto_V3 PF07436.11 OEU22329.1 - 0.72 10.3 2.9 21 5.6 0.0 2.9 3 0 0 3 3 3 0 Curtovirus V3 protein BNIP3 PF06553.12 OEU22329.1 - 1.8 8.2 3.5 6.5 6.4 0.0 2.5 3 0 0 3 3 3 0 BNIP3 DUF3119 PF11317.8 OEU22330.1 - 8.8e-35 119.7 0.0 1.2e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) MutS_V PF00488.21 OEU22331.1 - 2.3e-27 96.2 0.0 5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V AAA_21 PF13304.6 OEU22331.1 - 5.1e-05 23.2 0.0 0.011 15.6 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MutS_III PF05192.18 OEU22331.1 - 0.0042 17.3 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain III Fasciclin PF02469.22 OEU22332.1 - 6.5e-28 97.5 0.0 7.6e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Fea1 PF07692.11 OEU22332.1 - 0.083 11.9 0.4 4.3 6.3 0.2 2.0 1 1 1 2 2 2 0 Low iron-inducible periplasmic protein Fasciclin PF02469.22 OEU22333.1 - 5.1e-34 117.2 0.1 1.5e-28 99.5 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 OEU22334.1 - 1.6e-32 112.4 0.1 4.6e-27 94.8 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 OEU22335.1 - 1.3e-28 99.8 0.0 1.5e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain tRNA_Me_trans PF03054.16 OEU22336.1 - 1.2e-81 274.3 0.0 1.8e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 OEU22336.1 - 9.4e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 OEU22336.1 - 2.8e-05 23.4 0.0 0.00012 21.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 OEU22336.1 - 0.036 13.8 0.1 0.076 12.8 0.1 1.6 1 1 0 1 1 1 0 PP-loop family SBF PF01758.16 OEU22337.1 - 8e-22 77.9 12.5 8e-22 77.9 12.5 2.3 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 OEU22337.1 - 3.7e-18 65.9 21.8 4.6e-18 65.6 21.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) PseudoU_synth_2 PF00849.22 OEU22338.1 - 7.7e-25 87.8 6.2 1e-13 51.7 0.5 4.0 3 1 0 3 3 3 2 RNA pseudouridylate synthase Mitofilin PF09731.9 OEU22338.1 - 0.46 9.2 5.5 0.11 11.4 1.1 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein SDA1 PF05285.12 OEU22338.1 - 9 5.6 19.3 0.041 13.3 5.0 2.9 2 1 1 3 3 3 0 SDA1 DAGK_acc PF00609.19 OEU22340.1 - 3.5e-45 154.2 0.0 5.4e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OEU22340.1 - 1.8e-22 79.3 0.0 4.1e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Smr PF01713.21 OEU22341.1 - 5.4e-05 23.5 0.1 0.0001 22.6 0.1 1.5 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 OEU22341.1 - 0.0019 18.2 5.8 0.0019 18.2 5.8 2.4 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 OEU22341.1 - 0.017 15.8 4.2 0.017 15.8 4.2 2.5 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 OEU22341.1 - 0.37 11.0 3.5 7.3 6.9 1.1 2.7 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 OEU22341.1 - 0.84 10.2 10.5 5.5 7.6 1.3 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 OEU22341.1 - 4.9 7.2 12.1 0.52 10.3 4.6 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Frag1 PF10277.9 OEU22342.1 - 0.2 11.2 11.6 0.044 13.3 5.4 2.1 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family DUF2621 PF11084.8 OEU22342.1 - 0.33 10.9 2.6 0.59 10.1 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) MgtE PF01769.16 OEU22342.1 - 0.45 10.9 7.6 0.7 10.3 7.4 1.5 1 1 0 1 1 1 0 Divalent cation transporter DUF805 PF05656.14 OEU22342.1 - 3.3 8.2 8.3 6.8 7.2 8.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4131 PF13567.6 OEU22342.1 - 3.5 7.2 6.8 14 5.3 2.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) STIMATE PF12400.8 OEU22343.1 - 6.3e-28 97.8 5.7 6.3e-28 97.8 5.7 1.6 2 0 0 2 2 2 1 STIMATE family PH PF00169.29 OEU22344.1 - 2.4e-13 50.5 0.7 1.1e-12 48.4 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OEU22344.1 - 0.052 14.0 0.1 0.44 11.0 0.1 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 OEU22344.1 - 0.069 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 PH domain SRC-1 PF08832.10 OEU22344.1 - 0.19 12.8 3.7 0.13 13.4 0.5 2.4 2 0 0 2 2 2 0 Steroid receptor coactivator ATG16 PF08614.11 OEU22344.1 - 0.19 11.9 19.0 0.15 12.3 8.6 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) YwqJ-deaminase PF14431.6 OEU22344.1 - 0.26 11.5 1.1 0.82 9.9 0.5 2.1 2 0 0 2 2 2 0 YwqJ-like deaminase FapA PF03961.13 OEU22344.1 - 0.81 8.2 2.9 1.7 7.2 2.1 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF805 PF05656.14 OEU22344.1 - 0.83 10.1 2.6 2.7 8.5 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) ZapB PF06005.12 OEU22344.1 - 1.4 9.4 15.1 0.15 12.5 8.9 2.7 3 0 0 3 3 3 0 Cell division protein ZapB DUF2511 PF10709.9 OEU22345.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) PDZ_6 PF17820.1 OEU22346.1 - 1.2e-05 25.1 0.0 3.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU22346.1 - 0.00048 20.4 0.1 0.00097 19.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Biotin_lipoyl PF00364.22 OEU22347.1 - 7e-17 61.0 0.2 1.5e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme SAP130_C PF16014.5 OEU22347.1 - 0.0058 15.8 7.7 0.0077 15.4 7.7 1.1 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP130 C-terminus Biotin_lipoyl_2 PF13533.6 OEU22347.1 - 0.039 13.8 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like QRPTase_N PF02749.16 OEU22347.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DEC-1_N PF04625.13 OEU22347.1 - 2.6 7.0 8.9 3.6 6.5 8.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PCRF PF03462.18 OEU22348.1 - 2.4e-38 131.9 0.2 2.4e-38 131.9 0.2 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OEU22348.1 - 6.6e-34 116.3 0.4 6.6e-34 116.3 0.4 1.9 2 0 0 2 2 2 1 RF-1 domain DUF2040 PF09745.9 OEU22348.1 - 0.089 12.9 1.0 0.27 11.3 1.0 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) DnaJ PF00226.31 OEU22349.1 - 1.7e-14 53.6 2.0 1.6e-12 47.4 0.1 3.6 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 OEU22349.1 - 2.4e-12 46.8 0.1 5.7e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU22349.1 - 1.3e-11 44.5 0.3 0.0003 21.0 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OEU22349.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ADH_zinc_N PF00107.26 OEU22350.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OEU22350.1 - 1.5e-05 24.6 0.0 4.1e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus UCH PF00443.29 OEU22351.1 - 5.1e-68 229.3 0.0 6.1e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU22351.1 - 3.6e-17 62.9 0.0 8.4e-17 61.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 OEU22351.1 - 0.0003 20.8 6.0 0.0003 20.8 6.0 3.7 4 0 0 4 4 4 1 MYND finger PHD_Oberon PF07227.11 OEU22351.1 - 0.025 14.5 2.8 0.074 12.9 2.8 1.7 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein SNF2_N PF00176.23 OEU22352.1 - 2.5e-59 200.8 0.0 3.7e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU22352.1 - 4e-17 62.6 0.0 4.7e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22352.1 - 2.5e-08 34.1 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OEU22352.1 - 4.4e-05 22.8 0.0 0.00014 21.2 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OEU22352.1 - 0.00056 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OEU22352.1 - 0.00092 18.5 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 OEU22353.1 - 5.1e-48 163.1 0.0 9.8e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU22353.1 - 3.3e-29 101.5 0.1 5.9e-28 97.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OEU22353.1 - 0.081 12.2 5.6 1.5 8.1 0.0 2.7 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L11_N PF03946.14 OEU22355.1 - 1.4e-20 72.9 0.5 2.3e-20 72.2 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OEU22355.1 - 3.3e-16 59.6 0.1 5.1e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SASA PF03629.18 OEU22356.1 - 4.1e-17 62.6 0.0 1e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Chorein_N PF12624.7 OEU22357.1 - 2e-08 34.4 0.4 8.7e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 PH PF00169.29 OEU22357.1 - 3.2e-07 30.8 0.0 1.3e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 PH domain Vps36-NZF-N PF16988.5 OEU22357.1 - 0.013 14.9 1.8 0.043 13.2 1.8 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Synaptobrevin PF00957.21 OEU22359.1 - 5.6e-15 54.9 0.6 8.6e-15 54.3 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OEU22359.1 - 1.3e-13 50.7 0.0 2.7e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 OEU22359.1 - 0.034 13.8 0.2 0.22 11.2 0.1 2.0 2 1 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region TFR_dimer PF04253.15 OEU22359.1 - 0.15 12.2 0.1 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Taeniidae_ag PF05596.11 OEU22359.1 - 0.15 12.1 0.1 0.45 10.5 0.1 1.8 1 1 1 2 2 2 0 Taeniidae antigen SRP54 PF00448.22 OEU22360.1 - 4.6e-55 186.3 0.2 7.9e-55 185.5 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OEU22360.1 - 2.8e-12 46.7 0.1 7.9e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 OEU22360.1 - 6.8e-06 26.6 0.2 6.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 OEU22360.1 - 5.1e-05 23.1 0.1 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OEU22360.1 - 0.00047 19.2 0.0 0.0016 17.5 0.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OEU22360.1 - 0.00058 20.1 0.4 0.037 14.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OEU22360.1 - 0.00063 19.8 5.0 0.086 12.9 0.1 3.1 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 OEU22360.1 - 0.00067 20.1 0.1 0.0022 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OEU22360.1 - 0.0016 18.4 0.7 0.44 10.5 0.0 2.6 3 0 0 3 3 3 1 NTPase Zeta_toxin PF06414.12 OEU22360.1 - 0.0036 16.6 0.0 0.0096 15.2 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin 6PF2K PF01591.18 OEU22360.1 - 0.0086 15.4 0.2 0.034 13.4 0.0 1.9 1 1 1 2 2 2 1 6-phosphofructo-2-kinase NACHT PF05729.12 OEU22360.1 - 0.0092 15.9 0.2 0.18 11.7 0.0 2.6 2 1 1 3 3 3 1 NACHT domain MMR_HSR1 PF01926.23 OEU22360.1 - 0.012 15.7 2.4 0.36 10.9 2.4 2.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OEU22360.1 - 0.021 14.7 1.7 0.75 9.7 0.1 2.9 2 2 1 3 3 3 0 RsgA GTPase AAA_14 PF13173.6 OEU22360.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OEU22360.1 - 0.059 13.1 0.0 0.23 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 OEU22360.1 - 0.061 13.5 0.0 0.19 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain B12-binding PF02310.19 OEU22360.1 - 0.063 13.3 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain Thymidylate_kin PF02223.17 OEU22360.1 - 0.085 12.5 0.1 0.77 9.4 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase CODH_A_N PF18537.1 OEU22360.1 - 0.13 12.3 0.2 0.49 10.4 0.1 2.1 2 0 0 2 2 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain ETF PF01012.21 OEU22360.1 - 0.4 10.5 2.7 3.7 7.4 0.1 2.6 2 0 0 2 2 2 0 Electron transfer flavoprotein domain ATP_bind_1 PF03029.17 OEU22360.1 - 0.47 10.2 3.6 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ArsA_ATPase PF02374.15 OEU22360.1 - 0.48 9.6 4.1 3.1 6.9 0.1 2.6 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_23 PF13476.6 OEU22360.1 - 5 7.6 7.5 27 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.22 OEU22361.1 - 0.0043 17.3 11.7 0.075 13.3 11.7 2.6 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MCM2_N PF12619.8 OEU22361.1 - 0.099 12.9 0.4 0.27 11.5 0.4 1.7 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 CCDC-167 PF15188.6 OEU22361.1 - 4.5 7.7 11.5 5.1 7.5 1.8 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Fer2 PF00111.27 OEU22363.1 - 1.5e-06 28.1 0.1 2.3e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GTP_cyclohydroI PF01227.22 OEU22367.1 - 5.3e-75 250.8 0.4 5.9e-75 250.6 0.4 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OEU22367.1 - 0.0003 20.9 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Ly-6_related PF06579.12 OEU22367.1 - 0.069 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein 2OG-FeII_Oxy_5 PF13759.6 OEU22368.1 - 0.0013 19.2 0.0 0.0052 17.2 0.0 2.0 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase PDEase_I_N PF08499.12 OEU22368.1 - 0.035 14.0 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal CENP-B_dimeris PF09026.10 OEU22369.1 - 0.0092 16.4 7.1 0.028 14.8 7.1 1.8 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PMM PF03332.13 OEU22370.1 - 1.5e-99 332.3 1.2 1.7e-99 332.1 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OEU22370.1 - 6.5e-06 26.1 0.2 3e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mob_Pre PF01076.19 OEU22371.1 - 0.088 12.6 1.1 1.4 8.7 0.1 2.3 1 1 1 2 2 2 0 Plasmid recombination enzyme Glyco_hydro_99 PF16317.5 OEU22373.1 - 3.2e-30 105.4 2.8 8.3e-30 104.1 2.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 OEU22373.1 - 4.2e-08 33.0 0.0 1.1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase WbsX PTCB-BRCT PF12738.7 OEU22374.1 - 0.0011 18.9 0.0 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain PDZ PF00595.24 OEU22375.1 - 3.2e-05 24.2 0.1 0.00014 22.1 0.1 2.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU22375.1 - 6.9e-05 22.6 0.1 0.00024 20.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain DUF4834 PF16118.5 OEU22375.1 - 0.0093 16.9 0.4 0.0093 16.9 0.4 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4834) PDZ_2 PF13180.6 OEU22375.1 - 0.049 13.9 2.1 0.077 13.3 0.2 2.4 2 0 0 2 2 2 0 PDZ domain DUF2407_C PF13373.6 OEU22375.1 - 0.05 13.8 1.2 0.16 12.1 0.1 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF2304 PF10066.9 OEU22375.1 - 0.83 9.9 2.8 1.5 9.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) YMF19 PF02326.15 OEU22375.1 - 2.3 9.0 7.0 0.32 11.8 0.2 3.1 3 0 0 3 3 3 0 Plant ATP synthase F0 Methyltransf_21 PF05050.12 OEU22376.1 - 2.1e-12 47.4 0.0 3.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 OEU22376.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein EGF PF00008.27 OEU22377.1 - 0.0011 19.2 21.7 0.067 13.5 4.5 2.7 2 1 0 2 2 2 2 EGF-like domain DUF4094 PF13334.6 OEU22377.1 - 0.029 14.8 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) hEGF PF12661.7 OEU22377.1 - 0.15 12.8 15.2 0.36 11.5 3.6 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF PAN_2 PF08276.11 OEU22378.1 - 0.034 14.2 0.8 0.034 14.2 0.8 3.1 3 0 0 3 3 3 0 PAN-like domain DUF3950 PF13132.6 OEU22379.1 - 0.00029 20.5 0.0 0.00029 20.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3950) Ndc1_Nup PF09531.10 OEU22380.1 - 2.5 6.7 5.1 3.9 6.0 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 OEU22380.1 - 6.4 6.6 14.2 3.3 7.5 8.6 2.1 2 0 0 2 2 2 0 SPX domain Chloroa_b-bind PF00504.21 OEU22381.1 - 3e-08 34.4 2.1 0.00046 20.7 0.2 1.5 1 1 1 2 2 2 2 Chlorophyll A-B binding protein UQ_con PF00179.26 OEU22382.1 - 1.1e-41 141.8 0.0 1.2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 OEU22382.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.25 OEU22383.1 - 2.3e-28 99.3 0.0 7.7e-28 97.6 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22383.1 - 1.3e-22 80.3 0.0 2.6e-22 79.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Activator_LAG-3 PF11498.8 OEU22383.1 - 0.0091 15.0 21.6 0.012 14.7 21.6 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 CSRNP_N PF16019.5 OEU22383.1 - 0.032 14.2 3.7 0.045 13.7 3.7 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TFIIA PF03153.13 OEU22383.1 - 0.22 11.5 11.7 0.28 11.2 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 OEU22383.1 - 1.2 7.9 10.2 1.7 7.4 10.2 1.1 1 0 0 1 1 1 0 Androgen receptor K_channel_TID PF07941.11 OEU22384.1 - 4.2 7.9 5.1 8.4 6.9 5.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FA_hydroxylase PF04116.13 OEU22386.1 - 6.8e-21 75.0 23.5 6.8e-21 75.0 23.5 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short_C2 PF13561.6 OEU22387.1 - 1.2e-43 149.3 0.3 1.6e-39 135.9 0.2 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU22387.1 - 0.00012 21.6 0.1 0.003 17.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase LRAT PF04970.13 OEU22387.1 - 0.11 12.8 0.8 0.3 11.4 0.2 2.1 2 1 1 3 3 3 0 Lecithin retinol acyltransferase Prominin PF05478.11 OEU22388.1 - 1.2 7.0 8.1 2.1 6.2 8.1 1.3 1 0 0 1 1 1 0 Prominin Serinc PF03348.15 OEU22389.1 - 0.0021 17.1 0.3 0.0024 16.9 0.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) RXT2_N PF08595.11 OEU22389.1 - 0.0057 16.7 1.1 0.0076 16.3 1.1 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal Med3 PF11593.8 OEU22389.1 - 0.0076 15.5 5.2 0.0091 15.2 5.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal RNA_pol_3_Rpc31 PF11705.8 OEU22389.1 - 0.0095 16.2 4.3 0.013 15.7 4.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 OEU22389.1 - 0.011 16.1 2.5 0.017 15.5 2.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ATG22 PF11700.8 OEU22389.1 - 0.018 13.7 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like CSRNP_N PF16019.5 OEU22389.1 - 0.055 13.4 1.3 0.079 12.9 1.3 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus ATP-synt_E PF05680.12 OEU22389.1 - 0.059 13.7 0.6 0.11 12.9 0.6 1.4 1 0 0 1 1 1 0 ATP synthase E chain FAM176 PF14851.6 OEU22389.1 - 0.06 13.0 0.9 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 FAM176 family CSG2 PF16965.5 OEU22389.1 - 0.11 11.5 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 OEU22389.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 OEU22389.1 - 0.16 11.5 9.6 0.23 11.1 9.6 1.2 1 0 0 1 1 1 0 Spt20 family NOA36 PF06524.12 OEU22389.1 - 2.1 7.6 7.4 2.9 7.1 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein PDZ PF00595.24 OEU22391.1 - 0.0029 17.9 0.1 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain SLAC1 PF03595.17 OEU22391.1 - 0.014 14.7 0.2 0.02 14.1 0.2 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel BPS1 PF05633.11 OEU22391.1 - 7.1 5.5 7.5 11 4.9 7.5 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related NAD_binding_8 PF13450.6 OEU22392.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_1 PF00561.20 OEU22394.1 - 2.1e-25 89.8 0.1 8.8e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU22394.1 - 1.2e-19 71.8 0.0 1.6e-19 71.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OEU22394.1 - 4e-10 39.8 0.2 4e-08 33.3 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 OEU22394.1 - 2.3e-09 36.9 0.0 3.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OEU22394.1 - 1.6e-06 28.4 0.0 2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 OEU22394.1 - 1.9e-05 23.5 0.0 3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 OEU22394.1 - 8.5e-05 21.7 0.0 0.00021 20.4 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase DUF915 PF06028.11 OEU22394.1 - 0.00018 20.9 0.3 0.13 11.5 0.1 2.5 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 OEU22394.1 - 0.00029 19.8 0.0 0.00051 19.0 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF676 PF05057.14 OEU22394.1 - 0.00051 19.6 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OEU22394.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OEU22394.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 OEU22394.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 OEU22394.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 OEU22394.1 - 0.033 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 OEU22394.1 - 0.034 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydro_lipase PF04083.16 OEU22394.1 - 0.053 13.1 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region LCAT PF02450.15 OEU22394.1 - 0.065 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2920 PF11144.8 OEU22394.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Palm_thioest PF02089.15 OEU22394.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase RAG2_PHD PF13341.6 OEU22394.1 - 0.15 12.2 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 RAG2 PHD domain E1-E2_ATPase PF00122.20 OEU22395.1 - 2.1e-47 161.0 10.3 2.9e-46 157.3 3.4 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OEU22395.1 - 1.9e-28 99.4 6.2 1.9e-28 99.4 6.2 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 OEU22395.1 - 1.2e-18 66.5 0.2 2.6e-18 65.4 0.2 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OEU22395.1 - 2.8e-18 67.0 1.1 2e-13 51.1 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU22395.1 - 5.2e-15 55.3 0.0 1.9e-14 53.5 0.0 2.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OEU22395.1 - 0.0011 18.7 2.0 0.0019 18.0 2.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hol_Tox PF16935.5 OEU22395.1 - 0.03 14.4 0.2 0.13 12.3 0.2 2.2 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) DUF2207 PF09972.9 OEU22395.1 - 0.058 12.2 0.0 0.058 12.2 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OEU22395.1 - 0.086 13.2 3.2 8.4 6.8 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF5383 PF17355.2 OEU22395.1 - 0.25 11.7 1.2 3 8.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) DUF4064 PF13273.6 OEU22395.1 - 4.1 7.7 24.4 0.018 15.3 3.7 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Prok-E2_B PF14461.6 OEU22396.1 - 0.046 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.25 OEU22397.1 - 1.6e-22 80.2 0.0 2.1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22397.1 - 2e-17 63.3 0.0 2.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 OEU22397.1 - 0.00093 18.9 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 APH PF01636.23 OEU22397.1 - 0.0099 15.8 0.1 0.045 13.7 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family SCAB-ABD PF16711.5 OEU22397.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein DEAD PF00270.29 OEU22398.1 - 9.4e-37 126.5 0.0 2.2e-36 125.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU22398.1 - 1.3e-18 67.4 0.0 3e-17 63.0 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OEU22398.1 - 1.1e-10 41.6 0.3 2.6e-10 40.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OEU22398.1 - 3.3e-09 37.0 0.0 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU22398.1 - 0.032 14.5 0.1 14 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sulfotransfer_3 PF13469.6 OEU22399.1 - 8.1e-05 23.1 0.1 0.33 11.3 0.0 2.9 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 OEU22399.1 - 0.0024 17.4 1.3 0.0039 16.7 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase domain zf-CXXC PF02008.20 OEU22400.1 - 6.3e-05 22.9 12.7 0.00042 20.3 12.7 2.6 1 0 0 1 1 1 1 CXXC zinc finger domain Pyr_redox_2 PF07992.14 OEU22401.1 - 0.0021 17.3 0.2 0.0078 15.5 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU22401.1 - 0.0047 16.5 0.2 0.008 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU22401.1 - 0.0081 16.4 1.6 0.016 15.4 1.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OEU22401.1 - 0.011 15.0 1.2 0.019 14.3 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OEU22401.1 - 0.047 12.4 0.7 0.072 11.8 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OEU22401.1 - 0.066 12.3 0.9 0.1 11.7 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain CSRNP_N PF16019.5 OEU22402.1 - 3.3e-10 40.2 0.0 3.3e-10 40.2 0.0 4.8 2 2 3 5 5 5 1 Cysteine/serine-rich nuclear protein N-terminus Dicty_REP PF05086.12 OEU22402.1 - 0.014 13.4 14.5 0.022 12.8 14.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3915 PF13054.6 OEU22402.1 - 0.026 14.5 2.2 1 9.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Serinc PF03348.15 OEU22402.1 - 3.1 6.6 4.4 7.2 5.4 4.4 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) TCR PF03638.15 OEU22402.1 - 5.9 7.3 16.4 2.4 8.5 10.4 2.4 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain DUF3854 PF12965.7 OEU22403.1 - 0.022 14.7 0.5 0.037 14.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) Tfb5 PF06331.12 OEU22403.1 - 0.15 12.1 1.1 0.49 10.4 1.1 1.9 1 1 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 LtrA PF06772.11 OEU22406.1 - 1.1e-13 51.1 31.7 1.8e-13 50.4 31.7 1.4 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4886 PF16227.5 OEU22406.1 - 0.046 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) SNRNP27 PF08648.12 OEU22407.1 - 7e-25 86.9 3.6 7e-25 86.9 3.6 2.5 4 0 0 4 4 4 1 U4/U6.U5 small nuclear ribonucleoproteins DUF2001 PF09393.10 OEU22407.1 - 0.052 13.5 0.3 0.12 12.4 0.1 1.6 2 0 0 2 2 2 0 Phage tail tube protein Dynamitin PF04912.14 OEU22408.1 - 1.4e-38 133.2 26.9 2.5e-38 132.4 26.9 1.3 1 1 0 1 1 1 1 Dynamitin Hemerythrin PF01814.23 OEU22408.1 - 0.049 14.3 5.3 0.42 11.2 0.1 2.8 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain DUF724 PF05266.14 OEU22408.1 - 0.085 12.7 0.3 0.085 12.7 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF1722 PF08349.11 OEU22408.1 - 0.11 12.8 2.2 0.14 12.5 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) OmpH PF03938.14 OEU22408.1 - 0.16 12.3 14.2 0.5 10.7 3.1 3.1 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) HSBP1 PF06825.12 OEU22408.1 - 0.31 10.9 10.4 0.33 10.8 0.3 4.5 5 1 0 5 5 5 0 Heat shock factor binding protein 1 Lzipper-MIP1 PF14389.6 OEU22408.1 - 0.32 11.3 13.3 3.5 8.0 1.3 4.4 2 1 3 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 Corona_nucleoca PF00937.18 OEU22408.1 - 0.38 9.8 6.0 0.24 10.4 4.1 1.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein CorA PF01544.18 OEU22408.1 - 1.2 8.4 12.7 0.017 14.4 1.5 2.5 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein PspB PF06667.12 OEU22408.1 - 3.3 7.8 11.1 12 6.1 0.1 4.5 5 0 0 5 5 5 0 Phage shock protein B DUF4332 PF14229.6 OEU22409.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) RCC1 PF00415.18 OEU22410.1 - 3.8e-22 78.7 6.4 2e-06 28.3 0.1 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU22410.1 - 4.1e-18 64.7 7.2 0.0014 18.4 0.2 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 OEU22410.1 - 0.024 14.9 0.2 7.8 6.8 0.0 3.0 3 1 0 3 3 3 0 Putative heavy-metal chelation DHHW PF14286.6 OEU22411.1 - 0.044 13.1 0.9 0.053 12.8 0.7 1.3 1 1 0 1 1 1 0 DHHW protein zf-MYND PF01753.18 OEU22412.1 - 1.3e-13 50.8 40.1 7.1e-10 38.8 16.5 2.8 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 OEU22412.1 - 0.064 13.4 22.9 0.079 13.1 8.7 3.1 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Gal-3-0_sulfotr PF06990.11 OEU22413.1 - 1.5e-06 27.4 1.4 0.03 13.2 0.0 2.3 2 1 0 2 2 2 2 Galactose-3-O-sulfotransferase NES_C_h PF18208.1 OEU22413.1 - 0.0067 16.7 1.0 0.28 11.5 0.1 2.5 2 0 0 2 2 2 2 Nicking enzyme C-terminal middle helical domain Isochorismatase PF00857.20 OEU22414.1 - 1e-41 143.0 0.0 1.1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.28 OEU22415.1 - 5.6e-87 292.1 0.0 6.6e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HTH_3 PF01381.22 OEU22416.1 - 1.6e-13 50.5 0.5 3e-13 49.6 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OEU22416.1 - 0.003 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MBF1 PF08523.10 OEU22416.1 - 0.0036 17.7 0.4 0.0036 17.7 0.4 3.0 3 2 0 3 3 3 1 Multiprotein bridging factor 1 HTH_19 PF12844.7 OEU22416.1 - 0.0059 16.6 0.1 0.0099 15.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain AAA PF00004.29 OEU22417.1 - 4.9e-90 298.8 0.0 8.3e-48 162.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU22417.1 - 2e-20 72.3 0.5 6.9e-11 41.8 0.0 2.8 2 1 0 2 2 2 2 AAA+ lid domain AAA_33 PF13671.6 OEU22417.1 - 4.1e-13 49.7 0.0 7.5e-07 29.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OEU22417.1 - 1.1e-12 48.6 0.1 0.00023 21.6 0.1 4.5 3 2 0 3 3 2 2 AAA ATPase domain RuvB_N PF05496.12 OEU22417.1 - 5.3e-12 45.8 0.0 3.5e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OEU22417.1 - 1.1e-10 41.6 0.0 0.00013 22.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OEU22417.1 - 3.2e-10 40.4 0.2 0.023 15.0 0.0 4.4 3 2 1 4 4 4 3 AAA domain AAA_2 PF07724.14 OEU22417.1 - 3.9e-09 36.8 0.0 0.00065 19.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OEU22417.1 - 2.9e-08 33.8 0.0 0.0078 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU22417.1 - 3.7e-08 33.7 0.0 0.013 15.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OEU22417.1 - 8.9e-08 32.1 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 OEU22417.1 - 9.7e-08 32.1 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OEU22417.1 - 7.3e-07 29.8 0.0 0.039 14.5 0.0 2.9 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.13 OEU22417.1 - 7.9e-07 28.6 0.0 0.012 14.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 OEU22417.1 - 9.5e-07 28.9 0.0 0.033 14.1 0.0 2.8 3 0 0 3 3 2 2 NACHT domain Mg_chelatase PF01078.21 OEU22417.1 - 1.9e-06 27.4 0.5 0.028 13.8 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OEU22417.1 - 2.3e-06 28.2 0.0 0.041 14.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 OEU22417.1 - 4.5e-06 27.1 0.0 0.096 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OEU22417.1 - 4.5e-06 27.0 0.0 0.061 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 OEU22417.1 - 2.2e-05 23.8 0.1 0.24 10.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 OEU22417.1 - 7.3e-05 22.8 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_3 PF07726.11 OEU22417.1 - 8.5e-05 22.4 0.0 0.26 11.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OEU22417.1 - 0.00017 21.6 0.0 0.13 12.1 0.0 3.0 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OEU22417.1 - 0.0003 20.6 0.0 0.27 10.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OEU22417.1 - 0.00034 19.9 0.0 0.13 11.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.26 OEU22417.1 - 0.00038 20.2 0.0 0.22 11.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OEU22417.1 - 0.00042 20.1 0.0 0.81 9.4 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 OEU22417.1 - 0.00043 19.4 0.0 0.16 11.1 0.1 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 OEU22417.1 - 0.00057 19.4 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_11 PF13086.6 OEU22417.1 - 0.0008 19.3 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OEU22417.1 - 0.0011 18.6 0.0 0.74 9.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Cytidylate_kin2 PF13189.6 OEU22417.1 - 0.0013 19.0 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family PduV-EutP PF10662.9 OEU22417.1 - 0.0022 17.7 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.18 OEU22417.1 - 0.0029 17.5 0.0 3.4 7.5 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein ATPase PF06745.13 OEU22417.1 - 0.0038 16.6 0.0 0.48 9.7 0.0 2.6 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 OEU22417.1 - 0.0048 16.4 0.1 1.6 8.1 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.15 OEU22417.1 - 0.0064 16.4 0.0 7.2 6.5 0.0 3.1 3 0 0 3 3 3 0 NTPase Vps4_C PF09336.10 OEU22417.1 - 0.0099 15.9 0.0 0.79 9.8 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain CPT PF07931.12 OEU22417.1 - 0.01 15.7 0.0 1.7 8.5 0.0 3.0 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 OEU22417.1 - 0.013 15.7 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 OEU22417.1 - 0.023 15.0 0.6 4.5 7.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 OEU22417.1 - 0.023 14.8 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 OEU22417.1 - 0.029 14.1 0.1 8.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase ATP-synt_ab PF00006.25 OEU22417.1 - 0.044 13.4 0.0 8 6.1 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 OEU22417.1 - 0.084 12.6 0.1 13 5.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 OEU22417.1 - 0.099 11.9 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ADK PF00406.22 OEU22417.1 - 0.12 12.5 0.3 14 5.8 0.0 2.7 3 0 0 3 3 2 0 Adenylate kinase DUF815 PF05673.13 OEU22417.1 - 0.14 11.3 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OEU22417.1 - 0.14 11.4 0.0 42 3.2 0.0 3.2 2 2 0 4 4 4 0 KAP family P-loop domain FeoB_N PF02421.18 OEU22417.1 - 0.15 11.6 0.3 9.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Hydin_ADK PF17213.3 OEU22417.1 - 0.15 12.3 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AFG1_ATPase PF03969.16 OEU22417.1 - 0.2 10.5 0.1 1.4 7.7 0.0 2.2 3 0 0 3 3 2 0 AFG1-like ATPase Proteasome PF00227.26 OEU22418.1 - 2.3e-10 40.3 0.0 4.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OEU22418.1 - 6.1e-09 35.4 0.3 1.3e-08 34.4 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NIF PF03031.18 OEU22419.1 - 1.8e-39 135.0 0.0 3.9e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Erf4 PF10256.9 OEU22420.1 - 0.0087 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Tube PF17212.3 OEU22421.1 - 0.055 13.5 0.6 0.09 12.8 0.6 1.3 1 0 0 1 1 1 0 Tail tubular protein Transket_pyr PF02779.24 OEU22422.1 - 1.1e-65 220.7 0.0 1.8e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OEU22422.1 - 1e-57 195.4 0.0 1.6e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OEU22422.1 - 5.4e-50 169.0 0.0 8.4e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OEU22422.1 - 2e-15 56.1 1.6 5e-15 54.8 1.6 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 OEU22422.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 TPR_12 PF13424.6 OEU22425.1 - 3.3e-17 62.6 5.7 4.4e-09 36.5 0.1 5.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU22425.1 - 8.9e-12 44.5 18.5 1.5e-07 31.1 0.1 6.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OEU22425.1 - 0.006 16.4 1.0 0.12 12.2 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OEU22425.1 - 0.0092 16.6 3.3 0.058 14.0 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OEU22425.1 - 0.13 12.4 0.0 0.13 12.4 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OEU22425.1 - 0.15 12.3 2.0 8.4 6.9 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Maf1 PF09174.10 OEU22425.1 - 1.1 9.4 10.3 0.39 10.9 2.4 2.7 2 1 0 2 2 2 0 Maf1 regulator SET PF00856.28 OEU22426.1 - 1.9e-10 41.4 0.1 8.3e-08 32.8 0.0 3.9 4 1 0 4 4 4 1 SET domain EF-hand_1 PF00036.32 OEU22427.1 - 4.5e-12 44.6 1.2 1.7e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU22427.1 - 1.1e-09 37.4 0.3 0.00021 20.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU22427.1 - 2.4e-09 36.3 3.7 0.00029 20.2 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU22427.1 - 6.1e-08 33.0 0.6 9.6e-08 32.4 0.6 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 OEU22427.1 - 6.7e-06 26.0 0.6 0.039 13.9 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 OEU22427.1 - 0.00015 21.5 1.8 0.01 15.7 0.6 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 OEU22427.1 - 0.0052 16.6 0.6 1.9 8.4 0.1 2.2 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 OEU22427.1 - 0.032 14.5 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Dicty_REP PF05086.12 OEU22427.1 - 0.38 8.7 1.9 0.38 8.7 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hydrolase_like PF13242.6 OEU22428.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like Exo_endo_phos PF03372.23 OEU22430.1 - 0.00026 20.6 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 OEU22430.1 - 0.002 17.7 0.0 0.0073 15.8 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU22430.1 - 0.0037 17.9 3.8 0.0037 17.9 3.8 2.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase GARS_A PF01071.19 OEU22430.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Abhydrolase_2 PF02230.16 OEU22432.1 - 3.3e-47 161.1 0.0 3.6e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OEU22432.1 - 5e-06 25.9 0.8 0.21 10.8 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 OEU22432.1 - 6.3e-05 22.7 0.0 0.00013 21.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OEU22432.1 - 0.0007 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OEU22432.1 - 0.0013 18.5 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OEU22432.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Apyrase PF06079.11 OEU22433.1 - 1.4e-106 356.0 1.4 1.7e-106 355.7 1.4 1.1 1 0 0 1 1 1 1 Apyrase ERG4_ERG24 PF01222.17 OEU22434.1 - 3.1e-58 197.6 16.2 3.7e-58 197.3 16.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OEU22434.1 - 1.5e-07 31.1 0.2 3e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_L29e PF01779.17 OEU22435.1 - 7.7e-18 64.5 8.8 7.7e-18 64.5 8.8 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family Abhydrolase_6 PF12697.7 OEU22436.1 - 2.7e-08 34.7 0.0 3.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.22 OEU22436.1 - 8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.13 OEU22436.1 - 0.00038 20.4 0.0 0.0011 18.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OEU22436.1 - 0.0021 18.0 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OEU22436.1 - 0.0034 16.7 0.0 0.028 13.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU22436.1 - 0.0063 16.0 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 OEU22436.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain PITH PF06201.13 OEU22437.1 - 8.7e-34 116.9 0.0 1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain PDZ PF00595.24 OEU22438.1 - 0.0001 22.6 0.2 0.00016 21.9 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU22438.1 - 0.00027 21.2 2.7 0.00067 19.9 2.7 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU22438.1 - 0.00027 20.7 0.2 0.00048 19.9 0.2 1.4 1 0 0 1 1 1 1 PDZ domain Orthoreo_P10 PF07204.11 OEU22438.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 PDZ PF00595.24 OEU22439.1 - 0.00017 21.9 1.5 0.00025 21.3 0.6 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OEU22439.1 - 0.056 13.3 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 OEU22439.1 - 0.52 10.7 4.5 0.25 11.7 1.5 2.1 2 0 0 2 2 2 0 PDZ domain ThiF PF00899.21 OEU22441.1 - 2.3e-88 295.7 0.2 7.8e-70 235.0 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OEU22441.1 - 2.5e-81 273.3 0.2 2.5e-81 273.3 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 OEU22441.1 - 5e-28 97.6 0.3 1.5e-27 96.1 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OEU22441.1 - 1.2e-15 57.5 0.0 2.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 OEU22441.1 - 1.7e-14 53.7 0.1 3.8e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain YhdX PF17444.2 OEU22441.1 - 0.41 10.5 2.0 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized YhdX-like Utp12 PF04003.12 OEU22442.1 - 1.7e-06 28.3 1.1 5.7e-06 26.6 1.1 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family COX_ARM PF06481.14 OEU22442.1 - 0.012 15.5 0.5 2 8.4 0.1 2.5 2 0 0 2 2 2 0 COX Aromatic Rich Motif DUF4892 PF16234.5 OEU22442.1 - 0.022 14.2 0.0 12 5.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4892) Hpt PF01627.23 OEU22442.1 - 0.027 14.7 0.5 0.066 13.5 0.5 1.7 1 0 0 1 1 1 0 Hpt domain DUF5018 PF16410.5 OEU22442.1 - 0.046 12.4 0.5 0.13 10.9 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5018) PQQ_2 PF13360.6 OEU22442.1 - 0.075 12.6 0.3 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain Met_10 PF02475.16 OEU22443.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Bro-N PF02498.17 OEU22443.1 - 0.096 13.4 0.1 0.32 11.7 0.0 1.9 2 0 0 2 2 2 0 BRO family, N-terminal domain Ribosomal_L18A PF01775.17 OEU22445.1 - 2.8e-51 172.7 1.4 3.6e-51 172.3 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Rad60-SLD PF11976.8 OEU22446.1 - 1.2e-17 63.4 0.6 1.4e-17 63.3 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OEU22446.1 - 4.6e-11 42.3 0.3 5.2e-11 42.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family 2OG-FeII_Oxy_3 PF13640.6 OEU22447.1 - 1.7e-05 25.6 0.2 5.4e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cation_efflux PF01545.21 OEU22448.1 - 4e-16 59.3 0.0 1.1e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 Cation efflux family Got1 PF04178.12 OEU22448.1 - 2.1 8.8 7.1 0.64 10.5 0.2 2.7 2 1 0 2 2 2 0 Got1/Sft2-like family HMG_box PF00505.19 OEU22450.1 - 1.7e-17 63.6 0.1 2.1e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU22450.1 - 5.7e-15 55.7 0.1 7.9e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OEU22450.1 - 0.00055 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain MlaC PF05494.12 OEU22450.1 - 0.074 12.8 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 MlaC protein HMG_box PF00505.19 OEU22451.1 - 1.4e-39 134.4 9.3 2.1e-20 72.9 3.1 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OEU22451.1 - 1.2e-23 83.4 10.0 1.2e-12 48.2 3.5 2.1 2 0 0 2 2 2 2 HMG-box domain Ccdc124 PF06244.12 OEU22451.1 - 1.3e-05 25.8 0.3 0.0037 17.8 0.1 2.3 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 OEU22451.1 - 4.4e-05 23.4 0.4 0.27 11.2 0.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Glyco_H_20C_C PF18088.1 OEU22451.1 - 0.0021 18.0 0.8 0.28 11.0 0.1 2.1 2 0 0 2 2 2 2 Glycoside Hydrolase 20C C-terminal domain CHDNT PF08073.12 OEU22451.1 - 0.0039 17.1 0.1 0.51 10.3 0.1 2.2 2 0 0 2 2 2 1 CHDNT (NUC034) domain YqzL PF14006.6 OEU22451.1 - 0.089 13.2 0.2 26 5.3 0.0 2.6 2 0 0 2 2 2 0 YqzL-like protein HSF_DNA-bind PF00447.17 OEU22452.1 - 2.4e-17 63.3 0.2 2.4e-17 63.3 0.2 2.1 2 1 0 2 2 2 1 HSF-type DNA-binding FixH PF05751.11 OEU22452.1 - 0.27 11.2 1.6 0.53 10.3 1.6 1.4 1 0 0 1 1 1 0 FixH PYST-C1 PF09690.10 OEU22452.1 - 0.48 10.2 11.5 0.079 12.7 2.1 2.6 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Omega-toxin PF06357.11 OEU22453.1 - 6.9 6.6 6.0 0.76 9.6 0.1 2.6 2 0 0 2 2 2 0 Omega-atracotoxin DUF1990 PF09348.10 OEU22454.1 - 2.4e-16 60.2 0.2 1.4e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1990) PgpA PF04608.13 OEU22455.1 - 0.036 14.1 0.8 0.19 11.7 0.4 2.1 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A CTXphi_pIII-N1 PF16710.5 OEU22455.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Sigma_reg_N PF13800.6 OEU22455.1 - 0.13 12.6 1.3 0.48 10.8 1.3 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal fn3 PF00041.21 OEU22456.1 - 0.00016 22.0 0.1 0.00032 21.0 0.1 1.6 1 1 0 1 1 1 1 Fibronectin type III domain Pro-NT_NN PF07421.11 OEU22457.1 - 0.011 16.0 0.6 0.027 14.7 0.6 1.6 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Peptidase_C13 PF01650.18 OEU22458.1 - 2.6e-33 115.6 0.3 3e-33 115.4 0.3 1.0 1 0 0 1 1 1 1 Peptidase C13 family NAD_binding_1 PF00175.21 OEU22459.1 - 4e-28 98.2 0.0 1e-27 96.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OEU22459.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.20 OEU22459.1 - 0.024 14.2 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Cyclin_N PF00134.23 OEU22460.1 - 2e-39 134.3 4.4 2.5e-39 133.9 0.6 2.1 1 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU22460.1 - 4.6e-09 36.4 0.4 9e-09 35.5 0.4 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cytokin_check_N PF10407.9 OEU22460.1 - 0.031 14.2 0.3 9.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus SNARE_assoc PF09335.11 OEU22462.1 - 5.4e-16 59.2 6.7 5.4e-16 59.2 6.7 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein Phage_holin_8 PF16931.5 OEU22462.1 - 0.016 15.2 0.9 0.016 15.2 0.9 1.8 2 0 0 2 2 2 0 Putative phage holin Phage_holin_Dp1 PF16938.5 OEU22462.1 - 0.15 12.3 4.4 0.2 11.9 1.8 2.3 2 0 0 2 2 2 0 Putative phage holin Dp-1 SdpI PF13630.6 OEU22462.1 - 0.79 9.9 0.0 0.79 9.9 0.0 2.7 3 1 0 3 3 3 0 SdpI/YhfL protein family TssN PF17555.2 OEU22462.1 - 2.5 7.4 6.3 0.16 11.3 1.2 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF202 PF02656.15 OEU22462.1 - 9.8 6.7 8.1 1.4 9.4 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) ArsP_1 PF03773.13 OEU22463.1 - 1.2e-23 83.7 14.9 2.6e-23 82.6 9.5 2.3 1 1 1 2 2 2 2 Predicted permease Calreticulin PF00262.18 OEU22463.1 - 0.025 13.5 0.1 0.043 12.7 0.1 1.3 1 0 0 1 1 1 0 Calreticulin family DnaJ PF00226.31 OEU22464.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OEU22464.1 - 0.0025 17.8 1.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Pam16 T2SSM PF04612.12 OEU22464.1 - 0.018 15.1 2.8 0.018 15.1 2.8 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M COX6A PF02046.15 OEU22464.1 - 0.032 14.7 1.8 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIa AIM3 PF17096.5 OEU22464.1 - 0.42 11.6 9.7 3.1 8.8 0.9 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DASH_Spc19 PF08287.11 OEU22464.1 - 0.88 9.5 15.4 0.16 11.9 4.3 2.3 2 0 0 2 2 2 0 Spc19 PBP1_TM PF14812.6 OEU22464.1 - 2.5 8.5 14.6 0.82 10.1 3.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PhetRS_B1 PF18262.1 OEU22465.1 - 7.4e-37 125.4 0.5 4.8e-35 119.6 0.1 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain tRNA_synthFbeta PF17759.1 OEU22465.1 - 7.2e-36 123.6 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 OEU22465.1 - 1.2e-23 83.6 0.1 2.2e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OEU22465.1 - 4.6e-17 62.1 0.0 5.9e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 OEU22465.1 - 0.067 12.7 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PP2C PF00481.21 OEU22466.1 - 8.3e-26 91.2 0.0 1.1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Telomere_reg-2 PF10193.9 OEU22467.1 - 6e-21 74.9 0.9 1.9e-19 70.1 0.3 2.7 2 0 0 2 2 2 1 Telomere length regulation protein DUF5567 PF17722.1 OEU22470.1 - 0.034 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5567) Phage_holin_2_1 PF04971.12 OEU22471.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S Aldedh PF00171.22 OEU22472.1 - 7.7e-125 417.0 0.0 8.7e-125 416.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DRTGG PF07085.12 OEU22472.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain ABC_tran PF00005.27 OEU22473.1 - 0.00068 20.2 0.2 0.0015 19.0 0.2 1.7 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 OEU22473.1 - 0.0046 16.9 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain SRP54 PF00448.22 OEU22473.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OEU22473.1 - 0.01 15.5 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OEU22473.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OEU22473.1 - 0.022 15.3 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OEU22473.1 - 0.032 14.5 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 OEU22473.1 - 0.054 13.4 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 OEU22473.1 - 0.1 12.8 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.20 OEU22473.1 - 0.11 11.1 1.0 0.2 10.3 1.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Mso1_Sec1_bdg PF14475.6 OEU22474.1 - 0.029 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Sec1-binding region of Mso1 SMC_Nse1 PF07574.13 OEU22474.1 - 0.12 12.2 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Gar1 PF04410.14 OEU22474.1 - 0.17 11.7 3.5 0.19 11.5 1.7 1.8 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region Complex1_LYR_2 PF13233.6 OEU22475.1 - 2.1e-12 47.6 0.8 2.6e-12 47.3 0.8 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OEU22475.1 - 1.2e-08 34.8 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PTCB-BRCT PF12738.7 OEU22476.1 - 3.9e-24 84.4 2.5 7.5e-14 51.4 0.2 3.3 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 OEU22476.1 - 2.1e-22 79.3 0.6 2.7e-09 37.3 0.2 5.3 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OEU22476.1 - 2.4e-18 66.3 1.7 2.3e-07 31.1 0.0 4.6 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 OEU22476.1 - 0.69 10.0 4.0 12 6.0 0.0 4.0 4 1 1 5 5 5 0 BRCA1 C Terminus (BRCT) domain ECH_2 PF16113.5 OEU22477.1 - 1.6e-105 353.3 0.0 1.4e-104 350.2 0.0 2.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OEU22477.1 - 3.4e-22 79.0 1.5 1.9e-10 40.5 0.0 3.5 2 1 2 4 4 4 3 Enoyl-CoA hydratase/isomerase Roughex PF06020.11 OEU22477.1 - 0.022 13.9 0.4 0.036 13.2 0.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4660 PF15559.6 OEU22477.1 - 0.037 14.3 0.3 0.099 13.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Strep_his_triad PF04270.13 OEU22477.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Streptococcal histidine triad protein SseC PF04888.12 OEU22478.1 - 0.012 15.2 2.3 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF4710 PF15828.5 OEU22478.1 - 0.093 12.9 1.6 0.13 12.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) RRM_1 PF00076.22 OEU22479.1 - 1.7e-22 79.0 0.1 5.7e-11 42.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU22479.1 - 4.1e-06 26.8 0.2 0.09 12.9 0.0 3.1 2 2 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 OEU22479.1 - 0.00021 21.1 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain mCpol PF18182.1 OEU22479.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 minimal CRISPR polymerase domain AMP-binding PF00501.28 OEU22480.1 - 5.7e-33 114.1 0.0 5.1e-32 111.0 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OEU22480.1 - 0.00026 21.9 0.0 0.00055 20.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YGGT PF02325.17 OEU22481.1 - 6.1e-18 65.0 3.8 1.1e-17 64.2 3.8 1.4 1 0 0 1 1 1 1 YGGT family ELO PF01151.18 OEU22482.1 - 9.2e-53 179.3 28.6 1.1e-52 179.1 28.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MrpF_PhaF PF04066.13 OEU22482.1 - 0.25 11.7 4.7 5.4 7.5 0.1 2.9 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Abhydrolase_2 PF02230.16 OEU22483.1 - 6.6e-13 49.0 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OEU22483.1 - 0.0005 19.8 0.0 0.0014 18.3 0.0 1.9 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 OEU22483.1 - 0.0036 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 OEU22483.1 - 0.0096 16.1 0.0 0.032 14.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 OEU22483.1 - 0.011 15.1 0.0 0.33 10.2 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OEU22483.1 - 0.015 15.9 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family MINDY_DUB PF04424.13 OEU22484.1 - 2.6e-24 85.5 0.0 7.7e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 MINDY deubiquitinase GTSE1_N PF15259.6 OEU22484.1 - 3.1 8.0 13.5 2.7 8.2 1.5 3.2 3 0 0 3 3 3 0 G-2 and S-phase expressed 1 Glyco_transf_8 PF01501.20 OEU22485.1 - 5.5e-07 29.4 0.4 0.00045 19.8 0.1 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 OEU22485.1 - 0.0031 17.0 0.1 0.0056 16.1 0.1 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 DUF3240 PF11582.8 OEU22485.1 - 0.096 12.8 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) MeaB PF03308.16 OEU22486.1 - 2.3e-62 210.4 0.0 2.9e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PPR_2 PF13041.6 OEU22487.1 - 1.6e-40 137.1 9.6 4.9e-14 52.2 0.0 7.8 7 1 1 8 8 8 5 PPR repeat family PPR_3 PF13812.6 OEU22487.1 - 5.1e-32 109.8 3.4 1.6e-08 34.5 0.0 7.0 6 1 1 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 OEU22487.1 - 7.9e-21 72.8 8.6 1.4e-06 28.1 0.1 8.7 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.7 OEU22487.1 - 2.4e-19 68.7 0.0 0.00042 19.9 0.0 6.6 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 OEU22487.1 - 4.9e-13 48.9 2.7 2.7e-08 33.4 0.0 3.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OEU22487.1 - 1.3e-05 25.6 0.1 20 6.3 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ELYS PF13934.6 OEU22487.1 - 0.0017 18.3 0.0 0.006 16.6 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore complex assembly TPR_19 PF14559.6 OEU22487.1 - 0.005 17.3 0.4 0.89 10.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PDZ_2 PF13180.6 OEU22487.1 - 0.0066 16.7 1.2 0.56 10.6 0.0 3.4 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 OEU22487.1 - 0.019 14.8 0.4 0.47 10.3 0.1 2.6 2 0 0 2 2 2 0 PDZ domain TPR_8 PF13181.6 OEU22487.1 - 0.035 14.3 0.1 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PDZ PF00595.24 OEU22487.1 - 0.049 14.0 0.0 3.9 7.9 0.0 2.7 2 0 0 2 2 2 0 PDZ domain Asp_Arg_Hydrox PF05118.15 OEU22488.1 - 1.3e-38 132.3 0.0 2.2e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Abhydrolase_1 PF00561.20 OEU22489.1 - 2.5e-16 60.1 0.4 1e-15 58.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU22489.1 - 5.1e-14 53.4 0.0 7.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU22489.1 - 2.1e-10 40.3 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OEU22489.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 OEU22489.1 - 0.00061 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 OEU22489.1 - 0.0027 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OEU22489.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Chlorophyllase2 PF12740.7 OEU22489.1 - 0.018 14.0 0.0 0.068 12.1 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF1057 PF06342.12 OEU22489.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 OEU22489.1 - 0.028 14.5 0.0 0.045 13.9 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 OEU22489.1 - 0.03 13.8 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OEU22489.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold S1 PF00575.23 OEU22490.1 - 3.4e-25 88.2 0.0 7.8e-15 55.0 0.0 2.8 2 1 0 2 2 2 2 S1 RNA binding domain CDC45 PF02724.14 OEU22490.1 - 0.027 12.8 2.0 0.039 12.2 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TOBE_2 PF08402.10 OEU22490.1 - 0.093 12.9 0.1 1.7 8.9 0.0 2.5 2 1 0 2 2 2 0 TOBE domain RNase_II_C_S1 PF18614.1 OEU22490.1 - 0.11 12.4 0.1 13 5.8 0.1 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain BNIP2 PF12496.8 OEU22490.1 - 0.15 12.5 8.9 0.19 12.2 4.2 2.2 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 VSG_B PF13206.6 OEU22490.1 - 0.28 10.4 2.1 0.4 9.9 2.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain S1_2 PF13509.6 OEU22490.1 - 0.3 11.2 4.7 6.2 7.0 0.0 3.6 3 1 0 3 3 3 0 S1 domain DUF2431 PF10354.9 OEU22491.1 - 1.2e-18 68.0 0.2 1.2e-18 68.0 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) S4 PF01479.25 OEU22491.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain HALZ PF02183.18 OEU22492.1 - 0.014 15.6 0.3 0.021 15.1 0.3 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper WWE PF02825.20 OEU22493.1 - 1.3e-07 32.1 0.1 4.5e-07 30.4 0.1 2.0 1 0 0 1 1 1 1 WWE domain Beta_helix PF13229.6 OEU22493.1 - 0.032 14.1 0.6 0.032 14.1 0.6 4.2 1 1 3 4 4 4 0 Right handed beta helix region Methyltransf_32 PF13679.6 OEU22494.1 - 2.3e-37 128.4 0.2 5.6e-37 127.2 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU22494.1 - 8.8e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 OEU22494.1 - 0.0059 16.2 6.2 0.81 9.2 0.5 3.6 3 1 0 4 4 4 2 Methyltransferase TRM13 Methyltransf_25 PF13649.6 OEU22494.1 - 0.01 16.5 0.0 0.032 14.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain IGPD PF00475.18 OEU22495.1 - 6.1e-33 114.1 0.2 8.9e-33 113.6 0.2 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF674 PF05056.12 OEU22496.1 - 0.015 14.2 0.3 0.035 13.0 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF674) PBP1_TM PF14812.6 OEU22498.1 - 0.027 14.8 1.3 0.23 11.8 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UCH PF00443.29 OEU22499.1 - 9e-23 81.1 0.2 9.3e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OEU22499.1 - 2.1e-17 63.7 1.1 2.4e-17 63.6 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-U1 PF06220.12 OEU22499.1 - 1 9.2 6.2 2.4 8.0 6.2 1.5 1 0 0 1 1 1 0 U1 zinc finger MoCF_biosynth PF00994.24 OEU22500.1 - 8.7e-29 100.0 0.0 1.5e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 OEU22500.1 - 2.5e-21 76.5 0.0 4.5e-20 72.4 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.32 OEU22501.1 - 2.9e-18 65.9 18.7 2e-05 25.3 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22501.1 - 5.8e-13 49.0 7.6 0.0004 20.6 0.4 5.0 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU22501.1 - 0.0031 17.4 0.2 4.6 7.1 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OEU22501.1 - 0.0088 15.0 0.4 0.043 12.8 0.1 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HTH_Tnp_1 PF01527.20 OEU22501.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase GOLD_2 PF13897.6 OEU22502.1 - 0.34 11.4 7.7 1.1 9.8 0.0 2.9 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Arm PF00514.23 OEU22503.1 - 3.5e-95 309.5 19.1 1.3e-12 47.2 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OEU22503.1 - 5.8e-29 100.1 3.5 3.1e-10 40.3 0.0 6.6 5 2 2 7 7 7 6 HEAT-like repeat HEAT_2 PF13646.6 OEU22503.1 - 5.5e-24 84.4 0.1 3.2e-08 33.9 0.0 5.5 2 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 OEU22503.1 - 2.6e-21 73.9 3.3 0.00018 21.5 0.0 8.3 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.20 OEU22503.1 - 4.7e-21 75.0 0.3 1.8e-20 73.1 0.3 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 OEU22503.1 - 1.6e-18 66.0 2.3 4.4e-18 64.6 2.3 1.8 1 0 0 1 1 1 1 Atypical Arm repeat Arm_2 PF04826.13 OEU22503.1 - 1.8e-09 37.5 0.0 0.0017 17.9 0.0 3.8 1 1 4 5 5 5 2 Armadillo-like Adaptin_N PF01602.20 OEU22503.1 - 1.9e-06 26.8 0.0 0.01 14.4 0.0 2.6 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 OEU22503.1 - 1.9e-06 28.0 0.0 0.096 12.7 0.0 3.8 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 OEU22503.1 - 2.8e-06 27.4 0.0 3.4 7.8 0.0 4.4 4 0 0 4 4 4 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 OEU22503.1 - 0.00026 20.9 0.1 4 7.5 0.2 3.7 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 OEU22503.1 - 0.00029 21.0 1.7 6.4 7.1 0.1 4.5 3 2 2 5 5 5 3 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 OEU22503.1 - 0.00038 20.9 0.6 0.95 10.3 0.1 5.2 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 OEU22503.1 - 0.0017 18.0 0.0 37 3.8 0.0 4.9 2 2 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 OEU22503.1 - 0.0028 17.1 0.0 0.023 14.1 0.0 2.1 1 1 1 2 2 2 1 Mo25-like V-ATPase_H_N PF03224.14 OEU22503.1 - 0.036 13.4 0.0 1.2 8.4 0.0 2.4 1 1 1 2 2 2 0 V-ATPase subunit H Abhydrolase_1 PF00561.20 OEU22504.1 - 3.1e-06 27.0 0.9 1.5e-05 24.8 0.7 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU22504.1 - 0.0017 19.0 0.9 0.0041 17.7 0.6 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cor1 PF04803.12 OEU22504.1 - 0.028 14.6 4.2 0.87 9.8 0.4 2.3 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Hydrolase_4 PF12146.8 OEU22504.1 - 0.052 12.8 0.0 2.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DUF713 PF05218.14 OEU22504.1 - 0.1 12.3 0.3 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Phycobilisome PF00502.19 OEU22504.1 - 0.33 10.9 2.1 1.7 8.6 0.2 2.7 2 1 1 3 3 3 0 Phycobilisome protein Methyltrans_RNA PF04452.14 OEU22505.1 - 3.4e-23 82.2 0.0 1.9e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 RNA methyltransferase PHF5 PF03660.14 OEU22506.1 - 3.3e-50 168.6 13.3 3.7e-50 168.5 13.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OEU22506.1 - 0.015 13.2 7.4 0.016 13.1 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 OEU22506.1 - 1.5 9.2 19.1 0.14 12.5 3.5 2.6 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 OEU22506.1 - 4.2 7.5 16.7 1.5 8.9 3.1 2.9 1 1 1 2 2 2 0 Double zinc ribbon Rav1p_C PF12234.8 OEU22507.1 - 8.6e-33 113.6 0.9 1.4e-32 112.9 0.9 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal SH2 PF00017.24 OEU22507.1 - 0.00096 19.2 0.0 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Methyltransf_21 PF05050.12 OEU22508.1 - 1e-11 45.2 0.0 1.7e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3336 PF11815.8 OEU22509.1 - 2.7e-23 82.2 0.0 6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OEU22509.1 - 3.7e-16 59.9 0.0 7.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PCMT PF01135.19 OEU22510.1 - 1.5e-23 83.7 0.0 2.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DNA_pol_phi PF04931.13 OEU22510.1 - 0.00098 17.4 20.0 0.0015 16.8 20.0 1.2 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 OEU22510.1 - 0.0046 15.2 16.2 0.0058 14.9 16.2 1.1 1 0 0 1 1 1 1 Nop14-like family Methyltransf_31 PF13847.6 OEU22510.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OEU22510.1 - 0.037 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TFIIA PF03153.13 OEU22510.1 - 0.06 13.3 8.5 0.082 12.9 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OEU22510.1 - 0.35 10.2 16.1 0.5 9.6 16.1 1.1 1 0 0 1 1 1 0 BUD22 HA PF03457.14 OEU22511.1 - 2.9e-36 123.6 6.6 6.2e-18 64.9 2.1 2.6 2 0 0 2 2 2 2 Helicase associated domain Peptidase_M41 PF01434.18 OEU22512.1 - 1.1e-60 204.8 4.0 1.6e-60 204.3 4.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OEU22512.1 - 7.2e-42 142.9 0.0 1.6e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU22512.1 - 9.4e-09 35.0 0.0 2.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OEU22512.1 - 1.4e-05 25.4 0.2 0.018 15.3 0.2 3.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU22512.1 - 4.1e-05 24.0 0.1 0.0089 16.4 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 OEU22512.1 - 0.00018 20.9 0.1 0.0006 19.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 OEU22512.1 - 0.00026 21.0 0.1 0.0017 18.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU22512.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OEU22512.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OEU22512.1 - 0.017 15.2 0.6 0.11 12.7 0.0 2.6 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 OEU22512.1 - 0.019 14.3 0.5 0.13 11.6 0.0 2.5 3 0 0 3 3 3 0 KaiC Reprolysin_3 PF13582.6 OEU22512.1 - 0.026 15.0 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2075 PF09848.9 OEU22512.1 - 0.027 13.7 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OEU22512.1 - 0.029 13.9 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OEU22512.1 - 0.032 14.0 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OEU22512.1 - 0.033 13.9 0.9 0.46 10.2 0.1 3.0 2 1 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 OEU22512.1 - 0.038 14.4 0.4 0.19 12.1 0.0 2.5 2 1 1 3 3 2 0 AAA domain Mg_chelatase PF01078.21 OEU22512.1 - 0.039 13.3 0.2 0.082 12.3 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OEU22512.1 - 0.043 13.8 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 OEU22512.1 - 0.06 12.6 0.6 0.2 10.9 0.5 1.8 1 1 1 2 2 2 0 Zeta toxin DUF815 PF05673.13 OEU22512.1 - 0.075 12.2 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 OEU22512.1 - 0.081 12.8 0.2 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 OEU22512.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE hnRNP_Q_AcD PF18360.1 OEU22514.1 - 1.4e-05 24.9 0.1 0.011 15.7 0.0 2.8 3 0 0 3 3 3 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF809 PF05663.11 OEU22514.1 - 0.96 9.6 5.5 0.73 10.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF809) GREB1 PF15782.5 OEU22514.1 - 5.3 4.0 18.8 7.9 3.5 18.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SUIM_assoc PF16619.5 OEU22515.1 - 0.0043 17.1 1.2 0.011 15.8 1.2 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Peptidase_C9 PF01707.16 OEU22515.1 - 0.058 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C9 Androgen_recep PF02166.16 OEU22515.1 - 3.5 6.4 4.9 5.3 5.8 4.9 1.2 1 0 0 1 1 1 0 Androgen receptor Kinesin PF00225.23 OEU22516.1 - 5.4e-59 199.8 0.1 1.1e-58 198.8 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OEU22516.1 - 9.2e-20 71.1 0.0 1.3e-13 51.1 0.0 3.3 2 0 0 2 2 2 2 Microtubule binding CCDC144C PF14915.6 OEU22516.1 - 0.00048 19.3 6.5 0.00048 19.3 6.5 2.6 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region MscS_porin PF12795.7 OEU22516.1 - 0.0083 15.7 7.1 0.0083 15.7 7.1 3.0 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain PI3K_P85_iSH2 PF16454.5 OEU22516.1 - 0.0096 15.5 3.1 0.0096 15.5 3.1 3.8 2 2 2 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Metal_resist PF13801.6 OEU22516.1 - 0.34 11.1 1.2 0.79 9.9 1.2 1.6 1 0 0 1 1 1 0 Heavy-metal resistance Cbl_N PF02262.16 OEU22516.1 - 0.34 10.9 9.2 0.12 12.4 1.6 3.8 4 1 1 5 5 5 0 CBL proto-oncogene N-terminal domain 1 Cortex-I_coil PF09304.10 OEU22516.1 - 6 7.1 23.3 0.4 10.9 3.8 4.1 2 2 1 3 3 3 0 Cortexillin I, coiled coil GST_N_3 PF13417.6 OEU22517.1 - 1.9e-06 28.2 0.0 3.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OEU22517.1 - 0.0018 18.4 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 OEU22517.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-RING_2 PF13639.6 OEU22518.1 - 1.6e-08 34.7 10.8 3.4e-08 33.7 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OEU22518.1 - 4.6e-07 29.8 4.2 9.3e-07 28.8 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OEU22518.1 - 8.2e-06 25.7 1.7 6.7e-05 22.8 0.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 OEU22518.1 - 8.3e-06 25.4 1.3 8.3e-06 25.4 1.3 2.7 4 0 0 4 4 4 1 RING-like zinc finger zf-C3HC4 PF00097.25 OEU22518.1 - 0.00031 20.6 5.1 0.00064 19.5 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU22518.1 - 0.00049 20.3 8.5 0.00049 20.3 8.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OEU22518.1 - 0.0019 18.0 6.1 0.0044 16.8 6.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OEU22518.1 - 0.07 13.0 7.1 0.14 12.0 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU22518.1 - 0.087 12.8 5.3 0.21 11.6 5.3 1.7 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 OEU22518.1 - 0.13 12.4 6.8 0.42 10.8 6.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OEU22518.1 - 0.47 10.4 11.5 5.1 7.1 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PI3K_1B_p101 PF10486.9 OEU22519.1 - 0.11 10.3 1.2 0.13 10.0 1.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3727 PF12527.8 OEU22519.1 - 0.23 11.7 3.7 0.42 10.9 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) NOA36 PF06524.12 OEU22519.1 - 5.5 6.2 10.9 11 5.2 10.9 1.5 1 0 0 1 1 1 0 NOA36 protein Hist_deacetyl PF00850.19 OEU22520.1 - 5.4e-80 269.1 0.3 6.7e-80 268.8 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Myb_DNA-binding PF00249.31 OEU22521.1 - 0.0048 17.1 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU22521.1 - 0.024 14.5 0.2 0.031 14.2 0.2 1.2 1 0 0 1 1 1 0 Myb DNA-binding like HABP4_PAI-RBP1 PF04774.15 OEU22522.1 - 1.9e-13 51.2 11.4 1.9e-13 51.2 11.4 3.4 2 1 2 4 4 4 1 Hyaluronan / mRNA binding family Keratin_2_head PF16208.5 OEU22522.1 - 1.3 9.1 18.4 0.062 13.4 11.9 1.8 2 0 0 2 2 2 0 Keratin type II head DUF4250 PF14056.6 OEU22524.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) CDP-OH_P_transf PF01066.21 OEU22525.1 - 1.8e-12 47.9 0.1 1.8e-12 47.9 0.1 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ima1_N PF09779.9 OEU22526.1 - 0.15 12.9 0.2 0.36 11.7 0.2 1.6 1 0 0 1 1 1 0 Ima1 N-terminal domain PhzC-PhzF PF02567.16 OEU22527.1 - 3.1e-33 115.5 0.0 8.7e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 OEU22527.1 - 4.4e-07 30.1 0.0 9.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU22527.1 - 5.7e-05 23.5 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU22527.1 - 0.0052 16.7 0.1 0.018 15.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU22527.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase VMA21 PF09446.10 OEU22529.1 - 9.5e-11 41.6 1.2 1.4e-10 41.1 1.2 1.3 1 0 0 1 1 1 1 VMA21-like domain Peptidase_A8 PF01252.18 OEU22530.1 - 0.033 14.4 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Signal peptidase (SPase) II Mur_ligase_M PF08245.12 OEU22531.1 - 1.1e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OEU22531.1 - 0.0048 17.1 0.0 0.026 14.8 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain NTPase_1 PF03266.15 OEU22531.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 NTPase NAD_binding_1 PF00175.21 OEU22531.1 - 0.11 13.2 0.1 1.1 9.9 0.1 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain SASA PF03629.18 OEU22534.1 - 2e-14 53.8 0.1 3.7e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Aminotran_1_2 PF00155.21 OEU22535.1 - 1.8e-35 122.8 0.0 2.3e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OEU22535.1 - 0.002 16.7 0.0 0.0051 15.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OEU22535.1 - 0.0026 17.1 0.1 0.53 9.5 0.1 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 OEU22535.1 - 0.0062 15.3 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OEU22535.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF383 PF04063.14 OEU22536.1 - 0.017 14.8 0.0 0.099 12.3 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF383) Fzo_mitofusin PF04799.13 OEU22537.1 - 0.018 14.6 2.9 0.018 14.6 2.9 2.1 1 1 1 2 2 2 0 fzo-like conserved region DLP_helical PF18709.1 OEU22537.1 - 0.041 13.1 6.4 1.2 8.2 0.8 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain RYDR_ITPR PF01365.21 OEU22537.1 - 0.37 10.2 8.3 0.76 9.2 8.2 1.5 1 1 0 1 1 1 0 RIH domain Nup88 PF10168.9 OEU22537.1 - 1.3 6.7 11.9 1.5 6.5 11.9 1.1 1 0 0 1 1 1 0 Nuclear pore component EMP70 PF02990.16 OEU22538.1 - 3.8e-177 590.1 5.8 4.8e-177 589.8 5.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 IATP PF04568.12 OEU22538.1 - 0.082 13.3 0.4 0.16 12.4 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF753 PF05444.12 OEU22539.1 - 0.96 9.4 10.8 1.7 8.6 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF753) MFAP1 PF06991.11 OEU22540.1 - 1.1e-39 136.5 23.6 1.1e-39 136.5 23.6 3.8 2 1 2 4 4 4 1 Microfibril-associated/Pre-mRNA processing DUF2839 PF10999.8 OEU22540.1 - 6.5 7.2 6.1 0.79 10.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Pkinase PF00069.25 OEU22541.1 - 8.1e-30 104.1 0.0 1e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22541.1 - 5.1e-26 91.5 0.0 5.6e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU22541.1 - 0.0017 18.4 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family UbiA PF01040.18 OEU22543.1 - 8.5e-35 120.2 11.6 2.3e-34 118.8 11.6 1.8 1 1 0 1 1 1 1 UbiA prenyltransferase family DEAD PF00270.29 OEU22544.1 - 9.6e-28 97.1 0.3 1.8e-26 92.9 0.3 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU22544.1 - 3.3e-15 56.4 0.2 2.1e-14 53.8 0.2 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22544.1 - 1.8e-05 24.8 0.0 6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 OEU22544.1 - 0.033 13.7 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein SnoaL_3 PF13474.6 OEU22545.1 - 6.1e-17 62.0 1.1 9.1e-17 61.4 0.4 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 OEU22545.1 - 2.8e-06 27.7 0.4 3.5e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) UVR PF02151.19 OEU22545.1 - 0.00019 21.1 0.8 0.00049 19.8 0.8 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif SnoaL_2 PF12680.7 OEU22545.1 - 0.0025 18.4 0.0 0.0072 16.9 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain Rrp44_CSD1 PF17216.3 OEU22545.1 - 1.4 8.6 5.8 1.2 8.8 2.9 2.1 2 0 0 2 2 2 0 Rrp44-like cold shock domain AMMECR1 PF01871.17 OEU22546.1 - 5.9e-43 146.4 0.0 6.6e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DER1 PF04511.15 OEU22547.1 - 6.2e-30 104.6 5.6 7e-30 104.4 5.6 1.0 1 0 0 1 1 1 1 Der1-like family LAB_N PF07578.11 OEU22547.1 - 0.00064 19.8 0.9 0.0012 18.9 0.9 1.4 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain adh_short_C2 PF13561.6 OEU22548.1 - 4.7e-53 180.1 1.1 8.5e-52 176.0 1.1 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU22548.1 - 3.8e-47 160.3 1.9 3.3e-46 157.2 1.9 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU22548.1 - 1.9e-13 50.7 1.6 8e-11 42.2 1.6 2.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OEU22548.1 - 2.5e-06 27.1 0.0 5.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU22548.1 - 5e-06 26.2 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OEU22548.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OEU22548.1 - 0.0019 17.2 0.0 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 OEU22548.1 - 0.01 16.2 0.1 0.021 15.3 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 OEU22548.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCMT PF01135.19 OEU22548.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2-Hacid_dh_C PF02826.19 OEU22548.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OEU22548.1 - 0.029 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 OEU22548.1 - 0.034 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_25 PF13649.6 OEU22548.1 - 0.036 14.8 0.0 0.072 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OEU22548.1 - 0.038 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Baculo_Y142 PF04913.12 OEU22548.1 - 0.068 11.8 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein RmlD_sub_bind PF04321.17 OEU22548.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_23 PF13489.6 OEU22548.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DnaB_C PF03796.15 OEU22549.1 - 0.0001 21.8 1.5 0.00015 21.2 0.2 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Integrase_1 PF12835.7 OEU22549.1 - 0.045 13.9 1.0 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Integrase AAA_25 PF13481.6 OEU22549.1 - 0.05 13.2 0.2 0.79 9.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain Hypoth_Ymh PF09509.10 OEU22549.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) CitMHS_2 PF16980.5 OEU22550.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative citrate transport Coatomer_WDAD PF04053.14 OEU22551.1 - 5.6e-140 467.3 0.0 2.8e-139 465.0 0.0 2.1 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 OEU22551.1 - 3.3e-38 129.0 8.5 3.8e-07 30.7 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22551.1 - 1.6e-06 28.3 0.0 1.4 9.3 0.0 5.3 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OEU22551.1 - 0.12 11.0 1.8 9.2 4.8 0.0 4.0 3 2 2 5 5 5 0 Nucleoporin Nup120/160 HA PF03457.14 OEU22552.1 - 0.11 12.9 0.1 1 9.7 0.1 2.1 1 1 0 1 1 1 0 Helicase associated domain LSM PF01423.22 OEU22553.1 - 4.2e-13 48.8 0.3 6.5e-13 48.2 0.3 1.3 1 1 0 1 1 1 1 LSM domain ERCC3_RAD25_C PF16203.5 OEU22554.1 - 2.1e-106 354.7 0.1 3.9e-106 353.8 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OEU22554.1 - 1.6e-36 125.2 0.0 3.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22554.1 - 2.8e-16 60.0 0.0 6.2e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OEU22554.1 - 5.4e-11 42.8 0.1 2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OEU22554.1 - 3.6e-09 35.8 0.5 9.2e-09 34.5 0.5 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 OEU22554.1 - 0.05 13.3 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 SWI2/SNF2 ATPase BUD22 PF09073.10 OEU22556.1 - 0.029 13.7 7.4 0.042 13.2 7.4 1.2 1 0 0 1 1 1 0 BUD22 Afi1 PF07792.12 OEU22556.1 - 4.3 7.8 12.5 4.6 7.7 6.8 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3439 PF11921.8 OEU22556.1 - 4.6 7.2 13.9 1.3 9.0 6.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF2956 PF11169.8 OEU22556.1 - 6.8 6.9 7.5 2.5 8.4 0.1 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2956) DUF1980 PF09323.10 OEU22556.1 - 7.2 6.5 5.9 3.4 7.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DNA_pol_phi PF04931.13 OEU22556.1 - 8.6 4.3 13.2 14 3.6 13.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi IGPS PF00218.21 OEU22557.1 - 3.3e-25 88.7 0.1 4.5e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 OEU22557.1 - 0.00022 20.8 1.7 0.08 12.4 0.0 3.7 3 1 0 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.18 OEU22557.1 - 0.0059 15.7 0.5 0.0099 14.9 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OEU22557.1 - 0.065 12.2 3.2 0.08 11.9 0.1 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain THOC2_N PF16134.5 OEU22557.1 - 4.4 5.8 5.4 5.6 5.5 5.4 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF645 PF04875.12 OEU22558.1 - 0.054 13.5 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF645 VEFS-Box PF09733.9 OEU22558.1 - 0.1 12.4 0.3 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 VEFS-Box of polycomb protein DUF4271 PF14093.6 OEU22559.1 - 0.00058 19.8 1.6 0.00076 19.5 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Ndc1_Nup PF09531.10 OEU22559.1 - 0.084 11.6 4.3 0.11 11.2 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNase_T PF00929.24 OEU22560.1 - 6.5e-06 26.8 0.2 5.7e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 Exonuclease zf-CCCH_4 PF18044.1 OEU22560.1 - 0.00058 19.6 0.8 0.0011 18.7 0.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OEU22560.1 - 0.04 13.8 1.2 0.079 12.9 1.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Metallophos_3 PF14582.6 OEU22560.1 - 0.09 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily zf_CCCH_4 PF18345.1 OEU22560.1 - 0.11 12.5 2.7 0.22 11.6 2.7 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 OEU22560.1 - 0.18 12.3 2.4 0.41 11.2 2.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MRP-S25 PF13741.6 OEU22561.1 - 0.053 13.1 0.2 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 Band_7 PF01145.25 OEU22562.1 - 9.4e-07 29.0 9.0 5e-06 26.6 9.0 2.0 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7 PF01145.25 OEU22563.1 - 8.4e-12 45.4 0.0 1.8e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DivIVA PF05103.13 OEU22563.1 - 0.072 13.2 8.2 0.14 12.2 8.2 1.5 1 0 0 1 1 1 0 DivIVA protein SNF2_N PF00176.23 OEU22565.1 - 4.4e-42 144.0 0.0 7.4e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU22565.1 - 2.7e-17 63.1 0.0 9.8e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22565.1 - 9e-10 38.8 0.0 1.1e-08 35.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OEU22565.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase TniB PF05621.11 OEU22565.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein RHH_8 PF17723.1 OEU22565.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family ETF PF01012.21 OEU22566.1 - 2.3e-47 161.3 0.0 3e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain YnfE PF17452.2 OEU22566.1 - 0.08 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized YnfE-like Chloroa_b-bind PF00504.21 OEU22567.1 - 8.9e-39 133.6 0.1 1.1e-38 133.4 0.1 1.0 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Terminase_3 PF04466.13 OEU22568.1 - 0.021 14.4 3.8 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 Phage terminase large subunit Complex1_LYR PF05347.15 OEU22568.1 - 0.21 11.6 2.9 0.52 10.4 0.1 2.8 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Aldo_ket_red PF00248.21 OEU22569.1 - 1.5e-42 145.9 0.0 1.8e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family T3SSipB PF16535.5 OEU22569.1 - 0.099 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB Myb_DNA-binding PF00249.31 OEU22570.1 - 4.3e-11 42.8 0.0 3.6e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 OEU22570.1 - 1.3e-08 34.5 6.6 2.2e-08 33.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OEU22570.1 - 4.8e-07 29.9 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ACT_6 PF13740.6 OEU22570.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF2054 PF10218.9 OEU22570.1 - 1.8 8.7 6.4 3.8 7.6 3.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) DUF4239 PF14023.6 OEU22571.1 - 2.4e-53 181.0 0.1 3.4e-53 180.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Rx_N PF18052.1 OEU22574.1 - 0.0021 18.3 0.5 0.0021 18.3 0.5 2.1 2 0 0 2 2 2 1 Rx N-terminal domain DUF5344 PF17279.2 OEU22574.1 - 0.021 15.4 4.5 0.021 15.4 4.5 3.0 2 1 2 4 4 4 0 Family of unknown function (DUF5344) SNARE PF05739.19 OEU22574.1 - 0.037 14.0 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 SNARE domain MtN3_slv PF03083.16 OEU22575.1 - 4.2e-31 106.8 16.5 6.1e-16 58.2 1.6 2.9 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF2070 PF09843.9 OEU22575.1 - 3.6 5.8 9.0 4.7 5.4 9.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATP-grasp_4 PF13535.6 OEU22576.1 - 9.4e-26 90.3 0.0 4.6e-14 52.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 OEU22576.1 - 4.3e-21 75.6 0.0 1.2e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 OEU22576.1 - 2.3e-19 69.9 0.3 5.3e-08 32.8 0.0 3.6 3 2 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAL_C2 PF18603.1 OEU22576.1 - 1.3e-08 34.8 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 OEU22576.1 - 5.9e-08 32.5 0.0 0.0055 16.5 0.0 3.8 2 2 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 OEU22576.1 - 6.4e-07 29.1 0.0 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Fasciclin PF02469.22 OEU22577.1 - 2.2e-17 63.4 0.0 5.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Fasciclin domain DUF1325 PF07039.11 OEU22577.1 - 4e-12 46.4 0.1 3.7e-11 43.2 0.1 2.4 2 0 0 2 2 2 1 SGF29 tudor-like domain Metallophos PF00149.28 OEU22577.1 - 0.0089 16.5 4.4 2.2 8.8 1.4 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase LEA_6 PF10714.9 OEU22577.1 - 0.23 11.5 1.9 40 4.3 0.6 3.9 3 0 0 3 3 3 0 Late embryogenesis abundant protein 18 DDHD PF02862.17 OEU22577.1 - 1.1 9.4 14.4 0.72 10.0 0.2 3.7 4 0 0 4 4 4 0 DDHD domain PPR_2 PF13041.6 OEU22578.1 - 2.9e-21 75.4 4.0 3.3e-06 27.2 1.4 7.0 5 3 2 7 7 7 4 PPR repeat family PPR_1 PF12854.7 OEU22578.1 - 1e-19 69.9 0.0 0.0081 15.8 0.0 8.2 9 0 0 9 9 9 4 PPR repeat PPR_3 PF13812.6 OEU22578.1 - 1.7e-15 56.8 0.9 0.00019 21.4 0.0 6.6 5 2 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 OEU22578.1 - 9.8e-08 31.7 11.7 0.51 10.7 0.0 8.0 8 1 0 8 8 8 3 PPR repeat PPR_long PF17177.4 OEU22578.1 - 8.9e-06 25.2 2.0 0.14 11.5 0.1 3.1 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP Nipped-B_C PF12830.7 OEU22578.1 - 0.01 15.8 6.2 0.13 12.2 0.5 3.4 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 OEU22578.1 - 0.073 11.6 0.4 0.28 9.7 0.1 2.0 2 1 1 3 3 3 0 Adaptin N terminal region SpmSyn_N PF17950.1 OEU22578.1 - 0.18 12.0 0.2 3.7 7.8 0.0 2.7 3 0 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal Chloroa_b-bind PF00504.21 OEU22579.1 - 8e-32 111.0 0.0 1.1e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DOT1 PF08123.13 OEU22580.1 - 0.003 17.1 0.0 0.0092 15.5 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 IQ PF00612.27 OEU22581.1 - 3.3e-05 23.3 7.7 0.0004 19.9 1.0 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif Chloroa_b-bind PF00504.21 OEU22582.1 - 4.7e-32 111.8 0.0 5.7e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4148 PF13663.6 OEU22582.1 - 1.2 9.4 3.3 2 8.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Peptidase_S26 PF10502.9 OEU22583.1 - 2.3e-11 43.6 0.0 3.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OEU22583.1 - 9.1e-09 35.2 0.2 3.9e-08 33.1 0.2 2.0 1 1 0 1 1 1 1 Peptidase S24-like CSG2 PF16965.5 OEU22583.1 - 0.053 12.5 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator PYC_OADA PF02436.18 OEU22583.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Chloroa_b-bind PF00504.21 OEU22584.1 - 9.7e-29 101.0 0.1 1.3e-28 100.6 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ni_hydr_CYTB PF01292.20 OEU22584.1 - 0.0025 17.4 0.1 1.9 8.0 0.0 2.1 2 0 0 2 2 2 2 Prokaryotic cytochrome b561 Helicase_C_2 PF13307.6 OEU22585.1 - 2.5e-52 177.5 0.0 5.4e-52 176.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OEU22585.1 - 2e-46 157.8 0.0 3.7e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OEU22585.1 - 3e-07 30.6 0.0 0.00033 20.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU22585.1 - 0.00063 19.6 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 OEU22585.1 - 0.00097 18.0 0.0 0.0031 16.3 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain HBB PF06777.11 OEU22585.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Helical and beta-bridge domain PhoH PF02562.16 OEU22585.1 - 0.015 14.8 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein HSF_DNA-bind PF00447.17 OEU22586.1 - 9.8e-23 80.6 0.5 1.5e-22 80.0 0.2 1.5 2 0 0 2 2 2 1 HSF-type DNA-binding Agenet PF05641.12 OEU22587.1 - 0.00035 21.0 0.0 0.0013 19.1 0.0 2.0 2 0 0 2 2 2 1 Agenet domain TUDOR_5 PF18359.1 OEU22587.1 - 0.0041 16.8 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 OEU22587.1 - 0.13 12.3 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Cyclin_N PF00134.23 OEU22588.1 - 4.8e-07 29.6 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU22588.1 - 0.0065 16.5 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 OEU22588.1 - 0.11 12.6 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Na_H_Exchanger PF00999.21 OEU22589.1 - 3e-07 29.6 2.2 3.8e-07 29.2 2.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ABC_tran PF00005.27 OEU22590.1 - 4.9e-40 137.2 0.0 1.7e-19 70.7 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OEU22590.1 - 3.7e-18 66.4 0.3 0.0023 17.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OEU22590.1 - 6.4e-11 42.1 0.0 0.0022 17.5 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OEU22590.1 - 5.9e-09 36.7 1.1 0.0033 17.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 OEU22590.1 - 9.6e-08 32.4 0.1 0.0047 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OEU22590.1 - 6.4e-07 29.0 0.6 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OEU22590.1 - 7e-07 29.3 0.1 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OEU22590.1 - 5.7e-06 26.3 0.0 0.063 13.0 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 OEU22590.1 - 1.2e-05 25.3 0.1 0.072 13.0 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 OEU22590.1 - 4.1e-05 23.4 0.1 0.22 11.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 OEU22590.1 - 4.7e-05 23.4 0.9 0.25 11.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 OEU22590.1 - 0.0001 22.5 1.0 0.37 11.0 0.0 2.8 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OEU22590.1 - 0.00011 22.0 0.9 0.53 10.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OEU22590.1 - 0.00017 21.9 0.0 0.66 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 OEU22590.1 - 0.0003 20.8 0.0 0.14 12.0 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OEU22590.1 - 0.00077 19.9 0.0 0.8 10.1 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain NB-ARC PF00931.22 OEU22590.1 - 0.00093 18.5 0.3 0.38 9.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain ATP-synt_ab PF00006.25 OEU22590.1 - 0.00095 18.9 0.2 0.78 9.4 0.1 2.9 2 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 OEU22590.1 - 0.0013 17.6 0.5 0.22 10.3 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Arf PF00025.21 OEU22590.1 - 0.0013 18.2 0.5 0.028 13.9 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_14 PF13173.6 OEU22590.1 - 0.0019 18.3 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OEU22590.1 - 0.0019 18.1 0.6 0.54 10.1 0.1 2.7 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.9 OEU22590.1 - 0.0024 17.7 0.3 1 9.1 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OEU22590.1 - 0.0027 18.0 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OEU22590.1 - 0.0041 17.5 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 OEU22590.1 - 0.0053 14.4 3.8 0.047 11.2 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) DLIC PF05783.11 OEU22590.1 - 0.0055 15.6 0.1 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) RNA_helicase PF00910.22 OEU22590.1 - 0.011 16.1 0.4 5.8 7.3 0.1 2.9 2 1 0 2 2 2 0 RNA helicase TsaE PF02367.17 OEU22590.1 - 0.013 15.5 0.5 1.5 8.9 0.1 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OEU22590.1 - 0.018 15.6 0.1 6 7.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_27 PF13514.6 OEU22590.1 - 0.019 14.6 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OEU22590.1 - 0.022 14.4 2.6 0.6 9.7 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 OEU22590.1 - 0.025 14.5 1.1 1.8 8.5 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Bac_DnaA PF00308.18 OEU22590.1 - 0.026 14.4 0.8 3.7 7.3 0.0 2.9 3 1 0 3 3 3 0 Bacterial dnaA protein T2SSE PF00437.20 OEU22590.1 - 0.041 12.9 1.8 0.95 8.5 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 OEU22590.1 - 0.052 13.6 2.8 1.9 8.6 0.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 OEU22590.1 - 0.058 13.6 0.1 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OEU22590.1 - 0.063 12.8 0.1 8.2 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 OEU22590.1 - 0.064 12.5 0.3 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Ras PF00071.22 OEU22590.1 - 0.073 12.7 0.3 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Ras family DUF2075 PF09848.9 OEU22590.1 - 0.083 12.1 0.3 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 OEU22590.1 - 0.096 12.7 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 OEU22590.1 - 0.1 11.8 0.1 8.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin SRP54 PF00448.22 OEU22590.1 - 0.11 12.1 1.8 7.6 6.1 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FeoB_N PF02421.18 OEU22590.1 - 0.14 11.7 4.5 4.8 6.7 0.1 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B 4HB PF17947.1 OEU22590.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Four helical bundle domain AAA_13 PF13166.6 OEU22590.1 - 0.21 10.2 6.2 0.52 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 OEU22590.1 - 0.28 10.6 0.6 17 4.8 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 OEU22590.1 - 0.35 10.2 1.0 3.4 6.9 0.2 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 OEU22590.1 - 0.58 10.6 4.1 15 6.0 0.1 3.1 3 0 0 3 3 2 0 AAA domain TPR_12 PF13424.6 OEU22591.1 - 1.7e-07 31.4 2.4 0.00042 20.6 0.3 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF913 PF06025.12 OEU22591.1 - 0.2 10.6 7.5 0.25 10.3 7.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 OEU22591.1 - 0.32 10.3 20.0 0.38 10.0 20.0 1.1 1 0 0 1 1 1 0 BUD22 TPR_16 PF13432.6 OEU22591.1 - 0.39 11.4 3.3 0.65 10.7 0.0 2.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C97 PF05903.14 OEU22592.1 - 1.7e-28 99.4 0.0 2.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 OEU22592.1 - 0.02 15.2 0.2 0.037 14.3 0.2 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase NESP55 PF06390.12 OEU22595.1 - 0.094 12.3 17.7 0.24 10.9 3.0 2.6 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 OEU22595.1 - 0.3 11.1 18.2 0.49 10.4 6.5 3.2 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Retrotran_gag_2 PF14223.6 OEU22596.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCCH_4 PF18044.1 OEU22597.1 - 0.17 11.7 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger DUF2239 PF09998.9 OEU22597.1 - 4.3 7.1 5.9 1.4 8.6 2.9 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) RNA_POL_M_15KD PF02150.16 OEU22598.1 - 7.5e-09 35.3 0.8 7.5e-09 35.3 0.8 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 OEU22598.1 - 6.1e-08 32.4 2.1 6.1e-08 32.4 2.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zinc_ribbon_13 PF09855.9 OEU22598.1 - 2.6 8.3 7.2 11 6.2 0.2 2.8 2 1 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ArsA_ATPase PF02374.15 OEU22599.1 - 1.9e-85 286.7 1.7 4.5e-66 223.1 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 OEU22599.1 - 4.6e-22 78.4 0.0 1.8e-09 37.8 0.0 2.8 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OEU22599.1 - 7.8e-21 74.8 7.6 2e-10 40.9 0.9 3.8 3 1 0 3 3 3 2 AAA domain ParA PF10609.9 OEU22599.1 - 1.3e-16 60.8 14.3 4.4e-07 29.6 0.6 3.9 4 0 0 4 4 4 3 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 OEU22599.1 - 1.2e-10 41.3 3.0 0.00021 20.8 0.3 2.6 3 0 0 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OEU22599.1 - 1.8e-10 40.8 6.2 0.00074 19.2 0.3 3.5 4 0 0 4 4 3 2 SRP54-type protein, GTPase domain MeaB PF03308.16 OEU22599.1 - 5.7e-09 35.4 3.6 4.8e-05 22.5 0.1 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 OEU22599.1 - 1.3e-06 28.1 1.2 0.0027 17.2 0.1 2.5 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 OEU22599.1 - 1.6e-06 27.6 3.0 0.013 14.8 0.1 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 OEU22599.1 - 2.3e-06 27.3 7.6 0.0078 15.8 0.2 3.2 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 OEU22599.1 - 5e-06 26.4 0.1 0.0061 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 OEU22599.1 - 6.9e-06 25.7 0.2 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.17 OEU22599.1 - 2.5e-05 24.1 0.1 0.063 13.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein VirC1 PF07015.11 OEU22599.1 - 0.00014 21.2 2.1 0.062 12.6 0.3 3.2 4 0 0 4 4 4 1 VirC1 protein MipZ PF09140.11 OEU22599.1 - 0.0002 20.7 9.6 0.014 14.7 0.7 3.8 4 0 0 4 4 4 2 ATPase MipZ AAA_18 PF13238.6 OEU22599.1 - 0.0003 21.3 2.4 0.086 13.4 0.0 3.2 3 1 0 3 3 3 1 AAA domain DUF1611 PF07755.11 OEU22599.1 - 0.00035 19.9 3.9 0.0063 15.8 0.1 2.6 3 0 0 3 3 2 1 Domain of unknown function (DUF1611_C) P-loop domain ATPase PF06745.13 OEU22599.1 - 0.0004 19.8 0.5 0.24 10.7 0.1 2.6 2 1 0 2 2 2 1 KaiC ATP_bind_1 PF03029.17 OEU22599.1 - 0.00046 20.0 2.8 0.37 10.5 0.0 2.6 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OEU22599.1 - 0.0006 20.2 0.6 0.69 10.3 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain MobB PF03205.14 OEU22599.1 - 0.00083 19.3 0.7 3.2 7.6 0.0 3.1 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OEU22599.1 - 0.00091 19.4 0.4 0.88 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 OEU22599.1 - 0.0012 18.6 0.3 0.71 9.6 0.1 2.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 OEU22599.1 - 0.003 17.3 2.3 0.59 9.8 0.1 2.8 3 0 0 3 3 3 1 AAA domain KTI12 PF08433.10 OEU22599.1 - 0.0041 16.6 0.3 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_7 PF12775.7 OEU22599.1 - 0.0043 16.6 0.2 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DnaB_C PF03796.15 OEU22599.1 - 0.0046 16.3 0.8 1.5 8.1 0.0 2.5 3 0 0 3 3 2 1 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 OEU22599.1 - 0.0059 17.0 0.5 2.5 8.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 OEU22599.1 - 0.0069 15.6 2.2 0.81 8.8 0.2 2.6 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 OEU22599.1 - 0.017 15.0 0.7 0.69 9.8 0.1 2.7 3 0 0 3 3 2 0 Adenylylsulphate kinase NTPase_1 PF03266.15 OEU22599.1 - 0.02 14.8 5.9 0.3 11.0 0.3 3.0 3 0 0 3 3 3 0 NTPase CTP_synth_N PF06418.14 OEU22599.1 - 0.023 14.0 7.9 0.35 10.1 0.5 2.7 3 0 0 3 3 3 0 CTP synthase N-terminus Thymidylate_kin PF02223.17 OEU22599.1 - 0.047 13.4 0.1 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase LpxK PF02606.14 OEU22599.1 - 0.052 12.6 8.2 1.6 7.8 0.3 2.9 3 0 0 3 3 3 0 Tetraacyldisaccharide-1-P 4'-kinase PIF1 PF05970.14 OEU22599.1 - 0.053 12.7 2.7 0.41 9.8 0.0 2.9 3 0 0 3 3 3 0 PIF1-like helicase DUF815 PF05673.13 OEU22599.1 - 0.057 12.6 0.1 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 OEU22599.1 - 0.06 13.3 5.7 0.2 11.6 0.2 2.3 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 OEU22599.1 - 0.1 11.7 3.4 1 8.3 0.1 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein RuvB_N PF05496.12 OEU22599.1 - 0.11 12.3 0.6 6.6 6.5 0.0 3.0 3 1 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain PRK PF00485.18 OEU22599.1 - 0.17 11.6 2.1 7.3 6.3 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 OEU22599.1 - 0.39 10.6 4.5 3.8 7.4 0.1 2.6 3 0 0 3 3 2 0 RsgA GTPase AAA PF00004.29 OEU22599.1 - 0.41 11.1 3.6 9.5 6.7 0.0 3.2 3 1 1 4 4 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OEU22599.1 - 0.58 9.3 2.0 0.96 8.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 OEU22599.1 - 0.58 10.2 1.8 33 4.5 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OEU22599.1 - 0.94 9.7 3.0 30 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OEU22599.1 - 1.1 9.5 4.8 13 6.0 0.9 2.6 2 0 0 2 2 2 0 AAA domain Glycos_transf_3 PF00591.21 OEU22599.1 - 3 7.4 8.4 1.6 8.3 0.9 2.5 3 0 0 3 3 2 0 Glycosyl transferase family, a/b domain Phage_GPL PF05926.11 OEU22601.1 - 0.061 13.3 2.8 1.2 9.1 1.1 2.5 2 0 0 2 2 2 0 Phage head completion protein (GPL) OxoDH_E1alpha_N PF12573.8 OEU22601.1 - 0.09 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal RVT_2 PF07727.14 OEU22602.1 - 0.0054 16.4 0.1 0.0062 16.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-SNARE_C PF12352.8 OEU22604.1 - 1.6e-05 25.1 0.1 1.6e-05 25.1 0.1 3.0 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Fascin PF06268.13 OEU22604.1 - 0.0048 17.1 0.2 0.011 15.9 0.2 1.7 1 0 0 1 1 1 1 Fascin domain AFP_2 PF18815.1 OEU22604.1 - 0.1 12.9 1.4 0.17 12.1 0.2 2.0 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat S1 PF00575.23 OEU22606.1 - 1.7e-23 82.7 5.9 7.2e-18 64.7 0.1 3.1 2 1 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 OEU22606.1 - 0.012 15.7 0.1 0.7 10.0 0.0 2.9 2 1 0 2 2 2 0 S1 domain LZ_Tnp_IS66 PF13007.7 OEU22606.1 - 0.2 12.4 4.0 1.1 10.1 0.1 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF4769 PF15992.5 OEU22606.1 - 0.31 10.8 0.5 0.55 10.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) DUF5600 PF18150.1 OEU22607.1 - 1.1e-32 112.8 0.1 2.2e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 OEU22607.1 - 2.2e-15 57.1 0.0 3.1e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 OEU22607.1 - 8.4e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 OEU22607.1 - 1.8e-09 37.7 0.0 4.5e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OEU22607.1 - 0.0018 17.8 0.1 0.26 10.8 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 OEU22607.1 - 0.011 16.0 0.0 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OEU22607.1 - 0.04 13.2 0.0 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 AIG1 family Gtr1_RagA PF04670.12 OEU22607.1 - 0.052 12.9 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OEU22607.1 - 0.053 13.4 0.1 21 5.0 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase Synaptobrevin PF00957.21 OEU22608.1 - 6.4e-17 61.1 1.8 6.4e-17 61.1 1.8 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 OEU22608.1 - 3.2e-12 46.3 0.0 5.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sigma_reg_N PF13800.6 OEU22609.1 - 0.0063 16.8 1.3 0.013 15.7 1.3 1.6 1 0 0 1 1 1 1 Sigma factor regulator N-terminal Mid2 PF04478.12 OEU22609.1 - 7.1 6.5 8.1 0.61 9.9 1.6 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Cyclin PF08613.11 OEU22611.1 - 8.6e-09 36.0 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OEU22611.1 - 1.4e-08 34.5 1.0 2.7e-08 33.6 1.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain ELFV_dehydrog PF00208.21 OEU22611.1 - 0.069 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase COPI_assoc PF08507.10 OEU22612.1 - 3.1e-07 30.5 7.7 4.7e-07 29.9 7.7 1.3 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 OEU22612.1 - 0.00026 21.3 7.8 0.00037 20.8 7.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Frag1 PF10277.9 OEU22612.1 - 0.013 15.0 1.7 0.018 14.6 1.7 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Phage_holin_3_6 PF07332.11 OEU22612.1 - 0.092 12.8 3.2 3.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PorA PF11271.8 OEU22612.1 - 0.25 10.6 0.8 1.3 8.3 0.8 1.9 1 1 0 1 1 1 0 Porin PorA Neurensin PF14927.6 OEU22612.1 - 2.4 7.9 6.0 0.89 9.3 0.1 2.5 2 1 0 2 2 2 0 Neurensin DUF3185 PF11381.8 OEU22612.1 - 5.5 7.1 9.5 2.2 8.3 2.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) Evr1_Alr PF04777.13 OEU22613.1 - 8.2e-17 61.5 0.1 2.6e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 OEU22613.1 - 1.9e-11 43.8 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 OEU22613.1 - 0.46 10.6 3.7 1.8 8.7 0.2 2.8 3 0 0 3 3 3 0 Thioredoxin Mo25 PF08569.11 OEU22615.1 - 9.5e-50 169.8 4.8 2.4e-47 161.9 4.8 2.0 1 1 0 1 1 1 1 Mo25-like Neur_chan_memb PF02932.16 OEU22616.1 - 2 8.4 3.6 2.8 8.0 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LCAT PF02450.15 OEU22617.1 - 1.7e-68 231.6 0.0 7.7e-68 229.4 0.0 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 OEU22617.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pro_isomerase PF00160.21 OEU22618.1 - 3.5e-28 98.9 0.1 4.3e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lung_7-TM_R PF06814.13 OEU22619.1 - 1.9e-35 122.6 16.9 2.5e-35 122.2 16.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor LCIB_C_CA PF18599.1 OEU22620.1 - 1.1e-65 221.1 0.0 1.4e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FAD_binding_4 PF01565.23 OEU22621.1 - 3.1e-23 82.1 4.1 5.3e-23 81.3 4.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OEU22621.1 - 4.2e-08 33.2 0.0 8.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like VPS13 PF16908.5 OEU22623.1 - 6.9e-34 117.7 0.4 2e-33 116.1 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 OEU22623.1 - 1.8e-23 83.3 0.0 6.6e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 OEU22623.1 - 1.5e-12 47.6 0.1 9.4e-12 45.1 0.1 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 OEU22623.1 - 8.6e-07 28.6 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Repeating coiled region of VPS13 DGF-1_4 PF11024.8 OEU22623.1 - 3 8.7 7.6 1 10.2 0.8 3.4 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 zinc_ribbon_10 PF10058.9 OEU22624.1 - 0.0028 17.4 0.3 0.0085 15.8 0.3 1.8 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4364 PF14277.6 OEU22624.1 - 0.01 15.6 0.1 0.2 11.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) Ku_PK_bind PF08785.11 OEU22624.1 - 0.071 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Ku C terminal domain like Collagen PF01391.18 OEU22625.1 - 1.2e-05 25.0 0.8 3.6e-05 23.4 0.8 1.8 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Rsm1 PF08600.10 OEU22625.1 - 0.01 15.9 0.2 0.33 11.1 0.0 2.7 2 0 0 2 2 2 0 Rsm1-like Exonuc_VII_L PF02601.15 OEU22625.1 - 0.033 13.8 0.4 1.7 8.1 1.6 2.4 2 1 0 3 3 3 0 Exonuclease VII, large subunit HMA PF00403.26 OEU22625.1 - 0.21 12.0 0.1 0.75 10.3 0.1 1.9 1 0 0 1 1 1 0 Heavy-metal-associated domain BSMAP PF12280.8 OEU22625.1 - 0.5 10.6 3.6 0.71 10.0 0.1 2.6 2 0 0 2 2 2 0 Brain specific membrane anchored protein HAUS2 PF15003.6 OEU22625.1 - 0.55 9.9 4.2 1 9.0 4.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Peptidase_C58 PF03543.14 OEU22625.1 - 0.75 9.5 9.1 1.6 8.4 9.1 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen OmpH PF03938.14 OEU22625.1 - 6.7 7.1 19.2 0.048 14.0 10.3 2.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) His_Phos_1 PF00300.22 OEU22626.1 - 4.6e-05 23.2 0.0 0.011 15.4 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MTTB PF06253.11 OEU22626.1 - 0.17 9.9 0.0 0.22 9.5 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Glyco_trans_1_4 PF13692.6 OEU22627.1 - 6e-07 30.0 0.0 1.6e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OEU22627.1 - 2.2e-06 27.3 0.0 9.4e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OEU22627.1 - 0.00021 21.3 0.1 0.00062 19.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 OEU22627.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Aa_trans PF01490.18 OEU22628.1 - 4.1e-48 164.1 37.2 1e-46 159.5 37.2 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OEU22628.1 - 1.3e-05 24.4 37.8 0.0019 17.3 37.1 2.9 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Mito_carr PF00153.27 OEU22629.1 - 2e-64 213.5 9.6 6.3e-23 80.5 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein RETICULATA-like PF11891.8 OEU22629.1 - 0.013 15.4 0.7 3 7.6 0.1 3.3 3 0 0 3 3 3 0 Protein RETICULATA-related Ribosomal_S15 PF00312.22 OEU22630.1 - 3.6e-28 97.6 2.2 3.9e-28 97.5 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RST PF12174.8 OEU22630.1 - 0.039 13.9 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain HTH_56 PF18662.1 OEU22630.1 - 0.061 13.4 0.3 0.096 12.8 0.3 1.3 1 1 0 1 1 1 0 Cch helix turn helix domain Carbam_trans_C PF16861.5 OEU22631.1 - 2.9e-66 222.2 0.0 3.8e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 OEU22631.1 - 5.8e-17 62.4 0.0 1e-16 61.6 0.0 1.4 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Sec1 PF00995.23 OEU22632.1 - 7.4e-108 362.2 0.0 8.4e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Leu_Phe_trans PF03588.14 OEU22633.1 - 1e-26 93.5 0.0 1e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase 6PF2K PF01591.18 OEU22634.1 - 1.2e-61 207.9 0.8 4.9e-33 114.3 1.9 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OEU22634.1 - 5.6e-19 68.6 0.0 1.8e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OEU22634.1 - 1.3e-05 25.4 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 OEU22634.1 - 0.021 14.3 1.0 0.56 9.6 0.0 2.5 2 1 1 3 3 3 0 Chromatin associated protein KTI12 EMP24_GP25L PF01105.24 OEU22634.1 - 0.028 14.4 0.3 0.049 13.6 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_22 PF13401.6 OEU22634.1 - 0.063 13.5 0.0 0.49 10.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF2116 PF09889.9 OEU22636.1 - 0.045 13.7 0.2 30 4.7 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.32 OEU22637.1 - 0.0092 16.8 0.2 3.3 8.7 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat NTP_transf_2 PF01909.23 OEU22639.1 - 0.0083 16.4 0.9 0.046 14.0 0.0 2.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OEU22639.1 - 0.052 13.8 0.0 0.22 11.8 0.0 2.1 1 0 0 1 1 1 0 Cid1 family poly A polymerase FF PF01846.19 OEU22640.1 - 1.8e-27 95.3 7.0 1.1e-07 31.8 0.6 5.1 5 0 0 5 5 5 3 FF domain WW PF00397.26 OEU22640.1 - 3.1e-05 23.9 0.2 3.1e-05 23.9 0.2 4.1 3 1 0 3 3 3 1 WW domain TetR_C_21 PF17926.1 OEU22640.1 - 0.16 12.1 0.1 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-Tim10_DDP PF02953.15 OEU22641.1 - 3.6e-16 58.6 1.0 3.6e-16 58.6 1.0 2.1 2 0 0 2 2 2 1 Tim10/DDP family zinc finger NAD_binding_10 PF13460.6 OEU22642.1 - 2.3e-12 47.2 0.1 0.00016 21.7 0.0 3.2 2 1 0 2 2 2 2 NAD(P)H-binding NAD_binding_4 PF07993.12 OEU22642.1 - 0.0012 18.1 0.1 1.2 8.2 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 OEU22642.1 - 0.0018 17.9 0.1 0.0042 16.7 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OEU22642.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Herpes_UL7 PF01677.16 OEU22644.1 - 0.02 14.6 0.1 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL7 like His_Me_b4a2 PF18275.1 OEU22644.1 - 0.11 12.6 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain zf-C3HC4 PF00097.25 OEU22646.1 - 2.2e-05 24.2 11.3 3.8e-05 23.5 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OEU22646.1 - 9.7e-05 22.6 13.9 0.00016 22.0 13.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OEU22646.1 - 0.00047 20.0 12.4 0.00078 19.3 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU22646.1 - 0.001 18.8 12.1 0.0017 18.1 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU22646.1 - 0.0035 17.6 10.2 0.0079 16.5 10.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OEU22646.1 - 0.0036 17.2 11.6 0.013 15.5 11.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU22646.1 - 0.0043 16.9 12.0 0.0086 15.9 12.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OEU22646.1 - 0.006 16.6 9.3 0.012 15.7 9.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OEU22646.1 - 1 9.6 10.8 2.2 8.5 10.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Lipase_GDSL_2 PF13472.6 OEU22647.1 - 1.9e-22 80.5 0.0 2.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU22647.1 - 1.5e-14 54.5 0.0 1.9e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OEU22647.1 - 0.11 12.7 0.0 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Actin PF00022.19 OEU22648.1 - 2.1e-49 168.3 0.0 1.3e-48 165.7 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OEU22648.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 MreB/Mbl protein HCO3_cotransp PF00955.21 OEU22649.1 - 5.6e-111 371.9 11.9 9.8e-62 209.4 1.0 2.2 1 1 1 2 2 2 2 HCO3- transporter family CENP-F_N PF10481.9 OEU22649.1 - 1.6 8.3 5.7 2.7 7.5 5.7 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain AAA PF00004.29 OEU22650.1 - 1.7e-36 125.5 0.0 2.2e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU22650.1 - 1.8e-06 28.4 0.1 0.022 15.1 0.2 2.3 1 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 OEU22650.1 - 7.1e-05 22.5 0.2 0.00017 21.4 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OEU22650.1 - 0.00033 20.7 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OEU22650.1 - 0.00048 20.3 0.0 0.00095 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OEU22650.1 - 0.0077 16.0 0.0 0.027 14.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OEU22650.1 - 0.02 15.1 1.2 1 9.6 1.2 2.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OEU22650.1 - 0.051 13.3 0.1 5.3 6.7 0.1 2.4 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 OEU22650.1 - 0.095 12.9 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 OEU22650.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain CbiA PF01656.23 OEU22650.1 - 0.19 11.8 0.4 0.24 11.5 0.4 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 OEU22650.1 - 0.2 11.1 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Ad_cyc_g-alpha PF08509.11 OEU22650.1 - 0.22 11.3 1.4 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Bromodomain PF00439.25 OEU22651.1 - 5.6e-18 64.8 0.2 6e-18 64.7 0.2 1.0 1 0 0 1 1 1 1 Bromodomain Indigoidine_A PF04227.12 OEU22653.1 - 1.3e-112 375.9 2.0 1.5e-112 375.7 2.0 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Mucin PF01456.17 OEU22654.1 - 0.13 12.3 23.2 1.1 9.2 14.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 OEU22654.1 - 0.13 10.4 11.6 0.05 11.8 6.3 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 BSMAP PF12280.8 OEU22654.1 - 0.17 12.1 2.3 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Brain specific membrane anchored protein CCDC53 PF10152.9 OEU22654.1 - 0.24 11.8 9.7 2.2 8.7 2.9 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AJAP1_PANP_C PF15298.6 OEU22654.1 - 1.6 8.9 12.8 1 9.6 6.8 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Aldose_epim PF01263.20 OEU22656.1 - 2.2e-36 125.7 0.0 2.8e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Tetraspanin PF00335.20 OEU22657.1 - 0.6 9.8 4.2 0.76 9.4 4.2 1.1 1 0 0 1 1 1 0 Tetraspanin family IPPT PF01715.17 OEU22658.1 - 3.6e-43 148.0 0.4 7.9e-30 104.4 0.1 2.3 2 0 0 2 2 2 2 IPP transferase IPT PF01745.16 OEU22658.1 - 3.3e-08 33.2 0.1 8.4e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 OEU22658.1 - 1.9e-05 24.8 0.0 5.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU22658.1 - 0.00039 19.8 0.0 0.01 15.2 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin Cytidylate_kin PF02224.18 OEU22658.1 - 0.072 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase DUF1995 PF09353.10 OEU22659.1 - 1.9e-10 41.1 0.0 3.3e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) CDC45 PF02724.14 OEU22659.1 - 0.0033 15.8 9.4 0.0061 14.9 9.4 1.4 1 0 0 1 1 1 1 CDC45-like protein Macoilin PF09726.9 OEU22659.1 - 0.08 11.5 3.0 0.13 10.8 3.0 1.3 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 OEU22659.1 - 0.087 12.1 11.4 0.16 11.3 11.4 1.4 1 0 0 1 1 1 0 BUD22 SR-25 PF10500.9 OEU22659.1 - 0.13 11.8 8.0 0.31 10.6 8.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_pol_phi PF04931.13 OEU22659.1 - 3.1 5.8 13.0 4.8 5.2 13.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cmc1 PF08583.10 OEU22661.1 - 0.00044 20.2 1.3 0.89 9.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 OEU22661.1 - 0.012 15.9 0.8 0.032 14.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) RPA_interact_N PF14766.6 OEU22661.1 - 0.027 14.1 4.1 0.056 13.1 4.1 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal APS_kinase PF01583.20 OEU22662.1 - 1.4e-57 194.0 0.0 2.3e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 OEU22662.1 - 8.4e-47 159.4 0.0 1.5e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 OEU22662.1 - 2.3e-40 138.0 0.0 3.7e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 OEU22662.1 - 1.4e-33 115.8 0.0 6.3e-33 113.7 0.0 2.2 2 0 0 2 2 2 1 PUA-like domain AAA_33 PF13671.6 OEU22662.1 - 0.0012 19.1 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OEU22662.1 - 0.0015 19.1 0.1 0.0056 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OEU22662.1 - 0.0044 16.3 0.0 0.0093 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 OEU22662.1 - 0.061 13.4 0.1 0.094 12.8 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 OEU22662.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OEU22662.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OEU22662.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OEU22662.1 - 0.13 12.6 0.2 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OEU22662.1 - 0.13 12.7 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 OEU22662.1 - 0.15 11.7 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 OEU22662.1 - 0.21 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_28 PF13521.6 OEU22662.1 - 0.25 11.6 0.6 0.66 10.2 0.4 1.7 1 1 0 1 1 1 0 AAA domain Dus PF01207.17 OEU22663.1 - 1.5e-34 119.5 0.0 3.3e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) VWA_N2 PF16164.5 OEU22663.1 - 0.081 13.1 1.1 0.22 11.7 1.1 1.6 1 0 0 1 1 1 0 VWA N-terminal ACI44 PF15270.6 OEU22663.1 - 0.12 12.6 0.5 0.49 10.6 0.2 2.1 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor TPR_2 PF07719.17 OEU22664.1 - 0.084 13.0 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.9 OEU22664.1 - 2 8.0 15.7 3.6 7.1 15.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 OEU22665.1 - 4.1e-08 32.8 0.1 0.078 13.3 0.1 4.9 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 OEU22665.1 - 0.033 14.6 0.0 0.97 9.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats zf-CW PF07496.15 OEU22666.1 - 1.7e-26 92.0 24.0 1.5e-15 56.9 8.6 2.5 2 0 0 2 2 2 2 CW-type Zinc Finger adh_short PF00106.25 OEU22667.1 - 5.3e-34 117.4 0.1 7.1e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU22667.1 - 5e-22 78.6 0.1 7.9e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU22667.1 - 1.1e-15 58.0 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU22667.1 - 1.6e-05 24.2 0.2 2.1e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OEU22667.1 - 1.8e-05 25.0 0.2 3.3e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 OEU22667.1 - 0.0034 17.3 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 OEU22667.1 - 0.093 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3439 PF11921.8 OEU22667.1 - 0.39 10.7 10.7 2.9 7.9 8.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) AAA PF00004.29 OEU22668.1 - 6.5e-36 123.7 0.3 7.4e-19 68.5 0.1 2.2 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OEU22668.1 - 1.1e-11 44.3 0.0 3.7e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 OEU22668.1 - 3.6e-06 27.3 0.2 1.5e-05 25.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU22668.1 - 9.5e-06 25.7 0.1 0.081 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OEU22668.1 - 4.2e-05 24.0 0.3 0.00017 22.0 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 OEU22668.1 - 0.00079 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 OEU22668.1 - 0.0018 18.1 0.1 0.0089 15.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OEU22668.1 - 0.0027 17.6 0.1 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 OEU22668.1 - 0.0044 16.8 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OEU22668.1 - 0.013 15.7 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OEU22668.1 - 0.013 15.6 0.0 0.039 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 OEU22668.1 - 0.019 14.2 0.1 0.031 13.5 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 OEU22668.1 - 0.021 14.5 0.1 0.14 11.8 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 OEU22668.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 OEU22668.1 - 0.047 13.1 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OEU22668.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 OEU22668.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OEU22668.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OEU22668.1 - 0.082 13.5 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 OEU22668.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_7 PF12775.7 OEU22668.1 - 0.15 11.6 0.1 1.2 8.7 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 OEU22670.1 - 2e-38 131.8 0.0 2.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 OEU22670.1 - 1.8e-07 31.5 0.0 2.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OEU22670.1 - 3.8e-07 30.2 0.0 1.9e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OEU22670.1 - 3.2e-06 27.7 0.0 5.3e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU22670.1 - 5.3e-06 26.9 0.1 2.2e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OEU22670.1 - 9.8e-06 25.9 0.2 0.0003 21.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 OEU22670.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 OEU22670.1 - 0.00029 20.3 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OEU22670.1 - 0.00031 21.3 0.0 0.00043 20.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 OEU22670.1 - 0.00048 20.3 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OEU22670.1 - 0.00079 19.7 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OEU22670.1 - 0.0023 17.7 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OEU22670.1 - 0.005 16.8 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OEU22670.1 - 0.0064 16.4 0.1 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OEU22670.1 - 0.0086 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 OEU22670.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 OEU22670.1 - 0.015 14.9 1.0 0.9 9.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_3 PF07726.11 OEU22670.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OEU22670.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 OEU22670.1 - 0.05 13.3 0.1 0.18 11.5 0.0 1.9 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 OEU22670.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OEU22670.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OEU22670.1 - 0.097 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 OEU22670.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 OEU22670.1 - 0.17 11.6 0.0 0.21 11.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OEU22670.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OEU22670.1 - 0.22 11.4 0.1 4 7.3 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Redoxin PF08534.10 OEU22671.1 - 2.4e-14 53.3 0.0 4.4e-14 52.4 0.0 1.4 1 1 0 1 1 1 1 Redoxin SET PF00856.28 OEU22672.1 - 2.1e-09 38.0 0.0 4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-DBF PF07535.12 OEU22672.1 - 0.17 12.0 2.4 0.5 10.5 2.4 1.8 1 0 0 1 1 1 0 DBF zinc finger PPR_2 PF13041.6 OEU22673.1 - 1.8e-25 88.9 6.6 5.6e-06 26.4 0.0 8.8 5 3 2 7 7 7 7 PPR repeat family PPR_3 PF13812.6 OEU22673.1 - 1.6e-24 85.7 9.1 1.7e-09 37.6 0.9 8.4 5 3 4 9 9 9 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 OEU22673.1 - 1.1e-08 34.6 34.6 0.035 13.8 0.5 11.0 12 1 0 12 12 12 5 PPR repeat PPR_long PF17177.4 OEU22673.1 - 2.9e-08 33.4 0.4 0.013 14.9 0.1 4.8 2 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OEU22673.1 - 0.016 15.4 41.6 0.13 12.5 0.4 11.8 11 5 0 11 11 11 0 PPR repeat AhpC-TSA PF00578.21 OEU22675.1 - 0.0022 17.9 0.0 0.01 15.7 0.0 2.0 2 1 0 2 2 2 1 AhpC/TSA family Phage_TTP_13 PF16463.5 OEU22675.1 - 0.13 11.7 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Phage tail tube protein family Cyclin_N PF00134.23 OEU22676.1 - 3.5e-15 55.9 0.0 6.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OEU22676.1 - 1e-06 28.8 0.8 2.1e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Kelch_1 PF01344.25 OEU22677.1 - 1.1e-29 101.7 4.1 3.8e-08 32.8 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 OEU22677.1 - 9.4e-27 92.8 9.2 5.3e-07 29.5 0.3 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OEU22677.1 - 6.5e-26 89.8 0.3 9.4e-07 28.7 0.1 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OEU22677.1 - 1.1e-24 85.9 7.3 0.00024 21.3 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 OEU22677.1 - 4.7e-24 84.1 21.3 3.9e-06 27.0 0.1 8.2 8 0 0 8 8 8 5 Galactose oxidase, central domain BTB PF00651.31 OEU22677.1 - 7.3e-24 84.1 7.2 4.2e-23 81.7 0.3 3.5 2 1 1 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.15 OEU22677.1 - 5.9e-20 70.4 7.1 0.00066 19.5 0.1 5.9 5 0 0 5 5 5 4 Kelch motif SUIM_assoc PF16619.5 OEU22677.1 - 4.7 7.4 12.5 0.12 12.5 0.3 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Mito_carr PF00153.27 OEU22678.1 - 3.9e-38 129.3 4.6 5.1e-13 48.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.19 OEU22679.1 - 0.0044 17.0 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Tub PF01167.18 OEU22680.1 - 1.2e-48 166.0 0.0 2.5e-48 165.0 0.0 1.5 1 1 0 1 1 1 1 Tub family YhdB PF14148.6 OEU22681.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 YhdB-like protein DUF2439 PF10382.9 OEU22682.1 - 3e-08 33.9 0.0 1.9e-07 31.3 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2439) zf-C3HC4_3 PF13920.6 OEU22683.1 - 1.1e-08 34.8 4.5 1.6e-08 34.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU22683.1 - 3.9e-05 23.5 5.7 6.6e-05 22.8 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OEU22683.1 - 0.0016 18.5 4.4 0.0034 17.4 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OEU22683.1 - 0.005 16.6 0.2 0.012 15.3 0.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger WD40 PF00400.32 OEU22684.1 - 1.7e-16 60.3 21.3 0.02 15.8 0.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22684.1 - 2.4e-07 30.9 0.7 0.12 12.7 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU22684.1 - 0.00035 19.7 0.6 0.26 10.2 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4245 PF14030.6 OEU22684.1 - 0.085 12.9 1.0 0.63 10.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Myb_DNA-binding PF00249.31 OEU22685.1 - 3.5e-32 110.3 6.8 8.3e-17 61.1 1.3 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU22685.1 - 2e-26 92.0 7.4 1.7e-15 57.0 1.1 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OEU22685.1 - 5.7e-07 29.5 0.1 0.023 14.7 0.1 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OEU22685.1 - 0.00078 19.3 1.4 0.012 15.5 0.2 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OEU22685.1 - 0.011 15.9 0.3 0.77 10.0 0.1 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OEU22685.1 - 0.012 15.8 1.0 0.12 12.6 0.2 2.5 1 1 1 2 2 2 0 Rap1 Myb domain HTH_AsnC-type PF13404.6 OEU22685.1 - 0.015 15.1 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 OEU22685.1 - 0.056 13.1 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-bind_4 PF13837.6 OEU22685.1 - 0.064 13.6 7.8 0.23 11.9 2.3 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Med26 PF08711.11 OEU22686.1 - 0.0028 17.7 0.7 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Elongin_A PF06881.11 OEU22686.1 - 0.0048 17.4 0.6 0.059 13.9 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1190 PF06693.11 OEU22686.1 - 0.39 11.1 3.5 0.31 11.4 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1190) DEAD PF00270.29 OEU22687.1 - 5.6e-49 166.3 0.0 8e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OEU22687.1 - 9.7e-30 103.2 0.0 2.1e-28 98.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OEU22687.1 - 9.2e-07 29.0 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIA PF03153.13 OEU22688.1 - 2.6 8.0 16.6 1.4 8.8 7.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit A_deamin PF02137.18 OEU22690.1 - 3.8e-43 148.2 3.2 9e-30 104.2 0.1 3.0 1 1 0 2 2 2 2 Adenosine-deaminase (editase) domain Tnp_22_trimer PF17489.2 OEU22690.1 - 0.67 10.0 3.5 1.3 9.0 1.4 2.4 2 0 0 2 2 2 0 L1 transposable element trimerization domain TFIIA PF03153.13 OEU22691.1 - 0.084 12.9 16.4 0.11 12.5 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RPA_C PF08784.11 OEU22691.1 - 0.11 13.1 6.2 0.37 11.5 5.5 2.2 1 1 0 1 1 1 0 Replication protein A C terminal Sec62 PF03839.16 OEU22691.1 - 0.63 9.5 7.2 1.1 8.7 7.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PCI PF01399.27 OEU22692.1 - 4.7e-12 46.4 0.0 8.3e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain SIR2 PF02146.17 OEU22693.1 - 2.9e-25 89.2 0.5 1.1e-16 61.3 0.0 2.2 2 0 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 OEU22693.1 - 0.0018 18.1 0.1 0.65 9.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Presenilin PF01080.17 OEU22693.1 - 0.019 13.8 5.6 0.024 13.4 5.6 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OEU22693.1 - 0.021 13.7 10.6 0.028 13.3 10.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 OEU22693.1 - 0.062 10.4 6.1 0.07 10.3 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 OEU22693.1 - 0.078 11.5 9.7 0.1 11.2 9.7 1.1 1 0 0 1 1 1 0 Macoilin family Mem_trans PF03547.18 OEU22693.1 - 0.13 10.6 0.1 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein NPR3 PF03666.13 OEU22693.1 - 0.14 10.9 11.8 0.19 10.4 11.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 OEU22693.1 - 0.15 10.4 4.9 0.19 10.1 4.9 1.1 1 0 0 1 1 1 0 Menin PAP1 PF08601.10 OEU22693.1 - 0.15 11.8 14.0 0.22 11.2 14.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ndc1_Nup PF09531.10 OEU22693.1 - 0.26 9.9 6.1 0.31 9.7 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIIAH PF12685.7 OEU22693.1 - 0.47 10.2 8.3 0.71 9.7 8.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein MAP70 PF07058.11 OEU22693.1 - 0.5 9.0 7.7 0.67 8.6 7.7 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Lin-8 PF03353.15 OEU22693.1 - 0.51 9.9 7.6 0.72 9.4 7.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CSRNP_N PF16019.5 OEU22693.1 - 0.75 9.7 10.6 1.2 8.9 10.6 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Apc15p PF05841.11 OEU22693.1 - 1 10.2 12.4 1.6 9.5 12.4 1.3 1 0 0 1 1 1 0 Apc15p protein Hid1 PF12722.7 OEU22693.1 - 1.3 7.1 7.9 1.6 6.8 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM199X PF15814.5 OEU22693.1 - 1.5 7.8 12.9 0.46 9.5 10.0 1.5 2 0 0 2 2 2 0 Protein family FAM199X SR-25 PF10500.9 OEU22693.1 - 1.6 8.3 27.4 2.8 7.5 27.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MCM_bind PF09739.9 OEU22693.1 - 2.7 6.3 12.4 3.8 5.8 12.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 OEU22693.1 - 3.9 6.4 10.6 1.4 7.8 6.5 1.9 2 0 0 2 2 2 0 Solute carrier family 12 Zip PF02535.22 OEU22693.1 - 4.1 6.5 4.9 5.5 6.1 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cut8 PF08559.10 OEU22693.1 - 5.2 6.6 12.9 0.8 9.3 9.1 1.5 1 1 1 2 2 2 0 Cut8, nuclear proteasome tether protein CCDC106 PF15794.5 OEU22693.1 - 5.7 6.6 17.5 8.9 6.0 17.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4692 PF15763.5 OEU22693.1 - 6.2 7.3 14.3 10 6.6 14.3 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) PCIF1_WW PF12237.8 OEU22694.1 - 1.8e-37 128.6 3.3 4.8e-36 124.0 3.3 2.5 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain MFS_1 PF07690.16 OEU22696.1 - 3.5e-24 85.4 35.0 1.9e-22 79.7 17.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 OEU22696.1 - 0.0065 15.2 0.7 0.026 13.3 0.1 2.0 2 1 0 2 2 2 1 Reduced folate carrier DUF4131 PF13567.6 OEU22696.1 - 0.072 12.7 0.0 0.072 12.7 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) OATP PF03137.20 OEU22696.1 - 4.5 5.4 10.4 0.98 7.6 0.1 3.1 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TCR_zetazeta PF11628.8 OEU22696.1 - 5.1 6.8 13.2 1 9.1 3.7 2.7 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Corona_S2 PF01601.16 OEU22697.1 - 0.029 12.9 0.8 0.042 12.3 0.8 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TMEM52 PF14979.6 OEU22697.1 - 0.48 10.3 5.2 0.47 10.4 2.7 2.1 2 0 0 2 2 2 0 Transmembrane 52 tRNA-synt_2 PF00152.20 OEU22698.1 - 1.4e-74 251.0 0.0 1.9e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OEU22698.1 - 7.8e-10 38.6 0.8 2.8e-09 36.8 0.2 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OEU22698.1 - 6e-05 22.6 0.2 0.027 14.0 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 OEU22698.1 - 0.078 12.9 0.0 0.37 10.8 0.0 2.1 2 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Kelch_4 PF13418.6 OEU22699.1 - 1.9e-28 98.2 0.1 6.2e-08 32.5 0.0 6.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OEU22699.1 - 7e-28 96.3 0.0 4.9e-08 33.1 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OEU22699.1 - 2.4e-23 81.4 3.4 2e-05 24.1 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 OEU22699.1 - 1.7e-22 79.0 0.0 0.0013 18.7 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OEU22699.1 - 3.5e-22 77.9 0.2 2.2e-05 24.5 0.0 6.2 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 OEU22699.1 - 9.3e-21 73.7 0.1 9.3e-21 73.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 OEU22699.1 - 4e-12 45.6 20.6 0.04 13.9 0.1 7.5 7 2 0 7 7 7 4 Kelch motif RCC1 PF00415.18 OEU22700.1 - 1.7e-55 185.4 14.8 2.4e-11 44.1 0.0 6.2 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU22700.1 - 1.3e-23 82.2 42.4 4e-06 26.5 0.3 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PPR PF01535.20 OEU22701.1 - 9.1e-12 44.4 2.6 0.001 19.2 0.1 7.3 9 0 0 9 9 9 3 PPR repeat PPR_1 PF12854.7 OEU22701.1 - 4e-09 36.0 0.0 0.00014 21.5 0.0 5.2 5 0 0 5 5 5 1 PPR repeat PPR_2 PF13041.6 OEU22701.1 - 1.4e-08 34.8 0.0 0.031 14.5 0.0 7.1 7 2 0 7 7 7 2 PPR repeat family PPR_long PF17177.4 OEU22701.1 - 0.0019 17.6 0.3 1.1 8.5 0.0 3.1 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 OEU22701.1 - 0.0046 17.0 0.0 2.1 8.5 0.0 4.1 4 2 0 4 4 4 1 Pentatricopeptide repeat domain Wzy_C_2 PF11846.8 OEU22701.1 - 0.025 14.5 0.2 0.26 11.2 0.2 2.5 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal I-set PF07679.16 OEU22701.1 - 0.13 12.3 0.3 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain W2 PF02020.18 OEU22701.1 - 0.19 11.9 1.5 7 6.9 0.0 4.0 4 1 0 4 4 4 0 eIF4-gamma/eIF5/eIF2-epsilon TetR_C_8 PF14278.6 OEU22701.1 - 0.45 10.7 2.9 23 5.1 0.0 4.4 6 0 0 6 6 6 0 Transcriptional regulator C-terminal region DNA_pol_B PF00136.21 OEU22702.1 - 3.8e-74 250.1 0.0 5.4e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OEU22702.1 - 0.0026 17.0 0.0 0.0053 15.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OEU22702.1 - 0.021 15.3 12.4 0.056 13.9 12.4 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta NACHT PF05729.12 OEU22702.1 - 0.025 14.5 0.0 0.089 12.7 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Homeobox_KN PF05920.11 OEU22704.1 - 1.8e-15 56.6 0.1 2.7e-15 56.0 0.2 1.3 1 1 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OEU22704.1 - 1.1e-06 28.4 0.2 1.3e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 Homeodomain zf-RanBP PF00641.18 OEU22706.1 - 0.00029 20.1 1.8 0.00029 20.1 1.8 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF456 PF04306.13 OEU22706.1 - 0.005 17.1 0.1 0.007 16.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF3040 PF11239.8 OEU22706.1 - 0.051 13.8 0.2 0.096 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PHD_2 PF13831.6 OEU22706.1 - 4.7 6.9 6.0 0.3 10.7 0.8 1.8 2 0 0 2 2 2 0 PHD-finger Cupin_4 PF08007.12 OEU22707.1 - 4.4e-15 56.0 0.1 2.4e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 OEU22707.1 - 0.0021 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Ion_trans PF00520.31 OEU22708.1 - 6.9e-10 38.6 2.5 9.4e-10 38.1 2.5 1.1 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 OEU22708.1 - 1.8e-05 24.0 0.0 3.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OEU22708.1 - 0.00014 21.2 0.1 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OEU22708.1 - 0.00027 21.3 0.4 0.0007 20.0 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU22708.1 - 0.0079 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 OEU22708.1 - 0.048 13.5 0.4 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 EF-hand domain pair MIX PF18529.1 OEU22708.1 - 0.13 12.0 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins MIF4G PF02854.19 OEU22709.1 - 8e-33 113.9 0.5 7.7e-15 55.1 0.0 4.7 4 0 0 4 4 4 4 MIF4G domain Upf2 PF04050.14 OEU22709.1 - 8.1e-15 55.8 4.9 8.1e-15 55.8 4.9 4.2 3 1 1 4 4 4 1 Up-frameshift suppressor 2 BAGE PF08180.11 OEU22709.1 - 0.059 13.5 0.3 0.16 12.1 0.3 1.7 1 0 0 1 1 1 0 B melanoma antigen family ECH_1 PF00378.20 OEU22710.1 - 2.7e-37 128.4 0.0 9.8e-21 74.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OEU22710.1 - 2.6e-32 112.7 0.0 3.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RNA_pol_Rpc34 PF05158.12 OEU22710.1 - 0.068 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit RIO1 PF01163.22 OEU22711.1 - 1.6e-68 230.0 3.3 1.9e-68 229.8 0.2 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OEU22711.1 - 4.2e-05 23.6 0.1 0.00053 20.0 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family TFIIB PF00382.19 OEU22712.1 - 3e-33 113.7 0.6 4.8e-17 61.8 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OEU22712.1 - 1.4e-16 60.7 5.4 2.2e-16 60.0 5.4 1.3 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 OEU22712.1 - 1.9e-11 43.2 1.0 3.6e-11 42.4 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OEU22712.1 - 0.0012 18.6 0.2 1.3 8.7 0.0 2.6 2 1 0 2 2 2 2 Cyclin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 OEU22712.1 - 0.026 14.5 0.5 0.064 13.2 0.5 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OEU22712.1 - 0.04 13.9 0.6 0.094 12.7 0.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 OEU22712.1 - 0.047 13.4 2.1 3.9 7.3 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 OEU22712.1 - 0.11 12.5 0.3 0.27 11.3 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon RE_HindIII PF09518.10 OEU22712.1 - 0.3 10.3 2.4 0.46 9.7 2.4 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease zf-ribbon_3 PF13248.6 OEU22712.1 - 0.53 9.8 7.7 1.1 8.8 5.5 2.4 2 1 1 3 3 3 0 zinc-ribbon domain zf-RRN7 PF11781.8 OEU22712.1 - 2.3 7.9 5.2 15 5.3 5.2 2.2 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 IF-2B PF01008.17 OEU22713.1 - 4.2e-65 219.8 0.1 4.8e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family IFT46_B_C PF12317.8 OEU22713.1 - 0.0075 16.0 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Spectrin PF00435.21 OEU22713.1 - 0.026 15.0 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Spectrin repeat DUF1307 PF06998.11 OEU22713.1 - 0.078 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) VWA_2 PF13519.6 OEU22713.1 - 0.079 13.6 0.1 3.9 8.2 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain zf-CCCH PF00642.24 OEU22715.1 - 1.5e-05 24.7 8.4 0.0003 20.6 1.5 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU22715.1 - 5.4e-05 23.1 4.7 5.4e-05 23.1 4.7 2.2 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 OEU22715.1 - 0.0043 17.7 18.4 0.013 16.2 4.5 3.1 1 1 2 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 OEU22715.1 - 0.14 12.7 8.8 0.092 13.3 2.0 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TAF4 PF05236.14 OEU22715.1 - 0.32 10.7 10.9 0.014 15.2 5.2 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family zf-CCCH_3 PF15663.5 OEU22715.1 - 0.72 10.1 9.1 0.43 10.8 2.4 2.7 1 1 1 2 2 2 0 Zinc-finger containing family Top6b_C PF18000.1 OEU22716.1 - 0.057 13.6 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Helicase_C PF00271.31 OEU22717.1 - 6.9e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 OEU22717.1 - 8.7e-06 26.0 6.5 1.5e-05 25.2 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OEU22717.1 - 0.00041 20.1 6.7 0.00095 19.0 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU22717.1 - 0.0035 17.2 5.1 0.0063 16.4 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU22717.1 - 0.0054 16.7 4.3 0.011 15.8 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU22717.1 - 0.0089 16.0 6.2 0.015 15.2 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OEU22717.1 - 0.0097 15.7 4.7 0.018 14.9 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OEU22717.1 - 0.037 13.8 5.5 0.085 12.6 5.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 OEU22717.1 - 0.063 13.6 3.6 0.15 12.4 3.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Pox_TAP PF03355.14 OEU22717.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral Trans-Activator Protein SRP54_N PF02881.19 OEU22717.1 - 0.093 13.0 0.3 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain zf-Nse PF11789.8 OEU22717.1 - 0.38 10.6 2.0 0.83 9.5 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OEU22717.1 - 0.48 10.6 3.9 0.93 9.7 3.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LicD PF04991.13 OEU22718.1 - 0.0078 16.4 0.2 0.036 14.2 0.0 1.9 2 0 0 2 2 2 1 LicD family DUF2600 PF10776.9 OEU22718.1 - 0.082 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) DUF3460 PF11943.8 OEU22718.1 - 0.68 10.2 2.5 30 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Fis1_TPR_N PF14852.6 OEU22719.1 - 0.46 10.2 1.4 0.92 9.2 1.4 1.4 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat FSH1 PF03959.13 OEU22720.1 - 0.04 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) 2OG-FeII_Oxy_3 PF13640.6 OEU22721.1 - 2.9e-10 40.9 0.2 3.1e-06 28.0 0.0 3.0 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU22721.1 - 4.9e-07 30.3 0.0 0.00042 20.9 0.0 3.0 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily LRR_8 PF13855.6 OEU22722.1 - 0.0076 16.0 1.1 0.015 15.0 1.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LST1 PF05083.13 OEU22722.1 - 0.0094 16.2 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 1 LST-1 protein DUF1462 PF07315.11 OEU22723.1 - 0.013 15.7 0.1 0.031 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Podoplanin PF05808.11 OEU22723.1 - 0.1 12.7 2.2 0.2 11.7 1.0 1.8 2 0 0 2 2 2 0 Podoplanin Stevor PF17410.2 OEU22723.1 - 0.19 11.2 4.2 0.35 10.4 4.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Nipped-B_C PF12830.7 OEU22724.1 - 5e-32 111.4 1.4 1.6e-31 109.8 0.1 2.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OEU22724.1 - 2.9e-14 53.0 2.0 1.2e-11 44.6 0.6 2.9 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion PHD PF00628.29 OEU22724.1 - 1e-08 34.9 8.1 3.1e-08 33.4 8.1 1.9 1 0 0 1 1 1 1 PHD-finger HEAT_2 PF13646.6 OEU22724.1 - 2.6e-08 34.2 0.5 0.12 12.8 0.0 3.7 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 OEU22724.1 - 1e-07 31.6 0.3 2 8.9 0.0 5.5 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 OEU22724.1 - 1.6e-07 31.6 0.1 0.0015 18.6 0.0 3.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OEU22724.1 - 3.7e-06 25.8 0.2 0.034 12.7 0.0 4.1 3 1 1 4 4 4 2 Adaptin N terminal region PHD_2 PF13831.6 OEU22724.1 - 0.00012 21.5 2.8 0.00012 21.5 2.8 2.7 3 0 0 3 3 3 1 PHD-finger HEAT_EZ PF13513.6 OEU22724.1 - 0.00021 21.7 0.1 2.9 8.5 0.0 3.9 3 0 0 3 3 3 2 HEAT-like repeat PHD_3 PF13922.6 OEU22724.1 - 0.0026 18.1 1.1 0.02 15.3 1.0 2.6 2 0 0 2 2 2 1 PHD domain of transcriptional enhancer, Asx Cnd3 PF12719.7 OEU22724.1 - 0.0034 16.6 0.0 0.079 12.1 0.0 2.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain PHD_4 PF16866.5 OEU22724.1 - 3.8 7.7 5.2 15 5.8 5.2 2.1 1 0 0 1 1 1 0 PHD-finger SecY PF00344.20 OEU22725.1 - 8.6e-71 238.7 12.4 1.1e-70 238.4 12.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OEU22725.1 - 2.1e-18 65.9 0.1 2.1e-18 65.9 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p Pro-MCH PF05824.12 OEU22727.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) RibD_C PF01872.17 OEU22727.1 - 0.085 12.7 1.5 0.093 12.5 0.3 1.7 2 0 0 2 2 2 0 RibD C-terminal domain Syntaxin-6_N PF09177.11 OEU22727.1 - 0.099 13.2 1.7 0.3 11.7 1.7 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF1635 PF07795.11 OEU22727.1 - 0.33 10.8 7.7 0.67 9.8 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MAP17 PF15807.5 OEU22727.1 - 1 9.6 3.9 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ly49 PF08391.10 OEU22727.1 - 2.6 8.4 6.6 2.4 8.5 3.8 2.3 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region RusA PF05866.11 OEU22728.1 - 1.4e-06 28.8 0.0 2.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA WD40 PF00400.32 OEU22730.1 - 2.9e-12 46.9 10.3 2.8e-05 24.8 0.1 6.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ank_2 PF12796.7 OEU22730.1 - 3.8e-12 46.6 0.4 2.9e-08 34.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) ANAPC4_WD40 PF12894.7 OEU22730.1 - 2.7e-07 30.8 0.0 0.042 14.1 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ank_5 PF13857.6 OEU22730.1 - 1.4e-06 28.5 0.1 8.5e-06 26.0 0.1 2.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22730.1 - 1.8e-06 27.9 0.3 0.00051 20.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OEU22730.1 - 0.00012 22.6 0.1 0.0009 19.8 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OEU22730.1 - 0.00085 19.7 0.0 0.089 13.3 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeat Ge1_WD40 PF16529.5 OEU22730.1 - 0.56 9.1 5.3 0.09 11.7 0.7 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPP1-like PF11833.8 OEU22730.1 - 4.2 7.0 4.9 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3348 PF11828.8 OEU22731.1 - 0.0029 17.3 0.5 0.0044 16.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) Ank_2 PF12796.7 OEU22732.1 - 2.5e-05 24.8 0.0 4.4e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OEU22732.1 - 0.0002 21.6 0.0 0.018 15.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU22732.1 - 0.00077 19.7 0.0 3.4 8.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OEU22732.1 - 0.0023 18.5 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU22732.1 - 0.14 12.6 0.1 16 6.2 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeat TPR_2 PF07719.17 OEU22733.1 - 7.5e-18 63.1 15.7 0.00018 21.4 0.2 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OEU22733.1 - 1e-12 47.3 14.2 0.00061 19.5 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat FYVE PF01363.21 OEU22733.1 - 9.4e-08 32.1 1.5 9.4e-08 32.1 1.5 1.8 2 0 0 2 2 1 1 FYVE zinc finger TPR_11 PF13414.6 OEU22733.1 - 1.2e-07 31.3 11.6 0.0061 16.2 0.2 5.0 4 1 1 5 5 5 3 TPR repeat Ank_2 PF12796.7 OEU22733.1 - 1e-06 29.2 0.0 0.0002 21.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TPR_16 PF13432.6 OEU22733.1 - 1.3e-06 28.9 12.9 0.01 16.4 4.7 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_4 PF13637.6 OEU22733.1 - 7.1e-06 26.5 0.0 0.0049 17.4 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Synaptobrevin PF00957.21 OEU22733.1 - 1.2e-05 25.0 2.8 4.3e-05 23.2 2.8 2.0 1 0 0 1 1 1 1 Synaptobrevin TPR_8 PF13181.6 OEU22733.1 - 1.5e-05 24.9 14.2 0.024 14.8 0.1 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat Ank_3 PF13606.6 OEU22733.1 - 0.00096 19.4 0.0 0.0064 16.9 0.0 2.5 2 0 0 2 2 1 1 Ankyrin repeat Ank PF00023.30 OEU22733.1 - 0.0041 17.5 0.0 0.03 14.8 0.0 2.5 2 0 0 2 2 1 1 Ankyrin repeat DUF4428 PF14471.6 OEU22733.1 - 0.0081 16.1 0.7 0.0081 16.1 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4428) TPR_6 PF13174.6 OEU22733.1 - 0.0093 16.6 2.7 0.076 13.7 0.1 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Ank_5 PF13857.6 OEU22733.1 - 0.015 15.6 0.0 0.053 13.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) TPR_17 PF13431.6 OEU22733.1 - 0.12 12.8 0.1 2.4 8.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU22733.1 - 0.18 12.7 13.7 1 10.3 0.0 5.4 4 2 3 7 7 4 0 Tetratricopeptide repeat Zf_RING PF16744.5 OEU22733.1 - 0.69 10.1 4.0 7.5 6.7 2.3 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger TPR_12 PF13424.6 OEU22733.1 - 0.87 9.9 8.1 18 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU22733.1 - 4.3 7.6 5.4 14 5.9 1.8 3.3 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FYVE_2 PF02318.16 OEU22733.1 - 6.2 7.1 8.3 0.13 12.5 0.3 2.3 2 0 0 2 2 1 0 FYVE-type zinc finger TPR_19 PF14559.6 OEU22733.1 - 8.8 6.9 9.5 25 5.5 0.3 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Rubredoxin PF00301.20 OEU22734.1 - 3.7e-17 62.1 1.1 5.4e-17 61.6 1.1 1.3 1 0 0 1 1 1 1 Rubredoxin HypA PF01155.19 OEU22734.1 - 0.042 13.9 0.1 0.056 13.5 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5318 PF17249.2 OEU22734.1 - 0.05 13.4 0.6 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5318) Rubredoxin_2 PF18073.1 OEU22734.1 - 0.16 11.8 5.9 3.2 7.5 0.6 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Cys_rich_CPCC PF14206.6 OEU22734.1 - 0.18 11.6 3.3 1.3 8.9 0.1 2.7 2 1 0 2 2 2 0 Cysteine-rich CPCC SLC35F PF06027.12 OEU22735.1 - 3.3e-44 151.6 19.7 6.2e-44 150.7 19.7 1.4 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OEU22735.1 - 3.5e-12 46.7 26.6 9.7e-09 35.5 9.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 OEU22735.1 - 7.1e-10 38.4 0.4 7.1e-10 38.4 0.4 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 OEU22735.1 - 5.9e-09 35.5 18.4 8.5e-09 35.0 18.4 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 OEU22735.1 - 0.033 13.4 14.1 0.021 14.0 11.9 1.8 1 1 1 2 2 2 0 Nucleotide-sugar transporter Cyclin_N PF00134.23 OEU22736.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OEU22736.1 - 0.0021 18.4 0.1 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain DUF3754 PF12576.8 OEU22737.1 - 7.5e-27 93.9 0.1 1.9e-26 92.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) EBV-NA3 PF05009.12 OEU22737.1 - 0.11 12.1 0.6 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) MtN3_slv PF03083.16 OEU22738.1 - 1.4e-27 95.6 9.7 4.6e-18 65.0 3.0 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Arv1 PF04161.13 OEU22739.1 - 8.5e-25 88.2 8.1 1.9e-24 87.0 8.1 1.6 1 0 0 1 1 1 1 Arv1-like family DUF4386 PF14329.6 OEU22739.1 - 0.0066 16.3 0.1 0.035 14.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) DUF4667 PF15700.5 OEU22739.1 - 0.81 9.7 20.5 2.5 8.1 20.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) DDHD PF02862.17 OEU22739.1 - 0.94 9.6 5.7 3.3 7.8 5.7 1.9 1 1 0 1 1 1 0 DDHD domain DUF3437 PF11919.8 OEU22741.1 - 1.6e-26 92.0 0.7 4.4e-26 90.6 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Shikimate_DH PF01488.20 OEU22741.1 - 0.079 13.0 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CP12 PF02672.15 OEU22741.1 - 0.22 12.3 2.9 0.15 12.9 1.0 1.7 2 0 0 2 2 2 0 CP12 domain DUF2986 PF11661.8 OEU22741.1 - 1.5 9.4 10.5 2 9.0 0.5 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2986) SLC3A2_N PF16028.5 OEU22742.1 - 0.022 14.3 0.6 0.053 13.1 0.6 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF647 PF04884.14 OEU22743.1 - 2e-62 211.0 0.2 2.2e-62 210.9 0.2 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Med4 PF10018.9 OEU22744.1 - 1.5e-06 28.0 9.3 6.3e-06 26.0 9.0 2.0 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Cwf_Cwc_15 PF04889.12 OEU22744.1 - 0.024 14.4 22.0 0.042 13.6 22.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med19 PF10278.9 OEU22744.1 - 0.081 12.9 7.9 0.13 12.2 7.9 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 OSTbeta PF15048.6 OEU22744.1 - 0.17 12.0 3.9 0.33 11.1 3.9 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SID-1_RNA_chan PF13965.6 OEU22744.1 - 0.21 10.0 1.1 0.24 9.7 1.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4228 PF14009.6 OEU22744.1 - 0.33 11.3 9.2 2 8.8 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF3499 PF12005.8 OEU22744.1 - 0.62 10.7 4.1 1.7 9.2 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) PBP_sp32 PF07222.12 OEU22744.1 - 0.83 9.1 7.1 2.1 7.8 7.1 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Hid1 PF12722.7 OEU22744.1 - 2.5 6.1 8.9 2.5 6.1 8.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 OEU22744.1 - 3.9 6.9 9.0 5.8 6.4 9.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 MCM_bind PF09739.9 OEU22744.1 - 3.9 5.8 10.9 6.4 5.1 10.9 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NARP1 PF12569.8 OEU22744.1 - 4.1 6.2 15.2 6.4 5.6 15.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2151 PF10221.9 OEU22744.1 - 4.2 5.8 10.7 5.6 5.4 10.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Paramyxo_ncap PF00973.19 OEU22744.1 - 5 5.9 8.0 6.4 5.6 8.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein XRN_M PF17846.1 OEU22744.1 - 5.6 5.8 9.1 9 5.1 9.1 1.4 1 0 0 1 1 1 0 Xrn1 helical domain MAS20 PF02064.15 OEU22744.1 - 6.1 7.0 10.1 13 5.9 10.1 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor MscS_TM PF12794.7 OEU22744.1 - 7.8 5.2 8.5 13 4.6 8.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Prion PF00377.18 OEU22745.1 - 6.5 6.6 8.3 1.7 8.5 2.6 2.4 1 1 1 2 2 2 0 Prion/Doppel alpha-helical domain SKICH PF17751.1 OEU22746.1 - 0.00018 22.0 1.4 0.00041 20.9 1.4 1.6 1 1 0 1 1 1 1 SKICH domain fn3_PAP PF17808.1 OEU22746.1 - 0.021 14.9 0.2 0.031 14.4 0.2 1.4 1 1 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase HECW_N PF16562.5 OEU22746.1 - 0.052 13.4 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_Zc3h12a PF11977.8 OEU22747.1 - 3.1e-10 40.0 0.0 2.4e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain NFACT-R_1 PF05670.13 OEU22748.1 - 2.1e-10 41.2 0.0 3.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 OEU22748.1 - 0.0011 19.1 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain Laminin_II PF06009.12 OEU22748.1 - 0.053 13.5 0.8 0.053 13.5 0.8 1.9 2 1 1 3 3 3 0 Laminin Domain II I_LWEQ PF01608.17 OEU22748.1 - 0.082 13.2 1.2 0.16 12.2 1.2 1.5 1 0 0 1 1 1 0 I/LWEQ domain NPV_P10 PF05531.12 OEU22748.1 - 0.31 11.5 4.9 2 8.9 1.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 OEU22748.1 - 0.87 9.7 5.0 2.6 8.2 3.3 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2730 PF10805.8 OEU22748.1 - 1.1 9.4 5.8 0.42 10.7 0.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DnaJ PF00226.31 OEU22749.1 - 7.3e-16 58.1 2.1 2.2e-15 56.5 2.1 1.9 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 OEU22749.1 - 1.3e-12 47.6 1.4 8.7e-12 44.9 0.3 2.6 2 1 0 2 2 2 1 X-domain of DnaJ-containing MDM10 PF12519.8 OEU22749.1 - 0.47 9.3 8.6 0.69 8.7 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 FAM60A PF15396.6 OEU22749.1 - 2.1 8.3 10.4 7.7 6.5 7.2 2.8 2 1 0 2 2 2 0 Protein Family FAM60A Mito_carr PF00153.27 OEU22751.1 - 1.4e-39 133.9 1.4 1.3e-14 53.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Form_Nir_trans PF01226.17 OEU22751.1 - 0.017 14.5 0.1 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 Formate/nitrite transporter RNB PF00773.19 OEU22755.1 - 3.6e-89 299.3 0.0 4.8e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OEU22755.1 - 7.9e-16 57.9 0.0 1.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OEU22755.1 - 9.5e-06 25.4 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 OEU22755.1 - 0.011 15.8 0.0 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 Cold shock domain SurA_N_2 PF13623.6 OEU22755.1 - 0.085 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain GTP_EFTU PF00009.27 OEU22757.1 - 1.1e-34 119.7 0.0 2.2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OEU22757.1 - 5.1e-19 68.4 0.0 1.5e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 OEU22757.1 - 4.1e-17 61.8 0.3 1.6e-16 60.0 0.3 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 OEU22757.1 - 8.2e-10 38.9 10.7 1.1e-06 29.0 0.2 4.0 4 1 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OEU22757.1 - 2.4e-08 34.1 0.6 8e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OEU22757.1 - 4.7e-05 23.6 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OEU22757.1 - 0.00012 21.6 0.8 0.15 11.5 0.3 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OEU22757.1 - 0.0018 18.2 1.4 0.42 10.5 0.3 2.7 1 1 1 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OEU22757.1 - 0.0026 18.0 0.1 0.0072 16.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 OEU22757.1 - 0.0028 17.2 0.1 0.02 14.4 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Ras PF00071.22 OEU22757.1 - 0.0062 16.2 0.0 0.035 13.7 0.0 2.3 1 1 0 1 1 1 1 Ras family TniB PF05621.11 OEU22757.1 - 0.015 14.7 0.1 0.042 13.3 0.1 1.8 1 1 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 OEU22757.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 OEU22757.1 - 0.18 11.4 1.1 1.3 8.6 0.6 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PAP_fibrillin PF04755.12 OEU22758.1 - 2.6e-18 66.7 0.2 2.8e-11 43.7 0.1 2.3 2 1 0 2 2 2 2 PAP_fibrillin DUF2153 PF09921.9 OEU22759.1 - 0.0028 17.4 2.7 0.049 13.4 1.1 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2153) ApoLp-III PF07464.11 OEU22759.1 - 0.003 17.7 0.9 0.0079 16.3 0.3 2.0 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Metal_resist PF13801.6 OEU22759.1 - 0.013 15.7 3.4 0.4 10.9 0.0 3.3 1 1 1 3 3 3 0 Heavy-metal resistance SNAP PF14938.6 OEU22759.1 - 0.022 14.2 0.4 0.032 13.7 0.4 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Seryl_tRNA_N PF02403.22 OEU22759.1 - 0.024 14.8 0.4 16 5.8 0.0 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain eIF3_N PF09440.10 OEU22759.1 - 0.18 12.2 4.9 2.5 8.6 0.2 2.8 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain Bep_C_terminal PF17841.1 OEU22759.1 - 0.28 11.4 2.6 0.89 9.8 0.4 2.9 2 1 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Spectrin PF00435.21 OEU22759.1 - 3.2 8.3 7.5 2.5 8.6 2.1 3.1 3 2 0 3 3 3 0 Spectrin repeat Methyltransf_25 PF13649.6 OEU22760.1 - 1.4e-07 32.2 0.0 0.0015 19.2 0.0 3.1 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 OEU22760.1 - 3.1e-05 23.8 0.0 0.00037 20.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU22760.1 - 9.7e-05 22.9 0.0 0.027 15.1 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU22760.1 - 0.00012 21.9 0.0 0.00046 20.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU22760.1 - 0.0095 16.7 0.1 0.072 13.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 OEU22760.1 - 0.01 15.0 0.0 1.2 8.2 0.0 2.8 3 0 0 3 3 3 1 Putative methyltransferase Shisa PF13908.6 OEU22760.1 - 0.067 13.4 0.3 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SIR2 PF02146.17 OEU22760.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Sir2 family Rsm22 PF09243.10 OEU22760.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Bin3 PF06859.12 OEU22760.1 - 0.14 12.8 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) DUF705 PF05152.12 OEU22761.1 - 0.037 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF705) AAA PF00004.29 OEU22763.1 - 6.7e-66 220.7 0.0 9.4e-41 139.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU22763.1 - 2e-13 51.1 1.2 2.4e-06 28.1 0.3 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 OEU22763.1 - 3.9e-13 49.0 1.2 2.6e-06 27.1 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 OEU22763.1 - 3.5e-10 40.0 0.0 0.0014 18.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OEU22763.1 - 2e-08 34.1 0.0 8.4e-05 22.4 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OEU22763.1 - 6.2e-08 32.9 0.0 0.0042 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OEU22763.1 - 2.2e-06 28.0 0.5 0.013 15.7 0.1 3.8 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OEU22763.1 - 7.8e-06 25.7 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 OEU22763.1 - 2.2e-05 24.0 0.0 0.0089 15.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OEU22763.1 - 2.8e-05 24.4 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 OEU22763.1 - 6.9e-05 22.9 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OEU22763.1 - 0.00054 19.3 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 OEU22763.1 - 0.002 18.3 0.0 2.9 8.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OEU22763.1 - 0.0029 17.2 0.0 2.8 7.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 OEU22763.1 - 0.0031 17.5 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Hpr_kinase_C PF07475.12 OEU22763.1 - 0.0035 16.9 0.0 0.07 12.6 0.0 2.3 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain NACHT PF05729.12 OEU22763.1 - 0.0036 17.2 0.3 1.1 9.1 0.1 3.5 3 1 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 OEU22763.1 - 0.0044 16.4 0.1 0.5 9.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OEU22763.1 - 0.006 16.3 0.0 1.4 8.6 0.0 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 OEU22763.1 - 0.0065 16.2 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 OEU22763.1 - 0.0075 15.2 0.0 0.035 13.0 0.0 1.8 2 0 0 2 2 2 1 AFG1-like ATPase ABC_tran PF00005.27 OEU22763.1 - 0.013 16.1 0.2 0.64 10.5 0.1 3.0 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 OEU22763.1 - 0.024 14.6 0.0 1 9.2 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OEU22763.1 - 0.024 14.9 0.0 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OEU22763.1 - 0.039 13.1 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 OEU22763.1 - 0.078 12.1 0.0 0.6 9.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 OEU22763.1 - 0.09 12.5 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 OEU22763.1 - 0.1 11.9 0.0 0.88 8.9 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 OEU22763.1 - 0.13 12.8 0.0 30 5.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OEU22763.1 - 0.19 11.6 0.1 0.51 10.2 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase HSF_DNA-bind PF00447.17 OEU22764.1 - 3.5e-21 75.6 2.0 4.1e-21 75.4 2.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Clr5 PF14420.6 OEU22764.1 - 0.083 13.1 0.8 0.17 12.1 0.8 1.7 1 1 0 1 1 1 0 Clr5 domain CDC37_M PF08565.11 OEU22768.1 - 3.2e-21 75.4 1.2 1.1e-20 73.8 1.2 1.9 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 OEU22768.1 - 7.7e-13 49.5 12.4 7.7e-13 49.5 12.4 3.5 1 1 2 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 OEU22768.1 - 2.2e-11 43.8 0.0 2.2e-11 43.8 0.0 2.7 4 1 0 4 4 4 1 Cdc37 C terminal domain FlxA PF14282.6 OEU22768.1 - 0.0038 17.2 6.1 0.0038 17.2 6.1 3.0 2 1 1 3 3 3 1 FlxA-like protein DASH_Dad4 PF08650.10 OEU22768.1 - 2.5 8.1 6.2 0.91 9.5 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 TMPIT PF07851.13 OEU22768.1 - 4.7 6.4 9.6 2.4 7.3 3.6 2.2 2 0 0 2 2 2 0 TMPIT-like protein Collagen PF01391.18 OEU22769.1 - 0.14 11.9 0.9 0.23 11.3 0.9 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DNA_pol_A_exo1 PF01612.20 OEU22770.1 - 3e-39 134.5 0.0 3.4e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease ELO PF01151.18 OEU22771.1 - 5.8e-39 134.1 16.1 6.3e-39 134.0 16.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.32 OEU22773.1 - 7.2e-23 80.4 25.8 6.4e-08 33.1 0.6 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22773.1 - 3e-06 27.4 0.1 1.9 8.8 0.1 5.2 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OEU22773.1 - 0.003 16.3 0.1 0.076 11.6 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OEU22773.1 - 0.0067 15.2 4.1 0.55 8.9 0.5 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Atg14 PF10186.9 OEU22774.1 - 1.5e-11 44.0 0.0 8e-11 41.6 0.0 1.8 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 OEU22774.1 - 0.53 10.5 6.9 0.068 13.4 2.2 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Got1 PF04178.12 OEU22775.1 - 1.6e-11 44.6 8.3 2e-11 44.3 8.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PPR_2 PF13041.6 OEU22776.1 - 5.1e-11 42.6 0.1 0.0059 16.8 0.0 7.5 7 2 0 7 7 7 3 PPR repeat family PPR_3 PF13812.6 OEU22776.1 - 5.2e-07 29.7 0.1 0.42 10.7 0.0 7.9 9 1 1 10 10 10 1 Pentatricopeptide repeat domain PPR PF01535.20 OEU22776.1 - 0.00023 21.2 0.6 31 5.1 0.0 6.9 6 1 0 6 6 6 1 PPR repeat ATP13 PF12921.7 OEU22776.1 - 0.0062 16.4 0.4 12 5.8 0.0 3.8 3 1 1 4 4 4 2 Mitochondrial ATPase expression 2-oxoacid_dh PF00198.23 OEU22777.1 - 1.4e-57 194.8 0.1 2.3e-57 194.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OEU22777.1 - 1.8e-18 66.1 1.5 3.9e-18 65.1 1.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OEU22777.1 - 7e-15 55.1 0.5 2.7e-14 53.2 0.5 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OEU22777.1 - 0.036 13.9 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like QRPTase_N PF02749.16 OEU22777.1 - 0.08 13.0 0.1 4.3 7.4 0.0 2.6 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain IlvC PF01450.19 OEU22778.1 - 6.3e-39 133.5 0.5 3e-29 102.2 0.2 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 OEU22778.1 - 6e-33 113.7 0.1 1.1e-32 112.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pox_RNA_pol PF03293.14 OEU22778.1 - 0.15 11.8 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Radical_SAM PF04055.21 OEU22779.1 - 4.5e-06 27.2 0.2 5.1e-05 23.7 0.2 2.4 1 1 1 2 2 2 1 Radical SAM superfamily Hep_59 PF07052.11 OEU22779.1 - 0.00083 20.1 3.8 0.0054 17.5 0.4 2.9 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 MqsA_antitoxin PF15731.5 OEU22779.1 - 0.034 14.2 0.3 0.085 13.0 0.3 1.7 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA MACPF PF01823.19 OEU22779.1 - 0.079 13.0 0.5 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 MAC/Perforin domain VWA_2 PF13519.6 OEU22781.1 - 3.1e-06 27.8 0.1 5.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OEU22781.1 - 1.1e-05 25.7 0.1 2.4e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OEU22781.1 - 2.7e-05 23.6 0.6 0.046 13.1 0.1 2.0 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein AAA_5 PF07728.14 OEU22782.1 - 5.4e-117 386.0 0.0 1.7e-28 99.4 0.0 9.3 7 2 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OEU22782.1 - 5.3e-43 145.6 2.1 2.4e-18 66.3 0.0 5.6 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_7 PF12775.7 OEU22782.1 - 6.6e-33 113.7 1.1 1.5e-06 27.8 0.0 6.5 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 OEU22782.1 - 1.6e-30 106.7 2.3 3.6e-06 27.5 0.3 6.8 6 0 0 6 6 6 5 AAA ATPase domain AAA PF00004.29 OEU22782.1 - 3e-29 102.1 0.0 0.00011 22.7 0.0 6.8 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 OEU22782.1 - 1.8e-24 86.1 0.0 5.3e-10 39.3 0.0 8.4 7 2 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 OEU22782.1 - 1.8e-24 86.1 0.0 0.00045 20.3 0.0 7.4 7 1 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 OEU22782.1 - 3.6e-24 85.8 0.5 0.0044 17.6 0.0 6.9 6 0 0 6 6 6 5 AAA domain AAA_22 PF13401.6 OEU22782.1 - 2e-21 76.7 1.1 0.012 15.9 0.0 7.6 7 1 0 7 7 6 4 AAA domain ABC_tran PF00005.27 OEU22782.1 - 7.6e-21 75.1 1.0 0.005 17.4 0.0 6.6 6 0 0 6 6 6 4 ABC transporter AAA_30 PF13604.6 OEU22782.1 - 1.1e-19 70.9 0.0 0.0018 18.0 0.0 6.9 7 0 0 7 7 7 3 AAA domain AAA_lid_5 PF17865.1 OEU22782.1 - 1.2e-19 70.3 0.1 1.2e-18 67.2 0.0 2.8 4 0 0 4 4 1 1 Midasin AAA lid domain Sigma54_activat PF00158.26 OEU22782.1 - 2.3e-19 69.7 0.0 0.013 15.2 0.0 6.6 6 0 0 6 6 6 3 Sigma-54 interaction domain TsaE PF02367.17 OEU22782.1 - 2.8e-18 66.1 0.1 0.014 15.4 0.0 6.4 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OEU22782.1 - 7.6e-17 61.8 0.2 0.18 12.0 0.0 6.9 6 0 0 6 6 6 4 AAA domain T2SSE PF00437.20 OEU22782.1 - 1.7e-15 56.8 1.1 0.038 13.1 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_29 PF13555.6 OEU22782.1 - 5.7e-15 54.8 0.0 1.2 9.0 0.0 6.7 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_14 PF13173.6 OEU22782.1 - 6.2e-15 55.4 0.0 0.16 12.0 0.0 6.7 6 0 0 6 6 6 3 AAA domain Zeta_toxin PF06414.12 OEU22782.1 - 7.2e-15 54.8 0.0 0.26 10.6 0.0 6.6 6 0 0 6 6 6 3 Zeta toxin RsgA_GTPase PF03193.16 OEU22782.1 - 2e-14 53.8 1.5 0.37 10.7 0.0 7.2 7 0 0 7 7 7 2 RsgA GTPase RNA_helicase PF00910.22 OEU22782.1 - 2.4e-14 53.6 0.4 0.13 12.6 0.0 6.5 6 0 0 6 6 6 1 RNA helicase AAA_28 PF13521.6 OEU22782.1 - 4.1e-14 53.1 8.8 0.077 13.2 0.0 6.9 7 0 0 7 7 6 4 AAA domain AAA_25 PF13481.6 OEU22782.1 - 1.1e-13 51.2 2.2 0.032 13.8 0.0 6.2 6 0 0 6 6 6 3 AAA domain NACHT PF05729.12 OEU22782.1 - 3.4e-13 49.9 1.8 0.28 11.1 0.0 7.4 7 0 0 7 7 7 3 NACHT domain AAA_6 PF12774.7 OEU22782.1 - 3.7e-13 49.1 0.7 0.42 9.5 0.0 7.8 7 0 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 OEU22782.1 - 4.1e-13 49.9 4.9 0.083 13.2 0.0 6.8 7 0 0 7 7 6 2 AAA domain Viral_helicase1 PF01443.18 OEU22782.1 - 9.7e-13 48.4 0.1 0.09 12.5 0.0 5.8 6 0 0 6 6 5 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OEU22782.1 - 1.6e-12 47.8 3.0 0.063 13.2 0.1 6.5 6 0 0 6 6 6 2 Rad17 P-loop domain Mg_chelatase PF01078.21 OEU22782.1 - 3.8e-12 46.0 0.6 7.7 5.8 0.0 8.8 8 1 0 8 8 8 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 OEU22782.1 - 3.9e-12 47.1 9.4 0.072 13.6 0.0 7.2 7 0 0 7 7 6 2 AAA domain ATPase_2 PF01637.18 OEU22782.1 - 1.8e-11 44.4 0.1 0.33 10.8 0.0 6.1 6 1 0 6 6 5 3 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 OEU22782.1 - 2e-11 44.2 0.1 0.012 15.7 0.1 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain SRP54 PF00448.22 OEU22782.1 - 3.2e-11 43.2 0.0 0.16 11.6 0.0 6.1 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OEU22782.1 - 7.3e-11 42.2 0.7 2.9 8.0 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OEU22782.1 - 1.1e-10 41.6 0.2 0.62 9.8 0.0 6.2 6 0 0 6 6 6 1 AAA domain PduV-EutP PF10662.9 OEU22782.1 - 7.1e-10 38.8 3.8 0.085 12.6 0.0 6.3 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 OEU22782.1 - 9.1e-10 38.5 0.2 1.6 8.5 0.0 7.0 6 1 1 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OEU22782.1 - 4.8e-09 35.7 0.3 0.84 8.7 0.1 5.9 6 0 0 6 6 6 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OEU22782.1 - 6.9e-09 35.7 0.4 0.98 9.1 0.0 5.9 6 0 0 6 6 6 1 IstB-like ATP binding protein TniB PF05621.11 OEU22782.1 - 1e-08 34.8 0.0 0.66 9.4 0.0 5.8 6 0 0 6 6 6 2 Bacterial TniB protein NTPase_1 PF03266.15 OEU22782.1 - 1.4e-08 34.8 3.7 4.6 7.1 0.1 6.4 6 0 0 6 6 6 0 NTPase Roc PF08477.13 OEU22782.1 - 1.2e-07 32.0 4.0 4.5 7.5 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 OEU22782.1 - 1.4e-07 30.9 0.0 0.94 8.5 0.0 5.4 6 0 0 6 6 5 1 MCM P-loop domain G-alpha PF00503.20 OEU22782.1 - 5.1e-07 29.2 0.3 0.21 10.7 0.1 5.1 5 0 0 5 5 5 1 G-protein alpha subunit SRPRB PF09439.10 OEU22782.1 - 5.9e-07 29.1 1.1 4.3 6.7 0.0 6.7 7 0 0 7 7 7 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 OEU22782.1 - 1.3e-06 28.5 3.0 0.13 12.3 0.2 4.7 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit cobW PF02492.19 OEU22782.1 - 2.1e-06 27.4 8.2 4.3 6.9 0.0 6.3 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 OEU22782.1 - 2.8e-06 27.3 0.0 24 4.6 0.0 6.1 6 0 0 6 6 6 0 AAA domain dNK PF01712.19 OEU22782.1 - 3.3e-06 27.1 5.7 0.38 10.6 0.0 6.4 7 0 0 7 7 7 1 Deoxynucleoside kinase TrwB_AAD_bind PF10412.9 OEU22782.1 - 4.9e-06 25.7 0.4 1.8 7.4 0.0 5.1 5 0 0 5 5 5 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 OEU22782.1 - 4.9e-06 26.1 0.6 7.5 5.8 0.0 5.0 6 0 0 6 6 4 0 FtsK/SpoIIIE family AAA_8 PF12780.7 OEU22782.1 - 1.1e-05 24.9 4.8 0.34 10.2 0.0 5.4 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 AAA_21 PF13304.6 OEU22782.1 - 2.2e-05 24.4 5.9 0.24 11.2 0.0 6.3 7 0 0 7 7 7 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 OEU22782.1 - 4e-05 23.4 0.0 1.8 8.2 0.0 4.0 3 1 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 OEU22782.1 - 4.3e-05 23.4 0.0 3.6 7.3 0.0 4.7 5 1 0 5 5 4 0 DEAD/DEAH box helicase AAA_15 PF13175.6 OEU22782.1 - 4.9e-05 23.2 3.6 0.37 10.5 0.0 4.6 5 1 0 5 5 4 1 AAA ATPase domain ATPase PF06745.13 OEU22782.1 - 6.1e-05 22.5 0.0 4.6 6.5 0.0 5.0 6 0 0 6 6 5 0 KaiC Septin PF00735.18 OEU22782.1 - 8.4e-05 22.0 3.6 10 5.3 0.0 5.9 7 0 0 7 7 6 0 Septin NB-ARC PF00931.22 OEU22782.1 - 9.6e-05 21.7 0.0 4.6 6.4 0.0 5.2 6 0 0 6 6 6 0 NB-ARC domain AAA_9 PF12781.7 OEU22782.1 - 0.00014 21.0 0.0 1.6 7.8 0.0 4.6 6 0 0 6 6 4 1 ATP-binding dynein motor region Ploopntkinase3 PF18751.1 OEU22782.1 - 0.00097 19.1 0.1 8.8 6.2 0.0 4.7 5 0 0 5 5 5 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 OEU22782.1 - 0.00099 19.0 13.2 15 5.2 0.0 6.5 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein Y_phosphatase PF00102.27 OEU22782.1 - 0.0011 18.6 0.1 0.7 9.4 0.0 3.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Dynamin_N PF00350.23 OEU22782.1 - 0.0013 18.8 1.7 9.5 6.2 0.0 5.4 5 0 0 5 5 5 0 Dynamin family Bac_DnaA PF00308.18 OEU22782.1 - 0.002 18.0 0.1 27 4.5 0.0 4.7 5 0 0 5 5 4 0 Bacterial dnaA protein MobB PF03205.14 OEU22782.1 - 0.0023 17.8 7.5 24 4.8 0.0 6.1 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B SMC_N PF02463.19 OEU22782.1 - 0.004 16.6 0.0 3.3 7.1 0.0 3.7 4 0 0 4 4 3 0 RecF/RecN/SMC N terminal domain FeoB_N PF02421.18 OEU22782.1 - 0.0041 16.7 5.6 18 4.8 0.0 5.4 6 0 0 6 6 5 0 Ferrous iron transport protein B Thymidylate_kin PF02223.17 OEU22782.1 - 0.0057 16.3 0.5 94 2.6 0.0 5.3 6 0 0 6 6 5 0 Thymidylate kinase DAP3 PF10236.9 OEU22782.1 - 0.0076 15.5 1.8 5.1 6.2 0.0 4.2 6 0 0 6 6 3 0 Mitochondrial ribosomal death-associated protein 3 CbiA PF01656.23 OEU22782.1 - 0.014 15.4 3.5 27 4.8 0.0 4.7 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 OEU22782.1 - 0.02 14.6 3.9 7.5 6.2 0.0 4.3 6 0 0 6 6 3 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 OEU22782.1 - 0.028 14.2 0.2 28 4.5 0.0 4.5 5 0 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.21 OEU22782.1 - 0.032 13.9 0.5 26 4.4 0.0 4.5 5 0 0 5 5 4 0 Guanylate kinase MeaB PF03308.16 OEU22782.1 - 0.069 12.1 0.7 50 2.7 0.0 3.7 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DLIC PF05783.11 OEU22782.1 - 0.072 11.9 0.5 47 2.6 0.0 4.1 5 0 0 5 5 4 0 Dynein light intermediate chain (DLIC) tRNA_lig_kinase PF08303.11 OEU22782.1 - 0.098 12.7 0.3 19 5.3 0.0 2.9 2 0 0 2 2 2 0 tRNA ligase kinase domain Adeno_IVa2 PF02456.15 OEU22782.1 - 0.1 11.4 0.3 4.8 5.9 0.0 3.4 4 0 0 4 4 3 0 Adenovirus IVa2 protein UvrD-helicase PF00580.21 OEU22782.1 - 0.11 12.0 9.0 22 4.4 0.0 5.1 5 1 0 6 6 4 0 UvrD/REP helicase N-terminal domain TIP49 PF06068.13 OEU22782.1 - 0.14 11.4 3.1 21 4.1 0.0 4.9 6 1 1 7 7 6 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 OEU22782.1 - 0.17 11.6 0.1 26 4.5 0.0 3.4 3 0 0 3 3 2 0 Cytidylate kinase FliG_N PF14842.6 OEU22782.1 - 0.29 11.7 2.0 44 4.7 0.0 3.3 3 0 0 3 3 3 0 FliG N-terminal domain AAA_17 PF13207.6 OEU22782.1 - 0.93 9.9 10.1 1.2e+02 3.1 0.0 6.4 7 0 0 7 7 7 0 AAA domain Ras PF00071.22 OEU22782.1 - 1.6 8.3 6.8 27 4.3 0.0 4.2 5 0 0 5 5 4 0 Ras family DUF525 PF04379.14 OEU22783.1 - 1.2e-09 38.3 0.0 9.7e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 ApaG domain DUF4637 PF15470.6 OEU22785.1 - 0.058 13.1 1.5 0.15 11.7 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Androgen_recep PF02166.16 OEU22785.1 - 0.2 10.5 5.3 0.28 10.0 5.3 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 OEU22785.1 - 0.29 12.1 11.5 0.31 12.0 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Myc_N PF01056.18 OEU22785.1 - 0.29 11.0 4.6 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Myc amino-terminal region Zip PF02535.22 OEU22785.1 - 6.7 5.8 5.3 0.48 9.6 0.3 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter UL42 PF17638.2 OEU22786.1 - 0.77 9.7 7.9 2.3 8.2 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 GIT_CC PF16559.5 OEU22786.1 - 1.5 8.8 3.6 3.3 7.6 3.6 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PH PF00169.29 OEU22788.1 - 4.5e-07 30.3 0.0 9.4e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OEU22788.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain HTH_54 PF18607.1 OEU22788.1 - 0.015 15.4 0.1 0.03 14.4 0.1 1.6 1 1 0 1 1 1 0 ParA helix turn helix domain Spo7 PF03907.13 OEU22790.1 - 0.14 11.6 2.4 0.13 11.7 0.7 1.7 1 1 1 2 2 2 0 Spo7-like protein RPA43_OB PF17875.1 OEU22790.1 - 0.46 11.1 10.2 6.2 7.5 0.3 3.9 4 0 0 4 4 4 0 RPA43 OB domain in RNA Pol I CPSF100_C PF13299.6 OEU22790.1 - 4.6 7.4 10.6 1.7 8.8 0.0 3.2 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal THF_DHG_CYH_C PF02882.19 OEU22791.1 - 1.4e-41 141.5 0.1 1.7e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OEU22791.1 - 6.9e-12 45.7 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain NAD_binding_7 PF13241.6 OEU22791.1 - 0.053 14.0 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Queuosine_synth PF02547.15 OEU22792.1 - 3e-68 230.3 0.0 3.6e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein Pkinase PF00069.25 OEU22793.1 - 8.8e-40 136.7 0.0 1.3e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22793.1 - 9.5e-17 61.1 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_3 PF13920.6 OEU22793.1 - 5.5e-11 42.1 12.5 1.4e-10 40.8 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.6 OEU22793.1 - 3.1e-07 30.0 0.0 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like MIB_HERC2 PF06701.13 OEU22793.1 - 3.7e-05 23.9 0.0 8.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Mib_herc2 Prok-RING_4 PF14447.6 OEU22793.1 - 7.6e-05 22.5 10.6 0.00016 21.4 10.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PARP PF00644.20 OEU22793.1 - 0.011 15.4 0.0 0.04 13.5 0.0 1.9 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain zf-C3HC4 PF00097.25 OEU22793.1 - 0.045 13.6 12.6 0.11 12.4 12.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) QueH PF02677.14 OEU22794.1 - 3.2e-58 196.7 3.9 3.2e-58 196.7 3.9 1.4 2 0 0 2 2 2 1 Epoxyqueuosine reductase QueH HA PF03457.14 OEU22795.1 - 5.1e-37 126.0 0.9 2.8e-18 66.0 0.1 2.4 2 0 0 2 2 2 2 Helicase associated domain PBP1_TM PF14812.6 OEU22795.1 - 0.73 10.2 6.5 2.8 8.4 2.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OEU22795.1 - 1.4 8.5 8.8 0.21 11.3 4.2 1.8 2 0 0 2 2 2 0 FAM176 family Melittin PF01372.17 OEU22795.1 - 3.4 7.8 10.2 5.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Melittin DUF3307 PF11750.8 OEU22796.1 - 0.079 13.0 0.4 0.13 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) AtpR PF12966.7 OEU22796.1 - 0.089 13.3 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 N-ATPase, AtpR subunit Nefa_Nip30_N PF10187.9 OEU22796.1 - 0.95 9.8 22.9 1.9 8.9 22.9 1.5 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4366 PF14283.6 OEU22796.1 - 1.2 9.2 10.5 19 5.3 11.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) V_ATPase_I PF01496.19 OEU22796.1 - 1.5 6.6 7.6 1.9 6.3 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bud13 PF09736.9 OEU22796.1 - 3.8 7.9 16.3 6.8 7.1 16.3 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex GBP_C PF02841.14 OEU22796.1 - 8.2 5.7 23.6 11 5.4 23.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SURNod19 PF07712.12 OEU22797.1 - 5.9e-11 41.7 10.0 3.7e-09 35.8 0.5 3.4 3 0 0 3 3 3 2 Stress up-regulated Nod 19 ESSS PF10183.9 OEU22797.1 - 0.019 15.2 0.4 0.23 11.7 0.0 2.7 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pox_A9 PF04835.12 OEU22797.1 - 0.44 10.7 1.9 0.94 9.7 1.9 1.5 1 0 0 1 1 1 0 A9 protein conserved region FSAP_sig_propep PF03032.15 OEU22797.1 - 2.1 8.4 7.8 6.9 6.8 0.4 2.7 3 0 0 3 3 3 0 Frog skin active peptide family signal and propeptide Formyl_trans_N PF00551.19 OEU22800.1 - 2.6e-35 121.8 0.0 5.2e-35 120.8 0.0 1.4 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 OEU22800.1 - 8.9e-14 51.6 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain SfsA PF03749.13 OEU22801.1 - 3.3e-18 65.9 0.1 9.4e-13 48.2 0.1 2.1 2 0 0 2 2 2 2 Sugar fermentation stimulation protein RE domain Phage_TTP_13 PF16463.5 OEU22803.1 - 0.0016 18.0 0.1 0.0035 16.9 0.1 1.5 1 0 0 1 1 1 1 Phage tail tube protein family HTH_Tnp_1_2 PF13022.6 OEU22803.1 - 0.0035 17.5 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase WGR PF05406.15 OEU22803.1 - 0.013 15.5 0.2 0.042 13.9 0.2 1.9 1 0 0 1 1 1 0 WGR domain FAM72 PF14976.6 OEU22804.1 - 0.0039 17.3 0.2 0.01 16.0 0.2 1.6 1 0 0 1 1 1 1 FAM72 protein OAD_gamma PF04277.13 OEU22804.1 - 0.037 14.6 0.4 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain C1_1 PF00130.22 OEU22804.1 - 0.12 12.3 2.0 0.27 11.1 2.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ion_trans_N PF08412.10 OEU22804.1 - 0.14 11.8 0.1 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 Ion transport protein N-terminal DUF5068 PF16781.5 OEU22805.1 - 0.00052 19.8 1.6 0.0007 19.4 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5068) SUZ PF12752.7 OEU22805.1 - 0.022 15.5 2.6 0.022 15.5 2.6 2.0 2 1 0 2 2 2 0 SUZ domain DUF1722 PF08349.11 OEU22805.1 - 0.12 12.7 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) IHABP4_N PF16174.5 OEU22805.1 - 0.59 10.7 7.4 0.72 10.4 7.4 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Dicty_REP PF05086.12 OEU22805.1 - 1.2 7.1 4.6 1.3 6.9 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 OEU22806.1 - 0.067 11.5 11.0 0.098 10.9 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 OEU22806.1 - 1.7 9.3 13.6 1.5 9.5 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec62 PF03839.16 OEU22806.1 - 2.7 7.4 7.1 5.2 6.5 7.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Spt20 PF12090.8 OEU22806.1 - 5.5 6.5 12.5 14 5.2 0.4 2.5 2 0 0 2 2 2 0 Spt20 family RrnaAD PF00398.20 OEU22808.1 - 5e-41 140.5 0.0 6.9e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 OEU22808.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) LPD23 PF18838.1 OEU22808.1 - 0.027 14.2 1.5 0.056 13.2 1.5 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 MTS PF05175.14 OEU22808.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 OEU22808.1 - 0.069 13.9 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_5 PF00266.19 OEU22809.1 - 1.3e-27 96.7 0.8 6.4e-21 74.7 0.0 3.9 2 2 0 2 2 2 2 Aminotransferase class-V Psb28 PF03912.14 OEU22809.1 - 0.0031 17.8 0.1 0.33 11.3 0.0 2.5 2 0 0 2 2 2 1 Psb28 protein Rrp44_CSD1 PF17216.3 OEU22809.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain YpmT PF17431.2 OEU22809.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YmpT-like CytadhesinP1 PF12378.8 OEU22810.1 - 0.028 14.6 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein Ferric_reduct PF01794.19 OEU22811.1 - 1e-21 77.3 5.7 1e-21 77.3 5.7 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OEU22811.1 - 1.4e-13 51.2 0.1 6.5e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OEU22811.1 - 1.5e-13 50.8 0.0 4.6e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OEU22811.1 - 2.6e-07 31.3 0.0 2.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SLATT_1 PF18181.1 OEU22811.1 - 0.025 14.5 0.6 0.47 10.4 0.0 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Bac_export_2 PF01312.19 OEU22811.1 - 2.6 7.2 5.8 0.22 10.7 0.4 1.9 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family MARVEL PF01284.23 OEU22811.1 - 5.3 7.1 17.9 0.95 9.5 2.3 3.0 4 0 0 4 4 4 0 Membrane-associating domain VATC PF18716.1 OEU22812.1 - 7.8e-05 22.5 0.2 0.00015 21.6 0.2 1.4 1 0 0 1 1 1 1 Vms1-associating treble clef domain SR-25 PF10500.9 OEU22812.1 - 0.0048 16.5 12.4 0.0064 16.1 12.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-FLZ PF04570.14 OEU22812.1 - 0.015 14.7 0.3 0.025 14.1 0.3 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 BSMAP PF12280.8 OEU22812.1 - 0.018 15.3 0.9 0.022 15.0 0.9 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein Ribosomal_L44 PF00935.19 OEU22812.1 - 0.16 12.5 9.9 0.3 11.6 9.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L44 RR_TM4-6 PF06459.12 OEU22812.1 - 0.17 11.7 9.4 0.21 11.4 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 OEU22812.1 - 0.42 10.7 10.7 0.26 11.4 8.6 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein SAPS PF04499.15 OEU22812.1 - 0.54 9.0 8.2 0.62 8.8 8.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Podoplanin PF05808.11 OEU22812.1 - 0.61 10.2 2.9 0.85 9.7 2.9 1.2 1 0 0 1 1 1 0 Podoplanin DUF1682 PF07946.14 OEU22812.1 - 0.72 9.0 15.8 1.1 8.4 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Nop53 PF07767.11 OEU22812.1 - 1.9 7.8 21.5 2.2 7.6 21.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MDM10 PF12519.8 OEU22812.1 - 2.1 7.1 8.5 2.4 6.9 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CDC45 PF02724.14 OEU22812.1 - 3.1 6.0 13.1 3.6 5.8 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 OEU22812.1 - 4.1 7.5 18.3 5.9 6.9 18.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 OEU22812.1 - 4.3 6.0 7.6 5.1 5.7 7.6 1.1 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.16 OEU22812.1 - 8.7 5.1 6.9 9.8 4.9 6.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 OEU22813.1 - 1e-44 149.6 21.4 1.7e-08 35.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OEU22813.1 - 2.3e-22 79.1 3.4 4.3e-06 26.9 0.2 6.7 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OEU22813.1 - 5.1e-09 36.3 0.1 3.8e-05 23.6 0.1 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A KH_1 PF00013.29 OEU22813.1 - 2.4e-08 33.7 1.9 3.9e-08 33.0 1.9 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 OEU22813.1 - 0.0019 18.1 0.2 0.0036 17.2 0.2 1.4 1 0 0 1 1 1 1 KH domain SLS PF14611.6 OEU22813.1 - 0.038 13.8 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator AreA_N PF07573.11 OEU22814.1 - 0.11 13.2 0.7 0.67 10.6 0.3 2.5 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus DUF572 PF04502.13 OEU22814.1 - 3.4 7.2 16.9 2 7.9 6.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF572) JAB PF01398.21 OEU22815.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SusE PF14292.6 OEU22816.1 - 0.059 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 SusE outer membrane protein Peptidase_C6 PF00851.18 OEU22817.1 - 0.047 12.6 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase adh_short PF00106.25 OEU22818.1 - 7.4e-21 74.5 0.1 3.7e-20 72.2 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU22818.1 - 1.1e-17 64.4 0.1 1.8e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU22818.1 - 1.3e-06 28.4 0.0 4.2e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OEU22818.1 - 0.00078 19.0 0.0 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OEU22818.1 - 0.0036 16.4 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OEU22818.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding SET PF00856.28 OEU22819.1 - 4.6e-11 43.4 0.2 3.2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 SET domain DUF179 PF02622.15 OEU22820.1 - 0.031 14.2 0.2 0.2 11.6 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized ACR, COG1678 zf-C2H2 PF00096.26 OEU22821.1 - 2.9e-07 30.6 23.7 0.015 15.7 0.7 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OEU22821.1 - 5.2e-06 26.9 28.1 0.12 13.3 0.3 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger PHD PF00628.29 OEU22821.1 - 0.00041 20.2 12.0 0.00041 20.2 12.0 4.8 5 0 0 5 5 5 1 PHD-finger GAGA PF09237.11 OEU22821.1 - 0.55 10.1 0.0 0.55 10.1 0.0 3.3 4 0 0 4 4 4 0 GAGA factor zf-C2H2_6 PF13912.6 OEU22821.1 - 0.59 10.2 13.4 2.2 8.4 0.5 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 OEU22821.1 - 1.9 8.0 12.1 53 3.4 0.1 4.9 4 0 0 4 4 4 0 zinc-ribbon domain CHCH PF06747.13 OEU22822.1 - 0.0018 18.4 4.2 0.0018 18.4 4.2 1.7 2 0 0 2 2 2 1 CHCH domain NDUF_B7 PF05676.13 OEU22822.1 - 0.0095 15.6 2.3 0.016 14.9 2.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ZirS_C PF16583.5 OEU22822.1 - 0.051 13.2 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Mnd1 PF03962.15 OEU22823.1 - 1.9e-19 69.7 2.9 2.9e-19 69.1 0.1 2.4 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 OEU22823.1 - 3.5e-16 59.0 0.8 3.5e-16 59.0 0.8 2.3 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 OEU22823.1 - 0.015 15.7 0.6 0.029 14.7 0.1 1.8 2 0 0 2 2 2 0 Penicillinase repressor ABC_tran_CTD PF16326.5 OEU22823.1 - 0.033 14.4 6.9 0.033 14.4 6.9 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Acetyltransf_1 PF00583.25 OEU22824.1 - 8.9e-11 42.1 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU22824.1 - 2.3e-09 37.5 0.0 5.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU22824.1 - 4e-06 26.8 0.0 7.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OEU22824.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BHD_3 PF10405.9 OEU22825.1 - 0.046 14.1 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 3 CHMI PF02962.15 OEU22825.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase NAD_binding_1 PF00175.21 OEU22826.1 - 8.6e-06 26.4 0.0 0.0018 18.9 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OEU22826.1 - 0.00011 22.3 0.0 0.00021 21.5 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FlgM PF04316.13 OEU22827.1 - 0.084 13.3 4.4 3.1 8.3 0.0 3.8 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM TFIIA PF03153.13 OEU22827.1 - 0.79 9.6 35.3 0.6 10.1 15.2 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Endonuclease_NS PF01223.23 OEU22828.1 - 3.1e-44 151.5 0.0 3.6e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Snf7 PF03357.21 OEU22829.1 - 0.00012 21.7 19.1 0.00012 21.7 19.1 4.5 3 2 2 5 5 5 2 Snf7 WAP PF00095.21 OEU22830.1 - 0.0018 18.6 5.2 0.0032 17.8 5.2 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF2076 PF09849.9 OEU22830.1 - 0.034 14.2 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PPR PF01535.20 OEU22831.1 - 0.00028 20.9 0.1 3 8.3 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 OEU22831.1 - 0.13 12.5 0.7 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family PALP PF00291.25 OEU22832.1 - 1.2e-55 189.0 0.0 8e-55 186.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Init_tRNA_PT PF04179.12 OEU22832.1 - 0.074 13.4 0.0 0.62 10.4 0.0 2.2 2 0 0 2 2 2 0 Rit1 DUSP-like domain eIF3_subunit PF08597.10 OEU22833.1 - 4e-21 76.0 35.8 8.7e-21 74.9 35.8 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit Peptidase_S8 PF00082.22 OEU22834.1 - 2e-16 60.1 0.0 5.2e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Tyr_Deacylase PF02580.16 OEU22835.1 - 2.3e-48 164.4 0.0 2.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2039 PF10217.9 OEU22837.1 - 0.09 13.1 5.2 0.09 13.1 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) PP2C PF00481.21 OEU22838.1 - 2.6e-21 76.4 0.0 2.7e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C BNIP2 PF12496.8 OEU22841.1 - 0.59 10.6 5.8 0.99 9.8 5.8 1.4 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 UPF0176_N PF17773.1 OEU22842.1 - 7.5e-23 80.7 0.0 1.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 OEU22842.1 - 8e-15 55.0 9.8 1.6e-14 54.0 9.8 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 OEU22842.1 - 9.1e-06 26.2 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Chorion_2 PF03964.15 OEU22843.1 - 3.8 8.4 10.4 0.77 10.6 1.0 2.5 3 0 0 3 3 3 0 Chorion family 2 SR-25 PF10500.9 OEU22843.1 - 9.2 5.8 18.3 3.8 7.1 4.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3054 PF11255.8 OEU22844.1 - 2.1e-19 70.0 0.9 2.6e-19 69.8 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) Abhydrolase_1 PF00561.20 OEU22846.1 - 5.1e-13 49.3 0.0 7.2e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OEU22846.1 - 6.6e-11 43.2 0.0 1e-10 42.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU22846.1 - 2.6e-07 30.2 0.0 1e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OEU22846.1 - 0.043 13.9 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 OEU22846.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF5053 PF16476.5 OEU22849.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) FGGY_C PF02782.16 OEU22851.1 - 2.6e-18 66.5 0.0 4.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OEU22851.1 - 4.1e-07 29.8 0.0 1.1e-05 25.1 0.0 2.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Sigma70_r2 PF04542.14 OEU22852.1 - 3.4e-10 39.5 0.0 9.8e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 OEU22852.1 - 2.3e-08 33.4 0.2 7.2e-07 28.6 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 PPR_2 PF13041.6 OEU22853.1 - 4.8e-29 100.3 0.0 1.1e-07 31.9 0.0 7.7 6 1 1 7 7 7 6 PPR repeat family PPR_1 PF12854.7 OEU22853.1 - 9.5e-17 60.4 0.1 7.9e-05 22.3 0.0 9.0 10 0 0 10 10 10 2 PPR repeat PPR_3 PF13812.6 OEU22853.1 - 3.7e-14 52.6 0.1 0.17 12.0 0.0 8.1 7 1 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.20 OEU22853.1 - 7.3e-14 51.0 9.7 0.031 14.5 0.0 10.2 10 1 0 10 10 10 4 PPR repeat PPR_long PF17177.4 OEU22853.1 - 3.6e-08 33.0 0.9 0.022 14.1 0.0 4.7 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP Annexin_like PF18411.1 OEU22853.1 - 0.096 13.0 0.0 10 6.4 0.0 2.9 2 0 0 2 2 2 0 Annexin-like domain FKBP_C PF00254.28 OEU22854.1 - 1.8e-09 37.8 0.0 1.2e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase GFO_IDH_MocA PF01408.22 OEU22855.1 - 1.2e-14 55.2 0.0 1.8e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold G6PD_N PF00479.22 OEU22855.1 - 0.0067 17.1 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OEU22855.1 - 0.027 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain TLC PF03219.14 OEU22858.1 - 2.7e-18 66.0 17.0 5.9e-11 41.8 8.8 2.4 2 1 0 2 2 2 2 TLC ATP/ADP transporter MFS_1 PF07690.16 OEU22858.1 - 1.6e-06 27.3 24.8 6.1e-05 22.1 9.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FixQ PF05545.11 OEU22858.1 - 5.1 7.2 9.2 25 4.9 0.2 3.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Sporozoite_P67 PF05642.11 OEU22858.1 - 7.5 4.5 7.3 12 3.8 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA_edit PF04073.15 OEU22860.1 - 5.6e-09 36.1 0.0 4.6e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_L28e PF01778.17 OEU22861.1 - 5.4e-33 114.2 1.3 5.4e-33 114.2 1.3 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 OEU22861.1 - 3.2e-25 88.6 20.9 3.7e-25 88.4 18.6 2.3 2 1 0 2 2 2 1 Mak16 protein C-terminal region XRN_M PF17846.1 OEU22861.1 - 0.54 9.1 6.2 0.74 8.7 6.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RNA_pol_3_Rpc31 PF11705.8 OEU22861.1 - 0.6 10.3 16.3 1.4 9.1 16.2 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 adh_short_C2 PF13561.6 OEU22862.1 - 3.9e-45 154.2 0.6 1.2e-44 152.6 0.1 1.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU22862.1 - 8.7e-33 113.4 1.0 1.4e-31 109.5 1.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU22862.1 - 1.3e-10 41.5 0.0 4.3e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OEU22862.1 - 0.023 13.8 0.1 0.65 9.1 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MetW PF07021.12 OEU22863.1 - 0.021 14.4 0.2 0.051 13.2 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW MGDG_synth PF06925.11 OEU22864.1 - 0.034 14.2 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Pet100 PF09803.9 OEU22865.1 - 1.6e-09 38.2 1.1 2e-09 37.8 1.1 1.1 1 0 0 1 1 1 1 Pet100 Smg4_UPF3 PF03467.15 OEU22865.1 - 0.013 15.5 0.3 0.014 15.4 0.3 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family PseudoU_synth_1 PF01416.20 OEU22866.1 - 8.7e-27 93.7 0.0 1.4e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase HA PF03457.14 OEU22867.1 - 4.9e-43 145.3 3.3 1.8e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 Helicase associated domain Melittin PF01372.17 OEU22867.1 - 2.4 8.3 4.5 33 4.7 0.5 2.6 2 0 0 2 2 2 0 Melittin Metallophos PF00149.28 OEU22868.1 - 4.6e-15 56.7 0.1 8.8e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Epimerase_2 PF02350.19 OEU22868.1 - 0.096 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Mito_carr PF00153.27 OEU22869.1 - 1.7e-13 50.3 0.2 6.1e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein DUF2039 PF10217.9 OEU22870.1 - 1.4e-23 83.0 8.9 1.4e-23 83.0 8.9 2.5 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2039) DZR PF12773.7 OEU22870.1 - 0.78 9.8 10.5 4.8 7.3 10.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-HC5HC2H PF13771.6 OEU22870.1 - 2.2 8.6 12.4 10 6.5 12.5 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OEU22870.1 - 2.9 8.1 10.0 12 6.1 10.4 1.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain FYVE PF01363.21 OEU22870.1 - 3.4 7.9 12.9 2.5e+02 1.9 3.1 2.6 1 1 1 2 2 2 0 FYVE zinc finger Trypsin PF00089.26 OEU22871.1 - 2.7e-41 141.8 0.0 3e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OEU22871.1 - 0.0016 19.4 0.0 0.0039 18.1 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Voltage_CLC PF00654.20 OEU22872.1 - 7.2e-95 318.2 12.0 7.2e-95 318.2 12.0 1.7 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 OEU22872.1 - 1.1e-07 32.2 0.0 4.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 CBS domain 2OG-FeII_Oxy_2 PF13532.6 OEU22873.1 - 6.2e-16 59.2 0.0 9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAS20 PF02064.15 OEU22873.1 - 0.5 10.5 3.5 1 9.5 3.5 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Ank PF00023.30 OEU22874.1 - 0.12 12.9 0.0 30 5.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DUF4568 PF15132.6 OEU22874.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) FTCD_N PF07837.12 OEU22875.1 - 1.1e-13 51.3 0.0 1.3e-12 47.9 0.0 2.3 1 1 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain Thioredoxin PF00085.20 OEU22876.1 - 8e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU22876.1 - 8.5e-06 25.9 0.2 3.3e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OEU22876.1 - 0.00035 21.0 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OEU22876.1 - 0.0048 16.8 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family DUF1415 PF07209.12 OEU22877.1 - 1.4e-11 44.5 0.0 2.3e-07 30.7 0.0 3.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1415) SR-25 PF10500.9 OEU22877.1 - 0.36 10.4 8.9 3.5 7.2 0.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DBINO PF13892.6 OEU22878.1 - 0.082 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 DNA-binding domain Isochorismatase PF00857.20 OEU22879.1 - 0.048 13.8 0.1 8.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Isochorismatase family DUF5431 PF17496.2 OEU22879.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5431) PHD PF00628.29 OEU22880.1 - 2e-12 46.8 3.3 2.2e-12 46.7 3.3 1.0 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OEU22880.1 - 0.0011 18.7 0.7 0.0012 18.4 0.7 1.0 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 OEU22880.1 - 0.0017 17.9 2.2 0.0021 17.6 0.1 2.0 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 OEU22880.1 - 0.035 14.4 2.8 0.049 14.0 2.8 1.3 1 0 0 1 1 1 0 C1 domain PWWP PF00855.17 OEU22881.1 - 4.3e-09 36.7 0.3 4.3e-09 36.7 0.3 2.2 2 0 0 2 2 2 1 PWWP domain DUF4428 PF14471.6 OEU22881.1 - 0.087 12.8 1.3 0.21 11.5 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) His_Phos_1 PF00300.22 OEU22883.1 - 4.3e-10 39.6 0.5 1.5e-09 37.8 0.5 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) W2 PF02020.18 OEU22883.1 - 0.053 13.7 1.1 0.13 12.4 0.5 1.9 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon LRR_8 PF13855.6 OEU22887.1 - 0.016 15.0 3.2 0.16 11.7 0.2 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 OEU22887.1 - 0.11 13.0 2.8 0.43 11.1 0.7 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) AAA_12 PF13087.6 OEU22889.1 - 9.1e-06 25.4 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Pyr_redox_3 PF13738.6 OEU22890.1 - 3.1e-19 69.3 0.0 7.7e-17 61.5 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OEU22890.1 - 4.5e-16 58.4 0.2 9e-14 50.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OEU22890.1 - 4.2e-15 55.7 0.0 2.8e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OEU22890.1 - 1.7e-14 53.8 0.2 2.4e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OEU22890.1 - 8.6e-07 28.9 0.0 0.011 15.3 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU22890.1 - 3.1e-05 24.1 0.0 0.00016 21.8 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OEU22890.1 - 3.2e-05 23.2 0.1 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OEU22890.1 - 0.0019 17.3 0.0 0.46 9.5 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 OEU22890.1 - 0.003 17.6 0.5 0.27 11.2 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DUF719 PF05334.13 OEU22890.1 - 0.012 15.9 0.9 0.02 15.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) HI0933_like PF03486.14 OEU22890.1 - 0.013 14.3 0.0 0.63 8.7 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 OEU22890.1 - 0.028 15.0 0.2 4.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OEU22890.1 - 0.04 14.2 1.1 2.5 8.4 0.0 3.3 4 0 0 4 4 4 0 TrkA-N domain Thi4 PF01946.17 OEU22890.1 - 0.079 12.2 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 OEU22890.1 - 0.11 11.7 0.2 0.49 9.6 0.1 2.2 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.20 OEU22890.1 - 0.14 12.3 0.0 10 6.2 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PAP_central PF04928.17 OEU22891.1 - 5.9e-59 199.0 0.0 7.2e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OEU22891.1 - 1.3e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OEU22891.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain CN_hydrolase PF00795.22 OEU22892.1 - 9e-46 156.3 0.0 1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HA PF03457.14 OEU22893.1 - 9.9e-13 48.2 0.1 9.9e-13 48.2 0.1 2.9 3 1 0 3 3 3 1 Helicase associated domain Brr6_like_C_C PF10104.9 OEU22893.1 - 0.65 9.8 0.0 0.65 9.8 0.0 1.9 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF966 PF06136.13 OEU22893.1 - 4.4 6.9 19.2 6.3 6.4 19.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF5401 PF17380.2 OEU22893.1 - 6.3 4.7 40.1 8.5 4.3 40.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Plus-3 PF03126.18 OEU22894.1 - 2.1e-20 73.2 0.0 8e-20 71.4 0.0 2.1 1 0 0 1 1 1 1 Plus-3 domain SUR7 PF06687.12 OEU22896.1 - 0.2 11.3 2.9 0.26 10.9 2.9 1.1 1 0 0 1 1 1 0 SUR7/PalI family Methyltransf_16 PF10294.9 OEU22897.1 - 8.5e-08 32.1 0.1 1.9e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OEU22897.1 - 2.9e-05 23.6 0.4 4.8e-05 22.9 0.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) THF_DHG_CYH_C PF02882.19 OEU22897.1 - 0.00011 21.6 0.2 0.00022 20.6 0.2 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Met_10 PF02475.16 OEU22897.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein AlaDh_PNT_C PF01262.21 OEU22897.1 - 0.0018 17.6 0.1 0.0034 16.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OEU22897.1 - 0.032 15.0 0.1 0.088 13.5 0.1 1.8 1 1 1 2 2 2 0 Methyltransferase domain UPF0146 PF03686.13 OEU22897.1 - 0.037 13.9 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Thioredoxin_8 PF13905.6 OEU22898.1 - 1.9e-26 92.2 0.0 2.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OEU22898.1 - 6.1e-09 35.8 0.0 2.4e-07 30.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU22898.1 - 2.3e-05 24.8 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU22898.1 - 2.7e-05 23.9 0.0 0.00079 19.2 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 OEU22898.1 - 0.00014 21.7 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OEU22898.1 - 0.00045 20.0 0.0 0.0005 19.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin NADH_4Fe-4S PF10589.9 OEU22898.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Glyco_transf_8C PF08437.10 OEU22898.1 - 0.12 12.5 0.3 0.47 10.6 0.3 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Transglut_core PF01841.19 OEU22899.1 - 2.4e-11 44.1 0.0 4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 OEU22899.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain zf-RRN7 PF11781.8 OEU22899.1 - 7.2 6.4 8.9 0.64 9.7 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Cu_bind_like PF02298.17 OEU22900.1 - 0.08 13.0 0.9 0.52 10.4 0.9 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Chorein_N PF12624.7 OEU22901.1 - 0.011 15.9 0.1 0.087 12.9 0.0 2.5 3 0 0 3 3 3 0 N-terminal region of Chorein or VPS13 Endonuclease_1 PF04231.13 OEU22902.1 - 5e-35 121.3 0.0 6e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease I DUF469 PF04320.14 OEU22903.1 - 0.41 11.5 4.4 2.4 9.1 1.5 2.5 2 1 0 2 2 2 0 Protein with unknown function (DUF469) RXLR PF16810.5 OEU22903.1 - 1.2 9.6 7.7 0.14 12.6 0.4 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity EMC3_TMCO1 PF01956.16 OEU22903.1 - 4.1 7.1 4.8 19 5.0 0.9 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PSK_trans_fac PF07704.11 OEU22903.1 - 9.5 7.1 12.2 16 6.3 4.4 3.4 3 1 1 4 4 4 0 Rv0623-like transcription factor JmjC PF02373.22 OEU22904.1 - 2.6e-10 40.7 7.3 2.6e-10 40.7 7.3 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OEU22904.1 - 6.3e-07 29.4 16.4 2.1e-06 27.6 16.4 1.9 1 1 0 1 1 1 1 Cupin-like domain MRI PF15325.6 OEU22904.1 - 6.3 7.9 8.2 2.2 9.4 0.4 3.5 2 1 1 3 3 3 0 Modulator of retrovirus infection Helicase_C PF00271.31 OEU22906.1 - 1.2e-16 61.0 0.0 2.5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OEU22906.1 - 7.2e-14 51.9 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OEU22906.1 - 6.9e-12 45.6 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 OEU22906.1 - 7e-08 32.4 0.0 2.7e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OEU22906.1 - 0.0017 18.7 0.1 0.0053 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU22906.1 - 0.0086 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OEU22906.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 OEU22906.1 - 0.011 16.2 0.0 0.031 14.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 OEU22906.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OEU22906.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 OEU22906.1 - 0.028 14.4 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 OEU22906.1 - 0.031 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 OEU22906.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OEU22906.1 - 0.063 13.3 0.2 2 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OEU22906.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 OEU22906.1 - 0.098 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 OEU22906.1 - 0.19 12.2 0.2 0.73 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RXT2_N PF08595.11 OEU22907.1 - 0.0027 17.8 0.8 0.0069 16.4 0.3 1.9 2 0 0 2 2 2 1 RXT2-like, N-terminal Cortexin PF11057.8 OEU22909.1 - 0.069 13.0 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Cortexin of kidney SpoU_methylase PF00588.19 OEU22910.1 - 1.2e-20 74.1 0.0 5.4e-18 65.5 0.0 2.5 2 1 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OEU22910.1 - 5.9e-10 39.3 0.0 7.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding CENP-B_dimeris PF09026.10 OEU22910.1 - 0.085 13.3 8.9 0.32 11.4 0.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 OEU22910.1 - 0.22 11.8 4.4 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sel1 PF08238.12 OEU22911.1 - 3.7e-24 84.6 0.2 1.3e-09 38.4 0.2 4.1 4 0 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 OEU22911.1 - 0.0039 17.8 2.3 0.63 10.7 1.7 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU22911.1 - 0.0083 16.3 1.6 0.034 14.4 0.5 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OEU22911.1 - 0.056 14.1 1.9 12 6.8 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP-synt_F PF01990.17 OEU22911.1 - 0.069 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit TPR_19 PF14559.6 OEU22911.1 - 0.62 10.6 4.7 0.62 10.6 0.9 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat COPIIcoated_ERV PF07970.12 OEU22912.1 - 1.6e-29 103.4 0.8 2.9e-29 102.5 0.8 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OEU22912.1 - 1.3e-23 83.1 0.1 2.5e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 OEU22912.1 - 3.1e-19 68.9 0.1 5.8e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2461 PF09365.10 OEU22912.1 - 0.013 15.5 0.1 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) RCC1 PF00415.18 OEU22913.1 - 6.7e-98 321.2 32.6 1.1e-15 58.0 0.5 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OEU22913.1 - 1.5e-45 152.1 42.3 1.2e-08 34.5 0.3 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OEU22913.1 - 1.3e-22 80.1 0.3 2.6e-22 79.1 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1921 PF09081.10 OEU22913.1 - 0.0022 18.2 1.6 5.3 7.4 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1921) DUF3342 PF11822.8 OEU22913.1 - 0.004 17.3 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BACK PF07707.15 OEU22913.1 - 0.011 15.8 0.1 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch Hira PF07569.11 OEU22913.1 - 0.012 15.4 0.4 23 4.6 0.0 4.2 5 0 0 5 5 5 0 TUP1-like enhancer of split Kelch_6 PF13964.6 OEU22913.1 - 0.16 12.3 5.4 3.1 8.2 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 OEU22913.1 - 0.37 10.9 8.8 5 7.3 0.3 4.5 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.25 OEU22913.1 - 4.4 7.0 6.1 9.2 5.9 0.1 2.9 3 0 0 3 3 3 0 Kelch motif TPR_12 PF13424.6 OEU22914.1 - 2.9e-32 110.8 8.8 7.8e-12 45.3 0.9 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OEU22914.1 - 3.2e-25 87.2 4.2 7.3e-06 25.7 0.2 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OEU22914.1 - 1.3e-20 72.3 4.0 0.00039 20.1 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OEU22914.1 - 3.2e-17 61.2 9.6 0.028 14.5 0.0 7.3 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU22914.1 - 5.3e-16 57.4 7.0 0.013 15.7 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU22914.1 - 2.5e-14 52.2 3.0 0.046 13.8 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OEU22914.1 - 1.9e-08 34.8 6.8 0.00039 21.0 1.3 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OEU22914.1 - 7e-06 25.6 0.7 1.3e-05 24.8 0.7 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 OEU22914.1 - 2.4e-05 24.8 10.5 0.9 10.5 0.3 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OEU22914.1 - 0.00012 22.5 1.0 2.5 8.7 0.2 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU22914.1 - 0.00071 20.0 6.4 18 6.2 0.2 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 OEU22914.1 - 0.0027 17.8 2.3 0.15 12.1 0.2 3.5 1 1 3 4 4 4 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 OEU22914.1 - 0.0065 16.9 4.2 14 6.1 0.5 4.3 2 2 2 4 4 4 0 Bacterial transcriptional activator domain PPR PF01535.20 OEU22914.1 - 0.0083 16.3 2.0 36 4.9 0.0 4.8 6 0 0 6 6 4 0 PPR repeat DUF2225 PF09986.9 OEU22914.1 - 0.01 15.6 0.2 0.067 12.9 0.0 2.3 2 1 1 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.9 OEU22914.1 - 0.033 13.7 0.1 25 4.4 0.0 4.0 4 0 0 4 4 4 0 SHNi-TPR ANAPC5 PF12862.7 OEU22914.1 - 0.035 14.2 0.2 1.9 8.6 0.0 3.2 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF5113 PF17140.4 OEU22914.1 - 0.04 13.7 0.7 67 3.2 0.1 4.2 4 2 0 4 4 4 0 Domain of unknown function (DUF5113) TPR_11 PF13414.6 OEU22914.1 - 0.066 12.9 1.7 29 4.5 0.0 4.3 4 1 1 5 5 5 0 TPR repeat V-SNARE_C PF12352.8 OEU22914.1 - 0.071 13.4 0.0 3.2 8.1 0.0 3.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus CREPT PF16566.5 OEU22914.1 - 0.15 12.2 1.5 0.33 11.1 1.5 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Clathrin PF00637.20 OEU22914.1 - 0.27 11.1 5.4 0.31 10.9 0.4 3.2 4 0 0 4 4 3 0 Region in Clathrin and VPS DUF1980 PF09323.10 OEU22915.1 - 0.081 12.8 0.9 0.36 10.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Fasciclin PF02469.22 OEU22917.1 - 4.9e-18 65.6 0.0 1.2e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Peptidase_M1 PF01433.20 OEU22918.1 - 0.032 13.8 0.4 0.059 12.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase family M1 domain Esterase PF00756.20 OEU22919.1 - 5.9e-21 75.2 0.0 1.1e-20 74.3 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OEU22919.1 - 3.6e-05 23.1 0.0 7.4e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OEU22919.1 - 3.7e-05 23.3 0.0 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 OEU22919.1 - 0.0031 16.5 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_3 PF07859.13 OEU22919.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OEU22919.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OEU22919.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_GDSL_2 PF13472.6 OEU22920.1 - 2.8e-12 47.4 0.0 7.8e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OEU22920.1 - 0.0005 20.1 0.0 0.0059 16.6 0.0 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Methyltransf_21 PF05050.12 OEU22921.1 - 2.6e-07 30.8 0.2 8.9e-07 29.1 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase FkbM domain TehB PF03848.14 OEU22921.1 - 0.0036 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Fumble PF03630.14 OEU22922.1 - 2.3e-104 349.1 0.4 3e-104 348.8 0.4 1.1 1 0 0 1 1 1 1 Fumble DUF1943 PF09172.11 OEU22922.1 - 0.03 13.6 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) LRR_8 PF13855.6 OEU22923.1 - 1.7e-12 46.9 13.5 6.5e-05 22.6 0.6 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OEU22923.1 - 0.00014 22.2 1.8 0.00014 22.2 1.8 4.2 1 1 3 5 5 5 2 Leucine Rich repeats (2 copies) CBM_6 PF03422.15 OEU22923.1 - 0.0002 21.6 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 OEU22923.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 DUF5010 C-terminal domain LRR_6 PF13516.6 OEU22923.1 - 0.014 15.4 5.3 7.3 6.9 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OEU22923.1 - 0.61 10.9 11.1 52 5.0 0.1 5.8 7 0 0 7 7 7 0 Leucine Rich Repeat Tubulin PF00091.25 OEU22924.1 - 3.5e-71 239.5 0.1 7.6e-71 238.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OEU22924.1 - 1.3e-39 135.3 0.2 1.8e-39 134.7 0.2 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OEU22924.1 - 2.8e-05 24.4 0.0 6.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OEU22924.1 - 0.0046 16.7 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OEU22924.1 - 0.069 12.3 0.1 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Tubulin like TraB PF01963.17 OEU22926.1 - 1.1e-15 58.3 0.0 1.4e-07 31.7 0.1 2.4 2 1 0 2 2 2 2 TraB family Cwf_Cwc_15 PF04889.12 OEU22928.1 - 0.1 12.3 3.6 0.15 11.7 3.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein 2OG-FeII_Oxy_3 PF13640.6 OEU22929.1 - 4.3e-06 27.5 0.0 7.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OEU22929.1 - 0.0042 17.7 0.0 0.009 16.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 OEU22929.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Peptidase_S8 PF00082.22 OEU22930.1 - 2.7e-34 118.8 4.3 6.1e-34 117.6 4.3 1.6 1 0 0 1 1 1 1 Subtilase family Polyoma_coat2 PF00761.20 OEU22930.1 - 0.13 11.9 0.2 0.61 9.7 0.1 2.1 2 0 0 2 2 2 0 Polyomavirus coat protein DDE_Tnp_1_7 PF13843.6 OEU22933.1 - 8.9e-15 54.8 1.0 4e-14 52.7 1.0 2.0 1 1 0 1 1 1 1 Transposase IS4 Rieske PF00355.26 OEU22934.1 - 5.7e-13 48.6 0.0 8.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WHAMM-JMY_N PF15920.5 OEU22934.1 - 0.00015 21.5 0.2 0.00027 20.7 0.2 1.3 1 0 0 1 1 1 1 N-terminal of Junction-mediating and WASP homolog-associated FKBP_C PF00254.28 OEU22937.1 - 2.1e-17 63.2 0.1 1.9e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 OEU22937.1 - 1.3e-06 27.5 4.8 0.0013 18.2 0.6 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU22937.1 - 2.3e-05 23.9 2.3 0.011 15.7 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OEU22937.1 - 0.00014 22.2 3.0 0.025 15.0 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OEU22937.1 - 0.00041 19.7 4.3 0.097 12.2 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OEU22937.1 - 0.014 15.2 5.8 1.9 8.4 0.5 2.9 3 0 0 3 3 3 0 EF-hand domain pair RNA_pol_3_Rpc31 PF11705.8 OEU22937.1 - 0.1 12.8 9.5 0.16 12.2 9.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HSP20 PF00011.21 OEU22938.1 - 7.8e-14 51.7 2.2 6e-13 48.8 1.2 2.5 2 1 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OEU22938.1 - 1.7e-07 30.7 0.1 3.2e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 OEU22938.1 - 0.06 13.4 0.2 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 GvpH V_ATPase_I PF01496.19 OEU22938.1 - 0.26 9.1 8.4 0.28 9.0 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PsbU PF06514.11 OEU22938.1 - 0.45 10.5 0.1 0.45 10.5 0.1 2.5 3 0 0 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) 7tm_3 PF00003.22 OEU22939.1 - 2e-35 122.7 23.9 2.8e-35 122.2 23.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_4 PF13407.6 OEU22939.1 - 2.9e-15 56.5 0.0 3.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF179 PF02622.15 OEU22940.1 - 7.2e-13 48.8 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 CitMHS PF03600.16 OEU22941.1 - 9.1e-47 159.7 38.4 1.5e-38 132.7 8.1 2.2 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 OEU22941.1 - 2.4e-16 59.3 0.6 2.4e-08 33.7 0.2 2.4 2 0 0 2 2 2 2 TrkA-C domain Pkinase PF00069.25 OEU22942.1 - 9.4e-20 71.1 0.0 1.9e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU22942.1 - 5.5e-05 22.6 0.0 0.00026 20.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OEU22942.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OEU22942.1 - 0.042 12.6 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OEU22942.1 - 0.049 13.6 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2890 PF11081.8 OEU22943.1 - 0.018 15.2 0.8 0.029 14.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Androgen_recep PF02166.16 OEU22943.1 - 0.18 10.6 2.3 0.28 10.0 2.3 1.1 1 0 0 1 1 1 0 Androgen receptor DIOX_N PF14226.6 OEU22944.1 - 3.8e-14 53.4 0.0 7.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OEU22944.1 - 6.3e-07 29.8 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 OEU22944.1 - 0.0092 15.8 0.1 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Sulfotransfer_2 PF03567.14 OEU22945.1 - 2.8e-17 63.5 0.0 1.5e-16 61.1 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Metallophos_C PF14008.6 OEU22946.1 - 1.8e-09 38.3 0.1 4e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 OEU22946.1 - 5.9e-07 30.2 1.6 8.5e-07 29.7 1.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_C50 PF03568.17 OEU22947.1 - 1.5e-44 152.7 0.0 3.4e-44 151.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 OEU22947.1 - 0.00019 21.0 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 CHAT domain DUF5082 PF16888.5 OEU22950.1 - 0.00018 21.8 11.5 0.00081 19.7 5.1 3.3 1 1 1 3 3 3 2 Domain of unknown function (DUF5082) Spc7 PF08317.11 OEU22950.1 - 0.00059 18.8 13.2 0.039 12.8 1.6 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OEU22950.1 - 0.005 16.9 15.0 0.095 12.7 4.9 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 OEU22950.1 - 0.0064 16.9 6.2 1.8 9.0 0.1 4.0 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) Filament PF00038.21 OEU22950.1 - 0.0072 15.9 11.6 0.011 15.3 1.5 2.4 2 0 0 2 2 2 1 Intermediate filament protein DUF4618 PF15397.6 OEU22950.1 - 0.015 14.7 7.5 0.45 9.9 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.12 OEU22950.1 - 0.022 14.8 13.8 0.15 12.1 4.7 2.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 OEU22950.1 - 0.029 14.3 9.7 1.3 9.0 1.5 3.2 2 1 0 2 2 2 0 Prefoldin subunit She9_MDM33 PF05546.11 OEU22950.1 - 0.042 13.6 5.9 0.047 13.5 0.8 2.5 1 1 1 2 2 2 0 She9 / Mdm33 family TMPIT PF07851.13 OEU22950.1 - 0.067 12.4 7.8 0.49 9.6 1.8 2.3 1 1 1 2 2 2 0 TMPIT-like protein GTP-bdg_M PF16360.5 OEU22950.1 - 0.091 13.4 1.6 12 6.6 0.1 3.4 2 2 1 3 3 3 0 GTP-binding GTPase Middle Region HIP1_clath_bdg PF16515.5 OEU22950.1 - 0.13 12.9 6.6 8.5 7.1 2.0 3.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CC2-LZ PF16516.5 OEU22950.1 - 0.23 11.8 4.6 7.2 7.0 0.3 3.0 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BRE1 PF08647.11 OEU22950.1 - 0.39 10.8 7.4 7.1 6.8 0.1 3.6 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase LOH1CR12 PF10158.9 OEU22950.1 - 0.42 10.6 3.9 4.3 7.4 0.3 2.7 1 1 1 3 3 3 0 Tumour suppressor protein Mod_r PF07200.13 OEU22950.1 - 0.59 10.2 9.5 0.97 9.5 2.1 2.8 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF641 PF04859.12 OEU22950.1 - 0.63 10.4 5.4 0.89 9.9 0.4 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 OEU22950.1 - 0.9 9.7 16.3 1.1 9.4 2.8 3.7 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 OEU22950.1 - 1.4 9.0 11.2 0.47 10.5 1.3 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 OEU22950.1 - 1.4 9.2 13.0 1.4 9.2 0.4 2.9 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) DHR10 PF18595.1 OEU22950.1 - 1.6 8.8 11.1 9.4 6.3 0.7 3.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain PspA_IM30 PF04012.12 OEU22950.1 - 5.9 6.4 16.5 0.11 12.1 0.9 2.6 2 1 1 3 3 3 0 PspA/IM30 family DUF4407 PF14362.6 OEU22950.1 - 6.9 5.9 16.3 0.07 12.5 6.9 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Dirigent PF03018.14 OEU22955.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Dirigent-like protein Dirigent PF03018.14 OEU22956.1 - 0.00085 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Dirigent-like protein AOC_like PF18678.1 OEU22956.1 - 0.096 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Chalcone_3 PF16036.5 OEU22957.1 - 8.7e-13 48.7 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone_2 PF16035.5 OEU22957.1 - 0.00052 19.9 0.5 0.89 9.3 0.6 2.6 2 1 1 3 3 3 2 Chalcone isomerase like Chalcone PF02431.15 OEU22957.1 - 0.0011 18.4 0.0 0.082 12.3 0.0 2.6 1 1 0 1 1 1 1 Chalcone-flavanone isomerase malic PF00390.19 OEU22957.1 - 0.04 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain PseudoU_synth_1 PF01416.20 OEU22958.1 - 1.4e-23 83.4 0.0 1e-17 64.5 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase CRAL_TRIO PF00650.20 OEU22959.1 - 5.1e-12 45.8 1.0 1e-11 44.8 1.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain RR_TM4-6 PF06459.12 OEU22959.1 - 7.3 6.3 10.3 6 6.6 4.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Raffinose_syn PF05691.12 OEU22960.1 - 0.056 11.2 0.0 0.085 10.6 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DC_STAMP PF07782.13 OEU22961.1 - 0.22 11.3 2.1 0.33 10.7 2.1 1.2 1 0 0 1 1 1 0 DC-STAMP-like protein GILT PF03227.16 OEU22963.1 - 4.9e-28 97.5 1.8 8.3e-28 96.8 1.8 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) adh_short_C2 PF13561.6 OEU22965.1 - 2.5e-48 164.7 0.0 3.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OEU22965.1 - 7.7e-43 146.2 0.0 1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OEU22965.1 - 6e-12 45.8 0.1 8.5e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OEU22965.1 - 0.00077 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 OEU22965.1 - 0.0027 17.2 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3011 PF11218.8 OEU22965.1 - 0.024 14.6 0.3 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3011) RraA-like PF03737.15 OEU22965.1 - 0.047 13.9 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 Aldolase/RraA His_Phos_2 PF00328.22 OEU22966.1 - 7e-17 61.8 0.8 1.6e-14 54.1 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) FAM176 PF14851.6 OEU22966.1 - 0.087 12.5 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 FAM176 family LapA_dom PF06305.11 OEU22966.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain KIAA1430 PF13879.6 OEU22966.1 - 0.12 13.2 0.2 0.37 11.6 0.0 2.0 2 0 0 2 2 2 0 KIAA1430 homologue Beta-lactamase PF00144.24 OEU22968.1 - 8.3e-18 64.7 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase FA_desaturase PF00487.24 OEU22969.1 - 2.5e-09 37.4 6.5 3.6e-09 36.9 6.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase CENP-B_dimeris PF09026.10 OEU22970.1 - 0.018 15.4 2.8 0.018 15.4 2.8 2.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain BAG6 PF12057.8 OEU22970.1 - 0.075 12.7 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 BCL2-associated athanogene 6 DUF778 PF05608.12 OEU22970.1 - 0.17 12.3 1.1 0.36 11.2 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF445 PF04286.12 OEU22972.1 - 0.05 13.4 1.6 0.076 12.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CHCH PF06747.13 OEU22972.1 - 0.13 12.4 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 CHCH domain Med8 PF10232.9 OEU22972.1 - 0.2 11.2 1.6 0.26 10.8 1.6 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1002 PF06207.11 OEU22972.1 - 0.57 9.7 8.4 0.94 9.0 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) YpjP PF14005.6 OEU22972.1 - 1.1 9.4 3.1 1.9 8.5 3.1 1.4 1 0 0 1 1 1 0 YpjP-like protein Tubulin PF00091.25 OEU22972.1 - 1.5 9.0 7.6 3.4 7.8 0.1 2.9 2 1 1 3 3 3 0 Tubulin/FtsZ family, GTPase domain DUF3751 PF12571.8 OEU22973.1 - 0.005 16.9 0.1 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 Phage tail-collar fibre protein Acetyltransf_1 PF00583.25 OEU22974.1 - 6.6e-09 36.0 0.1 3.8e-08 33.6 0.0 2.2 2 1 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OEU22974.1 - 1.8e-07 31.5 0.1 4.4e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU22974.1 - 9.7e-06 25.5 0.4 0.0059 16.6 0.3 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OEU22974.1 - 0.0012 18.4 0.0 0.0028 17.1 0.0 1.8 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 OEU22974.1 - 0.0013 18.8 0.1 0.012 15.7 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OEU22974.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 OEU22974.1 - 0.0052 16.7 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase PAS_11 PF14598.6 OEU22974.1 - 0.012 15.8 3.1 0.025 14.7 3.1 1.5 1 0 0 1 1 1 0 PAS domain SRP68 PF16969.5 OEU22975.1 - 4.2e-66 224.1 33.8 1.2e-63 216.0 33.8 3.5 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 DNA_processg_A PF02481.15 OEU22975.1 - 0.015 14.6 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A TPR_12 PF13424.6 OEU22975.1 - 0.018 15.3 0.6 7 7.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MITF_TFEB_C_3_N PF15951.5 OEU22975.1 - 1.7 9.2 8.9 0.59 10.7 2.4 2.6 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus tRNA_bind PF01588.20 OEU22976.1 - 5.5e-22 77.7 0.0 9.5e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain DUF4820 PF16091.5 OEU22976.1 - 0.052 12.9 0.5 0.071 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PrcB_C PF14343.6 OEU22977.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 PrcB C-terminal Tn7_Tnp_TnsA_C PF08721.11 OEU22977.1 - 0.11 13.2 0.0 2.4 8.9 0.0 2.2 2 0 0 2 2 2 0 TnsA endonuclease C terminal Psb28 PF03912.14 OEU22978.1 - 2.7e-42 143.4 0.0 3e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Psb28 protein MotB_plug PF13677.6 OEU22979.1 - 0.054 13.1 0.2 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Bactofilin PF04519.13 OEU22980.1 - 1.8e-05 24.9 21.6 0.27 11.6 3.6 5.4 2 2 3 5 5 5 4 Polymer-forming cytoskeletal Methyltransf_11 PF08241.12 OEU22982.1 - 4.2e-05 24.1 0.0 0.0002 21.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OEU22982.1 - 0.05 13.4 0.1 0.33 10.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain BPL_LplA_LipB PF03099.19 OEU22983.1 - 8.9e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NDUFA12 PF05071.16 OEU22983.1 - 0.033 15.0 0.5 0.033 15.0 0.5 2.0 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4410 PF14366.6 OEU22983.1 - 0.12 12.3 0.3 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) CRISPR_assoc PF08798.11 OEU22983.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein DUF4834 PF16118.5 OEU22983.1 - 3.5 8.6 7.7 16 6.5 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FKBP_C PF00254.28 OEU22984.1 - 8.4e-14 51.7 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRM_1 PF00076.22 OEU22985.1 - 0.00011 21.9 0.0 0.033 14.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HrpB7 PF09486.10 OEU22985.1 - 3.3 8.1 12.9 1.7 9.0 0.4 3.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) RmlD_sub_bind PF04321.17 OEU22986.1 - 4.7e-11 42.3 0.0 1e-10 41.2 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OEU22986.1 - 9.2e-05 21.7 0.2 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OEU22986.1 - 0.00086 18.5 0.0 0.00098 18.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein HEPN_Toprim_N PF18871.1 OEU22988.1 - 0.12 12.3 0.3 0.27 11.1 0.3 1.5 1 1 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 RNA_pol_N PF01194.17 OEU22989.1 - 0.15 12.4 0.1 25 5.3 0.0 2.6 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit Voltage_CLC PF00654.20 OEU22990.1 - 8.9e-53 179.8 31.2 1.3e-51 175.9 31.2 2.0 1 1 0 1 1 1 1 Voltage gated chloride channel SET PF00856.28 OEU22991.1 - 1.5e-07 31.9 0.0 2.2e-06 28.1 0.0 3.2 1 1 0 1 1 1 1 SET domain IRK PF01007.20 OEU22993.1 - 5.6e-08 32.7 2.9 8.4e-08 32.1 2.9 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 OEU22993.1 - 2.9e-07 30.3 0.0 6.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain zf-C2H2_4 PF13894.6 OEU22993.1 - 0.00033 21.2 0.4 0.0016 19.1 0.4 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OEU22993.1 - 0.00061 20.1 2.2 0.00066 20.0 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OEU22993.1 - 0.012 15.6 0.4 0.028 14.4 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Dcc1 PF09724.9 OEU22993.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Sister chromatid cohesion protein Dcc1 Na_K-ATPase PF00287.18 OEU22993.1 - 0.2 10.8 0.8 0.31 10.1 0.8 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF4274 PF14096.6 OEU22994.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) Acetyltransf_9 PF13527.7 OEU22994.1 - 0.062 13.4 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_sheath_1N PF17481.2 OEU22995.1 - 0.024 15.1 0.0 0.029 14.9 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain DUF520 PF04461.13 OEU22995.1 - 0.14 12.2 1.7 0.54 10.4 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF520) FAM76 PF16046.5 OEU22996.1 - 0.00027 20.4 17.7 0.00027 20.4 17.7 4.6 2 1 1 4 4 4 2 FAM76 protein TMF_TATA_bd PF12325.8 OEU22996.1 - 0.00046 20.4 6.7 0.00046 20.4 6.7 8.2 4 2 4 9 9 9 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OEU22996.1 - 0.0071 16.3 12.7 0.0071 16.3 12.7 9.3 8 3 2 10 10 10 4 TATA element modulatory factor 1 DNA binding Glyoxalase PF00903.25 OEU22997.1 - 1.2e-09 38.5 0.1 2.2e-09 37.6 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OEU22997.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AP_endonuc_2 PF01261.24 OEU22997.1 - 0.045 13.2 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SH3_3 PF08239.11 OEU22998.1 - 0.1 12.9 2.1 1.1 9.7 0.1 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain PT PF04886.12 OEU22998.1 - 0.15 11.6 89.1 0.014 14.9 14.6 6.3 4 2 1 5 5 5 0 PT repeat AraC_binding PF02311.19 OEU22999.1 - 0.0059 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain DDHD PF02862.17 OEU22999.1 - 0.27 11.3 3.2 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 DDHD domain Vma12 PF11712.8 OEU22999.1 - 1.3 9.1 3.6 0.99 9.5 1.1 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase His_Phos_1 PF00300.22 OEU23000.1 - 8.6e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) EssA PF10661.9 OEU23000.1 - 0.042 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA TPR_1 PF00515.28 OEU23001.1 - 2.6e-26 90.3 19.1 6e-05 22.7 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 OEU23001.1 - 8.4e-21 72.4 13.0 4.6e-06 26.4 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU23001.1 - 1.8e-17 62.0 24.9 0.007 16.4 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 OEU23001.1 - 6.9e-15 54.5 6.5 1.5e-08 34.2 0.0 5.7 3 2 2 5 5 5 2 TPR repeat TPR_14 PF13428.6 OEU23001.1 - 1.7e-10 40.8 27.6 6.8e-05 23.4 0.0 8.4 7 2 3 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 OEU23001.1 - 2e-10 41.1 20.9 1.8e-05 25.3 0.2 6.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU23001.1 - 1.8e-09 38.0 12.8 0.018 15.5 0.0 6.1 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OEU23001.1 - 4.1e-09 35.8 21.5 0.22 11.6 1.7 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU23001.1 - 5.6e-07 29.7 17.4 0.013 15.7 1.6 4.7 2 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OEU23001.1 - 7.8e-07 29.3 30.9 0.73 10.2 0.0 6.7 4 2 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 OEU23001.1 - 2.5e-06 27.5 13.7 0.073 13.5 0.1 6.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OEU23001.1 - 1.8e-05 24.1 10.6 0.0033 16.7 1.3 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 OEU23001.1 - 0.00081 18.5 0.0 0.0023 17.0 0.0 1.6 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC8 PF04049.13 OEU23001.1 - 0.00085 19.4 0.9 0.0025 17.9 0.1 2.2 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.6 OEU23001.1 - 0.003 17.7 8.9 0.13 12.4 0.1 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat Sel1 PF08238.12 OEU23001.1 - 0.35 11.6 6.3 45 4.9 0.0 4.3 3 0 0 3 3 3 0 Sel1 repeat TPR_10 PF13374.6 OEU23001.1 - 0.49 10.3 18.5 11 6.0 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 OEU23001.1 - 1.2 9.5 8.9 1.8 9.0 0.9 3.6 2 1 2 4 4 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 OEU23001.1 - 3.2 8.6 0.0 3.2 8.6 0.0 8.2 9 1 0 9 9 8 0 Tetratricopeptide repeat zf-MYND PF01753.18 OEU23002.1 - 1.8e-09 37.5 15.5 1.8e-09 37.5 15.5 2.4 2 0 0 2 2 2 1 MYND finger zf_UBZ PF18439.1 OEU23002.1 - 0.16 11.6 3.7 4 7.1 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LRR_4 PF12799.7 OEU23003.1 - 0.11 12.9 7.4 5.8 7.5 0.2 4.6 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) MAPEG PF01124.18 OEU23004.1 - 3e-07 30.4 0.1 3.9e-07 30.0 0.1 1.3 1 1 0 1 1 1 1 MAPEG family DUF4033 PF13225.6 OEU23005.1 - 1.7e-35 120.8 0.5 2.5e-35 120.3 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Glyco_transf_49 PF13896.6 OEU23007.1 - 8.9e-07 28.6 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Terminase_6C PF17289.2 OEU23009.1 - 0.067 13.3 0.4 0.24 11.5 0.1 1.8 1 1 1 2 2 2 0 Terminase RNaseH-like domain BRF1 PF07741.13 OEU23009.1 - 0.12 12.7 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF643 PF04867.12 OEU23009.1 - 0.23 12.1 2.9 0.69 10.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF643) RVT_3 PF13456.6 OEU23010.1 - 8.2e-10 38.6 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 OEU23010.1 - 4.8e-07 30.0 0.0 7.1e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 RNase H Sigma_reg_C PF13791.6 OEU23010.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.6 1 1 1 2 2 2 0 Sigma factor regulator C-terminal Ribosomal_L1 PF00687.21 OEU23011.1 - 2.3e-30 105.9 0.0 3.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3446 PF11928.8 OEU23011.1 - 0.25 11.7 13.6 0.54 10.6 13.6 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain Mucin PF01456.17 OEU23012.1 - 0.094 12.7 5.5 0.29 11.1 5.5 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein CrgA PF06781.12 OEU23012.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF4834 PF16118.5 OEU23012.1 - 0.55 11.2 10.5 20 6.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Shisa PF13908.6 OEU23012.1 - 1.2 9.4 5.4 2.5 8.3 5.4 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FA_desaturase PF00487.24 OEU23013.1 - 2e-21 77.0 17.8 5.6e-21 75.5 17.8 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Pyr_redox_2 PF07992.14 OEU23014.1 - 2.5e-45 155.0 4.1 6.6e-45 153.6 4.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OEU23014.1 - 6.5e-25 87.5 0.3 1.7e-24 86.2 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OEU23014.1 - 2.6e-16 59.9 1.9 3.5e-12 46.7 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OEU23014.1 - 3.5e-10 39.5 11.6 0.00098 18.3 0.0 4.1 3 1 1 4 4 4 3 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OEU23014.1 - 1.8e-07 30.7 0.2 0.02 14.2 0.2 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OEU23014.1 - 6e-07 28.9 0.2 4.5e-06 26.1 0.0 2.4 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 OEU23014.1 - 6.2e-07 29.1 1.5 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OEU23014.1 - 8.9e-07 29.1 5.7 0.00036 20.7 0.3 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OEU23014.1 - 1.6e-05 24.1 1.7 0.021 13.9 0.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OEU23014.1 - 2.7e-05 23.6 0.3 0.17 11.1 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OEU23014.1 - 8.2e-05 22.3 5.9 0.011 15.4 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OEU23014.1 - 0.00014 21.1 13.1 0.0029 16.7 0.4 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 OEU23014.1 - 0.00048 20.5 0.1 0.04 14.3 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.14 OEU23014.1 - 0.00051 18.9 1.9 0.0081 14.9 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OEU23014.1 - 0.0023 17.2 5.3 0.04 13.1 1.0 2.3 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.18 OEU23014.1 - 0.014 15.6 1.7 1.4 9.2 0.1 3.5 3 0 0 3 3 3 0 TrkA-N domain ThiF PF00899.21 OEU23014.1 - 0.022 14.1 0.1 0.075 12.4 0.1 1.9 2 0 0 2 2 2 0 ThiF family FMO-like PF00743.19 OEU23014.1 - 0.026 13.0 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DFP PF04127.15 OEU23014.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Deltameth_res PF16020.5 OEU23014.1 - 0.059 13.3 0.5 0.14 12.1 0.5 1.6 1 0 0 1 1 1 0 Deltamethrin resistance 3HCDH_N PF02737.18 OEU23014.1 - 0.059 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 OEU23014.1 - 0.075 11.9 3.5 0.098 11.5 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Methyltransf_12 PF08242.12 OEU23014.1 - 1.8 9.4 7.0 5.9 7.7 0.8 3.5 2 1 1 3 3 3 0 Methyltransferase domain Lung_7-TM_R PF06814.13 OEU23015.1 - 0.0032 16.8 0.5 0.0069 15.7 0.5 1.5 1 0 0 1 1 1 1 Lung seven transmembrane receptor FUSC-like PF12805.7 OEU23015.1 - 0.64 9.0 3.5 2.2 7.3 3.9 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Methyltransf_16 PF10294.9 OEU23016.1 - 2.1e-20 73.2 1.7 5.8e-20 71.7 1.7 1.7 1 1 0 1 1 1 1 Lysine methyltransferase RFX5_N PF18326.1 OEU23016.1 - 0.04 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 RFX5 N-terminal domain Methyltransf_12 PF08242.12 OEU23016.1 - 0.17 12.6 1.9 2.7 8.8 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain DUF3069 PF11269.8 OEU23017.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) IU_nuc_hydro PF01156.19 OEU23018.1 - 7e-21 75.1 1.1 1.6e-20 73.9 1.1 1.6 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CheY-binding PF09078.11 OEU23018.1 - 0.25 11.5 1.5 0.67 10.1 1.5 1.6 1 0 0 1 1 1 0 CheY binding DUF4983 PF16356.5 OEU23018.1 - 0.62 10.9 4.6 16 6.4 0.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4983) TFIIE-A_C PF11521.8 OEU23018.1 - 3.9 7.9 0.0 3.9 7.9 0.0 3.6 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha FAD_binding_3 PF01494.19 OEU23019.1 - 5.5e-58 196.9 0.0 1.7e-57 195.3 0.0 1.8 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OEU23019.1 - 4e-06 26.2 0.1 5.2e-05 22.5 0.1 2.3 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 OEU23019.1 - 9.9e-06 25.0 0.1 3.8e-05 23.1 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OEU23019.1 - 2e-05 24.0 0.1 3.7e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OEU23019.1 - 0.00016 20.5 0.0 0.00039 19.3 0.0 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OEU23019.1 - 0.0002 20.8 0.1 0.00039 19.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OEU23019.1 - 0.00034 19.9 0.2 0.0014 17.9 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU23019.1 - 0.0017 18.9 0.1 0.0045 17.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU23019.1 - 0.002 18.3 0.1 0.0063 16.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OEU23019.1 - 0.0026 17.4 0.1 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OEU23019.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OEU23019.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 OEU23019.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 OEU23019.1 - 0.041 14.4 0.1 0.24 11.9 0.0 2.3 3 0 0 3 3 3 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 OEU23019.1 - 0.082 11.9 0.1 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Staph_opine_DH PF10100.9 OEU23019.1 - 0.12 11.0 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 Staphylopine dehydrogenase HSP70 PF00012.20 OEU23020.1 - 0.034 12.3 8.9 0.052 11.7 8.9 1.2 1 0 0 1 1 1 0 Hsp70 protein PI3K_1B_p101 PF10486.9 OEU23020.1 - 0.23 9.2 10.0 0.35 8.6 10.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 OEU23020.1 - 0.35 9.1 14.5 0.58 8.4 14.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OEU23020.1 - 1.5 6.8 13.6 2.2 6.2 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi DivIC PF04977.15 OEU23022.1 - 0.2 11.5 3.0 4.7 7.1 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator TFIIA PF03153.13 OEU23023.1 - 0.0057 16.7 8.1 0.0057 16.7 8.1 3.0 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4199 PF13858.6 OEU23023.1 - 0.12 12.7 0.6 0.29 11.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) zf-RING_2 PF13639.6 OEU23025.1 - 0.0011 19.3 11.9 0.0085 16.4 11.9 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU23025.1 - 0.0033 17.1 7.8 0.029 14.1 7.8 2.5 1 1 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OEU23025.1 - 0.019 15.0 2.3 0.039 14.0 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3801 PF12687.7 OEU23025.1 - 0.026 14.6 3.0 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) PIH1 PF08190.12 OEU23025.1 - 0.1 12.0 0.1 0.1 12.0 0.1 2.2 3 0 0 3 3 3 0 PIH1 N-terminal domain Hydin_ADK PF17213.3 OEU23025.1 - 2.5 8.3 8.6 0.4 10.9 0.2 2.4 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain 2OG-FeII_Oxy PF03171.20 OEU23026.1 - 1.9e-05 25.1 0.1 1.9e-05 25.1 0.1 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GOLD_2 PF13897.6 OEU23027.1 - 0.014 15.9 0.3 0.57 10.7 0.1 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Helicase_C PF00271.31 OEU23028.1 - 1.5e-20 73.6 0.0 2.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OEU23028.1 - 6e-18 65.2 0.1 7.3e-15 55.2 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 OEU23028.1 - 0.002 18.2 0.0 0.0067 16.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OEU23028.1 - 0.018 15.3 0.0 0.051 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OEU23028.1 - 0.02 15.3 0.0 0.082 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 OEU23028.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding SprA-related PF12118.8 OEU23029.1 - 0.0037 16.5 11.4 0.0054 15.9 11.4 1.2 1 0 0 1 1 1 1 SprA-related family CDC45 PF02724.14 OEU23029.1 - 0.093 11.0 14.7 0.12 10.6 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 OEU23029.1 - 2 6.5 12.1 2.7 6.0 12.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 OEU23029.1 - 7.9 7.0 7.5 12 6.4 7.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 OEU23029.1 - 8.2 5.1 12.7 12 4.5 12.7 1.3 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 OEU23029.1 - 9.8 4.0 12.3 13 3.5 12.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Acetyltransf_1 PF00583.25 OEU23031.1 - 0.018 15.2 0.0 0.06 13.6 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OEU23031.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aminotran_1_2 PF00155.21 OEU23032.1 - 1e-60 205.9 0.0 1.2e-60 205.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OEU23032.1 - 1.7e-05 23.6 0.0 2.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SpoVAE PF14097.6 OEU23032.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Aminotran_5 PF00266.19 OEU23032.1 - 0.076 12.0 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Met_gamma_lyase PF06838.11 OEU23032.1 - 0.11 11.0 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase Plasmodium_Vir PF05795.11 OEU23035.1 - 0.0052 16.2 0.9 0.0066 15.9 0.9 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein HupE_UreJ_2 PF13795.6 OEU23035.1 - 0.047 13.4 2.0 0.39 10.4 1.4 2.2 2 0 0 2 2 2 0 HupE / UreJ protein YrhK PF14145.6 OEU23036.1 - 0.027 14.3 12.6 1.1 9.2 0.5 3.7 3 1 0 3 3 3 0 YrhK-like protein Zw10 PF06248.13 OEU23037.1 - 7.1e-24 84.3 7.2 4.5e-23 81.6 0.2 3.1 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 S-antigen PF05756.11 OEU23037.1 - 0.19 12.1 0.6 0.64 10.4 0.6 1.9 1 0 0 1 1 1 0 S-antigen protein VWA PF00092.28 OEU23037.1 - 0.2 11.9 2.0 0.22 11.7 0.6 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain PDZ PF00595.24 OEU23038.1 - 2.8e-06 27.6 0.0 6.2e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OEU23038.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 OEU23038.1 - 0.00016 22.0 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU23038.1 - 0.00052 20.3 0.0 0.00071 19.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 OEU23038.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain ADH_zinc_N PF00107.26 OEU23039.1 - 9.1e-18 64.5 0.8 1.7e-17 63.6 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OEU23039.1 - 4.3e-11 44.0 0.1 2.3e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OEU23039.1 - 0.00021 21.1 0.0 0.0019 18.0 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 OEU23039.1 - 0.0029 17.1 0.2 0.0046 16.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase PALP PF00291.25 OEU23039.1 - 0.0056 16.1 0.6 0.017 14.6 0.1 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.8 OEU23039.1 - 0.013 15.3 0.1 0.038 13.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 OEU23039.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Copper-bind PF00127.20 OEU23040.1 - 0.086 13.3 0.3 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Phage_base_V PF04717.12 OEU23040.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Dishevelled PF02377.15 OEU23040.1 - 1.1 9.7 6.7 0.066 13.7 0.5 2.1 2 1 1 3 3 3 0 Dishevelled specific domain Methyltransf_32 PF13679.6 OEU23041.1 - 3.5e-10 40.1 0.4 6.7e-10 39.2 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-C2H2_jaz PF12171.8 OEU23041.1 - 0.00037 20.7 3.1 0.00073 19.8 3.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding MTS PF05175.14 OEU23041.1 - 0.0043 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OEU23041.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain zf-met PF12874.7 OEU23041.1 - 0.0098 16.3 3.7 0.026 14.9 3.7 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Methyltransf_8 PF05148.15 OEU23041.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 OEU23041.1 - 0.042 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 OEU23041.1 - 0.042 14.5 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 OEU23041.1 - 0.051 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase zf-U1 PF06220.12 OEU23041.1 - 0.052 13.3 1.7 0.13 12.1 1.7 1.7 1 0 0 1 1 1 0 U1 zinc finger Methyltransf_12 PF08242.12 OEU23041.1 - 0.14 12.9 0.1 0.56 11.0 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain PT PF04886.12 OEU23042.1 - 3.4e-11 42.5 27.8 6.8e-07 28.7 18.2 2.8 2 1 0 2 2 2 1 PT repeat SID-1_RNA_chan PF13965.6 OEU23043.1 - 0.069 11.6 1.6 0.087 11.2 1.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2206 PF09971.9 OEU23043.1 - 0.1 11.3 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) SR-25 PF10500.9 OEU23043.1 - 6.9 6.2 15.5 0.4 10.2 1.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NCBP3 PF10309.9 OEU23044.1 - 2.9e-09 36.6 0.2 7.6e-09 35.3 0.2 1.8 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Methyltransf_FA PF12248.8 OEU23044.1 - 0.00044 20.5 5.8 0.00061 20.1 2.2 2.9 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase RNA_bind PF08675.11 OEU23044.1 - 0.00057 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.11 OEU23044.1 - 0.0022 18.0 0.0 0.027 14.5 0.0 2.9 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 OEU23044.1 - 0.012 15.4 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2Fe-2S_thioredx PF01257.19 OEU23045.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF1997 PF09366.10 OEU23046.1 - 1.4e-19 70.7 0.0 2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) Peroxidase_2 PF01328.17 OEU23046.1 - 0.018 15.6 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Peroxidase, family 2 Vps8 PF12816.7 OEU23047.1 - 1.9e-48 164.6 1.7 3.8e-46 157.1 0.4 3.5 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OEU23047.1 - 3.5e-09 36.7 2.4 7.7e-07 29.1 0.7 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS rhaM PF05336.13 OEU23047.1 - 0.16 12.0 0.5 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 L-rhamnose mutarotase 2OG-FeII_Oxy_3 PF13640.6 OEU23049.1 - 2e-16 60.7 0.1 4.1e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU23049.1 - 0.0016 18.9 0.1 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Rap1a PF18602.1 OEU23049.1 - 0.024 15.0 0.1 0.047 14.0 0.1 1.4 1 0 0 1 1 1 0 Rap1a immunity proteins WLM PF08325.10 OEU23052.1 - 2.1e-16 60.5 0.8 2.1e-16 60.5 0.8 3.6 3 1 0 3 3 3 1 WLM domain Med3 PF11593.8 OEU23052.1 - 0.066 12.4 12.9 0.12 11.5 12.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 OEU23052.1 - 0.072 13.1 17.9 0.29 11.1 8.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 OEU23052.1 - 0.1 13.3 8.9 0.21 12.2 8.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 OEU23052.1 - 0.16 10.6 5.8 0.21 10.2 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 OEU23052.1 - 2.1 6.4 9.8 3 5.9 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 OEU23052.1 - 2.3 7.4 11.1 0.05 12.8 3.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter SprA-related PF12118.8 OEU23052.1 - 2.4 7.2 19.9 0.15 11.2 14.3 1.7 2 0 0 2 2 2 0 SprA-related family Hydin_ADK PF17213.3 OEU23052.1 - 2.5 8.4 15.7 1.9 8.7 12.2 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SR-25 PF10500.9 OEU23052.1 - 2.5 7.6 24.9 0.54 9.8 15.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 OEU23052.1 - 3.2 4.7 9.4 5 4.1 9.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Amidohydro_2 PF04909.14 OEU23054.1 - 0.0034 17.2 0.1 0.0038 17.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF1860 PF08949.10 OEU23055.1 - 0.0072 16.1 0.4 0.0097 15.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1860) DUF3073 PF11273.8 OEU23055.1 - 0.74 10.6 4.4 1.4 9.7 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) FAA_hydrolase PF01557.18 OEU23056.1 - 1.6e-41 142.3 0.0 3.5e-41 141.3 0.0 1.5 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SIS_2 PF13580.6 OEU23056.1 - 0.091 12.8 0.4 2.8 7.9 0.0 2.5 3 0 0 3 3 3 0 SIS domain DUF3972 PF13118.6 OEU23057.1 - 0.053 14.0 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) MIP PF00230.20 OEU23058.1 - 2.6e-17 63.3 7.7 5.8e-17 62.2 7.7 1.5 1 1 0 1 1 1 1 Major intrinsic protein JAB PF01398.21 OEU23059.1 - 3.5e-13 49.6 0.0 8.8e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ctr PF04145.15 OEU23061.1 - 4e-07 30.8 11.7 4e-07 30.8 11.7 5.3 4 3 1 5 5 5 2 Ctr copper transporter family Exo_endo_phos PF03372.23 OEU23062.1 - 3.4e-06 26.7 0.0 0.0001 21.9 0.0 3.0 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Aminotran_1_2 PF00155.21 OEU23063.1 - 3.2e-36 125.3 0.0 4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OEU23063.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 OEU23063.1 - 0.13 10.9 0.0 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-III p450 PF00067.22 OEU23064.1 - 8.3e-45 153.4 0.0 1e-44 153.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OEU23065.1 - 8e-08 31.5 0.0 8.7e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 OEU23066.1 - 4e-46 157.9 7.2 2.8e-42 145.2 1.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OEU23066.1 - 1.5e-35 122.7 0.6 2.9e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OEU23066.1 - 1.6e-06 27.7 2.4 0.00044 19.8 0.1 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 OEU23066.1 - 0.0013 18.5 0.1 0.0032 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OEU23066.1 - 0.0029 17.3 0.3 0.0068 16.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OEU23066.1 - 0.0033 17.2 0.0 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 OEU23066.1 - 0.0034 17.1 0.6 0.012 15.3 0.6 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU23066.1 - 0.009 16.4 0.4 0.038 14.4 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OEU23066.1 - 0.01 15.7 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 OEU23066.1 - 0.022 15.0 0.4 0.22 11.8 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 OEU23066.1 - 0.036 13.4 0.2 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.6 OEU23066.1 - 0.045 13.6 0.3 0.61 9.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OEU23066.1 - 0.062 13.6 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OEU23066.1 - 0.073 13.2 0.4 0.19 11.8 0.4 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Reticulon PF02453.17 OEU23066.1 - 0.079 12.9 4.2 0.36 10.8 0.3 2.5 2 0 0 2 2 2 0 Reticulon ABC_ATPase PF09818.9 OEU23066.1 - 0.24 10.2 2.7 2.1 7.1 0.1 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SAP PF02037.27 OEU23067.1 - 2e-10 40.2 0.8 2e-10 40.2 0.8 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 OEU23067.1 - 0.016 14.9 0.2 0.044 13.5 0.2 1.8 1 0 0 1 1 1 0 HeH/LEM domain GPI2 PF06432.11 OEU23068.1 - 0.034 13.6 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4592 PF15262.6 OEU23069.1 - 0.079 13.6 0.7 0.12 13.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) DUF1635 PF07795.11 OEU23069.1 - 0.09 12.6 0.8 0.11 12.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Fungus-induced PF10917.8 OEU23069.1 - 0.19 12.0 8.2 0.83 10.0 2.9 2.3 2 0 0 2 2 2 0 Fungus-induced protein DUF4679 PF15728.5 OEU23069.1 - 0.23 10.5 2.7 0.27 10.2 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) BUD22 PF09073.10 OEU23069.1 - 2.4 7.4 8.9 3 7.1 8.9 1.0 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 OEU23069.1 - 3.2 6.2 5.3 3.3 6.2 5.3 1.0 1 0 0 1 1 1 0 Macoilin family MOSC PF03473.17 OEU23070.1 - 9.8e-29 100.0 0.0 7.6e-28 97.1 0.0 2.0 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 OEU23070.1 - 3.4e-11 43.1 0.0 1.7e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain ZapB PF06005.12 OEU23071.1 - 0.0086 16.5 0.2 0.0086 16.5 0.2 6.7 8 0 0 8 8 8 3 Cell division protein ZapB PDZ PF00595.24 OEU23071.1 - 0.032 14.6 0.0 0.17 12.2 0.0 2.3 1 0 0 1 1 1 0 PDZ domain DUF1604 PF07713.13 OEU23072.1 - 0.16 11.8 1.6 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) POM121 PF15229.6 OEU23072.1 - 0.5 10.0 7.2 0.84 9.2 7.2 1.4 1 0 0 1 1 1 0 POM121 family Peptidase_M50 PF02163.22 OEU23073.1 - 7.1e-54 182.7 0.0 8.3e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 OEU23073.1 - 0.00079 19.7 0.2 0.0025 18.1 0.2 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OEU23073.1 - 0.074 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 PDZ domain IMUP PF15761.5 OEU23075.1 - 2.4 8.9 8.2 0.22 12.2 0.9 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Ig_5 PF16681.5 OEU23076.1 - 0.025 15.0 0.1 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LBR_tudor PF09465.10 OEU23077.1 - 0.0071 16.1 0.4 0.019 14.8 0.4 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain rve PF00665.26 OEU23077.1 - 0.089 13.0 0.0 0.32 11.2 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain 2-oxoacid_dh PF00198.23 OEU23078.1 - 7.7e-64 215.3 0.0 1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OEU23078.1 - 6.1e-17 61.2 0.0 1.3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OEU23078.1 - 9.1e-15 54.7 0.0 2.6e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OEU23078.1 - 0.0029 17.4 0.1 2.2 8.2 0.1 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like PYNP_C PF07831.13 OEU23078.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain GHMP_kinases_C PF08544.13 OEU23078.1 - 0.12 12.8 0.2 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal HlyD_3 PF13437.6 OEU23078.1 - 0.15 12.7 0.0 2.1 9.1 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Bacteriocin_IIc PF10439.9 OEU23078.1 - 0.33 11.1 2.3 0.63 10.2 2.3 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Sulfotransfer_3 PF13469.6 OEU23079.1 - 0.00034 21.1 0.2 0.98 9.8 0.0 3.6 2 2 1 3 3 3 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OEU23079.1 - 0.00042 20.3 5.2 0.00042 20.3 5.2 3.2 3 1 0 3 3 3 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OEU23079.1 - 0.00098 18.7 0.5 0.039 13.4 0.0 3.1 3 0 0 3 3 3 1 Sulfotransferase domain TPR_12 PF13424.6 OEU23081.1 - 2e-07 31.2 4.3 0.0067 16.7 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OEU23081.1 - 4.2e-07 29.6 3.0 0.025 14.7 0.9 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU23081.1 - 0.00023 20.9 0.7 0.84 9.6 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU23081.1 - 0.00041 20.9 6.2 1.5 9.9 1.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OEU23081.1 - 0.0011 18.6 1.0 1.7 8.4 0.0 3.6 3 1 1 4 4 4 1 TPR repeat SNAP PF14938.6 OEU23081.1 - 0.0016 17.9 1.0 0.0025 17.3 0.1 1.7 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 OEU23081.1 - 0.01 16.0 2.1 6.1 7.3 0.5 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU23081.1 - 0.012 15.6 2.6 6 7.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OEU23081.1 - 0.044 14.4 2.2 1.5 9.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OEU23081.1 - 0.047 14.3 2.5 6.9 7.4 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU23081.1 - 3.2 7.7 5.4 19 5.3 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OEU23082.1 - 1.9e-14 53.5 0.4 2.2e-14 53.4 0.4 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU23082.1 - 5.2e-06 26.6 0.6 6.1e-06 26.4 0.6 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU23082.1 - 0.00015 21.6 0.1 0.00018 21.3 0.1 1.2 1 0 0 1 1 1 1 Myb DNA-binding like FemAB PF02388.16 OEU23082.1 - 0.036 12.9 0.0 0.038 12.9 0.0 1.0 1 0 0 1 1 1 0 FemAB family PhyH PF05721.13 OEU23083.1 - 0.00046 20.5 0.0 0.0079 16.5 0.0 2.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TMEM189_B_dmain PF10520.9 OEU23084.1 - 4.7e-54 183.1 0.2 5.7e-54 182.8 0.2 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 OEU23084.1 - 0.00021 21.6 0.1 0.00032 21.1 0.1 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily TMEM173 PF15009.6 OEU23084.1 - 0.023 13.9 0.7 0.19 10.8 0.1 1.9 1 1 1 2 2 2 0 Transmembrane protein 173 FKBP_C PF00254.28 OEU23086.1 - 6.1e-28 97.0 0.0 6.6e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 OEU23087.1 - 3e-26 91.6 0.1 5.2e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 OEU23087.1 - 2.5e-07 31.0 3.8 2.5e-07 31.0 3.8 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OEU23087.1 - 9.4e-07 28.3 5.4 0.0025 17.6 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OEU23087.1 - 3.5e-06 26.2 10.1 0.011 15.3 2.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OEU23087.1 - 7.9e-05 22.0 8.7 0.014 14.9 1.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OEU23087.1 - 0.027 14.3 7.1 0.48 10.3 0.4 2.4 2 0 0 2 2 2 0 EF-hand domain pair Carn_acyltransf PF00755.20 OEU23088.1 - 8.6e-171 569.5 0.0 9.7e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MscS_porin PF12795.7 OEU23088.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SLH PF00395.20 OEU23088.1 - 0.16 12.0 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 S-layer homology domain Pkinase PF00069.25 OEU23089.1 - 6.2e-73 245.4 0.0 7.7e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU23089.1 - 9.7e-33 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OEU23089.1 - 6e-05 22.5 0.0 0.00033 20.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OEU23089.1 - 0.00032 20.7 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OEU23089.1 - 0.001 18.1 0.0 0.0034 16.4 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OEU23089.1 - 0.0012 18.2 0.1 0.0027 17.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CreD PF06123.12 OEU23090.1 - 0.035 12.9 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 Inner membrane protein CreD Phage_holin_3_6 PF07332.11 OEU23090.1 - 0.21 11.7 0.1 0.34 11.0 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Zn-C2H2_12 PF18112.1 OEU23091.1 - 0.0052 17.2 0.3 0.018 15.5 0.3 2.0 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain DUF1736 PF08409.11 OEU23092.1 - 0.003 17.5 2.7 0.045 13.7 0.0 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF1736) RNase_H PF00075.24 OEU23093.1 - 9.2e-05 22.7 0.1 0.0032 17.6 0.0 2.8 3 0 0 3 3 3 1 RNase H zf-RVT PF13966.6 OEU23093.1 - 0.0083 16.8 1.3 0.0083 16.8 1.3 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase APG5 PF04106.12 OEU23093.1 - 1.5 8.4 5.8 2.1 7.9 3.7 2.1 1 1 1 2 2 2 0 Autophagy protein Apg5 Transketolase_C PF02780.20 OEU23094.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain RVT_1 PF00078.27 OEU23095.1 - 4.2e-05 23.2 0.0 9.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OEU23095.1 - 0.0049 16.4 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LBR_tudor PF09465.10 OEU23095.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Cytochrom_NNT PF03264.14 OEU23095.1 - 3.2 7.4 5.6 1.7 8.3 2.2 2.3 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Topoisom_I_N PF02919.15 OEU23096.1 - 6.5e-05 22.5 1.9 8.1e-05 22.2 1.7 1.3 1 1 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Mei5_like PF17021.5 OEU23096.1 - 0.016 15.3 0.1 0.016 15.3 0.1 2.3 1 1 1 2 2 2 0 Putative double-strand recombination repair-like Cnl2_NKP2 PF09447.10 OEU23096.1 - 0.021 15.0 1.5 1.3 9.2 0.5 2.4 1 1 1 2 2 2 0 Cnl2/NKP2 family protein DUF1043 PF06295.12 OEU23096.1 - 0.036 14.1 1.9 0.041 13.9 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) GT-D PF08759.11 OEU23096.1 - 0.14 11.8 3.1 0.26 11.0 2.7 1.6 1 1 0 1 1 1 0 Glycosyltransferase GT-D fold Cyclin_N PF00134.23 OEU23097.1 - 3.1e-06 27.0 0.2 8e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF775 PF05603.12 OEU23097.1 - 2.3 7.7 7.9 4.1 6.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) zf-FCS PF06467.14 OEU23099.1 - 0.0067 16.3 9.0 0.016 15.1 0.5 3.1 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif Methyltransf_2 PF00891.18 OEU23099.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF4690 PF15756.5 OEU23100.1 - 0.0073 16.9 0.3 0.019 15.6 0.0 1.8 2 0 0 2 2 2 1 Small Novel Rich in Cartilage MgrB PF13998.6 OEU23100.1 - 1.6 8.7 3.5 2 8.4 0.1 2.7 2 1 0 2 2 2 0 MgrB protein Peptidase_C14 PF00656.22 OEU23102.1 - 3.1e-21 76.5 0.5 8.3e-21 75.1 0.0 1.9 2 1 0 2 2 2 1 Caspase domain Mitofilin PF09731.9 OEU23102.1 - 0.00018 20.6 21.1 0.018 13.9 14.3 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Trp_oprn_chp PF09534.10 OEU23102.1 - 0.049 13.4 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM51 PF15345.6 OEU23102.1 - 0.14 11.9 12.3 0.51 10.1 4.4 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 BUD22 PF09073.10 OEU23102.1 - 0.49 9.7 43.8 0.46 9.8 1.5 2.1 2 0 0 2 2 2 0 BUD22 DUF2448 PF10476.9 OEU23102.1 - 4.1 7.2 5.5 0.73 9.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) R_equi_Vir PF05526.11 OEU23102.1 - 6.5 6.6 4.9 1.1 9.1 0.3 2.0 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein SURF2 PF05477.11 OEU23102.1 - 7.3 6.2 32.8 8.1 6.1 1.1 2.2 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Oxidored_molyb PF00174.19 OEU23103.1 - 2.1e-50 170.7 0.1 7.2e-50 169.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OEU23103.1 - 6e-24 84.6 0.5 2.1e-23 82.9 0.7 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 OEU23103.1 - 3.5e-11 43.1 0.0 8.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acid_PPase PF12689.7 OEU23105.1 - 5.2e-33 114.3 0.0 6.2e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase tRNA-synt_2c PF01411.19 OEU23105.1 - 0.15 10.6 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Ribosomal_L10 PF00466.20 OEU23107.1 - 7.7e-23 80.5 0.0 1.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 OEU23107.1 - 3e-19 68.8 0.3 5.8e-19 67.9 0.3 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P HpcH_HpaI PF03328.14 OEU23108.1 - 1.6e-37 128.8 0.4 8.9e-32 110.0 0.2 2.1 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OEU23108.1 - 8.6e-15 54.7 0.1 3.8e-07 29.6 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 OEU23108.1 - 0.023 13.6 0.2 0.03 13.2 0.2 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain HA PF03457.14 OEU23109.1 - 9.8e-29 99.5 2.5 8.4e-18 64.5 0.4 2.1 2 0 0 2 2 2 2 Helicase associated domain DUF3047 PF11249.8 OEU23109.1 - 0.019 14.4 0.4 0.024 14.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) DUF4817 PF16087.5 OEU23109.1 - 0.035 13.9 0.2 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) LRR_6 PF13516.6 OEU23110.1 - 5.1e-10 38.6 11.8 0.0015 18.4 0.0 6.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 OEU23110.1 - 0.00014 22.2 7.1 0.094 13.2 0.3 5.2 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU23110.1 - 0.0026 17.5 4.4 8.9 6.2 0.0 4.9 4 0 0 4 4 4 1 Leucine rich repeat LRR_5 PF13306.6 OEU23110.1 - 0.096 12.6 1.3 12 5.8 0.0 3.3 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OEU23110.1 - 2.7 8.9 14.0 17 6.4 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat Glyco_transf_7C PF02709.14 OEU23111.1 - 3.7e-20 71.4 0.2 7.8e-20 70.3 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 OEU23111.1 - 6.4e-18 64.7 0.8 9.3e-18 64.2 0.8 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 NYN PF01936.18 OEU23111.1 - 0.12 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 NYN domain GTP_EFTU PF00009.27 OEU23112.1 - 1.4e-46 158.5 0.9 2.2e-46 157.8 0.9 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OEU23112.1 - 1.1e-14 54.2 0.0 2.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 OEU23112.1 - 5.4e-07 29.7 0.1 5.2e-06 26.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OEU23112.1 - 7.6e-07 29.4 0.2 7.1e-06 26.3 0.2 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 OEU23112.1 - 0.019 14.4 0.7 0.81 9.1 0.2 2.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OEU23112.1 - 0.027 14.0 0.5 0.6 9.6 0.2 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B EFG_II PF14492.6 OEU23112.1 - 0.099 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II Septin PF00735.18 OEU23112.1 - 0.1 11.8 0.3 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 Septin Colicin_Pyocin PF01320.18 OEU23113.1 - 0.093 12.9 0.0 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein ArfGap PF01412.18 OEU23114.1 - 6.8e-29 100.3 0.1 7.3e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TackOD1 PF18551.1 OEU23114.1 - 0.004 16.9 0.1 0.0054 16.4 0.1 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Cwf_Cwc_15 PF04889.12 OEU23116.1 - 0.31 10.8 19.2 0.41 10.3 19.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAML PF14963.6 OEU23116.1 - 0.45 10.6 6.1 0.12 12.5 3.2 1.5 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand RR_TM4-6 PF06459.12 OEU23116.1 - 0.79 9.5 9.9 0.99 9.2 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Menin PF05053.13 OEU23116.1 - 1.2 7.4 9.1 1.4 7.2 9.1 1.0 1 0 0 1 1 1 0 Menin Dsh_C PF12316.8 OEU23116.1 - 5.7 7.3 7.5 6.9 7.0 7.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Aminotran_1_2 PF00155.21 OEU23117.1 - 6.9e-31 107.7 0.0 8.4e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OEU23117.1 - 6.5e-06 25.3 0.1 9.1e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OEU23117.1 - 7.3e-05 21.5 0.0 9.7e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OEU23117.1 - 0.0002 20.8 0.0 0.00023 20.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 OEU23117.1 - 0.0075 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Allinase Aminotran_3 PF00202.21 OEU23117.1 - 0.0075 15.0 0.4 0.013 14.2 0.4 1.4 1 1 0 1 1 1 1 Aminotransferase class-III PALP PF00291.25 OEU23117.1 - 0.032 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme XkdW PF09636.10 OEU23118.1 - 0.061 13.4 2.0 0.12 12.4 0.6 2.3 2 0 0 2 2 2 0 XkdW protein COG5 PF10392.9 OEU23118.1 - 0.089 13.0 0.2 0.089 13.0 0.2 4.4 4 1 2 6 6 6 0 Golgi transport complex subunit 5 Mito_carr PF00153.27 OEU23120.1 - 1.6e-60 201.1 0.1 2.2e-19 69.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RL11D PF11088.8 OEU23121.1 - 0.057 13.7 3.7 0.13 12.5 3.7 1.6 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 HRDC PF00570.23 OEU23122.1 - 7.1e-10 38.7 0.0 2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain DoxX PF07681.12 OEU23124.1 - 1.3e-15 57.8 6.5 1.3e-15 57.8 6.5 1.6 2 0 0 2 2 2 1 DoxX Dynamin_N PF00350.23 OEU23125.1 - 6.1e-15 55.7 1.2 1.1e-14 54.9 1.2 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OEU23125.1 - 1.2e-11 44.7 2.8 1.7e-11 44.2 0.8 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OEU23125.1 - 1.3e-09 37.9 2.3 7.3e-09 35.5 2.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 OEU23125.1 - 2.2e-05 24.7 2.4 0.038 14.2 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU23125.1 - 6.2e-05 22.5 0.1 0.038 13.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 OEU23125.1 - 0.00041 20.0 0.6 1 8.9 0.0 2.6 2 0 0 2 2 2 2 Ras family FeoB_N PF02421.18 OEU23125.1 - 0.012 15.1 1.6 0.75 9.3 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B BRCA-2_helical PF09169.10 OEU23125.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 BRCA2, helical RsgA_GTPase PF03193.16 OEU23125.1 - 0.017 15.0 0.1 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 OEU23125.1 - 0.14 11.4 3.2 0.87 8.9 0.2 2.4 2 0 0 2 2 2 0 AIG1 family NOG1 PF06858.14 OEU23125.1 - 0.19 11.6 1.8 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) NAD_binding_2 PF03446.15 OEU23126.1 - 1.3e-06 28.6 0.0 2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 OEU23126.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 OEU23126.1 - 0.00036 20.6 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OEU23126.1 - 0.0041 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OEU23126.1 - 0.005 17.4 0.0 0.0096 16.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OEU23126.1 - 0.0057 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OEU23126.1 - 0.0088 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TFIIE_beta PF02186.15 OEU23128.1 - 0.085 13.1 4.7 2 8.8 0.4 4.0 3 0 0 3 3 3 0 TFIIE beta subunit core domain CutA1 PF03091.15 OEU23128.1 - 0.18 11.7 4.6 33 4.4 0.0 4.9 5 0 0 5 5 5 0 CutA1 divalent ion tolerance protein zf-MYND PF01753.18 OEU23129.1 - 5.4e-06 26.4 15.6 9.5e-06 25.6 15.6 1.4 1 0 0 1 1 1 1 MYND finger FUSC PF04632.12 OEU23131.1 - 3.2e-07 29.3 4.0 3.6e-07 29.2 2.3 1.9 2 0 0 2 2 2 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 OEU23131.1 - 2.1e-06 27.9 6.3 2.1e-06 27.9 6.3 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like IRK PF01007.20 OEU23131.1 - 0.036 13.9 1.7 0.095 12.5 1.7 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Cytochrom_B562 PF07361.11 OEU23131.1 - 0.097 13.3 0.0 0.71 10.6 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b562 Glutaredoxin PF00462.24 OEU23133.1 - 4.9e-06 26.7 0.0 7.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SPP PF06550.11 OEU23134.1 - 0.14 11.6 8.6 0.22 10.9 8.6 1.3 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease DUF4191 PF13829.6 OEU23134.1 - 0.92 8.8 3.5 1.8 7.8 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Serglycin PF04360.12 OEU23134.1 - 9.3 6.2 10.0 19 5.2 10.0 1.4 1 0 0 1 1 1 0 Serglycin LRR19-TM PF15176.6 OEU23135.1 - 0.035 14.1 2.7 0.048 13.7 0.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain RseA_C PF03873.13 OEU23135.1 - 0.36 11.1 3.5 3.3 8.0 0.2 3.4 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain LRR_8 PF13855.6 OEU23136.1 - 5.2e-20 71.0 30.3 1.1e-06 28.3 0.8 6.4 3 3 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OEU23136.1 - 1.1e-17 63.9 22.5 0.00011 22.5 0.9 7.0 4 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU23136.1 - 3.5e-08 32.8 16.5 1.1 9.4 0.0 8.3 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 OEU23136.1 - 5.2e-08 32.4 21.0 0.85 10.4 0.1 8.9 10 0 0 10 10 10 4 Leucine Rich Repeat Exo_endo_phos PF03372.23 OEU23137.1 - 4.1e-07 29.7 0.1 9.5e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-bind_2 PF08914.11 OEU23137.1 - 0.015 15.4 0.2 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Rap1 Myb domain FerA PF08165.11 OEU23139.1 - 0.22 11.5 1.4 0.31 11.0 0.4 1.7 2 0 0 2 2 2 0 FerA (NUC095) domain Aldolase_II PF00596.21 OEU23143.1 - 5.2e-40 137.4 0.0 7.6e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HAD_2 PF13419.6 OEU23143.1 - 4e-05 23.8 0.1 8.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OEU23143.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 OEU23143.1 - 0.059 13.6 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Bap31 PF05529.12 OEU23144.1 - 2.4e-21 76.0 3.9 3.1e-21 75.6 3.9 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF1673 PF07895.11 OEU23144.1 - 0.022 14.5 0.7 2 8.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF465 PF04325.13 OEU23144.1 - 0.039 14.0 0.1 0.039 14.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) LapA_dom PF06305.11 OEU23144.1 - 1.8 8.4 7.2 3.9 7.4 0.1 3.0 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain Sulfate_transp PF00916.20 OEU23145.1 - 3.9e-32 111.4 30.5 3.9e-32 111.4 30.5 2.6 2 1 0 2 2 2 1 Sulfate permease family STAS PF01740.21 OEU23145.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OEU23145.1 - 0.085 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 OEU23145.1 - 1.6 9.2 30.4 0.43 11.0 4.4 3.5 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF1295 PF06966.12 OEU23147.1 - 6.2e-19 68.4 0.1 9.1e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OEU23147.1 - 0.003 16.4 0.2 0.024 13.4 0.0 2.0 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 OEU23147.1 - 0.0093 16.4 0.0 0.034 14.6 0.0 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 OEU23147.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OEU23147.1 - 0.18 12.2 4.2 0.25 11.8 0.1 3.1 2 1 0 2 2 2 0 Phospholipid methyltransferase DDE_Tnp_1_7 PF13843.6 OEU23149.1 - 0.00018 21.0 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 HA PF03457.14 OEU23150.1 - 9e-32 109.2 0.2 1.1e-14 54.5 0.1 2.6 2 0 0 2 2 2 2 Helicase associated domain OAD_gamma PF04277.13 OEU23151.1 - 2.5 8.7 6.7 9.9 6.8 0.0 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Mucin-like PF16058.5 OEU23151.1 - 7.4 6.7 14.3 0.03 14.4 4.0 2.3 3 0 0 3 3 3 0 Mucin-like GATase_3 PF07685.14 OEU23152.1 - 5.5e-27 94.6 0.2 1e-26 93.7 0.2 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Methyltransf_34 PF11312.8 OEU23153.1 - 0.0004 19.7 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase RL11D PF11088.8 OEU23154.1 - 0.016 15.5 5.6 2.7 8.3 0.2 2.9 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 Mt_ATP-synt_D PF05873.12 OEU23154.1 - 2 8.3 10.8 0.81 9.5 4.3 3.5 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DIMCO_N PF16844.5 OEU23154.1 - 2.2 8.6 9.0 3.2 8.1 0.2 3.9 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor, N-terminal SIR2 PF02146.17 OEU23155.1 - 0.00031 20.7 9.5 0.039 13.9 1.4 5.0 3 2 1 4 4 4 2 Sir2 family cEGF PF12662.7 OEU23155.1 - 0.13 12.3 3.8 0.44 10.5 0.8 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like Secretin_N_2 PF07655.13 OEU23155.1 - 2.7 8.6 29.7 4.3 7.9 12.5 3.7 4 0 0 4 4 4 0 Secretin N-terminal domain Gly_transf_sug PF04488.15 OEU23157.1 - 2.8e-12 47.1 0.0 1.3e-11 44.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU23157.1 - 5.4e-06 26.0 0.1 0.00037 19.9 0.0 2.4 1 1 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 OEU23157.1 - 2.1e-05 24.1 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gb3_synth PF04572.12 OEU23157.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region DUF2484 PF10658.9 OEU23157.1 - 0.095 13.0 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) 7tm_3 PF00003.22 OEU23158.1 - 1.6e-23 83.7 17.5 2.2e-23 83.2 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4512 PF14975.6 OEU23158.1 - 0.042 14.6 0.0 0.16 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Polysacc_synt PF01943.17 OEU23158.1 - 0.36 10.2 13.7 0.016 14.6 4.9 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TraL PF07178.11 OEU23158.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.9 4 1 1 5 5 5 0 TraL protein Adipogenin PF15202.6 OEU23158.1 - 0.52 10.4 7.4 2.5 8.2 0.5 3.3 3 0 0 3 3 3 0 Adipogenin DUF3357 PF11837.8 OEU23158.1 - 3 8.3 4.2 12 6.3 0.1 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3357) TPR_12 PF13424.6 OEU23159.1 - 1.1e-17 64.0 1.1 1.1e-08 35.2 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OEU23159.1 - 1.2e-11 44.1 2.2 0.0033 17.3 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OEU23159.1 - 2.2e-08 33.6 5.5 0.79 10.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OEU23159.1 - 2.2e-07 30.5 5.0 0.027 14.1 0.0 4.7 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.28 OEU23159.1 - 2.8e-06 26.9 7.5 0.17 11.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OEU23159.1 - 9.3e-06 25.5 3.4 6.4 7.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 OEU23159.1 - 0.0001 22.3 0.4 0.61 10.2 0.0 3.3 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 OEU23159.1 - 0.00011 22.0 1.2 0.11 12.6 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU23159.1 - 0.00082 20.0 0.0 19 6.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OEU23159.1 - 0.042 14.7 0.1 31 5.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OEU23159.1 - 0.087 12.3 1.2 1.2 8.6 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_5 PF12688.7 OEU23159.1 - 0.14 12.4 0.1 1.2 9.4 0.0 2.3 2 1 1 3 3 3 0 Tetratrico peptide repeat 2OG-FeII_Oxy_3 PF13640.6 OEU23160.1 - 2.2e-05 25.2 0.0 4.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.15 OEU23160.1 - 0.1 12.4 0.3 2.5 7.9 0.0 2.7 2 1 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase SNase PF00565.17 OEU23161.1 - 0.00015 22.2 0.0 0.00051 20.5 0.0 1.9 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Excalibur PF05901.11 OEU23161.1 - 0.00016 22.2 0.9 0.00063 20.3 0.9 2.0 1 0 0 1 1 1 1 Excalibur calcium-binding domain PorB PF11565.8 OEU23161.1 - 0.034 14.5 0.3 0.094 13.1 0.0 1.9 2 0 0 2 2 2 0 Alpha helical Porin B zf-C3HC4_3 PF13920.6 OEU23163.1 - 2.6e-10 40.0 11.9 6.2e-10 38.8 11.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OEU23163.1 - 0.0004 20.3 9.5 0.00066 19.6 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU23163.1 - 0.0036 17.1 11.2 0.03 14.2 11.2 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OEU23163.1 - 0.012 15.6 1.0 0.012 15.6 1.0 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OEU23163.1 - 0.23 11.3 12.4 0.23 11.3 6.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S49_N PF08496.10 OEU23163.1 - 0.39 10.8 1.6 1.3 9.1 0.1 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MscS_TM PF12794.7 OEU23163.1 - 0.49 9.2 0.0 0.49 9.2 0.0 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF2489 PF10675.9 OEU23163.1 - 2.3 8.1 7.9 0.77 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DNA_pol_phi PF04931.13 OEU23164.1 - 0.1 10.7 2.5 0.11 10.6 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 OEU23164.1 - 1.4 7.6 6.7 1.8 7.2 6.7 1.2 1 0 0 1 1 1 0 Presenilin TPMT PF05724.11 OEU23165.1 - 1.6e-36 126.0 0.0 9.8e-36 123.5 0.0 2.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OEU23165.1 - 0.0033 17.3 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU23165.1 - 0.0038 17.9 2.2 0.017 15.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain CysG_dimeriser PF10414.9 OEU23166.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region DUF3139 PF11337.8 OEU23166.1 - 2.7 8.7 6.0 82 3.9 6.0 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Utp14 PF04615.13 OEU23167.1 - 0.055 12.1 35.0 0.16 10.5 22.2 2.2 2 0 0 2 2 2 0 Utp14 protein Phage_tail_T PF06223.12 OEU23167.1 - 0.11 13.1 1.0 4 8.0 0.1 2.8 2 0 0 2 2 2 0 Minor tail protein T Ecm33 PF12454.8 OEU23167.1 - 1.6 8.9 8.1 0.3 11.3 3.0 2.4 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein DUF572 PF04502.13 OEU23167.1 - 2 7.9 42.4 1.5 8.4 25.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF572) DUF2201_N PF13203.6 OEU23167.1 - 7.2 6.1 15.8 2.1 7.9 3.4 2.8 2 1 0 2 2 2 0 Putative metallopeptidase domain Tetraspanin PF00335.20 OEU23168.1 - 0.37 10.5 4.3 3.3 7.4 0.7 2.1 2 0 0 2 2 2 0 Tetraspanin family DUF4134 PF13572.6 OEU23168.1 - 1.5 9.2 7.3 0.31 11.4 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) PARP PF00644.20 OEU23170.1 - 6.1e-07 29.2 0.8 2.5e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain CENP-B_dimeris PF09026.10 OEU23170.1 - 0.0031 17.9 3.3 0.0031 17.9 3.3 3.1 3 0 0 3 3 3 1 Centromere protein B dimerisation domain ADK PF00406.22 OEU23171.1 - 3e-51 173.5 0.0 4.3e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OEU23171.1 - 2.4e-21 76.6 0.0 4.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 OEU23171.1 - 1.9e-14 53.3 0.0 3.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OEU23171.1 - 0.00011 22.3 0.0 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU23171.1 - 0.001 19.6 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 OEU23171.1 - 0.21 11.8 8.1 0.48 10.7 0.3 3.2 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain CRAL_TRIO PF00650.20 OEU23172.1 - 3.8e-17 62.5 1.4 2.4e-15 56.6 1.4 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain DegS PF05384.11 OEU23175.1 - 0.0071 15.8 3.1 0.015 14.8 3.1 1.5 1 0 0 1 1 1 1 Sensor protein DegS ATG22 PF11700.8 OEU23176.1 - 5.8e-21 74.7 34.1 1.9e-19 69.6 34.1 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OEU23176.1 - 7.4e-10 38.3 31.1 7.4e-10 38.3 31.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily O-FucT PF10250.9 OEU23177.1 - 3.1e-53 181.6 0.1 4.9e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EDR1 PF14381.6 OEU23177.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Rod_cone_degen PF15201.6 OEU23177.1 - 0.094 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Progressive rod-cone degeneration BTB PF00651.31 OEU23178.1 - 9.3e-05 22.6 0.7 0.0021 18.3 0.7 2.6 1 1 0 1 1 1 1 BTB/POZ domain BicD PF09730.9 OEU23178.1 - 0.0056 15.2 7.2 0.0074 14.8 7.2 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Exonuc_VII_L PF02601.15 OEU23178.1 - 0.033 13.8 2.6 0.045 13.3 2.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Leu_zip PF15294.6 OEU23178.1 - 0.073 12.6 8.8 0.11 11.9 8.8 1.2 1 0 0 1 1 1 0 Leucine zipper FOXP-CC PF16159.5 OEU23178.1 - 0.22 12.2 2.7 2 9.1 0.3 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain YtxH PF12732.7 OEU23178.1 - 0.63 10.6 4.2 4 8.0 4.2 2.2 1 1 0 1 1 1 0 YtxH-like protein OmpH PF03938.14 OEU23178.1 - 0.9 9.9 13.3 0.18 12.1 9.7 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) KxDL PF10241.9 OEU23178.1 - 2 8.8 7.4 5 7.5 7.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Atg14 PF10186.9 OEU23178.1 - 4.6 6.2 14.0 7.3 5.6 14.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 OEU23178.1 - 7.8 6.8 7.4 20 5.4 7.4 1.7 1 0 0 1 1 1 0 Haemolysin XhlA CDC48_N PF02359.18 OEU23180.1 - 0.051 13.8 0.0 0.56 10.4 0.0 2.4 2 1 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain AAA PF00004.29 OEU23181.1 - 7.1e-51 172.1 0.0 5.4e-38 130.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU23181.1 - 8.7e-09 36.0 0.0 0.0035 17.7 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 OEU23181.1 - 4.1e-07 30.3 0.0 0.0022 18.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OEU23181.1 - 1.3e-06 27.9 0.0 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OEU23181.1 - 2.3e-06 27.9 1.5 0.013 15.8 0.3 4.1 2 2 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OEU23181.1 - 3.8e-06 27.0 0.1 0.0014 18.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OEU23181.1 - 4.3e-06 26.8 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 OEU23181.1 - 4.4e-06 26.4 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OEU23181.1 - 8.1e-06 25.7 0.2 0.029 14.1 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 OEU23181.1 - 8.3e-06 25.3 0.2 0.092 12.1 0.0 3.6 2 1 1 3 3 3 2 Bacterial TniB protein RNA_helicase PF00910.22 OEU23181.1 - 2.3e-05 24.7 0.0 0.069 13.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 OEU23181.1 - 2.9e-05 23.5 0.2 0.0021 17.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OEU23181.1 - 0.00044 19.8 0.0 0.084 12.4 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 OEU23181.1 - 0.00052 19.8 0.5 0.95 9.1 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 OEU23181.1 - 0.00078 19.2 0.0 0.082 12.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 OEU23181.1 - 0.00088 19.3 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OEU23181.1 - 0.0013 18.2 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.6 OEU23181.1 - 0.0014 18.8 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OEU23181.1 - 0.0023 18.5 0.0 0.31 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IPT PF01745.16 OEU23181.1 - 0.0032 16.9 0.0 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Isopentenyl transferase NACHT PF05729.12 OEU23181.1 - 0.005 16.8 0.0 0.88 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 OEU23181.1 - 0.0091 15.6 0.3 3.3 7.2 0.0 3.0 3 1 0 3 3 3 1 AAA domain Rad17 PF03215.15 OEU23181.1 - 0.0098 15.8 0.2 0.17 11.8 0.0 3.0 4 1 0 4 4 4 1 Rad17 P-loop domain AAA_3 PF07726.11 OEU23181.1 - 0.011 15.6 0.0 0.086 12.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OEU23181.1 - 0.011 15.6 0.0 3 7.7 0.0 3.3 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 OEU23181.1 - 0.011 16.1 0.1 1.5 9.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OEU23181.1 - 0.014 15.2 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OEU23181.1 - 0.014 14.9 0.0 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 OEU23181.1 - 0.014 15.9 0.4 0.054 14.0 0.1 2.1 3 0 0 3 3 1 0 ABC transporter NB-ARC PF00931.22 OEU23181.1 - 0.014 14.6 0.0 0.61 9.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.10 OEU23181.1 - 0.015 14.7 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 OEU23181.1 - 0.028 14.7 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OEU23181.1 - 0.052 12.8 0.0 8 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 OEU23181.1 - 0.1 11.7 0.0 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 OEU23181.1 - 0.11 12.5 0.1 28 4.6 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OEU23181.1 - 0.14 12.4 0.0 0.81 10.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 OEU23181.1 - 0.21 11.0 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 YfdX PF10938.8 OEU23181.1 - 0.22 11.5 1.1 0.4 10.6 1.1 1.4 1 0 0 1 1 1 0 YfdX protein DUF3649 PF12365.8 OEU23182.1 - 0.29 10.9 1.5 0.57 10.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) HSF_DNA-bind PF00447.17 OEU23183.1 - 9.8e-19 67.8 0.6 1.8e-18 67.0 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PhzC-PhzF PF02567.16 OEU23184.1 - 7.9e-10 38.7 1.1 3.3e-07 30.1 0.0 3.2 2 2 0 3 3 3 2 Phenazine biosynthesis-like protein UDPGT PF00201.18 OEU23186.1 - 1.8e-12 46.9 0.1 5.8e-12 45.2 0.1 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OEU23186.1 - 7.4e-09 35.8 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SET PF00856.28 OEU23187.1 - 5.9e-10 39.8 5.7 2.2e-09 38.0 3.1 2.6 2 1 0 2 2 2 1 SET domain YhzD PF14120.6 OEU23187.1 - 0.054 13.6 0.4 0.17 12.0 0.4 1.8 1 0 0 1 1 1 0 YhzD-like protein zf-MYND PF01753.18 OEU23188.1 - 3e-18 65.6 29.6 2.9e-09 36.9 10.7 2.4 2 0 0 2 2 2 2 MYND finger zf-Mss51 PF13824.6 OEU23188.1 - 0.016 15.3 19.2 0.11 12.7 3.6 2.5 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 MPTase-PolyVal PF18818.1 OEU23188.1 - 0.33 11.0 1.5 9.8 6.2 0.2 2.5 3 0 0 3 3 3 0 Metallopeptidase superfamily domain zf-C2H2_10 PF16588.5 OEU23189.1 - 2.2 8.1 16.5 12 5.8 0.7 3.9 3 0 0 3 3 3 0 C2H2 zinc-finger Cortex-I_coil PF09304.10 OEU23191.1 - 1.2 9.4 30.2 0.22 11.8 2.4 3.4 2 1 1 3 3 3 0 Cortexillin I, coiled coil TPR_1 PF00515.28 OEU23192.1 - 1.3e-24 85.0 12.6 0.00033 20.3 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 OEU23192.1 - 2.4e-19 67.8 9.8 9.7e-05 22.2 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OEU23192.1 - 2.4e-17 62.3 4.3 6.2e-11 41.8 0.1 6.0 5 1 1 6 6 6 2 TPR repeat TPR_12 PF13424.6 OEU23192.1 - 6.7e-12 45.5 3.1 0.00021 21.5 0.3 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU23192.1 - 1.5e-11 44.1 0.0 0.049 14.5 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OEU23192.1 - 2.5e-11 42.9 9.7 0.066 13.5 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OEU23192.1 - 1.3e-09 38.4 4.2 0.0093 16.5 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OEU23192.1 - 1.7e-09 37.4 4.9 0.0094 16.3 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OEU23192.1 - 1.9e-08 33.8 4.4 1.2 9.3 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OEU23192.1 - 1.1e-05 25.8 4.8 1.3 9.8 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OEU23192.1 - 1.6e-05 25.4 1.1 0.06 14.0 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OEU23192.1 - 0.00095 19.3 0.0 4.9 7.4 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OEU23192.1 - 0.0036 17.5 5.1 0.024 14.9 0.1 3.5 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 OEU23192.1 - 0.011 15.2 2.5 0.05 13.1 0.1 2.9 3 0 0 3 3 3 0 SHNi-TPR HIP1_clath_bdg PF16515.5 OEU23192.1 - 0.12 13.0 5.9 0.13 12.9 0.3 3.1 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SIX1_SD PF16878.5 OEU23192.1 - 0.17 12.4 1.4 1.2 9.6 0.2 2.8 2 1 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain FRB_dom PF08771.11 OEU23192.1 - 0.24 11.8 2.6 0.86 10.1 0.5 2.9 2 2 0 2 2 2 0 FKBP12-rapamycin binding domain DUF3486 PF11985.8 OEU23192.1 - 0.78 10.1 6.5 0.26 11.7 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3486) MIT PF04212.18 OEU23192.1 - 4.3 7.5 12.5 4.5 7.4 1.6 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Exonuc_VII_S PF02609.16 OEU23192.1 - 4.7 7.4 8.1 85 3.3 0.1 4.8 5 0 0 5 5 5 0 Exonuclease VII small subunit zf-RanBP PF00641.18 OEU23193.1 - 0.0064 15.8 5.7 0.0064 15.8 5.7 2.9 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 OEU23193.1 - 0.38 10.9 5.3 7 6.8 1.4 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger CENP-B_dimeris PF09026.10 OEU23193.1 - 1 9.8 16.5 0.31 11.5 9.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FYDLN_acid PF09538.10 OEU23193.1 - 3.1 8.5 17.5 2.8 8.7 6.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 OEU23193.1 - 3.2 7.9 8.9 8.1 6.6 8.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon Sulfatase PF00884.23 OEU23194.1 - 4.7e-46 157.6 6.3 4.7e-46 157.6 6.3 1.9 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 OEU23194.1 - 7.1e-08 32.4 0.3 0.00044 19.9 0.5 2.7 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OEU23194.1 - 9.4e-07 29.0 0.5 2.1e-06 28.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF202 PF02656.15 OEU23195.1 - 1.5e-14 54.1 3.1 1.2e-13 51.3 0.6 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF202) Epimerase PF01370.21 OEU23200.1 - 2.7e-15 56.5 0.1 3.1e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OEU23200.1 - 1.3e-13 51.0 0.1 1.5e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OEU23200.1 - 7.3e-12 44.9 0.9 8.8e-12 44.6 0.9 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OEU23200.1 - 9.6e-09 35.4 0.1 3e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OEU23200.1 - 1.5e-07 30.9 0.1 2.8e-07 30.0 0.1 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OEU23200.1 - 1.9e-05 24.0 0.2 2.3e-05 23.7 0.2 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OEU23200.1 - 2e-05 24.6 0.2 3.6e-05 23.8 0.2 1.3 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OEU23200.1 - 2.1e-05 24.2 0.6 3e-05 23.7 0.6 1.3 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OEU23200.1 - 0.003 16.7 0.1 0.0073 15.4 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 OEU23200.1 - 0.034 14.3 0.7 0.065 13.3 0.7 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_28 PF00295.17 OEU23201.1 - 1.4e-19 70.4 0.3 1.1e-18 67.4 0.3 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 OEU23201.1 - 7.9e-10 38.9 1.3 1.3e-06 28.5 0.1 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein UDPGT PF00201.18 OEU23204.1 - 4.4e-07 29.1 0.0 5.7e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase MBOAT_2 PF13813.6 OEU23205.1 - 1.1e-14 54.5 1.1 1.1e-14 54.5 1.1 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family 2OG-FeII_Oxy_2 PF13532.6 OEU23207.1 - 7.8e-24 84.9 2.2 1.6e-23 83.9 2.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OEU23207.1 - 0.0012 19.3 0.1 0.0028 18.1 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SUIM_assoc PF16619.5 OEU23207.1 - 0.16 12.1 20.6 0.5 10.5 4.6 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-RING_4 PF14570.6 OEU23208.1 - 1.4e-12 47.1 13.9 3.2e-12 46.0 13.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OEU23208.1 - 0.00096 19.0 9.6 0.002 17.9 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sec20 PF03908.13 OEU23208.1 - 0.052 13.5 0.4 0.56 10.2 0.0 2.7 3 0 0 3 3 3 0 Sec20 DZR PF12773.7 OEU23208.1 - 0.94 9.6 11.4 0.21 11.7 0.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon Pro_isomerase PF00160.21 OEU23209.1 - 1.1e-42 146.0 0.0 1.2e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DSPc PF00782.20 OEU23210.1 - 9.7e-09 35.1 0.1 1.2e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OEU23210.1 - 0.00019 21.1 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 OEU23210.1 - 0.011 15.4 0.2 0.014 15.1 0.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3742 PF12553.8 OEU23211.1 - 0.24 11.5 0.5 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) Ank_2 PF12796.7 OEU23212.1 - 0.11 13.1 0.0 0.33 11.6 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) SopA PF13981.6 OEU23212.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 SopA-like central domain 2-Hacid_dh_C PF02826.19 OEU23213.1 - 6.8e-44 149.3 0.2 8.8e-42 142.5 0.2 2.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OEU23213.1 - 3e-16 59.3 0.0 3.6e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F-box-like PF12937.7 OEU23214.1 - 0.00078 19.3 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OEU23214.1 - 0.0017 18.1 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OEU23214.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box Sep15_SelM PF08806.11 OEU23214.1 - 0.097 12.8 0.0 0.85 9.8 0.0 2.4 2 0 0 2 2 2 0 Sep15/SelM redox domain PRA-CH PF01502.18 OEU23215.1 - 3.2e-20 71.7 5.4 6.5e-18 64.3 5.4 2.5 1 1 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OEU23215.1 - 2.7e-15 56.6 0.3 3.8e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OEU23215.1 - 1.3e-05 25.3 0.4 2.2e-05 24.5 0.4 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 OEU23215.1 - 0.016 15.4 0.2 0.028 14.7 0.2 1.3 1 0 0 1 1 1 0 MazG-like family VapB_antitoxin PF09957.9 OEU23215.1 - 0.03 14.2 0.7 0.067 13.1 0.7 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB AIG1 PF04548.16 OEU23217.1 - 0.017 14.5 0.3 0.044 13.1 0.1 1.8 2 0 0 2 2 2 0 AIG1 family Arm_vescicular PF18770.1 OEU23217.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor FAD_binding_4 PF01565.23 OEU23219.1 - 1.3e-10 41.1 0.8 9.7e-10 38.3 0.8 2.3 1 1 0 1 1 1 1 FAD binding domain PseudoU_synth_2 PF00849.22 OEU23220.1 - 6.4e-12 45.9 0.7 0.00011 22.4 0.0 3.2 3 1 0 3 3 3 2 RNA pseudouridylate synthase XFP_N PF09364.10 OEU23220.1 - 0.00015 20.7 0.1 0.00027 19.9 0.1 1.3 1 0 0 1 1 1 1 XFP N-terminal domain PT PF04886.12 OEU23221.1 - 0.061 12.9 8.6 0.14 11.7 8.6 1.6 1 0 0 1 1 1 0 PT repeat Gly_transf_sug PF04488.15 OEU23223.1 - 2e-07 31.5 0.0 5.1e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SBE2 PF17076.5 OEU23223.1 - 0.098 10.9 0.5 0.38 8.9 0.2 1.8 2 0 0 2 2 2 0 SBE2, cell-wall formation FAD_binding_3 PF01494.19 OEU23224.1 - 0.00015 21.1 0.1 0.00029 20.2 0.1 1.4 1 1 1 2 2 2 1 FAD binding domain DUF3721 PF12518.8 OEU23224.1 - 0.015 15.1 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function zf-C2H2_11 PF16622.5 OEU23227.1 - 4.2 7.2 9.5 0.75 9.6 0.2 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type Trp_halogenase PF04820.14 OEU23228.1 - 5e-05 22.3 0.0 0.062 12.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 OEU23228.1 - 0.0045 17.2 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OEU23228.1 - 0.0048 16.2 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OEU23228.1 - 0.0081 16.2 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OEU23228.1 - 0.044 13.0 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OEU23228.1 - 0.051 14.1 0.0 0.096 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLN5 PF15014.6 OEU23228.1 - 0.17 11.5 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 5 Thi4 PF01946.17 OEU23228.1 - 0.18 11.0 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family zf-C3HC4_3 PF13920.6 OEU23230.1 - 7e-12 45.0 9.7 1.5e-11 43.9 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OEU23230.1 - 2.5e-06 27.2 11.3 5.8e-06 26.1 11.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OEU23230.1 - 0.0061 16.4 11.4 0.011 15.5 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Spc24 PF08286.11 OEU23230.1 - 0.53 10.5 0.1 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-P11 PF03854.14 OEU23230.1 - 0.61 9.8 5.4 1.1 9.0 5.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger Sec3_C_2 PF15278.6 OEU23230.1 - 6.6 7.2 6.6 1.5 9.2 0.7 2.5 2 1 1 3 3 3 0 Sec3 exocyst complex subunit DTW PF03942.15 OEU23231.1 - 2.4e-31 109.0 13.5 3.3e-30 105.3 4.7 3.2 2 1 0 3 3 3 2 DTW domain FR47 PF08445.10 OEU23231.1 - 3e-10 39.9 0.0 7.3e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 OEU23231.1 - 1.3e-07 31.9 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OEU23231.1 - 1.4e-05 25.8 0.1 0.00023 21.9 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OEU23231.1 - 0.00027 21.3 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OEU23231.1 - 0.0028 17.6 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DivIC PF04977.15 OEU23231.1 - 0.48 10.2 5.1 1.1 9.0 5.1 1.6 1 0 0 1 1 1 0 Septum formation initiator p450 PF00067.22 OEU23232.1 - 2.6e-57 194.6 0.0 4.2e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OEU23232.1 - 2.9e-41 141.5 0.0 5.4e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OEU23232.1 - 2.1e-18 66.9 0.1 5.3e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OEU23232.1 - 4.4e-15 56.3 0.0 1.2e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OEU23232.1 - 0.0002 21.6 0.0 0.00075 19.8 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain PGM_PMM_I PF02878.16 OEU23232.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Serinc PF03348.15 OEU23233.1 - 0.17 10.8 4.5 0.34 9.8 4.5 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) WSD PF15613.6 OEU23233.1 - 0.18 12.3 6.2 0.71 10.4 6.2 2.0 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF243 PF03103.17 OEU23233.1 - 0.22 11.8 9.4 0.42 11.0 6.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DUF4746 PF15928.5 OEU23233.1 - 3.3 7.1 9.8 0.32 10.4 5.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Rrp15p PF07890.12 OEU23233.1 - 4.6 7.6 15.0 1.7 9.0 11.2 2.3 2 0 0 2 2 2 0 Rrp15p SprA-related PF12118.8 OEU23233.1 - 8.3 5.4 25.8 0.065 12.4 17.4 1.7 2 0 0 2 2 2 0 SprA-related family TraE PF05309.11 OEU23234.1 - 1 8.7 2.6 2.3 7.6 0.1 2.2 2 1 0 2 2 2 0 TraE protein UT PF03253.14 OEU23235.1 - 3.9e-37 128.0 18.5 2.3e-36 125.4 18.5 1.9 1 1 0 1 1 1 1 Urea transporter ATP-synt_B PF00430.18 OEU23235.1 - 0.062 13.4 0.3 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1690 PF07956.11 OEU23235.1 - 1.8 9.0 8.4 0.34 11.3 3.3 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF334 PF03904.13 OEU23235.1 - 1.8 8.1 8.2 4.7 6.7 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Prominin PF05478.11 OEU23235.1 - 9.7 4.0 14.0 5.4 4.9 4.9 1.9 1 1 0 1 1 1 0 Prominin MFS_1 PF07690.16 OEU23238.1 - 2e-30 105.9 12.8 2.9e-21 75.8 0.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OEU23238.1 - 4.4e-20 71.6 9.8 7.9e-20 70.7 1.5 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 OEU23238.1 - 1.2e-05 24.4 23.4 0.0014 17.6 8.6 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter PAN_1 PF00024.26 OEU23239.1 - 0.00067 19.6 0.3 0.00067 19.6 0.3 2.5 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 OEU23239.1 - 0.0055 16.6 0.5 0.0055 16.6 0.5 2.9 3 1 0 3 3 3 1 PAN domain WD40 PF00400.32 OEU23240.1 - 6.8e-10 39.4 7.3 1.3e-05 25.9 0.2 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 OEU23240.1 - 0.00083 19.2 4.5 0.27 11.2 0.1 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OEU23240.1 - 0.0014 18.6 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OEU23240.1 - 0.0015 18.8 0.0 5.2 7.4 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OEU23240.1 - 0.0079 15.2 0.0 1.1 8.2 0.0 2.9 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OEU23240.1 - 0.0086 14.8 0.2 1.2 7.7 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 IKI3 PF04762.12 OEU23240.1 - 0.016 13.2 0.1 0.61 8.0 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Lactonase PF10282.9 OEU23240.1 - 0.061 12.6 0.1 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller RRM_1 PF00076.22 OEU23243.1 - 7.2e-20 70.6 0.0 2.5e-10 40.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OEU23243.1 - 3.4e-05 23.9 0.0 0.14 12.3 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif GlcNAc-1_reg PF18440.1 OEU23243.1 - 0.043 14.0 0.0 1.1 9.5 0.0 2.7 2 1 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain PHM7_cyt PF14703.6 OEU23243.1 - 0.064 13.5 0.3 2.3 8.4 0.0 2.6 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter PrpF PF04303.13 OEU23244.1 - 9.7e-69 232.1 0.8 1.1e-68 231.9 0.8 1.0 1 0 0 1 1 1 1 PrpF protein NAD_binding_10 PF13460.6 OEU23245.1 - 7.7e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU23245.1 - 2.1e-06 27.5 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OEU23245.1 - 9.9e-05 21.9 0.1 0.085 12.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Tir_receptor_C PF07489.11 OEU23246.1 - 0.2 11.6 4.0 0.24 11.4 4.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TFB6 PF17110.5 OEU23246.1 - 7 6.4 8.0 11 5.8 8.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 OEU23247.1 - 0.31 9.2 13.4 0.33 9.1 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 OEU23247.1 - 0.56 10.5 9.3 0.71 10.2 8.9 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 POX PF07526.11 OEU23247.1 - 0.61 10.7 3.8 0.43 11.1 1.1 1.9 1 1 1 2 2 2 0 Associated with HOX DUF3644 PF12358.8 OEU23247.1 - 1.1 9.7 7.9 0.33 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) DUF2237 PF09996.9 OEU23248.1 - 8.8e-10 38.6 6.5 2.2e-09 37.3 2.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2237) NCA2 PF08637.10 OEU23249.1 - 8.6e-18 64.5 0.2 8.6e-18 64.5 0.2 3.2 4 0 0 4 4 4 1 ATP synthase regulation protein NCA2 DUF4834 PF16118.5 OEU23249.1 - 8.6 7.4 20.3 1.9 9.5 2.1 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) SLATT_4 PF18186.1 OEU23250.1 - 1.4 8.6 3.4 0.99 9.0 0.9 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Mur_ligase_M PF08245.12 OEU23251.1 - 6.3e-06 26.3 0.0 0.00038 20.5 0.0 2.8 1 1 1 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OEU23251.1 - 0.00029 21.0 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain SpoIIIAH PF12685.7 OEU23251.1 - 0.54 10.0 8.6 0.11 12.3 0.5 3.0 3 0 0 3 3 3 0 SpoIIIAH-like protein Ribonuc_P_40 PF08584.11 OEU23252.1 - 0.00096 18.5 1.9 0.002 17.5 1.9 1.5 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit LRR_6 PF13516.6 OEU23253.1 - 1.7 8.9 6.6 3.9 7.8 3.3 2.6 2 0 0 2 2 2 0 Leucine Rich repeat Peptidase_S9_N PF02897.15 OEU23254.1 - 7.1e-60 202.9 7.6 7.1e-60 202.9 7.6 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OEU23254.1 - 2.4e-52 177.5 0.0 4.9e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pox_Ag35 PF03286.14 OEU23255.1 - 0.25 11.1 13.9 0.32 10.8 13.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CLN3 PF02487.17 OEU23255.1 - 0.25 10.3 1.2 0.31 10.1 1.2 1.0 1 0 0 1 1 1 0 CLN3 protein DUF678 PF05077.12 OEU23255.1 - 8.3 6.6 6.8 3.7 7.8 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF678) CSRNP_N PF16019.5 OEU23255.1 - 8.9 6.2 9.9 7.4 6.4 8.8 1.3 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Macoilin PF09726.9 OEU23255.1 - 8.9 4.7 16.4 9.7 4.6 16.4 1.0 1 0 0 1 1 1 0 Macoilin family eRF1_1 PF03463.15 OEU23257.1 - 1.7e-38 131.5 1.1 3.3e-38 130.6 1.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 OEU23257.1 - 9.1e-23 81.0 0.2 1.5e-22 80.3 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OEU23257.1 - 3.8e-20 72.5 0.1 2.1e-19 70.1 0.0 2.3 2 0 0 2 2 2 1 eRF1 domain 3 NTP_transf_6 PF06042.11 OEU23257.1 - 0.12 12.3 4.6 0.31 10.9 4.6 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase SCHIP-1 PF10148.9 OEU23259.1 - 0.17 11.4 2.6 0.3 10.7 2.6 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Trimer_CC PF08954.11 OEU23259.1 - 0.65 9.6 5.2 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Trimerisation motif DUF913 PF06025.12 OEU23262.1 - 0.05 12.6 1.9 0.076 12.0 1.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2971 PF11185.8 OEU23262.1 - 0.16 13.1 3.8 1.3 10.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2971) EOS1 PF12326.8 OEU23262.1 - 0.24 11.3 1.6 1.4 8.8 0.7 2.1 2 0 0 2 2 2 0 N-glycosylation protein Peptidase_S49_N PF08496.10 OEU23262.1 - 0.56 10.3 4.0 1 9.4 4.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 OEU23262.1 - 3.3 7.4 5.9 5.7 6.6 4.7 1.8 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 OEU23262.1 - 4.1 6.1 11.7 4.8 5.8 8.9 1.9 2 0 0 2 2 2 0 Presenilin DCP2 PF05026.13 OEU23264.1 - 2.9e-21 75.6 2.1 4.1e-21 75.1 2.1 1.2 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OEU23264.1 - 5.5e-10 39.4 0.0 9.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Shisa PF13908.6 OEU23265.1 - 0.0015 18.8 0.6 0.0015 18.8 0.6 3.1 3 1 1 4 4 4 1 Wnt and FGF inhibitory regulator PPR_1 PF12854.7 OEU23267.1 - 2.1e-39 132.9 0.6 0.00033 20.3 0.0 13.1 14 0 0 14 14 14 7 PPR repeat PPR_2 PF13041.6 OEU23267.1 - 9.8e-39 131.3 13.8 2.3e-08 34.1 0.4 10.2 7 5 1 8 8 8 7 PPR repeat family PPR PF01535.20 OEU23267.1 - 1.6e-36 122.0 18.0 0.0001 22.3 0.0 14.4 15 2 0 15 15 14 6 PPR repeat PPR_3 PF13812.6 OEU23267.1 - 4.9e-27 93.8 0.2 0.00052 20.0 0.1 9.6 7 4 2 9 9 9 6 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU23267.1 - 2.6e-20 72.7 2.4 6.1e-08 32.3 0.1 5.3 1 1 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP Wzy_C_2 PF11846.8 OEU23267.1 - 1.6e-06 28.2 0.0 11 5.9 0.0 6.0 3 1 3 6 6 6 1 Virulence factor membrane-bound polymerase, C-terminal Ca_bind_SSO6904 PF18249.1 OEU23267.1 - 0.00022 21.5 0.0 9.6 6.6 0.0 4.9 5 0 0 5 5 5 1 Calcium binding protein SSO6904 TPR_14 PF13428.6 OEU23267.1 - 0.0003 21.4 0.0 1.1e+02 4.0 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ATP13 PF12921.7 OEU23267.1 - 0.0034 17.2 1.9 8.2 6.3 0.0 5.4 3 2 2 5 5 5 1 Mitochondrial ATPase expression TPR_6 PF13174.6 OEU23267.1 - 0.0038 17.7 0.0 14 6.6 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4752 PF15944.5 OEU23267.1 - 0.011 15.8 0.0 1.5 9.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4752) MRP-S27 PF10037.9 OEU23267.1 - 0.013 14.4 0.1 1.9 7.3 0.0 3.6 4 1 0 4 4 4 0 Mitochondrial 28S ribosomal protein S27 YfdX PF10938.8 OEU23267.1 - 0.11 12.5 0.1 13 5.7 0.1 3.9 3 0 0 3 3 3 0 YfdX protein TPR_4 PF07721.14 OEU23267.1 - 0.6 10.9 3.8 14 6.6 0.1 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TetR_C_8 PF14278.6 OEU23267.1 - 1.4 9.1 4.1 68 3.6 0.0 4.9 7 0 0 7 7 7 0 Transcriptional regulator C-terminal region HA PF03457.14 OEU23268.1 - 3.1e-31 107.5 5.4 5.7e-15 55.4 0.1 3.3 2 1 1 3 3 3 3 Helicase associated domain YL1 PF05764.13 OEU23268.1 - 0.046 13.8 0.4 0.077 13.1 0.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Trypsin PF00089.26 OEU23270.1 - 2.1e-19 70.2 0.1 2.5e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin CDKN3 PF05706.12 OEU23271.1 - 0.00015 21.5 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 OEU23271.1 - 0.00041 20.0 0.2 0.0037 16.9 0.0 2.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OEU23271.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OEU23271.1 - 0.063 13.4 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF5496 PF17600.2 OEU23271.1 - 0.13 12.3 0.2 0.31 11.1 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5496) Diphthamide_syn PF01866.17 OEU23273.1 - 1e-94 317.4 0.0 1e-94 317.4 0.0 1.4 2 0 0 2 2 2 1 Putative diphthamide synthesis protein SH3_6 PF12913.7 OEU23274.1 - 0.11 12.0 0.2 0.28 10.8 0.2 1.7 1 1 0 1 1 1 0 SH3 domain (SH3b1 type) RVT_1 PF00078.27 OEU23275.1 - 2e-07 30.8 0.0 6.3e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OEU23275.1 - 0.079 13.7 1.1 0.31 11.8 1.1 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase SSP160 PF06933.11 OEU23275.1 - 0.21 9.7 11.2 0.47 8.6 11.2 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PDZ_6 PF17820.1 OEU23276.1 - 0.00011 22.0 0.1 0.00031 20.5 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OEU23276.1 - 0.0038 17.6 0.2 0.011 16.0 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OEU23276.1 - 0.0062 16.8 0.3 0.023 15.0 0.3 2.0 1 0 0 1 1 1 1 PDZ domain NID PF07292.13 OEU23276.1 - 0.3 11.7 2.8 0.79 10.4 0.9 2.8 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Ank_4 PF13637.6 OEU23277.1 - 0.061 13.9 0.0 0.34 11.5 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LRR_4 PF12799.7 OEU23278.1 - 9.2 6.9 11.5 24 5.5 0.3 4.0 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) DUF643 PF04867.12 OEU23279.1 - 0.00044 20.8 1.7 0.0031 18.1 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF643) MotA_ExbB PF01618.16 OEU23282.1 - 0.1 12.4 1.4 0.22 11.3 0.1 2.2 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family APG6_N PF17675.1 OEU23282.1 - 3.6 8.1 23.4 1.7 9.2 0.7 3.5 3 0 0 3 3 3 0 Apg6 coiled-coil region Peptidase_S8 PF00082.22 OEU23283.1 - 2.6e-28 99.1 6.0 3.7e-28 98.7 6.0 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OEU23283.1 - 4.2e-21 74.8 0.8 8.9e-21 73.7 0.8 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain ASFV_J13L PF05568.11 OEU23284.1 - 0.19 11.5 3.6 0.3 10.8 3.6 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein 7tm_3 PF00003.22 OEU23285.1 - 2.7e-17 63.3 25.4 2.7e-17 63.3 25.4 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Phage_holin_2_3 PF16080.5 OEU23285.1 - 0.035 13.9 3.3 6.8 6.5 0.2 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF2407_C PF13373.6 OEU23285.1 - 0.41 10.8 0.9 0.73 10.0 0.9 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Cwf_Cwc_15 PF04889.12 OEU23286.1 - 0.0026 17.5 4.4 0.0026 17.5 4.4 3.2 3 0 0 3 3 3 2 Cwf15/Cwc15 cell cycle control protein DUF4083 PF13314.6 OEU23286.1 - 0.16 11.9 0.7 0.82 9.7 0.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Gly_transf_sug PF04488.15 OEU23287.1 - 4.8e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SAP PF02037.27 OEU23288.1 - 9.7e-06 25.2 0.7 0.018 14.8 0.0 2.6 3 0 0 3 3 3 2 SAP domain PASTA PF03793.19 OEU23288.1 - 0.086 12.7 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 PASTA domain DUF3357 PF11837.8 OEU23288.1 - 0.14 12.6 0.3 0.57 10.7 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) CCDC106 PF15794.5 OEU23288.1 - 5.5 6.6 13.2 1 9.0 9.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 O-antigen_lig PF13425.6 OEU23288.1 - 9.2 4.9 6.2 1.1 8.0 0.5 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SelR PF01641.18 OEU23290.1 - 4e-32 110.8 0.0 6.1e-32 110.2 0.0 1.3 1 1 0 1 1 1 1 SelR domain CIAPIN1 PF05093.13 OEU23290.1 - 0.048 14.2 0.2 0.084 13.4 0.0 1.4 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Prim_Zn_Ribbon PF08273.12 OEU23290.1 - 0.052 13.8 2.7 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase GFA PF04828.14 OEU23290.1 - 0.056 13.8 0.2 1.7 9.0 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 OEU23290.1 - 0.076 13.2 0.2 0.66 10.2 0.2 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-FLZ PF04570.14 OEU23290.1 - 0.097 12.2 0.8 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DNA_RNApol_7kD PF03604.13 OEU23290.1 - 0.77 9.5 6.7 14 5.5 1.3 3.1 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Poxvirus_B22R PF04395.12 OEU23291.1 - 0.06 12.9 0.1 0.06 12.9 0.1 2.9 2 2 0 2 2 2 0 Poxvirus B22R protein DUF2368 PF10166.9 OEU23291.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Macoilin PF09726.9 OEU23291.1 - 0.25 9.9 11.0 0.33 9.5 11.0 1.2 1 0 0 1 1 1 0 Macoilin family SepRS_C PF18006.1 OEU23292.1 - 0.00092 19.3 0.0 0.69 10.1 0.0 3.6 3 0 0 3 3 3 1 O-phosphoseryl-tRNA synthetase C-terminal domain YrbL-PhoP_reg PF10707.9 OEU23292.1 - 0.11 12.0 0.5 0.42 10.1 0.0 2.2 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL YjgF_endoribonc PF14588.6 OEU23294.1 - 0.0007 19.8 0.0 0.00098 19.3 0.0 1.2 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease DUF3915 PF13054.6 OEU23295.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3915 PF13054.6 OEU23296.1 - 0.061 13.3 13.6 0.098 12.6 0.0 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3915) DUF5539 PF17693.1 OEU23296.1 - 0.18 11.4 1.0 0.35 10.5 0.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5539) PLAC8 PF04749.17 OEU23297.1 - 2e-15 57.6 18.8 3.9e-15 56.7 18.8 1.5 1 0 0 1 1 1 1 PLAC8 family NST1 PF13945.6 OEU23297.1 - 2.9 8.0 4.9 5.2 7.1 4.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator SDA1 PF05285.12 OEU23298.1 - 2.5 7.4 10.0 3.5 6.9 10.0 1.2 1 0 0 1 1 1 0 SDA1 Phage_tail_X PF05489.12 OEU23299.1 - 0.25 11.1 1.7 11 5.8 0.1 2.6 2 0 0 2 2 2 0 Phage Tail Protein X DUF3134 PF11332.8 OEU23300.1 - 3.8 7.9 7.2 22 5.4 7.2 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Myb_DNA-binding PF00249.31 OEU23303.1 - 1.2e-05 25.3 0.6 4.1e-05 23.7 0.6 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU23303.1 - 0.12 12.7 3.3 0.085 13.1 0.7 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2749 PF10907.8 OEU23303.1 - 0.75 10.0 5.3 0.23 11.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) PcF PF09461.10 OEU23304.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Phytotoxin PcF protein DUF3086 PF11285.8 OEU23304.1 - 0.085 12.0 3.1 0.15 11.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Sulfotransfer_2 PF03567.14 OEU23305.1 - 0.0033 17.4 0.4 0.023 14.6 0.4 2.3 1 1 0 1 1 1 1 Sulfotransferase family DUF799 PF05643.11 OEU23306.1 - 0.033 13.8 0.2 0.074 12.6 0.2 1.6 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) YbgT_YccB PF08173.11 OEU23306.1 - 0.5 10.5 3.1 2.9 8.1 0.3 2.4 2 0 0 2 2 2 0 Membrane bound YbgT-like protein DUF2489 PF10675.9 OEU23306.1 - 1.8 8.5 4.7 0.24 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DHHC PF01529.20 OEU23306.1 - 4.5 7.4 9.6 3.1 7.9 1.2 3.5 4 0 0 4 4 4 0 DHHC palmitoyltransferase LRR_4 PF12799.7 OEU23307.1 - 0.019 15.4 1.1 0.019 15.4 1.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OEU23307.1 - 0.056 13.5 9.5 0.99 9.6 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Fucokinase PF07959.12 OEU23308.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase Amino_oxidase PF01593.24 OEU23309.1 - 3.4e-06 26.6 0.5 3.6e-06 26.6 0.5 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ca_hom_mod PF14798.6 OEU23309.1 - 0.049 12.7 0.2 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 Calcium homeostasis modulator Ank_3 PF13606.6 OEU23310.1 - 0.0047 17.3 0.6 2.2 9.1 0.3 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OEU23310.1 - 0.014 16.0 0.0 4.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU23310.1 - 0.019 15.5 0.0 4.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) LRRC37AB_C PF14914.6 OEU23310.1 - 0.022 14.7 0.3 0.03 14.2 0.3 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Ank PF00023.30 OEU23310.1 - 0.81 10.2 3.6 4.8 7.8 0.1 3.0 2 1 0 2 2 2 0 Ankyrin repeat Aminotran_1_2 PF00155.21 OEU23311.1 - 1.2e-41 143.1 0.0 1.5e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OEU23311.1 - 1.3e-05 24.2 0.1 1.7e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 OEU23311.1 - 0.0029 16.9 0.1 0.0042 16.4 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 OEU23311.1 - 0.023 13.4 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Mon1 PF03164.14 OEU23313.1 - 0.001 18.2 1.6 0.0015 17.7 0.4 1.6 1 1 1 2 2 2 1 Trafficking protein Mon1 Pex14_N PF04695.13 OEU23314.1 - 0.021 15.5 0.1 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF872 PF05915.12 OEU23314.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Asn_synthase PF00733.21 OEU23315.1 - 1.4e-17 64.4 0.0 5.2e-16 59.3 0.0 2.0 1 1 1 2 2 2 1 Asparagine synthase Rnf-Nqr PF02508.14 OEU23315.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Med3 PF11593.8 OEU23315.1 - 1.3 8.1 6.7 1.9 7.6 6.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SRP19 PF01922.17 OEU23316.1 - 9.3e-21 74.6 0.2 3.3e-20 72.8 0.2 1.9 1 1 0 1 1 1 1 SRP19 protein PT PF04886.12 OEU23317.1 - 4.6e-12 45.3 28.4 1.3e-07 31.0 12.9 2.4 1 1 1 2 2 2 2 PT repeat DUF4106 PF13388.6 OEU23317.1 - 1.8 7.7 11.7 2.3 7.4 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Glycoprotein_G PF00802.19 OEU23317.1 - 2.4 7.4 14.7 3.8 6.8 14.7 1.4 1 1 0 1 1 1 0 Pneumovirus attachment glycoprotein G NolV PF06635.12 OEU23318.1 - 0.2 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein NolV FAD_binding_3 PF01494.19 OEU23319.1 - 3.3e-19 69.3 4.1 2e-12 47.0 0.3 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OEU23319.1 - 7.4e-07 28.7 0.0 1.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OEU23319.1 - 1.3e-05 25.0 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OEU23319.1 - 1.5e-05 25.4 0.1 5.7e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OEU23319.1 - 3.2e-05 24.1 0.4 0.00013 22.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OEU23319.1 - 8.2e-05 22.0 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OEU23319.1 - 0.0003 20.0 1.6 0.0038 16.4 0.9 2.2 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 OEU23319.1 - 0.0056 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 OEU23319.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 OEU23319.1 - 0.011 14.7 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase YscJ_FliF_C PF08345.11 OEU23319.1 - 0.11 12.8 5.5 0.23 11.8 1.1 3.1 1 1 2 3 3 3 0 Flagellar M-ring protein C-terminal Androgen_recep PF02166.16 OEU23320.1 - 3.7 6.3 13.8 6.8 5.4 13.8 1.4 1 0 0 1 1 1 0 Androgen receptor FXR_C1 PF16096.5 OEU23321.1 - 0.71 10.1 9.7 0.062 13.5 3.7 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 UL45 PF05473.12 OEU23322.1 - 0.0046 16.6 2.0 0.007 16.0 2.0 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like MoeA_N PF03453.17 OEU23322.1 - 0.022 14.5 0.9 0.03 14.1 0.9 1.2 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) Stevor PF17410.2 OEU23322.1 - 0.21 11.1 1.2 0.29 10.6 1.2 1.4 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame Mito_fiss_reg PF05308.11 OEU23322.1 - 0.32 11.1 3.4 0.4 10.7 3.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-RING_2 PF13639.6 OEU23324.1 - 2.8e-15 56.4 8.0 3.1e-15 56.2 8.0 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OEU23324.1 - 4.3e-11 42.3 5.4 4.3e-11 42.3 5.4 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OEU23324.1 - 4.6e-10 39.2 6.3 5.9e-10 38.8 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OEU23324.1 - 1.5e-08 34.4 7.7 1.8e-08 34.1 7.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OEU23324.1 - 2e-08 34.4 10.5 4.9e-08 33.1 10.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU23324.1 - 3.1e-08 33.5 5.0 4.1e-08 33.1 5.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OEU23324.1 - 3.6e-08 33.2 6.0 4.1e-08 33.1 6.0 1.1 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OEU23324.1 - 9.2e-07 28.6 5.8 1.4e-06 28.0 5.8 1.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OEU23324.1 - 2.4e-05 24.1 5.3 3.2e-05 23.7 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OEU23324.1 - 0.00014 21.9 4.4 0.00022 21.3 4.4 1.3 1 1 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 OEU23324.1 - 0.0011 19.0 5.8 0.0019 18.2 5.8 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 OEU23324.1 - 0.0016 18.3 5.2 0.0035 17.2 5.2 1.6 1 1 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 OEU23324.1 - 0.0083 16.2 0.6 0.0083 16.2 0.6 1.5 1 1 0 1 1 1 1 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 OEU23324.1 - 0.015 14.9 8.1 0.029 14.0 8.1 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OEU23324.1 - 0.022 14.6 4.1 0.026 14.3 4.1 1.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OEU23324.1 - 0.2 11.9 8.3 1.3 9.3 8.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 OEU23324.1 - 0.3 11.0 5.8 0.34 10.8 5.8 1.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OEU23324.1 - 0.36 11.0 7.2 1.5 9.0 7.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 OEU23324.1 - 9.9 6.3 13.0 20 5.3 12.1 2.1 1 1 0 1 1 1 0 Zinc-finger Rb_C PF08934.10 OEU23325.1 - 0.012 15.5 1.0 0.025 14.4 1.0 1.5 1 0 0 1 1 1 0 Rb C-terminal domain SRP-alpha_N PF04086.13 OEU23325.1 - 0.84 9.5 14.2 1.2 9.0 14.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 OEU23325.1 - 2.9 6.6 4.5 3.4 6.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin Peripla_BP_4 PF13407.6 OEU23326.1 - 0.028 14.0 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Patatin PF01734.22 OEU23326.1 - 0.12 12.5 0.0 0.65 10.1 0.0 2.1 1 1 0 1 1 1 0 Patatin-like phospholipase DUF4376 PF14301.6 OEU23327.1 - 0.044 14.1 1.5 0.15 12.4 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) Clr2 PF10383.9 OEU23328.1 - 0.047 14.5 1.2 0.09 13.6 1.2 1.4 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 CHASE3 PF05227.13 OEU23328.1 - 0.054 13.4 4.6 1 9.3 0.0 2.5 2 0 0 2 2 2 0 CHASE3 domain DZR PF12773.7 OEU23328.1 - 0.12 12.4 1.8 0.28 11.2 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU23328.1 - 0.13 12.0 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S2 PF00318.20 OEU23328.1 - 2 7.6 6.4 0.12 11.5 0.4 2.2 3 0 0 3 3 3 0 Ribosomal protein S2 DUF3638 PF12340.8 OEU23329.1 - 2.3e-59 200.5 0.0 5.3e-59 199.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OEU23329.1 - 1.6e-10 40.2 0.0 3.5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) TFIIF_alpha PF05793.12 OEU23330.1 - 0.0021 16.7 3.3 0.0028 16.3 3.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tic22 PF04278.12 OEU23331.1 - 0.00048 19.6 2.8 0.00058 19.3 2.8 1.3 1 1 0 1 1 1 1 Tic22-like family DUF4834 PF16118.5 OEU23331.1 - 0.085 13.8 0.2 0.13 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 OEU23331.1 - 0.11 10.9 1.1 0.12 10.7 1.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ATP19 PF11022.8 OEU23331.1 - 1.2 9.6 4.1 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase subunit K RXLR PF16810.5 OEU23332.1 - 0.24 11.9 4.2 1.3 9.4 4.2 2.2 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity CCDC71L PF15374.6 OEU23332.1 - 5 6.3 7.5 0.57 9.4 0.1 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 71L Bestrophin PF01062.21 OEU23334.1 - 0.00056 19.4 0.1 0.00061 19.3 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1325 PF07039.11 OEU23335.1 - 7.3e-24 84.3 0.0 1.4e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain SAP30_Sin3_bdg PF13867.6 OEU23335.1 - 1.6e-09 37.9 0.0 3.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 ASFV_J13L PF05568.11 OEU23336.1 - 0.075 12.8 3.4 0.077 12.8 3.4 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein TPPK_C PF12555.8 OEU23336.1 - 0.16 12.1 7.6 0.24 11.5 7.6 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Fusion_gly PF00523.18 OEU23336.1 - 1.1 7.5 6.7 1.1 7.4 6.7 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Alpha_E2_glycop PF00943.19 OEU23336.1 - 1.1 7.9 4.0 1.1 7.9 4.0 1.0 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Ferlin_C PF16165.5 OEU23336.1 - 1.1 9.2 3.6 1.2 9.1 3.6 1.1 1 0 0 1 1 1 0 Ferlin C-terminus Mucin PF01456.17 OEU23337.1 - 0.06 13.3 10.9 0.13 12.2 10.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2721 PF11026.8 OEU23337.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF3439 PF11921.8 OEU23337.1 - 0.18 11.8 10.7 0.42 10.6 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RNF111_N PF15303.6 OEU23337.1 - 0.88 9.3 12.2 0.088 12.6 3.5 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus NST1 PF13945.6 OEU23337.1 - 2 8.5 11.0 1.1 9.3 0.9 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator SR-25 PF10500.9 OEU23337.1 - 2.1 7.9 6.2 0.54 9.8 1.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 OEU23337.1 - 7.1 4.6 11.4 0.17 9.9 4.8 1.6 1 1 0 2 2 2 0 Sporozoite P67 surface antigen 2-oxoacid_dh PF00198.23 OEU23338.1 - 0.02 14.3 2.1 0.021 14.2 1.4 1.3 1 1 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) PAS_2 PF08446.11 OEU23338.1 - 0.028 15.1 0.3 0.046 14.4 0.3 1.4 1 0 0 1 1 1 0 PAS fold Arm_APC_u3 PF16629.5 OEU23339.1 - 0.0017 18.0 2.8 0.0022 17.6 2.8 1.2 1 0 0 1 1 1 1 Armadillo-associated region on APC SUIM_assoc PF16619.5 OEU23339.1 - 0.013 15.6 8.5 0.45 10.6 0.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FG-GAP PF01839.23 OEU23340.1 - 1.1e-05 25.5 2.2 0.038 14.1 0.1 3.6 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.6 OEU23340.1 - 0.013 16.1 18.7 0.015 15.8 0.6 4.8 5 1 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RRN3 PF05327.11 OEU23341.1 - 0.29 9.6 9.8 0.38 9.2 9.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OEU23341.1 - 0.38 10.6 10.2 0.73 9.7 10.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 OEU23341.1 - 0.97 7.6 12.7 1.3 7.2 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OEU23341.1 - 1.2 8.5 15.8 1.6 8.1 15.8 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 OEU23341.1 - 2.3 6.7 22.7 3.3 6.2 22.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 OEU23341.1 - 4 6.7 17.0 5.5 6.2 17.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OEU23341.1 - 6.3 4.9 16.7 8.4 4.5 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family PPR_2 PF13041.6 OEU23342.1 - 1.8e-50 168.9 16.2 8.2e-12 45.1 0.0 11.3 8 3 2 10 10 10 9 PPR repeat family PPR_1 PF12854.7 OEU23342.1 - 1.3e-49 165.6 18.5 1.4e-07 31.1 0.0 13.9 14 1 0 14 14 14 9 PPR repeat PPR PF01535.20 OEU23342.1 - 2.7e-35 118.2 33.9 4.4e-07 29.7 0.0 16.2 14 4 0 14 14 14 5 PPR repeat PPR_3 PF13812.6 OEU23342.1 - 2.1e-32 111.0 11.8 6.2e-08 32.6 0.0 8.2 7 2 1 8 8 8 6 Pentatricopeptide repeat domain PPR_long PF17177.4 OEU23342.1 - 9.9e-14 51.2 1.6 0.0002 20.8 0.0 5.3 4 1 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP PMBR PF09373.10 OEU23342.1 - 0.76 10.0 4.0 40 4.6 0.0 4.2 4 0 0 4 4 4 0 Pseudomurein-binding repeat Glyco_transf_17 PF04724.13 OEU23343.1 - 0.0026 16.9 0.4 0.012 14.7 0.4 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF2951 PF11166.8 OEU23343.1 - 1.3 9.3 11.5 7.4 6.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) CPSF100_C PF13299.6 OEU23343.1 - 2.6 8.2 12.6 1.5 9.0 3.8 3.2 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal FKS1_dom1 PF14288.6 OEU23343.1 - 4.9 7.5 10.7 0.23 11.8 3.1 2.7 2 1 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Gly_transf_sug PF04488.15 OEU23344.1 - 2.1e-05 25.1 0.3 2.1e-05 25.1 0.3 2.3 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OEU23344.1 - 0.0004 19.8 0.8 0.00051 19.5 0.1 1.6 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain DUF1435 PF07256.12 OEU23344.1 - 0.18 11.9 0.1 2.7 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) PH PF00169.29 OEU23346.1 - 8.4e-19 68.0 0.1 1.5e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 OEU23346.1 - 3.3e-05 23.9 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 OEU23346.1 - 0.0017 18.2 0.1 0.0017 18.2 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 OEU23346.1 - 0.0018 18.5 0.2 0.0046 17.2 0.1 1.8 1 1 1 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OEU23346.1 - 0.0037 17.7 6.9 0.0068 16.8 2.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain SUIM_assoc PF16619.5 OEU23346.1 - 0.014 15.4 1.0 0.014 15.4 1.0 6.8 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SOG2 PF10428.9 OEU23346.1 - 0.12 11.5 20.8 0.18 11.0 20.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PH_6 PF15406.6 OEU23346.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain GREB1 PF15782.5 OEU23346.1 - 3.4 4.7 23.6 5.5 4.0 23.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_33 PF13671.6 OEU23347.1 - 0.003 17.7 0.0 0.035 14.3 0.0 2.6 2 1 1 3 3 3 1 AAA domain 2OG-FeII_Oxy_3 PF13640.6 OEU23348.1 - 4.4e-12 46.7 0.2 1.8e-11 44.8 0.2 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OEU23348.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sulfotransfer_3 PF13469.6 OEU23349.1 - 4.7e-06 27.1 0.0 8.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 OEU23349.1 - 0.0026 17.6 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain HNH_3 PF13392.6 OEU23349.1 - 0.011 15.5 0.5 0.042 13.6 0.5 2.0 1 0 0 1 1 1 0 HNH endonuclease Amidohydro_2 PF04909.14 OEU23350.1 - 3.2e-24 86.2 0.0 3.9e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase THF_DHG_CYH PF00763.23 OEU23350.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain MS_channel PF00924.18 OEU23351.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel SLATT_5 PF18160.1 OEU23351.1 - 0.00011 21.6 0.4 0.00036 19.9 0.0 2.0 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 EF-hand_8 PF13833.6 OEU23351.1 - 0.0068 16.2 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair SLATT_4 PF18186.1 OEU23351.1 - 0.16 11.6 1.5 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Methyltransf_25 PF13649.6 OEU23352.1 - 1.6e-19 70.4 0.0 3.3e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OEU23352.1 - 3.1e-19 69.4 0.0 5.1e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OEU23352.1 - 2.2e-15 56.9 0.0 3.9e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OEU23352.1 - 9.6e-14 51.9 0.0 2.3e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OEU23352.1 - 1.3e-12 47.6 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 OEU23352.1 - 1.5e-12 47.6 0.0 2.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OEU23352.1 - 5.5e-07 29.2 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OEU23352.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OEU23352.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OEU23352.1 - 0.00034 20.3 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 OEU23352.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 OEU23352.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 OEU23352.1 - 0.0028 17.6 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase CheR PF01739.18 OEU23352.1 - 0.0037 16.8 0.0 0.076 12.5 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 OEU23352.1 - 0.0076 15.7 0.1 0.64 9.5 0.0 2.6 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.13 OEU23352.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 OEU23352.1 - 0.012 14.1 0.0 0.023 13.3 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 OEU23352.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 OEU23352.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB AdoMet_MTase PF07757.13 OEU23352.1 - 0.073 13.4 0.3 0.22 11.9 0.2 1.9 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 OEU23352.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Presenilin PF01080.17 OEU23353.1 - 0.11 11.2 2.3 0.14 10.9 2.3 1.1 1 0 0 1 1 1 0 Presenilin CFIA_Pcf11 PF11526.8 OEU23353.1 - 0.61 10.6 15.0 0.21 12.1 1.2 2.1 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 NFACT-R_1 PF05670.13 OEU23354.1 - 4.8e-40 136.6 1.7 1.1e-39 135.5 0.1 1.9 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF4962 PF16332.5 OEU23354.1 - 0.06 11.8 5.8 0.075 11.5 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) DUF3597 PF12200.8 OEU23355.1 - 1.7 9.2 4.2 0.85 10.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) SOG2 PF10428.9 OEU23355.1 - 1.9 7.6 26.6 0.083 12.1 10.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SPX PF03105.19 OEU23355.1 - 4.5 7.1 16.2 9 6.1 1.2 2.2 2 0 0 2 2 2 0 SPX domain PPDK_N PF01326.19 OEU23359.1 - 1.4e-56 192.2 0.1 2.1e-56 191.6 0.1 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OEU23359.1 - 5.7e-16 58.0 0.1 1.3e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain ADP_ribosyl_GH PF03747.14 OEU23361.1 - 0.26 11.0 1.3 0.4 10.4 0.5 1.6 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Glt_symporter PF03616.14 OEU23361.1 - 0.37 9.4 0.1 0.48 9.1 0.1 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter EMC3_TMCO1 PF01956.16 OEU23361.1 - 0.59 9.8 2.7 1.2 8.8 2.7 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Atg14 PF10186.9 OEU23361.1 - 0.79 8.7 9.6 1 8.4 9.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAF-1_p150 PF11600.8 OEU23361.1 - 0.8 9.4 34.0 0.2 11.3 29.5 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SID-1_RNA_chan PF13965.6 OEU23361.1 - 1.3 7.4 2.4 1.7 7.0 2.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 COX16 PF14138.6 OEU23361.1 - 1.3 9.5 10.8 0.089 13.3 5.4 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 bHLH-MYC_N PF14215.6 OEU23361.1 - 2.4 8.4 0.0 2.4 8.4 0.0 2.5 2 1 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal SOBP PF15279.6 OEU23361.1 - 2.5 8.7 19.6 0.38 11.3 15.2 1.6 2 0 0 2 2 2 0 Sine oculis-binding protein NPR3 PF03666.13 OEU23361.1 - 4.1 6.1 16.3 0.26 10.1 6.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 OEU23361.1 - 7.1 3.6 7.7 8.6 3.3 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AGH PF17558.2 OEU23362.1 - 0.21 11.8 0.2 0.64 10.2 0.1 1.9 3 0 0 3 3 3 0 Androgenic gland hormone TIP41 PF04176.13 OEU23363.1 - 0.021 14.3 0.7 0.032 13.7 0.7 1.3 1 0 0 1 1 1 0 TIP41-like family Sacchrp_dh_NADP PF03435.18 OEU23365.1 - 2.4e-06 27.8 0.1 2.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF4113 PF13438.6 OEU23365.1 - 0.17 12.0 0.0 8.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) TFIIA PF03153.13 OEU23366.1 - 0.008 16.2 3.4 0.008 16.2 3.4 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Glyco_transf_8 PF01501.20 OEU23366.1 - 0.03 13.9 11.6 0.3 10.6 1.2 3.8 3 1 1 4 4 4 0 Glycosyl transferase family 8 Tachykinin PF02202.16 OEU23366.1 - 0.037 13.9 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Tachykinin family Mito_carr PF00153.27 OEU23366.1 - 0.27 11.2 2.1 0.7 9.8 2.1 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein MAP17 PF15807.5 OEU23367.1 - 0.045 14.0 1.5 0.067 13.4 0.1 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Rrp44_S1 PF17215.3 OEU23368.1 - 0.079 12.9 0.6 0.11 12.5 0.6 1.2 1 0 0 1 1 1 0 S1 domain Membralin PF09746.9 OEU23369.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein TMEM154 PF15102.6 OEU23370.1 - 0.001 19.0 0.8 0.001 19.0 0.8 4.7 4 1 0 5 5 5 1 TMEM154 protein family Orf78 PF06024.12 OEU23370.1 - 0.025 14.9 0.1 0.025 14.9 0.1 5.4 5 2 0 5 5 5 0 Orf78 (ac78) DUF305 PF03713.13 OEU23370.1 - 0.069 13.3 12.0 0.038 14.1 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF305) DUF3357 PF11837.8 OEU23370.1 - 0.12 12.8 3.0 0.7 10.4 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) IMUP PF15761.5 OEU23370.1 - 0.47 11.2 12.6 0.46 11.2 4.7 2.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 OEU23370.1 - 0.96 9.0 34.3 0.02 14.5 1.7 3.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein LBP_BPI_CETP PF01273.25 OEU23371.1 - 3.8e-07 29.9 0.6 3.8e-07 29.9 0.6 2.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain PqiA PF04403.13 OEU23371.1 - 0.072 12.9 4.6 7.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Paraquat-inducible protein A Amidase_5 PF05382.13 OEU23371.1 - 0.15 12.0 0.9 0.64 9.9 0.5 2.3 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase Arrestin_N PF00339.29 OEU23372.1 - 0.0016 18.5 0.1 0.0074 16.3 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain OATP PF03137.20 OEU23373.1 - 0.22 9.8 0.4 0.37 9.0 0.4 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATP-synt_E PF05680.12 OEU23373.1 - 0.42 11.0 5.2 4.9 7.6 5.1 2.5 2 0 0 2 2 2 0 ATP synthase E chain CLN3 PF02487.17 OEU23373.1 - 1.3 8.0 2.8 2.5 7.1 2.8 1.4 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 OEU23373.1 - 1.7 8.4 12.5 0.12 12.2 3.5 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 OEU23374.1 - 0.41 10.3 8.3 6.1 6.5 8.4 2.0 1 1 0 1 1 1 0 FAM176 family rve PF00665.26 OEU23378.1 - 1.1e-05 25.6 0.0 0.00024 21.3 0.0 2.3 1 1 1 2 2 2 2 Integrase core domain Retrotran_gag_2 PF14223.6 OEU23379.1 - 0.029 14.0 5.7 0.12 12.0 0.1 2.5 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type MnmE_helical PF12631.7 OEU23379.1 - 0.034 14.3 1.0 0.064 13.4 1.0 1.4 1 0 0 1 1 1 0 MnmE helical domain DUF1104 PF06518.11 OEU23379.1 - 8.2 6.9 12.5 4.9 7.6 4.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) BTB PF00651.31 OEU23380.1 - 4.4e-06 26.9 0.0 7.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HCO3_cotransp PF00955.21 OEU23381.1 - 5.6e-85 286.1 0.6 9.6e-84 282.0 0.6 2.1 1 1 0 1 1 1 1 HCO3- transporter family Nop14 PF04147.12 OEU23381.1 - 0.076 11.2 22.7 0.1 10.8 22.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2796 PF10986.8 OEU23381.1 - 3 7.8 13.7 5 7.1 13.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) CDC45 PF02724.14 OEU23381.1 - 4 5.6 17.8 5.5 5.2 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_17 PF04724.13 OEU23382.1 - 9.5e-10 38.0 0.2 1.5e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Sulfotransfer_4 PF17784.1 OEU23383.1 - 1.5e-05 24.9 0.2 5.6e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OEU23383.1 - 0.00021 21.7 2.6 1.6 9.1 0.0 3.3 1 1 1 3 3 3 2 Sulfotransferase family EF-hand_5 PF13202.6 OEU23384.1 - 9.8e-07 28.0 0.1 3.8e-06 26.1 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OEU23384.1 - 6.3e-06 25.7 1.2 0.00011 21.9 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OEU23384.1 - 1.7e-05 24.0 4.1 2e-05 23.8 0.4 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OEU23384.1 - 7.7e-05 22.5 0.3 7.7e-05 22.5 0.3 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 OEU23384.1 - 0.0021 18.5 1.0 0.0078 16.6 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain pair DUF4574 PF15141.6 OEU23384.1 - 0.38 10.7 1.3 1 9.3 1.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 BUD22 PF09073.10 OEU23385.1 - 0.21 10.9 16.7 0.023 14.1 11.0 2.1 2 1 0 2 2 2 0 BUD22 NOA36 PF06524.12 OEU23385.1 - 3.4 6.9 20.3 0.72 9.1 5.3 3.2 3 0 0 3 3 3 0 NOA36 protein HYR PF02494.16 OEU23386.1 - 0.49 10.8 5.5 4 7.8 0.2 2.8 2 0 0 2 2 2 0 HYR domain FAM163 PF15069.6 OEU23386.1 - 4.7 7.6 10.2 0.95 9.9 0.1 2.6 2 1 0 2 2 2 0 FAM163 family Fasciclin PF02469.22 OEU23387.1 - 2.3e-16 60.2 0.0 3.6e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF948 PF06103.11 OEU23388.1 - 0.044 14.0 1.4 6.3 7.1 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2207 PF09972.9 OEU23388.1 - 0.23 10.2 5.1 1.1 8.0 3.7 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2649 PF10854.8 OEU23389.1 - 0.058 13.7 0.3 0.058 13.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) SWIM PF04434.17 OEU23390.1 - 2.4e-07 30.3 0.7 4.6e-07 29.4 0.7 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-MYND PF01753.18 OEU23391.1 - 2.3e-05 24.4 16.5 3.9e-05 23.7 16.5 1.4 1 0 0 1 1 1 1 MYND finger STELLO PF03385.17 OEU23393.1 - 4.7e-07 29.0 0.3 4.7e-07 29.0 0.3 3.5 3 0 0 3 3 3 2 STELLO glycosyltransferases CPSF100_C PF13299.6 OEU23393.1 - 1 9.5 10.5 0.31 11.2 1.6 3.8 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 OEU23394.1 - 0.12 11.9 9.3 0.17 11.5 9.3 1.1 1 0 0 1 1 1 0 Spt20 family CCDC24 PF15669.5 OEU23394.1 - 0.25 11.2 5.3 0.34 10.7 5.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF720 PF05302.11 OEU23394.1 - 0.36 10.7 9.0 0.57 10.0 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF2142 PF09913.9 OEU23394.1 - 0.38 9.6 0.6 0.46 9.3 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SUIM_assoc PF16619.5 OEU23394.1 - 0.64 10.1 14.4 0.74 9.9 1.7 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 OEU23394.1 - 4 6.1 6.9 4.5 5.9 6.9 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OEU23394.1 - 5.5 5.4 10.6 6 5.3 10.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3871 PF12987.7 OEU23395.1 - 0.067 12.0 0.1 0.091 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) NIL PF09383.10 OEU23395.1 - 0.086 12.7 0.0 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 NIL domain RVT_1 PF00078.27 OEU23396.1 - 0.00029 20.4 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pneumo_phosprot PF02478.16 OEU23396.1 - 0.86 9.1 6.0 1.8 8.1 6.0 1.4 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Cnd2 PF05786.14 OEU23398.1 - 3e-85 287.5 49.7 7e-79 266.4 20.2 4.8 2 2 1 3 3 3 2 Condensin complex subunit 2 CNDH2_N PF06278.11 OEU23398.1 - 0.00011 22.3 0.0 0.00011 22.3 0.0 3.7 5 0 0 5 5 5 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal PPO1_KFDV PF12143.8 OEU23399.1 - 0.054 13.6 0.4 0.88 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF_B2219) zf-RING_2 PF13639.6 OEU23400.1 - 2.7e-07 30.8 5.0 4e-06 27.1 0.8 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OEU23400.1 - 2.3e-05 24.0 4.0 2.5e-05 23.9 1.8 2.0 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 OEU23400.1 - 4.8e-05 23.4 1.3 0.00025 21.2 0.6 2.1 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 OEU23400.1 - 0.0024 17.7 3.7 0.019 14.8 0.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OEU23400.1 - 0.0044 17.0 5.0 0.012 15.6 0.3 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 OEU23400.1 - 0.035 14.4 0.9 0.035 14.4 0.9 2.9 3 1 0 3 3 3 0 RING-H2 zinc finger domain Tmpp129 PF10272.9 OEU23400.1 - 0.038 13.3 2.9 0.075 12.3 0.2 2.1 2 0 0 2 2 2 0 Putative transmembrane protein precursor Zn_ribbon_17 PF17120.5 OEU23400.1 - 0.073 12.7 1.3 0.19 11.3 1.3 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_4 PF07975.12 OEU23400.1 - 0.083 13.1 2.1 5.7 7.3 0.2 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-ANAPC11 PF12861.7 OEU23400.1 - 0.31 11.1 2.2 1.1 9.4 0.4 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OEU23400.1 - 0.32 10.9 6.3 0.6 10.1 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 OEU23400.1 - 0.33 10.8 4.6 8 6.4 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OEU23400.1 - 0.42 10.5 10.8 0.11 12.4 2.1 3.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DAGAT PF03982.13 OEU23401.1 - 1.6e-40 138.9 15.3 1.7e-18 66.6 0.1 5.7 2 2 1 3 3 3 3 Diacylglycerol acyltransferase CLN3 PF02487.17 OEU23401.1 - 0.0038 16.3 1.5 0.42 9.6 0.3 2.2 2 0 0 2 2 2 2 CLN3 protein SpoIIIAH PF12685.7 OEU23401.1 - 0.013 15.4 8.0 0.19 11.6 0.7 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 OEU23401.1 - 0.014 15.8 2.5 0.62 10.5 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase III RPC4 Serinc PF03348.15 OEU23401.1 - 0.026 13.5 1.7 0.078 11.9 0.0 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4228 PF14009.6 OEU23401.1 - 0.062 13.7 3.8 2.9 8.2 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) TOM13 PF08219.11 OEU23401.1 - 0.37 10.8 0.0 0.37 10.8 0.0 2.5 3 0 0 3 3 2 0 Outer membrane protein TOM13 Tim54 PF11711.8 OEU23401.1 - 1.1 7.9 11.0 0.15 10.9 2.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 OEU23401.1 - 2.6 8.0 8.7 6.3 6.7 0.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A TMEM51 PF15345.6 OEU23401.1 - 2.6 7.8 6.2 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Connexin PF00029.19 OEU23401.1 - 2.8 7.6 4.9 2.4 7.9 0.2 2.3 2 0 0 2 2 2 0 Connexin TRM13 PF05206.14 OEU23401.1 - 4 6.9 6.4 5.2 6.5 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase TRM13 CPSF100_C PF13299.6 OEU23401.1 - 5.6 7.1 10.8 11 6.2 3.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-RING_2 PF13639.6 OEU23402.1 - 1.4e-05 25.3 5.9 0.00021 21.5 1.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OEU23402.1 - 0.00035 20.3 1.9 0.00088 19.0 1.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger DUF4713 PF15831.5 OEU23402.1 - 0.0074 16.7 4.0 0.016 15.6 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) FANCL_C PF11793.8 OEU23402.1 - 0.0077 16.4 0.6 0.0077 16.4 0.6 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OEU23402.1 - 0.0081 16.0 5.2 0.043 13.7 1.1 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tetraspanin PF00335.20 OEU23402.1 - 0.01 15.6 5.8 0.027 14.2 5.9 1.6 1 1 0 1 1 1 0 Tetraspanin family zf-C3HC4 PF00097.25 OEU23402.1 - 0.013 15.3 1.5 0.013 15.3 1.5 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BUD22 PF09073.10 OEU23402.1 - 0.019 14.3 15.4 0.029 13.7 15.4 1.2 1 0 0 1 1 1 0 BUD22 zf-rbx1 PF12678.7 OEU23402.1 - 0.04 14.2 5.8 0.26 11.6 1.7 3.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OEU23402.1 - 0.081 13.0 1.5 0.28 11.2 0.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Apt1 PF10351.9 OEU23402.1 - 0.69 8.7 17.7 1.8 7.4 2.3 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain POM121 PF15229.6 OEU23402.1 - 0.83 9.3 15.8 0.18 11.5 6.5 2.5 2 0 0 2 2 2 0 POM121 family Acyltransferase PF01553.21 OEU23404.1 - 2.7e-07 30.3 0.0 5.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SOG2 PF10428.9 OEU23404.1 - 0.018 14.3 10.2 0.022 14.0 10.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 OEU23404.1 - 0.25 10.2 5.8 0.37 9.6 5.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 OEU23404.1 - 3 7.7 6.6 5 7.0 6.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Alpha-2-MRAP_N PF06400.11 OEU23405.1 - 0.022 14.8 0.3 0.03 14.3 0.3 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain TLD PF07534.16 OEU23406.1 - 0.00038 20.7 8.1 0.0045 17.2 3.5 4.1 2 1 0 2 2 2 1 TLD Flavodoxin_3 PF12641.7 OEU23407.1 - 0.014 15.1 0.1 4.1 7.1 0.0 2.4 1 1 0 2 2 2 0 Flavodoxin domain DUF4790 PF16037.5 OEU23407.1 - 0.057 13.9 0.9 0.14 12.7 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) GED PF02212.18 OEU23407.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF758 PF05527.11 OEU23407.1 - 0.13 12.2 0.4 0.74 9.8 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF758) PT PF04886.12 OEU23408.1 - 1.4e-08 34.1 11.2 0.00014 21.3 2.0 2.3 1 1 1 2 2 2 2 PT repeat PsbI PF02532.14 OEU23408.1 - 2.6 8.1 5.1 21 5.1 0.4 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) PT PF04886.12 OEU23409.1 - 1.2e-12 47.2 54.4 5.6 6.6 25.6 4.6 1 1 1 2 2 2 1 PT repeat PT PF04886.12 OEU23410.1 - 5.1e-07 29.1 30.1 5.8 6.6 30.1 3.1 1 1 0 1 1 1 1 PT repeat DUF1995 PF09353.10 OEU23411.1 - 5.6e-37 127.7 0.0 6.7e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) TisB_toxin PF13939.6 OEU23412.1 - 0.15 11.9 0.2 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system Aa_trans PF01490.18 OEU23413.1 - 1.2e-10 40.7 2.2 1.4e-10 40.5 2.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfzA PF14118.6 OEU23413.1 - 0.01 16.3 1.4 0.011 16.1 0.5 1.6 1 1 1 2 2 2 1 YfzA-like protein GAD-like PF08887.11 OEU23413.1 - 0.068 13.0 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 GAD-like domain AAA_16 PF13191.6 OEU23414.1 - 2.4e-06 28.0 0.0 5.4e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 OEU23414.1 - 6.5e-06 26.1 0.1 0.014 15.3 0.0 2.3 2 0 0 2 2 2 2 NTPase AAA PF00004.29 OEU23414.1 - 1.3e-05 25.6 0.0 2.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OEU23414.1 - 2.8e-05 23.7 0.0 7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 OEU23414.1 - 4.8e-05 23.2 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OEU23414.1 - 0.00013 22.2 0.1 0.00039 20.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OEU23414.1 - 0.00025 21.1 0.1 0.00092 19.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OEU23414.1 - 0.00031 21.3 0.0 0.00069 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OEU23414.1 - 0.0004 20.2 0.1 0.00088 19.1 0.0 1.6 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OEU23414.1 - 0.00066 19.0 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin TniB PF05621.11 OEU23414.1 - 0.00071 19.0 0.1 0.26 10.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 OEU23414.1 - 0.0018 18.8 0.2 0.0035 17.9 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 OEU23414.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OEU23414.1 - 0.0022 18.3 0.2 0.0056 17.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OEU23414.1 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain T2SSE PF00437.20 OEU23414.1 - 0.0033 16.5 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.19 OEU23414.1 - 0.0036 16.9 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OEU23414.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OEU23414.1 - 0.0098 15.9 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OEU23414.1 - 0.011 15.5 0.1 0.15 11.8 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 OEU23414.1 - 0.018 15.0 0.1 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OEU23414.1 - 0.02 15.2 0.1 0.045 14.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 OEU23414.1 - 0.024 14.1 0.1 0.066 12.7 0.0 1.7 1 1 1 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 OEU23414.1 - 0.025 13.8 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 OEU23414.1 - 0.029 13.3 0.1 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 OEU23414.1 - 0.035 13.9 0.8 0.11 12.3 0.5 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OEU23414.1 - 0.039 13.3 0.3 0.43 9.9 0.1 2.1 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 OEU23414.1 - 0.046 14.1 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DLIC PF05783.11 OEU23414.1 - 0.054 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_29 PF13555.6 OEU23414.1 - 0.058 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OEU23414.1 - 0.06 12.9 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OEU23414.1 - 0.061 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 OEU23414.1 - 0.1 11.8 0.2 0.19 10.9 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.20 OEU23414.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 OEU23414.1 - 0.16 12.5 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OEU23415.1 - 5.7e-39 133.8 8.0 1.1e-20 74.5 0.1 3.1 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OEU23415.1 - 5.2e-23 80.9 14.5 2.5e-21 75.5 5.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OEU23415.1 - 1.9e-11 43.8 2.3 8.4e-05 22.1 0.1 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OEU23415.1 - 1.5e-09 38.1 12.3 0.066 13.0 0.1 4.5 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU23415.1 - 8.4e-08 32.3 0.2 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 OEU23415.1 - 4.1e-07 30.1 0.2 0.014 15.3 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 OEU23415.1 - 1e-06 29.1 3.4 0.00053 20.3 0.2 3.5 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU23415.1 - 2.6e-06 27.9 0.2 0.06 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OEU23415.1 - 1.2e-05 24.9 0.0 0.23 11.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NB-ARC PF00931.22 OEU23415.1 - 4.3e-05 22.8 0.1 0.016 14.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 OEU23415.1 - 6.1e-05 23.2 0.4 0.42 10.8 0.0 3.0 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 OEU23415.1 - 7.1e-05 22.4 2.1 0.15 11.6 0.0 2.9 2 1 1 3 3 3 2 Ferrous iron transport protein B AAA_30 PF13604.6 OEU23415.1 - 7.5e-05 22.5 0.0 0.26 11.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OEU23415.1 - 0.0001 22.6 1.3 4 7.9 0.0 3.6 3 0 0 3 3 3 1 RNA helicase NTPase_1 PF03266.15 OEU23415.1 - 0.00013 21.9 0.1 0.81 9.6 0.0 3.4 3 0 0 3 3 3 2 NTPase AAA_28 PF13521.6 OEU23415.1 - 0.00015 22.1 0.1 0.71 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OEU23415.1 - 0.00032 20.7 4.1 0.16 12.1 0.3 3.1 2 1 1 3 3 3 2 50S ribosome-binding GTPase SRP54 PF00448.22 OEU23415.1 - 0.00051 19.7 0.1 0.29 10.7 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OEU23415.1 - 0.00052 19.8 5.5 0.11 12.2 0.0 4.2 5 1 1 6 6 5 1 AAA domain AAA PF00004.29 OEU23415.1 - 0.00066 20.1 0.0 2.6 8.5 0.0 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OEU23415.1 - 0.00077 19.1 0.5 0.57 9.7 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OEU23415.1 - 0.0019 18.8 0.6 1.3 9.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OEU23415.1 - 0.0023 18.0 0.2 0.76 9.8 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 OEU23415.1 - 0.0037 17.6 1.6 1 9.7 0.3 3.2 2 2 0 2 2 2 1 AAA domain T2SSE PF00437.20 OEU23415.1 - 0.0044 16.1 0.4 0.3 10.1 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_7 PF12775.7 OEU23415.1 - 0.0054 16.3 0.1 0.87 9.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MobB PF03205.14 OEU23415.1 - 0.0067 16.3 0.2 5.4 6.9 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DLIC PF05783.11 OEU23415.1 - 0.0075 15.1 0.8 0.23 10.2 0.2 2.3 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 OEU23415.1 - 0.011 16.3 19.4 0.19 12.2 0.1 3.7 3 1 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 OEU23415.1 - 0.012 15.7 6.3 1.1 9.2 0.0 3.6 3 1 0 3 3 3 0 Dynamin family Septin PF00735.18 OEU23415.1 - 0.015 14.6 0.6 0.31 10.3 0.1 2.5 2 0 0 2 2 2 0 Septin MeaB PF03308.16 OEU23415.1 - 0.032 13.2 0.0 0.37 9.7 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OEU23415.1 - 0.036 13.6 2.6 1.5 8.4 0.1 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 OEU23415.1 - 0.038 14.0 0.1 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 OEU23415.1 - 0.039 13.7 1.3 11 5.8 0.2 3.0 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 OEU23415.1 - 0.058 13.4 0.8 21 5.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OEU23415.1 - 0.059 13.5 0.6 7.5 6.7 0.4 3.2 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OEU23415.1 - 0.084 12.8 0.0 0.084 12.8 0.0 2.8 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 OEU23415.1 - 0.14 12.4 0.7 25 5.2 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NdhM PF10664.9 OEU23415.1 - 0.19 12.0 1.6 0.33 11.2 0.3 2.1 2 0 0 2 2 1 0 Cyanobacterial and plastid NDH-1 subunit M ATP_bind_1 PF03029.17 OEU23415.1 - 0.22 11.3 3.2 2.2 8.0 0.0 3.0 4 0 0 4 4 2 0 Conserved hypothetical ATP binding protein DUF4878 PF12870.7 OEU23415.1 - 0.25 11.7 6.2 0.2 12.0 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) DUF285 PF03382.14 OEU23418.1 - 3.3e-52 175.3 20.1 4e-28 97.6 8.0 2.5 2 1 1 3 3 3 2 Mycoplasma protein of unknown function, DUF285 C2 PF00168.30 OEU23419.1 - 3.1e-19 69.2 0.1 4e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 C2 domain DUF1997 PF09366.10 OEU23420.1 - 3.3e-25 89.0 0.0 5e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) T7SS_ESX1_EccB PF05108.13 OEU23421.1 - 0.023 13.4 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B SR-25 PF10500.9 OEU23424.1 - 1.4 8.5 17.8 1.9 8.1 7.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RPS31 PF17067.5 OEU23425.1 - 0.11 12.7 0.2 0.23 11.6 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S31e Sec10 PF07393.11 OEU23426.1 - 0.61 8.4 6.1 0.62 8.4 6.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Orthopox_A36R PF05950.11 OEU23426.1 - 0.64 10.2 5.4 0.82 9.8 5.4 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Serglycin PF04360.12 OEU23428.1 - 0.014 15.3 0.3 0.024 14.6 0.3 1.4 1 0 0 1 1 1 0 Serglycin Pkinase PF00069.25 OEU23429.1 - 1.5e-25 90.1 0.1 2.5e-25 89.4 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU23429.1 - 4e-16 59.1 0.0 5.7e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU23429.1 - 0.00051 20.0 0.2 0.00067 19.6 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OEU23429.1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OEU23429.1 - 0.0061 15.5 0.0 0.0069 15.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain PIP49_C PF12260.8 OEU23429.1 - 0.0081 15.8 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 OEU23429.1 - 0.0093 14.8 0.0 0.014 14.2 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OEU23429.1 - 0.012 14.7 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OEU23429.1 - 0.014 14.8 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OEU23429.1 - 0.023 13.6 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC SR-25 PF10500.9 OEU23432.1 - 0.0015 18.2 3.0 0.0015 18.2 3.0 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4242 PF14026.6 OEU23432.1 - 0.022 14.9 0.2 0.052 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) ACOX PF01756.19 OEU23432.1 - 0.098 12.2 4.8 3 7.4 0.4 2.2 2 0 0 2 2 2 0 Acyl-CoA oxidase Sec16 PF12932.7 OEU23432.1 - 0.12 12.9 0.4 0.12 12.9 0.4 2.6 2 2 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Ribosomal_L16 PF00252.18 OEU23434.1 - 3.9e-36 124.0 0.1 5e-36 123.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3439 PF11921.8 OEU23436.1 - 0.0013 18.7 3.2 0.0027 17.7 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 OEU23436.1 - 0.11 12.4 6.7 0.37 10.8 6.7 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 OEU23436.1 - 0.18 10.3 4.4 0.23 10.0 4.4 1.2 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 OEU23436.1 - 0.21 10.9 11.3 0.29 10.4 11.3 1.2 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 OEU23436.1 - 3.1 6.8 18.3 4.6 6.3 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BBP2 PF07642.11 OEU23439.1 - 0.0055 15.9 0.2 0.12 11.6 0.0 2.1 2 0 0 2 2 2 2 Putative beta-barrel porin-2, OmpL-like. bbp2 Ribosomal_L28 PF00830.19 OEU23439.1 - 0.0098 16.1 0.4 0.15 12.3 0.0 2.6 3 0 0 3 3 3 1 Ribosomal L28 family DUF872 PF05915.12 OEU23441.1 - 0.11 12.6 7.1 0.15 12.2 7.0 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Tetraspanin PF00335.20 OEU23441.1 - 0.72 9.5 6.7 0.86 9.3 6.7 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF412 PF04217.13 OEU23441.1 - 1.2 9.0 6.0 1.4 8.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DUF1676 PF07898.13 OEU23441.1 - 9.8 6.2 11.3 12 5.8 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) PT PF04886.12 OEU23442.1 - 1.5e-05 24.4 131.5 0.023 14.2 21.4 7.0 4 1 3 7 7 7 5 PT repeat AP3D1 PF06375.11 OEU23442.1 - 0.013 15.8 2.8 0.029 14.6 2.8 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 MRF_C2 PF13888.6 OEU23442.1 - 0.042 13.7 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 NAD_binding_2 PF03446.15 OEU23442.1 - 0.067 13.4 4.6 3.3 7.9 0.7 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HA PF03457.14 OEU23443.1 - 1.1e-36 124.9 7.8 1.6e-19 70.0 0.8 2.1 2 0 0 2 2 2 2 Helicase associated domain Bystin PF05291.11 OEU23443.1 - 0.023 14.0 2.7 1.5 8.1 0.3 2.2 1 1 1 2 2 2 0 Bystin eIF3m_C_helix PF18005.1 OEU23443.1 - 0.038 13.7 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix DUF4936 PF16290.5 OEU23443.1 - 0.045 14.4 0.7 0.72 10.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) PTPRCAP PF15713.5 OEU23443.1 - 0.42 10.9 11.5 0.039 14.3 4.3 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RNA_pol_Rpc4 PF05132.14 OEU23443.1 - 0.78 10.2 2.8 0.37 11.2 0.4 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM176 PF14851.6 OEU23443.1 - 1.2 8.8 15.8 2.9 7.5 7.5 2.4 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.12 OEU23443.1 - 1.7 6.8 17.8 0.079 11.2 10.0 2.0 2 0 0 2 2 2 0 Nop14-like family BNIP2 PF12496.8 OEU23443.1 - 1.9 9.0 21.8 3.3 8.2 2.9 2.2 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Pox_Ag35 PF03286.14 OEU23443.1 - 2.7 7.8 17.4 0.25 11.1 8.4 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 OEU23443.1 - 2.9 7.4 18.6 0.039 13.6 8.1 2.1 2 0 0 2 2 2 0 PPP4R2 DUF2722 PF10846.8 OEU23443.1 - 6 5.7 22.7 0.076 12.0 13.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ras PF00071.22 OEU23444.1 - 1.7e-44 151.3 0.0 2.1e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU23444.1 - 2.1e-27 95.7 0.0 3.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU23444.1 - 1.6e-14 53.7 0.0 2.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OEU23444.1 - 1.4e-05 25.1 0.0 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OEU23444.1 - 1.8e-05 24.8 0.4 3.6e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OEU23444.1 - 1.8e-05 24.2 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OEU23444.1 - 3.4e-05 23.3 0.4 9.6e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OEU23444.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OEU23444.1 - 0.0037 17.0 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OEU23444.1 - 0.038 14.4 0.0 0.07 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OEU23444.1 - 0.047 13.9 0.0 0.77 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OEU23444.1 - 0.055 13.8 0.1 0.33 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF572 PF04502.13 OEU23444.1 - 0.097 12.3 4.3 0.13 11.9 4.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2375 PF09558.10 OEU23444.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) NACHT PF05729.12 OEU23444.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 NACHT domain Presenilin PF01080.17 OEU23444.1 - 0.39 9.4 2.1 0.5 9.1 2.1 1.1 1 0 0 1 1 1 0 Presenilin DLIC PF05783.11 OEU23444.1 - 1.3 7.8 6.4 0.47 9.2 0.1 2.7 1 1 2 3 3 3 0 Dynein light intermediate chain (DLIC) Menin PF05053.13 OEU23444.1 - 1.4 7.2 9.0 1.6 7.0 9.0 1.1 1 0 0 1 1 1 0 Menin GRP PF07172.11 OEU23444.1 - 3.6 8.3 12.7 1.1 10.0 9.9 1.5 2 0 0 2 2 1 0 Glycine rich protein family Macoilin PF09726.9 OEU23444.1 - 7.3 5.0 13.5 9.3 4.7 13.5 1.1 1 0 0 1 1 1 0 Macoilin family Ank_4 PF13637.6 OEU23445.1 - 4.6e-05 23.9 0.0 0.00088 19.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU23445.1 - 0.00047 20.7 0.0 2.4 8.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DNase_NucA_NucB PF14040.6 OEU23445.1 - 0.078 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Fasciclin PF02469.22 OEU23447.1 - 3.6e-14 53.1 2.2 1.1e-13 51.6 0.6 2.5 2 1 0 2 2 2 1 Fasciclin domain MRI PF15325.6 OEU23447.1 - 0.017 16.2 1.6 0.017 16.2 1.6 3.0 2 1 1 3 3 3 0 Modulator of retrovirus infection Presenilin PF01080.17 OEU23447.1 - 0.5 9.1 1.6 0.79 8.4 1.6 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OEU23447.1 - 6.7 4.9 7.7 10 4.3 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PDDEXK_3 PF13366.6 OEU23450.1 - 9.9e-12 45.3 1.0 1.8e-11 44.4 0.2 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 OEU23450.1 - 0.066 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1951 PF09188.10 OEU23450.1 - 0.085 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Hydrolase PF00702.26 OEU23450.1 - 0.1 12.9 0.3 0.36 11.1 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MtrG PF04210.13 OEU23451.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2207 PF09972.9 OEU23451.1 - 2.7 6.7 11.5 3.6 6.2 2.5 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Glyco_hydro_cc PF11790.8 OEU23452.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PT PF04886.12 OEU23453.1 - 0.049 13.2 24.1 1.1 8.9 24.1 2.2 1 1 0 1 1 1 0 PT repeat Guanylate_cyc PF00211.20 OEU23454.1 - 1.7e-46 158.2 0.0 3.1e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDEase_I PF00233.19 OEU23454.1 - 5.3e-30 104.9 2.5 1.2e-29 103.7 2.5 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2417 PF10329.9 OEU23454.1 - 0.037 13.4 0.3 0.095 12.1 0.0 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Ank_3 PF13606.6 OEU23455.1 - 0.0062 16.9 0.1 58 4.7 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OEU23455.1 - 0.011 16.3 0.0 11 6.8 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) AvrM_N PF18247.1 OEU23455.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain Pkinase PF00069.25 OEU23456.1 - 9.2e-15 54.7 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OEU23456.1 - 8.5e-08 31.4 0.1 1.1e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OEU23456.1 - 0.00018 20.9 0.0 0.0002 20.7 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OEU23456.1 - 0.0032 17.4 0.2 0.0051 16.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OEU23456.1 - 0.057 12.7 0.5 0.096 12.0 0.1 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Kdo PF06293.14 OEU23456.1 - 0.095 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OEU23456.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-MYND PF01753.18 OEU23457.1 - 4.4e-06 26.7 9.2 9.5e-06 25.6 9.2 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OEU23457.1 - 0.22 11.6 3.3 0.63 10.2 3.3 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3449 PF11931.8 OEU23457.1 - 0.87 9.3 4.9 0.97 9.2 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) PD40 PF07676.12 OEU23458.1 - 8.7e-07 28.7 0.7 0.022 14.7 0.1 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Gemin6 PF06372.12 OEU23458.1 - 0.0037 16.8 0.2 0.0058 16.2 0.2 1.2 1 0 0 1 1 1 1 Gemin6 protein DUF4621 PF15414.6 OEU23458.1 - 0.047 12.6 0.4 0.067 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) F-box-like PF12937.7 OEU23458.1 - 0.076 12.9 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF1513 PF07433.11 OEU23458.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF4844 PF16133.5 OEU23459.1 - 0.52 10.9 5.1 0.75 10.4 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) XAP5 PF04921.14 OEU23460.1 - 0.02 14.7 2.4 0.024 14.5 2.4 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Nop14 PF04147.12 OEU23460.1 - 0.024 12.9 3.5 0.025 12.8 3.5 1.0 1 0 0 1 1 1 0 Nop14-like family MCM_bind PF09739.9 OEU23460.1 - 0.089 11.2 7.6 0.11 10.9 7.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sporozoite_P67 PF05642.11 OEU23460.1 - 0.15 10.1 8.2 0.17 9.9 8.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM177 PF14774.6 OEU23460.1 - 0.19 12.1 2.3 0.25 11.7 2.3 1.3 1 0 0 1 1 1 0 FAM177 family Paramyxo_ncap PF00973.19 OEU23460.1 - 1.6 7.6 5.1 1.9 7.3 5.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NOA36 PF06524.12 OEU23460.1 - 2.3 7.5 11.2 3.4 6.9 11.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3494 PF11999.8 OEU23461.1 - 1.5e-51 175.0 17.9 1.8e-51 174.7 17.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF3540 PF12059.8 OEU23462.1 - 0.025 14.4 0.1 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) MFS_1 PF07690.16 OEU23465.1 - 2.6e-21 75.9 26.6 3.5e-21 75.5 26.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 OEU23467.1 - 0.00036 20.4 6.3 0.00036 20.4 6.3 1.7 2 0 0 2 2 2 1 Glycine zipper DUF1269 PF06897.12 OEU23467.1 - 0.0037 17.5 1.0 0.013 15.8 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 OEU23467.1 - 0.004 17.0 1.9 0.004 17.0 1.9 2.7 3 0 0 3 3 3 2 Glycine zipper 2TM domain DUF456 PF04306.13 OEU23467.1 - 0.016 15.5 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 OEU23467.1 - 0.032 14.4 8.5 0.059 13.5 8.5 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DCP2 PF05026.13 OEU23467.1 - 0.17 12.2 0.6 0.36 11.2 0.1 1.8 2 0 0 2 2 2 0 Dcp2, box A domain Gly-zipper_YMGG PF13441.6 OEU23467.1 - 0.19 11.5 13.8 0.62 9.9 13.8 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF2476 PF10630.9 OEU23468.1 - 0.0031 17.7 0.5 0.0064 16.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2476) Mem_trans PF03547.18 OEU23470.1 - 8.5e-20 70.5 4.2 8.5e-13 47.4 0.2 2.4 2 1 0 2 2 2 2 Membrane transport protein Tox-HNH-HHH PF15637.6 OEU23471.1 - 0.0027 17.9 4.7 0.0068 16.5 0.5 3.1 2 1 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif PhoD PF09423.10 OEU23472.1 - 0.0022 17.1 6.1 0.075 12.0 6.0 2.8 1 1 0 1 1 1 1 PhoD-like phosphatase ECSCR PF15820.5 OEU23472.1 - 0.024 14.4 0.1 0.098 12.5 0.1 2.0 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4307 PF14155.6 OEU23472.1 - 0.034 14.0 0.1 0.085 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Connexin PF00029.19 OEU23472.1 - 0.067 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Connexin adh_short PF00106.25 OEU23473.1 - 1.5e-38 132.2 1.2 1.7e-38 132.0 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU23473.1 - 1.7e-30 106.3 0.2 2.1e-30 106.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OEU23473.1 - 3.9e-10 39.9 0.1 5.3e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OEU23473.1 - 0.0052 16.2 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OEU23473.1 - 0.0062 15.9 0.1 0.013 14.8 0.1 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OEU23473.1 - 0.0065 16.4 0.2 0.013 15.4 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OEU23473.1 - 0.01 16.1 0.2 0.023 14.9 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OEU23473.1 - 0.021 15.2 0.0 0.031 14.7 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1776 PF08643.10 OEU23473.1 - 0.044 13.1 1.1 0.1 11.9 1.1 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) PseudoU_synth_2 PF00849.22 OEU23474.1 - 1.6e-18 67.3 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase PfaD_N PF18328.1 OEU23474.1 - 0.04 13.9 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain S4 PF01479.25 OEU23474.1 - 0.15 11.8 0.8 0.45 10.3 0.1 2.2 2 1 0 2 2 2 0 S4 domain Fer4_22 PF17179.4 OEU23475.1 - 0.35 11.8 2.3 0.54 11.1 0.9 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain CPP1-like PF11833.8 OEU23475.1 - 0.4 10.3 1.9 0.76 9.4 1.9 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like adh_short PF00106.25 OEU23476.1 - 7.3e-10 38.6 0.4 5.3e-07 29.3 0.1 3.1 3 1 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 OEU23476.1 - 9.7e-05 22.0 0.0 0.58 9.7 0.0 3.2 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Pox_ATPase-GT PF10640.9 OEU23478.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase AhpC-TSA_2 PF13911.6 OEU23479.1 - 0.00019 21.5 0.1 0.00025 21.1 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Telomere_Sde2_2 PF13297.6 OEU23479.1 - 0.099 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Telomere stability C-terminal Motilin_ghrelin PF04644.12 OEU23479.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Motilin/ghrelin YrhK PF14145.6 OEU23480.1 - 3.9e-18 65.1 18.1 5.1e-07 29.5 1.5 3.3 3 0 0 3 3 3 3 YrhK-like protein DUF4181 PF13789.6 OEU23480.1 - 0.019 15.3 4.9 1.8 8.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Oxidored_q3 PF00499.20 OEU23480.1 - 0.037 13.7 1.9 2.7 7.7 1.9 2.7 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Trp_oprn_chp PF09534.10 OEU23480.1 - 0.05 13.4 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RIC3 PF15361.6 OEU23480.1 - 0.1 13.0 1.3 18 5.7 1.4 3.3 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Adeno_E3_14_5 PF04834.12 OEU23480.1 - 0.13 12.8 1.9 1.4 9.5 0.1 2.7 2 1 1 3 3 3 0 Early E3 14.5 kDa protein Saf_2TM PF18303.1 OEU23480.1 - 0.27 10.8 1.3 18 4.9 0.0 3.2 4 0 0 4 4 4 0 SAVED-fused 2TM effector domain DUF2157 PF09925.9 OEU23480.1 - 0.43 10.4 4.1 2.1 8.2 0.3 3.4 2 2 0 2 2 2 0 Predicted membrane protein (DUF2157) Ocular_alb PF02101.15 OEU23480.1 - 0.55 9.1 5.5 0.83 8.5 0.2 2.2 1 1 1 2 2 2 0 Ocular albinism type 1 protein DUF2721 PF11026.8 OEU23480.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF2721) 7TMR-DISM_7TM PF07695.11 OEU23480.1 - 1.8 8.4 15.5 4.6 7.1 0.3 3.1 2 1 1 3 3 3 0 7TM diverse intracellular signalling Spermine_synth PF01564.17 OEU23481.1 - 5.5e-16 58.5 0.0 7.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 OEU23481.1 - 0.029 14.6 0.1 0.05 13.9 0.1 1.4 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase L1R_F9L PF02442.17 OEU23482.1 - 0.031 14.1 3.7 0.37 10.6 1.3 2.7 1 1 1 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses DUF1657 PF07870.11 OEU23482.1 - 0.25 11.3 2.6 0.33 10.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Cytochrom_C PF00034.21 OEU23482.1 - 0.52 11.5 5.5 0.39 11.9 0.4 3.1 2 0 0 2 2 2 0 Cytochrome c YtxH PF12732.7 OEU23482.1 - 1.1 9.8 3.7 3.3 8.3 0.1 3.1 2 1 0 2 2 2 0 YtxH-like protein Peptidase_C1 PF00112.23 OEU23483.1 - 3.4e-44 151.5 1.3 3.8e-44 151.4 1.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OEU23483.1 - 0.0029 16.5 3.7 0.091 11.5 0.3 2.8 3 0 0 3 3 3 2 Peptidase C1-like family MFS_1 PF07690.16 OEU23485.1 - 1.4e-27 96.5 22.2 2e-18 66.4 5.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OEU23485.1 - 1.5e-24 86.7 21.2 2.6e-23 82.6 21.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4834 PF16118.5 OEU23485.1 - 0.0045 17.9 1.2 0.19 12.7 0.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Mcm10 PF09332.11 OEU23486.1 - 0.021 14.3 1.2 0.027 13.9 1.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor TGF_beta_GS PF08515.12 OEU23486.1 - 0.074 12.6 0.4 0.17 11.4 0.4 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Troponin PF00992.20 OEU23487.1 - 0.029 14.7 3.1 0.044 14.1 3.1 1.2 1 0 0 1 1 1 0 Troponin EssA PF10661.9 OEU23487.1 - 0.14 12.0 5.0 0.19 11.6 5.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA FSA_C PF10479.9 OEU23487.1 - 0.71 7.9 5.8 0.8 7.8 5.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus EF-hand_7 PF13499.6 OEU23488.1 - 2.3e-08 34.4 0.0 0.0015 19.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OEU23488.1 - 3.3e-06 26.2 0.7 0.016 14.7 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OEU23488.1 - 2.9e-05 23.7 0.3 0.8 9.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain Cdc6_C PF09079.11 OEU23488.1 - 0.051 13.6 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF1860 PF08949.10 OEU23489.1 - 0.001 18.9 0.6 0.0013 18.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1860) DUF5406 PF17400.2 OEU23489.1 - 0.056 13.9 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5406) SbcCD_C PF13558.6 OEU23489.1 - 0.11 12.7 1.3 0.44 10.8 0.1 2.1 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit CPBP PF02517.16 OEU23491.1 - 1e-09 38.6 0.1 2.2e-09 37.6 0.1 1.4 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease EF-hand_13 PF17958.1 OEU23493.1 - 0.1 12.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain MARVEL PF01284.23 OEU23496.1 - 0.00038 20.5 10.0 0.0077 16.3 4.4 2.5 2 0 0 2 2 2 2 Membrane-associating domain MTCP1 PF08991.10 OEU23496.1 - 0.16 12.2 8.5 0.31 11.3 0.3 4.3 4 0 0 4 4 4 0 Mature-T-Cell Proliferation I type NDUFB10 PF10249.9 OEU23497.1 - 0.00045 20.7 0.5 0.0005 20.6 0.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Trp_oprn_chp PF09534.10 OEU23498.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2615 PF11027.8 OEU23498.1 - 0.032 14.3 0.1 0.054 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Chordopox_G3 PF06129.12 OEU23498.1 - 0.13 13.0 1.1 7.1 7.4 1.1 2.1 1 1 0 1 1 1 0 Chordopoxvirus G3 protein RSN1_7TM PF02714.15 OEU23500.1 - 8.7e-17 61.3 7.0 2.2e-16 60.0 7.0 1.8 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OEU23500.1 - 0.0004 20.2 3.7 0.0004 20.2 3.7 3.7 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport UPF0149 PF03695.13 OEU23501.1 - 0.072 13.4 0.8 0.13 12.6 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) DZR PF12773.7 OEU23501.1 - 0.093 12.8 1.3 0.21 11.6 1.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OEU23501.1 - 0.13 12.1 0.7 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain PNPase_C PF12111.8 OEU23501.1 - 0.14 11.6 2.0 0.24 10.9 0.8 1.9 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Keratin_2_head PF16208.5 OEU23503.1 - 0.00053 20.2 25.6 0.0058 16.8 10.2 2.1 1 1 1 2 2 2 2 Keratin type II head KRTAP PF11759.8 OEU23503.1 - 0.026 15.1 25.0 0.27 11.8 25.0 2.0 1 1 0 1 1 1 0 Keratin-associated matrix PhoLip_ATPase_C PF16212.5 OEU23504.1 - 1.9e-39 136.0 5.2 1.9e-39 136.0 5.2 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OEU23504.1 - 6.4e-14 51.4 1.8 2.6e-13 49.5 1.8 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OEU23504.1 - 8.8e-10 39.2 0.4 0.00037 20.9 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OEU23504.1 - 1.5e-05 25.0 0.0 8.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OEU23504.1 - 0.0037 17.0 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OEU23504.1 - 0.59 9.6 0.0 0.59 9.6 0.0 2.8 3 1 0 3 3 3 0 E1-E2 ATPase Methyltransf_24 PF13578.6 OEU23505.1 - 0.022 15.8 0.0 0.07 14.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Exostosin PF03016.15 OEU23506.1 - 0.00045 19.5 0.0 0.00063 19.0 0.0 1.2 1 0 0 1 1 1 1 Exostosin family YqgF PF14639.6 OEU23507.1 - 0.0067 16.2 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 Exostosin PF03016.15 OEU23508.1 - 6.3e-12 45.3 2.4 3.1e-11 43.1 2.4 1.9 1 1 0 1 1 1 1 Exostosin family DUF4460 PF14687.6 OEU23508.1 - 0.071 13.2 0.0 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) PC-Esterase PF13839.6 OEU23509.1 - 5.6e-11 42.7 1.4 5e-05 23.2 0.2 4.1 2 1 1 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SpoIIP PF07454.11 OEU23509.1 - 0.07 12.6 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nuc_sug_transp PF04142.15 OEU23511.1 - 2.1e-21 76.4 14.3 2.6e-21 76.1 14.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OEU23511.1 - 0.00011 22.4 28.7 0.0026 17.9 14.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family Glyco_tran_WbsX PF14307.6 OEU23512.1 - 4.8e-50 171.0 14.9 1.5e-30 106.9 6.6 4.7 3 1 0 3 3 3 3 Glycosyltransferase WbsX Acetyltransf_8 PF13523.6 OEU23512.1 - 0.067 12.9 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Orf78 PF06024.12 OEU23512.1 - 3.8 7.9 0.0 3.8 7.9 0.0 3.4 4 0 0 4 4 4 0 Orf78 (ac78) PT PF04886.12 OEU23513.1 - 0.032 13.8 1.2 0.057 13.0 1.2 1.4 1 0 0 1 1 1 0 PT repeat Nucleotid_trans PF03407.16 OEU23515.1 - 1.5e-05 25.1 0.5 0.00012 22.1 0.1 2.3 2 1 0 2 2 2 1 Nucleotide-diphospho-sugar transferase HSBP1 PF06825.12 OEU23516.1 - 3.4e-12 46.0 1.3 5e-12 45.5 1.3 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2089 PF09862.9 OEU23516.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) GET2 PF08690.10 OEU23516.1 - 1.1 8.9 8.2 1.3 8.6 8.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 SR-25 PF10500.9 OEU23516.1 - 6.4 6.3 8.2 8.4 5.9 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDE_Tnp_1_7 PF13843.6 OEU23517.1 - 6.2e-12 45.5 0.0 1.8e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Transposase IS4 OxoDH_E1alpha_N PF12573.8 OEU23518.1 - 0.19 11.5 0.4 0.45 10.3 0.4 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Phage_GPL PF05926.11 OEU23518.1 - 0.21 11.6 7.2 0.53 10.3 2.3 2.8 3 0 0 3 3 3 0 Phage head completion protein (GPL) Inhibitor_I69 PF13734.6 OEU23519.1 - 0.2 12.1 0.2 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 Spi protease inhibitor Gly-zipper_Omp PF13488.6 OEU23520.1 - 0.013 15.5 13.7 0.42 10.6 1.5 4.2 3 1 0 3 3 3 0 Glycine zipper PsaM PF07465.13 OEU23520.1 - 0.031 14.0 0.3 90 2.9 0.0 4.8 3 0 0 3 3 3 0 Photosystem I protein M (PsaM) Rick_17kDa_Anti PF05433.15 OEU23520.1 - 0.064 13.1 18.6 14 5.6 0.1 5.3 4 0 0 4 4 4 0 Glycine zipper 2TM domain Yae1_N PF09811.9 OEU23520.1 - 0.64 9.8 18.5 42 4.0 0.2 7.3 7 0 0 7 7 7 0 Essential protein Yae1, N terminal Gly-zipper_OmpA PF13436.6 OEU23520.1 - 1.3 8.8 14.4 22 4.9 0.3 4.9 4 0 0 4 4 4 0 Glycine-zipper domain Romo1 PF10247.9 OEU23520.1 - 8.5 6.8 17.3 11 6.4 0.9 4.5 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 PT PF04886.12 OEU23521.1 - 8.1e-15 54.1 125.8 0.0014 18.1 5.5 12.3 2 1 7 10 10 10 6 PT repeat HEAT_EZ PF13513.6 OEU23521.1 - 0.048 14.2 0.1 98 3.6 0.0 4.8 4 1 0 4 4 4 0 HEAT-like repeat Galactosyl_T PF01762.21 OEU23522.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase DHQS PF01959.16 OEU23522.1 - 0.23 10.3 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase II HA PF03457.14 OEU23523.1 - 4e-54 180.8 5.9 4.9e-18 65.2 0.2 3.4 4 0 0 4 4 4 3 Helicase associated domain PMR5N PF14416.6 OEU23523.1 - 0.035 14.4 1.8 20 5.6 0.1 4.0 3 1 1 4 4 4 0 PMR5 N terminal Domain DUF1257 PF06868.11 OEU23523.1 - 0.11 12.8 0.5 0.85 9.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1257) Ribosomal_L31 PF01197.18 OEU23524.1 - 0.067 13.4 0.2 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L31 Sulfotransfer_3 PF13469.6 OEU23527.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Exostosin PF03016.15 OEU23529.1 - 1.7e-18 66.9 0.0 1.8e-15 57.0 0.0 3.0 2 0 0 2 2 2 2 Exostosin family DAGK_cat PF00781.24 OEU23530.1 - 0.076 12.6 0.5 4.5 6.9 0.0 2.8 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain 2OG-FeII_Oxy PF03171.20 OEU23531.1 - 8.5e-15 55.1 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OEU23531.1 - 0.0077 17.0 0.2 0.013 16.2 0.2 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_tranf_2_5 PF13712.6 OEU23533.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family SR-25 PF10500.9 OEU23533.1 - 7.7 6.0 10.4 0.16 11.5 2.5 2.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Cornifin PF02389.15 OEU23534.1 - 0.00047 20.4 20.3 0.00069 19.8 20.3 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family Mucin PF01456.17 OEU23534.1 - 0.2 11.6 30.4 0.77 9.7 30.4 2.0 1 1 0 1 1 1 0 Mucin-like glycoprotein PARM PF17061.5 OEU23534.1 - 0.41 10.7 13.2 0.53 10.4 13.2 1.2 1 0 0 1 1 1 0 PARM PT PF04886.12 OEU23534.1 - 0.43 10.2 14.3 3e+03 -2.1 14.3 3.5 1 1 0 1 1 1 0 PT repeat Dicty_REP PF05086.12 OEU23534.1 - 1.2 7.0 12.3 1.4 6.8 12.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Endostatin PF06482.11 OEU23534.1 - 5.8 6.3 7.9 6.9 6.0 7.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Sdh5 PF03937.16 OEU23536.1 - 0.025 14.5 0.4 0.043 13.8 0.4 1.3 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Pox_TAA1 PF03295.14 OEU23536.1 - 0.047 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal Lipase_3 PF01764.25 OEU23539.1 - 2.5e-08 33.9 0.1 1.2e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 OEU23539.1 - 0.00077 19.6 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 OEU23539.1 - 0.0023 17.2 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SCRL PF06876.12 OEU23539.1 - 0.0073 16.5 0.5 0.012 15.8 0.5 1.3 1 0 0 1 1 1 1 Plant self-incompatibility response (SCRL) protein Chlorophyllase2 PF12740.7 OEU23539.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 OEU23539.1 - 0.045 13.3 0.0 0.076 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) T4-Gluco-transf PF09198.10 OEU23539.1 - 0.12 12.0 0.5 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase Abhydrolase_1 PF00561.20 OEU23539.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipid_DES PF08557.10 OEU23540.1 - 0.01 15.3 7.9 1e+02 2.5 0.0 5.8 6 0 0 6 6 6 0 Sphingolipid Delta4-desaturase (DES) OGFr_III PF04680.13 OEU23540.1 - 0.93 10.2 23.9 1.2e+02 3.5 0.1 8.2 8 1 0 8 8 8 0 Opioid growth factor receptor repeat LEA_6 PF10714.9 OEU23540.1 - 3.1 7.9 10.2 18 5.5 1.0 3.2 1 1 2 3 3 3 0 Late embryogenesis abundant protein 18 EF-hand_1 PF00036.32 OEU23541.1 - 2.6e-08 32.8 0.1 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OEU23541.1 - 8.2e-08 31.6 0.2 0.00035 20.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OEU23541.1 - 2.3e-07 30.0 0.6 0.00066 19.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OEU23541.1 - 1.2e-06 28.9 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OEU23541.1 - 7.8e-06 25.6 0.1 0.00019 21.2 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair SYCP2_ARLD PF18581.1 OEU23541.1 - 0.0083 16.1 0.0 0.0098 15.9 0.0 1.1 1 0 0 1 1 1 1 Synaptonemal complex 2 armadillo-repeat-like domain EF-hand_4 PF12763.7 OEU23541.1 - 0.097 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand BUD22 PF09073.10 OEU23542.1 - 1.5e-07 31.2 53.8 1.5e-07 31.2 53.8 3.9 3 1 0 3 3 3 2 BUD22 Pilin_N PF07790.11 OEU23543.1 - 0.27 12.2 1.8 4.4 8.3 0.1 2.8 2 1 1 3 3 3 0 Archaeal Type IV pilin, N-terminal PT PF04886.12 OEU23544.1 - 3.7e-14 52.0 349.8 0.0028 17.2 11.4 19.4 6 5 4 10 10 10 6 PT repeat DUF3192 PF11399.8 OEU23546.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) Cu2_monoox_C PF03712.15 OEU23547.1 - 1.7e-08 34.2 0.5 4.4e-08 32.8 0.4 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Med13_N PF11597.8 OEU23547.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Meth_synt_1 PF08267.12 OEU23549.1 - 0.041 13.4 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain TMEM51 PF15345.6 OEU23549.1 - 0.23 11.3 11.7 0.15 11.9 9.8 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 WBP-1 PF11669.8 OEU23549.1 - 2.5 8.8 7.7 0.92 10.2 3.7 2.2 2 1 0 2 2 2 0 WW domain-binding protein 1 Sulfatase PF00884.23 OEU23550.1 - 5.5e-30 104.8 2.0 1.1e-29 103.9 2.0 1.4 1 0 0 1 1 1 1 Sulfatase Glycophorin_A PF01102.18 OEU23550.1 - 0.012 15.8 0.2 0.012 15.8 0.2 2.9 3 1 0 3 3 3 0 Glycophorin A DUF5305 PF17231.2 OEU23550.1 - 0.032 13.6 6.3 0.056 12.8 4.3 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Sigma_reg_N PF13800.6 OEU23550.1 - 1.3 9.4 6.4 1.2 9.4 1.3 3.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PT PF04886.12 OEU23551.1 - 1.3e-11 43.8 44.1 0.81 9.3 44.1 2.6 1 1 0 1 1 1 1 PT repeat Glycoprotein_G PF00802.19 OEU23551.1 - 3.2 7.0 15.4 3.7 6.8 15.4 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Cwf_Cwc_15 PF04889.12 OEU23552.1 - 0.098 12.4 9.1 0.21 11.3 9.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OEU23552.1 - 0.21 10.9 6.8 0.32 10.3 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein PT PF04886.12 OEU23553.1 - 0.00067 19.2 26.7 0.00067 19.2 26.7 3.9 3 1 1 4 4 4 3 PT repeat Mitofilin PF09731.9 OEU23554.1 - 0.0037 16.2 17.2 0.0042 16.0 17.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF885 PF05960.11 OEU23554.1 - 0.015 14.9 11.6 0.018 14.7 11.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) MT0933_antitox PF14013.6 OEU23554.1 - 0.18 12.1 0.5 0.18 12.1 0.5 3.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein SH3BP5 PF05276.14 OEU23554.1 - 0.23 11.2 15.8 0.4 10.5 15.8 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) NACHT_N PF17100.5 OEU23554.1 - 0.76 9.6 19.7 1.2 9.0 8.9 2.4 1 1 2 3 3 3 0 N-terminal domain of NWD NACHT-NTPase SAPS PF04499.15 OEU23554.1 - 2 7.1 7.9 2.5 6.8 7.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 OEU23554.1 - 2.4 7.5 21.3 3.2 7.0 21.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 OEU23554.1 - 2.6 5.1 11.4 2.9 4.9 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF883 PF05957.13 OEU23554.1 - 8.1 7.1 21.6 1.8e+04 -3.7 21.7 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.25 OEU23556.1 - 3.1e-24 85.8 0.0 3.5e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OEU23556.1 - 1.1e-12 47.8 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2448 PF10476.9 OEU23557.1 - 6.7 6.5 5.8 4.7 7.0 2.5 2.4 2 1 1 3 3 3 0 Protein of unknown function C-terminus (DUF2448) DUF1115 PF06544.12 OEU23559.1 - 0.33 11.0 2.9 0.77 9.8 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1115) Ank_2 PF12796.7 OEU23560.1 - 1e-06 29.3 0.1 0.01 16.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU23560.1 - 6.6e-05 23.4 2.2 0.19 12.3 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OEU23560.1 - 0.0041 17.5 2.0 0.17 12.4 0.1 3.6 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OEU23560.1 - 0.018 15.3 0.4 1.6 9.1 0.1 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) TPR_4 PF07721.14 OEU23560.1 - 0.11 13.2 1.5 6 7.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OEU23560.1 - 1 9.6 4.8 11 6.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CS PF04969.16 OEU23561.1 - 1.3e-12 48.5 1.4 5.3e-12 46.6 1.4 2.0 1 1 0 1 1 1 1 CS domain zf-CCCH_4 PF18044.1 OEU23562.1 - 0.0015 18.3 17.1 0.014 15.2 4.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Presenilin PF01080.17 OEU23562.1 - 0.07 11.9 17.8 0.021 13.6 4.7 2.4 2 0 0 2 2 2 0 Presenilin zf-CCCH PF00642.24 OEU23562.1 - 4.3 7.4 15.9 0.34 10.9 2.2 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OEU23562.1 - 4.8 7.4 14.5 9.2 6.5 3.0 3.3 2 2 0 2 2 2 0 Zinc finger domain DUF4175 PF13779.6 OEU23562.1 - 8.2 4.2 13.1 13 3.5 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CBM_14 PF01607.24 OEU23564.1 - 2.2e-06 27.7 2.7 2.2e-06 27.7 2.7 2.9 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain DUF1836 PF08876.11 OEU23565.1 - 0.093 12.8 0.1 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) PH PF00169.29 OEU23566.1 - 2.7 8.6 5.3 1.5 9.4 0.1 3.4 4 0 0 4 4 4 0 PH domain Orn_Arg_deC_N PF02784.16 OEU23567.1 - 7.6e-27 94.3 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OEU23567.1 - 2e-06 28.0 0.0 6.2e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OEU23567.1 - 0.00028 20.4 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldo_ket_red PF00248.21 OEU23569.1 - 1.5e-41 142.5 0.0 2e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Soyouz_module PF14313.6 OEU23570.1 - 0.011 15.5 0.1 5.1 6.9 0.0 3.3 4 0 0 4 4 4 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Androgen_recep PF02166.16 OEU23571.1 - 0.32 9.8 1.4 0.39 9.5 1.4 1.1 1 0 0 1 1 1 0 Androgen receptor PBP1_TM PF14812.6 OEU23571.1 - 0.84 10.0 5.6 1.8 9.0 5.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt20 PF12090.8 OEU23571.1 - 0.93 9.1 9.0 0.42 10.2 6.1 1.7 2 0 0 2 2 2 0 Spt20 family CDC27 PF09507.10 OEU23572.1 - 1.2e-17 64.5 45.3 1.6e-17 64.0 45.3 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Dehydrin PF00257.19 OEU23572.1 - 0.023 15.3 5.6 0.023 15.3 5.6 3.6 2 2 1 3 3 3 0 Dehydrin PPI_Ypi1 PF07491.11 OEU23572.1 - 1 9.2 9.5 0.064 13.1 1.3 3.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor NDUFA12 PF05071.16 OEU23572.1 - 3.2 8.7 9.5 1.9 9.3 2.0 2.9 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 KptA_kDCL PF18176.1 OEU23573.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Lzipper-MIP1 PF14389.6 OEU23573.1 - 0.021 15.1 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 ATF7IP_BD PF16788.5 OEU23573.1 - 0.033 14.3 0.7 0.033 14.3 0.7 3.1 3 0 0 3 3 3 0 ATF-interacting protein binding domain Siah-Interact_N PF09032.11 OEU23573.1 - 0.061 13.6 0.7 0.061 13.6 0.7 2.7 3 0 0 3 3 3 0 Siah interacting protein, N terminal ZapB PF06005.12 OEU23573.1 - 8 7.0 11.9 0.35 11.3 2.5 2.6 2 1 0 2 2 2 0 Cell division protein ZapB LRR_4 PF12799.7 OEU23575.1 - 0.017 15.5 6.4 2.1 8.9 0.2 4.3 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 OEU23575.1 - 0.19 12.0 0.9 0.53 10.5 0.1 2.2 2 0 0 2 2 2 0 FNIP Repeat Aldo_ket_red PF00248.21 OEU23576.1 - 6.1e-21 74.9 0.0 1.9e-20 73.3 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Alpha_Helical PF18489.1 OEU23576.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha helical domain zf-MYND PF01753.18 OEU23577.1 - 8.7e-07 28.9 12.0 1.5e-06 28.2 12.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OEU23577.1 - 0.011 16.0 12.9 0.027 14.8 12.9 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ODV-E18 PF10717.9 OEU23578.1 - 0.017 14.9 0.6 1.2 9.0 0.4 3.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 TMEM164 PF14808.6 OEU23578.1 - 0.13 11.6 7.0 0.23 10.8 1.2 2.9 3 0 0 3 3 3 0 TMEM164 family Myb_DNA-binding PF00249.31 OEU23579.1 - 1.4e-26 92.4 10.9 1.4e-10 41.2 0.1 3.4 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OEU23579.1 - 6.5e-25 87.2 10.4 2.7e-09 37.2 0.1 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OEU23579.1 - 2.8e-05 23.9 0.9 0.0012 18.7 0.0 2.6 2 1 0 2 2 2 1 Myb DNA-binding like Tox-GHH PF15636.6 OEU23579.1 - 0.047 13.7 1.0 2.6 8.1 0.0 2.7 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Rap1_C PF11626.8 OEU23579.1 - 0.06 13.4 0.6 10 6.3 0.7 2.9 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Atg29_N PF18388.1 OEU23579.1 - 0.085 12.7 3.5 0.79 9.6 0.2 2.7 3 0 0 3 3 3 0 Atg29 N-terminal domain Myb_DNA-bind_5 PF13873.6 OEU23579.1 - 1.7 8.7 8.0 23 5.1 0.2 4.4 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OEU23579.1 - 4.2 7.6 9.7 0.38 11.0 0.7 3.0 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 Ferric_reduct PF01794.19 OEU23580.1 - 1.7e-11 44.3 7.2 1.7e-11 44.3 7.2 3.3 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OEU23580.1 - 3.3e-07 30.6 2.1 0.0022 18.1 0.0 4.0 4 0 0 4 4 4 2 Ferric reductase NAD binding domain YqzM PF14141.6 OEU23580.1 - 0.047 13.7 1.4 0.16 12.1 1.4 1.9 1 0 0 1 1 1 0 YqzM-like protein EH_Signature PF15611.6 OEU23580.1 - 0.18 11.2 0.2 1.2 8.5 0.2 2.0 2 0 0 2 2 2 0 EH_Signature domain Orf78 PF06024.12 OEU23580.1 - 0.32 11.3 0.1 0.32 11.3 0.1 5.7 7 1 0 7 7 7 0 Orf78 (ac78) Serinc PF03348.15 OEU23580.1 - 0.35 9.7 8.5 1.1 8.2 1.3 3.9 2 1 0 2 2 2 0 Serine incorporator (Serinc) Tmem26 PF09772.9 OEU23580.1 - 0.96 8.7 6.1 0.69 9.2 2.2 2.7 3 0 0 3 3 3 0 Transmembrane protein 26 Pox_Ag35 PF03286.14 OEU23580.1 - 1.6 8.5 13.4 1.7 8.4 0.0 4.4 4 1 0 4 4 4 0 Pox virus Ag35 surface protein Glyco_hydro_38N PF01074.22 OEU23582.1 - 6.6e-62 209.5 4.3 1e-61 208.9 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OEU23582.1 - 1.2e-31 110.5 0.2 2.3e-31 109.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OEU23582.1 - 1.9e-15 56.8 0.0 6e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OEU23582.1 - 2.1e-06 27.8 0.0 6.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain zf-RanBP PF00641.18 OEU23583.1 - 0.15 11.4 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF3439 PF11921.8 OEU23586.1 - 0.014 15.3 14.9 0.028 14.4 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 OEU23586.1 - 6.2 6.8 31.0 7.3 6.6 18.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF273 PF03314.14 OEU23587.1 - 8.6e-16 58.2 0.2 2.1e-14 53.6 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF273 DUF2684 PF10885.8 OEU23587.1 - 0.031 14.4 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) Sacchrp_dh_NADP PF03435.18 OEU23588.1 - 1.4e-08 35.0 0.2 3.8e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OEU23588.1 - 0.0017 18.3 0.1 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 KR domain DUF3246 PF11596.8 OEU23588.1 - 0.14 11.6 10.9 3.6 7.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SET PF00856.28 OEU23589.1 - 1e-08 35.8 0.3 1e-08 35.8 0.3 3.0 2 2 0 2 2 2 1 SET domain ZinT PF09223.11 OEU23589.1 - 0.016 15.1 1.3 0.031 14.2 1.3 1.5 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment tRNA_bind PF01588.20 OEU23590.1 - 2.4e-09 37.2 0.0 3.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Viral_helicase1 PF01443.18 OEU23591.1 - 0.75 9.5 7.4 3.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TPR_2 PF07719.17 OEU23592.1 - 1.8e-08 33.9 0.4 0.028 14.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OEU23592.1 - 4.4e-07 29.5 0.1 0.0018 18.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OEU23592.1 - 3.7e-06 27.1 0.1 0.00088 19.5 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OEU23592.1 - 6.7e-06 25.7 0.5 0.0034 17.0 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 OEU23592.1 - 1.1e-05 25.3 4.2 0.19 12.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OEU23592.1 - 6.1e-05 23.4 0.0 0.43 11.1 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OEU23592.1 - 0.0026 18.4 0.0 3.9 8.5 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OEU23592.1 - 0.011 16.4 0.0 7.3 7.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OEU23592.1 - 0.018 14.9 1.8 0.1 12.5 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OEU23592.1 - 0.021 14.8 0.0 0.4 10.8 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OEU23592.1 - 0.031 14.6 2.7 0.61 10.6 0.0 3.6 4 1 1 5 5 3 0 Tetratricopeptide repeat SR-25 PF10500.9 OEU23592.1 - 0.065 12.8 9.9 0.098 12.3 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_MalT PF17874.1 OEU23592.1 - 0.067 12.6 0.0 1.3 8.4 0.0 2.3 2 1 0 2 2 2 0 MalT-like TPR region DUF5125 PF17163.4 OEU23593.1 - 0.056 13.6 0.1 0.062 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) Sulfatase PF00884.23 OEU23594.1 - 1.1e-37 130.2 5.6 1.6e-37 129.5 5.6 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OEU23594.1 - 0.00012 21.8 5.7 0.084 12.4 5.7 2.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DNA_pol_phi PF04931.13 OEU23596.1 - 0.49 8.4 14.8 0.54 8.3 14.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 OEU23596.1 - 2.2 8.1 13.8 0.36 10.7 5.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 OEU23596.1 - 3.7 8.0 21.9 2.3 8.7 8.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 OEU23596.1 - 8.9 6.6 16.6 12 6.3 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF285 PF03382.14 OEU23597.1 - 2.9e-194 633.9 109.5 9.7e-39 131.9 13.4 3.9 1 1 5 6 6 6 6 Mycoplasma protein of unknown function, DUF285 BssS PF13991.6 OEU23597.1 - 3.2e-05 23.9 2.5 31 4.7 0.0 6.9 9 0 0 9 9 9 2 BssS protein family FNIP PF05725.12 OEU23597.1 - 9.1 6.5 17.3 8 6.7 0.2 6.7 8 1 0 8 8 8 0 FNIP Repeat Gly-zipper_Omp PF13488.6 OEU23598.1 - 0.0026 17.7 47.2 0.35 10.9 9.6 6.8 1 1 5 6 6 6 3 Glycine zipper MccV PF17508.2 OEU23598.1 - 0.32 11.6 11.0 19 5.9 0.5 4.9 1 1 5 6 6 6 0 Microcin V bacteriocin Yae1_N PF09811.9 OEU23598.1 - 1.1 9.1 36.6 9.6 6.0 1.4 10.2 4 3 6 10 10 10 0 Essential protein Yae1, N terminal Rick_17kDa_Anti PF05433.15 OEU23598.1 - 2.9 7.8 64.4 52 3.8 10.3 8.3 2 2 4 6 6 6 0 Glycine zipper 2TM domain DUF669 PF05037.13 OEU23599.1 - 0.011 15.9 0.4 0.011 15.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF669) Fer4_16 PF13484.6 OEU23601.1 - 0.14 13.1 0.3 0.14 13.1 0.3 3.2 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain NAD_binding_6 PF08030.12 OEU23601.1 - 7.1 6.7 9.0 2.8 8.0 2.3 2.4 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Sulfotransfer_3 PF13469.6 OEU23602.1 - 0.032 14.6 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Sulfotransferase family Fasciclin PF02469.22 OEU23605.1 - 4.9e-15 55.9 0.0 7.1e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain adh_short PF00106.25 OEU23606.1 - 1.5e-20 73.5 0.0 2.5e-11 43.4 0.0 2.2 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU23606.1 - 3.7e-17 62.7 0.0 2.3e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 OEU23606.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OEU23606.1 - 0.029 13.8 0.1 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family COPI_C PF06957.11 OEU23608.1 - 2.9 6.6 6.1 3.9 6.1 6.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Myb_DNA-binding PF00249.31 OEU23609.1 - 0.00012 22.2 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain NECFESHC PF16621.5 OEU23610.1 - 0.012 15.6 5.0 0.012 15.6 5.0 2.0 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 DUF2207 PF09972.9 OEU23610.1 - 0.08 11.7 0.5 0.13 11.0 0.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1298 PF06974.13 OEU23612.1 - 1.3e-18 67.4 0.0 6.9e-17 61.7 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1298) Condensation PF00668.20 OEU23612.1 - 0.0027 16.5 0.8 0.0048 15.6 0.0 1.7 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 OEU23612.1 - 0.0033 17.2 0.8 0.074 12.8 0.0 2.7 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain TauE PF01925.19 OEU23613.1 - 4.4e-23 82.1 1.1 6.2e-11 42.4 1.2 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE PTS_EIIC_2 PF13303.6 OEU23613.1 - 0.047 12.7 5.5 3.3 6.7 2.5 2.4 2 1 0 2 2 2 0 Phosphotransferase system, EIIC MGC-24 PF05283.11 OEU23613.1 - 1.9 8.9 10.4 0.14 12.6 3.8 2.3 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-MYND PF01753.18 OEU23614.1 - 1.9e-08 34.2 18.9 4.1e-08 33.2 18.9 1.6 1 0 0 1 1 1 1 MYND finger DUF4262 PF14081.6 OEU23614.1 - 0.032 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) zf-Mss51 PF13824.6 OEU23614.1 - 1.2 9.3 11.8 2.7 8.2 11.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 HSF_DNA-bind PF00447.17 OEU23616.1 - 9.1e-20 71.1 0.2 9.8e-20 71.0 0.2 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding HA PF03457.14 OEU23617.1 - 5e-42 142.1 2.0 5.8e-21 74.6 0.3 2.1 2 0 0 2 2 2 2 Helicase associated domain CpeS PF09367.10 OEU23617.1 - 0.0012 18.8 0.8 0.48 10.3 0.1 2.2 2 0 0 2 2 2 2 CpeS-like protein DUF1934 PF09148.10 OEU23617.1 - 0.0044 17.0 5.0 0.26 11.3 0.5 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF1934) DUF2199 PF09965.9 OEU23617.1 - 0.019 15.0 0.2 6.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) VHS PF00790.19 OEU23617.1 - 0.037 13.9 1.0 0.081 12.8 0.1 2.0 2 1 1 3 3 3 0 VHS domain Cas_Csy4 PF09618.10 OEU23617.1 - 0.066 13.4 2.3 2 8.5 0.2 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) PMR5N PF14416.6 OEU23617.1 - 0.071 13.4 0.7 17 5.8 0.0 2.7 3 0 0 3 3 3 0 PMR5 N terminal Domain Cas6b_C PF17262.2 OEU23617.1 - 0.1 12.7 1.0 8.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Cas6b C-terminal domain IstB_IS21_ATP PF08483.11 OEU23617.1 - 0.11 12.4 0.0 18 5.4 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding N-terminal HA PF03457.14 OEU23618.1 - 1.7e-19 69.9 0.1 1.9e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Helicase associated domain Glucosamine_iso PF01182.20 OEU23619.1 - 3.5e-27 95.8 0.0 4.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DNApol_Exo PF18136.1 OEU23620.1 - 9.7 5.2 11.7 0.14 11.3 0.7 2.4 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain SARAF PF06682.12 OEU23621.1 - 0.011 15.4 0.7 0.036 13.7 0.2 2.0 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1180 PF06679.12 OEU23621.1 - 0.025 15.0 1.0 0.025 15.0 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF5325 PF17259.2 OEU23621.1 - 0.12 12.3 3.8 0.56 10.1 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Zip PF02535.22 OEU23621.1 - 0.16 11.2 1.1 0.27 10.4 1.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.9 OEU23621.1 - 0.24 11.0 6.8 0.36 10.4 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orf78 PF06024.12 OEU23621.1 - 0.65 10.3 2.1 1.3 9.4 0.1 2.5 2 1 1 3 3 3 0 Orf78 (ac78) Lin-8 PF03353.15 OEU23621.1 - 0.81 9.2 3.4 1.6 8.3 3.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Trypan_PARP PF05887.11 OEU23621.1 - 0.93 9.5 0.0 0.93 9.5 0.0 2.9 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) Macoilin PF09726.9 OEU23621.1 - 5.4 5.5 10.9 30 3.0 11.1 1.6 1 1 1 2 2 2 0 Macoilin family CAP_N PF01213.19 OEU23622.1 - 1 8.8 21.8 0.031 13.8 3.9 3.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal FAM178 PF14816.6 OEU23622.1 - 5.1 6.0 13.0 1.9 7.4 6.0 2.6 2 0 0 2 2 2 0 Family of unknown function, FAM178 DUF603 PF04645.12 OEU23623.1 - 0.02 14.6 0.4 0.039 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Anthrax_toxA PF03497.16 OEU23623.1 - 0.053 13.6 1.3 0.065 13.4 0.1 1.8 2 0 0 2 2 2 0 Anthrax toxin LF subunit zf-C4H2 PF10146.9 OEU23623.1 - 1 9.6 7.0 7.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein ABC_tran PF00005.27 OEU23625.1 - 3.2e-30 105.4 0.1 4.5e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OEU23625.1 - 0.00017 21.6 0.6 0.16 11.8 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OEU23625.1 - 0.00029 20.8 0.1 0.00048 20.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 OEU23625.1 - 0.00058 19.4 0.1 0.84 9.0 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OEU23625.1 - 0.0013 18.4 0.5 0.0029 17.3 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OEU23625.1 - 0.0093 16.2 0.3 0.029 14.6 0.2 1.9 1 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OEU23625.1 - 0.02 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OEU23625.1 - 0.044 14.3 0.3 0.073 13.6 0.3 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OEU23625.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OEU23625.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OEU23625.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SUIM_assoc PF16619.5 OEU23626.1 - 0.034 14.2 5.0 0.093 12.8 5.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hamartin PF04388.12 OEU23626.1 - 8.7 4.9 6.8 13 4.3 1.8 2.0 2 0 0 2 2 2 0 Hamartin protein LAP1C PF05609.12 OEU23627.1 - 0.0013 18.0 18.4 0.0016 17.6 18.4 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Glycophorin_A PF01102.18 OEU23627.1 - 0.35 11.1 0.1 0.35 11.1 0.1 2.6 2 1 1 3 3 3 0 Glycophorin A BPL_N PF09825.9 OEU23627.1 - 0.49 9.4 9.9 0.66 9.0 9.9 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF4064 PF13273.6 OEU23627.1 - 1 9.7 0.0 1 9.7 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) RsgA_GTPase PF03193.16 OEU23628.1 - 0.1 12.5 0.4 49 3.8 0.0 3.6 4 0 0 4 4 4 0 RsgA GTPase YceD PF02620.17 OEU23629.1 - 8.2e-06 25.9 4.4 0.16 12.1 3.4 3.4 2 1 0 2 2 2 2 Large ribosomal RNA subunit accumulation protein YceD Surp PF01805.20 OEU23629.1 - 0.17 11.9 2.5 0.44 10.6 2.5 1.7 1 0 0 1 1 1 0 Surp module AGH PF17558.2 OEU23629.1 - 1.1 9.4 6.2 0.13 12.4 1.3 1.9 2 0 0 2 2 2 0 Androgenic gland hormone Utp14 PF04615.13 OEU23629.1 - 1.2 7.7 15.2 2.5 6.6 15.2 1.5 1 1 0 1 1 1 0 Utp14 protein Peroxin-13_N PF04088.13 OEU23629.1 - 5.3 7.3 7.8 0.37 11.0 1.3 2.1 2 1 0 2 2 2 0 Peroxin 13, N-terminal region CRA PF06589.11 OEU23629.1 - 9.1 6.4 14.7 3.4 7.8 6.4 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Serinc PF03348.15 OEU23629.1 - 10 4.9 5.5 1.8 7.4 0.3 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) Antirestrict PF03230.13 OEU23630.1 - 0.073 13.1 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Antirestriction protein Leuk-A4-hydro_C PF09127.11 OEU23630.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Herpes_TAF50 PF03326.13 OEU23632.1 - 0.88 8.2 6.2 1.5 7.4 6.2 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) HA PF03457.14 OEU23633.1 - 3.2e-05 24.2 0.1 9e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain HSF_DNA-bind PF00447.17 OEU23633.1 - 0.0001 22.8 0.1 0.0001 22.8 0.1 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding zf-CXXC PF02008.20 OEU23633.1 - 1.1 9.4 4.7 6.1 7.0 0.5 2.8 2 0 0 2 2 2 0 CXXC zinc finger domain Peptidase_M14 PF00246.24 OEU23635.1 - 1.5e-07 31.6 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 OEU23635.1 - 4.7e-06 25.9 0.0 6.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 OEU23635.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) DUF4692 PF15763.5 OEU23637.1 - 0.81 10.1 5.8 1.1 9.8 5.8 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FAM220 PF15487.6 OEU23639.1 - 0.16 11.6 4.5 0.2 11.3 4.5 1.0 1 0 0 1 1 1 0 FAM220 family MGC-24 PF05283.11 OEU23639.1 - 0.74 10.3 7.6 1 9.8 7.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PIN_4 PF13638.6 OEU23641.1 - 1.2e-09 38.5 0.3 2.5e-09 37.5 0.3 1.4 1 1 0 1 1 1 1 PIN domain PIN_12 PF16289.5 OEU23641.1 - 0.082 13.4 1.5 0.14 12.6 1.5 1.4 1 0 0 1 1 1 0 PIN domain MeaB PF03308.16 OEU23641.1 - 0.3 10.0 3.4 0.46 9.4 3.4 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DDE_3 PF13358.6 OEU23642.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Nucleoporin_N PF08801.11 OEU23642.1 - 0.056 12.2 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Sel1 PF08238.12 OEU23645.1 - 0.0016 19.1 0.5 2.5 8.9 0.1 2.6 2 0 0 2 2 2 2 Sel1 repeat Fis1_TPR_N PF14852.6 OEU23645.1 - 0.1 12.3 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TPR_17 PF13431.6 OEU23645.1 - 3.7 8.1 5.7 7.2 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat APAF1_C PF17908.1 OEU23646.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 APAF-1 helical domain CssAB PF16831.5 OEU23647.1 - 0.028 14.8 1.0 0.088 13.2 1.0 1.8 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 Bet_v_1 PF00407.19 OEU23647.1 - 0.041 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family PAP2 PF01569.21 OEU23648.1 - 3.8e-26 91.5 0.2 9.8e-26 90.1 0.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily SARAF PF06682.12 OEU23648.1 - 3.9e-05 23.5 0.0 5.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis 7tm_1 PF00001.21 OEU23648.1 - 7.3e-05 22.2 0.1 0.0024 17.2 0.1 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PAP2_3 PF14378.6 OEU23648.1 - 0.00013 21.7 1.3 0.23 11.1 0.6 2.5 3 0 0 3 3 3 2 PAP2 superfamily FAM176 PF14851.6 OEU23648.1 - 0.00018 21.2 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 FAM176 family Amastin PF07344.11 OEU23648.1 - 0.00056 19.8 0.2 0.011 15.6 0.5 2.1 1 1 1 2 2 2 1 Amastin surface glycoprotein RXT2_N PF08595.11 OEU23648.1 - 0.0012 18.9 1.0 0.014 15.4 1.2 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal DUF4834 PF16118.5 OEU23648.1 - 0.0014 19.6 2.6 1.4 10.0 0.2 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4834) Orf78 PF06024.12 OEU23648.1 - 0.0014 18.9 6.6 0.16 12.3 0.1 3.2 2 1 1 3 3 3 2 Orf78 (ac78) DNApol_Exo PF18136.1 OEU23648.1 - 0.0031 16.7 0.9 0.0045 16.2 0.1 1.6 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain Ctr PF04145.15 OEU23648.1 - 0.0043 17.7 0.1 0.019 15.6 0.1 1.9 1 1 0 1 1 1 1 Ctr copper transporter family TMEM51 PF15345.6 OEU23648.1 - 0.0093 15.8 2.3 2.2 8.1 0.0 2.2 2 1 0 2 2 2 2 Transmembrane protein 51 DUF3169 PF11368.8 OEU23648.1 - 0.013 15.0 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2956 PF11169.8 OEU23648.1 - 0.029 14.6 0.5 12 6.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) PBP1_TM PF14812.6 OEU23648.1 - 0.04 14.3 7.4 6.8 7.1 9.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAP2_C PF14360.6 OEU23648.1 - 0.079 13.5 5.8 2 9.0 0.7 3.0 3 0 0 3 3 3 0 PAP2 superfamily C-terminal AIM3 PF17096.5 OEU23648.1 - 1.2 10.1 7.6 35 5.4 4.5 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Claudin_2 PF13903.6 OEU23648.1 - 2.8 7.6 5.8 0.29 10.9 0.1 2.3 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF3915 PF13054.6 OEU23648.1 - 4.7 7.2 7.7 15 5.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) Gln-synt_C PF00120.24 OEU23650.1 - 1.7e-67 227.9 0.0 2.3e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain UPF0242 PF06785.11 OEU23651.1 - 0.0066 16.6 5.6 0.016 15.4 4.9 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Sec3_C_2 PF15278.6 OEU23651.1 - 0.01 16.1 0.2 0.02 15.2 0.2 1.4 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DASH_Ask1 PF08655.10 OEU23652.1 - 0.047 13.6 0.7 0.14 12.1 0.7 1.8 1 0 0 1 1 1 0 DASH complex subunit Ask1 Sulfotransfer_3 PF13469.6 OEU23652.1 - 0.07 13.5 2.7 2.7 8.3 0.5 3.2 2 1 0 2 2 2 0 Sulfotransferase family PH_11 PF15413.6 OEU23652.1 - 5.3 7.5 9.6 0.34 11.3 1.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain Ank_4 PF13637.6 OEU23653.1 - 4.3e-05 24.0 0.6 0.00031 21.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU23653.1 - 0.0013 19.3 0.0 1.1 9.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Mis14 PF08641.12 OEU23653.1 - 0.051 13.9 5.2 0.14 12.5 5.2 1.7 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Ank_5 PF13857.6 OEU23653.1 - 0.068 13.5 0.0 26 5.3 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Se-cys_synth_N PF12390.8 OEU23653.1 - 0.15 12.3 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 Selenocysteine synthase N terminal FliL PF03748.14 OEU23653.1 - 0.19 12.3 2.7 0.48 11.0 2.3 1.9 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL sCache_like PF16736.5 OEU23653.1 - 0.89 9.7 4.6 16 5.6 0.1 2.5 1 1 1 2 2 2 0 Single Cache-like Methyltransf_16 PF10294.9 OEU23655.1 - 0.00059 19.6 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Presenilin PF01080.17 OEU23655.1 - 9.5 4.9 7.6 3.1 6.5 4.5 1.7 2 0 0 2 2 2 0 Presenilin FAM176 PF14851.6 OEU23656.1 - 0.14 11.8 1.7 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.10 OEU23656.1 - 0.18 11.8 2.2 0.34 11.0 2.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAF1-p150_C2 PF15539.6 OEU23656.1 - 0.27 10.6 10.7 0.015 14.8 4.8 1.8 2 1 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term ADH_N PF08240.12 OEU23657.1 - 0.00021 21.2 0.0 0.00063 19.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OEU23657.1 - 0.00051 21.1 0.0 0.0022 19.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1778 PF08681.11 OEU23658.1 - 0.068 13.1 2.0 0.3 11.0 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1778) Phage_fiber_2 PF03406.13 OEU23658.1 - 0.13 11.8 2.2 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Phage tail fibre repeat ChaB PF06150.12 OEU23658.1 - 0.21 12.2 1.8 13 6.5 0.7 2.4 2 0 0 2 2 2 0 ChaB CSD PF00313.22 OEU23659.1 - 4.1e-22 77.8 2.3 5e-22 77.5 2.3 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OEU23659.1 - 0.00035 20.2 0.9 0.00058 19.5 0.9 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain DUF2167 PF09935.9 OEU23659.1 - 0.058 12.5 0.0 0.067 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Interferon PF00143.19 OEU23660.1 - 0.084 13.1 1.5 0.22 11.7 1.5 1.6 1 0 0 1 1 1 0 Interferon alpha/beta domain EphA2_TM PF14575.6 OEU23660.1 - 0.3 12.0 2.2 0.59 11.1 0.0 2.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.16 OEU23660.1 - 2.6 8.0 8.4 1.2 9.1 0.9 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tox-WTIP PF15654.6 OEU23660.1 - 5.1 7.6 5.4 23 5.5 0.2 3.7 3 0 0 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif Membralin PF09746.9 OEU23661.1 - 1e-07 31.4 5.8 1e-07 31.4 5.8 4.5 4 1 0 4 4 4 1 Tumour-associated protein CENP-B_dimeris PF09026.10 OEU23663.1 - 0.0047 17.3 3.1 0.01 16.2 3.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PD40 PF07676.12 OEU23664.1 - 0.16 11.9 3.1 0.56 10.2 0.1 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 OEU23664.1 - 0.39 11.7 2.2 6.3 7.8 0.0 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat Melibiase_2 PF16499.5 OEU23665.1 - 6e-64 215.9 1.6 1e-63 215.2 1.6 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OEU23665.1 - 3.3e-16 59.1 0.3 3.3e-16 59.1 0.3 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OEU23665.1 - 0.00042 19.4 0.0 0.00078 18.5 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 OEU23665.1 - 0.042 14.1 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain DUF3215 PF11503.8 OEU23665.1 - 0.049 13.5 0.1 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) TMEM154 PF15102.6 OEU23666.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 3.7 4 0 0 4 4 4 1 TMEM154 protein family LST1 PF05083.13 OEU23666.1 - 0.04 14.2 1.1 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 LST-1 protein LSR PF05624.14 OEU23666.1 - 0.075 13.0 5.0 0.14 12.2 5.0 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) EphA2_TM PF14575.6 OEU23666.1 - 0.12 13.3 7.9 0.91 10.5 4.7 3.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 OEU23666.1 - 0.87 8.3 5.5 0.68 8.6 2.4 2.2 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF908 PF06012.12 OEU23666.1 - 1.6 8.0 10.9 0.14 11.5 1.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) LRR19-TM PF15176.6 OEU23666.1 - 1.6 8.7 4.8 29 4.7 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Tmemb_9 PF05434.11 OEU23666.1 - 3.3 7.6 0.0 3.3 7.6 0.0 3.1 3 0 0 3 3 3 0 TMEM9 LRR_4 PF12799.7 OEU23667.1 - 1.8e-10 40.9 20.1 0.0023 18.3 0.2 5.6 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OEU23667.1 - 2.6e-09 36.7 19.6 0.0019 17.9 0.2 4.5 2 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 OEU23667.1 - 1.1e-07 31.4 12.0 1.6 9.5 0.1 7.1 7 2 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 OEU23667.1 - 3.9e-06 26.5 13.6 0.41 10.8 0.1 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_2 PF07723.13 OEU23667.1 - 0.21 12.3 2.4 41 5.1 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat DHQS PF01959.16 OEU23668.1 - 2.8e-48 164.6 1.2 6.6e-37 127.2 0.0 3.2 3 0 0 3 3 3 3 3-dehydroquinate synthase II GrpE PF01025.19 OEU23669.1 - 0.032 13.9 3.6 0.057 13.1 3.6 1.3 1 0 0 1 1 1 0 GrpE BEX PF04538.12 OEU23669.1 - 0.051 14.2 5.1 0.29 11.7 4.8 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family LacI PF00356.21 OEU23669.1 - 0.14 11.9 0.3 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Nop16 PF09420.10 OEU23669.1 - 0.17 11.9 6.6 0.31 11.0 6.6 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Rrn6 PF10214.9 OEU23669.1 - 0.17 10.3 2.7 0.25 9.8 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Na_Ca_ex_C PF16494.5 OEU23669.1 - 0.51 10.8 8.4 1.8 9.1 4.8 2.5 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain AA_permease_2 PF13520.6 OEU23670.1 - 1.5e-21 76.8 7.6 1.5e-21 76.8 7.6 2.3 3 0 0 3 3 3 2 Amino acid permease AA_permease PF00324.21 OEU23670.1 - 5e-13 48.5 6.0 5e-13 48.5 6.0 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OEU23670.1 - 3.1e-07 30.4 7.4 3.1e-07 30.4 7.4 2.2 2 0 0 2 2 2 1 C-terminus of AA_permease Radial_spoke PF04712.12 OEU23672.1 - 0.025 13.5 0.5 0.03 13.3 0.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein YlbD_coat PF14071.6 OEU23672.1 - 0.54 10.5 4.2 0.17 12.1 0.4 2.0 2 0 0 2 2 2 0 Putative coat protein GAPES2 PF17156.4 OEU23673.1 - 0.0002 21.2 0.1 0.00026 20.8 0.1 1.2 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain HR1 PF02185.16 OEU23673.1 - 0.0085 16.2 1.5 0.011 15.8 0.5 1.8 2 0 0 2 2 2 1 Hr1 repeat DivIC PF04977.15 OEU23673.1 - 0.14 11.9 2.7 2.2 8.1 3.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Synaptobrevin PF00957.21 OEU23674.1 - 0.058 13.2 2.4 0.07 12.9 2.4 1.1 1 0 0 1 1 1 0 Synaptobrevin UL41A PF17591.2 OEU23674.1 - 0.095 12.8 2.6 0.11 12.6 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL41A Thr_synth_N PF14821.6 OEU23675.1 - 1.1e-23 83.2 0.0 2.8e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 OEU23675.1 - 1.3e-06 28.1 0.0 2e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ntox44 PF15607.6 OEU23675.1 - 0.015 15.6 0.8 0.28 11.5 0.0 2.7 2 0 0 2 2 2 0 Bacterial toxin 44 DNA_pack_C PF02499.15 OEU23675.1 - 0.027 13.4 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus SR-25 PF10500.9 OEU23676.1 - 0.0002 21.0 5.2 0.00031 20.4 5.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SopD PF11047.8 OEU23676.1 - 0.046 12.9 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Salmonella outer protein D IMUP PF15761.5 OEU23676.1 - 0.43 11.3 4.9 0.84 10.4 4.9 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein PGAP1 PF07819.13 OEU23677.1 - 2.8e-08 33.8 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 OEU23677.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OEU23677.1 - 0.0016 18.2 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 OEU23677.1 - 0.0051 16.0 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 OEU23677.1 - 0.011 16.4 0.3 0.017 15.7 0.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OEU23677.1 - 0.022 14.0 0.0 0.27 10.4 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Mg-por_mtran_C PF07109.11 OEU23679.1 - 0.086 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus HA PF03457.14 OEU23680.1 - 5.7e-17 61.8 1.3 9.1e-17 61.2 1.3 1.4 1 0 0 1 1 1 1 Helicase associated domain HSCB_C PF07743.13 OEU23681.1 - 3e-10 40.5 9.4 1e-09 38.7 9.4 1.9 1 1 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OEU23681.1 - 6.7e-07 29.4 2.5 1.6e-06 28.1 0.5 2.4 2 0 0 2 2 2 1 DnaJ domain adh_short PF00106.25 OEU23682.1 - 6.7e-23 81.2 0.0 1.4e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OEU23682.1 - 6.2e-08 32.5 0.0 0.00089 18.9 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Chloroa_b-bind PF00504.21 OEU23685.1 - 1.8e-32 113.1 0.0 2.3e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HTH_1 PF00126.27 OEU23685.1 - 0.15 12.0 0.2 0.27 11.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SQS_PSY PF00494.19 OEU23686.1 - 3.7e-37 128.3 0.0 7.5e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase POX PF07526.11 OEU23686.1 - 6.7 7.3 10.2 4.9 7.7 0.2 3.5 4 1 1 5 5 5 0 Associated with HOX Sugar_tr PF00083.24 OEU23689.1 - 1.6e-102 343.7 27.5 1.2e-79 268.3 16.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OEU23689.1 - 3.9e-31 108.3 19.9 3.9e-31 108.3 19.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OEU23689.1 - 0.0041 15.6 3.8 0.0041 15.6 3.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex14_N PF04695.13 OEU23689.1 - 0.078 13.6 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3425 PF11905.8 OEU23689.1 - 0.11 12.4 0.0 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OEU23690.1 - 1.4e-08 34.7 14.8 1.8e-08 34.3 13.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OEU23690.1 - 2.5e-06 27.5 9.8 7.6e-06 25.9 9.8 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OEU23690.1 - 0.00048 20.6 8.0 0.0041 17.6 8.2 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor 2_5_RNA_ligase2 PF13563.6 OEU23692.1 - 2.4e-16 60.0 0.3 2.9e-07 30.5 0.0 2.6 2 1 0 2 2 2 2 2'-5' RNA ligase superfamily FTZ PF03867.14 OEU23692.1 - 0.39 10.2 4.7 0.76 9.3 4.7 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SMN PF06003.12 OEU23692.1 - 2.5 7.3 6.7 0.13 11.5 0.7 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) SDA1 PF05285.12 OEU23693.1 - 7.9e-33 114.3 29.7 7.9e-33 114.3 29.7 2.8 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 OEU23693.1 - 4.9e-05 23.6 0.2 0.00011 22.4 0.2 1.6 1 0 0 1 1 1 1 NUC130/3NT domain Nup54_57_C PF18570.1 OEU23693.1 - 0.022 14.4 0.0 0.076 12.6 0.0 2.0 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain IPK PF03770.16 OEU23693.1 - 0.025 14.4 0.3 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Inositol polyphosphate kinase Helicase_C PF00271.31 OEU23694.1 - 4.6e-13 49.5 0.0 3.8e-12 46.5 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 OEU23694.1 - 0.012 15.9 3.3 0.03 14.7 3.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 OEU23694.1 - 0.014 15.6 0.6 0.033 14.5 0.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 OEU23694.1 - 0.21 11.2 3.4 0.48 10.1 3.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OEU23694.1 - 5.3 7.0 7.0 3.6 7.5 4.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Adeno_E1B_19K PF01691.16 OEU23695.1 - 0.16 11.5 0.0 13 5.3 0.0 2.4 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen Band_7 PF01145.25 OEU23696.1 - 1.5e-31 109.8 0.0 1.5e-31 109.8 0.0 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 OEU23696.1 - 0.017 15.3 6.2 0.017 15.3 6.2 2.3 2 0 0 2 2 2 0 Flotillin Peptidase_M3 PF01432.20 OEU23697.1 - 3.1e-64 218.0 0.0 3.4e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OEU23697.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase M50B-like Mito_carr PF00153.27 OEU23698.1 - 0.03 14.2 3.4 0.66 9.9 0.1 4.2 5 1 0 5 5 5 0 Mitochondrial carrier protein GST_C PF00043.25 OEU23699.1 - 2.3e-11 43.8 0.1 4.5e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OEU23699.1 - 1.6e-09 37.7 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OEU23699.1 - 1.8e-07 31.4 0.0 1.6e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OEU23699.1 - 4.8e-07 30.0 0.0 1.5e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OEU23699.1 - 1.1e-05 25.5 0.1 2.1e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OEU23699.1 - 2.1e-05 24.9 0.0 0.00015 22.1 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain CcmH PF03918.14 OEU23699.1 - 0.043 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GST_C_5 PF16865.5 OEU23699.1 - 0.051 14.2 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OEU23699.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PhyH PF05721.13 OEU23700.1 - 4.3e-08 33.7 0.1 7.7e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF836 PF05768.14 OEU23701.1 - 2.9e-13 50.0 0.7 4e-13 49.6 0.7 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 OEU23701.1 - 0.0018 18.4 0.1 0.0035 17.5 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin DUF3888 PF13027.6 OEU23701.1 - 0.076 13.5 0.7 0.11 13.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Thioredoxin_3 PF13192.6 OEU23701.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Tim17 PF02466.19 OEU23702.1 - 1.4e-08 35.1 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 2OG-FeII_Oxy PF03171.20 OEU23703.1 - 4.4e-05 23.9 1.5 0.0038 17.7 0.6 3.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Voldacs PF03517.13 OEU23703.1 - 0.012 15.7 12.6 0.053 13.6 0.6 3.7 3 1 0 3 3 3 0 Regulator of volume decrease after cellular swelling Pertussis_S2S3 PF02918.15 OEU23703.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain FAM163 PF15069.6 OEU23703.1 - 4.5 7.7 6.0 3.8 7.9 4.2 1.8 1 1 0 1 1 1 0 FAM163 family Ank PF00023.30 OEU23704.1 - 2.7e-06 27.6 3.0 0.00028 21.2 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OEU23704.1 - 8.3e-06 26.0 0.4 0.14 12.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OEU23704.1 - 1.7e-05 25.3 0.1 3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OEU23704.1 - 0.00045 20.7 0.2 1.6 9.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OEU23704.1 - 0.0011 19.3 2.0 0.53 11.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Snf7 PF03357.21 OEU23706.1 - 1.2e-40 138.9 13.7 1.6e-40 138.6 13.7 1.1 1 0 0 1 1 1 1 Snf7 Spc7 PF08317.11 OEU23706.1 - 0.052 12.4 4.2 1.1 8.0 6.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DASH_Dad4 PF08650.10 OEU23706.1 - 0.067 13.2 2.1 0.21 11.6 1.9 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad4 FAD_binding_3 PF01494.19 OEU23707.1 - 0.031 13.5 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PPR_long PF17177.4 OEU23707.1 - 0.092 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP tRNA_U5-meth_tr PF05958.11 OEU23708.1 - 0.01 14.9 0.1 0.034 13.1 0.1 1.8 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase zf-MYND PF01753.18 OEU23709.1 - 9.1e-07 28.9 3.4 1.5e-06 28.1 3.3 1.4 1 1 0 1 1 1 1 MYND finger Carla_C4 PF01623.17 OEU23709.1 - 0.085 12.8 1.9 0.13 12.3 1.9 1.3 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein zf-C6H2 PF15801.5 OEU23709.1 - 0.63 10.4 9.1 0.94 9.8 3.1 2.2 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding CIA30 PF08547.12 OEU23710.1 - 1e-20 74.4 0.0 1.4e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) UbiA PF01040.18 OEU23711.1 - 3e-48 164.3 12.6 5.3e-48 163.5 12.6 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Transport_MerF PF11431.8 OEU23711.1 - 1.8 8.5 4.9 0.55 10.2 0.9 2.3 2 0 0 2 2 2 0 Membrane transport protein MerF Cyclin_N PF00134.23 OEU23714.1 - 2.3e-24 85.6 0.0 4.7e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Macoilin PF09726.9 OEU23714.1 - 0.0024 16.5 9.3 0.0026 16.4 9.3 1.1 1 0 0 1 1 1 1 Macoilin family Pneumo_att_G PF05539.11 OEU23714.1 - 0.58 9.7 18.1 0.77 9.3 18.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Podoplanin PF05808.11 OEU23714.1 - 2.5 8.2 10.5 4.8 7.3 10.5 1.5 1 0 0 1 1 1 0 Podoplanin PAP1 PF08601.10 OEU23714.1 - 4 7.1 19.6 5.4 6.6 19.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ras PF00071.22 OEU23715.1 - 7.9e-68 227.1 0.8 9e-68 227.0 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OEU23715.1 - 6.1e-37 126.5 0.8 8.9e-37 126.0 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OEU23715.1 - 4e-18 65.5 0.1 4.8e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OEU23715.1 - 4.5e-06 26.7 0.5 0.084 12.8 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OEU23715.1 - 6.3e-06 25.7 0.0 1.1e-05 24.9 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OEU23715.1 - 6.6e-06 26.2 0.1 2.9e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OEU23715.1 - 1.4e-05 24.6 0.1 1.6e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OEU23715.1 - 3.8e-05 23.3 0.3 0.00011 21.8 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OEU23715.1 - 0.00026 20.5 0.2 0.15 11.5 0.0 2.1 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 OEU23715.1 - 0.013 16.0 0.1 0.2 12.1 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OEU23715.1 - 0.014 15.8 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 OEU23715.1 - 0.021 14.4 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OEU23715.1 - 0.022 14.5 0.1 0.74 9.5 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OEU23715.1 - 0.035 14.4 0.0 0.052 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OEU23715.1 - 0.037 14.0 0.1 0.085 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OEU23715.1 - 0.039 13.7 0.1 0.7 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OEU23715.1 - 0.046 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OEU23715.1 - 0.056 14.0 0.1 0.081 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 OEU23715.1 - 0.058 12.7 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin LANC_like PF05147.13 OEU23715.1 - 0.08 11.5 0.0 0.18 10.3 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein TniB PF05621.11 OEU23715.1 - 0.091 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Dioxygenase_N PF04444.14 OEU23715.1 - 0.12 12.2 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Catechol dioxygenase N terminus DUF3533 PF12051.8 OEU23715.1 - 0.16 10.9 0.3 0.19 10.6 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Pyr_redox_2 PF07992.14 OEU23716.1 - 3.2e-41 141.5 1.7 1.6e-39 135.9 1.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OEU23716.1 - 5.9e-22 78.3 2.0 1e-15 57.8 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 OEU23716.1 - 2.7e-19 69.1 0.0 6.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 OEU23716.1 - 8.3e-17 61.5 0.6 1.5e-13 51.1 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OEU23716.1 - 1.9e-07 31.5 0.1 0.00063 20.2 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.7 OEU23716.1 - 2e-07 30.7 1.7 3.9e-05 23.2 1.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OEU23716.1 - 3e-06 27.1 4.6 0.078 12.6 0.7 3.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 OEU23716.1 - 7.2e-06 25.3 6.7 0.0018 17.5 0.5 4.3 5 0 0 5 5 5 2 Glucose inhibited division protein A Thioredoxin_2 PF13098.6 OEU23716.1 - 4.3e-05 23.9 0.2 0.00024 21.5 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain FAD_binding_2 PF00890.24 OEU23716.1 - 5.1e-05 22.5 8.4 0.0012 18.0 1.6 3.5 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 OEU23716.1 - 0.0001 21.1 5.8 0.01 14.6 1.9 3.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 OEU23716.1 - 0.00013 22.1 1.5 0.007 16.6 0.4 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU23716.1 - 0.001 18.4 0.5 0.24 10.6 0.4 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OEU23716.1 - 0.0014 18.0 6.3 0.065 12.5 1.7 2.9 3 0 0 3 3 3 2 FAD binding domain OST3_OST6 PF04756.13 OEU23716.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family FMO-like PF00743.19 OEU23716.1 - 0.0086 14.6 0.1 0.02 13.4 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like TraF PF13728.6 OEU23716.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OEU23716.1 - 0.025 14.8 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like K_oxygenase PF13434.6 OEU23716.1 - 0.031 13.4 0.8 0.11 11.6 0.0 2.2 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Spermine_synth PF01564.17 OEU23716.1 - 0.15 11.4 0.1 0.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Trp_halogenase PF04820.14 OEU23716.1 - 0.3 9.9 1.9 3 6.6 1.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OEU23716.1 - 0.39 10.0 1.7 3.1 7.0 0.5 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OEU23716.1 - 0.9 9.5 4.1 47 3.9 0.1 3.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OEU23716.1 - 2.1 7.3 3.9 2.2 7.3 0.9 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein peroxidase PF00141.23 OEU23717.1 - 6.7e-38 130.7 0.0 9.6e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 OEU23718.1 - 2.2e-38 132.2 0.0 3.1e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Thioredoxin_8 PF13905.6 OEU23719.1 - 1.1e-19 70.5 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU23719.1 - 2.4e-09 37.0 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU23719.1 - 8.4e-09 35.4 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 OEU23719.1 - 6.2e-06 26.1 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU23719.1 - 9.6e-05 22.8 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU23719.1 - 0.0039 16.9 0.0 0.092 12.5 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU23719.1 - 0.0052 16.9 0.0 0.048 13.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 OEU23719.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OEU23719.1 - 0.16 12.2 0.0 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.6 OEU23720.1 - 8.8e-20 70.8 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU23720.1 - 1.8e-09 37.5 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU23720.1 - 6.1e-09 35.8 0.0 8.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 OEU23720.1 - 4.9e-06 26.5 0.0 8.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU23720.1 - 7.3e-05 23.2 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU23720.1 - 0.0028 17.4 0.0 0.069 12.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU23720.1 - 0.0037 17.4 0.0 0.037 14.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 OEU23720.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OEU23720.1 - 0.12 12.7 0.0 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.6 OEU23721.1 - 8.1e-20 71.0 0.0 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OEU23721.1 - 1.7e-09 37.5 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OEU23721.1 - 5.6e-09 36.0 0.0 7.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 OEU23721.1 - 4.5e-06 26.6 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OEU23721.1 - 6.7e-05 23.3 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OEU23721.1 - 0.0025 17.6 0.0 0.063 13.1 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OEU23721.1 - 0.0034 17.5 0.0 0.034 14.3 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 OEU23721.1 - 0.056 13.3 0.0 0.099 12.4 0.0 1.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OEU23721.1 - 0.11 12.8 0.0 0.52 10.6 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin Peptidase_M24 PF00557.24 OEU23722.1 - 1.1e-51 175.5 0.0 1.5e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OEU23722.1 - 1.9e-23 82.5 0.0 4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 OEU23723.1 - 9.5e-52 175.7 0.0 1.3e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OEU23723.1 - 1.7e-23 82.7 0.0 3.6e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Mito_carr PF00153.27 OEU23724.1 - 4.8e-58 193.1 3.3 2.2e-18 65.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 OEU23725.1 - 4.2e-58 193.3 3.3 2.1e-18 66.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aconitase_2_N PF06434.13 OEU23726.1 - 1.2e-90 302.6 0.0 2.4e-90 301.6 0.0 1.5 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 OEU23726.1 - 1.1e-49 168.5 0.0 1.6e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 OEU23726.1 - 2e-42 145.8 0.0 1.7e-40 139.5 0.0 2.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) ILVD_EDD PF00920.21 OEU23727.1 - 7.1e-203 674.9 0.0 8.3e-203 674.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DXP_reductoisom PF02670.16 OEU23728.1 - 4.6e-41 140.5 1.2 7.8e-41 139.8 1.2 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 OEU23728.1 - 2e-36 124.8 0.0 5.5e-36 123.3 0.0 1.7 2 0 0 2 2 2 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 OEU23728.1 - 8.5e-35 118.8 0.0 2.8e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain IspD PF01128.19 OEU23729.1 - 1.8e-49 168.5 0.0 6.4e-49 166.7 0.0 1.7 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 OEU23729.1 - 4.4e-07 30.4 0.0 9.9e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain YgbB PF02542.16 OEU23730.1 - 5e-59 199.0 0.0 6.9e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 YgbB family LYTB PF02401.18 OEU23731.1 - 7.5e-71 238.5 0.8 1.1e-70 237.9 0.8 1.2 1 0 0 1 1 1 1 LytB protein NnrU PF07298.11 OEU23732.1 - 1e-33 116.7 6.7 1.2e-33 116.4 3.8 2.0 2 0 0 2 2 2 1 NnrU protein PEMT PF04191.13 OEU23732.1 - 0.0076 16.6 0.7 0.0076 16.6 0.7 3.0 3 1 1 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 OEU23732.1 - 0.017 15.5 0.8 0.056 13.9 0.2 2.2 1 1 1 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 OEU23732.1 - 0.031 13.8 1.0 0.067 12.7 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) GPDPase_memb PF10110.9 OEU23732.1 - 0.13 11.0 3.4 1.8 7.3 0.3 2.4 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase FAD_binding_3 PF01494.19 OEU23733.1 - 3.2e-19 69.4 0.0 5.9e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OEU23733.1 - 7.8e-05 22.8 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OEU23733.1 - 0.0003 20.1 0.0 0.00052 19.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OEU23733.1 - 0.00041 19.7 0.1 0.0026 17.1 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OEU23733.1 - 0.00093 18.3 0.0 0.88 8.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 OEU23733.1 - 0.0019 17.3 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OEU23733.1 - 0.0046 16.6 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 OEU23733.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox PF00070.27 OEU23733.1 - 0.036 14.6 0.1 0.14 12.7 0.0 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OEU23733.1 - 0.087 11.9 0.0 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 OEU23733.1 - 0.43 9.8 0.0 0.43 9.8 0.0 2.2 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain Porphobil_deam PF01379.20 OEU23734.1 - 2.5e-75 252.5 0.1 3.2e-75 252.1 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OEU23734.1 - 3e-18 66.0 0.4 5.7e-18 65.1 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SBP_bac_3 PF00497.20 OEU23734.1 - 0.035 13.5 0.1 0.33 10.3 0.1 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Coprogen_oxidas PF01218.18 OEU23735.1 - 2.8e-133 443.2 0.5 3.4e-133 442.9 0.5 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase EDS1_EP PF18117.1 OEU23735.1 - 0.055 13.9 0.9 0.099 13.1 0.9 1.5 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain NAD_binding_10 PF13460.6 OEU23736.1 - 7.5e-16 58.5 0.5 1.5e-13 51.1 0.0 3.2 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OEU23736.1 - 3.7e-08 33.1 0.4 1e-07 31.7 0.0 2.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OEU23736.1 - 5.3e-08 32.7 2.8 6.9e-06 25.8 0.0 2.7 2 1 1 3 3 3 2 NmrA-like family RmlD_sub_bind PF04321.17 OEU23736.1 - 5e-05 22.5 0.2 8.7e-05 21.7 0.2 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain HIM1 PF08732.10 OEU23736.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 HIM1 3Beta_HSD PF01073.19 OEU23736.1 - 0.056 12.4 0.6 4.1 6.3 0.6 2.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PAS_9 PF13426.7 OEU23737.1 - 1.4e-18 67.0 0.0 3.7e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 OEU23737.1 - 2.1e-10 40.5 8.1 4.7e-10 39.4 8.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PAS PF00989.25 OEU23737.1 - 3.6e-07 30.2 0.0 8.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 OEU23737.1 - 5.6e-07 29.6 8.1 1.1e-06 28.6 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 OEU23737.1 - 0.00026 21.2 0.0 0.00061 20.0 0.0 1.6 1 1 0 1 1 1 1 PAS fold TSC22 PF01166.18 OEU23737.1 - 0.091 13.1 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 OEU23737.1 - 0.67 10.5 9.2 0.42 11.2 5.9 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Pkinase_Tyr PF07714.17 OEU23738.1 - 2.3e-46 158.2 0.0 3e-44 151.3 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 OEU23738.1 - 1.7e-45 155.5 0.0 3e-43 148.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Response_reg PF00072.24 OEU23738.1 - 4.8e-26 91.1 0.1 1.7e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 OEU23738.1 - 4.6e-25 88.3 0.7 1.2e-24 87.0 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phosphonate-bd PF12974.7 OEU23738.1 - 1.6e-18 67.2 0.0 3.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein HisKA PF00512.25 OEU23738.1 - 1.3e-15 57.2 0.4 3.6e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain APH PF01636.23 OEU23738.1 - 0.0084 16.1 0.1 0.096 12.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family TMEM154 PF15102.6 OEU23738.1 - 0.014 15.3 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 OEU23738.1 - 0.13 12.4 0.7 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PEPcase PF00311.17 OEU23739.1 - 6.1e-265 881.2 0.2 7.8e-265 880.9 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 OEU23739.1 - 0.002 16.7 0.0 0.0039 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase MnmE_helical PF12631.7 OEU23739.1 - 0.033 14.4 0.5 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 MnmE helical domain SKN1 PF03935.15 OEU23740.1 - 8.4e-60 202.6 10.9 1.2e-49 169.1 7.6 4.4 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) EGF_2 PF07974.13 OEU23740.1 - 0.02 15.3 8.7 0.02 15.3 8.7 2.8 3 0 0 3 3 3 0 EGF-like domain PFK PF00365.20 OEU23741.1 - 1.1e-50 172.6 0.1 3.6e-50 170.9 0.1 1.7 1 1 0 1 1 1 1 Phosphofructokinase LSDAT_euk PF18139.1 OEU23741.1 - 0.024 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM FabA PF07977.13 OEU23742.1 - 1.2e-32 112.4 0.0 1.5e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 OEU23742.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain Acyl-CoA_dh_1 PF00441.24 OEU23743.1 - 3.9e-34 118.0 0.0 5.3e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OEU23743.1 - 4.1e-10 39.7 0.0 7.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OEU23743.1 - 6.9e-09 36.1 0.0 1.7e-08 34.8 0.0 1.6 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OEU23743.1 - 1.9e-07 31.7 0.0 9.4e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SURNod19 PF07712.12 OEU23744.1 - 1.4e-14 53.7 4.0 1.8e-13 50.0 4.0 2.2 1 1 0 1 1 1 1 Stress up-regulated Nod 19 Bac_rhodopsin PF01036.18 OEU23745.1 - 5.3e-24 85.0 10.8 6.3e-24 84.8 10.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein COX7B PF05392.11 OEU23745.1 - 0.067 12.9 0.1 0.067 12.9 0.1 2.2 2 1 0 2 2 2 0 Cytochrome C oxidase chain VIIB FAD_binding_7 PF03441.14 OEU23746.1 - 1e-57 194.9 1.1 1.7e-57 194.2 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OEU23746.1 - 2.6e-20 73.1 0.0 5.3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase SNF2_N PF00176.23 OEU23747.1 - 1.5e-52 178.5 0.5 2.3e-52 177.9 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OEU23747.1 - 1.1e-13 51.5 0.0 3.7e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 OEU23747.1 - 1.8e-12 47.1 0.1 4.8e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 OEU23747.1 - 6.3e-10 39.3 0.1 2.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OEU23747.1 - 7.7e-09 35.5 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OEU23747.1 - 8.2e-05 22.4 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 OEU23747.1 - 0.032 13.5 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-RanBP PF00641.18 OEU23747.1 - 0.27 10.6 14.3 0.029 13.7 7.9 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others His_Phos_1 PF00300.22 OEU23748.1 - 9.1e-16 58.1 0.6 4.6e-06 26.5 0.0 3.4 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 OEU23748.1 - 2.6 8.0 16.8 6.2 6.7 16.8 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4611 PF15387.6 OEU23748.1 - 2.6 8.3 7.2 9 6.6 7.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3246 PF11596.8 OEU23748.1 - 3.2 7.1 8.4 38 3.6 6.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DNA_pol_phi PF04931.13 OEU23748.1 - 8.2 4.4 10.5 15 3.5 10.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi PGM_PMM_I PF02878.16 OEU23749.1 - 2e-11 43.7 0.3 9e-08 31.9 0.1 3.5 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OEU23749.1 - 3.6e-08 33.5 0.0 9.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OEU23749.1 - 0.0014 18.8 0.0 0.0042 17.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF3446 PF11928.8 OEU23749.1 - 0.25 11.7 5.8 2.3 8.6 0.4 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain GDP_Man_Dehyd PF16363.5 OEU23750.1 - 3.8e-65 220.5 0.1 2.1e-64 218.0 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OEU23750.1 - 3.1e-55 187.2 0.0 4.6e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OEU23750.1 - 3.4e-20 72.2 0.0 5.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OEU23750.1 - 1.4e-17 63.8 0.0 1.2e-16 60.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OEU23750.1 - 3.3e-13 49.4 0.0 5.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OEU23750.1 - 6.4e-08 32.1 0.0 1.4e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OEU23750.1 - 2.3e-06 27.6 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OEU23750.1 - 1.3e-05 24.8 0.0 0.00036 20.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OEU23750.1 - 0.00038 20.4 0.0 0.0018 18.2 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OEU23750.1 - 0.014 15.0 0.0 0.089 12.3 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Pyr_redox_2 PF07992.14 OEU23750.1 - 0.028 13.7 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OEU23750.1 - 0.032 14.5 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 OEU23750.1 - 0.049 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OEU23750.1 - 0.091 12.6 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_24 PF18404.1 OEU23751.1 - 1.8e-136 453.9 2.3 2.8e-136 453.2 2.3 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OEU23751.1 - 5.9e-24 85.4 1.2 4e-23 82.7 1.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OEU23751.1 - 6.1e-18 64.9 0.1 1.1e-14 54.5 0.0 2.8 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 OEU23751.1 - 3.7e-17 62.5 1.5 4.2e-16 59.1 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OEU23751.1 - 7.7e-08 32.2 0.3 1.6e-07 31.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_12 PF18400.1 OEU23751.1 - 1.2e-05 25.2 0.0 0.00012 21.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain DUF1641 PF07849.11 OEU23751.1 - 0.018 14.9 0.2 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) bZIP_1 PF00170.21 OEU23752.1 - 0.00061 19.8 7.5 0.002 18.2 7.5 1.9 1 0 0 1 1 1 1 bZIP transcription factor PAS_9 PF13426.7 OEU23752.1 - 0.099 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain ABC_tran PF00005.27 OEU23753.1 - 3.1e-32 111.9 0.3 6.8e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 OEU23753.1 - 2.8e-24 86.2 10.1 5.1e-24 85.4 7.2 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 OEU23753.1 - 4e-09 36.2 0.8 2.9e-07 30.1 0.1 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OEU23753.1 - 0.0019 18.5 0.4 0.014 15.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OEU23753.1 - 0.0064 16.9 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OEU23753.1 - 0.0071 16.9 4.0 0.015 15.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OEU23753.1 - 0.049 13.4 0.9 0.11 12.3 0.9 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OEU23753.1 - 0.067 13.0 0.3 0.5 10.1 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 OEU23753.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KASH PF10541.9 OEU23753.1 - 8.7 6.7 7.0 17 5.8 1.4 2.8 2 0 0 2 2 2 0 Nuclear envelope localisation domain Frataxin_Cyay PF01491.16 OEU23754.1 - 2.8e-28 98.2 1.4 5.1e-28 97.3 1.4 1.5 1 0 0 1 1 1 1 Frataxin-like domain UCR_Fe-S_N PF10399.9 OEU23754.1 - 0.055 12.8 0.5 0.055 12.8 0.5 1.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Capsid_VP7 PF17071.5 OEU23754.1 - 0.068 12.4 2.0 0.092 12.0 2.0 1.2 1 0 0 1 1 1 0 Outer capsid protein VP7 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fragilariopsis_cylindrus_CCMP1102-Fracy1/GCA_001750085.1_Fracy1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fragilariopsis_cylindrus_CCMP1102-Fracy1/GCA_001750085.1_Fracy1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fragilariopsis_cylindrus_CCMP1102-Fracy1/GCA_001750085.1_Fracy1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Diatomes/Fragilariopsis_cylindrus_CCMP1102-Fracy1/GCA_001750085.1_Fracy1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 09:25:33 2019 # [ok]